locus-tag	class	description
TCCBUS3UF1_RS00005	COG0445	tRNA wobble uridine modification
TCCBUS3UF1_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TCCBUS3UF1_RS00015	COG0592	DNA-directed DNA polymerase activity
TCCBUS3UF1_RS00020	COG0148	phosphopyruvate hydratase activity
TCCBUS3UF1_RS00025	COG0469	pyruvate kinase activity
TCCBUS3UF1_RS00030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TCCBUS3UF1_RS00040	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TCCBUS3UF1_RS00045	COG1937	Protein conserved in bacteria
TCCBUS3UF1_RS00055	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TCCBUS3UF1_RS00055	COG0674	pyruvate-flavodoxin oxidoreductase activity
TCCBUS3UF1_RS00060	COG1013	pyruvate-flavodoxin oxidoreductase activity
TCCBUS3UF1_RS00070	COG0315	cyclic pyranopterin monophosphate synthase activity
TCCBUS3UF1_RS00085	COG2010	Cytochrome c
TCCBUS3UF1_RS00090	COG0535	radical SAM domain protein
TCCBUS3UF1_RS00105	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TCCBUS3UF1_RS00120	COG1842	Phage shock protein A
TCCBUS3UF1_RS00130	COG1131	(ABC) transporter
TCCBUS3UF1_RS00135	COG0842	Transport permease protein
TCCBUS3UF1_RS00155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TCCBUS3UF1_RS00160	COG1047	Peptidyl-prolyl cis-trans
TCCBUS3UF1_RS00165	COG1278	Cold shock
TCCBUS3UF1_RS00170	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TCCBUS3UF1_RS00190	COG2860	membrane
TCCBUS3UF1_RS00195	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TCCBUS3UF1_RS00220	COG0459	protein refolding
TCCBUS3UF1_RS00225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TCCBUS3UF1_RS00235	COG0714	Associated with various cellular activities
TCCBUS3UF1_RS00245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TCCBUS3UF1_RS00255	COG0166	Belongs to the GPI family
TCCBUS3UF1_RS00260	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
TCCBUS3UF1_RS00265	COG1612	heme a metabolic process
TCCBUS3UF1_RS00265	COG0109	protoheme IX farnesyltransferase activity
TCCBUS3UF1_RS00270	COG2010	Cytochrome c
TCCBUS3UF1_RS00270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TCCBUS3UF1_RS00275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TCCBUS3UF1_RS00275	COG1845	cytochrome c oxidase, subunit III
TCCBUS3UF1_RS00310	COG0582	viral genome integration into host DNA
TCCBUS3UF1_RS00330	COG1111	helicase
TCCBUS3UF1_RS00330	COG1205	dead DEAH box helicase
TCCBUS3UF1_RS00345	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TCCBUS3UF1_RS00380	COG0410	ABC transporter
TCCBUS3UF1_RS00395	COG0559	Belongs to the binding-protein-dependent transport system permease family
TCCBUS3UF1_RS00405	COG1028	Short-chain dehydrogenase reductase Sdr
TCCBUS3UF1_RS00410	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TCCBUS3UF1_RS00460	COG1309	transcriptional regulator
TCCBUS3UF1_RS00465	COG1960	acyl-CoA dehydrogenase activity
TCCBUS3UF1_RS00475	COG1028	Short-chain dehydrogenase reductase Sdr
TCCBUS3UF1_RS00480	COG2030	dehydratase
TCCBUS3UF1_RS00480	COG1012	belongs to the aldehyde dehydrogenase family
TCCBUS3UF1_RS00490	COG0318	PFAM AMP-dependent synthetase and ligase
TCCBUS3UF1_RS00495	COG1028	Short-chain dehydrogenase reductase Sdr
TCCBUS3UF1_RS00515	COG0318	PFAM AMP-dependent synthetase and ligase
TCCBUS3UF1_RS00535	COG0800	Aldolase
TCCBUS3UF1_RS00540	COG1414	Transcriptional regulator
TCCBUS3UF1_RS00545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TCCBUS3UF1_RS00555	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TCCBUS3UF1_RS00560	COG1028	Short-chain dehydrogenase reductase Sdr
TCCBUS3UF1_RS00565	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
TCCBUS3UF1_RS00575	COG1028	Short-chain dehydrogenase reductase Sdr
TCCBUS3UF1_RS00620	COG0393	Putative heavy-metal-binding
TCCBUS3UF1_RS00640	COG1598	PFAM Uncharacterised protein family UPF0150
TCCBUS3UF1_RS00655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TCCBUS3UF1_RS00665	COG1475	DNA binding
TCCBUS3UF1_RS00670	COG1192	Involved in chromosome partitioning
TCCBUS3UF1_RS00690	COG1404	Belongs to the peptidase S8 family
TCCBUS3UF1_RS00700	COG1492	cobalamin metabolic process
TCCBUS3UF1_RS00725	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TCCBUS3UF1_RS00740	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TCCBUS3UF1_RS00745	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
TCCBUS3UF1_RS00860	COG0395	ABC-type sugar transport system, permease component
TCCBUS3UF1_RS00865	COG1175	transmembrane transport
TCCBUS3UF1_RS00885	COG3842	ATPase activity
TCCBUS3UF1_RS00895	COG1840	ABC-type Fe3 transport system, periplasmic component
TCCBUS3UF1_RS00920	COG1349	DNA-binding transcription factor activity
TCCBUS3UF1_RS00925	COG0434	BtpA family
TCCBUS3UF1_RS00930	COG1070	Carbohydrate kinase
TCCBUS3UF1_RS00940	COG0395	ABC-type sugar transport system, permease component
TCCBUS3UF1_RS00950	COG1175	transmembrane transport
TCCBUS3UF1_RS00970	COG4558	Periplasmic binding protein
TCCBUS3UF1_RS00975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TCCBUS3UF1_RS00980	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TCCBUS3UF1_RS00995	COG4607	ABC-type enterochelin transport system periplasmic component
TCCBUS3UF1_RS01000	COG1607	acyl-coa hydrolase
TCCBUS3UF1_RS01005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TCCBUS3UF1_RS01015	COG1372	Participates in initiation and elongation during chromosome replication
TCCBUS3UF1_RS01015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TCCBUS3UF1_RS01030	COG2239	Acts as a magnesium transporter
TCCBUS3UF1_RS01035	COG0811	peptide transport
TCCBUS3UF1_RS01060	COG1797	cobyrinic acid a,c-diamide synthase activity
TCCBUS3UF1_RS01110	COG1518	maintenance of DNA repeat elements
TCCBUS3UF1_RS01140	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TCCBUS3UF1_RS01165	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
TCCBUS3UF1_RS01175	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TCCBUS3UF1_RS01185	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TCCBUS3UF1_RS01190	COG2814	Major facilitator Superfamily
TCCBUS3UF1_RS01195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TCCBUS3UF1_RS01200	COG0581	inorganic phosphate transmembrane transporter activity
TCCBUS3UF1_RS01205	COG0573	inorganic phosphate transmembrane transporter activity
TCCBUS3UF1_RS01210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TCCBUS3UF1_RS01215	COG0482	sulfurtransferase activity
TCCBUS3UF1_RS01225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TCCBUS3UF1_RS01230	COG0735	belongs to the Fur family
TCCBUS3UF1_RS01245	COG0583	DNA-binding transcription factor activity
TCCBUS3UF1_RS01255	COG0508	dehydrogenase complex catalyzes the overall conversion of
TCCBUS3UF1_RS01260	COG0181	hydroxymethylbilane synthase activity
TCCBUS3UF1_RS01270	COG0285	dihydrofolate synthase activity
TCCBUS3UF1_RS01285	COG0436	Aminotransferase
TCCBUS3UF1_RS01290	COG0521	Mo-molybdopterin cofactor biosynthetic process
TCCBUS3UF1_RS01305	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TCCBUS3UF1_RS01310	COG0154	amidase activity
TCCBUS3UF1_RS01315	COG0301	tRNA thio-modification
TCCBUS3UF1_RS01320	COG0243	molybdopterin cofactor binding
TCCBUS3UF1_RS01325	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TCCBUS3UF1_RS01335	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TCCBUS3UF1_RS01365	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TCCBUS3UF1_RS01375	COG0105	UTP biosynthetic process
TCCBUS3UF1_RS01380	COG0631	protein serine/threonine phosphatase activity
TCCBUS3UF1_RS01395	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
TCCBUS3UF1_RS01400	COG3956	TIGRFAM MazG family protein
TCCBUS3UF1_RS01425	COG1131	(ABC) transporter
TCCBUS3UF1_RS01450	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TCCBUS3UF1_RS01470	COG1902	pentaerythritol trinitrate reductase activity
TCCBUS3UF1_RS01490	COG1489	DNA binding
TCCBUS3UF1_RS01510	COG1115	amino acid carrier protein
TCCBUS3UF1_RS01530	COG0442	prolyl-tRNA aminoacylation
TCCBUS3UF1_RS01540	COG0539	negative regulation of cytoplasmic translation
TCCBUS3UF1_RS01545	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TCCBUS3UF1_RS01550	COG0723	plastoquinol--plastocyanin reductase activity
TCCBUS3UF1_RS01585	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TCCBUS3UF1_RS01620	COG0470	DNA polymerase III
TCCBUS3UF1_RS01625	COG1774	PSP1 C-terminal conserved region
TCCBUS3UF1_RS01640	COG1079	Belongs to the binding-protein-dependent transport system permease family
TCCBUS3UF1_RS01645	COG4603	Belongs to the binding-protein-dependent transport system permease family
TCCBUS3UF1_RS01650	COG2226	methyltransferase
TCCBUS3UF1_RS01670	COG1193	negative regulation of DNA recombination
TCCBUS3UF1_RS01680	COG0366	Alpha amylase catalytic
TCCBUS3UF1_RS01705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TCCBUS3UF1_RS01715	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TCCBUS3UF1_RS01720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TCCBUS3UF1_RS01730	COG1166	arginine decarboxylase activity
TCCBUS3UF1_RS01745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TCCBUS3UF1_RS01755	COG0316	Belongs to the HesB IscA family
TCCBUS3UF1_RS01760	COG4166	transmembrane transport
TCCBUS3UF1_RS01765	COG0601	transmembrane transport
TCCBUS3UF1_RS01770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TCCBUS3UF1_RS01775	COG0101	tRNA pseudouridine synthase activity
TCCBUS3UF1_RS01800	COG1764	response to oxidative stress
TCCBUS3UF1_RS01810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TCCBUS3UF1_RS01815	COG2897	thiosulfate sulfurtransferase activity
TCCBUS3UF1_RS01820	COG0071	Belongs to the small heat shock protein (HSP20) family
TCCBUS3UF1_RS01825	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
TCCBUS3UF1_RS01830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TCCBUS3UF1_RS01845	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TCCBUS3UF1_RS01850	COG0792	nuclease activity
TCCBUS3UF1_RS01865	COG1028	Short-chain dehydrogenase reductase Sdr
TCCBUS3UF1_RS01870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TCCBUS3UF1_RS01880	COG1187	pseudouridine synthase activity
TCCBUS3UF1_RS01890	COG1459	type II secretion system
TCCBUS3UF1_RS01895	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
TCCBUS3UF1_RS01920	COG2165	general secretion pathway protein
TCCBUS3UF1_RS01925	COG2165	general secretion pathway protein
TCCBUS3UF1_RS01935	COG2165	general secretion pathway protein
TCCBUS3UF1_RS01940	COG2720	vancomycin resistance protein
TCCBUS3UF1_RS01950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TCCBUS3UF1_RS01955	COG0427	acetyl-CoA hydrolase
TCCBUS3UF1_RS01975	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TCCBUS3UF1_RS01980	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TCCBUS3UF1_RS01985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TCCBUS3UF1_RS01990	COG0805	protein transport
TCCBUS3UF1_RS01995	COG1605	Chorismate mutase
TCCBUS3UF1_RS01995	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TCCBUS3UF1_RS02050	COG1063	alcohol dehydrogenase
TCCBUS3UF1_RS02065	COG1643	Atp-dependent helicase
TCCBUS3UF1_RS02070	COG0187	DNA topoisomerase II activity
TCCBUS3UF1_RS02085	COG0156	8-amino-7-oxononanoate synthase activity
TCCBUS3UF1_RS02100	COG1802	Transcriptional regulator
TCCBUS3UF1_RS02105	COG0506	proline dehydrogenase activity
TCCBUS3UF1_RS02110	COG1012	belongs to the aldehyde dehydrogenase family
TCCBUS3UF1_RS02115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TCCBUS3UF1_RS02120	COG0512	Glutamine amidotransferase of anthranilate synthase
TCCBUS3UF1_RS02130	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TCCBUS3UF1_RS02145	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
TCCBUS3UF1_RS02150	COG1187	pseudouridine synthase activity
TCCBUS3UF1_RS02155	COG1024	Enoyl-CoA hydratase
TCCBUS3UF1_RS02160	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TCCBUS3UF1_RS02165	COG0686	Belongs to the AlaDH PNT family
TCCBUS3UF1_RS02175	COG1461	Dihydroxyacetone kinase
TCCBUS3UF1_RS02190	COG4591	ABC-type transport system involved in lipoprotein release permease component
TCCBUS3UF1_RS02205	COG0049	tRNA binding
TCCBUS3UF1_RS02220	COG0051	transcription antitermination factor activity, RNA binding
TCCBUS3UF1_RS02230	COG0088	Forms part of the polypeptide exit tunnel
TCCBUS3UF1_RS02235	COG0089	rRNA binding
TCCBUS3UF1_RS02240	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TCCBUS3UF1_RS02245	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TCCBUS3UF1_RS02255	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TCCBUS3UF1_RS02260	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TCCBUS3UF1_RS02265	COG0255	Belongs to the universal ribosomal protein uL29 family
TCCBUS3UF1_RS02300	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TCCBUS3UF1_RS02325	COG0201	protein transport
TCCBUS3UF1_RS02330	COG0563	adenylate kinase activity
TCCBUS3UF1_RS02340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TCCBUS3UF1_RS02350	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TCCBUS3UF1_RS02355	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TCCBUS3UF1_RS02360	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TCCBUS3UF1_RS02370	COG0203	ribosomal protein L17
TCCBUS3UF1_RS02400	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TCCBUS3UF1_RS02410	COG0142	geranyltranstransferase activity
TCCBUS3UF1_RS02415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TCCBUS3UF1_RS02420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TCCBUS3UF1_RS02450	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
TCCBUS3UF1_RS02460	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
TCCBUS3UF1_RS02465	COG2385	sporulation resulting in formation of a cellular spore
TCCBUS3UF1_RS02480	COG0194	GDP metabolic process
TCCBUS3UF1_RS02490	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TCCBUS3UF1_RS02495	COG1438	arginine binding
TCCBUS3UF1_RS02500	COG2095	MarC family integral membrane protein
TCCBUS3UF1_RS02510	COG0497	DNA recombination
TCCBUS3UF1_RS02515	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TCCBUS3UF1_RS02530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TCCBUS3UF1_RS02540	COG0047	phosphoribosylformylglycinamidine synthase activity
TCCBUS3UF1_RS02550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TCCBUS3UF1_RS02555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TCCBUS3UF1_RS02585	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TCCBUS3UF1_RS02615	COG3850	Histidine kinase
TCCBUS3UF1_RS02615	COG5002	protein histidine kinase activity
TCCBUS3UF1_RS02625	COG1272	protein, Hemolysin III
TCCBUS3UF1_RS02630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TCCBUS3UF1_RS02630	COG0574	Belongs to the PEP-utilizing enzyme family
TCCBUS3UF1_RS02635	COG0714	Associated with various cellular activities
TCCBUS3UF1_RS02640	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TCCBUS3UF1_RS02645	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
TCCBUS3UF1_RS02650	COG0483	inositol monophosphate 1-phosphatase activity
TCCBUS3UF1_RS02655	COG0135	phosphoribosylanthranilate isomerase activity
TCCBUS3UF1_RS02665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TCCBUS3UF1_RS02670	COG0537	adenosine 5'-monophosphoramidase activity
TCCBUS3UF1_RS02685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TCCBUS3UF1_RS02695	COG1011	Hydrolase
TCCBUS3UF1_RS02700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TCCBUS3UF1_RS02725	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TCCBUS3UF1_RS02730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TCCBUS3UF1_RS02735	COG4946	Tricorn protease homolog
TCCBUS3UF1_RS02735	COG0823	Involved in the tonB-independent uptake of proteins
TCCBUS3UF1_RS02735	COG1506	peptidase
TCCBUS3UF1_RS02760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TCCBUS3UF1_RS02765	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TCCBUS3UF1_RS02770	COG0113	porphobilinogen synthase activity
TCCBUS3UF1_RS02785	COG0631	protein serine/threonine phosphatase activity
TCCBUS3UF1_RS02790	COG0515	serine threonine protein kinase
TCCBUS3UF1_RS02790	COG2815	serine threonine protein kinase
TCCBUS3UF1_RS02825	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TCCBUS3UF1_RS02830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TCCBUS3UF1_RS02835	COG0504	CTP synthase activity
TCCBUS3UF1_RS02855	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
TCCBUS3UF1_RS02860	COG2010	Cytochrome c
TCCBUS3UF1_RS02880	COG3258	Cytochrome c
TCCBUS3UF1_RS02885	COG2010	Cytochrome c
TCCBUS3UF1_RS02890	COG0737	Belongs to the 5'-nucleotidase family
TCCBUS3UF1_RS02895	COG2010	Cytochrome c
TCCBUS3UF1_RS02900	COG3258	Cytochrome c
TCCBUS3UF1_RS02915	COG0446	pyridine nucleotide-disulphide oxidoreductase
TCCBUS3UF1_RS02920	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TCCBUS3UF1_RS02930	COG0785	Cytochrome C biogenesis protein
TCCBUS3UF1_RS02935	COG4133	protoheme IX ABC transporter activity
TCCBUS3UF1_RS02945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TCCBUS3UF1_RS02950	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
TCCBUS3UF1_RS02955	COG1138	Cytochrome C-type biogenesis protein
TCCBUS3UF1_RS02960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TCCBUS3UF1_RS02965	COG3088	subunit of a heme lyase
TCCBUS3UF1_RS02970	COG2010	Cytochrome c
TCCBUS3UF1_RS02985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TCCBUS3UF1_RS02995	COG0268	Binds directly to 16S ribosomal RNA
TCCBUS3UF1_RS03010	COG0083	homoserine kinase activity
TCCBUS3UF1_RS03020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TCCBUS3UF1_RS03020	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TCCBUS3UF1_RS03025	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TCCBUS3UF1_RS03035	COG1160	GTP binding
TCCBUS3UF1_RS03050	COG0736	holo-[acyl-carrier-protein] synthase activity
TCCBUS3UF1_RS03055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TCCBUS3UF1_RS03055	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
TCCBUS3UF1_RS03060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TCCBUS3UF1_RS03065	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TCCBUS3UF1_RS03070	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TCCBUS3UF1_RS03075	COG1450	Type ii and iii secretion system protein
TCCBUS3UF1_RS03100	COG0473	3-isopropylmalate dehydrogenase activity
TCCBUS3UF1_RS03130	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
TCCBUS3UF1_RS03140	COG0860	N-Acetylmuramoyl-L-alanine amidase
TCCBUS3UF1_RS03145	COG2815	serine threonine protein kinase
TCCBUS3UF1_RS03145	COG0515	serine threonine protein kinase
TCCBUS3UF1_RS03150	COG1752	Esterase of the alpha-beta hydrolase superfamily
TCCBUS3UF1_RS03160	COG1556	Lactate utilization protein
TCCBUS3UF1_RS03165	COG1139	Iron-sulfur cluster binding protein
TCCBUS3UF1_RS03170	COG0247	lactate metabolic process
TCCBUS3UF1_RS03175	COG2205	protein histidine kinase activity
TCCBUS3UF1_RS03195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TCCBUS3UF1_RS03200	COG1324	tolerance protein
TCCBUS3UF1_RS03205	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TCCBUS3UF1_RS03210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TCCBUS3UF1_RS03215	COG0739	heme binding
TCCBUS3UF1_RS03220	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TCCBUS3UF1_RS03225	COG2197	response regulator
TCCBUS3UF1_RS03240	COG1132	(ABC) transporter
TCCBUS3UF1_RS03245	COG1132	(ABC) transporter
TCCBUS3UF1_RS03250	COG0285	dihydrofolate synthase activity
TCCBUS3UF1_RS03260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TCCBUS3UF1_RS03265	COG0601	transmembrane transport
TCCBUS3UF1_RS03270	COG0747	negative chemotaxis
TCCBUS3UF1_RS03290	COG0559	Belongs to the binding-protein-dependent transport system permease family
TCCBUS3UF1_RS03300	COG0174	glutamine synthetase
TCCBUS3UF1_RS03305	COG0737	Belongs to the 5'-nucleotidase family
TCCBUS3UF1_RS03325	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TCCBUS3UF1_RS03330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TCCBUS3UF1_RS03335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
TCCBUS3UF1_RS03340	COG0788	formyltetrahydrofolate deformylase activity
TCCBUS3UF1_RS03355	COG2358	TRAP transporter, solute receptor (TAXI family
TCCBUS3UF1_RS03380	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TCCBUS3UF1_RS03385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TCCBUS3UF1_RS03390	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TCCBUS3UF1_RS03455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TCCBUS3UF1_RS03460	COG0328	RNA-DNA hybrid ribonuclease activity
TCCBUS3UF1_RS03470	COG4274	PFAM GYD family protein
TCCBUS3UF1_RS03475	COG0519	Catalyzes the synthesis of GMP from XMP
TCCBUS3UF1_RS03475	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TCCBUS3UF1_RS03480	COG1854	S-ribosylhomocysteine lyase activity
TCCBUS3UF1_RS03485	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TCCBUS3UF1_RS03490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TCCBUS3UF1_RS03495	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TCCBUS3UF1_RS03500	COG0193	aminoacyl-tRNA hydrolase activity
TCCBUS3UF1_RS03505	COG1181	Belongs to the D-alanine--D-alanine ligase family
TCCBUS3UF1_RS03515	COG2211	Major facilitator Superfamily
TCCBUS3UF1_RS03525	COG1085	galactose-1-phosphate uridylyltransferase
TCCBUS3UF1_RS03535	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
TCCBUS3UF1_RS03555	COG2255	four-way junction helicase activity
TCCBUS3UF1_RS03560	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TCCBUS3UF1_RS03570	COG5002	protein histidine kinase activity
TCCBUS3UF1_RS03580	COG0745	RESPONSE REGULATOR receiver
TCCBUS3UF1_RS03590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TCCBUS3UF1_RS03595	COG0232	Belongs to the dGTPase family. Type 2 subfamily
TCCBUS3UF1_RS03600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TCCBUS3UF1_RS03605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TCCBUS3UF1_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
TCCBUS3UF1_RS03615	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TCCBUS3UF1_RS03620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TCCBUS3UF1_RS03625	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TCCBUS3UF1_RS03645	COG1007	ATP synthesis coupled electron transport
TCCBUS3UF1_RS03650	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCCBUS3UF1_RS03655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TCCBUS3UF1_RS03660	COG0713	ATP synthesis coupled electron transport
TCCBUS3UF1_RS03665	COG0839	Belongs to the complex I subunit 6 family
TCCBUS3UF1_RS03670	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCCBUS3UF1_RS03675	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TCCBUS3UF1_RS03680	COG1034	ATP synthesis coupled electron transport
TCCBUS3UF1_RS03685	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TCCBUS3UF1_RS03690	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
TCCBUS3UF1_RS03695	COG0649	NAD binding
TCCBUS3UF1_RS03700	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCCBUS3UF1_RS03705	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCCBUS3UF1_RS03710	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TCCBUS3UF1_RS03715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TCCBUS3UF1_RS03725	COG4712	double-strand break repair protein
TCCBUS3UF1_RS03760	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TCCBUS3UF1_RS03765	COG0131	Imidazoleglycerol-phosphate dehydratase
TCCBUS3UF1_RS03770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TCCBUS3UF1_RS03775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TCCBUS3UF1_RS03780	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TCCBUS3UF1_RS03810	COG0861	Integral membrane protein TerC family
TCCBUS3UF1_RS03815	COG2151	metal-sulfur cluster biosynthetic enzyme
TCCBUS3UF1_RS03820	COG0281	malic enzyme
TCCBUS3UF1_RS03835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TCCBUS3UF1_RS03840	COG0509	glycine decarboxylation via glycine cleavage system
TCCBUS3UF1_RS03845	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TCCBUS3UF1_RS03850	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TCCBUS3UF1_RS03855	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TCCBUS3UF1_RS03870	COG0243	molybdopterin cofactor binding
TCCBUS3UF1_RS03880	COG2197	response regulator
TCCBUS3UF1_RS03890	COG0196	riboflavin kinase activity
TCCBUS3UF1_RS03895	COG0494	nUDIX hydrolase
TCCBUS3UF1_RS03905	COG1574	metal-dependent hydrolase with the TIM-barrel fold
TCCBUS3UF1_RS03925	COG2813	Specifically methylates the guanine in position
TCCBUS3UF1_RS03930	COG0527	aspartate kinase activity
TCCBUS3UF1_RS03955	COG1205	dead DEAH box helicase
TCCBUS3UF1_RS03955	COG1111	helicase
TCCBUS3UF1_RS03970	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TCCBUS3UF1_RS03975	COG0009	L-threonylcarbamoyladenylate synthase
TCCBUS3UF1_RS03980	COG1459	type II secretion system
TCCBUS3UF1_RS03990	COG0277	FAD linked oxidase domain protein
TCCBUS3UF1_RS04000	COG0287	Prephenate dehydrogenase
TCCBUS3UF1_RS04005	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TCCBUS3UF1_RS04010	COG2514	catechol 2,3-dioxygenase activity
TCCBUS3UF1_RS04015	COG2353	YceI-like domain
TCCBUS3UF1_RS04020	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
TCCBUS3UF1_RS04025	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TCCBUS3UF1_RS04045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TCCBUS3UF1_RS04050	COG0179	Fumarylacetoacetate (FAA) hydrolase
TCCBUS3UF1_RS04060	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TCCBUS3UF1_RS04065	COG0151	Belongs to the GarS family
TCCBUS3UF1_RS04070	COG5002	protein histidine kinase activity
TCCBUS3UF1_RS04070	COG2176	DNA-directed DNA polymerase activity
TCCBUS3UF1_RS04080	COG2205	protein histidine kinase activity
TCCBUS3UF1_RS04085	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TCCBUS3UF1_RS04085	COG0617	tRNA 3'-terminal CCA addition
TCCBUS3UF1_RS04085	COG0517	IMP dehydrogenase activity
TCCBUS3UF1_RS04095	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TCCBUS3UF1_RS04105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TCCBUS3UF1_RS04110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TCCBUS3UF1_RS04115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TCCBUS3UF1_RS04125	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TCCBUS3UF1_RS04125	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TCCBUS3UF1_RS04135	COG1733	regulation of RNA biosynthetic process
TCCBUS3UF1_RS04140	COG2894	cell division
TCCBUS3UF1_RS04145	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
TCCBUS3UF1_RS04150	COG0772	Belongs to the SEDS family
TCCBUS3UF1_RS04155	COG3842	ATPase activity
TCCBUS3UF1_RS04160	COG1176	ABC-type spermidine putrescine transport system, permease component I
TCCBUS3UF1_RS04165	COG1177	transmembrane transport
TCCBUS3UF1_RS04175	COG2010	Cytochrome c
TCCBUS3UF1_RS04180	COG0129	dihydroxy-acid dehydratase activity
TCCBUS3UF1_RS04200	COG0066	3-isopropylmalate dehydratase activity
TCCBUS3UF1_RS04205	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TCCBUS3UF1_RS04215	COG0180	Tryptophanyl-tRNA synthetase
TCCBUS3UF1_RS04225	COG0438	transferase activity, transferring glycosyl groups
TCCBUS3UF1_RS04235	COG1216	Glycosyl transferase, family 2
TCCBUS3UF1_RS04250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TCCBUS3UF1_RS04270	COG2165	general secretion pathway protein
TCCBUS3UF1_RS04280	COG4966	pilus assembly protein PilW
TCCBUS3UF1_RS04285	COG2165	general secretion pathway protein
TCCBUS3UF1_RS04290	COG4970	Tfp pilus assembly protein FimT
TCCBUS3UF1_RS04295	COG4970	Tfp pilus assembly protein FimT
TCCBUS3UF1_RS04300	COG0183	Belongs to the thiolase family
TCCBUS3UF1_RS04315	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TCCBUS3UF1_RS04320	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TCCBUS3UF1_RS04335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TCCBUS3UF1_RS04340	COG1254	Belongs to the acylphosphatase family
TCCBUS3UF1_RS04350	COG1063	alcohol dehydrogenase
TCCBUS3UF1_RS04355	COG2133	pyrroloquinoline quinone binding
TCCBUS3UF1_RS04360	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TCCBUS3UF1_RS04390	COG0419	ATPase involved in DNA repair
TCCBUS3UF1_RS04410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TCCBUS3UF1_RS04415	COG0612	Peptidase, M16
TCCBUS3UF1_RS04420	COG0612	Peptidase, M16
TCCBUS3UF1_RS04425	COG0697	spore germination
TCCBUS3UF1_RS04430	COG1250	3-hydroxyacyl-CoA dehydrogenase
TCCBUS3UF1_RS04460	COG4956	integral membrane protein (PIN domain superfamily)
TCCBUS3UF1_RS04465	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TCCBUS3UF1_RS04470	COG0542	response to heat
TCCBUS3UF1_RS04475	COG0423	glycine-tRNA ligase activity
TCCBUS3UF1_RS04480	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
TCCBUS3UF1_RS04500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TCCBUS3UF1_RS04500	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TCCBUS3UF1_RS04505	COG1024	Enoyl-CoA hydratase
TCCBUS3UF1_RS04510	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TCCBUS3UF1_RS04520	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TCCBUS3UF1_RS04530	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TCCBUS3UF1_RS04535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TCCBUS3UF1_RS04540	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TCCBUS3UF1_RS04550	COG0861	Integral membrane protein TerC family
TCCBUS3UF1_RS04555	COG0492	ferredoxin-NADP+ reductase activity
TCCBUS3UF1_RS04560	COG0028	Belongs to the TPP enzyme family
TCCBUS3UF1_RS04565	COG0440	acetolactate synthase activity
TCCBUS3UF1_RS04570	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TCCBUS3UF1_RS04580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TCCBUS3UF1_RS04590	COG4555	ABC transporter
TCCBUS3UF1_RS04600	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TCCBUS3UF1_RS04610	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TCCBUS3UF1_RS04615	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TCCBUS3UF1_RS04620	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TCCBUS3UF1_RS04635	COG2322	membrane
TCCBUS3UF1_RS04645	COG0768	penicillin binding
TCCBUS3UF1_RS04660	COG0424	maF-like protein
TCCBUS3UF1_RS04665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TCCBUS3UF1_RS04670	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TCCBUS3UF1_RS04675	COG0012	GTP binding
TCCBUS3UF1_RS04695	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
TCCBUS3UF1_RS04705	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TCCBUS3UF1_RS04710	COG3001	Fructosamine kinase
TCCBUS3UF1_RS04720	COG2313	pseudouridylate synthase activity
TCCBUS3UF1_RS04730	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TCCBUS3UF1_RS04735	COG0569	domain protein
TCCBUS3UF1_RS04740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TCCBUS3UF1_RS04750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TCCBUS3UF1_RS04755	COG0765	amino acid transport
TCCBUS3UF1_RS04760	COG2358	TRAP transporter, solute receptor (TAXI family
TCCBUS3UF1_RS04770	COG1126	abc transporter atp-binding protein
TCCBUS3UF1_RS04785	COG3311	Transcriptional regulator
TCCBUS3UF1_RS04795	COG0134	indole-3-glycerol-phosphate synthase activity
TCCBUS3UF1_RS04800	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TCCBUS3UF1_RS04810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TCCBUS3UF1_RS04820	COG0525	valine-tRNA ligase activity
TCCBUS3UF1_RS04835	COG0489	protein tyrosine kinase activity
TCCBUS3UF1_RS04845	COG2264	protein methyltransferase activity
TCCBUS3UF1_RS04850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TCCBUS3UF1_RS04885	COG1175	transmembrane transport
TCCBUS3UF1_RS04895	COG1940	carbohydrate kinase activity
TCCBUS3UF1_RS04905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TCCBUS3UF1_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
TCCBUS3UF1_RS04955	COG1304	FMN binding
TCCBUS3UF1_RS04965	COG1216	Glycosyl transferase, family 2
TCCBUS3UF1_RS04990	COG1562	ergosterol biosynthetic process
TCCBUS3UF1_RS05010	COG2391	methyltransferase activity
TCCBUS3UF1_RS05060	COG0702	epimerase
TCCBUS3UF1_RS05065	COG1233	COG1233 Phytoene dehydrogenase and related
TCCBUS3UF1_RS05075	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TCCBUS3UF1_RS05090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TCCBUS3UF1_RS05110	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TCCBUS3UF1_RS05115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TCCBUS3UF1_RS05120	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TCCBUS3UF1_RS05125	COG0772	Belongs to the SEDS family
TCCBUS3UF1_RS05130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TCCBUS3UF1_RS05135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TCCBUS3UF1_RS05145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TCCBUS3UF1_RS05150	COG0768	penicillin binding
TCCBUS3UF1_RS05160	COG0275	rRNA processing
TCCBUS3UF1_RS05165	COG2001	Belongs to the MraZ family
TCCBUS3UF1_RS05175	COG0254	rRNA binding
TCCBUS3UF1_RS05180	COG1435	thymidine kinase activity
TCCBUS3UF1_RS05190	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TCCBUS3UF1_RS05195	COG0154	amidase activity
TCCBUS3UF1_RS05220	COG0572	uridine kinase
TCCBUS3UF1_RS05225	COG3842	ATPase activity
TCCBUS3UF1_RS05230	COG1970	mechanosensitive ion channel activity
TCCBUS3UF1_RS05240	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TCCBUS3UF1_RS05245	COG4475	Protein of unknown function (DUF436)
TCCBUS3UF1_RS05250	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TCCBUS3UF1_RS05255	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TCCBUS3UF1_RS05265	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
TCCBUS3UF1_RS05275	COG3870	Protein conserved in bacteria
TCCBUS3UF1_RS05280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TCCBUS3UF1_RS05300	COG0544	peptidyl-prolyl cis-trans isomerase activity
TCCBUS3UF1_RS05305	COG0740	serine-type endopeptidase activity
TCCBUS3UF1_RS05310	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TCCBUS3UF1_RS05315	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TCCBUS3UF1_RS05320	COG1410	methionine synthase
TCCBUS3UF1_RS05320	COG0646	methionine synthase
TCCBUS3UF1_RS05330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TCCBUS3UF1_RS05355	COG1692	metallophosphoesterase
TCCBUS3UF1_RS05370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TCCBUS3UF1_RS05380	COG2239	Acts as a magnesium transporter
TCCBUS3UF1_RS05390	COG0228	four-way junction DNA binding
TCCBUS3UF1_RS05400	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TCCBUS3UF1_RS05405	COG0336	Belongs to the RNA methyltransferase TrmD family
TCCBUS3UF1_RS05410	COG0335	large ribosomal subunit rRNA binding
TCCBUS3UF1_RS05415	COG2197	response regulator
TCCBUS3UF1_RS05420	COG1760	l-serine dehydratase
TCCBUS3UF1_RS05425	COG2897	thiosulfate sulfurtransferase activity
TCCBUS3UF1_RS05430	COG2738	Putative neutral zinc metallopeptidase
TCCBUS3UF1_RS05440	COG0450	alkyl hydroperoxide reductase
TCCBUS3UF1_RS05465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TCCBUS3UF1_RS05470	COG1268	BioY protein
TCCBUS3UF1_RS05480	COG0126	phosphoglycerate kinase activity
TCCBUS3UF1_RS05485	COG0149	triose-phosphate isomerase activity
TCCBUS3UF1_RS05515	COG0517	IMP dehydrogenase activity
TCCBUS3UF1_RS05515	COG0617	tRNA 3'-terminal CCA addition
TCCBUS3UF1_RS05515	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TCCBUS3UF1_RS05520	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TCCBUS3UF1_RS05525	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TCCBUS3UF1_RS05530	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TCCBUS3UF1_RS05535	COG2873	o-acetylhomoserine
TCCBUS3UF1_RS05550	COG0742	ribosomal rna small subunit methyltransferase
TCCBUS3UF1_RS05555	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TCCBUS3UF1_RS05565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TCCBUS3UF1_RS05570	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TCCBUS3UF1_RS05595	COG0395	ABC-type sugar transport system, permease component
TCCBUS3UF1_RS05600	COG1175	transmembrane transport
TCCBUS3UF1_RS05620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TCCBUS3UF1_RS05635	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TCCBUS3UF1_RS05640	COG0469	pyruvate kinase activity
TCCBUS3UF1_RS05655	COG0395	ABC-type sugar transport system, permease component
TCCBUS3UF1_RS05660	COG1175	transmembrane transport
TCCBUS3UF1_RS05665	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TCCBUS3UF1_RS05670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TCCBUS3UF1_RS05675	COG4558	Periplasmic binding protein
TCCBUS3UF1_RS05690	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TCCBUS3UF1_RS05700	COG0402	S-adenosylhomocysteine deaminase activity
TCCBUS3UF1_RS05710	COG4948	Mandelate Racemase Muconate Lactonizing
TCCBUS3UF1_RS05715	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TCCBUS3UF1_RS05720	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TCCBUS3UF1_RS05725	COG1811	Na channel or pump
TCCBUS3UF1_RS05730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TCCBUS3UF1_RS05730	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
TCCBUS3UF1_RS05745	COG1215	transferase activity, transferring glycosyl groups
TCCBUS3UF1_RS05760	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
TCCBUS3UF1_RS05775	COG1250	3-hydroxyacyl-CoA dehydrogenase
TCCBUS3UF1_RS05775	COG1024	Enoyl-CoA hydratase
TCCBUS3UF1_RS05780	COG0183	Belongs to the thiolase family
TCCBUS3UF1_RS05785	COG1960	acyl-CoA dehydrogenase activity
TCCBUS3UF1_RS05790	COG0215	cysteine-tRNA ligase activity
TCCBUS3UF1_RS05795	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
TCCBUS3UF1_RS05805	COG2873	o-acetylhomoserine
TCCBUS3UF1_RS05815	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TCCBUS3UF1_RS05815	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TCCBUS3UF1_RS05815	COG1013	pyruvate-flavodoxin oxidoreductase activity
TCCBUS3UF1_RS05815	COG0674	pyruvate-flavodoxin oxidoreductase activity
TCCBUS3UF1_RS05820	COG1304	FMN binding
TCCBUS3UF1_RS05830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TCCBUS3UF1_RS05830	COG1796	DNA polymerase
TCCBUS3UF1_RS05835	COG1573	uracil-dna glycosylase
TCCBUS3UF1_RS05845	COG2197	response regulator
TCCBUS3UF1_RS05850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TCCBUS3UF1_RS05860	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TCCBUS3UF1_RS05865	COG2086	electron transfer activity
TCCBUS3UF1_RS05870	COG1960	acyl-CoA dehydrogenase activity
TCCBUS3UF1_RS05880	COG5002	protein histidine kinase activity
TCCBUS3UF1_RS05885	COG0745	RESPONSE REGULATOR receiver
TCCBUS3UF1_RS05890	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TCCBUS3UF1_RS05895	COG3383	formate dehydrogenase (NAD+) activity
TCCBUS3UF1_RS05905	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TCCBUS3UF1_RS05910	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TCCBUS3UF1_RS05915	COG0803	Belongs to the bacterial solute-binding protein 9 family
TCCBUS3UF1_RS05920	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TCCBUS3UF1_RS05935	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TCCBUS3UF1_RS05940	COG3842	ATPase activity
TCCBUS3UF1_RS05945	COG1176	ABC-type spermidine putrescine transport system, permease component I
TCCBUS3UF1_RS05950	COG1177	transmembrane transport
TCCBUS3UF1_RS05955	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
TCCBUS3UF1_RS05975	COG2414	aldehyde ferredoxin oxidoreductase
TCCBUS3UF1_RS05980	COG1960	acyl-CoA dehydrogenase activity
TCCBUS3UF1_RS05990	COG0477	Major facilitator Superfamily
TCCBUS3UF1_RS05995	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TCCBUS3UF1_RS06000	COG0183	Belongs to the thiolase family
TCCBUS3UF1_RS06015	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TCCBUS3UF1_RS06020	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
TCCBUS3UF1_RS06025	COG2193	ferroxidase activity
TCCBUS3UF1_RS06030	COG1733	regulation of RNA biosynthetic process
TCCBUS3UF1_RS06035	COG1012	belongs to the aldehyde dehydrogenase family
TCCBUS3UF1_RS06035	COG2030	dehydratase
TCCBUS3UF1_RS06055	COG3396	Phenylacetate-CoA oxygenase
TCCBUS3UF1_RS06070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TCCBUS3UF1_RS06070	COG0574	Belongs to the PEP-utilizing enzyme family
TCCBUS3UF1_RS06085	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TCCBUS3UF1_RS06090	COG2050	protein possibly involved in aromatic compounds catabolism
TCCBUS3UF1_RS06120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TCCBUS3UF1_RS06125	COG2368	4-hydroxyphenylacetate
TCCBUS3UF1_RS06140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TCCBUS3UF1_RS06160	COG1136	(ABC) transporter
TCCBUS3UF1_RS06165	COG1136	(ABC) transporter
TCCBUS3UF1_RS06165	COG0577	efflux transmembrane transporter activity
TCCBUS3UF1_RS06185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TCCBUS3UF1_RS06190	COG1307	EDD domain protein, DegV family
TCCBUS3UF1_RS06195	COG1307	EDD domain protein, DegV family
TCCBUS3UF1_RS06200	COG1490	D-aminoacyl-tRNA deacylase activity
TCCBUS3UF1_RS06205	COG3239	Fatty acid desaturase
TCCBUS3UF1_RS06210	COG0138	bifunctional purine biosynthesis protein purh
TCCBUS3UF1_RS06220	COG0494	nUDIX hydrolase
TCCBUS3UF1_RS06225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TCCBUS3UF1_RS06235	COG1079	Belongs to the binding-protein-dependent transport system permease family
TCCBUS3UF1_RS06240	COG4603	Belongs to the binding-protein-dependent transport system permease family
TCCBUS3UF1_RS06245	COG1129	ABC transporter
TCCBUS3UF1_RS06250	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
TCCBUS3UF1_RS06260	COG0019	diaminopimelate decarboxylase activity
TCCBUS3UF1_RS06265	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
TCCBUS3UF1_RS06270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TCCBUS3UF1_RS06275	COG0601	transmembrane transport
TCCBUS3UF1_RS06280	COG0747	negative chemotaxis
TCCBUS3UF1_RS06290	COG1012	belongs to the aldehyde dehydrogenase family
TCCBUS3UF1_RS06305	COG0601	transmembrane transport
TCCBUS3UF1_RS06310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TCCBUS3UF1_RS06315	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TCCBUS3UF1_RS06340	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TCCBUS3UF1_RS06365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TCCBUS3UF1_RS06375	COG1802	Transcriptional regulator
TCCBUS3UF1_RS06390	COG0683	leucine binding
TCCBUS3UF1_RS06425	COG1942	4-Oxalocrotonate Tautomerase
TCCBUS3UF1_RS06470	COG1129	ABC transporter
TCCBUS3UF1_RS06495	COG3181	Tripartite tricarboxylate transporter family receptor
TCCBUS3UF1_RS06520	COG2323	membrane
TCCBUS3UF1_RS06535	COG1116	anion transmembrane transporter activity
TCCBUS3UF1_RS06560	COG1337	RAMP superfamily
TCCBUS3UF1_RS06580	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TCCBUS3UF1_RS06600	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TCCBUS3UF1_RS06605	COG1785	Belongs to the alkaline phosphatase family
TCCBUS3UF1_RS06610	COG0351	phosphomethylpyrimidine kinase
TCCBUS3UF1_RS06610	COG0352	thiamine-phosphate diphosphorylase activity
TCCBUS3UF1_RS06615	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TCCBUS3UF1_RS06620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TCCBUS3UF1_RS06620	COG2022	thiamine diphosphate biosynthetic process
TCCBUS3UF1_RS06625	COG2022	thiamine diphosphate biosynthetic process
TCCBUS3UF1_RS06630	COG2104	thiamine diphosphate biosynthetic process
TCCBUS3UF1_RS06635	COG0352	thiamine-phosphate diphosphorylase activity
TCCBUS3UF1_RS06640	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TCCBUS3UF1_RS06645	COG1587	Uroporphyrinogen-III synthase
TCCBUS3UF1_RS06650	COG1648	precorrin-2 dehydrogenase activity
TCCBUS3UF1_RS06650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TCCBUS3UF1_RS06655	COG0175	sulfate reduction
TCCBUS3UF1_RS06660	COG0730	response to heat
TCCBUS3UF1_RS06665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TCCBUS3UF1_RS06665	COG1648	precorrin-2 dehydrogenase activity
TCCBUS3UF1_RS06670	COG2046	Belongs to the sulfate adenylyltransferase family
TCCBUS3UF1_RS06685	COG0559	Belongs to the binding-protein-dependent transport system permease family
TCCBUS3UF1_RS06700	COG2030	dehydratase
TCCBUS3UF1_RS06710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TCCBUS3UF1_RS06745	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TCCBUS3UF1_RS06750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TCCBUS3UF1_RS06760	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TCCBUS3UF1_RS06765	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TCCBUS3UF1_RS06790	COG0438	transferase activity, transferring glycosyl groups
TCCBUS3UF1_RS06795	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TCCBUS3UF1_RS06805	COG0039	L-malate dehydrogenase activity
TCCBUS3UF1_RS06810	COG2819	hydrolase of the alpha beta superfamily
TCCBUS3UF1_RS06815	COG0861	Integral membrane protein TerC family
TCCBUS3UF1_RS06825	COG2181	nitrate reductase activity
TCCBUS3UF1_RS06825	COG0247	lactate metabolic process
TCCBUS3UF1_RS06835	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
TCCBUS3UF1_RS06840	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TCCBUS3UF1_RS06845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TCCBUS3UF1_RS06855	COG0439	Biotin carboxylase
TCCBUS3UF1_RS06860	COG0511	ligase activity, forming carbon-carbon bonds
TCCBUS3UF1_RS06865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TCCBUS3UF1_RS06875	COG1073	alpha beta
TCCBUS3UF1_RS06880	COG0010	Belongs to the arginase family
TCCBUS3UF1_RS06895	COG1100	Small GTP-binding protein
TCCBUS3UF1_RS06905	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TCCBUS3UF1_RS06910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TCCBUS3UF1_RS06925	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TCCBUS3UF1_RS06930	COG1185	polyribonucleotide nucleotidyltransferase activity
TCCBUS3UF1_RS06935	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TCCBUS3UF1_RS06950	COG0517	IMP dehydrogenase activity
TCCBUS3UF1_RS06950	COG1125	glycine betaine transport
TCCBUS3UF1_RS06955	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TCCBUS3UF1_RS06965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TCCBUS3UF1_RS06970	COG0165	Argininosuccinate lyase
TCCBUS3UF1_RS06990	COG0411	ABC transporter
TCCBUS3UF1_RS07005	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TCCBUS3UF1_RS07020	COG0237	dephospho-CoA kinase activity
TCCBUS3UF1_RS07025	COG0617	tRNA 3'-terminal CCA addition
TCCBUS3UF1_RS07025	COG1353	crispr-associated protein
TCCBUS3UF1_RS07030	COG1355	regulation of microtubule-based process
TCCBUS3UF1_RS07035	COG0557	exoribonuclease II activity
TCCBUS3UF1_RS07045	COG0824	Thioesterase
TCCBUS3UF1_RS07050	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TCCBUS3UF1_RS07055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TCCBUS3UF1_RS07070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TCCBUS3UF1_RS07075	COG0740	serine-type endopeptidase activity
TCCBUS3UF1_RS07080	COG4864	UPF0365 protein
TCCBUS3UF1_RS07090	COG1702	phosphate starvation-inducible protein PhoH
TCCBUS3UF1_RS07095	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TCCBUS3UF1_RS07120	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TCCBUS3UF1_RS07125	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TCCBUS3UF1_RS07125	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TCCBUS3UF1_RS07140	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TCCBUS3UF1_RS07160	COG2304	oxidoreductase activity
TCCBUS3UF1_RS07165	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TCCBUS3UF1_RS07165	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TCCBUS3UF1_RS07175	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TCCBUS3UF1_RS07175	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TCCBUS3UF1_RS07180	COG0779	Required for maturation of 30S ribosomal subunits
TCCBUS3UF1_RS07185	COG0195	Participates in both transcription termination and antitermination
TCCBUS3UF1_RS07195	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TCCBUS3UF1_RS07205	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TCCBUS3UF1_RS07205	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TCCBUS3UF1_RS07215	COG1028	Short-chain dehydrogenase reductase Sdr
TCCBUS3UF1_RS07220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TCCBUS3UF1_RS07230	COG0183	Belongs to the thiolase family
TCCBUS3UF1_RS07240	COG0481	GTPase activity
TCCBUS3UF1_RS07250	COG1760	l-serine dehydratase
TCCBUS3UF1_RS07260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TCCBUS3UF1_RS07300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TCCBUS3UF1_RS07310	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TCCBUS3UF1_RS07315	COG1394	ATPase activity, coupled to movement of substances
TCCBUS3UF1_RS07320	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TCCBUS3UF1_RS07325	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TCCBUS3UF1_RS07330	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
TCCBUS3UF1_RS07335	COG1527	subunit (C
TCCBUS3UF1_RS07340	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
TCCBUS3UF1_RS07350	COG1269	ATP hydrolysis coupled proton transport
TCCBUS3UF1_RS07360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TCCBUS3UF1_RS07380	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TCCBUS3UF1_RS07385	COG0515	serine threonine protein kinase
TCCBUS3UF1_RS07390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TCCBUS3UF1_RS07415	COG1316	TRANSCRIPTIONal
TCCBUS3UF1_RS07430	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TCCBUS3UF1_RS07450	COG1573	uracil-dna glycosylase
TCCBUS3UF1_RS07465	COG3842	ATPase activity
TCCBUS3UF1_RS07475	COG0124	histidyl-tRNA synthetase
TCCBUS3UF1_RS07485	COG0384	phenazine biosynthesis protein PhzF
TCCBUS3UF1_RS07490	COG0561	phosphatase activity
TCCBUS3UF1_RS07495	COG0017	Asparaginyl-tRNA synthetase
TCCBUS3UF1_RS07500	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TCCBUS3UF1_RS07510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TCCBUS3UF1_RS07515	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
TCCBUS3UF1_RS07520	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
TCCBUS3UF1_RS07530	COG0640	Transcriptional regulator
TCCBUS3UF1_RS07535	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
TCCBUS3UF1_RS07540	COG0739	heme binding
TCCBUS3UF1_RS07545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TCCBUS3UF1_RS07550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TCCBUS3UF1_RS07555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TCCBUS3UF1_RS07560	COG0006	proline dipeptidase activity
TCCBUS3UF1_RS07565	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TCCBUS3UF1_RS07570	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
TCCBUS3UF1_RS07575	COG1994	Peptidase M50
TCCBUS3UF1_RS07585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TCCBUS3UF1_RS07585	COG0617	tRNA 3'-terminal CCA addition
TCCBUS3UF1_RS07585	COG0517	IMP dehydrogenase activity
TCCBUS3UF1_RS07605	COG0052	Belongs to the universal ribosomal protein uS2 family
TCCBUS3UF1_RS07610	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TCCBUS3UF1_RS07615	COG0528	UMP kinase activity
TCCBUS3UF1_RS07620	COG0233	cytoplasmic translational termination
TCCBUS3UF1_RS07625	COG4589	Belongs to the CDS family
TCCBUS3UF1_RS07630	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TCCBUS3UF1_RS07635	COG0750	zinc metalloprotease
TCCBUS3UF1_RS07650	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TCCBUS3UF1_RS07655	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TCCBUS3UF1_RS07660	COG2359	stage V sporulation protein S
TCCBUS3UF1_RS07670	COG2137	regulation of response to DNA damage stimulus
TCCBUS3UF1_RS07690	COG2766	serine protein kinase
TCCBUS3UF1_RS07700	COG2719	SpoVR family
TCCBUS3UF1_RS07705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TCCBUS3UF1_RS07710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TCCBUS3UF1_RS07725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TCCBUS3UF1_RS07740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TCCBUS3UF1_RS07745	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TCCBUS3UF1_RS07750	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
TCCBUS3UF1_RS07755	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
TCCBUS3UF1_RS07760	COG3706	GGDEF domain
TCCBUS3UF1_RS07775	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TCCBUS3UF1_RS07780	COG3191	aminopeptidase activity
TCCBUS3UF1_RS07790	COG1063	alcohol dehydrogenase
TCCBUS3UF1_RS07795	COG0714	Associated with various cellular activities
TCCBUS3UF1_RS07805	COG2304	oxidoreductase activity
TCCBUS3UF1_RS07810	COG2304	oxidoreductase activity
TCCBUS3UF1_RS07820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TCCBUS3UF1_RS07835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
TCCBUS3UF1_RS07840	COG2884	Cell division ATP-binding protein ftsE
TCCBUS3UF1_RS07845	COG0793	Belongs to the peptidase S41A family
TCCBUS3UF1_RS07850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TCCBUS3UF1_RS07850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TCCBUS3UF1_RS07855	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TCCBUS3UF1_RS07860	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TCCBUS3UF1_RS07870	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TCCBUS3UF1_RS07875	COG0159	tryptophan synthase activity
TCCBUS3UF1_RS07880	COG0133	tryptophan synthase activity
TCCBUS3UF1_RS07885	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TCCBUS3UF1_RS07895	COG1744	ABC transporter substrate-binding protein PnrA-like
TCCBUS3UF1_RS07900	COG3845	ABC transporter
TCCBUS3UF1_RS07925	COG0745	RESPONSE REGULATOR receiver
TCCBUS3UF1_RS07930	COG0077	Prephenate dehydratase
TCCBUS3UF1_RS07930	COG1605	Chorismate mutase
TCCBUS3UF1_RS07935	COG0517	IMP dehydrogenase activity
TCCBUS3UF1_RS07950	COG1674	ftsk spoiiie
TCCBUS3UF1_RS07955	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TCCBUS3UF1_RS07960	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TCCBUS3UF1_RS07965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
TCCBUS3UF1_RS07970	COG4651	solute:proton antiporter activity
TCCBUS3UF1_RS07970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TCCBUS3UF1_RS07975	COG0217	transcriptional regulatory protein
TCCBUS3UF1_RS07985	COG0653	protein targeting
TCCBUS3UF1_RS07990	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TCCBUS3UF1_RS08010	COG1960	acyl-CoA dehydrogenase activity
TCCBUS3UF1_RS08020	COG0312	modulator of DNA gyrase
TCCBUS3UF1_RS08025	COG0312	modulator of DNA gyrase
TCCBUS3UF1_RS08035	COG0730	response to heat
TCCBUS3UF1_RS08055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TCCBUS3UF1_RS08065	COG0167	dihydroorotate dehydrogenase activity
TCCBUS3UF1_RS08075	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TCCBUS3UF1_RS08080	COG0746	molybdenum cofactor guanylyltransferase activity
TCCBUS3UF1_RS08095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TCCBUS3UF1_RS08115	COG0473	3-isopropylmalate dehydrogenase activity
TCCBUS3UF1_RS08120	COG0538	isocitrate dehydrogenase activity
TCCBUS3UF1_RS08125	COG0557	exoribonuclease II activity
TCCBUS3UF1_RS08145	COG0585	pseudouridine synthase activity
TCCBUS3UF1_RS08165	COG2050	protein possibly involved in aromatic compounds catabolism
TCCBUS3UF1_RS08175	COG0322	excinuclease ABC activity
TCCBUS3UF1_RS08180	COG0018	arginyl-trna synthetase
TCCBUS3UF1_RS08185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TCCBUS3UF1_RS08190	COG1428	Deoxynucleoside kinase
TCCBUS3UF1_RS08195	COG1428	Deoxynucleoside kinase
TCCBUS3UF1_RS08200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TCCBUS3UF1_RS08205	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
TCCBUS3UF1_RS08210	COG0107	imidazoleglycerol-phosphate synthase activity
TCCBUS3UF1_RS08215	COG0140	phosphoribosyl-ATP diphosphatase activity
TCCBUS3UF1_RS08215	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TCCBUS3UF1_RS08220	COG1494	fructose-1,6-bisphosphatase
TCCBUS3UF1_RS08255	COG0084	hydrolase, TatD family'
TCCBUS3UF1_RS08260	COG0017	Asparaginyl-tRNA synthetase
TCCBUS3UF1_RS08265	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TCCBUS3UF1_RS08280	COG2009	succinate dehydrogenase
TCCBUS3UF1_RS08285	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TCCBUS3UF1_RS08295	COG1131	(ABC) transporter
TCCBUS3UF1_RS08315	COG0318	PFAM AMP-dependent synthetase and ligase
TCCBUS3UF1_RS08320	COG1104	cysteine desulfurase activity
TCCBUS3UF1_RS08325	COG1959	2 iron, 2 sulfur cluster binding
TCCBUS3UF1_RS08330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TCCBUS3UF1_RS08335	COG1121	(ABC) transporter
TCCBUS3UF1_RS08360	COG0318	PFAM AMP-dependent synthetase and ligase
TCCBUS3UF1_RS08375	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TCCBUS3UF1_RS08380	COG0706	membrane insertase activity
TCCBUS3UF1_RS08385	COG1837	Belongs to the UPF0109 family
TCCBUS3UF1_RS08390	COG2890	protein-(glutamine-N5) methyltransferase activity
TCCBUS3UF1_RS08405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TCCBUS3UF1_RS08420	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
TCCBUS3UF1_RS08435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TCCBUS3UF1_RS08440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TCCBUS3UF1_RS08445	COG0318	PFAM AMP-dependent synthetase and ligase
TCCBUS3UF1_RS08460	COG1024	Enoyl-CoA hydratase
TCCBUS3UF1_RS08465	COG0813	purine-nucleoside phosphorylase activity
TCCBUS3UF1_RS08470	COG1136	(ABC) transporter
TCCBUS3UF1_RS08475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TCCBUS3UF1_RS08480	COG2045	Belongs to the ComB family
TCCBUS3UF1_RS08490	COG0789	Transcriptional regulator
TCCBUS3UF1_RS08495	COG1414	Transcriptional regulator
TCCBUS3UF1_RS08500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
TCCBUS3UF1_RS08505	COG0277	FAD linked oxidase domain protein
TCCBUS3UF1_RS08510	COG0277	FAD linked oxidase domain protein
TCCBUS3UF1_RS08515	COG0247	lactate metabolic process
TCCBUS3UF1_RS08525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TCCBUS3UF1_RS08625	COG1518	maintenance of DNA repeat elements
TCCBUS3UF1_RS08640	COG2002	toxin-antitoxin pair type II binding
TCCBUS3UF1_RS08730	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TCCBUS3UF1_RS08735	COG0460	homoserine dehydrogenase
TCCBUS3UF1_RS08740	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TCCBUS3UF1_RS08765	COG2226	methyltransferase
TCCBUS3UF1_RS08770	COG2226	methyltransferase
TCCBUS3UF1_RS08775	COG0366	Alpha amylase catalytic
TCCBUS3UF1_RS08780	COG0037	tRNA processing
TCCBUS3UF1_RS08785	COG2104	thiamine diphosphate biosynthetic process
TCCBUS3UF1_RS08790	COG0123	including yeast histone deacetylase and acetoin utilization protein
TCCBUS3UF1_RS08795	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TCCBUS3UF1_RS08795	COG0617	tRNA 3'-terminal CCA addition
TCCBUS3UF1_RS08795	COG0517	IMP dehydrogenase activity
TCCBUS3UF1_RS08805	COG0444	Belongs to the ABC transporter superfamily
TCCBUS3UF1_RS08810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TCCBUS3UF1_RS08815	COG0601	transmembrane transport
TCCBUS3UF1_RS08820	COG0747	negative chemotaxis
TCCBUS3UF1_RS08825	COG1063	alcohol dehydrogenase
TCCBUS3UF1_RS08830	COG0492	ferredoxin-NADP+ reductase activity
TCCBUS3UF1_RS08860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TCCBUS3UF1_RS08865	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TCCBUS3UF1_RS08870	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TCCBUS3UF1_RS08890	COG2070	2-Nitropropane dioxygenase
TCCBUS3UF1_RS08910	COG0745	RESPONSE REGULATOR receiver
TCCBUS3UF1_RS08915	COG5002	protein histidine kinase activity
TCCBUS3UF1_RS08930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TCCBUS3UF1_RS08950	COG0513	Belongs to the DEAD box helicase family
TCCBUS3UF1_RS08955	COG0303	'Molybdopterin
TCCBUS3UF1_RS08965	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TCCBUS3UF1_RS08970	COG0442	prolyl-tRNA aminoacylation
TCCBUS3UF1_RS08980	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TCCBUS3UF1_RS08985	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TCCBUS3UF1_RS08990	COG1028	Short-chain dehydrogenase reductase Sdr
TCCBUS3UF1_RS09000	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TCCBUS3UF1_RS09000	COG1213	nucleotidyl transferase
TCCBUS3UF1_RS09005	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TCCBUS3UF1_RS09010	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TCCBUS3UF1_RS09030	COG1515	deoxyribonuclease V activity
TCCBUS3UF1_RS09040	COG0776	regulation of translation
TCCBUS3UF1_RS09045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TCCBUS3UF1_RS09050	COG0443	Heat shock 70 kDa protein
TCCBUS3UF1_RS09055	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TCCBUS3UF1_RS09060	COG0484	heat shock protein binding
TCCBUS3UF1_RS09065	COG0789	Transcriptional regulator
TCCBUS3UF1_RS09070	COG0542	response to heat
TCCBUS3UF1_RS09095	COG3118	belongs to the thioredoxin family
TCCBUS3UF1_RS09115	COG0490	domain, Protein
TCCBUS3UF1_RS09120	COG0475	glutathione-regulated potassium exporter activity
TCCBUS3UF1_RS09135	COG4109	DRTGG domain
TCCBUS3UF1_RS09140	COG0475	glutathione-regulated potassium exporter activity
TCCBUS3UF1_RS09150	COG0305	Participates in initiation and elongation during chromosome replication
TCCBUS3UF1_RS09160	COG0067	glutamate synthase
TCCBUS3UF1_RS09160	COG0069	glutamate synthase activity
TCCBUS3UF1_RS09160	COG0070	glutamate synthase
TCCBUS3UF1_RS09175	COG0517	IMP dehydrogenase activity
TCCBUS3UF1_RS09175	COG0516	GMP reductase activity
TCCBUS3UF1_RS09185	COG0745	RESPONSE REGULATOR receiver
TCCBUS3UF1_RS09190	COG2205	protein histidine kinase activity
TCCBUS3UF1_RS09195	COG0704	Plays a role in the regulation of phosphate uptake
TCCBUS3UF1_RS09205	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TCCBUS3UF1_RS09215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TCCBUS3UF1_RS09225	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TCCBUS3UF1_RS09225	COG0515	serine threonine protein kinase
TCCBUS3UF1_RS09250	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TCCBUS3UF1_RS09255	COG1028	Short-chain dehydrogenase reductase Sdr
TCCBUS3UF1_RS09260	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TCCBUS3UF1_RS09260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TCCBUS3UF1_RS09270	COG0717	Belongs to the dCTP deaminase family
TCCBUS3UF1_RS09280	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
TCCBUS3UF1_RS09285	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TCCBUS3UF1_RS09290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TCCBUS3UF1_RS09300	COG0583	DNA-binding transcription factor activity
TCCBUS3UF1_RS09305	COG3546	catalase activity
TCCBUS3UF1_RS09310	COG0758	DNA mediated transformation
TCCBUS3UF1_RS09310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TCCBUS3UF1_RS09315	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TCCBUS3UF1_RS09325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TCCBUS3UF1_RS09330	COG0372	Belongs to the citrate synthase family
TCCBUS3UF1_RS09340	COG0616	signal peptide processing
TCCBUS3UF1_RS09345	COG1714	RDD family
TCCBUS3UF1_RS09390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TCCBUS3UF1_RS09400	COG0142	geranyltranstransferase activity
TCCBUS3UF1_RS09420	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TCCBUS3UF1_RS09425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TCCBUS3UF1_RS09435	COG0297	glycogen (starch) synthase activity
TCCBUS3UF1_RS09440	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
TCCBUS3UF1_RS09440	COG2105	PFAM AIG2 family protein
TCCBUS3UF1_RS09445	COG0745	RESPONSE REGULATOR receiver
TCCBUS3UF1_RS09455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TCCBUS3UF1_RS09460	COG1067	ATP-dependent peptidase activity
TCCBUS3UF1_RS09480	COG0667	Aldo Keto reductase
TCCBUS3UF1_RS09495	COG0277	FAD linked oxidase domain protein
TCCBUS3UF1_RS09505	COG2154	pterin-4-alpha-carbinolamine dehydratase
TCCBUS3UF1_RS09510	COG1607	acyl-coa hydrolase
TCCBUS3UF1_RS09520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TCCBUS3UF1_RS09525	COG4149	molybdate abc transporter
TCCBUS3UF1_RS09545	COG0235	Class ii aldolase
TCCBUS3UF1_RS09565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TCCBUS3UF1_RS09570	COG1077	Cell shape determining protein MreB Mrl
TCCBUS3UF1_RS09575	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TCCBUS3UF1_RS09575	COG1418	mRNA catabolic process
TCCBUS3UF1_RS09585	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TCCBUS3UF1_RS09590	COG1546	Belongs to the CinA family
TCCBUS3UF1_RS09590	COG1058	Belongs to the CinA family
TCCBUS3UF1_RS09595	COG0354	folic acid binding
TCCBUS3UF1_RS09610	COG4948	Mandelate Racemase Muconate Lactonizing
TCCBUS3UF1_RS09630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TCCBUS3UF1_RS09635	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
TCCBUS3UF1_RS09645	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TCCBUS3UF1_RS09655	COG0577	efflux transmembrane transporter activity
TCCBUS3UF1_RS09655	COG1136	(ABC) transporter
TCCBUS3UF1_RS09660	COG4181	ATPase activity
TCCBUS3UF1_RS09665	COG0446	pyridine nucleotide-disulphide oxidoreductase
TCCBUS3UF1_RS09680	COG0396	ATPase activity
TCCBUS3UF1_RS09685	COG0719	Fe-S assembly protein
TCCBUS3UF1_RS09690	COG0719	Fe-S assembly protein
TCCBUS3UF1_RS09715	COG2217	Heavy metal translocating P-type atpase
TCCBUS3UF1_RS09730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TCCBUS3UF1_RS09735	COG0822	iron-sulfur transferase activity
TCCBUS3UF1_RS09750	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TCCBUS3UF1_RS09760	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TCCBUS3UF1_RS09765	COG0284	orotidine-5'-phosphate decarboxylase activity
TCCBUS3UF1_RS09775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TCCBUS3UF1_RS09785	COG0416	fatty acid biosynthetic process
TCCBUS3UF1_RS09790	COG3118	belongs to the thioredoxin family
TCCBUS3UF1_RS09795	COG1185	polyribonucleotide nucleotidyltransferase activity
TCCBUS3UF1_RS09800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TCCBUS3UF1_RS09805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TCCBUS3UF1_RS09810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TCCBUS3UF1_RS09850	COG0437	4 iron, 4 sulfur cluster binding
TCCBUS3UF1_RS09885	COG1309	transcriptional regulator
TCCBUS3UF1_RS09900	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TCCBUS3UF1_RS09905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TCCBUS3UF1_RS09910	COG1968	undecaprenyl-diphosphatase activity
TCCBUS3UF1_RS09915	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TCCBUS3UF1_RS09920	COG0484	heat shock protein binding
TCCBUS3UF1_RS09925	COG1278	Cold shock
TCCBUS3UF1_RS09935	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TCCBUS3UF1_RS09960	COG0825	malonyl-CoA metabolic process
TCCBUS3UF1_RS09965	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TCCBUS3UF1_RS09975	COG0739	heme binding
TCCBUS3UF1_RS09995	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
TCCBUS3UF1_RS10005	COG0799	negative regulation of ribosome biogenesis
TCCBUS3UF1_RS10020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TCCBUS3UF1_RS10025	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TCCBUS3UF1_RS10030	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TCCBUS3UF1_RS10035	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TCCBUS3UF1_RS10055	COG2759	Belongs to the formate--tetrahydrofolate ligase family
TCCBUS3UF1_RS10060	COG0505	Belongs to the CarA family
TCCBUS3UF1_RS10070	COG0165	Argininosuccinate lyase
TCCBUS3UF1_RS10075	COG0137	argininosuccinate synthase activity
TCCBUS3UF1_RS10085	COG1404	Belongs to the peptidase S8 family
TCCBUS3UF1_RS10090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TCCBUS3UF1_RS10095	COG0508	dehydrogenase complex catalyzes the overall conversion of
TCCBUS3UF1_RS10105	COG1024	Enoyl-CoA hydratase
TCCBUS3UF1_RS10110	COG0632	four-way junction helicase activity
TCCBUS3UF1_RS10115	COG2205	protein histidine kinase activity
TCCBUS3UF1_RS10120	COG0745	RESPONSE REGULATOR receiver
TCCBUS3UF1_RS10145	COG3253	May function as heme-dependent peroxidase
TCCBUS3UF1_RS10150	COG0668	transmembrane transport
TCCBUS3UF1_RS10160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TCCBUS3UF1_RS10165	COG0432	Pfam Uncharacterised protein family UPF0047
TCCBUS3UF1_RS10170	COG2226	methyltransferase
TCCBUS3UF1_RS10195	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
TCCBUS3UF1_RS10200	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TCCBUS3UF1_RS10205	COG0022	dehydrogenase e1 component
TCCBUS3UF1_RS10215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TCCBUS3UF1_RS10230	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TCCBUS3UF1_RS10235	COG0321	lipoyl(octanoyl) transferase activity
TCCBUS3UF1_RS10245	COG0300	oxidoreductase activity
TCCBUS3UF1_RS10255	COG0359	binds to the 23S rRNA
TCCBUS3UF1_RS10260	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TCCBUS3UF1_RS10285	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
TCCBUS3UF1_RS10300	COG0697	spore germination
TCCBUS3UF1_RS10330	COG1803	Methylglyoxal synthase
TCCBUS3UF1_RS10335	COG1363	Peptidase, m42
TCCBUS3UF1_RS10340	COG1694	Mazg nucleotide pyrophosphohydrolase
TCCBUS3UF1_RS10345	COG1131	(ABC) transporter
TCCBUS3UF1_RS10360	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TCCBUS3UF1_RS10365	COG1950	PFAM Membrane protein of
TCCBUS3UF1_RS10370	COG0517	IMP dehydrogenase activity
TCCBUS3UF1_RS10370	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TCCBUS3UF1_RS10395	COG0033	Phosphoglucomutase
TCCBUS3UF1_RS10410	COG1653	transport
TCCBUS3UF1_RS10430	COG2414	aldehyde ferredoxin oxidoreductase
TCCBUS3UF1_RS10435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TCCBUS3UF1_RS10460	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
TCCBUS3UF1_RS10470	COG3942	CHAP domain
TCCBUS3UF1_RS10470	COG1388	LysM domain
TCCBUS3UF1_RS10490	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TCCBUS3UF1_RS10495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TCCBUS3UF1_RS10495	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TCCBUS3UF1_RS10500	COG1543	Belongs to the glycosyl hydrolase 57 family
TCCBUS3UF1_RS10505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TCCBUS3UF1_RS10510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TCCBUS3UF1_RS10515	COG0189	ligase activity
TCCBUS3UF1_RS10530	COG0066	3-isopropylmalate dehydratase activity
TCCBUS3UF1_RS10535	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TCCBUS3UF1_RS10540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TCCBUS3UF1_RS10545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TCCBUS3UF1_RS10550	COG1960	acyl-CoA dehydrogenase activity
TCCBUS3UF1_RS10555	COG0163	prenyltransferase activity
TCCBUS3UF1_RS10560	COG0222	ribosome binding
TCCBUS3UF1_RS10565	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TCCBUS3UF1_RS10570	COG0081	regulation of translation
TCCBUS3UF1_RS10580	COG0250	Participates in transcription elongation, termination and antitermination
TCCBUS3UF1_RS10585	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TCCBUS3UF1_RS10590	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TCCBUS3UF1_RS10620	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TCCBUS3UF1_RS10625	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TCCBUS3UF1_RS10630	COG1335	isochorismatase
TCCBUS3UF1_RS10645	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TCCBUS3UF1_RS10655	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TCCBUS3UF1_RS10660	COG1993	acr, cog1993
TCCBUS3UF1_RS10665	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TCCBUS3UF1_RS10670	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TCCBUS3UF1_RS10680	COG1496	oxidoreductase activity
TCCBUS3UF1_RS10685	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
TCCBUS3UF1_RS10690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
TCCBUS3UF1_RS10700	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TCCBUS3UF1_RS10705	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TCCBUS3UF1_RS10735	COG1355	regulation of microtubule-based process
TCCBUS3UF1_RS10745	COG1011	Hydrolase
TCCBUS3UF1_RS10760	COG0589	response to stress
TCCBUS3UF1_RS10765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TCCBUS3UF1_RS10770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TCCBUS3UF1_RS10825	COG0302	gtp cyclohydrolase
TCCBUS3UF1_RS10845	COG1217	gtp-binding protein TYPA
TCCBUS3UF1_RS10855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TCCBUS3UF1_RS10870	COG0395	ABC-type sugar transport system, permease component
TCCBUS3UF1_RS10880	COG1131	(ABC) transporter
TCCBUS3UF1_RS10900	COG0556	nucleotide-excision repair
TCCBUS3UF1_RS10910	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TCCBUS3UF1_RS10955	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TCCBUS3UF1_RS10970	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
TCCBUS3UF1_RS10975	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
TCCBUS3UF1_RS10995	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
TCCBUS3UF1_RS11000	COG0346	lactoylglutathione lyase activity
TCCBUS3UF1_RS11005	COG0400	carboxylic ester hydrolase activity
TCCBUS3UF1_RS11010	COG0497	DNA recombination
TCCBUS3UF1_RS11020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TCCBUS3UF1_RS11025	COG0343	queuine tRNA-ribosyltransferase activity
TCCBUS3UF1_RS11035	COG0628	permease
TCCBUS3UF1_RS11045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TCCBUS3UF1_RS11050	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TCCBUS3UF1_RS11055	COG0436	Aminotransferase
TCCBUS3UF1_RS11060	COG1597	lipid kinase activity
TCCBUS3UF1_RS11070	COG0456	acetyltransferase
TCCBUS3UF1_RS11075	COG0123	including yeast histone deacetylase and acetoin utilization protein
TCCBUS3UF1_RS11085	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
TCCBUS3UF1_RS11095	COG0004	ammonium transporteR
TCCBUS3UF1_RS11100	COG0347	Belongs to the P(II) protein family
TCCBUS3UF1_RS11105	COG1420	regulation of RNA biosynthetic process
TCCBUS3UF1_RS11110	COG0314	molybdopterin synthase activity
TCCBUS3UF1_RS11120	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TCCBUS3UF1_RS11125	COG1960	acyl-CoA dehydrogenase activity
TCCBUS3UF1_RS11135	COG0495	leucyl-tRNA aminoacylation
TCCBUS3UF1_RS11145	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TCCBUS3UF1_RS11150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TCCBUS3UF1_RS11180	COG2096	Adenosyltransferase
TCCBUS3UF1_RS11190	COG4555	ABC transporter
TCCBUS3UF1_RS11195	COG1668	transmembrane transport
TCCBUS3UF1_RS11220	COG1660	Displays ATPase and GTPase activities
TCCBUS3UF1_RS11225	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TCCBUS3UF1_RS11240	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TCCBUS3UF1_RS11245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TCCBUS3UF1_RS11265	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TCCBUS3UF1_RS11265	COG0072	phenylalanine-tRNA ligase activity
TCCBUS3UF1_RS11275	COG0205	6-phosphofructokinase activity
TCCBUS3UF1_RS11280	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TCCBUS3UF1_RS11290	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
TCCBUS3UF1_RS11295	COG0584	glycerophosphoryl diester phosphodiesterase
TCCBUS3UF1_RS11305	COG1555	photosystem II stabilization
TCCBUS3UF1_RS11310	COG2333	competence protein COMEC
TCCBUS3UF1_RS11310	COG0658	competence protein
TCCBUS3UF1_RS11315	COG1475	DNA binding
TCCBUS3UF1_RS11320	COG1192	Involved in chromosome partitioning
TCCBUS3UF1_RS11325	COG0357	Ribosomal RNA small subunit methyltransferase G
TCCBUS3UF1_RS11380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TCCBUS3UF1_RS11390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TCCBUS3UF1_RS11460	COG5297	Belongs to the glycosyl hydrolase family 6
TCCBUS3UF1_RS11460	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
TCCBUS3UF1_RS11465	COG1692	metallophosphoesterase
TCCBUS3UF1_RS11470	COG1692	metallophosphoesterase