locus-tag	class	description
JQN53_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JQN53_RS00010	COG0592	DNA-directed DNA polymerase activity
JQN53_RS00015	COG0148	phosphopyruvate hydratase activity
JQN53_RS00020	COG0469	pyruvate kinase activity
JQN53_RS00030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JQN53_RS00035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JQN53_RS00045	COG1842	Phage shock protein A
JQN53_RS00065	COG0406	alpha-ribazole phosphatase activity
JQN53_RS00070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JQN53_RS00075	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JQN53_RS00085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JQN53_RS00090	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JQN53_RS00095	COG1496	oxidoreductase activity
JQN53_RS00100	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JQN53_RS00105	COG1278	Cold shock
JQN53_RS00110	COG1653	transport
JQN53_RS00125	COG0033	Phosphoglucomutase
JQN53_RS00155	COG0517	IMP dehydrogenase activity
JQN53_RS00155	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JQN53_RS00160	COG1950	PFAM Membrane protein of
JQN53_RS00165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JQN53_RS00175	COG0181	hydroxymethylbilane synthase activity
JQN53_RS00185	COG0285	dihydrofolate synthase activity
JQN53_RS00190	COG0436	Aminotransferase
JQN53_RS00195	COG0521	Mo-molybdopterin cofactor biosynthetic process
JQN53_RS00220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JQN53_RS00225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JQN53_RS00230	COG1993	acr, cog1993
JQN53_RS00235	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JQN53_RS00245	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JQN53_RS00255	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JQN53_RS00260	COG1335	isochorismatase
JQN53_RS00265	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JQN53_RS00280	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JQN53_RS00285	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JQN53_RS00300	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JQN53_RS00305	COG1660	Displays ATPase and GTPase activities
JQN53_RS00310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JQN53_RS00355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JQN53_RS00355	COG1845	cytochrome c oxidase, subunit III
JQN53_RS00360	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JQN53_RS00360	COG2010	Cytochrome c
JQN53_RS00365	COG1612	heme a metabolic process
JQN53_RS00365	COG0109	protoheme IX farnesyltransferase activity
JQN53_RS00380	COG0343	queuine tRNA-ribosyltransferase activity
JQN53_RS00385	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JQN53_RS00390	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JQN53_RS00410	COG1940	carbohydrate kinase activity
JQN53_RS00420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JQN53_RS00425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JQN53_RS00435	COG1611	Belongs to the LOG family
JQN53_RS00445	COG1011	Hydrolase
JQN53_RS00450	COG0632	four-way junction helicase activity
JQN53_RS00455	COG1024	Enoyl-CoA hydratase
JQN53_RS00465	COG0508	dehydrogenase complex catalyzes the overall conversion of
JQN53_RS00475	COG0137	argininosuccinate synthase activity
JQN53_RS00480	COG0165	Argininosuccinate lyase
JQN53_RS00500	COG0505	Belongs to the CarA family
JQN53_RS00510	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JQN53_RS00515	COG0166	Belongs to the GPI family
JQN53_RS00525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JQN53_RS00530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JQN53_RS00535	COG0459	protein refolding
JQN53_RS00540	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JQN53_RS00545	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JQN53_RS00555	COG0778	Nitroreductase
JQN53_RS00560	COG0791	NLP P60 protein
JQN53_RS00560	COG1388	LysM domain
JQN53_RS00570	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JQN53_RS00580	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JQN53_RS00585	COG0581	inorganic phosphate transmembrane transporter activity
JQN53_RS00590	COG0573	inorganic phosphate transmembrane transporter activity
JQN53_RS00595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JQN53_RS00600	COG0482	sulfurtransferase activity
JQN53_RS00610	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JQN53_RS00615	COG0735	belongs to the Fur family
JQN53_RS00630	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JQN53_RS00655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JQN53_RS00660	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JQN53_RS00665	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JQN53_RS00670	COG0250	Participates in transcription elongation, termination and antitermination
JQN53_RS00680	COG0081	regulation of translation
JQN53_RS00695	COG0629	single-stranded DNA binding
JQN53_RS00700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JQN53_RS00705	COG0359	binds to the 23S rRNA
JQN53_RS00710	COG0300	oxidoreductase activity
JQN53_RS00720	COG0321	lipoyl(octanoyl) transferase activity
JQN53_RS00725	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JQN53_RS00755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JQN53_RS00770	COG1598	PFAM Uncharacterised protein family UPF0150
JQN53_RS00775	COG0022	dehydrogenase e1 component
JQN53_RS00780	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JQN53_RS00785	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JQN53_RS00810	COG2226	methyltransferase
JQN53_RS00815	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JQN53_RS00825	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JQN53_RS00830	COG1187	pseudouridine synthase activity
JQN53_RS00850	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JQN53_RS00855	COG0686	Belongs to the AlaDH PNT family
JQN53_RS00865	COG1461	Dihydroxyacetone kinase
JQN53_RS00875	COG3584	3D domain protein
JQN53_RS00875	COG3583	domain protein
JQN53_RS00880	COG4591	ABC-type transport system involved in lipoprotein release permease component
JQN53_RS00885	COG0222	ribosome binding
JQN53_RS00890	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JQN53_RS00900	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JQN53_RS00915	COG0697	spore germination
JQN53_RS00930	COG0243	molybdopterin cofactor binding
JQN53_RS00935	COG2272	Belongs to the type-B carboxylesterase lipase family
JQN53_RS00940	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JQN53_RS00950	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JQN53_RS00965	COG0477	Major facilitator Superfamily
JQN53_RS00980	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JQN53_RS00990	COG0105	UTP biosynthetic process
JQN53_RS00995	COG0631	protein serine/threonine phosphatase activity
JQN53_RS01000	COG0583	DNA-binding transcription factor activity
JQN53_RS01010	COG0508	dehydrogenase complex catalyzes the overall conversion of
JQN53_RS01045	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JQN53_RS01055	COG1278	Cold shock
JQN53_RS01060	COG0484	heat shock protein binding
JQN53_RS01065	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JQN53_RS01070	COG1968	undecaprenyl-diphosphatase activity
JQN53_RS01075	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JQN53_RS01080	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JQN53_RS01095	COG1309	transcriptional regulator
JQN53_RS01100	COG4242	Belongs to the peptidase S51 family
JQN53_RS01115	COG0802	atpase or kinase
JQN53_RS01125	COG0539	negative regulation of cytoplasmic translation
JQN53_RS01130	COG0495	leucyl-tRNA aminoacylation
JQN53_RS01150	COG1902	pentaerythritol trinitrate reductase activity
JQN53_RS01175	COG2414	aldehyde ferredoxin oxidoreductase
JQN53_RS01190	COG1187	pseudouridine synthase activity
JQN53_RS01200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JQN53_RS01205	COG0745	RESPONSE REGULATOR receiver
JQN53_RS01210	COG4191	Histidine kinase
JQN53_RS01215	COG0704	Plays a role in the regulation of phosphate uptake
JQN53_RS01230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JQN53_RS01240	COG0515	serine threonine protein kinase
JQN53_RS01240	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JQN53_RS01265	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JQN53_RS01270	COG1028	Short-chain dehydrogenase reductase Sdr
JQN53_RS01285	COG0717	Belongs to the dCTP deaminase family
JQN53_RS01290	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JQN53_RS01295	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JQN53_RS01300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JQN53_RS01310	COG0583	DNA-binding transcription factor activity
JQN53_RS01315	COG3546	catalase activity
JQN53_RS01320	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JQN53_RS01320	COG0758	DNA mediated transformation
JQN53_RS01325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JQN53_RS01340	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JQN53_RS01350	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
JQN53_RS01355	COG0442	prolyl-tRNA aminoacylation
JQN53_RS01360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JQN53_RS01380	COG0303	'Molybdopterin
JQN53_RS01385	COG0513	Belongs to the DEAD box helicase family
JQN53_RS01395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JQN53_RS01405	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JQN53_RS01425	COG2070	2-Nitropropane dioxygenase
JQN53_RS01440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JQN53_RS01445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JQN53_RS01450	COG0018	arginyl-trna synthetase
JQN53_RS01455	COG1007	ATP synthesis coupled electron transport
JQN53_RS01460	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JQN53_RS01465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JQN53_RS01470	COG0713	ATP synthesis coupled electron transport
JQN53_RS01475	COG0839	Belongs to the complex I subunit 6 family
JQN53_RS01480	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JQN53_RS01485	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JQN53_RS01490	COG1034	ATP synthesis coupled electron transport
JQN53_RS01495	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JQN53_RS01500	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
JQN53_RS01505	COG0649	NAD binding
JQN53_RS01510	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JQN53_RS01515	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JQN53_RS01520	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JQN53_RS01525	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JQN53_RS01535	COG4712	double-strand break repair protein
JQN53_RS01550	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JQN53_RS01565	COG0135	phosphoribosylanthranilate isomerase activity
JQN53_RS01570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JQN53_RS01570	COG1372	Participates in initiation and elongation during chromosome replication
JQN53_RS01575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JQN53_RS01585	COG2720	vancomycin resistance protein
JQN53_RS01590	COG1126	abc transporter atp-binding protein
JQN53_RS01620	COG0277	FAD linked oxidase domain protein
JQN53_RS01630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JQN53_RS01635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JQN53_RS01650	COG0314	molybdopterin synthase activity
JQN53_RS01655	COG1420	regulation of RNA biosynthetic process
JQN53_RS01660	COG0347	Belongs to the P(II) protein family
JQN53_RS01665	COG0004	ammonium transporteR
JQN53_RS01675	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JQN53_RS01685	COG0123	including yeast histone deacetylase and acetoin utilization protein
JQN53_RS01700	COG1597	lipid kinase activity
JQN53_RS01715	COG0436	Aminotransferase
JQN53_RS01725	COG0475	glutathione-regulated potassium exporter activity
JQN53_RS01725	COG0569	domain protein
JQN53_RS01735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JQN53_RS01745	COG0277	FAD linked oxidase domain protein
JQN53_RS01795	COG2002	toxin-antitoxin pair type II binding
JQN53_RS01835	COG0667	Aldo Keto reductase
JQN53_RS01850	COG2199	diguanylate cyclase activity
JQN53_RS01860	COG1067	ATP-dependent peptidase activity
JQN53_RS01865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JQN53_RS01875	COG0745	RESPONSE REGULATOR receiver
JQN53_RS01880	COG2105	PFAM AIG2 family protein
JQN53_RS01885	COG0297	glycogen (starch) synthase activity
JQN53_RS01895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JQN53_RS01900	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JQN53_RS01915	COG0142	geranyltranstransferase activity
JQN53_RS01925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JQN53_RS01945	COG1028	Short-chain dehydrogenase reductase Sdr
JQN53_RS01950	COG0492	ferredoxin-NADP+ reductase activity
JQN53_RS01960	COG0792	nuclease activity
JQN53_RS01965	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JQN53_RS01980	COG1175	transmembrane transport
JQN53_RS01985	COG0395	ABC-type sugar transport system, permease component
JQN53_RS02015	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JQN53_RS02020	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JQN53_RS02025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JQN53_RS02030	COG0805	protein transport
JQN53_RS02035	COG1605	Chorismate mutase
JQN53_RS02035	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JQN53_RS02050	COG0346	lactoylglutathione lyase activity
JQN53_RS02090	COG1063	alcohol dehydrogenase
JQN53_RS02120	COG2255	four-way junction helicase activity
JQN53_RS02125	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JQN53_RS02130	COG0564	pseudouridine synthase activity
JQN53_RS02140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JQN53_RS02145	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JQN53_RS02150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JQN53_RS02155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JQN53_RS02165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JQN53_RS02170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JQN53_RS02175	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JQN53_RS02210	COG0778	Nitroreductase
JQN53_RS02230	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JQN53_RS02235	COG0131	Imidazoleglycerol-phosphate dehydratase
JQN53_RS02240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JQN53_RS02245	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JQN53_RS02250	COG0516	GMP reductase activity
JQN53_RS02250	COG0517	IMP dehydrogenase activity
JQN53_RS02265	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JQN53_RS02280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JQN53_RS02290	COG2890	protein-(glutamine-N5) methyltransferase activity
JQN53_RS02300	COG0706	membrane insertase activity
JQN53_RS02305	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JQN53_RS02310	COG0594	ribonuclease P activity
JQN53_RS02315	COG0230	Belongs to the bacterial ribosomal protein bL34 family
JQN53_RS02325	COG1022	Amp-dependent synthetase and ligase
JQN53_RS02350	COG1121	(ABC) transporter
JQN53_RS02355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JQN53_RS02360	COG1959	2 iron, 2 sulfur cluster binding
JQN53_RS02365	COG1104	cysteine desulfurase activity
JQN53_RS02370	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JQN53_RS02375	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JQN53_RS02390	COG1028	Short-chain dehydrogenase reductase Sdr
JQN53_RS02415	COG0492	ferredoxin-NADP+ reductase activity
JQN53_RS02420	COG0604	alcohol dehydrogenase
JQN53_RS02420	COG3321	synthase
JQN53_RS02420	COG1028	Short-chain dehydrogenase reductase Sdr
JQN53_RS02425	COG0747	negative chemotaxis
JQN53_RS02430	COG0601	transmembrane transport
JQN53_RS02435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JQN53_RS02450	COG0517	IMP dehydrogenase activity
JQN53_RS02455	COG0123	including yeast histone deacetylase and acetoin utilization protein
JQN53_RS02460	COG2104	thiamine diphosphate biosynthetic process
JQN53_RS02465	COG0037	tRNA processing
JQN53_RS02480	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JQN53_RS02485	COG0366	Alpha amylase catalytic
JQN53_RS02490	COG2226	methyltransferase
JQN53_RS02495	COG2226	methyltransferase
JQN53_RS02505	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JQN53_RS02515	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JQN53_RS02520	COG3744	PilT protein domain protein
JQN53_RS02530	COG0460	homoserine dehydrogenase
JQN53_RS02540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JQN53_RS02580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JQN53_RS02600	COG0247	lactate metabolic process
JQN53_RS02605	COG0277	FAD linked oxidase domain protein
JQN53_RS02610	COG0277	FAD linked oxidase domain protein
JQN53_RS02615	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JQN53_RS02620	COG1414	Transcriptional regulator
JQN53_RS02625	COG0789	Transcriptional regulator
JQN53_RS02635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JQN53_RS02640	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JQN53_RS02675	COG0861	Integral membrane protein TerC family
JQN53_RS02680	COG2151	metal-sulfur cluster biosynthetic enzyme
JQN53_RS02685	COG0281	malic enzyme
JQN53_RS02700	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JQN53_RS02705	COG0509	glycine decarboxylation via glycine cleavage system
JQN53_RS02710	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JQN53_RS02715	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JQN53_RS02720	COG0196	riboflavin kinase activity
JQN53_RS02750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JQN53_RS02755	COG2813	Specifically methylates the guanine in position
JQN53_RS02760	COG0527	aspartate kinase activity
JQN53_RS02790	COG4956	integral membrane protein (PIN domain superfamily)
JQN53_RS02795	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JQN53_RS02800	COG0542	response to heat
JQN53_RS02805	COG0423	glycine-tRNA ligase activity
JQN53_RS02815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JQN53_RS02835	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JQN53_RS02835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JQN53_RS02845	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JQN53_RS02855	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JQN53_RS02865	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JQN53_RS02870	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JQN53_RS02875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JQN53_RS02880	COG0114	fumarate hydratase activity
JQN53_RS02885	COG0183	Belongs to the thiolase family
JQN53_RS02900	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JQN53_RS02905	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JQN53_RS02920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JQN53_RS02925	COG1254	Belongs to the acylphosphatase family
JQN53_RS02935	COG1063	alcohol dehydrogenase
JQN53_RS02965	COG2133	pyrroloquinoline quinone binding
JQN53_RS02975	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JQN53_RS02980	COG0154	amidase activity
JQN53_RS03005	COG0572	uridine kinase
JQN53_RS03010	COG3842	ATPase activity
JQN53_RS03025	COG4475	Protein of unknown function (DUF436)
JQN53_RS03080	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JQN53_RS03085	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JQN53_RS03090	COG0803	Belongs to the bacterial solute-binding protein 9 family
JQN53_RS03105	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JQN53_RS03110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JQN53_RS03115	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JQN53_RS03120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JQN53_RS03130	COG0318	PFAM AMP-dependent synthetase and ligase
JQN53_RS03145	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JQN53_RS03150	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JQN53_RS03155	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JQN53_RS03165	COG3870	Protein conserved in bacteria
JQN53_RS03170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JQN53_RS03190	COG0544	peptidyl-prolyl cis-trans isomerase activity
JQN53_RS03195	COG0740	serine-type endopeptidase activity
JQN53_RS03200	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JQN53_RS03205	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JQN53_RS03210	COG0646	methionine synthase
JQN53_RS03210	COG1410	methionine synthase
JQN53_RS03220	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JQN53_RS03245	COG1692	metallophosphoesterase
JQN53_RS03250	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JQN53_RS03255	COG1970	mechanosensitive ion channel activity
JQN53_RS03280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JQN53_RS03290	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JQN53_RS03295	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JQN53_RS03375	COG0438	transferase activity, transferring glycosyl groups
JQN53_RS03395	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JQN53_RS03400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JQN53_RS03420	COG0489	protein tyrosine kinase activity
JQN53_RS03430	COG2264	protein methyltransferase activity
JQN53_RS03435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JQN53_RS03465	COG0574	Belongs to the PEP-utilizing enzyme family
JQN53_RS03465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JQN53_RS03475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JQN53_RS03480	COG2046	Belongs to the sulfate adenylyltransferase family
JQN53_RS03485	COG1648	precorrin-2 dehydrogenase activity
JQN53_RS03485	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JQN53_RS03490	COG0730	response to heat
JQN53_RS03495	COG0175	sulfate reduction
JQN53_RS03500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JQN53_RS03500	COG1648	precorrin-2 dehydrogenase activity
JQN53_RS03505	COG1587	Uroporphyrinogen-III synthase
JQN53_RS03510	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JQN53_RS03520	COG0352	thiamine-phosphate diphosphorylase activity
JQN53_RS03525	COG2104	thiamine diphosphate biosynthetic process
JQN53_RS03530	COG2022	thiamine diphosphate biosynthetic process
JQN53_RS03535	COG2022	thiamine diphosphate biosynthetic process
JQN53_RS03535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JQN53_RS03540	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JQN53_RS03545	COG0477	Major facilitator Superfamily
JQN53_RS03550	COG0351	phosphomethylpyrimidine kinase
JQN53_RS03550	COG0352	thiamine-phosphate diphosphorylase activity
JQN53_RS03580	COG1175	transmembrane transport
JQN53_RS03590	COG1940	carbohydrate kinase activity
JQN53_RS03595	COG0183	Belongs to the thiolase family
JQN53_RS03620	COG2030	dehydratase
JQN53_RS03630	COG0596	Alpha beta hydrolase
JQN53_RS03635	COG0318	PFAM AMP-dependent synthetase and ligase
JQN53_RS03650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JQN53_RS03650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JQN53_RS03660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JQN53_RS03670	COG0195	Participates in both transcription termination and antitermination
JQN53_RS03675	COG0779	Required for maturation of 30S ribosomal subunits
JQN53_RS03685	COG0739	heme binding
JQN53_RS03690	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JQN53_RS03695	COG0640	Transcriptional regulator
JQN53_RS03700	COG2217	Heavy metal translocating P-type atpase
JQN53_RS03705	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JQN53_RS03710	COG0017	Asparaginyl-tRNA synthetase
JQN53_RS03715	COG0561	phosphatase activity
JQN53_RS03720	COG0384	phenazine biosynthesis protein PhzF
JQN53_RS03730	COG0124	histidyl-tRNA synthetase
JQN53_RS03740	COG3842	ATPase activity
JQN53_RS03755	COG1573	uracil-dna glycosylase
JQN53_RS03775	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JQN53_RS03780	COG0519	Catalyzes the synthesis of GMP from XMP
JQN53_RS03780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JQN53_RS03790	COG1316	TRANSCRIPTIONal
JQN53_RS03800	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JQN53_RS03855	COG0295	cytidine deaminase activity
JQN53_RS03865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JQN53_RS03875	COG1760	l-serine dehydratase
JQN53_RS03885	COG0481	GTPase activity
JQN53_RS03895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JQN53_RS03910	COG1028	Short-chain dehydrogenase reductase Sdr
JQN53_RS03935	COG0405	Gamma-glutamyltransferase
JQN53_RS03955	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JQN53_RS03960	COG2873	o-acetylhomoserine
JQN53_RS03975	COG1063	alcohol dehydrogenase
JQN53_RS03985	COG3191	aminopeptidase activity
JQN53_RS03990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JQN53_RS03995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JQN53_RS04000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JQN53_RS04010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JQN53_RS04020	COG0167	dihydroorotate dehydrogenase activity
JQN53_RS04030	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JQN53_RS04035	COG0540	Belongs to the ATCase OTCase family
JQN53_RS04040	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JQN53_RS04050	COG0730	response to heat
JQN53_RS04055	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JQN53_RS04065	COG1960	acyl-CoA dehydrogenase activity
JQN53_RS04070	COG0456	acetyltransferase
JQN53_RS04080	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JQN53_RS04085	COG0009	L-threonylcarbamoyladenylate synthase
JQN53_RS04090	COG1459	type II secretion system
JQN53_RS04105	COG0277	FAD linked oxidase domain protein
JQN53_RS04125	COG0287	Prephenate dehydrogenase
JQN53_RS04130	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JQN53_RS04135	COG2514	catechol 2,3-dioxygenase activity
JQN53_RS04140	COG2353	YceI-like domain
JQN53_RS04145	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
JQN53_RS04150	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JQN53_RS04170	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JQN53_RS04175	COG0179	Fumarylacetoacetate (FAA) hydrolase
JQN53_RS04185	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JQN53_RS04190	COG0151	Belongs to the GarS family
JQN53_RS04195	COG5002	protein histidine kinase activity
JQN53_RS04195	COG2176	DNA-directed DNA polymerase activity
JQN53_RS04225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JQN53_RS04235	COG0217	transcriptional regulatory protein
JQN53_RS04245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JQN53_RS04250	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JQN53_RS04255	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JQN53_RS04260	COG1674	ftsk spoiiie
JQN53_RS04275	COG0517	IMP dehydrogenase activity
JQN53_RS04290	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JQN53_RS04290	COG0617	tRNA 3'-terminal CCA addition
JQN53_RS04290	COG3620	sequence-specific DNA binding
JQN53_RS04300	COG1994	Peptidase M50
JQN53_RS04305	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JQN53_RS04315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JQN53_RS04330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JQN53_RS04335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JQN53_RS04340	COG2719	SpoVR family
JQN53_RS04345	COG2718	Belongs to the UPF0229 family
JQN53_RS04350	COG2766	serine protein kinase
JQN53_RS04375	COG2137	regulation of response to DNA damage stimulus
JQN53_RS04385	COG2359	stage V sporulation protein S
JQN53_RS04390	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JQN53_RS04395	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JQN53_RS04405	COG0463	Glycosyl transferase, family 2
JQN53_RS04410	COG0750	zinc metalloprotease
JQN53_RS04415	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JQN53_RS04420	COG4589	Belongs to the CDS family
JQN53_RS04425	COG0233	cytoplasmic translational termination
JQN53_RS04430	COG0528	UMP kinase activity
JQN53_RS04435	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JQN53_RS04440	COG0052	Belongs to the universal ribosomal protein uS2 family
JQN53_RS04555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JQN53_RS04560	COG0494	nUDIX hydrolase
JQN53_RS04590	COG0402	S-adenosylhomocysteine deaminase activity
JQN53_RS04600	COG4948	Mandelate Racemase Muconate Lactonizing
JQN53_RS04605	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JQN53_RS04610	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JQN53_RS04615	COG1811	Na channel or pump
JQN53_RS04620	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JQN53_RS04620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JQN53_RS04635	COG1215	transferase activity, transferring glycosyl groups
JQN53_RS04645	COG1215	transferase activity, transferring glycosyl groups
JQN53_RS04655	COG0438	transferase activity, transferring glycosyl groups
JQN53_RS04660	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JQN53_RS04685	COG1024	Enoyl-CoA hydratase
JQN53_RS04685	COG1250	3-hydroxyacyl-CoA dehydrogenase
JQN53_RS04690	COG0183	Belongs to the thiolase family
JQN53_RS04695	COG1960	acyl-CoA dehydrogenase activity
JQN53_RS04700	COG0215	cysteine-tRNA ligase activity
JQN53_RS04705	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JQN53_RS04715	COG2738	Putative neutral zinc metallopeptidase
JQN53_RS04730	COG1196	nuclear chromosome segregation
JQN53_RS04745	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JQN53_RS04750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JQN53_RS04750	COG3153	acetyltransferase
JQN53_RS04755	COG1268	BioY protein
JQN53_RS04765	COG0126	phosphoglycerate kinase activity
JQN53_RS04770	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JQN53_RS04775	COG0824	Thioesterase
JQN53_RS04785	COG0557	exoribonuclease II activity
JQN53_RS04790	COG1355	regulation of microtubule-based process
JQN53_RS04795	COG0617	tRNA 3'-terminal CCA addition
JQN53_RS04795	COG1353	crispr-associated protein
JQN53_RS04800	COG0237	dephospho-CoA kinase activity
JQN53_RS04815	COG0742	ribosomal rna small subunit methyltransferase
JQN53_RS04820	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JQN53_RS04825	COG0138	bifunctional purine biosynthesis protein purh
JQN53_RS04830	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JQN53_RS04845	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JQN53_RS04895	COG0149	triose-phosphate isomerase activity
JQN53_RS04900	COG3239	Fatty acid desaturase
JQN53_RS04905	COG1490	D-aminoacyl-tRNA deacylase activity
JQN53_RS04910	COG1307	EDD domain protein, DegV family
JQN53_RS04915	COG1307	EDD domain protein, DegV family
JQN53_RS04920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JQN53_RS04925	COG1510	regulation of RNA biosynthetic process
JQN53_RS04935	COG3769	mannosylglycerate metabolic process
JQN53_RS04950	COG1012	belongs to the aldehyde dehydrogenase family
JQN53_RS04955	COG2368	4-hydroxyphenylacetate
JQN53_RS04960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JQN53_RS04990	COG2050	protein possibly involved in aromatic compounds catabolism
JQN53_RS04995	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JQN53_RS05005	COG1012	belongs to the aldehyde dehydrogenase family
JQN53_RS05005	COG2030	dehydratase
JQN53_RS05025	COG3396	Phenylacetate-CoA oxygenase
JQN53_RS05035	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JQN53_RS05065	COG5297	Belongs to the glycosyl hydrolase family 6
JQN53_RS05065	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
JQN53_RS05090	COG1192	Involved in chromosome partitioning
JQN53_RS05095	COG1475	DNA binding
JQN53_RS05125	COG4966	pilus assembly protein PilW
JQN53_RS05150	COG3345	alpha-galactosidase
JQN53_RS05155	COG1085	galactose-1-phosphate uridylyltransferase
JQN53_RS05175	COG1304	FMN binding
JQN53_RS05185	COG1487	ribonuclease activity
JQN53_RS05210	COG2124	cytochrome p450
JQN53_RS05220	COG1562	ergosterol biosynthetic process
JQN53_RS05230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JQN53_RS05260	COG0702	epimerase
JQN53_RS05265	COG1233	COG1233 Phytoene dehydrogenase and related
JQN53_RS05285	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JQN53_RS05290	COG2723	6-phospho-beta-galactosidase activity
JQN53_RS05300	COG1175	transmembrane transport
JQN53_RS05315	COG1028	Short-chain dehydrogenase reductase Sdr
JQN53_RS05330	COG1028	Short-chain dehydrogenase reductase Sdr
JQN53_RS05335	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JQN53_RS05360	COG1175	transmembrane transport
JQN53_RS05365	COG0395	ABC-type sugar transport system, permease component
JQN53_RS05395	COG1492	cobalamin metabolic process
JQN53_RS05405	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JQN53_RS05425	COG0778	Nitroreductase
JQN53_RS05430	COG1648	precorrin-2 dehydrogenase activity
JQN53_RS05430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JQN53_RS05475	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
JQN53_RS05480	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JQN53_RS05485	COG0588	phosphoglycerate mutase activity
JQN53_RS05500	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JQN53_RS05515	COG1797	cobyrinic acid a,c-diamide synthase activity
JQN53_RS05550	COG2211	Major facilitator Superfamily
JQN53_RS05570	COG2211	Major facilitator Superfamily
JQN53_RS05615	COG1337	RAMP superfamily
JQN53_RS05670	COG1960	acyl-CoA dehydrogenase activity
JQN53_RS05680	COG1028	Short-chain dehydrogenase reductase Sdr
JQN53_RS05685	COG1012	belongs to the aldehyde dehydrogenase family
JQN53_RS05685	COG2030	dehydratase
JQN53_RS05695	COG0318	PFAM AMP-dependent synthetase and ligase
JQN53_RS05700	COG1028	Short-chain dehydrogenase reductase Sdr
JQN53_RS05720	COG0588	phosphoglycerate mutase activity
JQN53_RS05835	COG2329	Antibiotic biosynthesis monooxygenase
JQN53_RS05845	COG4558	Periplasmic binding protein
JQN53_RS05850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JQN53_RS05855	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JQN53_RS05865	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JQN53_RS05880	COG3706	GGDEF domain
JQN53_RS05945	COG0395	ABC-type sugar transport system, permease component
JQN53_RS05965	COG1980	fructose-bisphosphate aldolase activity
JQN53_RS05970	COG1733	regulation of RNA biosynthetic process
JQN53_RS05980	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JQN53_RS05985	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JQN53_RS05995	COG1331	Highly conserved protein containing a thioredoxin domain
JQN53_RS06000	COG0183	Belongs to the thiolase family
JQN53_RS06005	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JQN53_RS06040	COG1012	belongs to the aldehyde dehydrogenase family
JQN53_RS06050	COG0248	Ppx GppA phosphatase
JQN53_RS06055	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JQN53_RS06085	COG0745	RESPONSE REGULATOR receiver
JQN53_RS06090	COG2205	protein histidine kinase activity
JQN53_RS06110	COG1136	(ABC) transporter
JQN53_RS06115	COG1136	(ABC) transporter
JQN53_RS06115	COG0577	efflux transmembrane transporter activity
JQN53_RS06155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JQN53_RS06180	COG0582	viral genome integration into host DNA
JQN53_RS06190	COG2897	thiosulfate sulfurtransferase activity
JQN53_RS06195	COG1760	l-serine dehydratase
JQN53_RS06200	COG2197	response regulator
JQN53_RS06205	COG0335	large ribosomal subunit rRNA binding
JQN53_RS06210	COG0336	Belongs to the RNA methyltransferase TrmD family
JQN53_RS06215	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JQN53_RS06220	COG1837	Belongs to the UPF0109 family
JQN53_RS06225	COG0228	four-way junction DNA binding
JQN53_RS06240	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JQN53_RS06245	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JQN53_RS06245	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JQN53_RS06250	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JQN53_RS06260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JQN53_RS06270	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JQN53_RS06275	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JQN53_RS06280	COG1702	phosphate starvation-inducible protein PhoH
JQN53_RS06290	COG4864	UPF0365 protein
JQN53_RS06300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JQN53_RS06320	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JQN53_RS06320	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JQN53_RS06330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JQN53_RS06340	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JQN53_RS06345	COG1397	ADP-ribosylglycohydrolase
JQN53_RS06350	COG2239	Acts as a magnesium transporter
JQN53_RS06360	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JQN53_RS06360	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JQN53_RS06370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JQN53_RS06370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JQN53_RS06375	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JQN53_RS06380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JQN53_RS06385	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JQN53_RS06390	COG0006	proline dipeptidase activity
JQN53_RS06400	COG0739	heme binding
JQN53_RS06410	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JQN53_RS06415	COG0254	rRNA binding
JQN53_RS06430	COG2001	Belongs to the MraZ family
JQN53_RS06435	COG0275	rRNA processing
JQN53_RS06445	COG0768	penicillin binding
JQN53_RS06450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JQN53_RS06460	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JQN53_RS06465	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JQN53_RS06470	COG0772	Belongs to the SEDS family
JQN53_RS06475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JQN53_RS06480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JQN53_RS06485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JQN53_RS06505	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JQN53_RS06515	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JQN53_RS06525	COG0159	tryptophan synthase activity
JQN53_RS06530	COG0133	tryptophan synthase activity
JQN53_RS06535	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
JQN53_RS06540	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JQN53_RS06545	COG1744	ABC transporter substrate-binding protein PnrA-like
JQN53_RS06550	COG3845	ABC transporter
JQN53_RS06600	COG0438	transferase activity, transferring glycosyl groups
JQN53_RS06605	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JQN53_RS06615	COG0039	L-malate dehydrogenase activity
JQN53_RS06620	COG2819	hydrolase of the alpha beta superfamily
JQN53_RS06625	COG0861	Integral membrane protein TerC family
JQN53_RS06635	COG0247	lactate metabolic process
JQN53_RS06635	COG2181	nitrate reductase activity
JQN53_RS06645	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JQN53_RS06650	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JQN53_RS06655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JQN53_RS06665	COG0439	Biotin carboxylase
JQN53_RS06670	COG0511	ligase activity, forming carbon-carbon bonds
JQN53_RS06675	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JQN53_RS06695	COG0010	Belongs to the arginase family
JQN53_RS06710	COG1100	Small GTP-binding protein
JQN53_RS06720	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JQN53_RS06725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JQN53_RS06740	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JQN53_RS06745	COG1185	polyribonucleotide nucleotidyltransferase activity
JQN53_RS06750	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JQN53_RS06760	COG0745	RESPONSE REGULATOR receiver
JQN53_RS06765	COG5002	protein histidine kinase activity
JQN53_RS06770	COG1960	acyl-CoA dehydrogenase activity
JQN53_RS06775	COG2086	electron transfer activity
JQN53_RS06780	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JQN53_RS06790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JQN53_RS06795	COG1573	uracil-dna glycosylase
JQN53_RS06800	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JQN53_RS06800	COG1796	DNA polymerase
JQN53_RS06810	COG2309	aminopeptidase activity
JQN53_RS06825	COG2873	o-acetylhomoserine
JQN53_RS06830	COG2358	TRAP transporter, solute receptor (TAXI family
JQN53_RS06840	COG1126	abc transporter atp-binding protein
JQN53_RS06850	COG1752	Esterase of the alpha-beta hydrolase superfamily
JQN53_RS06855	COG0134	indole-3-glycerol-phosphate synthase activity
JQN53_RS06860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JQN53_RS06870	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JQN53_RS06885	COG0765	amino acid transport
JQN53_RS06890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JQN53_RS06900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JQN53_RS06905	COG0569	domain protein
JQN53_RS06910	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JQN53_RS06920	COG2313	pseudouridylate synthase activity
JQN53_RS06930	COG3001	Fructosamine kinase
JQN53_RS06935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JQN53_RS06945	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
JQN53_RS06975	COG0012	GTP binding
JQN53_RS06980	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JQN53_RS06990	COG0424	maF-like protein
JQN53_RS07005	COG0768	penicillin binding
JQN53_RS07015	COG2322	membrane
JQN53_RS07035	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JQN53_RS07040	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JQN53_RS07050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JQN53_RS07065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JQN53_RS07100	COG1131	(ABC) transporter
JQN53_RS07115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JQN53_RS07130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JQN53_RS07135	COG0440	acetolactate synthase activity
JQN53_RS07140	COG0028	Belongs to the TPP enzyme family
JQN53_RS07145	COG0492	ferredoxin-NADP+ reductase activity
JQN53_RS07150	COG4970	Tfp pilus assembly protein FimT
JQN53_RS07175	COG2165	general secretion pathway protein
JQN53_RS07210	COG0180	Tryptophanyl-tRNA synthetase
JQN53_RS07215	COG0544	peptidyl-prolyl cis-trans isomerase activity
JQN53_RS07220	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JQN53_RS07225	COG0066	3-isopropylmalate dehydratase activity
JQN53_RS07230	COG0473	3-isopropylmalate dehydrogenase activity
JQN53_RS07245	COG0300	oxidoreductase activity
JQN53_RS07250	COG0129	dihydroxy-acid dehydratase activity
JQN53_RS07260	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JQN53_RS07265	COG1177	transmembrane transport
JQN53_RS07270	COG1176	ABC-type spermidine putrescine transport system, permease component I
JQN53_RS07275	COG3842	ATPase activity
JQN53_RS07280	COG0772	Belongs to the SEDS family
JQN53_RS07285	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JQN53_RS07290	COG2894	cell division
JQN53_RS07295	COG1733	regulation of RNA biosynthetic process
JQN53_RS07305	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JQN53_RS07305	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JQN53_RS07315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JQN53_RS07320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JQN53_RS07325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JQN53_RS07330	COG0653	protein targeting
JQN53_RS07335	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JQN53_RS07355	COG0393	Putative heavy-metal-binding
JQN53_RS07360	COG1205	dead DEAH box helicase
JQN53_RS07360	COG1111	helicase
JQN53_RS07375	COG0358	DNA primase activity
JQN53_RS07385	COG1250	3-hydroxyacyl-CoA dehydrogenase
JQN53_RS07390	COG0697	spore germination
JQN53_RS07395	COG0612	Peptidase, M16
JQN53_RS07400	COG0612	Peptidase, M16
JQN53_RS07405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JQN53_RS07420	COG1394	ATPase activity, coupled to movement of substances
JQN53_RS07425	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
JQN53_RS07430	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
JQN53_RS07435	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
JQN53_RS07440	COG1527	subunit (C
JQN53_RS07445	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
JQN53_RS07455	COG1269	ATP hydrolysis coupled proton transport
JQN53_RS07480	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JQN53_RS07490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JQN53_RS07505	COG0419	ATPase involved in DNA repair
JQN53_RS07510	COG0420	3'-5' exonuclease activity
JQN53_RS07530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JQN53_RS07535	COG2884	Cell division ATP-binding protein ftsE
JQN53_RS07540	COG0793	Belongs to the peptidase S41A family
JQN53_RS07550	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JQN53_RS07550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JQN53_RS07555	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JQN53_RS07560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JQN53_RS07570	COG1079	Belongs to the binding-protein-dependent transport system permease family
JQN53_RS07575	COG4603	Belongs to the binding-protein-dependent transport system permease family
JQN53_RS07580	COG1129	ABC transporter
JQN53_RS07585	COG0746	molybdenum cofactor guanylyltransferase activity
JQN53_RS07600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JQN53_RS07620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JQN53_RS07625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JQN53_RS07630	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JQN53_RS07640	COG0517	IMP dehydrogenase activity
JQN53_RS07640	COG1994	Peptidase M50
JQN53_RS07645	COG2358	TRAP transporter, solute receptor (TAXI family
JQN53_RS07665	COG0788	formyltetrahydrofolate deformylase activity
JQN53_RS07670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JQN53_RS07675	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JQN53_RS07680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JQN53_RS07700	COG0737	Belongs to the 5'-nucleotidase family
JQN53_RS07705	COG0174	glutamine synthetase
JQN53_RS07715	COG0559	Belongs to the binding-protein-dependent transport system permease family
JQN53_RS07735	COG0747	negative chemotaxis
JQN53_RS07740	COG0601	transmembrane transport
JQN53_RS07745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JQN53_RS07755	COG0285	dihydrofolate synthase activity
JQN53_RS07760	COG1132	(ABC) transporter
JQN53_RS07765	COG1132	(ABC) transporter
JQN53_RS07770	COG0372	Belongs to the citrate synthase family
JQN53_RS07775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JQN53_RS07780	COG1482	cell wall glycoprotein biosynthetic process
JQN53_RS07790	COG1515	deoxyribonuclease V activity
JQN53_RS07800	COG0776	regulation of translation
JQN53_RS07815	COG2197	response regulator
JQN53_RS07820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JQN53_RS07825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JQN53_RS07830	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JQN53_RS07835	COG1324	tolerance protein
JQN53_RS07850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JQN53_RS07870	COG2205	protein histidine kinase activity
JQN53_RS07880	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JQN53_RS07905	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
JQN53_RS07910	COG0247	lactate metabolic process
JQN53_RS07915	COG1139	Iron-sulfur cluster binding protein
JQN53_RS07920	COG1556	Lactate utilization protein
JQN53_RS07930	COG1752	Esterase of the alpha-beta hydrolase superfamily
JQN53_RS07935	COG0515	serine threonine protein kinase
JQN53_RS07935	COG2815	serine threonine protein kinase
JQN53_RS07945	COG0860	N-Acetylmuramoyl-L-alanine amidase
JQN53_RS07955	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JQN53_RS07985	COG0473	3-isopropylmalate dehydrogenase activity
JQN53_RS08010	COG1450	Type ii and iii secretion system protein
JQN53_RS08015	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JQN53_RS08020	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JQN53_RS08025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JQN53_RS08030	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JQN53_RS08030	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JQN53_RS08035	COG0736	holo-[acyl-carrier-protein] synthase activity
JQN53_RS08050	COG1160	GTP binding
JQN53_RS08055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JQN53_RS08060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JQN53_RS08060	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JQN53_RS08065	COG0083	homoserine kinase activity
JQN53_RS08080	COG0268	Binds directly to 16S ribosomal RNA
JQN53_RS08090	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JQN53_RS08095	COG0723	plastoquinol--plastocyanin reductase activity
JQN53_RS08105	COG3088	subunit of a heme lyase
JQN53_RS08105	COG4235	cytochrome complex assembly
JQN53_RS08110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JQN53_RS08115	COG1138	Cytochrome C-type biogenesis protein
JQN53_RS08120	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JQN53_RS08125	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JQN53_RS08130	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JQN53_RS08135	COG4133	protoheme IX ABC transporter activity
JQN53_RS08140	COG0785	Cytochrome C biogenesis protein
JQN53_RS08145	COG3258	Cytochrome c
JQN53_RS08155	COG0446	pyridine nucleotide-disulphide oxidoreductase
JQN53_RS08170	COG3258	Cytochrome c
JQN53_RS08175	COG2010	Cytochrome c
JQN53_RS08180	COG0737	Belongs to the 5'-nucleotidase family
JQN53_RS08185	COG2010	Cytochrome c
JQN53_RS08190	COG3258	Cytochrome c
JQN53_RS08210	COG2010	Cytochrome c
JQN53_RS08215	COG3842	ATPase activity
JQN53_RS08245	COG0318	PFAM AMP-dependent synthetase and ligase
JQN53_RS08245	COG0318	PFAM AMP-dependent synthetase and ligase
JQN53_RS08250	COG3360	Dodecin
JQN53_RS08265	COG1024	Enoyl-CoA hydratase
JQN53_RS08270	COG0813	purine-nucleoside phosphorylase activity
JQN53_RS08275	COG1136	(ABC) transporter
JQN53_RS08280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JQN53_RS08285	COG2045	Belongs to the ComB family
JQN53_RS08295	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JQN53_RS08305	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JQN53_RS08315	COG0107	imidazoleglycerol-phosphate synthase activity
JQN53_RS08320	COG0140	phosphoribosyl-ATP diphosphatase activity
JQN53_RS08320	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JQN53_RS08330	COG1494	fructose-1,6-bisphosphatase
JQN53_RS08335	COG0686	Belongs to the AlaDH PNT family
JQN53_RS08340	COG0427	acetyl-CoA hydrolase
JQN53_RS08345	COG0084	hydrolase, TatD family'
JQN53_RS08350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JQN53_RS08360	COG0017	Asparaginyl-tRNA synthetase
JQN53_RS08370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JQN53_RS08385	COG2009	succinate dehydrogenase
JQN53_RS08390	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JQN53_RS08420	COG0318	PFAM AMP-dependent synthetase and ligase
JQN53_RS08425	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JQN53_RS08430	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JQN53_RS08435	COG0504	CTP synthase activity
JQN53_RS08450	COG0067	glutamate synthase
JQN53_RS08450	COG0069	glutamate synthase activity
JQN53_RS08450	COG0070	glutamate synthase
JQN53_RS08455	COG0840	transmembrane signaling receptor activity
JQN53_RS08460	COG0305	Participates in initiation and elongation during chromosome replication
JQN53_RS08470	COG0475	glutathione-regulated potassium exporter activity
JQN53_RS08475	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JQN53_RS08475	COG0617	tRNA 3'-terminal CCA addition
JQN53_RS08475	COG0517	IMP dehydrogenase activity
JQN53_RS08490	COG0475	glutathione-regulated potassium exporter activity
JQN53_RS08495	COG0490	domain, Protein
JQN53_RS08515	COG3118	belongs to the thioredoxin family
JQN53_RS08545	COG0542	response to heat
JQN53_RS08555	COG0789	Transcriptional regulator
JQN53_RS08560	COG0484	heat shock protein binding
JQN53_RS08565	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JQN53_RS08570	COG0443	Heat shock 70 kDa protein
JQN53_RS08575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JQN53_RS08580	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JQN53_RS08585	COG0616	signal peptide processing
JQN53_RS08600	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
JQN53_RS08605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JQN53_RS08610	COG0714	Associated with various cellular activities
JQN53_RS08615	COG0574	Belongs to the PEP-utilizing enzyme family
JQN53_RS08615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JQN53_RS08620	COG1272	protein, Hemolysin III
JQN53_RS08630	COG3850	Histidine kinase
JQN53_RS08630	COG5002	protein histidine kinase activity
JQN53_RS08645	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JQN53_RS08660	COG1011	Hydrolase
JQN53_RS08680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JQN53_RS08690	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JQN53_RS08700	COG0047	phosphoribosylformylglycinamidine synthase activity
JQN53_RS08710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JQN53_RS08715	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JQN53_RS08720	COG0116	Belongs to the methyltransferase superfamily
JQN53_RS08735	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JQN53_RS08740	COG0497	DNA recombination
JQN53_RS08750	COG0604	alcohol dehydrogenase
JQN53_RS08770	COG0585	pseudouridine synthase activity
JQN53_RS08785	COG0557	exoribonuclease II activity
JQN53_RS08790	COG0538	isocitrate dehydrogenase activity
JQN53_RS08860	COG0037	tRNA processing
JQN53_RS08860	COG0590	tRNA wobble adenosine to inosine editing
JQN53_RS08885	COG2050	protein possibly involved in aromatic compounds catabolism
JQN53_RS08895	COG0322	excinuclease ABC activity
JQN53_RS08900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JQN53_RS08905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JQN53_RS08910	COG1854	S-ribosylhomocysteine lyase activity
JQN53_RS08915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JQN53_RS08915	COG0519	Catalyzes the synthesis of GMP from XMP
JQN53_RS08925	COG4274	PFAM GYD family protein
JQN53_RS08930	COG0346	lactoylglutathione lyase activity
JQN53_RS08935	COG0328	RNA-DNA hybrid ribonuclease activity
JQN53_RS08940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JQN53_RS08945	COG2095	MarC family integral membrane protein
JQN53_RS08950	COG1438	arginine binding
JQN53_RS08955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JQN53_RS08960	COG1758	RNA polymerase activity
JQN53_RS08965	COG0194	GDP metabolic process
JQN53_RS08975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JQN53_RS08980	COG2385	sporulation resulting in formation of a cellular spore
JQN53_RS08985	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JQN53_RS08995	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
JQN53_RS09035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JQN53_RS09040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JQN53_RS09045	COG1012	belongs to the aldehyde dehydrogenase family
JQN53_RS09050	COG0506	proline dehydrogenase activity
JQN53_RS09065	COG0156	8-amino-7-oxononanoate synthase activity
JQN53_RS09070	COG0827	DNA restriction-modification system
JQN53_RS09070	COG0732	type I restriction modification DNA specificity domain
JQN53_RS09095	COG0187	DNA topoisomerase II activity
JQN53_RS09100	COG1181	Belongs to the D-alanine--D-alanine ligase family
JQN53_RS09105	COG0193	aminoacyl-tRNA hydrolase activity
JQN53_RS09110	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JQN53_RS09135	COG2815	serine threonine protein kinase
JQN53_RS09135	COG0515	serine threonine protein kinase
JQN53_RS09140	COG0631	protein serine/threonine phosphatase activity
JQN53_RS09150	COG2814	Major facilitator Superfamily
JQN53_RS09155	COG0113	porphobilinogen synthase activity
JQN53_RS09160	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JQN53_RS09165	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JQN53_RS09190	COG4946	Tricorn protease homolog
JQN53_RS09190	COG0823	Involved in the tonB-independent uptake of proteins
JQN53_RS09190	COG1506	peptidase
JQN53_RS09195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JQN53_RS09200	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JQN53_RS09220	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JQN53_RS09225	COG1011	Hydrolase
JQN53_RS09250	COG0537	adenosine 5'-monophosphoramidase activity
JQN53_RS09255	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JQN53_RS09260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JQN53_RS09265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JQN53_RS09270	COG0071	Belongs to the small heat shock protein (HSP20) family
JQN53_RS09275	COG2897	thiosulfate sulfurtransferase activity
JQN53_RS09280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JQN53_RS09290	COG1764	response to oxidative stress
JQN53_RS09315	COG3842	ATPase activity
JQN53_RS09320	COG0101	tRNA pseudouridine synthase activity
JQN53_RS09325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JQN53_RS09340	COG0006	proline dipeptidase activity
JQN53_RS09345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JQN53_RS09360	COG1166	arginine decarboxylase activity
JQN53_RS09370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JQN53_RS09375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JQN53_RS09380	COG1611	Belongs to the LOG family
JQN53_RS09385	COG1193	negative regulation of DNA recombination
JQN53_RS09395	COG0366	Alpha amylase catalytic
JQN53_RS09430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JQN53_RS09435	COG0142	geranyltranstransferase activity
JQN53_RS09450	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JQN53_RS09480	COG0203	ribosomal protein L17
JQN53_RS09485	COG0202	RNA polymerase activity
JQN53_RS09490	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JQN53_RS09495	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JQN53_RS09500	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JQN53_RS09510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JQN53_RS09520	COG0563	adenylate kinase activity
JQN53_RS09525	COG0201	protein transport
JQN53_RS09550	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JQN53_RS09555	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JQN53_RS09560	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JQN53_RS09580	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JQN53_RS09585	COG0255	Belongs to the universal ribosomal protein uL29 family
JQN53_RS09590	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JQN53_RS09595	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JQN53_RS09605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JQN53_RS09610	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JQN53_RS09615	COG0089	rRNA binding
JQN53_RS09620	COG0088	Forms part of the polypeptide exit tunnel
JQN53_RS09630	COG0051	transcription antitermination factor activity, RNA binding
JQN53_RS09635	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JQN53_RS09645	COG0049	tRNA binding
JQN53_RS09660	COG0442	prolyl-tRNA aminoacylation
JQN53_RS09680	COG1115	amino acid carrier protein
JQN53_RS09700	COG1489	DNA binding
JQN53_RS09730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JQN53_RS09750	COG0432	Pfam Uncharacterised protein family UPF0047
JQN53_RS09755	COG3253	May function as heme-dependent peroxidase
JQN53_RS09760	COG0668	transmembrane transport
JQN53_RS09770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JQN53_RS09775	COG2217	Heavy metal translocating P-type atpase
JQN53_RS09795	COG0745	RESPONSE REGULATOR receiver
JQN53_RS09800	COG2205	protein histidine kinase activity
JQN53_RS09820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JQN53_RS09825	COG2226	methyltransferase
JQN53_RS09855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JQN53_RS09860	COG0822	iron-sulfur transferase activity
JQN53_RS09880	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JQN53_RS09890	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JQN53_RS09895	COG0284	orotidine-5'-phosphate decarboxylase activity
JQN53_RS09910	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JQN53_RS09920	COG0416	fatty acid biosynthetic process
JQN53_RS09925	COG3118	belongs to the thioredoxin family
JQN53_RS09930	COG1185	polyribonucleotide nucleotidyltransferase activity
JQN53_RS09935	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JQN53_RS09945	COG0438	transferase activity, transferring glycosyl groups
JQN53_RS09970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JQN53_RS09985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JQN53_RS09990	COG3706	GGDEF domain
JQN53_RS10020	COG0437	4 iron, 4 sulfur cluster binding
JQN53_RS10040	COG0825	malonyl-CoA metabolic process
JQN53_RS10045	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JQN53_RS10080	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JQN53_RS10105	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JQN53_RS10110	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JQN53_RS10115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JQN53_RS10120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JQN53_RS10160	COG0315	cyclic pyranopterin monophosphate synthase activity
JQN53_RS10170	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JQN53_RS10185	COG1694	Mazg nucleotide pyrophosphohydrolase
JQN53_RS10190	COG1803	Methylglyoxal synthase
JQN53_RS10200	COG0301	tRNA thio-modification
JQN53_RS10205	COG0154	amidase activity
JQN53_RS10210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JQN53_RS10230	COG2154	pterin-4-alpha-carbinolamine dehydratase
JQN53_RS10235	COG1607	acyl-coa hydrolase
JQN53_RS10245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JQN53_RS10250	COG4149	molybdate abc transporter
JQN53_RS10255	COG1840	ABC-type Fe3 transport system, periplasmic component
JQN53_RS10270	COG0235	Class ii aldolase
JQN53_RS10275	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JQN53_RS10280	COG0085	RNA polymerase activity
JQN53_RS10290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JQN53_RS10295	COG1077	Cell shape determining protein MreB Mrl
JQN53_RS10300	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JQN53_RS10300	COG1418	mRNA catabolic process
JQN53_RS10305	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JQN53_RS10310	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JQN53_RS10315	COG1546	Belongs to the CinA family
JQN53_RS10315	COG1058	Belongs to the CinA family
JQN53_RS10320	COG0354	folic acid binding
JQN53_RS10335	COG4948	Mandelate Racemase Muconate Lactonizing
JQN53_RS10350	COG1175	transmembrane transport
JQN53_RS10360	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JQN53_RS10370	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JQN53_RS10380	COG0577	efflux transmembrane transporter activity
JQN53_RS10380	COG1136	(ABC) transporter
JQN53_RS10385	COG4181	ATPase activity
JQN53_RS10390	COG0446	pyridine nucleotide-disulphide oxidoreductase
JQN53_RS10405	COG0396	ATPase activity
JQN53_RS10410	COG0719	Fe-S assembly protein
JQN53_RS10415	COG0719	Fe-S assembly protein
JQN53_RS10420	COG2146	nitrite reductase [NAD(P)H] activity
JQN53_RS10430	COG0512	Glutamine amidotransferase of anthranilate synthase
JQN53_RS10435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JQN53_RS10480	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JQN53_RS10485	COG2226	methyltransferase
JQN53_RS10490	COG4603	Belongs to the binding-protein-dependent transport system permease family
JQN53_RS10495	COG1079	Belongs to the binding-protein-dependent transport system permease family
JQN53_RS10510	COG1774	PSP1 C-terminal conserved region
JQN53_RS10515	COG0470	DNA polymerase III
JQN53_RS10550	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JQN53_RS10555	COG0302	gtp cyclohydrolase
JQN53_RS10585	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JQN53_RS10595	COG0395	ABC-type sugar transport system, permease component
JQN53_RS10610	COG1131	(ABC) transporter
JQN53_RS10630	COG0556	nucleotide-excision repair
JQN53_RS10635	COG0497	DNA recombination
JQN53_RS10640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JQN53_RS10650	COG0445	tRNA wobble uridine modification
JQN53_RS10670	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JQN53_RS10675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JQN53_RS10675	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JQN53_RS10680	COG1543	Belongs to the glycosyl hydrolase 57 family
JQN53_RS10685	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JQN53_RS10690	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JQN53_RS10705	COG0189	ligase activity
JQN53_RS10720	COG0066	3-isopropylmalate dehydratase activity
JQN53_RS10725	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JQN53_RS10730	COG1598	PFAM Uncharacterised protein family UPF0150
JQN53_RS10740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JQN53_RS10745	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JQN53_RS10750	COG1960	acyl-CoA dehydrogenase activity
JQN53_RS10755	COG0163	prenyltransferase activity
JQN53_RS10795	COG1668	transmembrane transport
JQN53_RS10800	COG4555	ABC transporter
JQN53_RS10810	COG2096	Adenosyltransferase
JQN53_RS10830	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JQN53_RS10835	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JQN53_RS10850	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JQN53_RS10855	COG0723	plastoquinol--plastocyanin reductase activity
JQN53_RS10865	COG2010	Cytochrome c
JQN53_RS10885	COG1653	transport
JQN53_RS10890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JQN53_RS10895	COG1960	acyl-CoA dehydrogenase activity
JQN53_RS10905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JQN53_RS10925	COG0393	Putative heavy-metal-binding
JQN53_RS10935	COG3956	TIGRFAM MazG family protein
JQN53_RS10945	COG0693	protein deglycase activity
JQN53_RS10950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JQN53_RS10960	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JQN53_RS10965	COG1937	Protein conserved in bacteria
JQN53_RS10975	COG0674	pyruvate-flavodoxin oxidoreductase activity
JQN53_RS10975	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JQN53_RS10980	COG1013	pyruvate-flavodoxin oxidoreductase activity
JQN53_RS10985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JQN53_RS11005	COG0205	6-phosphofructokinase activity
JQN53_RS11010	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JQN53_RS11020	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JQN53_RS11035	COG2333	competence protein COMEC
JQN53_RS11035	COG0658	competence protein
JQN53_RS11040	COG1475	DNA binding
JQN53_RS11045	COG1192	Involved in chromosome partitioning
JQN53_RS11050	COG0357	Ribosomal RNA small subunit methyltransferase G
JQN53_RS11055	COG0445	tRNA wobble uridine modification
JQN53_RS11085	COG1175	transmembrane transport
JQN53_RS11105	COG3454	Phosphonate metabolism
JQN53_RS11110	COG4778	phosphonate C-P lyase system protein PhnL
JQN53_RS11120	COG3627	carbon phosphorus lyase activity
JQN53_RS11140	COG3639	organic phosphonate transmembrane transporter activity
JQN53_RS11150	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
JQN53_RS11205	COG1475	DNA binding
JQN53_RS11210	COG1192	Involved in chromosome partitioning
JQN53_RS11240	COG4213	ABC transporter substrate-binding protein
JQN53_RS11245	COG4214	carbohydrate transport
JQN53_RS11250	COG1129	ABC transporter
JQN53_RS11255	COG1940	carbohydrate kinase activity
JQN53_RS11265	COG1070	Carbohydrate kinase
JQN53_RS11275	COG0673	inositol 2-dehydrogenase activity
JQN53_RS11280	COG0300	oxidoreductase activity
JQN53_RS11300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JQN53_RS11340	COG2002	toxin-antitoxin pair type II binding
JQN53_RS11505	COG1074	ATP-dependent DNA helicase activity
JQN53_RS11520	COG1203	CRISPR-associated helicase, Cas3
JQN53_RS11590	COG0395	ABC-type sugar transport system, permease component
JQN53_RS11595	COG1175	transmembrane transport
JQN53_RS11605	COG1692	metallophosphoesterase
JQN53_RS11630	COG1192	Involved in chromosome partitioning