locus-tag	class	description
HRR27_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HRR27_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HRR27_RS00015	ENOG41076HS	cation diffusion facilitator family transporter
HRR27_RS00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HRR27_RS00030	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRR27_RS00085	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HRR27_RS00095	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HRR27_RS00105	ENOG4105EMN	RNA polymerase sigma factor
HRR27_RS00150	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HRR27_RS00155	ENOG4105J0Q	Transcriptional regulator
HRR27_RS00160	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HRR27_RS00165	ENOG410903C	(LipO)protein
HRR27_RS00170	ENOG4105C5Q	Transcriptional regulator
HRR27_RS00175	ENOG4107Y03	Nitroreductase
HRR27_RS00185	ENOG4105C7K	acetolactate synthase
HRR27_RS00195	ENOG4105CRE	cytochrome C
HRR27_RS00200	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
HRR27_RS00205	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HRR27_RS00215	ENOG4105C2M	dna polymerase I
HRR27_RS00220	ENOG4105CUV	Homoserine Kinase
HRR27_RS00225	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HRR27_RS00240	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HRR27_RS00245	ENOG4108IJ6	ABC transporter
HRR27_RS00250	ENOG4107QKW	extracellular solute-binding protein family 1
HRR27_RS00255	ENOG4107RCV	ABC transporter, permease
HRR27_RS00260	ENOG4105VEJ	Heat shock protein
HRR27_RS00265	ENOG4105KJM	monovalent cation h antiporter subunit g
HRR27_RS00270	ENOG4105W4C	monovalent cation H antiporter subunit F
HRR27_RS00280	ENOG4107R4Z	monovalent cation h antiporter subunit d
HRR27_RS00285	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HRR27_RS00290	ENOG4105D65	subunit l
HRR27_RS00295	ENOG4105BZU	Histidine kinase
HRR27_RS00300	ENOG4105BZU	Histidine kinase
HRR27_RS00355	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HRR27_RS00380	ENOG4105DGW	oligopeptidase A
HRR27_RS00385	ENOG4107G9V	glycosyl transferase, family 39
HRR27_RS00405	ENOG4105BZU	Histidine kinase
HRR27_RS00420	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HRR27_RS00435	ENOG4105DS1	cytochrome b561
HRR27_RS00440	ENOG4105EXG	Transcriptional regulator
HRR27_RS00450	ENOG4105CEY	Amp-dependent synthetase and ligase
HRR27_RS00455	ENOG4105CD5	CoA-binding domain protein
HRR27_RS00495	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HRR27_RS00510	ENOG4106371	Methyltransferase
HRR27_RS00520	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HRR27_RS00525	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HRR27_RS00535	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HRR27_RS00570	ENOG4105K63	Thioredoxin
HRR27_RS00600	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HRR27_RS00605	ENOG4105CH7	arginosuccinase
HRR27_RS00615	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HRR27_RS00640	ENOG4105HDD	phospholipase
HRR27_RS00650	ENOG4105CGK	Exodeoxyribonuclease III
HRR27_RS00660	ENOG4105CIY	formyltetrahydrofolate deformylase
HRR27_RS00670	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HRR27_RS00675	ENOG4105E0X	reductase
HRR27_RS00680	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HRR27_RS00690	ENOG4105DWF	phosphomethylpyrimidine kinase
HRR27_RS00700	ENOG4105CBX	hi0933 family
HRR27_RS00725	ENOG4108Z0R	Transferase
HRR27_RS00740	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HRR27_RS00745	ENOG4105E2X	shikimate dehydrogenase
HRR27_RS00755	ENOG4105D52	delta-aminolevulinic acid dehydratase
HRR27_RS00775	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HRR27_RS00780	ENOG4105M00	molybdopterin converting factor, subunit 1
HRR27_RS00785	ENOG4108ZAF	Molybdopterin
HRR27_RS00790	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HRR27_RS00800	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HRR27_RS00805	ENOG41082IR	Excinuclease ABC C subunit domain protein
HRR27_RS00810	ENOG4105BZU	Histidine kinase
HRR27_RS00825	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HRR27_RS00845	ENOG4105C25	Primosomal protein n'
HRR27_RS00850	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HRR27_RS00855	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HRR27_RS00865	ENOG4105BZG	amino acid carrier protein
HRR27_RS00890	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HRR27_RS00895	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HRR27_RS00900	ENOG4105MJ2	Competence protein
HRR27_RS00905	ENOG4105PGM	cation diffusion facilitator family transporter
HRR27_RS00915	ENOG4105C7Z	Conserved Protein
HRR27_RS00925	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HRR27_RS00930	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HRR27_RS00940	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HRR27_RS00945	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HRR27_RS00950	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HRR27_RS00955	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HRR27_RS00960	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HRR27_RS00965	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HRR27_RS00980	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HRR27_RS00990	ENOG4105C58	cytochrome c oxidase accessory protein ccog
HRR27_RS01000	ENOG4105C59	p-type ATPase
HRR27_RS01025	ENOG4105BZU	Histidine kinase
HRR27_RS01030	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HRR27_RS01040	ENOG4105CI3	gtp-binding protein typa
HRR27_RS01050	ENOG4105CUC	YeeE YedE family protein
HRR27_RS01065	ENOG41083KI	ribonuclease, T2
HRR27_RS01080	ENOG4105BZU	Histidine kinase
HRR27_RS01100	ENOG4108VWS	Yaeq family
HRR27_RS01105	ENOG4105C1J	atp-dependent rna helicase
HRR27_RS01110	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HRR27_RS01115	ENOG4108MGY	Histidine kinase
HRR27_RS01120	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HRR27_RS01120	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HRR27_RS01125	ENOG4107TPY	serine threonine protein kinase
HRR27_RS01130	ENOG41060A7	DNA polymerase beta domain protein region
HRR27_RS01160	ENOG4105BZU	Histidine kinase
HRR27_RS01165	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
HRR27_RS01170	ENOG4108VCT	Sulfite exporter TauE/SafE
HRR27_RS01190	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HRR27_RS01200	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HRR27_RS01215	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HRR27_RS01220	ENOG4105C1A	potassium transporter peripheral membrane
HRR27_RS01225	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HRR27_RS01230	ENOG4105ES5	Histidine kinase
HRR27_RS01240	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HRR27_RS01245	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HRR27_RS01250	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HRR27_RS01255	ENOG4105C79	DNA protecting protein DprA
HRR27_RS01265	ENOG4105C75	arginyL-tRNA synthetase
HRR27_RS01280	ENOG4105W0Z	cytoplasmic protein
HRR27_RS01285	ENOG4105C0P	Mg chelatase subunit ChlI
HRR27_RS01300	ENOG4105WH1	Two component transcriptional regulator luxr family
HRR27_RS01315	ENOG4105CDV	Ompa motb domain protein
HRR27_RS01320	ENOG4105C0A	alcohol dehydrogenase
HRR27_RS01325	ENOG4105C4R	Atp-dependent dna helicase
HRR27_RS01330	ENOG4107Y49	methyltransferase
HRR27_RS01345	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HRR27_RS01350	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HRR27_RS01360	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
HRR27_RS01365	ENOG4105C3Q	Glycosyl transferase, family 2
HRR27_RS01375	ENOG4105BZW	Glycerate kinase
HRR27_RS01395	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HRR27_RS01400	ENOG4105VNG	YcgL domain-containing protein
HRR27_RS01410	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HRR27_RS01435	ENOG4105BZS	acriflavin resistance protein
HRR27_RS01440	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HRR27_RS01445	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HRR27_RS01450	ENOG4105BZA	Phosphoglycerate kinase
HRR27_RS01455	ENOG4105CA9	Pyruvate kinase
HRR27_RS01460	ENOG4105D2N	Aldolase
HRR27_RS01465	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
HRR27_RS01495	ENOG4105KNY	Microcompartments protein
HRR27_RS01500	ENOG4105KNY	Microcompartments protein
HRR27_RS01505	ENOG4105KNY	Microcompartments protein
HRR27_RS01565	ENOG4105C8V	SAICAR synthetase
HRR27_RS01575	ENOG4105DJV	ribulose-phosphate 3-epimerase
HRR27_RS01580	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HRR27_RS01585	ENOG4105CRQ	synthase (Component I)
HRR27_RS01590	ENOG4105DDQ	anthranilate synthase
HRR27_RS01595	ENOG4107QYG	anthranilate phosphoribosyltransferase
HRR27_RS01600	ENOG4105WD1	Membrane
HRR27_RS01605	ENOG4105EUP	HipA domain protein
HRR27_RS01630	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HRR27_RS01640	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HRR27_RS01645	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HRR27_RS01655	ENOG4108UKZ	OsmC family
HRR27_RS01665	ENOG4105C1J	atp-dependent rna helicase
HRR27_RS01670	ENOG4105EWT	decarboxylase family
HRR27_RS01675	ENOG4105IPI	Membrane
HRR27_RS01705	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
HRR27_RS01710	ENOG4105CKI	cobalamin synthesis protein
HRR27_RS01715	ENOG4107RSR	Malate quinone oxidoreductase
HRR27_RS01725	ENOG410642E	Short chain dehydrogenase
HRR27_RS01735	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HRR27_RS01740	ENOG4105DR5	peptidase
HRR27_RS01750	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HRR27_RS01755	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HRR27_RS01760	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HRR27_RS01770	ENOG4105E14	MotA TolQ exbB proton channel
HRR27_RS01790	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRR27_RS01795	ENOG4105BZU	Histidine kinase
HRR27_RS01805	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HRR27_RS01805	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HRR27_RS01820	ENOG4105CNG	UPF0061 protein
HRR27_RS01830	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRR27_RS01835	ENOG4107RD7	Flagellar Motor Protein, MotA
HRR27_RS01840	ENOG4106VK6	Flagellar motor protein
HRR27_RS01845	ENOG4105D06	uba thif-type nad fad binding protein
HRR27_RS01850	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HRR27_RS01855	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HRR27_RS01860	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HRR27_RS01880	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HRR27_RS01885	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HRR27_RS01890	ENOG4105C3G	gtp-binding protein
HRR27_RS02015	ENOG4105BZU	Histidine kinase
HRR27_RS02020	ENOG4108IY8	ABC, transporter
HRR27_RS02030	ENOG4105DG7	nitrate ABC transporter
HRR27_RS02050	ENOG4107QZF	nitrite reductase NADPH large subunit
HRR27_RS02065	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
HRR27_RS02075	ENOG4105C8Q	Methyl-accepting chemotaxis
HRR27_RS02080	ENOG4105BZU	Histidine kinase
HRR27_RS02100	ENOG4105GVR	general secretion pathway protein D
HRR27_RS02105	ENOG4107QHF	type ii secretion system protein e
HRR27_RS02110	ENOG4105D7Q	type ii secretion system
HRR27_RS02115	ENOG4108VAU	general secretion pathway protein G
HRR27_RS02120	ENOG4105VWV	general secretion pathway protein h
HRR27_RS02130	ENOG4108WWZ	General secretion pathway protein J
HRR27_RS02135	ENOG4108RTD	type II secretion system protein K
HRR27_RS02140	ENOG4108ADH	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
HRR27_RS02175	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HRR27_RS02185	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HRR27_RS02195	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HRR27_RS02200	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HRR27_RS02215	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HRR27_RS02230	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HRR27_RS02235	ENOG4105C2X	Arabinose 5-phosphate isomerase
HRR27_RS02240	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HRR27_RS02250	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
HRR27_RS02255	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HRR27_RS02260	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HRR27_RS02270	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HRR27_RS02280	ENOG41090SZ	ABC-2 type transporter
HRR27_RS02285	ENOG4105EY8	ABC transporter
HRR27_RS02305	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
HRR27_RS02310	ENOG4107TXM	Nad-dependent epimerase dehydratase
HRR27_RS02320	ENOG4105F8J	Adenylate Guanylate cyclase
HRR27_RS02330	ENOG4108W63	CRP FNR family transcriptional regulator
HRR27_RS02385	ENOG4108YGG	dna repair protein
HRR27_RS02395	ENOG4108KU3	Integrase
HRR27_RS02405	ENOG4105VUH	addiction module killer protein
HRR27_RS02475	ENOG4108KU3	Integrase
HRR27_RS02540	ENOG4105DFG	type I secretion outer membrane protein
HRR27_RS02545	ENOG4108JJ6	Type I secretion system ATPase
HRR27_RS02565	ENOG41080HT	Transcriptional regulator, arsr family
HRR27_RS02570	ENOG4105CN1	protease
HRR27_RS02575	ENOG4107S0N	DJ-1 family
HRR27_RS02585	ENOG4107S2Z	UPF0761 membrane protein
HRR27_RS02590	ENOG4105EHG	Permease protein
HRR27_RS02595	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HRR27_RS02615	ENOG4105K4U	addiction module toxin, RelE StbE family
HRR27_RS02650	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HRR27_RS02655	ENOG4105CHH	sulfate transporter
HRR27_RS02660	ENOG4105CZK	Aspartate kinase
HRR27_RS02665	ENOG4105CAH	Chromate
HRR27_RS02670	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
HRR27_RS02675	ENOG4108JPW	Aminotransferase
HRR27_RS02680	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
HRR27_RS02690	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HRR27_RS02705	ENOG4105C5H	ABC transporter
HRR27_RS02710	ENOG4105BZU	Histidine kinase
HRR27_RS02715	ENOG4105ETX	regulatoR
HRR27_RS02720	ENOG4105GR3	Histidine kinase
HRR27_RS02730	ENOG4107QX9	Thiol disulfide interChange protein
HRR27_RS02735	ENOG4105FQ6	thiopurine methyltransferase
HRR27_RS02740	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HRR27_RS02750	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HRR27_RS02760	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HRR27_RS02765	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HRR27_RS02770	ENOG4105KI2	Urea amidohydrolase subunit beta
HRR27_RS02775	ENOG4105CQM	Urea amidohydrolase subunit alpha
HRR27_RS02780	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HRR27_RS02785	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HRR27_RS02790	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HRR27_RS02805	ENOG4108IV0	ABC, transporter
HRR27_RS02810	ENOG4105C0Z	ABC transporter
HRR27_RS02820	ENOG4105C32	Amino acid ABC transporter (Permease)
HRR27_RS02830	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HRR27_RS02835	ENOG4105CKI	cobalamin synthesis protein
HRR27_RS02845	ENOG4105F4R	Transcriptional regulator mode
HRR27_RS02890	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HRR27_RS02905	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HRR27_RS02920	ENOG4105KXI	murein peptide amidase A
HRR27_RS02925	ENOG4105CZX	twitching motility protein
HRR27_RS02930	ENOG4105CZX	twitching motility protein
HRR27_RS02940	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HRR27_RS02945	ENOG4108M8S	permease YjgP YjgQ family protein
HRR27_RS02950	ENOG4108K5H	permease YjgP YjgQ family protein
HRR27_RS02955	ENOG4105D6S	protein involved in catabolism of external DNA
HRR27_RS02960	ENOG4107QKV	phosphomannomutase
HRR27_RS02965	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HRR27_RS02975	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HRR27_RS02980	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HRR27_RS02985	ENOG4105KT5	UmuD protein
HRR27_RS03030	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HRR27_RS03040	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HRR27_RS03055	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HRR27_RS03060	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HRR27_RS03065	ENOG4105VIE	preprotein translocase, subunit YajC
HRR27_RS03070	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HRR27_RS03075	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HRR27_RS03135	ENOG4108C33	Resolvase
HRR27_RS03175	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
HRR27_RS03185	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HRR27_RS03205	ENOG4105DFS	Conserved Protein
HRR27_RS03215	ENOG4105PSV	Polysaccharide Biosynthesis Protein
HRR27_RS03225	ENOG4105K64	Glycosyl transferase, family 2
HRR27_RS03235	ENOG4105CG5	Glycosyl transferase (Group 1
HRR27_RS03245	ENOG4105CPK	Glycosyl transferase (Group 1
HRR27_RS03255	ENOG4105EXC	Acyl-transferase
HRR27_RS03265	ENOG4105D3Q	Sugar transferase
HRR27_RS03270	ENOG4105CMR	udp-glucose 4-epimerase
HRR27_RS03285	ENOG4105CMR	udp-glucose 4-epimerase
HRR27_RS03305	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HRR27_RS03315	ENOG4105D3Q	Sugar transferase
HRR27_RS03345	ENOG4105CDV	Ompa motb domain protein
HRR27_RS03350	ENOG4105CJW	magnesium transporter
HRR27_RS03355	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HRR27_RS03360	ENOG4108IUZ	ABC transporter
HRR27_RS03375	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HRR27_RS03390	ENOG4105DHJ	ABC, transporter
HRR27_RS03395	ENOG4105CY3	ABC transporter, permease
HRR27_RS03400	ENOG4107PE3	Mammalian cell entry related domain protein
HRR27_RS03415	ENOG4105DA5	(ABC) transporter
HRR27_RS03420	ENOG4105E3A	(ABC) transporter
HRR27_RS03430	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HRR27_RS03435	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HRR27_RS03440	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HRR27_RS03445	ENOG4107QNR	UPF0135 protein
HRR27_RS03450	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HRR27_RS03455	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HRR27_RS03460	ENOG4105EIX	cytochrome c1
HRR27_RS03465	ENOG4105CBC	glutamate synthase
HRR27_RS03470	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HRR27_RS03475	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
HRR27_RS03485	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
HRR27_RS03490	ENOG4105ECY	inositol monophosphatase
HRR27_RS03495	ENOG4108JU6	CBS domain protein
HRR27_RS03505	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HRR27_RS03510	ENOG4105K5M	30s ribosomal protein S16
HRR27_RS03515	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HRR27_RS03520	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HRR27_RS03525	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HRR27_RS03530	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HRR27_RS03545	ENOG4105T95	Thiol disulfide interChange protein
HRR27_RS03575	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HRR27_RS03580	ENOG4105I03	Flagellin
HRR27_RS03600	ENOG4108YZA	Nitrogen regulatory protein pii
HRR27_RS03610	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HRR27_RS03615	ENOG4105C5F	glutamine synthetase
HRR27_RS03625	ENOG4105C8U	phosphate abc transporter
HRR27_RS03630	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HRR27_RS03635	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HRR27_RS03640	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HRR27_RS03645	ENOG4105BZU	Histidine kinase
HRR27_RS03650	ENOG4108UYB	regulatoR
HRR27_RS03675	ENOG4105CJ3	phosphate transporter
HRR27_RS03680	ENOG4105DJH	phosphate
HRR27_RS03700	ENOG4105M85	Bola protein
HRR27_RS03710	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HRR27_RS03715	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HRR27_RS03720	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HRR27_RS03725	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HRR27_RS03730	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HRR27_RS03735	ENOG4105EHM	Aminoglycoside phosphotransferase
HRR27_RS03740	ENOG4108S0S	Nucleotidyl transferase
HRR27_RS03745	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HRR27_RS03750	ENOG4107QMS	site-determining protein
HRR27_RS03755	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HRR27_RS03760	ENOG4105D1Q	UPF0246 protein
HRR27_RS03765	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HRR27_RS03800	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HRR27_RS03815	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HRR27_RS03820	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HRR27_RS03825	ENOG4108Z43	UPF0250 protein
HRR27_RS03830	ENOG4105DZ1	carboxypeptidase
HRR27_RS03835	ENOG4105CNI	cell division protein FtsW
HRR27_RS03840	ENOG4105CJN	penicillin-binding protein
HRR27_RS03850	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HRR27_RS03860	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HRR27_RS03865	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HRR27_RS03870	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HRR27_RS03885	ENOG4105D0M	Protease HtpX homolog
HRR27_RS03895	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HRR27_RS03905	ENOG4105M15	transport protein ExbD
HRR27_RS03910	ENOG4105M8K	biopolymer transport protein
HRR27_RS03925	ENOG4105GAV	receptor
HRR27_RS03930	ENOG4105EAC	phosphoserine phosphatase
HRR27_RS03950	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HRR27_RS03955	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HRR27_RS03960	ENOG4108Z6B	deaminase
HRR27_RS03965	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
HRR27_RS03970	ENOG4105CBS	Chea signal transduction histidine kinase
HRR27_RS03985	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HRR27_RS03990	ENOG4105BZU	Histidine kinase
HRR27_RS04000	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HRR27_RS04020	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HRR27_RS04040	ENOG4105E7D	Protein of unknown function (DUF3375)
HRR27_RS04090	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HRR27_RS04095	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HRR27_RS04105	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HRR27_RS04110	ENOG4107TH8	cina domain protein
HRR27_RS04115	ENOG4105CQZ	Histidine kinase
HRR27_RS04120	ENOG4105BZU	Histidine kinase
HRR27_RS04165	ENOG4105E5H	Transposase
HRR27_RS04215	ENOG4105BZU	Histidine kinase
HRR27_RS04230	ENOG4105F5W	AtP-binding protein
HRR27_RS04255	ENOG4105BZU	Histidine kinase
HRR27_RS04265	ENOG4105C8Q	Methyl-accepting chemotaxis
HRR27_RS04270	ENOG4105C31	Tryptophanyl-tRNA synthetase
HRR27_RS04280	ENOG4105DJ0	Poly(A) Polymerase
HRR27_RS04285	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HRR27_RS04290	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HRR27_RS04295	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HRR27_RS04300	ENOG4105E14	MotA TolQ exbB proton channel
HRR27_RS04305	ENOG4106VK6	Flagellar motor protein
HRR27_RS04310	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HRR27_RS04315	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HRR27_RS04325	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HRR27_RS04330	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HRR27_RS04335	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HRR27_RS04340	ENOG4107QN2	dihydrolipoyl dehydrogenase
HRR27_RS04345	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HRR27_RS04350	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HRR27_RS04355	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HRR27_RS04360	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HRR27_RS04365	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HRR27_RS04370	ENOG4105CD8	aminopeptidase N
HRR27_RS04430	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HRR27_RS04435	ENOG4108ZC9	flagellar basal-body rod protein flgc
HRR27_RS04440	ENOG410822I	Flagellar hook capping protein
HRR27_RS04445	ENOG4105BZE	flagellar hook protein, FlgE
HRR27_RS04450	ENOG4105CGA	flagellar basal-body rod protein FlgG
HRR27_RS04455	ENOG4105CGA	flagellar basal-body rod protein FlgG
HRR27_RS04460	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HRR27_RS04465	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HRR27_RS04470	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HRR27_RS04480	ENOG4105DTJ	flagellar hook-associated protein
HRR27_RS04485	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HRR27_RS04490	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HRR27_RS04495	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HRR27_RS04505	ENOG4105D2T	synthase
HRR27_RS04510	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
HRR27_RS04530	ENOG4105F0R	Cytidylyltransferase
HRR27_RS04540	ENOG4105I03	Flagellin
HRR27_RS04545	ENOG4105I03	Flagellin
HRR27_RS04565	ENOG4105MQ3	flagellar protein FliS
HRR27_RS04580	ENOG4105BZU	Histidine kinase
HRR27_RS04590	ENOG4105X6K	flagellar hook-basal body complex protein fliE
HRR27_RS04595	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HRR27_RS04600	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HRR27_RS04610	ENOG4108JIR	Flagellum-specific ATP synthase
HRR27_RS04625	ENOG4108NVR	Methyl-accepting chemotaxis
HRR27_RS04630	ENOG4107RD7	Flagellar Motor Protein, MotA
HRR27_RS04635	ENOG4105ER2	Ompa motb domain protein
HRR27_RS04645	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HRR27_RS04650	ENOG4105DD5	Flagellar motor switch protein
HRR27_RS04655	ENOG4105VTB	flagellar biosynthesis protein fliO
HRR27_RS04660	ENOG4105CN7	Flagellar biosynthetic protein FliP
HRR27_RS04665	ENOG4105VS8	Flagellar biosynthetic protein fliq
HRR27_RS04670	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HRR27_RS04675	ENOG4105D00	flagellar biosynthetic protein flhB
HRR27_RS04680	ENOG4105D7B	Flagellar biosynthesis protein flha
HRR27_RS04685	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HRR27_RS04695	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRR27_RS04700	ENOG4108VYJ	response regulator receiver protein
HRR27_RS04705	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HRR27_RS04715	ENOG4105YFD	chemotaxis, protein
HRR27_RS04720	ENOG4105VM1	flagellar
HRR27_RS04730	ENOG4108VYJ	response regulator receiver protein
HRR27_RS04735	ENOG4108V3W	Chemotaxis protein, CheW
HRR27_RS04745	ENOG4105BZU	Histidine kinase
HRR27_RS04750	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HRR27_RS04755	ENOG4105C8Q	Methyl-accepting chemotaxis
HRR27_RS04765	ENOG4105EGD	dinuclear metal center protein, YbgI family
HRR27_RS04770	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HRR27_RS04775	ENOG4105C3M	thioredoxin reductase
HRR27_RS04780	ENOG4105CNU	cell division protein FtsK
HRR27_RS04790	ENOG4105D1H	recombination factor protein RarA
HRR27_RS04795	ENOG4105WMR	Protein CrcB homolog
HRR27_RS04800	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HRR27_RS04815	ENOG4105DFP	Integrase
HRR27_RS04830	ENOG4105EB3	Histidine kinase
HRR27_RS04835	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HRR27_RS04870	ENOG4107SDU	Methyl-accepting chemotaxis
HRR27_RS04875	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HRR27_RS04885	ENOG4105BZU	Histidine kinase
HRR27_RS04895	ENOG4105CM6	amino acid regulated cytosolic protein
HRR27_RS04905	ENOG4105D05	Receptor
HRR27_RS04925	ENOG4105EHG	Permease protein
HRR27_RS04930	ENOG4105E0A	ABC, transporter
HRR27_RS04935	ENOG4107USA	Thioredoxin
HRR27_RS04960	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HRR27_RS04970	ENOG4105BZU	Histidine kinase
HRR27_RS04975	ENOG4105WH1	Two component transcriptional regulator luxr family
HRR27_RS04985	ENOG4108JJA	ABC, transporter
HRR27_RS04990	ENOG4105CDV	Ompa motb domain protein
HRR27_RS05070	ENOG4105E5H	Transposase
HRR27_RS05130	ENOG4105E5H	Transposase
HRR27_RS05170	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
HRR27_RS05175	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HRR27_RS05180	ENOG4105DFU	Cell wall formation (By similarity)
HRR27_RS05210	ENOG4108BPE	-transporting atpase
HRR27_RS05220	ENOG4105CQ7	ATP-dependent helicase
HRR27_RS05230	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HRR27_RS05235	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HRR27_RS05240	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRR27_RS05245	ENOG4105E66	phosphoriboisomerase A
HRR27_RS05265	ENOG4105C7B	Threonine dehydratase
HRR27_RS05275	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HRR27_RS05280	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HRR27_RS05285	ENOG4105K8N	protein family UPF0079, ATPase
HRR27_RS05290	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HRR27_RS05295	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HRR27_RS05310	ENOG4107RAQ	aminopeptidase
HRR27_RS05320	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HRR27_RS05335	ENOG4108IAB	Phoh family
HRR27_RS05340	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRR27_RS05345	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HRR27_RS05355	ENOG4108ETH	Formylglycinamide ribotide synthetase
HRR27_RS05370	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HRR27_RS05380	ENOG4105D38	putrescine abc transporter
HRR27_RS05385	ENOG4105F38	ABC transporter, permease
HRR27_RS05390	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HRR27_RS05395	ENOG4107RUE	extracellular solute-binding protein family 1
HRR27_RS05400	ENOG4105BZ8	glutamate synthase
HRR27_RS05415	ENOG4105C5H	ABC transporter
HRR27_RS05420	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HRR27_RS05425	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HRR27_RS05430	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HRR27_RS05445	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HRR27_RS05450	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HRR27_RS05455	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HRR27_RS05460	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HRR27_RS05475	ENOG4107XVI	synthase
HRR27_RS05480	ENOG4105CTB	Polyprenyl synthetase
HRR27_RS05495	ENOG4105C9M	aspartyl-trna synthetase
HRR27_RS05500	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HRR27_RS05505	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HRR27_RS05510	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HRR27_RS05515	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HRR27_RS05520	ENOG4105E02	MotA TolQ exbB proton channel
HRR27_RS05525	ENOG4105M8F	Biopolymer transport protein exbD tolR
HRR27_RS05535	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HRR27_RS05540	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HRR27_RS05550	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HRR27_RS05575	ENOG4105CUX	Signal transduction histidine kinase
HRR27_RS05580	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HRR27_RS05590	ENOG4105W39	Membrane
HRR27_RS05595	ENOG4108YZA	Nitrogen regulatory protein pii
HRR27_RS05600	ENOG4105DJ4	phosphatidylserine decarboxylase
HRR27_RS05605	ENOG4105CDH	Citrulline--aspartate ligase
HRR27_RS05610	ENOG4105VEQ	Cold shock protein
HRR27_RS05620	ENOG4108ZAI	phosphatidylglycerophosphatase a
HRR27_RS05630	ENOG4105CK2	sodium dicarboxylate symporter
HRR27_RS05635	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HRR27_RS05650	ENOG4105C8N	cysteinyl-tRNA synthetase
HRR27_RS05655	ENOG4107SC1	transglycosylase
HRR27_RS05660	ENOG4105E9H	Lytic Murein transglycosylase
HRR27_RS05665	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HRR27_RS05670	ENOG4105D1A	Methyltransferase
HRR27_RS05675	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HRR27_RS05680	ENOG4107RZZ	dna polymerase iii epsilon subunit
HRR27_RS05685	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HRR27_RS05695	ENOG4105CQ7	ATP-dependent helicase
HRR27_RS05700	ENOG4105Z6S	cytochrome C, class I
HRR27_RS05730	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HRR27_RS05735	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HRR27_RS05740	ENOG4105C4K	Nad synthetase
HRR27_RS05750	ENOG4105C34	Pseudouridine synthase
HRR27_RS05755	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HRR27_RS05765	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HRR27_RS05775	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HRR27_RS05785	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HRR27_RS05790	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HRR27_RS05795	ENOG4107QSN	dihydrolipoamide acetyltransferase
HRR27_RS05800	ENOG4107QN2	dihydrolipoyl dehydrogenase
HRR27_RS05820	ENOG4105VRT	cytoplasmic protein
HRR27_RS05825	ENOG4105DCF	alanine dehydrogenase
HRR27_RS05845	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HRR27_RS05850	ENOG4105D58	Diguanylate phosphodiesterase
HRR27_RS05860	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
HRR27_RS05870	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HRR27_RS05875	ENOG4105C1J	atp-dependent rna helicase
HRR27_RS05885	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HRR27_RS05895	ENOG4105C1J	atp-dependent rna helicase
HRR27_RS05900	ENOG4105C5H	ABC transporter
HRR27_RS05905	ENOG4108UPT	UPF0178 protein
HRR27_RS05910	ENOG4108RCM	Nitroreductase
HRR27_RS05920	ENOG4107QJE	Chromosome Partitioning Protein
HRR27_RS05935	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HRR27_RS05940	ENOG4105BZU	Histidine kinase
HRR27_RS05970	ENOG4108W1A	pseudouridine synthase
HRR27_RS05975	ENOG4108ZZ3	UPF0260 protein
HRR27_RS05985	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HRR27_RS05990	ENOG4108YXA	Membrane
HRR27_RS06020	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HRR27_RS06040	ENOG4105CFP	Peptidase U32
HRR27_RS06045	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HRR27_RS06070	ENOG4105C8Q	Methyl-accepting chemotaxis
HRR27_RS06080	ENOG4105C6T	cysteine synthase
HRR27_RS06095	ENOG4105DEF	Extracellular solute-binding protein, family 5
HRR27_RS06105	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRR27_RS06110	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HRR27_RS06120	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HRR27_RS06125	ENOG4105D64	Mechanosensitive ion channel
HRR27_RS06130	ENOG4105VV6	START domain-containing protein
HRR27_RS06135	ENOG4107R0I	Cell wall formation (By similarity)
HRR27_RS06140	ENOG4105C8J	)-transporter
HRR27_RS06160	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HRR27_RS06175	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HRR27_RS06185	ENOG4105BZU	Histidine kinase
HRR27_RS06200	ENOG4108JA2	transcriptioN-repair coupling factor
HRR27_RS06210	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
HRR27_RS06220	ENOG4105EN6	Membrane
HRR27_RS06230	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HRR27_RS06235	ENOG4105C5H	ABC transporter
HRR27_RS06245	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HRR27_RS06365	ENOG4107SDU	Methyl-accepting chemotaxis
HRR27_RS06375	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HRR27_RS06380	ENOG4105KUZ	arsenate reductase
HRR27_RS06385	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
HRR27_RS06395	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HRR27_RS06400	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HRR27_RS06405	ENOG4105CE9	30S ribosomal protein S2
HRR27_RS06410	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HRR27_RS06415	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HRR27_RS06420	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HRR27_RS06425	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HRR27_RS06430	ENOG4105KNE	Phosphatidate cytidylyltransferase
HRR27_RS06435	ENOG4105DZP	Membrane-associated zinc metalloprotease
HRR27_RS06440	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HRR27_RS06450	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRR27_RS06455	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HRR27_RS06460	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRR27_RS06465	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRR27_RS06470	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HRR27_RS06475	ENOG4107R88	Chemotaxis protein (CheV)
HRR27_RS06495	ENOG4105YK5	50S ribosomal protein L36
HRR27_RS06500	ENOG4105DVT	helicase
HRR27_RS06505	ENOG41072GX	Peptidase M22 Glycoprotease
HRR27_RS06525	ENOG4105DDY	UPF0142 protein ycaO
HRR27_RS06535	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HRR27_RS06540	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HRR27_RS06545	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HRR27_RS06550	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HRR27_RS06555	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HRR27_RS06560	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HRR27_RS06570	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HRR27_RS06575	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HRR27_RS06580	ENOG4108UM1	dedA family
HRR27_RS06585	ENOG4108K5P	(LipO)protein
HRR27_RS06595	ENOG4105CHM	Aminotransferase
HRR27_RS06600	ENOG4105D6E	homoserine dehydrogenase
HRR27_RS06610	ENOG4107QID	Threonine synthase
HRR27_RS06640	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HRR27_RS06645	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
HRR27_RS06655	ENOG4107S5T	Carbohydrate kinase
HRR27_RS06665	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HRR27_RS06670	ENOG4105N42	UPF0307 protein
HRR27_RS06685	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HRR27_RS06690	ENOG4105K9H	YciI-like protein
HRR27_RS06695	ENOG4107835	probably involved in intracellular septation (By similarity)
HRR27_RS06700	ENOG4105DB7	PHP domain protein
HRR27_RS06705	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HRR27_RS06710	ENOG4108Z4T	Peptidase M50
HRR27_RS06715	ENOG4105FE9	pseudouridine synthase
HRR27_RS06720	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRR27_RS06750	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HRR27_RS06755	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HRR27_RS06760	ENOG4105BZU	Histidine kinase
HRR27_RS06770	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HRR27_RS06805	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HRR27_RS06850	ENOG4105K5B	UPF0225 protein
HRR27_RS06855	ENOG4107QI1	Mate efflux family protein
HRR27_RS06865	ENOG41087AY	ADP-Ribose pyrophosphatase
HRR27_RS06870	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HRR27_RS06875	ENOG4105CDU	Replicative dna helicase
HRR27_RS06880	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HRR27_RS06890	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HRR27_RS06895	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HRR27_RS06900	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HRR27_RS06910	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HRR27_RS06915	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HRR27_RS06920	ENOG4105CAT	Cytidine monophosphate kinase
HRR27_RS06925	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HRR27_RS06930	ENOG4105EVN	Prephenate dehydrogenase
HRR27_RS06935	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HRR27_RS06945	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HRR27_RS06950	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HRR27_RS06955	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HRR27_RS06960	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HRR27_RS06965	ENOG4105CHR	reductase
HRR27_RS06970	ENOG4108JQ6	ABC transporter
HRR27_RS06980	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HRR27_RS06985	ENOG4105DEF	Extracellular solute-binding protein, family 5
HRR27_RS06990	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HRR27_RS07030	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HRR27_RS07035	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HRR27_RS07040	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HRR27_RS07045	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HRR27_RS07070	ENOG4107QIJ	Aconitate hydratase 2
HRR27_RS07080	ENOG4107QTF	adenylosuccinate lyase
HRR27_RS07090	ENOG4105CJ1	ABC, transporter
HRR27_RS07095	ENOG4107QWP	ABC-2 type transporter
HRR27_RS07100	ENOG4105EZE	Cupin 4 family protein
HRR27_RS07105	ENOG4105K63	Thioredoxin
HRR27_RS07115	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HRR27_RS07120	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HRR27_RS07130	ENOG41088CC	tellurite resistance protein tehB
HRR27_RS07135	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HRR27_RS07140	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HRR27_RS07145	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HRR27_RS07150	ENOG4105CHV	Transcription elongation factor NusA
HRR27_RS07155	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HRR27_RS07160	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HRR27_RS07180	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HRR27_RS07185	ENOG4105C0B	DNA polymerase III (alpha subunit)
HRR27_RS07190	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HRR27_RS07195	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HRR27_RS07205	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HRR27_RS07210	ENOG4105E33	succinate dehydrogenase
HRR27_RS07220	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HRR27_RS07230	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRR27_RS07235	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HRR27_RS07245	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HRR27_RS07250	ENOG4105CDY	transcriptional regulatory protein
HRR27_RS07270	ENOG4108R99	pseudouridine synthase
HRR27_RS07275	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HRR27_RS07280	ENOG41075W9	High frequency lysogenization protein HflD homolog
HRR27_RS07290	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HRR27_RS07300	ENOG4108VYJ	response regulator receiver protein
HRR27_RS07320	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HRR27_RS07325	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HRR27_RS07335	ENOG4105EPW	hflc protein
HRR27_RS07340	ENOG4107QJR	hflk protein
HRR27_RS07345	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HRR27_RS07350	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HRR27_RS07355	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HRR27_RS07365	ENOG4105D1F	ATP-binding protein
HRR27_RS07370	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HRR27_RS07375	ENOG4105DGN	Electron transport complex
HRR27_RS07380	ENOG4108R3D	Electron transport complex
HRR27_RS07400	ENOG4105DZB	Electron transport complex
HRR27_RS07410	ENOG4105CSM	endonuclease III
HRR27_RS07435	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRR27_RS07445	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HRR27_RS07455	ENOG4105CX6	glutaminyL-tRNA synthetase
HRR27_RS07465	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HRR27_RS07470	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HRR27_RS07485	ENOG4105EVH	UPF0753 protein
HRR27_RS07495	ENOG4105EGS	Mechanosensitive ion channel
HRR27_RS07500	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HRR27_RS07505	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HRR27_RS07510	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HRR27_RS07515	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HRR27_RS07520	ENOG4105VCH	membrane
HRR27_RS07530	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HRR27_RS07535	ENOG4105W49	UPF0434 protein
HRR27_RS07540	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HRR27_RS07545	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HRR27_RS07555	ENOG4105DAN	ATP-dependent protease
HRR27_RS07585	ENOG4108YZT	Adenosylcobinamide kinase
HRR27_RS07600	ENOG4108RRZ	Transcription elongation factor GreB
HRR27_RS07610	ENOG4105C09	Bile acid
HRR27_RS07615	ENOG4105BZU	Histidine kinase
HRR27_RS07625	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HRR27_RS07630	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HRR27_RS07640	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HRR27_RS07645	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HRR27_RS07650	ENOG4105C3F	Signal peptidase i
HRR27_RS07655	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HRR27_RS07660	ENOG4105C0H	protease
HRR27_RS07670	ENOG4108IYU	L-aspartate oxidase
HRR27_RS07675	ENOG4108V3W	Chemotaxis protein, CheW
HRR27_RS07680	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HRR27_RS07755	ENOG4105E5H	Transposase
HRR27_RS07800	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HRR27_RS07815	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HRR27_RS07820	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HRR27_RS07855	ENOG4105ECX	polysaccharide export
HRR27_RS07865	ENOG41090SZ	ABC-2 type transporter
HRR27_RS07870	ENOG4107V1M	polysaccharide export protein
HRR27_RS07880	ENOG41084CK	capsule polysaccharide
HRR27_RS07895	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HRR27_RS07905	ENOG4105CRK	lysyL-tRNA synthetase
HRR27_RS07920	ENOG4105WH1	Two component transcriptional regulator luxr family
HRR27_RS07930	ENOG41080RH	Thioredoxin
HRR27_RS07935	ENOG4105E1F	short-chain dehydrogenase reductase
HRR27_RS07940	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HRR27_RS07945	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HRR27_RS07950	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HRR27_RS07955	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HRR27_RS07965	ENOG4105WZK	nitrite reductase NADPH small subunit
HRR27_RS07975	ENOG4107RNU	major facilitator superfamily MFS_1
HRR27_RS07990	ENOG4108WQI	RNA Polymerase
HRR27_RS08000	ENOG4105FE9	pseudouridine synthase
HRR27_RS08010	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HRR27_RS08020	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HRR27_RS08030	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HRR27_RS08045	ENOG4105E8R	UPF0173 metal-dependent hydrolase
HRR27_RS08065	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HRR27_RS08080	ENOG4107ZT5	Thiol disulfide interchange protein
HRR27_RS08085	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HRR27_RS08095	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HRR27_RS08100	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HRR27_RS08110	ENOG4105DHP	deoxycytidine triphosphate deaminase
HRR27_RS08120	ENOG4107QZF	nitrite reductase NADPH large subunit
HRR27_RS08125	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HRR27_RS08130	ENOG4105D7T	ABC transporter
HRR27_RS08155	ENOG4105DKQ	ROK family
HRR27_RS08160	ENOG4105ED9	Protein of unknown function (DUF455)
HRR27_RS08175	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HRR27_RS08180	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HRR27_RS08185	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HRR27_RS08190	ENOG4107TT5	NLP P60 protein
HRR27_RS08195	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HRR27_RS08200	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HRR27_RS08205	ENOG4105CFG	Acts as a chaperone (By similarity)
HRR27_RS08210	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HRR27_RS08215	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HRR27_RS08220	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HRR27_RS08225	ENOG41090R7	Ferric uptake
HRR27_RS08240	ENOG4108Z1B	Cyclase dehydrase
HRR27_RS08250	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HRR27_RS08255	ENOG4105BZU	Histidine kinase
HRR27_RS08265	ENOG4105BZU	Histidine kinase
HRR27_RS08290	ENOG4105F8V	Hydrolase, tatD family
HRR27_RS08295	ENOG4107QRG	dna polymerase iii
HRR27_RS08300	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HRR27_RS08305	ENOG4105HHA	aminodeoxychorismate lyase
HRR27_RS08310	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HRR27_RS08320	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HRR27_RS08325	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HRR27_RS08330	ENOG4105CHR	reductase
HRR27_RS08335	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HRR27_RS08340	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HRR27_RS08345	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HRR27_RS08350	ENOG4105VGS	50s ribosomal protein l32
HRR27_RS08360	ENOG4108UHJ	MAF-like protein
HRR27_RS08365	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HRR27_RS08370	ENOG4105EI2	Pseudouridine synthase
HRR27_RS08375	ENOG4105C03	ribonuclease
HRR27_RS08380	ENOG4105KJF	protein tyrosine phosphatase
HRR27_RS08385	ENOG4105D3G	Pseudouridine synthase
HRR27_RS08400	ENOG4108KU3	Integrase
HRR27_RS08655	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HRR27_RS08730	ENOG4107U53	septum site-determining protein minD
HRR27_RS08740	ENOG4107SDU	Methyl-accepting chemotaxis
HRR27_RS08755	ENOG41088T4	Helicase IV
HRR27_RS08765	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRR27_RS08770	ENOG4105C8S	subunit m
HRR27_RS08780	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRR27_RS08785	ENOG4105DF2	NADH dehydrogenase subunit j
HRR27_RS08790	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRR27_RS08795	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HRR27_RS08800	ENOG4108IEH	NADH dehydrogenase subunit g
HRR27_RS08805	ENOG4107QIZ	NADH dehydrogenase
HRR27_RS08815	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRR27_RS08820	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HRR27_RS08825	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HRR27_RS08830	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HRR27_RS08840	ENOG4107EJC	Preprotein translocase subunit SecG
HRR27_RS08845	ENOG4105CP7	Triose-phosphate isomerase
HRR27_RS08850	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HRR27_RS08855	ENOG4105EEI	dihydropteroate synthase
HRR27_RS08860	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HRR27_RS08865	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HRR27_RS08870	ENOG4105HBR	Rna-binding protein
HRR27_RS08875	ENOG4105C28	cystathionine
HRR27_RS08880	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HRR27_RS08890	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HRR27_RS08895	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HRR27_RS08900	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HRR27_RS08910	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HRR27_RS08915	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HRR27_RS08920	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HRR27_RS08930	ENOG4105DR5	peptidase
HRR27_RS08935	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HRR27_RS08940	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HRR27_RS08945	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HRR27_RS08955	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HRR27_RS08965	ENOG4105DZ2	Transcriptional regulator
HRR27_RS08980	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HRR27_RS08990	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HRR27_RS08995	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HRR27_RS09010	ENOG4105DSE	periplasmic solute binding protein
HRR27_RS09015	ENOG4105DIK	(ABC) transporter
HRR27_RS09020	ENOG4105CC5	ABC transporter
HRR27_RS09025	ENOG4105CC5	ABC transporter
HRR27_RS09030	ENOG4107RPQ	ABC transporter
HRR27_RS09040	ENOG4105CHH	sulfate transporter
HRR27_RS09050	ENOG4105PWE	CRISPR-associated protein cas2
HRR27_RS09055	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
HRR27_RS09060	ENOG4108VWQ	crispr-associated protein
HRR27_RS09065	ENOG41060M0	Crispr-associated protein, cse4 family
HRR27_RS09100	ENOG4105NBK	UPF0345 protein
HRR27_RS09115	ENOG4105MYN	Zinc uptake regulation protein
HRR27_RS09120	ENOG4105D8G	Major Facilitator superfamily
HRR27_RS09125	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HRR27_RS09135	ENOG4108UHE	carbonic anhydrase
HRR27_RS09140	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HRR27_RS09145	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HRR27_RS09150	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HRR27_RS09160	ENOG4108UJV	acyl-CoA thioesterase i
HRR27_RS09165	ENOG4108I0Y	(ABC) transporter
HRR27_RS09170	ENOG4105CV6	ABC transporter, permease
HRR27_RS09205	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HRR27_RS09210	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HRR27_RS09215	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HRR27_RS09220	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HRR27_RS09225	ENOG41082NX	50s ribosomal protein l35
HRR27_RS09230	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HRR27_RS09235	ENOG4105C22	threonyL-tRNA synthetase
HRR27_RS09245	ENOG4107ZSV	Receptor
HRR27_RS09265	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HRR27_RS09285	ENOG4107S7U	Sulfide dehydrogenase
HRR27_RS09290	ENOG41090Y2	cytochrome C
HRR27_RS09300	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
HRR27_RS09305	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HRR27_RS09320	ENOG4108KMM	Diguanylate cyclase
HRR27_RS09325	ENOG4107TT2	Auxin Efflux Carrier
HRR27_RS09365	ENOG4105EXC	Acyl-transferase
HRR27_RS09370	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HRR27_RS09375	ENOG4108ZP8	Acetolactate synthase small subunit
HRR27_RS09380	ENOG4105C7K	acetolactate synthase
HRR27_RS09385	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HRR27_RS09390	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
HRR27_RS09395	ENOG41090A4	Pterin carbinolamine dehydratase
HRR27_RS09410	ENOG4105Z6S	cytochrome C, class I
HRR27_RS09415	ENOG4106RE7	Cytochrome
HRR27_RS09425	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HRR27_RS09430	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HRR27_RS09440	ENOG4105CUT	histidyl-tRNA synthetase
HRR27_RS09450	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HRR27_RS09455	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HRR27_RS09460	ENOG4108Z4V	iron-sulfur cluster assembly
HRR27_RS09465	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HRR27_RS09480	ENOG4105ECY	inositol monophosphatase
HRR27_RS09485	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HRR27_RS09495	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HRR27_RS09500	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HRR27_RS09505	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
HRR27_RS09515	ENOG4105ERG	peptidase m48, ste24p
HRR27_RS09535	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
HRR27_RS09545	ENOG4105C01	Dihydroxy-acid dehydratase
HRR27_RS09550	ENOG4107QZM	n-acetylglutamate synthase
HRR27_RS09560	ENOG4105M2J	Glutaredoxin
HRR27_RS09565	ENOG4105CAQ	asparagine synthetase
HRR27_RS09575	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HRR27_RS09580	ENOG4105EU8	FAD linked oxidase domain protein
HRR27_RS09585	ENOG4105CQB	FAD linked oxidase domain protein
HRR27_RS09590	ENOG4105C5R	Aminotransferase
HRR27_RS09595	ENOG4105EMU	Dehydrogenase
HRR27_RS09600	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
HRR27_RS09605	ENOG4108UB3	Thiamine monophosphate
HRR27_RS09610	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HRR27_RS09615	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HRR27_RS09620	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HRR27_RS09630	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HRR27_RS09635	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HRR27_RS09640	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HRR27_RS09645	ENOG4105CPF	Cell wall formation (By similarity)
HRR27_RS09650	ENOG4105DFU	Cell wall formation (By similarity)
HRR27_RS09660	ENOG4105C9B	Cysteine desulfurase
HRR27_RS09665	ENOG4105JRK	feS assembly protein SufD
HRR27_RS09670	ENOG4105C3K	feS assembly ATPase SufC
HRR27_RS09675	ENOG4105DIW	FeS assembly protein SUFB
HRR27_RS09685	ENOG4105NXV	High-affinity zinc uptake system protein
HRR27_RS09690	ENOG4105FDK	ABC transporter
HRR27_RS09695	ENOG4105FAV	ABC, transporter
HRR27_RS09700	ENOG4105C8Q	Methyl-accepting chemotaxis
HRR27_RS09705	ENOG4108IJ6	ABC transporter
HRR27_RS09710	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HRR27_RS09715	ENOG4105E0C	molybdate abc transporter
HRR27_RS09730	ENOG4105X1Q	TOBE domain protein
HRR27_RS09740	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HRR27_RS09760	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HRR27_RS09770	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HRR27_RS09775	ENOG4105CNI	cell division protein FtsW
HRR27_RS09780	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HRR27_RS09785	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HRR27_RS09790	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HRR27_RS09795	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HRR27_RS09810	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HRR27_RS09815	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HRR27_RS09845	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HRR27_RS09855	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HRR27_RS09860	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
HRR27_RS09865	ENOG41082RQ	UPF0102 protein
HRR27_RS09875	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HRR27_RS09880	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HRR27_RS09895	ENOG4105VEQ	Cold shock protein
HRR27_RS09910	ENOG4105C34	Pseudouridine synthase
HRR27_RS09925	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HRR27_RS09930	ENOG4105CPW	cytochrome b561
HRR27_RS09935	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HRR27_RS09940	ENOG4105D0M	Protease HtpX homolog
HRR27_RS09945	ENOG4108V0P	LemA family
HRR27_RS09955	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HRR27_RS09965	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HRR27_RS09970	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
HRR27_RS09990	ENOG4105KB2	stringent starvation protein b
HRR27_RS09995	ENOG4107MKT	Stringent starvation protein a
HRR27_RS10000	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HRR27_RS10005	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HRR27_RS10010	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HRR27_RS10025	ENOG4105CGY	Dna recombination protein
HRR27_RS10050	ENOG4107QHF	type ii secretion system protein e
HRR27_RS10100	ENOG4105C03	ribonuclease
HRR27_RS10105	ENOG4108Z03	MAF-like protein
HRR27_RS10120	ENOG4105CKK	Glycosyl transferase, family 2
HRR27_RS10150	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HRR27_RS10160	ENOG4105BZ1	(ABC) transporter
HRR27_RS10165	ENOG4105D1S	lipid A biosynthesis
HRR27_RS10170	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HRR27_RS10175	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HRR27_RS10185	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HRR27_RS10190	ENOG4105C8Y	Acetylornithine aminotransferase
HRR27_RS10195	ENOG4105DBV	ornithine carbamoyltransferase
HRR27_RS10240	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HRR27_RS10245	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HRR27_RS10250	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HRR27_RS10320	ENOG4105BZS	acriflavin resistance protein
HRR27_RS10335	ENOG4105DHZ	alpha beta
HRR27_RS10340	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HRR27_RS10370	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HRR27_RS10375	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HRR27_RS10380	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HRR27_RS10385	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HRR27_RS10390	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HRR27_RS10395	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HRR27_RS10400	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HRR27_RS10405	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HRR27_RS10425	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HRR27_RS10430	ENOG41060IM	Heme exporter protein
HRR27_RS10435	ENOG4105X3C	heme exporter protein
HRR27_RS10440	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HRR27_RS10445	ENOG4105DA4	cytochrome c-type biogenesis protein
HRR27_RS10450	ENOG4107QX9	Thiol disulfide interChange protein
HRR27_RS10455	ENOG4105KWW	Biogenesis protein
HRR27_RS10460	ENOG4108M1T	Cytochrome c-type biogenesis protein
HRR27_RS10465	ENOG4105CUW	cytochrome C-TYPE protein
HRR27_RS10470	ENOG4105MW3	Cytochrome
HRR27_RS10475	ENOG4107S7U	Sulfide dehydrogenase
HRR27_RS10480	ENOG4107S7U	Sulfide dehydrogenase
HRR27_RS10495	ENOG4107S7U	Sulfide dehydrogenase
HRR27_RS10500	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HRR27_RS10510	ENOG4105D4P	Coproporphyrinogen iii oxidase
HRR27_RS10515	ENOG4105BZU	Histidine kinase
HRR27_RS10520	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HRR27_RS10525	ENOG4105CVE	Lytic murein transglycosylase
HRR27_RS10540	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HRR27_RS10545	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HRR27_RS10550	ENOG4105DTN	riboflavin biosynthesis protein ribF
HRR27_RS10555	ENOG4105CJR	Integral membrane protein (MviN
HRR27_RS10570	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HRR27_RS10575	ENOG4107R0U	MotA TolQ exbB proton channel
HRR27_RS10580	ENOG4106VK6	Flagellar motor protein
HRR27_RS10585	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HRR27_RS10590	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HRR27_RS10595	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HRR27_RS10600	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HRR27_RS10615	ENOG4105C8T	Leucyl-tRNA synthetase
HRR27_RS10625	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HRR27_RS10630	ENOG4108JU5	Magnesium and cobalt efflux protein
HRR27_RS10635	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HRR27_RS10640	ENOG4105C9A	Phoh family
HRR27_RS10645	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HRR27_RS10655	ENOG4105BZU	Histidine kinase
HRR27_RS10660	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HRR27_RS10680	ENOG4108VAU	general secretion pathway protein G
HRR27_RS10690	ENOG4108Z9W	Outer membrane porin
HRR27_RS10695	ENOG4108UJD	30S ribosomal protein S9
HRR27_RS10700	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HRR27_RS10710	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRR27_RS10715	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HRR27_RS10720	ENOG4105KTH	gatB Yqey
HRR27_RS10725	ENOG4105VCC	30S ribosomal protein S21
HRR27_RS10730	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HRR27_RS10735	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HRR27_RS10740	ENOG4107ZVW	dihydroneopterin aldolase
HRR27_RS10760	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HRR27_RS10770	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HRR27_RS10775	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HRR27_RS10780	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HRR27_RS10790	ENOG4105BZU	Histidine kinase
HRR27_RS10795	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HRR27_RS10800	ENOG4105SYT	Methylenetetrahydrofolate reductase
HRR27_RS10805	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HRR27_RS10815	ENOG4105D7Z	glutathione synthase
HRR27_RS10820	ENOG41081YB	ApbE family
HRR27_RS10825	ENOG4108UJU	UPF0301 protein
HRR27_RS10830	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HRR27_RS10835	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HRR27_RS10840	ENOG4105CXT	aspartate transcarbamylase
HRR27_RS10845	ENOG4105CD3	dihydroorotase
HRR27_RS10860	ENOG4105CSR	polyphosphate kinase 2
HRR27_RS10865	ENOG4105DFA	alanine racemase domain protein
HRR27_RS10875	ENOG4105II7	pyrroline-5-carboxylate reductase
HRR27_RS10880	ENOG4108VIA	integral membrane protein
HRR27_RS10885	ENOG4105DWV	Homoserine O-trans-acetylase
HRR27_RS10900	ENOG4105CE1	Ferrous iron transport protein b
HRR27_RS10915	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
HRR27_RS10920	ENOG4106CJB	Phospholipase Carboxylesterase
HRR27_RS10930	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HRR27_RS10945	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HRR27_RS10955	ENOG4105BZU	Histidine kinase
HRR27_RS10960	ENOG4108XDN	Transcriptional regulator
HRR27_RS10965	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HRR27_RS10995	ENOG4107FW0	short-chain dehydrogenase reductase
HRR27_RS11005	ENOG4105CT4	transporter
HRR27_RS11010	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HRR27_RS11015	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HRR27_RS11020	ENOG4105BZU	Histidine kinase
HRR27_RS11060	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HRR27_RS11065	ENOG4105BZN	citrate synthase
HRR27_RS11070	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HRR27_RS11075	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HRR27_RS11080	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HRR27_RS11085	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HRR27_RS11095	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HRR27_RS11100	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HRR27_RS11105	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HRR27_RS11110	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HRR27_RS11115	ENOG4105K46	50S ribosomal protein l27
HRR27_RS11120	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HRR27_RS11125	ENOG4105EAH	synthase
HRR27_RS11135	ENOG4108UUM	single-stranded DNA-binding protein
HRR27_RS11140	ENOG4107RDB	Major Facilitator
HRR27_RS11150	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HRR27_RS11160	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HRR27_RS11165	ENOG4105CUZ	uba thif-type nad fad binding protein
HRR27_RS11175	ENOG4108ZT0	50S ribosomal protein l17
HRR27_RS11180	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HRR27_RS11185	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HRR27_RS11190	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HRR27_RS11195	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HRR27_RS11200	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HRR27_RS11205	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HRR27_RS11210	ENOG4105VPB	50S ribosomal protein L30
HRR27_RS11215	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HRR27_RS11220	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HRR27_RS11225	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HRR27_RS11230	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HRR27_RS11235	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HRR27_RS11240	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HRR27_RS11245	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HRR27_RS11250	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HRR27_RS11255	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HRR27_RS11260	ENOG41083MP	50s ribosomal protein l29
HRR27_RS11265	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HRR27_RS11270	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HRR27_RS11275	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HRR27_RS11280	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HRR27_RS11285	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HRR27_RS11290	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HRR27_RS11295	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HRR27_RS11300	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HRR27_RS11305	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HRR27_RS11310	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HRR27_RS11315	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HRR27_RS11320	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HRR27_RS11325	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HRR27_RS11330	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HRR27_RS11335	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HRR27_RS11340	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HRR27_RS11345	ENOG4108VZM	50s ribosomal protein L10
HRR27_RS11350	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HRR27_RS11355	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HRR27_RS11360	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HRR27_RS11365	ENOG4105PM1	preprotein translocase subunit SecE
HRR27_RS11375	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HRR27_RS11400	ENOG4105DR9	pseudouridine synthase
HRR27_RS11405	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HRR27_RS11435	ENOG4105CD3	dihydroorotase
HRR27_RS11440	ENOG4105BZU	Histidine kinase
HRR27_RS11445	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HRR27_RS11455	ENOG4105C9X	ppx gppa phosphatase
HRR27_RS11460	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HRR27_RS11475	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HRR27_RS11480	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HRR27_RS11485	ENOG4105CDV	Ompa motb domain protein
HRR27_RS11495	ENOG4105D64	Mechanosensitive ion channel
HRR27_RS11500	ENOG4105CAS	nag kinase
HRR27_RS11505	ENOG4108VPT	UPF0234 protein
HRR27_RS11535	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HRR27_RS11540	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HRR27_RS11550	ENOG4107T8V	it plays a direct role in the translocation of protons across the membrane (By similarity)
HRR27_RS11560	ENOG4108Q71	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
HRR27_RS11575	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HRR27_RS11585	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HRR27_RS11590	ENOG4105BZU	Histidine kinase
HRR27_RS11600	ENOG4105EW6	flavin reductase domain protein, FMN-binding
HRR27_RS11605	ENOG4107Y2X	deaminase
HRR27_RS11615	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HRR27_RS11625	ENOG4105C8Q	Methyl-accepting chemotaxis
HRR27_RS11630	ENOG4107S7U	Sulfide dehydrogenase
HRR27_RS11645	ENOG4105W5Q	DNA repair protein (RadC
HRR27_RS11665	ENOG4105KDC	50s ribosomal protein l28
HRR27_RS11670	ENOG4105W0E	50S ribosomal protein L33
HRR27_RS11685	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HRR27_RS11695	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HRR27_RS11700	ENOG4105E0C	molybdate abc transporter
HRR27_RS11705	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HRR27_RS11710	ENOG4105F4R	Transcriptional regulator mode
HRR27_RS11725	ENOG4105D3R	alkyl hydroperoxide reductase
HRR27_RS11730	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HRR27_RS11735	ENOG4106H78	methyltransferase
HRR27_RS11745	ENOG4105BZU	Histidine kinase
HRR27_RS11765	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HRR27_RS11785	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HRR27_RS11795	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HRR27_RS11830	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HRR27_RS11835	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
HRR27_RS11840	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HRR27_RS11845	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HRR27_RS11850	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HRR27_RS11855	ENOG4105VW4	glutaredoxin 3
HRR27_RS11865	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HRR27_RS11870	ENOG4105CBC	glutamate synthase
HRR27_RS11875	ENOG4105BZ8	glutamate synthase
HRR27_RS11890	ENOG4105C5I	Dehydrogenase
HRR27_RS11900	ENOG4105CH5	extracellular solute-binding protein, family 7
HRR27_RS11905	ENOG4105C8Q	Methyl-accepting chemotaxis
HRR27_RS11920	ENOG4105D05	Receptor
HRR27_RS11930	ENOG4107QX9	Thiol disulfide interChange protein
HRR27_RS11940	ENOG41083J0	(ABC) transporter
HRR27_RS11945	ENOG4105C4R	Atp-dependent dna helicase
HRR27_RS11950	ENOG4105K63	Thioredoxin
HRR27_RS11955	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HRR27_RS11960	ENOG4105NRA	50s ribosomal protein l31 type b
HRR27_RS11970	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HRR27_RS11980	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HRR27_RS11985	ENOG4105CEN	a g-specific adenine glycosylase
HRR27_RS11990	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HRR27_RS12000	ENOG4105CSA	Coproporphyrinogen iii oxidase
HRR27_RS12005	ENOG4105C2C	drug resistance transporter, Bcr CflA
HRR27_RS12010	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HRR27_RS12015	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HRR27_RS12020	ENOG4105DSJ	YicC domain protein
HRR27_RS12095	ENOG4108JQC	penicillin-binding protein 1A
HRR27_RS12105	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HRR27_RS12130	ENOG4105EB3	Histidine kinase
HRR27_RS12135	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HRR27_RS12140	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HRR27_RS12145	ENOG4105BZS	acriflavin resistance protein
HRR27_RS12150	ENOG4105BZU	Histidine kinase
HRR27_RS12175	ENOG4105E5H	Transposase
HRR27_RS12210	ENOG4105CTK	cobaltochelatase, cobn subunit
HRR27_RS12215	ENOG4105D05	Receptor
HRR27_RS12220	ENOG4105CTK	cobaltochelatase, cobn subunit
HRR27_RS12235	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HRR27_RS12240	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HRR27_RS12250	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HRR27_RS12255	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HRR27_RS12265	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HRR27_RS12280	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HRR27_RS12285	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HRR27_RS12290	ENOG4105BZU	Histidine kinase
HRR27_RS12300	ENOG4105EUB	pirin domain protein
HRR27_RS12305	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HRR27_RS12310	ENOG4105EXG	Transcriptional regulator
HRR27_RS12315	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HRR27_RS12315	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HRR27_RS12380	ENOG4105C8Q	Methyl-accepting chemotaxis
HRR27_RS12410	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HRR27_RS12435	ENOG4105KNY	Microcompartments protein
HRR27_RS12440	ENOG4105KNY	Microcompartments protein
HRR27_RS12445	ENOG4105KNY	Microcompartments protein
HRR27_RS12475	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
HRR27_RS12485	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HRR27_RS12495	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HRR27_RS12500	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HRR27_RS12505	ENOG4105C87	Aminotransferase class I and II
HRR27_RS12520	ENOG4105DSB	aldose 1-epimerase
HRR27_RS12525	ENOG4105D49	3-dehydroquinate synthase
HRR27_RS12530	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HRR27_RS12535	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HRR27_RS12540	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HRR27_RS12545	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HRR27_RS12550	ENOG4105KME	endoribonuclease L-psp
HRR27_RS12555	ENOG4105DQF	Hydrolase
HRR27_RS12560	ENOG4105CB5	ATP-dependent DNA helicase recG
HRR27_RS12565	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HRR27_RS12580	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HRR27_RS12590	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HRR27_RS12595	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HRR27_RS12600	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HRR27_RS12605	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HRR27_RS12610	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HRR27_RS12615	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HRR27_RS12620	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HRR27_RS12625	ENOG41081A3	ATP synthase f0, c subunit
HRR27_RS12630	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HRR27_RS12650	ENOG4107QJE	Chromosome Partitioning Protein
HRR27_RS12655	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HRR27_RS12660	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HRR27_RS12675	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HRR27_RS12710	ENOG4105DGU	Histone deacetylase
HRR27_RS12715	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HRR27_RS12720	ENOG4105BZS	acriflavin resistance protein
HRR27_RS12735	ENOG4105C8Q	Methyl-accepting chemotaxis
HRR27_RS12745	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HRR27_RS12750	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HRR27_RS12760	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HRR27_RS12765	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HRR27_RS12770	ENOG4105VG0	50S ribosomal protein l34