locus-tag	class	description
TVNIR_RS00010	COG1132	(ABC) transporter
TVNIR_RS00015	COG0438	transferase activity, transferring glycosyl groups
TVNIR_RS00020	COG0438	transferase activity, transferring glycosyl groups
TVNIR_RS00060	COG1598	PFAM Uncharacterised protein family UPF0150
TVNIR_RS00095	COG1484	DNA-dependent DNA replication
TVNIR_RS00235	COG0463	Glycosyl transferase, family 2
TVNIR_RS00245	COG4969	Belongs to the N-Me-Phe pilin family
TVNIR_RS00255	COG4636	protein conserved in cyanobacteria
TVNIR_RS00265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TVNIR_RS00265	COG2111	Na H antiporter
TVNIR_RS00285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TVNIR_RS00290	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
TVNIR_RS00290	COG0662	Cupin 2, conserved barrel domain protein
TVNIR_RS00310	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TVNIR_RS00315	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TVNIR_RS00320	COG0140	phosphoribosyl-ATP diphosphatase activity
TVNIR_RS00325	COG0107	imidazoleglycerol-phosphate synthase activity
TVNIR_RS00330	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TVNIR_RS00335	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TVNIR_RS00340	COG0131	Imidazoleglycerol-phosphate dehydratase
TVNIR_RS00370	COG4106	trans-aconitate 2-methyltransferase activity
TVNIR_RS00375	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
TVNIR_RS00390	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TVNIR_RS00395	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TVNIR_RS00405	COG2226	methyltransferase
TVNIR_RS00415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
TVNIR_RS00425	COG2111	Na H antiporter
TVNIR_RS00425	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TVNIR_RS00430	COG0651	ATP synthesis coupled electron transport
TVNIR_RS00435	COG0651	ATP synthesis coupled electron transport
TVNIR_RS00440	COG1006	Multisubunit Na H antiporter MnhC subunit
TVNIR_RS00445	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TVNIR_RS00445	COG2111	Na H antiporter
TVNIR_RS00455	COG1320	monovalent cation:proton antiporter activity
TVNIR_RS00475	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TVNIR_RS00490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TVNIR_RS00495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TVNIR_RS00500	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
TVNIR_RS00520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TVNIR_RS00525	COG2197	response regulator
TVNIR_RS00575	COG3267	Type II secretory pathway component ExeA
TVNIR_RS00575	COG3409	Peptidoglycan-binding domain 1 protein
TVNIR_RS00605	COG3706	GGDEF domain
TVNIR_RS00615	COG2010	Cytochrome c
TVNIR_RS00625	COG1404	Belongs to the peptidase S8 family
TVNIR_RS00640	COG1074	ATP-dependent DNA helicase activity
TVNIR_RS00645	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TVNIR_RS00655	COG2226	methyltransferase
TVNIR_RS00670	COG0247	lactate metabolic process
TVNIR_RS00675	COG1139	Iron-sulfur cluster binding protein
TVNIR_RS00680	COG1620	l-lactate permease
TVNIR_RS00685	COG2226	methyltransferase
TVNIR_RS00695	COG1595	DNA-templated transcription, initiation
TVNIR_RS00715	COG1111	helicase
TVNIR_RS00715	COG1205	dead DEAH box helicase
TVNIR_RS00750	COG0142	geranyltranstransferase activity
TVNIR_RS00755	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TVNIR_RS00760	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TVNIR_RS00765	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TVNIR_RS00770	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TVNIR_RS00775	COG0268	Binds directly to 16S ribosomal RNA
TVNIR_RS00790	COG0196	riboflavin kinase activity
TVNIR_RS00795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TVNIR_RS00800	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TVNIR_RS00805	COG1047	Peptidyl-prolyl cis-trans
TVNIR_RS00810	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TVNIR_RS00870	COG0606	chelatase, subunit chli
TVNIR_RS00880	COG1028	Short-chain dehydrogenase reductase Sdr
TVNIR_RS00895	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TVNIR_RS00900	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TVNIR_RS00910	COG2226	methyltransferase
TVNIR_RS00915	COG3278	Belongs to the heme-copper respiratory oxidase family
TVNIR_RS00930	COG2010	Cytochrome c
TVNIR_RS00935	COG0348	domain, Protein
TVNIR_RS00945	COG2217	Heavy metal translocating P-type atpase
TVNIR_RS00980	COG2884	Cell division ATP-binding protein ftsE
TVNIR_RS00985	COG0552	protein localization to endoplasmic reticulum
TVNIR_RS00990	COG0612	Peptidase, M16
TVNIR_RS00995	COG0612	Peptidase, M16
TVNIR_RS01000	COG0742	ribosomal rna small subunit methyltransferase
TVNIR_RS01015	COG2197	response regulator
TVNIR_RS01035	COG3001	Fructosamine kinase
TVNIR_RS01040	COG0741	lytic transglycosylase activity
TVNIR_RS01045	COG1187	pseudouridine synthase activity
TVNIR_RS01060	COG0039	L-malate dehydrogenase activity
TVNIR_RS01065	COG0281	malic enzyme
TVNIR_RS01075	COG0254	rRNA binding
TVNIR_RS01080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TVNIR_RS01095	COG0058	SHG alpha-glucan phosphorylase activity
TVNIR_RS01120	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TVNIR_RS01125	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
TVNIR_RS01145	COG3153	acetyltransferase
TVNIR_RS01145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TVNIR_RS01185	COG0483	inositol monophosphate 1-phosphatase activity
TVNIR_RS01205	COG0488	(ABC) transporter
TVNIR_RS01210	COG0446	pyridine nucleotide-disulphide oxidoreductase
TVNIR_RS01220	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
TVNIR_RS01225	COG1138	Cytochrome C-type biogenesis protein
TVNIR_RS01230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TVNIR_RS01235	COG3088	subunit of a heme lyase
TVNIR_RS01255	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
TVNIR_RS01265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TVNIR_RS01275	COG3850	Histidine kinase
TVNIR_RS01280	COG2197	response regulator
TVNIR_RS01290	COG2918	glutathione biosynthetic process
TVNIR_RS01300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TVNIR_RS01305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TVNIR_RS01310	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TVNIR_RS01315	COG0438	transferase activity, transferring glycosyl groups
TVNIR_RS01350	COG0494	nUDIX hydrolase
TVNIR_RS01360	COG1011	Hydrolase
TVNIR_RS01415	COG0540	Belongs to the ATCase OTCase family
TVNIR_RS01430	COG1678	Uncharacterized ACR, COG1678
TVNIR_RS01435	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
TVNIR_RS01455	COG0189	ligase activity
TVNIR_RS01495	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TVNIR_RS01500	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TVNIR_RS01500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TVNIR_RS01530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TVNIR_RS01550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TVNIR_RS01555	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TVNIR_RS01560	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TVNIR_RS01565	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TVNIR_RS01570	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
TVNIR_RS01575	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TVNIR_RS01580	COG0126	phosphoglycerate kinase activity
TVNIR_RS01585	COG0469	pyruvate kinase activity
TVNIR_RS01590	COG0191	fructose-bisphosphate aldolase activity
TVNIR_RS01600	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
TVNIR_RS01605	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TVNIR_RS01610	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TVNIR_RS01615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
TVNIR_RS01620	COG2813	Specifically methylates the guanine in position
TVNIR_RS01640	COG0546	phosphoglycolate phosphatase activity
TVNIR_RS01665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TVNIR_RS01670	COG0134	indole-3-glycerol-phosphate synthase activity
TVNIR_RS01680	COG1765	OsmC-like protein
TVNIR_RS01685	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TVNIR_RS01690	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
TVNIR_RS01735	COG1595	DNA-templated transcription, initiation
TVNIR_RS01750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TVNIR_RS01755	COG3178	'Phosphotransferase
TVNIR_RS01760	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
TVNIR_RS01770	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TVNIR_RS01775	COG1166	arginine decarboxylase activity
TVNIR_RS01780	COG1217	gtp-binding protein TYPA
TVNIR_RS01785	COG4970	Tfp pilus assembly protein FimT
TVNIR_RS01820	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TVNIR_RS01835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TVNIR_RS01840	COG2003	Belongs to the UPF0758 family
TVNIR_RS01850	COG2210	Belongs to the sulfur carrier protein TusA family
TVNIR_RS01865	COG0156	8-amino-7-oxononanoate synthase activity
TVNIR_RS01870	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TVNIR_RS01885	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TVNIR_RS01890	COG2885	chlorophyll binding
TVNIR_RS01895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TVNIR_RS01905	COG0408	coproporphyrinogen oxidase activity
TVNIR_RS01910	COG0009	L-threonylcarbamoyladenylate synthase
TVNIR_RS01920	COG2922	Belongs to the Smg family
TVNIR_RS01925	COG0758	DNA mediated transformation
TVNIR_RS01935	COG0242	peptide deformylase activity
TVNIR_RS01940	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TVNIR_RS01945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TVNIR_RS01955	COG5000	phosphorelay sensor kinase activity
TVNIR_RS01960	COG2204	response regulator
TVNIR_RS01965	COG0569	domain protein
TVNIR_RS01985	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TVNIR_RS01990	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
TVNIR_RS02000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TVNIR_RS02010	COG0516	GMP reductase activity
TVNIR_RS02010	COG0517	IMP dehydrogenase activity
TVNIR_RS02025	COG0004	ammonium transporteR
TVNIR_RS02030	COG0577	efflux transmembrane transporter activity
TVNIR_RS02030	COG1136	(ABC) transporter
TVNIR_RS02035	COG0390	transport system, permease component
TVNIR_RS02060	COG1309	transcriptional regulator
TVNIR_RS02070	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
TVNIR_RS02070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TVNIR_RS02080	COG0189	ligase activity
TVNIR_RS02080	COG0569	domain protein
TVNIR_RS02090	COG0583	DNA-binding transcription factor activity
TVNIR_RS02095	COG3264	Mechanosensitive ion channel
TVNIR_RS02095	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
TVNIR_RS02110	COG0129	dihydroxy-acid dehydratase activity
TVNIR_RS02130	COG3263	regulation of cellular component size
TVNIR_RS02155	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
TVNIR_RS02160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TVNIR_RS02170	COG2264	protein methyltransferase activity
TVNIR_RS02175	COG0439	Biotin carboxylase
TVNIR_RS02180	COG0511	ligase activity, forming carbon-carbon bonds
TVNIR_RS02190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TVNIR_RS02195	COG4232	protein-disulfide reductase activity
TVNIR_RS02200	COG1324	tolerance protein
TVNIR_RS02220	COG3030	protein affecting phage T7 exclusion by the F plasmid
TVNIR_RS02225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TVNIR_RS02230	COG0459	protein refolding
TVNIR_RS02235	COG3047	cAMP biosynthetic process
TVNIR_RS02235	COG2885	chlorophyll binding
TVNIR_RS02260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TVNIR_RS02270	COG0577	efflux transmembrane transporter activity
TVNIR_RS02270	COG1136	(ABC) transporter
TVNIR_RS02285	COG2911	Protein conserved in bacteria
TVNIR_RS02290	COG0729	surface antigen
TVNIR_RS02295	COG3842	ATPase activity
TVNIR_RS02300	COG1178	ABC-type Fe3 transport system permease component
TVNIR_RS02305	COG1840	ABC-type Fe3 transport system, periplasmic component
TVNIR_RS02310	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
TVNIR_RS02325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TVNIR_RS02340	COG3744	PilT protein domain protein
TVNIR_RS02370	COG1396	sequence-specific DNA binding
TVNIR_RS02385	COG1487	ribonuclease activity
TVNIR_RS02480	COG3275	phosphorelay sensor kinase activity
TVNIR_RS02495	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TVNIR_RS02500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TVNIR_RS02505	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TVNIR_RS02545	COG0446	pyridine nucleotide-disulphide oxidoreductase
TVNIR_RS02570	COG2205	protein histidine kinase activity
TVNIR_RS02595	COG0189	ligase activity
TVNIR_RS02595	COG4067	protein conserved in archaea
TVNIR_RS02600	COG1560	Kdo2-lipid A biosynthetic process
TVNIR_RS02610	COG2226	methyltransferase
TVNIR_RS02615	COG1132	(ABC) transporter
TVNIR_RS02625	COG0659	secondary active sulfate transmembrane transporter activity
TVNIR_RS02635	COG2200	EAL domain
TVNIR_RS02660	COG1028	Short-chain dehydrogenase reductase Sdr
TVNIR_RS02675	COG1671	Belongs to the UPF0178 family
TVNIR_RS02705	COG1918	ferrous iron import across plasma membrane
TVNIR_RS02705	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TVNIR_RS02750	COG1116	anion transmembrane transporter activity
TVNIR_RS02765	COG4771	TonB-dependent receptor
TVNIR_RS02770	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TVNIR_RS02775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TVNIR_RS02780	COG4558	Periplasmic binding protein
TVNIR_RS02785	COG3720	iron ion transport
TVNIR_RS02795	COG4206	TonB-dependent receptor
TVNIR_RS02855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TVNIR_RS02860	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TVNIR_RS02895	COG3077	Addiction module antitoxin, RelB DinJ family
TVNIR_RS02900	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TVNIR_RS02905	COG3077	Addiction module antitoxin, RelB DinJ family
TVNIR_RS02915	COG1598	PFAM Uncharacterised protein family UPF0150
TVNIR_RS02930	COG3609	addiction module antidote protein, CC2985 family
TVNIR_RS02945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TVNIR_RS02960	COG3077	Addiction module antitoxin, RelB DinJ family
TVNIR_RS02970	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
TVNIR_RS02980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TVNIR_RS03020	COG3657	addiction module killer protein
TVNIR_RS03035	COG1598	PFAM Uncharacterised protein family UPF0150
TVNIR_RS03065	COG3077	Addiction module antitoxin, RelB DinJ family
TVNIR_RS03115	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TVNIR_RS03130	COG1598	PFAM Uncharacterised protein family UPF0150
TVNIR_RS03145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TVNIR_RS03160	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
TVNIR_RS03175	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TVNIR_RS03195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TVNIR_RS03285	COG2944	sequence-specific DNA binding
TVNIR_RS03295	COG1434	Gram-negative-bacterium-type cell wall biogenesis
TVNIR_RS03305	COG1598	PFAM Uncharacterised protein family UPF0150
TVNIR_RS03385	COG2944	sequence-specific DNA binding
TVNIR_RS03395	COG1434	Gram-negative-bacterium-type cell wall biogenesis
TVNIR_RS03445	COG1434	Gram-negative-bacterium-type cell wall biogenesis
TVNIR_RS03545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
TVNIR_RS03560	COG1598	PFAM Uncharacterised protein family UPF0150
TVNIR_RS03590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TVNIR_RS03595	COG1086	Polysaccharide biosynthesis protein
TVNIR_RS03605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TVNIR_RS03610	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TVNIR_RS03640	COG3409	Peptidoglycan-binding domain 1 protein
TVNIR_RS03640	COG3267	Type II secretory pathway component ExeA
TVNIR_RS03665	COG3311	Transcriptional regulator
TVNIR_RS03695	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TVNIR_RS03700	COG3153	acetyltransferase
TVNIR_RS03750	COG0678	peroxiredoxin activity
TVNIR_RS03750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
TVNIR_RS03760	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TVNIR_RS03765	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TVNIR_RS03770	COG0537	adenosine 5'-monophosphoramidase activity
TVNIR_RS03795	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
TVNIR_RS03825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TVNIR_RS03835	COG0481	GTPase activity
TVNIR_RS03840	COG0681	Belongs to the peptidase S26 family
TVNIR_RS03850	COG0571	ribonuclease III activity
TVNIR_RS03855	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TVNIR_RS03865	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
TVNIR_RS03870	COG0736	holo-[acyl-carrier-protein] synthase activity
TVNIR_RS03885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TVNIR_RS03890	COG0811	peptide transport
TVNIR_RS03895	COG0848	biopolymer transport protein
TVNIR_RS03900	COG1132	(ABC) transporter
TVNIR_RS03910	COG1663	tetraacyldisaccharide 4'-kinase activity
TVNIR_RS03915	COG2835	tetraacyldisaccharide 4'-kinase activity
TVNIR_RS03920	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
TVNIR_RS03935	COG3128	pkhd-type hydroxylase
TVNIR_RS03945	COG1797	cobyrinic acid a,c-diamide synthase activity
TVNIR_RS03980	COG2920	part of a sulfur-relay system
TVNIR_RS03990	COG2923	Belongs to the DsrF TusC family
TVNIR_RS03995	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
TVNIR_RS04000	COG2221	Nitrite and sulphite reductase 4Fe-4S
TVNIR_RS04005	COG2221	Nitrite and sulphite reductase 4Fe-4S
TVNIR_RS04025	COG2920	part of a sulfur-relay system
TVNIR_RS04060	COG0105	UTP biosynthetic process
TVNIR_RS04065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TVNIR_RS04080	COG0124	histidyl-tRNA synthetase
TVNIR_RS04095	COG1160	GTP binding
TVNIR_RS04100	COG0436	Aminotransferase
TVNIR_RS04110	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
TVNIR_RS04120	COG0215	cysteine-tRNA ligase activity
TVNIR_RS04125	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TVNIR_RS04135	COG2988	succinylglutamate desuccinylase activity
TVNIR_RS04170	COG0545	Peptidyl-prolyl cis-trans isomerase
TVNIR_RS04190	COG0581	inorganic phosphate transmembrane transporter activity
TVNIR_RS04195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TVNIR_RS04200	COG0704	Plays a role in the regulation of phosphate uptake
TVNIR_RS04205	COG0737	Belongs to the 5'-nucleotidase family
TVNIR_RS04215	COG0058	SHG alpha-glucan phosphorylase activity
TVNIR_RS04230	COG1741	Belongs to the pirin family
TVNIR_RS04240	COG3093	addiction module antidote protein HigA
TVNIR_RS04250	COG4584	PFAM Integrase catalytic
TVNIR_RS04260	COG4974	Belongs to the 'phage' integrase family
TVNIR_RS04270	COG4974	Belongs to the 'phage' integrase family
TVNIR_RS04275	COG1484	DNA-dependent DNA replication
TVNIR_RS04305	COG1061	Type III restriction enzyme res subunit
TVNIR_RS04360	COG0709	Synthesizes selenophosphate from selenide and ATP
TVNIR_RS04365	COG3639	organic phosphonate transmembrane transporter activity
TVNIR_RS04370	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
TVNIR_RS04380	COG3276	selenocysteine insertion sequence binding
TVNIR_RS04400	COG1047	Peptidyl-prolyl cis-trans
TVNIR_RS04420	COG0437	4 iron, 4 sulfur cluster binding
TVNIR_RS04425	COG0243	molybdopterin cofactor binding
TVNIR_RS04435	COG4636	protein conserved in cyanobacteria
TVNIR_RS04445	COG4191	Histidine kinase
TVNIR_RS04455	COG2897	thiosulfate sulfurtransferase activity
TVNIR_RS04475	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TVNIR_RS04510	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
TVNIR_RS04530	COG0437	4 iron, 4 sulfur cluster binding
TVNIR_RS04535	COG0243	molybdopterin cofactor binding
TVNIR_RS04545	COG2864	formate dehydrogenase
TVNIR_RS04550	COG0437	4 iron, 4 sulfur cluster binding
TVNIR_RS04555	COG3383	formate dehydrogenase (NAD+) activity
TVNIR_RS04555	COG0243	molybdopterin cofactor binding
TVNIR_RS04560	COG3383	formate dehydrogenase (NAD+) activity
TVNIR_RS04560	COG0243	molybdopterin cofactor binding
TVNIR_RS04585	COG0671	phosphoesterase, PA-phosphatase related
TVNIR_RS04595	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TVNIR_RS04625	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
TVNIR_RS04660	COG0069	glutamate synthase activity
TVNIR_RS04700	COG1924	4 iron, 4 sulfur cluster binding
TVNIR_RS04740	COG4977	sequence-specific DNA binding
TVNIR_RS04740	COG1917	Cupin 2, conserved barrel domain protein
TVNIR_RS04750	COG2210	Belongs to the sulfur carrier protein TusA family
TVNIR_RS04765	COG3220	belongs to the UPF0276 family
TVNIR_RS04800	COG1960	acyl-CoA dehydrogenase activity
TVNIR_RS04810	COG1024	Enoyl-CoA hydratase
TVNIR_RS04810	COG1250	3-hydroxyacyl-CoA dehydrogenase
TVNIR_RS04815	COG1022	Amp-dependent synthetase and ligase
TVNIR_RS04825	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TVNIR_RS04830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TVNIR_RS04835	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TVNIR_RS04880	COG2205	protein histidine kinase activity
TVNIR_RS04900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TVNIR_RS04920	COG3079	Belongs to the UPF0149 family
TVNIR_RS04925	COG0006	proline dipeptidase activity
TVNIR_RS04930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TVNIR_RS04935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TVNIR_RS04940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TVNIR_RS04950	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TVNIR_RS04955	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TVNIR_RS04960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
TVNIR_RS04970	COG1121	(ABC) transporter
TVNIR_RS04975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TVNIR_RS04990	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
TVNIR_RS04995	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TVNIR_RS05000	COG1331	Highly conserved protein containing a thioredoxin domain
TVNIR_RS05060	COG0588	phosphoglycerate mutase activity
TVNIR_RS05065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TVNIR_RS05085	COG0318	PFAM AMP-dependent synthetase and ligase
TVNIR_RS05105	COG5002	protein histidine kinase activity
TVNIR_RS05115	COG2217	Heavy metal translocating P-type atpase
TVNIR_RS05130	COG2132	Multicopper oxidase
TVNIR_RS05150	COG0537	adenosine 5'-monophosphoramidase activity
TVNIR_RS05165	COG3387	PFAM Glycoside hydrolase 15-related
TVNIR_RS05195	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
TVNIR_RS05200	COG1140	nitrate reductase beta subunit
TVNIR_RS05325	COG0210	DNA helicase
TVNIR_RS05355	COG4636	protein conserved in cyanobacteria
TVNIR_RS05360	COG2161	toxin-antitoxin pair type II binding
TVNIR_RS05395	COG0471	metal ion transport
TVNIR_RS05395	COG3273	potassium ion transport
TVNIR_RS05400	COG1247	-acetyltransferase
TVNIR_RS05410	COG1216	Glycosyl transferase, family 2
TVNIR_RS05450	COG3012	SEC-C Motif Domain Protein
TVNIR_RS05450	COG3318	Belongs to the UPF0149 family
TVNIR_RS05455	COG0418	dihydroorotase activity
TVNIR_RS05470	COG0446	pyridine nucleotide-disulphide oxidoreductase
TVNIR_RS05485	COG0433	COG0433 Predicted ATPase
TVNIR_RS05535	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
TVNIR_RS05545	COG1175	transmembrane transport
TVNIR_RS05550	COG0395	ABC-type sugar transport system, permease component
TVNIR_RS05555	COG3842	ATPase activity
TVNIR_RS05565	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TVNIR_RS05585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TVNIR_RS05590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TVNIR_RS05600	COG1752	Esterase of the alpha-beta hydrolase superfamily
TVNIR_RS05630	COG1522	sequence-specific DNA binding
TVNIR_RS05635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TVNIR_RS05640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TVNIR_RS05645	COG0066	3-isopropylmalate dehydratase activity
TVNIR_RS05650	COG0473	3-isopropylmalate dehydrogenase activity
TVNIR_RS05655	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
TVNIR_RS05675	COG0135	phosphoribosylanthranilate isomerase activity
TVNIR_RS05680	COG0133	tryptophan synthase activity
TVNIR_RS05685	COG0159	tryptophan synthase activity
TVNIR_RS05690	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TVNIR_RS05695	COG0285	dihydrofolate synthase activity
TVNIR_RS05705	COG1286	toxin biosynthetic process
TVNIR_RS05715	COG1376	ErfK ybiS ycfS ynhG family protein
TVNIR_RS05720	COG1959	2 iron, 2 sulfur cluster binding
TVNIR_RS05735	COG0714	Associated with various cellular activities
TVNIR_RS05740	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TVNIR_RS05745	COG1127	ABC transporter
TVNIR_RS05750	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
TVNIR_RS05750	COG3008	intermembrane lipid transfer
TVNIR_RS05765	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
TVNIR_RS05770	COG1028	Short-chain dehydrogenase reductase Sdr
TVNIR_RS05780	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
TVNIR_RS05785	COG0183	Belongs to the thiolase family
TVNIR_RS05795	COG3243	poly(R)-hydroxyalkanoic acid synthase
TVNIR_RS05800	COG0788	formyltetrahydrofolate deformylase activity
TVNIR_RS05820	COG3550	peptidyl-serine autophosphorylation
TVNIR_RS05840	COG0210	DNA helicase
TVNIR_RS05860	COG0430	RNA-3'-phosphate cyclase activity
TVNIR_RS05865	COG1234	tRNA 3'-trailer cleavage
TVNIR_RS05895	COG1053	succinate dehydrogenase
TVNIR_RS05900	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TVNIR_RS05905	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TVNIR_RS05910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TVNIR_RS05945	COG0121	glutamine amidotransferase
TVNIR_RS05950	COG2062	phosphohistidine phosphatase, SixA
TVNIR_RS05965	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TVNIR_RS05970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TVNIR_RS05980	COG0471	metal ion transport
TVNIR_RS06005	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
TVNIR_RS06010	COG2943	transferase activity, transferring hexosyl groups
TVNIR_RS06015	COG3038	cytochrome b561
TVNIR_RS06025	COG3273	potassium ion transport
TVNIR_RS06025	COG0471	metal ion transport
TVNIR_RS06060	COG0501	Belongs to the peptidase M48B family
TVNIR_RS06100	COG2078	PFAM AMMECR1 domain protein
TVNIR_RS06100	COG3885	ferrous iron binding
TVNIR_RS06105	COG1355	regulation of microtubule-based process
TVNIR_RS06115	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TVNIR_RS06115	COG1024	Enoyl-CoA hydratase
TVNIR_RS06145	COG0310	cobalt ion transport
TVNIR_RS06155	COG1122	ATPase activity
TVNIR_RS06160	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TVNIR_RS06175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TVNIR_RS06180	COG2267	carboxylic ester hydrolase activity
TVNIR_RS06200	COG0437	4 iron, 4 sulfur cluster binding
TVNIR_RS06205	COG0348	domain, Protein
TVNIR_RS06215	COG2226	methyltransferase
TVNIR_RS06225	COG1872	DUF167
TVNIR_RS06240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TVNIR_RS06255	COG0517	IMP dehydrogenase activity
TVNIR_RS06260	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TVNIR_RS06295	COG2409	Drug exporters of the RND superfamily
TVNIR_RS06320	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TVNIR_RS06325	COG4139	cobalamin transport
TVNIR_RS06330	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TVNIR_RS06335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TVNIR_RS06355	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TVNIR_RS06360	COG3657	addiction module killer protein
TVNIR_RS06370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TVNIR_RS06375	COG4566	intracellular signal transduction
TVNIR_RS06400	COG0424	maF-like protein
TVNIR_RS06405	COG5016	pyruvate
TVNIR_RS06405	COG0511	ligase activity, forming carbon-carbon bonds
TVNIR_RS06410	COG0439	Biotin carboxylase
TVNIR_RS06420	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TVNIR_RS06425	COG0416	fatty acid biosynthetic process
TVNIR_RS06430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TVNIR_RS06435	COG2954	triphosphatase activity
TVNIR_RS06440	COG1573	uracil-dna glycosylase
TVNIR_RS06445	COG0322	excinuclease ABC activity
TVNIR_RS06450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TVNIR_RS06465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TVNIR_RS06510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TVNIR_RS06520	COG0372	Belongs to the citrate synthase family
TVNIR_RS06525	COG1335	isochorismatase
TVNIR_RS06610	COG0850	regulation of cytokinetic process
TVNIR_RS06615	COG2894	cell division
TVNIR_RS06620	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
TVNIR_RS06625	COG2738	Putative neutral zinc metallopeptidase
TVNIR_RS06630	COG0668	transmembrane transport
TVNIR_RS06635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TVNIR_RS06640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TVNIR_RS06650	COG1070	Carbohydrate kinase
TVNIR_RS06655	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
TVNIR_RS06660	COG1196	nuclear chromosome segregation
TVNIR_RS06665	COG3115	cell septum assembly
TVNIR_RS06670	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TVNIR_RS06675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TVNIR_RS06680	COG2350	Protein conserved in bacteria
TVNIR_RS06685	COG0009	L-threonylcarbamoyladenylate synthase
TVNIR_RS06690	COG1994	Peptidase M50
TVNIR_RS06700	COG0180	Tryptophanyl-tRNA synthetase
TVNIR_RS06710	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TVNIR_RS06720	COG0521	Mo-molybdopterin cofactor biosynthetic process
TVNIR_RS06745	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TVNIR_RS06760	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TVNIR_RS06775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
TVNIR_RS06780	COG1053	succinate dehydrogenase
TVNIR_RS06790	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
TVNIR_RS06800	COG0033	Phosphoglucomutase
TVNIR_RS06810	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TVNIR_RS06815	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TVNIR_RS06820	COG1058	Belongs to the CinA family
TVNIR_RS06820	COG1546	Belongs to the CinA family
TVNIR_RS06825	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TVNIR_RS06830	COG2137	regulation of response to DNA damage stimulus
TVNIR_RS06835	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TVNIR_RS06845	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
TVNIR_RS06865	COG1337	RAMP superfamily
TVNIR_RS06900	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TVNIR_RS06975	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TVNIR_RS06980	COG1518	maintenance of DNA repeat elements
TVNIR_RS06990	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TVNIR_RS07035	COG5001	Diguanylate cyclase
TVNIR_RS07035	COG3300	MHYT domain
TVNIR_RS07050	COG0071	Belongs to the small heat shock protein (HSP20) family
TVNIR_RS07065	COG0488	(ABC) transporter
TVNIR_RS07090	COG0167	dihydroorotate dehydrogenase activity
TVNIR_RS07110	COG1028	Short-chain dehydrogenase reductase Sdr
TVNIR_RS07115	COG4191	Histidine kinase
TVNIR_RS07120	COG4566	intracellular signal transduction
TVNIR_RS07125	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
TVNIR_RS07130	COG1562	ergosterol biosynthetic process
TVNIR_RS07140	COG1322	Protein conserved in bacteria
TVNIR_RS07150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TVNIR_RS07155	COG0402	S-adenosylhomocysteine deaminase activity
TVNIR_RS07180	COG0259	pyridoxamine-phosphate oxidase activity
TVNIR_RS07195	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
TVNIR_RS07195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TVNIR_RS07200	COG0739	heme binding
TVNIR_RS07205	COG0842	Transport permease protein
TVNIR_RS07210	COG1131	(ABC) transporter
TVNIR_RS07215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TVNIR_RS07220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TVNIR_RS07255	COG0446	pyridine nucleotide-disulphide oxidoreductase
TVNIR_RS07265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TVNIR_RS07285	COG0070	glutamate synthase
TVNIR_RS07285	COG0067	glutamate synthase
TVNIR_RS07285	COG0069	glutamate synthase activity
TVNIR_RS07300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TVNIR_RS07315	COG2217	Heavy metal translocating P-type atpase
TVNIR_RS07325	COG2863	cytochrome
TVNIR_RS07365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TVNIR_RS07370	COG2850	peptidyl-arginine hydroxylation
TVNIR_RS07390	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TVNIR_RS07395	COG2915	High frequency lysogenization protein hflD homolog
TVNIR_RS07400	COG0482	sulfurtransferase activity
TVNIR_RS07415	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
TVNIR_RS07420	COG0542	response to heat
TVNIR_RS07425	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TVNIR_RS07435	COG1028	Short-chain dehydrogenase reductase Sdr
TVNIR_RS07440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TVNIR_RS07445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TVNIR_RS07450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TVNIR_RS07455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TVNIR_RS07460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TVNIR_RS07465	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TVNIR_RS07485	COG1509	lysine 2,3-aminomutase activity
TVNIR_RS07545	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
TVNIR_RS07560	COG1472	Belongs to the glycosyl hydrolase 3 family
TVNIR_RS07575	COG0436	Aminotransferase
TVNIR_RS07585	COG1335	isochorismatase
TVNIR_RS07615	COG3548	integral membrane protein
TVNIR_RS07635	COG1136	(ABC) transporter
TVNIR_RS07635	COG0577	efflux transmembrane transporter activity
TVNIR_RS07640	COG1136	(ABC) transporter
TVNIR_RS07675	COG4953	penicillin-binding protein 1C
TVNIR_RS07680	COG2373	Large extracellular alpha-helical protein
TVNIR_RS07695	COG0348	domain, Protein
TVNIR_RS07695	COG3901	Regulator of nitric oxide reductase transcription
TVNIR_RS07710	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
TVNIR_RS07740	COG1522	sequence-specific DNA binding
TVNIR_RS07760	COG0535	radical SAM domain protein
TVNIR_RS07775	COG4974	Belongs to the 'phage' integrase family
TVNIR_RS07780	COG0517	IMP dehydrogenase activity
TVNIR_RS07800	COG0714	Associated with various cellular activities
TVNIR_RS07820	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
TVNIR_RS07840	COG0318	PFAM AMP-dependent synthetase and ligase
TVNIR_RS07845	COG2050	protein possibly involved in aromatic compounds catabolism
TVNIR_RS07850	COG1752	Esterase of the alpha-beta hydrolase superfamily
TVNIR_RS07895	COG1104	cysteine desulfurase activity
TVNIR_RS07905	COG0602	queuosine metabolic process
TVNIR_RS07910	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TVNIR_RS07960	COG1715	Restriction endonuclease
TVNIR_RS07965	COG0517	IMP dehydrogenase activity
TVNIR_RS07970	COG4974	Belongs to the 'phage' integrase family
TVNIR_RS08015	COG0446	pyridine nucleotide-disulphide oxidoreductase
TVNIR_RS08035	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TVNIR_RS08045	COG0398	Pfam SNARE associated Golgi protein
TVNIR_RS08060	COG3608	succinylglutamate desuccinylase aspartoacylase
TVNIR_RS08060	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
TVNIR_RS08065	COG1529	Aldehyde oxidase and xanthine dehydrogenase
TVNIR_RS08070	COG2080	2 iron, 2 sulfur cluster binding
TVNIR_RS08100	COG4636	protein conserved in cyanobacteria
TVNIR_RS08120	COG4636	protein conserved in cyanobacteria
TVNIR_RS08170	COG3179	chitinase
TVNIR_RS08220	COG2920	part of a sulfur-relay system
TVNIR_RS08225	COG2181	nitrate reductase activity
TVNIR_RS08230	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
TVNIR_RS08235	COG1140	nitrate reductase beta subunit
TVNIR_RS08240	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
TVNIR_RS08245	COG2223	nitrite transmembrane transporter activity
TVNIR_RS08260	COG3850	Histidine kinase
TVNIR_RS08265	COG2197	response regulator
TVNIR_RS08270	COG2920	part of a sulfur-relay system
TVNIR_RS08285	COG0516	GMP reductase activity
TVNIR_RS08285	COG0517	IMP dehydrogenase activity
TVNIR_RS08305	COG2221	Nitrite and sulphite reductase 4Fe-4S
TVNIR_RS08310	COG2221	Nitrite and sulphite reductase 4Fe-4S
TVNIR_RS08340	COG0826	peptidase U32
TVNIR_RS08345	COG0826	peptidase U32
TVNIR_RS08350	COG3154	lipid carrier protein
TVNIR_RS08365	COG0523	cobalamin synthesis protein
TVNIR_RS08395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TVNIR_RS08405	COG2974	May be involved in recombination
TVNIR_RS08460	COG1210	Utp--glucose-1-phosphate uridylyltransferase
TVNIR_RS08465	COG1555	photosystem II stabilization
TVNIR_RS08465	COG1596	polysaccharide export
TVNIR_RS08470	COG0284	orotidine-5'-phosphate decarboxylase activity
TVNIR_RS08475	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
TVNIR_RS08480	COG0776	regulation of translation
TVNIR_RS08490	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TVNIR_RS08495	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TVNIR_RS08500	COG0287	Prephenate dehydrogenase
TVNIR_RS08520	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
TVNIR_RS08530	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TVNIR_RS08535	COG0658	competence protein
TVNIR_RS08535	COG2333	competence protein COMEC
TVNIR_RS08545	COG1136	(ABC) transporter
TVNIR_RS08550	COG4591	ABC-type transport system involved in lipoprotein release permease component
TVNIR_RS08560	COG2957	Belongs to the agmatine deiminase family
TVNIR_RS08565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TVNIR_RS08575	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
TVNIR_RS08600	COG1530	ribonuclease E activity
TVNIR_RS08605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TVNIR_RS08610	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TVNIR_RS08610	COG0047	phosphoribosylformylglycinamidine synthase activity
TVNIR_RS08625	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TVNIR_RS08630	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TVNIR_RS08635	COG0316	Belongs to the HesB IscA family
TVNIR_RS08645	COG2151	metal-sulfur cluster biosynthetic enzyme
TVNIR_RS08650	COG0719	Fe-S assembly protein
TVNIR_RS08655	COG0396	ATPase activity
TVNIR_RS08660	COG2166	iron-sulfur cluster assembly
TVNIR_RS08665	COG0719	Fe-S assembly protein
TVNIR_RS08670	COG1959	2 iron, 2 sulfur cluster binding
TVNIR_RS08675	COG2105	PFAM AIG2 family protein
TVNIR_RS08680	COG2171	N-acyltransferase activity
TVNIR_RS08685	COG1393	Belongs to the ArsC family
TVNIR_RS08695	COG2084	Dehydrogenase
TVNIR_RS08700	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TVNIR_RS08715	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
TVNIR_RS08735	COG1196	nuclear chromosome segregation
TVNIR_RS08800	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TVNIR_RS08805	COG0569	domain protein
TVNIR_RS08820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TVNIR_RS08845	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TVNIR_RS08855	COG0095	Lipoate-protein ligase
TVNIR_RS08860	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TVNIR_RS08865	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
TVNIR_RS08870	COG0148	phosphopyruvate hydratase activity
TVNIR_RS08875	COG2877	3-deoxy-8-phosphooctulonate synthase activity
TVNIR_RS08880	COG0504	CTP synthase activity
TVNIR_RS08890	COG0825	malonyl-CoA metabolic process
TVNIR_RS08900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TVNIR_RS08905	COG0673	inositol 2-dehydrogenase activity
TVNIR_RS08915	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TVNIR_RS08935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TVNIR_RS08995	COG1216	Glycosyl transferase, family 2
TVNIR_RS09000	COG1450	Type ii and iii secretion system protein
TVNIR_RS09025	COG4795	General secretion pathway protein
TVNIR_RS09030	COG2165	general secretion pathway protein
TVNIR_RS09045	COG1459	type II secretion system
TVNIR_RS09050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
TVNIR_RS09055	COG0438	transferase activity, transferring glycosyl groups
TVNIR_RS09060	COG1216	Glycosyl transferase, family 2
TVNIR_RS09065	COG1088	dTDP-glucose 4,6-dehydratase activity
TVNIR_RS09095	COG4717	serine-type aminopeptidase activity
TVNIR_RS09100	COG0420	3'-5' exonuclease activity
TVNIR_RS09120	COG1388	LysM domain
TVNIR_RS09120	COG0741	lytic transglycosylase activity
TVNIR_RS09125	COG2989	Protein conserved in bacteria
TVNIR_RS09140	COG1007	ATP synthesis coupled electron transport
TVNIR_RS09150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TVNIR_RS09155	COG0713	ATP synthesis coupled electron transport
TVNIR_RS09165	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TVNIR_RS09170	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TVNIR_RS09175	COG1034	ATP synthesis coupled electron transport
TVNIR_RS09190	COG0649	NAD binding
TVNIR_RS09200	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TVNIR_RS09205	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TVNIR_RS09210	COG0058	SHG alpha-glucan phosphorylase activity
TVNIR_RS09220	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TVNIR_RS09225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TVNIR_RS09230	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TVNIR_RS09250	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TVNIR_RS09255	COG0575	Belongs to the CDS family
TVNIR_RS09260	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TVNIR_RS09265	COG0233	cytoplasmic translational termination
TVNIR_RS09270	COG0528	UMP kinase activity
TVNIR_RS09275	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TVNIR_RS09280	COG0052	Belongs to the universal ribosomal protein uS2 family
TVNIR_RS09285	COG0024	Methionine aminopeptidase
TVNIR_RS09290	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
TVNIR_RS09300	COG1643	Atp-dependent helicase
TVNIR_RS09355	COG4181	ATPase activity
TVNIR_RS09365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TVNIR_RS09400	COG2133	pyrroloquinoline quinone binding
TVNIR_RS09435	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TVNIR_RS09475	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TVNIR_RS09480	COG0674	pyruvate-flavodoxin oxidoreductase activity
TVNIR_RS09485	COG1013	pyruvate-flavodoxin oxidoreductase activity
TVNIR_RS09495	COG0306	phosphate transporter
TVNIR_RS09520	COG4133	protoheme IX ABC transporter activity
TVNIR_RS09540	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
TVNIR_RS09575	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
TVNIR_RS09595	COG0409	Hydrogenase expression formation protein
TVNIR_RS09615	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
TVNIR_RS09630	COG0375	protein maturation
TVNIR_RS09635	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
TVNIR_RS09640	COG1773	rubredoxin
TVNIR_RS09650	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
TVNIR_RS09690	COG1575	Belongs to the MenA family. Type 1 subfamily
TVNIR_RS09695	COG0702	epimerase
TVNIR_RS09720	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
TVNIR_RS09730	COG0741	lytic transglycosylase activity
TVNIR_RS09780	COG3300	MHYT domain
TVNIR_RS09780	COG5001	Diguanylate cyclase
TVNIR_RS09820	COG3657	addiction module killer protein
TVNIR_RS09825	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TVNIR_RS09905	COG0582	viral genome integration into host DNA
TVNIR_RS09925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TVNIR_RS09935	COG0742	ribosomal rna small subunit methyltransferase
TVNIR_RS09960	COG1666	GTP binding
TVNIR_RS09965	COG2363	Small membrane protein
TVNIR_RS09980	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TVNIR_RS10005	COG1222	aaa ATPase
TVNIR_RS10125	COG1376	ErfK ybiS ycfS ynhG family protein
TVNIR_RS10140	COG0438	transferase activity, transferring glycosyl groups
TVNIR_RS10145	COG0438	transferase activity, transferring glycosyl groups
TVNIR_RS10150	COG0463	Glycosyl transferase, family 2
TVNIR_RS10165	COG0859	PFAM glycosyl transferase family 9
TVNIR_RS10190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TVNIR_RS10200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TVNIR_RS10215	COG3278	Belongs to the heme-copper respiratory oxidase family
TVNIR_RS10230	COG2010	Cytochrome c
TVNIR_RS10250	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TVNIR_RS10265	COG4797	methyltransferase
TVNIR_RS10265	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TVNIR_RS10270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TVNIR_RS10280	COG1295	ribonuclease BN
TVNIR_RS10295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TVNIR_RS10310	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TVNIR_RS10315	COG0321	lipoyl(octanoyl) transferase activity
TVNIR_RS10320	COG2921	Belongs to the UPF0250 family
TVNIR_RS10325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TVNIR_RS10330	COG1686	Belongs to the peptidase S11 family
TVNIR_RS10340	COG2951	lytic endotransglycosylase activity
TVNIR_RS10345	COG0772	Belongs to the SEDS family
TVNIR_RS10350	COG0768	penicillin binding
TVNIR_RS10355	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
TVNIR_RS10360	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
TVNIR_RS10365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TVNIR_RS10370	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
TVNIR_RS10375	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TVNIR_RS10380	COG0837	glucose binding
TVNIR_RS10385	COG2967	ApaG domain
TVNIR_RS10390	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
TVNIR_RS10405	COG0776	regulation of translation
TVNIR_RS10410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TVNIR_RS10410	COG0072	phenylalanine-tRNA ligase activity
TVNIR_RS10415	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TVNIR_RS10420	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TVNIR_RS10425	COG0291	Belongs to the bacterial ribosomal protein bL35 family
TVNIR_RS10430	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TVNIR_RS10435	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TVNIR_RS10440	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
TVNIR_RS10465	COG1968	undecaprenyl-diphosphatase activity
TVNIR_RS10470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TVNIR_RS10475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TVNIR_RS10510	COG0277	FAD linked oxidase domain protein
TVNIR_RS10515	COG0277	FAD linked oxidase domain protein
TVNIR_RS10520	COG0247	lactate metabolic process
TVNIR_RS10525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
TVNIR_RS10535	COG0039	L-malate dehydrogenase activity
TVNIR_RS10540	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TVNIR_RS10560	COG2224	Isocitrate lyase
TVNIR_RS10565	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
TVNIR_RS10570	COG0247	lactate metabolic process
TVNIR_RS10580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TVNIR_RS10585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TVNIR_RS10590	COG1862	Preprotein translocase
TVNIR_RS10595	COG0343	queuine tRNA-ribosyltransferase activity
TVNIR_RS10600	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TVNIR_RS10620	COG1111	helicase
TVNIR_RS10620	COG1205	dead DEAH box helicase
TVNIR_RS10630	COG3177	Filamentation induced by cAMP protein fic
TVNIR_RS10705	COG1943	Transposase
TVNIR_RS10710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TVNIR_RS10715	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TVNIR_RS10770	COG0737	Belongs to the 5'-nucleotidase family
TVNIR_RS10850	COG1028	Short-chain dehydrogenase reductase Sdr
TVNIR_RS10855	COG3384	dioxygenase
TVNIR_RS10880	COG0702	epimerase
TVNIR_RS10925	COG3093	addiction module antidote protein HigA
TVNIR_RS10930	COG3344	reverse transcriptase
TVNIR_RS10990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TVNIR_RS10995	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TVNIR_RS10995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TVNIR_RS11025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TVNIR_RS11025	COG1017	nitric oxide dioxygenase activity
TVNIR_RS11030	COG3956	TIGRFAM MazG family protein
TVNIR_RS11035	COG1115	amino acid carrier protein
TVNIR_RS11110	COG0444	Belongs to the ABC transporter superfamily
TVNIR_RS11115	COG4608	Belongs to the ABC transporter superfamily
TVNIR_RS11130	COG1320	monovalent cation:proton antiporter activity
TVNIR_RS11135	COG2212	antiporter activity
TVNIR_RS11140	COG1863	multisubunit Na H antiporter MnhE subunit
TVNIR_RS11145	COG0651	ATP synthesis coupled electron transport
TVNIR_RS11150	COG1006	Multisubunit Na H antiporter MnhC subunit
TVNIR_RS11155	COG2111	Na H antiporter
TVNIR_RS11160	COG2111	Na H antiporter
TVNIR_RS11160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TVNIR_RS11165	COG4991	sh3 domain protein
TVNIR_RS11175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TVNIR_RS11180	COG0717	Belongs to the dCTP deaminase family
TVNIR_RS11185	COG0489	protein tyrosine kinase activity
TVNIR_RS11190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TVNIR_RS11190	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TVNIR_RS11195	COG0235	Class ii aldolase
TVNIR_RS11200	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
TVNIR_RS11205	COG4657	Part of a membrane complex involved in electron transport
TVNIR_RS11210	COG2878	Part of a membrane complex involved in electron transport
TVNIR_RS11220	COG4658	electron transport chain
TVNIR_RS11230	COG4660	Part of a membrane complex involved in electron transport
TVNIR_RS11240	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TVNIR_RS11260	COG0789	Transcriptional regulator
TVNIR_RS11265	COG0415	Belongs to the DNA photolyase family
TVNIR_RS11290	COG0513	Belongs to the DEAD box helicase family
TVNIR_RS11300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TVNIR_RS11300	COG0519	Catalyzes the synthesis of GMP from XMP
TVNIR_RS11355	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TVNIR_RS11360	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
TVNIR_RS11365	COG0709	Synthesizes selenophosphate from selenide and ATP
TVNIR_RS11380	COG3437	response regulator, receiver
TVNIR_RS11385	COG0243	molybdopterin cofactor binding
TVNIR_RS11390	COG2146	nitrite reductase [NAD(P)H] activity
TVNIR_RS11395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TVNIR_RS11400	COG1116	anion transmembrane transporter activity
TVNIR_RS11405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TVNIR_RS11410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TVNIR_RS11410	COG1116	anion transmembrane transporter activity
TVNIR_RS11415	COG3707	response regulator
TVNIR_RS11435	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
TVNIR_RS11440	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TVNIR_RS11455	COG2010	Cytochrome c
TVNIR_RS11460	COG0577	efflux transmembrane transporter activity
TVNIR_RS11465	COG1136	(ABC) transporter
TVNIR_RS11470	COG2239	Acts as a magnesium transporter
TVNIR_RS11475	COG2239	Acts as a magnesium transporter
TVNIR_RS11545	COG3028	Belongs to the UPF0307 family
TVNIR_RS11565	COG3028	Belongs to the UPF0307 family
TVNIR_RS11575	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
TVNIR_RS11590	COG0720	synthase
TVNIR_RS11595	COG2183	response to ionizing radiation
TVNIR_RS11655	COG1271	oxidase subunit
TVNIR_RS11660	COG1294	oxidase, subunit
TVNIR_RS11665	COG4988	ABC transporter
TVNIR_RS11670	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
TVNIR_RS11680	COG0542	response to heat
TVNIR_RS11690	COG0564	pseudouridine synthase activity
TVNIR_RS11705	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TVNIR_RS11705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TVNIR_RS11710	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
TVNIR_RS11715	COG0045	succinate-CoA ligase (ADP-forming) activity
TVNIR_RS11740	COG0745	RESPONSE REGULATOR receiver
TVNIR_RS11785	COG4964	Belongs to the GSP D family
TVNIR_RS11815	COG0577	efflux transmembrane transporter activity
TVNIR_RS11820	COG1136	(ABC) transporter
TVNIR_RS11855	COG0424	maF-like protein
TVNIR_RS11870	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TVNIR_RS11875	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TVNIR_RS11890	COG0495	leucyl-tRNA aminoacylation
TVNIR_RS11900	COG0058	SHG alpha-glucan phosphorylase activity
TVNIR_RS11905	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
TVNIR_RS11945	COG1136	(ABC) transporter
TVNIR_RS11960	COG0815	Transfers the fatty acyl group on membrane lipoproteins
TVNIR_RS11970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TVNIR_RS11975	COG1702	phosphate starvation-inducible protein PhoH
TVNIR_RS11980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TVNIR_RS11995	COG2814	Major facilitator Superfamily
TVNIR_RS12000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TVNIR_RS12005	COG0203	ribosomal protein L17
TVNIR_RS12010	COG0202	RNA polymerase activity
TVNIR_RS12015	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TVNIR_RS12020	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TVNIR_RS12025	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TVNIR_RS12030	COG0201	protein transport
TVNIR_RS12035	COG0200	Binds to the 23S rRNA
TVNIR_RS12040	COG1841	ribosomal large subunit assembly
TVNIR_RS12045	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TVNIR_RS12050	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TVNIR_RS12055	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TVNIR_RS12060	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TVNIR_RS12065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TVNIR_RS12070	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TVNIR_RS12075	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TVNIR_RS12080	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TVNIR_RS12085	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TVNIR_RS12090	COG0255	Belongs to the universal ribosomal protein uL29 family
TVNIR_RS12095	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TVNIR_RS12100	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TVNIR_RS12105	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TVNIR_RS12110	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TVNIR_RS12115	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TVNIR_RS12120	COG0089	rRNA binding
TVNIR_RS12125	COG0088	Forms part of the polypeptide exit tunnel
TVNIR_RS12130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TVNIR_RS12135	COG0051	transcription antitermination factor activity, RNA binding
TVNIR_RS12140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TVNIR_RS12145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TVNIR_RS12150	COG0049	tRNA binding
TVNIR_RS12155	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
TVNIR_RS12160	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TVNIR_RS12165	COG0085	RNA polymerase activity
TVNIR_RS12170	COG0222	ribosome binding
TVNIR_RS12175	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TVNIR_RS12180	COG0081	regulation of translation
TVNIR_RS12185	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TVNIR_RS12205	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TVNIR_RS12240	COG0237	dephospho-CoA kinase activity
TVNIR_RS12245	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
TVNIR_RS12250	COG0494	nUDIX hydrolase
TVNIR_RS12255	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TVNIR_RS12260	COG0653	protein targeting
TVNIR_RS12270	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
TVNIR_RS12275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TVNIR_RS12285	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
TVNIR_RS12290	COG1181	Belongs to the D-alanine--D-alanine ligase family
TVNIR_RS12295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TVNIR_RS12300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TVNIR_RS12305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TVNIR_RS12310	COG0772	Belongs to the SEDS family
TVNIR_RS12315	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TVNIR_RS12320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TVNIR_RS12325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TVNIR_RS12330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TVNIR_RS12340	COG3116	cell division
TVNIR_RS12345	COG0275	rRNA processing
TVNIR_RS12350	COG2001	Belongs to the MraZ family
TVNIR_RS12365	COG0792	nuclease activity
TVNIR_RS12370	COG0277	FAD linked oxidase domain protein
TVNIR_RS12375	COG2969	positive regulation of protein catabolic process
TVNIR_RS12380	COG0625	glutathione transferase activity
TVNIR_RS12385	COG2857	Cytochrome c1
TVNIR_RS12390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TVNIR_RS12395	COG0723	plastoquinol--plastocyanin reductase activity
TVNIR_RS12405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TVNIR_RS12410	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TVNIR_RS12420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
TVNIR_RS12430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TVNIR_RS12445	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
TVNIR_RS12450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TVNIR_RS12455	COG1127	ABC transporter
TVNIR_RS12490	COG1137	ATPase activity
TVNIR_RS12515	COG1660	Displays ATPase and GTPase activities
TVNIR_RS12525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TVNIR_RS12540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TVNIR_RS12555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TVNIR_RS12565	COG2853	Lipoprotein
TVNIR_RS12570	COG0137	argininosuccinate synthase activity
TVNIR_RS12580	COG1120	ATPase activity
TVNIR_RS12585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TVNIR_RS12610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TVNIR_RS12615	COG0508	dehydrogenase complex catalyzes the overall conversion of
TVNIR_RS12630	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
TVNIR_RS12635	COG0012	GTP binding
TVNIR_RS12640	COG0193	aminoacyl-tRNA hydrolase activity
TVNIR_RS12645	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TVNIR_RS12650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TVNIR_RS12660	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TVNIR_RS12675	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TVNIR_RS12680	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TVNIR_RS12695	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TVNIR_RS12700	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
TVNIR_RS12705	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TVNIR_RS12710	COG0154	amidase activity
TVNIR_RS12715	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TVNIR_RS12720	COG1077	Cell shape determining protein MreB Mrl
TVNIR_RS12725	COG1792	Involved in formation and maintenance of cell shape
TVNIR_RS12730	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
TVNIR_RS12735	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
TVNIR_RS12750	COG0859	PFAM glycosyl transferase family 9
TVNIR_RS12755	COG0859	PFAM glycosyl transferase family 9
TVNIR_RS12760	COG3642	lipopolysaccharide core region biosynthetic process
TVNIR_RS12765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TVNIR_RS12770	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TVNIR_RS12770	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TVNIR_RS12775	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
TVNIR_RS12785	COG1519	Transferase
TVNIR_RS12810	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TVNIR_RS12815	COG2153	protein acetylation
TVNIR_RS12825	COG0133	tryptophan synthase activity
TVNIR_RS12830	COG3850	Histidine kinase
TVNIR_RS12830	COG3850	Histidine kinase
TVNIR_RS12835	COG2197	response regulator
TVNIR_RS12845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TVNIR_RS12845	COG1648	precorrin-2 dehydrogenase activity
TVNIR_RS12865	COG0450	alkyl hydroperoxide reductase
TVNIR_RS12875	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TVNIR_RS12885	COG0328	RNA-DNA hybrid ribonuclease activity
TVNIR_RS12915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TVNIR_RS12920	COG0432	Pfam Uncharacterised protein family UPF0047
TVNIR_RS12930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TVNIR_RS12945	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TVNIR_RS12955	COG1858	cytochrome C peroxidase
TVNIR_RS12975	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
TVNIR_RS12990	COG4206	TonB-dependent receptor
TVNIR_RS13000	COG0446	pyridine nucleotide-disulphide oxidoreductase
TVNIR_RS13010	COG2204	response regulator
TVNIR_RS13015	COG3852	Histidine kinase
TVNIR_RS13030	COG1136	(ABC) transporter
TVNIR_RS13035	COG4591	ABC-type transport system involved in lipoprotein release permease component
TVNIR_RS13040	COG1136	(ABC) transporter
TVNIR_RS13045	COG0577	efflux transmembrane transporter activity
TVNIR_RS13065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TVNIR_RS13070	COG2095	MarC family integral membrane protein
TVNIR_RS13110	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TVNIR_RS13115	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TVNIR_RS13125	COG0544	peptidyl-prolyl cis-trans isomerase activity
TVNIR_RS13135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TVNIR_RS13140	COG1923	regulation of RNA biosynthetic process
TVNIR_RS13145	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TVNIR_RS13150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TVNIR_RS13155	COG0860	N-Acetylmuramoyl-L-alanine amidase
TVNIR_RS13160	COG0802	atpase or kinase
TVNIR_RS13165	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TVNIR_RS13165	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TVNIR_RS13180	COG3118	belongs to the thioredoxin family
TVNIR_RS13195	COG0330	HflC and HflK could
TVNIR_RS13210	COG1763	Mo-molybdopterin cofactor biosynthetic process
TVNIR_RS13215	COG0303	'Molybdopterin
TVNIR_RS13240	COG1136	(ABC) transporter
TVNIR_RS13260	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TVNIR_RS13275	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
TVNIR_RS13290	COG0166	Belongs to the GPI family
TVNIR_RS13295	COG0297	glycogen (starch) synthase activity
TVNIR_RS13300	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
TVNIR_RS13305	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TVNIR_RS13310	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
TVNIR_RS13315	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TVNIR_RS13320	COG1428	Deoxynucleoside kinase
TVNIR_RS13325	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TVNIR_RS13330	COG0617	tRNA 3'-terminal CCA addition
TVNIR_RS13340	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
TVNIR_RS13345	COG0625	glutathione transferase activity
TVNIR_RS13350	COG2983	Belongs to the UPF0260 family
TVNIR_RS13370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TVNIR_RS13375	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
TVNIR_RS13380	COG0363	glucosamine-6-phosphate deaminase activity
TVNIR_RS13395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TVNIR_RS13415	COG1484	DNA-dependent DNA replication
TVNIR_RS13455	COG3041	Addiction module toxin RelE StbE family
TVNIR_RS13475	COG2226	methyltransferase
TVNIR_RS13510	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TVNIR_RS13515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TVNIR_RS13520	COG1993	acr, cog1993
TVNIR_RS13570	COG4974	Belongs to the 'phage' integrase family
TVNIR_RS13575	COG0517	IMP dehydrogenase activity
TVNIR_RS13585	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TVNIR_RS13600	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TVNIR_RS13600	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TVNIR_RS13605	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TVNIR_RS13610	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TVNIR_RS13625	COG3360	Dodecin
TVNIR_RS13640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TVNIR_RS13655	COG1215	transferase activity, transferring glycosyl groups
TVNIR_RS13665	COG2204	response regulator
TVNIR_RS13675	COG1458	PINc domain ribonuclease
TVNIR_RS13680	COG2267	carboxylic ester hydrolase activity
TVNIR_RS13680	COG2226	methyltransferase
TVNIR_RS13685	COG2433	Pfam Transposase IS66
TVNIR_RS13690	COG0129	dihydroxy-acid dehydratase activity
TVNIR_RS13700	COG1611	Belongs to the LOG family
TVNIR_RS13760	COG0123	including yeast histone deacetylase and acetoin utilization protein
TVNIR_RS13765	COG1042	CoA-binding domain protein
TVNIR_RS13765	COG0045	succinate-CoA ligase (ADP-forming) activity
TVNIR_RS13765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TVNIR_RS13775	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
TVNIR_RS13785	COG2361	Protein of unknown function DUF86
TVNIR_RS13805	COG1686	Belongs to the peptidase S11 family
TVNIR_RS13810	COG0398	Pfam SNARE associated Golgi protein
TVNIR_RS13815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TVNIR_RS13825	COG1674	ftsk spoiiie
TVNIR_RS13830	COG0492	ferredoxin-NADP+ reductase activity
TVNIR_RS13840	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
TVNIR_RS13850	COG4221	oxidoreductase activity
TVNIR_RS13855	COG2133	pyrroloquinoline quinone binding
TVNIR_RS13860	COG0587	DNA-directed DNA polymerase activity
TVNIR_RS13865	COG2210	Belongs to the sulfur carrier protein TusA family
TVNIR_RS13890	COG1192	Involved in chromosome partitioning
TVNIR_RS13905	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TVNIR_RS13920	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TVNIR_RS13930	COG0436	Aminotransferase
TVNIR_RS13950	COG1238	metal cluster binding
TVNIR_RS13955	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TVNIR_RS13960	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TVNIR_RS13975	COG1366	Belongs to the anti-sigma-factor antagonist family
TVNIR_RS13980	COG0585	pseudouridine synthase activity
TVNIR_RS13990	COG1199	ATP-dependent helicase activity
TVNIR_RS14000	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TVNIR_RS14015	COG0791	NLP P60 protein
TVNIR_RS14025	COG0521	Mo-molybdopterin cofactor biosynthetic process
TVNIR_RS14045	COG2166	iron-sulfur cluster assembly
TVNIR_RS14055	COG0583	DNA-binding transcription factor activity
TVNIR_RS14080	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
TVNIR_RS14085	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
TVNIR_RS14090	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
TVNIR_RS14115	COG4451	ribulose bisphosphate carboxylase, small
TVNIR_RS14120	COG1850	ribulose-bisphosphate carboxylase activity
TVNIR_RS14130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TVNIR_RS14170	COG0583	DNA-binding transcription factor activity
TVNIR_RS14175	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TVNIR_RS14200	COG4520	surface antigen
TVNIR_RS14205	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
TVNIR_RS14230	COG1999	signal sequence binding
TVNIR_RS14245	COG2391	methyltransferase activity
TVNIR_RS14250	COG0109	protoheme IX farnesyltransferase activity
TVNIR_RS14255	COG1612	heme a metabolic process
TVNIR_RS14300	COG2766	serine protein kinase
TVNIR_RS14305	COG2718	Belongs to the UPF0229 family
TVNIR_RS14310	COG2719	SpoVR family
TVNIR_RS14315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TVNIR_RS14345	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TVNIR_RS14365	COG0545	Peptidyl-prolyl cis-trans isomerase
TVNIR_RS14395	COG2951	lytic endotransglycosylase activity
TVNIR_RS14425	COG1917	Cupin 2, conserved barrel domain protein
TVNIR_RS14425	COG2207	Transcriptional regulator
TVNIR_RS14440	COG2249	NAD(P)H dehydrogenase (quinone) activity
TVNIR_RS14470	COG2234	aminopeptidase activity
TVNIR_RS14475	COG1960	acyl-CoA dehydrogenase activity
TVNIR_RS14480	COG2169	Transcriptional regulator
TVNIR_RS14490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TVNIR_RS14490	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TVNIR_RS14495	COG3588	fructose-bisphosphate aldolase
TVNIR_RS14505	COG0129	dihydroxy-acid dehydratase activity
TVNIR_RS14550	COG0822	iron-sulfur transferase activity
TVNIR_RS14560	COG0519	Catalyzes the synthesis of GMP from XMP
TVNIR_RS14560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TVNIR_RS14570	COG1570	exodeoxyribonuclease VII activity
TVNIR_RS14575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TVNIR_RS14580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TVNIR_RS14585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TVNIR_RS14610	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TVNIR_RS14625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TVNIR_RS14640	COG2308	Evidence 4 Homologs of previously reported genes of
TVNIR_RS14650	COG1185	polyribonucleotide nucleotidyltransferase activity
TVNIR_RS14655	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TVNIR_RS14660	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TVNIR_RS14665	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TVNIR_RS14670	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TVNIR_RS14675	COG2251	uridine kinase activity
TVNIR_RS14675	COG0195	Participates in both transcription termination and antitermination
TVNIR_RS14690	COG1007	ATP synthesis coupled electron transport
TVNIR_RS14705	COG0713	ATP synthesis coupled electron transport
TVNIR_RS14715	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TVNIR_RS14720	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TVNIR_RS14725	COG1034	ATP synthesis coupled electron transport
TVNIR_RS14740	COG0649	NAD binding
TVNIR_RS14745	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TVNIR_RS14750	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TVNIR_RS14755	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TVNIR_RS14770	COG0149	triose-phosphate isomerase activity
TVNIR_RS14775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TVNIR_RS14780	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TVNIR_RS14790	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
TVNIR_RS14795	COG1534	Rna-binding protein
TVNIR_RS14800	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TVNIR_RS14810	COG0505	Belongs to the CarA family
TVNIR_RS14820	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
TVNIR_RS14830	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TVNIR_RS14845	COG0688	phosphatidylethanolamine metabolic process
TVNIR_RS14850	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
TVNIR_RS14855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TVNIR_RS14860	COG1509	lysine 2,3-aminomutase activity
TVNIR_RS14870	COG2200	EAL domain
TVNIR_RS14875	COG0484	heat shock protein binding
TVNIR_RS14880	COG0443	Heat shock 70 kDa protein
TVNIR_RS14885	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TVNIR_RS14890	COG1420	regulation of RNA biosynthetic process
TVNIR_RS14895	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TVNIR_RS14900	COG0497	DNA recombination
TVNIR_RS14905	COG0735	belongs to the Fur family
TVNIR_RS14910	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TVNIR_RS14915	COG2914	Belongs to the UPF0125 (RnfH) family
TVNIR_RS14920	COG2867	negative regulation of translational initiation
TVNIR_RS14925	COG0733	neurotransmitter:sodium symporter activity
TVNIR_RS14930	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TVNIR_RS14935	COG1858	cytochrome C peroxidase
TVNIR_RS14950	COG0488	(ABC) transporter
TVNIR_RS14965	COG0523	cobalamin synthesis protein
TVNIR_RS14985	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TVNIR_RS15010	COG2135	peptidase activity
TVNIR_RS15040	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TVNIR_RS15050	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TVNIR_RS15055	COG2833	Protein of unknown function (DUF455)
TVNIR_RS15080	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TVNIR_RS15085	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TVNIR_RS15105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TVNIR_RS15110	COG0501	Belongs to the peptidase M48B family
TVNIR_RS15120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TVNIR_RS15150	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TVNIR_RS15160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TVNIR_RS15160	COG0519	Catalyzes the synthesis of GMP from XMP
TVNIR_RS15165	COG0525	valine-tRNA ligase activity
TVNIR_RS15180	COG2027	D-alanyl-D-alanine carboxypeptidase
TVNIR_RS15195	COG5265	(ABC) transporter
TVNIR_RS15210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
TVNIR_RS15225	COG0456	acetyltransferase
TVNIR_RS15230	COG1573	uracil-dna glycosylase
TVNIR_RS15235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TVNIR_RS15240	COG1183	phosphatidylcholine synthase activity
TVNIR_RS15250	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TVNIR_RS15260	COG0028	Belongs to the TPP enzyme family
TVNIR_RS15280	COG0095	Lipoate-protein ligase
TVNIR_RS15310	COG4771	TonB-dependent receptor
TVNIR_RS15315	COG0509	glycine decarboxylation via glycine cleavage system
TVNIR_RS15325	COG0509	glycine decarboxylation via glycine cleavage system
TVNIR_RS15330	COG2048	Heterodisulfide reductase, subunit B
TVNIR_RS15360	COG0425	Belongs to the sulfur carrier protein TusA family
TVNIR_RS15365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TVNIR_RS15375	COG4783	chaperone-mediated protein folding
TVNIR_RS15385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TVNIR_RS15390	COG0305	Participates in initiation and elongation during chromosome replication
TVNIR_RS15395	COG0359	binds to the 23S rRNA
TVNIR_RS15405	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TVNIR_RS15410	COG0360	Binds together with S18 to 16S ribosomal RNA
TVNIR_RS15415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TVNIR_RS15420	COG0557	exoribonuclease II activity
TVNIR_RS15430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TVNIR_RS15435	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
TVNIR_RS15445	COG0330	HflC and HflK could
TVNIR_RS15450	COG0330	HflC and HflK could
TVNIR_RS15460	COG0435	Glutathione S-transferase
TVNIR_RS15490	COG3485	protocatechuate 3,4-dioxygenase
TVNIR_RS15520	COG3267	Type II secretory pathway component ExeA
TVNIR_RS15520	COG3409	Peptidoglycan-binding domain 1 protein
TVNIR_RS15545	COG1051	belongs to the nudix hydrolase family
TVNIR_RS15550	COG0210	DNA helicase
TVNIR_RS15640	COG3550	peptidyl-serine autophosphorylation
TVNIR_RS15660	COG3609	addiction module antidote protein, CC2985 family
TVNIR_RS15695	COG3311	Transcriptional regulator
TVNIR_RS15700	COG3012	SEC-C Motif Domain Protein
TVNIR_RS15710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TVNIR_RS15755	COG1082	Xylose isomerase domain protein TIM barrel
TVNIR_RS15775	COG0811	peptide transport
TVNIR_RS15815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TVNIR_RS15820	COG0604	alcohol dehydrogenase
TVNIR_RS15840	COG3321	synthase
TVNIR_RS15840	COG0604	alcohol dehydrogenase
TVNIR_RS15870	COG0446	pyridine nucleotide-disulphide oxidoreductase
TVNIR_RS15900	COG4716	Myosin-crossreactive antigen
TVNIR_RS15910	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
TVNIR_RS15915	COG0602	queuosine metabolic process
TVNIR_RS15930	COG0823	Involved in the tonB-independent uptake of proteins
TVNIR_RS15950	COG0824	Thioesterase
TVNIR_RS15955	COG2255	four-way junction helicase activity
TVNIR_RS15960	COG0632	four-way junction helicase activity
TVNIR_RS15965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TVNIR_RS15970	COG0217	transcriptional regulatory protein
TVNIR_RS15980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TVNIR_RS16000	COG0300	oxidoreductase activity
TVNIR_RS16005	COG2715	membrane protein required for spore maturation
TVNIR_RS16010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TVNIR_RS16035	COG0442	prolyl-tRNA aminoacylation
TVNIR_RS16040	COG1254	Belongs to the acylphosphatase family
TVNIR_RS16045	COG1393	Belongs to the ArsC family
TVNIR_RS16060	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TVNIR_RS16065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TVNIR_RS16070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TVNIR_RS16075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TVNIR_RS16085	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TVNIR_RS16090	COG0312	modulator of DNA gyrase
TVNIR_RS16100	COG0312	modulator of DNA gyrase
TVNIR_RS16105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TVNIR_RS16115	COG1530	ribonuclease E activity
TVNIR_RS16150	COG0616	signal peptide processing
TVNIR_RS16155	COG0326	Molecular chaperone. Has ATPase activity
TVNIR_RS16160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
TVNIR_RS16165	COG2010	Cytochrome c
TVNIR_RS16180	COG0335	large ribosomal subunit rRNA binding
TVNIR_RS16185	COG0336	Belongs to the RNA methyltransferase TrmD family
TVNIR_RS16190	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TVNIR_RS16195	COG0228	four-way junction DNA binding
TVNIR_RS16200	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TVNIR_RS16205	COG4137	Cytochrome C assembly protein
TVNIR_RS16210	COG4536	flavin adenine dinucleotide binding
TVNIR_RS16235	COG1592	Rubrerythrin
TVNIR_RS16240	COG1722	exodeoxyribonuclease VII activity
TVNIR_RS16245	COG0142	geranyltranstransferase activity
TVNIR_RS16250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TVNIR_RS16255	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
TVNIR_RS16260	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TVNIR_RS16270	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TVNIR_RS16275	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
TVNIR_RS16280	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TVNIR_RS16310	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TVNIR_RS16315	COG0739	heme binding
TVNIR_RS16325	COG0316	Belongs to the HesB IscA family
TVNIR_RS16330	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TVNIR_RS16345	COG0494	nUDIX hydrolase
TVNIR_RS16355	COG0352	thiamine-phosphate diphosphorylase activity
TVNIR_RS16355	COG0351	phosphomethylpyrimidine kinase
TVNIR_RS16360	COG0352	thiamine-phosphate diphosphorylase activity
TVNIR_RS16365	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TVNIR_RS16370	COG0730	response to heat
TVNIR_RS16375	COG0308	aminopeptidase N
TVNIR_RS16380	COG0084	hydrolase, TatD family'
TVNIR_RS16385	COG0271	Belongs to the BolA IbaG family
TVNIR_RS16415	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TVNIR_RS16420	COG1470	cell adhesion involved in biofilm formation
TVNIR_RS16420	COG1388	LysM domain
TVNIR_RS16460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TVNIR_RS16475	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TVNIR_RS16480	COG0232	Belongs to the dGTPase family. Type 2 subfamily
TVNIR_RS16490	COG1120	ATPase activity
TVNIR_RS16495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TVNIR_RS16500	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TVNIR_RS16505	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TVNIR_RS16550	COG4206	TonB-dependent receptor
TVNIR_RS16555	COG0358	DNA primase activity
TVNIR_RS16645	COG3344	reverse transcriptase
TVNIR_RS16660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
TVNIR_RS16665	COG4941	Belongs to the sigma-70 factor family
TVNIR_RS16675	COG3795	YCII-related domain
TVNIR_RS16790	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TVNIR_RS16805	COG0463	Glycosyl transferase, family 2
TVNIR_RS16820	COG1546	Belongs to the CinA family
TVNIR_RS16820	COG1058	Belongs to the CinA family
TVNIR_RS16825	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
TVNIR_RS16840	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
TVNIR_RS16850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TVNIR_RS16855	COG0018	arginyl-trna synthetase
TVNIR_RS16865	COG1643	Atp-dependent helicase
TVNIR_RS16890	COG0735	belongs to the Fur family
TVNIR_RS16900	COG4772	TonB-dependent receptor
TVNIR_RS16915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TVNIR_RS16945	COG5002	protein histidine kinase activity
TVNIR_RS16945	COG5001	Diguanylate cyclase
TVNIR_RS16950	COG0235	Class ii aldolase
TVNIR_RS16955	COG0121	glutamine amidotransferase
TVNIR_RS16965	COG1067	ATP-dependent peptidase activity
TVNIR_RS16970	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TVNIR_RS16995	COG1484	DNA-dependent DNA replication
TVNIR_RS17015	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
TVNIR_RS17035	COG0315	cyclic pyranopterin monophosphate synthase activity
TVNIR_RS17040	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
TVNIR_RS17050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TVNIR_RS17060	COG0071	Belongs to the small heat shock protein (HSP20) family
TVNIR_RS17065	COG1561	YicC-like family, N-terminal region
TVNIR_RS17070	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TVNIR_RS17075	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TVNIR_RS17080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TVNIR_RS17110	COG1047	Peptidyl-prolyl cis-trans
TVNIR_RS17135	COG2046	Belongs to the sulfate adenylyltransferase family
TVNIR_RS17150	COG0243	molybdopterin cofactor binding
TVNIR_RS17155	COG0437	4 iron, 4 sulfur cluster binding
TVNIR_RS17160	COG3302	dmso reductase anchor subunit
TVNIR_RS17170	COG0563	adenylate kinase activity
TVNIR_RS17175	COG0205	6-phosphofructokinase activity
TVNIR_RS17180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TVNIR_RS17185	COG1012	belongs to the aldehyde dehydrogenase family
TVNIR_RS17195	COG0617	tRNA 3'-terminal CCA addition
TVNIR_RS17200	COG1309	transcriptional regulator
TVNIR_RS17205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TVNIR_RS17210	COG1538	Outer membrane efflux protein
TVNIR_RS17220	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
TVNIR_RS17230	COG0488	(ABC) transporter
TVNIR_RS17235	COG1444	tRNA N-acetyltransferase activity
TVNIR_RS17245	COG0174	glutamine synthetase
TVNIR_RS17265	COG0752	glycyl-tRNA synthetase alpha subunit
TVNIR_RS17270	COG0751	glycine-tRNA ligase activity
TVNIR_RS17280	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TVNIR_RS17285	COG0084	hydrolase, TatD family'
TVNIR_RS17300	COG0667	Aldo Keto reductase
TVNIR_RS17315	COG3954	Phosphoribulokinase
TVNIR_RS17320	COG3273	potassium ion transport
TVNIR_RS17320	COG0471	metal ion transport
TVNIR_RS17325	COG0589	response to stress
TVNIR_RS17330	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TVNIR_RS17335	COG2022	thiamine diphosphate biosynthetic process
TVNIR_RS17410	COG1741	Belongs to the pirin family
TVNIR_RS17425	COG2226	methyltransferase
TVNIR_RS17445	COG3609	addiction module antidote protein, CC2985 family
TVNIR_RS17455	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TVNIR_RS17460	COG1574	metal-dependent hydrolase with the TIM-barrel fold
TVNIR_RS17475	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
TVNIR_RS17515	COG5001	Diguanylate cyclase
TVNIR_RS17535	COG0194	GDP metabolic process
TVNIR_RS17540	COG1758	RNA polymerase activity
TVNIR_RS17545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TVNIR_RS17565	COG0037	tRNA processing
TVNIR_RS17570	COG0445	tRNA wobble uridine modification
TVNIR_RS17575	COG0357	Ribosomal RNA small subunit methyltransferase G
TVNIR_RS17580	COG1192	Involved in chromosome partitioning
TVNIR_RS17585	COG1475	DNA binding
TVNIR_RS17595	COG0356	it plays a direct role in the translocation of protons across the membrane
TVNIR_RS17605	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TVNIR_RS17610	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TVNIR_RS17615	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
TVNIR_RS17620	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
TVNIR_RS17625	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
TVNIR_RS17630	COG0355	proton-transporting ATP synthase activity, rotational mechanism
TVNIR_RS17635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TVNIR_RS17640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TVNIR_RS17650	COG1628	Protein of unknown function DUF99
TVNIR_RS17665	COG0561	phosphatase activity
TVNIR_RS17665	COG3100	YcgL domain-containing protein
TVNIR_RS17675	COG0793	Belongs to the peptidase S41A family
TVNIR_RS17680	COG4942	peptidase
TVNIR_RS17690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TVNIR_RS17705	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TVNIR_RS17710	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
TVNIR_RS17720	COG3852	Histidine kinase
TVNIR_RS17735	COG1611	Belongs to the LOG family
TVNIR_RS17750	COG1999	signal sequence binding
TVNIR_RS17760	COG0218	Necessary for normal cell division and for the maintenance of normal septation
TVNIR_RS17785	COG0367	asparagine synthase
TVNIR_RS17790	COG0540	Belongs to the ATCase OTCase family
TVNIR_RS17795	COG1335	isochorismatase
TVNIR_RS17805	COG1846	Transcriptional regulator
TVNIR_RS17815	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
TVNIR_RS17830	COG0708	Exodeoxyribonuclease III
TVNIR_RS17835	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TVNIR_RS17845	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TVNIR_RS17865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TVNIR_RS17870	COG0513	Belongs to the DEAD box helicase family
TVNIR_RS17875	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
TVNIR_RS17880	COG0205	6-phosphofructokinase activity
TVNIR_RS17895	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TVNIR_RS17900	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
TVNIR_RS17905	COG0405	Gamma-glutamyltransferase
TVNIR_RS17935	COG0508	dehydrogenase complex catalyzes the overall conversion of
TVNIR_RS17945	COG0210	DNA helicase
TVNIR_RS17970	COG0446	pyridine nucleotide-disulphide oxidoreductase
TVNIR_RS17995	COG1490	D-aminoacyl-tRNA deacylase activity
TVNIR_RS18000	COG1394	ATPase activity, coupled to movement of substances
TVNIR_RS18005	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TVNIR_RS18010	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TVNIR_RS18015	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
TVNIR_RS18050	COG0706	membrane insertase activity
TVNIR_RS18060	COG0594	ribonuclease P activity
TVNIR_RS18065	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TVNIR_RS18070	COG0592	DNA-directed DNA polymerase activity
TVNIR_RS18075	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TVNIR_RS18085	COG0187	DNA topoisomerase II activity
TVNIR_RS18090	COG1704	LemA family
TVNIR_RS18100	COG0339	signal peptide processing
TVNIR_RS18115	COG2862	Uncharacterized protein family, UPF0114
TVNIR_RS18120	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TVNIR_RS18135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TVNIR_RS18135	COG0543	2 iron, 2 sulfur cluster binding
TVNIR_RS18145	COG0181	hydroxymethylbilane synthase activity
TVNIR_RS18150	COG0165	Argininosuccinate lyase
TVNIR_RS18205	COG1459	type II secretion system
TVNIR_RS18220	COG3031	protein transport across the cell outer membrane
TVNIR_RS18225	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
TVNIR_RS18230	COG2197	response regulator
TVNIR_RS18240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TVNIR_RS18245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family