locus-tag	class	description
FPG73_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FPG73_RS00010	COG0592	DNA-directed DNA polymerase activity
FPG73_RS00015	COG0148	phosphopyruvate hydratase activity
FPG73_RS00020	COG0469	pyruvate kinase activity
FPG73_RS00030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPG73_RS00035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FPG73_RS00045	COG1842	Phage shock protein A
FPG73_RS00080	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FPG73_RS00085	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FPG73_RS00095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FPG73_RS00100	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FPG73_RS00105	COG1496	oxidoreductase activity
FPG73_RS00110	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FPG73_RS00115	COG1278	Cold shock
FPG73_RS00120	COG1653	transport
FPG73_RS00135	COG0033	Phosphoglucomutase
FPG73_RS00160	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FPG73_RS00160	COG0517	IMP dehydrogenase activity
FPG73_RS00165	COG1950	PFAM Membrane protein of
FPG73_RS00170	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FPG73_RS00175	COG1047	Peptidyl-prolyl cis-trans
FPG73_RS00180	COG0181	hydroxymethylbilane synthase activity
FPG73_RS00190	COG0285	dihydrofolate synthase activity
FPG73_RS00195	COG0436	Aminotransferase
FPG73_RS00200	COG0521	Mo-molybdopterin cofactor biosynthetic process
FPG73_RS00220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FPG73_RS00225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FPG73_RS00230	COG1993	acr, cog1993
FPG73_RS00235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FPG73_RS00245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FPG73_RS00255	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FPG73_RS00260	COG1335	isochorismatase
FPG73_RS00265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FPG73_RS00280	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FPG73_RS00285	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FPG73_RS00305	COG1660	Displays ATPase and GTPase activities
FPG73_RS00310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FPG73_RS00355	COG3335	DDE superfamily endonuclease
FPG73_RS00380	COG1845	cytochrome c oxidase, subunit III
FPG73_RS00380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FPG73_RS00385	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FPG73_RS00385	COG2010	Cytochrome c
FPG73_RS00390	COG1612	heme a metabolic process
FPG73_RS00390	COG0109	protoheme IX farnesyltransferase activity
FPG73_RS00405	COG0343	queuine tRNA-ribosyltransferase activity
FPG73_RS00410	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FPG73_RS00415	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FPG73_RS00475	COG1940	carbohydrate kinase activity
FPG73_RS00485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPG73_RS00490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FPG73_RS00495	COG0589	response to stress
FPG73_RS00500	COG1611	Belongs to the LOG family
FPG73_RS00510	COG1011	Hydrolase
FPG73_RS00515	COG0632	four-way junction helicase activity
FPG73_RS00520	COG1024	Enoyl-CoA hydratase
FPG73_RS00530	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPG73_RS00540	COG0137	argininosuccinate synthase activity
FPG73_RS00545	COG0165	Argininosuccinate lyase
FPG73_RS00565	COG0505	Belongs to the CarA family
FPG73_RS00575	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FPG73_RS00580	COG0166	Belongs to the GPI family
FPG73_RS00590	COG0714	Associated with various cellular activities
FPG73_RS00605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FPG73_RS00610	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FPG73_RS00615	COG0459	protein refolding
FPG73_RS00620	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FPG73_RS00625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FPG73_RS00635	COG0778	Nitroreductase
FPG73_RS00640	COG0791	NLP P60 protein
FPG73_RS00640	COG1388	LysM domain
FPG73_RS00650	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FPG73_RS00660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FPG73_RS00665	COG0581	inorganic phosphate transmembrane transporter activity
FPG73_RS00670	COG0573	inorganic phosphate transmembrane transporter activity
FPG73_RS00680	COG0482	sulfurtransferase activity
FPG73_RS00690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FPG73_RS00695	COG0735	belongs to the Fur family
FPG73_RS00710	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FPG73_RS00735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FPG73_RS00740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FPG73_RS00745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FPG73_RS00750	COG0250	Participates in transcription elongation, termination and antitermination
FPG73_RS00775	COG0629	single-stranded DNA binding
FPG73_RS00780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FPG73_RS00785	COG0359	binds to the 23S rRNA
FPG73_RS00805	COG0300	oxidoreductase activity
FPG73_RS00810	COG0321	lipoyl(octanoyl) transferase activity
FPG73_RS00815	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FPG73_RS00840	COG1476	TRANSCRIPTIONal
FPG73_RS00860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FPG73_RS00875	COG1598	PFAM Uncharacterised protein family UPF0150
FPG73_RS00880	COG0022	dehydrogenase e1 component
FPG73_RS00885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FPG73_RS00890	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FPG73_RS00915	COG2226	methyltransferase
FPG73_RS00920	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FPG73_RS00930	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FPG73_RS00935	COG1187	pseudouridine synthase activity
FPG73_RS00945	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FPG73_RS00950	COG0686	Belongs to the AlaDH PNT family
FPG73_RS00960	COG1461	Dihydroxyacetone kinase
FPG73_RS00975	COG4591	ABC-type transport system involved in lipoprotein release permease component
FPG73_RS00980	COG0222	ribosome binding
FPG73_RS00985	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FPG73_RS00995	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FPG73_RS01010	COG0697	spore germination
FPG73_RS01025	COG3177	Filamentation induced by cAMP protein fic
FPG73_RS01035	COG0243	molybdopterin cofactor binding
FPG73_RS01045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FPG73_RS01055	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FPG73_RS01070	COG0477	Major facilitator Superfamily
FPG73_RS01085	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FPG73_RS01095	COG0105	UTP biosynthetic process
FPG73_RS01100	COG0631	protein serine/threonine phosphatase activity
FPG73_RS01105	COG0583	DNA-binding transcription factor activity
FPG73_RS01115	COG0508	dehydrogenase complex catalyzes the overall conversion of
FPG73_RS01145	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FPG73_RS01155	COG1278	Cold shock
FPG73_RS01160	COG0484	heat shock protein binding
FPG73_RS01165	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FPG73_RS01170	COG1968	undecaprenyl-diphosphatase activity
FPG73_RS01175	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FPG73_RS01180	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FPG73_RS01195	COG1309	transcriptional regulator
FPG73_RS01200	COG4242	Belongs to the peptidase S51 family
FPG73_RS01215	COG0802	atpase or kinase
FPG73_RS01225	COG0539	negative regulation of cytoplasmic translation
FPG73_RS01230	COG0495	leucyl-tRNA aminoacylation
FPG73_RS01250	COG1902	pentaerythritol trinitrate reductase activity
FPG73_RS01275	COG2414	aldehyde ferredoxin oxidoreductase
FPG73_RS01285	COG2165	general secretion pathway protein
FPG73_RS01295	COG2165	general secretion pathway protein
FPG73_RS01325	COG1459	type II secretion system
FPG73_RS01335	COG1187	pseudouridine synthase activity
FPG73_RS01340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FPG73_RS01345	COG0745	RESPONSE REGULATOR receiver
FPG73_RS01350	COG4191	Histidine kinase
FPG73_RS01355	COG0704	Plays a role in the regulation of phosphate uptake
FPG73_RS01370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FPG73_RS01380	COG0515	serine threonine protein kinase
FPG73_RS01380	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FPG73_RS01415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FPG73_RS01420	COG1028	Short-chain dehydrogenase reductase Sdr
FPG73_RS01435	COG0717	Belongs to the dCTP deaminase family
FPG73_RS01440	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FPG73_RS01445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FPG73_RS01450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FPG73_RS01470	COG0583	DNA-binding transcription factor activity
FPG73_RS01475	COG3546	catalase activity
FPG73_RS01480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FPG73_RS01480	COG0758	DNA mediated transformation
FPG73_RS01485	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FPG73_RS01500	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FPG73_RS01510	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
FPG73_RS01520	COG0442	prolyl-tRNA aminoacylation
FPG73_RS01525	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FPG73_RS01545	COG0303	'Molybdopterin
FPG73_RS01550	COG0513	Belongs to the DEAD box helicase family
FPG73_RS01560	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FPG73_RS01570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FPG73_RS01590	COG2070	2-Nitropropane dioxygenase
FPG73_RS01605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FPG73_RS01615	COG0018	arginyl-trna synthetase
FPG73_RS01620	COG1007	ATP synthesis coupled electron transport
FPG73_RS01625	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPG73_RS01630	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FPG73_RS01635	COG0713	ATP synthesis coupled electron transport
FPG73_RS01640	COG0839	Belongs to the complex I subunit 6 family
FPG73_RS01645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPG73_RS01650	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FPG73_RS01655	COG1034	ATP synthesis coupled electron transport
FPG73_RS01660	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FPG73_RS01665	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FPG73_RS01670	COG0649	NAD binding
FPG73_RS01675	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPG73_RS01680	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPG73_RS01685	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FPG73_RS01690	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FPG73_RS01700	COG4712	double-strand break repair protein
FPG73_RS01740	COG0135	phosphoribosylanthranilate isomerase activity
FPG73_RS01750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FPG73_RS01760	COG2720	vancomycin resistance protein
FPG73_RS01765	COG1126	abc transporter atp-binding protein
FPG73_RS01795	COG0277	FAD linked oxidase domain protein
FPG73_RS01810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FPG73_RS01815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FPG73_RS01830	COG0314	molybdopterin synthase activity
FPG73_RS01835	COG1420	regulation of RNA biosynthetic process
FPG73_RS01840	COG0347	Belongs to the P(II) protein family
FPG73_RS01845	COG0004	ammonium transporteR
FPG73_RS01855	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FPG73_RS01865	COG0123	including yeast histone deacetylase and acetoin utilization protein
FPG73_RS01880	COG1597	lipid kinase activity
FPG73_RS01890	COG0436	Aminotransferase
FPG73_RS01900	COG0475	glutathione-regulated potassium exporter activity
FPG73_RS01900	COG0569	domain protein
FPG73_RS01910	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FPG73_RS01920	COG0277	FAD linked oxidase domain protein
FPG73_RS01945	COG0667	Aldo Keto reductase
FPG73_RS01965	COG2199	diguanylate cyclase activity
FPG73_RS01975	COG1067	ATP-dependent peptidase activity
FPG73_RS01980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FPG73_RS01990	COG0745	RESPONSE REGULATOR receiver
FPG73_RS01995	COG2105	PFAM AIG2 family protein
FPG73_RS02000	COG0297	glycogen (starch) synthase activity
FPG73_RS02010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FPG73_RS02015	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FPG73_RS02030	COG0142	geranyltranstransferase activity
FPG73_RS02040	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FPG73_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
FPG73_RS02065	COG0492	ferredoxin-NADP+ reductase activity
FPG73_RS02075	COG0792	nuclease activity
FPG73_RS02080	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FPG73_RS02095	COG1175	transmembrane transport
FPG73_RS02100	COG0395	ABC-type sugar transport system, permease component
FPG73_RS02130	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FPG73_RS02135	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FPG73_RS02140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FPG73_RS02145	COG0805	protein transport
FPG73_RS02150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FPG73_RS02150	COG1605	Chorismate mutase
FPG73_RS02210	COG1063	alcohol dehydrogenase
FPG73_RS02240	COG2255	four-way junction helicase activity
FPG73_RS02245	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FPG73_RS02250	COG0564	pseudouridine synthase activity
FPG73_RS02265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FPG73_RS02270	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FPG73_RS02275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FPG73_RS02280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FPG73_RS02290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FPG73_RS02295	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FPG73_RS02300	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FPG73_RS02335	COG0778	Nitroreductase
FPG73_RS02350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FPG73_RS02355	COG0131	Imidazoleglycerol-phosphate dehydratase
FPG73_RS02360	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FPG73_RS02365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FPG73_RS02370	COG0516	GMP reductase activity
FPG73_RS02370	COG0517	IMP dehydrogenase activity
FPG73_RS02385	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FPG73_RS02390	COG1914	H( )-stimulated, divalent metal cation uptake system
FPG73_RS02405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FPG73_RS02420	COG2890	protein-(glutamine-N5) methyltransferase activity
FPG73_RS02430	COG0706	membrane insertase activity
FPG73_RS02435	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FPG73_RS02440	COG0594	ribonuclease P activity
FPG73_RS02445	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FPG73_RS02455	COG1022	Amp-dependent synthetase and ligase
FPG73_RS02480	COG1121	(ABC) transporter
FPG73_RS02485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FPG73_RS02490	COG1959	2 iron, 2 sulfur cluster binding
FPG73_RS02495	COG1104	cysteine desulfurase activity
FPG73_RS02500	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FPG73_RS02505	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FPG73_RS02520	COG1028	Short-chain dehydrogenase reductase Sdr
FPG73_RS02545	COG0492	ferredoxin-NADP+ reductase activity
FPG73_RS02555	COG1028	Short-chain dehydrogenase reductase Sdr
FPG73_RS02555	COG3321	synthase
FPG73_RS02555	COG0604	alcohol dehydrogenase
FPG73_RS02565	COG0601	transmembrane transport
FPG73_RS02570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPG73_RS02585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FPG73_RS02585	COG0617	tRNA 3'-terminal CCA addition
FPG73_RS02585	COG0517	IMP dehydrogenase activity
FPG73_RS02590	COG0123	including yeast histone deacetylase and acetoin utilization protein
FPG73_RS02595	COG2104	thiamine diphosphate biosynthetic process
FPG73_RS02600	COG0037	tRNA processing
FPG73_RS02615	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FPG73_RS02635	COG4176	ABC-type proline glycine betaine transport system permease component
FPG73_RS02640	COG4175	Glycine betaine
FPG73_RS02640	COG3448	diguanylate cyclase activity
FPG73_RS02645	COG0366	Alpha amylase catalytic
FPG73_RS02650	COG2226	methyltransferase
FPG73_RS02655	COG2226	methyltransferase
FPG73_RS02665	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FPG73_RS02675	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FPG73_RS02680	COG0460	homoserine dehydrogenase
FPG73_RS02690	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FPG73_RS02735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FPG73_RS02755	COG0247	lactate metabolic process
FPG73_RS02760	COG0277	FAD linked oxidase domain protein
FPG73_RS02765	COG0277	FAD linked oxidase domain protein
FPG73_RS02770	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FPG73_RS02775	COG1414	Transcriptional regulator
FPG73_RS02780	COG0789	Transcriptional regulator
FPG73_RS02790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPG73_RS02795	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FPG73_RS02830	COG0861	Integral membrane protein TerC family
FPG73_RS02835	COG2151	metal-sulfur cluster biosynthetic enzyme
FPG73_RS02840	COG0281	malic enzyme
FPG73_RS02855	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FPG73_RS02860	COG0509	glycine decarboxylation via glycine cleavage system
FPG73_RS02865	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FPG73_RS02870	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FPG73_RS02875	COG0196	riboflavin kinase activity
FPG73_RS02880	COG0494	nUDIX hydrolase
FPG73_RS02900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FPG73_RS02905	COG2813	Specifically methylates the guanine in position
FPG73_RS02910	COG0527	aspartate kinase activity
FPG73_RS02940	COG4956	integral membrane protein (PIN domain superfamily)
FPG73_RS02945	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FPG73_RS02950	COG0542	response to heat
FPG73_RS02955	COG0423	glycine-tRNA ligase activity
FPG73_RS02970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FPG73_RS02990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FPG73_RS02990	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FPG73_RS03000	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FPG73_RS03010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FPG73_RS03020	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FPG73_RS03025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FPG73_RS03030	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FPG73_RS03035	COG0114	fumarate hydratase activity
FPG73_RS03040	COG0183	Belongs to the thiolase family
FPG73_RS03055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FPG73_RS03060	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FPG73_RS03075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FPG73_RS03080	COG1254	Belongs to the acylphosphatase family
FPG73_RS03090	COG1063	alcohol dehydrogenase
FPG73_RS03100	COG2133	pyrroloquinoline quinone binding
FPG73_RS03110	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FPG73_RS03115	COG0154	amidase activity
FPG73_RS03140	COG0572	uridine kinase
FPG73_RS03145	COG3842	ATPase activity
FPG73_RS03160	COG4475	Protein of unknown function (DUF436)
FPG73_RS03180	COG1595	DNA-templated transcription, initiation
FPG73_RS03250	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FPG73_RS03255	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FPG73_RS03260	COG0803	Belongs to the bacterial solute-binding protein 9 family
FPG73_RS03275	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FPG73_RS03280	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FPG73_RS03285	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FPG73_RS03290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FPG73_RS03300	COG1028	Short-chain dehydrogenase reductase Sdr
FPG73_RS03305	COG0318	PFAM AMP-dependent synthetase and ligase
FPG73_RS03310	COG1012	belongs to the aldehyde dehydrogenase family
FPG73_RS03310	COG2030	dehydratase
FPG73_RS03315	COG1960	acyl-CoA dehydrogenase activity
FPG73_RS03330	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FPG73_RS03335	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FPG73_RS03340	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FPG73_RS03350	COG3870	Protein conserved in bacteria
FPG73_RS03355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FPG73_RS03375	COG0544	peptidyl-prolyl cis-trans isomerase activity
FPG73_RS03380	COG0740	serine-type endopeptidase activity
FPG73_RS03385	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FPG73_RS03390	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FPG73_RS03395	COG1410	methionine synthase
FPG73_RS03395	COG0646	methionine synthase
FPG73_RS03400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FPG73_RS03425	COG1692	metallophosphoesterase
FPG73_RS03430	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FPG73_RS03460	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FPG73_RS03465	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FPG73_RS03530	COG0438	transferase activity, transferring glycosyl groups
FPG73_RS03555	COG0529	Catalyzes the synthesis of activated sulfate
FPG73_RS03560	COG2046	Belongs to the sulfate adenylyltransferase family
FPG73_RS03570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPG73_RS03590	COG0489	protein tyrosine kinase activity
FPG73_RS03600	COG2264	protein methyltransferase activity
FPG73_RS03605	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FPG73_RS03635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FPG73_RS03635	COG0574	Belongs to the PEP-utilizing enzyme family
FPG73_RS03645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FPG73_RS03650	COG2046	Belongs to the sulfate adenylyltransferase family
FPG73_RS03655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FPG73_RS03655	COG1648	precorrin-2 dehydrogenase activity
FPG73_RS03660	COG0730	response to heat
FPG73_RS03665	COG0175	sulfate reduction
FPG73_RS03670	COG1648	precorrin-2 dehydrogenase activity
FPG73_RS03670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FPG73_RS03675	COG1587	Uroporphyrinogen-III synthase
FPG73_RS03680	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FPG73_RS03690	COG0352	thiamine-phosphate diphosphorylase activity
FPG73_RS03695	COG2104	thiamine diphosphate biosynthetic process
FPG73_RS03700	COG2022	thiamine diphosphate biosynthetic process
FPG73_RS03705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPG73_RS03705	COG2022	thiamine diphosphate biosynthetic process
FPG73_RS03710	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FPG73_RS03715	COG0477	Major facilitator Superfamily
FPG73_RS03720	COG0351	phosphomethylpyrimidine kinase
FPG73_RS03720	COG0352	thiamine-phosphate diphosphorylase activity
FPG73_RS03750	COG1175	transmembrane transport
FPG73_RS03760	COG1940	carbohydrate kinase activity
FPG73_RS03765	COG0183	Belongs to the thiolase family
FPG73_RS03780	COG1028	Short-chain dehydrogenase reductase Sdr
FPG73_RS03800	COG0559	Belongs to the binding-protein-dependent transport system permease family
FPG73_RS03815	COG2030	dehydratase
FPG73_RS03825	COG0596	Alpha beta hydrolase
FPG73_RS03830	COG0318	PFAM AMP-dependent synthetase and ligase
FPG73_RS03845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FPG73_RS03845	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FPG73_RS03855	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FPG73_RS03865	COG0195	Participates in both transcription termination and antitermination
FPG73_RS03870	COG0779	Required for maturation of 30S ribosomal subunits
FPG73_RS03880	COG0739	heme binding
FPG73_RS03885	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FPG73_RS03890	COG0640	Transcriptional regulator
FPG73_RS03895	COG2217	Heavy metal translocating P-type atpase
FPG73_RS03900	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FPG73_RS03905	COG0017	Asparaginyl-tRNA synthetase
FPG73_RS03910	COG0561	phosphatase activity
FPG73_RS03915	COG0384	phenazine biosynthesis protein PhzF
FPG73_RS03925	COG0124	histidyl-tRNA synthetase
FPG73_RS03935	COG3842	ATPase activity
FPG73_RS03955	COG1573	uracil-dna glycosylase
FPG73_RS03975	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FPG73_RS03980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FPG73_RS03980	COG0519	Catalyzes the synthesis of GMP from XMP
FPG73_RS03990	COG1316	TRANSCRIPTIONal
FPG73_RS04000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FPG73_RS04045	COG0295	cytidine deaminase activity
FPG73_RS04065	COG1760	l-serine dehydratase
FPG73_RS04075	COG0481	GTPase activity
FPG73_RS04085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FPG73_RS04090	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FPG73_RS04100	COG1028	Short-chain dehydrogenase reductase Sdr
FPG73_RS04125	COG0405	Gamma-glutamyltransferase
FPG73_RS04135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FPG73_RS04140	COG2873	o-acetylhomoserine
FPG73_RS04155	COG1063	alcohol dehydrogenase
FPG73_RS04165	COG3191	aminopeptidase activity
FPG73_RS04170	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FPG73_RS04180	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPG73_RS04185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPG73_RS04190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FPG73_RS04195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPG73_RS04205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FPG73_RS04220	COG0167	dihydroorotate dehydrogenase activity
FPG73_RS04255	COG0730	response to heat
FPG73_RS04260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FPG73_RS04280	COG1960	acyl-CoA dehydrogenase activity
FPG73_RS04285	COG0456	acetyltransferase
FPG73_RS04295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FPG73_RS04300	COG0009	L-threonylcarbamoyladenylate synthase
FPG73_RS04305	COG1459	type II secretion system
FPG73_RS04320	COG0277	FAD linked oxidase domain protein
FPG73_RS04330	COG0287	Prephenate dehydrogenase
FPG73_RS04335	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FPG73_RS04340	COG2514	catechol 2,3-dioxygenase activity
FPG73_RS04345	COG2353	YceI-like domain
FPG73_RS04350	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FPG73_RS04355	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FPG73_RS04375	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FPG73_RS04380	COG0179	Fumarylacetoacetate (FAA) hydrolase
FPG73_RS04390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FPG73_RS04395	COG0151	Belongs to the GarS family
FPG73_RS04400	COG2176	DNA-directed DNA polymerase activity
FPG73_RS04400	COG5002	protein histidine kinase activity
FPG73_RS04430	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FPG73_RS04440	COG0217	transcriptional regulatory protein
FPG73_RS04445	COG4651	solute:proton antiporter activity
FPG73_RS04445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FPG73_RS04450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FPG73_RS04455	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FPG73_RS04460	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FPG73_RS04465	COG1674	ftsk spoiiie
FPG73_RS04480	COG0517	IMP dehydrogenase activity
FPG73_RS04495	COG3620	sequence-specific DNA binding
FPG73_RS04495	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FPG73_RS04495	COG0617	tRNA 3'-terminal CCA addition
FPG73_RS04505	COG1994	Peptidase M50
FPG73_RS04510	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FPG73_RS04520	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FPG73_RS04535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FPG73_RS04540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPG73_RS04545	COG2719	SpoVR family
FPG73_RS04550	COG2718	Belongs to the UPF0229 family
FPG73_RS04555	COG2766	serine protein kinase
FPG73_RS04580	COG2137	regulation of response to DNA damage stimulus
FPG73_RS04590	COG2359	stage V sporulation protein S
FPG73_RS04595	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FPG73_RS04600	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FPG73_RS04610	COG0463	Glycosyl transferase, family 2
FPG73_RS04615	COG0750	zinc metalloprotease
FPG73_RS04620	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FPG73_RS04625	COG0575	Belongs to the CDS family
FPG73_RS04630	COG0233	cytoplasmic translational termination
FPG73_RS04635	COG0528	UMP kinase activity
FPG73_RS04640	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FPG73_RS04645	COG0052	Belongs to the universal ribosomal protein uS2 family
FPG73_RS04655	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FPG73_RS04660	COG0494	nUDIX hydrolase
FPG73_RS04680	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FPG73_RS04690	COG0402	S-adenosylhomocysteine deaminase activity
FPG73_RS04700	COG4948	Mandelate Racemase Muconate Lactonizing
FPG73_RS04705	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FPG73_RS04710	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FPG73_RS04715	COG1811	Na channel or pump
FPG73_RS04720	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FPG73_RS04720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPG73_RS04735	COG1215	transferase activity, transferring glycosyl groups
FPG73_RS04745	COG1215	transferase activity, transferring glycosyl groups
FPG73_RS04755	COG0438	transferase activity, transferring glycosyl groups
FPG73_RS04760	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FPG73_RS04775	COG1024	Enoyl-CoA hydratase
FPG73_RS04775	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPG73_RS04780	COG0183	Belongs to the thiolase family
FPG73_RS04785	COG1960	acyl-CoA dehydrogenase activity
FPG73_RS04790	COG0215	cysteine-tRNA ligase activity
FPG73_RS04795	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FPG73_RS04825	COG1196	nuclear chromosome segregation
FPG73_RS04840	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FPG73_RS04845	COG3153	acetyltransferase
FPG73_RS04845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FPG73_RS04850	COG1268	BioY protein
FPG73_RS04860	COG0126	phosphoglycerate kinase activity
FPG73_RS04865	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FPG73_RS04870	COG0824	Thioesterase
FPG73_RS04880	COG0557	exoribonuclease II activity
FPG73_RS04885	COG1355	regulation of microtubule-based process
FPG73_RS04890	COG0617	tRNA 3'-terminal CCA addition
FPG73_RS04890	COG1353	crispr-associated protein
FPG73_RS04895	COG0237	dephospho-CoA kinase activity
FPG73_RS04900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FPG73_RS04910	COG0742	ribosomal rna small subunit methyltransferase
FPG73_RS04915	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FPG73_RS04920	COG0138	bifunctional purine biosynthesis protein purh
FPG73_RS04925	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FPG73_RS04940	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FPG73_RS04995	COG0149	triose-phosphate isomerase activity
FPG73_RS05000	COG3239	Fatty acid desaturase
FPG73_RS05010	COG1490	D-aminoacyl-tRNA deacylase activity
FPG73_RS05015	COG1307	EDD domain protein, DegV family
FPG73_RS05020	COG1307	EDD domain protein, DegV family
FPG73_RS05025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FPG73_RS05030	COG1510	regulation of RNA biosynthetic process
FPG73_RS05050	COG1136	(ABC) transporter
FPG73_RS05065	COG3769	mannosylglycerate metabolic process
FPG73_RS05075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FPG73_RS05085	COG1012	belongs to the aldehyde dehydrogenase family
FPG73_RS05090	COG2368	4-hydroxyphenylacetate
FPG73_RS05095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FPG73_RS05125	COG2050	protein possibly involved in aromatic compounds catabolism
FPG73_RS05130	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FPG73_RS05140	COG2030	dehydratase
FPG73_RS05140	COG1012	belongs to the aldehyde dehydrogenase family
FPG73_RS05160	COG3396	Phenylacetate-CoA oxygenase
FPG73_RS05170	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FPG73_RS05180	COG0395	ABC-type sugar transport system, permease component
FPG73_RS05200	COG1980	fructose-bisphosphate aldolase activity
FPG73_RS05205	COG1733	regulation of RNA biosynthetic process
FPG73_RS05210	COG2193	ferroxidase activity
FPG73_RS05215	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FPG73_RS05220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FPG73_RS05230	COG1331	Highly conserved protein containing a thioredoxin domain
FPG73_RS05235	COG0183	Belongs to the thiolase family
FPG73_RS05240	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FPG73_RS05245	COG0477	Major facilitator Superfamily
FPG73_RS05290	COG1012	belongs to the aldehyde dehydrogenase family
FPG73_RS05300	COG0248	Ppx GppA phosphatase
FPG73_RS05305	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FPG73_RS05310	COG0210	DNA helicase
FPG73_RS05325	COG1309	transcriptional regulator
FPG73_RS05330	COG1131	(ABC) transporter
FPG73_RS05335	COG0842	Transport permease protein
FPG73_RS05360	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPG73_RS05385	COG0582	viral genome integration into host DNA
FPG73_RS05395	COG2897	thiosulfate sulfurtransferase activity
FPG73_RS05400	COG1760	l-serine dehydratase
FPG73_RS05405	COG2197	response regulator
FPG73_RS05410	COG0335	large ribosomal subunit rRNA binding
FPG73_RS05415	COG0336	Belongs to the RNA methyltransferase TrmD family
FPG73_RS05420	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FPG73_RS05425	COG1837	Belongs to the UPF0109 family
FPG73_RS05430	COG0228	four-way junction DNA binding
FPG73_RS05445	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPG73_RS05450	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPG73_RS05450	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPG73_RS05455	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FPG73_RS05465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FPG73_RS05475	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FPG73_RS05480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FPG73_RS05485	COG1702	phosphate starvation-inducible protein PhoH
FPG73_RS05495	COG4864	UPF0365 protein
FPG73_RS05505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FPG73_RS05515	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPG73_RS05515	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FPG73_RS05520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FPG73_RS05530	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FPG73_RS05535	COG1397	ADP-ribosylglycohydrolase
FPG73_RS05540	COG2239	Acts as a magnesium transporter
FPG73_RS05545	COG2304	oxidoreductase activity
FPG73_RS05550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FPG73_RS05550	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FPG73_RS05560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FPG73_RS05560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FPG73_RS05565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FPG73_RS05570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FPG73_RS05575	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FPG73_RS05580	COG0006	proline dipeptidase activity
FPG73_RS05590	COG0739	heme binding
FPG73_RS05600	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FPG73_RS05605	COG0254	rRNA binding
FPG73_RS05620	COG2001	Belongs to the MraZ family
FPG73_RS05625	COG0275	rRNA processing
FPG73_RS05640	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FPG73_RS05650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPG73_RS05655	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FPG73_RS05660	COG0772	Belongs to the SEDS family
FPG73_RS05665	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FPG73_RS05670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FPG73_RS05675	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FPG73_RS05695	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FPG73_RS05710	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
FPG73_RS05720	COG0159	tryptophan synthase activity
FPG73_RS05725	COG0133	tryptophan synthase activity
FPG73_RS05730	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FPG73_RS05735	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FPG73_RS05740	COG1744	ABC transporter substrate-binding protein PnrA-like
FPG73_RS05745	COG3845	ABC transporter
FPG73_RS05795	COG0438	transferase activity, transferring glycosyl groups
FPG73_RS05800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FPG73_RS05810	COG0039	L-malate dehydrogenase activity
FPG73_RS05815	COG2819	hydrolase of the alpha beta superfamily
FPG73_RS05820	COG0861	Integral membrane protein TerC family
FPG73_RS05830	COG2181	nitrate reductase activity
FPG73_RS05830	COG0247	lactate metabolic process
FPG73_RS05840	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
FPG73_RS05845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FPG73_RS05850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FPG73_RS05860	COG0439	Biotin carboxylase
FPG73_RS05865	COG0511	ligase activity, forming carbon-carbon bonds
FPG73_RS05870	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FPG73_RS05885	COG0010	Belongs to the arginase family
FPG73_RS05900	COG1100	Small GTP-binding protein
FPG73_RS05910	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FPG73_RS05915	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FPG73_RS05925	COG2814	Major facilitator Superfamily
FPG73_RS05930	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FPG73_RS05935	COG1185	polyribonucleotide nucleotidyltransferase activity
FPG73_RS05940	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FPG73_RS05945	COG0589	response to stress
FPG73_RS05960	COG3335	DDE superfamily endonuclease
FPG73_RS05970	COG0617	tRNA 3'-terminal CCA addition
FPG73_RS05970	COG0517	IMP dehydrogenase activity
FPG73_RS05970	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FPG73_RS05975	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FPG73_RS05980	COG0745	RESPONSE REGULATOR receiver
FPG73_RS05985	COG5002	protein histidine kinase activity
FPG73_RS05990	COG1960	acyl-CoA dehydrogenase activity
FPG73_RS05995	COG2086	electron transfer activity
FPG73_RS06000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FPG73_RS06010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FPG73_RS06015	COG1573	uracil-dna glycosylase
FPG73_RS06020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FPG73_RS06020	COG1796	DNA polymerase
FPG73_RS06040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPG73_RS06050	COG1011	Hydrolase
FPG73_RS06070	COG2873	o-acetylhomoserine
FPG73_RS06075	COG2358	TRAP transporter, solute receptor (TAXI family
FPG73_RS06085	COG1126	abc transporter atp-binding protein
FPG73_RS06100	COG0134	indole-3-glycerol-phosphate synthase activity
FPG73_RS06105	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FPG73_RS06115	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FPG73_RS06130	COG0765	amino acid transport
FPG73_RS06135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FPG73_RS06145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FPG73_RS06150	COG0569	domain protein
FPG73_RS06155	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FPG73_RS06160	COG1426	Protein conserved in bacteria
FPG73_RS06165	COG2313	pseudouridylate synthase activity
FPG73_RS06175	COG3001	Fructosamine kinase
FPG73_RS06180	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FPG73_RS06190	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FPG73_RS06215	COG0012	GTP binding
FPG73_RS06220	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FPG73_RS06230	COG0424	maF-like protein
FPG73_RS06245	COG0768	penicillin binding
FPG73_RS06250	COG0850	regulation of cytokinetic process
FPG73_RS06255	COG2322	membrane
FPG73_RS06275	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FPG73_RS06280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FPG73_RS06290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FPG73_RS06310	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FPG73_RS06320	COG1131	(ABC) transporter
FPG73_RS06335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FPG73_RS06350	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FPG73_RS06355	COG0440	acetolactate synthase activity
FPG73_RS06360	COG0028	Belongs to the TPP enzyme family
FPG73_RS06370	COG0492	ferredoxin-NADP+ reductase activity
FPG73_RS06375	COG4970	Tfp pilus assembly protein FimT
FPG73_RS06380	COG4970	Tfp pilus assembly protein FimT
FPG73_RS06385	COG2165	general secretion pathway protein
FPG73_RS06390	COG4966	pilus assembly protein PilW
FPG73_RS06400	COG2165	general secretion pathway protein
FPG73_RS06415	COG4636	protein conserved in cyanobacteria
FPG73_RS06450	COG0180	Tryptophanyl-tRNA synthetase
FPG73_RS06455	COG0544	peptidyl-prolyl cis-trans isomerase activity
FPG73_RS06460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FPG73_RS06465	COG0066	3-isopropylmalate dehydratase activity
FPG73_RS06470	COG0473	3-isopropylmalate dehydrogenase activity
FPG73_RS06485	COG0300	oxidoreductase activity
FPG73_RS06490	COG0129	dihydroxy-acid dehydratase activity
FPG73_RS06500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FPG73_RS06505	COG1177	transmembrane transport
FPG73_RS06510	COG1176	ABC-type spermidine putrescine transport system, permease component I
FPG73_RS06515	COG3842	ATPase activity
FPG73_RS06520	COG0772	Belongs to the SEDS family
FPG73_RS06525	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FPG73_RS06530	COG2894	cell division
FPG73_RS06535	COG1733	regulation of RNA biosynthetic process
FPG73_RS06545	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPG73_RS06545	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FPG73_RS06555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FPG73_RS06560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FPG73_RS06565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FPG73_RS06570	COG0653	protein targeting
FPG73_RS06575	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FPG73_RS06595	COG0393	Putative heavy-metal-binding
FPG73_RS06600	COG1111	helicase
FPG73_RS06600	COG1205	dead DEAH box helicase
FPG73_RS06615	COG0358	DNA primase activity
FPG73_RS06630	COG1250	3-hydroxyacyl-CoA dehydrogenase
FPG73_RS06635	COG0697	spore germination
FPG73_RS06640	COG0612	Peptidase, M16
FPG73_RS06645	COG0612	Peptidase, M16
FPG73_RS06650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FPG73_RS06665	COG1394	ATPase activity, coupled to movement of substances
FPG73_RS06670	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FPG73_RS06675	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FPG73_RS06680	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
FPG73_RS06685	COG1527	subunit (C
FPG73_RS06690	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
FPG73_RS06700	COG1269	ATP hydrolysis coupled proton transport
FPG73_RS06735	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FPG73_RS06745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FPG73_RS06760	COG0419	ATPase involved in DNA repair
FPG73_RS06765	COG0420	3'-5' exonuclease activity
FPG73_RS06785	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FPG73_RS06790	COG2884	Cell division ATP-binding protein ftsE
FPG73_RS06795	COG0793	Belongs to the peptidase S41A family
FPG73_RS06800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPG73_RS06800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FPG73_RS06805	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FPG73_RS06810	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FPG73_RS06820	COG1079	Belongs to the binding-protein-dependent transport system permease family
FPG73_RS06825	COG4603	Belongs to the binding-protein-dependent transport system permease family
FPG73_RS06830	COG1129	ABC transporter
FPG73_RS06835	COG0746	molybdenum cofactor guanylyltransferase activity
FPG73_RS06850	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FPG73_RS06870	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FPG73_RS06875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FPG73_RS06880	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FPG73_RS06890	COG0517	IMP dehydrogenase activity
FPG73_RS06890	COG1994	Peptidase M50
FPG73_RS06895	COG2358	TRAP transporter, solute receptor (TAXI family
FPG73_RS06905	COG2358	TRAP transporter, solute receptor (TAXI family
FPG73_RS06920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FPG73_RS06925	COG0788	formyltetrahydrofolate deformylase activity
FPG73_RS06930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FPG73_RS06935	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FPG73_RS06940	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FPG73_RS06960	COG0737	Belongs to the 5'-nucleotidase family
FPG73_RS06965	COG0174	glutamine synthetase
FPG73_RS06975	COG0559	Belongs to the binding-protein-dependent transport system permease family
FPG73_RS06995	COG0747	negative chemotaxis
FPG73_RS07000	COG0601	transmembrane transport
FPG73_RS07005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPG73_RS07015	COG0285	dihydrofolate synthase activity
FPG73_RS07020	COG1132	(ABC) transporter
FPG73_RS07025	COG1132	(ABC) transporter
FPG73_RS07030	COG0372	Belongs to the citrate synthase family
FPG73_RS07035	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FPG73_RS07040	COG1482	cell wall glycoprotein biosynthetic process
FPG73_RS07050	COG1515	deoxyribonuclease V activity
FPG73_RS07060	COG0776	regulation of translation
FPG73_RS07075	COG2197	response regulator
FPG73_RS07080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FPG73_RS07085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FPG73_RS07090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FPG73_RS07095	COG1324	tolerance protein
FPG73_RS07100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPG73_RS07120	COG2205	protein histidine kinase activity
FPG73_RS07135	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FPG73_RS07170	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FPG73_RS07175	COG0247	lactate metabolic process
FPG73_RS07180	COG1139	Iron-sulfur cluster binding protein
FPG73_RS07185	COG1556	Lactate utilization protein
FPG73_RS07195	COG1752	Esterase of the alpha-beta hydrolase superfamily
FPG73_RS07200	COG2815	serine threonine protein kinase
FPG73_RS07200	COG0515	serine threonine protein kinase
FPG73_RS07210	COG0860	N-Acetylmuramoyl-L-alanine amidase
FPG73_RS07220	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FPG73_RS07255	COG0473	3-isopropylmalate dehydrogenase activity
FPG73_RS07280	COG1450	Type ii and iii secretion system protein
FPG73_RS07285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FPG73_RS07290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FPG73_RS07295	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FPG73_RS07300	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FPG73_RS07300	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FPG73_RS07305	COG0736	holo-[acyl-carrier-protein] synthase activity
FPG73_RS07320	COG1160	GTP binding
FPG73_RS07325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FPG73_RS07330	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FPG73_RS07330	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FPG73_RS07335	COG2814	Major facilitator Superfamily
FPG73_RS07340	COG0083	homoserine kinase activity
FPG73_RS07355	COG0268	Binds directly to 16S ribosomal RNA
FPG73_RS07365	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FPG73_RS07370	COG0723	plastoquinol--plastocyanin reductase activity
FPG73_RS07380	COG3088	subunit of a heme lyase
FPG73_RS07380	COG4235	cytochrome complex assembly
FPG73_RS07385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FPG73_RS07390	COG1138	Cytochrome C-type biogenesis protein
FPG73_RS07395	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FPG73_RS07400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FPG73_RS07405	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FPG73_RS07410	COG4133	protoheme IX ABC transporter activity
FPG73_RS07415	COG0785	Cytochrome C biogenesis protein
FPG73_RS07420	COG3258	Cytochrome c
FPG73_RS07430	COG0446	pyridine nucleotide-disulphide oxidoreductase
FPG73_RS07445	COG3258	Cytochrome c
FPG73_RS07450	COG2010	Cytochrome c
FPG73_RS07455	COG0737	Belongs to the 5'-nucleotidase family
FPG73_RS07460	COG2010	Cytochrome c
FPG73_RS07465	COG3258	Cytochrome c
FPG73_RS07485	COG2010	Cytochrome c
FPG73_RS07490	COG3842	ATPase activity
FPG73_RS07520	COG0318	PFAM AMP-dependent synthetase and ligase
FPG73_RS07525	COG3360	Dodecin
FPG73_RS07540	COG1024	Enoyl-CoA hydratase
FPG73_RS07545	COG0813	purine-nucleoside phosphorylase activity
FPG73_RS07550	COG1136	(ABC) transporter
FPG73_RS07555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPG73_RS07560	COG2045	Belongs to the ComB family
FPG73_RS07570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FPG73_RS07580	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FPG73_RS07585	COG0107	imidazoleglycerol-phosphate synthase activity
FPG73_RS07590	COG0140	phosphoribosyl-ATP diphosphatase activity
FPG73_RS07590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FPG73_RS07595	COG1494	fructose-1,6-bisphosphatase
FPG73_RS07600	COG0686	Belongs to the AlaDH PNT family
FPG73_RS07605	COG0427	acetyl-CoA hydrolase
FPG73_RS07615	COG0084	hydrolase, TatD family'
FPG73_RS07620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FPG73_RS07630	COG0017	Asparaginyl-tRNA synthetase
FPG73_RS07645	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FPG73_RS07660	COG2009	succinate dehydrogenase
FPG73_RS07665	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FPG73_RS07695	COG0318	PFAM AMP-dependent synthetase and ligase
FPG73_RS07700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FPG73_RS07705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FPG73_RS07710	COG0504	CTP synthase activity
FPG73_RS07735	COG0067	glutamate synthase
FPG73_RS07735	COG0070	glutamate synthase
FPG73_RS07735	COG0069	glutamate synthase activity
FPG73_RS07785	COG0840	transmembrane signaling receptor activity
FPG73_RS07790	COG0305	Participates in initiation and elongation during chromosome replication
FPG73_RS07800	COG0475	glutathione-regulated potassium exporter activity
FPG73_RS07805	COG0517	IMP dehydrogenase activity
FPG73_RS07805	COG0617	tRNA 3'-terminal CCA addition
FPG73_RS07805	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FPG73_RS07820	COG0475	glutathione-regulated potassium exporter activity
FPG73_RS07825	COG0490	domain, Protein
FPG73_RS07845	COG3118	belongs to the thioredoxin family
FPG73_RS07885	COG0542	response to heat
FPG73_RS07890	COG0789	Transcriptional regulator
FPG73_RS07895	COG0484	heat shock protein binding
FPG73_RS07900	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FPG73_RS07905	COG0443	Heat shock 70 kDa protein
FPG73_RS07910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FPG73_RS07915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FPG73_RS07920	COG0616	signal peptide processing
FPG73_RS07935	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
FPG73_RS07940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FPG73_RS07945	COG0714	Associated with various cellular activities
FPG73_RS07950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FPG73_RS07950	COG0574	Belongs to the PEP-utilizing enzyme family
FPG73_RS07965	COG3850	Histidine kinase
FPG73_RS07965	COG5002	protein histidine kinase activity
FPG73_RS07990	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FPG73_RS08005	COG1011	Hydrolase
FPG73_RS08030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FPG73_RS08045	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FPG73_RS08055	COG0047	phosphoribosylformylglycinamidine synthase activity
FPG73_RS08065	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FPG73_RS08070	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FPG73_RS08075	COG0116	Belongs to the methyltransferase superfamily
FPG73_RS08090	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FPG73_RS08095	COG0497	DNA recombination
FPG73_RS08105	COG0604	alcohol dehydrogenase
FPG73_RS08125	COG0585	pseudouridine synthase activity
FPG73_RS08150	COG1595	DNA-templated transcription, initiation
FPG73_RS08155	COG0557	exoribonuclease II activity
FPG73_RS08160	COG0538	isocitrate dehydrogenase activity
FPG73_RS08165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPG73_RS08165	COG2022	thiamine diphosphate biosynthetic process
FPG73_RS08175	COG0582	viral genome integration into host DNA
FPG73_RS08220	COG0037	tRNA processing
FPG73_RS08220	COG0590	tRNA wobble adenosine to inosine editing
FPG73_RS08245	COG2050	protein possibly involved in aromatic compounds catabolism
FPG73_RS08255	COG0322	excinuclease ABC activity
FPG73_RS08260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FPG73_RS08265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FPG73_RS08270	COG1854	S-ribosylhomocysteine lyase activity
FPG73_RS08285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FPG73_RS08285	COG0519	Catalyzes the synthesis of GMP from XMP
FPG73_RS08290	COG4636	protein conserved in cyanobacteria
FPG73_RS08295	COG4274	PFAM GYD family protein
FPG73_RS08300	COG0346	lactoylglutathione lyase activity
FPG73_RS08315	COG0328	RNA-DNA hybrid ribonuclease activity
FPG73_RS08320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FPG73_RS08325	COG2095	MarC family integral membrane protein
FPG73_RS08330	COG1438	arginine binding
FPG73_RS08335	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FPG73_RS08340	COG1758	RNA polymerase activity
FPG73_RS08345	COG0194	GDP metabolic process
FPG73_RS08355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FPG73_RS08360	COG2385	sporulation resulting in formation of a cellular spore
FPG73_RS08365	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FPG73_RS08375	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
FPG73_RS08415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FPG73_RS08420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FPG73_RS08425	COG1012	belongs to the aldehyde dehydrogenase family
FPG73_RS08430	COG0506	proline dehydrogenase activity
FPG73_RS08445	COG0156	8-amino-7-oxononanoate synthase activity
FPG73_RS08450	COG0827	DNA restriction-modification system
FPG73_RS08450	COG0732	type I restriction modification DNA specificity domain
FPG73_RS08460	COG0187	DNA topoisomerase II activity
FPG73_RS08465	COG1181	Belongs to the D-alanine--D-alanine ligase family
FPG73_RS08470	COG0193	aminoacyl-tRNA hydrolase activity
FPG73_RS08475	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FPG73_RS08500	COG0515	serine threonine protein kinase
FPG73_RS08500	COG2815	serine threonine protein kinase
FPG73_RS08505	COG0631	protein serine/threonine phosphatase activity
FPG73_RS08515	COG2814	Major facilitator Superfamily
FPG73_RS08520	COG0113	porphobilinogen synthase activity
FPG73_RS08525	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FPG73_RS08530	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FPG73_RS08555	COG0823	Involved in the tonB-independent uptake of proteins
FPG73_RS08555	COG1506	peptidase
FPG73_RS08555	COG4946	Tricorn protease homolog
FPG73_RS08560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FPG73_RS08565	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FPG73_RS08585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FPG73_RS08590	COG1011	Hydrolase
FPG73_RS08615	COG0537	adenosine 5'-monophosphoramidase activity
FPG73_RS08620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FPG73_RS08625	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FPG73_RS08630	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FPG73_RS08635	COG0071	Belongs to the small heat shock protein (HSP20) family
FPG73_RS08640	COG2897	thiosulfate sulfurtransferase activity
FPG73_RS08645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FPG73_RS08655	COG1764	response to oxidative stress
FPG73_RS08680	COG3842	ATPase activity
FPG73_RS08685	COG0101	tRNA pseudouridine synthase activity
FPG73_RS08690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FPG73_RS08695	COG0601	transmembrane transport
FPG73_RS08715	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FPG73_RS08730	COG1166	arginine decarboxylase activity
FPG73_RS08735	COG3706	GGDEF domain
FPG73_RS08740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FPG73_RS08745	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FPG73_RS08750	COG1611	Belongs to the LOG family
FPG73_RS08755	COG1193	negative regulation of DNA recombination
FPG73_RS08760	COG0366	Alpha amylase catalytic
FPG73_RS08795	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FPG73_RS08800	COG0142	geranyltranstransferase activity
FPG73_RS08820	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FPG73_RS08850	COG0203	ribosomal protein L17
FPG73_RS08855	COG0202	RNA polymerase activity
FPG73_RS08860	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FPG73_RS08865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FPG73_RS08870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FPG73_RS08880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FPG73_RS08890	COG0563	adenylate kinase activity
FPG73_RS08895	COG0201	protein transport
FPG73_RS08920	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FPG73_RS08925	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FPG73_RS08930	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FPG73_RS08955	COG0255	Belongs to the universal ribosomal protein uL29 family
FPG73_RS08960	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FPG73_RS08965	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FPG73_RS08975	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FPG73_RS08980	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FPG73_RS08985	COG0089	rRNA binding
FPG73_RS08990	COG0088	Forms part of the polypeptide exit tunnel
FPG73_RS09000	COG0051	transcription antitermination factor activity, RNA binding
FPG73_RS09005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FPG73_RS09010	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FPG73_RS09015	COG0049	tRNA binding
FPG73_RS09030	COG0442	prolyl-tRNA aminoacylation
FPG73_RS09040	COG1115	amino acid carrier protein
FPG73_RS09060	COG1489	DNA binding
FPG73_RS09085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FPG73_RS09105	COG0432	Pfam Uncharacterised protein family UPF0047
FPG73_RS09110	COG3253	May function as heme-dependent peroxidase
FPG73_RS09115	COG0668	transmembrane transport
FPG73_RS09125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FPG73_RS09130	COG2217	Heavy metal translocating P-type atpase
FPG73_RS09150	COG0745	RESPONSE REGULATOR receiver
FPG73_RS09155	COG2205	protein histidine kinase activity
FPG73_RS09180	COG2226	methyltransferase
FPG73_RS09200	COG2132	Multicopper oxidase
FPG73_RS09210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FPG73_RS09215	COG0822	iron-sulfur transferase activity
FPG73_RS09235	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FPG73_RS09245	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FPG73_RS09250	COG0284	orotidine-5'-phosphate decarboxylase activity
FPG73_RS09260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FPG73_RS09270	COG0416	fatty acid biosynthetic process
FPG73_RS09275	COG3118	belongs to the thioredoxin family
FPG73_RS09280	COG1185	polyribonucleotide nucleotidyltransferase activity
FPG73_RS09285	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FPG73_RS09295	COG0438	transferase activity, transferring glycosyl groups
FPG73_RS09315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FPG73_RS09320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FPG73_RS09325	COG3706	GGDEF domain
FPG73_RS09360	COG0437	4 iron, 4 sulfur cluster binding
FPG73_RS09375	COG0825	malonyl-CoA metabolic process
FPG73_RS09380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FPG73_RS09415	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FPG73_RS09440	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FPG73_RS09445	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FPG73_RS09450	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FPG73_RS09455	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FPG73_RS09475	COG4974	Belongs to the 'phage' integrase family
FPG73_RS09565	COG0315	cyclic pyranopterin monophosphate synthase activity
FPG73_RS09570	COG2860	membrane
FPG73_RS09575	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FPG73_RS09590	COG0477	Major facilitator Superfamily
FPG73_RS09595	COG1694	Mazg nucleotide pyrophosphohydrolase
FPG73_RS09600	COG1803	Methylglyoxal synthase
FPG73_RS09610	COG0301	tRNA thio-modification
FPG73_RS09615	COG0154	amidase activity
FPG73_RS09620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FPG73_RS09640	COG2154	pterin-4-alpha-carbinolamine dehydratase
FPG73_RS09645	COG1607	acyl-coa hydrolase
FPG73_RS09655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FPG73_RS09660	COG4149	molybdate abc transporter
FPG73_RS09665	COG1840	ABC-type Fe3 transport system, periplasmic component
FPG73_RS09680	COG0235	Class ii aldolase
FPG73_RS09685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FPG73_RS09690	COG0085	RNA polymerase activity
FPG73_RS09700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FPG73_RS09705	COG1077	Cell shape determining protein MreB Mrl
FPG73_RS09710	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FPG73_RS09710	COG1418	mRNA catabolic process
FPG73_RS09715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FPG73_RS09720	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FPG73_RS09725	COG1546	Belongs to the CinA family
FPG73_RS09725	COG1058	Belongs to the CinA family
FPG73_RS09730	COG0354	folic acid binding
FPG73_RS09745	COG4948	Mandelate Racemase Muconate Lactonizing
FPG73_RS09760	COG1175	transmembrane transport
FPG73_RS09770	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FPG73_RS09780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FPG73_RS09790	COG1136	(ABC) transporter
FPG73_RS09790	COG0577	efflux transmembrane transporter activity
FPG73_RS09795	COG4181	ATPase activity
FPG73_RS09800	COG0446	pyridine nucleotide-disulphide oxidoreductase
FPG73_RS09815	COG0396	ATPase activity
FPG73_RS09820	COG0719	Fe-S assembly protein
FPG73_RS09825	COG0719	Fe-S assembly protein
FPG73_RS09830	COG2146	nitrite reductase [NAD(P)H] activity
FPG73_RS09840	COG0512	Glutamine amidotransferase of anthranilate synthase
FPG73_RS09845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FPG73_RS09880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FPG73_RS09885	COG2226	methyltransferase
FPG73_RS09890	COG4603	Belongs to the binding-protein-dependent transport system permease family
FPG73_RS09895	COG1079	Belongs to the binding-protein-dependent transport system permease family
FPG73_RS09910	COG1774	PSP1 C-terminal conserved region
FPG73_RS09915	COG0470	DNA polymerase III
FPG73_RS09950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FPG73_RS09955	COG0302	gtp cyclohydrolase
FPG73_RS09980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FPG73_RS09990	COG0395	ABC-type sugar transport system, permease component
FPG73_RS10005	COG1131	(ABC) transporter
FPG73_RS10025	COG0556	nucleotide-excision repair
FPG73_RS10030	COG0497	DNA recombination
FPG73_RS10035	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FPG73_RS10045	COG0445	tRNA wobble uridine modification
FPG73_RS10065	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FPG73_RS10065	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FPG73_RS10070	COG1543	Belongs to the glycosyl hydrolase 57 family
FPG73_RS10075	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FPG73_RS10080	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FPG73_RS10085	COG0189	ligase activity
FPG73_RS10100	COG0066	3-isopropylmalate dehydratase activity
FPG73_RS10105	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FPG73_RS10120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FPG73_RS10125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FPG73_RS10130	COG1960	acyl-CoA dehydrogenase activity
FPG73_RS10135	COG0163	prenyltransferase activity
FPG73_RS10180	COG2096	Adenosyltransferase
FPG73_RS10205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FPG73_RS10210	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FPG73_RS10220	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FPG73_RS10225	COG0723	plastoquinol--plastocyanin reductase activity
FPG73_RS10250	COG1653	transport
FPG73_RS10255	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FPG73_RS10260	COG1960	acyl-CoA dehydrogenase activity
FPG73_RS10270	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FPG73_RS10305	COG1131	(ABC) transporter
FPG73_RS10330	COG3956	TIGRFAM MazG family protein
FPG73_RS10340	COG0693	protein deglycase activity
FPG73_RS10345	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FPG73_RS10355	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FPG73_RS10360	COG1937	Protein conserved in bacteria
FPG73_RS10370	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FPG73_RS10370	COG0674	pyruvate-flavodoxin oxidoreductase activity
FPG73_RS10375	COG1013	pyruvate-flavodoxin oxidoreductase activity
FPG73_RS10380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FPG73_RS10400	COG0205	6-phosphofructokinase activity
FPG73_RS10405	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FPG73_RS10415	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FPG73_RS10430	COG0658	competence protein
FPG73_RS10430	COG2333	competence protein COMEC
FPG73_RS10435	COG1475	DNA binding
FPG73_RS10440	COG1192	Involved in chromosome partitioning
FPG73_RS10445	COG0357	Ribosomal RNA small subunit methyltransferase G
FPG73_RS10450	COG0445	tRNA wobble uridine modification
FPG73_RS10475	COG0863	Belongs to the N(4) N(6)-methyltransferase family
FPG73_RS10500	COG1857	crispr-associated protein
FPG73_RS10520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FPG73_RS10525	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FPG73_RS10555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FPG73_RS10570	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FPG73_RS10575	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FPG73_RS10645	COG2205	protein histidine kinase activity
FPG73_RS10650	COG0745	RESPONSE REGULATOR receiver
FPG73_RS10655	COG2010	Cytochrome c
FPG73_RS10695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FPG73_RS10700	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FPG73_RS10705	COG0363	glucosamine-6-phosphate deaminase activity
FPG73_RS10720	COG0730	response to heat
FPG73_RS10750	COG0671	phosphoesterase, PA-phosphatase related
FPG73_RS10760	COG0642	Histidine kinase
FPG73_RS10765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FPG73_RS10775	COG1914	H( )-stimulated, divalent metal cation uptake system
FPG73_RS10795	COG2329	Antibiotic biosynthesis monooxygenase
FPG73_RS10880	COG0745	RESPONSE REGULATOR receiver
FPG73_RS10885	COG5002	protein histidine kinase activity
FPG73_RS10885	COG3850	Histidine kinase
FPG73_RS10945	COG1942	4-Oxalocrotonate Tautomerase
FPG73_RS10955	COG2084	Dehydrogenase
FPG73_RS11005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPG73_RS11040	COG1252	NADH dehydrogenase
FPG73_RS11045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FPG73_RS11055	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FPG73_RS11115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FPG73_RS11135	COG2010	Cytochrome c
FPG73_RS11140	COG0535	radical SAM domain protein
FPG73_RS11155	COG3256	nitric oxide reductase
FPG73_RS11205	COG1192	Involved in chromosome partitioning
FPG73_RS11210	COG1475	DNA binding
FPG73_RS11220	COG1475	DNA binding
FPG73_RS11240	COG3345	alpha-galactosidase
FPG73_RS11245	COG1085	galactose-1-phosphate uridylyltransferase
FPG73_RS11275	COG1304	FMN binding
FPG73_RS11285	COG1487	ribonuclease activity
FPG73_RS11310	COG2124	cytochrome p450
FPG73_RS11320	COG1562	ergosterol biosynthetic process
FPG73_RS11330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FPG73_RS11340	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FPG73_RS11355	COG1175	transmembrane transport
FPG73_RS11370	COG1028	Short-chain dehydrogenase reductase Sdr
FPG73_RS11375	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FPG73_RS11390	COG0800	Aldolase
FPG73_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
FPG73_RS11430	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FPG73_RS11435	COG1785	Belongs to the alkaline phosphatase family
FPG73_RS11440	COG1492	cobalamin metabolic process
FPG73_RS11475	COG0778	Nitroreductase
FPG73_RS11480	COG1648	precorrin-2 dehydrogenase activity
FPG73_RS11480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FPG73_RS11525	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FPG73_RS11530	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FPG73_RS11535	COG0588	phosphoglycerate mutase activity
FPG73_RS11550	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FPG73_RS11560	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FPG73_RS11565	COG1797	cobyrinic acid a,c-diamide synthase activity
FPG73_RS11575	COG3335	DDE superfamily endonuclease
FPG73_RS11580	COG2211	Major facilitator Superfamily
FPG73_RS11605	COG2211	Major facilitator Superfamily
FPG73_RS11615	COG0739	heme binding