locus-tag	class	description
ICG51_RS00020	COG0590	tRNA wobble adenosine to inosine editing
ICG51_RS00075	COG0789	Transcriptional regulator
ICG51_RS00135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICG51_RS00140	COG2217	Heavy metal translocating P-type atpase
ICG51_RS00145	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ICG51_RS00155	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ICG51_RS00175	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICG51_RS00260	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ICG51_RS00275	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ICG51_RS00290	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ICG51_RS00310	COG3621	Patatin-like phospholipase
ICG51_RS00330	COG0415	Belongs to the DNA photolyase family
ICG51_RS00335	COG3706	GGDEF domain
ICG51_RS00340	COG3300	MHYT domain
ICG51_RS00340	COG5001	Diguanylate cyclase
ICG51_RS00345	COG0702	epimerase
ICG51_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_RS00370	COG3046	protein related to deoxyribodipyrimidine photolyase
ICG51_RS00395	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ICG51_RS00405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ICG51_RS00440	COG2217	Heavy metal translocating P-type atpase
ICG51_RS00480	COG0714	Associated with various cellular activities
ICG51_RS00510	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICG51_RS00515	COG2914	Belongs to the UPF0125 (RnfH) family
ICG51_RS00520	COG2867	negative regulation of translational initiation
ICG51_RS00525	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ICG51_RS00545	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ICG51_RS00560	COG0668	transmembrane transport
ICG51_RS00565	COG2199	diguanylate cyclase activity
ICG51_RS00570	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ICG51_RS00585	COG0519	Catalyzes the synthesis of GMP from XMP
ICG51_RS00585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ICG51_RS00605	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ICG51_RS00610	COG0746	molybdenum cofactor guanylyltransferase activity
ICG51_RS00620	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICG51_RS00640	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ICG51_RS00645	COG0105	UTP biosynthetic process
ICG51_RS00655	COG1024	Enoyl-CoA hydratase
ICG51_RS00655	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICG51_RS00660	COG0183	Belongs to the thiolase family
ICG51_RS00665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ICG51_RS00675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICG51_RS00680	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ICG51_RS00690	COG0776	regulation of translation
ICG51_RS00700	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ICG51_RS00705	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ICG51_RS00715	COG2957	Belongs to the agmatine deiminase family
ICG51_RS00720	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICG51_RS00765	COG1007	ATP synthesis coupled electron transport
ICG51_RS00795	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ICG51_RS00800	COG1034	ATP synthesis coupled electron transport
ICG51_RS00810	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ICG51_RS00815	COG0649	NAD binding
ICG51_RS00820	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICG51_RS00825	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICG51_RS00830	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ICG51_RS00840	COG2081	HI0933 family
ICG51_RS00850	COG1054	Belongs to the UPF0176 family
ICG51_RS00860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICG51_RS00870	COG3706	GGDEF domain
ICG51_RS00880	COG3279	Response regulator of the LytR AlgR family
ICG51_RS00900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICG51_RS00905	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ICG51_RS00910	COG0505	Belongs to the CarA family
ICG51_RS00915	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ICG51_RS00930	COG0484	heat shock protein binding
ICG51_RS00935	COG0443	Heat shock 70 kDa protein
ICG51_RS00940	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ICG51_RS00945	COG1420	regulation of RNA biosynthetic process
ICG51_RS00965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICG51_RS00970	COG2925	Exonuclease
ICG51_RS00995	COG0484	heat shock protein binding
ICG51_RS01005	COG1596	polysaccharide export
ICG51_RS01015	COG2203	Gaf domain
ICG51_RS01015	COG5001	Diguanylate cyclase
ICG51_RS01015	COG4251	negative regulation of phosphorylation
ICG51_RS01015	COG3706	GGDEF domain
ICG51_RS01020	COG0529	Catalyzes the synthesis of activated sulfate
ICG51_RS01020	COG2895	sulfate adenylyltransferase (ATP) activity
ICG51_RS01025	COG0175	sulfate reduction
ICG51_RS01030	COG0069	glutamate synthase activity
ICG51_RS01060	COG4221	oxidoreductase activity
ICG51_RS01075	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ICG51_RS01080	COG3706	GGDEF domain
ICG51_RS01100	COG3590	peptidase
ICG51_RS01105	COG0251	oxidation-reduction process
ICG51_RS01110	COG3655	Transcriptional regulator
ICG51_RS01145	COG3038	cytochrome b561
ICG51_RS01150	COG0204	Acyl-transferase
ICG51_RS01180	COG0813	purine-nucleoside phosphorylase activity
ICG51_RS01185	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ICG51_RS01190	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ICG51_RS01235	COG3706	GGDEF domain
ICG51_RS01255	COG1136	(ABC) transporter
ICG51_RS01260	COG2119	membrane
ICG51_RS01280	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ICG51_RS01315	COG1187	pseudouridine synthase activity
ICG51_RS01345	COG1619	proteins homologs of microcin C7 resistance protein MccF
ICG51_RS01350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ICG51_RS01370	COG0531	amino acid
ICG51_RS01380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICG51_RS01385	COG0418	dihydroorotase activity
ICG51_RS01390	COG2203	Gaf domain
ICG51_RS01390	COG2199	diguanylate cyclase activity
ICG51_RS01445	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ICG51_RS01445	COG1703	isobutyryl-CoA mutase activity
ICG51_RS01445	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ICG51_RS01460	COG1960	acyl-CoA dehydrogenase activity
ICG51_RS01470	COG3706	GGDEF domain
ICG51_RS01480	COG2197	response regulator
ICG51_RS01490	COG0840	transmembrane signaling receptor activity
ICG51_RS01495	COG0835	chemotaxis
ICG51_RS01500	COG0840	transmembrane signaling receptor activity
ICG51_RS01510	COG0840	transmembrane signaling receptor activity
ICG51_RS01520	COG0840	transmembrane signaling receptor activity
ICG51_RS01525	COG5001	Diguanylate cyclase
ICG51_RS01535	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ICG51_RS01555	COG3243	poly(R)-hydroxyalkanoic acid synthase
ICG51_RS01565	COG1183	phosphatidylcholine synthase activity
ICG51_RS01575	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_RS01585	COG1064	alcohol dehydrogenase
ICG51_RS01610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ICG51_RS01615	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ICG51_RS01640	COG2850	peptidyl-arginine hydroxylation
ICG51_RS01650	COG0567	Dehydrogenase, E1 component
ICG51_RS01675	COG0604	alcohol dehydrogenase
ICG51_RS01690	COG0678	peroxiredoxin activity
ICG51_RS01695	COG4953	penicillin-binding protein 1C
ICG51_RS01715	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ICG51_RS01755	COG2350	Protein conserved in bacteria
ICG51_RS01765	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ICG51_RS01770	COG1187	pseudouridine synthase activity
ICG51_RS01805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICG51_RS01810	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ICG51_RS01815	COG0436	Aminotransferase
ICG51_RS01820	COG4133	protoheme IX ABC transporter activity
ICG51_RS01830	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
ICG51_RS01860	COG3088	subunit of a heme lyase
ICG51_RS01870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICG51_RS01890	COG0438	transferase activity, transferring glycosyl groups
ICG51_RS01895	COG0671	phosphoesterase, PA-phosphatase related
ICG51_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_RS01915	COG0288	reversible hydration of carbon dioxide
ICG51_RS01930	COG1185	polyribonucleotide nucleotidyltransferase activity
ICG51_RS01935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ICG51_RS01955	COG0195	Participates in both transcription termination and antitermination
ICG51_RS01960	COG0779	Required for maturation of 30S ribosomal subunits
ICG51_RS01970	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ICG51_RS01975	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ICG51_RS01985	COG1674	ftsk spoiiie
ICG51_RS01990	COG0686	Belongs to the AlaDH PNT family
ICG51_RS01995	COG0492	ferredoxin-NADP+ reductase activity
ICG51_RS02005	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ICG51_RS02020	COG5001	Diguanylate cyclase
ICG51_RS02020	COG5002	protein histidine kinase activity
ICG51_RS02095	COG0582	viral genome integration into host DNA
ICG51_RS02105	COG0840	transmembrane signaling receptor activity
ICG51_RS02110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ICG51_RS02120	COG0019	diaminopimelate decarboxylase activity
ICG51_RS02135	COG4948	Mandelate Racemase Muconate Lactonizing
ICG51_RS02140	COG1737	Transcriptional regulator
ICG51_RS02150	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ICG51_RS02155	COG0527	aspartate kinase activity
ICG51_RS02155	COG0460	homoserine dehydrogenase
ICG51_RS02175	COG1012	belongs to the aldehyde dehydrogenase family
ICG51_RS02190	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ICG51_RS02220	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ICG51_RS02225	COG1570	exodeoxyribonuclease VII activity
ICG51_RS02230	COG5001	Diguanylate cyclase
ICG51_RS02235	COG1595	DNA-templated transcription, initiation
ICG51_RS02245	COG1132	(ABC) transporter
ICG51_RS02265	COG0166	Belongs to the GPI family
ICG51_RS02270	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ICG51_RS02285	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ICG51_RS02290	COG0617	tRNA 3'-terminal CCA addition
ICG51_RS02300	COG1201	RNA secondary structure unwinding
ICG51_RS02305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ICG51_RS02320	COG1187	pseudouridine synthase activity
ICG51_RS02330	COG0705	Rhomboid family
ICG51_RS02340	COG0625	glutathione transferase activity
ICG51_RS02375	COG4774	siderophore transport
ICG51_RS02430	COG3275	phosphorelay sensor kinase activity
ICG51_RS02435	COG1611	Belongs to the LOG family
ICG51_RS02445	COG2095	MarC family integral membrane protein
ICG51_RS02450	COG0300	oxidoreductase activity
ICG51_RS02455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ICG51_RS02500	COG2969	positive regulation of protein catabolic process
ICG51_RS02505	COG0625	glutathione transferase activity
ICG51_RS02510	COG2857	Cytochrome c1
ICG51_RS02515	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ICG51_RS02520	COG0723	plastoquinol--plastocyanin reductase activity
ICG51_RS02525	COG0741	lytic transglycosylase activity
ICG51_RS02540	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ICG51_RS02545	COG1702	phosphate starvation-inducible protein PhoH
ICG51_RS02550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ICG51_RS02555	COG4535	Mg2 and Co2 transporter CorC
ICG51_RS02575	COG0823	Involved in the tonB-independent uptake of proteins
ICG51_RS02575	COG1506	peptidase
ICG51_RS02580	COG1297	OPT oligopeptide transporter protein
ICG51_RS02605	COG0306	phosphate transporter
ICG51_RS02615	COG1253	flavin adenine dinucleotide binding
ICG51_RS02620	COG3300	MHYT domain
ICG51_RS02620	COG5001	Diguanylate cyclase
ICG51_RS02640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ICG51_RS02645	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ICG51_RS02650	COG1862	Preprotein translocase
ICG51_RS02655	COG0343	queuine tRNA-ribosyltransferase activity
ICG51_RS02660	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ICG51_RS02665	COG1522	sequence-specific DNA binding
ICG51_RS02670	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ICG51_RS02675	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ICG51_RS02705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICG51_RS02710	COG0405	Gamma-glutamyltransferase
ICG51_RS02715	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ICG51_RS02730	COG0742	ribosomal rna small subunit methyltransferase
ICG51_RS02735	COG0552	protein localization to endoplasmic reticulum
ICG51_RS02745	COG1194	a g-specific adenine glycosylase
ICG51_RS02750	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ICG51_RS02765	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ICG51_RS02770	COG4774	siderophore transport
ICG51_RS02795	COG0149	triose-phosphate isomerase activity
ICG51_RS02810	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ICG51_RS02825	COG0133	tryptophan synthase activity
ICG51_RS02830	COG0135	phosphoribosylanthranilate isomerase activity
ICG51_RS02835	COG0101	tRNA pseudouridine synthase activity
ICG51_RS02845	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ICG51_RS02850	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ICG51_RS02855	COG2890	protein-(glutamine-N5) methyltransferase activity
ICG51_RS02860	COG1999	signal sequence binding
ICG51_RS02865	COG0688	phosphatidylethanolamine metabolic process
ICG51_RS02875	COG0753	catalase activity
ICG51_RS02950	COG3189	MarR family transcriptional regulator
ICG51_RS02965	COG0433	COG0433 Predicted ATPase
ICG51_RS02970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICG51_RS02980	COG0513	Belongs to the DEAD box helicase family
ICG51_RS02995	COG1960	acyl-CoA dehydrogenase activity
ICG51_RS03010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ICG51_RS03015	COG3842	ATPase activity
ICG51_RS03020	COG1176	ABC-type spermidine putrescine transport system, permease component I
ICG51_RS03025	COG1177	transmembrane transport
ICG51_RS03035	COG0116	Belongs to the methyltransferase superfamily
ICG51_RS03035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ICG51_RS03055	COG1946	Acyl-CoA thioesterase
ICG51_RS03070	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ICG51_RS03100	COG1073	alpha beta
ICG51_RS03145	COG0776	regulation of translation
ICG51_RS03160	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ICG51_RS03170	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ICG51_RS03220	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ICG51_RS03225	COG0575	Belongs to the CDS family
ICG51_RS03230	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ICG51_RS03235	COG0750	zinc metalloprotease
ICG51_RS03255	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICG51_RS03260	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICG51_RS03280	COG0825	malonyl-CoA metabolic process
ICG51_RS03290	COG1722	exodeoxyribonuclease VII activity
ICG51_RS03295	COG0142	geranyltranstransferase activity
ICG51_RS03315	COG0312	modulator of DNA gyrase
ICG51_RS03325	COG0312	modulator of DNA gyrase
ICG51_RS03340	COG0424	maF-like protein
ICG51_RS03355	COG2261	transglycosylase associated protein
ICG51_RS03365	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ICG51_RS03370	COG0175	sulfate reduction
ICG51_RS03380	COG1648	precorrin-2 dehydrogenase activity
ICG51_RS03380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ICG51_RS03400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ICG51_RS03405	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ICG51_RS03410	COG0628	permease
ICG51_RS03425	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ICG51_RS03440	COG3932	Exopolysaccharide synthesis, ExoD
ICG51_RS03450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ICG51_RS03465	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ICG51_RS03480	COG0148	phosphopyruvate hydratase activity
ICG51_RS03485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ICG51_RS03525	COG0791	NLP P60 protein
ICG51_RS03530	COG0791	NLP P60 protein
ICG51_RS03540	COG4948	Mandelate Racemase Muconate Lactonizing
ICG51_RS03550	COG2197	response regulator
ICG51_RS03565	COG0142	geranyltranstransferase activity
ICG51_RS03575	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ICG51_RS03585	COG0527	aspartate kinase activity
ICG51_RS03595	COG0384	phenazine biosynthesis protein PhzF
ICG51_RS03630	COG1704	LemA family
ICG51_RS03650	COG1285	pathogenesis
ICG51_RS03655	COG0513	Belongs to the DEAD box helicase family
ICG51_RS03665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ICG51_RS03675	COG0701	Predicted permease
ICG51_RS03690	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ICG51_RS03705	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ICG51_RS03710	COG1309	transcriptional regulator
ICG51_RS03725	COG0010	Belongs to the arginase family
ICG51_RS03730	COG1228	amidohydrolase
ICG51_RS03755	COG0735	belongs to the Fur family
ICG51_RS03765	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ICG51_RS03775	COG2833	Protein of unknown function (DUF455)
ICG51_RS03790	COG0285	dihydrofolate synthase activity
ICG51_RS03825	COG0156	8-amino-7-oxononanoate synthase activity
ICG51_RS03830	COG1187	pseudouridine synthase activity
ICG51_RS03845	COG1902	pentaerythritol trinitrate reductase activity
ICG51_RS03845	COG0446	pyridine nucleotide-disulphide oxidoreductase
ICG51_RS03855	COG0625	glutathione transferase activity
ICG51_RS03870	COG0039	L-malate dehydrogenase activity
ICG51_RS03885	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ICG51_RS03890	COG1217	gtp-binding protein TYPA
ICG51_RS03905	COG0154	amidase activity
ICG51_RS03910	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ICG51_RS03915	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
ICG51_RS03920	COG0203	ribosomal protein L17
ICG51_RS03930	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ICG51_RS03945	COG0201	protein transport
ICG51_RS03950	COG0200	Binds to the 23S rRNA
ICG51_RS03955	COG1841	ribosomal large subunit assembly
ICG51_RS03965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ICG51_RS03970	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ICG51_RS03980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ICG51_RS03985	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ICG51_RS03995	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ICG51_RS04000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ICG51_RS04010	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ICG51_RS04015	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ICG51_RS04020	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ICG51_RS04030	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ICG51_RS04035	COG0089	rRNA binding
ICG51_RS04040	COG0088	Forms part of the polypeptide exit tunnel
ICG51_RS04045	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ICG51_RS04050	COG0051	transcription antitermination factor activity, RNA binding
ICG51_RS04055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICG51_RS04060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ICG51_RS04065	COG0049	tRNA binding
ICG51_RS04070	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ICG51_RS04075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ICG51_RS04085	COG0222	ribosome binding
ICG51_RS04100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ICG51_RS04105	COG0250	Participates in transcription elongation, termination and antitermination
ICG51_RS04120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ICG51_RS04145	COG0193	aminoacyl-tRNA hydrolase activity
ICG51_RS04155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ICG51_RS04165	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ICG51_RS04170	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ICG51_RS04180	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ICG51_RS04185	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ICG51_RS04210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICG51_RS04215	COG1295	ribonuclease BN
ICG51_RS04230	COG0457	Tetratricopeptide repeat
ICG51_RS04240	COG3227	Zinc metalloprotease (Elastase)
ICG51_RS04245	COG2151	metal-sulfur cluster biosynthetic enzyme
ICG51_RS04255	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ICG51_RS04290	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICG51_RS04290	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ICG51_RS04325	COG0583	DNA-binding transcription factor activity
ICG51_RS04335	COG2843	Capsule synthesis protein
ICG51_RS04355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ICG51_RS04370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICG51_RS04375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ICG51_RS04385	COG2096	Adenosyltransferase
ICG51_RS04390	COG0123	including yeast histone deacetylase and acetoin utilization protein
ICG51_RS04395	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ICG51_RS04400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICG51_RS04405	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ICG51_RS04410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICG51_RS04420	COG2967	ApaG domain
ICG51_RS04425	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ICG51_RS04440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ICG51_RS04445	COG0861	Integral membrane protein TerC family
ICG51_RS04450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ICG51_RS04455	COG1136	(ABC) transporter
ICG51_RS04455	COG0577	efflux transmembrane transporter activity
ICG51_RS04460	COG1136	(ABC) transporter
ICG51_RS04465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICG51_RS04470	COG0642	Histidine kinase
ICG51_RS04490	COG3956	TIGRFAM MazG family protein
ICG51_RS04495	COG1218	3'(2'),5'-bisphosphate nucleotidase
ICG51_RS04500	COG0494	nUDIX hydrolase
ICG51_RS04510	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ICG51_RS04525	COG0643	Histidine kinase
ICG51_RS04525	COG0784	Response regulator, receiver
ICG51_RS04525	COG2198	Histidine kinase
ICG51_RS04530	COG0840	transmembrane signaling receptor activity
ICG51_RS04550	COG0189	ligase activity
ICG51_RS04570	COG1199	ATP-dependent helicase activity
ICG51_RS04575	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ICG51_RS04595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICG51_RS04600	COG1643	Atp-dependent helicase
ICG51_RS04605	COG0783	Belongs to the Dps family
ICG51_RS04615	COG0514	ATP-dependent DNA helicase (RecQ)
ICG51_RS04620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICG51_RS04645	COG0488	(ABC) transporter
ICG51_RS04660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ICG51_RS04670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ICG51_RS04680	COG0745	RESPONSE REGULATOR receiver
ICG51_RS04705	COG0471	metal ion transport
ICG51_RS04705	COG3273	potassium ion transport
ICG51_RS04725	COG1970	mechanosensitive ion channel activity
ICG51_RS04735	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ICG51_RS04740	COG0280	phosphate acetyltransferase
ICG51_RS04740	COG0281	malic enzyme
ICG51_RS04745	COG0786	glutamate:sodium symporter activity
ICG51_RS04750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ICG51_RS04760	COG1162	GTPase activity
ICG51_RS04765	COG0436	Aminotransferase
ICG51_RS04775	COG3038	cytochrome b561
ICG51_RS04795	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ICG51_RS04810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ICG51_RS04825	COG1307	EDD domain protein, DegV family
ICG51_RS04845	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ICG51_RS04855	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ICG51_RS04870	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ICG51_RS04875	COG2863	cytochrome
ICG51_RS04895	COG0730	response to heat
ICG51_RS04900	COG0741	lytic transglycosylase activity
ICG51_RS04905	COG0617	tRNA 3'-terminal CCA addition
ICG51_RS04925	COG0300	oxidoreductase activity
ICG51_RS04930	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ICG51_RS04935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ICG51_RS04955	COG0358	DNA primase activity
ICG51_RS04960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ICG51_RS04960	COG2169	Transcriptional regulator
ICG51_RS04965	COG3145	DNA-N1-methyladenine dioxygenase activity
ICG51_RS04970	COG0109	protoheme IX farnesyltransferase activity
ICG51_RS04975	COG1612	heme a metabolic process
ICG51_RS05000	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ICG51_RS05015	COG1565	acr, cog1565
ICG51_RS05015	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ICG51_RS05035	COG0793	Belongs to the peptidase S41A family
ICG51_RS05040	COG4942	peptidase
ICG51_RS05045	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ICG51_RS05055	COG2234	aminopeptidase activity
ICG51_RS05095	COG1773	rubredoxin
ICG51_RS05100	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ICG51_RS05105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICG51_RS05115	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ICG51_RS05120	COG0346	lactoylglutathione lyase activity
ICG51_RS05125	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_RS05130	COG0671	phosphoesterase, PA-phosphatase related
ICG51_RS05135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ICG51_RS05140	COG0563	adenylate kinase activity
ICG51_RS05155	COG1872	DUF167
ICG51_RS05165	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ICG51_RS05170	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ICG51_RS05205	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ICG51_RS05205	COG2755	lipolytic protein G-D-S-L family
ICG51_RS05230	COG0438	transferase activity, transferring glycosyl groups
ICG51_RS05250	COG0438	transferase activity, transferring glycosyl groups
ICG51_RS05270	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ICG51_RS05275	COG0237	dephospho-CoA kinase activity
ICG51_RS05280	COG0494	nUDIX hydrolase
ICG51_RS05290	COG0739	heme binding
ICG51_RS05315	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ICG51_RS05320	COG1181	Belongs to the D-alanine--D-alanine ligase family
ICG51_RS05325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ICG51_RS05340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ICG51_RS05345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ICG51_RS05350	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ICG51_RS05360	COG3116	cell division
ICG51_RS05365	COG0275	rRNA processing
ICG51_RS05370	COG2001	Belongs to the MraZ family
ICG51_RS05390	COG3107	peptidoglycan biosynthetic process
ICG51_RS05395	COG0792	nuclease activity
ICG51_RS05400	COG0277	FAD linked oxidase domain protein
ICG51_RS05415	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICG51_RS05420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ICG51_RS05440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICG51_RS05440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ICG51_RS05450	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ICG51_RS05455	COG0488	(ABC) transporter
ICG51_RS05460	COG0284	orotidine-5'-phosphate decarboxylase activity
ICG51_RS05475	COG1450	Type ii and iii secretion system protein
ICG51_RS05490	COG3166	PFAM Fimbrial assembly family protein
ICG51_RS05495	COG3156	type II secretion system protein K
ICG51_RS05500	COG4795	General secretion pathway protein
ICG51_RS05505	COG2165	general secretion pathway protein
ICG51_RS05510	COG4970	Tfp pilus assembly protein FimT
ICG51_RS05515	COG2165	general secretion pathway protein
ICG51_RS05520	COG1459	type II secretion system
ICG51_RS05525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICG51_RS05530	COG0047	phosphoribosylformylglycinamidine synthase activity
ICG51_RS05530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ICG51_RS05535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ICG51_RS05540	COG4974	Belongs to the 'phage' integrase family
ICG51_RS05555	COG0795	lipopolysaccharide-transporting ATPase activity
ICG51_RS05565	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ICG51_RS05590	COG2132	Multicopper oxidase
ICG51_RS05620	COG1752	Esterase of the alpha-beta hydrolase superfamily
ICG51_RS05625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICG51_RS05630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICG51_RS05635	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ICG51_RS05645	COG1956	GAF domain-containing protein
ICG51_RS05655	COG4206	TonB-dependent receptor
ICG51_RS05660	COG1309	transcriptional regulator
ICG51_RS05675	COG1136	(ABC) transporter
ICG51_RS05685	COG0295	cytidine deaminase activity
ICG51_RS05690	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ICG51_RS05695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ICG51_RS05710	COG1136	(ABC) transporter
ICG51_RS05710	COG0577	efflux transmembrane transporter activity
ICG51_RS05720	COG1136	(ABC) transporter
ICG51_RS05720	COG0577	efflux transmembrane transporter activity
ICG51_RS05735	COG2205	protein histidine kinase activity
ICG51_RS05735	COG0745	RESPONSE REGULATOR receiver
ICG51_RS05735	COG4191	Histidine kinase
ICG51_RS05745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ICG51_RS05785	COG0739	heme binding
ICG51_RS05790	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ICG51_RS05795	COG2807	transmembrane transport
ICG51_RS05805	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ICG51_RS05815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ICG51_RS05830	COG2003	Belongs to the UPF0758 family
ICG51_RS05835	COG0018	arginyl-trna synthetase
ICG51_RS05845	COG4221	oxidoreductase activity
ICG51_RS05850	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ICG51_RS05850	COG2755	lipolytic protein G-D-S-L family
ICG51_RS05855	COG1166	arginine decarboxylase activity
ICG51_RS05865	COG3706	GGDEF domain
ICG51_RS05870	COG0347	Belongs to the P(II) protein family
ICG51_RS05880	COG0606	chelatase, subunit chli
ICG51_RS05900	COG3706	GGDEF domain
ICG51_RS05905	COG2224	Isocitrate lyase
ICG51_RS05910	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ICG51_RS05915	COG0583	DNA-binding transcription factor activity
ICG51_RS05940	COG4771	TonB-dependent receptor
ICG51_RS05960	COG1215	transferase activity, transferring glycosyl groups
ICG51_RS05990	COG0564	pseudouridine synthase activity
ICG51_RS06000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ICG51_RS06025	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ICG51_RS06030	COG0318	PFAM AMP-dependent synthetase and ligase
ICG51_RS06045	COG0596	Alpha beta hydrolase
ICG51_RS06065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICG51_RS06075	COG0612	Peptidase, M16
ICG51_RS06100	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ICG51_RS06105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICG51_RS06135	COG0697	spore germination
ICG51_RS06140	COG0408	coproporphyrinogen oxidase activity
ICG51_RS06160	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ICG51_RS06165	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ICG51_RS06165	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ICG51_RS06170	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ICG51_RS06175	COG1461	Dihydroxyacetone kinase
ICG51_RS06195	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ICG51_RS06225	COG3104	oligopeptide transport
ICG51_RS06230	COG3483	tryptophan 2,3-dioxygenase activity
ICG51_RS06245	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICG51_RS06265	COG0180	Tryptophanyl-tRNA synthetase
ICG51_RS06285	COG2323	membrane
ICG51_RS06295	COG1132	(ABC) transporter
ICG51_RS06305	COG0210	DNA helicase
ICG51_RS06320	COG0625	glutathione transferase activity
ICG51_RS06325	COG1506	peptidase
ICG51_RS06325	COG0823	Involved in the tonB-independent uptake of proteins
ICG51_RS06350	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ICG51_RS06385	COG0357	Ribosomal RNA small subunit methyltransferase G
ICG51_RS06390	COG1192	Involved in chromosome partitioning
ICG51_RS06395	COG1475	DNA binding
ICG51_RS06400	COG0463	Glycosyl transferase, family 2
ICG51_RS06420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ICG51_RS06430	COG1968	undecaprenyl-diphosphatase activity
ICG51_RS06435	COG0174	glutamine synthetase
ICG51_RS06445	COG0347	Belongs to the P(II) protein family
ICG51_RS06450	COG0004	ammonium transporteR
ICG51_RS06460	COG3023	N-Acetylmuramoyl-L-alanine amidase
ICG51_RS06465	COG0739	heme binding
ICG51_RS06475	COG3852	Histidine kinase
ICG51_RS06480	COG2204	response regulator
ICG51_RS06485	COG2032	superoxide dismutase activity
ICG51_RS06495	COG0183	Belongs to the thiolase family
ICG51_RS06500	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ICG51_RS06535	COG0493	'glutamate synthase
ICG51_RS06540	COG0070	glutamate synthase
ICG51_RS06540	COG0069	glutamate synthase activity
ICG51_RS06540	COG0067	glutamate synthase
ICG51_RS06555	COG2922	Belongs to the Smg family
ICG51_RS06560	COG0758	DNA mediated transformation
ICG51_RS06570	COG0242	peptide deformylase activity
ICG51_RS06580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ICG51_RS06580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ICG51_RS06585	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ICG51_RS06610	COG1490	D-aminoacyl-tRNA deacylase activity
ICG51_RS06615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ICG51_RS06620	COG0582	viral genome integration into host DNA
ICG51_RS06665	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ICG51_RS06670	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ICG51_RS06680	COG2205	protein histidine kinase activity
ICG51_RS06690	COG0210	DNA helicase
ICG51_RS06705	COG5377	YqaJ viral recombinase family
ICG51_RS06740	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ICG51_RS06750	COG4983	Phage plasmid primase, P4 family domain protein
ICG51_RS06770	COG2205	protein histidine kinase activity
ICG51_RS06775	COG0745	RESPONSE REGULATOR receiver
ICG51_RS06780	COG1368	sulfuric ester hydrolase activity
ICG51_RS06820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ICG51_RS06825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ICG51_RS06830	COG1127	ABC transporter
ICG51_RS06835	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ICG51_RS06840	COG1074	ATP-dependent DNA helicase activity
ICG51_RS06870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICG51_RS06875	COG3122	Protein conserved in bacteria
ICG51_RS06880	COG0534	Mate efflux family protein
ICG51_RS06900	COG1960	acyl-CoA dehydrogenase activity
ICG51_RS06920	COG0302	gtp cyclohydrolase
ICG51_RS06970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ICG51_RS07000	COG1505	serine-type exopeptidase activity
ICG51_RS07015	COG2378	regulation of single-species biofilm formation
ICG51_RS07025	COG0181	hydroxymethylbilane synthase activity
ICG51_RS07065	COG0745	RESPONSE REGULATOR receiver
ICG51_RS07075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ICG51_RS07080	COG0861	Integral membrane protein TerC family
ICG51_RS07090	COG3647	Membrane
ICG51_RS07095	COG1752	Esterase of the alpha-beta hydrolase superfamily
ICG51_RS07110	COG1595	DNA-templated transcription, initiation
ICG51_RS07115	COG0302	gtp cyclohydrolase
ICG51_RS07120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ICG51_RS07130	COG3186	Phenylalanine-4-hydroxylase
ICG51_RS07135	COG5487	UPF0391 membrane protein
ICG51_RS07140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ICG51_RS07145	COG3273	potassium ion transport
ICG51_RS07145	COG0471	metal ion transport
ICG51_RS07150	COG1741	Belongs to the pirin family
ICG51_RS07165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICG51_RS07215	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ICG51_RS07220	COG0592	DNA-directed DNA polymerase activity
ICG51_RS07240	COG0706	membrane insertase activity
ICG51_RS07260	COG4555	ABC transporter
ICG51_RS07305	COG1131	(ABC) transporter
ICG51_RS07310	COG0842	Transport permease protein
ICG51_RS07325	COG0084	hydrolase, TatD family'
ICG51_RS07330	COG1643	Atp-dependent helicase
ICG51_RS07340	COG2205	protein histidine kinase activity
ICG51_RS07345	COG1187	pseudouridine synthase activity
ICG51_RS07365	COG1652	LysM domain
ICG51_RS07370	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICG51_RS07370	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ICG51_RS07375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ICG51_RS07380	COG2945	thiolester hydrolase activity
ICG51_RS07425	COG1040	competence protein
ICG51_RS07430	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ICG51_RS07435	COG0156	8-amino-7-oxononanoate synthase activity
ICG51_RS07445	COG2267	carboxylic ester hydrolase activity
ICG51_RS07455	COG0697	spore germination
ICG51_RS07460	COG2205	protein histidine kinase activity
ICG51_RS07460	COG3437	response regulator, receiver
ICG51_RS07460	COG3850	Histidine kinase
ICG51_RS07460	COG4999	Histidine kinase
ICG51_RS07465	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ICG51_RS07470	COG2201	protein-glutamate methylesterase activity
ICG51_RS07475	COG5002	protein histidine kinase activity
ICG51_RS07480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ICG51_RS07495	COG2911	Protein conserved in bacteria
ICG51_RS07500	COG0729	surface antigen
ICG51_RS07505	COG2703	oxygen carrier activity
ICG51_RS07520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ICG51_RS07520	COG0519	Catalyzes the synthesis of GMP from XMP
ICG51_RS07550	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ICG51_RS07555	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICG51_RS07555	COG0596	Alpha beta hydrolase
ICG51_RS07575	COG0037	tRNA processing
ICG51_RS07585	COG2937	Belongs to the GPAT DAPAT family
ICG51_RS07590	COG5001	Diguanylate cyclase
ICG51_RS07590	COG3300	MHYT domain
ICG51_RS07605	COG0210	DNA helicase
ICG51_RS07625	COG1215	transferase activity, transferring glycosyl groups
ICG51_RS07650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ICG51_RS07650	COG2205	protein histidine kinase activity
ICG51_RS07660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ICG51_RS07685	COG1881	PFAM PEBP family protein
ICG51_RS07690	COG0515	serine threonine protein kinase
ICG51_RS07690	COG2815	serine threonine protein kinase
ICG51_RS07700	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ICG51_RS07715	COG1278	Cold shock
ICG51_RS07720	COG3590	peptidase
ICG51_RS07740	COG1238	metal cluster binding
ICG51_RS07745	COG2814	Major facilitator Superfamily
ICG51_RS07975	COG3162	membrane
ICG51_RS07985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ICG51_RS07995	COG2205	protein histidine kinase activity
ICG51_RS08005	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_RS08015	COG0616	signal peptide processing
ICG51_RS08020	COG0534	Mate efflux family protein
ICG51_RS08040	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ICG51_RS08050	COG2860	membrane
ICG51_RS08065	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ICG51_RS08080	COG2022	thiamine diphosphate biosynthetic process
ICG51_RS08095	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ICG51_RS08105	COG2226	methyltransferase
ICG51_RS08110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICG51_RS08120	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ICG51_RS08125	COG3118	belongs to the thioredoxin family
ICG51_RS08135	COG2884	Cell division ATP-binding protein ftsE
ICG51_RS08140	COG2177	Part of the ABC transporter FtsEX involved in
ICG51_RS08145	COG2201	protein-glutamate methylesterase activity
ICG51_RS08155	COG0308	aminopeptidase N
ICG51_RS08160	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICG51_RS08160	COG0596	Alpha beta hydrolase
ICG51_RS08175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICG51_RS08180	COG1077	Cell shape determining protein MreB Mrl
ICG51_RS08185	COG1792	Involved in formation and maintenance of cell shape
ICG51_RS08195	COG0768	penicillin binding
ICG51_RS08200	COG0772	Belongs to the SEDS family
ICG51_RS08205	COG2951	lytic endotransglycosylase activity
ICG51_RS08210	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ICG51_RS08215	COG1686	Belongs to the peptidase S11 family
ICG51_RS08220	COG2921	Belongs to the UPF0250 family
ICG51_RS08225	COG0321	lipoyl(octanoyl) transferase activity
ICG51_RS08240	COG0697	spore germination
ICG51_RS08250	COG0577	efflux transmembrane transporter activity
ICG51_RS08255	COG0577	efflux transmembrane transporter activity
ICG51_RS08260	COG1136	(ABC) transporter
ICG51_RS08265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ICG51_RS08270	COG1131	(ABC) transporter
ICG51_RS08280	COG4585	Histidine kinase
ICG51_RS08285	COG2197	response regulator
ICG51_RS08315	COG0628	permease
ICG51_RS08380	COG0693	protein deglycase activity
ICG51_RS08430	COG3040	lipid binding
ICG51_RS08440	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ICG51_RS08455	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ICG51_RS08465	COG2824	Alkylphosphonate utilization operon protein PhnA
ICG51_RS08485	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_RS08500	COG2079	MmgE PrpD family protein
ICG51_RS08510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ICG51_RS08535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ICG51_RS08540	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ICG51_RS08560	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ICG51_RS08565	COG0134	indole-3-glycerol-phosphate synthase activity
ICG51_RS08585	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ICG51_RS08600	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
ICG51_RS08605	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ICG51_RS08610	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ICG51_RS08630	COG0625	glutathione transferase activity
ICG51_RS08660	COG1450	Type ii and iii secretion system protein
ICG51_RS08710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ICG51_RS08715	COG1459	type II secretion system
ICG51_RS08745	COG0438	transferase activity, transferring glycosyl groups
ICG51_RS08750	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ICG51_RS08765	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ICG51_RS08790	COG2086	electron transfer activity
ICG51_RS08815	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ICG51_RS08815	COG3218	ABC-type transport auxiliary lipoprotein component
ICG51_RS08820	COG1127	ABC transporter
ICG51_RS08825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ICG51_RS08840	COG0442	prolyl-tRNA aminoacylation
ICG51_RS08855	COG1183	phosphatidylcholine synthase activity
ICG51_RS08870	COG0720	synthase
ICG51_RS08875	COG2906	2 iron, 2 sulfur cluster binding
ICG51_RS08950	COG1902	pentaerythritol trinitrate reductase activity
ICG51_RS08955	COG3384	dioxygenase
ICG51_RS08965	COG4181	ATPase activity
ICG51_RS08975	COG0151	Belongs to the GarS family
ICG51_RS08980	COG0138	bifunctional purine biosynthesis protein purh
ICG51_RS08985	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ICG51_RS08995	COG2264	protein methyltransferase activity
ICG51_RS09005	COG0439	Biotin carboxylase
ICG51_RS09010	COG0511	ligase activity, forming carbon-carbon bonds
ICG51_RS09015	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ICG51_RS09020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ICG51_RS09030	COG1324	tolerance protein
ICG51_RS09055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICG51_RS09060	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ICG51_RS09070	COG0778	Nitroreductase
ICG51_RS09075	COG2353	YceI-like domain
ICG51_RS09080	COG1741	Belongs to the pirin family
ICG51_RS09090	COG0297	glycogen (starch) synthase activity
ICG51_RS09100	COG1560	Kdo2-lipid A biosynthetic process
ICG51_RS09105	COG1519	Transferase
ICG51_RS09110	COG1538	Outer membrane efflux protein
ICG51_RS09115	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ICG51_RS09135	COG3300	MHYT domain
ICG51_RS09135	COG5001	Diguanylate cyclase
ICG51_RS09145	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ICG51_RS09150	COG0066	3-isopropylmalate dehydratase activity
ICG51_RS09155	COG0473	3-isopropylmalate dehydrogenase activity
ICG51_RS09160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ICG51_RS09180	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ICG51_RS09185	COG0129	dihydroxy-acid dehydratase activity
ICG51_RS09200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ICG51_RS09225	COG3079	Belongs to the UPF0149 family
ICG51_RS09230	COG0006	proline dipeptidase activity
ICG51_RS09235	COG0006	proline dipeptidase activity
ICG51_RS09250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ICG51_RS09255	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ICG51_RS09260	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ICG51_RS09265	COG1561	YicC-like family, N-terminal region
ICG51_RS09270	COG0194	GDP metabolic process
ICG51_RS09275	COG1758	RNA polymerase activity
ICG51_RS09280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ICG51_RS09290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICG51_RS09310	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ICG51_RS09330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICG51_RS09340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ICG51_RS09340	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ICG51_RS09400	COG0789	Transcriptional regulator
ICG51_RS09435	COG0640	Transcriptional regulator
ICG51_RS09440	COG0446	pyridine nucleotide-disulphide oxidoreductase
ICG51_RS09445	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ICG51_RS09490	COG0254	rRNA binding
ICG51_RS09495	COG0372	Belongs to the citrate synthase family
ICG51_RS09505	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ICG51_RS09535	COG0714	Associated with various cellular activities
ICG51_RS09565	COG1301	dicarboxylic acid transport
ICG51_RS09570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ICG51_RS09590	COG3682	Transcriptional regulator
ICG51_RS09610	COG3047	cAMP biosynthetic process
ICG51_RS09615	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ICG51_RS09620	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ICG51_RS09650	COG0126	phosphoglycerate kinase activity
ICG51_RS09660	COG0469	pyruvate kinase activity
ICG51_RS09670	COG3588	fructose-bisphosphate aldolase
ICG51_RS09685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ICG51_RS09725	COG3275	phosphorelay sensor kinase activity
ICG51_RS09730	COG1793	dna ligase
ICG51_RS09735	COG3795	YCII-related domain
ICG51_RS09740	COG3795	YCII-related domain
ICG51_RS09745	COG2764	glyoxalase bleomycin resistance protein dioxygenase
ICG51_RS09755	COG4941	Belongs to the sigma-70 factor family
ICG51_RS09785	COG2813	Specifically methylates the guanine in position
ICG51_RS09790	COG1187	pseudouridine synthase activity
ICG51_RS09800	COG1666	GTP binding
ICG51_RS09805	COG0697	spore germination
ICG51_RS09810	COG0508	dehydrogenase complex catalyzes the overall conversion of
ICG51_RS09815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ICG51_RS09830	COG0356	it plays a direct role in the translocation of protons across the membrane
ICG51_RS09840	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ICG51_RS09845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ICG51_RS09850	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ICG51_RS09855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ICG51_RS09860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ICG51_RS09865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ICG51_RS09880	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ICG51_RS09890	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ICG51_RS09895	COG0564	pseudouridine synthase activity
ICG51_RS09920	COG0542	response to heat
ICG51_RS09925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ICG51_RS09925	COG4651	solute:proton antiporter activity
ICG51_RS09935	COG0488	(ABC) transporter
ICG51_RS09950	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ICG51_RS09970	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ICG51_RS09975	COG0632	four-way junction helicase activity
ICG51_RS09985	COG5001	Diguanylate cyclase
ICG51_RS09990	COG2255	four-way junction helicase activity
ICG51_RS09995	COG0824	Thioesterase
ICG51_RS10005	COG0848	biopolymer transport protein
ICG51_RS10020	COG2885	chlorophyll binding
ICG51_RS10030	COG0602	queuosine metabolic process
ICG51_RS10035	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ICG51_RS10045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ICG51_RS10050	COG2211	Major facilitator Superfamily
ICG51_RS10060	COG0330	HflC and HflK could
ICG51_RS10090	COG1704	LemA family
ICG51_RS10095	COG0501	Belongs to the peptidase M48B family
ICG51_RS10115	COG1960	acyl-CoA dehydrogenase activity
ICG51_RS10120	COG1309	transcriptional regulator
ICG51_RS10125	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ICG51_RS10135	COG0457	Tetratricopeptide repeat
ICG51_RS10170	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ICG51_RS10180	COG0463	Glycosyl transferase, family 2
ICG51_RS10185	COG0617	tRNA 3'-terminal CCA addition
ICG51_RS10185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ICG51_RS10185	COG3620	sequence-specific DNA binding
ICG51_RS10200	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ICG51_RS10210	COG0739	heme binding
ICG51_RS10215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ICG51_RS10220	COG0626	cystathionine gamma-synthase activity
ICG51_RS10225	COG0527	aspartate kinase activity
ICG51_RS10225	COG0460	homoserine dehydrogenase
ICG51_RS10230	COG5002	protein histidine kinase activity
ICG51_RS10230	COG5001	Diguanylate cyclase
ICG51_RS10235	COG3706	GGDEF domain
ICG51_RS10240	COG1760	l-serine dehydratase
ICG51_RS10255	COG3038	cytochrome b561
ICG51_RS10265	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ICG51_RS10290	COG0259	pyridoxamine-phosphate oxidase activity
ICG51_RS10295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ICG51_RS10310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ICG51_RS10325	COG1678	Uncharacterized ACR, COG1678
ICG51_RS10330	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ICG51_RS10335	COG0540	Belongs to the ATCase OTCase family
ICG51_RS10345	COG2239	Acts as a magnesium transporter
ICG51_RS10350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ICG51_RS10385	COG1137	ATPase activity
ICG51_RS10390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ICG51_RS10400	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ICG51_RS10410	COG0271	Belongs to the BolA IbaG family
ICG51_RS10415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ICG51_RS10470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ICG51_RS10480	COG2354	Protein conserved in bacteria
ICG51_RS10485	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ICG51_RS10490	COG0745	RESPONSE REGULATOR receiver
ICG51_RS10495	COG2205	protein histidine kinase activity
ICG51_RS10500	COG4452	Inner membrane protein CreD
ICG51_RS10515	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ICG51_RS10540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ICG51_RS10545	COG0473	3-isopropylmalate dehydrogenase activity
ICG51_RS10580	COG0544	peptidyl-prolyl cis-trans isomerase activity
ICG51_RS10590	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ICG51_RS10615	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICG51_RS10625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ICG51_RS10640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICG51_RS10645	COG0631	protein serine/threonine phosphatase activity
ICG51_RS10660	COG0859	PFAM glycosyl transferase family 9
ICG51_RS10665	COG3642	lipopolysaccharide core region biosynthetic process
ICG51_RS10695	COG0537	adenosine 5'-monophosphoramidase activity
ICG51_RS10715	COG0714	Associated with various cellular activities
ICG51_RS10740	COG1399	metal-binding, possibly nucleic acid-binding protein
ICG51_RS10745	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ICG51_RS10750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ICG51_RS10755	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ICG51_RS10775	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ICG51_RS10780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ICG51_RS10785	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ICG51_RS10790	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ICG51_RS10805	COG1725	Transcriptional regulator
ICG51_RS10810	COG1131	(ABC) transporter
ICG51_RS10830	COG1250	3-hydroxyacyl-CoA dehydrogenase
ICG51_RS10830	COG1024	Enoyl-CoA hydratase
ICG51_RS10845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ICG51_RS10850	COG0481	GTPase activity
ICG51_RS10855	COG0681	Belongs to the peptidase S26 family
ICG51_RS10870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ICG51_RS10875	COG1381	Involved in DNA repair and RecF pathway recombination
ICG51_RS10880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ICG51_RS10890	COG1534	Rna-binding protein
ICG51_RS10895	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ICG51_RS10900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ICG51_RS10905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ICG51_RS10910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ICG51_RS10915	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ICG51_RS10920	COG1923	regulation of RNA biosynthetic process
ICG51_RS10925	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ICG51_RS10930	COG0330	HflC and HflK could
ICG51_RS10935	COG0330	HflC and HflK could
ICG51_RS10955	COG1272	protein, Hemolysin III
ICG51_RS10960	COG0308	aminopeptidase N
ICG51_RS10975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ICG51_RS10980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICG51_RS10985	COG4206	TonB-dependent receptor
ICG51_RS10990	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICG51_RS10990	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ICG51_RS10995	COG2814	Major facilitator Superfamily
ICG51_RS11000	COG0531	amino acid
ICG51_RS11025	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ICG51_RS11030	COG2894	cell division
ICG51_RS11035	COG0850	regulation of cytokinetic process
ICG51_RS11045	COG4585	Histidine kinase
ICG51_RS11050	COG2197	response regulator
ICG51_RS11065	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ICG51_RS11090	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ICG51_RS11100	COG4974	Belongs to the 'phage' integrase family
ICG51_RS11200	COG0515	serine threonine protein kinase
ICG51_RS11200	COG2815	serine threonine protein kinase
ICG51_RS11210	COG3118	belongs to the thioredoxin family
ICG51_RS11235	COG4095	Psort location CytoplasmicMembrane, score
ICG51_RS11275	COG0495	leucyl-tRNA aminoacylation
ICG51_RS11290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ICG51_RS11315	COG0052	Belongs to the universal ribosomal protein uS2 family
ICG51_RS11320	COG0024	Methionine aminopeptidase
ICG51_RS11340	COG1393	Belongs to the ArsC family
ICG51_RS11345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ICG51_RS11350	COG0367	asparagine synthase
ICG51_RS11390	COG2010	Cytochrome c
ICG51_RS11405	COG3278	Belongs to the heme-copper respiratory oxidase family
ICG51_RS11410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICG51_RS11425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ICG51_RS11455	COG3154	lipid carrier protein
ICG51_RS11465	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ICG51_RS11470	COG0826	peptidase U32
ICG51_RS11475	COG0826	peptidase U32
ICG51_RS11485	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ICG51_RS11490	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ICG51_RS11515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ICG51_RS11520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ICG51_RS11525	COG0500	methyltransferase
ICG51_RS11540	COG2885	chlorophyll binding
ICG51_RS11550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ICG51_RS11555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ICG51_RS11555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ICG51_RS11560	COG0802	atpase or kinase
ICG51_RS11585	COG2878	Part of a membrane complex involved in electron transport
ICG51_RS11595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICG51_RS11595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ICG51_RS11615	COG4771	TonB-dependent receptor
ICG51_RS11625	COG4771	TonB-dependent receptor
ICG51_RS11630	COG0489	protein tyrosine kinase activity
ICG51_RS11635	COG0717	Belongs to the dCTP deaminase family
ICG51_RS11645	COG0412	Dienelactone hydrolase
ICG51_RS11660	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ICG51_RS11665	COG0612	Peptidase, M16
ICG51_RS11705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ICG51_RS11710	COG0719	Fe-S assembly protein
ICG51_RS11715	COG0396	ATPase activity
ICG51_RS11720	COG0719	Fe-S assembly protein
ICG51_RS11795	COG0457	Tetratricopeptide repeat
ICG51_RS11800	COG4771	TonB-dependent receptor
ICG51_RS11830	COG1981	membrane
ICG51_RS11840	COG1301	dicarboxylic acid transport
ICG51_RS11855	COG1877	trehalose-phosphatase activity
ICG51_RS11860	COG3387	PFAM Glycoside hydrolase 15-related
ICG51_RS11865	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ICG51_RS11880	COG0516	GMP reductase activity
ICG51_RS11880	COG0517	IMP dehydrogenase activity
ICG51_RS11930	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_RS11950	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ICG51_RS11965	COG0587	DNA-directed DNA polymerase activity
ICG51_RS11975	COG0557	exoribonuclease II activity
ICG51_RS11980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ICG51_RS11990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ICG51_RS12010	COG0704	Plays a role in the regulation of phosphate uptake
ICG51_RS12030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ICG51_RS12045	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ICG51_RS12055	COG1024	Enoyl-CoA hydratase
ICG51_RS12070	COG0494	nUDIX hydrolase
ICG51_RS12090	COG0824	Thioesterase
ICG51_RS12095	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ICG51_RS12110	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ICG51_RS12115	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ICG51_RS12130	COG0196	riboflavin kinase activity
ICG51_RS12145	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ICG51_RS12155	COG0582	viral genome integration into host DNA
ICG51_RS12220	COG2814	Major facilitator Superfamily
ICG51_RS12225	COG1566	PFAM secretion protein HlyD family protein
ICG51_RS12235	COG1846	Transcriptional regulator
ICG51_RS12240	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ICG51_RS12255	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ICG51_RS12260	COG0521	Mo-molybdopterin cofactor biosynthetic process
ICG51_RS12260	COG0315	cyclic pyranopterin monophosphate synthase activity
ICG51_RS12265	COG0303	'Molybdopterin
ICG51_RS12275	COG0314	molybdopterin synthase activity
ICG51_RS12285	COG2223	nitrite transmembrane transporter activity
ICG51_RS12290	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ICG51_RS12295	COG1140	nitrate reductase beta subunit
ICG51_RS12300	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
ICG51_RS12305	COG2181	nitrate reductase activity
ICG51_RS12310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ICG51_RS12325	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ICG51_RS12340	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ICG51_RS12345	COG4269	membrane
ICG51_RS12355	COG0228	four-way junction DNA binding
ICG51_RS12360	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ICG51_RS12365	COG0336	Belongs to the RNA methyltransferase TrmD family
ICG51_RS12385	COG0625	glutathione transferase activity
ICG51_RS12390	COG3773	Cell wall hydrolase
ICG51_RS12390	COG3409	Peptidoglycan-binding domain 1 protein
ICG51_RS12400	COG1522	sequence-specific DNA binding
ICG51_RS12405	COG0626	cystathionine gamma-synthase activity
ICG51_RS12420	COG0753	catalase activity
ICG51_RS12425	COG2258	MOSC domain
ICG51_RS12450	COG1546	Belongs to the CinA family
ICG51_RS12460	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ICG51_RS12465	COG2137	regulation of response to DNA damage stimulus
ICG51_RS12470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ICG51_RS12475	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ICG51_RS12505	COG0784	Response regulator, receiver
ICG51_RS12505	COG5002	protein histidine kinase activity
ICG51_RS12505	COG2205	protein histidine kinase activity
ICG51_RS12560	COG0366	Alpha amylase catalytic
ICG51_RS12565	COG1082	Xylose isomerase domain protein TIM barrel
ICG51_RS12575	COG0800	Aldolase
ICG51_RS12595	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ICG51_RS12615	COG0659	secondary active sulfate transmembrane transporter activity
ICG51_RS12620	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ICG51_RS12625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ICG51_RS12635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ICG51_RS12645	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ICG51_RS12655	COG2166	iron-sulfur cluster assembly
ICG51_RS12670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ICG51_RS12675	COG0137	argininosuccinate synthase activity
ICG51_RS12680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ICG51_RS12685	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ICG51_RS12690	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ICG51_RS12695	COG0165	Argininosuccinate lyase
ICG51_RS12705	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ICG51_RS12840	COG4797	methyltransferase
ICG51_RS12840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ICG51_RS12845	COG2205	protein histidine kinase activity
ICG51_RS12855	COG0124	histidyl-tRNA synthetase
ICG51_RS12860	COG2986	histidine ammonia-lyase
ICG51_RS12880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ICG51_RS12885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICG51_RS12890	COG0131	Imidazoleglycerol-phosphate dehydratase
ICG51_RS12890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ICG51_RS12895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ICG51_RS12910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ICG51_RS12910	COG0140	phosphoribosyl-ATP diphosphatase activity
ICG51_RS12930	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ICG51_RS12935	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ICG51_RS12940	COG0235	Class ii aldolase
ICG51_RS12945	COG0235	Class ii aldolase
ICG51_RS12950	COG0531	amino acid
ICG51_RS12960	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ICG51_RS12965	COG0277	FAD linked oxidase domain protein
ICG51_RS13000	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ICG51_RS13035	COG1024	Enoyl-CoA hydratase
ICG51_RS13070	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ICG51_RS13075	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ICG51_RS13080	COG2954	triphosphatase activity
ICG51_RS13085	COG1472	Belongs to the glycosyl hydrolase 3 family
ICG51_RS13095	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ICG51_RS13115	COG0183	Belongs to the thiolase family
ICG51_RS13125	COG2915	High frequency lysogenization protein hflD homolog
ICG51_RS13130	COG0482	sulfurtransferase activity
ICG51_RS13145	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ICG51_RS13150	COG0542	response to heat
ICG51_RS13170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ICG51_RS13225	COG0477	Major facilitator Superfamily
ICG51_RS13235	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ICG51_RS13245	COG2610	gluconate transmembrane transporter activity
ICG51_RS13255	COG0784	Response regulator, receiver
ICG51_RS13255	COG2198	Histidine kinase
ICG51_RS13255	COG2205	protein histidine kinase activity
ICG51_RS13260	COG2197	response regulator
ICG51_RS13265	COG1530	ribonuclease E activity
ICG51_RS13275	COG2154	pterin-4-alpha-carbinolamine dehydratase
ICG51_RS13280	COG0316	Belongs to the HesB IscA family
ICG51_RS13280	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ICG51_RS13300	COG0017	Asparaginyl-tRNA synthetase
ICG51_RS13305	COG0316	Belongs to the HesB IscA family
ICG51_RS13310	COG0360	Binds together with S18 to 16S ribosomal RNA
ICG51_RS13315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ICG51_RS13320	COG0359	binds to the 23S rRNA
ICG51_RS13325	COG0305	Participates in initiation and elongation during chromosome replication
ICG51_RS13330	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ICG51_RS13340	COG2885	chlorophyll binding
ICG51_RS13355	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ICG51_RS13380	COG1028	Short-chain dehydrogenase reductase Sdr
ICG51_RS13390	COG0501	Belongs to the peptidase M48B family
ICG51_RS13395	COG5002	protein histidine kinase activity
ICG51_RS13395	COG5001	Diguanylate cyclase
ICG51_RS13400	COG1509	lysine 2,3-aminomutase activity
ICG51_RS13410	COG0402	S-adenosylhomocysteine deaminase activity
ICG51_RS13430	COG1469	GTP cyclohydrolase I activity
ICG51_RS13440	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ICG51_RS13455	COG0339	signal peptide processing
ICG51_RS13460	COG0386	Belongs to the glutathione peroxidase family
ICG51_RS13485	COG2133	pyrroloquinoline quinone binding
ICG51_RS13510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ICG51_RS13515	COG0084	hydrolase, TatD family'
ICG51_RS13525	COG3134	Outer membrane lipoprotein
ICG51_RS13530	COG1960	acyl-CoA dehydrogenase activity
ICG51_RS13540	COG0625	glutathione transferase activity
ICG51_RS13545	COG0022	dehydrogenase e1 component
ICG51_RS13550	COG0028	Belongs to the TPP enzyme family
ICG51_RS13575	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ICG51_RS13580	COG1053	succinate dehydrogenase
ICG51_RS13600	COG4591	ABC-type transport system involved in lipoprotein release permease component
ICG51_RS13610	COG0658	competence protein
ICG51_RS13610	COG2333	competence protein COMEC
ICG51_RS13615	COG0811	peptide transport
ICG51_RS13630	COG1663	tetraacyldisaccharide 4'-kinase activity
ICG51_RS13635	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ICG51_RS13640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ICG51_RS13645	COG0322	excinuclease ABC activity
ICG51_RS13650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ICG51_RS13695	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ICG51_RS13705	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ICG51_RS13710	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ICG51_RS13730	COG1131	(ABC) transporter
ICG51_RS13735	COG1725	Transcriptional regulator
ICG51_RS13745	COG0545	Peptidyl-prolyl cis-trans isomerase
ICG51_RS13760	COG2900	Belongs to the SlyX family
ICG51_RS13770	COG1410	methionine synthase
ICG51_RS13770	COG0646	methionine synthase
ICG51_RS13785	COG1960	acyl-CoA dehydrogenase activity
ICG51_RS13790	COG2902	Dehydrogenase
ICG51_RS13800	COG5002	protein histidine kinase activity
ICG51_RS13800	COG5001	Diguanylate cyclase
ICG51_RS13815	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ICG51_RS13820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ICG51_RS13835	COG0438	transferase activity, transferring glycosyl groups
ICG51_RS13850	COG0438	transferase activity, transferring glycosyl groups
ICG51_RS13865	COG0438	transferase activity, transferring glycosyl groups
ICG51_RS13870	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ICG51_RS13900	COG0318	PFAM AMP-dependent synthetase and ligase
ICG51_RS13915	COG3706	GGDEF domain
ICG51_RS13935	COG2409	Drug exporters of the RND superfamily
ICG51_RS13945	COG0745	RESPONSE REGULATOR receiver
ICG51_RS13955	COG0835	chemotaxis
ICG51_RS13960	COG1192	Involved in chromosome partitioning
ICG51_RS13965	COG1360	Flagellar Motor Protein
ICG51_RS13970	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ICG51_RS13975	COG2198	Histidine kinase
ICG51_RS13975	COG0643	Histidine kinase
ICG51_RS13975	COG0784	Response regulator, receiver
ICG51_RS13980	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ICG51_RS14020	COG1987	bacterial-type flagellum assembly
ICG51_RS14050	COG3144	bacterial-type flagellum assembly
ICG51_RS14080	COG1677	Flagellar hook-basal body complex protein FliE
ICG51_RS14090	COG2201	protein-glutamate methylesterase activity
ICG51_RS14165	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ICG51_RS14170	COG4786	Flagellar basal body rod
ICG51_RS14175	COG4787	bacterial-type flagellum-dependent cell motility
ICG51_RS14180	COG1749	Flagellar hook protein flgE
ICG51_RS14190	COG1558	bacterial-type flagellum-dependent cell motility
ICG51_RS14195	COG1815	bacterial-type flagellum-dependent cell motility
ICG51_RS14200	COG0784	Response regulator, receiver
ICG51_RS14200	COG0835	chemotaxis
ICG51_RS14240	COG3384	dioxygenase