locus-tag	class	description
TALC_RS00025	COG1269	ATP hydrolysis coupled proton transport
TALC_RS00050	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TALC_RS00055	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TALC_RS00060	COG1394	ATPase activity, coupled to movement of substances
TALC_RS00105	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TALC_RS00115	COG1131	(ABC) transporter
TALC_RS00125	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TALC_RS00160	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TALC_RS00165	COG0519	Catalyzes the synthesis of GMP from XMP
TALC_RS00165	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TALC_RS00170	COG1846	Transcriptional regulator
TALC_RS00175	COG0519	Catalyzes the synthesis of GMP from XMP
TALC_RS00195	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TALC_RS00225	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
TALC_RS00255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TALC_RS00260	COG0281	malic enzyme
TALC_RS00290	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
TALC_RS00305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TALC_RS00315	COG0463	Glycosyl transferase, family 2
TALC_RS00355	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TALC_RS00375	COG3475	LICD family
TALC_RS00380	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TALC_RS00385	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
TALC_RS00385	COG0028	Belongs to the TPP enzyme family
TALC_RS00390	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TALC_RS00390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TALC_RS00400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TALC_RS00435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TALC_RS00440	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TALC_RS00450	COG0028	Belongs to the TPP enzyme family
TALC_RS00460	COG0546	phosphoglycolate phosphatase activity
TALC_RS00465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TALC_RS00470	COG0463	Glycosyl transferase, family 2
TALC_RS00480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TALC_RS00490	COG1215	transferase activity, transferring glycosyl groups
TALC_RS00500	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TALC_RS00540	COG0105	UTP biosynthetic process
TALC_RS00545	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TALC_RS00575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TALC_RS00585	COG0287	Prephenate dehydrogenase
TALC_RS00600	COG0477	Major facilitator Superfamily
TALC_RS00650	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TALC_RS00650	COG0617	tRNA 3'-terminal CCA addition
TALC_RS00650	COG0517	IMP dehydrogenase activity
TALC_RS00665	COG1872	DUF167
TALC_RS00675	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TALC_RS00695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TALC_RS00700	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TALC_RS00715	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TALC_RS00720	COG0047	phosphoribosylformylglycinamidine synthase activity
TALC_RS00770	COG1120	ATPase activity
TALC_RS00775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TALC_RS00800	COG0052	Belongs to the universal ribosomal protein uS2 family
TALC_RS00805	COG1355	regulation of microtubule-based process
TALC_RS00830	COG0436	Aminotransferase
TALC_RS00840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TALC_RS00850	COG1199	ATP-dependent helicase activity
TALC_RS00880	COG0138	bifunctional purine biosynthesis protein purh
TALC_RS00920	COG3959	Transketolase, thiamine diphosphate binding domain
TALC_RS00925	COG3958	Transketolase
TALC_RS00930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TALC_RS00940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TALC_RS00950	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TALC_RS00955	COG1850	ribulose-bisphosphate carboxylase activity
TALC_RS00970	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TALC_RS00985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TALC_RS00995	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TALC_RS01000	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TALC_RS01005	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TALC_RS01010	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TALC_RS01025	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TALC_RS01040	COG0713	ATP synthesis coupled electron transport
TALC_RS01045	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TALC_RS01055	COG1007	ATP synthesis coupled electron transport
TALC_RS01065	COG0142	geranyltranstransferase activity
TALC_RS01085	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TALC_RS01090	COG1573	uracil-dna glycosylase
TALC_RS01095	COG0647	UMP catabolic process
TALC_RS01115	COG1196	nuclear chromosome segregation
TALC_RS01135	COG3842	ATPase activity
TALC_RS01140	COG3842	ATPase activity
TALC_RS01150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TALC_RS01160	COG0010	Belongs to the arginase family
TALC_RS01175	COG0235	Class ii aldolase
TALC_RS01190	COG0430	RNA-3'-phosphate cyclase activity
TALC_RS01210	COG0433	COG0433 Predicted ATPase
TALC_RS01220	COG1012	belongs to the aldehyde dehydrogenase family
TALC_RS01275	COG1691	(AIR) carboxylase
TALC_RS01310	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TALC_RS01315	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TALC_RS01315	COG0116	Belongs to the methyltransferase superfamily
TALC_RS01345	COG0402	S-adenosylhomocysteine deaminase activity
TALC_RS01355	COG1918	ferrous iron import across plasma membrane
TALC_RS01355	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TALC_RS01370	COG1309	transcriptional regulator
TALC_RS01390	COG1971	Probably functions as a manganese efflux pump
TALC_RS01440	COG5012	cobalamin binding
TALC_RS01480	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TALC_RS01490	COG2217	Heavy metal translocating P-type atpase
TALC_RS01525	COG0477	Major facilitator Superfamily
TALC_RS01540	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TALC_RS01545	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TALC_RS01575	COG1185	polyribonucleotide nucleotidyltransferase activity
TALC_RS01585	COG0539	negative regulation of cytoplasmic translation
TALC_RS01620	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TALC_RS01625	COG3259	Nickel-dependent hydrogenase
TALC_RS01635	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TALC_RS01635	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TALC_RS01675	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TALC_RS01675	COG0674	pyruvate-flavodoxin oxidoreductase activity
TALC_RS01690	COG1426	Protein conserved in bacteria
TALC_RS01695	COG0318	PFAM AMP-dependent synthetase and ligase
TALC_RS01705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TALC_RS01855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TALC_RS01875	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TALC_RS01880	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TALC_RS01885	COG0051	transcription antitermination factor activity, RNA binding
TALC_RS01905	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TALC_RS02020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TALC_RS02040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TALC_RS02050	COG0024	Methionine aminopeptidase
TALC_RS02065	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TALC_RS02070	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TALC_RS02075	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TALC_RS02090	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TALC_RS02125	COG0436	Aminotransferase
TALC_RS02140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TALC_RS02145	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TALC_RS02180	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
TALC_RS02185	COG0602	queuosine metabolic process
TALC_RS02195	COG0489	protein tyrosine kinase activity
TALC_RS02215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TALC_RS02235	COG1078	dGTPase activity
TALC_RS02265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TALC_RS02325	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TALC_RS02370	COG0247	lactate metabolic process
TALC_RS02370	COG0277	FAD linked oxidase domain protein
TALC_RS02385	COG0546	phosphoglycolate phosphatase activity
TALC_RS02405	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TALC_RS02410	COG2076	Multidrug Resistance protein
TALC_RS02420	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TALC_RS02435	COG1185	polyribonucleotide nucleotidyltransferase activity
TALC_RS02475	COG0084	hydrolase, TatD family'
TALC_RS02480	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TALC_RS02505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TALC_RS02515	COG1234	tRNA 3'-trailer cleavage
TALC_RS02525	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
TALC_RS02580	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TALC_RS02600	COG1454	alcohol dehydrogenase
TALC_RS02610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TALC_RS02610	COG0140	phosphoribosyl-ATP diphosphatase activity
TALC_RS02615	COG0107	imidazoleglycerol-phosphate synthase activity
TALC_RS02620	COG0131	Imidazoleglycerol-phosphate dehydratase
TALC_RS02640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TALC_RS02645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TALC_RS02650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TALC_RS02655	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TALC_RS02660	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TALC_RS02675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TALC_RS02690	COG1830	Aldolase
TALC_RS02695	COG1465	3-dehydroquinate synthase
TALC_RS02700	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TALC_RS02710	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TALC_RS02715	COG0352	thiamine-phosphate diphosphorylase activity
TALC_RS02725	COG2022	thiamine diphosphate biosynthetic process
TALC_RS02745	COG0488	(ABC) transporter
TALC_RS02750	COG0473	3-isopropylmalate dehydrogenase activity
TALC_RS02770	COG0655	NAD(P)H dehydrogenase (quinone) activity
TALC_RS02820	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TALC_RS02830	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TALC_RS02835	COG2326	polyphosphate kinase activity
TALC_RS02870	COG0083	homoserine kinase activity
TALC_RS02885	COG4581	dead DEAH box helicase
TALC_RS02900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TALC_RS02905	COG1546	Belongs to the CinA family
TALC_RS02905	COG1058	Belongs to the CinA family
TALC_RS02910	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TALC_RS02925	COG0371	Dehydrogenase
TALC_RS02945	COG2033	superoxide reductase activity
TALC_RS02955	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TALC_RS02985	COG0352	thiamine-phosphate diphosphorylase activity
TALC_RS02990	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
TALC_RS03000	COG0351	phosphomethylpyrimidine kinase
TALC_RS03010	COG2873	o-acetylhomoserine
TALC_RS03015	COG0165	Argininosuccinate lyase
TALC_RS03020	COG0137	argininosuccinate synthase activity
TALC_RS03025	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TALC_RS03030	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TALC_RS03035	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TALC_RS03040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TALC_RS03070	COG0477	Major facilitator Superfamily
TALC_RS03115	COG0641	radical SAM
TALC_RS03120	COG0251	oxidation-reduction process
TALC_RS03125	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
TALC_RS03130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TALC_RS03140	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TALC_RS03150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TALC_RS03165	COG3845	ABC transporter
TALC_RS03175	COG0534	Mate efflux family protein
TALC_RS03180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TALC_RS03195	COG1373	ATPase (AAA superfamily
TALC_RS03210	COG1830	Aldolase
TALC_RS03240	COG0606	chelatase, subunit chli
TALC_RS03245	COG0358	DNA primase activity
TALC_RS03250	COG4717	serine-type aminopeptidase activity
TALC_RS03255	COG0420	3'-5' exonuclease activity
TALC_RS03265	COG1980	fructose-bisphosphate aldolase activity
TALC_RS03270	COG0017	Asparaginyl-tRNA synthetase
TALC_RS03280	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TALC_RS03290	COG1618	nucleotide phosphatase activity, acting on free nucleotides
TALC_RS03295	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
TALC_RS03305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TALC_RS03325	COG2409	Drug exporters of the RND superfamily
TALC_RS03330	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TALC_RS03345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TALC_RS03365	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TALC_RS03365	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TALC_RS03370	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TALC_RS03370	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TALC_RS03380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TALC_RS03390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TALC_RS03395	COG0668	transmembrane transport
TALC_RS03410	COG0436	Aminotransferase
TALC_RS03420	COG1045	serine acetyltransferase
TALC_RS03425	COG0215	cysteine-tRNA ligase activity
TALC_RS03430	COG0037	tRNA processing
TALC_RS03445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TALC_RS03475	COG2759	Belongs to the formate--tetrahydrofolate ligase family
TALC_RS03480	COG0546	phosphoglycolate phosphatase activity
TALC_RS03490	COG0640	Transcriptional regulator
TALC_RS03495	COG2217	Heavy metal translocating P-type atpase
TALC_RS03500	COG0443	Heat shock 70 kDa protein
TALC_RS03520	COG0443	Heat shock 70 kDa protein
TALC_RS03525	COG1187	pseudouridine synthase activity
TALC_RS03535	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TALC_RS03590	COG2252	PERMEase
TALC_RS03600	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TALC_RS03605	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TALC_RS03610	COG0248	Ppx GppA phosphatase
TALC_RS03625	COG3848	Pyruvate phosphate dikinase
TALC_RS03625	COG0574	Belongs to the PEP-utilizing enzyme family
TALC_RS03640	COG0459	protein refolding
TALC_RS03650	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TALC_RS03665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
TALC_RS03670	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
TALC_RS03680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TALC_RS03685	COG2814	Major facilitator Superfamily
TALC_RS03690	COG2267	carboxylic ester hydrolase activity
TALC_RS03695	COG0644	oxidoreductase
TALC_RS03730	COG0667	Aldo Keto reductase
TALC_RS03735	COG1032	radical SAM domain protein
TALC_RS03760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TALC_RS03760	COG1199	ATP-dependent helicase activity
TALC_RS03810	COG3693	PFAM glycoside hydrolase, family 10
TALC_RS03865	COG1489	DNA binding
TALC_RS03975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TALC_RS03980	COG1120	ATPase activity
TALC_RS04250	COG1119	ATPase activity
TALC_RS04260	COG0426	domain, Protein
TALC_RS04260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TALC_RS04275	COG0534	Mate efflux family protein
TALC_RS04280	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
TALC_RS04285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TALC_RS04355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TALC_RS04385	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TALC_RS04395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TALC_RS04415	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
TALC_RS04435	COG1132	(ABC) transporter
TALC_RS04440	COG1132	(ABC) transporter
TALC_RS04450	COG3422	double-strand break repair
TALC_RS04525	COG1115	amino acid carrier protein
TALC_RS04545	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
TALC_RS04550	COG0523	cobalamin synthesis protein
TALC_RS04560	COG5377	YqaJ viral recombinase family
TALC_RS04565	COG0300	oxidoreductase activity
TALC_RS04575	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
TALC_RS04585	COG0135	phosphoribosylanthranilate isomerase activity
TALC_RS04595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TALC_RS04605	COG0495	leucyl-tRNA aminoacylation
TALC_RS04620	COG0163	prenyltransferase activity
TALC_RS04625	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TALC_RS04630	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TALC_RS04655	COG1966	Carbon starvation protein
TALC_RS04660	COG0826	peptidase U32
TALC_RS04685	COG2226	methyltransferase
TALC_RS04690	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TALC_RS04730	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TALC_RS04740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TALC_RS04750	COG0347	Belongs to the P(II) protein family
TALC_RS04755	COG0004	ammonium transporteR
TALC_RS04775	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TALC_RS04780	COG0519	Catalyzes the synthesis of GMP from XMP
TALC_RS04800	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
TALC_RS04845	COG0543	2 iron, 2 sulfur cluster binding
TALC_RS04850	COG0167	dihydroorotate dehydrogenase activity
TALC_RS04860	COG0569	domain protein
TALC_RS04865	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TALC_RS04915	COG1722	exodeoxyribonuclease VII activity
TALC_RS04920	COG1570	exodeoxyribonuclease VII activity
TALC_RS04960	COG1074	ATP-dependent DNA helicase activity
TALC_RS04975	COG1131	(ABC) transporter
TALC_RS04985	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TALC_RS05000	COG1492	cobalamin metabolic process
TALC_RS05045	COG1253	flavin adenine dinucleotide binding
TALC_RS05050	COG4443	Transcriptional Coactivator p15 (PC4)
TALC_RS05095	COG0492	ferredoxin-NADP+ reductase activity
TALC_RS05110	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TALC_RS05120	COG0589	response to stress
TALC_RS05125	COG0589	response to stress
TALC_RS05130	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TALC_RS05130	COG0517	IMP dehydrogenase activity
TALC_RS05130	COG0617	tRNA 3'-terminal CCA addition
TALC_RS05145	COG0525	valine-tRNA ligase activity
TALC_RS05150	COG1773	rubredoxin
TALC_RS05165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TALC_RS05225	COG5012	cobalamin binding
TALC_RS05250	COG5012	cobalamin binding
TALC_RS05275	COG5012	cobalamin binding
TALC_RS05285	COG1362	aminopeptidase activity
TALC_RS05310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TALC_RS05330	COG0375	protein maturation
TALC_RS05335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TALC_RS05340	COG0285	dihydrofolate synthase activity
TALC_RS05350	COG0864	Transcriptional regulator
TALC_RS05360	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TALC_RS05370	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TALC_RS05380	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TALC_RS05385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TALC_RS05390	COG0717	Belongs to the dCTP deaminase family
TALC_RS05405	COG1042	CoA-binding domain protein
TALC_RS05405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TALC_RS05405	COG0045	succinate-CoA ligase (ADP-forming) activity
TALC_RS05435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TALC_RS05440	COG4139	cobalamin transport
TALC_RS05450	COG1132	(ABC) transporter
TALC_RS05460	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
TALC_RS05485	COG1793	dna ligase
TALC_RS05495	COG0585	pseudouridine synthase activity
TALC_RS05505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TALC_RS05515	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
TALC_RS05540	COG0540	Belongs to the ATCase OTCase family
TALC_RS05545	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
TALC_RS05585	COG1013	pyruvate-flavodoxin oxidoreductase activity
TALC_RS05590	COG0674	pyruvate-flavodoxin oxidoreductase activity
TALC_RS05595	COG1144	Oxidoreductase
TALC_RS05600	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TALC_RS05605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TALC_RS05605	COG0574	Belongs to the PEP-utilizing enzyme family
TALC_RS05620	COG0517	IMP dehydrogenase activity
TALC_RS05620	COG0516	GMP reductase activity
TALC_RS05625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TALC_RS05630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TALC_RS05645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TALC_RS05670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TALC_RS05675	COG1120	ATPase activity
TALC_RS05680	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TALC_RS05725	COG1120	ATPase activity
TALC_RS05730	COG1131	(ABC) transporter
TALC_RS05775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TALC_RS05785	COG0124	histidyl-tRNA synthetase
TALC_RS05790	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TALC_RS05795	COG0113	porphobilinogen synthase activity
TALC_RS05800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TALC_RS05845	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
TALC_RS05855	COG1122	ATPase activity
TALC_RS05870	COG0310	cobalt ion transport
TALC_RS05880	COG0475	glutathione-regulated potassium exporter activity
TALC_RS05900	COG0428	transporter
TALC_RS05905	COG1797	cobyrinic acid a,c-diamide synthase activity
TALC_RS05920	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
TALC_RS05990	COG1418	mRNA catabolic process
TALC_RS05995	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TALC_RS05995	COG1648	precorrin-2 dehydrogenase activity
TALC_RS06020	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
TALC_RS06030	COG0589	response to stress
TALC_RS06040	COG0460	homoserine dehydrogenase
TALC_RS06050	COG2848	UPF0210 protein
TALC_RS06065	COG0326	Molecular chaperone. Has ATPase activity
TALC_RS06085	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TALC_RS06115	COG0003	Pfam Anion-transporting ATPase
TALC_RS06130	COG2048	Heterodisulfide reductase, subunit B
TALC_RS06150	COG0612	Peptidase, M16
TALC_RS06185	COG1994	Peptidase M50
TALC_RS06190	COG0277	FAD linked oxidase domain protein
TALC_RS06195	COG0563	adenylate kinase activity
TALC_RS06205	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TALC_RS06245	COG0018	arginyl-trna synthetase
TALC_RS06255	COG0528	UMP kinase activity
TALC_RS06310	COG0200	Binds to the 23S rRNA
TALC_RS06320	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TALC_RS06340	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TALC_RS06345	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TALC_RS06350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TALC_RS06370	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TALC_RS06375	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TALC_RS06390	COG0255	Belongs to the universal ribosomal protein uL29 family
TALC_RS06395	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TALC_RS06410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TALC_RS06415	COG0089	rRNA binding
TALC_RS06425	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TALC_RS06450	COG1469	GTP cyclohydrolase I activity
TALC_RS06455	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TALC_RS06485	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TALC_RS06490	COG0154	amidase activity
TALC_RS06495	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TALC_RS06500	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TALC_RS06510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TALC_RS06520	COG0298	carbon dioxide binding
TALC_RS06540	COG1304	FMN binding
TALC_RS06545	COG0142	geranyltranstransferase activity
TALC_RS06555	COG0515	serine threonine protein kinase
TALC_RS06560	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TALC_RS06585	COG1205	dead DEAH box helicase
TALC_RS06585	COG1111	helicase
TALC_RS06615	COG0210	DNA helicase
TALC_RS06630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TALC_RS06635	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TALC_RS06640	COG0200	Binds to the 23S rRNA
TALC_RS06650	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TALC_RS06680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TALC_RS06685	COG2181	nitrate reductase activity
TALC_RS06685	COG0247	lactate metabolic process
TALC_RS06690	COG3875	lactate racemase activity
TALC_RS06695	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
TALC_RS06700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TALC_RS06710	COG3264	Mechanosensitive ion channel
TALC_RS06710	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
TALC_RS06715	COG1522	sequence-specific DNA binding
TALC_RS06720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TALC_RS06725	COG0527	aspartate kinase activity
TALC_RS06735	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
TALC_RS06740	COG0436	Aminotransferase
TALC_RS06755	COG0126	phosphoglycerate kinase activity
TALC_RS06760	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TALC_RS06765	COG0028	Belongs to the TPP enzyme family
TALC_RS06775	COG0028	Belongs to the TPP enzyme family
TALC_RS06780	COG1151	hydroxylamine reductase activity
TALC_RS06785	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TALC_RS06795	COG0006	proline dipeptidase activity
TALC_RS06805	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
TALC_RS06840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TALC_RS06880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TALC_RS06885	COG0012	GTP binding
TALC_RS06890	COG0417	DNA replication proofreading
TALC_RS06895	COG0069	glutamate synthase activity
TALC_RS06895	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TALC_RS06905	COG0512	Glutamine amidotransferase of anthranilate synthase
TALC_RS06905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TALC_RS06915	COG0134	indole-3-glycerol-phosphate synthase activity
TALC_RS06920	COG0135	phosphoribosylanthranilate isomerase activity
TALC_RS06930	COG0159	tryptophan synthase activity
TALC_RS06945	COG0301	tRNA thio-modification
TALC_RS06950	COG0730	response to heat
TALC_RS06960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TALC_RS06975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TALC_RS06985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TALC_RS06995	COG0494	nUDIX hydrolase
TALC_RS07010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TALC_RS07035	COG1959	2 iron, 2 sulfur cluster binding
TALC_RS07045	COG2873	o-acetylhomoserine
TALC_RS07055	COG0822	iron-sulfur transferase activity
TALC_RS07065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TALC_RS07070	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TALC_RS07080	COG1373	ATPase (AAA superfamily
TALC_RS07095	COG2814	Major facilitator Superfamily
TALC_RS07120	COG0484	heat shock protein binding
TALC_RS07130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TALC_RS07135	COG0459	protein refolding
TALC_RS07220	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TALC_RS07245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TALC_RS07250	COG2813	Specifically methylates the guanine in position
TALC_RS07255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TALC_RS07275	COG0151	Belongs to the GarS family
TALC_RS07300	COG0284	orotidine-5'-phosphate decarboxylase activity
TALC_RS07325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TALC_RS07330	COG0085	RNA polymerase activity
TALC_RS07345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TALC_RS07365	COG0492	ferredoxin-NADP+ reductase activity
TALC_RS07370	COG3118	belongs to the thioredoxin family
TALC_RS07405	COG0247	lactate metabolic process
TALC_RS07410	COG1201	RNA secondary structure unwinding
TALC_RS07415	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
TALC_RS07420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TALC_RS07435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TALC_RS07440	COG0187	DNA topoisomerase II activity
TALC_RS07475	COG1201	RNA secondary structure unwinding
TALC_RS07540	COG3475	LICD family
TALC_RS07550	COG0501	Belongs to the peptidase M48B family
TALC_RS07580	COG0457	Tetratricopeptide repeat
TALC_RS07580	COG0552	protein localization to endoplasmic reticulum
TALC_RS07590	COG0183	Belongs to the thiolase family
TALC_RS07640	COG1475	DNA binding
TALC_RS07655	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TALC_RS07660	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TALC_RS07675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TALC_RS07675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TALC_RS07715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TALC_RS07750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TALC_RS07785	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
TALC_RS07800	COG0505	Belongs to the CarA family
TALC_RS07805	COG0505	Belongs to the CarA family