locus-tag	class	description
TTX_RS00020	COG0589	response to stress
TTX_RS00030	COG0154	amidase activity
TTX_RS00070	COG0051	transcription antitermination factor activity, RNA binding
TTX_RS00075	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TTX_RS00080	COG0251	oxidation-reduction process
TTX_RS00145	COG0300	oxidoreductase activity
TTX_RS00150	COG0697	spore germination
TTX_RS00190	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
TTX_RS00210	COG0693	protein deglycase activity
TTX_RS00215	COG0189	ligase activity
TTX_RS00220	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TTX_RS00250	COG0243	molybdopterin cofactor binding
TTX_RS00255	COG0437	4 iron, 4 sulfur cluster binding
TTX_RS00270	COG1234	tRNA 3'-trailer cleavage
TTX_RS00275	COG3842	ATPase activity
TTX_RS00330	COG0535	radical SAM domain protein
TTX_RS00340	COG1122	ATPase activity
TTX_RS00345	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TTX_RS00355	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTX_RS00360	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTX_RS00375	COG0243	molybdopterin cofactor binding
TTX_RS00380	COG0437	4 iron, 4 sulfur cluster binding
TTX_RS00405	COG0101	tRNA pseudouridine synthase activity
TTX_RS00420	COG0747	negative chemotaxis
TTX_RS00425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TTX_RS00430	COG0601	transmembrane transport
TTX_RS00435	COG0444	Belongs to the ABC transporter superfamily
TTX_RS00460	COG0667	Aldo Keto reductase
TTX_RS00465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TTX_RS00475	COG0537	adenosine 5'-monophosphoramidase activity
TTX_RS00490	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TTX_RS00530	COG1028	Short-chain dehydrogenase reductase Sdr
TTX_RS00540	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TTX_RS00565	COG1966	Carbon starvation protein
TTX_RS00575	COG0003	Pfam Anion-transporting ATPase
TTX_RS00580	COG0003	Pfam Anion-transporting ATPase
TTX_RS00605	COG0535	radical SAM domain protein
TTX_RS00610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TTX_RS00620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TTX_RS00625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TTX_RS00635	COG0137	argininosuccinate synthase activity
TTX_RS00650	COG0473	3-isopropylmalate dehydrogenase activity
TTX_RS00660	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TTX_RS00665	COG0066	3-isopropylmalate dehydratase activity
TTX_RS00670	COG0028	Belongs to the TPP enzyme family
TTX_RS00680	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TTX_RS00685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TTX_RS00690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TTX_RS00700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TTX_RS00705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TTX_RS00715	COG4670	ketone body catabolic process
TTX_RS00730	COG1271	oxidase subunit
TTX_RS00745	COG0450	alkyl hydroperoxide reductase
TTX_RS00800	COG4174	ABC transporter (Permease)
TTX_RS00805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TTX_RS00810	COG0444	Belongs to the ABC transporter superfamily
TTX_RS00835	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TTX_RS00850	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TTX_RS00860	COG0417	DNA replication proofreading
TTX_RS00885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TTX_RS00925	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TTX_RS00930	COG0644	oxidoreductase
TTX_RS00935	COG0235	Class ii aldolase
TTX_RS00970	COG0395	ABC-type sugar transport system, permease component
TTX_RS00975	COG3842	ATPase activity
TTX_RS00995	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
TTX_RS01000	COG1122	ATPase activity
TTX_RS01015	COG0310	cobalt ion transport
TTX_RS01020	COG0864	Transcriptional regulator
TTX_RS01030	COG0489	protein tyrosine kinase activity
TTX_RS01040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TTX_RS01055	COG0651	ATP synthesis coupled electron transport
TTX_RS01060	COG2111	Na H antiporter
TTX_RS01060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TTX_RS01065	COG1007	ATP synthesis coupled electron transport
TTX_RS01070	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TTX_RS01075	COG0674	pyruvate-flavodoxin oxidoreductase activity
TTX_RS01080	COG1013	pyruvate-flavodoxin oxidoreductase activity
TTX_RS01085	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTX_RS01100	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTX_RS01105	COG0649	NAD binding
TTX_RS01115	COG0438	transferase activity, transferring glycosyl groups
TTX_RS01125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TTX_RS01130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TTX_RS01165	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TTX_RS01180	COG1401	restriction endodeoxyribonuclease activity
TTX_RS01230	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TTX_RS01230	COG0758	DNA mediated transformation
TTX_RS01275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TTX_RS01305	COG1120	ATPase activity
TTX_RS01310	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TTX_RS01340	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TTX_RS01405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TTX_RS01425	COG0714	Associated with various cellular activities
TTX_RS01445	COG2271	Major facilitator Superfamily
TTX_RS01455	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TTX_RS01460	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
TTX_RS01465	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
TTX_RS01475	COG0602	queuosine metabolic process
TTX_RS01485	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
TTX_RS01490	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TTX_RS01505	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TTX_RS01510	COG0312	modulator of DNA gyrase
TTX_RS01515	COG0312	modulator of DNA gyrase
TTX_RS01520	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TTX_RS01530	COG0367	asparagine synthase
TTX_RS01560	COG2255	four-way junction helicase activity
TTX_RS01570	COG1881	PFAM PEBP family protein
TTX_RS01590	COG0434	BtpA family
TTX_RS01620	COG1024	Enoyl-CoA hydratase
TTX_RS01655	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
TTX_RS01675	COG1063	alcohol dehydrogenase
TTX_RS01680	COG3511	phospholipase C
TTX_RS01725	COG2890	protein-(glutamine-N5) methyltransferase activity
TTX_RS01775	COG1435	thymidine kinase activity
TTX_RS01780	COG0667	Aldo Keto reductase
TTX_RS01820	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TTX_RS01880	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TTX_RS01925	COG1131	(ABC) transporter
TTX_RS01950	COG1137	ATPase activity
TTX_RS02000	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
TTX_RS02025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TTX_RS02030	COG1254	Belongs to the acylphosphatase family
TTX_RS02035	COG0425	Belongs to the sulfur carrier protein TusA family
TTX_RS02045	COG2210	Belongs to the sulfur carrier protein TusA family
TTX_RS02065	COG0425	Belongs to the sulfur carrier protein TusA family
TTX_RS02070	COG2920	part of a sulfur-relay system
TTX_RS02110	COG2221	Nitrite and sulphite reductase 4Fe-4S
TTX_RS02115	COG2221	Nitrite and sulphite reductase 4Fe-4S
TTX_RS02125	COG2221	Nitrite and sulphite reductase 4Fe-4S
TTX_RS02185	COG2046	Belongs to the sulfate adenylyltransferase family
TTX_RS02195	COG2217	Heavy metal translocating P-type atpase
TTX_RS02250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TTX_RS02270	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TTX_RS02285	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TTX_RS02305	COG0189	ligase activity
TTX_RS02310	COG0165	Argininosuccinate lyase
TTX_RS02330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TTX_RS02335	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TTX_RS02390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TTX_RS02395	COG0667	Aldo Keto reductase
TTX_RS02410	COG1121	(ABC) transporter
TTX_RS02420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TTX_RS02435	COG0372	Belongs to the citrate synthase family
TTX_RS02475	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
TTX_RS02500	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TTX_RS02515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TTX_RS02550	COG0546	phosphoglycolate phosphatase activity
TTX_RS02605	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TTX_RS02610	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
TTX_RS02630	COG3830	Belongs to the UPF0237 family
TTX_RS02635	COG2848	UPF0210 protein
TTX_RS02650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TTX_RS02685	COG0179	Fumarylacetoacetate (FAA) hydrolase
TTX_RS02705	COG0649	NAD binding
TTX_RS02710	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TTX_RS02730	COG0651	ATP synthesis coupled electron transport
TTX_RS02735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TTX_RS02740	COG1007	ATP synthesis coupled electron transport
TTX_RS02745	COG0105	UTP biosynthetic process
TTX_RS02750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TTX_RS02775	COG1960	acyl-CoA dehydrogenase activity
TTX_RS02795	COG0243	molybdopterin cofactor binding
TTX_RS02865	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TTX_RS02880	COG0501	Belongs to the peptidase M48B family
TTX_RS02895	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TTX_RS02945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TTX_RS02955	COG1607	acyl-coa hydrolase
TTX_RS02960	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TTX_RS02995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TTX_RS02995	COG0301	tRNA thio-modification
TTX_RS03000	COG1881	PFAM PEBP family protein
TTX_RS03010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TTX_RS03020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TTX_RS03030	COG0174	glutamine synthetase
TTX_RS03045	COG1695	Transcriptional regulator
TTX_RS03065	COG2920	part of a sulfur-relay system
TTX_RS03070	COG2427	Protein of unknown function (DUF1641)
TTX_RS03080	COG0069	glutamate synthase activity
TTX_RS03090	COG2210	Belongs to the sulfur carrier protein TusA family
TTX_RS03100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TTX_RS03115	COG1489	DNA binding
TTX_RS03150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TTX_RS03165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TTX_RS03170	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TTX_RS03175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TTX_RS03180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TTX_RS03180	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TTX_RS03270	COG0717	Belongs to the dCTP deaminase family
TTX_RS03300	COG0574	Belongs to the PEP-utilizing enzyme family
TTX_RS03300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TTX_RS03335	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TTX_RS03340	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TTX_RS03345	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TTX_RS03415	COG2860	membrane
TTX_RS03430	COG1121	(ABC) transporter
TTX_RS03475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TTX_RS03520	COG2086	electron transfer activity
TTX_RS03525	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
TTX_RS03545	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TTX_RS03635	COG0419	ATPase involved in DNA repair
TTX_RS03650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TTX_RS03660	COG1136	(ABC) transporter
TTX_RS03670	COG2409	Drug exporters of the RND superfamily
TTX_RS03705	COG0330	HflC and HflK could
TTX_RS03730	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TTX_RS03735	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TTX_RS03740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TTX_RS03745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TTX_RS03750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TTX_RS03755	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TTX_RS03760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TTX_RS03765	COG0107	imidazoleglycerol-phosphate synthase activity
TTX_RS03770	COG0131	Imidazoleglycerol-phosphate dehydratase
TTX_RS03775	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TTX_RS03780	COG0519	Catalyzes the synthesis of GMP from XMP
TTX_RS03780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TTX_RS03785	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TTX_RS03790	COG2379	hydroxypyruvate reductase
TTX_RS03795	COG0129	dihydroxy-acid dehydratase activity
TTX_RS03805	COG1028	Short-chain dehydrogenase reductase Sdr
TTX_RS03810	COG0477	Major facilitator Superfamily
TTX_RS03815	COG0277	FAD linked oxidase domain protein
TTX_RS03825	COG0167	dihydroorotate dehydrogenase activity
TTX_RS03830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TTX_RS03830	COG0284	orotidine-5'-phosphate decarboxylase activity
TTX_RS03835	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
TTX_RS03845	COG0540	Belongs to the ATCase OTCase family
TTX_RS03880	COG0124	histidyl-tRNA synthetase
TTX_RS03930	COG1185	polyribonucleotide nucleotidyltransferase activity
TTX_RS03935	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TTX_RS03980	COG0556	nucleotide-excision repair
TTX_RS03995	COG0656	L-ascorbic acid biosynthetic process
TTX_RS04005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TTX_RS04025	COG1063	alcohol dehydrogenase
TTX_RS04035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TTX_RS04070	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TTX_RS04100	COG0436	Aminotransferase
TTX_RS04115	COG1201	RNA secondary structure unwinding
TTX_RS04135	COG3842	ATPase activity
TTX_RS04145	COG0351	phosphomethylpyrimidine kinase
TTX_RS04150	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TTX_RS04160	COG0494	nUDIX hydrolase
TTX_RS04245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TTX_RS04260	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TTX_RS04280	COG0183	Belongs to the thiolase family
TTX_RS04355	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
TTX_RS04390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TTX_RS04390	COG0574	Belongs to the PEP-utilizing enzyme family
TTX_RS04395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TTX_RS04430	COG1914	H( )-stimulated, divalent metal cation uptake system
TTX_RS04440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
TTX_RS04445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TTX_RS04450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TTX_RS04455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TTX_RS04465	COG0735	belongs to the Fur family
TTX_RS04475	COG0513	Belongs to the DEAD box helicase family
TTX_RS04490	COG0037	tRNA processing
TTX_RS04500	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TTX_RS04550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TTX_RS04570	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TTX_RS04585	COG0017	Asparaginyl-tRNA synthetase
TTX_RS04600	COG0494	nUDIX hydrolase
TTX_RS04605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TTX_RS04685	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TTX_RS04695	COG0308	aminopeptidase N
TTX_RS04700	COG1702	phosphate starvation-inducible protein PhoH
TTX_RS04705	COG1254	Belongs to the acylphosphatase family
TTX_RS04715	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TTX_RS04740	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TTX_RS04775	COG0175	sulfate reduction
TTX_RS04780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TTX_RS04800	COG1618	nucleotide phosphatase activity, acting on free nucleotides
TTX_RS04805	COG0017	Asparaginyl-tRNA synthetase
TTX_RS04820	COG0009	L-threonylcarbamoyladenylate synthase
TTX_RS04830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TTX_RS04855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TTX_RS04860	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TTX_RS04885	COG0494	nUDIX hydrolase
TTX_RS04920	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TTX_RS04930	COG0183	Belongs to the thiolase family
TTX_RS04935	COG1960	acyl-CoA dehydrogenase activity
TTX_RS04940	COG0318	PFAM AMP-dependent synthetase and ligase
TTX_RS04945	COG0318	PFAM AMP-dependent synthetase and ligase
TTX_RS04950	COG1363	Peptidase, m42
TTX_RS04955	COG1024	Enoyl-CoA hydratase
TTX_RS04960	COG0183	Belongs to the thiolase family
TTX_RS05020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TTX_RS05050	COG0163	prenyltransferase activity
TTX_RS05065	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TTX_RS05100	COG0495	leucyl-tRNA aminoacylation
TTX_RS05105	COG0805	protein transport
TTX_RS05120	COG1131	(ABC) transporter
TTX_RS05165	COG2255	four-way junction helicase activity
TTX_RS05170	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TTX_RS05185	COG1254	Belongs to the acylphosphatase family
TTX_RS05190	COG3842	ATPase activity
TTX_RS05205	COG0577	efflux transmembrane transporter activity
TTX_RS05210	COG0644	oxidoreductase
TTX_RS05225	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TTX_RS05230	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
TTX_RS05245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TTX_RS05250	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TTX_RS05265	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
TTX_RS05270	COG2264	protein methyltransferase activity
TTX_RS05285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TTX_RS05310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TTX_RS05315	COG1012	belongs to the aldehyde dehydrogenase family
TTX_RS05330	COG1053	succinate dehydrogenase
TTX_RS05340	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
TTX_RS05350	COG0517	IMP dehydrogenase activity
TTX_RS05350	COG0516	GMP reductase activity
TTX_RS05355	COG0517	IMP dehydrogenase activity
TTX_RS05355	COG0516	GMP reductase activity
TTX_RS05370	COG1960	acyl-CoA dehydrogenase activity
TTX_RS05375	COG1960	acyl-CoA dehydrogenase activity
TTX_RS05385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TTX_RS05400	COG1744	ABC transporter substrate-binding protein PnrA-like
TTX_RS05405	COG3845	ABC transporter
TTX_RS05410	COG4603	Belongs to the binding-protein-dependent transport system permease family
TTX_RS05415	COG1079	Belongs to the binding-protein-dependent transport system permease family
TTX_RS05420	COG0477	Major facilitator Superfamily
TTX_RS05425	COG0477	Major facilitator Superfamily
TTX_RS05430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TTX_RS05435	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TTX_RS05485	COG0517	IMP dehydrogenase activity
TTX_RS05485	COG0516	GMP reductase activity
TTX_RS05525	COG0303	'Molybdopterin
TTX_RS05560	COG1522	sequence-specific DNA binding
TTX_RS05570	COG4948	Mandelate Racemase Muconate Lactonizing
TTX_RS05575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TTX_RS05590	COG1968	undecaprenyl-diphosphatase activity
TTX_RS05615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TTX_RS05665	COG1328	CTP reductase activity
TTX_RS05695	COG2920	part of a sulfur-relay system
TTX_RS05705	COG2221	Nitrite and sulphite reductase 4Fe-4S
TTX_RS05750	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TTX_RS05755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TTX_RS05760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TTX_RS05775	COG0437	4 iron, 4 sulfur cluster binding
TTX_RS05780	COG0243	molybdopterin cofactor binding
TTX_RS05780	COG3383	formate dehydrogenase (NAD+) activity
TTX_RS05810	COG0419	ATPase involved in DNA repair
TTX_RS05840	COG0456	acetyltransferase
TTX_RS06035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TTX_RS06065	COG3383	formate dehydrogenase (NAD+) activity
TTX_RS06070	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TTX_RS06075	COG2855	membrane
TTX_RS06110	COG1830	Aldolase
TTX_RS06115	COG3276	selenocysteine insertion sequence binding
TTX_RS06125	COG1252	NADH dehydrogenase
TTX_RS06140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TTX_RS06150	COG0004	ammonium transporteR
TTX_RS06165	COG0004	ammonium transporteR
TTX_RS06190	COG2414	aldehyde ferredoxin oxidoreductase
TTX_RS06195	COG0114	fumarate hydratase activity
TTX_RS06220	COG1192	Involved in chromosome partitioning
TTX_RS06300	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
TTX_RS06305	COG0277	FAD linked oxidase domain protein
TTX_RS06320	COG1620	l-lactate permease
TTX_RS06325	COG1832	CoA-binding protein
TTX_RS06365	COG0494	nUDIX hydrolase
TTX_RS06380	COG1091	dTDP-4-dehydrorhamnose reductase activity
TTX_RS06405	COG1215	transferase activity, transferring glycosyl groups
TTX_RS06465	COG1215	transferase activity, transferring glycosyl groups
TTX_RS06505	COG0726	polysaccharide deacetylase
TTX_RS06510	COG0438	transferase activity, transferring glycosyl groups
TTX_RS06530	COG0438	transferase activity, transferring glycosyl groups
TTX_RS06535	COG0438	transferase activity, transferring glycosyl groups
TTX_RS06630	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TTX_RS06680	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TTX_RS06685	COG2414	aldehyde ferredoxin oxidoreductase
TTX_RS06705	COG0297	glycogen (starch) synthase activity
TTX_RS06720	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TTX_RS06725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TTX_RS06730	COG0135	phosphoribosylanthranilate isomerase activity
TTX_RS06740	COG1335	isochorismatase
TTX_RS06745	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TTX_RS06755	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TTX_RS06760	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TTX_RS06820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TTX_RS06830	COG0446	pyridine nucleotide-disulphide oxidoreductase
TTX_RS06835	COG0039	L-malate dehydrogenase activity
TTX_RS06850	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TTX_RS06865	COG1201	RNA secondary structure unwinding
TTX_RS06875	COG2301	Belongs to the HpcH HpaI aldolase family
TTX_RS06880	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TTX_RS06885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TTX_RS06890	COG0477	Major facilitator Superfamily
TTX_RS06910	COG0719	Fe-S assembly protein
TTX_RS06925	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TTX_RS06935	COG1199	ATP-dependent helicase activity
TTX_RS06940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TTX_RS06950	COG1444	tRNA N-acetyltransferase activity
TTX_RS06955	COG1013	pyruvate-flavodoxin oxidoreductase activity
TTX_RS06960	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TTX_RS06960	COG0674	pyruvate-flavodoxin oxidoreductase activity
TTX_RS06970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TTX_RS06970	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TTX_RS06980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TTX_RS06985	COG0546	phosphoglycolate phosphatase activity
TTX_RS07020	COG0302	gtp cyclohydrolase
TTX_RS07075	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
TTX_RS07135	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TTX_RS07155	COG0538	isocitrate dehydrogenase activity
TTX_RS07185	COG2079	MmgE PrpD family protein
TTX_RS07190	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
TTX_RS07265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TTX_RS07275	COG0372	Belongs to the citrate synthase family
TTX_RS07280	COG0281	malic enzyme
TTX_RS07290	COG0371	Dehydrogenase
TTX_RS07330	COG0072	phenylalanine-tRNA ligase activity
TTX_RS07340	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TTX_RS07365	COG1748	Saccharopine dehydrogenase
TTX_RS07370	COG0126	phosphoglycerate kinase activity
TTX_RS07385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TTX_RS07390	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TTX_RS07400	COG0501	Belongs to the peptidase M48B family
TTX_RS07410	COG1260	myo-inositol-1-phosphate synthase
TTX_RS07420	COG1215	transferase activity, transferring glycosyl groups
TTX_RS07440	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TTX_RS07455	COG0255	Belongs to the universal ribosomal protein uL29 family
TTX_RS07465	COG0113	porphobilinogen synthase activity
TTX_RS07480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TTX_RS07485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TTX_RS07490	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TTX_RS07495	COG0181	hydroxymethylbilane synthase activity
TTX_RS07510	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TTX_RS07655	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TTX_RS07665	COG0071	Belongs to the small heat shock protein (HSP20) family
TTX_RS07680	COG0423	glycine-tRNA ligase activity
TTX_RS07715	COG0531	amino acid
TTX_RS07750	COG0584	glycerophosphoryl diester phosphodiesterase
TTX_RS07760	COG0303	'Molybdopterin
TTX_RS07765	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TTX_RS07775	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TTX_RS07780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TTX_RS07785	COG1234	tRNA 3'-trailer cleavage
TTX_RS07815	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TTX_RS07845	COG0585	pseudouridine synthase activity
TTX_RS07855	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TTX_RS07860	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TTX_RS07895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TTX_RS07910	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TTX_RS07920	COG0528	UMP kinase activity
TTX_RS07930	COG0012	GTP binding
TTX_RS07940	COG0517	IMP dehydrogenase activity
TTX_RS07940	COG0617	tRNA 3'-terminal CCA addition
TTX_RS07940	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TTX_RS07950	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TTX_RS07960	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TTX_RS07965	COG0430	RNA-3'-phosphate cyclase activity
TTX_RS08030	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
TTX_RS08040	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TTX_RS08045	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TTX_RS08075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TTX_RS08080	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TTX_RS08085	COG0085	RNA polymerase activity
TTX_RS08095	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TTX_RS08160	COG1573	uracil-dna glycosylase
TTX_RS08250	COG0459	protein refolding
TTX_RS08270	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
TTX_RS08280	COG0483	inositol monophosphate 1-phosphatase activity
TTX_RS08310	COG2151	metal-sulfur cluster biosynthetic enzyme
TTX_RS08325	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
TTX_RS08340	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TTX_RS08355	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TTX_RS08360	COG1064	alcohol dehydrogenase
TTX_RS08415	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TTX_RS08435	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TTX_RS08440	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TTX_RS08445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TTX_RS08450	COG0710	3-dehydroquinate dehydratase activity
TTX_RS08455	COG0436	Aminotransferase
TTX_RS08460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TTX_RS08465	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TTX_RS08470	COG3958	Transketolase
TTX_RS08475	COG3959	Transketolase, thiamine diphosphate binding domain
TTX_RS08485	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TTX_RS08490	COG1013	pyruvate-flavodoxin oxidoreductase activity
TTX_RS08500	COG1584	GPR1 FUN34 yaaH family protein
TTX_RS08505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TTX_RS08510	COG1980	fructose-bisphosphate aldolase activity
TTX_RS08520	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
TTX_RS08550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TTX_RS08585	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TTX_RS08590	COG3833	ABC-type maltose transport systems, permease component
TTX_RS08595	COG1175	transmembrane transport
TTX_RS08600	COG2182	Extracellular solute-binding protein
TTX_RS08620	COG0674	pyruvate-flavodoxin oxidoreductase activity
TTX_RS08630	COG1012	belongs to the aldehyde dehydrogenase family
TTX_RS08675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TTX_RS08740	COG0552	protein localization to endoplasmic reticulum
TTX_RS08745	COG1730	sister chromatid segregation
TTX_RS08770	COG0504	CTP synthase activity
TTX_RS08780	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TTX_RS08795	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
TTX_RS08815	COG1252	NADH dehydrogenase
TTX_RS08845	COG2252	PERMEase
TTX_RS08855	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
TTX_RS08860	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TTX_RS08875	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TTX_RS08890	COG0134	indole-3-glycerol-phosphate synthase activity
TTX_RS08895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TTX_RS08895	COG0512	Glutamine amidotransferase of anthranilate synthase
TTX_RS08900	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TTX_RS08935	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TTX_RS08940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TTX_RS08945	COG0049	tRNA binding
TTX_RS09005	COG0673	inositol 2-dehydrogenase activity
TTX_RS09010	COG1546	Belongs to the CinA family
TTX_RS09010	COG1058	Belongs to the CinA family
TTX_RS09065	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TTX_RS09080	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TTX_RS09090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TTX_RS09100	COG1793	dna ligase
TTX_RS09130	COG0148	phosphopyruvate hydratase activity
TTX_RS09135	COG0215	cysteine-tRNA ligase activity
TTX_RS09155	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TTX_RS09165	COG1304	FMN binding
TTX_RS09170	COG1355	regulation of microtubule-based process
TTX_RS09175	COG0052	Belongs to the universal ribosomal protein uS2 family
TTX_RS09185	COG0489	protein tyrosine kinase activity
TTX_RS09195	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TTX_RS09200	COG1028	Short-chain dehydrogenase reductase Sdr
TTX_RS09210	COG0295	cytidine deaminase activity
TTX_RS09220	COG0315	cyclic pyranopterin monophosphate synthase activity
TTX_RS09230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TTX_RS09235	COG0515	serine threonine protein kinase
TTX_RS09235	COG2815	serine threonine protein kinase
TTX_RS09240	COG1716	ATPase activity
TTX_RS09255	COG0417	DNA replication proofreading
TTX_RS09265	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TTX_RS09270	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TTX_RS09275	COG1047	Peptidyl-prolyl cis-trans
TTX_RS09285	COG0459	protein refolding
TTX_RS09295	COG4133	protoheme IX ABC transporter activity
TTX_RS09315	COG0343	queuine tRNA-ribosyltransferase activity
TTX_RS09330	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TTX_RS09360	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TTX_RS09365	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TTX_RS09400	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TTX_RS09405	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TTX_RS09410	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TTX_RS09455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TTX_RS09465	COG0047	phosphoribosylformylglycinamidine synthase activity
TTX_RS09475	COG0151	Belongs to the GarS family
TTX_RS09485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TTX_RS09490	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TTX_RS09500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
TTX_RS09505	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TTX_RS09510	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TTX_RS09585	COG1110	DNA topoisomerase II activity
TTX_RS09595	COG2086	electron transfer activity
TTX_RS09600	COG0493	'glutamate synthase
TTX_RS09605	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TTX_RS09615	COG1121	(ABC) transporter
TTX_RS09620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TTX_RS09635	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TTX_RS09690	COG0501	Belongs to the peptidase M48B family
TTX_RS09700	COG0460	homoserine dehydrogenase
TTX_RS09705	COG0475	glutathione-regulated potassium exporter activity
TTX_RS09715	COG0527	aspartate kinase activity
TTX_RS09720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TTX_RS09725	COG0616	signal peptide processing
TTX_RS09730	COG2095	MarC family integral membrane protein
TTX_RS09740	COG1042	CoA-binding domain protein
TTX_RS09740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TTX_RS09740	COG0045	succinate-CoA ligase (ADP-forming) activity
TTX_RS09745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TTX_RS09745	COG1042	CoA-binding domain protein
TTX_RS09745	COG0045	succinate-CoA ligase (ADP-forming) activity
TTX_RS09785	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TTX_RS09785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TTX_RS09790	COG0612	Peptidase, M16
TTX_RS09835	COG1013	pyruvate-flavodoxin oxidoreductase activity
TTX_RS09840	COG0674	pyruvate-flavodoxin oxidoreductase activity
TTX_RS09845	COG1144	Oxidoreductase
TTX_RS09850	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TTX_RS09870	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TTX_RS09905	COG1418	mRNA catabolic process
TTX_RS09930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TTX_RS09960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TTX_RS09970	COG0456	acetyltransferase
TTX_RS09975	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TTX_RS10020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TTX_RS10035	COG1136	(ABC) transporter
TTX_RS10040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TTX_RS10100	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TTX_RS10125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TTX_RS10130	COG0516	GMP reductase activity
TTX_RS10140	COG0626	cystathionine gamma-synthase activity