locus-tag	class	description
Ga0080559_RS00045	COG4397	Mu-like prophage major head subunit gpT
Ga0080559_RS00100	COG0640	Transcriptional regulator
Ga0080559_RS00175	COG2801	Transposase and inactivated derivatives
Ga0080559_RS00325	COG4206	TonB-dependent receptor
Ga0080559_RS00340	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Ga0080559_RS00350	COG0084	hydrolase, TatD family'
Ga0080559_RS00370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Ga0080559_RS00380	COG0477	Major facilitator Superfamily
Ga0080559_RS00385	COG2917	probably involved in intracellular septation
Ga0080559_RS00390	COG1285	pathogenesis
Ga0080559_RS00395	COG0552	protein localization to endoplasmic reticulum
Ga0080559_RS00400	COG0741	lytic transglycosylase activity
Ga0080559_RS00415	COG1570	exodeoxyribonuclease VII activity
Ga0080559_RS00420	COG0151	Belongs to the GarS family
Ga0080559_RS00430	COG0783	Belongs to the Dps family
Ga0080559_RS00440	COG2239	Acts as a magnesium transporter
Ga0080559_RS00445	COG0402	S-adenosylhomocysteine deaminase activity
Ga0080559_RS00450	COG0702	epimerase
Ga0080559_RS00470	COG0483	inositol monophosphate 1-phosphatase activity
Ga0080559_RS00475	COG1396	sequence-specific DNA binding
Ga0080559_RS00485	COG0583	DNA-binding transcription factor activity
Ga0080559_RS00495	COG0670	Belongs to the BI1 family
Ga0080559_RS00500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Ga0080559_RS00505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Ga0080559_RS00505	COG0512	Glutamine amidotransferase of anthranilate synthase
Ga0080559_RS00510	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Ga0080559_RS00520	COG2267	carboxylic ester hydrolase activity
Ga0080559_RS00545	COG0217	transcriptional regulatory protein
Ga0080559_RS00560	COG0519	Catalyzes the synthesis of GMP from XMP
Ga0080559_RS00560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Ga0080559_RS00580	COG3273	potassium ion transport
Ga0080559_RS00580	COG0471	metal ion transport
Ga0080559_RS00585	COG1692	metallophosphoesterase
Ga0080559_RS00605	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Ga0080559_RS00615	COG0840	transmembrane signaling receptor activity
Ga0080559_RS00625	COG0330	HflC and HflK could
Ga0080559_RS00630	COG0330	HflC and HflK could
Ga0080559_RS00640	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Ga0080559_RS00645	COG1760	l-serine dehydratase
Ga0080559_RS00650	COG0456	acetyltransferase
Ga0080559_RS00660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Ga0080559_RS00665	COG0508	dehydrogenase complex catalyzes the overall conversion of
Ga0080559_RS00665	COG0022	dehydrogenase e1 component
Ga0080559_RS00675	COG0508	dehydrogenase complex catalyzes the overall conversion of
Ga0080559_RS00680	COG2814	Major facilitator Superfamily
Ga0080559_RS00685	COG1045	serine acetyltransferase
Ga0080559_RS00765	COG4695	Portal protein
Ga0080559_RS00785	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Ga0080559_RS00825	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Ga0080559_RS00835	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Ga0080559_RS00840	COG5265	(ABC) transporter
Ga0080559_RS00850	COG1611	Belongs to the LOG family
Ga0080559_RS00855	COG0741	lytic transglycosylase activity
Ga0080559_RS00860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Ga0080559_RS00865	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Ga0080559_RS00875	COG0612	Peptidase, M16
Ga0080559_RS00880	COG0612	Peptidase, M16
Ga0080559_RS00890	COG0138	bifunctional purine biosynthesis protein purh
Ga0080559_RS00910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Ga0080559_RS00915	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Ga0080559_RS00920	COG3698	Phosphodiester glycosidase
Ga0080559_RS00925	COG0312	modulator of DNA gyrase
Ga0080559_RS00930	COG0483	inositol monophosphate 1-phosphatase activity
Ga0080559_RS00940	COG1519	Transferase
Ga0080559_RS00945	COG1663	tetraacyldisaccharide 4'-kinase activity
Ga0080559_RS00960	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Ga0080559_RS00970	COG0135	phosphoribosylanthranilate isomerase activity
Ga0080559_RS00980	COG0776	regulation of translation
Ga0080559_RS00985	COG0539	negative regulation of cytoplasmic translation
Ga0080559_RS00990	COG0667	Aldo Keto reductase
Ga0080559_RS00995	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Ga0080559_RS01005	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Ga0080559_RS01010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Ga0080559_RS01015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Ga0080559_RS01020	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Ga0080559_RS01025	COG1253	flavin adenine dinucleotide binding
Ga0080559_RS01030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Ga0080559_RS01035	COG1702	phosphate starvation-inducible protein PhoH
Ga0080559_RS01050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Ga0080559_RS01060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Ga0080559_RS01070	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Ga0080559_RS01080	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Ga0080559_RS01085	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Ga0080559_RS01095	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Ga0080559_RS01120	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Ga0080559_RS01120	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Ga0080559_RS01140	COG4770	biotin carboxylase activity
Ga0080559_RS01165	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Ga0080559_RS01170	COG2814	Major facilitator Superfamily
Ga0080559_RS01175	COG1396	sequence-specific DNA binding
Ga0080559_RS01175	COG3800	Transcriptional regulator
Ga0080559_RS01180	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Ga0080559_RS01185	COG0154	amidase activity
Ga0080559_RS01200	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Ga0080559_RS01215	COG2873	o-acetylhomoserine
Ga0080559_RS01230	COG0210	DNA helicase
Ga0080559_RS01240	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Ga0080559_RS01315	COG2010	Cytochrome c
Ga0080559_RS01375	COG0398	Pfam SNARE associated Golgi protein
Ga0080559_RS01405	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080559_RS01410	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080559_RS01440	COG0583	DNA-binding transcription factor activity
Ga0080559_RS01445	COG0277	FAD linked oxidase domain protein
Ga0080559_RS01465	COG0673	inositol 2-dehydrogenase activity
Ga0080559_RS01470	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS01485	COG0811	peptide transport
Ga0080559_RS01505	COG0435	Glutathione S-transferase
Ga0080559_RS01510	COG3384	dioxygenase
Ga0080559_RS01515	COG2259	Doxx family
Ga0080559_RS01520	COG0583	DNA-binding transcription factor activity
Ga0080559_RS01530	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Ga0080559_RS01570	COG4160	amino acid transport
Ga0080559_RS01580	COG0174	glutamine synthetase
Ga0080559_RS01585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Ga0080559_RS01585	COG0519	Catalyzes the synthesis of GMP from XMP
Ga0080559_RS01590	COG0174	glutamine synthetase
Ga0080559_RS01595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080559_RS01600	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Ga0080559_RS01620	COG0564	pseudouridine synthase activity
Ga0080559_RS01630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Ga0080559_RS01645	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Ga0080559_RS01650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Ga0080559_RS01665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ga0080559_RS01715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Ga0080559_RS01720	COG1121	(ABC) transporter
Ga0080559_RS01725	COG0735	belongs to the Fur family
Ga0080559_RS01735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Ga0080559_RS01740	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Ga0080559_RS01745	COG1984	allophanate hydrolase subunit 2
Ga0080559_RS01750	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Ga0080559_RS01755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Ga0080559_RS01760	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Ga0080559_RS01765	COG1530	ribonuclease E activity
Ga0080559_RS01780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Ga0080559_RS01780	COG3153	acetyltransferase
Ga0080559_RS01785	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Ga0080559_RS01805	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Ga0080559_RS01820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Ga0080559_RS01840	COG0028	Belongs to the TPP enzyme family
Ga0080559_RS01850	COG0745	RESPONSE REGULATOR receiver
Ga0080559_RS01860	COG0835	chemotaxis
Ga0080559_RS01865	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Ga0080559_RS01870	COG0745	RESPONSE REGULATOR receiver
Ga0080559_RS01880	COG2201	protein-glutamate methylesterase activity
Ga0080559_RS01885	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Ga0080559_RS01905	COG2308	Evidence 4 Homologs of previously reported genes of
Ga0080559_RS01915	COG0559	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS01945	COG0395	ABC-type sugar transport system, permease component
Ga0080559_RS01950	COG3408	Glycogen debranching enzyme
Ga0080559_RS01950	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
Ga0080559_RS01965	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Ga0080559_RS01975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Ga0080559_RS01980	COG1070	Carbohydrate kinase
Ga0080559_RS01990	COG1175	transmembrane transport
Ga0080559_RS01995	COG0395	ABC-type sugar transport system, permease component
Ga0080559_RS02000	COG3842	ATPase activity
Ga0080559_RS02010	COG2390	Transcriptional regulator
Ga0080559_RS02020	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
Ga0080559_RS02045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Ga0080559_RS02330	COG1522	sequence-specific DNA binding
Ga0080559_RS02350	COG0483	inositol monophosphate 1-phosphatase activity
Ga0080559_RS02390	COG0346	lactoylglutathione lyase activity
Ga0080559_RS02395	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
Ga0080559_RS02400	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Ga0080559_RS02410	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Ga0080559_RS02425	COG0804	urea catabolic process
Ga0080559_RS02445	COG0832	Belongs to the urease beta subunit family
Ga0080559_RS02450	COG0831	urea catabolic process
Ga0080559_RS02455	COG0829	nickel cation binding
Ga0080559_RS02460	COG1720	tRNA m6t6A37 methyltransferase activity
Ga0080559_RS02465	COG3734	2-keto-3-deoxy-galactonokinase
Ga0080559_RS02485	COG2307	Protein conserved in bacteria
Ga0080559_RS02485	COG2308	Evidence 4 Homologs of previously reported genes of
Ga0080559_RS02510	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080559_RS02555	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Ga0080559_RS02565	COG3750	Belongs to the UPF0335 family
Ga0080559_RS02575	COG1024	Enoyl-CoA hydratase
Ga0080559_RS02575	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080559_RS02595	COG2391	methyltransferase activity
Ga0080559_RS02625	COG0745	RESPONSE REGULATOR receiver
Ga0080559_RS02655	COG0410	ABC transporter
Ga0080559_RS02660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ga0080559_RS02665	COG0511	ligase activity, forming carbon-carbon bonds
Ga0080559_RS02670	COG0439	Biotin carboxylase
Ga0080559_RS02675	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Ga0080559_RS02695	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Ga0080559_RS02700	COG0740	serine-type endopeptidase activity
Ga0080559_RS02725	COG0737	Belongs to the 5'-nucleotidase family
Ga0080559_RS02730	COG3258	Cytochrome c
Ga0080559_RS02755	COG0785	Cytochrome C biogenesis protein
Ga0080559_RS02770	COG2391	methyltransferase activity
Ga0080559_RS02800	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Ga0080559_RS02845	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Ga0080559_RS02850	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Ga0080559_RS02855	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Ga0080559_RS02860	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
Ga0080559_RS02865	COG0295	cytidine deaminase activity
Ga0080559_RS02875	COG1194	a g-specific adenine glycosylase
Ga0080559_RS02885	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Ga0080559_RS02890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Ga0080559_RS02895	COG3346	SURF1 family
Ga0080559_RS02905	COG0612	Peptidase, M16
Ga0080559_RS02925	COG0741	lytic transglycosylase activity
Ga0080559_RS02950	COG4964	Belongs to the GSP D family
Ga0080559_RS02960	COG2894	cell division
Ga0080559_RS03025	COG3842	ATPase activity
Ga0080559_RS03030	COG0006	proline dipeptidase activity
Ga0080559_RS03055	COG0745	RESPONSE REGULATOR receiver
Ga0080559_RS03085	COG0768	penicillin binding
Ga0080559_RS03090	COG0772	Belongs to the SEDS family
Ga0080559_RS03095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Ga0080559_RS03125	COG0604	alcohol dehydrogenase
Ga0080559_RS03130	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Ga0080559_RS03130	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Ga0080559_RS03140	COG0813	purine-nucleoside phosphorylase activity
Ga0080559_RS03145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Ga0080559_RS03240	COG2030	dehydratase
Ga0080559_RS03265	COG0039	L-malate dehydrogenase activity
Ga0080559_RS03275	COG0045	succinate-CoA ligase (ADP-forming) activity
Ga0080559_RS03285	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Ga0080559_RS03295	COG0508	dehydrogenase complex catalyzes the overall conversion of
Ga0080559_RS03345	COG2884	Cell division ATP-binding protein ftsE
Ga0080559_RS03355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080559_RS03360	COG1116	anion transmembrane transporter activity
Ga0080559_RS03370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Ga0080559_RS03385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Ga0080559_RS03390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Ga0080559_RS03395	COG1846	Transcriptional regulator
Ga0080559_RS03400	COG0745	RESPONSE REGULATOR receiver
Ga0080559_RS03405	COG0123	including yeast histone deacetylase and acetoin utilization protein
Ga0080559_RS03410	COG1722	exodeoxyribonuclease VII activity
Ga0080559_RS03415	COG0142	geranyltranstransferase activity
Ga0080559_RS03420	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Ga0080559_RS03440	COG1132	(ABC) transporter
Ga0080559_RS03445	COG0667	Aldo Keto reductase
Ga0080559_RS03450	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Ga0080559_RS03455	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Ga0080559_RS03470	COG1047	Peptidyl-prolyl cis-trans
Ga0080559_RS03475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Ga0080559_RS03490	COG0640	Transcriptional regulator
Ga0080559_RS03495	COG0318	PFAM AMP-dependent synthetase and ligase
Ga0080559_RS03515	COG0737	Belongs to the 5'-nucleotidase family
Ga0080559_RS03535	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
Ga0080559_RS03615	COG0730	response to heat
Ga0080559_RS03640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Ga0080559_RS03640	COG3453	Protein conserved in bacteria
Ga0080559_RS03645	COG0765	amino acid transport
Ga0080559_RS03650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Ga0080559_RS03655	COG0765	amino acid transport
Ga0080559_RS03660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Ga0080559_RS03660	COG0072	phenylalanine-tRNA ligase activity
Ga0080559_RS03670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Ga0080559_RS03690	COG0028	Belongs to the TPP enzyme family
Ga0080559_RS03705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Ga0080559_RS03715	COG0681	Belongs to the peptidase S26 family
Ga0080559_RS03720	COG0571	ribonuclease III activity
Ga0080559_RS03735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Ga0080559_RS03750	COG1381	Involved in DNA repair and RecF pathway recombination
Ga0080559_RS03755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Ga0080559_RS03765	COG0314	molybdopterin synthase activity
Ga0080559_RS03785	COG0004	ammonium transporteR
Ga0080559_RS03790	COG0347	Belongs to the P(II) protein family
Ga0080559_RS03800	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080559_RS03805	COG0799	negative regulation of ribosome biogenesis
Ga0080559_RS03810	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Ga0080559_RS03815	COG1968	undecaprenyl-diphosphatase activity
Ga0080559_RS03840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Ga0080559_RS03880	COG0697	spore germination
Ga0080559_RS03885	COG1283	sodium-dependent phosphate transmembrane transporter activity
Ga0080559_RS03890	COG0473	3-isopropylmalate dehydrogenase activity
Ga0080559_RS03905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Ga0080559_RS03915	COG0066	3-isopropylmalate dehydratase activity
Ga0080559_RS03930	COG3264	Mechanosensitive ion channel
Ga0080559_RS03930	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Ga0080559_RS03935	COG0183	Belongs to the thiolase family
Ga0080559_RS03940	COG4953	penicillin-binding protein 1C
Ga0080559_RS03955	COG2205	protein histidine kinase activity
Ga0080559_RS03955	COG0784	Response regulator, receiver
Ga0080559_RS03955	COG5002	protein histidine kinase activity
Ga0080559_RS03960	COG3022	response to hydroperoxide
Ga0080559_RS03965	COG0514	ATP-dependent DNA helicase (RecQ)
Ga0080559_RS03985	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
Ga0080559_RS03995	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Ga0080559_RS04015	COG3830	Belongs to the UPF0237 family
Ga0080559_RS04015	COG0560	Phosphoserine phosphatase
Ga0080559_RS04030	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
Ga0080559_RS04040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080559_RS04045	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Ga0080559_RS04050	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Ga0080559_RS04055	COG0747	negative chemotaxis
Ga0080559_RS04060	COG1678	Uncharacterized ACR, COG1678
Ga0080559_RS04080	COG0521	Mo-molybdopterin cofactor biosynthetic process
Ga0080559_RS04090	COG1573	uracil-dna glycosylase
Ga0080559_RS04095	COG0540	Belongs to the ATCase OTCase family
Ga0080559_RS04115	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Ga0080559_RS04135	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Ga0080559_RS04140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Ga0080559_RS04145	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Ga0080559_RS04150	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Ga0080559_RS04155	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Ga0080559_RS04165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Ga0080559_RS04195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Ga0080559_RS04200	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Ga0080559_RS04205	COG2080	2 iron, 2 sulfur cluster binding
Ga0080559_RS04210	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Ga0080559_RS04210	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Ga0080559_RS04225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Ga0080559_RS04235	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Ga0080559_RS04245	COG1238	metal cluster binding
Ga0080559_RS04255	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Ga0080559_RS04275	COG0328	RNA-DNA hybrid ribonuclease activity
Ga0080559_RS04285	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
Ga0080559_RS04290	COG0242	peptide deformylase activity
Ga0080559_RS04295	COG0242	peptide deformylase activity
Ga0080559_RS04300	COG0242	peptide deformylase activity
Ga0080559_RS04310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Ga0080559_RS04325	COG2951	lytic endotransglycosylase activity
Ga0080559_RS04345	COG0180	Tryptophanyl-tRNA synthetase
Ga0080559_RS04355	COG0697	spore germination
Ga0080559_RS04360	COG1131	(ABC) transporter
Ga0080559_RS04365	COG0842	Transport permease protein
Ga0080559_RS04370	COG2391	methyltransferase activity
Ga0080559_RS04375	COG0662	Cupin 2, conserved barrel domain protein
Ga0080559_RS04385	COG2264	protein methyltransferase activity
Ga0080559_RS04400	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Ga0080559_RS04405	COG0632	four-way junction helicase activity
Ga0080559_RS04410	COG2255	four-way junction helicase activity
Ga0080559_RS04415	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Ga0080559_RS04420	COG0181	hydroxymethylbilane synthase activity
Ga0080559_RS04440	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Ga0080559_RS04445	COG1686	Belongs to the peptidase S11 family
Ga0080559_RS04455	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Ga0080559_RS04470	COG0408	coproporphyrinogen oxidase activity
Ga0080559_RS04510	COG0435	Glutathione S-transferase
Ga0080559_RS04520	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Ga0080559_RS04525	COG1079	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS04530	COG4603	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS04535	COG3845	ABC transporter
Ga0080559_RS04540	COG1744	ABC transporter substrate-binding protein PnrA-like
Ga0080559_RS04550	COG1214	PFAM Peptidase M22, glycoprotease
Ga0080559_RS04555	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
Ga0080559_RS04575	COG0322	excinuclease ABC activity
Ga0080559_RS04580	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS04590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Ga0080559_RS04590	COG0616	signal peptide processing
Ga0080559_RS04600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Ga0080559_RS04615	COG1192	Involved in chromosome partitioning
Ga0080559_RS04645	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Ga0080559_RS04665	COG0488	(ABC) transporter
Ga0080559_RS04670	COG1278	Cold shock
Ga0080559_RS04680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Ga0080559_RS04690	COG0725	ABC transporter, periplasmic molybdate-binding protein
Ga0080559_RS04695	COG4149	molybdate abc transporter
Ga0080559_RS04700	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Ga0080559_RS04720	COG0463	Glycosyl transferase, family 2
Ga0080559_RS04725	COG4638	Rieske (2fe-2S)
Ga0080559_RS04735	COG1376	ErfK ybiS ycfS ynhG family protein
Ga0080559_RS04745	COG1435	thymidine kinase activity
Ga0080559_RS04750	COG1183	phosphatidylcholine synthase activity
Ga0080559_RS04755	COG2808	Putative FMN-binding domain
Ga0080559_RS04760	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Ga0080559_RS04765	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Ga0080559_RS04775	COG2198	Histidine kinase
Ga0080559_RS04775	COG0784	Response regulator, receiver
Ga0080559_RS04775	COG2205	protein histidine kinase activity
Ga0080559_RS04780	COG0501	Belongs to the peptidase M48B family
Ga0080559_RS04815	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Ga0080559_RS04820	COG3596	GTP binding
Ga0080559_RS04825	COG0405	Gamma-glutamyltransferase
Ga0080559_RS04850	COG4558	Periplasmic binding protein
Ga0080559_RS04855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Ga0080559_RS04860	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Ga0080559_RS04865	COG1126	abc transporter atp-binding protein
Ga0080559_RS04925	COG0842	Transport permease protein
Ga0080559_RS04945	COG1294	oxidase, subunit
Ga0080559_RS04955	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Ga0080559_RS04965	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Ga0080559_RS04975	COG0736	holo-[acyl-carrier-protein] synthase activity
Ga0080559_RS04980	COG2096	Adenosyltransferase
Ga0080559_RS04990	COG0300	oxidoreductase activity
Ga0080559_RS05000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Ga0080559_RS05010	COG0501	Belongs to the peptidase M48B family
Ga0080559_RS05025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Ga0080559_RS05055	COG1573	uracil-dna glycosylase
Ga0080559_RS05065	COG3191	aminopeptidase activity
Ga0080559_RS05085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080559_RS05100	COG3454	Phosphonate metabolism
Ga0080559_RS05105	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Ga0080559_RS05110	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Ga0080559_RS05115	COG0625	glutathione transferase activity
Ga0080559_RS05120	COG1201	RNA secondary structure unwinding
Ga0080559_RS05135	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Ga0080559_RS05145	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Ga0080559_RS05155	COG4106	trans-aconitate 2-methyltransferase activity
Ga0080559_RS05160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ga0080559_RS05165	COG0037	tRNA processing
Ga0080559_RS05175	COG2885	chlorophyll binding
Ga0080559_RS05180	COG0823	Involved in the tonB-independent uptake of proteins
Ga0080559_RS05200	COG0824	Thioesterase
Ga0080559_RS05220	COG0495	leucyl-tRNA aminoacylation
Ga0080559_RS05225	COG0438	transferase activity, transferring glycosyl groups
Ga0080559_RS05235	COG1403	HNH endonuclease
Ga0080559_RS05255	COG4948	Mandelate Racemase Muconate Lactonizing
Ga0080559_RS05265	COG2301	Belongs to the HpcH HpaI aldolase family
Ga0080559_RS05275	COG4067	protein conserved in archaea
Ga0080559_RS05275	COG0189	ligase activity
Ga0080559_RS05305	COG0583	DNA-binding transcription factor activity
Ga0080559_RS05310	COG3046	protein related to deoxyribodipyrimidine photolyase
Ga0080559_RS05330	COG4221	oxidoreductase activity
Ga0080559_RS05335	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Ga0080559_RS05360	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Ga0080559_RS05365	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Ga0080559_RS05380	COG0356	it plays a direct role in the translocation of protons across the membrane
Ga0080559_RS05390	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Ga0080559_RS05390	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Ga0080559_RS05400	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Ga0080559_RS05420	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Ga0080559_RS05425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Ga0080559_RS05465	COG2132	Multicopper oxidase
Ga0080559_RS05470	COG3909	cytochrome
Ga0080559_RS05495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Ga0080559_RS05495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Ga0080559_RS05500	COG1309	transcriptional regulator
Ga0080559_RS05515	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080559_RS05530	COG0179	Fumarylacetoacetate (FAA) hydrolase
Ga0080559_RS05540	COG2132	Multicopper oxidase
Ga0080559_RS05555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Ga0080559_RS05575	COG0714	Associated with various cellular activities
Ga0080559_RS05585	COG2010	Cytochrome c
Ga0080559_RS05600	COG3794	PFAM blue (type 1) copper domain protein
Ga0080559_RS05610	COG3547	Transposase (IS116 IS110 IS902 family)
Ga0080559_RS05615	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS05620	COG0582	viral genome integration into host DNA
Ga0080559_RS05625	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS05675	COG3547	Transposase (IS116 IS110 IS902 family)
Ga0080559_RS05680	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS05685	COG0582	viral genome integration into host DNA
Ga0080559_RS05690	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS05720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Ga0080559_RS05755	COG1960	acyl-CoA dehydrogenase activity
Ga0080559_RS05760	COG0009	L-threonylcarbamoyladenylate synthase
Ga0080559_RS05765	COG1404	Belongs to the peptidase S8 family
Ga0080559_RS05770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Ga0080559_RS05775	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Ga0080559_RS05780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Ga0080559_RS05780	COG2169	Transcriptional regulator
Ga0080559_RS05790	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
Ga0080559_RS05800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Ga0080559_RS05815	COG1137	ATPase activity
Ga0080559_RS05820	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Ga0080559_RS05825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Ga0080559_RS05850	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Ga0080559_RS05885	COG0443	Heat shock 70 kDa protein
Ga0080559_RS05890	COG0484	heat shock protein binding
Ga0080559_RS05895	COG0586	Pfam SNARE associated Golgi protein
Ga0080559_RS05900	COG2003	Belongs to the UPF0758 family
Ga0080559_RS05905	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Ga0080559_RS05915	COG0653	protein targeting
Ga0080559_RS05920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Ga0080559_RS05925	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Ga0080559_RS05930	COG0494	nUDIX hydrolase
Ga0080559_RS05935	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Ga0080559_RS05950	COG0779	Required for maturation of 30S ribosomal subunits
Ga0080559_RS05960	COG2171	N-acyltransferase activity
Ga0080559_RS05985	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS05990	COG0582	viral genome integration into host DNA
Ga0080559_RS05995	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS06000	COG3547	Transposase (IS116 IS110 IS902 family)
Ga0080559_RS06005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080559_RS06010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Ga0080559_RS06015	COG0557	exoribonuclease II activity
Ga0080559_RS06020	COG2951	lytic endotransglycosylase activity
Ga0080559_RS06025	COG1051	belongs to the nudix hydrolase family
Ga0080559_RS06030	COG0793	Belongs to the peptidase S41A family
Ga0080559_RS06040	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Ga0080559_RS06045	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Ga0080559_RS06050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Ga0080559_RS06055	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Ga0080559_RS06075	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Ga0080559_RS06090	COG0019	diaminopimelate decarboxylase activity
Ga0080559_RS06105	COG0165	Argininosuccinate lyase
Ga0080559_RS06110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Ga0080559_RS06130	COG0287	Prephenate dehydrogenase
Ga0080559_RS06135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Ga0080559_RS06140	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Ga0080559_RS06145	COG0784	Response regulator, receiver
Ga0080559_RS06145	COG5002	protein histidine kinase activity
Ga0080559_RS06150	COG1335	isochorismatase
Ga0080559_RS06155	COG1054	Belongs to the UPF0176 family
Ga0080559_RS06160	COG1338	Plays a role in the flagellum-specific transport system
Ga0080559_RS06165	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Ga0080559_RS06175	COG1766	The M ring may be actively involved in energy transduction
Ga0080559_RS06195	COG3118	belongs to the thioredoxin family
Ga0080559_RS06200	COG1376	ErfK ybiS ycfS ynhG family protein
Ga0080559_RS06215	COG4181	ATPase activity
Ga0080559_RS06230	COG0535	radical SAM domain protein
Ga0080559_RS06235	COG0535	radical SAM domain protein
Ga0080559_RS06240	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
Ga0080559_RS06245	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
Ga0080559_RS06255	COG1607	acyl-coa hydrolase
Ga0080559_RS06260	COG0745	RESPONSE REGULATOR receiver
Ga0080559_RS06265	COG2205	protein histidine kinase activity
Ga0080559_RS06280	COG1131	(ABC) transporter
Ga0080559_RS06295	COG3278	Belongs to the heme-copper respiratory oxidase family
Ga0080559_RS06315	COG3258	Cytochrome c
Ga0080559_RS06320	COG2217	Heavy metal translocating P-type atpase
Ga0080559_RS06370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Ga0080559_RS06370	COG0574	Belongs to the PEP-utilizing enzyme family
Ga0080559_RS06400	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
Ga0080559_RS06415	COG2010	Cytochrome c
Ga0080559_RS06415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Ga0080559_RS06420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Ga0080559_RS06440	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Ga0080559_RS06440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Ga0080559_RS06445	COG1376	ErfK ybiS ycfS ynhG family protein
Ga0080559_RS06465	COG0583	DNA-binding transcription factor activity
Ga0080559_RS06470	COG4638	Rieske (2fe-2S)
Ga0080559_RS06485	COG0019	diaminopimelate decarboxylase activity
Ga0080559_RS06490	COG0243	molybdopterin cofactor binding
Ga0080559_RS06530	COG3791	Glutathione-dependent formaldehyde-activating
Ga0080559_RS06540	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Ga0080559_RS06540	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Ga0080559_RS06545	COG0509	glycine decarboxylation via glycine cleavage system
Ga0080559_RS06550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Ga0080559_RS06555	COG1959	2 iron, 2 sulfur cluster binding
Ga0080559_RS06570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Ga0080559_RS06580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Ga0080559_RS06625	COG1295	ribonuclease BN
Ga0080559_RS06630	COG0628	permease
Ga0080559_RS06650	COG1597	lipid kinase activity
Ga0080559_RS06665	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Ga0080559_RS06675	COG2072	flavoprotein involved in K transport
Ga0080559_RS06680	COG0251	oxidation-reduction process
Ga0080559_RS06690	COG0583	DNA-binding transcription factor activity
Ga0080559_RS06705	COG1127	ABC transporter
Ga0080559_RS06710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Ga0080559_RS06715	COG1492	cobalamin metabolic process
Ga0080559_RS06725	COG2309	aminopeptidase activity
Ga0080559_RS06740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Ga0080559_RS06750	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Ga0080559_RS06755	COG0268	Binds directly to 16S ribosomal RNA
Ga0080559_RS06765	COG1024	Enoyl-CoA hydratase
Ga0080559_RS06770	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Ga0080559_RS06780	COG2226	methyltransferase
Ga0080559_RS06790	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Ga0080559_RS06820	COG5443	negative regulation of bacterial-type flagellum assembly
Ga0080559_RS06840	COG1558	bacterial-type flagellum-dependent cell motility
Ga0080559_RS06845	COG1677	Flagellar hook-basal body complex protein FliE
Ga0080559_RS06850	COG1987	bacterial-type flagellum assembly
Ga0080559_RS06855	COG4786	Flagellar basal body rod
Ga0080559_RS06860	COG4786	Flagellar basal body rod
Ga0080559_RS06870	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Ga0080559_RS06885	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Ga0080559_RS06895	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Ga0080559_RS06905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Ga0080559_RS06910	COG1706	bacterial-type flagellum-dependent cell motility
Ga0080559_RS06930	COG1360	Flagellar Motor Protein
Ga0080559_RS06935	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Ga0080559_RS06955	COG3474	cytochrome
Ga0080559_RS06960	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Ga0080559_RS06965	COG2840	Smr protein MutS2
Ga0080559_RS06985	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Ga0080559_RS06995	COG0237	dephospho-CoA kinase activity
Ga0080559_RS07000	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Ga0080559_RS07005	COG0424	maF-like protein
Ga0080559_RS07010	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Ga0080559_RS07015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Ga0080559_RS07020	COG0445	tRNA wobble uridine modification
Ga0080559_RS07025	COG0357	Ribosomal RNA small subunit methyltransferase G
Ga0080559_RS07040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Ga0080559_RS07045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Ga0080559_RS07050	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Ga0080559_RS07055	COG1420	regulation of RNA biosynthetic process
Ga0080559_RS07060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Ga0080559_RS07065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Ga0080559_RS07070	COG0280	phosphate acetyltransferase
Ga0080559_RS07070	COG0281	malic enzyme
Ga0080559_RS07075	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Ga0080559_RS07075	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Ga0080559_RS07080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Ga0080559_RS07085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Ga0080559_RS07105	COG0137	argininosuccinate synthase activity
Ga0080559_RS07115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Ga0080559_RS07125	COG0745	RESPONSE REGULATOR receiver
Ga0080559_RS07140	COG0494	nUDIX hydrolase
Ga0080559_RS07145	COG0617	tRNA 3'-terminal CCA addition
Ga0080559_RS07155	COG1132	(ABC) transporter
Ga0080559_RS07160	COG1132	(ABC) transporter
Ga0080559_RS07165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Ga0080559_RS07170	COG3034	peptidoglycan biosynthetic process
Ga0080559_RS07195	COG2226	methyltransferase
Ga0080559_RS07220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Ga0080559_RS07250	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Ga0080559_RS07255	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Ga0080559_RS07270	COG1074	ATP-dependent DNA helicase activity
Ga0080559_RS07275	COG2887	Belongs to the helicase family. UvrD subfamily
Ga0080559_RS07280	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Ga0080559_RS07285	COG3178	'Phosphotransferase
Ga0080559_RS07290	COG0802	atpase or kinase
Ga0080559_RS07305	COG1999	signal sequence binding
Ga0080559_RS07310	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Ga0080559_RS07320	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
Ga0080559_RS07330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Ga0080559_RS07335	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Ga0080559_RS07345	COG1115	amino acid carrier protein
Ga0080559_RS07370	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Ga0080559_RS07375	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Ga0080559_RS07400	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Ga0080559_RS07405	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Ga0080559_RS07410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Ga0080559_RS07410	COG0517	IMP dehydrogenase activity
Ga0080559_RS07430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Ga0080559_RS07440	COG0438	transferase activity, transferring glycosyl groups
Ga0080559_RS07480	COG0489	protein tyrosine kinase activity
Ga0080559_RS07485	COG0673	inositol 2-dehydrogenase activity
Ga0080559_RS07495	COG0297	glycogen (starch) synthase activity
Ga0080559_RS07495	COG0438	transferase activity, transferring glycosyl groups
Ga0080559_RS07525	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Ga0080559_RS07525	COG2755	lipolytic protein G-D-S-L family
Ga0080559_RS07530	COG0438	transferase activity, transferring glycosyl groups
Ga0080559_RS07545	COG0243	molybdopterin cofactor binding
Ga0080559_RS07555	COG0437	4 iron, 4 sulfur cluster binding
Ga0080559_RS07595	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080559_RS07610	COG0071	Belongs to the small heat shock protein (HSP20) family
Ga0080559_RS07620	COG3591	Belongs to the peptidase S1B family
Ga0080559_RS07625	COG0247	lactate metabolic process
Ga0080559_RS07635	COG0277	FAD linked oxidase domain protein
Ga0080559_RS07640	COG0277	FAD linked oxidase domain protein
Ga0080559_RS07665	COG0544	peptidyl-prolyl cis-trans isomerase activity
Ga0080559_RS07700	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Ga0080559_RS07705	COG0285	dihydrofolate synthase activity
Ga0080559_RS07710	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Ga0080559_RS07715	COG2271	Major facilitator Superfamily
Ga0080559_RS07725	COG1671	Belongs to the UPF0178 family
Ga0080559_RS07730	COG0679	Auxin Efflux Carrier
Ga0080559_RS07740	COG1131	(ABC) transporter
Ga0080559_RS07770	COG0714	Associated with various cellular activities
Ga0080559_RS07790	COG0791	NLP P60 protein
Ga0080559_RS07795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Ga0080559_RS07805	COG0288	reversible hydration of carbon dioxide
Ga0080559_RS07830	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Ga0080559_RS07835	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Ga0080559_RS07850	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Ga0080559_RS07870	COG0346	lactoylglutathione lyase activity
Ga0080559_RS07885	COG0778	Nitroreductase
Ga0080559_RS07890	COG1872	DUF167
Ga0080559_RS07930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080559_RS07935	COG1177	transmembrane transport
Ga0080559_RS07940	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080559_RS07945	COG3842	ATPase activity
Ga0080559_RS07955	COG1802	Transcriptional regulator
Ga0080559_RS07965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Ga0080559_RS07975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Ga0080559_RS07985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Ga0080559_RS08010	COG0284	orotidine-5'-phosphate decarboxylase activity
Ga0080559_RS08025	COG0069	glutamate synthase activity
Ga0080559_RS08030	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Ga0080559_RS08075	COG1215	transferase activity, transferring glycosyl groups
Ga0080559_RS08085	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Ga0080559_RS08095	COG2197	response regulator
Ga0080559_RS08110	COG4175	Glycine betaine
Ga0080559_RS08130	COG3119	arylsulfatase activity
Ga0080559_RS08175	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Ga0080559_RS08180	COG1618	nucleotide phosphatase activity, acting on free nucleotides
Ga0080559_RS08180	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Ga0080559_RS08190	COG0746	molybdenum cofactor guanylyltransferase activity
Ga0080559_RS08195	COG1763	Mo-molybdopterin cofactor biosynthetic process
Ga0080559_RS08200	COG0303	'Molybdopterin
Ga0080559_RS08205	COG0425	Belongs to the sulfur carrier protein TusA family
Ga0080559_RS08220	COG0489	protein tyrosine kinase activity
Ga0080559_RS08260	COG3383	formate dehydrogenase (NAD+) activity
Ga0080559_RS08260	COG0243	molybdopterin cofactor binding
Ga0080559_RS08265	COG0437	4 iron, 4 sulfur cluster binding
Ga0080559_RS08275	COG3474	cytochrome
Ga0080559_RS08290	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Ga0080559_RS08335	COG1129	ABC transporter
Ga0080559_RS08340	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS08345	COG1879	ABC-type sugar transport system periplasmic component
Ga0080559_RS08360	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Ga0080559_RS08385	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Ga0080559_RS08390	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Ga0080559_RS08395	COG2423	ornithine cyclodeaminase activity
Ga0080559_RS08400	COG3639	organic phosphonate transmembrane transporter activity
Ga0080559_RS08405	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Ga0080559_RS08410	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
Ga0080559_RS08440	COG0246	Mannitol dehydrogenase
Ga0080559_RS08445	COG2721	sulfolactate sulfo-lyase activity
Ga0080559_RS08465	COG1175	transmembrane transport
Ga0080559_RS08485	COG3842	ATPase activity
Ga0080559_RS08490	COG3842	ATPase activity
Ga0080559_RS08495	COG0395	ABC-type sugar transport system, permease component
Ga0080559_RS08500	COG1175	transmembrane transport
Ga0080559_RS08505	COG1653	transport
Ga0080559_RS08530	COG0277	FAD linked oxidase domain protein
Ga0080559_RS08535	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Ga0080559_RS08540	COG0765	amino acid transport
Ga0080559_RS08545	COG0765	amino acid transport
Ga0080559_RS08550	COG1126	abc transporter atp-binding protein
Ga0080559_RS08555	COG2188	Transcriptional regulator
Ga0080559_RS08560	COG0583	DNA-binding transcription factor activity
Ga0080559_RS08565	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Ga0080559_RS08575	COG2986	histidine ammonia-lyase
Ga0080559_RS08580	COG1228	amidohydrolase
Ga0080559_RS08590	COG4191	Histidine kinase
Ga0080559_RS08610	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
Ga0080559_RS08660	COG0375	protein maturation
Ga0080559_RS08690	COG4604	ABC transporter, ATP-binding protein
Ga0080559_RS08695	COG4605	iron ion homeostasis
Ga0080559_RS08700	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Ga0080559_RS08705	COG4607	ABC-type enterochelin transport system periplasmic component
Ga0080559_RS08740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080559_RS08755	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080559_RS08760	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Ga0080559_RS08765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Ga0080559_RS08770	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Ga0080559_RS08775	COG0659	secondary active sulfate transmembrane transporter activity
Ga0080559_RS08785	COG0254	rRNA binding
Ga0080559_RS08790	COG0335	large ribosomal subunit rRNA binding
Ga0080559_RS08800	COG0336	Belongs to the RNA methyltransferase TrmD family
Ga0080559_RS08810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Ga0080559_RS08820	COG0228	four-way junction DNA binding
Ga0080559_RS08845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Ga0080559_RS08875	COG0356	it plays a direct role in the translocation of protons across the membrane
Ga0080559_RS08880	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Ga0080559_RS08885	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Ga0080559_RS08890	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Ga0080559_RS08895	COG0489	protein tyrosine kinase activity
Ga0080559_RS08895	COG2151	metal-sulfur cluster biosynthetic enzyme
Ga0080559_RS08920	COG0402	S-adenosylhomocysteine deaminase activity
Ga0080559_RS08925	COG1079	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS08930	COG4603	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS08935	COG3845	ABC transporter
Ga0080559_RS08965	COG2897	thiosulfate sulfurtransferase activity
Ga0080559_RS08970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Ga0080559_RS08975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Ga0080559_RS08995	COG0202	RNA polymerase activity
Ga0080559_RS09000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Ga0080559_RS09005	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Ga0080559_RS09015	COG0563	adenylate kinase activity
Ga0080559_RS09020	COG0201	protein transport
Ga0080559_RS09025	COG0200	Binds to the 23S rRNA
Ga0080559_RS09030	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Ga0080559_RS09045	COG2351	hydroxyisourate hydrolase activity
Ga0080559_RS09055	COG3257	ureidoglycine aminohydrolase activity
Ga0080559_RS09060	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
Ga0080559_RS09090	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Ga0080559_RS09130	COG0446	pyridine nucleotide-disulphide oxidoreductase
Ga0080559_RS09130	COG1902	pentaerythritol trinitrate reductase activity
Ga0080559_RS09135	COG0693	protein deglycase activity
Ga0080559_RS09140	COG0583	DNA-binding transcription factor activity
Ga0080559_RS09170	COG1546	Belongs to the CinA family
Ga0080559_RS09170	COG1058	Belongs to the CinA family
Ga0080559_RS09175	COG1489	DNA binding
Ga0080559_RS09180	COG0668	transmembrane transport
Ga0080559_RS09185	COG0024	Methionine aminopeptidase
Ga0080559_RS09195	COG0742	ribosomal rna small subunit methyltransferase
Ga0080559_RS09205	COG0678	peroxiredoxin activity
Ga0080559_RS09225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ga0080559_RS09245	COG2154	pterin-4-alpha-carbinolamine dehydratase
Ga0080559_RS09260	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Ga0080559_RS09265	COG0142	geranyltranstransferase activity
Ga0080559_RS09275	COG2813	Specifically methylates the guanine in position
Ga0080559_RS09285	COG0346	lactoylglutathione lyase activity
Ga0080559_RS09310	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Ga0080559_RS09330	COG1309	transcriptional regulator
Ga0080559_RS09355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080559_RS09360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080559_RS09365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ga0080559_RS09375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Ga0080559_RS09380	COG1609	Transcriptional regulator
Ga0080559_RS09575	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Ga0080559_RS09590	COG0732	type I restriction modification DNA specificity domain
Ga0080559_RS09595	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Ga0080559_RS09615	COG0798	PFAM Bile acid sodium symporter
Ga0080559_RS09625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Ga0080559_RS09635	COG4774	siderophore transport
Ga0080559_RS09640	COG2814	Major facilitator Superfamily
Ga0080559_RS09690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Ga0080559_RS09695	COG3383	formate dehydrogenase (NAD+) activity
Ga0080559_RS09710	COG0583	DNA-binding transcription factor activity
Ga0080559_RS09715	COG2111	Na H antiporter
Ga0080559_RS09715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Ga0080559_RS09720	COG1006	Multisubunit Na H antiporter MnhC subunit
Ga0080559_RS09725	COG0651	ATP synthesis coupled electron transport
Ga0080559_RS09735	COG2212	antiporter activity
Ga0080559_RS09740	COG1320	monovalent cation:proton antiporter activity
Ga0080559_RS09755	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Ga0080559_RS09760	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Ga0080559_RS09770	COG0706	membrane insertase activity
Ga0080559_RS09775	COG5001	Diguanylate cyclase
Ga0080559_RS09775	COG3300	MHYT domain
Ga0080559_RS09780	COG0037	tRNA processing
Ga0080559_RS09785	COG2032	superoxide dismutase activity
Ga0080559_RS09790	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Ga0080559_RS09795	COG0594	ribonuclease P activity
Ga0080559_RS09800	COG0230	Belongs to the bacterial ribosomal protein bL34 family
Ga0080559_RS09815	COG4191	Histidine kinase
Ga0080559_RS09825	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Ga0080559_RS09835	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Ga0080559_RS09840	COG0792	nuclease activity
Ga0080559_RS09850	COG0657	acetylesterase activity
Ga0080559_RS09855	COG0606	chelatase, subunit chli
Ga0080559_RS09880	COG0756	dUTP diphosphatase activity
Ga0080559_RS09885	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Ga0080559_RS09890	COG0339	signal peptide processing
Ga0080559_RS09900	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS09905	COG0459	protein refolding
Ga0080559_RS09910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Ga0080559_RS09915	COG0697	spore germination
Ga0080559_RS09925	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Ga0080559_RS09940	COG0840	transmembrane signaling receptor activity
Ga0080559_RS09945	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Ga0080559_RS09950	COG4143	(ABC) transporter
Ga0080559_RS09960	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Ga0080559_RS09985	COG2824	Alkylphosphonate utilization operon protein PhnA
Ga0080559_RS09990	COG1183	phosphatidylcholine synthase activity
Ga0080559_RS09995	COG0688	phosphatidylethanolamine metabolic process
Ga0080559_RS10020	COG0745	RESPONSE REGULATOR receiver
Ga0080559_RS10040	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Ga0080559_RS10070	COG0250	Participates in transcription elongation, termination and antitermination
Ga0080559_RS10075	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Ga0080559_RS10080	COG0081	regulation of translation
Ga0080559_RS10090	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Ga0080559_RS10095	COG0222	ribosome binding
Ga0080559_RS10100	COG0085	RNA polymerase activity
Ga0080559_RS10105	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Ga0080559_RS10110	COG0697	spore germination
Ga0080559_RS10120	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Ga0080559_RS10125	COG0049	tRNA binding
Ga0080559_RS10130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Ga0080559_RS10135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Ga0080559_RS10140	COG0051	transcription antitermination factor activity, RNA binding
Ga0080559_RS10145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Ga0080559_RS10150	COG0088	Forms part of the polypeptide exit tunnel
Ga0080559_RS10155	COG0089	rRNA binding
Ga0080559_RS10160	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Ga0080559_RS10165	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Ga0080559_RS10170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Ga0080559_RS10175	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Ga0080559_RS10180	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Ga0080559_RS10200	COG0255	Belongs to the universal ribosomal protein uL29 family
Ga0080559_RS10205	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Ga0080559_RS10210	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Ga0080559_RS10215	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Ga0080559_RS10220	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Ga0080559_RS10225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Ga0080559_RS10230	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Ga0080559_RS10235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Ga0080559_RS10240	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Ga0080559_RS10245	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Ga0080559_RS10250	COG1841	ribosomal large subunit assembly
Ga0080559_RS10260	COG1126	abc transporter atp-binding protein
Ga0080559_RS10265	COG0765	amino acid transport
Ga0080559_RS10270	COG4597	amino acid ABC transporter
Ga0080559_RS10275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Ga0080559_RS10285	COG0546	phosphoglycolate phosphatase activity
Ga0080559_RS10290	COG0564	pseudouridine synthase activity
Ga0080559_RS10305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Ga0080559_RS10315	COG1496	oxidoreductase activity
Ga0080559_RS10325	COG1522	sequence-specific DNA binding
Ga0080559_RS10330	COG0492	ferredoxin-NADP+ reductase activity
Ga0080559_RS10335	COG2046	Belongs to the sulfate adenylyltransferase family
Ga0080559_RS10335	COG0529	Catalyzes the synthesis of activated sulfate
Ga0080559_RS10370	COG2183	response to ionizing radiation
Ga0080559_RS10375	COG1803	Methylglyoxal synthase
Ga0080559_RS10385	COG2135	peptidase activity
Ga0080559_RS10390	COG1024	Enoyl-CoA hydratase
Ga0080559_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS10405	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS10415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Ga0080559_RS10425	COG1674	ftsk spoiiie
Ga0080559_RS10455	COG2983	Belongs to the UPF0260 family
Ga0080559_RS10460	COG0196	riboflavin kinase activity
Ga0080559_RS10465	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Ga0080559_RS10470	COG0457	Tetratricopeptide repeat
Ga0080559_RS10495	COG0469	pyruvate kinase activity
Ga0080559_RS10500	COG0840	transmembrane signaling receptor activity
Ga0080559_RS10510	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Ga0080559_RS10515	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Ga0080559_RS10535	COG3547	Transposase (IS116 IS110 IS902 family)
Ga0080559_RS10540	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS10545	COG0582	viral genome integration into host DNA
Ga0080559_RS10550	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS10585	COG2801	Transposase and inactivated derivatives
Ga0080559_RS10600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080559_RS10630	COG0601	transmembrane transport
Ga0080559_RS10635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080559_RS10645	COG1522	sequence-specific DNA binding
Ga0080559_RS10655	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080559_RS10670	COG0604	alcohol dehydrogenase
Ga0080559_RS10680	COG2801	Transposase and inactivated derivatives
Ga0080559_RS10685	COG3547	Transposase (IS116 IS110 IS902 family)
Ga0080559_RS10690	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS10695	COG0582	viral genome integration into host DNA
Ga0080559_RS10700	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS10710	COG2433	Pfam Transposase IS66
Ga0080559_RS10720	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Ga0080559_RS10740	COG3243	poly(R)-hydroxyalkanoic acid synthase
Ga0080559_RS10755	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080559_RS10765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Ga0080559_RS10775	COG1660	Displays ATPase and GTPase activities
Ga0080559_RS10785	COG2205	protein histidine kinase activity
Ga0080559_RS10790	COG0745	RESPONSE REGULATOR receiver
Ga0080559_RS10795	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Ga0080559_RS10820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Ga0080559_RS10825	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Ga0080559_RS10830	COG1490	D-aminoacyl-tRNA deacylase activity
Ga0080559_RS10875	COG3853	Toxic anion resistance protein (TelA)
Ga0080559_RS10895	COG1187	pseudouridine synthase activity
Ga0080559_RS10900	COG0590	tRNA wobble adenosine to inosine editing
Ga0080559_RS10915	COG0708	Exodeoxyribonuclease III
Ga0080559_RS10920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Ga0080559_RS10935	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Ga0080559_RS10940	COG2835	tetraacyldisaccharide 4'-kinase activity
Ga0080559_RS10950	COG0543	2 iron, 2 sulfur cluster binding
Ga0080559_RS10950	COG0633	Ferredoxin
Ga0080559_RS10970	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Ga0080559_RS10980	COG1185	polyribonucleotide nucleotidyltransferase activity
Ga0080559_RS10990	COG0753	catalase activity
Ga0080559_RS11005	COG0129	dihydroxy-acid dehydratase activity
Ga0080559_RS11010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Ga0080559_RS11015	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Ga0080559_RS11035	COG0625	glutathione transferase activity
Ga0080559_RS11040	COG1970	mechanosensitive ion channel activity
Ga0080559_RS11045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Ga0080559_RS11050	COG0686	Belongs to the AlaDH PNT family
Ga0080559_RS11080	COG0348	domain, Protein
Ga0080559_RS11085	COG0583	DNA-binding transcription factor activity
Ga0080559_RS11090	COG2010	Cytochrome c
Ga0080559_RS11120	COG5507	3-demethylubiquinone-9 3-methyltransferase
Ga0080559_RS11125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Ga0080559_RS11130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Ga0080559_RS11135	COG4172	Belongs to the ABC transporter superfamily
Ga0080559_RS11140	COG4239	(ABC) transporter, permease
Ga0080559_RS11145	COG4174	ABC transporter (Permease)
Ga0080559_RS11160	COG0077	Prephenate dehydratase
Ga0080559_RS11185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Ga0080559_RS11195	COG0358	DNA primase activity
Ga0080559_RS11200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Ga0080559_RS11225	COG0432	Pfam Uncharacterised protein family UPF0047
Ga0080559_RS11235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Ga0080559_RS11235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Ga0080559_RS11250	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Ga0080559_RS11255	COG0039	L-malate dehydrogenase activity
Ga0080559_RS11260	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Ga0080559_RS11265	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Ga0080559_RS11270	COG0124	histidyl-tRNA synthetase
Ga0080559_RS11305	COG3845	ABC transporter
Ga0080559_RS11310	COG4603	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS11315	COG1079	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS11335	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Ga0080559_RS11340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Ga0080559_RS11375	COG1742	UPF0060 membrane protein
Ga0080559_RS11380	COG4372	Transposase
Ga0080559_RS11400	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS11405	COG0582	viral genome integration into host DNA
Ga0080559_RS11410	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS11415	COG3547	Transposase (IS116 IS110 IS902 family)
Ga0080559_RS11465	COG0420	3'-5' exonuclease activity
Ga0080559_RS11470	COG0583	DNA-binding transcription factor activity
Ga0080559_RS11515	COG0583	DNA-binding transcription factor activity
Ga0080559_RS11530	COG2223	nitrite transmembrane transporter activity
Ga0080559_RS11535	COG2815	serine threonine protein kinase
Ga0080559_RS11535	COG0515	serine threonine protein kinase
Ga0080559_RS11540	COG0243	molybdopterin cofactor binding
Ga0080559_RS11545	COG2146	nitrite reductase [NAD(P)H] activity
Ga0080559_RS11550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Ga0080559_RS11570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Ga0080559_RS11575	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080559_RS11580	COG3842	ATPase activity
Ga0080559_RS11600	COG1737	Transcriptional regulator
Ga0080559_RS11605	COG3842	ATPase activity
Ga0080559_RS11620	COG1175	transmembrane transport
Ga0080559_RS11625	COG1653	transport
Ga0080559_RS11645	COG0583	DNA-binding transcription factor activity
Ga0080559_RS11650	COG3842	ATPase activity
Ga0080559_RS11655	COG1175	transmembrane transport
Ga0080559_RS11660	COG0395	ABC-type sugar transport system, permease component
Ga0080559_RS11705	COG4993	Dehydrogenase
Ga0080559_RS11710	COG3547	Transposase (IS116 IS110 IS902 family)
Ga0080559_RS11715	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS11720	COG0582	viral genome integration into host DNA
Ga0080559_RS11725	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS11770	COG1309	transcriptional regulator
Ga0080559_RS11785	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Ga0080559_RS11800	COG0850	regulation of cytokinetic process
Ga0080559_RS11805	COG2894	cell division
Ga0080559_RS11810	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Ga0080559_RS11830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Ga0080559_RS11845	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Ga0080559_RS11855	COG0745	RESPONSE REGULATOR receiver
Ga0080559_RS11875	COG2391	methyltransferase activity
Ga0080559_RS11890	COG4176	ABC-type proline glycine betaine transport system permease component
Ga0080559_RS11900	COG2954	triphosphatase activity
Ga0080559_RS11910	COG4336	lyase activity
Ga0080559_RS11915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Ga0080559_RS11925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080559_RS11940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Ga0080559_RS11955	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS11970	COG1129	ABC transporter
Ga0080559_RS11975	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS11980	COG2390	Transcriptional regulator
Ga0080559_RS11985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Ga0080559_RS11995	COG1830	Aldolase
Ga0080559_RS12000	COG3347	Dehydrogenase
Ga0080559_RS12000	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS12005	COG0587	DNA-directed DNA polymerase activity
Ga0080559_RS12020	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080559_RS12025	COG0473	3-isopropylmalate dehydrogenase activity
Ga0080559_RS12055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Ga0080559_RS12060	COG1780	Probably involved in ribonucleotide reductase function
Ga0080559_RS12065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Ga0080559_RS12070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Ga0080559_RS12075	COG0754	glutathionylspermidine amidase activity
Ga0080559_RS12080	COG5463	Belongs to the UPF0441 family
Ga0080559_RS12100	COG0131	Imidazoleglycerol-phosphate dehydratase
Ga0080559_RS12120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Ga0080559_RS12135	COG3768	UPF0283 membrane protein
Ga0080559_RS12145	COG3106	COG3106 Predicted ATPase
Ga0080559_RS12150	COG0306	phosphate transporter
Ga0080559_RS12165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Ga0080559_RS12170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Ga0080559_RS12175	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
Ga0080559_RS12180	COG1643	Atp-dependent helicase
Ga0080559_RS12185	COG1703	isobutyryl-CoA mutase activity
Ga0080559_RS12195	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Ga0080559_RS12210	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Ga0080559_RS12215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Ga0080559_RS12230	COG0504	CTP synthase activity
Ga0080559_RS12270	COG1832	CoA-binding protein
Ga0080559_RS12275	COG0140	phosphoribosyl-ATP diphosphatase activity
Ga0080559_RS12280	COG0107	imidazoleglycerol-phosphate synthase activity
Ga0080559_RS12295	COG0248	Ppx GppA phosphatase
Ga0080559_RS12305	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Ga0080559_RS12315	COG0628	permease
Ga0080559_RS12320	COG0442	prolyl-tRNA aminoacylation
Ga0080559_RS12330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Ga0080559_RS12335	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Ga0080559_RS12340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Ga0080559_RS12345	COG3409	Peptidoglycan-binding domain 1 protein
Ga0080559_RS12345	COG3773	Cell wall hydrolase
Ga0080559_RS12350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Ga0080559_RS12350	COG0574	Belongs to the PEP-utilizing enzyme family
Ga0080559_RS12355	COG0751	glycine-tRNA ligase activity
Ga0080559_RS12370	COG0752	glycyl-tRNA synthetase alpha subunit
Ga0080559_RS12380	COG1380	Effector of murein hydrolase LrgA
Ga0080559_RS12385	COG1346	cytolysis
Ga0080559_RS12390	COG2610	gluconate transmembrane transporter activity
Ga0080559_RS12435	COG1802	Transcriptional regulator
Ga0080559_RS12480	COG0321	lipoyl(octanoyl) transferase activity
Ga0080559_RS12490	COG5001	Diguanylate cyclase
Ga0080559_RS12500	COG0729	surface antigen
Ga0080559_RS12530	COG0737	Belongs to the 5'-nucleotidase family
Ga0080559_RS12545	COG4136	ATPase activity
Ga0080559_RS12550	COG4135	transport system, permease component
Ga0080559_RS12555	COG4134	Bacterial extracellular solute-binding protein
Ga0080559_RS12560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Ga0080559_RS12590	COG4451	ribulose bisphosphate carboxylase, small
Ga0080559_RS12595	COG1850	ribulose-bisphosphate carboxylase activity
Ga0080559_RS12605	COG0126	phosphoglycerate kinase activity
Ga0080559_RS12625	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Ga0080559_RS12655	COG2226	methyltransferase
Ga0080559_RS12665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080559_RS12700	COG1278	Cold shock
Ga0080559_RS12720	COG4191	Histidine kinase
Ga0080559_RS12720	COG0784	Response regulator, receiver
Ga0080559_RS12730	COG1280	lysine exporter protein (LysE YggA)
Ga0080559_RS12745	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Ga0080559_RS12770	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Ga0080559_RS12785	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Ga0080559_RS12790	COG1132	(ABC) transporter
Ga0080559_RS12800	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Ga0080559_RS12810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Ga0080559_RS12820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Ga0080559_RS12830	COG1136	(ABC) transporter
Ga0080559_RS12865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Ga0080559_RS12880	COG2124	cytochrome p450
Ga0080559_RS12910	COG3436	PFAM IS66 Orf2 family protein
Ga0080559_RS12915	COG2433	Pfam Transposase IS66
Ga0080559_RS12925	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Ga0080559_RS12940	COG4584	PFAM Integrase catalytic
Ga0080559_RS12945	COG1484	DNA-dependent DNA replication
Ga0080559_RS12965	COG4717	serine-type aminopeptidase activity
Ga0080559_RS12970	COG0420	3'-5' exonuclease activity
Ga0080559_RS13060	COG5489	Protein of unknown function (DUF736)
Ga0080559_RS13110	COG0741	lytic transglycosylase activity
Ga0080559_RS13140	COG4962	Type ii secretion system protein e
Ga0080559_RS13155	COG3451	type IV secretory pathway VirB4
Ga0080559_RS13170	COG3846	protein secretion by the type IV secretion system
Ga0080559_RS13185	COG2948	multi-organism process
Ga0080559_RS13195	COG0583	DNA-binding transcription factor activity
Ga0080559_RS13200	COG2217	Heavy metal translocating P-type atpase
Ga0080559_RS13230	COG1999	signal sequence binding
Ga0080559_RS13235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Ga0080559_RS13245	COG0330	HflC and HflK could
Ga0080559_RS13250	COG0330	HflC and HflK could
Ga0080559_RS13260	COG2205	protein histidine kinase activity
Ga0080559_RS13270	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Ga0080559_RS13275	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Ga0080559_RS13295	COG1999	signal sequence binding
Ga0080559_RS13315	COG1999	signal sequence binding
Ga0080559_RS13330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Ga0080559_RS13335	COG0730	response to heat
Ga0080559_RS13345	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Ga0080559_RS13355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080559_RS13370	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Ga0080559_RS13370	COG0446	pyridine nucleotide-disulphide oxidoreductase
Ga0080559_RS13390	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Ga0080559_RS13390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080559_RS13400	COG2030	dehydratase
Ga0080559_RS13425	COG0659	secondary active sulfate transmembrane transporter activity
Ga0080559_RS13430	COG1227	inorganic diphosphatase activity
Ga0080559_RS13440	COG0280	phosphate acetyltransferase
Ga0080559_RS13440	COG0281	malic enzyme
Ga0080559_RS13455	COG0346	lactoylglutathione lyase activity
Ga0080559_RS13460	COG3237	CsbD-like
Ga0080559_RS13465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Ga0080559_RS13470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Ga0080559_RS13475	COG0450	alkyl hydroperoxide reductase
Ga0080559_RS13485	COG0564	pseudouridine synthase activity
Ga0080559_RS13490	COG0183	Belongs to the thiolase family
Ga0080559_RS13495	COG1366	Belongs to the anti-sigma-factor antagonist family
Ga0080559_RS13505	COG3152	Membrane
Ga0080559_RS13560	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Ga0080559_RS13565	COG0109	protoheme IX farnesyltransferase activity
Ga0080559_RS13575	COG0312	modulator of DNA gyrase
Ga0080559_RS13580	COG0758	DNA mediated transformation
Ga0080559_RS13585	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Ga0080559_RS13625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Ga0080559_RS13630	COG1280	lysine exporter protein (LysE YggA)
Ga0080559_RS13635	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Ga0080559_RS13640	COG0659	secondary active sulfate transmembrane transporter activity
Ga0080559_RS13670	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Ga0080559_RS13675	COG0527	aspartate kinase activity
Ga0080559_RS13685	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS13695	COG1519	Transferase
Ga0080559_RS13715	COG0556	nucleotide-excision repair
Ga0080559_RS13730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Ga0080559_RS13735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080559_RS13750	COG0235	Class ii aldolase
Ga0080559_RS13755	COG0747	negative chemotaxis
Ga0080559_RS13760	COG0601	transmembrane transport
Ga0080559_RS13765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080559_RS13775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Ga0080559_RS13780	COG0154	amidase activity
Ga0080559_RS13785	COG0513	Belongs to the DEAD box helicase family
Ga0080559_RS13790	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Ga0080559_RS13810	COG0308	aminopeptidase N
Ga0080559_RS13825	COG1279	arginine transmembrane transporter activity
Ga0080559_RS13855	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Ga0080559_RS13880	COG1793	dna ligase
Ga0080559_RS13910	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
Ga0080559_RS13915	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Ga0080559_RS13920	COG1329	Transcriptional regulator
Ga0080559_RS13935	COG1469	GTP cyclohydrolase I activity
Ga0080559_RS13945	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Ga0080559_RS13950	COG0525	valine-tRNA ligase activity
Ga0080559_RS13960	COG0489	protein tyrosine kinase activity
Ga0080559_RS13970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Ga0080559_RS13975	COG1686	Belongs to the peptidase S11 family
Ga0080559_RS13990	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080559_RS13995	COG0366	Alpha amylase catalytic
Ga0080559_RS14010	COG2124	cytochrome p450
Ga0080559_RS14020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Ga0080559_RS14025	COG0366	Alpha amylase catalytic
Ga0080559_RS14035	COG1136	(ABC) transporter
Ga0080559_RS14050	COG2273	Hydrolase Family 16
Ga0080559_RS14050	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
Ga0080559_RS14075	COG1215	transferase activity, transferring glycosyl groups
Ga0080559_RS14095	COG1366	Belongs to the anti-sigma-factor antagonist family
Ga0080559_RS14100	COG0745	RESPONSE REGULATOR receiver
Ga0080559_RS14110	COG4608	Belongs to the ABC transporter superfamily
Ga0080559_RS14115	COG0444	Belongs to the ABC transporter superfamily
Ga0080559_RS14120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080559_RS14125	COG0601	transmembrane transport
Ga0080559_RS14135	COG1802	Transcriptional regulator
Ga0080559_RS14165	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080559_RS14185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Ga0080559_RS14190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080559_RS14195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Ga0080559_RS14200	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Ga0080559_RS14210	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS14215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Ga0080559_RS14220	COG0583	DNA-binding transcription factor activity
Ga0080559_RS14230	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080559_RS14240	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Ga0080559_RS14270	COG0601	transmembrane transport
Ga0080559_RS14300	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Ga0080559_RS14305	COG1845	cytochrome c oxidase, subunit III
Ga0080559_RS14310	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Ga0080559_RS14315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Ga0080559_RS14325	COG4302	ethanolamine ammonia-lyase activity
Ga0080559_RS14340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Ga0080559_RS14345	COG1349	DNA-binding transcription factor activity
Ga0080559_RS14365	COG3842	ATPase activity
Ga0080559_RS14370	COG1177	transmembrane transport
Ga0080559_RS14375	COG1177	transmembrane transport
Ga0080559_RS14385	COG1335	isochorismatase
Ga0080559_RS14390	COG1846	Transcriptional regulator
Ga0080559_RS14465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Ga0080559_RS14470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Ga0080559_RS14475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Ga0080559_RS14485	COG0433	COG0433 Predicted ATPase
Ga0080559_RS14510	COG4166	transmembrane transport
Ga0080559_RS14515	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS14545	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Ga0080559_RS14555	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Ga0080559_RS14580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080559_RS14590	COG0156	8-amino-7-oxononanoate synthase activity
Ga0080559_RS14600	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Ga0080559_RS14610	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Ga0080559_RS14610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Ga0080559_RS14620	COG0436	Aminotransferase
Ga0080559_RS14625	COG0860	N-Acetylmuramoyl-L-alanine amidase
Ga0080559_RS14630	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Ga0080559_RS14635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Ga0080559_RS14660	COG0028	Belongs to the TPP enzyme family
Ga0080559_RS14680	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Ga0080559_RS14690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080559_RS14705	COG0583	DNA-binding transcription factor activity
Ga0080559_RS14710	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080559_RS14725	COG3842	ATPase activity
Ga0080559_RS14730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Ga0080559_RS14735	COG3246	L-lysine catabolic process to acetate
Ga0080559_RS14750	COG0583	DNA-binding transcription factor activity
Ga0080559_RS14755	COG1960	acyl-CoA dehydrogenase activity
Ga0080559_RS14760	COG1272	protein, Hemolysin III
Ga0080559_RS14765	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080559_RS14765	COG1024	Enoyl-CoA hydratase
Ga0080559_RS14770	COG0183	Belongs to the thiolase family
Ga0080559_RS14775	COG0625	glutathione transferase activity
Ga0080559_RS14785	COG1960	acyl-CoA dehydrogenase activity
Ga0080559_RS14810	COG0534	Mate efflux family protein
Ga0080559_RS14820	COG0133	tryptophan synthase activity
Ga0080559_RS14825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Ga0080559_RS14850	COG0277	FAD linked oxidase domain protein
Ga0080559_RS14860	COG0038	chloride channel
Ga0080559_RS14905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080559_RS14910	COG0601	transmembrane transport
Ga0080559_RS14925	COG4172	Belongs to the ABC transporter superfamily
Ga0080559_RS14930	COG0235	Class ii aldolase
Ga0080559_RS14935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080559_RS14940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080559_RS14945	COG1473	amidohydrolase
Ga0080559_RS14960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Ga0080559_RS14965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Ga0080559_RS14975	COG0215	cysteine-tRNA ligase activity
Ga0080559_RS14980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Ga0080559_RS14995	COG2814	Major facilitator Superfamily
Ga0080559_RS15015	COG1217	gtp-binding protein TYPA
Ga0080559_RS15020	COG2076	Multidrug Resistance protein
Ga0080559_RS15030	COG0840	transmembrane signaling receptor activity
Ga0080559_RS15040	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Ga0080559_RS15050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Ga0080559_RS15060	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Ga0080559_RS15065	COG2010	Cytochrome c
Ga0080559_RS15080	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Ga0080559_RS15085	COG2867	negative regulation of translational initiation
Ga0080559_RS15090	COG1546	Belongs to the CinA family
Ga0080559_RS15100	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Ga0080559_RS15100	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Ga0080559_RS15105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Ga0080559_RS15110	COG3852	Histidine kinase
Ga0080559_RS15115	COG2204	response regulator
Ga0080559_RS15120	COG5000	phosphorelay sensor kinase activity
Ga0080559_RS15125	COG2204	response regulator
Ga0080559_RS15135	COG0569	domain protein
Ga0080559_RS15140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Ga0080559_RS15145	COG1923	regulation of RNA biosynthetic process
Ga0080559_RS15150	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Ga0080559_RS15170	COG2084	Dehydrogenase
Ga0080559_RS15175	COG1764	response to oxidative stress
Ga0080559_RS15180	COG1530	ribonuclease E activity
Ga0080559_RS15185	COG0785	Cytochrome C biogenesis protein
Ga0080559_RS15200	COG3588	fructose-bisphosphate aldolase
Ga0080559_RS15215	COG0538	isocitrate dehydrogenase activity
Ga0080559_RS15225	COG0840	transmembrane signaling receptor activity
Ga0080559_RS15230	COG2814	Major facilitator Superfamily
Ga0080559_RS15250	COG0583	DNA-binding transcription factor activity
Ga0080559_RS15255	COG0583	DNA-binding transcription factor activity
Ga0080559_RS15275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080559_RS15280	COG1116	anion transmembrane transporter activity
Ga0080559_RS15285	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Ga0080559_RS15290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ga0080559_RS15295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Ga0080559_RS15305	COG2022	thiamine diphosphate biosynthetic process
Ga0080559_RS15325	COG1064	alcohol dehydrogenase
Ga0080559_RS15340	COG2186	Transcriptional regulator
Ga0080559_RS15345	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS15350	COG1129	ABC transporter
Ga0080559_RS15355	COG1879	ABC-type sugar transport system periplasmic component
Ga0080559_RS15365	COG4948	Mandelate Racemase Muconate Lactonizing
Ga0080559_RS15370	COG2814	Major facilitator Superfamily
Ga0080559_RS15375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080559_RS15390	COG1349	DNA-binding transcription factor activity
Ga0080559_RS15400	COG0647	UMP catabolic process
Ga0080559_RS15405	COG1846	Transcriptional regulator
Ga0080559_RS15425	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Ga0080559_RS15430	COG0804	urea catabolic process
Ga0080559_RS15435	COG0832	Belongs to the urease beta subunit family
Ga0080559_RS15435	COG0831	urea catabolic process
Ga0080559_RS15440	COG0830	nickel cation binding
Ga0080559_RS15470	COG0559	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS15485	COG0154	amidase activity
Ga0080559_RS15495	COG0183	Belongs to the thiolase family
Ga0080559_RS15505	COG1268	BioY protein
Ga0080559_RS15510	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Ga0080559_RS15515	COG1122	ATPase activity
Ga0080559_RS15520	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Ga0080559_RS15525	COG1845	cytochrome c oxidase, subunit III
Ga0080559_RS15530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Ga0080559_RS15535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Ga0080559_RS15540	COG0800	Aldolase
Ga0080559_RS15550	COG1414	Transcriptional regulator
Ga0080559_RS15555	COG1609	Transcriptional regulator
Ga0080559_RS15560	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Ga0080559_RS15570	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080559_RS15570	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Ga0080559_RS15575	COG0129	dihydroxy-acid dehydratase activity
Ga0080559_RS15580	COG2855	membrane
Ga0080559_RS15590	COG3181	Tripartite tricarboxylate transporter family receptor
Ga0080559_RS15595	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Ga0080559_RS15600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Ga0080559_RS15645	COG1653	transport
Ga0080559_RS15655	COG0395	ABC-type sugar transport system, permease component
Ga0080559_RS15660	COG3842	ATPase activity
Ga0080559_RS15690	COG4566	intracellular signal transduction
Ga0080559_RS15695	COG1366	Belongs to the anti-sigma-factor antagonist family
Ga0080559_RS15700	COG1366	Belongs to the anti-sigma-factor antagonist family
Ga0080559_RS15720	COG0446	pyridine nucleotide-disulphide oxidoreductase
Ga0080559_RS15720	COG1902	pentaerythritol trinitrate reductase activity
Ga0080559_RS15730	COG4948	Mandelate Racemase Muconate Lactonizing
Ga0080559_RS15735	COG0583	DNA-binding transcription factor activity
Ga0080559_RS15755	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080559_RS15760	COG1177	transmembrane transport
Ga0080559_RS15765	COG3842	ATPase activity
Ga0080559_RS15775	COG1335	isochorismatase
Ga0080559_RS15780	COG0402	S-adenosylhomocysteine deaminase activity
Ga0080559_RS15800	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080559_RS15820	COG1129	ABC transporter
Ga0080559_RS15825	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS15830	COG1879	ABC-type sugar transport system periplasmic component
Ga0080559_RS15835	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS15840	COG2376	Dihydroxyacetone kinase
Ga0080559_RS15845	COG1461	Dihydroxyacetone kinase
Ga0080559_RS15850	COG2376	Dihydroxyacetone kinase
Ga0080559_RS15855	COG0006	proline dipeptidase activity
Ga0080559_RS15860	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080559_RS15870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080559_RS15875	COG0601	transmembrane transport
Ga0080559_RS15880	COG0747	negative chemotaxis
Ga0080559_RS15885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ga0080559_RS15890	COG2188	Transcriptional regulator
Ga0080559_RS15920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Ga0080559_RS15935	COG0024	Methionine aminopeptidase
Ga0080559_RS15975	COG0747	negative chemotaxis
Ga0080559_RS15985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080559_RS15995	COG4608	Belongs to the ABC transporter superfamily
Ga0080559_RS16015	COG0583	DNA-binding transcription factor activity
Ga0080559_RS16020	COG1053	succinate dehydrogenase
Ga0080559_RS16025	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Ga0080559_RS16035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ga0080559_RS16065	COG0006	proline dipeptidase activity
Ga0080559_RS16090	COG1129	ABC transporter
Ga0080559_RS16095	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS16100	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS16115	COG0235	Class ii aldolase
Ga0080559_RS16120	COG3395	kinase activity
Ga0080559_RS16125	COG3622	Belongs to the hyi family
Ga0080559_RS16135	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Ga0080559_RS16140	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080559_RS16165	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS16170	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS16175	COG1129	ABC transporter
Ga0080559_RS16180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Ga0080559_RS16185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Ga0080559_RS16190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Ga0080559_RS16210	COG1454	alcohol dehydrogenase
Ga0080559_RS16220	COG2186	Transcriptional regulator
Ga0080559_RS16230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Ga0080559_RS16235	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Ga0080559_RS16240	COG2116	formate transmembrane transporter activity
Ga0080559_RS16245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ga0080559_RS16255	COG1024	Enoyl-CoA hydratase
Ga0080559_RS16255	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080559_RS16260	COG1960	acyl-CoA dehydrogenase activity
Ga0080559_RS16265	COG0438	transferase activity, transferring glycosyl groups
Ga0080559_RS16270	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Ga0080559_RS16285	COG0583	DNA-binding transcription factor activity
Ga0080559_RS16295	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Ga0080559_RS16335	COG1238	metal cluster binding
Ga0080559_RS16350	COG0010	Belongs to the arginase family
Ga0080559_RS16355	COG0517	IMP dehydrogenase activity
Ga0080559_RS16355	COG0516	GMP reductase activity
Ga0080559_RS16375	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Ga0080559_RS16380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Ga0080559_RS16400	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Ga0080559_RS16420	COG0114	fumarate hydratase activity
Ga0080559_RS16430	COG2059	Chromate
Ga0080559_RS16445	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Ga0080559_RS16450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Ga0080559_RS16460	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Ga0080559_RS16470	COG2166	iron-sulfur cluster assembly
Ga0080559_RS16485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080559_RS16505	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Ga0080559_RS16510	COG3263	regulation of cellular component size
Ga0080559_RS16515	COG0018	arginyl-trna synthetase
Ga0080559_RS16530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Ga0080559_RS16535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Ga0080559_RS16545	COG0717	Belongs to the dCTP deaminase family
Ga0080559_RS16560	COG0776	regulation of translation
Ga0080559_RS16565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Ga0080559_RS16570	COG0416	fatty acid biosynthetic process
Ga0080559_RS16575	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Ga0080559_RS16630	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Ga0080559_RS16670	COG4536	flavin adenine dinucleotide binding
Ga0080559_RS16675	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS16685	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Ga0080559_RS16690	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Ga0080559_RS16695	COG1091	dTDP-4-dehydrorhamnose reductase activity
Ga0080559_RS16705	COG0601	transmembrane transport
Ga0080559_RS16710	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080559_RS16715	COG4172	Belongs to the ABC transporter superfamily
Ga0080559_RS16735	COG4221	oxidoreductase activity
Ga0080559_RS16740	COG2272	Belongs to the type-B carboxylesterase lipase family
Ga0080559_RS16750	COG1309	transcriptional regulator
Ga0080559_RS16755	COG2207	Transcriptional regulator
Ga0080559_RS16760	COG0673	inositol 2-dehydrogenase activity
Ga0080559_RS16780	COG3547	Transposase (IS116 IS110 IS902 family)
Ga0080559_RS16805	COG0583	DNA-binding transcription factor activity
Ga0080559_RS16810	COG3842	ATPase activity
Ga0080559_RS16820	COG1177	transmembrane transport
Ga0080559_RS16830	COG1960	acyl-CoA dehydrogenase activity
Ga0080559_RS16840	COG1024	Enoyl-CoA hydratase
Ga0080559_RS16845	COG3246	L-lysine catabolic process to acetate
Ga0080559_RS16850	COG0824	Thioesterase
Ga0080559_RS16850	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080559_RS16855	COG0235	Class ii aldolase
Ga0080559_RS16880	COG2205	protein histidine kinase activity
Ga0080559_RS16890	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Ga0080559_RS16895	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Ga0080559_RS16905	COG0047	phosphoribosylformylglycinamidine synthase activity
Ga0080559_RS16915	COG2204	response regulator
Ga0080559_RS16930	COG1309	transcriptional regulator
Ga0080559_RS16980	COG0544	peptidyl-prolyl cis-trans isomerase activity
Ga0080559_RS16990	COG0359	binds to the 23S rRNA
Ga0080559_RS16995	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Ga0080559_RS17000	COG0360	Binds together with S18 to 16S ribosomal RNA
Ga0080559_RS17010	COG2353	YceI-like domain
Ga0080559_RS17015	COG2378	regulation of single-species biofilm formation
Ga0080559_RS17020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Ga0080559_RS17025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Ga0080559_RS17030	COG0805	protein transport
Ga0080559_RS17050	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Ga0080559_RS17070	COG1450	Type ii and iii secretion system protein
Ga0080559_RS17095	COG2165	general secretion pathway protein
Ga0080559_RS17110	COG1459	type II secretion system
Ga0080559_RS17115	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Ga0080559_RS17135	COG2832	Protein of unknown function (DUF454)
Ga0080559_RS17150	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
Ga0080559_RS17160	COG1805	sodium ion transport
Ga0080559_RS17170	COG1477	protein flavinylation
Ga0080559_RS17185	COG0517	IMP dehydrogenase activity
Ga0080559_RS17185	COG0516	GMP reductase activity
Ga0080559_RS17190	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS17210	COG3842	ATPase activity
Ga0080559_RS17215	COG1176	ABC-type spermidine putrescine transport system, permease component I
Ga0080559_RS17270	COG1473	amidohydrolase
Ga0080559_RS17275	COG0583	DNA-binding transcription factor activity
Ga0080559_RS17285	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080559_RS17315	COG3743	rRNA binding
Ga0080559_RS17315	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Ga0080559_RS17320	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Ga0080559_RS17330	COG3108	Peptidase M15
Ga0080559_RS17340	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Ga0080559_RS17360	COG2354	Protein conserved in bacteria
Ga0080559_RS17365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Ga0080559_RS17395	COG0033	Phosphoglucomutase
Ga0080559_RS17410	COG0297	glycogen (starch) synthase activity
Ga0080559_RS17415	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Ga0080559_RS17420	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Ga0080559_RS17425	COG0058	SHG alpha-glucan phosphorylase activity
Ga0080559_RS17430	COG0837	glucose binding
Ga0080559_RS17435	COG2723	6-phospho-beta-galactosidase activity
Ga0080559_RS17440	COG1609	Transcriptional regulator
Ga0080559_RS17445	COG1653	transport
Ga0080559_RS17450	COG1175	transmembrane transport
Ga0080559_RS17455	COG0395	ABC-type sugar transport system, permease component
Ga0080559_RS17460	COG0366	Alpha amylase catalytic
Ga0080559_RS17465	COG3842	ATPase activity
Ga0080559_RS17480	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Ga0080559_RS17495	COG1024	Enoyl-CoA hydratase
Ga0080559_RS17510	COG1309	transcriptional regulator
Ga0080559_RS17515	COG2326	polyphosphate kinase activity
Ga0080559_RS17525	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Ga0080559_RS17540	COG0697	spore germination
Ga0080559_RS17550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Ga0080559_RS17550	COG0519	Catalyzes the synthesis of GMP from XMP
Ga0080559_RS17585	COG0800	Aldolase
Ga0080559_RS17590	COG1215	transferase activity, transferring glycosyl groups
Ga0080559_RS17605	COG0583	DNA-binding transcription factor activity
Ga0080559_RS17610	COG1278	Cold shock
Ga0080559_RS17615	COG1393	Belongs to the ArsC family
Ga0080559_RS17620	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Ga0080559_RS17630	COG0501	Belongs to the peptidase M48B family
Ga0080559_RS17635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Ga0080559_RS17640	COG5425	PFAM Usg family protein
Ga0080559_RS17655	COG5285	phytanoyl-CoA dioxygenase
Ga0080559_RS17665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Ga0080559_RS17685	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Ga0080559_RS17695	COG0436	Aminotransferase
Ga0080559_RS17705	COG0702	epimerase
Ga0080559_RS17710	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Ga0080559_RS17715	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Ga0080559_RS17720	COG0259	pyridoxamine-phosphate oxidase activity
Ga0080559_RS17725	COG1278	Cold shock
Ga0080559_RS17740	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Ga0080559_RS17750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ga0080559_RS17765	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS17795	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Ga0080559_RS17805	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Ga0080559_RS17815	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Ga0080559_RS17830	COG1561	YicC-like family, N-terminal region
Ga0080559_RS17835	COG0194	GDP metabolic process
Ga0080559_RS17845	COG5002	protein histidine kinase activity
Ga0080559_RS17860	COG0573	inorganic phosphate transmembrane transporter activity
Ga0080559_RS17870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Ga0080559_RS17875	COG0704	Plays a role in the regulation of phosphate uptake
Ga0080559_RS17880	COG0745	RESPONSE REGULATOR receiver
Ga0080559_RS17885	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Ga0080559_RS17885	COG3743	rRNA binding
Ga0080559_RS17890	COG0052	Belongs to the universal ribosomal protein uS2 family
Ga0080559_RS17895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Ga0080559_RS17905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Ga0080559_RS17925	COG1408	metallophosphoesterase
Ga0080559_RS17930	COG2133	pyrroloquinoline quinone binding
Ga0080559_RS17935	COG0583	DNA-binding transcription factor activity
Ga0080559_RS17940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Ga0080559_RS17945	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Ga0080559_RS17985	COG0656	L-ascorbic acid biosynthetic process
Ga0080559_RS17990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Ga0080559_RS17995	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
Ga0080559_RS18000	COG2080	2 iron, 2 sulfur cluster binding
Ga0080559_RS18005	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS18025	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Ga0080559_RS18030	COG0583	DNA-binding transcription factor activity
Ga0080559_RS18035	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS18040	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS18050	COG1063	alcohol dehydrogenase
Ga0080559_RS18065	COG1902	pentaerythritol trinitrate reductase activity
Ga0080559_RS18090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Ga0080559_RS18100	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS18130	COG1129	ABC transporter
Ga0080559_RS18145	COG1960	acyl-CoA dehydrogenase activity
Ga0080559_RS18150	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS18160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Ga0080559_RS18165	COG1024	Enoyl-CoA hydratase
Ga0080559_RS18170	COG3246	L-lysine catabolic process to acetate
Ga0080559_RS18175	COG0427	acetyl-CoA hydrolase
Ga0080559_RS18180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Ga0080559_RS18195	COG1063	alcohol dehydrogenase
Ga0080559_RS18215	COG1172	Belongs to the binding-protein-dependent transport system permease family
Ga0080559_RS18245	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080559_RS18295	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
Ga0080559_RS18320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Ga0080559_RS18345	COG0183	Belongs to the thiolase family
Ga0080559_RS18355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ga0080559_RS18360	COG2301	Belongs to the HpcH HpaI aldolase family
Ga0080559_RS18380	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS18400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Ga0080559_RS18405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Ga0080559_RS18425	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Ga0080559_RS18440	COG1024	Enoyl-CoA hydratase
Ga0080559_RS18440	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080559_RS18445	COG2188	Transcriptional regulator
Ga0080559_RS18450	COG0183	Belongs to the thiolase family
Ga0080559_RS18460	COG2313	pseudouridylate synthase activity
Ga0080559_RS18475	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Ga0080559_RS18485	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Ga0080559_RS18490	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Ga0080559_RS18500	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Ga0080559_RS18505	COG0750	zinc metalloprotease
Ga0080559_RS18510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Ga0080559_RS18520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Ga0080559_RS18525	COG0233	cytoplasmic translational termination
Ga0080559_RS18530	COG0569	domain protein
Ga0080559_RS18535	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Ga0080559_RS18540	COG0528	UMP kinase activity
Ga0080559_RS18545	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Ga0080559_RS18550	COG0747	negative chemotaxis
Ga0080559_RS18555	COG1858	cytochrome C peroxidase
Ga0080559_RS18560	COG1196	nuclear chromosome segregation
Ga0080559_RS18560	COG0739	heme binding
Ga0080559_RS18560	COG0741	lytic transglycosylase activity
Ga0080559_RS18565	COG0629	single-stranded DNA binding
Ga0080559_RS18570	COG0248	Ppx GppA phosphatase
Ga0080559_RS18580	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
Ga0080559_RS18585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Ga0080559_RS18595	COG0646	methionine synthase
Ga0080559_RS18595	COG1410	methionine synthase
Ga0080559_RS18610	COG5012	cobalamin binding
Ga0080559_RS18630	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Ga0080559_RS18635	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Ga0080559_RS18640	COG0134	indole-3-glycerol-phosphate synthase activity
Ga0080559_RS18645	COG0315	cyclic pyranopterin monophosphate synthase activity
Ga0080559_RS18650	COG0303	'Molybdopterin
Ga0080559_RS18655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Ga0080559_RS18660	COG2333	competence protein COMEC
Ga0080559_RS18660	COG0658	competence protein
Ga0080559_RS18665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Ga0080559_RS18675	COG1024	Enoyl-CoA hydratase
Ga0080559_RS18680	COG3088	subunit of a heme lyase
Ga0080559_RS18685	COG1138	Cytochrome C-type biogenesis protein
Ga0080559_RS18710	COG0166	Belongs to the GPI family
Ga0080559_RS18720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Ga0080559_RS18735	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Ga0080559_RS18745	COG2979	Protein of unknown function (DUF533)
Ga0080559_RS18755	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Ga0080559_RS18760	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
Ga0080559_RS18760	COG3264	Mechanosensitive ion channel
Ga0080559_RS18770	COG0494	nUDIX hydrolase
Ga0080559_RS18780	COG0415	Belongs to the DNA photolyase family
Ga0080559_RS18790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Ga0080559_RS18800	COG0604	alcohol dehydrogenase
Ga0080559_RS18810	COG2186	Transcriptional regulator
Ga0080559_RS18820	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Ga0080559_RS18830	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080559_RS18835	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Ga0080559_RS18875	COG0105	UTP biosynthetic process
Ga0080559_RS18880	COG0488	(ABC) transporter
Ga0080559_RS18885	COG2095	MarC family integral membrane protein
Ga0080559_RS18890	COG3577	Aspartyl protease
Ga0080559_RS18900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Ga0080559_RS18915	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Ga0080559_RS18920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Ga0080559_RS18925	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Ga0080559_RS18930	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Ga0080559_RS18940	COG2890	protein-(glutamine-N5) methyltransferase activity
Ga0080559_RS18945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Ga0080559_RS18955	COG0010	Belongs to the arginase family
Ga0080559_RS18960	COG1473	amidohydrolase
Ga0080559_RS18965	COG3956	TIGRFAM MazG family protein
Ga0080559_RS18970	COG1840	ABC-type Fe3 transport system, periplasmic component
Ga0080559_RS18975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Ga0080559_RS18985	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Ga0080559_RS18995	COG0418	dihydroorotase activity
Ga0080559_RS19000	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Ga0080559_RS19005	COG0305	Participates in initiation and elongation during chromosome replication
Ga0080559_RS19015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Ga0080559_RS19025	COG1127	ABC transporter
Ga0080559_RS19055	COG1294	oxidase, subunit
Ga0080559_RS19060	COG1271	oxidase subunit
Ga0080559_RS19065	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Ga0080559_RS19080	COG4221	oxidoreductase activity
Ga0080559_RS19085	COG0179	Fumarylacetoacetate (FAA) hydrolase
Ga0080559_RS19095	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS19100	COG0277	FAD linked oxidase domain protein
Ga0080559_RS19105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Ga0080559_RS19110	COG0012	GTP binding
Ga0080559_RS19115	COG0534	Mate efflux family protein
Ga0080559_RS19135	COG2326	polyphosphate kinase activity
Ga0080559_RS19140	COG0159	tryptophan synthase activity
Ga0080559_RS19165	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Ga0080559_RS19180	COG0803	Belongs to the bacterial solute-binding protein 9 family
Ga0080559_RS19185	COG1121	(ABC) transporter
Ga0080559_RS19190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Ga0080559_RS19195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Ga0080559_RS19205	COG2943	transferase activity, transferring hexosyl groups
Ga0080559_RS19210	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
Ga0080559_RS19220	COG4251	negative regulation of phosphorylation
Ga0080559_RS19230	COG1335	isochorismatase
Ga0080559_RS19250	COG0628	permease
Ga0080559_RS19260	COG0193	aminoacyl-tRNA hydrolase activity
Ga0080559_RS19295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Ga0080559_RS19300	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Ga0080559_RS19305	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Ga0080559_RS19325	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Ga0080559_RS19335	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Ga0080559_RS19340	COG1612	heme a metabolic process
Ga0080559_RS19380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Ga0080559_RS19385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Ga0080559_RS19390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Ga0080559_RS19415	COG2151	metal-sulfur cluster biosynthetic enzyme
Ga0080559_RS19425	COG0110	maltose O-acetyltransferase activity
Ga0080559_RS19430	COG0316	Belongs to the HesB IscA family
Ga0080559_RS19435	COG0149	triose-phosphate isomerase activity
Ga0080559_RS19445	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080559_RS19450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Ga0080559_RS19455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Ga0080559_RS19460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Ga0080559_RS19485	COG1522	sequence-specific DNA binding
Ga0080559_RS19490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Ga0080559_RS19490	COG1648	precorrin-2 dehydrogenase activity
Ga0080559_RS19500	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Ga0080559_RS19505	COG0175	sulfate reduction
Ga0080559_RS19525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Ga0080559_RS19535	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Ga0080559_RS19540	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Ga0080559_RS19545	COG0546	phosphoglycolate phosphatase activity
Ga0080559_RS19550	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Ga0080559_RS19570	COG0488	(ABC) transporter
Ga0080559_RS19575	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Ga0080559_RS19580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Ga0080559_RS19600	COG0126	phosphoglycerate kinase activity
Ga0080559_RS19605	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Ga0080559_RS19610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Ga0080559_RS19620	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Ga0080559_RS19625	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Ga0080559_RS19630	COG4133	protoheme IX ABC transporter activity
Ga0080559_RS19635	COG3737	Protein of unknown function (DUF498/DUF598)
Ga0080559_RS19645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Ga0080559_RS19650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Ga0080559_RS19655	COG1862	Preprotein translocase
Ga0080559_RS19660	COG3591	Belongs to the peptidase S1B family
Ga0080559_RS19665	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Ga0080559_RS19680	COG1160	GTP binding
Ga0080559_RS19685	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Ga0080559_RS19695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Ga0080559_RS19700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Ga0080559_RS19710	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Ga0080559_RS19725	COG0482	sulfurtransferase activity
Ga0080559_RS19730	COG4335	DNA alkylation repair
Ga0080559_RS19735	COG1028	Short-chain dehydrogenase reductase Sdr
Ga0080559_RS19750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Ga0080559_RS19755	COG0243	molybdopterin cofactor binding
Ga0080559_RS19760	COG2146	nitrite reductase [NAD(P)H] activity
Ga0080559_RS19765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Ga0080559_RS19770	COG1116	anion transmembrane transporter activity
Ga0080559_RS19775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Ga0080559_RS19780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ga0080559_RS19780	COG1116	anion transmembrane transporter activity
Ga0080559_RS19785	COG1116	anion transmembrane transporter activity
Ga0080559_RS19785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Ga0080559_RS19790	COG3707	response regulator
Ga0080559_RS19805	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Ga0080559_RS19820	COG2885	chlorophyll binding
Ga0080559_RS19845	COG1994	Peptidase M50
Ga0080559_RS19845	COG0517	IMP dehydrogenase activity
Ga0080559_RS19935	COG0668	transmembrane transport
Ga0080559_RS19970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Ga0080559_RS20000	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Ga0080559_RS20045	COG4993	Dehydrogenase
Ga0080559_RS20050	COG0438	transferase activity, transferring glycosyl groups
Ga0080559_RS20055	COG1215	transferase activity, transferring glycosyl groups
Ga0080559_RS20060	COG1216	Glycosyl transferase, family 2
Ga0080559_RS20080	COG2197	response regulator
Ga0080559_RS20100	COG3685	Protein conserved in bacteria
Ga0080559_RS20130	COG1175	transmembrane transport
Ga0080559_RS20150	COG1070	Carbohydrate kinase
Ga0080559_RS20195	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Ga0080559_RS20215	COG0784	Response regulator, receiver
Ga0080559_RS20245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ga0080559_RS20250	COG0563	adenylate kinase activity
Ga0080559_RS20260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Ga0080559_RS20275	COG5002	protein histidine kinase activity
Ga0080559_RS20275	COG2176	DNA-directed DNA polymerase activity
Ga0080559_RS20280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Ga0080559_RS20285	COG2358	TRAP transporter, solute receptor (TAXI family
Ga0080559_RS20315	COG0589	response to stress
Ga0080559_RS20320	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Ga0080559_RS20325	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Ga0080559_RS20330	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Ga0080559_RS20335	COG1522	sequence-specific DNA binding
Ga0080559_RS20340	COG1012	belongs to the aldehyde dehydrogenase family
Ga0080559_RS20345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Ga0080559_RS20365	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS20370	COG2814	Major facilitator Superfamily
Ga0080559_RS20390	COG1268	BioY protein
Ga0080559_RS20395	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Ga0080559_RS20405	COG0505	Belongs to the CarA family
Ga0080559_RS20415	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS20420	COG0582	viral genome integration into host DNA
Ga0080559_RS20425	COG4974	Belongs to the 'phage' integrase family
Ga0080559_RS20430	COG3547	Transposase (IS116 IS110 IS902 family)
Ga0080559_RS20440	COG2258	MOSC domain
Ga0080559_RS20445	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
Ga0080559_RS20450	COG0210	DNA helicase
Ga0080559_RS20470	COG0662	Cupin 2, conserved barrel domain protein
Ga0080559_RS20475	COG2271	Major facilitator Superfamily
Ga0080559_RS20480	COG1881	PFAM PEBP family protein
Ga0080559_RS20520	COG0583	DNA-binding transcription factor activity
Ga0080559_RS20540	COG1280	lysine exporter protein (LysE YggA)
Ga0080559_RS20550	COG1522	sequence-specific DNA binding
Ga0080559_RS20555	COG1280	lysine exporter protein (LysE YggA)
Ga0080559_RS20565	COG2226	methyltransferase
Ga0080559_RS20590	COG0463	Glycosyl transferase, family 2
Ga0080559_RS20600	COG0753	catalase activity
Ga0080559_RS20620	COG0500	methyltransferase
Ga0080559_RS20630	COG0484	heat shock protein binding
Ga0080559_RS20635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Ga0080559_RS20675	COG0071	Belongs to the small heat shock protein (HSP20) family
Ga0080559_RS20705	COG0542	response to heat
Ga0080559_RS20715	COG0501	Belongs to the peptidase M48B family
Ga0080559_RS20725	COG0071	Belongs to the small heat shock protein (HSP20) family
Ga0080559_RS20730	COG0071	Belongs to the small heat shock protein (HSP20) family
Ga0080559_RS20735	COG0583	DNA-binding transcription factor activity
Ga0080559_RS20745	COG2948	multi-organism process
Ga0080559_RS20760	COG3846	protein secretion by the type IV secretion system
Ga0080559_RS20775	COG3451	type IV secretory pathway VirB4
Ga0080559_RS20800	COG4962	Type ii secretion system protein e
Ga0080559_RS20805	COG1321	iron dependent repressor
Ga0080559_RS20810	COG1914	H( )-stimulated, divalent metal cation uptake system
Ga0080559_RS20830	COG0741	lytic transglycosylase activity
Ga0080559_RS20880	COG5489	Protein of unknown function (DUF736)
Ga0080559_RS20915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Ga0080559_RS20920	COG1111	helicase
Ga0080559_RS20920	COG1205	dead DEAH box helicase
Ga0080559_RS21020	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Ga0080559_RS21035	COG0719	Fe-S assembly protein
Ga0080559_RS21040	COG0396	ATPase activity
Ga0080559_RS21050	COG0393	Putative heavy-metal-binding
Ga0080559_RS21060	COG0719	Fe-S assembly protein
Ga0080559_RS21070	COG1959	2 iron, 2 sulfur cluster binding
Ga0080559_RS21075	COG2945	thiolester hydrolase activity
Ga0080559_RS21090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Ga0080559_RS21115	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Ga0080559_RS21125	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Ga0080559_RS21130	COG2833	Protein of unknown function (DUF455)
Ga0080559_RS21135	COG0739	heme binding
Ga0080559_RS21145	COG0730	response to heat
Ga0080559_RS21150	COG1802	Transcriptional regulator
Ga0080559_RS21155	COG0405	Gamma-glutamyltransferase
Ga0080559_RS21160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Ga0080559_RS21165	COG1902	pentaerythritol trinitrate reductase activity
Ga0080559_RS21170	COG0343	queuine tRNA-ribosyltransferase activity
Ga0080559_RS21190	COG0513	Belongs to the DEAD box helicase family
Ga0080559_RS21205	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Ga0080559_RS21215	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Ga0080559_RS21215	COG3008	intermembrane lipid transfer
Ga0080559_RS21220	COG2995	paraquat-inducible protein a
Ga0080559_RS21235	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Ga0080559_RS21245	COG1007	ATP synthesis coupled electron transport
Ga0080559_RS21260	COG0713	ATP synthesis coupled electron transport
Ga0080559_RS21280	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Ga0080559_RS21285	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Ga0080559_RS21340	COG0649	NAD binding
Ga0080559_RS21345	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Ga0080559_RS21350	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Ga0080559_RS21365	COG1024	Enoyl-CoA hydratase
Ga0080559_RS21365	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ga0080559_RS21375	COG0625	glutathione transferase activity
Ga0080559_RS21390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Ga0080559_RS21395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ga0080559_RS21405	COG3047	cAMP biosynthetic process
Ga0080559_RS21410	COG1960	acyl-CoA dehydrogenase activity
Ga0080559_RS21445	COG3842	ATPase activity
Ga0080559_RS21460	COG0129	dihydroxy-acid dehydratase activity
Ga0080559_RS21475	COG0523	cobalamin synthesis protein
Ga0080559_RS21480	COG3443	Belongs to the bacterial solute-binding protein 9 family
Ga0080559_RS21530	COG2099	Precorrin-6x reductase
Ga0080559_RS21545	COG2875	Belongs to the precorrin methyltransferase family
Ga0080559_RS21550	COG1797	cobyrinic acid a,c-diamide synthase activity
Ga0080559_RS21555	COG1648	precorrin-2 dehydrogenase activity
Ga0080559_RS21555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Ga0080559_RS21635	COG0596	Alpha beta hydrolase
Ga0080559_RS21640	COG0583	DNA-binding transcription factor activity
Ga0080559_RS21645	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Ga0080559_RS21655	COG1254	Belongs to the acylphosphatase family
Ga0080559_RS21660	COG0481	GTPase activity
Ga0080559_RS21675	COG0187	DNA topoisomerase II activity
Ga0080559_RS21730	COG0456	acetyltransferase
Ga0080559_RS21735	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Ga0080559_RS21740	COG1917	Cupin 2, conserved barrel domain protein
Ga0080559_RS21745	COG0527	aspartate kinase activity
Ga0080559_RS21750	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Ga0080559_RS21770	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Ga0080559_RS21770	COG0446	pyridine nucleotide-disulphide oxidoreductase
Ga0080559_RS21775	COG4311	Sarcosine oxidase, delta subunit
Ga0080559_RS21780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ga0080559_RS21790	COG0069	glutamate synthase activity
Ga0080559_RS21795	COG2218	PFAM glutamate synthase alpha subunit domain protein
Ga0080559_RS21800	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Ga0080559_RS21805	COG1953	Uracil, thiamine, allantoin
Ga0080559_RS21815	COG1454	alcohol dehydrogenase
Ga0080559_RS21830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Ga0080559_RS21850	COG0004	ammonium transporteR
Ga0080559_RS21855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Ga0080559_RS21875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Ga0080559_RS21880	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Ga0080559_RS21885	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Ga0080559_RS21890	COG3454	Phosphonate metabolism
Ga0080559_RS21910	COG0747	negative chemotaxis
Ga0080559_RS21915	COG0601	transmembrane transport
Ga0080559_RS21920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ga0080559_RS21925	COG0444	Belongs to the ABC transporter superfamily
Ga0080559_RS21930	COG4608	Belongs to the ABC transporter superfamily
Ga0080559_RS21935	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Ga0080559_RS21940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Ga0080559_RS21975	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Ga0080559_RS21985	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Ga0080559_RS21990	COG0849	cell division
Ga0080559_RS21995	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Ga0080559_RS22000	COG1181	Belongs to the D-alanine--D-alanine ligase family
Ga0080559_RS22005	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Ga0080559_RS22015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Ga0080559_RS22020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Ga0080559_RS22035	COG2081	HI0933 family
Ga0080559_RS22045	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Ga0080559_RS22050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Ga0080559_RS22060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Ga0080559_RS22075	COG0275	rRNA processing
Ga0080559_RS22080	COG2001	Belongs to the MraZ family
Ga0080559_RS22460	COG1570	exodeoxyribonuclease VII activity
Ga0080559_RS22625	COG0840	transmembrane signaling receptor activity
Ga0080559_RS22935	COG0667	Aldo Keto reductase
Ga0080559_RS23095	COG3800	Transcriptional regulator
Ga0080559_RS23095	COG1396	sequence-specific DNA binding
Ga0080559_RS23635	COG0217	transcriptional regulatory protein
Ga0080559_RS23760	COG0022	dehydrogenase e1 component
Ga0080559_RS23760	COG0508	dehydrogenase complex catalyzes the overall conversion of
Ga0080559_RS24380	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Ga0080559_RS24460	COG0402	S-adenosylhomocysteine deaminase activity
Ga0080559_RS24465	COG0402	S-adenosylhomocysteine deaminase activity
Ga0080559_RS25080	COG1760	l-serine dehydratase
Ga0080559_RS25100	COG2814	Major facilitator Superfamily
Ga0080559_RS25110	COG1045	serine acetyltransferase
Ga0080559_RS25680	COG0402	S-adenosylhomocysteine deaminase activity
Ga0080559_RS25815	COG1876	peptidase activity