locus-tag	class	description
G4V39_RS00025	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
G4V39_RS00040	ENOG4105D05	Receptor
G4V39_RS00060	ENOG4105M3Z	response regulator
G4V39_RS00065	ENOG4105BZU	Histidine kinase
G4V39_RS00070	ENOG4105BZU	Histidine kinase
G4V39_RS00080	ENOG4105ENE	Histidine kinase
G4V39_RS00085	ENOG4105WH1	Two component transcriptional regulator luxr family
G4V39_RS00095	ENOG4105DTS	flagellar hook-associated
G4V39_RS00110	ENOG4105I03	Flagellin
G4V39_RS00115	ENOG4107TVC	Glycosyl transferase, family 2
G4V39_RS00120	ENOG4105J5G	Transferase hexapeptide repeat containing protein
G4V39_RS00130	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G4V39_RS00135	ENOG4105CAQ	asparagine synthetase
G4V39_RS00165	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
G4V39_RS00170	ENOG4105D6A	Electron transport complex
G4V39_RS00180	ENOG4105DZB	Electron transport complex
G4V39_RS00185	ENOG4105DGN	Electron transport complex
G4V39_RS00195	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
G4V39_RS00205	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G4V39_RS00210	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G4V39_RS00215	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G4V39_RS00220	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G4V39_RS00225	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
G4V39_RS00230	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G4V39_RS00240	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G4V39_RS00250	ENOG4105C8S	subunit m
G4V39_RS00255	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G4V39_RS00285	ENOG4105C8M	UPF0272 protein
G4V39_RS00290	ENOG4108ZAI	phosphatidylglycerophosphatase a
G4V39_RS00295	ENOG4105W49	UPF0434 protein
G4V39_RS00300	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
G4V39_RS00305	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
G4V39_RS00310	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
G4V39_RS00320	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G4V39_RS00325	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
G4V39_RS00330	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
G4V39_RS00340	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
G4V39_RS00345	ENOG4105C1A	potassium transporter peripheral membrane
G4V39_RS00350	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
G4V39_RS00355	ENOG4105DFU	Cell wall formation (By similarity)
G4V39_RS00360	ENOG4105K4P	CoA-binding domain protein
G4V39_RS00375	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
G4V39_RS00380	ENOG4105CDY	transcriptional regulatory protein
G4V39_RS00385	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
G4V39_RS00395	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G4V39_RS00400	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
G4V39_RS00405	ENOG410801I	Peptidyl-prolyl cis-trans isomerase
G4V39_RS00415	ENOG4105DJ0	Poly(A) Polymerase
G4V39_RS00420	ENOG4108JUA	Transcriptional regulator
G4V39_RS00440	ENOG4105D05	Receptor
G4V39_RS00445	ENOG4105DC7	peptidase M24
G4V39_RS00455	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
G4V39_RS00460	ENOG4108Z03	MAF-like protein
G4V39_RS00465	ENOG4105F8V	Hydrolase, tatD family
G4V39_RS00485	ENOG41080TK	Universal stress protein
G4V39_RS00490	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G4V39_RS00495	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
G4V39_RS00500	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
G4V39_RS00520	ENOG4107WUB	V-type ATPase 116 kDa subunit
G4V39_RS00535	ENOG4105BZU	Histidine kinase
G4V39_RS00555	ENOG4105DHT	Metal Dependent Phosphohydrolase
G4V39_RS00560	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G4V39_RS00570	ENOG4105C03	ribonuclease
G4V39_RS00580	ENOG410826D	Involved in DNA repair and RecF pathway recombination (By similarity)
G4V39_RS00590	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G4V39_RS00595	ENOG4108JA2	transcriptioN-repair coupling factor
G4V39_RS00600	ENOG4105DXN	mazG family
G4V39_RS00605	ENOG4105DFA	alanine racemase domain protein
G4V39_RS00615	ENOG4108VJ1	Transcriptional regulator (CarD family
G4V39_RS00620	ENOG4105CTP	PilT protein domain protein
G4V39_RS00625	ENOG4105C34	Pseudouridine synthase
G4V39_RS00630	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
G4V39_RS00640	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
G4V39_RS00660	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
G4V39_RS00665	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
G4V39_RS00675	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
G4V39_RS00685	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G4V39_RS00705	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G4V39_RS00715	ENOG4107S1Q	Phosphatase
G4V39_RS00730	ENOG4105D1F	ATP-binding protein
G4V39_RS00735	ENOG4107U53	septum site-determining protein minD
G4V39_RS00800	ENOG4105BZU	Histidine kinase
G4V39_RS00805	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
G4V39_RS00810	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
G4V39_RS00820	ENOG4105SWR	response regulator
G4V39_RS00840	ENOG4105D1H	recombination factor protein RarA
G4V39_RS00850	ENOG4105C8J	)-transporter
G4V39_RS00860	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
G4V39_RS00865	ENOG4105CAY	ferredoxin--nadp reductase
G4V39_RS00870	ENOG4105D0M	Protease HtpX homolog
G4V39_RS00890	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
G4V39_RS00905	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
G4V39_RS00915	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G4V39_RS00950	ENOG4105CW7	secretion protein, HlyD family
G4V39_RS00955	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
G4V39_RS00960	ENOG4105C8Q	Methyl-accepting chemotaxis
G4V39_RS00990	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
G4V39_RS01005	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
G4V39_RS01010	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
G4V39_RS01030	ENOG4105FDK	ABC transporter
G4V39_RS01035	ENOG4105FAV	ABC, transporter
G4V39_RS01040	ENOG4107YZX	Universal stress protein
G4V39_RS01050	ENOG4105EGS	Mechanosensitive ion channel
G4V39_RS01055	ENOG4108317	Binds directly to 16S ribosomal RNA (By similarity)
G4V39_RS01065	ENOG4105C8T	Leucyl-tRNA synthetase
G4V39_RS01070	ENOG4105M7K	Involved in the transcription termination process (By similarity)
G4V39_RS01080	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
G4V39_RS01085	ENOG4108R6K	riboflavin synthase, subunit alpha
G4V39_RS01090	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
G4V39_RS01105	ENOG4108JIC	nucleoside recognition domain protein
G4V39_RS01110	ENOG4105EST	Metal Dependent Phosphohydrolase
G4V39_RS01115	ENOG4105N5T	Radical SAM Protein
G4V39_RS01145	ENOG4105BZU	Histidine kinase
G4V39_RS01150	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G4V39_RS01155	ENOG4108IJF	Heavy metal efflux pump, CzcA
G4V39_RS01170	ENOG4105CQC	Prephenate dehydratase
G4V39_RS01180	ENOG4105K64	Glycosyl transferase, family 2
G4V39_RS01195	ENOG4107QZB	decarboxylase
G4V39_RS01200	ENOG4105DZS	Phenylacetate-CoA ligase
G4V39_RS01215	ENOG4105D7N	magnesium and cobalt transport protein CorA
G4V39_RS01220	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
G4V39_RS01225	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
G4V39_RS01230	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
G4V39_RS01235	ENOG4105K70	DNA-binding protein
G4V39_RS01245	ENOG4105C7K	acetolactate synthase
G4V39_RS01250	ENOG4108ZP8	Acetolactate synthase small subunit
G4V39_RS01260	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
G4V39_RS01265	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
G4V39_RS01270	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G4V39_RS01275	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G4V39_RS01280	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G4V39_RS01295	ENOG4105CP9	extracellular ligand-binding receptor
G4V39_RS01300	ENOG4105C32	Amino acid ABC transporter (Permease)
G4V39_RS01305	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
G4V39_RS01310	ENOG4105C0Z	ABC transporter
G4V39_RS01315	ENOG4108IV0	ABC, transporter
G4V39_RS01320	ENOG4105DZS	Phenylacetate-CoA ligase
G4V39_RS01340	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
G4V39_RS01350	ENOG4108RVA	ribokinase
G4V39_RS01355	ENOG4105CG5	Glycosyl transferase (Group 1
G4V39_RS01360	ENOG4107T8Q	Glycosyl transferase (Group 1
G4V39_RS01375	ENOG4105C59	p-type ATPase
G4V39_RS01380	ENOG4105DAN	ATP-dependent protease
G4V39_RS01390	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G4V39_RS01395	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
G4V39_RS01465	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
G4V39_RS01480	ENOG4105PW4	Sugar fermentation stimulation protein homolog
G4V39_RS01495	ENOG4108JIG	Anaerobic dehydrogenase
G4V39_RS01500	ENOG4108KS2	transglutaminase domain protein
G4V39_RS01505	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
G4V39_RS01510	ENOG4105D05	Receptor
G4V39_RS01530	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
G4V39_RS01535	ENOG4107RZH	Nitrite and sulphite reductase 4Fe-4S region
G4V39_RS01550	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
G4V39_RS01570	ENOG4108KXV	response regulator
G4V39_RS01590	ENOG4105C3M	thioredoxin reductase
G4V39_RS01595	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
G4V39_RS01630	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
G4V39_RS01635	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
G4V39_RS01645	ENOG4105C3R	Methionine synthase
G4V39_RS01650	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
G4V39_RS01655	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
G4V39_RS01660	ENOG4106HYN	CO dehydrogenase acetyl-CoA synthase delta subunit
G4V39_RS01690	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
G4V39_RS01695	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
G4V39_RS01700	ENOG4105CKU	formyltetrahydrofolate synthetase
G4V39_RS01705	ENOG4107KFN	Class III cytochrome C family
G4V39_RS01710	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
G4V39_RS01750	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G4V39_RS01770	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
G4V39_RS01775	ENOG4105C8U	phosphate abc transporter
G4V39_RS01780	ENOG4105E2Z	phosphate ABC transporter (Permease
G4V39_RS01785	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G4V39_RS01790	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
G4V39_RS01830	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
G4V39_RS01835	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
G4V39_RS01845	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
G4V39_RS01850	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
G4V39_RS01860	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
G4V39_RS01865	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
G4V39_RS01870	ENOG4108UJD	30S ribosomal protein S9
G4V39_RS01875	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
G4V39_RS01880	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G4V39_RS01885	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
G4V39_RS01900	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
G4V39_RS01905	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
G4V39_RS01910	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G4V39_RS01920	ENOG4105BZU	Histidine kinase
G4V39_RS01925	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
G4V39_RS01930	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
G4V39_RS01935	ENOG4105E2X	shikimate dehydrogenase
G4V39_RS01940	ENOG4105FF2	Type I DHQase
G4V39_RS01955	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
G4V39_RS01975	ENOG41090R7	Ferric uptake
G4V39_RS01990	ENOG4107QY8	reductase
G4V39_RS01995	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
G4V39_RS02000	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G4V39_RS02010	ENOG4105BZU	Histidine kinase
G4V39_RS02015	ENOG410812K	response regulator receiver protein
G4V39_RS02020	ENOG4105BZU	Histidine kinase
G4V39_RS02030	ENOG4105BZ1	(ABC) transporter
G4V39_RS02065	ENOG41082X2	rubredoxin
G4V39_RS02070	ENOG4107T8Q	Glycosyl transferase (Group 1
G4V39_RS02075	ENOG4105CAQ	asparagine synthetase
G4V39_RS02080	ENOG4108N5B	2-phosphosulfolactate phosphatase
G4V39_RS02095	ENOG4107PPM	cobalt chelatase
G4V39_RS02100	ENOG4105DVK	Precorrin-2 c20-methyltransferase
G4V39_RS02105	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
G4V39_RS02110	ENOG4105EHG	Permease protein
G4V39_RS02115	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
G4V39_RS02130	ENOG41081QV	Universal stress protein
G4V39_RS02145	ENOG4105HMI	Membrane
G4V39_RS02155	ENOG4108NVR	Methyl-accepting chemotaxis
G4V39_RS02170	ENOG4105BZU	Histidine kinase
G4V39_RS02175	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
G4V39_RS02180	ENOG4105MJ2	Competence protein
G4V39_RS02185	ENOG4108HMX	isocitrate dehydrogenase (NADP)
G4V39_RS02195	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
G4V39_RS02215	ENOG4105DA5	(ABC) transporter
G4V39_RS02220	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
G4V39_RS02225	ENOG4105E8R	UPF0173 metal-dependent hydrolase
G4V39_RS02235	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
G4V39_RS02240	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
G4V39_RS02285	ENOG4107QRT	dEAD DEAH box helicase
G4V39_RS02360	ENOG4105CFI	type iii restriction protein res subunit
G4V39_RS02395	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G4V39_RS02405	ENOG41067KJ	GYD family
G4V39_RS02415	ENOG4105CMQ	Chloride channel
G4V39_RS02425	ENOG4105CNW	domain protein
G4V39_RS02430	ENOG4105VCQ	rubredoxin
G4V39_RS02440	ENOG4105MAX	Superoxide reductase
G4V39_RS02455	ENOG4105D3R	alkyl hydroperoxide reductase
G4V39_RS02460	ENOG4108RAC	Rubrerythrin
G4V39_RS02475	ENOG4107XQ1	cobalamin (vitamin B12) biosynthesis CbiM protein
G4V39_RS02480	ENOG4108A51	
G4V39_RS02485	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
G4V39_RS02490	ENOG4108JJB	ABC transporter
G4V39_RS02500	ENOG4105FE9	pseudouridine synthase
G4V39_RS02520	ENOG4105CHJ	isochorismatase hydrolase
G4V39_RS02525	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
G4V39_RS02540	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G4V39_RS02550	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
G4V39_RS02555	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
G4V39_RS02565	ENOG4105GN4	DNA ligase
G4V39_RS02575	ENOG4105DCG	PHP domain protein
G4V39_RS02585	ENOG4105EVY	Uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent (By similarity)
G4V39_RS02610	ENOG4105E9Q	Acyl-transferase
G4V39_RS02615	ENOG4105FA2	dna polymerase iii
G4V39_RS02620	ENOG4105MA4	psp1 domain protein
G4V39_RS02625	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
G4V39_RS02630	ENOG4108Z4T	Peptidase M50
G4V39_RS02635	ENOG4105C31	Tryptophanyl-tRNA synthetase
G4V39_RS02650	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
G4V39_RS02670	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G4V39_RS02675	ENOG4105C8Q	Methyl-accepting chemotaxis
G4V39_RS02685	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
G4V39_RS02695	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
G4V39_RS02715	ENOG4108YZA	Nitrogen regulatory protein pii
G4V39_RS02720	ENOG4108YZA	Nitrogen regulatory protein pii
G4V39_RS02725	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
G4V39_RS02730	ENOG4107S73	homocitrate synthase
G4V39_RS02735	ENOG4108JUA	Transcriptional regulator
G4V39_RS02745	ENOG4108YZA	Nitrogen regulatory protein pii
G4V39_RS02760	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
G4V39_RS02765	ENOG4105CA0	peroxidase
G4V39_RS02770	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G4V39_RS02775	ENOG4105DX0	Hemolysin A
G4V39_RS02780	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
G4V39_RS02785	ENOG4105CTB	Polyprenyl synthetase
G4V39_RS02790	ENOG41084YM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G4V39_RS02795	ENOG4105DR5	peptidase
G4V39_RS02800	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G4V39_RS02810	ENOG4105BZU	Histidine kinase
G4V39_RS02815	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G4V39_RS02825	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G4V39_RS02850	ENOG4105F4P	)-transporter
G4V39_RS02855	ENOG41080XP	Cbs domain
G4V39_RS02860	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G4V39_RS02865	ENOG4105BZU	Histidine kinase
G4V39_RS02875	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
G4V39_RS02880	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
G4V39_RS02885	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
G4V39_RS02890	ENOG4105C2X	Arabinose 5-phosphate isomerase
G4V39_RS02905	ENOG4105BZS	acriflavin resistance protein
G4V39_RS02920	ENOG4107RIQ	Sulfate adenylate transferase
G4V39_RS02935	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
G4V39_RS02945	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
G4V39_RS02955	ENOG4108QV3	biosynthesis protein
G4V39_RS02990	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
G4V39_RS03005	ENOG4108ZT0	50S ribosomal protein l17
G4V39_RS03010	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G4V39_RS03015	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
G4V39_RS03020	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
G4V39_RS03025	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G4V39_RS03030	ENOG41067V7	50S ribosomal protein L36
G4V39_RS03035	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
G4V39_RS03045	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
G4V39_RS03050	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
G4V39_RS03060	ENOG4105VPB	50S ribosomal protein L30
G4V39_RS03065	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
G4V39_RS03070	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
G4V39_RS03080	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
G4V39_RS03090	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G4V39_RS03095	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
G4V39_RS03100	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
G4V39_RS03105	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
G4V39_RS03110	ENOG41082SA	50s ribosomal protein l29
G4V39_RS03115	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
G4V39_RS03120	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
G4V39_RS03125	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
G4V39_RS03130	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
G4V39_RS03135	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G4V39_RS03140	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
G4V39_RS03145	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
G4V39_RS03150	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
G4V39_RS03155	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
G4V39_RS03160	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G4V39_RS03165	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
G4V39_RS03170	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
G4V39_RS03175	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
G4V39_RS03180	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G4V39_RS03185	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G4V39_RS03190	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
G4V39_RS03195	ENOG4108VZM	50s ribosomal protein L10
G4V39_RS03205	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
G4V39_RS03210	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
G4V39_RS03215	ENOG4105PM1	preprotein translocase subunit SecE
G4V39_RS03225	ENOG4105WDJ	50S ribosomal protein L33
G4V39_RS03230	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G4V39_RS03255	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
G4V39_RS03260	ENOG4105EWK	phytoene
G4V39_RS03275	ENOG4107RIQ	Sulfate adenylate transferase
G4V39_RS03280	ENOG41084WP	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
G4V39_RS03310	ENOG4105WH1	Two component transcriptional regulator luxr family
G4V39_RS03340	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
G4V39_RS03345	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
G4V39_RS03350	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
G4V39_RS03355	ENOG4105EV6	Pfam:DUF178
G4V39_RS03360	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
G4V39_RS03365	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
G4V39_RS03370	ENOG4105DVY	radical SAM domain protein
G4V39_RS03380	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
G4V39_RS03390	ENOG4105F4G	Membrane
G4V39_RS03395	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
G4V39_RS03425	ENOG4107S21	permease
G4V39_RS03440	ENOG4105D6J	arsenicaL-resistance protein
G4V39_RS03495	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
G4V39_RS03500	ENOG4106AFQ	Histidine kinase
G4V39_RS03505	ENOG4105EYH	Exonuclease
G4V39_RS03520	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
G4V39_RS03525	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
G4V39_RS03530	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
G4V39_RS03555	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G4V39_RS03560	ENOG4105BZU	Histidine kinase
G4V39_RS03570	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
G4V39_RS03575	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
G4V39_RS03590	ENOG4105C0P	Mg chelatase subunit ChlI
G4V39_RS03595	ENOG4108UZX	fmn reductase
G4V39_RS03600	ENOG4105BZU	Histidine kinase
G4V39_RS03610	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
G4V39_RS03650	ENOG4105DUM	transcriptional regulator, lysR family
G4V39_RS03660	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
G4V39_RS03665	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
G4V39_RS03670	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G4V39_RS03675	ENOG4105VB9	50S ribosomal protein l28
G4V39_RS03690	ENOG4108TGR	phosphatase
G4V39_RS03695	ENOG4105D0M	Protease HtpX homolog
G4V39_RS03700	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G4V39_RS03705	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
G4V39_RS03715	ENOG4105C0H	protease
G4V39_RS03720	ENOG4105CKK	Glycosyl transferase, family 2
G4V39_RS03735	ENOG4107G9V	glycosyl transferase, family 39
G4V39_RS03740	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G4V39_RS03745	ENOG4105BZU	Histidine kinase
G4V39_RS03755	ENOG4105C8Q	Methyl-accepting chemotaxis
G4V39_RS03760	ENOG4105DGU	Histone deacetylase
G4V39_RS03775	ENOG4105CGK	Exodeoxyribonuclease III
G4V39_RS03780	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
G4V39_RS03790	ENOG4105CA9	Pyruvate kinase
G4V39_RS03800	ENOG4105EPH	radical SAM domain protein
G4V39_RS03820	ENOG4105CY3	ABC transporter, permease
G4V39_RS03825	ENOG41080Z8	PHOSPHOCARRIER protein
G4V39_RS03830	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G4V39_RS03840	ENOG4105CSA	Coproporphyrinogen iii oxidase
G4V39_RS03895	ENOG4105DB7	PHP domain protein
G4V39_RS03900	ENOG41081QV	Universal stress protein
G4V39_RS03920	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
G4V39_RS03935	ENOG4105DTQ	mandelate racemase muconate lactonizing
G4V39_RS03940	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
G4V39_RS03945	ENOG41082BV	acetyltransferase
G4V39_RS03955	ENOG4107QX8	SPFH domain, Band 7 family protein
G4V39_RS03965	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
G4V39_RS03970	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G4V39_RS03990	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
G4V39_RS04010	ENOG4105DQU	oxidoreductase, subunit beta
G4V39_RS04015	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
G4V39_RS04065	ENOG4108YZY	peptidylprolyl cis-trans isomerase
G4V39_RS04070	ENOG4105DIW	FeS assembly protein SUFB
G4V39_RS04075	ENOG4105C3K	feS assembly ATPase SufC
G4V39_RS04080	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
G4V39_RS04085	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
G4V39_RS04090	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
G4V39_RS04095	ENOG4105WMR	Protein CrcB homolog
G4V39_RS04100	ENOG4105DDQ	anthranilate synthase
G4V39_RS04110	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
G4V39_RS04115	ENOG4105K63	Thioredoxin
G4V39_RS04120	ENOG4105C3M	thioredoxin reductase
G4V39_RS04130	ENOG4105MRR	Transcriptional regulator (By similarity)
G4V39_RS04135	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G4V39_RS04140	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
G4V39_RS04145	ENOG4105GVR	general secretion pathway protein D
G4V39_RS04175	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
G4V39_RS04180	ENOG4105C3F	Signal peptidase i
G4V39_RS04190	ENOG4107ZTM	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
G4V39_RS04200	ENOG4107TH8	cina domain protein
G4V39_RS04210	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G4V39_RS04215	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
G4V39_RS04220	ENOG4105DFF	Rod shape-determining protein mreb
G4V39_RS04225	ENOG4105ECY	inositol monophosphatase
G4V39_RS04235	ENOG4105BZU	Histidine kinase
G4V39_RS04245	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
G4V39_RS04255	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
G4V39_RS04270	ENOG4107Z3H	Transcriptional regulator, TetR family
G4V39_RS04275	ENOG4107QNG	Phosphoribosylglycinamide synthetase
G4V39_RS04280	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G4V39_RS04285	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
G4V39_RS04295	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
G4V39_RS04300	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
G4V39_RS04305	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
G4V39_RS04320	ENOG4108RQ5	Beta-lactamase domain-containing protein
G4V39_RS04325	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G4V39_RS04330	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
G4V39_RS04335	ENOG4105D49	3-dehydroquinate synthase
G4V39_RS04340	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
G4V39_RS04350	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
G4V39_RS04355	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
G4V39_RS04360	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
G4V39_RS04365	ENOG4105C37	(CBS) domain
G4V39_RS04370	ENOG4105C37	(CBS) domain
G4V39_RS04375	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
G4V39_RS04380	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
G4V39_RS04385	ENOG4105VN1	Heat shock protein
G4V39_RS04395	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
G4V39_RS04400	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G4V39_RS04405	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
G4V39_RS04410	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
G4V39_RS04425	ENOG4107S90	membrAne
G4V39_RS04430	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
G4V39_RS04440	ENOG4105CNU	cell division protein FtsK
G4V39_RS04445	ENOG41080XS	Cobyrinic acid ac-diamide synthase
G4V39_RS04450	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
G4V39_RS04455	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
G4V39_RS04460	ENOG4105DWF	phosphomethylpyrimidine kinase
G4V39_RS04465	ENOG4108NVR	Methyl-accepting chemotaxis
G4V39_RS04475	ENOG4105DPX	Hydrogenase, large subunit
G4V39_RS04500	ENOG41071TK	Uncharacterised protein family (UPF0150)
G4V39_RS04525	ENOG41071TK	Uncharacterised protein family (UPF0150)
G4V39_RS04570	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
G4V39_RS04575	ENOG4105VEQ	Cold shock protein
G4V39_RS04585	ENOG4105DTN	riboflavin biosynthesis protein ribF
G4V39_RS04590	ENOG4105EAH	synthase
G4V39_RS04600	ENOG4105C1V	Peptidase, M16
G4V39_RS04605	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
G4V39_RS04615	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
G4V39_RS04625	ENOG41082KD	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
G4V39_RS04635	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
G4V39_RS04645	ENOG4105CHV	Transcription elongation factor NusA
G4V39_RS04650	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
G4V39_RS04660	ENOG4107QZF	nitrite reductase NADPH large subunit
G4V39_RS04675	ENOG4105K64	Glycosyl transferase, family 2
G4V39_RS04685	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
G4V39_RS04690	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
G4V39_RS04700	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
G4V39_RS04710	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
G4V39_RS04725	ENOG4105C03	ribonuclease
G4V39_RS04735	ENOG4105CHM	Aminotransferase
G4V39_RS04740	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G4V39_RS04750	ENOG4105E4C	Lytic transglycosylase catalytic
G4V39_RS04760	ENOG4105CZA	synthase
G4V39_RS04770	ENOG4105VN1	Heat shock protein
G4V39_RS04795	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
G4V39_RS04810	ENOG41066FR	extracellular solute-binding protein
G4V39_RS04815	ENOG4105D38	putrescine abc transporter
G4V39_RS04830	ENOG4105CXT	aspartate transcarbamylase
G4V39_RS04835	ENOG4105CD3	dihydroorotase
G4V39_RS04845	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
G4V39_RS04850	ENOG4105C6E	dna polymerase iii
G4V39_RS04870	ENOG4108Z6B	deaminase
G4V39_RS04885	ENOG4108V9Q	carbonic anhydrase
G4V39_RS04890	ENOG4105DR4	Methyltransferase
G4V39_RS04895	ENOG4108IQE	Amp-dependent synthetase and ligase
G4V39_RS04900	ENOG4107NFR	Fructose-1,6-bisphosphatase
G4V39_RS04905	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
G4V39_RS04910	ENOG4105EIE	fructose-bisphosphate aldolase
G4V39_RS04935	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
G4V39_RS04940	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
G4V39_RS04945	ENOG41089BK	Glutamine amido-transferase
G4V39_RS04960	ENOG4108Z0Z	intracellular protease Pfpi family
G4V39_RS04970	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
G4V39_RS04975	ENOG4108JVH	Protein of unknown function DUF43
G4V39_RS04980	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
G4V39_RS04985	ENOG4105C8Y	Acetylornithine aminotransferase
G4V39_RS04990	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
G4V39_RS05000	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
G4V39_RS05005	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
G4V39_RS05010	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
G4V39_RS05020	ENOG4105CH7	arginosuccinase
G4V39_RS05025	ENOG4105DK0	Indole-3-glycerol phosphate synthase
G4V39_RS05040	ENOG4105CHW	UPF0052 protein
G4V39_RS05055	ENOG4105BZU	Histidine kinase
G4V39_RS05075	ENOG4105CQS	hydrogenase expression formation protein HypD
G4V39_RS05090	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G4V39_RS05095	ENOG4105D22	carbon starvation protein
G4V39_RS05100	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
G4V39_RS05105	ENOG4105CZX	twitching motility protein
G4V39_RS05110	ENOG4105CZX	twitching motility protein
G4V39_RS05125	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
G4V39_RS05130	ENOG4105C25	Primosomal protein n'
G4V39_RS05140	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
G4V39_RS05145	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G4V39_RS05160	ENOG4105DPX	Hydrogenase, large subunit
G4V39_RS05165	ENOG4105E3S	small subunit
G4V39_RS05170	ENOG4108USZ	hydrogenase
G4V39_RS05180	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
G4V39_RS05215	ENOG4105D98	threonine synthase
G4V39_RS05225	ENOG4106H78	methyltransferase
G4V39_RS05230	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
G4V39_RS05235	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G4V39_RS05240	ENOG4108IYU	L-aspartate oxidase
G4V39_RS05245	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
G4V39_RS05250	ENOG4107SVH	Potassium channel protein
G4V39_RS05260	ENOG4105W5Q	DNA repair protein (RadC
G4V39_RS05265	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
G4V39_RS05270	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
G4V39_RS05280	ENOG4107QI6	Cysteine desulfurase
G4V39_RS05285	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
G4V39_RS05300	ENOG4105EPH	radical SAM domain protein
G4V39_RS05310	ENOG4105CRE	cytochrome C
G4V39_RS05325	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G4V39_RS05345	ENOG4105C8Q	Methyl-accepting chemotaxis
G4V39_RS05360	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
G4V39_RS05365	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
G4V39_RS05370	ENOG4105BZU	Histidine kinase
G4V39_RS05405	ENOG4105NTZ	Preprotein translocase subunit SecG
G4V39_RS05410	ENOG4105CP7	Triose-phosphate isomerase
G4V39_RS05415	ENOG4105BZA	Phosphoglycerate kinase
G4V39_RS05420	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G4V39_RS05455	ENOG4105BZU	Histidine kinase
G4V39_RS05465	ENOG4105BZU	Histidine kinase
G4V39_RS05470	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
G4V39_RS05475	ENOG4108V3W	Chemotaxis protein, CheW
G4V39_RS05480	ENOG4105C8Q	Methyl-accepting chemotaxis
G4V39_RS05490	ENOG4107QJE	Chromosome Partitioning Protein
G4V39_RS05500	ENOG4105DSE	periplasmic solute binding protein
G4V39_RS05515	ENOG4105BZU	Histidine kinase
G4V39_RS05520	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
G4V39_RS05525	ENOG4108YZA	Nitrogen regulatory protein pii
G4V39_RS05530	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
G4V39_RS05540	ENOG4105DJZ	UPF0182 protein
G4V39_RS05545	ENOG4105CUB	amino acid
G4V39_RS05605	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
G4V39_RS05610	ENOG4105D48	metallophosphoesterase
G4V39_RS05615	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
G4V39_RS05635	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
G4V39_RS05640	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G4V39_RS05645	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
G4V39_RS05650	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
G4V39_RS05655	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
G4V39_RS05660	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G4V39_RS05665	ENOG410835G	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
G4V39_RS05675	ENOG4105CNI	cell division protein FtsW
G4V39_RS05680	ENOG4105CJN	penicillin-binding protein
G4V39_RS05700	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
G4V39_RS05705	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
G4V39_RS05720	ENOG41088YS	Glycosyl transferase (Group 1
G4V39_RS05725	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
G4V39_RS05740	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
G4V39_RS05750	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G4V39_RS05755	ENOG41079HR	Phosphate-Selective Porin O and P
G4V39_RS05765	ENOG4105NBF	ammecr1 domain protein
G4V39_RS05775	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
G4V39_RS05780	ENOG4105FB2	class II Aldolase
G4V39_RS05795	ENOG4105D7Q	type ii secretion system
G4V39_RS05820	ENOG4105CMM	transposase
G4V39_RS05830	ENOG4105D5G	Transposase
G4V39_RS05840	ENOG4105D7W	serine acetyltransferase
G4V39_RS05850	ENOG4105DWV	Homoserine O-trans-acetylase
G4V39_RS05860	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
G4V39_RS05865	ENOG4105C8Q	Methyl-accepting chemotaxis
G4V39_RS05870	ENOG4108V3W	Chemotaxis protein, CheW
G4V39_RS05880	ENOG4105BZU	Histidine kinase
G4V39_RS05885	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
G4V39_RS05890	ENOG4108VYJ	response regulator receiver protein
G4V39_RS05895	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
G4V39_RS05900	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
G4V39_RS05905	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
G4V39_RS05910	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
G4V39_RS05920	ENOG4105C5R	Aminotransferase
G4V39_RS05925	ENOG4105DGU	Histone deacetylase
G4V39_RS05930	ENOG4105CD5	CoA-binding domain protein
G4V39_RS05945	ENOG4105CHM	Aminotransferase
G4V39_RS05955	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G4V39_RS05960	ENOG4105ES5	Histidine kinase
G4V39_RS05975	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
G4V39_RS05985	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G4V39_RS05990	ENOG4105CFH	Aspartokinase
G4V39_RS05995	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G4V39_RS06000	ENOG4105M6F	mutator MutT protein
G4V39_RS06015	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
G4V39_RS06030	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
G4V39_RS06035	ENOG4105VH4	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G4V39_RS06040	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
G4V39_RS06045	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G4V39_RS06050	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
G4V39_RS06060	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
G4V39_RS06065	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
G4V39_RS06070	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
G4V39_RS06080	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
G4V39_RS06090	ENOG4105CJ1	ABC, transporter
G4V39_RS06095	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G4V39_RS06125	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
G4V39_RS06130	ENOG4108UNF	response regulator
G4V39_RS06135	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
G4V39_RS06140	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
G4V39_RS06145	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G4V39_RS06155	ENOG4105C8Q	Methyl-accepting chemotaxis
G4V39_RS06160	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
G4V39_RS06165	ENOG4105C8Q	Methyl-accepting chemotaxis
G4V39_RS06170	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G4V39_RS06185	ENOG4105D52	delta-aminolevulinic acid dehydratase
G4V39_RS06205	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
G4V39_RS06220	ENOG4105C01	Dihydroxy-acid dehydratase
G4V39_RS06250	ENOG4105K4H	Nlp p60 protein
G4V39_RS06255	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
G4V39_RS06270	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
G4V39_RS06275	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
G4V39_RS06280	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
G4V39_RS06290	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G4V39_RS06300	ENOG4108I0Q	anthranilate phosphoribosyltransferase
G4V39_RS06310	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
G4V39_RS06320	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
G4V39_RS06325	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
G4V39_RS06330	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
G4V39_RS06335	ENOG4105CH7	arginosuccinase
G4V39_RS06345	ENOG4105C75	arginyL-tRNA synthetase
G4V39_RS06355	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
G4V39_RS06370	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
G4V39_RS06385	ENOG4105CUY	Mechanosensitive ion channel
G4V39_RS06390	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
G4V39_RS06395	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G4V39_RS06405	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
G4V39_RS06410	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
G4V39_RS06420	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
G4V39_RS06430	ENOG4105D00	flagellar biosynthetic protein flhB
G4V39_RS06455	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G4V39_RS06460	ENOG4107QI6	Cysteine desulfurase
G4V39_RS06465	ENOG4105K6T	rare lipoprotein A
G4V39_RS06470	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
G4V39_RS06475	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G4V39_RS06500	ENOG4105FA0	parb-like partition protein
G4V39_RS06525	ENOG4105KJJ	Uncharacterized ACR, COG1993
G4V39_RS06535	ENOG4107GFK	fumarate
G4V39_RS06545	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
G4V39_RS06550	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
G4V39_RS06565	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
G4V39_RS06575	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G4V39_RS06585	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G4V39_RS06590	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
G4V39_RS06600	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G4V39_RS06610	ENOG4105BZU	Histidine kinase
G4V39_RS06615	ENOG4108RE9	Phosphodiesterase
G4V39_RS06625	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
G4V39_RS06640	ENOG4105DC1	bifunctional purine biosynthesis protein purh
G4V39_RS06680	ENOG4105PXI	polysaccharide deacetylase
G4V39_RS06685	ENOG4105CN1	protease
G4V39_RS06700	ENOG4105CAK	Cell division ATP-binding protein ftsE
G4V39_RS06705	ENOG4105KHS	type IV fimbrial pilin protein
G4V39_RS06710	ENOG4105X0D	Fimbrial protein
G4V39_RS06715	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
G4V39_RS06720	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
G4V39_RS06730	ENOG4105DSJ	YicC domain protein
G4V39_RS06735	ENOG4105KC4	UPF0296 protein
G4V39_RS06740	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
G4V39_RS06745	ENOG4105C2N	RNA methyltransferase TrmH family group 3
G4V39_RS06750	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
G4V39_RS06755	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
G4V39_RS06765	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
G4V39_RS06770	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
G4V39_RS06785	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G4V39_RS06795	ENOG4105EGD	dinuclear metal center protein, YbgI family
G4V39_RS06805	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G4V39_RS06810	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
G4V39_RS06815	ENOG4105C98	muts2 protein
G4V39_RS06820	ENOG41084JP	30S ribosomal protein S21
G4V39_RS06830	ENOG4105E3H	phosphoglycerate mutase
G4V39_RS06840	ENOG4105CB5	ATP-dependent DNA helicase recG
G4V39_RS06850	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
G4V39_RS06865	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
G4V39_RS06875	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G4V39_RS06880	ENOG4105CDH	Citrulline--aspartate ligase
G4V39_RS06885	ENOG4105DBV	ornithine carbamoyltransferase
G4V39_RS06890	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
G4V39_RS06895	ENOG4105CP9	extracellular ligand-binding receptor
G4V39_RS06910	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
G4V39_RS06915	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
G4V39_RS06925	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
G4V39_RS06930	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
G4V39_RS06935	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
G4V39_RS06945	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
G4V39_RS06960	ENOG4105ER2	Ompa motb domain protein
G4V39_RS06965	ENOG4105E14	MotA TolQ exbB proton channel
G4V39_RS06970	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
G4V39_RS06975	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
G4V39_RS06980	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
G4V39_RS06985	ENOG4105CDU	Replicative dna helicase
G4V39_RS06990	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
G4V39_RS07005	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
G4V39_RS07010	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
G4V39_RS07030	ENOG4105C0H	protease
G4V39_RS07035	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G4V39_RS07045	ENOG4105CPI	Metal Dependent Phosphohydrolase
G4V39_RS07050	ENOG4105CHC	glucokinase (EC 2.7.1.2)
G4V39_RS07060	ENOG4105KCK	Peptidoglycan-associated lipoprotein
G4V39_RS07065	ENOG4105WMT	general secretion pathway protein h
G4V39_RS07100	ENOG4105E3H	phosphoglycerate mutase
G4V39_RS07110	ENOG4105C7Z	Conserved Protein
G4V39_RS07120	ENOG4105C8N	cysteinyl-tRNA synthetase
G4V39_RS07125	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
G4V39_RS07130	ENOG4107QY8	reductase
G4V39_RS07135	ENOG4108NEM	leader-binding protein dmsD
G4V39_RS07145	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
G4V39_RS07155	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
G4V39_RS07160	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
G4V39_RS07180	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
G4V39_RS07185	ENOG4105VF7	tolerance protein
G4V39_RS07190	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
G4V39_RS07195	ENOG4105EHZ	conserved protein UCP016719
G4V39_RS07205	ENOG4105EGS	Mechanosensitive ion channel
G4V39_RS07215	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
G4V39_RS07225	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
G4V39_RS07235	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
G4V39_RS07240	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
G4V39_RS07245	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
G4V39_RS07250	ENOG4105DZ1	carboxypeptidase
G4V39_RS07255	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
G4V39_RS07270	ENOG4105CVE	Lytic murein transglycosylase
G4V39_RS07275	ENOG4105DR5	peptidase
G4V39_RS07305	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
G4V39_RS07320	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
G4V39_RS07335	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G4V39_RS07350	ENOG4105KNI	merR family transcriptional Regulator
G4V39_RS07355	ENOG4108M19	cytochrome C
G4V39_RS07390	ENOG41084BP	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
G4V39_RS07395	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G4V39_RS07400	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G4V39_RS07420	ENOG4105BZU	Histidine kinase
G4V39_RS07425	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
G4V39_RS07450	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
G4V39_RS07460	ENOG4108UM1	dedA family
G4V39_RS07465	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
G4V39_RS07480	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
G4V39_RS07485	ENOG4108JQC	penicillin-binding protein 1A
G4V39_RS07490	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
G4V39_RS07505	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
G4V39_RS07525	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G4V39_RS07530	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
G4V39_RS07540	ENOG4105K63	Thioredoxin
G4V39_RS07560	ENOG41061AI	Protein of unknown function (DUF2905)
G4V39_RS07565	ENOG4105WPN	DNA integration recombination invertion protein
G4V39_RS07570	ENOG4105EB3	Histidine kinase
G4V39_RS07595	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
G4V39_RS07645	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
G4V39_RS07655	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
G4V39_RS07660	ENOG4108JU5	Magnesium and cobalt efflux protein
G4V39_RS07670	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G4V39_RS07675	ENOG4105C0H	protease
G4V39_RS07680	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
G4V39_RS07695	ENOG4107SDT	Homocitrate synthase
G4V39_RS07700	ENOG4105C9M	aspartyl-trna synthetase
G4V39_RS07715	ENOG4107QHF	type ii secretion system protein e
G4V39_RS07725	ENOG4105CXV	gliding motility protein
G4V39_RS07735	ENOG4105D58	Diguanylate phosphodiesterase
G4V39_RS07745	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
G4V39_RS07750	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
G4V39_RS07755	ENOG4105Z0W	Dissimilatory sulfite reductase D
G4V39_RS07785	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G4V39_RS07810	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
G4V39_RS07820	ENOG4108UVJ	appr-1-p processing domain protein
G4V39_RS07830	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
G4V39_RS07835	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
G4V39_RS07840	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
G4V39_RS07845	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
G4V39_RS07850	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
G4V39_RS07855	ENOG41084M4	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
G4V39_RS07860	ENOG4105VG0	50S ribosomal protein l34
G4V39_RS07865	ENOG4105KNH	Nucleic acid-binding protein
G4V39_RS07870	ENOG41084CW	50S ribosomal protein L32
G4V39_RS07880	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
G4V39_RS07890	ENOG4105BZJ	Electron transfer flavoprotein
G4V39_RS07900	ENOG4105CHR	reductase
G4V39_RS07905	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
G4V39_RS07910	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G4V39_RS07915	ENOG4108YZG	isomerase
G4V39_RS07920	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
G4V39_RS07925	ENOG4108UK2	deaminase
G4V39_RS07930	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
G4V39_RS07945	ENOG4105CE1	Ferrous iron transport protein b
G4V39_RS07975	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
G4V39_RS07995	ENOG4108JUB	Transcriptional regulator
G4V39_RS08000	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
G4V39_RS08015	ENOG4105KNI	merR family transcriptional Regulator
G4V39_RS08025	ENOG41072GX	Peptidase M22 Glycoprotease
G4V39_RS08030	ENOG4105DZP	Membrane-associated zinc metalloprotease
G4V39_RS08035	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
G4V39_RS08055	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
G4V39_RS08060	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
G4V39_RS08065	ENOG4105CE9	30S ribosomal protein S2
G4V39_RS08070	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
G4V39_RS08080	ENOG4105CTQ	phosphohexokinase
G4V39_RS08090	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
G4V39_RS08100	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G4V39_RS08120	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
G4V39_RS08125	ENOG4105VZ9	UPF0235 protein
G4V39_RS08130	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
G4V39_RS08135	ENOG4108VIA	integral membrane protein
G4V39_RS08140	ENOG4105CEV	competence damage-inducible protein
G4V39_RS08150	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
G4V39_RS08175	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
G4V39_RS08195	ENOG4107YU2	histidine triad (hIT) protein
G4V39_RS08200	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G4V39_RS08230	ENOG4105C8Q	Methyl-accepting chemotaxis
G4V39_RS08235	ENOG4105CV1	Transketolase (EC 2.2.1.1)
G4V39_RS08240	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
G4V39_RS08245	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
G4V39_RS08260	ENOG4108IUZ	ABC transporter
G4V39_RS08265	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G4V39_RS08275	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
G4V39_RS08290	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
G4V39_RS08295	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
G4V39_RS08325	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
G4V39_RS08335	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
G4V39_RS08340	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
G4V39_RS08345	ENOG4105CRE	cytochrome C
G4V39_RS08350	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
G4V39_RS08360	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
G4V39_RS08375	ENOG4105EJ5	oxidoreductase gamma subunit
G4V39_RS08385	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
G4V39_RS08390	ENOG4105DDK	oxidoreductase, beta subunit
G4V39_RS08400	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
G4V39_RS08405	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
G4V39_RS08440	ENOG41080X4	futalosine nucleosidase
G4V39_RS08445	ENOG4105E63	Pfam:DUF178
G4V39_RS08450	ENOG4105E02	MotA TolQ exbB proton channel
G4V39_RS08455	ENOG4105SG9	biopolymer transport protein, ExbD
G4V39_RS08465	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
G4V39_RS08480	ENOG4105C8N	cysteinyl-tRNA synthetase
G4V39_RS08490	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
G4V39_RS08495	ENOG41068KF	Universal stress protein
G4V39_RS08500	ENOG4107TSN	permease
G4V39_RS08515	ENOG4105BZU	Histidine kinase
G4V39_RS08545	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
G4V39_RS08565	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
G4V39_RS08575	ENOG4107QKV	phosphomannomutase
G4V39_RS08580	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
G4V39_RS08615	ENOG4107TSN	permease
G4V39_RS08625	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
G4V39_RS08630	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G4V39_RS08635	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G4V39_RS08640	ENOG4105BZU	Histidine kinase
G4V39_RS08650	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
G4V39_RS08660	ENOG4105CAS	nag kinase
G4V39_RS08670	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
G4V39_RS08675	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G4V39_RS08685	ENOG4107YIW	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
G4V39_RS08690	ENOG4105WH1	Two component transcriptional regulator luxr family
G4V39_RS08710	ENOG4105CZN	Potassium uptake protein
G4V39_RS08715	ENOG4107ZYR	domain protein
G4V39_RS08725	ENOG4105D2T	synthase
G4V39_RS08735	ENOG4105C26	Dehydrogenase
G4V39_RS08740	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
G4V39_RS08745	ENOG4105F0R	Cytidylyltransferase
G4V39_RS08770	ENOG4105EY8	ABC transporter
G4V39_RS08785	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
G4V39_RS08795	ENOG4108TJN	glycosyl transferase group 1
G4V39_RS08800	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
G4V39_RS08805	ENOG4105CPK	Glycosyl transferase (Group 1
G4V39_RS08810	ENOG4105D3Q	Sugar transferase
G4V39_RS08830	ENOG4105CRK	lysyL-tRNA synthetase
G4V39_RS08840	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G4V39_RS08845	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G4V39_RS08850	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G4V39_RS08855	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
G4V39_RS08860	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G4V39_RS08865	ENOG4105GYT	Protein of unknown function (DUF1009)
G4V39_RS08870	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
G4V39_RS08875	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G4V39_RS08880	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
G4V39_RS08885	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
G4V39_RS08895	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
G4V39_RS08900	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
G4V39_RS08905	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
G4V39_RS08910	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
G4V39_RS08925	ENOG4107QY8	reductase
G4V39_RS08930	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
G4V39_RS08935	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G4V39_RS08940	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G4V39_RS08945	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G4V39_RS08950	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G4V39_RS08955	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
G4V39_RS08960	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G4V39_RS08965	ENOG4105DF2	NADH dehydrogenase subunit j
G4V39_RS08970	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G4V39_RS08980	ENOG4105C8S	subunit m
G4V39_RS09000	ENOG4105BZU	Histidine kinase
G4V39_RS09005	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G4V39_RS09010	ENOG4105CAQ	asparagine synthetase
G4V39_RS09020	ENOG4108RC0	Electron transport protein
G4V39_RS09025	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
G4V39_RS09030	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
G4V39_RS09050	ENOG4105CHM	Aminotransferase
G4V39_RS09065	ENOG4108UUM	single-stranded DNA-binding protein
G4V39_RS09075	ENOG4108P62	biosynthesis protein (CbiG)
G4V39_RS09080	ENOG4105E4R	Precorrin-3B C17-methyltransferase
G4V39_RS09090	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
G4V39_RS09095	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G4V39_RS09100	ENOG4105CFG	Acts as a chaperone (By similarity)
G4V39_RS09105	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G4V39_RS09110	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
G4V39_RS09120	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G4V39_RS09125	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
G4V39_RS09140	ENOG4105VJV	50s ribosomal protein L35
G4V39_RS09145	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
G4V39_RS09150	ENOG4105C22	threonyL-tRNA synthetase
G4V39_RS09160	ENOG4105D64	Mechanosensitive ion channel
G4V39_RS09185	ENOG4108WTY	tRNA (Guanine-N(1)-)-methyltransferase
G4V39_RS09190	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
G4V39_RS09195	ENOG41082N4	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
G4V39_RS09200	ENOG4105VB6	UPF0109 protein
G4V39_RS09205	ENOG4105K5M	30s ribosomal protein S16
G4V39_RS09215	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
G4V39_RS09230	ENOG41082RQ	UPF0102 protein
G4V39_RS09235	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G4V39_RS09240	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
G4V39_RS09245	ENOG4105CPF	Cell wall formation (By similarity)
G4V39_RS09260	ENOG4105CQB	FAD linked oxidase domain protein
G4V39_RS09270	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
G4V39_RS09280	ENOG4105BZU	Histidine kinase
G4V39_RS09305	ENOG4105CUC	YeeE YedE family protein
G4V39_RS09310	ENOG4105VFE	sira family
G4V39_RS09340	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
G4V39_RS09345	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
G4V39_RS09350	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
G4V39_RS09355	ENOG41082DI	50s ribosomal protein l31
G4V39_RS09370	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G4V39_RS09375	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
G4V39_RS09390	ENOG41081FY	multiple antibiotic resistance (MarC)-related
G4V39_RS09395	ENOG4107Y9E	nuclease
G4V39_RS09400	ENOG4105F6S	Spore photoproduct lyase
G4V39_RS09410	ENOG4105C8V	SAICAR synthetase
G4V39_RS09425	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
G4V39_RS09450	ENOG4107S2Z	UPF0761 membrane protein
G4V39_RS09455	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
G4V39_RS09460	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
G4V39_RS09465	ENOG4108094	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
G4V39_RS09470	ENOG4108HU6	Metal dependent phosphohydrolase
G4V39_RS09485	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
G4V39_RS09490	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
G4V39_RS09495	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
G4V39_RS09520	ENOG4105CJR	Integral membrane protein (MviN
G4V39_RS09535	ENOG4105EM7	Selenocysteine-specific translation elongation factor
G4V39_RS09540	ENOG4105HHA	aminodeoxychorismate lyase
G4V39_RS09545	ENOG4108V6E	Cell division protein mraZ
G4V39_RS09550	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
G4V39_RS09560	ENOG4105CJN	penicillin-binding protein
G4V39_RS09570	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
G4V39_RS09575	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
G4V39_RS09580	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
G4V39_RS09585	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
G4V39_RS09590	ENOG4105DFU	Cell wall formation (By similarity)
G4V39_RS09595	ENOG4105D4A	Cell wall formation (By similarity)
G4V39_RS09600	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
G4V39_RS09605	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
G4V39_RS09610	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
G4V39_RS09630	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
G4V39_RS09640	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
G4V39_RS09650	ENOG4105BZU	Histidine kinase
G4V39_RS09665	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
G4V39_RS09670	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
G4V39_RS09680	ENOG4107RFW	hydrolase family 57
G4V39_RS09685	ENOG4105C5X	domain protein
G4V39_RS09695	ENOG4105BZU	Histidine kinase
G4V39_RS09700	ENOG41062D9	Histidine kinase
G4V39_RS09710	ENOG4105D05	Receptor
G4V39_RS09715	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
G4V39_RS09720	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
G4V39_RS09725	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
G4V39_RS09730	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
G4V39_RS09740	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
G4V39_RS09745	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
G4V39_RS09750	ENOG4105K46	50S ribosomal protein l27
G4V39_RS09760	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G4V39_RS09765	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
G4V39_RS09820	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
G4V39_RS09870	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
G4V39_RS09875	ENOG4105C0Z	ABC transporter
G4V39_RS09880	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
G4V39_RS09885	ENOG4105C32	Amino acid ABC transporter (Permease)
G4V39_RS09915	ENOG4105CMI	transporter
G4V39_RS09920	ENOG4105CJ1	ABC, transporter
G4V39_RS09925	ENOG4105CJ1	ABC, transporter
G4V39_RS09940	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
G4V39_RS09945	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
G4V39_RS09980	ENOG4105CUZ	uba thif-type nad fad binding protein
G4V39_RS10005	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
G4V39_RS10020	ENOG4105CPK	Glycosyl transferase (Group 1
G4V39_RS10025	ENOG4105CAQ	asparagine synthetase
G4V39_RS10030	ENOG4108KMV	Glycosyl transferase (Group 1
G4V39_RS10035	ENOG4107EF8	Glycosyl transferase (Group 1
G4V39_RS10040	ENOG4105CMR	udp-glucose 4-epimerase
G4V39_RS10075	ENOG4105CPK	Glycosyl transferase (Group 1
G4V39_RS10090	ENOG4105CMM	transposase
G4V39_RS10140	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
G4V39_RS10145	ENOG4105CAQ	asparagine synthetase
G4V39_RS10160	ENOG4105DFM	M18 family aminopeptidase
G4V39_RS10180	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
G4V39_RS10185	ENOG4105C8Q	Methyl-accepting chemotaxis
G4V39_RS10205	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
G4V39_RS10210	ENOG4108NVR	Methyl-accepting chemotaxis
G4V39_RS10215	ENOG4105C3G	gtp-binding protein
G4V39_RS10225	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
G4V39_RS10230	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
G4V39_RS10260	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G4V39_RS10270	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G4V39_RS10275	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
G4V39_RS10280	ENOG4108ZC9	flagellar basal-body rod protein flgc
G4V39_RS10285	ENOG41084DA	flagellar hook-basal body complex protein fliE
G4V39_RS10290	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
G4V39_RS10295	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G4V39_RS10300	ENOG4105W2B	Flagellar assembly protein
G4V39_RS10325	ENOG410822I	Flagellar hook capping protein
G4V39_RS10330	ENOG4105BZE	flagellar hook protein, FlgE
G4V39_RS10335	ENOG4105BZE	flagellar hook protein, FlgE
G4V39_RS10340	ENOG4105X6C	Flagellar basal body-associated protein FliL
G4V39_RS10345	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G4V39_RS10350	ENOG4105DD5	Flagellar motor switch protein
G4V39_RS10360	ENOG4105CN7	Flagellar biosynthetic protein FliP
G4V39_RS10365	ENOG4105VS8	Flagellar biosynthetic protein fliq
G4V39_RS10370	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
G4V39_RS10375	ENOG4105D00	flagellar biosynthetic protein flhB
G4V39_RS10380	ENOG4105D7B	Flagellar biosynthesis protein flha
G4V39_RS10385	ENOG4105FZW	flagellar biosynthesis regulator FlhF
G4V39_RS10395	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G4V39_RS10400	ENOG4108VYJ	response regulator receiver protein
G4V39_RS10420	ENOG4105CGA	flagellar basal-body rod protein FlgG
G4V39_RS10425	ENOG4105CGA	flagellar basal-body rod protein FlgG
G4V39_RS10435	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
G4V39_RS10440	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
G4V39_RS10445	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
G4V39_RS10460	ENOG4105DTJ	flagellar hook-associated protein
G4V39_RS10470	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
G4V39_RS10485	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
G4V39_RS10490	ENOG4105EI2	Pseudouridine synthase
G4V39_RS10500	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
G4V39_RS10505	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
G4V39_RS10525	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
G4V39_RS10535	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
G4V39_RS10540	ENOG4108UMR	transcriptional regulator AsnC family
G4V39_RS10560	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
G4V39_RS10565	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
G4V39_RS10585	ENOG4105BZU	Histidine kinase
G4V39_RS10605	ENOG4109015	Biopolymer transport protein exbD tolR
G4V39_RS10615	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
G4V39_RS10620	ENOG4105C3R	Methionine synthase
G4V39_RS10625	ENOG4107QK7	reductase
G4V39_RS10630	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
G4V39_RS10640	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
G4V39_RS10655	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
G4V39_RS10670	ENOG4105HEE	Binding Domain protein
G4V39_RS10675	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G4V39_RS10680	ENOG4105BZU	Histidine kinase
G4V39_RS10685	ENOG410690C	hydroxylamine oxidase
G4V39_RS10705	ENOG4107TE5	Lipid kinase
G4V39_RS10710	ENOG4105KNE	Phosphatidate cytidylyltransferase
G4V39_RS10725	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
G4V39_RS10735	ENOG4108JQ7	(ABC) transporter
G4V39_RS10740	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
G4V39_RS10835	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
G4V39_RS10840	ENOG4105C9X	ppx gppa phosphatase
G4V39_RS10850	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
G4V39_RS10855	ENOG4105CAT	Cytidine monophosphate kinase
G4V39_RS10860	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G4V39_RS10865	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
G4V39_RS10880	ENOG4107U32	Beta-lactamase domain protein
G4V39_RS10890	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
G4V39_RS10895	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
G4V39_RS10900	ENOG4105C4M	(Ubiquinol oxidase) subunit I
G4V39_RS10910	ENOG4105BZU	Histidine kinase
G4V39_RS10950	ENOG4108RCM	Nitroreductase
G4V39_RS10960	ENOG4105D16	lipopolysaccharide heptosyltransferase i
G4V39_RS10965	ENOG4105CPK	Glycosyl transferase (Group 1
G4V39_RS10970	ENOG4105CPK	Glycosyl transferase (Group 1
G4V39_RS10980	ENOG4107BJW	polysaccharide deacetylase
G4V39_RS10985	ENOG4107XU6	Glycosyl transferase (Group 1
G4V39_RS10990	ENOG4105GXZ	Ferredoxin-type protein NapH
G4V39_RS11010	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
G4V39_RS11020	ENOG4105EYU	Glutamine amido-transferase
G4V39_RS11040	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
G4V39_RS11055	ENOG410620I	Diguanylate cyclase
G4V39_RS11060	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
G4V39_RS11065	ENOG4105VTS	DnaJ-like, subfamily C
G4V39_RS11075	ENOG4105CNW	domain protein
G4V39_RS11100	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
G4V39_RS11105	ENOG4105C2M	dna polymerase I
G4V39_RS11110	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
G4V39_RS11120	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
G4V39_RS11125	ENOG4105C0B	DNA polymerase III (alpha subunit)
G4V39_RS11130	ENOG4105G5W	regulator Fur family
G4V39_RS11170	ENOG4105CTK	cobaltochelatase, cobn subunit
G4V39_RS11190	ENOG4108JJB	ABC transporter