locus-tag	class	description
CDC40_RS00010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDC40_RS00025	COG0804	urea catabolic process
CDC40_RS00040	COG4956	integral membrane protein (PIN domain superfamily)
CDC40_RS00065	COG1473	amidohydrolase
CDC40_RS00070	COG2954	triphosphatase activity
CDC40_RS00075	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
CDC40_RS00080	COG2211	Major facilitator Superfamily
CDC40_RS00095	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CDC40_RS00105	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CDC40_RS00145	COG2205	protein histidine kinase activity
CDC40_RS00165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDC40_RS00170	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CDC40_RS00185	COG0457	Tetratricopeptide repeat
CDC40_RS00185	COG0463	Glycosyl transferase, family 2
CDC40_RS00195	COG0811	peptide transport
CDC40_RS00200	COG1595	DNA-templated transcription, initiation
CDC40_RS00225	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDC40_RS00230	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CDC40_RS00240	COG0484	heat shock protein binding
CDC40_RS00245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CDC40_RS00250	COG2264	protein methyltransferase activity
CDC40_RS00255	COG0438	transferase activity, transferring glycosyl groups
CDC40_RS00270	COG0832	Belongs to the urease beta subunit family
CDC40_RS00275	COG0259	pyridoxamine-phosphate oxidase activity
CDC40_RS00285	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CDC40_RS00290	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CDC40_RS00305	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CDC40_RS00315	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDC40_RS00325	COG0429	hydrolase of the alpha beta-hydrolase fold
CDC40_RS00340	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CDC40_RS00365	COG0840	transmembrane signaling receptor activity
CDC40_RS00370	COG0784	Response regulator, receiver
CDC40_RS00370	COG2198	Histidine kinase
CDC40_RS00370	COG0643	Histidine kinase
CDC40_RS00375	COG4581	dead DEAH box helicase
CDC40_RS00410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDC40_RS00430	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CDC40_RS00465	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDC40_RS00470	COG0484	heat shock protein binding
CDC40_RS00475	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CDC40_RS00485	COG0460	homoserine dehydrogenase
CDC40_RS00490	COG4208	sulfate ABC transporter
CDC40_RS00495	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CDC40_RS00500	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CDC40_RS00510	COG1429	ligase activity, forming nitrogen-metal bonds
CDC40_RS00515	COG1122	ATPase activity
CDC40_RS00525	COG0861	Integral membrane protein TerC family
CDC40_RS00530	COG0105	UTP biosynthetic process
CDC40_RS00535	COG0384	phenazine biosynthesis protein PhzF
CDC40_RS00545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDC40_RS00550	COG2268	Band 7 protein
CDC40_RS00555	COG2268	Band 7 protein
CDC40_RS00565	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CDC40_RS00565	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CDC40_RS00580	COG1473	amidohydrolase
CDC40_RS00595	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CDC40_RS00605	COG1799	cell septum assembly
CDC40_RS00610	COG0310	cobalt ion transport
CDC40_RS00615	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
CDC40_RS00625	COG1122	ATPase activity
CDC40_RS00640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDC40_RS00645	COG0287	Prephenate dehydrogenase
CDC40_RS00660	COG0515	serine threonine protein kinase
CDC40_RS00670	COG0515	serine threonine protein kinase
CDC40_RS00670	COG1357	PFAM Pentapeptide repeats (8 copies)
CDC40_RS00690	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CDC40_RS00710	COG1252	NADH dehydrogenase
CDC40_RS00715	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CDC40_RS00740	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CDC40_RS00750	COG0668	transmembrane transport
CDC40_RS00755	COG2081	HI0933 family
CDC40_RS00760	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CDC40_RS00765	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CDC40_RS00775	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CDC40_RS00780	COG0745	RESPONSE REGULATOR receiver
CDC40_RS00790	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CDC40_RS00800	COG0596	Alpha beta hydrolase
CDC40_RS00805	COG3706	GGDEF domain
CDC40_RS00810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CDC40_RS00820	COG1716	ATPase activity
CDC40_RS00825	COG0515	serine threonine protein kinase
CDC40_RS00905	COG1131	(ABC) transporter
CDC40_RS00915	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDC40_RS00915	COG0512	Glutamine amidotransferase of anthranilate synthase
CDC40_RS00940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDC40_RS00960	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDC40_RS00970	COG3266	domain, Protein
CDC40_RS00970	COG0515	serine threonine protein kinase
CDC40_RS00990	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CDC40_RS01005	COG0450	alkyl hydroperoxide reductase
CDC40_RS01020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDC40_RS01035	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CDC40_RS01050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CDC40_RS01060	COG0724	RNA recognition motif
CDC40_RS01075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CDC40_RS01075	COG0678	peroxiredoxin activity
CDC40_RS01100	COG3118	belongs to the thioredoxin family
CDC40_RS01110	COG0747	negative chemotaxis
CDC40_RS01115	COG3956	TIGRFAM MazG family protein
CDC40_RS01120	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CDC40_RS01145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDC40_RS01160	COG0514	ATP-dependent DNA helicase (RecQ)
CDC40_RS01195	COG1666	GTP binding
CDC40_RS01205	COG0443	Heat shock 70 kDa protein
CDC40_RS01210	COG0484	heat shock protein binding
CDC40_RS01225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDC40_RS01240	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CDC40_RS01245	COG2223	nitrite transmembrane transporter activity
CDC40_RS01250	COG0058	SHG alpha-glucan phosphorylase activity
CDC40_RS01260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CDC40_RS01275	COG0442	prolyl-tRNA aminoacylation
CDC40_RS01290	COG0697	spore germination
CDC40_RS01295	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CDC40_RS01310	COG0504	CTP synthase activity
CDC40_RS01320	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CDC40_RS01330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDC40_RS01330	COG0574	Belongs to the PEP-utilizing enzyme family
CDC40_RS01335	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDC40_RS01340	COG0297	glycogen (starch) synthase activity
CDC40_RS01350	COG1420	regulation of RNA biosynthetic process
CDC40_RS01355	COG0505	Belongs to the CarA family
CDC40_RS01360	COG1175	transmembrane transport
CDC40_RS01365	COG0484	heat shock protein binding
CDC40_RS01395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDC40_RS01440	COG0436	Aminotransferase
CDC40_RS01445	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CDC40_RS01450	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CDC40_RS01465	COG2203	Gaf domain
CDC40_RS01465	COG3706	GGDEF domain
CDC40_RS01465	COG4251	negative regulation of phosphorylation
CDC40_RS01465	COG5001	Diguanylate cyclase
CDC40_RS01470	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CDC40_RS01475	COG2205	protein histidine kinase activity
CDC40_RS01495	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDC40_RS01500	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CDC40_RS01515	COG0824	Thioesterase
CDC40_RS01525	COG0719	Fe-S assembly protein
CDC40_RS01545	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CDC40_RS01550	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CDC40_RS01560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDC40_RS01570	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDC40_RS01575	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CDC40_RS01580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDC40_RS01585	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CDC40_RS01590	COG1959	2 iron, 2 sulfur cluster binding
CDC40_RS01595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CDC40_RS01605	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CDC40_RS01610	COG1834	amidinotransferase
CDC40_RS01615	COG0544	peptidyl-prolyl cis-trans isomerase activity
CDC40_RS01620	COG0740	serine-type endopeptidase activity
CDC40_RS01625	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CDC40_RS01650	COG2226	methyltransferase
CDC40_RS01655	COG0589	response to stress
CDC40_RS01670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CDC40_RS01675	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDC40_RS01675	COG2022	thiamine diphosphate biosynthetic process
CDC40_RS01685	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CDC40_RS01690	COG0237	dephospho-CoA kinase activity
CDC40_RS01690	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDC40_RS01695	COG0745	RESPONSE REGULATOR receiver
CDC40_RS01720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDC40_RS01725	COG0463	Glycosyl transferase, family 2
CDC40_RS01735	COG0436	Aminotransferase
CDC40_RS01750	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CDC40_RS01760	COG2022	thiamine diphosphate biosynthetic process
CDC40_RS01785	COG0420	3'-5' exonuclease activity
CDC40_RS01795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDC40_RS01800	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CDC40_RS01805	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CDC40_RS01810	COG0848	biopolymer transport protein
CDC40_RS01815	COG0194	GDP metabolic process
CDC40_RS01830	COG0612	Peptidase, M16
CDC40_RS01835	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CDC40_RS01840	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CDC40_RS01845	COG0735	belongs to the Fur family
CDC40_RS01855	COG1619	proteins homologs of microcin C7 resistance protein MccF
CDC40_RS01860	COG1007	ATP synthesis coupled electron transport
CDC40_RS01865	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDC40_RS01865	COG0425	Belongs to the sulfur carrier protein TusA family
CDC40_RS01870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDC40_RS01875	COG0204	Acyl-transferase
CDC40_RS01875	COG0318	PFAM AMP-dependent synthetase and ligase
CDC40_RS01880	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CDC40_RS01885	COG0228	four-way junction DNA binding
CDC40_RS01895	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CDC40_RS01900	COG1702	phosphate starvation-inducible protein PhoH
CDC40_RS01925	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDC40_RS01940	COG0542	response to heat
CDC40_RS01955	COG0481	GTPase activity
CDC40_RS01965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CDC40_RS01990	COG0328	RNA-DNA hybrid ribonuclease activity
CDC40_RS01995	COG0222	ribosome binding
CDC40_RS02000	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CDC40_RS02005	COG0081	regulation of translation
CDC40_RS02010	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CDC40_RS02015	COG0250	Participates in transcription elongation, termination and antitermination
CDC40_RS02040	COG0629	single-stranded DNA binding
CDC40_RS02045	COG0446	pyridine nucleotide-disulphide oxidoreductase
CDC40_RS02060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDC40_RS02065	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CDC40_RS02070	COG1842	Phage shock protein A
CDC40_RS02080	COG0312	modulator of DNA gyrase
CDC40_RS02085	COG5398	heme oxygenase
CDC40_RS02090	COG0165	Argininosuccinate lyase
CDC40_RS02105	COG2203	Gaf domain
CDC40_RS02105	COG3706	GGDEF domain
CDC40_RS02105	COG5001	Diguanylate cyclase
CDC40_RS02105	COG4251	negative regulation of phosphorylation
CDC40_RS02110	COG0457	Tetratricopeptide repeat
CDC40_RS02110	COG0463	Glycosyl transferase, family 2
CDC40_RS02115	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CDC40_RS02120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CDC40_RS02135	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CDC40_RS02170	COG2119	membrane
CDC40_RS02190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CDC40_RS02210	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CDC40_RS02225	COG3411	Ferredoxin
CDC40_RS02235	COG3842	ATPase activity
CDC40_RS02255	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CDC40_RS02260	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CDC40_RS02270	COG1959	2 iron, 2 sulfur cluster binding
CDC40_RS02290	COG2082	Precorrin-8x methylmutase
CDC40_RS02300	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CDC40_RS02300	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDC40_RS02305	COG0217	transcriptional regulatory protein
CDC40_RS02320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CDC40_RS02325	COG0434	BtpA family
CDC40_RS02330	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CDC40_RS02335	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CDC40_RS02340	COG0484	heat shock protein binding
CDC40_RS02345	COG0788	formyltetrahydrofolate deformylase activity
CDC40_RS02350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CDC40_RS02355	COG0459	protein refolding
CDC40_RS02360	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CDC40_RS02365	COG0395	ABC-type sugar transport system, permease component
CDC40_RS02370	COG0004	ammonium transporteR
CDC40_RS02380	COG0285	dihydrofolate synthase activity
CDC40_RS02395	COG0735	belongs to the Fur family
CDC40_RS02410	COG2205	protein histidine kinase activity
CDC40_RS02445	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDC40_RS02450	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CDC40_RS02455	COG0022	dehydrogenase e1 component
CDC40_RS02455	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDC40_RS02465	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CDC40_RS02470	COG0625	glutathione transferase activity
CDC40_RS02480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CDC40_RS02480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CDC40_RS02490	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDC40_RS02495	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CDC40_RS02500	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CDC40_RS02505	COG1132	(ABC) transporter
CDC40_RS02510	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CDC40_RS02525	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CDC40_RS02535	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CDC40_RS02540	COG1012	belongs to the aldehyde dehydrogenase family
CDC40_RS02545	COG4178	(ABC) transporter
CDC40_RS02560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CDC40_RS02565	COG1454	alcohol dehydrogenase
CDC40_RS02565	COG1012	belongs to the aldehyde dehydrogenase family
CDC40_RS02570	COG0095	Lipoate-protein ligase
CDC40_RS02585	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CDC40_RS02595	COG0140	phosphoribosyl-ATP diphosphatase activity
CDC40_RS02595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CDC40_RS02635	COG1215	transferase activity, transferring glycosyl groups
CDC40_RS02640	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CDC40_RS02645	COG0438	transferase activity, transferring glycosyl groups
CDC40_RS02735	COG1049	propionate catabolic process, 2-methylcitrate cycle
CDC40_RS02745	COG1192	Involved in chromosome partitioning
CDC40_RS02750	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CDC40_RS02760	COG1376	ErfK ybiS ycfS ynhG family protein
CDC40_RS02770	COG0408	coproporphyrinogen oxidase activity
CDC40_RS02775	COG1333	cytochrome c biogenesis protein
CDC40_RS02845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDC40_RS02850	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDC40_RS02855	COG0713	ATP synthesis coupled electron transport
CDC40_RS02860	COG0839	Belongs to the complex I subunit 6 family
CDC40_RS02865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDC40_RS02870	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CDC40_RS02875	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDC40_RS02880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDC40_RS02885	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CDC40_RS02890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CDC40_RS02895	COG0072	phenylalanine-tRNA ligase activity
CDC40_RS02895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CDC40_RS02900	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CDC40_RS02925	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CDC40_RS02930	COG0148	phosphopyruvate hydratase activity
CDC40_RS02935	COG2217	Heavy metal translocating P-type atpase
CDC40_RS02940	COG1187	pseudouridine synthase activity
CDC40_RS02945	COG1132	(ABC) transporter
CDC40_RS02960	COG0557	exoribonuclease II activity
CDC40_RS02980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CDC40_RS02985	COG0187	DNA topoisomerase II activity
CDC40_RS02985	COG1372	Participates in initiation and elongation during chromosome replication
CDC40_RS03000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDC40_RS03010	COG1136	(ABC) transporter
CDC40_RS03010	COG0577	efflux transmembrane transporter activity
CDC40_RS03015	COG0085	RNA polymerase activity
CDC40_RS03020	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDC40_RS03025	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CDC40_RS03030	COG0501	Belongs to the peptidase M48B family
CDC40_RS03060	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
CDC40_RS03065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDC40_RS03090	COG0612	Peptidase, M16
CDC40_RS03105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CDC40_RS03120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CDC40_RS03170	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CDC40_RS03170	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CDC40_RS03190	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CDC40_RS03195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CDC40_RS03210	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CDC40_RS03235	COG0515	serine threonine protein kinase
CDC40_RS03235	COG1357	PFAM Pentapeptide repeats (8 copies)
CDC40_RS03280	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CDC40_RS03295	COG0426	domain, Protein
CDC40_RS03295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDC40_RS03300	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CDC40_RS03340	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CDC40_RS03355	COG0363	glucosamine-6-phosphate deaminase activity
CDC40_RS03380	COG0740	serine-type endopeptidase activity
CDC40_RS03385	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CDC40_RS03390	COG0765	amino acid transport
CDC40_RS03405	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CDC40_RS03410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CDC40_RS03430	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CDC40_RS03450	COG0129	dihydroxy-acid dehydratase activity
CDC40_RS03455	COG2099	Precorrin-6x reductase
CDC40_RS03465	COG0667	Aldo Keto reductase
CDC40_RS03470	COG0742	ribosomal rna small subunit methyltransferase
CDC40_RS03500	COG0745	RESPONSE REGULATOR receiver
CDC40_RS03505	COG0438	transferase activity, transferring glycosyl groups
CDC40_RS03515	COG1073	alpha beta
CDC40_RS03515	COG2226	methyltransferase
CDC40_RS03520	COG2046	Belongs to the sulfate adenylyltransferase family
CDC40_RS03525	COG1472	Belongs to the glycosyl hydrolase 3 family
CDC40_RS03530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDC40_RS03535	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CDC40_RS03540	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CDC40_RS03555	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CDC40_RS03565	COG0175	sulfate reduction
CDC40_RS03570	COG0752	glycyl-tRNA synthetase alpha subunit
CDC40_RS03585	COG0163	prenyltransferase activity
CDC40_RS03595	COG0702	epimerase
CDC40_RS03605	COG1410	methionine synthase
CDC40_RS03605	COG0646	methionine synthase
CDC40_RS03615	COG2010	Cytochrome c
CDC40_RS03625	COG0457	Tetratricopeptide repeat
CDC40_RS03625	COG0463	Glycosyl transferase, family 2
CDC40_RS03630	COG2198	Histidine kinase
CDC40_RS03630	COG0784	Response regulator, receiver
CDC40_RS03630	COG5002	protein histidine kinase activity
CDC40_RS03635	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CDC40_RS03645	COG0745	RESPONSE REGULATOR receiver
CDC40_RS03655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CDC40_RS03660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CDC40_RS03665	COG0489	protein tyrosine kinase activity
CDC40_RS03670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDC40_RS03670	COG0519	Catalyzes the synthesis of GMP from XMP
CDC40_RS03685	COG4572	Cation transport regulator
CDC40_RS03690	COG0305	Participates in initiation and elongation during chromosome replication
CDC40_RS03690	COG1372	Participates in initiation and elongation during chromosome replication
CDC40_RS03690	COG0305	Participates in initiation and elongation during chromosome replication
CDC40_RS03690	COG1372	Participates in initiation and elongation during chromosome replication
CDC40_RS03695	COG0359	binds to the 23S rRNA
CDC40_RS03715	COG1555	photosystem II stabilization
CDC40_RS03720	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CDC40_RS03780	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CDC40_RS03785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CDC40_RS03785	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CDC40_RS03790	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDC40_RS03795	COG0372	Belongs to the citrate synthase family
CDC40_RS03800	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CDC40_RS03810	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CDC40_RS03815	COG0438	transferase activity, transferring glycosyl groups
CDC40_RS03835	COG3385	transposase activity
CDC40_RS03840	COG1836	PFAM Integral membrane protein DUF92
CDC40_RS03845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CDC40_RS03850	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CDC40_RS03880	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CDC40_RS03890	COG1840	ABC-type Fe3 transport system, periplasmic component
CDC40_RS03910	COG0469	pyruvate kinase activity
CDC40_RS03915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDC40_RS03920	COG0470	DNA polymerase III
CDC40_RS03925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CDC40_RS03925	COG0617	tRNA 3'-terminal CCA addition
CDC40_RS03925	COG0517	IMP dehydrogenase activity
CDC40_RS03940	COG1181	Belongs to the D-alanine--D-alanine ligase family
CDC40_RS03950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CDC40_RS03955	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CDC40_RS03965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDC40_RS03970	COG0312	modulator of DNA gyrase
CDC40_RS03975	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CDC40_RS03980	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CDC40_RS03990	COG0632	four-way junction helicase activity
CDC40_RS04005	COG0445	tRNA wobble uridine modification
CDC40_RS04010	COG0829	nickel cation binding
CDC40_RS04025	COG3409	Peptidoglycan-binding domain 1 protein
CDC40_RS04025	COG3429	Glucose-6-phosphate dehydrogenase subunit
CDC40_RS04030	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CDC40_RS04035	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CDC40_RS04075	COG2172	sigma factor antagonist activity
CDC40_RS04085	COG4251	negative regulation of phosphorylation
CDC40_RS04105	COG1132	(ABC) transporter
CDC40_RS04120	COG0693	protein deglycase activity
CDC40_RS04130	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CDC40_RS04135	COG0123	including yeast histone deacetylase and acetoin utilization protein
CDC40_RS04165	COG0784	Response regulator, receiver
CDC40_RS04170	COG3659	wide pore channel activity
CDC40_RS04175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDC40_RS04185	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CDC40_RS04190	COG1132	(ABC) transporter
CDC40_RS04195	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CDC40_RS04200	COG0167	dihydroorotate dehydrogenase activity
CDC40_RS04210	COG1122	ATPase activity
CDC40_RS04215	COG0438	transferase activity, transferring glycosyl groups
CDC40_RS04220	COG0574	Belongs to the PEP-utilizing enzyme family
CDC40_RS04220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CDC40_RS04225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CDC40_RS04235	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CDC40_RS04240	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CDC40_RS04250	COG0745	RESPONSE REGULATOR receiver
CDC40_RS04260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CDC40_RS04270	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CDC40_RS04295	COG1530	ribonuclease E activity
CDC40_RS04300	COG2066	Belongs to the glutaminase family
CDC40_RS04310	COG0706	membrane insertase activity
CDC40_RS04315	COG0594	ribonuclease P activity
CDC40_RS04320	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CDC40_RS04325	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CDC40_RS04335	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CDC40_RS04365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDC40_RS04370	COG0701	Predicted permease
CDC40_RS04375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CDC40_RS04380	COG0783	Belongs to the Dps family
CDC40_RS04395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDC40_RS04405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDC40_RS04410	COG0154	amidase activity
CDC40_RS04420	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDC40_RS04440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDC40_RS04460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDC40_RS04470	COG1216	Glycosyl transferase, family 2
CDC40_RS04480	COG0640	Transcriptional regulator
CDC40_RS04485	COG4968	Prepilin-type N-terminal cleavage methylation domain
CDC40_RS04500	COG0840	transmembrane signaling receptor activity
CDC40_RS04500	COG2203	Gaf domain
CDC40_RS04535	COG0411	ABC transporter
CDC40_RS04540	COG0559	Belongs to the binding-protein-dependent transport system permease family
CDC40_RS04555	COG0537	adenosine 5'-monophosphoramidase activity
CDC40_RS04560	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CDC40_RS04575	COG1216	Glycosyl transferase, family 2
CDC40_RS04585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CDC40_RS04590	COG1882	Formate acetyltransferase
CDC40_RS04605	COG1162	GTPase activity
CDC40_RS04615	COG1253	flavin adenine dinucleotide binding
CDC40_RS04625	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CDC40_RS04630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDC40_RS04635	COG0831	urea catabolic process
CDC40_RS04640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CDC40_RS04645	COG2048	Heterodisulfide reductase, subunit B
CDC40_RS04650	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CDC40_RS04670	COG4245	von Willebrand factor, type A
CDC40_RS04680	COG4245	von Willebrand factor, type A
CDC40_RS04695	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDC40_RS04700	COG1063	alcohol dehydrogenase
CDC40_RS04705	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CDC40_RS04720	COG0149	triose-phosphate isomerase activity
CDC40_RS04730	COG1192	Involved in chromosome partitioning
CDC40_RS04735	COG1132	(ABC) transporter
CDC40_RS04775	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CDC40_RS04780	COG0805	protein transport
CDC40_RS04785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CDC40_RS04795	COG1091	dTDP-4-dehydrorhamnose reductase activity
CDC40_RS04800	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDC40_RS04815	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CDC40_RS04820	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CDC40_RS04825	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
CDC40_RS04830	COG4451	ribulose bisphosphate carboxylase, small
CDC40_RS04830	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDC40_RS04835	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDC40_RS04840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CDC40_RS04885	COG0741	lytic transglycosylase activity
CDC40_RS04895	COG1028	Short-chain dehydrogenase reductase Sdr
CDC40_RS04900	COG0436	Aminotransferase
CDC40_RS04905	COG0552	protein localization to endoplasmic reticulum
CDC40_RS04910	COG1218	3'(2'),5'-bisphosphate nucleotidase
CDC40_RS04920	COG5002	protein histidine kinase activity
CDC40_RS04925	COG3706	GGDEF domain
CDC40_RS04925	COG2203	Gaf domain
CDC40_RS04925	COG4251	negative regulation of phosphorylation
CDC40_RS04925	COG5001	Diguanylate cyclase
CDC40_RS04935	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CDC40_RS04955	COG0596	Alpha beta hydrolase
CDC40_RS04970	COG1555	photosystem II stabilization
CDC40_RS04970	COG1234	tRNA 3'-trailer cleavage
CDC40_RS04995	COG1104	cysteine desulfurase activity
CDC40_RS05015	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CDC40_RS05020	COG0189	ligase activity
CDC40_RS05025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CDC40_RS05035	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDC40_RS05040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDC40_RS05065	COG2205	protein histidine kinase activity
CDC40_RS05070	COG0237	dephospho-CoA kinase activity
CDC40_RS05085	COG0602	queuosine metabolic process
CDC40_RS05100	COG1116	anion transmembrane transporter activity
CDC40_RS05105	COG0275	rRNA processing
CDC40_RS05110	COG1116	anion transmembrane transporter activity
CDC40_RS05125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CDC40_RS05135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDC40_RS05150	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CDC40_RS05160	COG0440	acetolactate synthase activity
CDC40_RS05170	COG1160	GTP binding
CDC40_RS05180	COG5002	protein histidine kinase activity
CDC40_RS05180	COG2205	protein histidine kinase activity
CDC40_RS05180	COG0784	Response regulator, receiver
CDC40_RS05185	COG0271	Belongs to the BolA IbaG family
CDC40_RS05190	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CDC40_RS05195	COG0071	Belongs to the small heat shock protein (HSP20) family
CDC40_RS05215	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CDC40_RS05220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDC40_RS05225	COG0316	Belongs to the HesB IscA family
CDC40_RS05255	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CDC40_RS05270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CDC40_RS05275	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDC40_RS05305	COG1045	serine acetyltransferase
CDC40_RS05310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDC40_RS05335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CDC40_RS05340	COG0416	fatty acid biosynthetic process
CDC40_RS05345	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CDC40_RS05370	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CDC40_RS05395	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CDC40_RS05400	COG0321	lipoyl(octanoyl) transferase activity
CDC40_RS05405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CDC40_RS05415	COG3264	Mechanosensitive ion channel
CDC40_RS05415	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CDC40_RS05435	COG0018	arginyl-trna synthetase
CDC40_RS05445	COG0717	Belongs to the dCTP deaminase family
CDC40_RS05450	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CDC40_RS05460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDC40_RS05470	COG1121	(ABC) transporter
CDC40_RS05475	COG1899	peptidyl-lysine modification to peptidyl-hypusine
CDC40_RS05485	COG2217	Heavy metal translocating P-type atpase
CDC40_RS05525	COG1063	alcohol dehydrogenase
CDC40_RS05550	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CDC40_RS05550	COG0758	DNA mediated transformation
CDC40_RS05555	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDC40_RS05560	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDC40_RS05575	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CDC40_RS05585	COG3063	Type IV pilus biogenesis stability protein PilW
CDC40_RS05590	COG0412	Dienelactone hydrolase
CDC40_RS05600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CDC40_RS05615	COG0310	cobalt ion transport
CDC40_RS05640	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CDC40_RS05640	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CDC40_RS05645	COG0459	protein refolding
CDC40_RS05650	COG2340	Cysteine-rich secretory protein family
CDC40_RS05665	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CDC40_RS05675	COG0793	Belongs to the peptidase S41A family
CDC40_RS05680	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CDC40_RS05690	COG1304	FMN binding
CDC40_RS05700	COG0121	glutamine amidotransferase
CDC40_RS05715	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
CDC40_RS05720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CDC40_RS05765	COG0542	response to heat
CDC40_RS05785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CDC40_RS05790	COG0193	aminoacyl-tRNA hydrolase activity
CDC40_RS05795	COG0577	efflux transmembrane transporter activity
CDC40_RS05795	COG1136	(ABC) transporter
CDC40_RS05800	COG0395	ABC-type sugar transport system, permease component
CDC40_RS05845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CDC40_RS05845	COG0426	domain, Protein
CDC40_RS05860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CDC40_RS05865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDC40_RS05870	COG0067	glutamate synthase
CDC40_RS05870	COG0070	glutamate synthase
CDC40_RS05870	COG0069	glutamate synthase activity
CDC40_RS05875	COG2205	protein histidine kinase activity
CDC40_RS05875	COG0784	Response regulator, receiver
CDC40_RS05880	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CDC40_RS05885	COG0830	nickel cation binding
CDC40_RS05890	COG0303	'Molybdopterin
CDC40_RS05895	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CDC40_RS05900	COG0315	cyclic pyranopterin monophosphate synthase activity
CDC40_RS05900	COG0746	molybdenum cofactor guanylyltransferase activity
CDC40_RS05905	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CDC40_RS05910	COG0314	molybdopterin synthase activity
CDC40_RS05915	COG0583	DNA-binding transcription factor activity
CDC40_RS05920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDC40_RS05935	COG0243	molybdopterin cofactor binding
CDC40_RS05940	COG1116	anion transmembrane transporter activity
CDC40_RS05945	COG1116	anion transmembrane transporter activity
CDC40_RS05945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDC40_RS05950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDC40_RS05955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDC40_RS05960	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CDC40_RS05985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CDC40_RS06010	COG0529	Catalyzes the synthesis of activated sulfate
CDC40_RS06015	COG1716	ATPase activity
CDC40_RS06015	COG0842	Transport permease protein
CDC40_RS06015	COG1131	(ABC) transporter
CDC40_RS06025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDC40_RS06025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CDC40_RS06030	COG0612	Peptidase, M16
CDC40_RS06035	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CDC40_RS06065	COG0156	8-amino-7-oxononanoate synthase activity
CDC40_RS06070	COG0745	RESPONSE REGULATOR receiver
CDC40_RS06075	COG1716	ATPase activity
CDC40_RS06075	COG0842	Transport permease protein
CDC40_RS06075	COG1131	(ABC) transporter
CDC40_RS06080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CDC40_RS06090	COG1357	PFAM Pentapeptide repeats (8 copies)
CDC40_RS06090	COG0515	serine threonine protein kinase
CDC40_RS06130	COG0358	DNA primase activity
CDC40_RS06135	COG0205	6-phosphofructokinase activity
CDC40_RS06140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDC40_RS06145	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CDC40_RS06155	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CDC40_RS06160	COG5322	oxidoreductase activity
CDC40_RS06165	COG0825	malonyl-CoA metabolic process
CDC40_RS06170	COG1028	Short-chain dehydrogenase reductase Sdr
CDC40_RS06175	COG0302	gtp cyclohydrolase
CDC40_RS06200	COG0517	IMP dehydrogenase activity
CDC40_RS06200	COG1994	Peptidase M50
CDC40_RS06210	COG0335	large ribosomal subunit rRNA binding
CDC40_RS06215	COG0424	maF-like protein
CDC40_RS06230	COG0508	dehydrogenase complex catalyzes the overall conversion of
CDC40_RS06235	COG1122	ATPase activity
CDC40_RS06240	COG1649	PFAM Uncharacterised BCR, COG1649
CDC40_RS06245	COG0028	Belongs to the TPP enzyme family
CDC40_RS06250	COG0511	ligase activity, forming carbon-carbon bonds
CDC40_RS06255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CDC40_RS06260	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CDC40_RS06270	COG1070	Carbohydrate kinase
CDC40_RS06275	COG1160	GTP binding
CDC40_RS06290	COG0649	NAD binding
CDC40_RS06295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDC40_RS06305	COG2010	Cytochrome c
CDC40_RS06310	COG2010	Cytochrome c
CDC40_RS06320	COG5002	protein histidine kinase activity
CDC40_RS06320	COG0784	Response regulator, receiver
CDC40_RS06320	COG2205	protein histidine kinase activity
CDC40_RS06325	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CDC40_RS06335	COG0360	Binds together with S18 to 16S ribosomal RNA
CDC40_RS06340	COG0179	Fumarylacetoacetate (FAA) hydrolase
CDC40_RS06350	COG1494	fructose-1,6-bisphosphatase
CDC40_RS06355	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CDC40_RS06365	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CDC40_RS06385	COG3631	Ketosteroid isomerase-related protein
CDC40_RS06400	COG2062	phosphohistidine phosphatase, SixA
CDC40_RS06415	COG0745	RESPONSE REGULATOR receiver
CDC40_RS06440	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CDC40_RS06460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CDC40_RS06470	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CDC40_RS06490	COG1441	menaquinone biosynthetic process
CDC40_RS06510	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CDC40_RS06520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CDC40_RS06520	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CDC40_RS06525	COG0339	signal peptide processing
CDC40_RS06530	COG0739	heme binding
CDC40_RS06535	COG0768	penicillin binding
CDC40_RS06545	COG0107	imidazoleglycerol-phosphate synthase activity
CDC40_RS06550	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CDC40_RS06555	COG0084	hydrolase, TatD family'
CDC40_RS06560	COG0268	Binds directly to 16S ribosomal RNA
CDC40_RS06565	COG1691	(AIR) carboxylase
CDC40_RS06580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CDC40_RS06585	COG1615	UPF0182 protein
CDC40_RS06590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDC40_RS06595	COG0457	Tetratricopeptide repeat
CDC40_RS06605	COG0601	transmembrane transport
CDC40_RS06610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDC40_RS06630	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CDC40_RS06635	COG0438	transferase activity, transferring glycosyl groups
CDC40_RS06635	COG0297	glycogen (starch) synthase activity
CDC40_RS06650	COG0515	serine threonine protein kinase
CDC40_RS06650	COG1357	PFAM Pentapeptide repeats (8 copies)
CDC40_RS06655	COG0583	DNA-binding transcription factor activity
CDC40_RS06660	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CDC40_RS06675	COG3706	GGDEF domain
CDC40_RS06680	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDC40_RS06695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CDC40_RS06700	COG5002	protein histidine kinase activity
CDC40_RS06705	COG1799	cell septum assembly
CDC40_RS06710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CDC40_RS06720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CDC40_RS06725	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CDC40_RS06735	COG0318	PFAM AMP-dependent synthetase and ligase
CDC40_RS06740	COG0799	negative regulation of ribosome biogenesis
CDC40_RS06765	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDC40_RS06780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CDC40_RS06785	COG0588	phosphoglycerate mutase activity
CDC40_RS06805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CDC40_RS06810	COG0066	3-isopropylmalate dehydratase activity
CDC40_RS06825	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CDC40_RS06835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDC40_RS06845	COG1606	tRNA processing
CDC40_RS06855	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CDC40_RS06855	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CDC40_RS06880	COG0523	cobalamin synthesis protein
CDC40_RS06910	COG0842	Transport permease protein
CDC40_RS06910	COG1131	(ABC) transporter
CDC40_RS06910	COG1716	ATPase activity
CDC40_RS06935	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CDC40_RS06950	COG0601	transmembrane transport
CDC40_RS06970	COG1850	ribulose-bisphosphate carboxylase activity
CDC40_RS06980	COG4451	ribulose bisphosphate carboxylase, small
CDC40_RS06985	COG0525	valine-tRNA ligase activity
CDC40_RS06990	COG1028	Short-chain dehydrogenase reductase Sdr
CDC40_RS07010	COG2319	Wd-40 repeat
CDC40_RS07010	COG1672	PFAM Archaeal ATPase
CDC40_RS07020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CDC40_RS07025	COG0837	glucose binding
CDC40_RS07040	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDC40_RS07050	COG0629	single-stranded DNA binding
CDC40_RS07070	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
CDC40_RS07085	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CDC40_RS07090	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CDC40_RS07115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDC40_RS07120	COG2211	Major facilitator Superfamily
CDC40_RS07125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CDC40_RS07135	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CDC40_RS07140	COG0457	Tetratricopeptide repeat
CDC40_RS07145	COG0589	response to stress
CDC40_RS07175	COG0406	alpha-ribazole phosphatase activity
CDC40_RS07180	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CDC40_RS07185	COG0114	fumarate hydratase activity
CDC40_RS07195	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CDC40_RS07210	COG0564	pseudouridine synthase activity
CDC40_RS07215	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDC40_RS07220	COG0515	serine threonine protein kinase
CDC40_RS07220	COG1357	PFAM Pentapeptide repeats (8 copies)
CDC40_RS07245	COG1175	transmembrane transport
CDC40_RS07250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CDC40_RS07255	COG0138	bifunctional purine biosynthesis protein purh
CDC40_RS07280	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CDC40_RS07285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CDC40_RS07300	COG0714	Associated with various cellular activities
CDC40_RS07305	COG0196	riboflavin kinase activity
CDC40_RS07315	COG0540	Belongs to the ATCase OTCase family
CDC40_RS07320	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CDC40_RS07325	COG1562	ergosterol biosynthetic process
CDC40_RS07330	COG0493	'glutamate synthase
CDC40_RS07330	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
CDC40_RS07345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDC40_RS07355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CDC40_RS07365	COG1366	Belongs to the anti-sigma-factor antagonist family
CDC40_RS07370	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CDC40_RS07380	COG1137	ATPase activity
CDC40_RS07410	COG0762	integral membrane protein
CDC40_RS07430	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CDC40_RS07450	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CDC40_RS07460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CDC40_RS07470	COG0277	FAD linked oxidase domain protein
CDC40_RS07485	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CDC40_RS07485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDC40_RS07495	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CDC40_RS07500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDC40_RS07510	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CDC40_RS07515	COG0037	tRNA processing
CDC40_RS07520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CDC40_RS07530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CDC40_RS07535	COG5001	Diguanylate cyclase
CDC40_RS07540	COG0336	Belongs to the RNA methyltransferase TrmD family
CDC40_RS07560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CDC40_RS07565	COG0793	Belongs to the peptidase S41A family
CDC40_RS07570	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CDC40_RS07580	COG2226	methyltransferase
CDC40_RS07585	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDC40_RS07585	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CDC40_RS07590	COG1271	oxidase subunit
CDC40_RS07595	COG1294	oxidase, subunit
CDC40_RS07600	COG0473	3-isopropylmalate dehydrogenase activity
CDC40_RS07615	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
CDC40_RS07620	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
CDC40_RS07630	COG0515	serine threonine protein kinase
CDC40_RS07645	COG0438	transferase activity, transferring glycosyl groups
CDC40_RS07650	COG0438	transferase activity, transferring glycosyl groups
CDC40_RS07660	COG0174	glutamine synthetase
CDC40_RS07665	COG0012	GTP binding
CDC40_RS07670	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CDC40_RS07675	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CDC40_RS07685	COG0772	Belongs to the SEDS family
CDC40_RS07695	COG1218	3'(2'),5'-bisphosphate nucleotidase
CDC40_RS07700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CDC40_RS07710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CDC40_RS07715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CDC40_RS07720	COG0750	zinc metalloprotease
CDC40_RS07725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CDC40_RS07740	COG0181	hydroxymethylbilane synthase activity
CDC40_RS07760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDC40_RS07790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CDC40_RS07795	COG0483	inositol monophosphate 1-phosphatase activity
CDC40_RS07805	COG5002	protein histidine kinase activity
CDC40_RS07810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDC40_RS07825	COG0247	lactate metabolic process
CDC40_RS07830	COG0277	FAD linked oxidase domain protein
CDC40_RS07845	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CDC40_RS07865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CDC40_RS07870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CDC40_RS07890	COG0242	peptide deformylase activity
CDC40_RS07900	COG0509	glycine decarboxylation via glycine cleavage system
CDC40_RS07905	COG0559	Belongs to the binding-protein-dependent transport system permease family
CDC40_RS07920	COG0454	-acetyltransferase
CDC40_RS07925	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDC40_RS07930	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CDC40_RS07945	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CDC40_RS07950	COG0052	Belongs to the universal ribosomal protein uS2 family
CDC40_RS07955	COG1192	Involved in chromosome partitioning
CDC40_RS07960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CDC40_RS07980	COG1842	Phage shock protein A
CDC40_RS07985	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CDC40_RS07995	COG4447	cellulose binding
CDC40_RS08000	COG1773	rubredoxin
CDC40_RS08005	COG1489	DNA binding
CDC40_RS08040	COG0357	Ribosomal RNA small subunit methyltransferase G
CDC40_RS08050	COG3659	wide pore channel activity
CDC40_RS08055	COG2003	Belongs to the UPF0758 family
CDC40_RS08060	COG2326	polyphosphate kinase activity
CDC40_RS08070	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CDC40_RS08080	COG1178	ABC-type Fe3 transport system permease component
CDC40_RS08085	COG0157	Belongs to the NadC ModD family
CDC40_RS08090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CDC40_RS08100	COG1492	cobalamin metabolic process
CDC40_RS08125	COG5398	heme oxygenase
CDC40_RS08130	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CDC40_RS08150	COG2226	methyltransferase
CDC40_RS08155	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDC40_RS08155	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CDC40_RS08180	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CDC40_RS08185	COG0443	Heat shock 70 kDa protein
CDC40_RS08200	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CDC40_RS08200	COG3264	Mechanosensitive ion channel
CDC40_RS08205	COG0792	nuclease activity
CDC40_RS08210	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CDC40_RS08230	COG1528	Iron-storage protein
CDC40_RS08235	COG3977	Valine--pyruvate aminotransferase
CDC40_RS08240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CDC40_RS08250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CDC40_RS08255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CDC40_RS08260	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CDC40_RS08265	COG0049	tRNA binding
CDC40_RS08270	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CDC40_RS08275	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CDC40_RS08280	COG0051	transcription antitermination factor activity, RNA binding
CDC40_RS08290	COG0322	excinuclease ABC activity
CDC40_RS08300	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CDC40_RS08305	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDC40_RS08310	COG3842	ATPase activity
CDC40_RS08315	COG0142	geranyltranstransferase activity
CDC40_RS08320	COG1316	TRANSCRIPTIONal
CDC40_RS08325	COG0740	serine-type endopeptidase activity
CDC40_RS08335	COG0019	diaminopimelate decarboxylase activity
CDC40_RS08345	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CDC40_RS08350	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CDC40_RS08355	COG0083	homoserine kinase activity
CDC40_RS08375	COG1136	(ABC) transporter
CDC40_RS08390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CDC40_RS08395	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CDC40_RS08395	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CDC40_RS08400	COG0860	N-Acetylmuramoyl-L-alanine amidase
CDC40_RS08415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CDC40_RS08455	COG4372	Transposase
CDC40_RS08465	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CDC40_RS08485	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CDC40_RS08490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CDC40_RS08495	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDC40_RS08500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CDC40_RS08510	COG1215	transferase activity, transferring glycosyl groups
CDC40_RS08515	COG1215	transferase activity, transferring glycosyl groups
CDC40_RS08525	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CDC40_RS08535	COG4636	protein conserved in cyanobacteria
CDC40_RS08540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CDC40_RS08545	COG2843	Capsule synthesis protein
CDC40_RS08550	COG0517	IMP dehydrogenase activity
CDC40_RS08550	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CDC40_RS08560	COG0616	signal peptide processing
CDC40_RS08575	COG1166	arginine decarboxylase activity
CDC40_RS08580	COG0439	Biotin carboxylase
CDC40_RS08585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDC40_RS08590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CDC40_RS08595	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CDC40_RS08625	COG0651	ATP synthesis coupled electron transport
CDC40_RS08635	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDC40_RS08645	COG3001	Fructosamine kinase
CDC40_RS08650	COG0681	Belongs to the peptidase S26 family
CDC40_RS08665	COG2154	pterin-4-alpha-carbinolamine dehydratase
CDC40_RS08670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CDC40_RS08675	COG0215	cysteine-tRNA ligase activity
CDC40_RS08680	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CDC40_RS08685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CDC40_RS08695	COG1716	ATPase activity
CDC40_RS08695	COG5001	Diguanylate cyclase
CDC40_RS08700	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDC40_RS08705	COG0527	aspartate kinase activity
CDC40_RS08710	COG0697	spore germination
CDC40_RS08720	COG2890	protein-(glutamine-N5) methyltransferase activity
CDC40_RS08740	COG0151	Belongs to the GarS family
CDC40_RS08750	COG1136	(ABC) transporter
CDC40_RS08755	COG0003	Pfam Anion-transporting ATPase
CDC40_RS08770	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
CDC40_RS08785	COG1797	cobyrinic acid a,c-diamide synthase activity
CDC40_RS08790	COG0739	heme binding
CDC40_RS08800	COG0653	protein targeting
CDC40_RS08815	COG1215	transferase activity, transferring glycosyl groups
CDC40_RS08820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDC40_RS08855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CDC40_RS08880	COG1982	Orn Lys Arg decarboxylase major
CDC40_RS08885	COG3906	Belongs to the UPF0473 family
CDC40_RS08900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CDC40_RS08905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CDC40_RS08910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CDC40_RS08915	COG0557	exoribonuclease II activity
CDC40_RS08920	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CDC40_RS08930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDC40_RS08955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CDC40_RS08955	COG1754	DNA topoisomerase type I activity
CDC40_RS08965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CDC40_RS08990	COG0789	Transcriptional regulator
CDC40_RS09005	COG4221	oxidoreductase activity
CDC40_RS09015	COG0109	protoheme IX farnesyltransferase activity
CDC40_RS09020	COG1612	heme a metabolic process
CDC40_RS09040	COG0124	histidyl-tRNA synthetase
CDC40_RS09045	COG0497	DNA recombination
CDC40_RS09055	COG1131	(ABC) transporter
CDC40_RS09060	COG3693	PFAM glycoside hydrolase, family 10
CDC40_RS09070	COG0396	ATPase activity
CDC40_RS09075	COG0719	Fe-S assembly protein
CDC40_RS09085	COG3128	pkhd-type hydroxylase
CDC40_RS09095	COG5002	protein histidine kinase activity
CDC40_RS09105	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CDC40_RS09110	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CDC40_RS09120	COG0572	uridine kinase
CDC40_RS09125	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CDC40_RS09150	COG2217	Heavy metal translocating P-type atpase
CDC40_RS09170	COG0730	response to heat
CDC40_RS09175	COG0492	ferredoxin-NADP+ reductase activity
CDC40_RS09180	COG1196	nuclear chromosome segregation
CDC40_RS09190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CDC40_RS09195	COG0800	Aldolase
CDC40_RS09205	COG1215	transferase activity, transferring glycosyl groups
CDC40_RS09215	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDC40_RS09225	COG0195	Participates in both transcription termination and antitermination
CDC40_RS09230	COG0779	Required for maturation of 30S ribosomal subunits
CDC40_RS09245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CDC40_RS09275	COG0352	thiamine-phosphate diphosphorylase activity
CDC40_RS09280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDC40_RS09285	COG0354	folic acid binding
CDC40_RS09295	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CDC40_RS09305	COG2226	methyltransferase
CDC40_RS09320	COG1573	uracil-dna glycosylase
CDC40_RS09335	COG0237	dephospho-CoA kinase activity
CDC40_RS09340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CDC40_RS09345	COG1413	lyase activity
CDC40_RS09350	COG1413	lyase activity
CDC40_RS09355	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDC40_RS09360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CDC40_RS09365	COG0237	dephospho-CoA kinase activity
CDC40_RS09380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CDC40_RS09385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CDC40_RS09385	COG0519	Catalyzes the synthesis of GMP from XMP
CDC40_RS09390	COG0525	valine-tRNA ligase activity
CDC40_RS09395	COG2308	Evidence 4 Homologs of previously reported genes of
CDC40_RS09405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CDC40_RS09410	COG1543	Belongs to the glycosyl hydrolase 57 family
CDC40_RS09415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CDC40_RS09430	COG0033	Phosphoglucomutase
CDC40_RS09435	COG0420	3'-5' exonuclease activity
CDC40_RS09455	COG1234	tRNA 3'-trailer cleavage
CDC40_RS09465	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CDC40_RS09475	COG0004	ammonium transporteR
CDC40_RS09485	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CDC40_RS09495	COG2205	protein histidine kinase activity
CDC40_RS09505	COG1126	abc transporter atp-binding protein
CDC40_RS09520	COG1872	DUF167
CDC40_RS09530	COG0180	Tryptophanyl-tRNA synthetase
CDC40_RS09550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDC40_RS09555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CDC40_RS09560	COG1116	anion transmembrane transporter activity
CDC40_RS09560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CDC40_RS09565	COG1116	anion transmembrane transporter activity
CDC40_RS09620	COG0515	serine threonine protein kinase
CDC40_RS09630	COG0850	regulation of cytokinetic process
CDC40_RS09635	COG2894	cell division
CDC40_RS09640	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CDC40_RS09650	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CDC40_RS09680	COG0857	belongs to the CobB CobQ family
CDC40_RS09700	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDC40_RS09705	COG2045	Belongs to the ComB family
CDC40_RS09715	COG0681	Belongs to the peptidase S26 family
CDC40_RS09730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CDC40_RS09750	COG0569	domain protein
CDC40_RS09765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CDC40_RS09770	COG1012	belongs to the aldehyde dehydrogenase family
CDC40_RS09780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CDC40_RS09780	COG0438	transferase activity, transferring glycosyl groups
CDC40_RS09795	COG0431	NADPH-dependent FMN reductase
CDC40_RS09800	COG0113	porphobilinogen synthase activity
CDC40_RS09810	COG0024	Methionine aminopeptidase
CDC40_RS09815	COG0415	Belongs to the DNA photolyase family
CDC40_RS09825	COG1366	Belongs to the anti-sigma-factor antagonist family
CDC40_RS09830	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CDC40_RS09840	COG0356	it plays a direct role in the translocation of protons across the membrane
CDC40_RS09845	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDC40_RS09850	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDC40_RS09855	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CDC40_RS09860	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CDC40_RS09865	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CDC40_RS09870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CDC40_RS09875	COG5002	protein histidine kinase activity
CDC40_RS09885	COG0159	tryptophan synthase activity
CDC40_RS09890	COG0772	Belongs to the SEDS family
CDC40_RS09895	COG4172	Belongs to the ABC transporter superfamily
CDC40_RS09905	COG0515	serine threonine protein kinase
CDC40_RS09910	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDC40_RS09925	COG0475	glutathione-regulated potassium exporter activity
CDC40_RS09930	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CDC40_RS09935	COG0802	atpase or kinase
CDC40_RS09940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDC40_RS09945	COG2177	Part of the ABC transporter FtsEX involved in
CDC40_RS09950	COG2884	Cell division ATP-binding protein ftsE
CDC40_RS09995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CDC40_RS10000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CDC40_RS10010	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CDC40_RS10015	COG0316	Belongs to the HesB IscA family
CDC40_RS10020	COG1090	epimerase
CDC40_RS10030	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CDC40_RS10055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CDC40_RS10075	COG0077	Prephenate dehydratase
CDC40_RS10080	COG0686	Belongs to the AlaDH PNT family
CDC40_RS10085	COG0575	Belongs to the CDS family
CDC40_RS10090	COG1595	DNA-templated transcription, initiation
CDC40_RS10100	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CDC40_RS10115	COG0411	ABC transporter
CDC40_RS10125	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CDC40_RS10135	COG1725	Transcriptional regulator
CDC40_RS10140	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CDC40_RS10150	COG0483	inositol monophosphate 1-phosphatase activity
CDC40_RS10175	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDC40_RS10180	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDC40_RS10190	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CDC40_RS10195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CDC40_RS10200	COG1546	Belongs to the CinA family
CDC40_RS10200	COG1058	Belongs to the CinA family
CDC40_RS10230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CDC40_RS10280	COG3937	granule-associated protein
CDC40_RS10290	COG2094	Belongs to the DNA glycosylase MPG family
CDC40_RS10300	COG0484	heat shock protein binding
CDC40_RS10305	COG0443	Heat shock 70 kDa protein
CDC40_RS10315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDC40_RS10315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CDC40_RS10325	COG0739	heme binding
CDC40_RS10330	COG1587	Uroporphyrinogen-III synthase
CDC40_RS10340	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CDC40_RS10345	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CDC40_RS10350	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CDC40_RS10360	COG2302	S4 RNA-binding domain
CDC40_RS10375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CDC40_RS10380	COG0573	inorganic phosphate transmembrane transporter activity
CDC40_RS10385	COG0573	inorganic phosphate transmembrane transporter activity
CDC40_RS10390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CDC40_RS10405	COG0189	ligase activity
CDC40_RS10405	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CDC40_RS10435	COG0419	ATPase involved in DNA repair
CDC40_RS10440	COG2304	oxidoreductase activity
CDC40_RS10450	COG1028	Short-chain dehydrogenase reductase Sdr
CDC40_RS10465	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CDC40_RS10465	COG0546	phosphoglycolate phosphatase activity
CDC40_RS10470	COG0330	HflC and HflK could
CDC40_RS10475	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CDC40_RS10485	COG0047	phosphoribosylformylglycinamidine synthase activity
CDC40_RS10490	COG2095	MarC family integral membrane protein
CDC40_RS10495	COG0741	lytic transglycosylase activity
CDC40_RS10495	COG0791	NLP P60 protein
CDC40_RS10500	COG0516	GMP reductase activity
CDC40_RS10510	COG0751	glycine-tRNA ligase activity
CDC40_RS10515	COG1185	polyribonucleotide nucleotidyltransferase activity
CDC40_RS10540	COG1575	Belongs to the MenA family. Type 1 subfamily
CDC40_RS10550	COG0456	acetyltransferase
CDC40_RS10555	COG0778	Nitroreductase
CDC40_RS10560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CDC40_RS10565	COG0745	RESPONSE REGULATOR receiver
CDC40_RS10570	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CDC40_RS10575	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CDC40_RS10580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CDC40_RS10590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDC40_RS10595	COG3781	membrane
CDC40_RS10600	COG2217	Heavy metal translocating P-type atpase
CDC40_RS10630	COG0443	Heat shock 70 kDa protein
CDC40_RS10635	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CDC40_RS10650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CDC40_RS10665	COG0515	serine threonine protein kinase
CDC40_RS10665	COG2815	serine threonine protein kinase
CDC40_RS10675	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CDC40_RS10680	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CDC40_RS10690	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CDC40_RS10720	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CDC40_RS10735	COG1381	Involved in DNA repair and RecF pathway recombination
CDC40_RS10745	COG2208	phosphoserine phosphatase activity
CDC40_RS10765	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CDC40_RS10775	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDC40_RS10780	COG0631	protein serine/threonine phosphatase activity
CDC40_RS10790	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CDC40_RS10845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CDC40_RS10855	COG2255	four-way junction helicase activity
CDC40_RS10860	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CDC40_RS10865	COG0724	RNA recognition motif
CDC40_RS10870	COG0482	sulfurtransferase activity
CDC40_RS10885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CDC40_RS10890	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CDC40_RS10895	COG0450	alkyl hydroperoxide reductase
CDC40_RS10905	COG0628	permease
CDC40_RS10915	COG0006	proline dipeptidase activity
CDC40_RS10920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CDC40_RS10925	COG0776	regulation of translation
CDC40_RS10930	COG0126	phosphoglycerate kinase activity
CDC40_RS10935	COG0589	response to stress
CDC40_RS10950	COG0135	phosphoribosylanthranilate isomerase activity
CDC40_RS10965	COG0469	pyruvate kinase activity
CDC40_RS10970	COG0523	cobalamin synthesis protein
CDC40_RS11010	COG1217	gtp-binding protein TYPA
CDC40_RS11020	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CDC40_RS11025	COG3118	belongs to the thioredoxin family
CDC40_RS11030	COG4399	Belongs to the UPF0754 family
CDC40_RS11040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CDC40_RS11045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CDC40_RS11050	COG5505	Protein of unknown function (DUF819)
CDC40_RS11065	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CDC40_RS11075	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CDC40_RS11120	COG4279	zinc finger
CDC40_RS11125	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CDC40_RS11130	COG1496	oxidoreductase activity
CDC40_RS11140	COG1657	PFAM Prenyltransferase squalene oxidase
CDC40_RS11145	COG4783	chaperone-mediated protein folding
CDC40_RS11160	COG0529	Catalyzes the synthesis of activated sulfate
CDC40_RS11165	COG0110	maltose O-acetyltransferase activity
CDC40_RS11200	COG1216	Glycosyl transferase, family 2
CDC40_RS11205	COG1215	transferase activity, transferring glycosyl groups
CDC40_RS11215	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CDC40_RS11230	COG0556	nucleotide-excision repair
CDC40_RS11240	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CDC40_RS11250	COG0583	DNA-binding transcription factor activity
CDC40_RS11260	COG0170	dolichyl monophosphate biosynthetic process
CDC40_RS11265	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CDC40_RS11280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CDC40_RS11290	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CDC40_RS11295	COG0539	negative regulation of cytoplasmic translation
CDC40_RS11300	COG1970	mechanosensitive ion channel activity
CDC40_RS11310	COG3158	transport of potassium into the cell
CDC40_RS11315	COG0436	Aminotransferase
CDC40_RS11320	COG0371	Dehydrogenase
CDC40_RS11330	COG2022	thiamine diphosphate biosynthetic process
CDC40_RS11330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CDC40_RS11340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CDC40_RS11345	COG0587	DNA-directed DNA polymerase activity
CDC40_RS11365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CDC40_RS11370	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CDC40_RS11375	COG3443	Belongs to the bacterial solute-binding protein 9 family
CDC40_RS11375	COG0803	Belongs to the bacterial solute-binding protein 9 family
CDC40_RS11380	COG1121	(ABC) transporter
CDC40_RS11395	COG0596	Alpha beta hydrolase
CDC40_RS11405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDC40_RS11410	COG0587	DNA-directed DNA polymerase activity
CDC40_RS11435	COG0275	rRNA processing
CDC40_RS11465	COG3932	Exopolysaccharide synthesis, ExoD
CDC40_RS11475	COG0058	SHG alpha-glucan phosphorylase activity
CDC40_RS11485	COG0714	Associated with various cellular activities
CDC40_RS11515	COG3118	belongs to the thioredoxin family
CDC40_RS11525	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CDC40_RS11545	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CDC40_RS11550	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDC40_RS11570	COG0495	leucyl-tRNA aminoacylation
CDC40_RS11595	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CDC40_RS11600	COG1331	Highly conserved protein containing a thioredoxin domain
CDC40_RS11605	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CDC40_RS11625	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CDC40_RS11630	COG3854	ATPases associated with a variety of cellular activities
CDC40_RS11640	COG1191	sigma factor activity
CDC40_RS11645	COG1968	undecaprenyl-diphosphatase activity
CDC40_RS11655	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CDC40_RS11660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDC40_RS11665	COG0668	transmembrane transport
CDC40_RS11670	COG2885	chlorophyll binding
CDC40_RS11680	COG0251	oxidation-reduction process
CDC40_RS11710	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CDC40_RS11720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CDC40_RS11725	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDC40_RS11735	COG0166	Belongs to the GPI family
CDC40_RS11745	COG0617	tRNA 3'-terminal CCA addition
CDC40_RS11760	COG0137	argininosuccinate synthase activity
CDC40_RS11765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CDC40_RS11780	COG1640	4-alpha-glucanotransferase
CDC40_RS11795	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CDC40_RS11800	COG1446	asparaginase
CDC40_RS11815	COG3046	protein related to deoxyribodipyrimidine photolyase
CDC40_RS11820	COG0134	indole-3-glycerol-phosphate synthase activity
CDC40_RS11825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CDC40_RS11835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CDC40_RS11850	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CDC40_RS11855	COG1132	(ABC) transporter
CDC40_RS11860	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CDC40_RS11865	COG0644	oxidoreductase
CDC40_RS11875	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CDC40_RS11880	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CDC40_RS11890	COG0038	chloride channel
CDC40_RS11895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CDC40_RS11900	COG0009	L-threonylcarbamoyladenylate synthase
CDC40_RS11905	COG4243	Vitamin k epoxide reductase
CDC40_RS11910	COG1672	PFAM Archaeal ATPase
CDC40_RS11915	COG2814	Major facilitator Superfamily
CDC40_RS11930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CDC40_RS11950	COG0131	Imidazoleglycerol-phosphate dehydratase
CDC40_RS11955	COG0484	heat shock protein binding
CDC40_RS11960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDC40_RS11970	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CDC40_RS11980	COG0419	ATPase involved in DNA repair
CDC40_RS12010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CDC40_RS12020	COG1459	type II secretion system
CDC40_RS12025	COG0484	heat shock protein binding
CDC40_RS12040	COG1104	cysteine desulfurase activity
CDC40_RS12050	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
CDC40_RS12060	COG2957	Belongs to the agmatine deiminase family
CDC40_RS12065	COG0254	rRNA binding
CDC40_RS12070	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CDC40_RS12075	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CDC40_RS12080	COG0101	tRNA pseudouridine synthase activity
CDC40_RS12085	COG0203	ribosomal protein L17
CDC40_RS12090	COG0202	RNA polymerase activity
CDC40_RS12095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CDC40_RS12100	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CDC40_RS12105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CDC40_RS12110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CDC40_RS12115	COG0563	adenylate kinase activity
CDC40_RS12120	COG0201	protein transport
CDC40_RS12125	COG0200	Binds to the 23S rRNA
CDC40_RS12130	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CDC40_RS12135	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CDC40_RS12140	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CDC40_RS12145	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CDC40_RS12150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CDC40_RS12155	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CDC40_RS12160	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CDC40_RS12165	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CDC40_RS12170	COG0255	Belongs to the universal ribosomal protein uL29 family
CDC40_RS12175	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CDC40_RS12180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CDC40_RS12185	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CDC40_RS12190	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CDC40_RS12195	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CDC40_RS12200	COG0089	rRNA binding
CDC40_RS12205	COG0088	Forms part of the polypeptide exit tunnel
CDC40_RS12210	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CDC40_RS12215	COG0343	queuine tRNA-ribosyltransferase activity
CDC40_RS12235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CDC40_RS12250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CDC40_RS12255	COG0628	permease
CDC40_RS12270	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CDC40_RS12275	COG1940	carbohydrate kinase activity
CDC40_RS12280	COG1316	TRANSCRIPTIONal
CDC40_RS12285	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CDC40_RS12295	COG5002	protein histidine kinase activity
CDC40_RS12300	COG0728	peptidoglycan biosynthetic process
CDC40_RS12305	COG0592	DNA-directed DNA polymerase activity
CDC40_RS12315	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CDC40_RS12325	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
CDC40_RS12350	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CDC40_RS12360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CDC40_RS12365	COG2252	PERMEase
CDC40_RS12390	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CDC40_RS12395	COG2052	Domain of unknown function (DUF370)
CDC40_RS12400	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CDC40_RS12405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CDC40_RS12415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CDC40_RS12420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CDC40_RS12430	COG3659	wide pore channel activity
CDC40_RS12435	COG2197	response regulator
CDC40_RS12460	COG0284	orotidine-5'-phosphate decarboxylase activity
CDC40_RS12475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CDC40_RS12485	COG2385	sporulation resulting in formation of a cellular spore
CDC40_RS12495	COG0233	cytoplasmic translational termination
CDC40_RS12500	COG0528	UMP kinase activity
CDC40_RS12510	COG0745	RESPONSE REGULATOR receiver
CDC40_RS12520	COG1192	Involved in chromosome partitioning
CDC40_RS12525	COG0542	response to heat
CDC40_RS12575	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CDC40_RS12580	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CDC40_RS12590	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CDC40_RS12595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CDC40_RS12600	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CDC40_RS12605	COG3536	Protein conserved in bacteria
CDC40_RS12625	COG1193	negative regulation of DNA recombination
CDC40_RS12630	COG0017	Asparaginyl-tRNA synthetase
CDC40_RS12635	COG0589	response to stress
CDC40_RS12635	COG0475	glutathione-regulated potassium exporter activity
CDC40_RS12640	COG0133	tryptophan synthase activity
CDC40_RS12650	COG0131	Imidazoleglycerol-phosphate dehydratase