locus-tag	class	description
TTJL18_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TTJL18_RS00015	COG0592	DNA-directed DNA polymerase activity
TTJL18_RS00020	COG0148	phosphopyruvate hydratase activity
TTJL18_RS00025	COG0469	pyruvate kinase activity
TTJL18_RS00035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TTJL18_RS00040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TTJL18_RS00050	COG1842	Phage shock protein A
TTJL18_RS00085	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TTJL18_RS00090	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TTJL18_RS00100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
TTJL18_RS00105	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
TTJL18_RS00110	COG1496	oxidoreductase activity
TTJL18_RS00115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TTJL18_RS00120	COG1278	Cold shock
TTJL18_RS00135	COG1653	transport
TTJL18_RS00150	COG0033	Phosphoglucomutase
TTJL18_RS00165	COG2814	Major facilitator Superfamily
TTJL18_RS00175	COG0517	IMP dehydrogenase activity
TTJL18_RS00175	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TTJL18_RS00180	COG1950	PFAM Membrane protein of
TTJL18_RS00185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TTJL18_RS00195	COG0181	hydroxymethylbilane synthase activity
TTJL18_RS00205	COG0285	dihydrofolate synthase activity
TTJL18_RS00210	COG0436	Aminotransferase
TTJL18_RS00215	COG0521	Mo-molybdopterin cofactor biosynthetic process
TTJL18_RS00240	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TTJL18_RS00245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TTJL18_RS00250	COG1993	acr, cog1993
TTJL18_RS00255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TTJL18_RS00265	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TTJL18_RS00275	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
TTJL18_RS00280	COG1335	isochorismatase
TTJL18_RS00285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TTJL18_RS00300	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
TTJL18_RS00305	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
TTJL18_RS00325	COG1660	Displays ATPase and GTPase activities
TTJL18_RS00330	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TTJL18_RS00375	COG1845	cytochrome c oxidase, subunit III
TTJL18_RS00375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TTJL18_RS00380	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TTJL18_RS00380	COG2010	Cytochrome c
TTJL18_RS00385	COG1612	heme a metabolic process
TTJL18_RS00385	COG0109	protoheme IX farnesyltransferase activity
TTJL18_RS00400	COG0343	queuine tRNA-ribosyltransferase activity
TTJL18_RS00405	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TTJL18_RS00410	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
TTJL18_RS00465	COG1940	carbohydrate kinase activity
TTJL18_RS00475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TTJL18_RS00480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TTJL18_RS00485	COG0589	response to stress
TTJL18_RS00490	COG1611	Belongs to the LOG family
TTJL18_RS00500	COG1011	Hydrolase
TTJL18_RS00505	COG0632	four-way junction helicase activity
TTJL18_RS00510	COG1024	Enoyl-CoA hydratase
TTJL18_RS00520	COG0508	dehydrogenase complex catalyzes the overall conversion of
TTJL18_RS00530	COG1404	Belongs to the peptidase S8 family
TTJL18_RS00540	COG0137	argininosuccinate synthase activity
TTJL18_RS00545	COG0165	Argininosuccinate lyase
TTJL18_RS00565	COG0505	Belongs to the CarA family
TTJL18_RS00575	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
TTJL18_RS00580	COG0166	Belongs to the GPI family
TTJL18_RS00590	COG0714	Associated with various cellular activities
TTJL18_RS00605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TTJL18_RS00610	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TTJL18_RS00615	COG0459	protein refolding
TTJL18_RS00620	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TTJL18_RS00625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
TTJL18_RS00635	COG0778	Nitroreductase
TTJL18_RS00640	COG0791	NLP P60 protein
TTJL18_RS00640	COG1388	LysM domain
TTJL18_RS00650	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TTJL18_RS00655	COG2814	Major facilitator Superfamily
TTJL18_RS00660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TTJL18_RS00670	COG0573	inorganic phosphate transmembrane transporter activity
TTJL18_RS00675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TTJL18_RS00680	COG0482	sulfurtransferase activity
TTJL18_RS00690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TTJL18_RS00695	COG0735	belongs to the Fur family
TTJL18_RS00710	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TTJL18_RS00735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TTJL18_RS00740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TTJL18_RS00745	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TTJL18_RS00750	COG0250	Participates in transcription elongation, termination and antitermination
TTJL18_RS00775	COG0629	single-stranded DNA binding
TTJL18_RS00780	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TTJL18_RS00785	COG0359	binds to the 23S rRNA
TTJL18_RS00795	COG0300	oxidoreductase activity
TTJL18_RS00800	COG0321	lipoyl(octanoyl) transferase activity
TTJL18_RS00805	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TTJL18_RS00860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TTJL18_RS00870	COG1598	PFAM Uncharacterised protein family UPF0150
TTJL18_RS00875	COG0022	dehydrogenase e1 component
TTJL18_RS00880	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TTJL18_RS00885	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
TTJL18_RS00910	COG2226	methyltransferase
TTJL18_RS00915	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TTJL18_RS00925	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
TTJL18_RS00930	COG1187	pseudouridine synthase activity
TTJL18_RS00940	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TTJL18_RS00945	COG0686	Belongs to the AlaDH PNT family
TTJL18_RS00955	COG1461	Dihydroxyacetone kinase
TTJL18_RS00970	COG4591	ABC-type transport system involved in lipoprotein release permease component
TTJL18_RS00975	COG0222	ribosome binding
TTJL18_RS00980	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TTJL18_RS01000	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
TTJL18_RS01015	COG0697	spore germination
TTJL18_RS01030	COG0243	molybdopterin cofactor binding
TTJL18_RS01035	COG2272	Belongs to the type-B carboxylesterase lipase family
TTJL18_RS01040	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TTJL18_RS01050	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TTJL18_RS01080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TTJL18_RS01090	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TTJL18_RS01120	COG0508	dehydrogenase complex catalyzes the overall conversion of
TTJL18_RS01125	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
TTJL18_RS01130	COG0583	DNA-binding transcription factor activity
TTJL18_RS01135	COG0631	protein serine/threonine phosphatase activity
TTJL18_RS01140	COG0105	UTP biosynthetic process
TTJL18_RS01170	COG1278	Cold shock
TTJL18_RS01175	COG0484	heat shock protein binding
TTJL18_RS01180	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TTJL18_RS01185	COG1968	undecaprenyl-diphosphatase activity
TTJL18_RS01190	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TTJL18_RS01195	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TTJL18_RS01210	COG1309	transcriptional regulator
TTJL18_RS01215	COG4242	Belongs to the peptidase S51 family
TTJL18_RS01230	COG0802	atpase or kinase
TTJL18_RS01240	COG0539	negative regulation of cytoplasmic translation
TTJL18_RS01245	COG0495	leucyl-tRNA aminoacylation
TTJL18_RS01310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TTJL18_RS01315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TTJL18_RS01320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TTJL18_RS01325	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TTJL18_RS01350	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
TTJL18_RS01385	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TTJL18_RS01390	COG0825	malonyl-CoA metabolic process
TTJL18_RS01405	COG0437	4 iron, 4 sulfur cluster binding
TTJL18_RS01440	COG3706	GGDEF domain
TTJL18_RS01445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TTJL18_RS01450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TTJL18_RS01470	COG0438	transferase activity, transferring glycosyl groups
TTJL18_RS01480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TTJL18_RS01485	COG1185	polyribonucleotide nucleotidyltransferase activity
TTJL18_RS01490	COG3118	belongs to the thioredoxin family
TTJL18_RS01495	COG0416	fatty acid biosynthetic process
TTJL18_RS01505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TTJL18_RS01515	COG0284	orotidine-5'-phosphate decarboxylase activity
TTJL18_RS01520	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TTJL18_RS01530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TTJL18_RS01550	COG0822	iron-sulfur transferase activity
TTJL18_RS01555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TTJL18_RS01565	COG2132	Multicopper oxidase
TTJL18_RS01590	COG2226	methyltransferase
TTJL18_RS01605	COG2205	protein histidine kinase activity
TTJL18_RS01610	COG0745	RESPONSE REGULATOR receiver
TTJL18_RS01630	COG2217	Heavy metal translocating P-type atpase
TTJL18_RS01635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TTJL18_RS01645	COG0668	transmembrane transport
TTJL18_RS01650	COG3253	May function as heme-dependent peroxidase
TTJL18_RS01655	COG0432	Pfam Uncharacterised protein family UPF0047
TTJL18_RS01670	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
TTJL18_RS01700	COG1489	DNA binding
TTJL18_RS01720	COG1115	amino acid carrier protein
TTJL18_RS01730	COG0442	prolyl-tRNA aminoacylation
TTJL18_RS01745	COG0049	tRNA binding
TTJL18_RS01750	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TTJL18_RS01755	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TTJL18_RS01760	COG0051	transcription antitermination factor activity, RNA binding
TTJL18_RS01770	COG0088	Forms part of the polypeptide exit tunnel
TTJL18_RS01775	COG0089	rRNA binding
TTJL18_RS01780	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TTJL18_RS01785	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TTJL18_RS01795	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TTJL18_RS01800	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TTJL18_RS01805	COG0255	Belongs to the universal ribosomal protein uL29 family
TTJL18_RS01830	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TTJL18_RS01835	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TTJL18_RS01840	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TTJL18_RS01865	COG0201	protein transport
TTJL18_RS01870	COG0563	adenylate kinase activity
TTJL18_RS01880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TTJL18_RS01890	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TTJL18_RS01895	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TTJL18_RS01900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TTJL18_RS01905	COG0202	RNA polymerase activity
TTJL18_RS01910	COG0203	ribosomal protein L17
TTJL18_RS01940	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TTJL18_RS01955	COG0142	geranyltranstransferase activity
TTJL18_RS01960	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TTJL18_RS01995	COG0366	Alpha amylase catalytic
TTJL18_RS02000	COG1193	negative regulation of DNA recombination
TTJL18_RS02005	COG1611	Belongs to the LOG family
TTJL18_RS02010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TTJL18_RS02015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TTJL18_RS02020	COG3706	GGDEF domain
TTJL18_RS02025	COG1166	arginine decarboxylase activity
TTJL18_RS02040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TTJL18_RS02045	COG0006	proline dipeptidase activity
TTJL18_RS02055	COG0747	negative chemotaxis
TTJL18_RS02060	COG0601	transmembrane transport
TTJL18_RS02065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TTJL18_RS02070	COG0101	tRNA pseudouridine synthase activity
TTJL18_RS02075	COG3842	ATPase activity
TTJL18_RS02085	COG1840	ABC-type Fe3 transport system, periplasmic component
TTJL18_RS02100	COG1764	response to oxidative stress
TTJL18_RS02110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TTJL18_RS02115	COG2897	thiosulfate sulfurtransferase activity
TTJL18_RS02120	COG0071	Belongs to the small heat shock protein (HSP20) family
TTJL18_RS02125	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
TTJL18_RS02130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TTJL18_RS02135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TTJL18_RS02140	COG0537	adenosine 5'-monophosphoramidase activity
TTJL18_RS02165	COG1011	Hydrolase
TTJL18_RS02170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TTJL18_RS02190	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TTJL18_RS02195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TTJL18_RS02200	COG1506	peptidase
TTJL18_RS02200	COG4946	Tricorn protease homolog
TTJL18_RS02200	COG0823	Involved in the tonB-independent uptake of proteins
TTJL18_RS02225	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TTJL18_RS02230	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TTJL18_RS02235	COG0113	porphobilinogen synthase activity
TTJL18_RS02250	COG0631	protein serine/threonine phosphatase activity
TTJL18_RS02255	COG0515	serine threonine protein kinase
TTJL18_RS02255	COG2815	serine threonine protein kinase
TTJL18_RS02280	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TTJL18_RS02285	COG0193	aminoacyl-tRNA hydrolase activity
TTJL18_RS02290	COG1181	Belongs to the D-alanine--D-alanine ligase family
TTJL18_RS02295	COG0187	DNA topoisomerase II activity
TTJL18_RS02310	COG0827	DNA restriction-modification system
TTJL18_RS02310	COG0732	type I restriction modification DNA specificity domain
TTJL18_RS02315	COG0156	8-amino-7-oxononanoate synthase activity
TTJL18_RS02330	COG0506	proline dehydrogenase activity
TTJL18_RS02335	COG1012	belongs to the aldehyde dehydrogenase family
TTJL18_RS02340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TTJL18_RS02345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TTJL18_RS02375	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
TTJL18_RS02385	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
TTJL18_RS02390	COG2385	sporulation resulting in formation of a cellular spore
TTJL18_RS02395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TTJL18_RS02405	COG0194	GDP metabolic process
TTJL18_RS02410	COG1758	RNA polymerase activity
TTJL18_RS02415	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TTJL18_RS02420	COG1438	arginine binding
TTJL18_RS02425	COG2095	MarC family integral membrane protein
TTJL18_RS02430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TTJL18_RS02435	COG0328	RNA-DNA hybrid ribonuclease activity
TTJL18_RS02445	COG4274	PFAM GYD family protein
TTJL18_RS02450	COG4636	protein conserved in cyanobacteria
TTJL18_RS02455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TTJL18_RS02455	COG0519	Catalyzes the synthesis of GMP from XMP
TTJL18_RS02470	COG1854	S-ribosylhomocysteine lyase activity
TTJL18_RS02475	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TTJL18_RS02480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TTJL18_RS02485	COG0322	excinuclease ABC activity
TTJL18_RS02495	COG2050	protein possibly involved in aromatic compounds catabolism
TTJL18_RS02535	COG0538	isocitrate dehydrogenase activity
TTJL18_RS02540	COG0557	exoribonuclease II activity
TTJL18_RS02555	COG0585	pseudouridine synthase activity
TTJL18_RS02575	COG0604	alcohol dehydrogenase
TTJL18_RS02585	COG0497	DNA recombination
TTJL18_RS02590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TTJL18_RS02605	COG0116	Belongs to the methyltransferase superfamily
TTJL18_RS02610	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TTJL18_RS02615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TTJL18_RS02625	COG0047	phosphoribosylformylglycinamidine synthase activity
TTJL18_RS02635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TTJL18_RS02650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TTJL18_RS02675	COG1011	Hydrolase
TTJL18_RS02690	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TTJL18_RS02705	COG3850	Histidine kinase
TTJL18_RS02705	COG5002	protein histidine kinase activity
TTJL18_RS02715	COG1272	protein, Hemolysin III
TTJL18_RS02720	COG0574	Belongs to the PEP-utilizing enzyme family
TTJL18_RS02720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TTJL18_RS02725	COG0714	Associated with various cellular activities
TTJL18_RS02730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TTJL18_RS02735	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
TTJL18_RS02750	COG0616	signal peptide processing
TTJL18_RS02760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TTJL18_RS02765	COG0443	Heat shock 70 kDa protein
TTJL18_RS02770	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TTJL18_RS02775	COG0484	heat shock protein binding
TTJL18_RS02780	COG0789	Transcriptional regulator
TTJL18_RS02785	COG0542	response to heat
TTJL18_RS02825	COG3118	belongs to the thioredoxin family
TTJL18_RS02845	COG0490	domain, Protein
TTJL18_RS02850	COG0475	glutathione-regulated potassium exporter activity
TTJL18_RS02865	COG0517	IMP dehydrogenase activity
TTJL18_RS02865	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TTJL18_RS02865	COG0617	tRNA 3'-terminal CCA addition
TTJL18_RS02870	COG0475	glutathione-regulated potassium exporter activity
TTJL18_RS02880	COG0305	Participates in initiation and elongation during chromosome replication
TTJL18_RS02885	COG0840	transmembrane signaling receptor activity
TTJL18_RS02890	COG0069	glutamate synthase activity
TTJL18_RS02890	COG0070	glutamate synthase
TTJL18_RS02890	COG0067	glutamate synthase
TTJL18_RS02905	COG0504	CTP synthase activity
TTJL18_RS02910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TTJL18_RS02915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TTJL18_RS02920	COG0318	PFAM AMP-dependent synthetase and ligase
TTJL18_RS02950	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TTJL18_RS02955	COG2009	succinate dehydrogenase
TTJL18_RS02970	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TTJL18_RS02975	COG0017	Asparaginyl-tRNA synthetase
TTJL18_RS02990	COG0084	hydrolase, TatD family'
TTJL18_RS02995	COG0427	acetyl-CoA hydrolase
TTJL18_RS03000	COG0686	Belongs to the AlaDH PNT family
TTJL18_RS03005	COG1494	fructose-1,6-bisphosphatase
TTJL18_RS03010	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TTJL18_RS03010	COG0140	phosphoribosyl-ATP diphosphatase activity
TTJL18_RS03015	COG0107	imidazoleglycerol-phosphate synthase activity
TTJL18_RS03025	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
TTJL18_RS03035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TTJL18_RS03045	COG2045	Belongs to the ComB family
TTJL18_RS03050	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TTJL18_RS03055	COG1136	(ABC) transporter
TTJL18_RS03060	COG0813	purine-nucleoside phosphorylase activity
TTJL18_RS03065	COG1024	Enoyl-CoA hydratase
TTJL18_RS03080	COG3360	Dodecin
TTJL18_RS03085	COG0318	PFAM AMP-dependent synthetase and ligase
TTJL18_RS03115	COG3842	ATPase activity
TTJL18_RS03120	COG2010	Cytochrome c
TTJL18_RS03140	COG3258	Cytochrome c
TTJL18_RS03145	COG2010	Cytochrome c
TTJL18_RS03150	COG0737	Belongs to the 5'-nucleotidase family
TTJL18_RS03155	COG2010	Cytochrome c
TTJL18_RS03160	COG3258	Cytochrome c
TTJL18_RS03175	COG0446	pyridine nucleotide-disulphide oxidoreductase
TTJL18_RS03185	COG3258	Cytochrome c
TTJL18_RS03190	COG0785	Cytochrome C biogenesis protein
TTJL18_RS03195	COG4133	protoheme IX ABC transporter activity
TTJL18_RS03200	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TTJL18_RS03205	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TTJL18_RS03210	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
TTJL18_RS03215	COG1138	Cytochrome C-type biogenesis protein
TTJL18_RS03220	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TTJL18_RS03225	COG3088	subunit of a heme lyase
TTJL18_RS03225	COG4235	cytochrome complex assembly
TTJL18_RS03235	COG0723	plastoquinol--plastocyanin reductase activity
TTJL18_RS03240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TTJL18_RS03250	COG0268	Binds directly to 16S ribosomal RNA
TTJL18_RS03265	COG0083	homoserine kinase activity
TTJL18_RS03270	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TTJL18_RS03270	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TTJL18_RS03275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TTJL18_RS03280	COG1160	GTP binding
TTJL18_RS03295	COG0736	holo-[acyl-carrier-protein] synthase activity
TTJL18_RS03300	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
TTJL18_RS03300	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TTJL18_RS03305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TTJL18_RS03310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TTJL18_RS03315	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TTJL18_RS03320	COG1450	Type ii and iii secretion system protein
TTJL18_RS03345	COG0473	3-isopropylmalate dehydrogenase activity
TTJL18_RS03375	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
TTJL18_RS03400	COG1752	Esterase of the alpha-beta hydrolase superfamily
TTJL18_RS03405	COG0681	Belongs to the peptidase S26 family
TTJL18_RS03410	COG1556	Lactate utilization protein
TTJL18_RS03415	COG1139	Iron-sulfur cluster binding protein
TTJL18_RS03420	COG0247	lactate metabolic process
TTJL18_RS03425	COG2205	protein histidine kinase activity
TTJL18_RS03445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TTJL18_RS03460	COG1324	tolerance protein
TTJL18_RS03465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TTJL18_RS03470	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TTJL18_RS03475	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TTJL18_RS03480	COG2197	response regulator
TTJL18_RS03495	COG0776	regulation of translation
TTJL18_RS03505	COG1515	deoxyribonuclease V activity
TTJL18_RS03515	COG1482	cell wall glycoprotein biosynthetic process
TTJL18_RS03520	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TTJL18_RS03525	COG0372	Belongs to the citrate synthase family
TTJL18_RS03530	COG1132	(ABC) transporter
TTJL18_RS03535	COG1132	(ABC) transporter
TTJL18_RS03540	COG0285	dihydrofolate synthase activity
TTJL18_RS03550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TTJL18_RS03555	COG0601	transmembrane transport
TTJL18_RS03560	COG0747	negative chemotaxis
TTJL18_RS03580	COG0559	Belongs to the binding-protein-dependent transport system permease family
TTJL18_RS03590	COG0174	glutamine synthetase
TTJL18_RS03595	COG0737	Belongs to the 5'-nucleotidase family
TTJL18_RS03615	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TTJL18_RS03620	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TTJL18_RS03625	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
TTJL18_RS03630	COG0788	formyltetrahydrofolate deformylase activity
TTJL18_RS03635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TTJL18_RS03650	COG2358	TRAP transporter, solute receptor (TAXI family
TTJL18_RS03660	COG2358	TRAP transporter, solute receptor (TAXI family
TTJL18_RS03665	COG1994	Peptidase M50
TTJL18_RS03665	COG0517	IMP dehydrogenase activity
TTJL18_RS03675	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TTJL18_RS03680	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TTJL18_RS03685	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TTJL18_RS03705	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TTJL18_RS03720	COG0746	molybdenum cofactor guanylyltransferase activity
TTJL18_RS03725	COG1129	ABC transporter
TTJL18_RS03730	COG4603	Belongs to the binding-protein-dependent transport system permease family
TTJL18_RS03735	COG1079	Belongs to the binding-protein-dependent transport system permease family
TTJL18_RS03745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TTJL18_RS03750	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TTJL18_RS03755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TTJL18_RS03755	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TTJL18_RS03760	COG0793	Belongs to the peptidase S41A family
TTJL18_RS03765	COG2884	Cell division ATP-binding protein ftsE
TTJL18_RS03770	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
TTJL18_RS03790	COG0420	3'-5' exonuclease activity
TTJL18_RS03795	COG0419	ATPase involved in DNA repair
TTJL18_RS03805	COG0728	peptidoglycan biosynthetic process
TTJL18_RS03815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TTJL18_RS03825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TTJL18_RS03850	COG1269	ATP hydrolysis coupled proton transport
TTJL18_RS03860	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
TTJL18_RS03865	COG1527	subunit (C
TTJL18_RS03870	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
TTJL18_RS03875	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TTJL18_RS03880	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TTJL18_RS03885	COG1394	ATPase activity, coupled to movement of substances
TTJL18_RS03900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TTJL18_RS03905	COG0612	Peptidase, M16
TTJL18_RS03910	COG0612	Peptidase, M16
TTJL18_RS03915	COG0697	spore germination
TTJL18_RS03920	COG1250	3-hydroxyacyl-CoA dehydrogenase
TTJL18_RS03930	COG0358	DNA primase activity
TTJL18_RS03945	COG1111	helicase
TTJL18_RS03945	COG1205	dead DEAH box helicase
TTJL18_RS03950	COG0393	Putative heavy-metal-binding
TTJL18_RS03970	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TTJL18_RS03975	COG0653	protein targeting
TTJL18_RS03980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TTJL18_RS03985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TTJL18_RS03990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TTJL18_RS04000	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TTJL18_RS04000	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TTJL18_RS04010	COG1733	regulation of RNA biosynthetic process
TTJL18_RS04015	COG2894	cell division
TTJL18_RS04020	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
TTJL18_RS04025	COG0772	Belongs to the SEDS family
TTJL18_RS04030	COG3842	ATPase activity
TTJL18_RS04035	COG1176	ABC-type spermidine putrescine transport system, permease component I
TTJL18_RS04040	COG1177	transmembrane transport
TTJL18_RS04045	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
TTJL18_RS04055	COG0129	dihydroxy-acid dehydratase activity
TTJL18_RS04060	COG0300	oxidoreductase activity
TTJL18_RS04075	COG0473	3-isopropylmalate dehydrogenase activity
TTJL18_RS04080	COG0066	3-isopropylmalate dehydratase activity
TTJL18_RS04085	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TTJL18_RS04100	COG0544	peptidyl-prolyl cis-trans isomerase activity
TTJL18_RS04105	COG4974	Belongs to the 'phage' integrase family
TTJL18_RS04115	COG0180	Tryptophanyl-tRNA synthetase
TTJL18_RS04140	COG2165	general secretion pathway protein
TTJL18_RS04150	COG4966	pilus assembly protein PilW
TTJL18_RS04155	COG2165	general secretion pathway protein
TTJL18_RS04160	COG4970	Tfp pilus assembly protein FimT
TTJL18_RS04165	COG4970	Tfp pilus assembly protein FimT
TTJL18_RS04170	COG0492	ferredoxin-NADP+ reductase activity
TTJL18_RS04175	COG0028	Belongs to the TPP enzyme family
TTJL18_RS04180	COG0440	acetolactate synthase activity
TTJL18_RS04185	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TTJL18_RS04200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TTJL18_RS04215	COG1131	(ABC) transporter
TTJL18_RS04245	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TTJL18_RS04265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TTJL18_RS04275	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TTJL18_RS04280	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TTJL18_RS04305	COG0850	regulation of cytokinetic process
TTJL18_RS04310	COG0768	penicillin binding
TTJL18_RS04325	COG0424	maF-like protein
TTJL18_RS04335	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TTJL18_RS04340	COG0012	GTP binding
TTJL18_RS04360	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
TTJL18_RS04365	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
TTJL18_RS04375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TTJL18_RS04380	COG3001	Fructosamine kinase
TTJL18_RS04390	COG2313	pseudouridylate synthase activity
TTJL18_RS04395	COG1426	Protein conserved in bacteria
TTJL18_RS04400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TTJL18_RS04405	COG0569	domain protein
TTJL18_RS04410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TTJL18_RS04420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TTJL18_RS04425	COG0765	amino acid transport
TTJL18_RS04430	COG0525	valine-tRNA ligase activity
TTJL18_RS04440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TTJL18_RS04450	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TTJL18_RS04455	COG0134	indole-3-glycerol-phosphate synthase activity
TTJL18_RS04460	COG1752	Esterase of the alpha-beta hydrolase superfamily
TTJL18_RS04480	COG2358	TRAP transporter, solute receptor (TAXI family
TTJL18_RS04485	COG2873	o-acetylhomoserine
TTJL18_RS04505	COG2309	aminopeptidase activity
TTJL18_RS04515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TTJL18_RS04515	COG1796	DNA polymerase
TTJL18_RS04520	COG1573	uracil-dna glycosylase
TTJL18_RS04525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TTJL18_RS04535	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TTJL18_RS04540	COG2086	electron transfer activity
TTJL18_RS04545	COG1960	acyl-CoA dehydrogenase activity
TTJL18_RS04550	COG5002	protein histidine kinase activity
TTJL18_RS04555	COG0745	RESPONSE REGULATOR receiver
TTJL18_RS04560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TTJL18_RS04565	COG0517	IMP dehydrogenase activity
TTJL18_RS04565	COG0617	tRNA 3'-terminal CCA addition
TTJL18_RS04565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TTJL18_RS04575	COG0589	response to stress
TTJL18_RS04580	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TTJL18_RS04585	COG1185	polyribonucleotide nucleotidyltransferase activity
TTJL18_RS04590	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TTJL18_RS04595	COG2814	Major facilitator Superfamily
TTJL18_RS04605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TTJL18_RS04610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TTJL18_RS04620	COG1100	Small GTP-binding protein
TTJL18_RS04635	COG0010	Belongs to the arginase family
TTJL18_RS04655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TTJL18_RS04660	COG0511	ligase activity, forming carbon-carbon bonds
TTJL18_RS04665	COG0439	Biotin carboxylase
TTJL18_RS04675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TTJL18_RS04680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TTJL18_RS04685	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
TTJL18_RS04695	COG0247	lactate metabolic process
TTJL18_RS04695	COG2181	nitrate reductase activity
TTJL18_RS04705	COG0861	Integral membrane protein TerC family
TTJL18_RS04710	COG2819	hydrolase of the alpha beta superfamily
TTJL18_RS04715	COG0039	L-malate dehydrogenase activity
TTJL18_RS04725	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TTJL18_RS04730	COG0438	transferase activity, transferring glycosyl groups
TTJL18_RS04780	COG3845	ABC transporter
TTJL18_RS04785	COG1744	ABC transporter substrate-binding protein PnrA-like
TTJL18_RS04790	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TTJL18_RS04795	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TTJL18_RS04800	COG0133	tryptophan synthase activity
TTJL18_RS04805	COG0159	tryptophan synthase activity
TTJL18_RS04815	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TTJL18_RS04830	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TTJL18_RS04850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TTJL18_RS04855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TTJL18_RS04860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TTJL18_RS04865	COG0772	Belongs to the SEDS family
TTJL18_RS04870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TTJL18_RS04875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TTJL18_RS04885	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TTJL18_RS04890	COG0768	penicillin binding
TTJL18_RS04900	COG0275	rRNA processing
TTJL18_RS04905	COG2001	Belongs to the MraZ family
TTJL18_RS04915	COG0254	rRNA binding
TTJL18_RS04920	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TTJL18_RS04930	COG0739	heme binding
TTJL18_RS04940	COG0006	proline dipeptidase activity
TTJL18_RS04945	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TTJL18_RS04950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TTJL18_RS04955	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TTJL18_RS04960	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TTJL18_RS04960	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TTJL18_RS04970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TTJL18_RS04970	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TTJL18_RS04975	COG2304	oxidoreductase activity
TTJL18_RS04980	COG2239	Acts as a magnesium transporter
TTJL18_RS04990	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TTJL18_RS05000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TTJL18_RS05005	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TTJL18_RS05005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TTJL18_RS05025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TTJL18_RS05035	COG4864	UPF0365 protein
TTJL18_RS05045	COG1702	phosphate starvation-inducible protein PhoH
TTJL18_RS05050	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TTJL18_RS05055	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
TTJL18_RS05065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TTJL18_RS05075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TTJL18_RS05080	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TTJL18_RS05080	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TTJL18_RS05085	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TTJL18_RS05100	COG0228	four-way junction DNA binding
TTJL18_RS05105	COG1837	Belongs to the UPF0109 family
TTJL18_RS05110	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TTJL18_RS05115	COG0336	Belongs to the RNA methyltransferase TrmD family
TTJL18_RS05120	COG0335	large ribosomal subunit rRNA binding
TTJL18_RS05125	COG2197	response regulator
TTJL18_RS05130	COG1760	l-serine dehydratase
TTJL18_RS05135	COG2897	thiosulfate sulfurtransferase activity
TTJL18_RS05165	COG0842	Transport permease protein
TTJL18_RS05170	COG1131	(ABC) transporter
TTJL18_RS05175	COG1309	transcriptional regulator
TTJL18_RS05180	COG0577	efflux transmembrane transporter activity
TTJL18_RS05180	COG1136	(ABC) transporter
TTJL18_RS05185	COG1136	(ABC) transporter
TTJL18_RS05190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TTJL18_RS05205	COG2205	protein histidine kinase activity
TTJL18_RS05210	COG0745	RESPONSE REGULATOR receiver
TTJL18_RS05225	COG0210	DNA helicase
TTJL18_RS05230	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TTJL18_RS05235	COG1012	belongs to the aldehyde dehydrogenase family
TTJL18_RS05265	COG1846	Transcriptional regulator
TTJL18_RS05270	COG0477	Major facilitator Superfamily
TTJL18_RS05275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TTJL18_RS05280	COG0183	Belongs to the thiolase family
TTJL18_RS05285	COG1331	Highly conserved protein containing a thioredoxin domain
TTJL18_RS05305	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TTJL18_RS05310	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
TTJL18_RS05320	COG1733	regulation of RNA biosynthetic process
TTJL18_RS05325	COG1980	fructose-bisphosphate aldolase activity
TTJL18_RS05355	COG0395	ABC-type sugar transport system, permease component
TTJL18_RS05365	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
TTJL18_RS05375	COG3396	Phenylacetate-CoA oxygenase
TTJL18_RS05395	COG2030	dehydratase
TTJL18_RS05395	COG1012	belongs to the aldehyde dehydrogenase family
TTJL18_RS05405	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TTJL18_RS05410	COG2050	protein possibly involved in aromatic compounds catabolism
TTJL18_RS05440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TTJL18_RS05445	COG2368	4-hydroxyphenylacetate
TTJL18_RS05450	COG1012	belongs to the aldehyde dehydrogenase family
TTJL18_RS05460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TTJL18_RS05470	COG3769	mannosylglycerate metabolic process
TTJL18_RS05485	COG1136	(ABC) transporter
TTJL18_RS05510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TTJL18_RS05515	COG1307	EDD domain protein, DegV family
TTJL18_RS05520	COG1307	EDD domain protein, DegV family
TTJL18_RS05525	COG1490	D-aminoacyl-tRNA deacylase activity
TTJL18_RS05530	COG3239	Fatty acid desaturase
TTJL18_RS05535	COG0149	triose-phosphate isomerase activity
TTJL18_RS05615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TTJL18_RS05625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TTJL18_RS05630	COG0138	bifunctional purine biosynthesis protein purh
TTJL18_RS05635	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TTJL18_RS05640	COG0742	ribosomal rna small subunit methyltransferase
TTJL18_RS05655	COG0237	dephospho-CoA kinase activity
TTJL18_RS05660	COG0617	tRNA 3'-terminal CCA addition
TTJL18_RS05660	COG1353	crispr-associated protein
TTJL18_RS05665	COG1355	regulation of microtubule-based process
TTJL18_RS05670	COG0557	exoribonuclease II activity
TTJL18_RS05680	COG0824	Thioesterase
TTJL18_RS05685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TTJL18_RS05690	COG0126	phosphoglycerate kinase activity
TTJL18_RS05700	COG1268	BioY protein
TTJL18_RS05705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TTJL18_RS05705	COG3153	acetyltransferase
TTJL18_RS05710	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TTJL18_RS05725	COG1196	nuclear chromosome segregation
TTJL18_RS05740	COG2738	Putative neutral zinc metallopeptidase
TTJL18_RS05750	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
TTJL18_RS05755	COG0215	cysteine-tRNA ligase activity
TTJL18_RS05760	COG1960	acyl-CoA dehydrogenase activity
TTJL18_RS05765	COG0183	Belongs to the thiolase family
TTJL18_RS05770	COG1024	Enoyl-CoA hydratase
TTJL18_RS05770	COG1250	3-hydroxyacyl-CoA dehydrogenase
TTJL18_RS05775	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
TTJL18_RS05785	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
TTJL18_RS05790	COG0438	transferase activity, transferring glycosyl groups
TTJL18_RS05800	COG1216	Glycosyl transferase, family 2
TTJL18_RS05810	COG1215	transferase activity, transferring glycosyl groups
TTJL18_RS05825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TTJL18_RS05825	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
TTJL18_RS05830	COG1811	Na channel or pump
TTJL18_RS05835	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TTJL18_RS05840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TTJL18_RS05845	COG4948	Mandelate Racemase Muconate Lactonizing
TTJL18_RS05855	COG0402	S-adenosylhomocysteine deaminase activity
TTJL18_RS05890	COG0494	nUDIX hydrolase
TTJL18_RS05895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TTJL18_RS05905	COG0052	Belongs to the universal ribosomal protein uS2 family
TTJL18_RS05910	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TTJL18_RS05915	COG0528	UMP kinase activity
TTJL18_RS05920	COG0233	cytoplasmic translational termination
TTJL18_RS05925	COG0575	Belongs to the CDS family
TTJL18_RS05930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TTJL18_RS05935	COG0750	zinc metalloprotease
TTJL18_RS05940	COG0463	Glycosyl transferase, family 2
TTJL18_RS05950	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TTJL18_RS05955	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TTJL18_RS05960	COG2359	stage V sporulation protein S
TTJL18_RS05970	COG2137	regulation of response to DNA damage stimulus
TTJL18_RS05995	COG2766	serine protein kinase
TTJL18_RS06000	COG2718	Belongs to the UPF0229 family
TTJL18_RS06005	COG2719	SpoVR family
TTJL18_RS06010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TTJL18_RS06015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TTJL18_RS06030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TTJL18_RS06040	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
TTJL18_RS06045	COG1994	Peptidase M50
TTJL18_RS06055	COG0617	tRNA 3'-terminal CCA addition
TTJL18_RS06055	COG3620	sequence-specific DNA binding
TTJL18_RS06055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TTJL18_RS06070	COG0517	IMP dehydrogenase activity
TTJL18_RS06085	COG1674	ftsk spoiiie
TTJL18_RS06090	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TTJL18_RS06095	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TTJL18_RS06100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
TTJL18_RS06105	COG4651	solute:proton antiporter activity
TTJL18_RS06105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TTJL18_RS06110	COG0217	transcriptional regulatory protein
TTJL18_RS06120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TTJL18_RS06150	COG2176	DNA-directed DNA polymerase activity
TTJL18_RS06150	COG5002	protein histidine kinase activity
TTJL18_RS06155	COG0151	Belongs to the GarS family
TTJL18_RS06160	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TTJL18_RS06170	COG0179	Fumarylacetoacetate (FAA) hydrolase
TTJL18_RS06175	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TTJL18_RS06215	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TTJL18_RS06220	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
TTJL18_RS06225	COG2353	YceI-like domain
TTJL18_RS06230	COG2514	catechol 2,3-dioxygenase activity
TTJL18_RS06235	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TTJL18_RS06240	COG0287	Prephenate dehydrogenase
TTJL18_RS06250	COG0277	FAD linked oxidase domain protein
TTJL18_RS06265	COG1459	type II secretion system
TTJL18_RS06270	COG0009	L-threonylcarbamoyladenylate synthase
TTJL18_RS06275	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TTJL18_RS06285	COG0456	acetyltransferase
TTJL18_RS06290	COG1960	acyl-CoA dehydrogenase activity
TTJL18_RS06310	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TTJL18_RS06315	COG0730	response to heat
TTJL18_RS06340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TTJL18_RS06350	COG0167	dihydroorotate dehydrogenase activity
TTJL18_RS06360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TTJL18_RS06370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TTJL18_RS06375	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TTJL18_RS06380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TTJL18_RS06385	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TTJL18_RS06395	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TTJL18_RS06410	COG1063	alcohol dehydrogenase
TTJL18_RS06425	COG2873	o-acetylhomoserine
TTJL18_RS06430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TTJL18_RS06445	COG1073	alpha beta
TTJL18_RS06450	COG0405	Gamma-glutamyltransferase
TTJL18_RS06475	COG1028	Short-chain dehydrogenase reductase Sdr
TTJL18_RS06490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TTJL18_RS06510	COG0481	GTPase activity
TTJL18_RS06520	COG1760	l-serine dehydratase
TTJL18_RS06540	COG0295	cytidine deaminase activity
TTJL18_RS06585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TTJL18_RS06595	COG1316	TRANSCRIPTIONal
TTJL18_RS06610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TTJL18_RS06630	COG1573	uracil-dna glycosylase
TTJL18_RS06645	COG3842	ATPase activity
TTJL18_RS06655	COG0124	histidyl-tRNA synthetase
TTJL18_RS06665	COG0384	phenazine biosynthesis protein PhzF
TTJL18_RS06670	COG0561	phosphatase activity
TTJL18_RS06675	COG0017	Asparaginyl-tRNA synthetase
TTJL18_RS06680	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
TTJL18_RS06715	COG0702	epimerase
TTJL18_RS06720	COG1233	COG1233 Phytoene dehydrogenase and related
TTJL18_RS06730	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TTJL18_RS06755	COG0640	Transcriptional regulator
TTJL18_RS06760	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
TTJL18_RS06770	COG0779	Required for maturation of 30S ribosomal subunits
TTJL18_RS06775	COG0195	Participates in both transcription termination and antitermination
TTJL18_RS06785	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TTJL18_RS06795	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TTJL18_RS06795	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TTJL18_RS06810	COG0318	PFAM AMP-dependent synthetase and ligase
TTJL18_RS06815	COG0596	Alpha beta hydrolase
TTJL18_RS06825	COG2030	dehydratase
TTJL18_RS06835	COG0559	Belongs to the binding-protein-dependent transport system permease family
TTJL18_RS06855	COG1028	Short-chain dehydrogenase reductase Sdr
TTJL18_RS06860	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TTJL18_RS06870	COG0183	Belongs to the thiolase family
TTJL18_RS06875	COG1940	carbohydrate kinase activity
TTJL18_RS06885	COG1175	transmembrane transport
TTJL18_RS06920	COG0351	phosphomethylpyrimidine kinase
TTJL18_RS06925	COG0477	Major facilitator Superfamily
TTJL18_RS06930	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TTJL18_RS06940	COG2022	thiamine diphosphate biosynthetic process
TTJL18_RS06945	COG2104	thiamine diphosphate biosynthetic process
TTJL18_RS06950	COG0352	thiamine-phosphate diphosphorylase activity
TTJL18_RS06960	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TTJL18_RS06965	COG1587	Uroporphyrinogen-III synthase
TTJL18_RS06970	COG1648	precorrin-2 dehydrogenase activity
TTJL18_RS06970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TTJL18_RS06975	COG0175	sulfate reduction
TTJL18_RS06980	COG0730	response to heat
TTJL18_RS06985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TTJL18_RS06985	COG1648	precorrin-2 dehydrogenase activity
TTJL18_RS06990	COG2046	Belongs to the sulfate adenylyltransferase family
TTJL18_RS06995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TTJL18_RS07030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TTJL18_RS07035	COG2264	protein methyltransferase activity
TTJL18_RS07045	COG0489	protein tyrosine kinase activity
TTJL18_RS07065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TTJL18_RS07145	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TTJL18_RS07150	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TTJL18_RS07180	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
TTJL18_RS07185	COG1692	metallophosphoesterase
TTJL18_RS07210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TTJL18_RS07220	COG1410	methionine synthase
TTJL18_RS07220	COG0646	methionine synthase
TTJL18_RS07225	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TTJL18_RS07230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TTJL18_RS07235	COG0740	serine-type endopeptidase activity
TTJL18_RS07240	COG0544	peptidyl-prolyl cis-trans isomerase activity
TTJL18_RS07260	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TTJL18_RS07265	COG3870	Protein conserved in bacteria
TTJL18_RS07275	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
TTJL18_RS07280	COG1293	RNA-binding protein homologous to eukaryotic snRNP
TTJL18_RS07285	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TTJL18_RS07300	COG1960	acyl-CoA dehydrogenase activity
TTJL18_RS07305	COG1012	belongs to the aldehyde dehydrogenase family
TTJL18_RS07305	COG2030	dehydratase
TTJL18_RS07310	COG0318	PFAM AMP-dependent synthetase and ligase
TTJL18_RS07315	COG1028	Short-chain dehydrogenase reductase Sdr
TTJL18_RS07330	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TTJL18_RS07335	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
TTJL18_RS07340	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
TTJL18_RS07360	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TTJL18_RS07365	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TTJL18_RS07420	COG4475	Protein of unknown function (DUF436)
TTJL18_RS07435	COG3842	ATPase activity
TTJL18_RS07440	COG0572	uridine kinase
TTJL18_RS07465	COG0154	amidase activity
TTJL18_RS07470	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TTJL18_RS07480	COG2133	pyrroloquinoline quinone binding
TTJL18_RS07485	COG1063	alcohol dehydrogenase
TTJL18_RS07495	COG1254	Belongs to the acylphosphatase family
TTJL18_RS07500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TTJL18_RS07515	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TTJL18_RS07520	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TTJL18_RS07535	COG0183	Belongs to the thiolase family
TTJL18_RS07540	COG0114	fumarate hydratase activity
TTJL18_RS07545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TTJL18_RS07550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TTJL18_RS07555	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TTJL18_RS07565	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TTJL18_RS07575	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TTJL18_RS07585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TTJL18_RS07585	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TTJL18_RS07605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
TTJL18_RS07620	COG0423	glycine-tRNA ligase activity
TTJL18_RS07625	COG0542	response to heat
TTJL18_RS07630	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TTJL18_RS07635	COG4956	integral membrane protein (PIN domain superfamily)
TTJL18_RS07665	COG0527	aspartate kinase activity
TTJL18_RS07670	COG2813	Specifically methylates the guanine in position
TTJL18_RS07675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TTJL18_RS07700	COG0196	riboflavin kinase activity
TTJL18_RS07705	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TTJL18_RS07710	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TTJL18_RS07715	COG0509	glycine decarboxylation via glycine cleavage system
TTJL18_RS07720	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TTJL18_RS07735	COG0281	malic enzyme
TTJL18_RS07740	COG2151	metal-sulfur cluster biosynthetic enzyme
TTJL18_RS07745	COG0861	Integral membrane protein TerC family
TTJL18_RS07780	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TTJL18_RS07785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TTJL18_RS07795	COG0789	Transcriptional regulator
TTJL18_RS07800	COG1414	Transcriptional regulator
TTJL18_RS07805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
TTJL18_RS07810	COG0277	FAD linked oxidase domain protein
TTJL18_RS07815	COG0277	FAD linked oxidase domain protein
TTJL18_RS07820	COG0247	lactate metabolic process
TTJL18_RS07845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TTJL18_RS07890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TTJL18_RS07900	COG0460	homoserine dehydrogenase
TTJL18_RS07910	COG3744	PilT protein domain protein
TTJL18_RS07915	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TTJL18_RS07940	COG2226	methyltransferase
TTJL18_RS07945	COG2226	methyltransferase
TTJL18_RS07950	COG0366	Alpha amylase catalytic
TTJL18_RS07955	COG3448	diguanylate cyclase activity
TTJL18_RS07955	COG4175	Glycine betaine
TTJL18_RS07960	COG4176	ABC-type proline glycine betaine transport system permease component
TTJL18_RS07970	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
TTJL18_RS07985	COG0037	tRNA processing
TTJL18_RS07990	COG2104	thiamine diphosphate biosynthetic process
TTJL18_RS07995	COG0123	including yeast histone deacetylase and acetoin utilization protein
TTJL18_RS08000	COG0517	IMP dehydrogenase activity
TTJL18_RS08015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TTJL18_RS08020	COG0601	transmembrane transport
TTJL18_RS08025	COG0747	negative chemotaxis
TTJL18_RS08030	COG1028	Short-chain dehydrogenase reductase Sdr
TTJL18_RS08030	COG0604	alcohol dehydrogenase
TTJL18_RS08030	COG3321	synthase
TTJL18_RS08035	COG0492	ferredoxin-NADP+ reductase activity
TTJL18_RS08060	COG1028	Short-chain dehydrogenase reductase Sdr
TTJL18_RS08075	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TTJL18_RS08080	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TTJL18_RS08085	COG1104	cysteine desulfurase activity
TTJL18_RS08090	COG1959	2 iron, 2 sulfur cluster binding
TTJL18_RS08095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TTJL18_RS08100	COG1121	(ABC) transporter
TTJL18_RS08125	COG1022	Amp-dependent synthetase and ligase
TTJL18_RS08135	COG0230	Belongs to the bacterial ribosomal protein bL34 family
TTJL18_RS08140	COG0594	ribonuclease P activity
TTJL18_RS08145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TTJL18_RS08150	COG0706	membrane insertase activity
TTJL18_RS08160	COG2890	protein-(glutamine-N5) methyltransferase activity
TTJL18_RS08175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TTJL18_RS08190	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
TTJL18_RS08205	COG0516	GMP reductase activity
TTJL18_RS08205	COG0517	IMP dehydrogenase activity
TTJL18_RS08215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TTJL18_RS08220	COG0131	Imidazoleglycerol-phosphate dehydratase
TTJL18_RS08225	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TTJL18_RS08240	COG0778	Nitroreductase
TTJL18_RS08275	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TTJL18_RS08280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TTJL18_RS08285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TTJL18_RS08295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TTJL18_RS08300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TTJL18_RS08305	COG0232	Belongs to the dGTPase family. Type 2 subfamily
TTJL18_RS08310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TTJL18_RS08315	COG3335	DDE superfamily endonuclease
TTJL18_RS08335	COG0564	pseudouridine synthase activity
TTJL18_RS08340	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TTJL18_RS08345	COG2255	four-way junction helicase activity
TTJL18_RS08375	COG1063	alcohol dehydrogenase
TTJL18_RS08430	COG1605	Chorismate mutase
TTJL18_RS08430	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TTJL18_RS08435	COG0805	protein transport
TTJL18_RS08440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TTJL18_RS08445	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TTJL18_RS08450	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TTJL18_RS08480	COG0395	ABC-type sugar transport system, permease component
TTJL18_RS08485	COG1175	transmembrane transport
TTJL18_RS08500	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TTJL18_RS08505	COG0792	nuclease activity
TTJL18_RS08515	COG0492	ferredoxin-NADP+ reductase activity
TTJL18_RS08520	COG1028	Short-chain dehydrogenase reductase Sdr
TTJL18_RS08540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TTJL18_RS08550	COG0142	geranyltranstransferase activity
TTJL18_RS08565	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TTJL18_RS08570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TTJL18_RS08580	COG0297	glycogen (starch) synthase activity
TTJL18_RS08585	COG2105	PFAM AIG2 family protein
TTJL18_RS08590	COG0745	RESPONSE REGULATOR receiver
TTJL18_RS08600	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TTJL18_RS08605	COG1067	ATP-dependent peptidase activity
TTJL18_RS08630	COG0667	Aldo Keto reductase
TTJL18_RS08660	COG0277	FAD linked oxidase domain protein
TTJL18_RS08670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TTJL18_RS08680	COG0569	domain protein
TTJL18_RS08680	COG0475	glutathione-regulated potassium exporter activity
TTJL18_RS08690	COG0436	Aminotransferase
TTJL18_RS08700	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
TTJL18_RS08705	COG1597	lipid kinase activity
TTJL18_RS08720	COG0123	including yeast histone deacetylase and acetoin utilization protein
TTJL18_RS08730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
TTJL18_RS08740	COG0004	ammonium transporteR
TTJL18_RS08745	COG0347	Belongs to the P(II) protein family
TTJL18_RS08750	COG1420	regulation of RNA biosynthetic process
TTJL18_RS08755	COG0314	molybdopterin synthase activity
TTJL18_RS08770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TTJL18_RS08775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TTJL18_RS08790	COG0277	FAD linked oxidase domain protein
TTJL18_RS08820	COG1126	abc transporter atp-binding protein
TTJL18_RS08825	COG2720	vancomycin resistance protein
TTJL18_RS08835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TTJL18_RS08845	COG0135	phosphoribosylanthranilate isomerase activity
TTJL18_RS08860	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TTJL18_RS08875	COG4712	double-strand break repair protein
TTJL18_RS08885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TTJL18_RS08890	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTJL18_RS08895	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTJL18_RS08900	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTJL18_RS08905	COG0649	NAD binding
TTJL18_RS08910	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
TTJL18_RS08915	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TTJL18_RS08920	COG1034	ATP synthesis coupled electron transport
TTJL18_RS08925	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TTJL18_RS08930	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTJL18_RS08935	COG0839	Belongs to the complex I subunit 6 family
TTJL18_RS08940	COG0713	ATP synthesis coupled electron transport
TTJL18_RS08945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TTJL18_RS08950	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTJL18_RS08955	COG1007	ATP synthesis coupled electron transport
TTJL18_RS08960	COG0018	arginyl-trna synthetase
TTJL18_RS08965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TTJL18_RS08970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TTJL18_RS08985	COG2070	2-Nitropropane dioxygenase
TTJL18_RS09005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TTJL18_RS09025	COG0513	Belongs to the DEAD box helicase family
TTJL18_RS09030	COG0303	'Molybdopterin
TTJL18_RS09050	COG1121	(ABC) transporter
TTJL18_RS09055	COG0442	prolyl-tRNA aminoacylation
TTJL18_RS09060	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TTJL18_RS09065	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TTJL18_RS09085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TTJL18_RS09125	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TTJL18_RS09130	COG0758	DNA mediated transformation
TTJL18_RS09130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TTJL18_RS09135	COG3546	catalase activity
TTJL18_RS09140	COG0583	DNA-binding transcription factor activity
TTJL18_RS09150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TTJL18_RS09155	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TTJL18_RS09160	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
TTJL18_RS09165	COG0717	Belongs to the dCTP deaminase family
TTJL18_RS09180	COG1028	Short-chain dehydrogenase reductase Sdr
TTJL18_RS09185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TTJL18_RS09210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TTJL18_RS09210	COG0515	serine threonine protein kinase
TTJL18_RS09220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TTJL18_RS09230	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TTJL18_RS09235	COG0704	Plays a role in the regulation of phosphate uptake
TTJL18_RS09240	COG4191	Histidine kinase
TTJL18_RS09245	COG0745	RESPONSE REGULATOR receiver
TTJL18_RS09250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TTJL18_RS09260	COG1187	pseudouridine synthase activity
TTJL18_RS09270	COG1459	type II secretion system
TTJL18_RS09300	COG2165	general secretion pathway protein
TTJL18_RS09310	COG2165	general secretion pathway protein
TTJL18_RS09320	COG2414	aldehyde ferredoxin oxidoreductase
TTJL18_RS09345	COG1902	pentaerythritol trinitrate reductase activity
TTJL18_RS09385	COG0315	cyclic pyranopterin monophosphate synthase activity
TTJL18_RS09390	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TTJL18_RS09405	COG0477	Major facilitator Superfamily
TTJL18_RS09410	COG1694	Mazg nucleotide pyrophosphohydrolase
TTJL18_RS09415	COG1803	Methylglyoxal synthase
TTJL18_RS09425	COG0301	tRNA thio-modification
TTJL18_RS09430	COG0154	amidase activity
TTJL18_RS09435	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TTJL18_RS09460	COG2154	pterin-4-alpha-carbinolamine dehydratase
TTJL18_RS09465	COG1607	acyl-coa hydrolase
TTJL18_RS09475	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TTJL18_RS09485	COG1840	ABC-type Fe3 transport system, periplasmic component
TTJL18_RS09500	COG0235	Class ii aldolase
TTJL18_RS09505	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TTJL18_RS09510	COG0085	RNA polymerase activity
TTJL18_RS09520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TTJL18_RS09525	COG1077	Cell shape determining protein MreB Mrl
TTJL18_RS09530	COG1418	mRNA catabolic process
TTJL18_RS09530	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TTJL18_RS09535	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TTJL18_RS09540	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TTJL18_RS09545	COG1546	Belongs to the CinA family
TTJL18_RS09545	COG1058	Belongs to the CinA family
TTJL18_RS09550	COG0354	folic acid binding
TTJL18_RS09565	COG4948	Mandelate Racemase Muconate Lactonizing
TTJL18_RS09580	COG1175	transmembrane transport
TTJL18_RS09590	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
TTJL18_RS09600	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TTJL18_RS09610	COG1136	(ABC) transporter
TTJL18_RS09610	COG0577	efflux transmembrane transporter activity
TTJL18_RS09615	COG4181	ATPase activity
TTJL18_RS09620	COG0446	pyridine nucleotide-disulphide oxidoreductase
TTJL18_RS09635	COG0396	ATPase activity
TTJL18_RS09640	COG0719	Fe-S assembly protein
TTJL18_RS09645	COG0719	Fe-S assembly protein
TTJL18_RS09650	COG2146	nitrite reductase [NAD(P)H] activity
TTJL18_RS09660	COG0512	Glutamine amidotransferase of anthranilate synthase
TTJL18_RS09665	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TTJL18_RS09690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TTJL18_RS09695	COG2226	methyltransferase
TTJL18_RS09700	COG4603	Belongs to the binding-protein-dependent transport system permease family
TTJL18_RS09705	COG1079	Belongs to the binding-protein-dependent transport system permease family
TTJL18_RS09720	COG1774	PSP1 C-terminal conserved region
TTJL18_RS09725	COG0470	DNA polymerase III
TTJL18_RS09760	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TTJL18_RS09765	COG0302	gtp cyclohydrolase
TTJL18_RS09795	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TTJL18_RS09805	COG0395	ABC-type sugar transport system, permease component
TTJL18_RS09810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TTJL18_RS09815	COG1131	(ABC) transporter
TTJL18_RS09835	COG0556	nucleotide-excision repair
TTJL18_RS09840	COG0497	DNA recombination
TTJL18_RS09845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TTJL18_RS09855	COG0445	tRNA wobble uridine modification
TTJL18_RS09875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TTJL18_RS09875	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TTJL18_RS09880	COG1543	Belongs to the glycosyl hydrolase 57 family
TTJL18_RS09885	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TTJL18_RS09890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TTJL18_RS09895	COG0189	ligase activity
TTJL18_RS09910	COG0066	3-isopropylmalate dehydratase activity
TTJL18_RS09915	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TTJL18_RS09930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TTJL18_RS09935	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TTJL18_RS09940	COG1960	acyl-CoA dehydrogenase activity
TTJL18_RS09945	COG0163	prenyltransferase activity
TTJL18_RS09985	COG1668	transmembrane transport
TTJL18_RS09990	COG4555	ABC transporter
TTJL18_RS10000	COG2096	Adenosyltransferase
TTJL18_RS10015	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TTJL18_RS10020	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TTJL18_RS10035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TTJL18_RS10040	COG0723	plastoquinol--plastocyanin reductase activity
TTJL18_RS10070	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TTJL18_RS10075	COG1960	acyl-CoA dehydrogenase activity
TTJL18_RS10085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TTJL18_RS10105	COG0393	Putative heavy-metal-binding
TTJL18_RS10115	COG3956	TIGRFAM MazG family protein
TTJL18_RS10125	COG0693	protein deglycase activity
TTJL18_RS10130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TTJL18_RS10140	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TTJL18_RS10145	COG1937	Protein conserved in bacteria
TTJL18_RS10155	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TTJL18_RS10155	COG0674	pyruvate-flavodoxin oxidoreductase activity
TTJL18_RS10160	COG1013	pyruvate-flavodoxin oxidoreductase activity
TTJL18_RS10165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TTJL18_RS10175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TTJL18_RS10175	COG0072	phenylalanine-tRNA ligase activity
TTJL18_RS10185	COG0205	6-phosphofructokinase activity
TTJL18_RS10190	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TTJL18_RS10200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
TTJL18_RS10215	COG0658	competence protein
TTJL18_RS10215	COG2333	competence protein COMEC
TTJL18_RS10220	COG1475	DNA binding
TTJL18_RS10225	COG1192	Involved in chromosome partitioning
TTJL18_RS10230	COG0357	Ribosomal RNA small subunit methyltransferase G
TTJL18_RS10235	COG0445	tRNA wobble uridine modification
TTJL18_RS10350	COG0033	Phosphoglucomutase
TTJL18_RS10505	COG1845	cytochrome c oxidase, subunit III
TTJL18_RS10505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TTJL18_RS10530	COG0109	protoheme IX farnesyltransferase activity
TTJL18_RS10530	COG1612	heme a metabolic process
TTJL18_RS10670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TTJL18_RS10680	COG1404	Belongs to the peptidase S8 family
TTJL18_RS10860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TTJL18_RS10915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TTJL18_RS11095	COG1461	Dihydroxyacetone kinase
TTJL18_RS11190	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TTJL18_RS11985	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
TTJL18_RS12060	COG1845	cytochrome c oxidase, subunit III
TTJL18_RS12060	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TTJL18_RS12275	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TTJL18_RS12280	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TTJL18_RS12445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TTJL18_RS12460	COG1216	Glycosyl transferase, family 2
TTJL18_RS12480	COG0166	Belongs to the GPI family
TTJL18_RS12485	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import