locus-tag	class	description
JYK00_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JYK00_RS00010	COG1141	Ferredoxin
JYK00_RS00015	COG1012	belongs to the aldehyde dehydrogenase family
JYK00_RS00025	COG1744	ABC transporter substrate-binding protein PnrA-like
JYK00_RS00030	COG3845	ABC transporter
JYK00_RS00035	COG4603	Belongs to the binding-protein-dependent transport system permease family
JYK00_RS00040	COG1079	Belongs to the binding-protein-dependent transport system permease family
JYK00_RS00050	COG1254	Belongs to the acylphosphatase family
JYK00_RS00080	COG2359	stage V sporulation protein S
JYK00_RS00085	COG0737	Belongs to the 5'-nucleotidase family
JYK00_RS00090	COG1132	(ABC) transporter
JYK00_RS00120	COG0301	tRNA thio-modification
JYK00_RS00135	COG4657	Part of a membrane complex involved in electron transport
JYK00_RS00140	COG4660	Part of a membrane complex involved in electron transport
JYK00_RS00150	COG4658	electron transport chain
JYK00_RS00155	COG4656	Part of a membrane complex involved in electron transport
JYK00_RS00165	COG0525	valine-tRNA ligase activity
JYK00_RS00170	COG0285	dihydrofolate synthase activity
JYK00_RS00175	COG0799	negative regulation of ribosome biogenesis
JYK00_RS00180	COG0402	S-adenosylhomocysteine deaminase activity
JYK00_RS00185	COG1242	4 iron, 4 sulfur cluster binding
JYK00_RS00200	COG4555	ABC transporter
JYK00_RS00215	COG0641	radical SAM
JYK00_RS00240	COG0793	Belongs to the peptidase S41A family
JYK00_RS00240	COG3409	Peptidoglycan-binding domain 1 protein
JYK00_RS00245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JYK00_RS00260	COG0497	DNA recombination
JYK00_RS00265	COG0295	cytidine deaminase activity
JYK00_RS00280	COG1162	GTPase activity
JYK00_RS00290	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JYK00_RS00295	COG0747	negative chemotaxis
JYK00_RS00300	COG0601	transmembrane transport
JYK00_RS00310	COG0444	Belongs to the ABC transporter superfamily
JYK00_RS00315	COG4608	Belongs to the ABC transporter superfamily
JYK00_RS00350	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JYK00_RS00355	COG2086	electron transfer activity
JYK00_RS00360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JYK00_RS00365	COG1333	cytochrome c biogenesis protein
JYK00_RS00380	COG1234	tRNA 3'-trailer cleavage
JYK00_RS00390	COG0446	pyridine nucleotide-disulphide oxidoreductase
JYK00_RS00395	COG0489	protein tyrosine kinase activity
JYK00_RS00415	COG1435	thymidine kinase activity
JYK00_RS00420	COG0737	Belongs to the 5'-nucleotidase family
JYK00_RS00430	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JYK00_RS00440	COG2212	antiporter activity
JYK00_RS00455	COG2111	Na H antiporter
JYK00_RS00455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JYK00_RS00465	COG0651	ATP synthesis coupled electron transport
JYK00_RS00470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JYK00_RS00470	COG2111	Na H antiporter
JYK00_RS00475	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JYK00_RS00480	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JYK00_RS00485	COG0649	NAD binding
JYK00_RS00490	COG0649	NAD binding
JYK00_RS00525	COG1131	(ABC) transporter
JYK00_RS00545	COG0039	L-malate dehydrogenase activity
JYK00_RS00560	COG1323	Belongs to the UPF0348 family
JYK00_RS00565	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JYK00_RS00575	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JYK00_RS00585	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JYK00_RS00605	COG0366	Alpha amylase catalytic
JYK00_RS00625	COG3039	Transposase
JYK00_RS00660	COG4555	ABC transporter
JYK00_RS00670	COG0592	DNA-directed DNA polymerase activity
JYK00_RS00675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JYK00_RS00680	COG0438	transferase activity, transferring glycosyl groups
JYK00_RS00690	COG1469	GTP cyclohydrolase I activity
JYK00_RS00705	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JYK00_RS00710	COG3345	alpha-galactosidase
JYK00_RS00715	COG1085	galactose-1-phosphate uridylyltransferase
JYK00_RS00720	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JYK00_RS00725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JYK00_RS00730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JYK00_RS00745	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JYK00_RS00755	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JYK00_RS00765	COG0803	Belongs to the bacterial solute-binding protein 9 family
JYK00_RS00770	COG1121	(ABC) transporter
JYK00_RS00775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JYK00_RS00785	COG3842	ATPase activity
JYK00_RS00805	COG0254	rRNA binding
JYK00_RS00810	COG1098	S1 RNA binding domain
JYK00_RS00845	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JYK00_RS00850	COG1307	EDD domain protein, DegV family
JYK00_RS00855	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JYK00_RS00860	COG0542	response to heat
JYK00_RS00870	COG4221	oxidoreductase activity
JYK00_RS00880	COG0840	transmembrane signaling receptor activity
JYK00_RS00885	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JYK00_RS00895	COG0840	transmembrane signaling receptor activity
JYK00_RS00905	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JYK00_RS00915	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JYK00_RS00915	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JYK00_RS00925	COG0235	Class ii aldolase
JYK00_RS00930	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JYK00_RS00930	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JYK00_RS00940	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JYK00_RS00965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JYK00_RS00970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JYK00_RS00975	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JYK00_RS00980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JYK00_RS00985	COG2137	regulation of response to DNA damage stimulus
JYK00_RS00990	COG1418	mRNA catabolic process
JYK00_RS00995	COG1677	Flagellar hook-basal body complex protein FliE
JYK00_RS01020	COG0850	regulation of cytokinetic process
JYK00_RS01025	COG0653	protein targeting
JYK00_RS01040	COG0346	lactoylglutathione lyase activity
JYK00_RS01045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JYK00_RS01055	COG0511	ligase activity, forming carbon-carbon bonds
JYK00_RS01075	COG1702	phosphate starvation-inducible protein PhoH
JYK00_RS01080	COG1480	7TM receptor with intracellular HD hydrolase
JYK00_RS01085	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JYK00_RS01100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JYK00_RS01125	COG1337	RAMP superfamily
JYK00_RS01140	COG0348	domain, Protein
JYK00_RS01150	COG2610	gluconate transmembrane transporter activity
JYK00_RS01155	COG2379	hydroxypyruvate reductase
JYK00_RS01170	COG4112	unkown
JYK00_RS01175	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JYK00_RS01180	COG1067	ATP-dependent peptidase activity
JYK00_RS01185	COG0180	Tryptophanyl-tRNA synthetase
JYK00_RS01190	COG0668	transmembrane transport
JYK00_RS01195	COG0840	transmembrane signaling receptor activity
JYK00_RS01200	COG3039	Transposase
JYK00_RS01205	COG3039	Transposase
JYK00_RS01230	COG0784	Response regulator, receiver
JYK00_RS01230	COG3437	response regulator, receiver
JYK00_RS01240	COG0357	Ribosomal RNA small subunit methyltransferase G
JYK00_RS01245	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JYK00_RS01250	COG1256	bacterial-type flagellum assembly
JYK00_RS01250	COG4786	Flagellar basal body rod
JYK00_RS01250	COG1256	bacterial-type flagellum assembly
JYK00_RS01250	COG4786	Flagellar basal body rod
JYK00_RS01270	COG3039	Transposase
JYK00_RS01290	COG1132	(ABC) transporter
JYK00_RS01305	COG1175	transmembrane transport
JYK00_RS01310	COG0395	ABC-type sugar transport system, permease component
JYK00_RS01320	COG1940	carbohydrate kinase activity
JYK00_RS01325	COG0395	ABC-type sugar transport system, permease component
JYK00_RS01330	COG1175	transmembrane transport
JYK00_RS01355	COG0483	inositol monophosphate 1-phosphatase activity
JYK00_RS01375	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JYK00_RS01395	COG0698	ribose 5-phosphate isomerase
JYK00_RS01400	COG1366	Belongs to the anti-sigma-factor antagonist family
JYK00_RS01405	COG1366	Belongs to the anti-sigma-factor antagonist family
JYK00_RS01410	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JYK00_RS01420	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JYK00_RS01425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYK00_RS01425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYK00_RS01430	COG2361	Protein of unknown function DUF86
JYK00_RS01445	COG2361	Protein of unknown function DUF86
JYK00_RS01460	COG1278	Cold shock
JYK00_RS01480	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
JYK00_RS01515	COG0411	ABC transporter
JYK00_RS01545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JYK00_RS01550	COG0750	zinc metalloprotease
JYK00_RS01555	COG0643	Histidine kinase
JYK00_RS01555	COG2198	Histidine kinase
JYK00_RS01560	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JYK00_RS01565	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JYK00_RS01570	COG0720	synthase
JYK00_RS01575	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JYK00_RS01580	COG1406	Chemotaxis phosphatase CheX
JYK00_RS01585	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JYK00_RS01590	COG0528	UMP kinase activity
JYK00_RS01595	COG4717	serine-type aminopeptidase activity
JYK00_RS01605	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JYK00_RS01610	COG2176	DNA-directed DNA polymerase activity
JYK00_RS01615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JYK00_RS01635	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JYK00_RS01640	COG0416	fatty acid biosynthetic process
JYK00_RS01645	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JYK00_RS01655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JYK00_RS01660	COG0765	amino acid transport
JYK00_RS01665	COG1126	abc transporter atp-binding protein
JYK00_RS01680	COG1131	(ABC) transporter
JYK00_RS01690	COG0569	domain protein
JYK00_RS01690	COG2985	domain, Protein
JYK00_RS01720	COG1706	bacterial-type flagellum-dependent cell motility
JYK00_RS01725	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JYK00_RS01730	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
JYK00_RS01735	COG0187	DNA topoisomerase II activity
JYK00_RS01745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JYK00_RS01750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JYK00_RS01755	COG0517	IMP dehydrogenase activity
JYK00_RS01755	COG0516	GMP reductase activity
JYK00_RS01765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JYK00_RS01790	COG1428	Deoxynucleoside kinase
JYK00_RS01795	COG1428	Deoxynucleoside kinase
JYK00_RS01800	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JYK00_RS01805	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JYK00_RS01815	COG0151	Belongs to the GarS family
JYK00_RS01820	COG0138	bifunctional purine biosynthesis protein purh
JYK00_RS01825	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JYK00_RS01830	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JYK00_RS01835	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JYK00_RS01840	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JYK00_RS01845	COG0047	phosphoribosylformylglycinamidine synthase activity
JYK00_RS01850	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JYK00_RS01855	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JYK00_RS01860	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JYK00_RS01865	COG0540	Belongs to the ATCase OTCase family
JYK00_RS01865	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
JYK00_RS01875	COG0543	2 iron, 2 sulfur cluster binding
JYK00_RS01880	COG0167	dihydroorotate dehydrogenase activity
JYK00_RS01895	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JYK00_RS01900	COG0085	RNA polymerase activity
JYK00_RS01905	COG0222	ribosome binding
JYK00_RS01910	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JYK00_RS01925	COG1187	pseudouridine synthase activity
JYK00_RS01930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JYK00_RS01940	COG1653	transport
JYK00_RS01945	COG1175	transmembrane transport
JYK00_RS01950	COG0395	ABC-type sugar transport system, permease component
JYK00_RS01955	COG0463	Glycosyl transferase, family 2
JYK00_RS01960	COG1737	Transcriptional regulator
JYK00_RS01970	COG3833	ABC-type maltose transport systems, permease component
JYK00_RS01975	COG1175	transmembrane transport
JYK00_RS01985	COG0542	response to heat
JYK00_RS02000	COG0410	ABC transporter
JYK00_RS02010	COG4177	L-phenylalanine transmembrane transporter activity
JYK00_RS02020	COG0683	leucine binding
JYK00_RS02040	COG1132	(ABC) transporter
JYK00_RS02085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JYK00_RS02090	COG2267	carboxylic ester hydrolase activity
JYK00_RS02095	COG1181	Belongs to the D-alanine--D-alanine ligase family
JYK00_RS02110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JYK00_RS02115	COG1045	serine acetyltransferase
JYK00_RS02120	COG2217	Heavy metal translocating P-type atpase
JYK00_RS02140	COG2078	PFAM AMMECR1 domain protein
JYK00_RS02150	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JYK00_RS02155	COG1214	PFAM Peptidase M22, glycoprotease
JYK00_RS02170	COG0174	glutamine synthetase
JYK00_RS02180	COG0521	Mo-molybdopterin cofactor biosynthetic process
JYK00_RS02190	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JYK00_RS02200	COG3842	ATPase activity
JYK00_RS02205	COG0725	ABC transporter, periplasmic molybdate-binding protein
JYK00_RS02210	COG0303	'Molybdopterin
JYK00_RS02215	COG3706	GGDEF domain
JYK00_RS02235	COG0081	regulation of translation
JYK00_RS02240	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JYK00_RS02245	COG0250	Participates in transcription elongation, termination and antitermination
JYK00_RS02250	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JYK00_RS02260	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JYK00_RS02275	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JYK00_RS02280	COG0629	single-stranded DNA binding
JYK00_RS02285	COG0360	Binds together with S18 to 16S ribosomal RNA
JYK00_RS02300	COG1881	PFAM PEBP family protein
JYK00_RS02305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JYK00_RS02310	COG0776	regulation of translation
JYK00_RS02320	COG0432	Pfam Uncharacterised protein family UPF0047
JYK00_RS02325	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JYK00_RS02335	COG1516	flagellar protein fliS
JYK00_RS02355	COG0251	oxidation-reduction process
JYK00_RS02365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JYK00_RS02375	COG2361	Protein of unknown function DUF86
JYK00_RS02380	COG0835	chemotaxis
JYK00_RS02385	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JYK00_RS02390	COG0542	response to heat
JYK00_RS02395	COG0772	Belongs to the SEDS family
JYK00_RS02405	COG0752	glycyl-tRNA synthetase alpha subunit
JYK00_RS02410	COG0751	glycine-tRNA ligase activity
JYK00_RS02415	COG1592	Rubrerythrin
JYK00_RS02420	COG2033	superoxide reductase activity
JYK00_RS02430	COG0330	HflC and HflK could
JYK00_RS02440	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JYK00_RS02450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JYK00_RS02455	COG2770	Histidine kinase
JYK00_RS02455	COG2208	phosphoserine phosphatase activity
JYK00_RS02460	COG0745	RESPONSE REGULATOR receiver
JYK00_RS02485	COG0513	Belongs to the DEAD box helicase family
JYK00_RS02490	COG0242	peptide deformylase activity
JYK00_RS02495	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JYK00_RS02505	COG0489	protein tyrosine kinase activity
JYK00_RS02510	COG0488	(ABC) transporter
JYK00_RS02515	COG1773	rubredoxin
JYK00_RS02515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JYK00_RS02530	COG0501	Belongs to the peptidase M48B family
JYK00_RS02550	COG2046	Belongs to the sulfate adenylyltransferase family
JYK00_RS02570	COG0613	PHP domain protein
JYK00_RS02575	COG0529	Catalyzes the synthesis of activated sulfate
JYK00_RS02585	COG0504	CTP synthase activity
JYK00_RS02590	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JYK00_RS02595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JYK00_RS02600	COG1496	oxidoreductase activity
JYK00_RS02605	COG0672	)-iron permease
JYK00_RS02615	COG0840	transmembrane signaling receptor activity
JYK00_RS02640	COG1595	DNA-templated transcription, initiation
JYK00_RS02655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JYK00_RS02670	COG0517	IMP dehydrogenase activity
JYK00_RS02670	COG0516	GMP reductase activity
JYK00_RS02705	COG1272	protein, Hemolysin III
JYK00_RS02805	COG2442	InterPro IPR007367
JYK00_RS02835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JYK00_RS02840	COG1216	Glycosyl transferase, family 2
JYK00_RS02850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JYK00_RS02880	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JYK00_RS02895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JYK00_RS02900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JYK00_RS02905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JYK00_RS02915	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JYK00_RS02925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JYK00_RS02935	COG3328	transposase activity
JYK00_RS02945	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
JYK00_RS02950	COG3039	Transposase
JYK00_RS02955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JYK00_RS02985	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JYK00_RS03040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JYK00_RS03045	COG1074	ATP-dependent DNA helicase activity
JYK00_RS03075	COG1598	PFAM Uncharacterised protein family UPF0150
JYK00_RS03100	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JYK00_RS03105	COG0456	acetyltransferase
JYK00_RS03110	COG0534	Mate efflux family protein
JYK00_RS03120	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JYK00_RS03140	COG1132	(ABC) transporter
JYK00_RS03170	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
JYK00_RS03185	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
JYK00_RS03200	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JYK00_RS03220	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JYK00_RS03225	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JYK00_RS03230	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JYK00_RS03235	COG0052	Belongs to the universal ribosomal protein uS2 family
JYK00_RS03240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JYK00_RS03245	COG1987	bacterial-type flagellum assembly
JYK00_RS03250	COG1338	Plays a role in the flagellum-specific transport system
JYK00_RS03260	COG2201	protein-glutamate methylesterase activity
JYK00_RS03265	COG0835	chemotaxis
JYK00_RS03270	COG0643	Histidine kinase
JYK00_RS03270	COG2198	Histidine kinase
JYK00_RS03280	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JYK00_RS03290	COG0101	tRNA pseudouridine synthase activity
JYK00_RS03300	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JYK00_RS03305	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JYK00_RS03310	COG4869	propanediol catabolic process
JYK00_RS03320	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JYK00_RS03330	COG1684	flagellar biosynthetic protein fliR
JYK00_RS03335	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JYK00_RS03340	COG1011	Hydrolase
JYK00_RS03350	COG0297	glycogen (starch) synthase activity
JYK00_RS03350	COG0438	transferase activity, transferring glycosyl groups
JYK00_RS03360	COG1215	transferase activity, transferring glycosyl groups
JYK00_RS03370	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JYK00_RS03380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JYK00_RS03385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JYK00_RS03415	COG0714	Associated with various cellular activities
JYK00_RS03425	COG0772	Belongs to the SEDS family
JYK00_RS03430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JYK00_RS03440	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JYK00_RS03445	COG0154	amidase activity
JYK00_RS03485	COG0632	four-way junction helicase activity
JYK00_RS03490	COG0084	hydrolase, TatD family'
JYK00_RS03505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JYK00_RS03505	COG3153	acetyltransferase
JYK00_RS03510	COG1032	radical SAM domain protein
JYK00_RS03515	COG2052	Domain of unknown function (DUF370)
JYK00_RS03525	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JYK00_RS03530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JYK00_RS03540	COG0019	diaminopimelate decarboxylase activity
JYK00_RS03545	COG1418	mRNA catabolic process
JYK00_RS03565	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JYK00_RS03570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JYK00_RS03575	COG1196	nuclear chromosome segregation
JYK00_RS03590	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JYK00_RS03605	COG0628	permease
JYK00_RS03620	COG3906	Belongs to the UPF0473 family
JYK00_RS03630	COG1979	alcohol dehydrogenase
JYK00_RS03635	COG0205	6-phosphofructokinase activity
JYK00_RS03640	COG0651	ATP synthesis coupled electron transport
JYK00_RS03645	COG2045	Belongs to the ComB family
JYK00_RS03650	COG1006	Multisubunit Na H antiporter MnhC subunit
JYK00_RS03665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JYK00_RS03665	COG0519	Catalyzes the synthesis of GMP from XMP
JYK00_RS03675	COG0561	phosphatase activity
JYK00_RS03685	COG0124	histidyl-tRNA synthetase
JYK00_RS03690	COG1131	(ABC) transporter
JYK00_RS03710	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JYK00_RS03730	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JYK00_RS03740	COG0367	asparagine synthase
JYK00_RS03755	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JYK00_RS03775	COG0457	Tetratricopeptide repeat
JYK00_RS03775	COG0463	Glycosyl transferase, family 2
JYK00_RS03800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JYK00_RS03815	COG1846	Transcriptional regulator
JYK00_RS03830	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JYK00_RS03835	COG0305	Participates in initiation and elongation during chromosome replication
JYK00_RS03845	COG0196	riboflavin kinase activity
JYK00_RS03850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JYK00_RS03865	COG2252	PERMEase
JYK00_RS03875	COG0450	alkyl hydroperoxide reductase
JYK00_RS03885	COG2033	superoxide reductase activity
JYK00_RS03900	COG2033	superoxide reductase activity
JYK00_RS03910	COG1523	belongs to the glycosyl hydrolase 13 family
JYK00_RS03915	COG2204	response regulator
JYK00_RS03920	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JYK00_RS03930	COG0697	spore germination
JYK00_RS03935	COG1077	Cell shape determining protein MreB Mrl
JYK00_RS03940	COG4786	Flagellar basal body rod
JYK00_RS03955	COG0445	tRNA wobble uridine modification
JYK00_RS03960	COG0469	pyruvate kinase activity
JYK00_RS03975	COG0564	pseudouridine synthase activity
JYK00_RS03990	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JYK00_RS03995	COG0049	tRNA binding
JYK00_RS04000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JYK00_RS04005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JYK00_RS04010	COG0051	transcription antitermination factor activity, RNA binding
JYK00_RS04015	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JYK00_RS04020	COG0088	Forms part of the polypeptide exit tunnel
JYK00_RS04025	COG0089	rRNA binding
JYK00_RS04030	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JYK00_RS04035	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JYK00_RS04040	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JYK00_RS04045	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JYK00_RS04050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JYK00_RS04055	COG0255	Belongs to the universal ribosomal protein uL29 family
JYK00_RS04060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JYK00_RS04065	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JYK00_RS04070	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JYK00_RS04075	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JYK00_RS04080	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JYK00_RS04085	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JYK00_RS04090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JYK00_RS04095	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JYK00_RS04100	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JYK00_RS04105	COG1841	ribosomal large subunit assembly
JYK00_RS04110	COG0200	Binds to the 23S rRNA
JYK00_RS04115	COG0201	protein transport
JYK00_RS04120	COG0563	adenylate kinase activity
JYK00_RS04125	COG0024	Methionine aminopeptidase
JYK00_RS04130	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JYK00_RS04135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JYK00_RS04140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JYK00_RS04145	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JYK00_RS04150	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JYK00_RS04155	COG0202	RNA polymerase activity
JYK00_RS04160	COG0203	ribosomal protein L17
JYK00_RS04165	COG0544	peptidyl-prolyl cis-trans isomerase activity
JYK00_RS04170	COG0740	serine-type endopeptidase activity
JYK00_RS04175	COG0217	transcriptional regulatory protein
JYK00_RS04185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JYK00_RS04190	COG0564	pseudouridine synthase activity
JYK00_RS04220	COG5012	cobalamin binding
JYK00_RS04235	COG1376	ErfK ybiS ycfS ynhG family protein
JYK00_RS04260	COG0785	Cytochrome C biogenesis protein
JYK00_RS04300	COG1175	transmembrane transport
JYK00_RS04305	COG0395	ABC-type sugar transport system, permease component
JYK00_RS04310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JYK00_RS04320	COG1131	(ABC) transporter
JYK00_RS04330	COG4565	transcriptional regulatory protein
JYK00_RS04340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JYK00_RS04345	COG1490	D-aminoacyl-tRNA deacylase activity
JYK00_RS04355	COG2172	sigma factor antagonist activity
JYK00_RS04370	COG1120	ATPase activity
JYK00_RS04390	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JYK00_RS04395	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JYK00_RS04405	COG2239	Acts as a magnesium transporter
JYK00_RS04415	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JYK00_RS04425	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JYK00_RS04425	COG1776	CheC inhibitor of MCP methylation
JYK00_RS04430	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JYK00_RS04440	COG1360	Flagellar Motor Protein
JYK00_RS04450	COG1582	Flagellar protein (FlbD)
JYK00_RS04455	COG1749	Flagellar hook protein flgE
JYK00_RS04475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JYK00_RS04480	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JYK00_RS04485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JYK00_RS04505	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JYK00_RS04510	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JYK00_RS04515	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JYK00_RS04525	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JYK00_RS04530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JYK00_RS04535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JYK00_RS04540	COG0527	aspartate kinase activity
JYK00_RS04545	COG2171	N-acyltransferase activity
JYK00_RS04550	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JYK00_RS04555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JYK00_RS04565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JYK00_RS04595	COG1337	RAMP superfamily
JYK00_RS04605	COG1353	crispr-associated protein
JYK00_RS04635	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JYK00_RS04640	COG1518	maintenance of DNA repeat elements
JYK00_RS04645	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JYK00_RS04690	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JYK00_RS04695	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JYK00_RS04710	COG0436	Aminotransferase
JYK00_RS04720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JYK00_RS04730	COG0105	UTP biosynthetic process
JYK00_RS04740	COG3864	Putative metallopeptidase domain
JYK00_RS04750	COG1058	Belongs to the CinA family
JYK00_RS04750	COG1546	Belongs to the CinA family
JYK00_RS04760	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JYK00_RS04765	COG0366	Alpha amylase catalytic
JYK00_RS04780	COG1131	(ABC) transporter
JYK00_RS04805	COG0739	heme binding
JYK00_RS04825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JYK00_RS04830	COG0037	tRNA processing
JYK00_RS04845	COG1968	undecaprenyl-diphosphatase activity
JYK00_RS04850	COG1228	amidohydrolase
JYK00_RS04865	COG0424	maF-like protein
JYK00_RS04870	COG2003	Belongs to the UPF0758 family
JYK00_RS04885	COG1215	transferase activity, transferring glycosyl groups
JYK00_RS04890	COG1215	transferase activity, transferring glycosyl groups
JYK00_RS04915	COG3409	Peptidoglycan-binding domain 1 protein
JYK00_RS04915	COG0793	Belongs to the peptidase S41A family
JYK00_RS04945	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JYK00_RS04950	COG0009	L-threonylcarbamoyladenylate synthase
JYK00_RS04960	COG0481	GTPase activity
JYK00_RS04965	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JYK00_RS04970	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JYK00_RS04975	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JYK00_RS04980	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JYK00_RS04990	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JYK00_RS04995	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JYK00_RS05000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JYK00_RS05005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JYK00_RS05010	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JYK00_RS05015	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JYK00_RS05020	COG0792	nuclease activity
JYK00_RS05025	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JYK00_RS05030	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JYK00_RS05035	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JYK00_RS05050	COG1461	Dihydroxyacetone kinase
JYK00_RS05060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JYK00_RS05065	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JYK00_RS05070	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JYK00_RS05080	COG0495	leucyl-tRNA aminoacylation
JYK00_RS05085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JYK00_RS05095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JYK00_RS05115	COG0561	phosphatase activity
JYK00_RS05125	COG0017	Asparaginyl-tRNA synthetase
JYK00_RS05130	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JYK00_RS05140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JYK00_RS05145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JYK00_RS05150	COG3872	metal-dependent enzyme
JYK00_RS05160	COG2359	stage V sporulation protein S
JYK00_RS05165	COG2176	DNA-directed DNA polymerase activity
JYK00_RS05170	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JYK00_RS05180	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JYK00_RS05190	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JYK00_RS05195	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JYK00_RS05200	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JYK00_RS05205	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JYK00_RS05210	COG0358	DNA primase activity
JYK00_RS05215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JYK00_RS05225	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JYK00_RS05240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JYK00_RS05245	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JYK00_RS05250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JYK00_RS05255	COG0095	Lipoate-protein ligase
JYK00_RS05270	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JYK00_RS05275	COG3852	Histidine kinase
JYK00_RS05280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JYK00_RS05295	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JYK00_RS05300	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JYK00_RS05305	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JYK00_RS05310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JYK00_RS05315	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JYK00_RS05320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JYK00_RS05325	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JYK00_RS05345	COG0006	proline dipeptidase activity
JYK00_RS05355	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JYK00_RS05360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JYK00_RS05360	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JYK00_RS05370	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JYK00_RS05375	COG0459	protein refolding
JYK00_RS05380	COG0396	ATPase activity
JYK00_RS05385	COG0719	Fe-S assembly protein
JYK00_RS05390	COG0719	Fe-S assembly protein
JYK00_RS05395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JYK00_RS05400	COG0822	iron-sulfur transferase activity
JYK00_RS05405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JYK00_RS05410	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JYK00_RS05415	COG3850	Histidine kinase
JYK00_RS05415	COG5002	protein histidine kinase activity
JYK00_RS05420	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JYK00_RS05430	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JYK00_RS05440	COG2313	pseudouridylate synthase activity
JYK00_RS05450	COG0622	Phosphoesterase
JYK00_RS05455	COG1739	Uncharacterized protein family UPF0029
JYK00_RS05460	COG0436	Aminotransferase
JYK00_RS05465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JYK00_RS05480	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JYK00_RS05480	COG2080	2 iron, 2 sulfur cluster binding
JYK00_RS05505	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JYK00_RS05520	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JYK00_RS05535	COG0330	HflC and HflK could
JYK00_RS05550	COG0019	diaminopimelate decarboxylase activity
JYK00_RS05565	COG0357	Ribosomal RNA small subunit methyltransferase G
JYK00_RS05570	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JYK00_RS05575	COG1937	Protein conserved in bacteria
JYK00_RS05585	COG1609	Transcriptional regulator
JYK00_RS05600	COG0395	ABC-type sugar transport system, permease component
JYK00_RS05605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JYK00_RS05610	COG1554	hydrolase, family 65, central catalytic
JYK00_RS05615	COG3039	Transposase
JYK00_RS05630	COG3706	GGDEF domain
JYK00_RS05655	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JYK00_RS05670	COG1785	Belongs to the alkaline phosphatase family
JYK00_RS05690	COG1477	protein flavinylation
JYK00_RS05695	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JYK00_RS05710	COG1157	protein secretion by the type III secretion system
JYK00_RS05720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JYK00_RS05725	COG0191	fructose-bisphosphate aldolase activity
JYK00_RS05745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JYK00_RS05750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JYK00_RS05760	COG0233	cytoplasmic translational termination
JYK00_RS05765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JYK00_RS05770	COG0575	Belongs to the CDS family
JYK00_RS05775	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JYK00_RS05780	COG1077	Cell shape determining protein MreB Mrl
JYK00_RS05795	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JYK00_RS05820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JYK00_RS05830	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JYK00_RS05850	COG0072	phenylalanine-tRNA ligase activity
JYK00_RS05850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JYK00_RS05855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JYK00_RS05875	COG1725	Transcriptional regulator
JYK00_RS05880	COG1131	(ABC) transporter
JYK00_RS05885	COG1073	alpha beta
JYK00_RS05895	COG0393	Putative heavy-metal-binding
JYK00_RS05900	COG0443	Heat shock 70 kDa protein
JYK00_RS05920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JYK00_RS05945	COG0493	'glutamate synthase
JYK00_RS05945	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JYK00_RS05950	COG0543	2 iron, 2 sulfur cluster binding
JYK00_RS05955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JYK00_RS06010	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JYK00_RS06015	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JYK00_RS06030	COG2030	dehydratase
JYK00_RS06035	COG1509	lysine 2,3-aminomutase activity
JYK00_RS06040	COG0604	alcohol dehydrogenase
JYK00_RS06045	COG3246	L-lysine catabolic process to acetate
JYK00_RS06050	COG1607	acyl-coa hydrolase
JYK00_RS06060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JYK00_RS06065	COG0739	heme binding
JYK00_RS06070	COG2264	protein methyltransferase activity
JYK00_RS06080	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JYK00_RS06085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JYK00_RS06095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JYK00_RS06100	COG1993	acr, cog1993
JYK00_RS06105	COG0116	Belongs to the methyltransferase superfamily
JYK00_RS06110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JYK00_RS06120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JYK00_RS06125	COG0497	DNA recombination
JYK00_RS06135	COG0148	phosphopyruvate hydratase activity
JYK00_RS06140	COG4974	Belongs to the 'phage' integrase family
JYK00_RS06145	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JYK00_RS06155	COG0193	aminoacyl-tRNA hydrolase activity
JYK00_RS06160	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JYK00_RS06165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JYK00_RS06170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JYK00_RS06180	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JYK00_RS06180	COG0574	Belongs to the PEP-utilizing enzyme family
JYK00_RS06185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JYK00_RS06195	COG1027	Aspartate ammonia-lyase
JYK00_RS06200	COG1160	GTP binding
JYK00_RS06210	COG0142	geranyltranstransferase activity
JYK00_RS06220	COG0572	uridine kinase
JYK00_RS06225	COG1078	dGTPase activity
JYK00_RS06230	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JYK00_RS06240	COG1994	Peptidase M50
JYK00_RS06255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JYK00_RS06260	COG1660	Displays ATPase and GTPase activities
JYK00_RS06265	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JYK00_RS06270	COG1481	regulation of sporulation
JYK00_RS06275	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JYK00_RS06280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JYK00_RS06285	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JYK00_RS06295	COG1164	Oligoendopeptidase f
JYK00_RS06300	COG0534	Mate efflux family protein
JYK00_RS06305	COG0667	Aldo Keto reductase
JYK00_RS06320	COG1131	(ABC) transporter
JYK00_RS06330	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JYK00_RS06330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JYK00_RS06335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JYK00_RS06335	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JYK00_RS06340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JYK00_RS06350	COG1573	uracil-dna glycosylase
JYK00_RS06385	COG1132	(ABC) transporter
JYK00_RS06420	COG1063	alcohol dehydrogenase
JYK00_RS06425	COG0156	8-amino-7-oxononanoate synthase activity
JYK00_RS06440	COG2217	Heavy metal translocating P-type atpase
JYK00_RS06460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JYK00_RS06465	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JYK00_RS06470	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JYK00_RS06475	COG1956	GAF domain-containing protein
JYK00_RS06480	COG3706	GGDEF domain
JYK00_RS06485	COG1132	(ABC) transporter
JYK00_RS06500	COG0444	Belongs to the ABC transporter superfamily
JYK00_RS06505	COG4608	Belongs to the ABC transporter superfamily
JYK00_RS06510	COG0747	negative chemotaxis
JYK00_RS06515	COG0601	transmembrane transport
JYK00_RS06520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JYK00_RS06545	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JYK00_RS06555	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JYK00_RS06560	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JYK00_RS06565	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JYK00_RS06575	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JYK00_RS06580	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JYK00_RS06600	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JYK00_RS06610	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JYK00_RS06610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JYK00_RS06630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JYK00_RS06635	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
JYK00_RS06645	COG0735	belongs to the Fur family
JYK00_RS06650	COG0195	Participates in both transcription termination and antitermination
JYK00_RS06655	COG0779	Required for maturation of 30S ribosomal subunits
JYK00_RS06680	COG0556	nucleotide-excision repair
JYK00_RS06685	COG3706	GGDEF domain
JYK00_RS06690	COG0237	dephospho-CoA kinase activity
JYK00_RS06700	COG0166	Belongs to the GPI family
JYK00_RS06705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JYK00_RS06720	COG5002	protein histidine kinase activity
JYK00_RS06725	COG0745	RESPONSE REGULATOR receiver
JYK00_RS06730	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
JYK00_RS06735	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JYK00_RS06740	COG1105	Belongs to the carbohydrate kinase PfkB family
JYK00_RS06755	COG1309	transcriptional regulator
JYK00_RS06760	COG0427	acetyl-CoA hydrolase
JYK00_RS06765	COG0183	Belongs to the thiolase family
JYK00_RS06770	COG1028	Short-chain dehydrogenase reductase Sdr
JYK00_RS06795	COG2267	carboxylic ester hydrolase activity
JYK00_RS06800	COG0446	pyridine nucleotide-disulphide oxidoreductase
JYK00_RS06810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JYK00_RS06820	COG1879	ABC-type sugar transport system periplasmic component
JYK00_RS06825	COG1172	Belongs to the binding-protein-dependent transport system permease family
JYK00_RS06830	COG1129	ABC transporter
JYK00_RS06835	COG1869	D-ribose catabolic process
JYK00_RS06840	COG0456	acetyltransferase
JYK00_RS06855	COG0733	neurotransmitter:sodium symporter activity
JYK00_RS06865	COG0628	permease
JYK00_RS06870	COG0606	chelatase, subunit chli
JYK00_RS06875	COG3956	TIGRFAM MazG family protein
JYK00_RS06880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JYK00_RS06885	COG0745	RESPONSE REGULATOR receiver
JYK00_RS06900	COG0557	exoribonuclease II activity
JYK00_RS06910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JYK00_RS06920	COG0704	Plays a role in the regulation of phosphate uptake
JYK00_RS06925	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JYK00_RS06935	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JYK00_RS06940	COG2255	four-way junction helicase activity
JYK00_RS06950	COG1268	BioY protein
JYK00_RS06955	COG2070	2-Nitropropane dioxygenase
JYK00_RS06960	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JYK00_RS06965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JYK00_RS06975	COG1187	pseudouridine synthase activity
JYK00_RS07000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JYK00_RS07005	COG0126	phosphoglycerate kinase activity
JYK00_RS07010	COG0149	triose-phosphate isomerase activity
JYK00_RS07010	COG0126	phosphoglycerate kinase activity
JYK00_RS07020	COG0569	domain protein
JYK00_RS07025	COG0475	glutathione-regulated potassium exporter activity
JYK00_RS07025	COG0569	domain protein
JYK00_RS07075	COG1335	isochorismatase
JYK00_RS07080	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JYK00_RS07085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JYK00_RS07095	COG1564	THIamine pyrophosphokinase
JYK00_RS07100	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JYK00_RS07105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JYK00_RS07110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JYK00_RS07120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JYK00_RS07135	COG3039	Transposase
JYK00_RS07140	COG0205	6-phosphofructokinase activity
JYK00_RS07145	COG1574	metal-dependent hydrolase with the TIM-barrel fold
JYK00_RS07165	COG0517	IMP dehydrogenase activity
JYK00_RS07165	COG0516	GMP reductase activity
JYK00_RS07170	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JYK00_RS07175	COG0778	Nitroreductase
JYK00_RS07180	COG0840	transmembrane signaling receptor activity
JYK00_RS07190	COG2226	methyltransferase
JYK00_RS07195	COG0697	spore germination
JYK00_RS07205	COG1151	hydroxylamine reductase activity
JYK00_RS07210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JYK00_RS07215	COG0174	glutamine synthetase
JYK00_RS07225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JYK00_RS07225	COG0475	glutathione-regulated potassium exporter activity
JYK00_RS07240	COG0706	membrane insertase activity
JYK00_RS07245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JYK00_RS07255	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JYK00_RS07260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JYK00_RS07275	COG1917	Cupin 2, conserved barrel domain protein
JYK00_RS07275	COG4977	sequence-specific DNA binding
JYK00_RS07285	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JYK00_RS07305	COG3706	GGDEF domain
JYK00_RS07320	COG3039	Transposase
JYK00_RS07325	COG3328	transposase activity
JYK00_RS07340	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JYK00_RS07355	COG3234	Protein of unknown function (DUF1175)
JYK00_RS07365	COG2373	Large extracellular alpha-helical protein
JYK00_RS07395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JYK00_RS07405	COG1410	methionine synthase
JYK00_RS07405	COG0646	methionine synthase
JYK00_RS07435	COG3842	ATPase activity
JYK00_RS07440	COG0438	transferase activity, transferring glycosyl groups
JYK00_RS07455	COG3118	belongs to the thioredoxin family
JYK00_RS07455	COG0492	ferredoxin-NADP+ reductase activity
JYK00_RS07460	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JYK00_RS07575	COG1401	restriction endodeoxyribonuclease activity
JYK00_RS07600	COG4608	Belongs to the ABC transporter superfamily
JYK00_RS07605	COG0444	Belongs to the ABC transporter superfamily
JYK00_RS07610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JYK00_RS07615	COG0601	transmembrane transport
JYK00_RS07645	COG1363	Peptidase, m42
JYK00_RS07660	COG1247	-acetyltransferase
JYK00_RS07680	COG2986	histidine ammonia-lyase
JYK00_RS07690	COG0268	Binds directly to 16S ribosomal RNA
JYK00_RS07695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JYK00_RS07710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JYK00_RS07715	COG1923	regulation of RNA biosynthetic process
JYK00_RS07730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JYK00_RS07735	COG1530	ribonuclease E activity
JYK00_RS07745	COG1013	pyruvate-flavodoxin oxidoreductase activity
JYK00_RS07760	COG2201	protein-glutamate methylesterase activity
JYK00_RS07765	COG0497	DNA recombination
JYK00_RS07770	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JYK00_RS07775	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JYK00_RS07775	COG0646	methionine synthase
JYK00_RS07810	COG2813	Specifically methylates the guanine in position
JYK00_RS07815	COG1122	ATPase activity
JYK00_RS07820	COG1459	type II secretion system
JYK00_RS07850	COG1450	Type ii and iii secretion system protein
JYK00_RS07855	COG1355	regulation of microtubule-based process
JYK00_RS07860	COG1596	polysaccharide export
JYK00_RS07860	COG1555	photosystem II stabilization
JYK00_RS07865	COG0768	penicillin binding
JYK00_RS07875	COG0275	rRNA processing
JYK00_RS07895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JYK00_RS07905	COG4608	Belongs to the ABC transporter superfamily
JYK00_RS07910	COG0444	Belongs to the ABC transporter superfamily
JYK00_RS07915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JYK00_RS07920	COG0601	transmembrane transport
JYK00_RS07925	COG0322	excinuclease ABC activity
JYK00_RS07935	COG0509	glycine decarboxylation via glycine cleavage system
JYK00_RS07940	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
JYK00_RS07940	COG1918	ferrous iron import across plasma membrane
JYK00_RS07955	COG1744	ABC transporter substrate-binding protein PnrA-like
JYK00_RS07960	COG1160	GTP binding
JYK00_RS07970	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JYK00_RS07975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JYK00_RS07980	COG1366	Belongs to the anti-sigma-factor antagonist family
JYK00_RS07985	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JYK00_RS07990	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JYK00_RS07995	COG0395	ABC-type sugar transport system, permease component
JYK00_RS08000	COG1175	transmembrane transport
JYK00_RS08005	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JYK00_RS08015	COG0612	Peptidase, M16
JYK00_RS08020	COG1185	polyribonucleotide nucleotidyltransferase activity
JYK00_RS08030	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JYK00_RS08035	COG0758	DNA mediated transformation
JYK00_RS08040	COG2878	Part of a membrane complex involved in electron transport
JYK00_RS08045	COG0728	peptidoglycan biosynthetic process
JYK00_RS08050	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JYK00_RS08050	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JYK00_RS08060	COG0571	ribonuclease III activity
JYK00_RS08085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JYK00_RS08095	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JYK00_RS08100	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JYK00_RS08110	COG0626	cystathionine gamma-synthase activity
JYK00_RS08140	COG1309	transcriptional regulator
JYK00_RS08145	COG0582	viral genome integration into host DNA
JYK00_RS08160	COG1609	Transcriptional regulator
JYK00_RS08165	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
JYK00_RS08170	COG0395	ABC-type sugar transport system, permease component
JYK00_RS08175	COG1175	transmembrane transport
JYK00_RS08195	COG0840	transmembrane signaling receptor activity
JYK00_RS08205	COG1178	ABC-type Fe3 transport system permease component
JYK00_RS08210	COG0058	SHG alpha-glucan phosphorylase activity
JYK00_RS08215	COG1509	lysine 2,3-aminomutase activity
JYK00_RS08235	COG2270	Major facilitator Superfamily
JYK00_RS08240	COG1773	rubredoxin
JYK00_RS08245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JYK00_RS08255	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JYK00_RS08260	COG1196	nuclear chromosome segregation
JYK00_RS08260	COG0741	lytic transglycosylase activity
JYK00_RS08260	COG0739	heme binding
JYK00_RS08265	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JYK00_RS08265	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JYK00_RS08275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JYK00_RS08280	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JYK00_RS08295	COG0840	transmembrane signaling receptor activity
JYK00_RS08305	COG3681	Belongs to the UPF0597 family
JYK00_RS08320	COG1760	l-serine dehydratase
JYK00_RS08330	COG1543	Belongs to the glycosyl hydrolase 57 family
JYK00_RS08335	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JYK00_RS08340	COG1144	Oxidoreductase
JYK00_RS08345	COG0674	pyruvate-flavodoxin oxidoreductase activity
JYK00_RS08350	COG1013	pyruvate-flavodoxin oxidoreductase activity
JYK00_RS08365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JYK00_RS08370	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JYK00_RS08380	COG0402	S-adenosylhomocysteine deaminase activity
JYK00_RS08385	COG0167	dihydroorotate dehydrogenase activity
JYK00_RS08390	COG3706	GGDEF domain
JYK00_RS08395	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JYK00_RS08405	COG0312	modulator of DNA gyrase
JYK00_RS08410	COG0312	modulator of DNA gyrase
JYK00_RS08415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JYK00_RS08420	COG0587	DNA-directed DNA polymerase activity
JYK00_RS08440	COG1489	DNA binding
JYK00_RS08445	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JYK00_RS08450	COG0228	four-way junction DNA binding
JYK00_RS08455	COG1837	Belongs to the UPF0109 family
JYK00_RS08460	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JYK00_RS08465	COG0336	Belongs to the RNA methyltransferase TrmD family
JYK00_RS08470	COG4752	Belongs to the RNA methyltransferase TrmD family
JYK00_RS08475	COG0335	large ribosomal subunit rRNA binding
JYK00_RS08480	COG0681	Belongs to the peptidase S26 family
JYK00_RS08525	COG4948	Mandelate Racemase Muconate Lactonizing
JYK00_RS08575	COG0840	transmembrane signaling receptor activity
JYK00_RS08580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JYK00_RS08595	COG0395	ABC-type sugar transport system, permease component
JYK00_RS08610	COG1392	Phosphate transport regulator
JYK00_RS08615	COG0306	phosphate transporter
JYK00_RS08630	COG0154	amidase activity
JYK00_RS08645	COG1653	transport
JYK00_RS08650	COG0438	transferase activity, transferring glycosyl groups
JYK00_RS08660	COG5002	protein histidine kinase activity
JYK00_RS08665	COG0745	RESPONSE REGULATOR receiver
JYK00_RS08670	COG0704	Plays a role in the regulation of phosphate uptake
JYK00_RS08675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JYK00_RS08680	COG0581	inorganic phosphate transmembrane transporter activity
JYK00_RS08715	COG1758	RNA polymerase activity
JYK00_RS08720	COG0194	GDP metabolic process
JYK00_RS08725	COG2052	Domain of unknown function (DUF370)
JYK00_RS08760	COG3426	butyrate kinase activity
JYK00_RS08765	COG0280	phosphate acetyltransferase
JYK00_RS08770	COG3426	butyrate kinase activity
JYK00_RS08775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JYK00_RS08780	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JYK00_RS08785	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JYK00_RS08800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JYK00_RS08810	COG1482	cell wall glycoprotein biosynthetic process
JYK00_RS08830	COG1846	Transcriptional regulator
JYK00_RS08835	COG1362	aminopeptidase activity
JYK00_RS08840	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JYK00_RS08845	COG3706	GGDEF domain
JYK00_RS08855	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JYK00_RS08870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JYK00_RS08875	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JYK00_RS08885	COG0730	response to heat
JYK00_RS08890	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JYK00_RS08900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JYK00_RS08905	COG1639	'signal transduction protein
JYK00_RS08915	COG0018	arginyl-trna synthetase
JYK00_RS08920	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JYK00_RS08925	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JYK00_RS08930	COG0802	atpase or kinase
JYK00_RS08940	COG1774	PSP1 C-terminal conserved region
JYK00_RS08960	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JYK00_RS08965	COG1419	protein localization to endoplasmic reticulum
JYK00_RS08985	COG1776	CheC inhibitor of MCP methylation
JYK00_RS08990	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
JYK00_RS09030	COG3620	sequence-specific DNA binding
JYK00_RS09030	COG0617	tRNA 3'-terminal CCA addition
JYK00_RS09030	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JYK00_RS09045	COG0359	binds to the 23S rRNA
JYK00_RS09050	COG2890	protein-(glutamine-N5) methyltransferase activity
JYK00_RS09055	COG2151	metal-sulfur cluster biosynthetic enzyme
JYK00_RS09060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JYK00_RS09070	COG0343	queuine tRNA-ribosyltransferase activity
JYK00_RS09090	COG0442	prolyl-tRNA aminoacylation
JYK00_RS09095	COG0215	cysteine-tRNA ligase activity
JYK00_RS09100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JYK00_RS09110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JYK00_RS09115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JYK00_RS09120	COG1335	isochorismatase
JYK00_RS09125	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JYK00_RS09145	COG0297	glycogen (starch) synthase activity
JYK00_RS09155	COG3829	transcription factor binding
JYK00_RS09155	COG3290	protein histidine kinase activity
JYK00_RS09165	COG1181	Belongs to the D-alanine--D-alanine ligase family
JYK00_RS09185	COG0306	phosphate transporter
JYK00_RS09190	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JYK00_RS09195	COG0484	heat shock protein binding
JYK00_RS09200	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JYK00_RS09215	COG0383	alpha-mannosidase activity
JYK00_RS09220	COG1032	radical SAM domain protein
JYK00_RS09230	COG0138	bifunctional purine biosynthesis protein purh
JYK00_RS09240	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JYK00_RS09250	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JYK00_RS09255	COG2894	cell division
JYK00_RS09280	COG0552	protein localization to endoplasmic reticulum
JYK00_RS09290	COG3584	3D domain protein
JYK00_RS09295	COG1959	2 iron, 2 sulfur cluster binding
JYK00_RS09300	COG0482	sulfurtransferase activity
JYK00_RS09305	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JYK00_RS09310	COG1316	TRANSCRIPTIONal
JYK00_RS09315	COG1515	deoxyribonuclease V activity
JYK00_RS09320	COG2226	methyltransferase
JYK00_RS09335	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JYK00_RS09370	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JYK00_RS09380	COG1028	Short-chain dehydrogenase reductase Sdr
JYK00_RS09385	COG0572	uridine kinase
JYK00_RS09395	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JYK00_RS09415	COG1132	(ABC) transporter
JYK00_RS09420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JYK00_RS09425	COG0351	phosphomethylpyrimidine kinase
JYK00_RS09425	COG1992	Thiamine-phosphate synthase
JYK00_RS09430	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JYK00_RS09460	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JYK00_RS09505	COG0477	Major facilitator Superfamily
JYK00_RS09510	COG1827	regulation of RNA biosynthetic process
JYK00_RS09515	COG0116	Belongs to the methyltransferase superfamily
JYK00_RS09515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JYK00_RS09520	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JYK00_RS09525	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JYK00_RS09530	COG1396	sequence-specific DNA binding
JYK00_RS09530	COG1917	Cupin 2, conserved barrel domain protein
JYK00_RS09535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JYK00_RS09545	COG1811	Na channel or pump
JYK00_RS09555	COG0840	transmembrane signaling receptor activity
JYK00_RS09570	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JYK00_RS09570	COG0674	pyruvate-flavodoxin oxidoreductase activity
JYK00_RS09580	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JYK00_RS09590	COG1122	ATPase activity
JYK00_RS09595	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
JYK00_RS09600	COG0205	6-phosphofructokinase activity
JYK00_RS09605	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
JYK00_RS09610	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JYK00_RS09615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JYK00_RS09620	COG1862	Preprotein translocase
JYK00_RS09625	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JYK00_RS09635	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
JYK00_RS09640	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JYK00_RS09655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JYK00_RS09670	COG1570	exodeoxyribonuclease VII activity
JYK00_RS09675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JYK00_RS09675	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JYK00_RS09690	COG1193	negative regulation of DNA recombination
JYK00_RS09700	COG0306	phosphate transporter
JYK00_RS09725	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JYK00_RS09735	COG0549	Belongs to the carbamate kinase family
JYK00_RS09740	COG0280	phosphate acetyltransferase