locus-tag	class	description
TPET_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TPET_RS00010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TPET_RS00025	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TPET_RS00025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TPET_RS00030	COG0741	lytic transglycosylase activity
TPET_RS00045	COG0840	transmembrane signaling receptor activity
TPET_RS00050	COG0306	phosphate transporter
TPET_RS00060	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TPET_RS00065	COG1392	Phosphate transport regulator
TPET_RS00070	COG3956	TIGRFAM MazG family protein
TPET_RS00080	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TPET_RS00085	COG1684	flagellar biosynthetic protein fliR
TPET_RS00090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TPET_RS00095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TPET_RS00100	COG1419	protein localization to endoplasmic reticulum
TPET_RS00105	COG0455	bacterial-type flagellum organization
TPET_RS00115	COG1776	CheC inhibitor of MCP methylation
TPET_RS00120	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
TPET_RS00125	COG1191	sigma factor activity
TPET_RS00150	COG2359	stage V sporulation protein S
TPET_RS00155	COG1085	galactose-1-phosphate uridylyltransferase
TPET_RS00160	COG0297	glycogen (starch) synthase activity
TPET_RS00170	COG1968	undecaprenyl-diphosphatase activity
TPET_RS00175	COG2239	Acts as a magnesium transporter
TPET_RS00180	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TPET_RS00185	COG0750	zinc metalloprotease
TPET_RS00190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TPET_RS00200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TPET_RS00220	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
TPET_RS00225	COG2873	o-acetylhomoserine
TPET_RS00230	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
TPET_RS00235	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
TPET_RS00245	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TPET_RS00245	COG0674	pyruvate-flavodoxin oxidoreductase activity
TPET_RS00250	COG0148	phosphopyruvate hydratase activity
TPET_RS00255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TPET_RS00265	COG1214	PFAM Peptidase M22, glycoprotease
TPET_RS00270	COG0542	response to heat
TPET_RS00275	COG0275	rRNA processing
TPET_RS00285	COG0768	penicillin binding
TPET_RS00290	COG0492	ferredoxin-NADP+ reductase activity
TPET_RS00315	COG1234	tRNA 3'-trailer cleavage
TPET_RS00320	COG0359	binds to the 23S rRNA
TPET_RS00330	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TPET_RS00335	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TPET_RS00340	COG1862	Preprotein translocase
TPET_RS00355	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TPET_RS00360	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TPET_RS00365	COG1639	'signal transduction protein
TPET_RS00370	COG5002	protein histidine kinase activity
TPET_RS00375	COG0009	L-threonylcarbamoyladenylate synthase
TPET_RS00385	COG1420	regulation of RNA biosynthetic process
TPET_RS00390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TPET_RS00395	COG0484	heat shock protein binding
TPET_RS00400	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TPET_RS00405	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TPET_RS00410	COG0295	cytidine deaminase activity
TPET_RS00415	COG4535	Mg2 and Co2 transporter CorC
TPET_RS00420	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
TPET_RS00430	COG2201	protein-glutamate methylesterase activity
TPET_RS00445	COG0772	Belongs to the SEDS family
TPET_RS00455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
TPET_RS00460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TPET_RS00465	COG0849	cell division
TPET_RS00475	COG0187	DNA topoisomerase II activity
TPET_RS00485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TPET_RS00490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TPET_RS00505	COG3842	ATPase activity
TPET_RS00510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TPET_RS00525	COG0072	phenylalanine-tRNA ligase activity
TPET_RS00525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TPET_RS00530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TPET_RS00540	COG1979	alcohol dehydrogenase
TPET_RS00550	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
TPET_RS00575	COG0534	Mate efflux family protein
TPET_RS00585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TPET_RS00590	COG0395	ABC-type sugar transport system, permease component
TPET_RS00605	COG1472	Belongs to the glycosyl hydrolase 3 family
TPET_RS00610	COG1846	Transcriptional regulator
TPET_RS00610	COG1940	carbohydrate kinase activity
TPET_RS00615	COG0450	alkyl hydroperoxide reductase
TPET_RS00625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TPET_RS00630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TPET_RS00635	COG0504	CTP synthase activity
TPET_RS00640	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TPET_RS00645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TPET_RS00650	COG2070	2-Nitropropane dioxygenase
TPET_RS00655	COG1268	BioY protein
TPET_RS00660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TPET_RS00665	COG2045	Belongs to the ComB family
TPET_RS00690	COG1131	(ABC) transporter
TPET_RS00695	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
TPET_RS00700	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
TPET_RS00705	COG0351	phosphomethylpyrimidine kinase
TPET_RS00705	COG1992	Thiamine-phosphate synthase
TPET_RS00715	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TPET_RS00720	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
TPET_RS00730	COG1659	Linocin_M18 bacteriocin protein
TPET_RS00775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TPET_RS00790	COG1774	PSP1 C-terminal conserved region
TPET_RS00800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TPET_RS00805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TPET_RS00810	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
TPET_RS00815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TPET_RS00825	COG1131	(ABC) transporter
TPET_RS00835	COG0393	Putative heavy-metal-binding
TPET_RS00840	COG0052	Belongs to the universal ribosomal protein uS2 family
TPET_RS00865	COG0463	Glycosyl transferase, family 2
TPET_RS00865	COG0457	Tetratricopeptide repeat
TPET_RS00875	COG0426	domain, Protein
TPET_RS00880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TPET_RS00885	COG2226	methyltransferase
TPET_RS00890	COG1486	melibiose metabolic process
TPET_RS00900	COG0572	uridine kinase
TPET_RS00915	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TPET_RS00920	COG0793	Belongs to the peptidase S41A family
TPET_RS00935	COG0438	transferase activity, transferring glycosyl groups
TPET_RS00945	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
TPET_RS00950	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TPET_RS00955	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TPET_RS00960	COG2199	diguanylate cyclase activity
TPET_RS00960	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TPET_RS00975	COG1482	cell wall glycoprotein biosynthetic process
TPET_RS00985	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
TPET_RS01000	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TPET_RS01005	COG1490	D-aminoacyl-tRNA deacylase activity
TPET_RS01010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TPET_RS01025	COG0312	modulator of DNA gyrase
TPET_RS01030	COG0312	modulator of DNA gyrase
TPET_RS01050	COG0557	exoribonuclease II activity
TPET_RS01055	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TPET_RS01060	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TPET_RS01065	COG0215	cysteine-tRNA ligase activity
TPET_RS01070	COG0835	chemotaxis
TPET_RS01075	COG0511	ligase activity, forming carbon-carbon bonds
TPET_RS01075	COG5016	pyruvate
TPET_RS01085	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TPET_RS01090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TPET_RS01090	COG0617	tRNA 3'-terminal CCA addition
TPET_RS01090	COG3620	sequence-specific DNA binding
TPET_RS01120	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TPET_RS01125	COG0095	Lipoate-protein ligase
TPET_RS01130	COG0357	Ribosomal RNA small subunit methyltransferase G
TPET_RS01140	COG1136	(ABC) transporter
TPET_RS01145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TPET_RS01150	COG1058	Belongs to the CinA family
TPET_RS01150	COG1546	Belongs to the CinA family
TPET_RS01155	COG0643	Histidine kinase
TPET_RS01155	COG2198	Histidine kinase
TPET_RS01160	COG0835	chemotaxis
TPET_RS01165	COG2201	protein-glutamate methylesterase activity
TPET_RS01175	COG1338	Plays a role in the flagellum-specific transport system
TPET_RS01190	COG0740	serine-type endopeptidase activity
TPET_RS01195	COG0544	peptidyl-prolyl cis-trans isomerase activity
TPET_RS01205	COG0736	holo-[acyl-carrier-protein] synthase activity
TPET_RS01210	COG2890	protein-(glutamine-N5) methyltransferase activity
TPET_RS01220	COG0149	triose-phosphate isomerase activity
TPET_RS01220	COG0126	phosphoglycerate kinase activity
TPET_RS01225	COG0126	phosphoglycerate kinase activity
TPET_RS01230	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TPET_RS01235	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TPET_RS01240	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TPET_RS01270	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TPET_RS01270	COG1776	CheC inhibitor of MCP methylation
TPET_RS01275	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TPET_RS01285	COG1360	Flagellar Motor Protein
TPET_RS01295	COG1582	Flagellar protein (FlbD)
TPET_RS01335	COG0084	hydrolase, TatD family'
TPET_RS01340	COG1045	serine acetyltransferase
TPET_RS01345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TPET_RS01360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TPET_RS01370	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
TPET_RS01375	COG1773	rubredoxin
TPET_RS01380	COG2033	superoxide reductase activity
TPET_RS01385	COG1592	Rubrerythrin
TPET_RS01390	COG1476	TRANSCRIPTIONal
TPET_RS01395	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TPET_RS01400	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TPET_RS01405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TPET_RS01415	COG0561	phosphatase activity
TPET_RS01430	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TPET_RS01435	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TPET_RS01495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TPET_RS01540	COG0438	transferase activity, transferring glycosyl groups
TPET_RS01540	COG0297	glycogen (starch) synthase activity
TPET_RS01560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TPET_RS01570	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TPET_RS01575	COG0629	single-stranded DNA binding
TPET_RS01580	COG0360	Binds together with S18 to 16S ribosomal RNA
TPET_RS01605	COG0395	ABC-type sugar transport system, permease component
TPET_RS01610	COG1175	transmembrane transport
TPET_RS01620	COG2252	PERMEase
TPET_RS01625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TPET_RS01630	COG0765	amino acid transport
TPET_RS01655	COG1077	Cell shape determining protein MreB Mrl
TPET_RS01660	COG0517	IMP dehydrogenase activity
TPET_RS01660	COG1227	inorganic diphosphatase activity
TPET_RS01665	COG0697	spore germination
TPET_RS01670	COG0673	inositol 2-dehydrogenase activity
TPET_RS01695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TPET_RS01710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TPET_RS01715	COG0456	acetyltransferase
TPET_RS01720	COG2176	DNA-directed DNA polymerase activity
TPET_RS01725	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TPET_RS01730	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TPET_RS01735	COG0815	Transfers the fatty acyl group on membrane lipoproteins
TPET_RS01740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TPET_RS01745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TPET_RS01750	COG0552	protein localization to endoplasmic reticulum
TPET_RS01760	COG3584	3D domain protein
TPET_RS01765	COG1959	2 iron, 2 sulfur cluster binding
TPET_RS01775	COG1489	DNA binding
TPET_RS01800	COG1181	Belongs to the D-alanine--D-alanine ligase family
TPET_RS01805	COG0598	Magnesium transport protein CorA
TPET_RS01820	COG0505	Belongs to the CarA family
TPET_RS01825	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TPET_RS01830	COG0473	3-isopropylmalate dehydrogenase activity
TPET_RS01835	COG0066	3-isopropylmalate dehydratase activity
TPET_RS01840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TPET_RS01845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TPET_RS01850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TPET_RS01855	COG0129	dihydroxy-acid dehydratase activity
TPET_RS01860	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TPET_RS01865	COG0440	acetolactate synthase activity
TPET_RS01870	COG0028	Belongs to the TPP enzyme family
TPET_RS01875	COG0527	aspartate kinase activity
TPET_RS01880	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TPET_RS01885	COG0083	homoserine kinase activity
TPET_RS01890	COG1131	(ABC) transporter
TPET_RS01905	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
TPET_RS01905	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
TPET_RS01915	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TPET_RS01925	COG4717	serine-type aminopeptidase activity
TPET_RS01940	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TPET_RS01945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TPET_RS01950	COG0601	transmembrane transport
TPET_RS01955	COG0747	negative chemotaxis
TPET_RS01960	COG4608	Belongs to the ABC transporter superfamily
TPET_RS01965	COG2608	mercury ion transmembrane transporter activity
TPET_RS01970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TPET_RS01975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TPET_RS01980	COG1923	regulation of RNA biosynthetic process
TPET_RS01985	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TPET_RS01990	COG2136	Putative SAM-dependent methyltransferase
TPET_RS01990	COG2521	methyltransferase
TPET_RS02005	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TPET_RS02010	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TPET_RS02015	COG0482	sulfurtransferase activity
TPET_RS02040	COG1242	4 iron, 4 sulfur cluster binding
TPET_RS02045	COG0442	prolyl-tRNA aminoacylation
TPET_RS02050	COG0606	chelatase, subunit chli
TPET_RS02060	COG1573	uracil-dna glycosylase
TPET_RS02075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TPET_RS02075	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TPET_RS02080	COG0459	protein refolding
TPET_RS02085	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TPET_RS02090	COG0601	transmembrane transport
TPET_RS02095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TPET_RS02100	COG0444	Belongs to the ABC transporter superfamily
TPET_RS02105	COG4608	Belongs to the ABC transporter superfamily
TPET_RS02115	COG0444	Belongs to the ABC transporter superfamily
TPET_RS02130	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
TPET_RS02135	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TPET_RS02145	COG0180	Tryptophanyl-tRNA synthetase
TPET_RS02155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TPET_RS02160	COG1595	DNA-templated transcription, initiation
TPET_RS02165	COG2890	protein-(glutamine-N5) methyltransferase activity
TPET_RS02170	COG2151	metal-sulfur cluster biosynthetic enzyme
TPET_RS02180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TPET_RS02185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TPET_RS02190	COG1116	anion transmembrane transporter activity
TPET_RS02220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TPET_RS02225	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TPET_RS02230	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TPET_RS02235	COG1196	nuclear chromosome segregation
TPET_RS02250	COG1335	isochorismatase
TPET_RS02260	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
TPET_RS02265	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
TPET_RS02285	COG0745	RESPONSE REGULATOR receiver
TPET_RS02295	COG0217	transcriptional regulatory protein
TPET_RS02305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
TPET_RS02310	COG0564	pseudouridine synthase activity
TPET_RS02315	COG0587	DNA-directed DNA polymerase activity
TPET_RS02325	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TPET_RS02330	COG0085	RNA polymerase activity
TPET_RS02335	COG0222	ribosome binding
TPET_RS02340	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TPET_RS02345	COG0081	regulation of translation
TPET_RS02350	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TPET_RS02355	COG0250	Participates in transcription elongation, termination and antitermination
TPET_RS02360	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TPET_RS02370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TPET_RS02395	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TPET_RS02400	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TPET_RS02405	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
TPET_RS02410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TPET_RS02415	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TPET_RS02420	COG1027	Aspartate ammonia-lyase
TPET_RS02425	COG1070	Carbohydrate kinase
TPET_RS02435	COG1028	Short-chain dehydrogenase reductase Sdr
TPET_RS02445	COG1802	Transcriptional regulator
TPET_RS02450	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TPET_RS02470	COG0601	transmembrane transport
TPET_RS02475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TPET_RS02480	COG0444	Belongs to the ABC transporter superfamily
TPET_RS02485	COG4608	Belongs to the ABC transporter superfamily
TPET_RS02490	COG3250	beta-galactosidase activity
TPET_RS02495	COG1902	pentaerythritol trinitrate reductase activity
TPET_RS02520	COG0371	Dehydrogenase
TPET_RS02530	COG3842	ATPase activity
TPET_RS02535	COG3833	ABC-type maltose transport systems, permease component
TPET_RS02540	COG1175	transmembrane transport
TPET_RS02550	COG1082	Xylose isomerase domain protein TIM barrel
TPET_RS02560	COG0673	inositol 2-dehydrogenase activity
TPET_RS02565	COG1402	creatininase
TPET_RS02570	COG1063	alcohol dehydrogenase
TPET_RS02585	COG0739	heme binding
TPET_RS02590	COG2201	protein-glutamate methylesterase activity
TPET_RS02605	COG1013	pyruvate-flavodoxin oxidoreductase activity
TPET_RS02615	COG0347	Belongs to the P(II) protein family
TPET_RS02620	COG0004	ammonium transporteR
TPET_RS02625	COG1435	thymidine kinase activity
TPET_RS02630	COG5002	protein histidine kinase activity
TPET_RS02630	COG3850	Histidine kinase
TPET_RS02645	COG0067	glutamate synthase
TPET_RS02655	COG0493	'glutamate synthase
TPET_RS02655	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
TPET_RS02675	COG0438	transferase activity, transferring glycosyl groups
TPET_RS02685	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TPET_RS02690	COG0446	pyridine nucleotide-disulphide oxidoreductase
TPET_RS02705	COG1194	a g-specific adenine glycosylase
TPET_RS02710	COG0778	Nitroreductase
TPET_RS02725	COG0778	Nitroreductase
TPET_RS02740	COG1131	(ABC) transporter
TPET_RS02745	COG0730	response to heat
TPET_RS02750	COG4869	propanediol catabolic process
TPET_RS02755	COG0071	Belongs to the small heat shock protein (HSP20) family
TPET_RS02760	COG0443	Heat shock 70 kDa protein
TPET_RS02770	COG1438	arginine binding
TPET_RS02775	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
TPET_RS02790	COG0840	transmembrane signaling receptor activity
TPET_RS02800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TPET_RS02805	COG1362	aminopeptidase activity
TPET_RS02810	COG0366	Alpha amylase catalytic
TPET_RS02820	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
TPET_RS02830	COG3956	TIGRFAM MazG family protein
TPET_RS02835	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TPET_RS02840	COG0438	transferase activity, transferring glycosyl groups
TPET_RS02845	COG1597	lipid kinase activity
TPET_RS02860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TPET_RS02875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TPET_RS02880	COG1136	(ABC) transporter
TPET_RS02885	COG0577	efflux transmembrane transporter activity
TPET_RS02885	COG1136	(ABC) transporter
TPET_RS02895	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TPET_RS02900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TPET_RS02900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TPET_RS02910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TPET_RS02915	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TPET_RS02925	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TPET_RS02950	COG1032	radical SAM domain protein
TPET_RS02955	COG1073	alpha beta
TPET_RS02960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TPET_RS02965	COG0543	2 iron, 2 sulfur cluster binding
TPET_RS02970	COG0167	dihydroorotate dehydrogenase activity
TPET_RS02975	COG0284	orotidine-5'-phosphate decarboxylase activity
TPET_RS02980	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TPET_RS02985	COG1574	metal-dependent hydrolase with the TIM-barrel fold
TPET_RS03005	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TPET_RS03010	COG1737	Transcriptional regulator
TPET_RS03015	COG1028	Short-chain dehydrogenase reductase Sdr
TPET_RS03020	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TPET_RS03030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TPET_RS03045	COG2217	Heavy metal translocating P-type atpase
TPET_RS03065	COG0667	Aldo Keto reductase
TPET_RS03085	COG0747	negative chemotaxis
TPET_RS03090	COG1501	Belongs to the glycosyl hydrolase 31 family
TPET_RS03110	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TPET_RS03115	COG1063	alcohol dehydrogenase
TPET_RS03120	COG1028	Short-chain dehydrogenase reductase Sdr
TPET_RS03125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TPET_RS03130	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TPET_RS03135	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TPET_RS03140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TPET_RS03145	COG0066	3-isopropylmalate dehydratase activity
TPET_RS03150	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TPET_RS03155	COG0372	Belongs to the citrate synthase family
TPET_RS03160	COG0205	6-phosphofructokinase activity
TPET_RS03165	COG1132	(ABC) transporter
TPET_RS03170	COG1132	(ABC) transporter
TPET_RS03180	COG0371	Dehydrogenase
TPET_RS03185	COG1070	Carbohydrate kinase
TPET_RS03190	COG0235	Class ii aldolase
TPET_RS03200	COG3534	alpha-L-arabinofuranosidase
TPET_RS03215	COG0395	ABC-type sugar transport system, permease component
TPET_RS03220	COG1175	transmembrane transport
TPET_RS03230	COG3507	Belongs to the glycosyl hydrolase 43 family
TPET_RS03240	COG3507	Belongs to the glycosyl hydrolase 43 family
TPET_RS03265	COG0395	ABC-type sugar transport system, permease component
TPET_RS03270	COG1175	transmembrane transport
TPET_RS03280	COG2160	L-arabinose isomerase activity
TPET_RS03290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
TPET_RS03295	COG0191	fructose-bisphosphate aldolase activity
TPET_RS03300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TPET_RS03300	COG0574	Belongs to the PEP-utilizing enzyme family
TPET_RS03310	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TPET_RS03310	COG0646	methionine synthase
TPET_RS03320	COG1410	methionine synthase
TPET_RS03320	COG0646	methionine synthase
TPET_RS03325	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TPET_RS03330	COG0776	regulation of translation
TPET_RS03335	COG0322	excinuclease ABC activity
TPET_RS03340	COG1187	pseudouridine synthase activity
TPET_RS03345	COG0445	tRNA wobble uridine modification
TPET_RS03350	COG0592	DNA-directed DNA polymerase activity
TPET_RS03355	COG0306	phosphate transporter
TPET_RS03365	COG1181	Belongs to the D-alanine--D-alanine ligase family
TPET_RS03370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TPET_RS03375	COG3481	metal-dependent phosphohydrolase, HD sub domain
TPET_RS03390	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TPET_RS03395	COG0792	nuclease activity
TPET_RS03400	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TPET_RS03405	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
TPET_RS03410	COG0758	DNA mediated transformation
TPET_RS03415	COG2878	Part of a membrane complex involved in electron transport
TPET_RS03425	COG4660	Part of a membrane complex involved in electron transport
TPET_RS03435	COG4658	electron transport chain
TPET_RS03440	COG4656	Part of a membrane complex involved in electron transport
TPET_RS03460	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TPET_RS03465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TPET_RS03475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TPET_RS03480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TPET_RS03485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TPET_RS03490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TPET_RS03495	COG0772	Belongs to the SEDS family
TPET_RS03500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TPET_RS03505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TPET_RS03535	COG2515	1-aminocyclopropane-1-carboxylate deaminase
TPET_RS03540	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
TPET_RS03540	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
TPET_RS03550	COG1122	ATPase activity
TPET_RS03555	COG1766	The M ring may be actively involved in energy transduction
TPET_RS03560	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TPET_RS03570	COG1157	protein secretion by the type III secretion system
TPET_RS03575	COG0751	glycine-tRNA ligase activity
TPET_RS03580	COG0752	glycyl-tRNA synthetase alpha subunit
TPET_RS03585	COG0251	oxidation-reduction process
TPET_RS03590	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TPET_RS03595	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TPET_RS03600	COG0509	glycine decarboxylation via glycine cleavage system
TPET_RS03605	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TPET_RS03615	COG0205	6-phosphofructokinase activity
TPET_RS03620	COG0469	pyruvate kinase activity
TPET_RS03625	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TPET_RS03630	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
TPET_RS03635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TPET_RS03660	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
TPET_RS03665	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TPET_RS03670	COG0542	response to heat
TPET_RS03675	COG0037	tRNA processing
TPET_RS03700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TPET_RS03705	COG0390	transport system, permease component
TPET_RS03730	COG2359	stage V sporulation protein S
TPET_RS03735	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TPET_RS03740	COG4139	cobalamin transport
TPET_RS03745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TPET_RS03775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TPET_RS03785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TPET_RS03830	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TPET_RS03835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TPET_RS03845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TPET_RS03850	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TPET_RS03855	COG1110	DNA topoisomerase II activity
TPET_RS03860	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TPET_RS03865	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
TPET_RS03875	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TPET_RS03880	COG0495	leucyl-tRNA aminoacylation
TPET_RS03885	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
TPET_RS03890	COG0285	dihydrofolate synthase activity
TPET_RS03895	COG0632	four-way junction helicase activity
TPET_RS03925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TPET_RS03930	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TPET_RS03945	COG1785	Belongs to the alkaline phosphatase family
TPET_RS03970	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TPET_RS03975	COG0416	fatty acid biosynthetic process
TPET_RS03980	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TPET_RS03985	COG0799	negative regulation of ribosome biogenesis
TPET_RS03990	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TPET_RS03995	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TPET_RS04015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TPET_RS04020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TPET_RS04020	COG0512	Glutamine amidotransferase of anthranilate synthase
TPET_RS04025	COG0134	indole-3-glycerol-phosphate synthase activity
TPET_RS04030	COG0135	phosphoribosylanthranilate isomerase activity
TPET_RS04035	COG0133	tryptophan synthase activity
TPET_RS04040	COG0159	tryptophan synthase activity
TPET_RS04045	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TPET_RS04055	COG0492	ferredoxin-NADP+ reductase activity
TPET_RS04060	COG1335	isochorismatase
TPET_RS04065	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TPET_RS04095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TPET_RS04100	COG1121	(ABC) transporter
TPET_RS04105	COG0803	Belongs to the bacterial solute-binding protein 9 family
TPET_RS04115	COG1509	lysine 2,3-aminomutase activity
TPET_RS04120	COG0778	Nitroreductase
TPET_RS04140	COG1070	Carbohydrate kinase
TPET_RS04145	COG1129	ABC transporter
TPET_RS04160	COG1172	Belongs to the binding-protein-dependent transport system permease family
TPET_RS04170	COG1940	carbohydrate kinase activity
TPET_RS04180	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TPET_RS04195	COG1079	Belongs to the binding-protein-dependent transport system permease family
TPET_RS04200	COG4603	Belongs to the binding-protein-dependent transport system permease family
TPET_RS04205	COG3845	ABC transporter
TPET_RS04210	COG1744	ABC transporter substrate-binding protein PnrA-like
TPET_RS04220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TPET_RS04230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TPET_RS04235	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TPET_RS04240	COG3116	cell division
TPET_RS04240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TPET_RS04245	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
TPET_RS04250	COG1459	type II secretion system
TPET_RS04285	COG1355	regulation of microtubule-based process
TPET_RS04290	COG0728	peptidoglycan biosynthetic process
TPET_RS04310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TPET_RS04315	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
TPET_RS04320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TPET_RS04325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TPET_RS04330	COG1120	ATPase activity
TPET_RS04335	COG3458	cephalosporin-C deacetylase activity
TPET_RS04340	COG1472	Belongs to the glycosyl hydrolase 3 family
TPET_RS04345	COG4608	Belongs to the ABC transporter superfamily
TPET_RS04350	COG0444	Belongs to the ABC transporter superfamily
TPET_RS04355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TPET_RS04360	COG0601	transmembrane transport
TPET_RS04375	COG1312	Catalyzes the dehydration of D-mannonate
TPET_RS04380	COG0246	Mannitol dehydrogenase
TPET_RS04390	COG0800	Aldolase
TPET_RS04395	COG1414	Transcriptional regulator
TPET_RS04400	COG1904	glucuronate isomerase
TPET_RS04415	COG3693	PFAM glycoside hydrolase, family 10
TPET_RS04420	COG0601	transmembrane transport
TPET_RS04425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TPET_RS04430	COG0444	Belongs to the ABC transporter superfamily
TPET_RS04435	COG4608	Belongs to the ABC transporter superfamily
TPET_RS04440	COG0747	negative chemotaxis
TPET_RS04445	COG3661	Belongs to the glycosyl hydrolase 67 family
TPET_RS04465	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TPET_RS04465	COG1918	ferrous iron import across plasma membrane
TPET_RS04475	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
TPET_RS04485	COG0675	Transposase, IS605 OrfB family
TPET_RS04500	COG1132	(ABC) transporter
TPET_RS04505	COG0006	proline dipeptidase activity
TPET_RS04510	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TPET_RS04510	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TPET_RS04515	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TPET_RS04520	COG1469	GTP cyclohydrolase I activity
TPET_RS04525	COG0720	synthase
TPET_RS04535	COG1618	nucleotide phosphatase activity, acting on free nucleotides
TPET_RS04560	COG4166	transmembrane transport
TPET_RS04565	COG0601	transmembrane transport
TPET_RS04575	COG0444	Belongs to the ABC transporter superfamily
TPET_RS04580	COG4608	Belongs to the ABC transporter superfamily
TPET_RS04590	COG1472	Belongs to the glycosyl hydrolase 3 family
TPET_RS04600	COG0840	transmembrane signaling receptor activity
TPET_RS04605	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TPET_RS04610	COG1993	acr, cog1993
TPET_RS04615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TPET_RS04620	COG1028	Short-chain dehydrogenase reductase Sdr
TPET_RS04625	COG1013	pyruvate-flavodoxin oxidoreductase activity
TPET_RS04630	COG0674	pyruvate-flavodoxin oxidoreductase activity
TPET_RS04635	COG1144	Oxidoreductase
TPET_RS04640	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TPET_RS04675	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TPET_RS04685	COG4948	Mandelate Racemase Muconate Lactonizing
TPET_RS04695	COG0737	Belongs to the 5'-nucleotidase family
TPET_RS04705	COG0622	Phosphoesterase
TPET_RS04710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TPET_RS04715	COG1278	Cold shock
TPET_RS04725	COG0432	Pfam Uncharacterised protein family UPF0047
TPET_RS04735	COG2894	cell division
TPET_RS04740	COG1067	ATP-dependent peptidase activity
TPET_RS04745	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TPET_RS04750	COG0039	L-malate dehydrogenase activity
TPET_RS04760	COG1515	deoxyribonuclease V activity
TPET_RS04775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TPET_RS04780	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TPET_RS04785	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TPET_RS04790	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TPET_RS04795	COG2137	regulation of response to DNA damage stimulus
TPET_RS04800	COG1418	mRNA catabolic process
TPET_RS04830	COG0395	ABC-type sugar transport system, permease component
TPET_RS04855	COG3459	Glycosyltransferase 36 associated
TPET_RS04860	COG2723	6-phospho-beta-galactosidase activity
TPET_RS04870	COG1653	transport
TPET_RS04885	COG1940	carbohydrate kinase activity
TPET_RS04895	COG1523	belongs to the glycosyl hydrolase 13 family
TPET_RS04900	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TPET_RS04920	COG0366	Alpha amylase catalytic
TPET_RS04925	COG2182	Extracellular solute-binding protein
TPET_RS04930	COG1175	transmembrane transport
TPET_RS04935	COG3833	ABC-type maltose transport systems, permease component
TPET_RS04940	COG0366	Alpha amylase catalytic
TPET_RS04945	COG1486	melibiose metabolic process
TPET_RS04950	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
TPET_RS04980	COG3437	response regulator, receiver
TPET_RS04985	COG1278	Cold shock
TPET_RS04990	COG0254	rRNA binding
TPET_RS04995	COG1185	polyribonucleotide nucleotidyltransferase activity
TPET_RS05000	COG1376	ErfK ybiS ycfS ynhG family protein
TPET_RS05005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TPET_RS05010	COG1758	RNA polymerase activity
TPET_RS05015	COG0194	GDP metabolic process
TPET_RS05020	COG2052	Domain of unknown function (DUF370)
TPET_RS05040	COG0301	tRNA thio-modification
TPET_RS05055	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TPET_RS05060	COG0436	Aminotransferase
TPET_RS05065	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TPET_RS05085	COG1368	sulfuric ester hydrolase activity
TPET_RS05095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TPET_RS05100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TPET_RS05105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TPET_RS05115	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TPET_RS05120	COG1660	Displays ATPase and GTPase activities
TPET_RS05135	COG1739	Uncharacterized protein family UPF0029
TPET_RS05140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TPET_RS05145	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TPET_RS05155	COG1162	GTPase activity
TPET_RS05160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TPET_RS05165	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TPET_RS05190	COG1028	Short-chain dehydrogenase reductase Sdr
TPET_RS05195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TPET_RS05215	COG2255	four-way junction helicase activity
TPET_RS05220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TPET_RS05230	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TPET_RS05235	COG0704	Plays a role in the regulation of phosphate uptake
TPET_RS05245	COG0305	Participates in initiation and elongation during chromosome replication
TPET_RS05250	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TPET_RS05265	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
TPET_RS05270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TPET_RS05275	COG0647	UMP catabolic process
TPET_RS05280	COG0667	Aldo Keto reductase
TPET_RS05285	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
TPET_RS05295	COG3426	butyrate kinase activity
TPET_RS05300	COG0280	phosphate acetyltransferase
TPET_RS05340	COG0556	nucleotide-excision repair
TPET_RS05345	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TPET_RS05350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TPET_RS05360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TPET_RS05365	COG2759	Belongs to the formate--tetrahydrofolate ligase family
TPET_RS05370	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TPET_RS05375	COG1570	exodeoxyribonuclease VII activity
TPET_RS05380	COG1722	exodeoxyribonuclease VII activity
TPET_RS05385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TPET_RS05395	COG1461	Dihydroxyacetone kinase
TPET_RS05405	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TPET_RS05415	COG0735	belongs to the Fur family
TPET_RS05420	COG0195	Participates in both transcription termination and antitermination
TPET_RS05425	COG0779	Required for maturation of 30S ribosomal subunits
TPET_RS05435	COG0137	argininosuccinate synthase activity
TPET_RS05440	COG0165	Argininosuccinate lyase
TPET_RS05445	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TPET_RS05450	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TPET_RS05455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TPET_RS05460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TPET_RS05505	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TPET_RS05510	COG1518	maintenance of DNA repeat elements
TPET_RS05545	COG0484	heat shock protein binding
TPET_RS05575	COG1337	RAMP superfamily
TPET_RS05585	COG1353	crispr-associated protein
TPET_RS05610	COG0525	valine-tRNA ligase activity
TPET_RS05615	COG2059	Chromate
TPET_RS05625	COG0519	Catalyzes the synthesis of GMP from XMP
TPET_RS05625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TPET_RS05630	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
TPET_RS05635	COG0330	HflC and HflK could
TPET_RS05640	COG0330	HflC and HflK could
TPET_RS05650	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TPET_RS05655	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TPET_RS05655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TPET_RS05660	COG0307	riboflavin synthase, alpha
TPET_RS05665	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TPET_RS05665	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TPET_RS05670	COG3706	GGDEF domain
TPET_RS05700	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TPET_RS05725	COG2115	Belongs to the xylose isomerase family
TPET_RS05730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TPET_RS05740	COG2813	Specifically methylates the guanine in position
TPET_RS05745	COG1122	ATPase activity
TPET_RS05750	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TPET_RS05755	COG0242	peptide deformylase activity
TPET_RS05770	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TPET_RS05775	COG0268	Binds directly to 16S ribosomal RNA
TPET_RS05785	COG0745	RESPONSE REGULATOR receiver
TPET_RS05790	COG5002	protein histidine kinase activity
TPET_RS05805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TPET_RS05820	COG1713	HD superfamily hydrolase involved in NAD metabolism
TPET_RS05835	COG0157	Belongs to the NadC ModD family
TPET_RS05840	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TPET_RS05845	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
TPET_RS05850	COG0540	Belongs to the ATCase OTCase family
TPET_RS05850	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
TPET_RS05855	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
TPET_RS05865	COG0543	2 iron, 2 sulfur cluster binding
TPET_RS05870	COG4555	ABC transporter
TPET_RS05880	COG0419	ATPase involved in DNA repair
TPET_RS05885	COG0420	3'-5' exonuclease activity
TPET_RS05895	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TPET_RS05900	COG0802	atpase or kinase
TPET_RS05915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TPET_RS05920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TPET_RS05925	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TPET_RS05930	COG0193	aminoacyl-tRNA hydrolase activity
TPET_RS05945	COG0481	GTPase activity
TPET_RS05955	COG0584	glycerophosphoryl diester phosphodiesterase
TPET_RS05965	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TPET_RS05965	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TPET_RS05970	COG1406	Chemotaxis phosphatase CheX
TPET_RS05985	COG0356	it plays a direct role in the translocation of protons across the membrane
TPET_RS05990	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TPET_RS05995	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TPET_RS06000	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TPET_RS06005	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
TPET_RS06010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
TPET_RS06015	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
TPET_RS06020	COG0355	proton-transporting ATP synthase activity, rotational mechanism
TPET_RS06035	COG1530	ribonuclease E activity
TPET_RS06040	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TPET_RS06045	COG0528	UMP kinase activity
TPET_RS06050	COG0477	Major facilitator Superfamily
TPET_RS06055	COG1827	regulation of RNA biosynthetic process
TPET_RS06060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TPET_RS06075	COG1595	DNA-templated transcription, initiation
TPET_RS06085	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TPET_RS06090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TPET_RS06100	COG0489	protein tyrosine kinase activity
TPET_RS06105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TPET_RS06110	COG0291	Belongs to the bacterial ribosomal protein bL35 family
TPET_RS06115	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TPET_RS06145	COG2203	Gaf domain
TPET_RS06145	COG2199	diguanylate cyclase activity
TPET_RS06160	COG2379	hydroxypyruvate reductase
TPET_RS06165	COG1040	competence protein
TPET_RS06190	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TPET_RS06195	COG0653	protein targeting
TPET_RS06205	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
TPET_RS06215	COG0101	tRNA pseudouridine synthase activity
TPET_RS06225	COG0681	Belongs to the peptidase S26 family
TPET_RS06230	COG0335	large ribosomal subunit rRNA binding
TPET_RS06235	COG4752	Belongs to the RNA methyltransferase TrmD family
TPET_RS06240	COG0336	Belongs to the RNA methyltransferase TrmD family
TPET_RS06245	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TPET_RS06250	COG1837	Belongs to the UPF0109 family
TPET_RS06255	COG0228	four-way junction DNA binding
TPET_RS06260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TPET_RS06265	COG1254	Belongs to the acylphosphatase family
TPET_RS06280	COG0343	queuine tRNA-ribosyltransferase activity
TPET_RS06290	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TPET_RS06300	COG2003	Belongs to the UPF0758 family
TPET_RS06305	COG0424	maF-like protein
TPET_RS06320	COG1477	protein flavinylation
TPET_RS06330	COG2078	PFAM AMMECR1 domain protein
TPET_RS06335	COG3872	metal-dependent enzyme
TPET_RS06340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TPET_RS06345	COG1086	Polysaccharide biosynthesis protein
TPET_RS06350	COG1078	dGTPase activity
TPET_RS06355	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
TPET_RS06355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TPET_RS06370	COG4786	Flagellar basal body rod
TPET_RS06385	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
TPET_RS06390	COG1706	bacterial-type flagellum-dependent cell motility
TPET_RS06400	COG1032	radical SAM domain protein
TPET_RS06425	COG0644	oxidoreductase
TPET_RS06430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TPET_RS06435	COG2086	electron transfer activity
TPET_RS06445	COG1575	Belongs to the MenA family. Type 1 subfamily
TPET_RS06450	COG1959	2 iron, 2 sulfur cluster binding
TPET_RS06480	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
TPET_RS06490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TPET_RS06495	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
TPET_RS06500	COG2171	N-acyltransferase activity
TPET_RS06510	COG0019	diaminopimelate decarboxylase activity
TPET_RS06515	COG1473	amidohydrolase
TPET_RS06530	COG1323	Belongs to the UPF0348 family
TPET_RS06535	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TPET_RS06535	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TPET_RS06540	COG2738	Putative neutral zinc metallopeptidase
TPET_RS06550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TPET_RS06555	COG1480	7TM receptor with intracellular HD hydrolase
TPET_RS06560	COG1702	phosphate starvation-inducible protein PhoH
TPET_RS06570	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
TPET_RS06575	COG0049	tRNA binding
TPET_RS06580	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TPET_RS06585	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TPET_RS06590	COG0051	transcription antitermination factor activity, RNA binding
TPET_RS06595	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TPET_RS06600	COG0088	Forms part of the polypeptide exit tunnel
TPET_RS06605	COG0089	rRNA binding
TPET_RS06610	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TPET_RS06615	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TPET_RS06620	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TPET_RS06625	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TPET_RS06630	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TPET_RS06635	COG0255	Belongs to the universal ribosomal protein uL29 family
TPET_RS06640	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TPET_RS06645	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TPET_RS06650	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TPET_RS06660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TPET_RS06665	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TPET_RS06670	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TPET_RS06675	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TPET_RS06680	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TPET_RS06685	COG1841	ribosomal large subunit assembly
TPET_RS06690	COG0200	Binds to the 23S rRNA
TPET_RS06695	COG0201	protein transport
TPET_RS06700	COG0563	adenylate kinase activity
TPET_RS06710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TPET_RS06715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
TPET_RS06720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TPET_RS06725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TPET_RS06730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TPET_RS06735	COG0202	RNA polymerase activity
TPET_RS06740	COG0203	ribosomal protein L17
TPET_RS06745	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TPET_RS06755	COG1307	EDD domain protein, DegV family
TPET_RS06765	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TPET_RS06770	COG0218	Necessary for normal cell division and for the maintenance of normal septation
TPET_RS06775	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
TPET_RS06780	COG2313	pseudouridylate synthase activity
TPET_RS06785	COG0230	Belongs to the bacterial ribosomal protein bL34 family
TPET_RS06790	COG0594	ribonuclease P activity
TPET_RS06795	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TPET_RS06800	COG0706	membrane insertase activity
TPET_RS06815	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TPET_RS06825	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TPET_RS06830	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
TPET_RS06835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TPET_RS06840	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TPET_RS06845	COG0358	DNA primase activity
TPET_RS06850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TPET_RS06855	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
TPET_RS06870	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TPET_RS06875	COG1160	GTP binding
TPET_RS06880	COG0539	negative regulation of cytoplasmic translation
TPET_RS06885	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TPET_RS06890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TPET_RS06895	COG1366	Belongs to the anti-sigma-factor antagonist family
TPET_RS06900	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TPET_RS06905	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TPET_RS06905	COG2050	protein possibly involved in aromatic compounds catabolism
TPET_RS06915	COG1543	Belongs to the glycosyl hydrolase 57 family
TPET_RS06920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TPET_RS06960	COG0840	transmembrane signaling receptor activity
TPET_RS06965	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TPET_RS06980	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
TPET_RS06995	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
TPET_RS07005	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TPET_RS07010	COG1213	nucleotidyl transferase
TPET_RS07010	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TPET_RS07015	COG0396	ATPase activity
TPET_RS07020	COG0719	Fe-S assembly protein
TPET_RS07030	COG0483	inositol monophosphate 1-phosphatase activity
TPET_RS07035	COG1621	beta-fructofuranosidase activity
TPET_RS07055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TPET_RS07060	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TPET_RS07065	COG0233	cytoplasmic translational termination
TPET_RS07070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TPET_RS07075	COG0575	Belongs to the CDS family
TPET_RS07080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TPET_RS07090	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
TPET_RS07095	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TPET_RS07105	COG0542	response to heat
TPET_RS07125	COG2264	protein methyltransferase activity
TPET_RS07130	COG0742	ribosomal rna small subunit methyltransferase
TPET_RS07135	COG0237	dephospho-CoA kinase activity
TPET_RS07145	COG0166	Belongs to the GPI family
TPET_RS07150	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TPET_RS07155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TPET_RS07175	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TPET_RS07180	COG1177	transmembrane transport
TPET_RS07185	COG1176	ABC-type spermidine putrescine transport system, permease component I
TPET_RS07190	COG3842	ATPase activity
TPET_RS07195	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
TPET_RS07205	COG0406	alpha-ribazole phosphatase activity
TPET_RS07215	COG0822	iron-sulfur transferase activity
TPET_RS07220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TPET_RS07230	COG0719	Fe-S assembly protein
TPET_RS07235	COG0396	ATPase activity
TPET_RS07250	COG1677	Flagellar hook-basal body complex protein FliE
TPET_RS07260	COG1815	bacterial-type flagellum-dependent cell motility
TPET_RS07265	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TPET_RS07275	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TPET_RS07280	COG0745	RESPONSE REGULATOR receiver
TPET_RS07285	COG3852	Histidine kinase
TPET_RS07310	COG0517	IMP dehydrogenase activity
TPET_RS07310	COG0516	GMP reductase activity
TPET_RS07325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TPET_RS07330	COG2267	carboxylic ester hydrolase activity
TPET_RS07335	COG0628	permease
TPET_RS07345	COG0516	GMP reductase activity
TPET_RS07345	COG0517	IMP dehydrogenase activity
TPET_RS07350	COG0612	Peptidase, M16
TPET_RS07355	COG1185	polyribonucleotide nucleotidyltransferase activity
TPET_RS07360	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TPET_RS07440	COG1132	(ABC) transporter
TPET_RS07445	COG4555	ABC transporter
TPET_RS07465	COG0641	radical SAM
TPET_RS07495	COG1598	PFAM Uncharacterised protein family UPF0150
TPET_RS07505	COG1132	(ABC) transporter
TPET_RS07510	COG1132	(ABC) transporter
TPET_RS07525	COG1598	PFAM Uncharacterised protein family UPF0150
TPET_RS07535	COG1598	PFAM Uncharacterised protein family UPF0150
TPET_RS07565	COG4555	ABC transporter
TPET_RS07585	COG0667	Aldo Keto reductase
TPET_RS07600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TPET_RS07615	COG0662	Cupin 2, conserved barrel domain protein
TPET_RS07620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TPET_RS07625	COG1486	melibiose metabolic process
TPET_RS07640	COG1193	negative regulation of DNA recombination
TPET_RS07650	COG3842	ATPase activity
TPET_RS07665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TPET_RS07670	COG0154	amidase activity
TPET_RS07675	COG2165	general secretion pathway protein
TPET_RS07680	COG0626	cystathionine gamma-synthase activity
TPET_RS07685	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TPET_RS07710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TPET_RS07725	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TPET_RS07730	COG0704	Plays a role in the regulation of phosphate uptake
TPET_RS07735	COG0745	RESPONSE REGULATOR receiver
TPET_RS07750	COG1132	(ABC) transporter
TPET_RS07755	COG0436	Aminotransferase
TPET_RS07760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TPET_RS07765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TPET_RS07765	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TPET_RS07780	COG0151	Belongs to the GarS family
TPET_RS07785	COG0138	bifunctional purine biosynthesis protein purh
TPET_RS07790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TPET_RS07795	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TPET_RS07800	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TPET_RS07805	COG0047	phosphoribosylformylglycinamidine synthase activity
TPET_RS07810	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TPET_RS07815	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TPET_RS07830	COG0012	GTP binding
TPET_RS07840	COG0210	DNA helicase
TPET_RS07865	COG3842	ATPase activity
TPET_RS07870	COG0383	alpha-mannosidase activity
TPET_RS07875	COG0438	transferase activity, transferring glycosyl groups
TPET_RS07880	COG0463	Glycosyl transferase, family 2
TPET_RS07895	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
TPET_RS07900	COG1940	carbohydrate kinase activity
TPET_RS07905	COG4166	transmembrane transport
TPET_RS07910	COG0601	transmembrane transport
TPET_RS07915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TPET_RS07920	COG0444	Belongs to the ABC transporter superfamily
TPET_RS07925	COG4608	Belongs to the ABC transporter superfamily
TPET_RS07930	COG1609	Transcriptional regulator
TPET_RS07935	COG2182	Extracellular solute-binding protein
TPET_RS07940	COG1175	transmembrane transport
TPET_RS07945	COG3833	ABC-type maltose transport systems, permease component
TPET_RS07955	COG1609	Transcriptional regulator
TPET_RS07965	COG0444	Belongs to the ABC transporter superfamily
TPET_RS07970	COG3250	beta-galactosidase activity
TPET_RS07975	COG3345	alpha-galactosidase
TPET_RS07980	COG1085	galactose-1-phosphate uridylyltransferase
TPET_RS07985	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TPET_RS07995	COG2199	diguanylate cyclase activity
TPET_RS08010	COG0628	permease
TPET_RS08020	COG1803	Methylglyoxal synthase
TPET_RS08030	COG0667	Aldo Keto reductase
TPET_RS08035	COG1196	nuclear chromosome segregation
TPET_RS08040	COG0494	nUDIX hydrolase
TPET_RS08050	COG1516	flagellar protein fliS
TPET_RS08055	COG0456	acetyltransferase
TPET_RS08060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TPET_RS08065	COG1151	hydroxylamine reductase activity
TPET_RS08080	COG1028	Short-chain dehydrogenase reductase Sdr
TPET_RS08085	COG0058	SHG alpha-glucan phosphorylase activity
TPET_RS08095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TPET_RS08100	COG1013	pyruvate-flavodoxin oxidoreductase activity
TPET_RS08110	COG2199	diguanylate cyclase activity
TPET_RS08115	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TPET_RS08120	COG2239	Acts as a magnesium transporter
TPET_RS08135	COG0010	Belongs to the arginase family
TPET_RS08150	COG1983	PspC domain protein
TPET_RS08155	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
TPET_RS08160	COG0363	glucosamine-6-phosphate deaminase activity
TPET_RS08165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TPET_RS08170	COG0444	Belongs to the ABC transporter superfamily
TPET_RS08175	COG4608	Belongs to the ABC transporter superfamily
TPET_RS08180	COG0747	negative chemotaxis
TPET_RS08185	COG0601	transmembrane transport
TPET_RS08200	COG0785	Cytochrome C biogenesis protein
TPET_RS08205	COG0517	IMP dehydrogenase activity
TPET_RS08205	COG0516	GMP reductase activity
TPET_RS08210	COG0410	ABC transporter
TPET_RS08245	COG0714	Associated with various cellular activities
TPET_RS08250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TPET_RS08255	COG0280	phosphate acetyltransferase
TPET_RS08260	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TPET_RS08295	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
TPET_RS08370	COG0651	ATP synthesis coupled electron transport
TPET_RS08385	COG0571	ribonuclease III activity
TPET_RS08390	COG0622	Phosphoesterase
TPET_RS08400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TPET_RS08410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TPET_RS08415	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TPET_RS08420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TPET_RS08425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TPET_RS08430	COG0018	arginyl-trna synthetase
TPET_RS08445	COG0124	histidyl-tRNA synthetase
TPET_RS08460	COG0569	domain protein
TPET_RS08475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TPET_RS08475	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TPET_RS08480	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TPET_RS08485	COG1371	PFAM Archease protein family (DUF101 UPF0211)
TPET_RS08490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TPET_RS08495	COG1366	Belongs to the anti-sigma-factor antagonist family
TPET_RS08500	COG0698	ribose 5-phosphate isomerase
TPET_RS08505	COG2264	protein methyltransferase activity
TPET_RS08515	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
TPET_RS08535	COG1070	Carbohydrate kinase
TPET_RS08540	COG0235	Class ii aldolase
TPET_RS08545	COG4952	isomerase
TPET_RS08555	COG1349	DNA-binding transcription factor activity
TPET_RS08560	COG1486	melibiose metabolic process
TPET_RS08565	COG0747	negative chemotaxis
TPET_RS08570	COG3401	FG-GAP repeat protein
TPET_RS08580	COG1175	transmembrane transport
TPET_RS08585	COG0395	ABC-type sugar transport system, permease component
TPET_RS08590	COG3408	Glycogen debranching enzyme
TPET_RS08595	COG0601	transmembrane transport
TPET_RS08600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TPET_RS08605	COG0444	Belongs to the ABC transporter superfamily
TPET_RS08610	COG4608	Belongs to the ABC transporter superfamily
TPET_RS08615	COG0747	negative chemotaxis
TPET_RS08625	COG3250	beta-galactosidase activity
TPET_RS08640	COG2359	stage V sporulation protein S
TPET_RS08650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TPET_RS08655	COG1324	tolerance protein
TPET_RS08665	COG1137	ATPase activity
TPET_RS08675	COG1555	photosystem II stabilization
TPET_RS08675	COG1596	polysaccharide export
TPET_RS08700	COG0850	regulation of cytokinetic process
TPET_RS08715	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
TPET_RS08720	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TPET_RS08725	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TPET_RS08730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TPET_RS08735	COG0131	Imidazoleglycerol-phosphate dehydratase
TPET_RS08740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TPET_RS08745	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TPET_RS08750	COG0107	imidazoleglycerol-phosphate synthase activity
TPET_RS08755	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TPET_RS08755	COG0140	phosphoribosyl-ATP diphosphatase activity
TPET_RS08760	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TPET_RS08790	COG1131	(ABC) transporter
TPET_RS08810	COG2814	Major facilitator Superfamily
TPET_RS08835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TPET_RS08885	COG0656	L-ascorbic acid biosynthetic process
TPET_RS08890	COG0667	Aldo Keto reductase
TPET_RS08895	COG2207	Transcriptional regulator
TPET_RS08910	COG0640	Transcriptional regulator
TPET_RS08925	COG0175	sulfate reduction
TPET_RS08950	COG3234	Protein of unknown function (DUF1175)
TPET_RS08960	COG2373	Large extracellular alpha-helical protein
TPET_RS08965	COG0425	Belongs to the sulfur carrier protein TusA family
TPET_RS08970	COG2391	methyltransferase activity
TPET_RS08990	COG0425	Belongs to the sulfur carrier protein TusA family
TPET_RS09000	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TPET_RS09005	COG0840	transmembrane signaling receptor activity
TPET_RS09065	COG2373	Large extracellular alpha-helical protein
TPET_RS09080	COG1606	tRNA processing
TPET_RS09085	COG1691	(AIR) carboxylase
TPET_RS09090	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
TPET_RS09100	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TPET_RS09105	COG1193	negative regulation of DNA recombination
TPET_RS09110	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
TPET_RS09115	COG1704	LemA family
TPET_RS09120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TPET_RS09130	COG1869	D-ribose catabolic process
TPET_RS09135	COG1129	ABC transporter
TPET_RS09140	COG1172	Belongs to the binding-protein-dependent transport system permease family
TPET_RS09145	COG1879	ABC-type sugar transport system periplasmic component
TPET_RS09170	COG0174	glutamine synthetase
TPET_RS09190	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TPET_RS09195	COG2226	methyltransferase
TPET_RS09205	COG0402	S-adenosylhomocysteine deaminase activity
TPET_RS09210	COG0517	IMP dehydrogenase activity
TPET_RS09210	COG0516	GMP reductase activity
TPET_RS09215	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TPET_RS09240	COG3864	Putative metallopeptidase domain