locus-tag	class	description
LDO79_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LDO79_RS00015	COG0592	DNA-directed DNA polymerase activity
LDO79_RS00020	COG0148	phosphopyruvate hydratase activity
LDO79_RS00025	COG0469	pyruvate kinase activity
LDO79_RS00035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDO79_RS00040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LDO79_RS00050	COG1842	Phage shock protein A
LDO79_RS00075	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LDO79_RS00085	COG0142	geranyltranstransferase activity
LDO79_RS00100	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LDO79_RS00105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LDO79_RS00115	COG0297	glycogen (starch) synthase activity
LDO79_RS00120	COG2105	PFAM AIG2 family protein
LDO79_RS00125	COG0745	RESPONSE REGULATOR receiver
LDO79_RS00135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LDO79_RS00140	COG1067	ATP-dependent peptidase activity
LDO79_RS00160	COG0667	Aldo Keto reductase
LDO79_RS00185	COG2002	toxin-antitoxin pair type II binding
LDO79_RS00225	COG0277	FAD linked oxidase domain protein
LDO79_RS00235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LDO79_RS00245	COG0475	glutathione-regulated potassium exporter activity
LDO79_RS00245	COG0569	domain protein
LDO79_RS00260	COG0436	Aminotransferase
LDO79_RS00275	COG1597	lipid kinase activity
LDO79_RS00290	COG0123	including yeast histone deacetylase and acetoin utilization protein
LDO79_RS00300	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LDO79_RS00310	COG0004	ammonium transporteR
LDO79_RS00315	COG0347	Belongs to the P(II) protein family
LDO79_RS00320	COG1420	regulation of RNA biosynthetic process
LDO79_RS00325	COG0314	molybdopterin synthase activity
LDO79_RS00340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDO79_RS00345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LDO79_RS00355	COG0277	FAD linked oxidase domain protein
LDO79_RS00385	COG1126	abc transporter atp-binding protein
LDO79_RS00390	COG2720	vancomycin resistance protein
LDO79_RS00400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDO79_RS00405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDO79_RS00405	COG1372	Participates in initiation and elongation during chromosome replication
LDO79_RS00410	COG0135	phosphoribosylanthranilate isomerase activity
LDO79_RS00425	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LDO79_RS00440	COG4712	double-strand break repair protein
LDO79_RS00450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LDO79_RS00455	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LDO79_RS00460	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LDO79_RS00465	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LDO79_RS00470	COG0649	NAD binding
LDO79_RS00475	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LDO79_RS00480	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LDO79_RS00485	COG1034	ATP synthesis coupled electron transport
LDO79_RS00490	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LDO79_RS00495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LDO79_RS00500	COG0839	Belongs to the complex I subunit 6 family
LDO79_RS00505	COG0713	ATP synthesis coupled electron transport
LDO79_RS00510	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LDO79_RS00515	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LDO79_RS00520	COG1007	ATP synthesis coupled electron transport
LDO79_RS00525	COG0018	arginyl-trna synthetase
LDO79_RS00530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDO79_RS00535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LDO79_RS00550	COG2070	2-Nitropropane dioxygenase
LDO79_RS00570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LDO79_RS00590	COG0513	Belongs to the DEAD box helicase family
LDO79_RS00595	COG0303	'Molybdopterin
LDO79_RS00615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LDO79_RS00620	COG0442	prolyl-tRNA aminoacylation
LDO79_RS00625	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
LDO79_RS00635	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LDO79_RS00650	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LDO79_RS00655	COG0758	DNA mediated transformation
LDO79_RS00655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LDO79_RS00660	COG3546	catalase activity
LDO79_RS00665	COG0583	DNA-binding transcription factor activity
LDO79_RS00685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDO79_RS00690	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LDO79_RS00695	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LDO79_RS00700	COG0717	Belongs to the dCTP deaminase family
LDO79_RS00715	COG1028	Short-chain dehydrogenase reductase Sdr
LDO79_RS00720	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LDO79_RS00745	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDO79_RS00745	COG0515	serine threonine protein kinase
LDO79_RS00755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LDO79_RS00770	COG0704	Plays a role in the regulation of phosphate uptake
LDO79_RS00775	COG4191	Histidine kinase
LDO79_RS00780	COG0745	RESPONSE REGULATOR receiver
LDO79_RS00785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LDO79_RS00795	COG1187	pseudouridine synthase activity
LDO79_RS00815	COG2414	aldehyde ferredoxin oxidoreductase
LDO79_RS00840	COG1902	pentaerythritol trinitrate reductase activity
LDO79_RS00860	COG0495	leucyl-tRNA aminoacylation
LDO79_RS00865	COG0539	negative regulation of cytoplasmic translation
LDO79_RS00875	COG0802	atpase or kinase
LDO79_RS00890	COG4242	Belongs to the peptidase S51 family
LDO79_RS00895	COG1309	transcriptional regulator
LDO79_RS00910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LDO79_RS00915	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LDO79_RS00920	COG1968	undecaprenyl-diphosphatase activity
LDO79_RS00925	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LDO79_RS00930	COG0484	heat shock protein binding
LDO79_RS00935	COG1278	Cold shock
LDO79_RS00945	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LDO79_RS00980	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO79_RS00990	COG0583	DNA-binding transcription factor activity
LDO79_RS00995	COG0631	protein serine/threonine phosphatase activity
LDO79_RS01000	COG0105	UTP biosynthetic process
LDO79_RS01010	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LDO79_RS01025	COG0477	Major facilitator Superfamily
LDO79_RS01040	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO79_RS01050	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LDO79_RS01055	COG2272	Belongs to the type-B carboxylesterase lipase family
LDO79_RS01060	COG0243	molybdopterin cofactor binding
LDO79_RS01070	COG3177	Filamentation induced by cAMP protein fic
LDO79_RS01080	COG0697	spore germination
LDO79_RS01095	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LDO79_RS01105	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LDO79_RS01110	COG0222	ribosome binding
LDO79_RS01115	COG4591	ABC-type transport system involved in lipoprotein release permease component
LDO79_RS01120	COG3584	3D domain protein
LDO79_RS01120	COG3583	domain protein
LDO79_RS01130	COG1461	Dihydroxyacetone kinase
LDO79_RS01140	COG0686	Belongs to the AlaDH PNT family
LDO79_RS01145	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LDO79_RS01155	COG1187	pseudouridine synthase activity
LDO79_RS01160	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LDO79_RS01170	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LDO79_RS01175	COG2226	methyltransferase
LDO79_RS01200	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LDO79_RS01205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LDO79_RS01210	COG0022	dehydrogenase e1 component
LDO79_RS01215	COG1598	PFAM Uncharacterised protein family UPF0150
LDO79_RS01230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDO79_RS01265	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LDO79_RS01270	COG0321	lipoyl(octanoyl) transferase activity
LDO79_RS01275	COG0300	oxidoreductase activity
LDO79_RS01280	COG0359	binds to the 23S rRNA
LDO79_RS01285	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LDO79_RS01290	COG0629	single-stranded DNA binding
LDO79_RS01305	COG0081	regulation of translation
LDO79_RS01315	COG0250	Participates in transcription elongation, termination and antitermination
LDO79_RS01320	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDO79_RS01325	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LDO79_RS01330	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LDO79_RS01355	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LDO79_RS01370	COG0735	belongs to the Fur family
LDO79_RS01375	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LDO79_RS01385	COG0482	sulfurtransferase activity
LDO79_RS01390	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LDO79_RS01395	COG0573	inorganic phosphate transmembrane transporter activity
LDO79_RS01400	COG0581	inorganic phosphate transmembrane transporter activity
LDO79_RS01405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LDO79_RS01415	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LDO79_RS01425	COG0791	NLP P60 protein
LDO79_RS01425	COG1388	LysM domain
LDO79_RS01430	COG0778	Nitroreductase
LDO79_RS01440	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LDO79_RS01445	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LDO79_RS01450	COG0459	protein refolding
LDO79_RS01455	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LDO79_RS01470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDO79_RS01480	COG0166	Belongs to the GPI family
LDO79_RS01485	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LDO79_RS01495	COG0505	Belongs to the CarA family
LDO79_RS01510	COG0165	Argininosuccinate lyase
LDO79_RS01515	COG0137	argininosuccinate synthase activity
LDO79_RS01525	COG1404	Belongs to the peptidase S8 family
LDO79_RS01535	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDO79_RS01545	COG1024	Enoyl-CoA hydratase
LDO79_RS01550	COG0632	four-way junction helicase activity
LDO79_RS01555	COG1011	Hydrolase
LDO79_RS01565	COG1611	Belongs to the LOG family
LDO79_RS01575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDO79_RS01580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDO79_RS01590	COG1940	carbohydrate kinase activity
LDO79_RS01610	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LDO79_RS01615	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LDO79_RS01620	COG0343	queuine tRNA-ribosyltransferase activity
LDO79_RS01635	COG1612	heme a metabolic process
LDO79_RS01635	COG0109	protoheme IX farnesyltransferase activity
LDO79_RS01640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LDO79_RS01640	COG2010	Cytochrome c
LDO79_RS01645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LDO79_RS01645	COG1845	cytochrome c oxidase, subunit III
LDO79_RS01690	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LDO79_RS01695	COG1660	Displays ATPase and GTPase activities
LDO79_RS01700	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LDO79_RS01715	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LDO79_RS01720	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LDO79_RS01735	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LDO79_RS01740	COG1335	isochorismatase
LDO79_RS01745	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LDO79_RS01755	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LDO79_RS01765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LDO79_RS01770	COG1993	acr, cog1993
LDO79_RS01775	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDO79_RS01780	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LDO79_RS01805	COG0521	Mo-molybdopterin cofactor biosynthetic process
LDO79_RS01810	COG0436	Aminotransferase
LDO79_RS01815	COG0285	dihydrofolate synthase activity
LDO79_RS01825	COG0181	hydroxymethylbilane synthase activity
LDO79_RS01835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LDO79_RS01840	COG1950	PFAM Membrane protein of
LDO79_RS01845	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LDO79_RS01845	COG0517	IMP dehydrogenase activity
LDO79_RS01870	COG0033	Phosphoglucomutase
LDO79_RS01885	COG1653	transport
LDO79_RS01900	COG1278	Cold shock
LDO79_RS01905	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LDO79_RS01910	COG1496	oxidoreductase activity
LDO79_RS01915	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LDO79_RS01920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDO79_RS01930	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LDO79_RS01935	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LDO79_RS01940	COG0406	alpha-ribazole phosphatase activity
LDO79_RS01960	COG1028	Short-chain dehydrogenase reductase Sdr
LDO79_RS01965	COG0492	ferredoxin-NADP+ reductase activity
LDO79_RS01975	COG0792	nuclease activity
LDO79_RS01980	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LDO79_RS02000	COG0395	ABC-type sugar transport system, permease component
LDO79_RS02030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LDO79_RS02035	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LDO79_RS02040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDO79_RS02045	COG0805	protein transport
LDO79_RS02050	COG1605	Chorismate mutase
LDO79_RS02050	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LDO79_RS02105	COG1063	alcohol dehydrogenase
LDO79_RS02135	COG2255	four-way junction helicase activity
LDO79_RS02140	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LDO79_RS02145	COG0564	pseudouridine synthase activity
LDO79_RS02160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDO79_RS02165	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LDO79_RS02170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LDO79_RS02175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LDO79_RS02185	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LDO79_RS02190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDO79_RS02195	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LDO79_RS02230	COG0778	Nitroreductase
LDO79_RS02245	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LDO79_RS02250	COG0131	Imidazoleglycerol-phosphate dehydratase
LDO79_RS02255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LDO79_RS02260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDO79_RS02265	COG0516	GMP reductase activity
LDO79_RS02265	COG0517	IMP dehydrogenase activity
LDO79_RS02280	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LDO79_RS02295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDO79_RS02320	COG0706	membrane insertase activity
LDO79_RS02325	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LDO79_RS02330	COG0594	ribonuclease P activity
LDO79_RS02335	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LDO79_RS02345	COG1022	Amp-dependent synthetase and ligase
LDO79_RS02370	COG1121	(ABC) transporter
LDO79_RS02375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDO79_RS02380	COG1959	2 iron, 2 sulfur cluster binding
LDO79_RS02385	COG1104	cysteine desulfurase activity
LDO79_RS02390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LDO79_RS02395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LDO79_RS02410	COG1028	Short-chain dehydrogenase reductase Sdr
LDO79_RS02435	COG0492	ferredoxin-NADP+ reductase activity
LDO79_RS02440	COG1028	Short-chain dehydrogenase reductase Sdr
LDO79_RS02440	COG3321	synthase
LDO79_RS02440	COG0604	alcohol dehydrogenase
LDO79_RS02455	COG0747	negative chemotaxis
LDO79_RS02460	COG0601	transmembrane transport
LDO79_RS02465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO79_RS02480	COG0517	IMP dehydrogenase activity
LDO79_RS02485	COG0123	including yeast histone deacetylase and acetoin utilization protein
LDO79_RS02490	COG2104	thiamine diphosphate biosynthetic process
LDO79_RS02495	COG0037	tRNA processing
LDO79_RS02510	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LDO79_RS02520	COG0366	Alpha amylase catalytic
LDO79_RS02525	COG2226	methyltransferase
LDO79_RS02530	COG2226	methyltransferase
LDO79_RS02540	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LDO79_RS02550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LDO79_RS02555	COG3744	PilT protein domain protein
LDO79_RS02565	COG0460	homoserine dehydrogenase
LDO79_RS02575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LDO79_RS02615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LDO79_RS02635	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
LDO79_RS02645	COG0247	lactate metabolic process
LDO79_RS02650	COG0277	FAD linked oxidase domain protein
LDO79_RS02655	COG0277	FAD linked oxidase domain protein
LDO79_RS02660	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LDO79_RS02665	COG1414	Transcriptional regulator
LDO79_RS02670	COG0789	Transcriptional regulator
LDO79_RS02680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO79_RS02685	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LDO79_RS02720	COG0861	Integral membrane protein TerC family
LDO79_RS02725	COG2151	metal-sulfur cluster biosynthetic enzyme
LDO79_RS02730	COG0281	malic enzyme
LDO79_RS02745	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LDO79_RS02750	COG0509	glycine decarboxylation via glycine cleavage system
LDO79_RS02755	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDO79_RS02760	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDO79_RS02765	COG0196	riboflavin kinase activity
LDO79_RS02795	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LDO79_RS02800	COG2813	Specifically methylates the guanine in position
LDO79_RS02805	COG0527	aspartate kinase activity
LDO79_RS02835	COG4956	integral membrane protein (PIN domain superfamily)
LDO79_RS02840	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LDO79_RS02845	COG0542	response to heat
LDO79_RS02850	COG0423	glycine-tRNA ligase activity
LDO79_RS02860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LDO79_RS02880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDO79_RS02880	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LDO79_RS02890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LDO79_RS02900	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LDO79_RS02910	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LDO79_RS02915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LDO79_RS02920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LDO79_RS02925	COG0114	fumarate hydratase activity
LDO79_RS02930	COG0183	Belongs to the thiolase family
LDO79_RS02945	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LDO79_RS02950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LDO79_RS02965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LDO79_RS02970	COG1254	Belongs to the acylphosphatase family
LDO79_RS02980	COG1063	alcohol dehydrogenase
LDO79_RS02985	COG2133	pyrroloquinoline quinone binding
LDO79_RS02995	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LDO79_RS03000	COG0154	amidase activity
LDO79_RS03025	COG0572	uridine kinase
LDO79_RS03030	COG3842	ATPase activity
LDO79_RS03045	COG4475	Protein of unknown function (DUF436)
LDO79_RS03100	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO79_RS03105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LDO79_RS03110	COG0803	Belongs to the bacterial solute-binding protein 9 family
LDO79_RS03125	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LDO79_RS03130	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LDO79_RS03135	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LDO79_RS03140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LDO79_RS03150	COG0318	PFAM AMP-dependent synthetase and ligase
LDO79_RS03165	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LDO79_RS03170	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LDO79_RS03175	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LDO79_RS03180	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LDO79_RS03190	COG3870	Protein conserved in bacteria
LDO79_RS03195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LDO79_RS03215	COG0544	peptidyl-prolyl cis-trans isomerase activity
LDO79_RS03220	COG0740	serine-type endopeptidase activity
LDO79_RS03225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LDO79_RS03230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LDO79_RS03235	COG0646	methionine synthase
LDO79_RS03235	COG1410	methionine synthase
LDO79_RS03245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LDO79_RS03270	COG1692	metallophosphoesterase
LDO79_RS03275	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LDO79_RS03280	COG1970	mechanosensitive ion channel activity
LDO79_RS03300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDO79_RS03310	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LDO79_RS03315	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LDO79_RS03370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDO79_RS03405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDO79_RS03425	COG0489	protein tyrosine kinase activity
LDO79_RS03435	COG2264	protein methyltransferase activity
LDO79_RS03440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LDO79_RS03475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LDO79_RS03475	COG0574	Belongs to the PEP-utilizing enzyme family
LDO79_RS03485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDO79_RS03490	COG2046	Belongs to the sulfate adenylyltransferase family
LDO79_RS03500	COG0730	response to heat
LDO79_RS03505	COG0175	sulfate reduction
LDO79_RS03510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDO79_RS03510	COG1648	precorrin-2 dehydrogenase activity
LDO79_RS03515	COG1587	Uroporphyrinogen-III synthase
LDO79_RS03520	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDO79_RS03530	COG0352	thiamine-phosphate diphosphorylase activity
LDO79_RS03535	COG2104	thiamine diphosphate biosynthetic process
LDO79_RS03540	COG2022	thiamine diphosphate biosynthetic process
LDO79_RS03545	COG2022	thiamine diphosphate biosynthetic process
LDO79_RS03545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDO79_RS03550	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LDO79_RS03555	COG0477	Major facilitator Superfamily
LDO79_RS03560	COG0351	phosphomethylpyrimidine kinase
LDO79_RS03590	COG1175	transmembrane transport
LDO79_RS03600	COG1940	carbohydrate kinase activity
LDO79_RS03605	COG0183	Belongs to the thiolase family
LDO79_RS03620	COG1028	Short-chain dehydrogenase reductase Sdr
LDO79_RS03640	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDO79_RS03640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDO79_RS03650	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LDO79_RS03660	COG0195	Participates in both transcription termination and antitermination
LDO79_RS03665	COG0779	Required for maturation of 30S ribosomal subunits
LDO79_RS03675	COG0739	heme binding
LDO79_RS03680	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LDO79_RS03685	COG0640	Transcriptional regulator
LDO79_RS03690	COG2217	Heavy metal translocating P-type atpase
LDO79_RS03695	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LDO79_RS03700	COG0017	Asparaginyl-tRNA synthetase
LDO79_RS03705	COG0561	phosphatase activity
LDO79_RS03710	COG0384	phenazine biosynthesis protein PhzF
LDO79_RS03720	COG0124	histidyl-tRNA synthetase
LDO79_RS03730	COG3842	ATPase activity
LDO79_RS03745	COG1573	uracil-dna glycosylase
LDO79_RS03765	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LDO79_RS03770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LDO79_RS03770	COG0519	Catalyzes the synthesis of GMP from XMP
LDO79_RS03780	COG1316	TRANSCRIPTIONal
LDO79_RS03790	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LDO79_RS03835	COG0295	cytidine deaminase activity
LDO79_RS03845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDO79_RS03855	COG1760	l-serine dehydratase
LDO79_RS03865	COG0481	GTPase activity
LDO79_RS03875	COG0463	Glycosyl transferase, family 2
LDO79_RS03900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO79_RS03915	COG1028	Short-chain dehydrogenase reductase Sdr
LDO79_RS03940	COG0405	Gamma-glutamyltransferase
LDO79_RS03960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LDO79_RS03965	COG2873	o-acetylhomoserine
LDO79_RS03980	COG1063	alcohol dehydrogenase
LDO79_RS03990	COG3191	aminopeptidase activity
LDO79_RS03995	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LDO79_RS04005	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO79_RS04010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDO79_RS04015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LDO79_RS04060	COG0167	dihydroorotate dehydrogenase activity
LDO79_RS04070	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LDO79_RS04075	COG0540	Belongs to the ATCase OTCase family
LDO79_RS04080	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LDO79_RS04090	COG0730	response to heat
LDO79_RS04095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDO79_RS04105	COG1960	acyl-CoA dehydrogenase activity
LDO79_RS04110	COG0456	acetyltransferase
LDO79_RS04120	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LDO79_RS04125	COG0009	L-threonylcarbamoyladenylate synthase
LDO79_RS04130	COG1459	type II secretion system
LDO79_RS04145	COG0277	FAD linked oxidase domain protein
LDO79_RS04155	COG0287	Prephenate dehydrogenase
LDO79_RS04160	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LDO79_RS04165	COG2514	catechol 2,3-dioxygenase activity
LDO79_RS04170	COG2353	YceI-like domain
LDO79_RS04175	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LDO79_RS04180	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LDO79_RS04195	COG1609	Transcriptional regulator
LDO79_RS04200	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LDO79_RS04205	COG0179	Fumarylacetoacetate (FAA) hydrolase
LDO79_RS04215	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LDO79_RS04220	COG0151	Belongs to the GarS family
LDO79_RS04225	COG5002	protein histidine kinase activity
LDO79_RS04225	COG2176	DNA-directed DNA polymerase activity
LDO79_RS04255	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDO79_RS04265	COG0217	transcriptional regulatory protein
LDO79_RS04270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LDO79_RS04270	COG4651	solute:proton antiporter activity
LDO79_RS04275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LDO79_RS04280	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LDO79_RS04285	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LDO79_RS04290	COG1674	ftsk spoiiie
LDO79_RS04305	COG0517	IMP dehydrogenase activity
LDO79_RS04320	COG0617	tRNA 3'-terminal CCA addition
LDO79_RS04320	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LDO79_RS04320	COG3620	sequence-specific DNA binding
LDO79_RS04330	COG1994	Peptidase M50
LDO79_RS04335	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LDO79_RS04345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDO79_RS04360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDO79_RS04370	COG2719	SpoVR family
LDO79_RS04375	COG2718	Belongs to the UPF0229 family
LDO79_RS04380	COG2766	serine protein kinase
LDO79_RS04405	COG2137	regulation of response to DNA damage stimulus
LDO79_RS04415	COG2359	stage V sporulation protein S
LDO79_RS04420	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDO79_RS04425	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LDO79_RS04435	COG0463	Glycosyl transferase, family 2
LDO79_RS04440	COG0750	zinc metalloprotease
LDO79_RS04445	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LDO79_RS04450	COG4589	Belongs to the CDS family
LDO79_RS04455	COG0233	cytoplasmic translational termination
LDO79_RS04460	COG0528	UMP kinase activity
LDO79_RS04465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LDO79_RS04470	COG0052	Belongs to the universal ribosomal protein uS2 family
LDO79_RS04480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LDO79_RS04485	COG0494	nUDIX hydrolase
LDO79_RS04525	COG0402	S-adenosylhomocysteine deaminase activity
LDO79_RS04535	COG4948	Mandelate Racemase Muconate Lactonizing
LDO79_RS04540	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LDO79_RS04545	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LDO79_RS04550	COG1811	Na channel or pump
LDO79_RS04555	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LDO79_RS04555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDO79_RS04570	COG1215	transferase activity, transferring glycosyl groups
LDO79_RS04585	COG1215	transferase activity, transferring glycosyl groups
LDO79_RS04595	COG0438	transferase activity, transferring glycosyl groups
LDO79_RS04600	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LDO79_RS04610	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDO79_RS04610	COG1024	Enoyl-CoA hydratase
LDO79_RS04615	COG0183	Belongs to the thiolase family
LDO79_RS04620	COG1960	acyl-CoA dehydrogenase activity
LDO79_RS04625	COG0215	cysteine-tRNA ligase activity
LDO79_RS04630	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LDO79_RS04640	COG2738	Putative neutral zinc metallopeptidase
LDO79_RS04655	COG1196	nuclear chromosome segregation
LDO79_RS04670	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LDO79_RS04675	COG3153	acetyltransferase
LDO79_RS04675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDO79_RS04680	COG1268	BioY protein
LDO79_RS04690	COG0126	phosphoglycerate kinase activity
LDO79_RS04695	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LDO79_RS04700	COG0824	Thioesterase
LDO79_RS04710	COG0557	exoribonuclease II activity
LDO79_RS04720	COG1355	regulation of microtubule-based process
LDO79_RS04725	COG1353	crispr-associated protein
LDO79_RS04725	COG0617	tRNA 3'-terminal CCA addition
LDO79_RS04730	COG0237	dephospho-CoA kinase activity
LDO79_RS04745	COG0742	ribosomal rna small subunit methyltransferase
LDO79_RS04750	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LDO79_RS04755	COG0138	bifunctional purine biosynthesis protein purh
LDO79_RS04760	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LDO79_RS04775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LDO79_RS04830	COG0149	triose-phosphate isomerase activity
LDO79_RS04835	COG3239	Fatty acid desaturase
LDO79_RS04840	COG1490	D-aminoacyl-tRNA deacylase activity
LDO79_RS04845	COG1307	EDD domain protein, DegV family
LDO79_RS04850	COG1307	EDD domain protein, DegV family
LDO79_RS04855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDO79_RS04860	COG1510	regulation of RNA biosynthetic process
LDO79_RS04870	COG3769	mannosylglycerate metabolic process
LDO79_RS04880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDO79_RS04890	COG1012	belongs to the aldehyde dehydrogenase family
LDO79_RS04895	COG2368	4-hydroxyphenylacetate
LDO79_RS04900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LDO79_RS04920	COG2050	protein possibly involved in aromatic compounds catabolism
LDO79_RS04925	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LDO79_RS04935	COG1012	belongs to the aldehyde dehydrogenase family
LDO79_RS04935	COG2030	dehydratase
LDO79_RS04955	COG3396	Phenylacetate-CoA oxygenase
LDO79_RS04965	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LDO79_RS04980	COG0395	ABC-type sugar transport system, permease component
LDO79_RS05000	COG1980	fructose-bisphosphate aldolase activity
LDO79_RS05005	COG1733	regulation of RNA biosynthetic process
LDO79_RS05010	COG2193	ferroxidase activity
LDO79_RS05015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LDO79_RS05020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LDO79_RS05035	COG1331	Highly conserved protein containing a thioredoxin domain
LDO79_RS05040	COG0183	Belongs to the thiolase family
LDO79_RS05045	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LDO79_RS05085	COG1012	belongs to the aldehyde dehydrogenase family
LDO79_RS05115	COG0745	RESPONSE REGULATOR receiver
LDO79_RS05120	COG2205	protein histidine kinase activity
LDO79_RS05135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDO79_RS05140	COG1136	(ABC) transporter
LDO79_RS05145	COG0577	efflux transmembrane transporter activity
LDO79_RS05145	COG1136	(ABC) transporter
LDO79_RS05215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LDO79_RS05250	COG0582	viral genome integration into host DNA
LDO79_RS05260	COG2897	thiosulfate sulfurtransferase activity
LDO79_RS05265	COG1760	l-serine dehydratase
LDO79_RS05270	COG2197	response regulator
LDO79_RS05275	COG0335	large ribosomal subunit rRNA binding
LDO79_RS05280	COG0336	Belongs to the RNA methyltransferase TrmD family
LDO79_RS05285	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LDO79_RS05290	COG1837	Belongs to the UPF0109 family
LDO79_RS05295	COG0228	four-way junction DNA binding
LDO79_RS05310	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LDO79_RS05315	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LDO79_RS05315	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LDO79_RS05320	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LDO79_RS05330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LDO79_RS05340	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LDO79_RS05345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LDO79_RS05350	COG1702	phosphate starvation-inducible protein PhoH
LDO79_RS05360	COG4864	UPF0365 protein
LDO79_RS05370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDO79_RS05390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDO79_RS05390	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDO79_RS05400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDO79_RS05410	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LDO79_RS05415	COG1397	ADP-ribosylglycohydrolase
LDO79_RS05420	COG2239	Acts as a magnesium transporter
LDO79_RS05430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDO79_RS05430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDO79_RS05440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LDO79_RS05440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LDO79_RS05445	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LDO79_RS05450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LDO79_RS05455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LDO79_RS05460	COG0006	proline dipeptidase activity
LDO79_RS05470	COG0739	heme binding
LDO79_RS05480	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LDO79_RS05485	COG0254	rRNA binding
LDO79_RS05500	COG2001	Belongs to the MraZ family
LDO79_RS05505	COG0275	rRNA processing
LDO79_RS05515	COG0768	penicillin binding
LDO79_RS05520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LDO79_RS05530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDO79_RS05535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LDO79_RS05540	COG0772	Belongs to the SEDS family
LDO79_RS05545	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LDO79_RS05550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LDO79_RS05555	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LDO79_RS05575	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LDO79_RS05585	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LDO79_RS05595	COG0159	tryptophan synthase activity
LDO79_RS05600	COG0133	tryptophan synthase activity
LDO79_RS05605	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
LDO79_RS05610	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LDO79_RS05615	COG1744	ABC transporter substrate-binding protein PnrA-like
LDO79_RS05620	COG3845	ABC transporter
LDO79_RS05670	COG0438	transferase activity, transferring glycosyl groups
LDO79_RS05675	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LDO79_RS05685	COG0039	L-malate dehydrogenase activity
LDO79_RS05690	COG2819	hydrolase of the alpha beta superfamily
LDO79_RS05695	COG0861	Integral membrane protein TerC family
LDO79_RS05705	COG2181	nitrate reductase activity
LDO79_RS05705	COG0247	lactate metabolic process
LDO79_RS05715	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
LDO79_RS05720	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LDO79_RS05725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDO79_RS05735	COG0439	Biotin carboxylase
LDO79_RS05740	COG0511	ligase activity, forming carbon-carbon bonds
LDO79_RS05745	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LDO79_RS05765	COG0010	Belongs to the arginase family
LDO79_RS05780	COG1100	Small GTP-binding protein
LDO79_RS05790	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LDO79_RS05795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LDO79_RS05805	COG2814	Major facilitator Superfamily
LDO79_RS05810	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LDO79_RS05815	COG1185	polyribonucleotide nucleotidyltransferase activity
LDO79_RS05820	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LDO79_RS05830	COG0745	RESPONSE REGULATOR receiver
LDO79_RS05835	COG5002	protein histidine kinase activity
LDO79_RS05840	COG1960	acyl-CoA dehydrogenase activity
LDO79_RS05845	COG2086	electron transfer activity
LDO79_RS05850	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LDO79_RS05860	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LDO79_RS05865	COG1573	uracil-dna glycosylase
LDO79_RS05870	COG1796	DNA polymerase
LDO79_RS05870	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LDO79_RS05880	COG2309	aminopeptidase activity
LDO79_RS05895	COG2873	o-acetylhomoserine
LDO79_RS05900	COG2358	TRAP transporter, solute receptor (TAXI family
LDO79_RS05910	COG1126	abc transporter atp-binding protein
LDO79_RS05920	COG1752	Esterase of the alpha-beta hydrolase superfamily
LDO79_RS05925	COG3311	Transcriptional regulator
LDO79_RS05935	COG0134	indole-3-glycerol-phosphate synthase activity
LDO79_RS05940	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LDO79_RS05950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LDO79_RS05965	COG0765	amino acid transport
LDO79_RS05970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDO79_RS05980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDO79_RS05985	COG0569	domain protein
LDO79_RS05990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LDO79_RS05995	COG1426	Protein conserved in bacteria
LDO79_RS06000	COG2313	pseudouridylate synthase activity
LDO79_RS06010	COG3001	Fructosamine kinase
LDO79_RS06015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDO79_RS06025	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LDO79_RS06050	COG0012	GTP binding
LDO79_RS06055	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LDO79_RS06065	COG0424	maF-like protein
LDO79_RS06080	COG0768	penicillin binding
LDO79_RS06090	COG2322	membrane
LDO79_RS06105	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LDO79_RS06110	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LDO79_RS06120	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LDO79_RS06140	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LDO79_RS06150	COG1131	(ABC) transporter
LDO79_RS06165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDO79_RS06180	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LDO79_RS06185	COG0440	acetolactate synthase activity
LDO79_RS06190	COG0028	Belongs to the TPP enzyme family
LDO79_RS06195	COG0492	ferredoxin-NADP+ reductase activity
LDO79_RS06200	COG4970	Tfp pilus assembly protein FimT
LDO79_RS06225	COG2165	general secretion pathway protein
LDO79_RS06255	COG0180	Tryptophanyl-tRNA synthetase
LDO79_RS06260	COG0544	peptidyl-prolyl cis-trans isomerase activity
LDO79_RS06265	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LDO79_RS06270	COG0066	3-isopropylmalate dehydratase activity
LDO79_RS06275	COG0473	3-isopropylmalate dehydrogenase activity
LDO79_RS06290	COG0300	oxidoreductase activity
LDO79_RS06295	COG0129	dihydroxy-acid dehydratase activity
LDO79_RS06305	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LDO79_RS06310	COG1177	transmembrane transport
LDO79_RS06315	COG1176	ABC-type spermidine putrescine transport system, permease component I
LDO79_RS06320	COG3842	ATPase activity
LDO79_RS06325	COG0772	Belongs to the SEDS family
LDO79_RS06330	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LDO79_RS06335	COG2894	cell division
LDO79_RS06340	COG1733	regulation of RNA biosynthetic process
LDO79_RS06350	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LDO79_RS06350	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LDO79_RS06360	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDO79_RS06365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDO79_RS06370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDO79_RS06375	COG0653	protein targeting
LDO79_RS06380	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LDO79_RS06400	COG0393	Putative heavy-metal-binding
LDO79_RS06405	COG1111	helicase
LDO79_RS06405	COG1205	dead DEAH box helicase
LDO79_RS06420	COG0358	DNA primase activity
LDO79_RS06430	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDO79_RS06435	COG0697	spore germination
LDO79_RS06440	COG0612	Peptidase, M16
LDO79_RS06445	COG0612	Peptidase, M16
LDO79_RS06450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LDO79_RS06475	COG1394	ATPase activity, coupled to movement of substances
LDO79_RS06480	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
LDO79_RS06485	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
LDO79_RS06490	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
LDO79_RS06495	COG1527	subunit (C
LDO79_RS06500	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
LDO79_RS06510	COG1269	ATP hydrolysis coupled proton transport
LDO79_RS06535	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LDO79_RS06545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDO79_RS06560	COG0419	ATPase involved in DNA repair
LDO79_RS06565	COG0420	3'-5' exonuclease activity
LDO79_RS06585	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LDO79_RS06590	COG2884	Cell division ATP-binding protein ftsE
LDO79_RS06595	COG0793	Belongs to the peptidase S41A family
LDO79_RS06605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO79_RS06605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDO79_RS06610	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LDO79_RS06615	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LDO79_RS06625	COG1079	Belongs to the binding-protein-dependent transport system permease family
LDO79_RS06630	COG4603	Belongs to the binding-protein-dependent transport system permease family
LDO79_RS06635	COG1129	ABC transporter
LDO79_RS06640	COG0746	molybdenum cofactor guanylyltransferase activity
LDO79_RS06655	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LDO79_RS06675	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LDO79_RS06680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDO79_RS06685	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LDO79_RS06695	COG1994	Peptidase M50
LDO79_RS06695	COG0517	IMP dehydrogenase activity
LDO79_RS06720	COG0788	formyltetrahydrofolate deformylase activity
LDO79_RS06725	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDO79_RS06730	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LDO79_RS06735	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LDO79_RS06755	COG0737	Belongs to the 5'-nucleotidase family
LDO79_RS06760	COG0174	glutamine synthetase
LDO79_RS06770	COG0559	Belongs to the binding-protein-dependent transport system permease family
LDO79_RS06790	COG0747	negative chemotaxis
LDO79_RS06795	COG0601	transmembrane transport
LDO79_RS06800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO79_RS06810	COG0285	dihydrofolate synthase activity
LDO79_RS06815	COG1132	(ABC) transporter
LDO79_RS06820	COG1132	(ABC) transporter
LDO79_RS06825	COG0372	Belongs to the citrate synthase family
LDO79_RS06830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LDO79_RS06835	COG1482	cell wall glycoprotein biosynthetic process
LDO79_RS06845	COG1515	deoxyribonuclease V activity
LDO79_RS06855	COG0776	regulation of translation
LDO79_RS06870	COG2197	response regulator
LDO79_RS06875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDO79_RS06880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LDO79_RS06885	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LDO79_RS06890	COG1324	tolerance protein
LDO79_RS06905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LDO79_RS06925	COG2205	protein histidine kinase activity
LDO79_RS06935	COG0247	lactate metabolic process
LDO79_RS06940	COG1139	Iron-sulfur cluster binding protein
LDO79_RS06945	COG1556	Lactate utilization protein
LDO79_RS06955	COG1752	Esterase of the alpha-beta hydrolase superfamily
LDO79_RS06960	COG0515	serine threonine protein kinase
LDO79_RS06960	COG2815	serine threonine protein kinase
LDO79_RS06970	COG0860	N-Acetylmuramoyl-L-alanine amidase
LDO79_RS06980	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LDO79_RS07010	COG0473	3-isopropylmalate dehydrogenase activity
LDO79_RS07035	COG1450	Type ii and iii secretion system protein
LDO79_RS07040	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LDO79_RS07045	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LDO79_RS07050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LDO79_RS07055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDO79_RS07055	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LDO79_RS07060	COG0736	holo-[acyl-carrier-protein] synthase activity
LDO79_RS07075	COG1160	GTP binding
LDO79_RS07080	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LDO79_RS07085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LDO79_RS07085	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LDO79_RS07090	COG0083	homoserine kinase activity
LDO79_RS07105	COG0268	Binds directly to 16S ribosomal RNA
LDO79_RS07115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LDO79_RS07120	COG0723	plastoquinol--plastocyanin reductase activity
LDO79_RS07130	COG3088	subunit of a heme lyase
LDO79_RS07130	COG4235	cytochrome complex assembly
LDO79_RS07135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDO79_RS07140	COG1138	Cytochrome C-type biogenesis protein
LDO79_RS07145	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LDO79_RS07150	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDO79_RS07155	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDO79_RS07160	COG4133	protoheme IX ABC transporter activity
LDO79_RS07165	COG0785	Cytochrome C biogenesis protein
LDO79_RS07170	COG3258	Cytochrome c
LDO79_RS07180	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDO79_RS07195	COG3258	Cytochrome c
LDO79_RS07200	COG2010	Cytochrome c
LDO79_RS07205	COG0737	Belongs to the 5'-nucleotidase family
LDO79_RS07210	COG2010	Cytochrome c
LDO79_RS07215	COG3258	Cytochrome c
LDO79_RS07235	COG2010	Cytochrome c
LDO79_RS07240	COG3842	ATPase activity
LDO79_RS07270	COG0318	PFAM AMP-dependent synthetase and ligase
LDO79_RS07275	COG3360	Dodecin
LDO79_RS07290	COG1024	Enoyl-CoA hydratase
LDO79_RS07295	COG0813	purine-nucleoside phosphorylase activity
LDO79_RS07300	COG1136	(ABC) transporter
LDO79_RS07305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LDO79_RS07310	COG2045	Belongs to the ComB family
LDO79_RS07320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LDO79_RS07330	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LDO79_RS07340	COG0107	imidazoleglycerol-phosphate synthase activity
LDO79_RS07345	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LDO79_RS07345	COG0140	phosphoribosyl-ATP diphosphatase activity
LDO79_RS07350	COG1494	fructose-1,6-bisphosphatase
LDO79_RS07355	COG0686	Belongs to the AlaDH PNT family
LDO79_RS07360	COG0427	acetyl-CoA hydrolase
LDO79_RS07365	COG0084	hydrolase, TatD family'
LDO79_RS07370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDO79_RS07380	COG0017	Asparaginyl-tRNA synthetase
LDO79_RS07385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LDO79_RS07400	COG2009	succinate dehydrogenase
LDO79_RS07405	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LDO79_RS07435	COG0318	PFAM AMP-dependent synthetase and ligase
LDO79_RS07440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LDO79_RS07445	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LDO79_RS07450	COG0504	CTP synthase activity
LDO79_RS07465	COG0070	glutamate synthase
LDO79_RS07465	COG0067	glutamate synthase
LDO79_RS07465	COG0069	glutamate synthase activity
LDO79_RS07470	COG0840	transmembrane signaling receptor activity
LDO79_RS07475	COG0305	Participates in initiation and elongation during chromosome replication
LDO79_RS07485	COG0475	glutathione-regulated potassium exporter activity
LDO79_RS07490	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LDO79_RS07490	COG0617	tRNA 3'-terminal CCA addition
LDO79_RS07490	COG0517	IMP dehydrogenase activity
LDO79_RS07505	COG0475	glutathione-regulated potassium exporter activity
LDO79_RS07510	COG0490	domain, Protein
LDO79_RS07530	COG3118	belongs to the thioredoxin family
LDO79_RS07560	COG0542	response to heat
LDO79_RS07565	COG0789	Transcriptional regulator
LDO79_RS07570	COG0484	heat shock protein binding
LDO79_RS07575	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LDO79_RS07580	COG0443	Heat shock 70 kDa protein
LDO79_RS07585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LDO79_RS07590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LDO79_RS07595	COG0616	signal peptide processing
LDO79_RS07610	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
LDO79_RS07615	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LDO79_RS07620	COG0714	Associated with various cellular activities
LDO79_RS07625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LDO79_RS07625	COG0574	Belongs to the PEP-utilizing enzyme family
LDO79_RS07630	COG1272	protein, Hemolysin III
LDO79_RS07640	COG3850	Histidine kinase
LDO79_RS07640	COG5002	protein histidine kinase activity
LDO79_RS07655	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LDO79_RS07670	COG1011	Hydrolase
LDO79_RS07690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LDO79_RS07700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LDO79_RS07710	COG0047	phosphoribosylformylglycinamidine synthase activity
LDO79_RS07720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LDO79_RS07725	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LDO79_RS07730	COG0116	Belongs to the methyltransferase superfamily
LDO79_RS07745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDO79_RS07750	COG0497	DNA recombination
LDO79_RS07760	COG0604	alcohol dehydrogenase
LDO79_RS07780	COG0585	pseudouridine synthase activity
LDO79_RS07795	COG0557	exoribonuclease II activity
LDO79_RS07800	COG0473	3-isopropylmalate dehydrogenase activity
LDO79_RS07825	COG4974	Belongs to the 'phage' integrase family
LDO79_RS07835	COG0037	tRNA processing
LDO79_RS07835	COG0590	tRNA wobble adenosine to inosine editing
LDO79_RS07860	COG2050	protein possibly involved in aromatic compounds catabolism
LDO79_RS07870	COG0322	excinuclease ABC activity
LDO79_RS07875	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LDO79_RS07880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LDO79_RS07885	COG1854	S-ribosylhomocysteine lyase activity
LDO79_RS07890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LDO79_RS07890	COG0519	Catalyzes the synthesis of GMP from XMP
LDO79_RS07895	COG4636	protein conserved in cyanobacteria
LDO79_RS07900	COG4274	PFAM GYD family protein
LDO79_RS07905	COG0346	lactoylglutathione lyase activity
LDO79_RS07910	COG0328	RNA-DNA hybrid ribonuclease activity
LDO79_RS07915	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LDO79_RS07920	COG2095	MarC family integral membrane protein
LDO79_RS07925	COG1438	arginine binding
LDO79_RS07930	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LDO79_RS07935	COG1758	RNA polymerase activity
LDO79_RS07940	COG0194	GDP metabolic process
LDO79_RS07950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LDO79_RS07955	COG2385	sporulation resulting in formation of a cellular spore
LDO79_RS07960	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LDO79_RS07970	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LDO79_RS08010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LDO79_RS08015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LDO79_RS08020	COG1012	belongs to the aldehyde dehydrogenase family
LDO79_RS08025	COG0506	proline dehydrogenase activity
LDO79_RS08040	COG0156	8-amino-7-oxononanoate synthase activity
LDO79_RS08045	COG0732	type I restriction modification DNA specificity domain
LDO79_RS08045	COG0827	DNA restriction-modification system
LDO79_RS08060	COG0187	DNA topoisomerase II activity
LDO79_RS08065	COG1181	Belongs to the D-alanine--D-alanine ligase family
LDO79_RS08070	COG0193	aminoacyl-tRNA hydrolase activity
LDO79_RS08075	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LDO79_RS08100	COG2815	serine threonine protein kinase
LDO79_RS08100	COG0515	serine threonine protein kinase
LDO79_RS08105	COG0631	protein serine/threonine phosphatase activity
LDO79_RS08115	COG2814	Major facilitator Superfamily
LDO79_RS08120	COG0113	porphobilinogen synthase activity
LDO79_RS08125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LDO79_RS08130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LDO79_RS08155	COG1506	peptidase
LDO79_RS08155	COG4946	Tricorn protease homolog
LDO79_RS08155	COG0823	Involved in the tonB-independent uptake of proteins
LDO79_RS08160	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LDO79_RS08165	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LDO79_RS08185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LDO79_RS08190	COG1011	Hydrolase
LDO79_RS08215	COG0537	adenosine 5'-monophosphoramidase activity
LDO79_RS08220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LDO79_RS08225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LDO79_RS08230	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LDO79_RS08235	COG0071	Belongs to the small heat shock protein (HSP20) family
LDO79_RS08240	COG2897	thiosulfate sulfurtransferase activity
LDO79_RS08245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDO79_RS08255	COG1764	response to oxidative stress
LDO79_RS08280	COG3842	ATPase activity
LDO79_RS08285	COG0101	tRNA pseudouridine synthase activity
LDO79_RS08290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDO79_RS08295	COG0601	transmembrane transport
LDO79_RS08300	COG0747	negative chemotaxis
LDO79_RS08310	COG0006	proline dipeptidase activity
LDO79_RS08315	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LDO79_RS08330	COG1166	arginine decarboxylase activity
LDO79_RS08335	COG3706	GGDEF domain
LDO79_RS08340	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LDO79_RS08345	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LDO79_RS08350	COG1611	Belongs to the LOG family
LDO79_RS08355	COG1193	negative regulation of DNA recombination
LDO79_RS08365	COG0366	Alpha amylase catalytic
LDO79_RS08400	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LDO79_RS08405	COG0142	geranyltranstransferase activity
LDO79_RS08415	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LDO79_RS08445	COG0203	ribosomal protein L17
LDO79_RS08450	COG0202	RNA polymerase activity
LDO79_RS08455	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LDO79_RS08460	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LDO79_RS08465	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LDO79_RS08475	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LDO79_RS08485	COG0563	adenylate kinase activity
LDO79_RS08490	COG0201	protein transport
LDO79_RS08515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LDO79_RS08520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LDO79_RS08525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LDO79_RS08540	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LDO79_RS08545	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LDO79_RS08550	COG0255	Belongs to the universal ribosomal protein uL29 family
LDO79_RS08555	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LDO79_RS08560	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LDO79_RS08570	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LDO79_RS08575	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LDO79_RS08580	COG0089	rRNA binding
LDO79_RS08585	COG0088	Forms part of the polypeptide exit tunnel
LDO79_RS08595	COG0051	transcription antitermination factor activity, RNA binding
LDO79_RS08610	COG0049	tRNA binding
LDO79_RS08625	COG0442	prolyl-tRNA aminoacylation
LDO79_RS08645	COG1115	amino acid carrier protein
LDO79_RS08665	COG1489	DNA binding
LDO79_RS08690	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LDO79_RS08710	COG0432	Pfam Uncharacterised protein family UPF0047
LDO79_RS08715	COG3253	May function as heme-dependent peroxidase
LDO79_RS08720	COG0668	transmembrane transport
LDO79_RS08730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDO79_RS08735	COG2217	Heavy metal translocating P-type atpase
LDO79_RS08755	COG0745	RESPONSE REGULATOR receiver
LDO79_RS08760	COG2205	protein histidine kinase activity
LDO79_RS08780	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDO79_RS08785	COG2226	methyltransferase
LDO79_RS08815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LDO79_RS08820	COG0822	iron-sulfur transferase activity
LDO79_RS08840	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LDO79_RS08850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LDO79_RS08855	COG0284	orotidine-5'-phosphate decarboxylase activity
LDO79_RS08870	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LDO79_RS08880	COG0416	fatty acid biosynthetic process
LDO79_RS08885	COG3118	belongs to the thioredoxin family
LDO79_RS08890	COG1185	polyribonucleotide nucleotidyltransferase activity
LDO79_RS08895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LDO79_RS08905	COG0438	transferase activity, transferring glycosyl groups
LDO79_RS08925	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LDO79_RS08935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDO79_RS08970	COG0437	4 iron, 4 sulfur cluster binding
LDO79_RS08985	COG0825	malonyl-CoA metabolic process
LDO79_RS08990	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LDO79_RS09025	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LDO79_RS09050	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LDO79_RS09055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LDO79_RS09060	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LDO79_RS09065	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LDO79_RS09105	COG0315	cyclic pyranopterin monophosphate synthase activity
LDO79_RS09115	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LDO79_RS09130	COG1694	Mazg nucleotide pyrophosphohydrolase
LDO79_RS09135	COG1803	Methylglyoxal synthase
LDO79_RS09145	COG0301	tRNA thio-modification
LDO79_RS09150	COG0154	amidase activity
LDO79_RS09155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LDO79_RS09185	COG2154	pterin-4-alpha-carbinolamine dehydratase
LDO79_RS09190	COG1607	acyl-coa hydrolase
LDO79_RS09200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDO79_RS09205	COG4149	molybdate abc transporter
LDO79_RS09210	COG1840	ABC-type Fe3 transport system, periplasmic component
LDO79_RS09225	COG0235	Class ii aldolase
LDO79_RS09230	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LDO79_RS09235	COG0085	RNA polymerase activity
LDO79_RS09245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LDO79_RS09250	COG1077	Cell shape determining protein MreB Mrl
LDO79_RS09255	COG1418	mRNA catabolic process
LDO79_RS09255	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LDO79_RS09260	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LDO79_RS09265	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LDO79_RS09270	COG1058	Belongs to the CinA family
LDO79_RS09270	COG1546	Belongs to the CinA family
LDO79_RS09275	COG0354	folic acid binding
LDO79_RS09290	COG4948	Mandelate Racemase Muconate Lactonizing
LDO79_RS09305	COG1175	transmembrane transport
LDO79_RS09315	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LDO79_RS09325	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LDO79_RS09335	COG0577	efflux transmembrane transporter activity
LDO79_RS09335	COG1136	(ABC) transporter
LDO79_RS09340	COG4181	ATPase activity
LDO79_RS09345	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDO79_RS09360	COG0396	ATPase activity
LDO79_RS09365	COG0719	Fe-S assembly protein
LDO79_RS09370	COG0719	Fe-S assembly protein
LDO79_RS09375	COG2146	nitrite reductase [NAD(P)H] activity
LDO79_RS09385	COG0512	Glutamine amidotransferase of anthranilate synthase
LDO79_RS09390	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LDO79_RS09435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDO79_RS09440	COG2226	methyltransferase
LDO79_RS09445	COG4603	Belongs to the binding-protein-dependent transport system permease family
LDO79_RS09450	COG1079	Belongs to the binding-protein-dependent transport system permease family
LDO79_RS09465	COG1774	PSP1 C-terminal conserved region
LDO79_RS09470	COG0470	DNA polymerase III
LDO79_RS09490	COG0497	DNA recombination
LDO79_RS09545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LDO79_RS09560	COG0302	gtp cyclohydrolase
LDO79_RS09590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LDO79_RS09600	COG0395	ABC-type sugar transport system, permease component
LDO79_RS09615	COG1131	(ABC) transporter
LDO79_RS09635	COG0556	nucleotide-excision repair
LDO79_RS09640	COG0497	DNA recombination
LDO79_RS09655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LDO79_RS09665	COG0445	tRNA wobble uridine modification
LDO79_RS09685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LDO79_RS09685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDO79_RS09690	COG1543	Belongs to the glycosyl hydrolase 57 family
LDO79_RS09695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LDO79_RS09700	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LDO79_RS09715	COG0189	ligase activity
LDO79_RS09730	COG0066	3-isopropylmalate dehydratase activity
LDO79_RS09735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LDO79_RS09750	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDO79_RS09755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LDO79_RS09760	COG1960	acyl-CoA dehydrogenase activity
LDO79_RS09765	COG0163	prenyltransferase activity
LDO79_RS09810	COG4555	ABC transporter
LDO79_RS09820	COG2096	Adenosyltransferase
LDO79_RS09840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LDO79_RS09845	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LDO79_RS09855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LDO79_RS09860	COG0723	plastoquinol--plastocyanin reductase activity
LDO79_RS09885	COG1653	transport
LDO79_RS09890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LDO79_RS09895	COG1960	acyl-CoA dehydrogenase activity
LDO79_RS09905	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LDO79_RS09925	COG0393	Putative heavy-metal-binding
LDO79_RS09935	COG3956	TIGRFAM MazG family protein
LDO79_RS09940	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LDO79_RS09960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LDO79_RS09970	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LDO79_RS09975	COG1937	Protein conserved in bacteria
LDO79_RS09985	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LDO79_RS09985	COG0674	pyruvate-flavodoxin oxidoreductase activity
LDO79_RS09990	COG1013	pyruvate-flavodoxin oxidoreductase activity
LDO79_RS09995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDO79_RS10015	COG0205	6-phosphofructokinase activity
LDO79_RS10020	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LDO79_RS10030	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LDO79_RS10045	COG2333	competence protein COMEC
LDO79_RS10045	COG0658	competence protein
LDO79_RS10050	COG1475	DNA binding
LDO79_RS10055	COG1192	Involved in chromosome partitioning
LDO79_RS10060	COG0357	Ribosomal RNA small subunit methyltransferase G
LDO79_RS10115	COG1110	DNA topoisomerase II activity
LDO79_RS10120	COG4565	transcriptional regulatory protein
LDO79_RS10135	COG3842	ATPase activity
LDO79_RS10215	COG1857	crispr-associated protein
LDO79_RS10235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LDO79_RS10245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LDO79_RS10295	COG1607	acyl-coa hydrolase
LDO79_RS10305	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDO79_RS10345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LDO79_RS10355	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LDO79_RS10360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDO79_RS10365	COG4558	Periplasmic binding protein
LDO79_RS10375	COG2329	Antibiotic biosynthesis monooxygenase
LDO79_RS10480	COG1942	4-Oxalocrotonate Tautomerase
LDO79_RS10500	COG2084	Dehydrogenase
LDO79_RS10575	COG0588	phosphoglycerate mutase activity
LDO79_RS10595	COG1028	Short-chain dehydrogenase reductase Sdr
LDO79_RS10600	COG0318	PFAM AMP-dependent synthetase and ligase
LDO79_RS10610	COG2030	dehydratase
LDO79_RS10610	COG1012	belongs to the aldehyde dehydrogenase family
LDO79_RS10615	COG1028	Short-chain dehydrogenase reductase Sdr
LDO79_RS10625	COG1960	acyl-CoA dehydrogenase activity
LDO79_RS10695	COG2211	Major facilitator Superfamily
LDO79_RS10725	COG1797	cobyrinic acid a,c-diamide synthase activity
LDO79_RS10730	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LDO79_RS10740	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LDO79_RS10755	COG0588	phosphoglycerate mutase activity
LDO79_RS10760	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LDO79_RS10765	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
LDO79_RS10810	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDO79_RS10810	COG1648	precorrin-2 dehydrogenase activity
LDO79_RS10815	COG0778	Nitroreductase
LDO79_RS10835	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LDO79_RS10840	COG1492	cobalamin metabolic process
LDO79_RS10845	COG1785	Belongs to the alkaline phosphatase family
LDO79_RS10875	COG1414	Transcriptional regulator
LDO79_RS10880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LDO79_RS10890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LDO79_RS10895	COG1028	Short-chain dehydrogenase reductase Sdr
LDO79_RS10910	COG1028	Short-chain dehydrogenase reductase Sdr
LDO79_RS10925	COG1175	transmembrane transport
LDO79_RS10945	COG2723	6-phospho-beta-galactosidase activity
LDO79_RS10950	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LDO79_RS10970	COG1233	COG1233 Phytoene dehydrogenase and related
LDO79_RS10975	COG0702	epimerase
LDO79_RS11015	COG1562	ergosterol biosynthetic process
LDO79_RS11025	COG2124	cytochrome p450
LDO79_RS11060	COG1304	FMN binding
LDO79_RS11080	COG1085	galactose-1-phosphate uridylyltransferase
LDO79_RS11085	COG3345	alpha-galactosidase
LDO79_RS11110	COG4966	pilus assembly protein PilW
LDO79_RS11140	COG1475	DNA binding
LDO79_RS11145	COG1192	Involved in chromosome partitioning
LDO79_RS11155	COG0243	molybdopterin cofactor binding
LDO79_RS11220	COG2151	metal-sulfur cluster biosynthetic enzyme
LDO79_RS11230	COG2814	Major facilitator Superfamily
LDO79_RS11240	COG0584	glycerophosphoryl diester phosphodiesterase
LDO79_RS11250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LDO79_RS11275	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LDO79_RS11290	COG1337	RAMP superfamily
LDO79_RS11425	COG1073	alpha beta
LDO79_RS11480	COG0863	Belongs to the N(4) N(6)-methyltransferase family