locus-tag	class	description
TUZN_RS00020	COG0529	Catalyzes the synthesis of activated sulfate
TUZN_RS00060	COG0297	glycogen (starch) synthase activity
TUZN_RS00075	COG0438	transferase activity, transferring glycosyl groups
TUZN_RS00090	COG1216	Glycosyl transferase, family 2
TUZN_RS00115	COG0714	Associated with various cellular activities
TUZN_RS00155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TUZN_RS00160	COG0531	amino acid
TUZN_RS00190	COG1234	tRNA 3'-trailer cleavage
TUZN_RS00195	COG3842	ATPase activity
TUZN_RS00220	COG0437	4 iron, 4 sulfur cluster binding
TUZN_RS00225	COG0243	molybdopterin cofactor binding
TUZN_RS00230	COG3301	Polysulphide reductase, NrfD
TUZN_RS00290	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_RS00305	COG0495	leucyl-tRNA aminoacylation
TUZN_RS00310	COG0805	protein transport
TUZN_RS00340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TUZN_RS00355	COG0494	nUDIX hydrolase
TUZN_RS00360	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
TUZN_RS00380	COG0674	pyruvate-flavodoxin oxidoreductase activity
TUZN_RS00380	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TUZN_RS00385	COG1013	pyruvate-flavodoxin oxidoreductase activity
TUZN_RS00395	COG1444	tRNA N-acetyltransferase activity
TUZN_RS00420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TUZN_RS00445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TUZN_RS00450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TUZN_RS00605	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
TUZN_RS00620	COG1802	Transcriptional regulator
TUZN_RS00625	COG2721	sulfolactate sulfo-lyase activity
TUZN_RS00630	COG2721	sulfolactate sulfo-lyase activity
TUZN_RS00635	COG1012	belongs to the aldehyde dehydrogenase family
TUZN_RS00640	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_RS00655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TUZN_RS00660	COG0601	transmembrane transport
TUZN_RS00675	COG4608	Belongs to the ABC transporter superfamily
TUZN_RS00715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TUZN_RS00725	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TUZN_RS00760	COG1137	ATPase activity
TUZN_RS00780	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TUZN_RS00795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TUZN_RS00800	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TUZN_RS00815	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TUZN_RS00835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TUZN_RS00840	COG3830	Belongs to the UPF0237 family
TUZN_RS00845	COG2848	UPF0210 protein
TUZN_RS00870	COG1234	tRNA 3'-trailer cleavage
TUZN_RS00880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TUZN_RS00890	COG0395	ABC-type sugar transport system, permease component
TUZN_RS00940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TUZN_RS00955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TUZN_RS00960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TUZN_RS00985	COG1960	acyl-CoA dehydrogenase activity
TUZN_RS01030	COG0477	Major facilitator Superfamily
TUZN_RS01105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TUZN_RS01150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TUZN_RS01160	COG1607	acyl-coa hydrolase
TUZN_RS01175	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TUZN_RS01210	COG1132	(ABC) transporter
TUZN_RS01215	COG2814	Major facilitator Superfamily
TUZN_RS01230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TUZN_RS01245	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TUZN_RS01255	COG0174	glutamine synthetase
TUZN_RS01300	COG2427	Protein of unknown function (DUF1641)
TUZN_RS01315	COG0017	Asparaginyl-tRNA synthetase
TUZN_RS01320	COG2210	Belongs to the sulfur carrier protein TusA family
TUZN_RS01325	COG0425	Belongs to the sulfur carrier protein TusA family
TUZN_RS01345	COG1489	DNA binding
TUZN_RS01370	COG2226	methyltransferase
TUZN_RS01375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TUZN_RS01390	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TUZN_RS01395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TUZN_RS01400	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TUZN_RS01405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TUZN_RS01405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TUZN_RS01490	COG0717	Belongs to the dCTP deaminase family
TUZN_RS01505	COG2169	Transcriptional regulator
TUZN_RS01505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TUZN_RS01520	COG0574	Belongs to the PEP-utilizing enzyme family
TUZN_RS01520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TUZN_RS01550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TUZN_RS01600	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TUZN_RS01615	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TUZN_RS01640	COG1640	4-alpha-glucanotransferase
TUZN_RS01695	COG2860	membrane
TUZN_RS01800	COG2239	Acts as a magnesium transporter
TUZN_RS01860	COG1830	Aldolase
TUZN_RS01875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TUZN_RS01895	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TUZN_RS01915	COG0183	Belongs to the thiolase family
TUZN_RS01920	COG0107	imidazoleglycerol-phosphate synthase activity
TUZN_RS01925	COG0131	Imidazoleglycerol-phosphate dehydratase
TUZN_RS01935	COG0519	Catalyzes the synthesis of GMP from XMP
TUZN_RS01935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TUZN_RS01940	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TUZN_RS01965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TUZN_RS01975	COG0656	L-ascorbic acid biosynthetic process
TUZN_RS01990	COG0556	nucleotide-excision repair
TUZN_RS02040	COG1139	Iron-sulfur cluster binding protein
TUZN_RS02045	COG0277	FAD linked oxidase domain protein
TUZN_RS02050	COG0477	Major facilitator Superfamily
TUZN_RS02055	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_RS02065	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
TUZN_RS02070	COG0284	orotidine-5'-phosphate decarboxylase activity
TUZN_RS02075	COG0540	Belongs to the ATCase OTCase family
TUZN_RS02110	COG0549	Belongs to the carbamate kinase family
TUZN_RS02115	COG0124	histidyl-tRNA synthetase
TUZN_RS02130	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TUZN_RS02150	COG2078	PFAM AMMECR1 domain protein
TUZN_RS02155	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TUZN_RS02185	COG0330	HflC and HflK could
TUZN_RS02215	COG3634	alkyl hydroperoxide reductase activity
TUZN_RS02225	COG2409	Drug exporters of the RND superfamily
TUZN_RS02235	COG1136	(ABC) transporter
TUZN_RS02280	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TUZN_RS02385	COG0419	ATPase involved in DNA repair
TUZN_RS02400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TUZN_RS02405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TUZN_RS02435	COG1620	l-lactate permease
TUZN_RS02440	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
TUZN_RS02445	COG0277	FAD linked oxidase domain protein
TUZN_RS02480	COG1720	tRNA m6t6A37 methyltransferase activity
TUZN_RS02505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TUZN_RS02515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TUZN_RS02515	COG0574	Belongs to the PEP-utilizing enzyme family
TUZN_RS02555	COG1914	H( )-stimulated, divalent metal cation uptake system
TUZN_RS02560	COG0045	succinate-CoA ligase (ADP-forming) activity
TUZN_RS02565	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
TUZN_RS02570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TUZN_RS02575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TUZN_RS02590	COG0735	belongs to the Fur family
TUZN_RS02600	COG1201	RNA secondary structure unwinding
TUZN_RS02615	COG0037	tRNA processing
TUZN_RS02625	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TUZN_RS02665	COG0719	Fe-S assembly protein
TUZN_RS02675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TUZN_RS02685	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
TUZN_RS02705	COG0436	Aminotransferase
TUZN_RS02720	COG3842	ATPase activity
TUZN_RS02740	COG0667	Aldo Keto reductase
TUZN_RS02745	COG1201	RNA secondary structure unwinding
TUZN_RS02760	COG4962	Type ii secretion system protein e
TUZN_RS02770	COG2086	electron transfer activity
TUZN_RS02775	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TUZN_RS02780	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TUZN_RS02785	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TUZN_RS02790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TUZN_RS02795	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TUZN_RS02805	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TUZN_RS02810	COG0140	phosphoribosyl-ATP diphosphatase activity
TUZN_RS02815	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TUZN_RS02860	COG0644	oxidoreductase
TUZN_RS02870	COG1373	ATPase (AAA superfamily
TUZN_RS02880	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TUZN_RS02930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TUZN_RS02940	COG0351	phosphomethylpyrimidine kinase
TUZN_RS02955	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TUZN_RS02970	COG0017	Asparaginyl-tRNA synthetase
TUZN_RS02975	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TUZN_RS03085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TUZN_RS03095	COG0308	aminopeptidase N
TUZN_RS03100	COG1702	phosphate starvation-inducible protein PhoH
TUZN_RS03105	COG1254	Belongs to the acylphosphatase family
TUZN_RS03120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TUZN_RS03135	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TUZN_RS03160	COG0175	sulfate reduction
TUZN_RS03170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TUZN_RS03190	COG0017	Asparaginyl-tRNA synthetase
TUZN_RS03205	COG0009	L-threonylcarbamoyladenylate synthase
TUZN_RS03215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TUZN_RS03240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TUZN_RS03245	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TUZN_RS03300	COG0183	Belongs to the thiolase family
TUZN_RS03305	COG1024	Enoyl-CoA hydratase
TUZN_RS03315	COG0318	PFAM AMP-dependent synthetase and ligase
TUZN_RS03320	COG0667	Aldo Keto reductase
TUZN_RS03325	COG0318	PFAM AMP-dependent synthetase and ligase
TUZN_RS03330	COG1960	acyl-CoA dehydrogenase activity
TUZN_RS03335	COG0183	Belongs to the thiolase family
TUZN_RS03345	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TUZN_RS03360	COG2095	MarC family integral membrane protein
TUZN_RS03385	COG1271	oxidase subunit
TUZN_RS03410	COG2046	Belongs to the sulfate adenylyltransferase family
TUZN_RS03495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TUZN_RS03510	COG0813	purine-nucleoside phosphorylase activity
TUZN_RS03535	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TUZN_RS03540	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TUZN_RS03545	COG0372	Belongs to the citrate synthase family
TUZN_RS03555	COG0644	oxidoreductase
TUZN_RS03560	COG0577	efflux transmembrane transporter activity
TUZN_RS03575	COG1085	galactose-1-phosphate uridylyltransferase
TUZN_RS03580	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TUZN_RS03585	COG3842	ATPase activity
TUZN_RS03590	COG0793	Belongs to the peptidase S41A family
TUZN_RS03590	COG4946	Tricorn protease homolog
TUZN_RS03595	COG1254	Belongs to the acylphosphatase family
TUZN_RS03615	COG1063	alcohol dehydrogenase
TUZN_RS03660	COG2255	four-way junction helicase activity
TUZN_RS03665	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TUZN_RS03685	COG0419	ATPase involved in DNA repair
TUZN_RS03715	COG0656	L-ascorbic acid biosynthetic process
TUZN_RS03725	COG0393	Putative heavy-metal-binding
TUZN_RS03735	COG1832	CoA-binding protein
TUZN_RS03750	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TUZN_RS03755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TUZN_RS03765	COG0303	'Molybdopterin
TUZN_RS03770	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
TUZN_RS03805	COG0083	homoserine kinase activity
TUZN_RS03840	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TUZN_RS03850	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TUZN_RS03865	COG0165	Argininosuccinate lyase
TUZN_RS03870	COG0189	ligase activity
TUZN_RS03890	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TUZN_RS03905	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TUZN_RS03925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TUZN_RS03945	COG0657	acetylesterase activity
TUZN_RS03960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TUZN_RS03965	COG0432	Pfam Uncharacterised protein family UPF0047
TUZN_RS04030	COG1063	alcohol dehydrogenase
TUZN_RS04035	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
TUZN_RS04045	COG1024	Enoyl-CoA hydratase
TUZN_RS04050	COG0154	amidase activity
TUZN_RS04060	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TUZN_RS04065	COG3511	phospholipase C
TUZN_RS04085	COG0667	Aldo Keto reductase
TUZN_RS04100	COG1435	thymidine kinase activity
TUZN_RS04120	COG2084	Dehydrogenase
TUZN_RS04150	COG1131	(ABC) transporter
TUZN_RS04185	COG1592	Rubrerythrin
TUZN_RS04195	COG0434	BtpA family
TUZN_RS04215	COG1881	PFAM PEBP family protein
TUZN_RS04225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TUZN_RS04245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TUZN_RS04250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TUZN_RS04260	COG2814	Major facilitator Superfamily
TUZN_RS04280	COG0559	Belongs to the binding-protein-dependent transport system permease family
TUZN_RS04295	COG0517	IMP dehydrogenase activity
TUZN_RS04295	COG0516	GMP reductase activity
TUZN_RS04360	COG0004	ammonium transporteR
TUZN_RS04365	COG0347	Belongs to the P(II) protein family
TUZN_RS04370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TUZN_RS04380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TUZN_RS04400	COG1716	ATPase activity
TUZN_RS04465	COG1716	ATPase activity
TUZN_RS04480	COG0515	serine threonine protein kinase
TUZN_RS04500	COG1960	acyl-CoA dehydrogenase activity
TUZN_RS04505	COG1960	acyl-CoA dehydrogenase activity
TUZN_RS04525	COG0517	IMP dehydrogenase activity
TUZN_RS04525	COG0516	GMP reductase activity
TUZN_RS04545	COG1053	succinate dehydrogenase
TUZN_RS04560	COG1012	belongs to the aldehyde dehydrogenase family
TUZN_RS04570	COG1968	undecaprenyl-diphosphatase activity
TUZN_RS04580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TUZN_RS04585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TUZN_RS04590	COG4948	Mandelate Racemase Muconate Lactonizing
TUZN_RS04600	COG1522	sequence-specific DNA binding
TUZN_RS04630	COG4948	Mandelate Racemase Muconate Lactonizing
TUZN_RS04635	COG0569	domain protein
TUZN_RS04655	COG0303	'Molybdopterin
TUZN_RS04675	COG0438	transferase activity, transferring glycosyl groups
TUZN_RS04705	COG1175	transmembrane transport
TUZN_RS04710	COG0395	ABC-type sugar transport system, permease component
TUZN_RS04720	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
TUZN_RS04730	COG0649	NAD binding
TUZN_RS04745	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TUZN_RS04750	COG1013	pyruvate-flavodoxin oxidoreductase activity
TUZN_RS04755	COG0674	pyruvate-flavodoxin oxidoreductase activity
TUZN_RS04760	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TUZN_RS04765	COG1007	ATP synthesis coupled electron transport
TUZN_RS04795	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TUZN_RS04810	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TUZN_RS04820	COG0604	alcohol dehydrogenase
TUZN_RS04835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TUZN_RS04840	COG2217	Heavy metal translocating P-type atpase
TUZN_RS04860	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_RS04865	COG0114	fumarate hydratase activity
TUZN_RS04875	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
TUZN_RS04910	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
TUZN_RS04915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TUZN_RS04925	COG0022	dehydrogenase e1 component
TUZN_RS04940	COG0321	lipoyl(octanoyl) transferase activity
TUZN_RS04950	COG2897	thiosulfate sulfurtransferase activity
TUZN_RS04970	COG1741	Belongs to the pirin family
TUZN_RS04985	COG1331	Highly conserved protein containing a thioredoxin domain
TUZN_RS05005	COG0288	reversible hydration of carbon dioxide
TUZN_RS05050	COG2154	pterin-4-alpha-carbinolamine dehydratase
TUZN_RS05065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TUZN_RS05090	COG0425	Belongs to the sulfur carrier protein TusA family
TUZN_RS05130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TUZN_RS05135	COG1845	cytochrome c oxidase, subunit III
TUZN_RS05135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TUZN_RS05145	COG1999	signal sequence binding
TUZN_RS05150	COG0109	protoheme IX farnesyltransferase activity
TUZN_RS05240	COG0778	Nitroreductase
TUZN_RS05250	COG2391	methyltransferase activity
TUZN_RS05260	COG0425	Belongs to the sulfur carrier protein TusA family
TUZN_RS05305	COG0446	pyridine nucleotide-disulphide oxidoreductase
TUZN_RS05320	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
TUZN_RS05340	COG0149	triose-phosphate isomerase activity
TUZN_RS05385	COG0312	modulator of DNA gyrase
TUZN_RS05395	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TUZN_RS05405	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TUZN_RS05435	COG1012	belongs to the aldehyde dehydrogenase family
TUZN_RS05440	COG1254	Belongs to the acylphosphatase family
TUZN_RS05445	COG0425	Belongs to the sulfur carrier protein TusA family
TUZN_RS05510	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TUZN_RS05590	COG0235	Class ii aldolase
TUZN_RS05595	COG0445	tRNA wobble uridine modification
TUZN_RS05610	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TUZN_RS05665	COG0417	DNA replication proofreading
TUZN_RS05675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TUZN_RS05690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TUZN_RS05710	COG0444	Belongs to the ABC transporter superfamily
TUZN_RS05715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TUZN_RS05720	COG0601	transmembrane transport
TUZN_RS05740	COG3273	potassium ion transport
TUZN_RS05740	COG0471	metal ion transport
TUZN_RS05765	COG0667	Aldo Keto reductase
TUZN_RS05770	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TUZN_RS05810	COG0437	4 iron, 4 sulfur cluster binding
TUZN_RS05815	COG0243	molybdopterin cofactor binding
TUZN_RS05830	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TUZN_RS05835	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TUZN_RS05860	COG1881	PFAM PEBP family protein
TUZN_RS05865	COG1122	ATPase activity
TUZN_RS05875	COG0535	radical SAM domain protein
TUZN_RS05910	COG0243	molybdopterin cofactor binding
TUZN_RS05910	COG3383	formate dehydrogenase (NAD+) activity
TUZN_RS05915	COG0437	4 iron, 4 sulfur cluster binding
TUZN_RS05930	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TUZN_RS05975	COG0101	tRNA pseudouridine synthase activity
TUZN_RS05995	COG0537	adenosine 5'-monophosphoramidase activity
TUZN_RS06000	COG2030	dehydratase
TUZN_RS06015	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TUZN_RS06035	COG0109	protoheme IX farnesyltransferase activity
TUZN_RS06050	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_RS06065	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TUZN_RS06105	COG1966	Carbon starvation protein
TUZN_RS06115	COG0003	Pfam Anion-transporting ATPase
TUZN_RS06120	COG0003	Pfam Anion-transporting ATPase
TUZN_RS06145	COG0535	radical SAM domain protein
TUZN_RS06150	COG0477	Major facilitator Superfamily
TUZN_RS06155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TUZN_RS06180	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TUZN_RS06185	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TUZN_RS06200	COG0137	argininosuccinate synthase activity
TUZN_RS06215	COG0473	3-isopropylmalate dehydrogenase activity
TUZN_RS06225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TUZN_RS06230	COG0066	3-isopropylmalate dehydratase activity
TUZN_RS06235	COG0028	Belongs to the TPP enzyme family
TUZN_RS06245	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TUZN_RS06250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TUZN_RS06265	COG2723	6-phospho-beta-galactosidase activity
TUZN_RS06280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TUZN_RS06285	COG0444	Belongs to the ABC transporter superfamily
TUZN_RS06290	COG4608	Belongs to the ABC transporter superfamily
TUZN_RS06300	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_RS06305	COG0302	gtp cyclohydrolase
TUZN_RS06310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TUZN_RS06315	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TUZN_RS06325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TUZN_RS06335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TUZN_RS06345	COG4670	ketone body catabolic process
TUZN_RS06355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TUZN_RS06365	COG1271	oxidase subunit
TUZN_RS06380	COG0450	alkyl hydroperoxide reductase
TUZN_RS06420	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TUZN_RS06425	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TUZN_RS06460	COG0251	oxidation-reduction process
TUZN_RS06470	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TUZN_RS06475	COG0051	transcription antitermination factor activity, RNA binding
TUZN_RS06485	COG0641	radical SAM
TUZN_RS06505	COG0154	amidase activity
TUZN_RS06530	COG0589	response to stress
TUZN_RS06570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TUZN_RS06575	COG0006	proline dipeptidase activity
TUZN_RS06595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TUZN_RS06615	COG0626	cystathionine gamma-synthase activity
TUZN_RS06625	COG0517	IMP dehydrogenase activity
TUZN_RS06625	COG0516	GMP reductase activity
TUZN_RS06630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TUZN_RS06635	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TUZN_RS06655	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TUZN_RS06725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TUZN_RS06735	COG1136	(ABC) transporter
TUZN_RS06745	COG0577	efflux transmembrane transporter activity
TUZN_RS06755	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TUZN_RS06830	COG1324	tolerance protein
TUZN_RS06835	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TUZN_RS06840	COG0456	acetyltransferase
TUZN_RS06860	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TUZN_RS06890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TUZN_RS06955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TUZN_RS06965	COG0517	IMP dehydrogenase activity
TUZN_RS06980	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TUZN_RS06985	COG1144	Oxidoreductase
TUZN_RS06990	COG0674	pyruvate-flavodoxin oxidoreductase activity
TUZN_RS06995	COG1013	pyruvate-flavodoxin oxidoreductase activity
TUZN_RS07035	COG0477	Major facilitator Superfamily
TUZN_RS07045	COG0616	signal peptide processing
TUZN_RS07050	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TUZN_RS07055	COG0527	aspartate kinase activity
TUZN_RS07065	COG0475	glutathione-regulated potassium exporter activity
TUZN_RS07070	COG0460	homoserine dehydrogenase
TUZN_RS07095	COG0501	Belongs to the peptidase M48B family
TUZN_RS07100	COG0494	nUDIX hydrolase
TUZN_RS07130	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TUZN_RS07130	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TUZN_RS07135	COG0612	Peptidase, M16
TUZN_RS07175	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TUZN_RS07180	COG0493	'glutamate synthase
TUZN_RS07185	COG2086	electron transfer activity
TUZN_RS07195	COG1110	DNA topoisomerase II activity
TUZN_RS07245	COG0018	arginyl-trna synthetase
TUZN_RS07265	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TUZN_RS07285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TUZN_RS07290	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TUZN_RS07325	COG1131	(ABC) transporter
TUZN_RS07345	COG3511	phospholipase C
TUZN_RS07380	COG3256	nitric oxide reductase
TUZN_RS07390	COG0668	transmembrane transport
TUZN_RS07430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TUZN_RS07435	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TUZN_RS07440	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TUZN_RS07490	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TUZN_RS07495	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TUZN_RS07510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TUZN_RS07545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TUZN_RS07560	COG0343	queuine tRNA-ribosyltransferase activity
TUZN_RS07590	COG0459	protein refolding
TUZN_RS07600	COG1047	Peptidyl-prolyl cis-trans
TUZN_RS07605	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
TUZN_RS07610	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TUZN_RS07620	COG0417	DNA replication proofreading
TUZN_RS07635	COG1716	ATPase activity
TUZN_RS07645	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TUZN_RS07655	COG0315	cyclic pyranopterin monophosphate synthase activity
TUZN_RS07660	COG0295	cytidine deaminase activity
TUZN_RS07670	COG1028	Short-chain dehydrogenase reductase Sdr
TUZN_RS07680	COG0489	protein tyrosine kinase activity
TUZN_RS07690	COG0052	Belongs to the universal ribosomal protein uS2 family
TUZN_RS07695	COG1355	regulation of microtubule-based process
TUZN_RS07700	COG1304	FMN binding
TUZN_RS07740	COG0215	cysteine-tRNA ligase activity
TUZN_RS07745	COG0148	phosphopyruvate hydratase activity
TUZN_RS07775	COG1793	dna ligase
TUZN_RS07795	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TUZN_RS07810	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TUZN_RS07820	COG0142	geranyltranstransferase activity
TUZN_RS07850	COG0673	inositol 2-dehydrogenase activity
TUZN_RS07875	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TUZN_RS07905	COG0049	tRNA binding
TUZN_RS07910	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TUZN_RS07915	COG1067	ATP-dependent peptidase activity
TUZN_RS07915	COG0470	DNA polymerase III
TUZN_RS07950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TUZN_RS07955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TUZN_RS07955	COG0512	Glutamine amidotransferase of anthranilate synthase
TUZN_RS07960	COG0134	indole-3-glycerol-phosphate synthase activity
TUZN_RS07975	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TUZN_RS07980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TUZN_RS07985	COG0446	pyridine nucleotide-disulphide oxidoreductase
TUZN_RS07995	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TUZN_RS08000	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
TUZN_RS08005	COG0746	molybdenum cofactor guanylyltransferase activity
TUZN_RS08010	COG2252	PERMEase
TUZN_RS08025	COG1546	Belongs to the CinA family
TUZN_RS08025	COG1058	Belongs to the CinA family
TUZN_RS08055	COG1252	NADH dehydrogenase
TUZN_RS08075	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
TUZN_RS08090	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TUZN_RS08100	COG0504	CTP synthase activity
TUZN_RS08125	COG1730	sister chromatid segregation
TUZN_RS08130	COG0552	protein localization to endoplasmic reticulum
TUZN_RS08150	COG0081	regulation of translation
TUZN_RS08170	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
TUZN_RS08195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TUZN_RS08200	COG1079	Belongs to the binding-protein-dependent transport system permease family
TUZN_RS08210	COG3845	ABC transporter
TUZN_RS08215	COG1744	ABC transporter substrate-binding protein PnrA-like
TUZN_RS08240	COG0326	Molecular chaperone. Has ATPase activity
TUZN_RS08260	COG2890	protein-(glutamine-N5) methyltransferase activity
TUZN_RS08275	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TUZN_RS08320	COG1013	pyruvate-flavodoxin oxidoreductase activity
TUZN_RS08325	COG0674	pyruvate-flavodoxin oxidoreductase activity
TUZN_RS08350	COG1175	transmembrane transport
TUZN_RS08355	COG3833	ABC-type maltose transport systems, permease component
TUZN_RS08360	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TUZN_RS08385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TUZN_RS08415	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
TUZN_RS08425	COG1980	fructose-bisphosphate aldolase activity
TUZN_RS08430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TUZN_RS08435	COG1584	GPR1 FUN34 yaaH family protein
TUZN_RS08445	COG2095	MarC family integral membrane protein
TUZN_RS08460	COG1013	pyruvate-flavodoxin oxidoreductase activity
TUZN_RS08465	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TUZN_RS08475	COG3959	Transketolase, thiamine diphosphate binding domain
TUZN_RS08480	COG3958	Transketolase
TUZN_RS08485	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TUZN_RS08490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TUZN_RS08495	COG0436	Aminotransferase
TUZN_RS08500	COG4946	Tricorn protease homolog
TUZN_RS08500	COG1506	peptidase
TUZN_RS08500	COG0823	Involved in the tonB-independent uptake of proteins
TUZN_RS08505	COG0710	3-dehydroquinate dehydratase activity
TUZN_RS08510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TUZN_RS08515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TUZN_RS08520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TUZN_RS08625	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TUZN_RS08660	COG0459	protein refolding
TUZN_RS08680	COG2151	metal-sulfur cluster biosynthetic enzyme
TUZN_RS08685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TUZN_RS08700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TUZN_RS08705	COG1064	alcohol dehydrogenase
TUZN_RS08725	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
TUZN_RS08735	COG0483	inositol monophosphate 1-phosphatase activity
TUZN_RS08750	COG1078	dGTPase activity
TUZN_RS08820	COG1573	uracil-dna glycosylase
TUZN_RS08885	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TUZN_RS08895	COG0085	RNA polymerase activity
TUZN_RS08900	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TUZN_RS08905	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TUZN_RS08935	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TUZN_RS08940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TUZN_RS08955	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
TUZN_RS09020	COG0430	RNA-3'-phosphate cyclase activity
TUZN_RS09025	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TUZN_RS09055	COG0012	GTP binding
TUZN_RS09065	COG0528	UMP kinase activity
TUZN_RS09105	COG2271	Major facilitator Superfamily
TUZN_RS09190	COG0189	ligase activity
TUZN_RS09195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TUZN_RS09255	COG0303	'Molybdopterin
TUZN_RS09260	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TUZN_RS09270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TUZN_RS09275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TUZN_RS09280	COG1234	tRNA 3'-trailer cleavage
TUZN_RS09365	COG0585	pseudouridine synthase activity
TUZN_RS09375	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TUZN_RS09380	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TUZN_RS09430	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TUZN_RS09445	COG0010	Belongs to the arginase family
TUZN_RS09450	COG0423	glycine-tRNA ligase activity
TUZN_RS09465	COG0071	Belongs to the small heat shock protein (HSP20) family
TUZN_RS09475	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TUZN_RS09515	COG0454	-acetyltransferase
TUZN_RS09515	COG0456	acetyltransferase
TUZN_RS09595	COG1446	asparaginase
TUZN_RS09600	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TUZN_RS09605	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TUZN_RS09615	COG0181	hydroxymethylbilane synthase activity
TUZN_RS09620	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TUZN_RS09625	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TUZN_RS09630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TUZN_RS09640	COG1648	precorrin-2 dehydrogenase activity
TUZN_RS09640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TUZN_RS09645	COG0113	porphobilinogen synthase activity
TUZN_RS09650	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TUZN_RS09675	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TUZN_RS09680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TUZN_RS09690	COG0247	lactate metabolic process
TUZN_RS09690	COG2181	nitrate reductase activity
TUZN_RS09695	COG1215	transferase activity, transferring glycosyl groups
TUZN_RS09700	COG1260	myo-inositol-1-phosphate synthase
TUZN_RS09710	COG0501	Belongs to the peptidase M48B family
TUZN_RS09715	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TUZN_RS09720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TUZN_RS09735	COG0126	phosphoglycerate kinase activity
TUZN_RS09740	COG1748	Saccharopine dehydrogenase
TUZN_RS09745	COG0589	response to stress
TUZN_RS09760	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TUZN_RS09765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TUZN_RS09775	COG0072	phenylalanine-tRNA ligase activity
TUZN_RS09815	COG0371	Dehydrogenase
TUZN_RS09830	COG0281	malic enzyme
TUZN_RS09840	COG0372	Belongs to the citrate synthase family
TUZN_RS09850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TUZN_RS09915	COG1522	sequence-specific DNA binding
TUZN_RS09920	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
TUZN_RS09925	COG2079	MmgE PrpD family protein
TUZN_RS09930	COG0538	isocitrate dehydrogenase activity
TUZN_RS09955	COG0492	ferredoxin-NADP+ reductase activity
TUZN_RS09960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TUZN_RS10030	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
TUZN_RS10040	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TUZN_RS10090	COG0477	Major facilitator Superfamily
TUZN_RS10130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TUZN_RS10135	COG1024	Enoyl-CoA hydratase
TUZN_RS10140	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TUZN_RS10160	COG0730	response to heat
TUZN_RS10190	COG0297	glycogen (starch) synthase activity
TUZN_RS10200	COG0159	tryptophan synthase activity
TUZN_RS10210	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TUZN_RS10215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TUZN_RS10230	COG1335	isochorismatase
TUZN_RS10235	COG4555	ABC transporter
TUZN_RS10260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TUZN_RS10275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TUZN_RS10290	COG0200	Binds to the 23S rRNA
TUZN_RS10315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TUZN_RS10320	COG1201	RNA secondary structure unwinding
TUZN_RS10335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TUZN_RS10340	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TUZN_RS10355	COG0039	L-malate dehydrogenase activity
TUZN_RS10400	COG0714	Associated with various cellular activities
TUZN_RS10420	COG2301	Belongs to the HpcH HpaI aldolase family
TUZN_RS10430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TUZN_RS10435	COG0477	Major facilitator Superfamily
TUZN_RS10495	COG2414	aldehyde ferredoxin oxidoreductase
TUZN_RS10525	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TUZN_RS10530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TUZN_RS10535	COG0477	Major facilitator Superfamily
TUZN_RS10540	COG0477	Major facilitator Superfamily
TUZN_RS10565	COG1007	ATP synthesis coupled electron transport
TUZN_RS10575	COG0651	ATP synthesis coupled electron transport
TUZN_RS10600	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TUZN_RS10630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TUZN_RS10630	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TUZN_RS10645	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
TUZN_RS10650	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
TUZN_RS10655	COG0409	Hydrogenase expression formation protein
TUZN_RS10690	COG0310	cobalt ion transport
TUZN_RS10705	COG1122	ATPase activity
TUZN_RS10760	COG0864	Transcriptional regulator
TUZN_RS10765	COG0375	protein maturation
TUZN_RS10770	COG0489	protein tyrosine kinase activity
TUZN_RS10775	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TUZN_RS10785	COG0309	Hydrogenase expression formation protein (HypE)
TUZN_RS10790	COG2220	Zn-dependent hydrolases of the beta-lactamase fold