locus-tag	class	description
CELL2_RS00010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CELL2_RS00025	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CELL2_RS00025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CELL2_RS00030	COG0741	lytic transglycosylase activity
CELL2_RS00045	COG0840	transmembrane signaling receptor activity
CELL2_RS00060	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CELL2_RS00065	COG1392	Phosphate transport regulator
CELL2_RS00080	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CELL2_RS00090	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CELL2_RS00095	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CELL2_RS00100	COG1419	protein localization to endoplasmic reticulum
CELL2_RS00105	COG0455	bacterial-type flagellum organization
CELL2_RS00115	COG1776	CheC inhibitor of MCP methylation
CELL2_RS00125	COG1191	sigma factor activity
CELL2_RS00150	COG2359	stage V sporulation protein S
CELL2_RS00155	COG1085	galactose-1-phosphate uridylyltransferase
CELL2_RS00160	COG0297	glycogen (starch) synthase activity
CELL2_RS00170	COG1968	undecaprenyl-diphosphatase activity
CELL2_RS00175	COG2239	Acts as a magnesium transporter
CELL2_RS00180	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CELL2_RS00185	COG0750	zinc metalloprotease
CELL2_RS00190	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CELL2_RS00200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CELL2_RS00225	COG2873	o-acetylhomoserine
CELL2_RS00230	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CELL2_RS00235	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CELL2_RS00245	COG0674	pyruvate-flavodoxin oxidoreductase activity
CELL2_RS00245	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CELL2_RS00250	COG0148	phosphopyruvate hydratase activity
CELL2_RS00255	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CELL2_RS00265	COG1214	PFAM Peptidase M22, glycoprotease
CELL2_RS00270	COG0542	response to heat
CELL2_RS00275	COG0275	rRNA processing
CELL2_RS00290	COG0492	ferredoxin-NADP+ reductase activity
CELL2_RS00315	COG1234	tRNA 3'-trailer cleavage
CELL2_RS00330	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CELL2_RS00335	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CELL2_RS00340	COG1862	Preprotein translocase
CELL2_RS00355	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CELL2_RS00360	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CELL2_RS00365	COG1639	'signal transduction protein
CELL2_RS00370	COG5002	protein histidine kinase activity
CELL2_RS00400	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CELL2_RS00405	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CELL2_RS00410	COG0295	cytidine deaminase activity
CELL2_RS00415	COG4535	Mg2 and Co2 transporter CorC
CELL2_RS00420	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CELL2_RS00430	COG4565	transcriptional regulatory protein
CELL2_RS00445	COG0772	Belongs to the SEDS family
CELL2_RS00455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CELL2_RS00460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CELL2_RS00465	COG0849	cell division
CELL2_RS00475	COG0187	DNA topoisomerase II activity
CELL2_RS00485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CELL2_RS00490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELL2_RS00505	COG3842	ATPase activity
CELL2_RS00525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CELL2_RS00525	COG0072	phenylalanine-tRNA ligase activity
CELL2_RS00530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CELL2_RS00540	COG1979	alcohol dehydrogenase
CELL2_RS00550	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
CELL2_RS00575	COG0534	Mate efflux family protein
CELL2_RS00585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CELL2_RS00590	COG0395	ABC-type sugar transport system, permease component
CELL2_RS00605	COG1472	Belongs to the glycosyl hydrolase 3 family
CELL2_RS00610	COG1846	Transcriptional regulator
CELL2_RS00610	COG1940	carbohydrate kinase activity
CELL2_RS00615	COG0450	alkyl hydroperoxide reductase
CELL2_RS00625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CELL2_RS00630	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CELL2_RS00635	COG0504	CTP synthase activity
CELL2_RS00645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CELL2_RS00650	COG2070	2-Nitropropane dioxygenase
CELL2_RS00655	COG1268	BioY protein
CELL2_RS00660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CELL2_RS00665	COG2045	Belongs to the ComB family
CELL2_RS00690	COG1131	(ABC) transporter
CELL2_RS00695	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CELL2_RS00700	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CELL2_RS00705	COG1992	Thiamine-phosphate synthase
CELL2_RS00705	COG0351	phosphomethylpyrimidine kinase
CELL2_RS00715	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CELL2_RS00720	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
CELL2_RS00775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CELL2_RS00790	COG1774	PSP1 C-terminal conserved region
CELL2_RS00805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CELL2_RS00810	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CELL2_RS00815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CELL2_RS00825	COG1131	(ABC) transporter
CELL2_RS00835	COG0393	Putative heavy-metal-binding
CELL2_RS00840	COG0052	Belongs to the universal ribosomal protein uS2 family
CELL2_RS00875	COG0426	domain, Protein
CELL2_RS00880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CELL2_RS00885	COG2226	methyltransferase
CELL2_RS00890	COG1486	melibiose metabolic process
CELL2_RS00900	COG0572	uridine kinase
CELL2_RS00915	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CELL2_RS00920	COG0793	Belongs to the peptidase S41A family
CELL2_RS00935	COG0438	transferase activity, transferring glycosyl groups
CELL2_RS00945	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CELL2_RS00960	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CELL2_RS00960	COG2199	diguanylate cyclase activity
CELL2_RS00975	COG1482	cell wall glycoprotein biosynthetic process
CELL2_RS01000	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CELL2_RS01010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CELL2_RS01020	COG0312	modulator of DNA gyrase
CELL2_RS01025	COG0312	modulator of DNA gyrase
CELL2_RS01045	COG0557	exoribonuclease II activity
CELL2_RS01050	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CELL2_RS01060	COG0215	cysteine-tRNA ligase activity
CELL2_RS01070	COG0511	ligase activity, forming carbon-carbon bonds
CELL2_RS01070	COG5016	pyruvate
CELL2_RS01080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CELL2_RS01085	COG3620	sequence-specific DNA binding
CELL2_RS01085	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CELL2_RS01085	COG0617	tRNA 3'-terminal CCA addition
CELL2_RS01115	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CELL2_RS01120	COG0095	Lipoate-protein ligase
CELL2_RS01125	COG0357	Ribosomal RNA small subunit methyltransferase G
CELL2_RS01135	COG1136	(ABC) transporter
CELL2_RS01140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CELL2_RS01145	COG1546	Belongs to the CinA family
CELL2_RS01145	COG1058	Belongs to the CinA family
CELL2_RS01150	COG2198	Histidine kinase
CELL2_RS01150	COG0643	Histidine kinase
CELL2_RS01155	COG0835	chemotaxis
CELL2_RS01160	COG2201	protein-glutamate methylesterase activity
CELL2_RS01170	COG1338	Plays a role in the flagellum-specific transport system
CELL2_RS01185	COG0740	serine-type endopeptidase activity
CELL2_RS01190	COG0544	peptidyl-prolyl cis-trans isomerase activity
CELL2_RS01200	COG0736	holo-[acyl-carrier-protein] synthase activity
CELL2_RS01215	COG0149	triose-phosphate isomerase activity
CELL2_RS01215	COG0126	phosphoglycerate kinase activity
CELL2_RS01220	COG0126	phosphoglycerate kinase activity
CELL2_RS01225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CELL2_RS01230	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CELL2_RS01235	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CELL2_RS01285	COG1360	Flagellar Motor Protein
CELL2_RS01295	COG1582	Flagellar protein (FlbD)
CELL2_RS01300	COG1749	Flagellar hook protein flgE
CELL2_RS01335	COG0084	hydrolase, TatD family'
CELL2_RS01340	COG1045	serine acetyltransferase
CELL2_RS01345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CELL2_RS01360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CELL2_RS01370	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
CELL2_RS01375	COG1773	rubredoxin
CELL2_RS01380	COG2033	superoxide reductase activity
CELL2_RS01385	COG1592	Rubrerythrin
CELL2_RS01390	COG1476	TRANSCRIPTIONal
CELL2_RS01395	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CELL2_RS01400	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CELL2_RS01405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELL2_RS01415	COG0561	phosphatase activity
CELL2_RS01430	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CELL2_RS01440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CELL2_RS01500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CELL2_RS01505	COG0438	transferase activity, transferring glycosyl groups
CELL2_RS01545	COG1216	Glycosyl transferase, family 2
CELL2_RS01545	COG1442	glycosyl transferase family 8
CELL2_RS01565	COG0438	transferase activity, transferring glycosyl groups
CELL2_RS01565	COG0297	glycogen (starch) synthase activity
CELL2_RS01570	COG1216	Glycosyl transferase, family 2
CELL2_RS01635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CELL2_RS01645	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CELL2_RS01650	COG0629	single-stranded DNA binding
CELL2_RS01655	COG0360	Binds together with S18 to 16S ribosomal RNA
CELL2_RS01680	COG0395	ABC-type sugar transport system, permease component
CELL2_RS01685	COG1175	transmembrane transport
CELL2_RS01695	COG2252	PERMEase
CELL2_RS01700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CELL2_RS01705	COG0765	amino acid transport
CELL2_RS01715	COG0768	penicillin binding
CELL2_RS01730	COG1077	Cell shape determining protein MreB Mrl
CELL2_RS01735	COG1227	inorganic diphosphatase activity
CELL2_RS01735	COG0517	IMP dehydrogenase activity
CELL2_RS01740	COG0697	spore germination
CELL2_RS01745	COG0673	inositol 2-dehydrogenase activity
CELL2_RS01770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CELL2_RS01775	COG0037	tRNA processing
CELL2_RS01785	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CELL2_RS01790	COG0456	acetyltransferase
CELL2_RS01795	COG2176	DNA-directed DNA polymerase activity
CELL2_RS01800	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CELL2_RS01805	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CELL2_RS01810	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CELL2_RS01815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CELL2_RS01820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CELL2_RS01825	COG0552	protein localization to endoplasmic reticulum
CELL2_RS01840	COG1959	2 iron, 2 sulfur cluster binding
CELL2_RS01850	COG1489	DNA binding
CELL2_RS01875	COG0598	Magnesium transport protein CorA
CELL2_RS01890	COG0505	Belongs to the CarA family
CELL2_RS01900	COG0473	3-isopropylmalate dehydrogenase activity
CELL2_RS01905	COG0066	3-isopropylmalate dehydratase activity
CELL2_RS01910	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CELL2_RS01920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CELL2_RS01935	COG0440	acetolactate synthase activity
CELL2_RS01940	COG0028	Belongs to the TPP enzyme family
CELL2_RS01945	COG0527	aspartate kinase activity
CELL2_RS01950	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CELL2_RS01955	COG0083	homoserine kinase activity
CELL2_RS01960	COG1131	(ABC) transporter
CELL2_RS01975	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CELL2_RS01975	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CELL2_RS01995	COG4717	serine-type aminopeptidase activity
CELL2_RS02010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CELL2_RS02015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_RS02020	COG0601	transmembrane transport
CELL2_RS02025	COG0747	negative chemotaxis
CELL2_RS02030	COG4608	Belongs to the ABC transporter superfamily
CELL2_RS02035	COG2608	mercury ion transmembrane transporter activity
CELL2_RS02045	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CELL2_RS02050	COG1923	regulation of RNA biosynthetic process
CELL2_RS02055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CELL2_RS02080	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CELL2_RS02085	COG0482	sulfurtransferase activity
CELL2_RS02110	COG1242	4 iron, 4 sulfur cluster binding
CELL2_RS02115	COG0442	prolyl-tRNA aminoacylation
CELL2_RS02120	COG0606	chelatase, subunit chli
CELL2_RS02130	COG1573	uracil-dna glycosylase
CELL2_RS02145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CELL2_RS02145	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CELL2_RS02150	COG0459	protein refolding
CELL2_RS02155	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CELL2_RS02160	COG0601	transmembrane transport
CELL2_RS02165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_RS02175	COG4608	Belongs to the ABC transporter superfamily
CELL2_RS02185	COG0444	Belongs to the ABC transporter superfamily
CELL2_RS02200	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CELL2_RS02205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CELL2_RS02215	COG0180	Tryptophanyl-tRNA synthetase
CELL2_RS02225	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CELL2_RS02230	COG1595	DNA-templated transcription, initiation
CELL2_RS02235	COG2890	protein-(glutamine-N5) methyltransferase activity
CELL2_RS02240	COG2151	metal-sulfur cluster biosynthetic enzyme
CELL2_RS02250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CELL2_RS02255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CELL2_RS02260	COG1116	anion transmembrane transporter activity
CELL2_RS02290	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CELL2_RS02295	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CELL2_RS02300	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CELL2_RS02305	COG1196	nuclear chromosome segregation
CELL2_RS02320	COG1335	isochorismatase
CELL2_RS02355	COG0745	RESPONSE REGULATOR receiver
CELL2_RS02375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CELL2_RS02380	COG0564	pseudouridine synthase activity
CELL2_RS02385	COG0587	DNA-directed DNA polymerase activity
CELL2_RS02395	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CELL2_RS02400	COG0085	RNA polymerase activity
CELL2_RS02405	COG0222	ribosome binding
CELL2_RS02410	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CELL2_RS02415	COG0081	regulation of translation
CELL2_RS02420	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CELL2_RS02425	COG0250	Participates in transcription elongation, termination and antitermination
CELL2_RS02430	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CELL2_RS02440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CELL2_RS02465	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CELL2_RS02470	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CELL2_RS02480	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CELL2_RS02485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CELL2_RS02490	COG1027	Aspartate ammonia-lyase
CELL2_RS02495	COG1070	Carbohydrate kinase
CELL2_RS02515	COG1802	Transcriptional regulator
CELL2_RS02520	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CELL2_RS02545	COG1172	Belongs to the binding-protein-dependent transport system permease family
CELL2_RS02555	COG1082	Xylose isomerase domain protein TIM barrel
CELL2_RS02560	COG3842	ATPase activity
CELL2_RS02565	COG3833	ABC-type maltose transport systems, permease component
CELL2_RS02570	COG1175	transmembrane transport
CELL2_RS02580	COG1082	Xylose isomerase domain protein TIM barrel
CELL2_RS02590	COG0673	inositol 2-dehydrogenase activity
CELL2_RS02595	COG1402	creatininase
CELL2_RS02600	COG1063	alcohol dehydrogenase
CELL2_RS02605	COG1940	carbohydrate kinase activity
CELL2_RS02615	COG0739	heme binding
CELL2_RS02620	COG2201	protein-glutamate methylesterase activity
CELL2_RS02635	COG1013	pyruvate-flavodoxin oxidoreductase activity
CELL2_RS02645	COG0347	Belongs to the P(II) protein family
CELL2_RS02650	COG0004	ammonium transporteR
CELL2_RS02655	COG1435	thymidine kinase activity
CELL2_RS02660	COG3850	Histidine kinase
CELL2_RS02660	COG5002	protein histidine kinase activity
CELL2_RS02675	COG0067	glutamate synthase
CELL2_RS02685	COG0493	'glutamate synthase
CELL2_RS02685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CELL2_RS02705	COG0438	transferase activity, transferring glycosyl groups
CELL2_RS02715	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CELL2_RS02735	COG1194	a g-specific adenine glycosylase
CELL2_RS02740	COG0778	Nitroreductase
CELL2_RS02755	COG0778	Nitroreductase
CELL2_RS02770	COG1131	(ABC) transporter
CELL2_RS02775	COG0730	response to heat
CELL2_RS02780	COG4869	propanediol catabolic process
CELL2_RS02785	COG0071	Belongs to the small heat shock protein (HSP20) family
CELL2_RS02790	COG0443	Heat shock 70 kDa protein
CELL2_RS02795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CELL2_RS02800	COG1438	arginine binding
CELL2_RS02805	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
CELL2_RS02820	COG0840	transmembrane signaling receptor activity
CELL2_RS02830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CELL2_RS02835	COG1362	aminopeptidase activity
CELL2_RS02865	COG3956	TIGRFAM MazG family protein
CELL2_RS02880	COG0438	transferase activity, transferring glycosyl groups
CELL2_RS02885	COG1597	lipid kinase activity
CELL2_RS02900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CELL2_RS02915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CELL2_RS02920	COG1136	(ABC) transporter
CELL2_RS02925	COG0577	efflux transmembrane transporter activity
CELL2_RS02925	COG1136	(ABC) transporter
CELL2_RS02935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CELL2_RS02940	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CELL2_RS02940	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CELL2_RS02950	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CELL2_RS02955	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CELL2_RS02965	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CELL2_RS02990	COG1032	radical SAM domain protein
CELL2_RS02995	COG1073	alpha beta
CELL2_RS03005	COG0543	2 iron, 2 sulfur cluster binding
CELL2_RS03010	COG0167	dihydroorotate dehydrogenase activity
CELL2_RS03015	COG0284	orotidine-5'-phosphate decarboxylase activity
CELL2_RS03020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CELL2_RS03025	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CELL2_RS03045	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CELL2_RS03050	COG1737	Transcriptional regulator
CELL2_RS03055	COG1028	Short-chain dehydrogenase reductase Sdr
CELL2_RS03060	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CELL2_RS03070	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CELL2_RS03105	COG0667	Aldo Keto reductase
CELL2_RS03125	COG0747	negative chemotaxis
CELL2_RS03130	COG1501	Belongs to the glycosyl hydrolase 31 family
CELL2_RS03145	COG1830	Aldolase
CELL2_RS03150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CELL2_RS03155	COG1063	alcohol dehydrogenase
CELL2_RS03160	COG1028	Short-chain dehydrogenase reductase Sdr
CELL2_RS03165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CELL2_RS03185	COG0066	3-isopropylmalate dehydratase activity
CELL2_RS03190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CELL2_RS03195	COG0372	Belongs to the citrate synthase family
CELL2_RS03200	COG0205	6-phosphofructokinase activity
CELL2_RS03205	COG1132	(ABC) transporter
CELL2_RS03210	COG1132	(ABC) transporter
CELL2_RS03220	COG0371	Dehydrogenase
CELL2_RS03230	COG0235	Class ii aldolase
CELL2_RS03250	COG0395	ABC-type sugar transport system, permease component
CELL2_RS03255	COG1175	transmembrane transport
CELL2_RS03275	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CELL2_RS03280	COG0191	fructose-bisphosphate aldolase activity
CELL2_RS03285	COG0574	Belongs to the PEP-utilizing enzyme family
CELL2_RS03285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CELL2_RS03295	COG0646	methionine synthase
CELL2_RS03295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CELL2_RS03305	COG1410	methionine synthase
CELL2_RS03305	COG0646	methionine synthase
CELL2_RS03310	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CELL2_RS03315	COG0776	regulation of translation
CELL2_RS03320	COG0322	excinuclease ABC activity
CELL2_RS03325	COG1187	pseudouridine synthase activity
CELL2_RS03335	COG0592	DNA-directed DNA polymerase activity
CELL2_RS03340	COG0306	phosphate transporter
CELL2_RS03355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CELL2_RS03360	COG3481	metal-dependent phosphohydrolase, HD sub domain
CELL2_RS03375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CELL2_RS03380	COG0792	nuclease activity
CELL2_RS03385	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CELL2_RS03390	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CELL2_RS03395	COG0758	DNA mediated transformation
CELL2_RS03400	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
CELL2_RS03400	COG2878	Part of a membrane complex involved in electron transport
CELL2_RS03410	COG4660	Part of a membrane complex involved in electron transport
CELL2_RS03420	COG4658	electron transport chain
CELL2_RS03425	COG4656	Part of a membrane complex involved in electron transport
CELL2_RS03450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CELL2_RS03460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CELL2_RS03470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CELL2_RS03475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CELL2_RS03480	COG0772	Belongs to the SEDS family
CELL2_RS03485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CELL2_RS03490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CELL2_RS03520	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CELL2_RS03525	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CELL2_RS03525	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CELL2_RS03535	COG1122	ATPase activity
CELL2_RS03540	COG1766	The M ring may be actively involved in energy transduction
CELL2_RS03545	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CELL2_RS03555	COG1157	protein secretion by the type III secretion system
CELL2_RS03565	COG0752	glycyl-tRNA synthetase alpha subunit
CELL2_RS03570	COG0251	oxidation-reduction process
CELL2_RS03575	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CELL2_RS03585	COG0509	glycine decarboxylation via glycine cleavage system
CELL2_RS03590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CELL2_RS03600	COG0205	6-phosphofructokinase activity
CELL2_RS03605	COG0469	pyruvate kinase activity
CELL2_RS03610	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CELL2_RS03615	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CELL2_RS03620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CELL2_RS03645	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CELL2_RS03650	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CELL2_RS03655	COG0542	response to heat
CELL2_RS03660	COG0037	tRNA processing
CELL2_RS03685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CELL2_RS03690	COG0390	transport system, permease component
CELL2_RS03715	COG2359	stage V sporulation protein S
CELL2_RS03720	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CELL2_RS03725	COG4139	cobalamin transport
CELL2_RS03730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CELL2_RS03770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELL2_RS03815	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CELL2_RS03820	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CELL2_RS03830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CELL2_RS03835	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CELL2_RS03845	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CELL2_RS03850	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CELL2_RS03860	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CELL2_RS03865	COG0495	leucyl-tRNA aminoacylation
CELL2_RS03870	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CELL2_RS03875	COG0285	dihydrofolate synthase activity
CELL2_RS03880	COG0632	four-way junction helicase activity
CELL2_RS03910	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CELL2_RS03915	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CELL2_RS03930	COG1785	Belongs to the alkaline phosphatase family
CELL2_RS03955	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CELL2_RS03960	COG0416	fatty acid biosynthetic process
CELL2_RS03965	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CELL2_RS03970	COG0799	negative regulation of ribosome biogenesis
CELL2_RS03975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CELL2_RS03980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CELL2_RS04000	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CELL2_RS04005	COG0512	Glutamine amidotransferase of anthranilate synthase
CELL2_RS04005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CELL2_RS04010	COG0134	indole-3-glycerol-phosphate synthase activity
CELL2_RS04015	COG0135	phosphoribosylanthranilate isomerase activity
CELL2_RS04020	COG0133	tryptophan synthase activity
CELL2_RS04025	COG0159	tryptophan synthase activity
CELL2_RS04030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CELL2_RS04040	COG0492	ferredoxin-NADP+ reductase activity
CELL2_RS04045	COG1335	isochorismatase
CELL2_RS04050	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CELL2_RS04080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CELL2_RS04085	COG1121	(ABC) transporter
CELL2_RS04100	COG1509	lysine 2,3-aminomutase activity
CELL2_RS04105	COG0778	Nitroreductase
CELL2_RS04125	COG1070	Carbohydrate kinase
CELL2_RS04130	COG1129	ABC transporter
CELL2_RS04145	COG1172	Belongs to the binding-protein-dependent transport system permease family
CELL2_RS04160	COG1940	carbohydrate kinase activity
CELL2_RS04170	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CELL2_RS04185	COG1079	Belongs to the binding-protein-dependent transport system permease family
CELL2_RS04190	COG4603	Belongs to the binding-protein-dependent transport system permease family
CELL2_RS04195	COG3845	ABC transporter
CELL2_RS04200	COG1744	ABC transporter substrate-binding protein PnrA-like
CELL2_RS04210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CELL2_RS04225	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CELL2_RS04230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CELL2_RS04230	COG3116	cell division
CELL2_RS04235	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
CELL2_RS04240	COG1459	type II secretion system
CELL2_RS04280	COG0728	peptidoglycan biosynthetic process
CELL2_RS04300	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CELL2_RS04305	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CELL2_RS04310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CELL2_RS04315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CELL2_RS04320	COG1120	ATPase activity
CELL2_RS04325	COG3458	cephalosporin-C deacetylase activity
CELL2_RS04330	COG1472	Belongs to the glycosyl hydrolase 3 family
CELL2_RS04335	COG4608	Belongs to the ABC transporter superfamily
CELL2_RS04340	COG0444	Belongs to the ABC transporter superfamily
CELL2_RS04345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_RS04350	COG0601	transmembrane transport
CELL2_RS04365	COG1312	Catalyzes the dehydration of D-mannonate
CELL2_RS04370	COG0246	Mannitol dehydrogenase
CELL2_RS04380	COG0800	Aldolase
CELL2_RS04385	COG1414	Transcriptional regulator
CELL2_RS04405	COG3693	PFAM glycoside hydrolase, family 10
CELL2_RS04410	COG0601	transmembrane transport
CELL2_RS04415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_RS04420	COG0444	Belongs to the ABC transporter superfamily
CELL2_RS04425	COG4608	Belongs to the ABC transporter superfamily
CELL2_RS04430	COG0747	negative chemotaxis
CELL2_RS04435	COG3661	Belongs to the glycosyl hydrolase 67 family
CELL2_RS04455	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CELL2_RS04455	COG1918	ferrous iron import across plasma membrane
CELL2_RS04465	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
CELL2_RS04490	COG1132	(ABC) transporter
CELL2_RS04495	COG0006	proline dipeptidase activity
CELL2_RS04500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CELL2_RS04500	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CELL2_RS04505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CELL2_RS04515	COG0720	synthase
CELL2_RS04520	COG2199	diguanylate cyclase activity
CELL2_RS04520	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CELL2_RS04555	COG0601	transmembrane transport
CELL2_RS04565	COG0444	Belongs to the ABC transporter superfamily
CELL2_RS04570	COG4608	Belongs to the ABC transporter superfamily
CELL2_RS04595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CELL2_RS04600	COG1993	acr, cog1993
CELL2_RS04610	COG1028	Short-chain dehydrogenase reductase Sdr
CELL2_RS04615	COG1013	pyruvate-flavodoxin oxidoreductase activity
CELL2_RS04620	COG0674	pyruvate-flavodoxin oxidoreductase activity
CELL2_RS04625	COG1144	Oxidoreductase
CELL2_RS04630	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CELL2_RS04665	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CELL2_RS04675	COG4948	Mandelate Racemase Muconate Lactonizing
CELL2_RS04685	COG0737	Belongs to the 5'-nucleotidase family
CELL2_RS04695	COG0622	Phosphoesterase
CELL2_RS04700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CELL2_RS04705	COG1278	Cold shock
CELL2_RS04715	COG0432	Pfam Uncharacterised protein family UPF0047
CELL2_RS04725	COG2894	cell division
CELL2_RS04730	COG1067	ATP-dependent peptidase activity
CELL2_RS04735	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CELL2_RS04740	COG0039	L-malate dehydrogenase activity
CELL2_RS04770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CELL2_RS04775	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CELL2_RS04780	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CELL2_RS04790	COG1418	mRNA catabolic process
CELL2_RS04815	COG1175	transmembrane transport
CELL2_RS04820	COG0395	ABC-type sugar transport system, permease component
CELL2_RS04845	COG3459	Glycosyltransferase 36 associated
CELL2_RS04850	COG2723	6-phospho-beta-galactosidase activity
CELL2_RS04855	COG1653	transport
CELL2_RS04870	COG1940	carbohydrate kinase activity
CELL2_RS04880	COG1523	belongs to the glycosyl hydrolase 13 family
CELL2_RS04885	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CELL2_RS04905	COG0366	Alpha amylase catalytic
CELL2_RS04910	COG2182	Extracellular solute-binding protein
CELL2_RS04915	COG1175	transmembrane transport
CELL2_RS04920	COG3833	ABC-type maltose transport systems, permease component
CELL2_RS04925	COG0366	Alpha amylase catalytic
CELL2_RS04940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_RS04945	COG4608	Belongs to the ABC transporter superfamily
CELL2_RS04955	COG1486	melibiose metabolic process
CELL2_RS04960	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
CELL2_RS04975	COG3706	GGDEF domain
CELL2_RS04980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CELL2_RS04980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CELL2_RS04985	COG0307	riboflavin synthase, alpha
CELL2_RS04990	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CELL2_RS04990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CELL2_RS05010	COG0330	HflC and HflK could
CELL2_RS05015	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
CELL2_RS05030	COG2059	Chromate
CELL2_RS05035	COG0525	valine-tRNA ligase activity
CELL2_RS05060	COG1353	crispr-associated protein
CELL2_RS05070	COG1337	RAMP superfamily
CELL2_RS05100	COG0484	heat shock protein binding
CELL2_RS05135	COG1518	maintenance of DNA repeat elements
CELL2_RS05140	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CELL2_RS05180	COG0640	Transcriptional regulator
CELL2_RS05195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CELL2_RS05200	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CELL2_RS05205	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CELL2_RS05215	COG0165	Argininosuccinate lyase
CELL2_RS05235	COG0195	Participates in both transcription termination and antitermination
CELL2_RS05240	COG0735	belongs to the Fur family
CELL2_RS05260	COG1461	Dihydroxyacetone kinase
CELL2_RS05275	COG1722	exodeoxyribonuclease VII activity
CELL2_RS05290	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CELL2_RS05305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CELL2_RS05310	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CELL2_RS05315	COG0556	nucleotide-excision repair
CELL2_RS05350	COG3426	butyrate kinase activity
CELL2_RS05355	COG0280	phosphate acetyltransferase
CELL2_RS05360	COG3426	butyrate kinase activity
CELL2_RS05370	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CELL2_RS05375	COG0667	Aldo Keto reductase
CELL2_RS05380	COG0647	UMP catabolic process
CELL2_RS05385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CELL2_RS05390	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CELL2_RS05405	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CELL2_RS05410	COG0305	Participates in initiation and elongation during chromosome replication
CELL2_RS05420	COG0704	Plays a role in the regulation of phosphate uptake
CELL2_RS05435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CELL2_RS05440	COG2255	four-way junction helicase activity
CELL2_RS05465	COG1394	ATPase activity, coupled to movement of substances
CELL2_RS05470	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
CELL2_RS05475	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
CELL2_RS05495	COG1269	ATP hydrolysis coupled proton transport
CELL2_RS05515	COG1028	Short-chain dehydrogenase reductase Sdr
CELL2_RS05545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CELL2_RS05550	COG1162	GTPase activity
CELL2_RS05570	COG1739	Uncharacterized protein family UPF0029
CELL2_RS05590	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CELL2_RS05600	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CELL2_RS05610	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CELL2_RS05620	COG1368	sulfuric ester hydrolase activity
CELL2_RS05640	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CELL2_RS05645	COG0436	Aminotransferase
CELL2_RS05650	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CELL2_RS05665	COG0301	tRNA thio-modification
CELL2_RS05685	COG2052	Domain of unknown function (DUF370)
CELL2_RS05690	COG0194	GDP metabolic process
CELL2_RS05695	COG1758	RNA polymerase activity
CELL2_RS05700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CELL2_RS05705	COG1376	ErfK ybiS ycfS ynhG family protein
CELL2_RS05710	COG1185	polyribonucleotide nucleotidyltransferase activity
CELL2_RS05720	COG1278	Cold shock
CELL2_RS05725	COG3437	response regulator, receiver
CELL2_RS05770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CELL2_RS05800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CELL2_RS05810	COG2813	Specifically methylates the guanine in position
CELL2_RS05815	COG1122	ATPase activity
CELL2_RS05820	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CELL2_RS05825	COG0242	peptide deformylase activity
CELL2_RS05840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CELL2_RS05855	COG0745	RESPONSE REGULATOR receiver
CELL2_RS05860	COG5002	protein histidine kinase activity
CELL2_RS05875	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CELL2_RS05890	COG1713	HD superfamily hydrolase involved in NAD metabolism
CELL2_RS05905	COG0157	Belongs to the NadC ModD family
CELL2_RS05920	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
CELL2_RS05920	COG0540	Belongs to the ATCase OTCase family
CELL2_RS05925	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CELL2_RS05935	COG0543	2 iron, 2 sulfur cluster binding
CELL2_RS05940	COG4555	ABC transporter
CELL2_RS05955	COG0420	3'-5' exonuclease activity
CELL2_RS05965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CELL2_RS05970	COG0802	atpase or kinase
CELL2_RS05985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CELL2_RS05990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CELL2_RS06015	COG0481	GTPase activity
CELL2_RS06025	COG0584	glycerophosphoryl diester phosphodiesterase
CELL2_RS06035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CELL2_RS06035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CELL2_RS06040	COG1406	Chemotaxis phosphatase CheX
CELL2_RS06055	COG0356	it plays a direct role in the translocation of protons across the membrane
CELL2_RS06060	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CELL2_RS06065	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CELL2_RS06070	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CELL2_RS06075	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CELL2_RS06080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CELL2_RS06085	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CELL2_RS06090	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CELL2_RS06100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CELL2_RS06105	COG1530	ribonuclease E activity
CELL2_RS06115	COG0528	UMP kinase activity
CELL2_RS06120	COG0477	Major facilitator Superfamily
CELL2_RS06125	COG1827	regulation of RNA biosynthetic process
CELL2_RS06130	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CELL2_RS06145	COG1595	DNA-templated transcription, initiation
CELL2_RS06155	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CELL2_RS06160	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CELL2_RS06170	COG0489	protein tyrosine kinase activity
CELL2_RS06180	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CELL2_RS06185	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CELL2_RS06230	COG2379	hydroxypyruvate reductase
CELL2_RS06235	COG1040	competence protein
CELL2_RS06260	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CELL2_RS06265	COG0653	protein targeting
CELL2_RS06275	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CELL2_RS06285	COG0101	tRNA pseudouridine synthase activity
CELL2_RS06295	COG0681	Belongs to the peptidase S26 family
CELL2_RS06300	COG0335	large ribosomal subunit rRNA binding
CELL2_RS06305	COG4752	Belongs to the RNA methyltransferase TrmD family
CELL2_RS06310	COG0336	Belongs to the RNA methyltransferase TrmD family
CELL2_RS06315	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CELL2_RS06320	COG1837	Belongs to the UPF0109 family
CELL2_RS06325	COG0228	four-way junction DNA binding
CELL2_RS06330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CELL2_RS06335	COG1254	Belongs to the acylphosphatase family
CELL2_RS06360	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CELL2_RS06370	COG2003	Belongs to the UPF0758 family
CELL2_RS06390	COG1477	protein flavinylation
CELL2_RS06400	COG2078	PFAM AMMECR1 domain protein
CELL2_RS06405	COG3872	metal-dependent enzyme
CELL2_RS06410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CELL2_RS06415	COG1086	Polysaccharide biosynthesis protein
CELL2_RS06420	COG1078	dGTPase activity
CELL2_RS06425	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CELL2_RS06425	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CELL2_RS06445	COG4786	Flagellar basal body rod
CELL2_RS06460	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CELL2_RS06465	COG1706	bacterial-type flagellum-dependent cell motility
CELL2_RS06475	COG1032	radical SAM domain protein
CELL2_RS06500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CELL2_RS06510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CELL2_RS06530	COG0019	diaminopimelate decarboxylase activity
CELL2_RS06535	COG1473	amidohydrolase
CELL2_RS06550	COG1323	Belongs to the UPF0348 family
CELL2_RS06555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CELL2_RS06555	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CELL2_RS06560	COG2738	Putative neutral zinc metallopeptidase
CELL2_RS06575	COG1480	7TM receptor with intracellular HD hydrolase
CELL2_RS06580	COG1702	phosphate starvation-inducible protein PhoH
CELL2_RS06590	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CELL2_RS06595	COG0049	tRNA binding
CELL2_RS06600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CELL2_RS06605	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CELL2_RS06610	COG0051	transcription antitermination factor activity, RNA binding
CELL2_RS06615	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CELL2_RS06620	COG0088	Forms part of the polypeptide exit tunnel
CELL2_RS06625	COG0089	rRNA binding
CELL2_RS06630	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CELL2_RS06635	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CELL2_RS06640	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CELL2_RS06645	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CELL2_RS06650	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CELL2_RS06655	COG0255	Belongs to the universal ribosomal protein uL29 family
CELL2_RS06660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CELL2_RS06665	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CELL2_RS06670	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CELL2_RS06680	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CELL2_RS06685	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CELL2_RS06690	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CELL2_RS06695	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CELL2_RS06700	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CELL2_RS06705	COG1841	ribosomal large subunit assembly
CELL2_RS06710	COG0200	Binds to the 23S rRNA
CELL2_RS06715	COG0201	protein transport
CELL2_RS06720	COG0563	adenylate kinase activity
CELL2_RS06730	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CELL2_RS06735	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CELL2_RS06740	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CELL2_RS06745	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CELL2_RS06750	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CELL2_RS06755	COG0202	RNA polymerase activity
CELL2_RS06760	COG0203	ribosomal protein L17
CELL2_RS06765	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CELL2_RS06775	COG1307	EDD domain protein, DegV family
CELL2_RS06785	COG3437	response regulator, receiver
CELL2_RS06790	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CELL2_RS06795	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CELL2_RS06805	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CELL2_RS06815	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CELL2_RS06820	COG0706	membrane insertase activity
CELL2_RS06845	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CELL2_RS06850	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CELL2_RS06855	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CELL2_RS06865	COG0358	DNA primase activity
CELL2_RS06870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CELL2_RS06875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CELL2_RS06890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CELL2_RS06905	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CELL2_RS06915	COG1366	Belongs to the anti-sigma-factor antagonist family
CELL2_RS06925	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CELL2_RS06925	COG2050	protein possibly involved in aromatic compounds catabolism
CELL2_RS06935	COG1543	Belongs to the glycosyl hydrolase 57 family
CELL2_RS06980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CELL2_RS06990	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CELL2_RS07005	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CELL2_RS07020	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CELL2_RS07035	COG1213	nucleotidyl transferase
CELL2_RS07035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CELL2_RS07045	COG0719	Fe-S assembly protein
CELL2_RS07055	COG0483	inositol monophosphate 1-phosphatase activity
CELL2_RS07060	COG1621	beta-fructofuranosidase activity
CELL2_RS07080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CELL2_RS07085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CELL2_RS07100	COG0575	Belongs to the CDS family
CELL2_RS07115	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CELL2_RS07120	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CELL2_RS07155	COG2264	protein methyltransferase activity
CELL2_RS07160	COG0742	ribosomal rna small subunit methyltransferase
CELL2_RS07165	COG0237	dephospho-CoA kinase activity
CELL2_RS07175	COG0166	Belongs to the GPI family
CELL2_RS07180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CELL2_RS07185	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CELL2_RS07205	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CELL2_RS07210	COG1177	transmembrane transport
CELL2_RS07215	COG1176	ABC-type spermidine putrescine transport system, permease component I
CELL2_RS07220	COG3842	ATPase activity
CELL2_RS07225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CELL2_RS07235	COG0406	alpha-ribazole phosphatase activity
CELL2_RS07245	COG0822	iron-sulfur transferase activity
CELL2_RS07250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CELL2_RS07255	COG0719	Fe-S assembly protein
CELL2_RS07255	COG1372	Participates in initiation and elongation during chromosome replication
CELL2_RS07260	COG0719	Fe-S assembly protein
CELL2_RS07265	COG0396	ATPase activity
CELL2_RS07280	COG1677	Flagellar hook-basal body complex protein FliE
CELL2_RS07290	COG1815	bacterial-type flagellum-dependent cell motility
CELL2_RS07295	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CELL2_RS07305	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CELL2_RS07310	COG0745	RESPONSE REGULATOR receiver
CELL2_RS07340	COG0516	GMP reductase activity
CELL2_RS07340	COG0517	IMP dehydrogenase activity
CELL2_RS07355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CELL2_RS07360	COG2267	carboxylic ester hydrolase activity
CELL2_RS07365	COG0628	permease
CELL2_RS07375	COG0516	GMP reductase activity
CELL2_RS07375	COG0517	IMP dehydrogenase activity
CELL2_RS07380	COG0612	Peptidase, M16
CELL2_RS07390	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CELL2_RS07470	COG1598	PFAM Uncharacterised protein family UPF0150
CELL2_RS07480	COG1598	PFAM Uncharacterised protein family UPF0150
CELL2_RS07510	COG4555	ABC transporter
CELL2_RS07530	COG0667	Aldo Keto reductase
CELL2_RS07540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CELL2_RS07555	COG0662	Cupin 2, conserved barrel domain protein
CELL2_RS07560	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CELL2_RS07580	COG1193	negative regulation of DNA recombination
CELL2_RS07590	COG3842	ATPase activity
CELL2_RS07610	COG0154	amidase activity
CELL2_RS07620	COG0626	cystathionine gamma-synthase activity
CELL2_RS07625	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CELL2_RS07650	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CELL2_RS07665	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CELL2_RS07670	COG0704	Plays a role in the regulation of phosphate uptake
CELL2_RS07675	COG0745	RESPONSE REGULATOR receiver
CELL2_RS07690	COG1132	(ABC) transporter
CELL2_RS07695	COG0436	Aminotransferase
CELL2_RS07700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CELL2_RS07705	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CELL2_RS07705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CELL2_RS07720	COG0151	Belongs to the GarS family
CELL2_RS07725	COG0138	bifunctional purine biosynthesis protein purh
CELL2_RS07730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CELL2_RS07735	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CELL2_RS07740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CELL2_RS07745	COG0047	phosphoribosylformylglycinamidine synthase activity
CELL2_RS07750	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CELL2_RS07780	COG0210	DNA helicase
CELL2_RS07805	COG3842	ATPase activity
CELL2_RS07810	COG0383	alpha-mannosidase activity
CELL2_RS07815	COG0438	transferase activity, transferring glycosyl groups
CELL2_RS07820	COG0463	Glycosyl transferase, family 2
CELL2_RS07835	COG0747	negative chemotaxis
CELL2_RS07840	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
CELL2_RS07845	COG1940	carbohydrate kinase activity
CELL2_RS07850	COG4166	transmembrane transport
CELL2_RS07860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CELL2_RS07865	COG0444	Belongs to the ABC transporter superfamily
CELL2_RS07870	COG4608	Belongs to the ABC transporter superfamily
CELL2_RS07875	COG1609	Transcriptional regulator
CELL2_RS07885	COG0649	NAD binding
CELL2_RS07890	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CELL2_RS07890	COG0649	NAD binding
CELL2_RS07895	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CELL2_RS07905	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CELL2_RS07910	COG0651	ATP synthesis coupled electron transport
CELL2_RS07920	COG2111	Na H antiporter
CELL2_RS07920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CELL2_RS07935	COG2212	antiporter activity
CELL2_RS07940	COG1863	multisubunit Na H antiporter MnhE subunit
CELL2_RS07955	COG1175	transmembrane transport
CELL2_RS07960	COG0395	ABC-type sugar transport system, permease component
CELL2_RS07970	COG0444	Belongs to the ABC transporter superfamily
CELL2_RS07975	COG3250	beta-galactosidase activity
CELL2_RS07980	COG3345	alpha-galactosidase
CELL2_RS07985	COG1085	galactose-1-phosphate uridylyltransferase
CELL2_RS07990	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CELL2_RS08000	COG2199	diguanylate cyclase activity
CELL2_RS08015	COG0628	permease
CELL2_RS08025	COG1803	Methylglyoxal synthase
CELL2_RS08035	COG0667	Aldo Keto reductase
CELL2_RS08040	COG1196	nuclear chromosome segregation
CELL2_RS08045	COG0494	nUDIX hydrolase
CELL2_RS08055	COG1516	flagellar protein fliS
CELL2_RS08060	COG0456	acetyltransferase
CELL2_RS08065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CELL2_RS08070	COG1151	hydroxylamine reductase activity
CELL2_RS08085	COG1028	Short-chain dehydrogenase reductase Sdr
CELL2_RS08090	COG0058	SHG alpha-glucan phosphorylase activity
CELL2_RS08100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CELL2_RS08105	COG1013	pyruvate-flavodoxin oxidoreductase activity
CELL2_RS08115	COG2199	diguanylate cyclase activity
CELL2_RS08120	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CELL2_RS08125	COG2239	Acts as a magnesium transporter
CELL2_RS08140	COG0010	Belongs to the arginase family
CELL2_RS08155	COG1983	PspC domain protein
CELL2_RS08160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CELL2_RS08165	COG0363	glucosamine-6-phosphate deaminase activity
CELL2_RS08175	COG0444	Belongs to the ABC transporter superfamily
CELL2_RS08180	COG4608	Belongs to the ABC transporter superfamily
CELL2_RS08185	COG0747	negative chemotaxis
CELL2_RS08190	COG0601	transmembrane transport
CELL2_RS08205	COG0785	Cytochrome C biogenesis protein
CELL2_RS08250	COG0714	Associated with various cellular activities
CELL2_RS08255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CELL2_RS08260	COG0280	phosphate acetyltransferase
CELL2_RS08265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CELL2_RS08295	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CELL2_RS08305	COG1175	transmembrane transport
CELL2_RS08310	COG1653	transport
CELL2_RS08385	COG0651	ATP synthesis coupled electron transport
CELL2_RS08405	COG0622	Phosphoesterase
CELL2_RS08425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CELL2_RS08430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CELL2_RS08435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CELL2_RS08440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CELL2_RS08465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CELL2_RS08475	COG0569	domain protein
CELL2_RS08490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CELL2_RS08490	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CELL2_RS08495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CELL2_RS08510	COG1366	Belongs to the anti-sigma-factor antagonist family
CELL2_RS08515	COG0698	ribose 5-phosphate isomerase
CELL2_RS08550	COG1070	Carbohydrate kinase
CELL2_RS08560	COG4952	isomerase
CELL2_RS08570	COG1349	DNA-binding transcription factor activity
CELL2_RS08575	COG1486	melibiose metabolic process
CELL2_RS08590	COG3250	beta-galactosidase activity
CELL2_RS08605	COG2359	stage V sporulation protein S
CELL2_RS08615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CELL2_RS08620	COG1324	tolerance protein
CELL2_RS08630	COG1137	ATPase activity
CELL2_RS08640	COG1596	polysaccharide export
CELL2_RS08640	COG1555	photosystem II stabilization
CELL2_RS08685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CELL2_RS08690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CELL2_RS08700	COG0131	Imidazoleglycerol-phosphate dehydratase
CELL2_RS08705	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CELL2_RS08710	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CELL2_RS08715	COG0107	imidazoleglycerol-phosphate synthase activity
CELL2_RS08720	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CELL2_RS08720	COG0140	phosphoribosyl-ATP diphosphatase activity
CELL2_RS08725	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CELL2_RS08730	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CELL2_RS08730	COG0662	Cupin 2, conserved barrel domain protein
CELL2_RS08755	COG1131	(ABC) transporter
CELL2_RS08785	COG2814	Major facilitator Superfamily
CELL2_RS08810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CELL2_RS08845	COG0656	L-ascorbic acid biosynthetic process
CELL2_RS08855	COG0667	Aldo Keto reductase
CELL2_RS08860	COG2207	Transcriptional regulator
CELL2_RS08875	COG1691	(AIR) carboxylase
CELL2_RS08890	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CELL2_RS08895	COG1193	negative regulation of DNA recombination
CELL2_RS08900	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CELL2_RS08905	COG1704	LemA family
CELL2_RS08910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CELL2_RS08920	COG1869	D-ribose catabolic process
CELL2_RS08925	COG1129	ABC transporter
CELL2_RS08935	COG1879	ABC-type sugar transport system periplasmic component
CELL2_RS08970	COG0174	glutamine synthetase
CELL2_RS08990	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CELL2_RS09005	COG0402	S-adenosylhomocysteine deaminase activity
CELL2_RS09010	COG0517	IMP dehydrogenase activity
CELL2_RS09010	COG0516	GMP reductase activity
CELL2_RS09015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CELL2_RS09035	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CELL2_RS09040	COG3864	Putative metallopeptidase domain
CELL2_RS09050	COG1141	Ferredoxin