locus-tag	class	description
TTMY_RS00040	COG0723	plastoquinol--plastocyanin reductase activity
TTMY_RS00045	COG0243	molybdopterin cofactor binding
TTMY_RS00055	COG3335	DDE superfamily endonuclease
TTMY_RS00070	COG3345	alpha-galactosidase
TTMY_RS00075	COG1085	galactose-1-phosphate uridylyltransferase
TTMY_RS00100	COG1304	FMN binding
TTMY_RS00150	COG1562	ergosterol biosynthetic process
TTMY_RS00160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TTMY_RS00180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TTMY_RS00190	COG1028	Short-chain dehydrogenase reductase Sdr
TTMY_RS00205	COG1028	Short-chain dehydrogenase reductase Sdr
TTMY_RS00210	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TTMY_RS00220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TTMY_RS00240	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TTMY_RS00255	COG0803	Belongs to the bacterial solute-binding protein 9 family
TTMY_RS00295	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TTMY_RS00305	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
TTMY_RS00310	COG0778	Nitroreductase
TTMY_RS00400	COG1797	cobyrinic acid a,c-diamide synthase activity
TTMY_RS00435	COG2211	Major facilitator Superfamily
TTMY_RS00470	COG1337	RAMP superfamily
TTMY_RS00505	COG1518	maintenance of DNA repeat elements
TTMY_RS00545	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TTMY_RS00575	COG1802	Transcriptional regulator
TTMY_RS00585	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TTMY_RS00640	COG2084	Dehydrogenase
TTMY_RS00660	COG1942	4-Oxalocrotonate Tautomerase
TTMY_RS00735	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TTMY_RS00740	COG0134	indole-3-glycerol-phosphate synthase activity
TTMY_RS00750	COG3311	Transcriptional regulator
TTMY_RS00755	COG1752	Esterase of the alpha-beta hydrolase superfamily
TTMY_RS00765	COG1126	abc transporter atp-binding protein
TTMY_RS00775	COG2358	TRAP transporter, solute receptor (TAXI family
TTMY_RS00780	COG2873	o-acetylhomoserine
TTMY_RS00785	COG2309	aminopeptidase activity
TTMY_RS00795	COG1796	DNA polymerase
TTMY_RS00795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TTMY_RS00800	COG1573	uracil-dna glycosylase
TTMY_RS00815	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TTMY_RS00820	COG2086	electron transfer activity
TTMY_RS00825	COG1960	acyl-CoA dehydrogenase activity
TTMY_RS00830	COG5002	protein histidine kinase activity
TTMY_RS00835	COG0745	RESPONSE REGULATOR receiver
TTMY_RS00840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TTMY_RS00855	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TTMY_RS00860	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TTMY_RS00870	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TTMY_RS00885	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TTMY_RS00890	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TTMY_RS00915	COG0010	Belongs to the arginase family
TTMY_RS00930	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TTMY_RS00935	COG0511	ligase activity, forming carbon-carbon bonds
TTMY_RS00940	COG0439	Biotin carboxylase
TTMY_RS00955	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TTMY_RS00960	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
TTMY_RS00970	COG0247	lactate metabolic process
TTMY_RS00970	COG2181	nitrate reductase activity
TTMY_RS00980	COG0861	Integral membrane protein TerC family
TTMY_RS00990	COG0039	L-malate dehydrogenase activity
TTMY_RS01005	COG0438	transferase activity, transferring glycosyl groups
TTMY_RS01065	COG3845	ABC transporter
TTMY_RS01070	COG1744	ABC transporter substrate-binding protein PnrA-like
TTMY_RS01075	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TTMY_RS01080	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TTMY_RS01085	COG0133	tryptophan synthase activity
TTMY_RS01090	COG0159	tryptophan synthase activity
TTMY_RS01095	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TTMY_RS01105	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TTMY_RS01125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TTMY_RS01130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TTMY_RS01145	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TTMY_RS01160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TTMY_RS01165	COG0768	penicillin binding
TTMY_RS01175	COG0275	rRNA processing
TTMY_RS01195	COG0254	rRNA binding
TTMY_RS01200	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TTMY_RS01225	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TTMY_RS01230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TTMY_RS01235	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TTMY_RS01240	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TTMY_RS01240	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TTMY_RS01250	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TTMY_RS01250	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TTMY_RS01260	COG2239	Acts as a magnesium transporter
TTMY_RS01265	COG1397	ADP-ribosylglycohydrolase
TTMY_RS01270	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TTMY_RS01280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TTMY_RS01305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TTMY_RS01315	COG4864	UPF0365 protein
TTMY_RS01325	COG1702	phosphate starvation-inducible protein PhoH
TTMY_RS01330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TTMY_RS01335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
TTMY_RS01355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TTMY_RS01365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TTMY_RS01395	COG0228	four-way junction DNA binding
TTMY_RS01400	COG1837	Belongs to the UPF0109 family
TTMY_RS01410	COG0336	Belongs to the RNA methyltransferase TrmD family
TTMY_RS01415	COG0335	large ribosomal subunit rRNA binding
TTMY_RS01420	COG2197	response regulator
TTMY_RS01425	COG1760	l-serine dehydratase
TTMY_RS01430	COG2897	thiosulfate sulfurtransferase activity
TTMY_RS01440	COG0582	viral genome integration into host DNA
TTMY_RS01500	COG0577	efflux transmembrane transporter activity
TTMY_RS01500	COG1136	(ABC) transporter
TTMY_RS01505	COG1136	(ABC) transporter
TTMY_RS01510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TTMY_RS01525	COG2205	protein histidine kinase activity
TTMY_RS01530	COG0745	RESPONSE REGULATOR receiver
TTMY_RS01605	COG3335	DDE superfamily endonuclease
TTMY_RS01635	COG0477	Major facilitator Superfamily
TTMY_RS01645	COG0183	Belongs to the thiolase family
TTMY_RS01650	COG1331	Highly conserved protein containing a thioredoxin domain
TTMY_RS01670	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TTMY_RS01680	COG2193	ferroxidase activity
TTMY_RS01685	COG1733	regulation of RNA biosynthetic process
TTMY_RS01690	COG1980	fructose-bisphosphate aldolase activity
TTMY_RS01705	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
TTMY_RS01750	COG2050	protein possibly involved in aromatic compounds catabolism
TTMY_RS01780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TTMY_RS01800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TTMY_RS01810	COG3769	mannosylglycerate metabolic process
TTMY_RS01825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TTMY_RS01830	COG1307	EDD domain protein, DegV family
TTMY_RS01835	COG1307	EDD domain protein, DegV family
TTMY_RS01840	COG1490	D-aminoacyl-tRNA deacylase activity
TTMY_RS01845	COG3239	Fatty acid desaturase
TTMY_RS01850	COG0149	triose-phosphate isomerase activity
TTMY_RS01910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TTMY_RS01925	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TTMY_RS01935	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TTMY_RS01940	COG0742	ribosomal rna small subunit methyltransferase
TTMY_RS01955	COG0237	dephospho-CoA kinase activity
TTMY_RS01960	COG1353	crispr-associated protein
TTMY_RS01960	COG0617	tRNA 3'-terminal CCA addition
TTMY_RS01965	COG1355	regulation of microtubule-based process
TTMY_RS01990	COG0824	Thioesterase
TTMY_RS01995	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TTMY_RS02010	COG1268	BioY protein
TTMY_RS02020	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TTMY_RS02055	COG2738	Putative neutral zinc metallopeptidase
TTMY_RS02065	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
TTMY_RS02070	COG0215	cysteine-tRNA ligase activity
TTMY_RS02075	COG1960	acyl-CoA dehydrogenase activity
TTMY_RS02080	COG0183	Belongs to the thiolase family
TTMY_RS02085	COG1024	Enoyl-CoA hydratase
TTMY_RS02085	COG1250	3-hydroxyacyl-CoA dehydrogenase
TTMY_RS02110	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
TTMY_RS02115	COG0438	transferase activity, transferring glycosyl groups
TTMY_RS02125	COG1215	transferase activity, transferring glycosyl groups
TTMY_RS02135	COG1215	transferase activity, transferring glycosyl groups
TTMY_RS02150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TTMY_RS02150	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
TTMY_RS02160	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TTMY_RS02170	COG4948	Mandelate Racemase Muconate Lactonizing
TTMY_RS02210	COG0494	nUDIX hydrolase
TTMY_RS02215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TTMY_RS02225	COG0052	Belongs to the universal ribosomal protein uS2 family
TTMY_RS02230	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TTMY_RS02235	COG0528	UMP kinase activity
TTMY_RS02240	COG0233	cytoplasmic translational termination
TTMY_RS02245	COG0575	Belongs to the CDS family
TTMY_RS02250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TTMY_RS02255	COG0750	zinc metalloprotease
TTMY_RS02260	COG0463	Glycosyl transferase, family 2
TTMY_RS02270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TTMY_RS02280	COG2359	stage V sporulation protein S
TTMY_RS02325	COG2718	Belongs to the UPF0229 family
TTMY_RS02335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TTMY_RS02340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TTMY_RS02355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TTMY_RS02365	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
TTMY_RS02370	COG1994	Peptidase M50
TTMY_RS02380	COG0617	tRNA 3'-terminal CCA addition
TTMY_RS02380	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TTMY_RS02380	COG0517	IMP dehydrogenase activity
TTMY_RS02395	COG0517	IMP dehydrogenase activity
TTMY_RS02410	COG1674	ftsk spoiiie
TTMY_RS02420	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TTMY_RS02425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
TTMY_RS02430	COG4651	solute:proton antiporter activity
TTMY_RS02430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TTMY_RS02435	COG0217	transcriptional regulatory protein
TTMY_RS02445	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TTMY_RS02475	COG5002	protein histidine kinase activity
TTMY_RS02475	COG2176	DNA-directed DNA polymerase activity
TTMY_RS02480	COG0151	Belongs to the GarS family
TTMY_RS02485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TTMY_RS02500	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TTMY_RS02520	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TTMY_RS02530	COG2353	YceI-like domain
TTMY_RS02540	COG2514	catechol 2,3-dioxygenase activity
TTMY_RS02545	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TTMY_RS02550	COG0287	Prephenate dehydrogenase
TTMY_RS02560	COG0277	FAD linked oxidase domain protein
TTMY_RS02575	COG1459	type II secretion system
TTMY_RS02585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TTMY_RS02595	COG0456	acetyltransferase
TTMY_RS02615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TTMY_RS02620	COG0730	response to heat
TTMY_RS02645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TTMY_RS02655	COG0167	dihydroorotate dehydrogenase activity
TTMY_RS02745	COG3335	DDE superfamily endonuclease
TTMY_RS02755	COG2873	o-acetylhomoserine
TTMY_RS02760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TTMY_RS02775	COG1073	alpha beta
TTMY_RS02820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TTMY_RS02845	COG0481	GTPase activity
TTMY_RS02865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TTMY_RS02915	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TTMY_RS02975	COG3842	ATPase activity
TTMY_RS02985	COG0124	histidyl-tRNA synthetase
TTMY_RS03000	COG0561	phosphatase activity
TTMY_RS03005	COG0017	Asparaginyl-tRNA synthetase
TTMY_RS03010	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
TTMY_RS03025	COG0640	Transcriptional regulator
TTMY_RS03045	COG0779	Required for maturation of 30S ribosomal subunits
TTMY_RS03060	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TTMY_RS03070	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TTMY_RS03070	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TTMY_RS03095	COG1940	carbohydrate kinase activity
TTMY_RS03105	COG1175	transmembrane transport
TTMY_RS03125	COG0477	Major facilitator Superfamily
TTMY_RS03130	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TTMY_RS03135	COG2022	thiamine diphosphate biosynthetic process
TTMY_RS03135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TTMY_RS03140	COG2022	thiamine diphosphate biosynthetic process
TTMY_RS03145	COG2104	thiamine diphosphate biosynthetic process
TTMY_RS03150	COG0352	thiamine-phosphate diphosphorylase activity
TTMY_RS03160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TTMY_RS03165	COG1587	Uroporphyrinogen-III synthase
TTMY_RS03170	COG1648	precorrin-2 dehydrogenase activity
TTMY_RS03170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TTMY_RS03175	COG0175	sulfate reduction
TTMY_RS03185	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TTMY_RS03185	COG1648	precorrin-2 dehydrogenase activity
TTMY_RS03190	COG2046	Belongs to the sulfate adenylyltransferase family
TTMY_RS03195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TTMY_RS03230	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TTMY_RS03235	COG2264	protein methyltransferase activity
TTMY_RS03270	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TTMY_RS03285	COG1215	transferase activity, transferring glycosyl groups
TTMY_RS03290	COG0297	glycogen (starch) synthase activity
TTMY_RS03290	COG0438	transferase activity, transferring glycosyl groups
TTMY_RS03295	COG0438	transferase activity, transferring glycosyl groups
TTMY_RS03305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TTMY_RS03315	COG1011	Hydrolase
TTMY_RS03320	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TTMY_RS03380	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TTMY_RS03385	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TTMY_RS03395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TTMY_RS03425	COG2189	Belongs to the N(4) N(6)-methyltransferase family
TTMY_RS03485	COG0745	RESPONSE REGULATOR receiver
TTMY_RS03500	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
TTMY_RS03545	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TTMY_RS03555	COG0740	serine-type endopeptidase activity
TTMY_RS03585	COG3870	Protein conserved in bacteria
TTMY_RS03595	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
TTMY_RS03600	COG1293	RNA-binding protein homologous to eukaryotic snRNP
TTMY_RS03605	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TTMY_RS03610	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TTMY_RS03625	COG1960	acyl-CoA dehydrogenase activity
TTMY_RS03655	COG1012	belongs to the aldehyde dehydrogenase family
TTMY_RS03655	COG2030	dehydratase
TTMY_RS03665	COG0318	PFAM AMP-dependent synthetase and ligase
TTMY_RS03670	COG1028	Short-chain dehydrogenase reductase Sdr
TTMY_RS03685	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TTMY_RS03690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
TTMY_RS03695	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
TTMY_RS03715	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TTMY_RS03720	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TTMY_RS03775	COG4475	Protein of unknown function (DUF436)
TTMY_RS03795	COG0572	uridine kinase
TTMY_RS03850	COG1063	alcohol dehydrogenase
TTMY_RS03860	COG1254	Belongs to the acylphosphatase family
TTMY_RS03865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TTMY_RS03880	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TTMY_RS03900	COG0183	Belongs to the thiolase family
TTMY_RS03905	COG0114	fumarate hydratase activity
TTMY_RS03910	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TTMY_RS03915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TTMY_RS03930	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TTMY_RS03940	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TTMY_RS03970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
TTMY_RS03985	COG0423	glycine-tRNA ligase activity
TTMY_RS03990	COG0542	response to heat
TTMY_RS03995	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TTMY_RS04045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TTMY_RS04070	COG0196	riboflavin kinase activity
TTMY_RS04080	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TTMY_RS04085	COG0509	glycine decarboxylation via glycine cleavage system
TTMY_RS04090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TTMY_RS04110	COG2151	metal-sulfur cluster biosynthetic enzyme
TTMY_RS04115	COG0861	Integral membrane protein TerC family
TTMY_RS04155	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TTMY_RS04160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TTMY_RS04170	COG0789	Transcriptional regulator
TTMY_RS04175	COG1414	Transcriptional regulator
TTMY_RS04180	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
TTMY_RS04185	COG0277	FAD linked oxidase domain protein
TTMY_RS04195	COG0247	lactate metabolic process
TTMY_RS04225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TTMY_RS04265	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TTMY_RS04275	COG0460	homoserine dehydrogenase
TTMY_RS04285	COG3744	PilT protein domain protein
TTMY_RS04290	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TTMY_RS04310	COG2226	methyltransferase
TTMY_RS04315	COG2226	methyltransferase
TTMY_RS04320	COG0366	Alpha amylase catalytic
TTMY_RS04330	COG0037	tRNA processing
TTMY_RS04335	COG2104	thiamine diphosphate biosynthetic process
TTMY_RS04345	COG0517	IMP dehydrogenase activity
TTMY_RS04360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TTMY_RS04365	COG0601	transmembrane transport
TTMY_RS04370	COG0747	negative chemotaxis
TTMY_RS04375	COG0604	alcohol dehydrogenase
TTMY_RS04375	COG1028	Short-chain dehydrogenase reductase Sdr
TTMY_RS04375	COG3321	synthase
TTMY_RS04380	COG0492	ferredoxin-NADP+ reductase activity
TTMY_RS04410	COG1028	Short-chain dehydrogenase reductase Sdr
TTMY_RS04420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TTMY_RS04420	COG1213	nucleotidyl transferase
TTMY_RS04425	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TTMY_RS04430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TTMY_RS04435	COG1104	cysteine desulfurase activity
TTMY_RS04440	COG1959	2 iron, 2 sulfur cluster binding
TTMY_RS04450	COG1121	(ABC) transporter
TTMY_RS04480	COG1022	Amp-dependent synthetase and ligase
TTMY_RS04500	COG0230	Belongs to the bacterial ribosomal protein bL34 family
TTMY_RS04505	COG0594	ribonuclease P activity
TTMY_RS04510	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TTMY_RS04515	COG0706	membrane insertase activity
TTMY_RS04540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TTMY_RS04555	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
TTMY_RS04570	COG0516	GMP reductase activity
TTMY_RS04570	COG0517	IMP dehydrogenase activity
TTMY_RS04575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TTMY_RS04580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TTMY_RS04585	COG0131	Imidazoleglycerol-phosphate dehydratase
TTMY_RS04590	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TTMY_RS04595	COG0778	Nitroreductase
TTMY_RS04630	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TTMY_RS04635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TTMY_RS04640	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TTMY_RS04650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TTMY_RS04655	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TTMY_RS04660	COG0232	Belongs to the dGTPase family. Type 2 subfamily
TTMY_RS04665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TTMY_RS04680	COG0564	pseudouridine synthase activity
TTMY_RS04685	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TTMY_RS04690	COG2255	four-way junction helicase activity
TTMY_RS04720	COG1063	alcohol dehydrogenase
TTMY_RS04775	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TTMY_RS04775	COG1605	Chorismate mutase
TTMY_RS04780	COG0805	protein transport
TTMY_RS04785	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TTMY_RS04795	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TTMY_RS04830	COG1175	transmembrane transport
TTMY_RS04855	COG0492	ferredoxin-NADP+ reductase activity
TTMY_RS04865	COG0792	nuclease activity
TTMY_RS04900	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TTMY_RS04940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TTMY_RS04965	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TTMY_RS04980	COG0297	glycogen (starch) synthase activity
TTMY_RS04985	COG2105	PFAM AIG2 family protein
TTMY_RS05000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TTMY_RS05005	COG1067	ATP-dependent peptidase activity
TTMY_RS05015	COG2199	diguanylate cyclase activity
TTMY_RS05040	COG0667	Aldo Keto reductase
TTMY_RS05075	COG0277	FAD linked oxidase domain protein
TTMY_RS05085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TTMY_RS05095	COG0569	domain protein
TTMY_RS05095	COG0475	glutathione-regulated potassium exporter activity
TTMY_RS05105	COG0436	Aminotransferase
TTMY_RS05120	COG1597	lipid kinase activity
TTMY_RS05135	COG0123	including yeast histone deacetylase and acetoin utilization protein
TTMY_RS05145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
TTMY_RS05155	COG0004	ammonium transporteR
TTMY_RS05160	COG0347	Belongs to the P(II) protein family
TTMY_RS05165	COG1420	regulation of RNA biosynthetic process
TTMY_RS05170	COG0314	molybdopterin synthase activity
TTMY_RS05185	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TTMY_RS05195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TTMY_RS05230	COG1126	abc transporter atp-binding protein
TTMY_RS05235	COG2720	vancomycin resistance protein
TTMY_RS05255	COG0135	phosphoribosylanthranilate isomerase activity
TTMY_RS05285	COG4712	double-strand break repair protein
TTMY_RS05295	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TTMY_RS05300	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTMY_RS05305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTMY_RS05310	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTMY_RS05320	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
TTMY_RS05325	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TTMY_RS05330	COG1034	ATP synthesis coupled electron transport
TTMY_RS05335	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TTMY_RS05340	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTMY_RS05345	COG0839	Belongs to the complex I subunit 6 family
TTMY_RS05350	COG0713	ATP synthesis coupled electron transport
TTMY_RS05360	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TTMY_RS05365	COG1007	ATP synthesis coupled electron transport
TTMY_RS05370	COG0018	arginyl-trna synthetase
TTMY_RS05375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TTMY_RS05380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TTMY_RS05395	COG2070	2-Nitropropane dioxygenase
TTMY_RS05410	COG0745	RESPONSE REGULATOR receiver
TTMY_RS05435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TTMY_RS05445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
TTMY_RS05455	COG0582	viral genome integration into host DNA
TTMY_RS05510	COG4983	Phage plasmid primase, P4 family domain protein
TTMY_RS05550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TTMY_RS05575	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TTMY_RS05585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TTMY_RS05600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TTMY_RS05610	COG3546	catalase activity
TTMY_RS05615	COG0583	DNA-binding transcription factor activity
TTMY_RS05635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TTMY_RS05640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TTMY_RS05655	COG0717	Belongs to the dCTP deaminase family
TTMY_RS05670	COG1028	Short-chain dehydrogenase reductase Sdr
TTMY_RS05675	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TTMY_RS05700	COG0515	serine threonine protein kinase
TTMY_RS05700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TTMY_RS05725	COG0704	Plays a role in the regulation of phosphate uptake
TTMY_RS05730	COG4191	Histidine kinase
TTMY_RS05735	COG0745	RESPONSE REGULATOR receiver
TTMY_RS05740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TTMY_RS05745	COG1187	pseudouridine synthase activity
TTMY_RS05785	COG1902	pentaerythritol trinitrate reductase activity
TTMY_RS05805	COG0495	leucyl-tRNA aminoacylation
TTMY_RS05810	COG0539	negative regulation of cytoplasmic translation
TTMY_RS05825	COG0442	prolyl-tRNA aminoacylation
TTMY_RS05905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
TTMY_RS05920	COG0432	Pfam Uncharacterised protein family UPF0047
TTMY_RS05925	COG3253	May function as heme-dependent peroxidase
TTMY_RS05930	COG0668	transmembrane transport
TTMY_RS05940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TTMY_RS05945	COG2217	Heavy metal translocating P-type atpase
TTMY_RS05970	COG5002	protein histidine kinase activity
TTMY_RS06025	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TTMY_RS06030	COG0822	iron-sulfur transferase activity
TTMY_RS06050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TTMY_RS06070	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TTMY_RS06075	COG0284	orotidine-5'-phosphate decarboxylase activity
TTMY_RS06095	COG0416	fatty acid biosynthetic process
TTMY_RS06100	COG3118	belongs to the thioredoxin family
TTMY_RS06120	COG0438	transferase activity, transferring glycosyl groups
TTMY_RS06140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TTMY_RS06155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TTMY_RS06210	COG0825	malonyl-CoA metabolic process
TTMY_RS06280	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TTMY_RS06285	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TTMY_RS06290	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TTMY_RS06390	COG0315	cyclic pyranopterin monophosphate synthase activity
TTMY_RS06395	COG2860	membrane
TTMY_RS06400	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TTMY_RS06415	COG1694	Mazg nucleotide pyrophosphohydrolase
TTMY_RS06420	COG1803	Methylglyoxal synthase
TTMY_RS06435	COG0154	amidase activity
TTMY_RS06440	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TTMY_RS06465	COG2154	pterin-4-alpha-carbinolamine dehydratase
TTMY_RS06470	COG1607	acyl-coa hydrolase
TTMY_RS06480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TTMY_RS06490	COG1840	ABC-type Fe3 transport system, periplasmic component
TTMY_RS06505	COG0235	Class ii aldolase
TTMY_RS06510	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TTMY_RS06515	COG0085	RNA polymerase activity
TTMY_RS06525	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TTMY_RS06530	COG1077	Cell shape determining protein MreB Mrl
TTMY_RS06535	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TTMY_RS06535	COG1418	mRNA catabolic process
TTMY_RS06540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TTMY_RS06550	COG1058	Belongs to the CinA family
TTMY_RS06550	COG1546	Belongs to the CinA family
TTMY_RS06555	COG0354	folic acid binding
TTMY_RS06570	COG4948	Mandelate Racemase Muconate Lactonizing
TTMY_RS06585	COG1175	transmembrane transport
TTMY_RS06595	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
TTMY_RS06605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TTMY_RS06620	COG4181	ATPase activity
TTMY_RS06625	COG0446	pyridine nucleotide-disulphide oxidoreductase
TTMY_RS06640	COG0396	ATPase activity
TTMY_RS06645	COG0719	Fe-S assembly protein
TTMY_RS06650	COG0719	Fe-S assembly protein
TTMY_RS06655	COG2146	nitrite reductase [NAD(P)H] activity
TTMY_RS06690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TTMY_RS06695	COG2226	methyltransferase
TTMY_RS06705	COG1079	Belongs to the binding-protein-dependent transport system permease family
TTMY_RS06725	COG0470	DNA polymerase III
TTMY_RS06775	COG0302	gtp cyclohydrolase
TTMY_RS06800	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TTMY_RS06810	COG0395	ABC-type sugar transport system, permease component
TTMY_RS06825	COG1131	(ABC) transporter
TTMY_RS06845	COG0556	nucleotide-excision repair
TTMY_RS06850	COG0497	DNA recombination
TTMY_RS06855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TTMY_RS06865	COG0445	tRNA wobble uridine modification
TTMY_RS06890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TTMY_RS06890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TTMY_RS06900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TTMY_RS06905	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TTMY_RS06915	COG0189	ligase activity
TTMY_RS06930	COG0066	3-isopropylmalate dehydratase activity
TTMY_RS06935	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TTMY_RS06950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TTMY_RS06955	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TTMY_RS06960	COG1960	acyl-CoA dehydrogenase activity
TTMY_RS06965	COG0163	prenyltransferase activity
TTMY_RS07010	COG4555	ABC transporter
TTMY_RS07035	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TTMY_RS07040	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TTMY_RS07055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TTMY_RS07060	COG0723	plastoquinol--plastocyanin reductase activity
TTMY_RS07085	COG1653	transport
TTMY_RS07090	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TTMY_RS07095	COG1960	acyl-CoA dehydrogenase activity
TTMY_RS07105	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TTMY_RS07130	COG0393	Putative heavy-metal-binding
TTMY_RS07140	COG3956	TIGRFAM MazG family protein
TTMY_RS07165	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TTMY_RS07170	COG1937	Protein conserved in bacteria
TTMY_RS07180	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TTMY_RS07180	COG0674	pyruvate-flavodoxin oxidoreductase activity
TTMY_RS07185	COG1013	pyruvate-flavodoxin oxidoreductase activity
TTMY_RS07210	COG0205	6-phosphofructokinase activity
TTMY_RS07215	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TTMY_RS07225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
TTMY_RS07240	COG2333	competence protein COMEC
TTMY_RS07240	COG0658	competence protein
TTMY_RS07245	COG1475	DNA binding
TTMY_RS07250	COG1192	Involved in chromosome partitioning
TTMY_RS07255	COG0357	Ribosomal RNA small subunit methyltransferase G
TTMY_RS07265	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TTMY_RS07275	COG0148	phosphopyruvate hydratase activity
TTMY_RS07280	COG0469	pyruvate kinase activity
TTMY_RS07295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TTMY_RS07305	COG1842	Phage shock protein A
TTMY_RS07340	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TTMY_RS07345	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TTMY_RS07355	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
TTMY_RS07360	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
TTMY_RS07365	COG1496	oxidoreductase activity
TTMY_RS07370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TTMY_RS07375	COG1278	Cold shock
TTMY_RS07385	COG1653	transport
TTMY_RS07400	COG0033	Phosphoglucomutase
TTMY_RS07415	COG2814	Major facilitator Superfamily
TTMY_RS07435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TTMY_RS07445	COG0181	hydroxymethylbilane synthase activity
TTMY_RS07455	COG0285	dihydrofolate synthase activity
TTMY_RS07460	COG0436	Aminotransferase
TTMY_RS07465	COG0521	Mo-molybdopterin cofactor biosynthetic process
TTMY_RS07490	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TTMY_RS07495	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TTMY_RS07500	COG1993	acr, cog1993
TTMY_RS07505	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TTMY_RS07515	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TTMY_RS07525	COG1335	isochorismatase
TTMY_RS07530	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TTMY_RS07545	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
TTMY_RS07550	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
TTMY_RS07575	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TTMY_RS07620	COG3335	DDE superfamily endonuclease
TTMY_RS07690	COG2226	methyltransferase
TTMY_RS07715	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
TTMY_RS07720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TTMY_RS07725	COG0022	dehydrogenase e1 component
TTMY_RS07730	COG1598	PFAM Uncharacterised protein family UPF0150
TTMY_RS07745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TTMY_RS07790	COG3335	DDE superfamily endonuclease
TTMY_RS07810	COG0321	lipoyl(octanoyl) transferase activity
TTMY_RS07815	COG0300	oxidoreductase activity
TTMY_RS07830	COG0359	binds to the 23S rRNA
TTMY_RS07835	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TTMY_RS07840	COG0629	single-stranded DNA binding
TTMY_RS07855	COG0081	regulation of translation
TTMY_RS07865	COG0250	Participates in transcription elongation, termination and antitermination
TTMY_RS07870	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TTMY_RS07875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TTMY_RS07905	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TTMY_RS07920	COG0735	belongs to the Fur family
TTMY_RS07940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TTMY_RS07945	COG0573	inorganic phosphate transmembrane transporter activity
TTMY_RS07950	COG0581	inorganic phosphate transmembrane transporter activity
TTMY_RS07955	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TTMY_RS07965	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TTMY_RS08005	COG0459	protein refolding
TTMY_RS08010	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TTMY_RS08015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TTMY_RS08030	COG0166	Belongs to the GPI family
TTMY_RS08035	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
TTMY_RS08045	COG0505	Belongs to the CarA family
TTMY_RS08055	COG0165	Argininosuccinate lyase
TTMY_RS08060	COG0137	argininosuccinate synthase activity
TTMY_RS08080	COG1024	Enoyl-CoA hydratase
TTMY_RS08085	COG0632	four-way junction helicase activity
TTMY_RS08090	COG1011	Hydrolase
TTMY_RS08100	COG1611	Belongs to the LOG family
TTMY_RS08105	COG0589	response to stress
TTMY_RS08110	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TTMY_RS08190	COG2010	Cytochrome c
TTMY_RS08190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TTMY_RS08220	COG0582	viral genome integration into host DNA
TTMY_RS08225	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TTMY_RS08240	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
TTMY_RS08245	COG1187	pseudouridine synthase activity
TTMY_RS08250	COG1024	Enoyl-CoA hydratase
TTMY_RS08255	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TTMY_RS08260	COG0686	Belongs to the AlaDH PNT family
TTMY_RS08270	COG1461	Dihydroxyacetone kinase
TTMY_RS08285	COG4591	ABC-type transport system involved in lipoprotein release permease component
TTMY_RS08290	COG0222	ribosome binding
TTMY_RS08295	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TTMY_RS08305	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
TTMY_RS08340	COG2272	Belongs to the type-B carboxylesterase lipase family
TTMY_RS08345	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TTMY_RS08355	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TTMY_RS08370	COG0477	Major facilitator Superfamily
TTMY_RS08385	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TTMY_RS08395	COG0105	UTP biosynthetic process
TTMY_RS08405	COG0583	DNA-binding transcription factor activity
TTMY_RS08415	COG0508	dehydrogenase complex catalyzes the overall conversion of
TTMY_RS08445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TTMY_RS08455	COG1278	Cold shock
TTMY_RS08465	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TTMY_RS08470	COG1968	undecaprenyl-diphosphatase activity
TTMY_RS08475	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TTMY_RS08480	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TTMY_RS08495	COG1309	transcriptional regulator
TTMY_RS08500	COG4242	Belongs to the peptidase S51 family
TTMY_RS08515	COG0802	atpase or kinase
TTMY_RS08530	COG0049	tRNA binding
TTMY_RS08545	COG0051	transcription antitermination factor activity, RNA binding
TTMY_RS08555	COG0088	Forms part of the polypeptide exit tunnel
TTMY_RS08560	COG0089	rRNA binding
TTMY_RS08565	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TTMY_RS08570	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TTMY_RS08580	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TTMY_RS08585	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TTMY_RS08590	COG0255	Belongs to the universal ribosomal protein uL29 family
TTMY_RS08600	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TTMY_RS08615	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TTMY_RS08620	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TTMY_RS08625	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TTMY_RS08650	COG0201	protein transport
TTMY_RS08655	COG0563	adenylate kinase activity
TTMY_RS08665	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TTMY_RS08675	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TTMY_RS08680	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TTMY_RS08685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TTMY_RS08690	COG0202	RNA polymerase activity
TTMY_RS08695	COG0203	ribosomal protein L17
TTMY_RS08725	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TTMY_RS08745	COG0142	geranyltranstransferase activity
TTMY_RS08750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TTMY_RS08785	COG0366	Alpha amylase catalytic
TTMY_RS08795	COG1193	negative regulation of DNA recombination
TTMY_RS08800	COG1611	Belongs to the LOG family
TTMY_RS08805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TTMY_RS08810	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TTMY_RS08835	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TTMY_RS08840	COG0006	proline dipeptidase activity
TTMY_RS08845	COG0316	Belongs to the HesB IscA family
TTMY_RS08855	COG0601	transmembrane transport
TTMY_RS08860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TTMY_RS08865	COG0101	tRNA pseudouridine synthase activity
TTMY_RS08870	COG3842	ATPase activity
TTMY_RS08880	COG1840	ABC-type Fe3 transport system, periplasmic component
TTMY_RS08905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TTMY_RS08910	COG2897	thiosulfate sulfurtransferase activity
TTMY_RS08925	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TTMY_RS08930	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TTMY_RS08935	COG0537	adenosine 5'-monophosphoramidase activity
TTMY_RS08960	COG1011	Hydrolase
TTMY_RS08965	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TTMY_RS08990	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TTMY_RS08995	COG4946	Tricorn protease homolog
TTMY_RS08995	COG1506	peptidase
TTMY_RS08995	COG0823	Involved in the tonB-independent uptake of proteins
TTMY_RS09020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TTMY_RS09025	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TTMY_RS09030	COG0113	porphobilinogen synthase activity
TTMY_RS09045	COG0631	protein serine/threonine phosphatase activity
TTMY_RS09075	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TTMY_RS09080	COG0193	aminoacyl-tRNA hydrolase activity
TTMY_RS09085	COG1181	Belongs to the D-alanine--D-alanine ligase family
TTMY_RS09090	COG0187	DNA topoisomerase II activity
TTMY_RS09105	COG0827	DNA restriction-modification system
TTMY_RS09105	COG0732	type I restriction modification DNA specificity domain
TTMY_RS09110	COG0156	8-amino-7-oxononanoate synthase activity
TTMY_RS09130	COG0506	proline dehydrogenase activity
TTMY_RS09135	COG1012	belongs to the aldehyde dehydrogenase family
TTMY_RS09140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TTMY_RS09145	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TTMY_RS09185	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
TTMY_RS09200	COG2385	sporulation resulting in formation of a cellular spore
TTMY_RS09205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TTMY_RS09215	COG0194	GDP metabolic process
TTMY_RS09220	COG1758	RNA polymerase activity
TTMY_RS09225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TTMY_RS09230	COG1438	arginine binding
TTMY_RS09235	COG2095	MarC family integral membrane protein
TTMY_RS09245	COG0328	RNA-DNA hybrid ribonuclease activity
TTMY_RS09265	COG4274	PFAM GYD family protein
TTMY_RS09270	COG4636	protein conserved in cyanobacteria
TTMY_RS09285	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TTMY_RS09290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TTMY_RS09305	COG2050	protein possibly involved in aromatic compounds catabolism
TTMY_RS09330	COG0037	tRNA processing
TTMY_RS09330	COG0590	tRNA wobble adenosine to inosine editing
TTMY_RS09345	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TTMY_RS09350	COG0538	isocitrate dehydrogenase activity
TTMY_RS09355	COG0557	exoribonuclease II activity
TTMY_RS09370	COG0585	pseudouridine synthase activity
TTMY_RS09400	COG0497	DNA recombination
TTMY_RS09440	COG0047	phosphoribosylformylglycinamidine synthase activity
TTMY_RS09465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TTMY_RS09500	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TTMY_RS09515	COG5002	protein histidine kinase activity
TTMY_RS09515	COG3850	Histidine kinase
TTMY_RS09525	COG1272	protein, Hemolysin III
TTMY_RS09530	COG0574	Belongs to the PEP-utilizing enzyme family
TTMY_RS09530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TTMY_RS09535	COG0714	Associated with various cellular activities
TTMY_RS09545	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
TTMY_RS09560	COG0616	signal peptide processing
TTMY_RS09565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TTMY_RS09570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TTMY_RS09575	COG0443	Heat shock 70 kDa protein
TTMY_RS09580	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TTMY_RS09585	COG0484	heat shock protein binding
TTMY_RS09590	COG0789	Transcriptional regulator
TTMY_RS09595	COG0542	response to heat
TTMY_RS09620	COG3118	belongs to the thioredoxin family
TTMY_RS09640	COG0490	domain, Protein
TTMY_RS09645	COG0475	glutathione-regulated potassium exporter activity
TTMY_RS09660	COG0517	IMP dehydrogenase activity
TTMY_RS09660	COG0617	tRNA 3'-terminal CCA addition
TTMY_RS09660	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TTMY_RS09665	COG0475	glutathione-regulated potassium exporter activity
TTMY_RS09675	COG0305	Participates in initiation and elongation during chromosome replication
TTMY_RS09680	COG0840	transmembrane signaling receptor activity
TTMY_RS09735	COG0504	CTP synthase activity
TTMY_RS09740	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TTMY_RS09745	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TTMY_RS09780	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TTMY_RS09785	COG2009	succinate dehydrogenase
TTMY_RS09800	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TTMY_RS09805	COG0017	Asparaginyl-tRNA synthetase
TTMY_RS09820	COG0084	hydrolase, TatD family'
TTMY_RS09825	COG0427	acetyl-CoA hydrolase
TTMY_RS09830	COG0686	Belongs to the AlaDH PNT family
TTMY_RS09835	COG1494	fructose-1,6-bisphosphatase
TTMY_RS09840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TTMY_RS09840	COG0140	phosphoribosyl-ATP diphosphatase activity
TTMY_RS09845	COG0107	imidazoleglycerol-phosphate synthase activity
TTMY_RS09855	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
TTMY_RS09865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TTMY_RS09875	COG2045	Belongs to the ComB family
TTMY_RS09880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TTMY_RS09885	COG1136	(ABC) transporter
TTMY_RS09895	COG1024	Enoyl-CoA hydratase
TTMY_RS09910	COG3360	Dodecin
TTMY_RS09915	COG0318	PFAM AMP-dependent synthetase and ligase
TTMY_RS09945	COG3842	ATPase activity
TTMY_RS09950	COG2010	Cytochrome c
TTMY_RS09970	COG3258	Cytochrome c
TTMY_RS09975	COG2010	Cytochrome c
TTMY_RS09985	COG2010	Cytochrome c
TTMY_RS09990	COG3258	Cytochrome c
TTMY_RS10015	COG3258	Cytochrome c
TTMY_RS10020	COG0785	Cytochrome C biogenesis protein
TTMY_RS10025	COG4133	protoheme IX ABC transporter activity
TTMY_RS10035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TTMY_RS10045	COG1138	Cytochrome C-type biogenesis protein
TTMY_RS10050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TTMY_RS10055	COG4235	cytochrome complex assembly
TTMY_RS10055	COG3088	subunit of a heme lyase
TTMY_RS10080	COG5343	regulation of RNA biosynthetic process
TTMY_RS10125	COG0268	Binds directly to 16S ribosomal RNA
TTMY_RS10140	COG0083	homoserine kinase activity
TTMY_RS10150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TTMY_RS10155	COG1160	GTP binding
TTMY_RS10165	COG0736	holo-[acyl-carrier-protein] synthase activity
TTMY_RS10170	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
TTMY_RS10170	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TTMY_RS10175	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TTMY_RS10180	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TTMY_RS10185	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TTMY_RS10190	COG1450	Type ii and iii secretion system protein
TTMY_RS10215	COG0473	3-isopropylmalate dehydrogenase activity
TTMY_RS10250	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
TTMY_RS10260	COG0860	N-Acetylmuramoyl-L-alanine amidase
TTMY_RS10270	COG0515	serine threonine protein kinase
TTMY_RS10270	COG2815	serine threonine protein kinase
TTMY_RS10285	COG1556	Lactate utilization protein
TTMY_RS10290	COG1139	Iron-sulfur cluster binding protein
TTMY_RS10325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TTMY_RS10340	COG1324	tolerance protein
TTMY_RS10350	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TTMY_RS10365	COG2197	response regulator
TTMY_RS10380	COG0776	regulation of translation
TTMY_RS10390	COG1515	deoxyribonuclease V activity
TTMY_RS10400	COG1482	cell wall glycoprotein biosynthetic process
TTMY_RS10405	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TTMY_RS10410	COG0372	Belongs to the citrate synthase family
TTMY_RS10415	COG1132	(ABC) transporter
TTMY_RS10420	COG1132	(ABC) transporter
TTMY_RS10425	COG0285	dihydrofolate synthase activity
TTMY_RS10455	COG0559	Belongs to the binding-protein-dependent transport system permease family
TTMY_RS10465	COG0174	glutamine synthetase
TTMY_RS10470	COG0737	Belongs to the 5'-nucleotidase family
TTMY_RS10480	COG2010	Cytochrome c
TTMY_RS10500	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TTMY_RS10505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
TTMY_RS10510	COG0788	formyltetrahydrofolate deformylase activity
TTMY_RS10515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TTMY_RS10530	COG2358	TRAP transporter, solute receptor (TAXI family
TTMY_RS10545	COG0517	IMP dehydrogenase activity
TTMY_RS10545	COG1994	Peptidase M50
TTMY_RS10555	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TTMY_RS10585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TTMY_RS10600	COG0746	molybdenum cofactor guanylyltransferase activity
TTMY_RS10610	COG4603	Belongs to the binding-protein-dependent transport system permease family
TTMY_RS10615	COG1079	Belongs to the binding-protein-dependent transport system permease family
TTMY_RS10625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TTMY_RS10630	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TTMY_RS10635	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TTMY_RS10635	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TTMY_RS10645	COG0793	Belongs to the peptidase S41A family
TTMY_RS10650	COG2884	Cell division ATP-binding protein ftsE
TTMY_RS10655	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
TTMY_RS10675	COG0420	3'-5' exonuclease activity
TTMY_RS10680	COG0419	ATPase involved in DNA repair
TTMY_RS10700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TTMY_RS10710	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TTMY_RS10735	COG1269	ATP hydrolysis coupled proton transport
TTMY_RS10745	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
TTMY_RS10755	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
TTMY_RS10765	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TTMY_RS10770	COG1394	ATPase activity, coupled to movement of substances
TTMY_RS10790	COG0612	Peptidase, M16
TTMY_RS10795	COG0612	Peptidase, M16
TTMY_RS10805	COG1250	3-hydroxyacyl-CoA dehydrogenase
TTMY_RS10830	COG1205	dead DEAH box helicase
TTMY_RS10830	COG1111	helicase
TTMY_RS10835	COG0393	Putative heavy-metal-binding
TTMY_RS10855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TTMY_RS10860	COG0653	protein targeting
TTMY_RS10865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TTMY_RS10900	COG2894	cell division
TTMY_RS10905	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
TTMY_RS10915	COG3842	ATPase activity
TTMY_RS10925	COG1177	transmembrane transport
TTMY_RS10940	COG0129	dihydroxy-acid dehydratase activity
TTMY_RS10960	COG0473	3-isopropylmalate dehydrogenase activity
TTMY_RS10965	COG0066	3-isopropylmalate dehydratase activity
TTMY_RS10970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TTMY_RS10975	COG0544	peptidyl-prolyl cis-trans isomerase activity
TTMY_RS10980	COG0180	Tryptophanyl-tRNA synthetase
TTMY_RS10995	COG4636	protein conserved in cyanobacteria
TTMY_RS11010	COG2165	general secretion pathway protein
TTMY_RS11045	COG0492	ferredoxin-NADP+ reductase activity
TTMY_RS11050	COG0028	Belongs to the TPP enzyme family
TTMY_RS11055	COG0440	acetolactate synthase activity
TTMY_RS11060	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TTMY_RS11070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TTMY_RS11085	COG1131	(ABC) transporter
TTMY_RS11105	COG2165	general secretion pathway protein
TTMY_RS11115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TTMY_RS11130	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TTMY_RS11140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TTMY_RS11145	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TTMY_RS11170	COG2322	membrane
TTMY_RS11210	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TTMY_RS11215	COG0012	GTP binding
TTMY_RS11230	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
TTMY_RS11235	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
TTMY_RS11260	COG2313	pseudouridylate synthase activity
TTMY_RS11265	COG1426	Protein conserved in bacteria
TTMY_RS11270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TTMY_RS11275	COG0569	domain protein
TTMY_RS11290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TTMY_RS11295	COG0765	amino acid transport
TTMY_RS11325	COG4607	ABC-type enterochelin transport system periplasmic component
TTMY_RS11340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TTMY_RS11345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TTMY_RS11355	COG2329	Antibiotic biosynthesis monooxygenase
TTMY_RS11360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TTMY_RS11370	COG1607	acyl-coa hydrolase
TTMY_RS11410	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TTMY_RS11420	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
TTMY_RS11420	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TTMY_RS11485	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TTMY_RS11500	COG1337	RAMP superfamily
TTMY_RS11520	COG2391	methyltransferase activity
TTMY_RS11530	COG2226	methyltransferase
TTMY_RS11540	COG1233	COG1233 Phytoene dehydrogenase and related
TTMY_RS11570	COG2414	aldehyde ferredoxin oxidoreductase
TTMY_RS11610	COG2205	protein histidine kinase activity
TTMY_RS11695	COG1192	Involved in chromosome partitioning
TTMY_RS11720	COG4974	Belongs to the 'phage' integrase family