locus-tag	class	description
BG95_RS00020	COG0514	ATP-dependent DNA helicase (RecQ)
BG95_RS00025	COG0758	DNA mediated transformation
BG95_RS00030	COG1752	Esterase of the alpha-beta hydrolase superfamily
BG95_RS00060	COG0768	penicillin binding
BG95_RS00070	COG0275	rRNA processing
BG95_RS00090	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BG95_RS00095	COG4608	Belongs to the ABC transporter superfamily
BG95_RS00105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG95_RS00110	COG0601	transmembrane transport
BG95_RS00115	COG0322	excinuclease ABC activity
BG95_RS00125	COG0509	glycine decarboxylation via glycine cleavage system
BG95_RS00130	COG1918	ferrous iron import across plasma membrane
BG95_RS00130	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BG95_RS00135	COG1918	ferrous iron import across plasma membrane
BG95_RS00150	COG1555	photosystem II stabilization
BG95_RS00150	COG1596	polysaccharide export
BG95_RS00155	COG1355	regulation of microtubule-based process
BG95_RS00160	COG4796	Type ii and iii secretion system protein
BG95_RS00190	COG1459	type II secretion system
BG95_RS00195	COG1122	ATPase activity
BG95_RS00200	COG2813	Specifically methylates the guanine in position
BG95_RS00205	COG1773	rubredoxin
BG95_RS00205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BG95_RS00210	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BG95_RS00220	COG0268	Binds directly to 16S ribosomal RNA
BG95_RS00225	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BG95_RS00240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BG95_RS00245	COG1923	regulation of RNA biosynthetic process
BG95_RS00260	COG0572	uridine kinase
BG95_RS00265	COG1530	ribonuclease E activity
BG95_RS00270	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BG95_RS00275	COG2131	deaminase
BG95_RS00280	COG1013	pyruvate-flavodoxin oxidoreductase activity
BG95_RS00295	COG2201	protein-glutamate methylesterase activity
BG95_RS00305	COG0840	transmembrane signaling receptor activity
BG95_RS00310	COG2986	histidine ammonia-lyase
BG95_RS00350	COG1363	Peptidase, m42
BG95_RS00375	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BG95_RS00380	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BG95_RS00390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BG95_RS00390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BG95_RS00410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BG95_RS00415	COG0058	SHG alpha-glucan phosphorylase activity
BG95_RS00420	COG0681	Belongs to the peptidase S26 family
BG95_RS00425	COG0335	large ribosomal subunit rRNA binding
BG95_RS00430	COG4752	Belongs to the RNA methyltransferase TrmD family
BG95_RS00435	COG0336	Belongs to the RNA methyltransferase TrmD family
BG95_RS00440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BG95_RS00445	COG1837	Belongs to the UPF0109 family
BG95_RS00450	COG0228	four-way junction DNA binding
BG95_RS00455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BG95_RS00480	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
BG95_RS00495	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BG95_RS00505	COG0840	transmembrane signaling receptor activity
BG95_RS00510	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BG95_RS00510	COG0731	radical SAM domain protein
BG95_RS00525	COG3279	Response regulator of the LytR AlgR family
BG95_RS00530	COG1966	Carbon starvation protein
BG95_RS00535	COG1215	transferase activity, transferring glycosyl groups
BG95_RS00550	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BG95_RS00580	COG1337	RAMP superfamily
BG95_RS00590	COG1353	crispr-associated protein
BG95_RS00620	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BG95_RS00625	COG1518	maintenance of DNA repeat elements
BG95_RS00630	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BG95_RS00640	COG0154	amidase activity
BG95_RS00655	COG1653	transport
BG95_RS00660	COG0438	transferase activity, transferring glycosyl groups
BG95_RS00670	COG5002	protein histidine kinase activity
BG95_RS00675	COG0745	RESPONSE REGULATOR receiver
BG95_RS00680	COG0704	Plays a role in the regulation of phosphate uptake
BG95_RS00685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BG95_RS00705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG95_RS00720	COG1105	Belongs to the carbohydrate kinase PfkB family
BG95_RS00725	COG1028	Short-chain dehydrogenase reductase Sdr
BG95_RS00730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BG95_RS00735	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BG95_RS00740	COG0745	RESPONSE REGULATOR receiver
BG95_RS00745	COG5002	protein histidine kinase activity
BG95_RS00760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BG95_RS00765	COG0166	Belongs to the GPI family
BG95_RS00775	COG0237	dephospho-CoA kinase activity
BG95_RS00785	COG0556	nucleotide-excision repair
BG95_RS00790	COG1293	RNA-binding protein homologous to eukaryotic snRNP
BG95_RS00815	COG1323	Belongs to the UPF0348 family
BG95_RS00820	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BG95_RS00825	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BG95_RS00830	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BG95_RS00840	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BG95_RS00840	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BG95_RS00845	COG0235	Class ii aldolase
BG95_RS00855	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BG95_RS00855	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BG95_RS00865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BG95_RS00875	COG0840	transmembrane signaling receptor activity
BG95_RS00890	COG1785	Belongs to the alkaline phosphatase family
BG95_RS00905	COG0045	succinate-CoA ligase (ADP-forming) activity
BG95_RS00915	COG0569	domain protein
BG95_RS00915	COG2985	domain, Protein
BG95_RS00925	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BG95_RS00935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BG95_RS00940	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BG95_RS00945	COG2171	N-acyltransferase activity
BG95_RS00950	COG0527	aspartate kinase activity
BG95_RS00955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BG95_RS00965	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BG95_RS00975	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BG95_RS00980	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BG95_RS00985	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BG95_RS00990	COG1454	alcohol dehydrogenase
BG95_RS00995	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BG95_RS01010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG95_RS01015	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BG95_RS01020	COG0674	pyruvate-flavodoxin oxidoreductase activity
BG95_RS01020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BG95_RS01030	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BG95_RS01040	COG1122	ATPase activity
BG95_RS01045	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
BG95_RS01050	COG0205	6-phosphofructokinase activity
BG95_RS01060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG95_RS01065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BG95_RS01070	COG1862	Preprotein translocase
BG95_RS01075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BG95_RS01085	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BG95_RS01090	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BG95_RS01105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BG95_RS01125	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BG95_RS01125	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BG95_RS01140	COG1193	negative regulation of DNA recombination
BG95_RS01150	COG0306	phosphate transporter
BG95_RS01165	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BG95_RS01175	COG0549	Belongs to the carbamate kinase family
BG95_RS01180	COG0280	phosphate acetyltransferase
BG95_RS01190	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BG95_RS01195	COG1141	Ferredoxin
BG95_RS01205	COG1744	ABC transporter substrate-binding protein PnrA-like
BG95_RS01210	COG3845	ABC transporter
BG95_RS01215	COG4603	Belongs to the binding-protein-dependent transport system permease family
BG95_RS01220	COG1079	Belongs to the binding-protein-dependent transport system permease family
BG95_RS01235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BG95_RS01240	COG1307	EDD domain protein, DegV family
BG95_RS01245	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BG95_RS01250	COG0542	response to heat
BG95_RS01280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BG95_RS01290	COG1335	isochorismatase
BG95_RS01295	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BG95_RS01300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BG95_RS01305	COG1136	(ABC) transporter
BG95_RS01315	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BG95_RS01320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BG95_RS01325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BG95_RS01335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BG95_RS01350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BG95_RS01355	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BG95_RS01360	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BG95_RS01360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BG95_RS01365	COG0307	riboflavin synthase, alpha
BG95_RS01370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BG95_RS01370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BG95_RS01375	COG0840	transmembrane signaling receptor activity
BG95_RS01380	COG0822	iron-sulfur transferase activity
BG95_RS01385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BG95_RS01390	COG0719	Fe-S assembly protein
BG95_RS01395	COG0719	Fe-S assembly protein
BG95_RS01410	COG0459	protein refolding
BG95_RS01415	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BG95_RS01430	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BG95_RS01440	COG0312	modulator of DNA gyrase
BG95_RS01445	COG0312	modulator of DNA gyrase
BG95_RS01460	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BG95_RS01465	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BG95_RS01475	COG2378	regulation of single-species biofilm formation
BG95_RS01500	COG1518	maintenance of DNA repeat elements
BG95_RS01500	COG1468	defense response to virus
BG95_RS01510	COG0442	prolyl-tRNA aminoacylation
BG95_RS01515	COG0215	cysteine-tRNA ligase activity
BG95_RS01520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BG95_RS01525	COG2233	PERMEase
BG95_RS01535	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BG95_RS01540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BG95_RS01545	COG1335	isochorismatase
BG95_RS01550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BG95_RS01565	COG0297	glycogen (starch) synthase activity
BG95_RS01575	COG3290	protein histidine kinase activity
BG95_RS01575	COG3829	transcription factor binding
BG95_RS01585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BG95_RS01590	COG2379	hydroxypyruvate reductase
BG95_RS01595	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BG95_RS01600	COG0484	heat shock protein binding
BG95_RS01605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BG95_RS01610	COG1420	regulation of RNA biosynthetic process
BG95_RS01615	COG0477	Major facilitator Superfamily
BG95_RS01620	COG1827	regulation of RNA biosynthetic process
BG95_RS01625	COG1272	protein, Hemolysin III
BG95_RS01630	COG1047	Peptidyl-prolyl cis-trans
BG95_RS01645	COG1363	Peptidase, m42
BG95_RS01655	COG1758	RNA polymerase activity
BG95_RS01660	COG0194	GDP metabolic process
BG95_RS01665	COG2052	Domain of unknown function (DUF370)
BG95_RS01700	COG3426	butyrate kinase activity
BG95_RS01705	COG0280	phosphate acetyltransferase
BG95_RS01710	COG3426	butyrate kinase activity
BG95_RS01715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BG95_RS01720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BG95_RS01725	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BG95_RS01740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG95_RS01745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BG95_RS01790	COG2359	stage V sporulation protein S
BG95_RS01800	COG0737	Belongs to the 5'-nucleotidase family
BG95_RS01805	COG1132	(ABC) transporter
BG95_RS01835	COG0301	tRNA thio-modification
BG95_RS01840	COG1937	Protein conserved in bacteria
BG95_RS01845	COG1132	(ABC) transporter
BG95_RS01865	COG0446	pyridine nucleotide-disulphide oxidoreductase
BG95_RS01880	COG0534	Mate efflux family protein
BG95_RS01885	COG0667	Aldo Keto reductase
BG95_RS01900	COG1131	(ABC) transporter
BG95_RS01910	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BG95_RS01910	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BG95_RS01915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BG95_RS01915	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BG95_RS01930	COG1573	uracil-dna glycosylase
BG95_RS01935	COG0574	Belongs to the PEP-utilizing enzyme family
BG95_RS01935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BG95_RS01945	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BG95_RS01950	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BG95_RS01955	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BG95_RS01960	COG0193	aminoacyl-tRNA hydrolase activity
BG95_RS01980	COG0529	Catalyzes the synthesis of activated sulfate
BG95_RS01985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BG95_RS01990	COG4974	Belongs to the 'phage' integrase family
BG95_RS01995	COG0148	phosphopyruvate hydratase activity
BG95_RS02010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BG95_RS02025	COG0116	Belongs to the methyltransferase superfamily
BG95_RS02030	COG1993	acr, cog1993
BG95_RS02035	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BG95_RS02045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BG95_RS02050	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BG95_RS02060	COG2264	protein methyltransferase activity
BG95_RS02065	COG0739	heme binding
BG95_RS02070	COG1607	acyl-coa hydrolase
BG95_RS02075	COG3246	L-lysine catabolic process to acetate
BG95_RS02080	COG0604	alcohol dehydrogenase
BG95_RS02085	COG1509	lysine 2,3-aminomutase activity
BG95_RS02090	COG2030	dehydratase
BG95_RS02100	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BG95_RS02105	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BG95_RS02110	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BG95_RS02140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BG95_RS02145	COG0037	tRNA processing
BG95_RS02160	COG1968	undecaprenyl-diphosphatase activity
BG95_RS02165	COG1228	amidohydrolase
BG95_RS02180	COG0424	maF-like protein
BG95_RS02185	COG2003	Belongs to the UPF0758 family
BG95_RS02200	COG1215	transferase activity, transferring glycosyl groups
BG95_RS02205	COG0463	Glycosyl transferase, family 2
BG95_RS02230	COG0793	Belongs to the peptidase S41A family
BG95_RS02250	COG1713	HD superfamily hydrolase involved in NAD metabolism
BG95_RS02255	COG1550	Protein conserved in bacteria
BG95_RS02260	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BG95_RS02265	COG0009	L-threonylcarbamoyladenylate synthase
BG95_RS02275	COG0481	GTPase activity
BG95_RS02280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BG95_RS02285	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BG95_RS02290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BG95_RS02295	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BG95_RS02305	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BG95_RS02315	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BG95_RS02320	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BG95_RS02330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BG95_RS02335	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BG95_RS02340	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BG95_RS02345	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BG95_RS02360	COG1461	Dihydroxyacetone kinase
BG95_RS02370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BG95_RS02375	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BG95_RS02380	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BG95_RS02390	COG0495	leucyl-tRNA aminoacylation
BG95_RS02395	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BG95_RS02405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BG95_RS02410	COG0750	zinc metalloprotease
BG95_RS02415	COG2203	Gaf domain
BG95_RS02415	COG2199	diguanylate cyclase activity
BG95_RS02420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BG95_RS02425	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BG95_RS02435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BG95_RS02440	COG0543	2 iron, 2 sulfur cluster binding
BG95_RS02445	COG0167	dihydroorotate dehydrogenase activity
BG95_RS02450	COG0284	orotidine-5'-phosphate decarboxylase activity
BG95_RS02455	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BG95_RS02480	COG2183	response to ionizing radiation
BG95_RS02485	COG0835	chemotaxis
BG95_RS02490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BG95_RS02500	COG1278	Cold shock
BG95_RS02505	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BG95_RS02510	COG0095	Lipoate-protein ligase
BG95_RS02530	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BG95_RS02535	COG3852	Histidine kinase
BG95_RS02540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BG95_RS02550	COG1307	EDD domain protein, DegV family
BG95_RS02560	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BG95_RS02565	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BG95_RS02570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BG95_RS02575	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BG95_RS02580	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BG95_RS02585	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BG95_RS02605	COG0006	proline dipeptidase activity
BG95_RS02615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BG95_RS02620	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BG95_RS02620	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BG95_RS02630	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BG95_RS02635	COG5002	protein histidine kinase activity
BG95_RS02640	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BG95_RS02645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BG95_RS02650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BG95_RS02660	COG0537	adenosine 5'-monophosphoramidase activity
BG95_RS02665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BG95_RS02675	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BG95_RS02685	COG4112	unkown
BG95_RS02690	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BG95_RS02695	COG1067	ATP-dependent peptidase activity
BG95_RS02700	COG0180	Tryptophanyl-tRNA synthetase
BG95_RS02705	COG0668	transmembrane transport
BG95_RS02710	COG0840	transmembrane signaling receptor activity
BG95_RS02725	COG4786	Flagellar basal body rod
BG95_RS02725	COG1256	bacterial-type flagellum assembly
BG95_RS02725	COG1256	bacterial-type flagellum assembly
BG95_RS02725	COG4786	Flagellar basal body rod
BG95_RS02730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG95_RS02775	COG1760	l-serine dehydratase
BG95_RS02785	COG1543	Belongs to the glycosyl hydrolase 57 family
BG95_RS02790	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BG95_RS02795	COG1144	Oxidoreductase
BG95_RS02800	COG0674	pyruvate-flavodoxin oxidoreductase activity
BG95_RS02805	COG1013	pyruvate-flavodoxin oxidoreductase activity
BG95_RS02815	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BG95_RS02850	COG2203	Gaf domain
BG95_RS02850	COG2199	diguanylate cyclase activity
BG95_RS02855	COG0542	response to heat
BG95_RS02860	COG1773	rubredoxin
BG95_RS02880	COG4399	Belongs to the UPF0754 family
BG95_RS02885	COG1187	pseudouridine synthase activity
BG95_RS02895	COG1074	ATP-dependent DNA helicase activity
BG95_RS02910	COG0776	regulation of translation
BG95_RS02915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BG95_RS02920	COG0432	Pfam Uncharacterised protein family UPF0047
BG95_RS02930	COG0803	Belongs to the bacterial solute-binding protein 9 family
BG95_RS02935	COG1121	(ABC) transporter
BG95_RS02940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BG95_RS02950	COG0196	riboflavin kinase activity
BG95_RS02955	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BG95_RS02970	COG2252	PERMEase
BG95_RS03025	COG1131	(ABC) transporter
BG95_RS03030	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BG95_RS03050	COG1523	belongs to the glycosyl hydrolase 13 family
BG95_RS03055	COG0745	RESPONSE REGULATOR receiver
BG95_RS03060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BG95_RS03070	COG0697	spore germination
BG95_RS03075	COG1077	Cell shape determining protein MreB Mrl
BG95_RS03080	COG4786	Flagellar basal body rod
BG95_RS03095	COG0765	amino acid transport
BG95_RS03100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BG95_RS03105	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BG95_RS03110	COG0416	fatty acid biosynthetic process
BG95_RS03115	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BG95_RS03130	COG1766	The M ring may be actively involved in energy transduction
BG95_RS03135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BG95_RS03140	COG2176	DNA-directed DNA polymerase activity
BG95_RS03145	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BG95_RS03155	COG4717	serine-type aminopeptidase activity
BG95_RS03160	COG0528	UMP kinase activity
BG95_RS03165	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BG95_RS03170	COG1406	Chemotaxis phosphatase CheX
BG95_RS03175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BG95_RS03180	COG1181	Belongs to the D-alanine--D-alanine ligase family
BG95_RS03210	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BG95_RS03225	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BG95_RS03250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BG95_RS03255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BG95_RS03270	COG0436	Aminotransferase
BG95_RS03275	COG2045	Belongs to the ComB family
BG95_RS03285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BG95_RS03295	COG0105	UTP biosynthetic process
BG95_RS03305	COG3864	Putative metallopeptidase domain
BG95_RS03315	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BG95_RS03320	COG0151	Belongs to the GarS family
BG95_RS03325	COG0138	bifunctional purine biosynthesis protein purh
BG95_RS03330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BG95_RS03335	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BG95_RS03350	COG1132	(ABC) transporter
BG95_RS03355	COG0515	serine threonine protein kinase
BG95_RS03375	COG0840	transmembrane signaling receptor activity
BG95_RS03390	COG3833	ABC-type maltose transport systems, permease component
BG95_RS03395	COG1175	transmembrane transport
BG95_RS03405	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BG95_RS03420	COG0719	Fe-S assembly protein
BG95_RS03425	COG1137	ATPase activity
BG95_RS03455	COG1472	Belongs to the glycosyl hydrolase 3 family
BG95_RS03470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG95_RS03480	COG1879	ABC-type sugar transport system periplasmic component
BG95_RS03485	COG1172	Belongs to the binding-protein-dependent transport system permease family
BG95_RS03490	COG1129	ABC transporter
BG95_RS03495	COG1869	D-ribose catabolic process
BG95_RS03520	COG4948	Mandelate Racemase Muconate Lactonizing
BG95_RS03550	COG1328	CTP reductase activity
BG95_RS03595	COG1525	nuclease
BG95_RS03630	COG0579	oxidoreductase
BG95_RS03640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BG95_RS03665	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BG95_RS03670	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BG95_RS03675	COG0517	IMP dehydrogenase activity
BG95_RS03675	COG0516	GMP reductase activity
BG95_RS03680	COG0330	HflC and HflK could
BG95_RS03685	COG0330	HflC and HflK could
BG95_RS03690	COG1592	Rubrerythrin
BG95_RS03695	COG0751	glycine-tRNA ligase activity
BG95_RS03700	COG0752	glycyl-tRNA synthetase alpha subunit
BG95_RS03710	COG0772	Belongs to the SEDS family
BG95_RS03725	COG0360	Binds together with S18 to 16S ribosomal RNA
BG95_RS03730	COG0629	single-stranded DNA binding
BG95_RS03735	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BG95_RS03750	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BG95_RS03760	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BG95_RS03765	COG0250	Participates in transcription elongation, termination and antitermination
BG95_RS03770	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BG95_RS03775	COG0081	regulation of translation
BG95_RS03795	COG3706	GGDEF domain
BG95_RS03805	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BG95_RS03825	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BG95_RS03830	COG4659	FMN binding
BG95_RS03845	COG0489	protein tyrosine kinase activity
BG95_RS03845	COG3206	protein involved in exopolysaccharide biosynthesis
BG95_RS03850	COG1596	polysaccharide export
BG95_RS03860	COG0613	PHP domain protein
BG95_RS03865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BG95_RS03875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BG95_RS03880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BG95_RS03890	COG1706	bacterial-type flagellum-dependent cell motility
BG95_RS03895	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BG95_RS03900	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BG95_RS03905	COG0187	DNA topoisomerase II activity
BG95_RS03915	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BG95_RS03920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BG95_RS03925	COG0516	GMP reductase activity
BG95_RS03925	COG0517	IMP dehydrogenase activity
BG95_RS04100	COG0572	uridine kinase
BG95_RS04140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BG95_RS04150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BG95_RS04230	COG0501	Belongs to the peptidase M48B family
BG95_RS04260	COG0445	tRNA wobble uridine modification
BG95_RS04265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BG95_RS04270	COG1489	DNA binding
BG95_RS04285	COG0640	Transcriptional regulator
BG95_RS04290	COG0534	Mate efflux family protein
BG95_RS04295	COG0488	(ABC) transporter
BG95_RS04305	COG0489	protein tyrosine kinase activity
BG95_RS04315	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BG95_RS04320	COG0242	peptide deformylase activity
BG95_RS04325	COG0513	Belongs to the DEAD box helicase family
BG95_RS04335	COG1137	ATPase activity
BG95_RS04350	COG0745	RESPONSE REGULATOR receiver
BG95_RS04360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BG95_RS04370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BG95_RS04380	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BG95_RS04385	COG1684	flagellar biosynthetic protein fliR
BG95_RS04390	COG0840	transmembrane signaling receptor activity
BG95_RS04395	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BG95_RS04400	COG4869	propanediol catabolic process
BG95_RS04405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BG95_RS04425	COG0306	phosphate transporter
BG95_RS04430	COG0306	phosphate transporter
BG95_RS04435	COG1392	Phosphate transport regulator
BG95_RS04455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BG95_RS04460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BG95_RS04465	COG0504	CTP synthase activity
BG95_RS04470	COG1058	Belongs to the CinA family
BG95_RS04470	COG1546	Belongs to the CinA family
BG95_RS04500	COG1595	DNA-templated transcription, initiation
BG95_RS04515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BG95_RS04535	COG0366	Alpha amylase catalytic
BG95_RS04540	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BG95_RS04560	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BG95_RS04565	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BG95_RS04570	COG0384	phenazine biosynthesis protein PhzF
BG95_RS04575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BG95_RS04585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BG95_RS04600	COG1151	hydroxylamine reductase activity
BG95_RS04615	COG0395	ABC-type sugar transport system, permease component
BG95_RS04620	COG3345	alpha-galactosidase
BG95_RS04625	COG3300	MHYT domain
BG95_RS04625	COG5001	Diguanylate cyclase
BG95_RS04630	COG0840	transmembrane signaling receptor activity
BG95_RS04655	COG0124	histidyl-tRNA synthetase
BG95_RS04665	COG4565	transcriptional regulatory protein
BG95_RS04675	COG1131	(ABC) transporter
BG95_RS04685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BG95_RS04690	COG0366	Alpha amylase catalytic
BG95_RS04700	COG0840	transmembrane signaling receptor activity
BG95_RS04705	COG1410	methionine synthase
BG95_RS04705	COG0646	methionine synthase
BG95_RS04710	COG1476	TRANSCRIPTIONal
BG95_RS04725	COG0840	transmembrane signaling receptor activity
BG95_RS04730	COG3883	PFAM NLP P60 protein
BG95_RS04730	COG0791	NLP P60 protein
BG95_RS04740	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BG95_RS04750	COG1704	LemA family
BG95_RS04755	COG0519	Catalyzes the synthesis of GMP from XMP
BG95_RS04755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BG95_RS04765	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BG95_RS04770	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BG95_RS04780	COG0395	ABC-type sugar transport system, permease component
BG95_RS04785	COG1175	transmembrane transport
BG95_RS04795	COG1472	Belongs to the glycosyl hydrolase 3 family
BG95_RS04810	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BG95_RS04820	COG2217	Heavy metal translocating P-type atpase
BG95_RS04865	COG0438	transferase activity, transferring glycosyl groups
BG95_RS04865	COG0297	glycogen (starch) synthase activity
BG95_RS04890	COG0395	ABC-type sugar transport system, permease component
BG95_RS04895	COG1175	transmembrane transport
BG95_RS04910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BG95_RS04925	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BG95_RS04945	COG0072	phenylalanine-tRNA ligase activity
BG95_RS04945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG95_RS04950	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BG95_RS04955	COG1979	alcohol dehydrogenase
BG95_RS04960	COG0205	6-phosphofructokinase activity
BG95_RS04965	COG0651	ATP synthesis coupled electron transport
BG95_RS04970	COG1006	Multisubunit Na H antiporter MnhC subunit
BG95_RS04975	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BG95_RS04980	COG2199	diguanylate cyclase activity
BG95_RS04980	COG2203	Gaf domain
BG95_RS05000	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BG95_RS05005	COG1492	cobalamin metabolic process
BG95_RS05035	COG1187	pseudouridine synthase activity
BG95_RS05040	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BG95_RS05095	COG0628	permease
BG95_RS05125	COG1196	nuclear chromosome segregation
BG95_RS05135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BG95_RS05185	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BG95_RS05215	COG5012	cobalamin binding
BG95_RS05220	COG0084	hydrolase, TatD family'
BG95_RS05225	COG0632	four-way junction helicase activity
BG95_RS05255	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BG95_RS05265	COG0154	amidase activity
BG95_RS05270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BG95_RS05280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BG95_RS05285	COG0772	Belongs to the SEDS family
BG95_RS05295	COG3706	GGDEF domain
BG95_RS05300	COG0101	tRNA pseudouridine synthase activity
BG95_RS05310	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BG95_RS05320	COG0643	Histidine kinase
BG95_RS05320	COG2198	Histidine kinase
BG95_RS05325	COG0835	chemotaxis
BG95_RS05330	COG2201	protein-glutamate methylesterase activity
BG95_RS05340	COG1338	Plays a role in the flagellum-specific transport system
BG95_RS05345	COG1987	bacterial-type flagellum assembly
BG95_RS05350	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BG95_RS05355	COG0052	Belongs to the universal ribosomal protein uS2 family
BG95_RS05360	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BG95_RS05365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BG95_RS05370	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BG95_RS05390	COG0469	pyruvate kinase activity
BG95_RS05405	COG0564	pseudouridine synthase activity
BG95_RS05420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BG95_RS05425	COG0049	tRNA binding
BG95_RS05430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BG95_RS05435	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BG95_RS05440	COG0051	transcription antitermination factor activity, RNA binding
BG95_RS05445	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BG95_RS05450	COG0088	Forms part of the polypeptide exit tunnel
BG95_RS05455	COG0089	rRNA binding
BG95_RS05460	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BG95_RS05465	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BG95_RS05470	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BG95_RS05475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BG95_RS05480	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BG95_RS05485	COG0255	Belongs to the universal ribosomal protein uL29 family
BG95_RS05490	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BG95_RS05495	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BG95_RS05500	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BG95_RS05505	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BG95_RS05510	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BG95_RS05515	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BG95_RS05520	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BG95_RS05525	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BG95_RS05530	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BG95_RS05535	COG1841	ribosomal large subunit assembly
BG95_RS05540	COG0200	Binds to the 23S rRNA
BG95_RS05545	COG0201	protein transport
BG95_RS05550	COG0563	adenylate kinase activity
BG95_RS05560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BG95_RS05565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BG95_RS05570	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BG95_RS05575	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BG95_RS05580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BG95_RS05585	COG0202	RNA polymerase activity
BG95_RS05590	COG0203	ribosomal protein L17
BG95_RS05595	COG0544	peptidyl-prolyl cis-trans isomerase activity
BG95_RS05600	COG0740	serine-type endopeptidase activity
BG95_RS05605	COG0217	transcriptional regulatory protein
BG95_RS05615	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BG95_RS05620	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BG95_RS05625	COG0564	pseudouridine synthase activity
BG95_RS05630	COG0174	glutamine synthetase
BG95_RS05635	COG2342	PFAM TM1410 hypothetical-related protein
BG95_RS05650	COG0438	transferase activity, transferring glycosyl groups
BG95_RS05670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BG95_RS05670	COG2199	diguanylate cyclase activity
BG95_RS05680	COG1214	PFAM Peptidase M22, glycoprotease
BG95_RS05685	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BG95_RS05695	COG2078	PFAM AMMECR1 domain protein
BG95_RS05710	COG0037	tRNA processing
BG95_RS05715	COG3681	Belongs to the UPF0597 family
BG95_RS05725	COG1070	Carbohydrate kinase
BG95_RS05730	COG1509	lysine 2,3-aminomutase activity
BG95_RS05750	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BG95_RS05765	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BG95_RS05770	COG3481	metal-dependent phosphohydrolase, HD sub domain
BG95_RS05775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BG95_RS05785	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BG95_RS05795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BG95_RS05800	COG0358	DNA primase activity
BG95_RS05810	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BG95_RS05815	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BG95_RS05820	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BG95_RS05825	COG2868	ribosomal protein
BG95_RS05830	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BG95_RS05845	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BG95_RS05850	COG2176	DNA-directed DNA polymerase activity
BG95_RS05855	COG2359	stage V sporulation protein S
BG95_RS05865	COG3872	metal-dependent enzyme
BG95_RS05870	COG0019	diaminopimelate decarboxylase activity
BG95_RS05875	COG1473	amidohydrolase
BG95_RS05880	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BG95_RS05885	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BG95_RS05890	COG0012	GTP binding
BG95_RS05895	COG2052	Domain of unknown function (DUF370)
BG95_RS05900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BG95_RS05905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BG95_RS05925	COG0784	Response regulator, receiver
BG95_RS05925	COG3437	response regulator, receiver
BG95_RS05930	COG4191	Histidine kinase
BG95_RS05945	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BG95_RS05950	COG0085	RNA polymerase activity
BG95_RS05955	COG0222	ribosome binding
BG95_RS05960	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BG95_RS05970	COG0463	Glycosyl transferase, family 2
BG95_RS05970	COG0457	Tetratricopeptide repeat
BG95_RS05975	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BG95_RS05980	COG0305	Participates in initiation and elongation during chromosome replication
BG95_RS05990	COG0251	oxidation-reduction process
BG95_RS06000	COG2211	Major facilitator Superfamily
BG95_RS06005	COG1803	Methylglyoxal synthase
BG95_RS06010	COG0561	phosphatase activity
BG95_RS06020	COG0017	Asparaginyl-tRNA synthetase
BG95_RS06025	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BG95_RS06040	COG1469	GTP cyclohydrolase I activity
BG95_RS06050	COG0438	transferase activity, transferring glycosyl groups
BG95_RS06055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BG95_RS06060	COG0592	DNA-directed DNA polymerase activity
BG95_RS06065	COG4969	Belongs to the N-Me-Phe pilin family
BG95_RS06070	COG4555	ABC transporter
BG95_RS06095	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BG95_RS06115	COG1376	ErfK ybiS ycfS ynhG family protein
BG95_RS06120	COG1028	Short-chain dehydrogenase reductase Sdr
BG95_RS06135	COG0785	Cytochrome C biogenesis protein
BG95_RS06175	COG1516	flagellar protein fliS
BG95_RS06190	COG4608	Belongs to the ABC transporter superfamily
BG95_RS06195	COG0444	Belongs to the ABC transporter superfamily
BG95_RS06205	COG0601	transmembrane transport
BG95_RS06215	COG0742	ribosomal rna small subunit methyltransferase
BG95_RS06220	COG1177	transmembrane transport
BG95_RS06230	COG3842	ATPase activity
BG95_RS06235	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BG95_RS06240	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BG95_RS06245	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BG95_RS06255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BG95_RS06265	COG1811	Na channel or pump
BG95_RS06270	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BG95_RS06275	COG1480	7TM receptor with intracellular HD hydrolase
BG95_RS06280	COG1702	phosphate starvation-inducible protein PhoH
BG95_RS06290	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BG95_RS06290	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BG95_RS06295	COG5016	pyruvate
BG95_RS06295	COG0511	ligase activity, forming carbon-carbon bonds
BG95_RS06310	COG0346	lactoylglutathione lyase activity
BG95_RS06325	COG0653	protein targeting
BG95_RS06330	COG0850	regulation of cytokinetic process
BG95_RS06350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BG95_RS06370	COG1677	Flagellar hook-basal body complex protein FliE
BG95_RS06375	COG0071	Belongs to the small heat shock protein (HSP20) family
BG95_RS06380	COG0443	Heat shock 70 kDa protein
BG95_RS06385	COG0393	Putative heavy-metal-binding
BG95_RS06390	COG1073	alpha beta
BG95_RS06400	COG1131	(ABC) transporter
BG95_RS06405	COG1725	Transcriptional regulator
BG95_RS06410	COG0183	Belongs to the thiolase family
BG95_RS06420	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BG95_RS06425	COG0493	'glutamate synthase
BG95_RS06425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BG95_RS06430	COG0543	2 iron, 2 sulfur cluster binding
BG95_RS06460	COG2201	protein-glutamate methylesterase activity
BG95_RS06500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BG95_RS06505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BG95_RS06510	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BG95_RS06515	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BG95_RS06520	COG2137	regulation of response to DNA damage stimulus
BG95_RS06525	COG1418	mRNA catabolic process
BG95_RS06530	COG3842	ATPase activity
BG95_RS06545	COG1309	transcriptional regulator
BG95_RS06550	COG0254	rRNA binding
BG95_RS06555	COG1098	S1 RNA binding domain
BG95_RS06590	COG0483	inositol monophosphate 1-phosphatase activity
BG95_RS06595	COG0768	penicillin binding
BG95_RS06600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BG95_RS06620	COG1610	YqeY-like protein
BG95_RS06630	COG0698	ribose 5-phosphate isomerase
BG95_RS06635	COG1366	Belongs to the anti-sigma-factor antagonist family
BG95_RS06640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BG95_RS06645	COG1371	PFAM Archease protein family (DUF101 UPF0211)
BG95_RS06650	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BG95_RS06655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG95_RS06655	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BG95_RS06665	COG0601	transmembrane transport
BG95_RS06670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG95_RS06675	COG0444	Belongs to the ABC transporter superfamily
BG95_RS06680	COG4608	Belongs to the ABC transporter superfamily
BG95_RS06685	COG0540	Belongs to the ATCase OTCase family
BG95_RS06685	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BG95_RS06690	COG2199	diguanylate cyclase activity
BG95_RS06690	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BG95_RS06695	COG0735	belongs to the Fur family
BG95_RS06700	COG0450	alkyl hydroperoxide reductase
BG95_RS06705	COG1773	rubredoxin
BG95_RS06715	COG1528	Iron-storage protein
BG95_RS06725	COG2033	superoxide reductase activity
BG95_RS06740	COG1435	thymidine kinase activity
BG95_RS06745	COG0737	Belongs to the 5'-nucleotidase family
BG95_RS06755	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BG95_RS06760	COG1863	multisubunit Na H antiporter MnhE subunit
BG95_RS06765	COG2212	antiporter activity
BG95_RS06780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BG95_RS06780	COG2111	Na H antiporter
BG95_RS06785	COG1006	Multisubunit Na H antiporter MnhC subunit
BG95_RS06790	COG0651	ATP synthesis coupled electron transport
BG95_RS06795	COG0651	ATP synthesis coupled electron transport
BG95_RS06805	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BG95_RS06810	COG0649	NAD binding
BG95_RS06815	COG0649	NAD binding
BG95_RS06820	COG0493	'glutamate synthase
BG95_RS06860	COG0489	protein tyrosine kinase activity
BG95_RS06865	COG0446	pyridine nucleotide-disulphide oxidoreductase
BG95_RS06875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BG95_RS06885	COG1045	serine acetyltransferase
BG95_RS06895	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BG95_RS06900	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BG95_RS06905	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BG95_RS06910	COG0047	phosphoribosylformylglycinamidine synthase activity
BG95_RS06915	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BG95_RS06930	COG2313	pseudouridylate synthase activity
BG95_RS06935	COG0622	Phosphoesterase
BG95_RS06940	COG1739	Uncharacterized protein family UPF0029
BG95_RS06945	COG0436	Aminotransferase
BG95_RS06950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BG95_RS06955	COG0640	Transcriptional regulator
BG95_RS06970	COG0720	synthase
BG95_RS06975	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BG95_RS06980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BG95_RS07000	COG0149	triose-phosphate isomerase activity
BG95_RS07000	COG0126	phosphoglycerate kinase activity
BG95_RS07005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BG95_RS07020	COG1157	protein secretion by the type III secretion system
BG95_RS07030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BG95_RS07035	COG0191	fructose-bisphosphate aldolase activity
BG95_RS07055	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BG95_RS07060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BG95_RS07070	COG0233	cytoplasmic translational termination
BG95_RS07075	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BG95_RS07080	COG0575	Belongs to the CDS family
BG95_RS07085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BG95_RS07090	COG1077	Cell shape determining protein MreB Mrl
BG95_RS07105	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BG95_RS07125	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BG95_RS07150	COG1582	Flagellar protein (FlbD)
BG95_RS07160	COG1360	Flagellar Motor Protein
BG95_RS07170	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BG95_RS07175	COG1776	CheC inhibitor of MCP methylation
BG95_RS07175	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BG95_RS07180	COG0733	neurotransmitter:sodium symporter activity
BG95_RS07190	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BG95_RS07195	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BG95_RS07200	COG2239	Acts as a magnesium transporter
BG95_RS07210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BG95_RS07215	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BG95_RS07230	COG1120	ATPase activity
BG95_RS07235	COG0741	lytic transglycosylase activity
BG95_RS07250	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BG95_RS07255	COG1490	D-aminoacyl-tRNA deacylase activity
BG95_RS07260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BG95_RS07275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BG95_RS07275	COG2080	2 iron, 2 sulfur cluster binding
BG95_RS07280	COG2080	2 iron, 2 sulfur cluster binding
BG95_RS07300	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BG95_RS07315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BG95_RS07330	COG0330	HflC and HflK could
BG95_RS07340	COG3314	Sporulation integral membrane protein YlbJ
BG95_RS07345	COG0019	diaminopimelate decarboxylase activity
BG95_RS07360	COG0357	Ribosomal RNA small subunit methyltransferase G
BG95_RS07365	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BG95_RS07405	COG0584	glycerophosphoryl diester phosphodiesterase
BG95_RS07410	COG0156	8-amino-7-oxononanoate synthase activity
BG95_RS07415	COG1063	alcohol dehydrogenase
BG95_RS07420	COG0534	Mate efflux family protein
BG95_RS07430	COG1131	(ABC) transporter
BG95_RS07450	COG1027	Aspartate ammonia-lyase
BG95_RS07475	COG0572	uridine kinase
BG95_RS07480	COG1078	dGTPase activity
BG95_RS07485	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BG95_RS07495	COG1994	Peptidase M50
BG95_RS07510	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BG95_RS07515	COG1660	Displays ATPase and GTPase activities
BG95_RS07520	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BG95_RS07530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BG95_RS07535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BG95_RS07540	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BG95_RS07550	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BG95_RS07560	COG1132	(ABC) transporter
BG95_RS07575	COG0444	Belongs to the ABC transporter superfamily
BG95_RS07580	COG4608	Belongs to the ABC transporter superfamily
BG95_RS07590	COG0601	transmembrane transport
BG95_RS07595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BG95_RS07625	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BG95_RS07630	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BG95_RS07635	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BG95_RS07645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BG95_RS07650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BG95_RS07670	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BG95_RS07675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BG95_RS07675	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BG95_RS07695	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BG95_RS07700	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
BG95_RS07710	COG0735	belongs to the Fur family
BG95_RS07715	COG0195	Participates in both transcription termination and antitermination
BG95_RS07720	COG0779	Required for maturation of 30S ribosomal subunits
BG95_RS07745	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BG95_RS07750	COG1419	protein localization to endoplasmic reticulum
BG95_RS07770	COG1776	CheC inhibitor of MCP methylation
BG95_RS07775	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BG95_RS07780	COG1191	sigma factor activity
BG95_RS07810	COG3620	sequence-specific DNA binding
BG95_RS07810	COG0617	tRNA 3'-terminal CCA addition
BG95_RS07810	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BG95_RS07820	COG1234	tRNA 3'-trailer cleavage
BG95_RS07825	COG0359	binds to the 23S rRNA
BG95_RS07830	COG2890	protein-(glutamine-N5) methyltransferase activity
BG95_RS07835	COG2151	metal-sulfur cluster biosynthetic enzyme
BG95_RS07840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BG95_RS07845	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BG95_RS07855	COG0343	queuine tRNA-ribosyltransferase activity
BG95_RS07870	COG0730	response to heat
BG95_RS07875	COG1774	PSP1 C-terminal conserved region
BG95_RS07885	COG0802	atpase or kinase
BG95_RS07890	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BG95_RS07895	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BG95_RS07905	COG5002	protein histidine kinase activity
BG95_RS07910	COG1639	'signal transduction protein
BG95_RS07915	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BG95_RS07925	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BG95_RS07940	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BG95_RS07950	COG1162	GTPase activity
BG95_RS07955	COG1032	radical SAM domain protein
BG95_RS07980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BG95_RS07990	COG0557	exoribonuclease II activity
BG95_RS07995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BG95_RS07995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BG95_RS08000	COG2738	Putative neutral zinc metallopeptidase
BG95_RS08005	COG0745	RESPONSE REGULATOR receiver
BG95_RS08010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BG95_RS08015	COG3956	TIGRFAM MazG family protein
BG95_RS08020	COG0628	permease
BG95_RS08045	COG0587	DNA-directed DNA polymerase activity
BG95_RS08050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BG95_RS08055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BG95_RS08060	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BG95_RS08065	COG3706	GGDEF domain
BG95_RS08065	COG4251	negative regulation of phosphorylation
BG95_RS08065	COG5001	Diguanylate cyclase
BG95_RS08065	COG2203	Gaf domain
BG95_RS08070	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BG95_RS08075	COG1362	aminopeptidase activity
BG95_RS08100	COG1482	cell wall glycoprotein biosynthetic process
BG95_RS08110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BG95_RS08115	COG2255	four-way junction helicase activity
BG95_RS08120	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BG95_RS08130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BG95_RS08135	COG0704	Plays a role in the regulation of phosphate uptake
BG95_RS08145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BG95_RS08150	COG0138	bifunctional purine biosynthesis protein purh
BG95_RS08160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BG95_RS08170	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BG95_RS08175	COG2894	cell division
BG95_RS08200	COG0552	protein localization to endoplasmic reticulum
BG95_RS08215	COG1959	2 iron, 2 sulfur cluster binding
BG95_RS08220	COG0482	sulfurtransferase activity
BG95_RS08225	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BG95_RS08230	COG1316	TRANSCRIPTIONal
BG95_RS08235	COG1515	deoxyribonuclease V activity
BG95_RS08245	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BG95_RS08260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BG95_RS08265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BG95_RS08270	COG0157	Belongs to the NadC ModD family
BG95_RS08275	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BG95_RS08290	COG0366	Alpha amylase catalytic
BG95_RS08295	COG0840	transmembrane signaling receptor activity
BG95_RS08300	COG0517	IMP dehydrogenase activity
BG95_RS08300	COG0516	GMP reductase activity
BG95_RS08320	COG4657	Part of a membrane complex involved in electron transport
BG95_RS08325	COG4660	Part of a membrane complex involved in electron transport
BG95_RS08335	COG4658	electron transport chain
BG95_RS08340	COG4656	Part of a membrane complex involved in electron transport
BG95_RS08350	COG0525	valine-tRNA ligase activity
BG95_RS08355	COG0285	dihydrofolate synthase activity
BG95_RS08360	COG0799	negative regulation of ribosome biogenesis
BG95_RS08365	COG0402	S-adenosylhomocysteine deaminase activity
BG95_RS08370	COG1242	4 iron, 4 sulfur cluster binding
BG95_RS08375	COG4555	ABC transporter
BG95_RS08380	COG0842	Transport permease protein
BG95_RS08390	COG0641	radical SAM
BG95_RS08415	COG1132	(ABC) transporter
BG95_RS08440	COG1132	(ABC) transporter
BG95_RS08535	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
BG95_RS08550	COG0351	phosphomethylpyrimidine kinase
BG95_RS08550	COG1992	Thiamine-phosphate synthase
BG95_RS08555	COG0205	6-phosphofructokinase activity
BG95_RS08565	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BG95_RS08600	COG0571	ribonuclease III activity
BG95_RS08605	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BG95_RS08605	COG0519	Catalyzes the synthesis of GMP from XMP
BG95_RS08610	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BG95_RS08610	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BG95_RS08615	COG0728	peptidoglycan biosynthetic process
BG95_RS08620	COG2878	Part of a membrane complex involved in electron transport
BG95_RS08625	COG0758	DNA mediated transformation
BG95_RS08630	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BG95_RS08640	COG1185	polyribonucleotide nucleotidyltransferase activity
BG95_RS08645	COG0612	Peptidase, M16
BG95_RS08655	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BG95_RS08660	COG1175	transmembrane transport
BG95_RS08665	COG0395	ABC-type sugar transport system, permease component
BG95_RS08670	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BG95_RS08675	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BG95_RS08680	COG1366	Belongs to the anti-sigma-factor antagonist family
BG95_RS08685	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BG95_RS08690	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BG95_RS08695	COG1160	GTP binding
BG95_RS08700	COG1744	ABC transporter substrate-binding protein PnrA-like
BG95_RS08715	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BG95_RS08720	COG0594	ribonuclease P activity
BG95_RS08725	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BG95_RS08730	COG0706	membrane insertase activity
BG95_RS08735	COG1847	R3H domain protein
BG95_RS08750	COG0174	glutamine synthetase
BG95_RS08755	COG2203	Gaf domain
BG95_RS08755	COG2199	diguanylate cyclase activity
BG95_RS08765	COG2723	6-phospho-beta-galactosidase activity
BG95_RS08785	COG1496	oxidoreductase activity
BG95_RS08795	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BG95_RS08830	COG1454	alcohol dehydrogenase
BG95_RS08830	COG1012	belongs to the aldehyde dehydrogenase family
BG95_RS08845	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BG95_RS08875	COG1337	RAMP superfamily
BG95_RS08940	COG2373	Large extracellular alpha-helical protein
BG95_RS08950	COG3234	Protein of unknown function (DUF1175)
BG95_RS08965	COG0730	response to heat
BG95_RS08970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BG95_RS08995	COG3842	ATPase activity
BG95_RS09000	COG0438	transferase activity, transferring glycosyl groups