locus-tag	class	description
TBH_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TBH_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TBH_RS00020	COG0187	DNA topoisomerase II activity
TBH_RS00045	COG0752	glycyl-tRNA synthetase alpha subunit
TBH_RS00050	COG0439	Biotin carboxylase
TBH_RS00055	COG0511	ligase activity, forming carbon-carbon bonds
TBH_RS00060	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TBH_RS00065	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TBH_RS00070	COG4232	protein-disulfide reductase activity
TBH_RS00075	COG1324	tolerance protein
TBH_RS00085	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TBH_RS00120	COG0275	rRNA processing
TBH_RS00150	COG0330	HflC and HflK could
TBH_RS00155	COG0037	tRNA processing
TBH_RS00170	COG1368	sulfuric ester hydrolase activity
TBH_RS00185	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TBH_RS00190	COG3909	cytochrome
TBH_RS00205	COG2813	Specifically methylates the guanine in position
TBH_RS00210	COG2081	HI0933 family
TBH_RS00215	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TBH_RS00220	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TBH_RS00225	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
TBH_RS00240	COG3001	Fructosamine kinase
TBH_RS00250	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TBH_RS00260	COG0018	arginyl-trna synthetase
TBH_RS00285	COG0546	phosphoglycolate phosphatase activity
TBH_RS00300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TBH_RS00305	COG0134	indole-3-glycerol-phosphate synthase activity
TBH_RS00315	COG1765	OsmC-like protein
TBH_RS00325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
TBH_RS00330	COG2967	ApaG domain
TBH_RS00340	COG4206	TonB-dependent receptor
TBH_RS00350	COG0811	peptide transport
TBH_RS00355	COG0811	peptide transport
TBH_RS00360	COG0848	biopolymer transport protein
TBH_RS00400	COG0151	Belongs to the GarS family
TBH_RS00405	COG0138	bifunctional purine biosynthesis protein purh
TBH_RS00410	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
TBH_RS00425	COG2264	protein methyltransferase activity
TBH_RS00430	COG3118	belongs to the thioredoxin family
TBH_RS00435	COG0181	hydroxymethylbilane synthase activity
TBH_RS00445	COG1301	dicarboxylic acid transport
TBH_RS00465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
TBH_RS00465	COG0678	peroxiredoxin activity
TBH_RS00470	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
TBH_RS00480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
TBH_RS00525	COG0315	cyclic pyranopterin monophosphate synthase activity
TBH_RS00535	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
TBH_RS00540	COG0450	alkyl hydroperoxide reductase
TBH_RS00550	COG0205	6-phosphofructokinase activity
TBH_RS00595	COG2192	nodulation
TBH_RS00600	COG1088	dTDP-glucose 4,6-dehydratase activity
TBH_RS00620	COG1560	Kdo2-lipid A biosynthetic process
TBH_RS00625	COG1132	(ABC) transporter
TBH_RS00645	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TBH_RS00645	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TBH_RS00655	COG0667	Aldo Keto reductase
TBH_RS00660	COG1519	Transferase
TBH_RS00665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
TBH_RS00670	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
TBH_RS00680	COG0521	Mo-molybdopterin cofactor biosynthetic process
TBH_RS00685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TBH_RS00690	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
TBH_RS00695	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TBH_RS00700	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TBH_RS00710	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TBH_RS00715	COG3706	GGDEF domain
TBH_RS00720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TBH_RS00725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TBH_RS00730	COG0006	proline dipeptidase activity
TBH_RS00735	COG3079	Belongs to the UPF0149 family
TBH_RS00750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TBH_RS00765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TBH_RS00770	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TBH_RS00785	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TBH_RS00790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TBH_RS00805	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
TBH_RS00810	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TBH_RS00815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TBH_RS00825	COG0254	rRNA binding
TBH_RS00830	COG0281	malic enzyme
TBH_RS00835	COG0039	L-malate dehydrogenase activity
TBH_RS00875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TBH_RS00880	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TBH_RS00885	COG0069	glutamate synthase activity
TBH_RS00885	COG0070	glutamate synthase
TBH_RS00885	COG0067	glutamate synthase
TBH_RS00910	COG0312	modulator of DNA gyrase
TBH_RS00915	COG0312	modulator of DNA gyrase
TBH_RS00945	COG0697	spore germination
TBH_RS00955	COG0312	modulator of DNA gyrase
TBH_RS00960	COG0312	modulator of DNA gyrase
TBH_RS00965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TBH_RS00980	COG0424	maF-like protein
TBH_RS00985	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
TBH_RS00990	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
TBH_RS00995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TBH_RS00995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TBH_RS01005	COG0450	alkyl hydroperoxide reductase
TBH_RS01015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TBH_RS01025	COG0582	viral genome integration into host DNA
TBH_RS01045	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
TBH_RS01050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TBH_RS01055	COG0163	prenyltransferase activity
TBH_RS01065	COG0586	Pfam SNARE associated Golgi protein
TBH_RS01070	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TBH_RS01075	COG0352	thiamine-phosphate diphosphorylase activity
TBH_RS01110	COG1136	(ABC) transporter
TBH_RS01125	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
TBH_RS01130	COG0357	Ribosomal RNA small subunit methyltransferase G
TBH_RS01140	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
TBH_RS01145	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
TBH_RS01150	COG1192	Involved in chromosome partitioning
TBH_RS01155	COG1475	DNA binding
TBH_RS01165	COG0356	it plays a direct role in the translocation of protons across the membrane
TBH_RS01175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TBH_RS01180	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TBH_RS01185	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
TBH_RS01190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
TBH_RS01195	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
TBH_RS01200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
TBH_RS01205	COG1047	Peptidyl-prolyl cis-trans
TBH_RS01210	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TBH_RS01215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TBH_RS01245	COG0133	tryptophan synthase activity
TBH_RS01265	COG1011	Hydrolase
TBH_RS01275	COG0513	Belongs to the DEAD box helicase family
TBH_RS01290	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TBH_RS01295	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TBH_RS01315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TBH_RS01325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TBH_RS01330	COG0321	lipoyl(octanoyl) transferase activity
TBH_RS01345	COG1686	Belongs to the peptidase S11 family
TBH_RS01350	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TBH_RS01355	COG2951	lytic endotransglycosylase activity
TBH_RS01360	COG0772	Belongs to the SEDS family
TBH_RS01365	COG0768	penicillin binding
TBH_RS01370	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
TBH_RS01375	COG1792	Involved in formation and maintenance of cell shape
TBH_RS01380	COG1077	Cell shape determining protein MreB Mrl
TBH_RS01385	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TBH_RS01390	COG0154	amidase activity
TBH_RS01395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TBH_RS01400	COG4106	trans-aconitate 2-methyltransferase activity
TBH_RS01415	COG2813	Specifically methylates the guanine in position
TBH_RS01420	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TBH_RS01425	COG2890	protein-(glutamine-N5) methyltransferase activity
TBH_RS01430	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TBH_RS01435	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TBH_RS01455	COG2409	Drug exporters of the RND superfamily
TBH_RS01460	COG0193	aminoacyl-tRNA hydrolase activity
TBH_RS01465	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TBH_RS01470	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TBH_RS01510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TBH_RS01530	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TBH_RS01535	COG0081	regulation of translation
TBH_RS01540	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TBH_RS01545	COG0222	ribosome binding
TBH_RS01550	COG0085	RNA polymerase activity
TBH_RS01555	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TBH_RS01560	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
TBH_RS01565	COG0049	tRNA binding
TBH_RS01570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TBH_RS01575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TBH_RS01580	COG0051	transcription antitermination factor activity, RNA binding
TBH_RS01585	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TBH_RS01590	COG0088	Forms part of the polypeptide exit tunnel
TBH_RS01595	COG0089	rRNA binding
TBH_RS01600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TBH_RS01605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TBH_RS01610	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TBH_RS01615	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TBH_RS01620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TBH_RS01625	COG0255	Belongs to the universal ribosomal protein uL29 family
TBH_RS01630	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TBH_RS01635	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TBH_RS01640	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TBH_RS01645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TBH_RS01650	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TBH_RS01655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TBH_RS01660	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TBH_RS01665	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TBH_RS01670	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TBH_RS01675	COG1841	ribosomal large subunit assembly
TBH_RS01680	COG0200	Binds to the 23S rRNA
TBH_RS01685	COG0201	protein transport
TBH_RS01690	COG0257	Belongs to the bacterial ribosomal protein bL36 family
TBH_RS01695	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TBH_RS01700	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TBH_RS01705	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TBH_RS01710	COG0202	RNA polymerase activity
TBH_RS01715	COG0203	ribosomal protein L17
TBH_RS01730	COG3852	Histidine kinase
TBH_RS01735	COG2204	response regulator
TBH_RS01745	COG0426	domain, Protein
TBH_RS01745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TBH_RS01755	COG0167	dihydroorotate dehydrogenase activity
TBH_RS01760	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
TBH_RS01765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TBH_RS01770	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
TBH_RS01775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TBH_RS01780	COG0640	Transcriptional regulator
TBH_RS01785	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
TBH_RS01790	COG4942	peptidase
TBH_RS01795	COG0793	Belongs to the peptidase S41A family
TBH_RS01800	COG0693	protein deglycase activity
TBH_RS01810	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
TBH_RS01835	COG4585	Histidine kinase
TBH_RS01840	COG2197	response regulator
TBH_RS01850	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TBH_RS01855	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TBH_RS01865	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TBH_RS01865	COG1328	CTP reductase activity
TBH_RS01870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
TBH_RS01880	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
TBH_RS01885	COG4106	trans-aconitate 2-methyltransferase activity
TBH_RS01890	COG0019	diaminopimelate decarboxylase activity
TBH_RS01895	COG0400	carboxylic ester hydrolase activity
TBH_RS01925	COG1592	Rubrerythrin
TBH_RS01930	COG0564	pseudouridine synthase activity
TBH_RS01945	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TBH_RS01950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TBH_RS01995	COG0837	glucose binding
TBH_RS02000	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
TBH_RS02020	COG0629	single-stranded DNA binding
TBH_RS02025	COG2814	Major facilitator Superfamily
TBH_RS02035	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TBH_RS02040	COG2321	neutral zinc metallopeptidase
TBH_RS02045	COG0433	COG0433 Predicted ATPase
TBH_RS02050	COG0596	Alpha beta hydrolase
TBH_RS02055	COG1490	D-aminoacyl-tRNA deacylase activity
TBH_RS02080	COG2094	Belongs to the DNA glycosylase MPG family
TBH_RS02085	COG0408	coproporphyrinogen oxidase activity
TBH_RS02090	COG0009	L-threonylcarbamoyladenylate synthase
TBH_RS02100	COG2922	Belongs to the Smg family
TBH_RS02105	COG0758	DNA mediated transformation
TBH_RS02110	COG1652	LysM domain
TBH_RS02115	COG0242	peptide deformylase activity
TBH_RS02120	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TBH_RS02135	COG5000	phosphorelay sensor kinase activity
TBH_RS02140	COG2204	response regulator
TBH_RS02145	COG0569	domain protein
TBH_RS02150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TBH_RS02160	COG1666	GTP binding
TBH_RS02175	COG2363	Small membrane protein
TBH_RS02210	COG2239	Acts as a magnesium transporter
TBH_RS02215	COG1196	nuclear chromosome segregation
TBH_RS02215	COG0739	heme binding
TBH_RS02215	COG0741	lytic transglycosylase activity
TBH_RS02220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TBH_RS02225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TBH_RS02235	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
TBH_RS02255	COG1137	ATPase activity
TBH_RS02260	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
TBH_RS02270	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
TBH_RS02285	COG1127	ABC transporter
TBH_RS02290	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TBH_RS02295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
TBH_RS02300	COG2854	intermembrane phospholipid transfer
TBH_RS02310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TBH_RS02315	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TBH_RS02320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TBH_RS02325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TBH_RS02340	COG3647	Membrane
TBH_RS02345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TBH_RS02350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TBH_RS02355	COG0723	plastoquinol--plastocyanin reductase activity
TBH_RS02360	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TBH_RS02365	COG2857	Cytochrome c1
TBH_RS02370	COG0625	glutathione transferase activity
TBH_RS02375	COG2969	positive regulation of protein catabolic process
TBH_RS02390	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
TBH_RS02405	COG0390	transport system, permease component
TBH_RS02415	COG2920	part of a sulfur-relay system
TBH_RS02420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TBH_RS02425	COG2022	thiamine diphosphate biosynthetic process
TBH_RS02435	COG1022	Amp-dependent synthetase and ligase
TBH_RS02450	COG0004	ammonium transporteR
TBH_RS02455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TBH_RS02465	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
TBH_RS02470	COG1459	type II secretion system
TBH_RS02475	COG2165	general secretion pathway protein
TBH_RS02480	COG4970	Tfp pilus assembly protein FimT
TBH_RS02485	COG2165	general secretion pathway protein
TBH_RS02495	COG3156	type II secretion system protein K
TBH_RS02515	COG1450	Type ii and iii secretion system protein
TBH_RS02580	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
TBH_RS02580	COG2755	lipolytic protein G-D-S-L family
TBH_RS02595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TBH_RS02615	COG2863	cytochrome
TBH_RS02620	COG0210	DNA helicase
TBH_RS02625	COG1611	Belongs to the LOG family
TBH_RS02640	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TBH_RS02645	COG3005	denitrification pathway
TBH_RS02665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TBH_RS02670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TBH_RS02695	COG4133	protoheme IX ABC transporter activity
TBH_RS02705	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TBH_RS02715	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
TBH_RS02725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TBH_RS02745	COG0651	ATP synthesis coupled electron transport
TBH_RS02750	COG0650	Formate hydrogenlyase subunit 4
TBH_RS02760	COG0651	ATP synthesis coupled electron transport
TBH_RS02765	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
TBH_RS02765	COG3261	NADH dehydrogenase
TBH_RS02770	COG3260	NADH ubiquinone oxidoreductase 20
TBH_RS02775	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
TBH_RS02790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TBH_RS02795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TBH_RS02800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TBH_RS02805	COG3954	Phosphoribulokinase
TBH_RS02820	COG0277	FAD linked oxidase domain protein
TBH_RS02825	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
TBH_RS02830	COG0792	nuclease activity
TBH_RS02835	COG3107	peptidoglycan biosynthetic process
TBH_RS02840	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TBH_RS02845	COG2001	Belongs to the MraZ family
TBH_RS02850	COG0275	rRNA processing
TBH_RS02855	COG3116	cell division
TBH_RS02865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TBH_RS02870	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TBH_RS02875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TBH_RS02880	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TBH_RS02885	COG0772	Belongs to the SEDS family
TBH_RS02890	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TBH_RS02895	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TBH_RS02900	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TBH_RS02905	COG1181	Belongs to the D-alanine--D-alanine ligase family
TBH_RS02920	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
TBH_RS02925	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
TBH_RS02935	COG0739	heme binding
TBH_RS02940	COG0653	protein targeting
TBH_RS02945	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TBH_RS02950	COG0494	nUDIX hydrolase
TBH_RS02960	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
TBH_RS03005	COG0297	glycogen (starch) synthase activity
TBH_RS03015	COG0438	transferase activity, transferring glycosyl groups
TBH_RS03035	COG4969	Belongs to the N-Me-Phe pilin family
TBH_RS03075	COG2801	Transposase and inactivated derivatives
TBH_RS03100	COG2801	Transposase and inactivated derivatives
TBH_RS03120	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TBH_RS03125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TBH_RS03125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TBH_RS03135	COG1752	Esterase of the alpha-beta hydrolase superfamily
TBH_RS03160	COG5002	protein histidine kinase activity
TBH_RS03160	COG5001	Diguanylate cyclase
TBH_RS03165	COG1763	Mo-molybdopterin cofactor biosynthetic process
TBH_RS03170	COG0318	PFAM AMP-dependent synthetase and ligase
TBH_RS03185	COG4263	nitrous-oxide reductase activity
TBH_RS03215	COG0437	4 iron, 4 sulfur cluster binding
TBH_RS03220	COG0348	domain, Protein
TBH_RS03250	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
TBH_RS03255	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
TBH_RS03260	COG1575	Belongs to the MenA family. Type 1 subfamily
TBH_RS03265	COG0616	signal peptide processing
TBH_RS03275	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
TBH_RS03280	COG3422	double-strand break repair
TBH_RS03295	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TBH_RS03300	COG1940	carbohydrate kinase activity
TBH_RS03325	COG1192	Involved in chromosome partitioning
TBH_RS03350	COG3547	Transposase (IS116 IS110 IS902 family)
TBH_RS03355	COG1509	lysine 2,3-aminomutase activity
TBH_RS03360	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TBH_RS03370	COG0688	phosphatidylethanolamine metabolic process
TBH_RS03385	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TBH_RS03390	COG0343	queuine tRNA-ribosyltransferase activity
TBH_RS03400	COG1796	DNA polymerase
TBH_RS03400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TBH_RS03410	COG0494	nUDIX hydrolase
TBH_RS03420	COG1570	exodeoxyribonuclease VII activity
TBH_RS03430	COG0519	Catalyzes the synthesis of GMP from XMP
TBH_RS03430	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TBH_RS03445	COG0129	dihydroxy-acid dehydratase activity
TBH_RS03460	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TBH_RS03465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TBH_RS03495	COG0367	asparagine synthase
TBH_RS03520	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
TBH_RS03525	COG0534	Mate efflux family protein
TBH_RS03550	COG0243	molybdopterin cofactor binding
TBH_RS03555	COG0437	4 iron, 4 sulfur cluster binding
TBH_RS03560	COG3302	dmso reductase anchor subunit
TBH_RS03570	COG0588	phosphoglycerate mutase activity
TBH_RS03575	COG0826	peptidase U32
TBH_RS03590	COG0574	Belongs to the PEP-utilizing enzyme family
TBH_RS03590	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TBH_RS03605	COG0432	Pfam Uncharacterised protein family UPF0047
TBH_RS03630	COG2815	serine threonine protein kinase
TBH_RS03630	COG0515	serine threonine protein kinase
TBH_RS03635	COG0131	Imidazoleglycerol-phosphate dehydratase
TBH_RS03640	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TBH_RS03645	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TBH_RS03650	COG0107	imidazoleglycerol-phosphate synthase activity
TBH_RS03655	COG0140	phosphoribosyl-ATP diphosphatase activity
TBH_RS03660	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TBH_RS03665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TBH_RS03675	COG1331	Highly conserved protein containing a thioredoxin domain
TBH_RS03690	COG0544	peptidyl-prolyl cis-trans isomerase activity
TBH_RS03695	COG0740	serine-type endopeptidase activity
TBH_RS03700	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TBH_RS03705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TBH_RS03725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TBH_RS03740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TBH_RS03745	COG4464	protein tyrosine phosphatase activity
TBH_RS03755	COG0489	protein tyrosine kinase activity
TBH_RS03790	COG1132	(ABC) transporter
TBH_RS03795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TBH_RS03800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TBH_RS03810	COG2089	acid synthase
TBH_RS03815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TBH_RS03820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TBH_RS03825	COG1083	cytidylyl-transferase
TBH_RS03875	COG3436	PFAM IS66 Orf2 family protein
TBH_RS03880	COG4372	Transposase
TBH_RS03895	COG0297	glycogen (starch) synthase activity
TBH_RS03905	COG1434	Gram-negative-bacterium-type cell wall biogenesis
TBH_RS03955	COG0535	radical SAM domain protein
TBH_RS03965	COG4608	Belongs to the ABC transporter superfamily
TBH_RS03975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TBH_RS03980	COG0601	transmembrane transport
TBH_RS03985	COG0339	signal peptide processing
TBH_RS03990	COG4166	transmembrane transport
TBH_RS03995	COG1388	LysM domain
TBH_RS03995	COG0741	lytic transglycosylase activity
TBH_RS04010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TBH_RS04025	COG1858	cytochrome C peroxidase
TBH_RS04045	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
TBH_RS04055	COG0563	adenylate kinase activity
TBH_RS04080	COG0587	DNA-directed DNA polymerase activity
TBH_RS04105	COG1120	ATPase activity
TBH_RS04110	COG4139	cobalamin transport
TBH_RS04125	COG3547	Transposase (IS116 IS110 IS902 family)
TBH_RS04130	COG0494	nUDIX hydrolase
TBH_RS04135	COG0069	glutamate synthase activity
TBH_RS04140	COG0674	pyruvate-flavodoxin oxidoreductase activity
TBH_RS04140	COG1013	pyruvate-flavodoxin oxidoreductase activity
TBH_RS04140	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TBH_RS04140	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TBH_RS04145	COG0167	dihydroorotate dehydrogenase activity
TBH_RS04150	COG0210	DNA helicase
TBH_RS04160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TBH_RS04175	COG2801	Transposase and inactivated derivatives
TBH_RS04205	COG1528	Iron-storage protein
TBH_RS04220	COG0672	)-iron permease
TBH_RS04240	COG1272	protein, Hemolysin III
TBH_RS04265	COG2205	protein histidine kinase activity
TBH_RS04265	COG0745	RESPONSE REGULATOR receiver
TBH_RS04265	COG3292	Two component regulator propeller
TBH_RS04290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
TBH_RS04300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TBH_RS04305	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TBH_RS04310	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TBH_RS04310	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TBH_RS04330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TBH_RS04335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TBH_RS04345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
TBH_RS04360	COG3115	cell septum assembly
TBH_RS04365	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TBH_RS04370	COG0668	transmembrane transport
TBH_RS04375	COG2900	Belongs to the SlyX family
TBH_RS04380	COG0681	Belongs to the peptidase S26 family
TBH_RS04405	COG1968	undecaprenyl-diphosphatase activity
TBH_RS04415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TBH_RS04420	COG3028	Belongs to the UPF0307 family
TBH_RS04435	COG1053	succinate dehydrogenase
TBH_RS04440	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TBH_RS04445	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
TBH_RS04455	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
TBH_RS04470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TBH_RS04475	COG2197	response regulator
TBH_RS04480	COG1573	uracil-dna glycosylase
TBH_RS04485	COG0733	neurotransmitter:sodium symporter activity
TBH_RS04490	COG0322	excinuclease ABC activity
TBH_RS04520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TBH_RS04525	COG1131	(ABC) transporter
TBH_RS04545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TBH_RS04550	COG1127	ABC transporter
TBH_RS04565	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
TBH_RS04580	COG4657	Part of a membrane complex involved in electron transport
TBH_RS04585	COG4660	Part of a membrane complex involved in electron transport
TBH_RS04590	COG4659	FMN binding
TBH_RS04595	COG4658	electron transport chain
TBH_RS04600	COG4656	Part of a membrane complex involved in electron transport
TBH_RS04610	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TBH_RS04610	COG1013	pyruvate-flavodoxin oxidoreductase activity
TBH_RS04610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TBH_RS04610	COG0674	pyruvate-flavodoxin oxidoreductase activity
TBH_RS04615	COG2878	Part of a membrane complex involved in electron transport
TBH_RS04615	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
TBH_RS04620	COG0583	DNA-binding transcription factor activity
TBH_RS04630	COG0243	molybdopterin cofactor binding
TBH_RS04745	COG2267	carboxylic ester hydrolase activity
TBH_RS04750	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TBH_RS04755	COG1028	Short-chain dehydrogenase reductase Sdr
TBH_RS04765	COG3384	dioxygenase
TBH_RS04770	COG1802	Transcriptional regulator
TBH_RS04785	COG4569	acetaldehyde dehydrogenase (acetylating) activity
TBH_RS04825	COG1028	Short-chain dehydrogenase reductase Sdr
TBH_RS04830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TBH_RS04840	COG0277	FAD linked oxidase domain protein
TBH_RS05015	COG0629	single-stranded DNA binding
TBH_RS05035	COG0142	geranyltranstransferase activity
TBH_RS05040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TBH_RS05045	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TBH_RS05050	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TBH_RS05055	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TBH_RS05060	COG0730	response to heat
TBH_RS05085	COG0741	lytic transglycosylase activity
TBH_RS05095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
TBH_RS05100	COG4608	Belongs to the ABC transporter superfamily
TBH_RS05105	COG0444	Belongs to the ABC transporter superfamily
TBH_RS05110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TBH_RS05115	COG0601	transmembrane transport
TBH_RS05120	COG0747	negative chemotaxis
TBH_RS05125	COG0613	PHP domain protein
TBH_RS05130	COG0009	L-threonylcarbamoyladenylate synthase
TBH_RS05135	COG1994	Peptidase M50
TBH_RS05140	COG0180	Tryptophanyl-tRNA synthetase
TBH_RS05150	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TBH_RS05170	COG0729	surface antigen
TBH_RS05180	COG1160	GTP binding
TBH_RS05190	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TBH_RS05215	COG1842	Phage shock protein A
TBH_RS05225	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
TBH_RS05235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TBH_RS05245	COG2003	Belongs to the UPF0758 family
TBH_RS05250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TBH_RS05260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TBH_RS05280	COG0045	succinate-CoA ligase (ADP-forming) activity
TBH_RS05285	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
TBH_RS05290	COG0268	Binds directly to 16S ribosomal RNA
TBH_RS05300	COG0728	peptidoglycan biosynthetic process
TBH_RS05310	COG0196	riboflavin kinase activity
TBH_RS05315	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TBH_RS05320	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TBH_RS05325	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TBH_RS05345	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TBH_RS05360	COG0545	Peptidyl-prolyl cis-trans isomerase
TBH_RS05370	COG0564	pseudouridine synthase activity
TBH_RS05390	COG0242	peptide deformylase activity
TBH_RS05400	COG0542	response to heat
TBH_RS05410	COG0784	Response regulator, receiver
TBH_RS05410	COG2198	Histidine kinase
TBH_RS05410	COG2205	protein histidine kinase activity
TBH_RS05415	COG1024	Enoyl-CoA hydratase
TBH_RS05420	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
TBH_RS05425	COG0508	dehydrogenase complex catalyzes the overall conversion of
TBH_RS05430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TBH_RS05440	COG0596	Alpha beta hydrolase
TBH_RS05445	COG0708	Exodeoxyribonuclease III
TBH_RS05450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TBH_RS05460	COG0517	IMP dehydrogenase activity
TBH_RS05470	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TBH_RS05480	COG2204	response regulator
TBH_RS05485	COG3852	Histidine kinase
TBH_RS05515	COG0446	pyridine nucleotide-disulphide oxidoreductase
TBH_RS05525	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TBH_RS05535	COG1012	belongs to the aldehyde dehydrogenase family
TBH_RS05545	COG1047	Peptidyl-prolyl cis-trans
TBH_RS05555	COG2096	Adenosyltransferase
TBH_RS05560	COG4206	TonB-dependent receptor
TBH_RS05570	COG1959	2 iron, 2 sulfur cluster binding
TBH_RS05575	COG1104	cysteine desulfurase activity
TBH_RS05580	COG0822	iron-sulfur transferase activity
TBH_RS05585	COG0316	Belongs to the HesB IscA family
TBH_RS05590	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
TBH_RS05625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TBH_RS05635	COG3547	Transposase (IS116 IS110 IS902 family)
TBH_RS05640	COG1131	(ABC) transporter
TBH_RS05645	COG0842	Transport permease protein
TBH_RS05650	COG2270	Major facilitator Superfamily
TBH_RS05680	COG0306	phosphate transporter
TBH_RS05695	COG1566	PFAM secretion protein HlyD family protein
TBH_RS05705	COG0628	permease
TBH_RS05750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TBH_RS05765	COG1028	Short-chain dehydrogenase reductase Sdr
TBH_RS05795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TBH_RS05800	COG0481	GTPase activity
TBH_RS05820	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TBH_RS05825	COG1381	Involved in DNA repair and RecF pathway recombination
TBH_RS05830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
TBH_RS05845	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TBH_RS05850	COG2954	triphosphatase activity
TBH_RS05860	COG1472	Belongs to the glycosyl hydrolase 3 family
TBH_RS05865	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
TBH_RS05885	COG3693	PFAM glycoside hydrolase, family 10
TBH_RS05900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TBH_RS05915	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
TBH_RS05920	COG0024	Methionine aminopeptidase
TBH_RS05925	COG0052	Belongs to the universal ribosomal protein uS2 family
TBH_RS05930	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TBH_RS05935	COG0528	UMP kinase activity
TBH_RS05940	COG0233	cytoplasmic translational termination
TBH_RS05945	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TBH_RS05950	COG0575	Belongs to the CDS family
TBH_RS05955	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TBH_RS05980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TBH_RS05990	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TBH_RS05995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TBH_RS06005	COG0825	malonyl-CoA metabolic process
TBH_RS06010	COG0037	tRNA processing
TBH_RS06015	COG2995	paraquat-inducible protein a
TBH_RS06030	COG2205	protein histidine kinase activity
TBH_RS06030	COG5002	protein histidine kinase activity
TBH_RS06030	COG0784	Response regulator, receiver
TBH_RS06055	COG4771	TonB-dependent receptor
TBH_RS06075	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
TBH_RS06085	COG0557	exoribonuclease II activity
TBH_RS06100	COG1070	Carbohydrate kinase
TBH_RS06115	COG2015	COG2015, Alkyl sulfatase and related hydrolases
TBH_RS06135	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
TBH_RS06150	COG1469	GTP cyclohydrolase I activity
TBH_RS06155	COG0142	geranyltranstransferase activity
TBH_RS06170	COG0187	DNA topoisomerase II activity
TBH_RS06190	COG1862	Preprotein translocase
TBH_RS06195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TBH_RS06200	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TBH_RS06230	COG0714	Associated with various cellular activities
TBH_RS06235	COG0149	triose-phosphate isomerase activity
TBH_RS06250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TBH_RS06255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TBH_RS06260	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TBH_RS06265	COG0649	NAD binding
TBH_RS06270	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
TBH_RS06280	COG1034	ATP synthesis coupled electron transport
TBH_RS06285	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TBH_RS06290	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TBH_RS06300	COG0713	ATP synthesis coupled electron transport
TBH_RS06315	COG1007	ATP synthesis coupled electron transport
TBH_RS06355	COG2166	iron-sulfur cluster assembly
TBH_RS06360	COG0316	Belongs to the HesB IscA family
TBH_RS06365	COG2151	metal-sulfur cluster biosynthetic enzyme
TBH_RS06370	COG0719	Fe-S assembly protein
TBH_RS06375	COG0396	ATPase activity
TBH_RS06380	COG0719	Fe-S assembly protein
TBH_RS06405	COG1234	tRNA 3'-trailer cleavage
TBH_RS06430	COG2304	oxidoreductase activity
TBH_RS06435	COG3764	Sortase (surface protein transpeptidase)
TBH_RS06455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TBH_RS06475	COG0525	valine-tRNA ligase activity
TBH_RS06495	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TBH_RS06500	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
TBH_RS06505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TBH_RS06525	COG0789	Transcriptional regulator
TBH_RS06540	COG0418	dihydroorotase activity
TBH_RS06560	COG0471	metal ion transport
TBH_RS06560	COG3273	potassium ion transport
TBH_RS06565	COG0742	ribosomal rna small subunit methyltransferase
TBH_RS06575	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
TBH_RS06585	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TBH_RS06590	COG0066	3-isopropylmalate dehydratase activity
TBH_RS06595	COG1247	-acetyltransferase
TBH_RS06600	COG0473	3-isopropylmalate dehydrogenase activity
TBH_RS06620	COG0135	phosphoribosylanthranilate isomerase activity
TBH_RS06625	COG0133	tryptophan synthase activity
TBH_RS06630	COG0159	tryptophan synthase activity
TBH_RS06635	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TBH_RS06640	COG0285	dihydrofolate synthase activity
TBH_RS06650	COG1286	toxin biosynthetic process
TBH_RS06680	COG3228	Belongs to the MtfA family
TBH_RS06685	COG1674	ftsk spoiiie
TBH_RS06690	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
TBH_RS06695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TBH_RS06700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TBH_RS06710	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TBH_RS06730	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TBH_RS06740	COG0291	Belongs to the bacterial ribosomal protein bL35 family
TBH_RS06745	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TBH_RS06750	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TBH_RS06755	COG0072	phenylalanine-tRNA ligase activity
TBH_RS06760	COG0776	regulation of translation
TBH_RS06800	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TBH_RS06820	COG2379	hydroxypyruvate reductase
TBH_RS06825	COG2833	Protein of unknown function (DUF455)
TBH_RS06835	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TBH_RS06845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TBH_RS06850	COG0215	cysteine-tRNA ligase activity
TBH_RS06860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TBH_RS06865	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
TBH_RS06885	COG0438	transferase activity, transferring glycosyl groups
TBH_RS06940	COG0531	amino acid
TBH_RS06945	COG0531	amino acid
TBH_RS06970	COG1360	Flagellar Motor Protein
TBH_RS06975	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
TBH_RS07010	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
TBH_RS07020	COG4787	bacterial-type flagellum-dependent cell motility
TBH_RS07030	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
TBH_RS07035	COG1706	bacterial-type flagellum-dependent cell motility
TBH_RS07040	COG1705	Flagellar rod assembly protein muramidase FlgJ
TBH_RS07040	COG3951	Flagellar rod assembly protein muramidase FlgJ
TBH_RS07045	COG1256	bacterial-type flagellum assembly
TBH_RS07055	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TBH_RS07060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TBH_RS07065	COG1334	flagellar protein FlaG
TBH_RS07070	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
TBH_RS07100	COG1677	Flagellar hook-basal body complex protein FliE
TBH_RS07110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TBH_RS07185	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TBH_RS07235	COG0501	Belongs to the peptidase M48B family
TBH_RS07240	COG1704	LemA family
TBH_RS07250	COG1643	Atp-dependent helicase
TBH_RS07275	COG3012	SEC-C Motif Domain Protein
TBH_RS07280	COG1196	nuclear chromosome segregation
TBH_RS07280	COG0741	lytic transglycosylase activity
TBH_RS07280	COG0739	heme binding
TBH_RS07305	COG0326	Molecular chaperone. Has ATPase activity
TBH_RS07320	COG0563	adenylate kinase activity
TBH_RS07325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TBH_RS07335	COG1959	2 iron, 2 sulfur cluster binding
TBH_RS07340	COG1399	metal-binding, possibly nucleic acid-binding protein
TBH_RS07345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TBH_RS07350	COG0416	fatty acid biosynthetic process
TBH_RS07355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TBH_RS07360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TBH_RS07375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TBH_RS07380	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TBH_RS07385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TBH_RS07390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TBH_RS07395	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TBH_RS07410	COG0084	hydrolase, TatD family'
TBH_RS07455	COG2204	response regulator
TBH_RS07460	COG4191	Histidine kinase
TBH_RS07465	COG0672	)-iron permease
TBH_RS07505	COG2217	Heavy metal translocating P-type atpase
TBH_RS07525	COG1230	cation diffusion facilitator family transporter
TBH_RS07590	COG3706	GGDEF domain
TBH_RS07590	COG2203	Gaf domain
TBH_RS07590	COG4251	negative regulation of phosphorylation
TBH_RS07590	COG5001	Diguanylate cyclase
TBH_RS07595	COG2201	protein-glutamate methylesterase activity
TBH_RS07600	COG2198	Histidine kinase
TBH_RS07600	COG0784	Response regulator, receiver
TBH_RS07600	COG0643	Histidine kinase
TBH_RS07610	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
TBH_RS07620	COG0840	transmembrane signaling receptor activity
TBH_RS07625	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TBH_RS07630	COG4106	trans-aconitate 2-methyltransferase activity
TBH_RS07655	COG0556	nucleotide-excision repair
TBH_RS07660	COG0436	Aminotransferase
TBH_RS07695	COG0668	transmembrane transport
TBH_RS07705	COG2850	peptidyl-arginine hydroxylation
TBH_RS07720	COG2046	Belongs to the sulfate adenylyltransferase family
TBH_RS07735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TBH_RS07740	COG1518	maintenance of DNA repeat elements
TBH_RS07770	COG1857	crispr-associated protein
TBH_RS07785	COG1203	CRISPR-associated helicase, Cas3
TBH_RS07790	COG0284	orotidine-5'-phosphate decarboxylase activity
TBH_RS07795	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
TBH_RS07805	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
TBH_RS07810	COG0484	heat shock protein binding
TBH_RS07815	COG0443	Heat shock 70 kDa protein
TBH_RS07820	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TBH_RS07825	COG1420	regulation of RNA biosynthetic process
TBH_RS07830	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TBH_RS07835	COG0497	DNA recombination
TBH_RS07840	COG0735	belongs to the Fur family
TBH_RS07845	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TBH_RS07850	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
TBH_RS07855	COG0501	Belongs to the peptidase M48B family
TBH_RS07865	COG1162	GTPase activity
TBH_RS07905	COG0795	lipopolysaccharide-transporting ATPase activity
TBH_RS07910	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TBH_RS07920	COG3437	response regulator, receiver
TBH_RS07925	COG3437	response regulator, receiver
TBH_RS07925	COG4999	Histidine kinase
TBH_RS07925	COG3850	Histidine kinase
TBH_RS07925	COG2205	protein histidine kinase activity
TBH_RS07930	COG1185	polyribonucleotide nucleotidyltransferase activity
TBH_RS07935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TBH_RS07940	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TBH_RS07945	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TBH_RS07950	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TBH_RS07955	COG0195	Participates in both transcription termination and antitermination
TBH_RS07955	COG2251	uridine kinase activity
TBH_RS07960	COG0779	Required for maturation of 30S ribosomal subunits
TBH_RS07965	COG2914	Belongs to the UPF0125 (RnfH) family
TBH_RS07970	COG2867	negative regulation of translational initiation
TBH_RS07975	COG1115	amino acid carrier protein
TBH_RS07980	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TBH_RS07985	COG2326	polyphosphate kinase activity
TBH_RS08000	COG0546	phosphoglycolate phosphatase activity
TBH_RS08015	COG1530	ribonuclease E activity
TBH_RS08020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TBH_RS08025	COG2217	Heavy metal translocating P-type atpase
TBH_RS08045	COG2132	Multicopper oxidase
TBH_RS08085	COG0243	molybdopterin cofactor binding
TBH_RS08090	COG0437	4 iron, 4 sulfur cluster binding
TBH_RS08120	COG2835	tetraacyldisaccharide 4'-kinase activity
TBH_RS08125	COG1663	tetraacyldisaccharide 4'-kinase activity
TBH_RS08130	COG0848	biopolymer transport protein
TBH_RS08135	COG0811	peptide transport
TBH_RS08150	COG1136	(ABC) transporter
TBH_RS08155	COG4591	ABC-type transport system involved in lipoprotein release permease component
TBH_RS08210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
TBH_RS08245	COG0745	RESPONSE REGULATOR receiver
TBH_RS08250	COG5002	protein histidine kinase activity
TBH_RS08275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TBH_RS08280	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TBH_RS08295	COG0517	IMP dehydrogenase activity
TBH_RS08300	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TBH_RS08305	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TBH_RS08320	COG1214	PFAM Peptidase M22, glycoprotease
TBH_RS08335	COG0567	Dehydrogenase, E1 component
TBH_RS08340	COG0508	dehydrogenase complex catalyzes the overall conversion of
TBH_RS08375	COG0398	Pfam SNARE associated Golgi protein
TBH_RS08435	COG0436	Aminotransferase
TBH_RS08440	COG2171	N-acyltransferase activity
TBH_RS08445	COG1393	Belongs to the ArsC family
TBH_RS08455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TBH_RS08465	COG0537	adenosine 5'-monophosphoramidase activity
TBH_RS08470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TBH_RS08475	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TBH_RS08490	COG1752	Esterase of the alpha-beta hydrolase superfamily
TBH_RS08495	COG5016	pyruvate
TBH_RS08495	COG0511	ligase activity, forming carbon-carbon bonds
TBH_RS08500	COG0439	Biotin carboxylase
TBH_RS08505	COG2862	Uncharacterized protein family, UPF0114
TBH_RS08530	COG1309	transcriptional regulator
TBH_RS08545	COG1850	ribulose-bisphosphate carboxylase activity
TBH_RS08550	COG0583	DNA-binding transcription factor activity
TBH_RS08555	COG0084	hydrolase, TatD family'
TBH_RS08565	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TBH_RS08570	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
TBH_RS08575	COG0148	phosphopyruvate hydratase activity
TBH_RS08580	COG2877	3-deoxy-8-phosphooctulonate synthase activity
TBH_RS08585	COG0504	CTP synthase activity
TBH_RS08595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TBH_RS08600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TBH_RS08605	COG3278	Belongs to the heme-copper respiratory oxidase family
TBH_RS08620	COG2010	Cytochrome c
TBH_RS08635	COG2217	Heavy metal translocating P-type atpase
TBH_RS08645	COG0514	ATP-dependent DNA helicase (RecQ)
TBH_RS08675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TBH_RS08680	COG0488	(ABC) transporter
TBH_RS08685	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
TBH_RS08690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TBH_RS08710	COG1278	Cold shock
TBH_RS08730	COG0482	sulfurtransferase activity
TBH_RS08745	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TBH_RS08800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TBH_RS08805	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TBH_RS08815	COG0668	transmembrane transport
TBH_RS08825	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
TBH_RS08830	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
TBH_RS08835	COG0492	ferredoxin-NADP+ reductase activity
TBH_RS08840	COG0686	Belongs to the AlaDH PNT family
TBH_RS08845	COG0745	RESPONSE REGULATOR receiver
TBH_RS08850	COG0642	Histidine kinase
TBH_RS08855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TBH_RS08860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TBH_RS08870	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
TBH_RS08880	COG3547	Transposase (IS116 IS110 IS902 family)
TBH_RS08890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TBH_RS08895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TBH_RS08900	COG0505	Belongs to the CarA family
TBH_RS08905	COG3118	belongs to the thioredoxin family
TBH_RS08910	COG3118	belongs to the thioredoxin family
TBH_RS08915	COG1720	tRNA m6t6A37 methyltransferase activity
TBH_RS08940	COG1355	regulation of microtubule-based process
TBH_RS08955	COG0436	Aminotransferase
TBH_RS08970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TBH_RS08975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TBH_RS08980	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
TBH_RS08985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TBH_RS09005	COG2827	Endonuclease containing a URI domain
TBH_RS09010	COG0363	glucosamine-6-phosphate deaminase activity
TBH_RS09015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
TBH_RS09040	COG0183	Belongs to the thiolase family
TBH_RS09050	COG1022	Amp-dependent synthetase and ligase
TBH_RS09060	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TBH_RS09065	COG0542	response to heat
TBH_RS09070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
TBH_RS09080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TBH_RS09090	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
TBH_RS09115	COG0588	phosphoglycerate mutase activity
TBH_RS09120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TBH_RS09125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TBH_RS09130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
TBH_RS09135	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
TBH_RS09145	COG0586	Pfam SNARE associated Golgi protein
TBH_RS09150	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TBH_RS09160	COG0508	dehydrogenase complex catalyzes the overall conversion of
TBH_RS09195	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TBH_RS09200	COG3588	fructose-bisphosphate aldolase
TBH_RS09205	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TBH_RS09215	COG0589	response to stress
TBH_RS09245	COG0028	Belongs to the TPP enzyme family
TBH_RS09270	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TBH_RS09280	COG0436	Aminotransferase
TBH_RS09300	COG1280	lysine exporter protein (LysE YggA)
TBH_RS09320	COG4536	flavin adenine dinucleotide binding
TBH_RS09355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TBH_RS09360	COG0305	Participates in initiation and elongation during chromosome replication
TBH_RS09365	COG0359	binds to the 23S rRNA
TBH_RS09380	COG0360	Binds together with S18 to 16S ribosomal RNA
TBH_RS09385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TBH_RS09390	COG0557	exoribonuclease II activity
TBH_RS09405	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
TBH_RS09415	COG0463	Glycosyl transferase, family 2
TBH_RS09420	COG1881	PFAM PEBP family protein
TBH_RS09435	COG0456	acetyltransferase
TBH_RS09440	COG1573	uracil-dna glycosylase
TBH_RS09445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TBH_RS09455	COG1183	phosphatidylcholine synthase activity
TBH_RS09470	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TBH_RS09480	COG0028	Belongs to the TPP enzyme family
TBH_RS09495	COG2205	protein histidine kinase activity
TBH_RS09505	COG0745	RESPONSE REGULATOR receiver
TBH_RS09540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TBH_RS09565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TBH_RS09585	COG1283	sodium-dependent phosphate transmembrane transporter activity
TBH_RS09590	COG2925	Exonuclease
TBH_RS09600	COG0335	large ribosomal subunit rRNA binding
TBH_RS09605	COG0336	Belongs to the RNA methyltransferase TrmD family
TBH_RS09610	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TBH_RS09630	COG0076	glutamate decarboxylase activity
TBH_RS09645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TBH_RS09645	COG0189	ligase activity
TBH_RS09680	COG2304	oxidoreductase activity
TBH_RS09685	COG2304	oxidoreductase activity
TBH_RS09700	COG0714	Associated with various cellular activities
TBH_RS09705	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TBH_RS09715	COG0248	Ppx GppA phosphatase
TBH_RS09720	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
TBH_RS09740	COG2917	probably involved in intracellular septation
TBH_RS09745	COG2350	Protein conserved in bacteria
TBH_RS09750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TBH_RS09770	COG1238	metal cluster binding
TBH_RS09780	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TBH_RS09795	COG0585	pseudouridine synthase activity
TBH_RS09800	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TBH_RS09805	COG1160	GTP binding
TBH_RS09810	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TBH_RS09815	COG2976	Protein conserved in bacteria
TBH_RS09820	COG0124	histidyl-tRNA synthetase
TBH_RS09835	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TBH_RS09840	COG1505	serine-type exopeptidase activity
TBH_RS09845	COG0517	IMP dehydrogenase activity
TBH_RS09845	COG1994	Peptidase M50
TBH_RS09860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TBH_RS09875	COG3154	lipid carrier protein
TBH_RS09880	COG0826	peptidase U32
TBH_RS09885	COG0826	peptidase U32
TBH_RS09890	COG1242	4 iron, 4 sulfur cluster binding
TBH_RS09915	COG0612	Peptidase, M16
TBH_RS09935	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
TBH_RS09935	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
TBH_RS09945	COG0243	molybdopterin cofactor binding
TBH_RS09950	COG0437	4 iron, 4 sulfur cluster binding
TBH_RS09955	COG0348	domain, Protein
TBH_RS09970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
TBH_RS09970	COG3008	intermembrane lipid transfer
TBH_RS09975	COG2995	paraquat-inducible protein a
TBH_RS09980	COG2995	paraquat-inducible protein a
TBH_RS10000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TBH_RS10005	COG0302	gtp cyclohydrolase
TBH_RS10025	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
TBH_RS10035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TBH_RS10040	COG2137	regulation of response to DNA damage stimulus
TBH_RS10055	COG1546	Belongs to the CinA family
TBH_RS10070	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TBH_RS10080	COG0631	protein serine/threonine phosphatase activity
TBH_RS10085	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
TBH_RS10090	COG4974	Belongs to the 'phage' integrase family
TBH_RS10095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TBH_RS10105	COG2983	Belongs to the UPF0260 family
TBH_RS10110	COG4681	YaeQ
TBH_RS10120	COG1560	Kdo2-lipid A biosynthetic process
TBH_RS10140	COG4657	Part of a membrane complex involved in electron transport
TBH_RS10145	COG2878	Part of a membrane complex involved in electron transport
TBH_RS10155	COG4658	electron transport chain
TBH_RS10160	COG4659	FMN binding
TBH_RS10165	COG4660	Part of a membrane complex involved in electron transport
TBH_RS10170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TBH_RS10175	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TBH_RS10180	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TBH_RS10190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TBH_RS10195	COG1228	amidohydrolase
TBH_RS10215	COG0640	Transcriptional regulator
TBH_RS10220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TBH_RS10235	COG0701	Predicted permease
TBH_RS10250	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
TBH_RS10270	COG2608	mercury ion transmembrane transporter activity
TBH_RS10280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TBH_RS10290	COG1136	(ABC) transporter
TBH_RS10325	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TBH_RS10330	COG1230	cation diffusion facilitator family transporter
TBH_RS10360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TBH_RS10370	COG4372	Transposase
TBH_RS10375	COG3436	PFAM IS66 Orf2 family protein
TBH_RS10415	COG2015	COG2015, Alkyl sulfatase and related hydrolases
TBH_RS10435	COG0385	Bile acid
TBH_RS10445	COG0798	PFAM Bile acid sodium symporter
TBH_RS10495	COG0714	Associated with various cellular activities
TBH_RS10505	COG1074	ATP-dependent DNA helicase activity
TBH_RS10510	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
TBH_RS10520	COG0746	molybdenum cofactor guanylyltransferase activity
TBH_RS10530	COG0515	serine threonine protein kinase
TBH_RS10545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TBH_RS10550	COG1758	RNA polymerase activity
TBH_RS10560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
TBH_RS10565	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TBH_RS10570	COG0742	ribosomal rna small subunit methyltransferase
TBH_RS10575	COG0612	Peptidase, M16
TBH_RS10580	COG0612	Peptidase, M16
TBH_RS10585	COG0552	protein localization to endoplasmic reticulum
TBH_RS10590	COG2884	Cell division ATP-binding protein ftsE
TBH_RS10595	COG2177	Part of the ABC transporter FtsEX involved in
TBH_RS10600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TBH_RS10605	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
TBH_RS10620	COG0156	8-amino-7-oxononanoate synthase activity
TBH_RS10625	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TBH_RS10655	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TBH_RS10660	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TBH_RS10665	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TBH_RS10675	COG0828	Belongs to the bacterial ribosomal protein bS21 family
TBH_RS10680	COG1610	YqeY-like protein
TBH_RS10780	COG0489	protein tyrosine kinase activity
TBH_RS10785	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TBH_RS10785	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TBH_RS10795	COG1199	ATP-dependent helicase activity
TBH_RS10815	COG1131	(ABC) transporter
TBH_RS10820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
TBH_RS10825	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TBH_RS10830	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
TBH_RS10840	COG0330	HflC and HflK could
TBH_RS10845	COG0330	HflC and HflK could
TBH_RS10850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TBH_RS10860	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TBH_RS10865	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TBH_RS10870	COG0446	pyridine nucleotide-disulphide oxidoreductase
TBH_RS10875	COG2863	cytochrome
TBH_RS10885	COG0860	N-Acetylmuramoyl-L-alanine amidase
TBH_RS10890	COG0802	atpase or kinase
TBH_RS10895	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TBH_RS10895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TBH_RS10905	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
TBH_RS10910	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
TBH_RS10915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TBH_RS10920	COG2716	regulation of RNA biosynthetic process
TBH_RS10925	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TBH_RS10930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
TBH_RS10950	COG0776	regulation of translation
TBH_RS10955	COG0539	negative regulation of cytoplasmic translation
TBH_RS10960	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TBH_RS10965	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TBH_RS10970	COG0287	Prephenate dehydrogenase
TBH_RS10975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TBH_RS10980	COG0643	Histidine kinase
TBH_RS10980	COG2198	Histidine kinase
TBH_RS10985	COG0835	chemotaxis
TBH_RS10990	COG0840	transmembrane signaling receptor activity
TBH_RS10990	COG0840	transmembrane signaling receptor activity
TBH_RS11000	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
TBH_RS11005	COG2201	protein-glutamate methylesterase activity
TBH_RS11020	COG0077	Prephenate dehydratase
TBH_RS11020	COG1605	Chorismate mutase
TBH_RS11025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TBH_RS11030	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
TBH_RS11040	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TBH_RS11045	COG0402	S-adenosylhomocysteine deaminase activity
TBH_RS11050	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TBH_RS11060	COG1028	Short-chain dehydrogenase reductase Sdr
TBH_RS11075	COG0617	tRNA 3'-terminal CCA addition
TBH_RS11090	COG2010	Cytochrome c
TBH_RS11110	COG0714	Associated with various cellular activities
TBH_RS11135	COG1643	Atp-dependent helicase
TBH_RS11140	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
TBH_RS11160	COG3547	Transposase (IS116 IS110 IS902 family)
TBH_RS11190	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TBH_RS11195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TBH_RS11245	COG0446	pyridine nucleotide-disulphide oxidoreductase
TBH_RS11250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TBH_RS11280	COG3436	PFAM IS66 Orf2 family protein
TBH_RS11285	COG4372	Transposase
TBH_RS11310	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
TBH_RS11325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TBH_RS11330	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
TBH_RS11330	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TBH_RS11345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TBH_RS11360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TBH_RS11370	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
TBH_RS11395	COG2814	Major facilitator Superfamily
TBH_RS11415	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TBH_RS11420	COG1538	Outer membrane efflux protein
TBH_RS11430	COG1132	(ABC) transporter
TBH_RS11440	COG4566	intracellular signal transduction
TBH_RS11445	COG4191	Histidine kinase
TBH_RS11460	COG0513	Belongs to the DEAD box helicase family
TBH_RS11465	COG1671	Belongs to the UPF0178 family
TBH_RS11500	COG1592	Rubrerythrin
TBH_RS11505	COG0583	DNA-binding transcription factor activity
TBH_RS11510	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TBH_RS11515	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
TBH_RS11550	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
TBH_RS11565	COG2885	chlorophyll binding
TBH_RS11570	COG0823	Involved in the tonB-independent uptake of proteins
TBH_RS11590	COG0824	Thioesterase
TBH_RS11595	COG2255	four-way junction helicase activity
TBH_RS11600	COG0632	four-way junction helicase activity
TBH_RS11605	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TBH_RS11610	COG0217	transcriptional regulatory protein
TBH_RS11615	COG2095	MarC family integral membrane protein
TBH_RS11635	COG0429	hydrolase of the alpha beta-hydrolase fold
TBH_RS11640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TBH_RS11655	COG0300	oxidoreductase activity
TBH_RS11660	COG2918	glutathione biosynthetic process
TBH_RS11665	COG0793	Belongs to the peptidase S41A family
TBH_RS11675	COG3956	TIGRFAM MazG family protein
TBH_RS11720	COG0488	(ABC) transporter
TBH_RS11730	COG0166	Belongs to the GPI family
TBH_RS11735	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TBH_RS11750	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
TBH_RS11755	COG0297	glycogen (starch) synthase activity
TBH_RS11765	COG1595	DNA-templated transcription, initiation
TBH_RS11780	COG0058	SHG alpha-glucan phosphorylase activity
TBH_RS11790	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TBH_RS11800	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TBH_RS11805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TBH_RS11830	COG0300	oxidoreductase activity
TBH_RS11845	COG1022	Amp-dependent synthetase and ligase
TBH_RS11855	COG0717	Belongs to the dCTP deaminase family
TBH_RS11885	COG0288	reversible hydration of carbon dioxide
TBH_RS11935	COG1131	(ABC) transporter
TBH_RS11955	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TBH_RS11965	COG0194	GDP metabolic process
TBH_RS11970	COG1561	YicC-like family, N-terminal region
TBH_RS11975	COG2815	serine threonine protein kinase
TBH_RS11975	COG0515	serine threonine protein kinase
TBH_RS11985	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TBH_RS12005	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
TBH_RS12005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
TBH_RS12025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TBH_RS12040	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TBH_RS12050	COG4969	Belongs to the N-Me-Phe pilin family
TBH_RS12090	COG4191	Histidine kinase
TBH_RS12095	COG4566	intracellular signal transduction
TBH_RS12105	COG3258	Cytochrome c
TBH_RS12135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TBH_RS12140	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TBH_RS12175	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TBH_RS12235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TBH_RS12245	COG0137	argininosuccinate synthase activity
TBH_RS12255	COG0442	prolyl-tRNA aminoacylation
TBH_RS12260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TBH_RS12270	COG1489	DNA binding
TBH_RS12285	COG1254	Belongs to the acylphosphatase family
TBH_RS12290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TBH_RS12305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TBH_RS12310	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TBH_RS12325	COG1295	ribonuclease BN
TBH_RS12325	COG1959	2 iron, 2 sulfur cluster binding
TBH_RS12330	COG1393	Belongs to the ArsC family
TBH_RS12345	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
TBH_RS12350	COG1238	metal cluster binding
TBH_RS12380	COG2974	May be involved in recombination
TBH_RS12410	COG0277	FAD linked oxidase domain protein
TBH_RS12415	COG0300	oxidoreductase activity
TBH_RS12440	COG1511	domain protein
TBH_RS12440	COG3264	Mechanosensitive ion channel
TBH_RS12445	COG0205	6-phosphofructokinase activity
TBH_RS12480	COG2890	protein-(glutamine-N5) methyltransferase activity
TBH_RS12500	COG0583	DNA-binding transcription factor activity
TBH_RS12510	COG2067	long-chain fatty acid transport protein
TBH_RS12515	COG1902	pentaerythritol trinitrate reductase activity
TBH_RS12520	COG2210	Belongs to the sulfur carrier protein TusA family
TBH_RS12525	COG0425	Belongs to the sulfur carrier protein TusA family
TBH_RS12530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TBH_RS12535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TBH_RS12535	COG1648	precorrin-2 dehydrogenase activity
TBH_RS12545	COG2197	response regulator
TBH_RS12550	COG3850	Histidine kinase
TBH_RS12555	COG0617	tRNA 3'-terminal CCA addition
TBH_RS12560	COG5265	(ABC) transporter
TBH_RS12595	COG0308	aminopeptidase N
TBH_RS12600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
TBH_RS12605	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
TBH_RS12625	COG1797	cobyrinic acid a,c-diamide synthase activity
TBH_RS12660	COG2920	part of a sulfur-relay system
TBH_RS12670	COG2923	Belongs to the DsrF TusC family
TBH_RS12675	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
TBH_RS12680	COG2221	Nitrite and sulphite reductase 4Fe-4S
TBH_RS12685	COG2221	Nitrite and sulphite reductase 4Fe-4S
TBH_RS12765	COG4783	chaperone-mediated protein folding
TBH_RS12795	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TBH_RS12830	COG2205	protein histidine kinase activity
TBH_RS12830	COG5002	protein histidine kinase activity
TBH_RS12830	COG0784	Response regulator, receiver
TBH_RS12880	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TBH_RS12885	COG3318	Belongs to the UPF0149 family
TBH_RS12885	COG3012	SEC-C Motif Domain Protein
TBH_RS12890	COG0339	signal peptide processing
TBH_RS12900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TBH_RS12905	COG0306	phosphate transporter
TBH_RS12910	COG1368	sulfuric ester hydrolase activity
TBH_RS12915	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TBH_RS12945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TBH_RS12950	COG0581	inorganic phosphate transmembrane transporter activity
TBH_RS12955	COG0573	inorganic phosphate transmembrane transporter activity
TBH_RS12970	COG2890	protein-(glutamine-N5) methyltransferase activity
TBH_RS12985	COG0367	asparagine synthase
TBH_RS12990	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TBH_RS12995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TBH_RS13030	COG0438	transferase activity, transferring glycosyl groups
TBH_RS13045	COG0517	IMP dehydrogenase activity
TBH_RS13080	COG1216	Glycosyl transferase, family 2
TBH_RS13085	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TBH_RS13090	COG0438	transferase activity, transferring glycosyl groups
TBH_RS13105	COG1216	Glycosyl transferase, family 2
TBH_RS13105	COG0463	Glycosyl transferase, family 2
TBH_RS13110	COG0438	transferase activity, transferring glycosyl groups
TBH_RS13125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TBH_RS13135	COG0583	DNA-binding transcription factor activity
TBH_RS13140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TBH_RS13150	COG2972	Histidine kinase
TBH_RS13150	COG0745	RESPONSE REGULATOR receiver
TBH_RS13155	COG0165	Argininosuccinate lyase
TBH_RS13165	COG0004	ammonium transporteR
TBH_RS13170	COG0347	Belongs to the P(II) protein family
TBH_RS13190	COG0606	chelatase, subunit chli
TBH_RS13200	COG0156	8-amino-7-oxononanoate synthase activity
TBH_RS13220	COG0488	(ABC) transporter
TBH_RS13235	COG3065	identical protein binding
TBH_RS13245	COG3100	YcgL domain-containing protein
TBH_RS13265	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TBH_RS13275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
TBH_RS13285	COG0469	pyruvate kinase activity
TBH_RS13290	COG0126	phosphoglycerate kinase activity
TBH_RS13295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TBH_RS13300	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
TBH_RS13310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TBH_RS13315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TBH_RS13320	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TBH_RS13325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TBH_RS13335	COG0643	Histidine kinase
TBH_RS13335	COG0784	Response regulator, receiver
TBH_RS13335	COG2198	Histidine kinase
TBH_RS13335	COG0643	Histidine kinase
TBH_RS13335	COG0784	Response regulator, receiver
TBH_RS13335	COG2198	Histidine kinase
TBH_RS13340	COG0840	transmembrane signaling receptor activity
TBH_RS13370	COG0189	ligase activity
TBH_RS13380	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
TBH_RS13385	COG1678	Uncharacterized ACR, COG1678
TBH_RS13390	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
TBH_RS13395	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
TBH_RS13400	COG0540	Belongs to the ATCase OTCase family
TBH_RS13410	COG0543	2 iron, 2 sulfur cluster binding
TBH_RS13440	COG1872	DUF167
TBH_RS13460	COG2807	transmembrane transport
TBH_RS13465	COG0708	Exodeoxyribonuclease III
TBH_RS13490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TBH_RS13505	COG0501	Belongs to the peptidase M48B family
TBH_RS13520	COG0543	2 iron, 2 sulfur cluster binding
TBH_RS13520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TBH_RS13525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TBH_RS13595	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TBH_RS13600	COG2204	response regulator
TBH_RS13610	COG5002	protein histidine kinase activity
TBH_RS13625	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
TBH_RS13630	COG1194	a g-specific adenine glycosylase
TBH_RS13640	COG1999	signal sequence binding
TBH_RS13655	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
TBH_RS13660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TBH_RS13665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
TBH_RS13685	COG0012	GTP binding
TBH_RS13745	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TBH_RS13750	COG1196	nuclear chromosome segregation
TBH_RS13750	COG0739	heme binding
TBH_RS13750	COG0741	lytic transglycosylase activity
TBH_RS13755	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
TBH_RS13765	COG0316	Belongs to the HesB IscA family
TBH_RS13770	COG3266	domain, Protein
TBH_RS13770	COG4932	domain protein
TBH_RS13770	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
TBH_RS13785	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TBH_RS13795	COG1981	membrane
TBH_RS13800	COG0786	glutamate:sodium symporter activity
TBH_RS13855	COG0535	radical SAM domain protein
TBH_RS13875	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TBH_RS13910	COG0210	DNA helicase
TBH_RS13945	COG3022	response to hydroperoxide
TBH_RS13950	COG0659	secondary active sulfate transmembrane transporter activity
TBH_RS13955	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
TBH_RS13995	COG2801	Transposase and inactivated derivatives
TBH_RS14095	COG2920	part of a sulfur-relay system
TBH_RS14100	COG1136	(ABC) transporter
TBH_RS14100	COG0577	efflux transmembrane transporter activity
TBH_RS14105	COG1136	(ABC) transporter
TBH_RS14105	COG0577	efflux transmembrane transporter activity
TBH_RS14125	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TBH_RS14130	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TBH_RS14135	COG1466	dna polymerase III delta subunit
TBH_RS14145	COG0495	leucyl-tRNA aminoacylation
TBH_RS14170	COG0535	radical SAM domain protein
TBH_RS14180	COG3706	GGDEF domain
TBH_RS14195	COG1410	methionine synthase
TBH_RS14195	COG0646	methionine synthase
TBH_RS14215	COG1444	tRNA N-acetyltransferase activity
TBH_RS14235	COG2353	YceI-like domain
TBH_RS14240	COG3038	cytochrome b561
TBH_RS14260	COG0741	lytic transglycosylase activity
TBH_RS14260	COG1196	nuclear chromosome segregation
TBH_RS14260	COG0739	heme binding
TBH_RS14275	COG0667	Aldo Keto reductase
TBH_RS14285	COG0482	sulfurtransferase activity
TBH_RS14290	COG0425	Belongs to the sulfur carrier protein TusA family
TBH_RS14295	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TBH_RS14300	COG0174	glutamine synthetase
TBH_RS14335	COG0314	molybdopterin synthase activity
TBH_RS14340	COG0714	Associated with various cellular activities
TBH_RS14345	COG1233	COG1233 Phytoene dehydrogenase and related
TBH_RS14360	COG2048	Heterodisulfide reductase, subunit B
TBH_RS14425	COG2205	protein histidine kinase activity
TBH_RS14430	COG0745	RESPONSE REGULATOR receiver
TBH_RS14440	COG0842	Transport permease protein
TBH_RS14445	COG0842	Transport permease protein
TBH_RS14450	COG1131	(ABC) transporter
TBH_RS14485	COG0438	transferase activity, transferring glycosyl groups
TBH_RS14490	COG0859	PFAM glycosyl transferase family 9
TBH_RS14495	COG0529	Catalyzes the synthesis of activated sulfate
TBH_RS14515	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
TBH_RS14530	COG0784	Response regulator, receiver
TBH_RS14530	COG2205	protein histidine kinase activity
TBH_RS14570	COG0840	transmembrane signaling receptor activity
TBH_RS14635	COG4555	ABC transporter
TBH_RS14640	COG1668	transmembrane transport
TBH_RS14645	COG1278	Cold shock
TBH_RS14650	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TBH_RS14655	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
TBH_RS14700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TBH_RS14720	COG1702	phosphate starvation-inducible protein PhoH
TBH_RS14725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TBH_RS14730	COG4535	Mg2 and Co2 transporter CorC
TBH_RS14740	COG0815	Transfers the fatty acyl group on membrane lipoproteins
TBH_RS14755	COG0432	Pfam Uncharacterised protein family UPF0047
TBH_RS14765	COG0445	tRNA wobble uridine modification
TBH_RS14770	COG0714	Associated with various cellular activities
TBH_RS14790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TBH_RS14795	COG0706	membrane insertase activity
TBH_RS14800	COG0594	ribonuclease P activity
TBH_RS14925	COG0751	glycine-tRNA ligase activity
TBH_RS14930	COG0751	glycine-tRNA ligase activity
TBH_RS15000	COG2197	response regulator
TBH_RS15025	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TBH_RS15050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TBH_RS15065	COG2226	methyltransferase
TBH_RS15085	COG1169	isochorismate synthase
TBH_RS15095	COG0484	heat shock protein binding
TBH_RS15100	COG1215	transferase activity, transferring glycosyl groups
TBH_RS15120	COG1404	Belongs to the peptidase S8 family
TBH_RS15155	COG3706	GGDEF domain
TBH_RS15190	COG0589	response to stress
TBH_RS15250	COG2199	diguanylate cyclase activity
TBH_RS15250	COG2203	Gaf domain
TBH_RS15320	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TBH_RS15355	COG0515	serine threonine protein kinase
TBH_RS15355	COG2815	serine threonine protein kinase
TBH_RS15375	COG4124	Belongs to the glycosyl hydrolase 26 family
TBH_RS15375	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
TBH_RS15395	COG4191	Histidine kinase
TBH_RS15400	COG2770	Histidine kinase
TBH_RS15400	COG3437	response regulator, receiver
TBH_RS15415	COG0784	Response regulator, receiver
TBH_RS15415	COG2198	Histidine kinase
TBH_RS15415	COG5002	protein histidine kinase activity
TBH_RS15425	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
TBH_RS15445	COG1999	signal sequence binding