locus-tag	class	description
BVH73_RS00020	COG0330	HflC and HflK could
BVH73_RS00025	COG2833	Protein of unknown function (DUF455)
BVH73_RS00045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVH73_RS00050	COG2095	MarC family integral membrane protein
BVH73_RS00055	COG4974	Belongs to the 'phage' integrase family
BVH73_RS00065	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BVH73_RS00070	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVH73_RS00075	COG1940	carbohydrate kinase activity
BVH73_RS00080	COG5001	Diguanylate cyclase
BVH73_RS00085	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BVH73_RS00095	COG1196	nuclear chromosome segregation
BVH73_RS00100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BVH73_RS00105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BVH73_RS00130	COG1216	Glycosyl transferase, family 2
BVH73_RS00145	COG0438	transferase activity, transferring glycosyl groups
BVH73_RS00155	COG0438	transferase activity, transferring glycosyl groups
BVH73_RS00160	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BVH73_RS00165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVH73_RS00170	COG0546	phosphoglycolate phosphatase activity
BVH73_RS00180	COG2963	transposase activity
BVH73_RS00200	COG0776	regulation of translation
BVH73_RS00205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVH73_RS00205	COG0072	phenylalanine-tRNA ligase activity
BVH73_RS00210	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BVH73_RS00215	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BVH73_RS00225	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BVH73_RS00230	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BVH73_RS00240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVH73_RS00270	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BVH73_RS00275	COG0586	Pfam SNARE associated Golgi protein
BVH73_RS00280	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BVH73_RS00285	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BVH73_RS00295	COG2197	response regulator
BVH73_RS00305	COG0840	transmembrane signaling receptor activity
BVH73_RS00330	COG5001	Diguanylate cyclase
BVH73_RS00330	COG5002	protein histidine kinase activity
BVH73_RS00355	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BVH73_RS00360	COG2201	protein-glutamate methylesterase activity
BVH73_RS00415	COG1677	Flagellar hook-basal body complex protein FliE
BVH73_RS00445	COG1516	flagellar protein fliS
BVH73_RS00450	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BVH73_RS00505	COG1815	bacterial-type flagellum-dependent cell motility
BVH73_RS00510	COG1558	bacterial-type flagellum-dependent cell motility
BVH73_RS00525	COG4787	bacterial-type flagellum-dependent cell motility
BVH73_RS00535	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BVH73_RS00540	COG1706	bacterial-type flagellum-dependent cell motility
BVH73_RS00555	COG1256	bacterial-type flagellum assembly
BVH73_RS00575	COG1216	Glycosyl transferase, family 2
BVH73_RS00575	COG0438	transferase activity, transferring glycosyl groups
BVH73_RS00580	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BVH73_RS00590	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BVH73_RS00625	COG0643	Histidine kinase
BVH73_RS00625	COG2198	Histidine kinase
BVH73_RS00645	COG0840	transmembrane signaling receptor activity
BVH73_RS00650	COG0784	Response regulator, receiver
BVH73_RS00650	COG0835	chemotaxis
BVH73_RS00655	COG0840	transmembrane signaling receptor activity
BVH73_RS00675	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVH73_RS00695	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BVH73_RS00700	COG1191	sigma factor activity
BVH73_RS00715	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVH73_RS00730	COG1987	bacterial-type flagellum assembly
BVH73_RS00740	COG3190	flagellar
BVH73_RS00770	COG3243	poly(R)-hydroxyalkanoic acid synthase
BVH73_RS00780	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BVH73_RS00795	COG1850	ribulose-bisphosphate carboxylase activity
BVH73_RS00815	COG0300	oxidoreductase activity
BVH73_RS00820	COG0582	viral genome integration into host DNA
BVH73_RS00910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVH73_RS00925	COG0473	3-isopropylmalate dehydrogenase activity
BVH73_RS00960	COG0322	excinuclease ABC activity
BVH73_RS00965	COG1573	uracil-dna glycosylase
BVH73_RS00975	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BVH73_RS00995	COG2030	dehydratase
BVH73_RS01000	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BVH73_RS01015	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BVH73_RS01020	COG1523	belongs to the glycosyl hydrolase 13 family
BVH73_RS01025	COG0033	Phosphoglucomutase
BVH73_RS01035	COG0297	glycogen (starch) synthase activity
BVH73_RS01040	COG0058	SHG alpha-glucan phosphorylase activity
BVH73_RS01045	COG0166	Belongs to the GPI family
BVH73_RS01085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BVH73_RS01100	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BVH73_RS01105	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BVH73_RS01110	COG2271	Major facilitator Superfamily
BVH73_RS01135	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BVH73_RS01140	COG0802	atpase or kinase
BVH73_RS01145	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVH73_RS01150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BVH73_RS01170	COG0425	Belongs to the sulfur carrier protein TusA family
BVH73_RS01190	COG1280	lysine exporter protein (LysE YggA)
BVH73_RS01205	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVH73_RS01210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BVH73_RS01235	COG0723	plastoquinol--plastocyanin reductase activity
BVH73_RS01240	COG0243	molybdopterin cofactor binding
BVH73_RS01245	COG4654	Cytochrome c, class I
BVH73_RS01285	COG1393	Belongs to the ArsC family
BVH73_RS01310	COG3706	GGDEF domain
BVH73_RS01335	COG0181	hydroxymethylbilane synthase activity
BVH73_RS01340	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BVH73_RS01345	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVH73_RS01360	COG2133	pyrroloquinoline quinone binding
BVH73_RS01365	COG0556	nucleotide-excision repair
BVH73_RS01385	COG2878	Part of a membrane complex involved in electron transport
BVH73_RS01390	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BVH73_RS01400	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BVH73_RS01405	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BVH73_RS01410	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BVH73_RS01440	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BVH73_RS01445	COG0525	valine-tRNA ligase activity
BVH73_RS01460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BVH73_RS01465	COG0287	Prephenate dehydrogenase
BVH73_RS01470	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BVH73_RS01480	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BVH73_RS01495	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVH73_RS01505	COG0557	exoribonuclease II activity
BVH73_RS01525	COG0667	Aldo Keto reductase
BVH73_RS01560	COG2814	Major facilitator Superfamily
BVH73_RS01565	COG0667	Aldo Keto reductase
BVH73_RS01570	COG0583	DNA-binding transcription factor activity
BVH73_RS01580	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVH73_RS01590	COG0277	FAD linked oxidase domain protein
BVH73_RS01600	COG2226	methyltransferase
BVH73_RS01605	COG0683	leucine binding
BVH73_RS01610	COG1522	sequence-specific DNA binding
BVH73_RS01620	COG0431	NADPH-dependent FMN reductase
BVH73_RS01645	COG4680	protein conserved in bacteria
BVH73_RS01670	COG0477	Major facilitator Superfamily
BVH73_RS01675	COG0583	DNA-binding transcription factor activity
BVH73_RS01680	COG3328	transposase activity
BVH73_RS01685	COG2091	lysine biosynthetic process via aminoadipic acid
BVH73_RS01700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVH73_RS01700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVH73_RS01700	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BVH73_RS01700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVH73_RS01700	COG3321	synthase
BVH73_RS01700	COG3321	synthase
BVH73_RS01700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVH73_RS01700	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
BVH73_RS01705	COG0318	PFAM AMP-dependent synthetase and ligase
BVH73_RS01705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVH73_RS01705	COG1028	Short-chain dehydrogenase reductase Sdr
BVH73_RS01705	COG0300	oxidoreductase activity
BVH73_RS01705	COG3321	synthase
BVH73_RS01725	COG3916	Acyl-homoserine-lactone synthase
BVH73_RS01735	COG2197	response regulator
BVH73_RS01740	COG1484	DNA-dependent DNA replication
BVH73_RS01745	COG4584	PFAM Integrase catalytic
BVH73_RS01750	COG2197	response regulator
BVH73_RS01770	COG3451	type IV secretory pathway VirB4
BVH73_RS01840	COG4962	Type ii secretion system protein e
BVH73_RS01850	COG1111	helicase
BVH73_RS01850	COG1205	dead DEAH box helicase
BVH73_RS01860	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BVH73_RS01885	COG1309	transcriptional regulator
BVH73_RS01890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVH73_RS01895	COG0583	DNA-binding transcription factor activity
BVH73_RS01965	COG1475	DNA binding
BVH73_RS02020	COG0582	viral genome integration into host DNA
BVH73_RS02060	COG3039	Transposase
BVH73_RS02085	COG0582	viral genome integration into host DNA
BVH73_RS02095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVH73_RS02115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BVH73_RS02120	COG1902	pentaerythritol trinitrate reductase activity
BVH73_RS02140	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVH73_RS02150	COG0730	response to heat
BVH73_RS02155	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVH73_RS02195	COG3409	Peptidoglycan-binding domain 1 protein
BVH73_RS02195	COG3267	Type II secretory pathway component ExeA
BVH73_RS02205	COG0489	protein tyrosine kinase activity
BVH73_RS02210	COG3321	synthase
BVH73_RS02210	COG1028	Short-chain dehydrogenase reductase Sdr
BVH73_RS02210	COG0318	PFAM AMP-dependent synthetase and ligase
BVH73_RS02210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVH73_RS02210	COG0300	oxidoreductase activity
BVH73_RS02225	COG0328	RNA-DNA hybrid ribonuclease activity
BVH73_RS02230	COG2226	methyltransferase
BVH73_RS02235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVH73_RS02240	COG0741	lytic transglycosylase activity
BVH73_RS02240	COG1388	LysM domain
BVH73_RS02245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BVH73_RS02270	COG0314	molybdopterin synthase activity
BVH73_RS02280	COG0303	'Molybdopterin
BVH73_RS02285	COG1763	Mo-molybdopterin cofactor biosynthetic process
BVH73_RS02300	COG0436	Aminotransferase
BVH73_RS02310	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BVH73_RS02315	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BVH73_RS02320	COG0305	Participates in initiation and elongation during chromosome replication
BVH73_RS02325	COG0359	binds to the 23S rRNA
BVH73_RS02330	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BVH73_RS02340	COG0360	Binds together with S18 to 16S ribosomal RNA
BVH73_RS02350	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BVH73_RS02360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVH73_RS02365	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BVH73_RS02375	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVH73_RS02380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVH73_RS02385	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVH73_RS02400	COG0750	zinc metalloprotease
BVH73_RS02405	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BVH73_RS02410	COG0575	Belongs to the CDS family
BVH73_RS02415	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BVH73_RS02420	COG0233	cytoplasmic translational termination
BVH73_RS02425	COG0528	UMP kinase activity
BVH73_RS02430	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BVH73_RS02435	COG0052	Belongs to the universal ribosomal protein uS2 family
BVH73_RS02445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVH73_RS02450	COG4181	ATPase activity
BVH73_RS02460	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BVH73_RS02465	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVH73_RS02475	COG0438	transferase activity, transferring glycosyl groups
BVH73_RS02480	COG1045	serine acetyltransferase
BVH73_RS02505	COG0583	DNA-binding transcription factor activity
BVH73_RS02510	COG4221	oxidoreductase activity
BVH73_RS02525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVH73_RS02530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BVH73_RS02535	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BVH73_RS02550	COG1561	YicC-like family, N-terminal region
BVH73_RS02555	COG0194	GDP metabolic process
BVH73_RS02560	COG1758	RNA polymerase activity
BVH73_RS02565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BVH73_RS02575	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BVH73_RS02580	COG1074	ATP-dependent DNA helicase activity
BVH73_RS02585	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BVH73_RS02605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BVH73_RS02610	COG0367	asparagine synthase
BVH73_RS02615	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BVH73_RS02620	COG1083	cytidylyl-transferase
BVH73_RS02625	COG2089	acid synthase
BVH73_RS02685	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BVH73_RS02705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVH73_RS02715	COG0659	secondary active sulfate transmembrane transporter activity
BVH73_RS02720	COG1136	(ABC) transporter
BVH73_RS02725	COG0850	regulation of cytokinetic process
BVH73_RS02735	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BVH73_RS02750	COG1522	sequence-specific DNA binding
BVH73_RS02765	COG2814	Major facilitator Superfamily
BVH73_RS02795	COG1556	Lactate utilization protein
BVH73_RS02840	COG2084	Dehydrogenase
BVH73_RS02845	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BVH73_RS02850	COG2823	Periplasmic or secreted lipoprotein
BVH73_RS02855	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BVH73_RS02860	COG0792	nuclease activity
BVH73_RS02905	COG0387	Pfam Sodium calcium exchanger
BVH73_RS02930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVH73_RS02960	COG3245	cytochrome
BVH73_RS02970	COG0582	viral genome integration into host DNA
BVH73_RS03005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVH73_RS03040	COG3177	Filamentation induced by cAMP protein fic
BVH73_RS03050	COG4584	PFAM Integrase catalytic
BVH73_RS03055	COG1484	DNA-dependent DNA replication
BVH73_RS03120	COG3328	transposase activity
BVH73_RS03155	COG0582	viral genome integration into host DNA
BVH73_RS03165	COG0527	aspartate kinase activity
BVH73_RS03170	COG0037	tRNA processing
BVH73_RS03185	COG0215	cysteine-tRNA ligase activity
BVH73_RS03200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BVH73_RS03250	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BVH73_RS03255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVH73_RS03260	COG0670	Belongs to the BI1 family
BVH73_RS03265	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVH73_RS03285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BVH73_RS03290	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BVH73_RS03310	COG1183	phosphatidylcholine synthase activity
BVH73_RS03315	COG0688	phosphatidylethanolamine metabolic process
BVH73_RS03320	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BVH73_RS03325	COG0440	acetolactate synthase activity
BVH73_RS03330	COG0028	Belongs to the TPP enzyme family
BVH73_RS03370	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BVH73_RS03375	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BVH73_RS03380	COG0312	modulator of DNA gyrase
BVH73_RS03385	COG3028	Belongs to the UPF0307 family
BVH73_RS03390	COG0521	Mo-molybdopterin cofactor biosynthetic process
BVH73_RS03400	COG0667	Aldo Keto reductase
BVH73_RS03405	COG3300	MHYT domain
BVH73_RS03405	COG5001	Diguanylate cyclase
BVH73_RS03410	COG1609	Transcriptional regulator
BVH73_RS03415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BVH73_RS03415	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVH73_RS03420	COG1105	Belongs to the carbohydrate kinase PfkB family
BVH73_RS03425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVH73_RS03425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BVH73_RS03430	COG0531	amino acid
BVH73_RS03435	COG1611	Belongs to the LOG family
BVH73_RS03445	COG0514	ATP-dependent DNA helicase (RecQ)
BVH73_RS03465	COG0583	DNA-binding transcription factor activity
BVH73_RS03475	COG1703	isobutyryl-CoA mutase activity
BVH73_RS03475	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BVH73_RS03475	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BVH73_RS03490	COG0723	plastoquinol--plastocyanin reductase activity
BVH73_RS03495	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BVH73_RS03500	COG2857	Cytochrome c1
BVH73_RS03505	COG0625	glutathione transferase activity
BVH73_RS03510	COG2969	positive regulation of protein catabolic process
BVH73_RS03635	COG2226	methyltransferase
BVH73_RS03650	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BVH73_RS03655	COG0656	L-ascorbic acid biosynthetic process
BVH73_RS03665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BVH73_RS03670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BVH73_RS03675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVH73_RS03680	COG0805	protein transport
BVH73_RS03685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVH73_RS03690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVH73_RS03705	COG0140	phosphoribosyl-ATP diphosphatase activity
BVH73_RS03705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BVH73_RS03710	COG0107	imidazoleglycerol-phosphate synthase activity
BVH73_RS03715	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BVH73_RS03725	COG0131	Imidazoleglycerol-phosphate dehydratase
BVH73_RS03730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BVH73_RS03735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BVH73_RS03740	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BVH73_RS03745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVH73_RS03755	COG0842	Transport permease protein
BVH73_RS03760	COG1131	(ABC) transporter
BVH73_RS03775	COG2853	Lipoprotein
BVH73_RS03780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BVH73_RS03785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BVH73_RS03790	COG1127	ABC transporter
BVH73_RS03835	COG1937	Protein conserved in bacteria
BVH73_RS03855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVH73_RS03880	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVH73_RS03900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVH73_RS03915	COG2358	TRAP transporter, solute receptor (TAXI family
BVH73_RS03930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BVH73_RS03935	COG4783	chaperone-mediated protein folding
BVH73_RS03940	COG3307	-O-antigen
BVH73_RS03960	COG0469	pyruvate kinase activity
BVH73_RS03970	COG0631	protein serine/threonine phosphatase activity
BVH73_RS03975	COG0861	Integral membrane protein TerC family
BVH73_RS03980	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BVH73_RS03985	COG0045	succinate-CoA ligase (ADP-forming) activity
BVH73_RS03995	COG2137	regulation of response to DNA damage stimulus
BVH73_RS04000	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BVH73_RS04015	COG0009	L-threonylcarbamoyladenylate synthase
BVH73_RS04020	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BVH73_RS04030	COG3118	belongs to the thioredoxin family
BVH73_RS04035	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BVH73_RS04045	COG0072	phenylalanine-tRNA ligase activity
BVH73_RS04045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVH73_RS04050	COG1280	lysine exporter protein (LysE YggA)
BVH73_RS04055	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BVH73_RS04060	COG0783	Belongs to the Dps family
BVH73_RS04065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BVH73_RS04075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVH73_RS04080	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BVH73_RS04095	COG2850	peptidyl-arginine hydroxylation
BVH73_RS04100	COG1047	Peptidyl-prolyl cis-trans
BVH73_RS04110	COG0756	dUTP diphosphatase activity
BVH73_RS04115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BVH73_RS04125	COG1012	belongs to the aldehyde dehydrogenase family
BVH73_RS04160	COG0123	including yeast histone deacetylase and acetoin utilization protein
BVH73_RS04165	COG0714	Associated with various cellular activities
BVH73_RS04185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BVH73_RS04210	COG2900	Belongs to the SlyX family
BVH73_RS04215	COG2921	Belongs to the UPF0250 family
BVH73_RS04220	COG2132	Multicopper oxidase
BVH73_RS04255	COG0714	Associated with various cellular activities
BVH73_RS04260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVH73_RS04265	COG2814	Major facilitator Superfamily
BVH73_RS04270	COG3794	PFAM blue (type 1) copper domain protein
BVH73_RS04300	COG0742	ribosomal rna small subunit methyltransferase
BVH73_RS04305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BVH73_RS04310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BVH73_RS04330	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BVH73_RS04335	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BVH73_RS04340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVH73_RS04345	COG0588	phosphoglycerate mutase activity
BVH73_RS04350	COG0793	Belongs to the peptidase S41A family
BVH73_RS04355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BVH73_RS04360	COG0300	oxidoreductase activity
BVH73_RS04365	COG0640	Transcriptional regulator
BVH73_RS04380	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BVH73_RS04410	COG1280	lysine exporter protein (LysE YggA)
BVH73_RS04430	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BVH73_RS04435	COG0741	lytic transglycosylase activity
BVH73_RS04440	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BVH73_RS04450	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVH73_RS04470	COG0259	pyridoxamine-phosphate oxidase activity
BVH73_RS04500	COG3220	belongs to the UPF0276 family
BVH73_RS04510	COG1595	DNA-templated transcription, initiation
BVH73_RS04530	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BVH73_RS04540	COG0067	glutamate synthase
BVH73_RS04540	COG0069	glutamate synthase activity
BVH73_RS04540	COG0070	glutamate synthase
BVH73_RS04560	COG0513	Belongs to the DEAD box helicase family
BVH73_RS04580	COG0625	glutathione transferase activity
BVH73_RS04585	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVH73_RS04590	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BVH73_RS04595	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BVH73_RS04625	COG0642	Histidine kinase
BVH73_RS04630	COG1028	Short-chain dehydrogenase reductase Sdr
BVH73_RS04645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BVH73_RS04650	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BVH73_RS04660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BVH73_RS04695	COG1965	Belongs to the frataxin family
BVH73_RS04710	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BVH73_RS04715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BVH73_RS04720	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVH73_RS04725	COG1333	cytochrome c biogenesis protein
BVH73_RS04740	COG1752	Esterase of the alpha-beta hydrolase superfamily
BVH73_RS04755	COG0459	protein refolding
BVH73_RS04760	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BVH73_RS04815	COG0583	DNA-binding transcription factor activity
BVH73_RS04840	COG0277	FAD linked oxidase domain protein
BVH73_RS04845	COG2096	Adenosyltransferase
BVH73_RS04860	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVH73_RS04865	COG1538	Outer membrane efflux protein
BVH73_RS04875	COG3720	iron ion transport
BVH73_RS04880	COG4558	Periplasmic binding protein
BVH73_RS04885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVH73_RS04890	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BVH73_RS04920	COG0406	alpha-ribazole phosphatase activity
BVH73_RS04925	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BVH73_RS04935	COG1283	sodium-dependent phosphate transmembrane transporter activity
BVH73_RS04955	COG0277	FAD linked oxidase domain protein
BVH73_RS04960	COG0277	FAD linked oxidase domain protein
BVH73_RS04965	COG0247	lactate metabolic process
BVH73_RS04970	COG0386	Belongs to the glutathione peroxidase family
BVH73_RS04980	COG3300	MHYT domain
BVH73_RS04980	COG5001	Diguanylate cyclase
BVH73_RS04985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVH73_RS04990	COG0668	transmembrane transport
BVH73_RS04995	COG0477	Major facilitator Superfamily
BVH73_RS05000	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVH73_RS05015	COG4302	ethanolamine ammonia-lyase activity
BVH73_RS05020	COG4303	Ethanolamine ammonia lyase large subunit
BVH73_RS05035	COG4178	(ABC) transporter
BVH73_RS05095	COG2852	Protein conserved in bacteria
BVH73_RS05110	COG4636	protein conserved in cyanobacteria
BVH73_RS05115	COG1473	amidohydrolase
BVH73_RS05170	COG0438	transferase activity, transferring glycosyl groups
BVH73_RS05190	COG4636	protein conserved in cyanobacteria
BVH73_RS05195	COG4636	protein conserved in cyanobacteria
BVH73_RS05215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVH73_RS05220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BVH73_RS05230	COG4689	acetoacetate decarboxylase
BVH73_RS05260	COG1522	sequence-specific DNA binding
BVH73_RS05280	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BVH73_RS05285	COG4941	Belongs to the sigma-70 factor family
BVH73_RS05300	COG3795	YCII-related domain
BVH73_RS05305	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BVH73_RS05335	COG2205	protein histidine kinase activity
BVH73_RS05335	COG0784	Response regulator, receiver
BVH73_RS05335	COG2198	Histidine kinase
BVH73_RS05345	COG2814	Major facilitator Superfamily
BVH73_RS05370	COG2132	Multicopper oxidase
BVH73_RS05380	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVH73_RS05390	COG0477	Major facilitator Superfamily
BVH73_RS05395	COG1335	isochorismatase
BVH73_RS05400	COG1846	Transcriptional regulator
BVH73_RS05405	COG5001	Diguanylate cyclase
BVH73_RS05405	COG3300	MHYT domain
BVH73_RS05410	COG3300	MHYT domain
BVH73_RS05410	COG5001	Diguanylate cyclase
BVH73_RS05415	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BVH73_RS05425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BVH73_RS05430	COG3448	diguanylate cyclase activity
BVH73_RS05430	COG4175	Glycine betaine
BVH73_RS05445	COG2113	Glycine betaine
BVH73_RS05470	COG1573	uracil-dna glycosylase
BVH73_RS05485	COG1968	undecaprenyl-diphosphatase activity
BVH73_RS05495	COG3275	phosphorelay sensor kinase activity
BVH73_RS05500	COG0165	Argininosuccinate lyase
BVH73_RS05505	COG0717	Belongs to the dCTP deaminase family
BVH73_RS05510	COG1872	DUF167
BVH73_RS05525	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVH73_RS05525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BVH73_RS05530	COG3023	N-Acetylmuramoyl-L-alanine amidase
BVH73_RS05555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BVH73_RS05560	COG0741	lytic transglycosylase activity
BVH73_RS05565	COG0442	prolyl-tRNA aminoacylation
BVH73_RS05570	COG0494	nUDIX hydrolase
BVH73_RS05580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BVH73_RS05585	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BVH73_RS05590	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BVH73_RS05595	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BVH73_RS05600	COG0142	geranyltranstransferase activity
BVH73_RS05625	COG0237	dephospho-CoA kinase activity
BVH73_RS05635	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BVH73_RS05640	COG0494	nUDIX hydrolase
BVH73_RS05650	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BVH73_RS05655	COG0653	protein targeting
BVH73_RS05665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BVH73_RS05670	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BVH73_RS05680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BVH73_RS05685	COG1181	Belongs to the D-alanine--D-alanine ligase family
BVH73_RS05690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVH73_RS05695	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BVH73_RS05700	COG0772	Belongs to the SEDS family
BVH73_RS05705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BVH73_RS05710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVH73_RS05715	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BVH73_RS05730	COG0275	rRNA processing
BVH73_RS05735	COG2001	Belongs to the MraZ family
BVH73_RS05750	COG0418	dihydroorotase activity
BVH73_RS05755	COG1126	abc transporter atp-binding protein
BVH73_RS05760	COG0765	amino acid transport
BVH73_RS05765	COG0765	amino acid transport
BVH73_RS05770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVH73_RS05775	COG5265	(ABC) transporter
BVH73_RS05785	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BVH73_RS05790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVH73_RS05800	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BVH73_RS05815	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BVH73_RS05820	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BVH73_RS05825	COG1194	a g-specific adenine glycosylase
BVH73_RS05860	COG1254	Belongs to the acylphosphatase family
BVH73_RS05870	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVH73_RS05880	COG0488	(ABC) transporter
BVH73_RS05885	COG0513	Belongs to the DEAD box helicase family
BVH73_RS05900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BVH73_RS05910	COG0477	Major facilitator Superfamily
BVH73_RS05910	COG2814	Major facilitator Superfamily
BVH73_RS05915	COG2199	diguanylate cyclase activity
BVH73_RS05915	COG2200	EAL domain
BVH73_RS05925	COG1024	Enoyl-CoA hydratase
BVH73_RS05940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVH73_RS05945	COG1686	Belongs to the peptidase S11 family
BVH73_RS05965	COG1981	membrane
BVH73_RS06005	COG1054	Belongs to the UPF0176 family
BVH73_RS06045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVH73_RS06050	COG0343	queuine tRNA-ribosyltransferase activity
BVH73_RS06055	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BVH73_RS06080	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BVH73_RS06085	COG0463	Glycosyl transferase, family 2
BVH73_RS06085	COG1216	Glycosyl transferase, family 2
BVH73_RS06100	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BVH73_RS06105	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BVH73_RS06110	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BVH73_RS06115	COG0830	nickel cation binding
BVH73_RS06120	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BVH73_RS06125	COG3300	MHYT domain
BVH73_RS06125	COG5001	Diguanylate cyclase
BVH73_RS06130	COG0804	urea catabolic process
BVH73_RS06135	COG0832	Belongs to the urease beta subunit family
BVH73_RS06145	COG0831	urea catabolic process
BVH73_RS06185	COG0789	Transcriptional regulator
BVH73_RS06190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVH73_RS06215	COG0297	glycogen (starch) synthase activity
BVH73_RS06230	COG0672	)-iron permease
BVH73_RS06235	COG2822	iron ion transport
BVH73_RS06245	COG2822	iron ion transport
BVH73_RS06250	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BVH73_RS06260	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BVH73_RS06265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVH73_RS06275	COG0018	arginyl-trna synthetase
BVH73_RS06290	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BVH73_RS06295	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BVH73_RS06300	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BVH73_RS06310	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BVH73_RS06315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BVH73_RS06325	COG0356	it plays a direct role in the translocation of protons across the membrane
BVH73_RS06340	COG0859	PFAM glycosyl transferase family 9
BVH73_RS06435	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BVH73_RS06475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVH73_RS06480	COG0436	Aminotransferase
BVH73_RS06490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVH73_RS06495	COG0384	phenazine biosynthesis protein PhzF
BVH73_RS06510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVH73_RS06515	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVH73_RS06520	COG0583	DNA-binding transcription factor activity
BVH73_RS06525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BVH73_RS06535	COG0735	belongs to the Fur family
BVH73_RS06545	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BVH73_RS06550	COG0321	lipoyl(octanoyl) transferase activity
BVH73_RS06575	COG2755	lipolytic protein G-D-S-L family
BVH73_RS06575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BVH73_RS06580	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVH73_RS06585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVH73_RS06610	COG0606	chelatase, subunit chli
BVH73_RS06620	COG0747	negative chemotaxis
BVH73_RS06625	COG0601	transmembrane transport
BVH73_RS06630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BVH73_RS06635	COG0444	Belongs to the ABC transporter superfamily
BVH73_RS06640	COG4608	Belongs to the ABC transporter superfamily
BVH73_RS06645	COG0347	Belongs to the P(II) protein family
BVH73_RS06650	COG0004	ammonium transporteR
BVH73_RS06680	COG0189	ligase activity
BVH73_RS06690	COG0450	alkyl hydroperoxide reductase
BVH73_RS06695	COG0494	nUDIX hydrolase
BVH73_RS06705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BVH73_RS06730	COG1660	Displays ATPase and GTPase activities
BVH73_RS06735	COG0497	DNA recombination
BVH73_RS06740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BVH73_RS06745	COG1420	regulation of RNA biosynthetic process
BVH73_RS06765	COG1765	OsmC-like protein
BVH73_RS06775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BVH73_RS06795	COG1028	Short-chain dehydrogenase reductase Sdr
BVH73_RS06815	COG0583	DNA-binding transcription factor activity
BVH73_RS06830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVH73_RS06855	COG3237	CsbD-like
BVH73_RS06870	COG2084	Dehydrogenase
BVH73_RS06875	COG3622	Belongs to the hyi family
BVH73_RS06880	COG3960	tartronate-semialdehyde synthase activity
BVH73_RS06885	COG1942	4-Oxalocrotonate Tautomerase
BVH73_RS06890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BVH73_RS06895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVH73_RS06905	COG1136	(ABC) transporter
BVH73_RS06910	COG0012	GTP binding
BVH73_RS06920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BVH73_RS06925	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BVH73_RS06930	COG0255	Belongs to the universal ribosomal protein uL29 family
BVH73_RS06935	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BVH73_RS06940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BVH73_RS06945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BVH73_RS06950	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BVH73_RS06955	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BVH73_RS06960	COG0089	rRNA binding
BVH73_RS06965	COG0088	Forms part of the polypeptide exit tunnel
BVH73_RS06970	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BVH73_RS06975	COG0051	transcription antitermination factor activity, RNA binding
BVH73_RS06980	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BVH73_RS06985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BVH73_RS06990	COG0049	tRNA binding
BVH73_RS06995	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BVH73_RS07030	COG2197	response regulator
BVH73_RS07035	COG1702	phosphate starvation-inducible protein PhoH
BVH73_RS07040	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BVH73_RS07045	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BVH73_RS07055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVH73_RS07060	COG2814	Major facilitator Superfamily
BVH73_RS07065	COG3258	Cytochrome c
BVH73_RS07070	COG2863	cytochrome
BVH73_RS07080	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BVH73_RS07100	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVH73_RS07110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BVH73_RS07110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVH73_RS07120	COG5000	phosphorelay sensor kinase activity
BVH73_RS07125	COG2204	response regulator
BVH73_RS07145	COG3161	chorismate lyase activity
BVH73_RS07150	COG0412	Dienelactone hydrolase
BVH73_RS07155	COG0583	DNA-binding transcription factor activity
BVH73_RS07160	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BVH73_RS07170	COG0725	ABC transporter, periplasmic molybdate-binding protein
BVH73_RS07175	COG4149	molybdate abc transporter
BVH73_RS07180	COG3842	ATPase activity
BVH73_RS07210	COG1970	mechanosensitive ion channel activity
BVH73_RS07240	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BVH73_RS07245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVH73_RS07255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVH73_RS07270	COG1858	cytochrome C peroxidase
BVH73_RS07300	COG2223	nitrite transmembrane transporter activity
BVH73_RS07310	COG0667	Aldo Keto reductase
BVH73_RS07315	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BVH73_RS07325	COG4221	oxidoreductase activity
BVH73_RS07330	COG2329	Antibiotic biosynthesis monooxygenase
BVH73_RS07345	COG4453	Protein conserved in bacteria
BVH73_RS07375	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BVH73_RS07430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVH73_RS07460	COG0784	Response regulator, receiver
BVH73_RS07460	COG2198	Histidine kinase
BVH73_RS07460	COG2205	protein histidine kinase activity
BVH73_RS07465	COG3437	response regulator, receiver
BVH73_RS07475	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BVH73_RS07485	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BVH73_RS07500	COG0587	DNA-directed DNA polymerase activity
BVH73_RS07510	COG3177	Filamentation induced by cAMP protein fic
BVH73_RS07550	COG1484	DNA-dependent DNA replication
BVH73_RS07555	COG4584	PFAM Integrase catalytic
BVH73_RS07565	COG3161	chorismate lyase activity
BVH73_RS07575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVH73_RS07590	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVH73_RS07605	COG3293	Transposase
BVH73_RS07615	COG2217	Heavy metal translocating P-type atpase
BVH73_RS07650	COG4232	protein-disulfide reductase activity
BVH73_RS07680	COG0642	Histidine kinase
BVH73_RS07705	COG0582	viral genome integration into host DNA
BVH73_RS07725	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BVH73_RS07730	COG0085	RNA polymerase activity
BVH73_RS07735	COG0222	ribosome binding
BVH73_RS07740	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BVH73_RS07750	COG0081	regulation of translation
BVH73_RS07755	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BVH73_RS07775	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BVH73_RS07795	COG0134	indole-3-glycerol-phosphate synthase activity
BVH73_RS07800	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BVH73_RS07830	COG0546	phosphoglycolate phosphatase activity
BVH73_RS07835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BVH73_RS07840	COG2967	ApaG domain
BVH73_RS07850	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BVH73_RS07860	COG2354	Protein conserved in bacteria
BVH73_RS07865	COG0730	response to heat
BVH73_RS07880	COG0683	leucine binding
BVH73_RS07885	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BVH73_RS07890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BVH73_RS07900	COG2814	Major facilitator Superfamily
BVH73_RS07915	COG2321	neutral zinc metallopeptidase
BVH73_RS07945	COG2308	Evidence 4 Homologs of previously reported genes of
BVH73_RS07965	COG1305	Transglutaminase-like
BVH73_RS07980	COG0662	Cupin 2, conserved barrel domain protein
BVH73_RS07980	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BVH73_RS07985	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BVH73_RS08000	COG1045	serine acetyltransferase
BVH73_RS08015	COG3206	protein involved in exopolysaccharide biosynthesis
BVH73_RS08015	COG0489	protein tyrosine kinase activity
BVH73_RS08040	COG1215	transferase activity, transferring glycosyl groups
BVH73_RS08060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BVH73_RS08090	COG3220	belongs to the UPF0276 family
BVH73_RS08095	COG2847	Copper chaperone PCu(A)C
BVH73_RS08100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BVH73_RS08105	COG3158	transport of potassium into the cell
BVH73_RS08110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVH73_RS08115	COG2095	MarC family integral membrane protein
BVH73_RS08120	COG0730	response to heat
BVH73_RS08140	COG0357	Ribosomal RNA small subunit methyltransferase G
BVH73_RS08145	COG1192	Involved in chromosome partitioning
BVH73_RS08155	COG1475	DNA binding
BVH73_RS08205	COG1620	l-lactate permease
BVH73_RS08215	COG2271	Major facilitator Superfamily
BVH73_RS08220	COG0640	Transcriptional regulator
BVH73_RS08235	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BVH73_RS08240	COG0706	membrane insertase activity
BVH73_RS08245	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BVH73_RS08255	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BVH73_RS08260	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BVH73_RS08265	COG0592	DNA-directed DNA polymerase activity
BVH73_RS08275	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BVH73_RS08280	COG0732	type I restriction modification DNA specificity domain
BVH73_RS08305	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BVH73_RS08310	COG1335	isochorismatase
BVH73_RS08315	COG1335	isochorismatase
BVH73_RS08325	COG1079	Belongs to the binding-protein-dependent transport system permease family
BVH73_RS08330	COG4603	Belongs to the binding-protein-dependent transport system permease family
BVH73_RS08335	COG3845	ABC transporter
BVH73_RS08355	COG1802	Transcriptional regulator
BVH73_RS08370	COG1116	anion transmembrane transporter activity
BVH73_RS08375	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BVH73_RS08405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVH73_RS08410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVH73_RS08435	COG4191	Histidine kinase
BVH73_RS08440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BVH73_RS08445	COG0604	alcohol dehydrogenase
BVH73_RS08445	COG3321	synthase
BVH73_RS08445	COG1028	Short-chain dehydrogenase reductase Sdr
BVH73_RS08455	COG1802	Transcriptional regulator
BVH73_RS08460	COG0583	DNA-binding transcription factor activity
BVH73_RS08475	COG3383	formate dehydrogenase (NAD+) activity
BVH73_RS08480	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BVH73_RS08490	COG0166	Belongs to the GPI family
BVH73_RS08500	COG0837	glucose binding
BVH73_RS08505	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BVH73_RS08515	COG0800	Aldolase
BVH73_RS08520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVH73_RS08530	COG1653	transport
BVH73_RS08535	COG1175	transmembrane transport
BVH73_RS08540	COG0395	ABC-type sugar transport system, permease component
BVH73_RS08545	COG3842	ATPase activity
BVH73_RS08570	COG1294	oxidase, subunit
BVH73_RS08575	COG1271	oxidase subunit
BVH73_RS08585	COG1230	cation diffusion facilitator family transporter
BVH73_RS08615	COG0752	glycyl-tRNA synthetase alpha subunit
BVH73_RS08620	COG0751	glycine-tRNA ligase activity
BVH73_RS08625	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BVH73_RS08645	COG0346	lactoylglutathione lyase activity
BVH73_RS08665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BVH73_RS08675	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BVH73_RS08680	COG0735	belongs to the Fur family
BVH73_RS08685	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVH73_RS08690	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BVH73_RS08715	COG5001	Diguanylate cyclase
BVH73_RS08715	COG2203	Gaf domain
BVH73_RS08715	COG4251	negative regulation of phosphorylation
BVH73_RS08715	COG3706	GGDEF domain
BVH73_RS08735	COG0477	Major facilitator Superfamily
BVH73_RS08740	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BVH73_RS08750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVH73_RS08770	COG2204	response regulator
BVH73_RS08780	COG2205	protein histidine kinase activity
BVH73_RS08785	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BVH73_RS08790	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BVH73_RS08810	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BVH73_RS08815	COG4988	ABC transporter
BVH73_RS08845	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BVH73_RS08850	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BVH73_RS08855	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BVH73_RS08860	COG2205	protein histidine kinase activity
BVH73_RS08865	COG0745	RESPONSE REGULATOR receiver
BVH73_RS08870	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BVH73_RS08895	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
BVH73_RS08905	COG2814	Major facilitator Superfamily
BVH73_RS08920	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BVH73_RS08925	COG0739	heme binding
BVH73_RS08930	COG0739	heme binding
BVH73_RS08935	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BVH73_RS08940	COG0316	Belongs to the HesB IscA family
BVH73_RS08945	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BVH73_RS08950	COG1862	Preprotein translocase
BVH73_RS08955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVH73_RS08960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVH73_RS08970	COG2922	Belongs to the Smg family
BVH73_RS08975	COG0758	DNA mediated transformation
BVH73_RS08980	COG1652	LysM domain
BVH73_RS08985	COG0242	peptide deformylase activity
BVH73_RS08995	COG0501	Belongs to the peptidase M48B family
BVH73_RS09000	COG1950	PFAM Membrane protein of
BVH73_RS09010	COG0625	glutathione transferase activity
BVH73_RS09020	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BVH73_RS09025	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BVH73_RS09030	COG0280	phosphate acetyltransferase
BVH73_RS09030	COG0281	malic enzyme
BVH73_RS09045	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BVH73_RS09050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVH73_RS09055	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BVH73_RS09065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BVH73_RS09070	COG0006	proline dipeptidase activity
BVH73_RS09085	COG4106	trans-aconitate 2-methyltransferase activity
BVH73_RS09100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVH73_RS09110	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BVH73_RS09120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BVH73_RS09140	COG1850	ribulose-bisphosphate carboxylase activity
BVH73_RS09170	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BVH73_RS09175	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BVH73_RS09180	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BVH73_RS09185	COG2193	ferroxidase activity
BVH73_RS09195	COG1192	Involved in chromosome partitioning
BVH73_RS09215	COG1484	DNA-dependent DNA replication
BVH73_RS09220	COG4584	PFAM Integrase catalytic
BVH73_RS09230	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BVH73_RS09245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BVH73_RS09250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BVH73_RS09255	COG0583	DNA-binding transcription factor activity
BVH73_RS09260	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BVH73_RS09265	COG3954	Phosphoribulokinase
BVH73_RS09270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BVH73_RS09275	COG0546	phosphoglycolate phosphatase activity
BVH73_RS09280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BVH73_RS09285	COG0126	phosphoglycerate kinase activity
BVH73_RS09300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BVH73_RS09310	COG1466	dna polymerase III delta subunit
BVH73_RS09320	COG0495	leucyl-tRNA aminoacylation
BVH73_RS09325	COG1252	NADH dehydrogenase
BVH73_RS09375	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BVH73_RS09380	COG1280	lysine exporter protein (LysE YggA)
BVH73_RS09385	COG0154	amidase activity
BVH73_RS09390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BVH73_RS09395	COG1077	Cell shape determining protein MreB Mrl
BVH73_RS09400	COG1792	Involved in formation and maintenance of cell shape
BVH73_RS09410	COG0768	penicillin binding
BVH73_RS09415	COG0772	Belongs to the SEDS family
BVH73_RS09465	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BVH73_RS09470	COG0010	Belongs to the arginase family
BVH73_RS09475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVH73_RS09500	COG0410	ABC transporter
BVH73_RS09510	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BVH73_RS09515	COG0174	glutamine synthetase
BVH73_RS09530	COG3842	ATPase activity
BVH73_RS09535	COG1176	ABC-type spermidine putrescine transport system, permease component I
BVH73_RS09540	COG1177	transmembrane transport
BVH73_RS09550	COG1012	belongs to the aldehyde dehydrogenase family
BVH73_RS09555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVH73_RS09560	COG0300	oxidoreductase activity
BVH73_RS09580	COG2197	response regulator
BVH73_RS09595	COG2813	Specifically methylates the guanine in position
BVH73_RS09595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVH73_RS09600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVH73_RS09615	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BVH73_RS09625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BVH73_RS09630	COG3647	Membrane
BVH73_RS09645	COG1278	Cold shock
BVH73_RS09660	COG2255	four-way junction helicase activity
BVH73_RS09680	COG0406	alpha-ribazole phosphatase activity
BVH73_RS09690	COG2814	Major facilitator Superfamily
BVH73_RS09725	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BVH73_RS09730	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BVH73_RS09740	COG1294	oxidase, subunit
BVH73_RS09745	COG1271	oxidase subunit
BVH73_RS09760	COG3842	ATPase activity
BVH73_RS09770	COG1175	transmembrane transport
BVH73_RS09795	COG3842	ATPase activity
BVH73_RS09800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BVH73_RS09805	COG1846	Transcriptional regulator
BVH73_RS09810	COG3038	cytochrome b561
BVH73_RS09820	COG2353	YceI-like domain
BVH73_RS09830	COG0402	S-adenosylhomocysteine deaminase activity
BVH73_RS09835	COG1960	acyl-CoA dehydrogenase activity
BVH73_RS09840	COG0829	nickel cation binding
BVH73_RS09850	COG0443	Heat shock 70 kDa protein
BVH73_RS09860	COG1960	acyl-CoA dehydrogenase activity
BVH73_RS09870	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BVH73_RS09880	COG1960	acyl-CoA dehydrogenase activity
BVH73_RS09890	COG0318	PFAM AMP-dependent synthetase and ligase
BVH73_RS09895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVH73_RS09910	COG1024	Enoyl-CoA hydratase
BVH73_RS09930	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVH73_RS09940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BVH73_RS09955	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVH73_RS09960	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BVH73_RS09965	COG0138	bifunctional purine biosynthesis protein purh
BVH73_RS09970	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BVH73_RS09985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVH73_RS10000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVH73_RS10010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVH73_RS10020	COG0632	four-way junction helicase activity
BVH73_RS10025	COG3511	phospholipase C
BVH73_RS10035	COG1028	Short-chain dehydrogenase reductase Sdr
BVH73_RS10040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BVH73_RS10040	COG2169	Transcriptional regulator
BVH73_RS10055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BVH73_RS10060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVH73_RS10065	COG2982	Protein involved in outer membrane biogenesis
BVH73_RS10075	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BVH73_RS10080	COG1704	LemA family
BVH73_RS10090	COG2326	polyphosphate kinase activity
BVH73_RS10105	COG0312	modulator of DNA gyrase
BVH73_RS10115	COG0315	cyclic pyranopterin monophosphate synthase activity
BVH73_RS10145	COG0315	cyclic pyranopterin monophosphate synthase activity
BVH73_RS10150	COG0284	orotidine-5'-phosphate decarboxylase activity
BVH73_RS10160	COG4095	Psort location CytoplasmicMembrane, score
BVH73_RS10165	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BVH73_RS10175	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BVH73_RS10185	COG0668	transmembrane transport
BVH73_RS10195	COG0642	Histidine kinase
BVH73_RS10205	COG1881	PFAM PEBP family protein
BVH73_RS10210	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BVH73_RS10220	COG1116	anion transmembrane transporter activity
BVH73_RS10230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BVH73_RS10240	COG2885	chlorophyll binding
BVH73_RS10245	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BVH73_RS10250	COG0247	lactate metabolic process
BVH73_RS10285	COG2326	polyphosphate kinase activity
BVH73_RS10295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BVH73_RS10300	COG2890	protein-(glutamine-N5) methyltransferase activity
BVH73_RS10305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BVH73_RS10310	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BVH73_RS10320	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BVH73_RS10325	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BVH73_RS10330	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BVH73_RS10335	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BVH73_RS10340	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BVH73_RS10345	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BVH73_RS10350	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BVH73_RS10355	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BVH73_RS10360	COG1841	ribosomal large subunit assembly
BVH73_RS10365	COG0200	Binds to the 23S rRNA
BVH73_RS10370	COG0201	protein transport
BVH73_RS10380	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BVH73_RS10385	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BVH73_RS10390	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BVH73_RS10395	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BVH73_RS10400	COG0202	RNA polymerase activity
BVH73_RS10405	COG0203	ribosomal protein L17
BVH73_RS10410	COG1131	(ABC) transporter
BVH73_RS10415	COG0842	Transport permease protein
BVH73_RS10420	COG4232	protein-disulfide reductase activity
BVH73_RS10430	COG0243	molybdopterin cofactor binding
BVH73_RS10435	COG1309	transcriptional regulator
BVH73_RS10440	COG1028	Short-chain dehydrogenase reductase Sdr
BVH73_RS10455	COG1960	acyl-CoA dehydrogenase activity
BVH73_RS10460	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVH73_RS10460	COG1024	Enoyl-CoA hydratase
BVH73_RS10470	COG0183	Belongs to the thiolase family
BVH73_RS10475	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BVH73_RS10485	COG1040	competence protein
BVH73_RS10490	COG2226	methyltransferase
BVH73_RS10505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BVH73_RS10535	COG1612	heme a metabolic process
BVH73_RS10540	COG0109	protoheme IX farnesyltransferase activity
BVH73_RS10545	COG1999	signal sequence binding
BVH73_RS10550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVH73_RS10555	COG0436	Aminotransferase
BVH73_RS10560	COG0583	DNA-binding transcription factor activity
BVH73_RS10570	COG0795	lipopolysaccharide-transporting ATPase activity
BVH73_RS10575	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BVH73_RS10605	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BVH73_RS10610	COG0509	glycine decarboxylation via glycine cleavage system
BVH73_RS10615	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BVH73_RS10615	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BVH73_RS10625	COG1760	l-serine dehydratase
BVH73_RS10660	COG2951	lytic endotransglycosylase activity
BVH73_RS10680	COG1530	ribonuclease E activity
BVH73_RS10685	COG0424	maF-like protein
BVH73_RS10690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVH73_RS10695	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BVH73_RS10715	COG0540	Belongs to the ATCase OTCase family
BVH73_RS10720	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BVH73_RS10730	COG1678	Uncharacterized ACR, COG1678
BVH73_RS10735	COG0415	Belongs to the DNA photolyase family
BVH73_RS10740	COG0784	Response regulator, receiver
BVH73_RS10740	COG2198	Histidine kinase
BVH73_RS10740	COG0643	Histidine kinase
BVH73_RS10745	COG0840	transmembrane signaling receptor activity
BVH73_RS10765	COG1773	rubredoxin
BVH73_RS10775	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BVH73_RS10780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVH73_RS10785	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BVH73_RS10800	COG1028	Short-chain dehydrogenase reductase Sdr
BVH73_RS10805	COG3150	esterase
BVH73_RS10815	COG2267	carboxylic ester hydrolase activity
BVH73_RS10835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVH73_RS10835	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BVH73_RS10840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BVH73_RS10845	COG0741	lytic transglycosylase activity
BVH73_RS10850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVH73_RS10860	COG0210	DNA helicase
BVH73_RS10865	COG0318	PFAM AMP-dependent synthetase and ligase
BVH73_RS10875	COG0617	tRNA 3'-terminal CCA addition
BVH73_RS10880	COG1331	Highly conserved protein containing a thioredoxin domain
BVH73_RS10890	COG0473	3-isopropylmalate dehydrogenase activity
BVH73_RS10915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVH73_RS10930	COG1469	GTP cyclohydrolase I activity
BVH73_RS10945	COG0038	chloride channel
BVH73_RS10950	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BVH73_RS10960	COG4575	ribosome binding
BVH73_RS10975	COG3668	Plasmid stabilization system
BVH73_RS10995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BVH73_RS11000	COG2391	methyltransferase activity
BVH73_RS11005	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BVH73_RS11015	COG2885	chlorophyll binding
BVH73_RS11020	COG0823	Involved in the tonB-independent uptake of proteins
BVH73_RS11065	COG0662	Cupin 2, conserved barrel domain protein
BVH73_RS11065	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BVH73_RS11080	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVH73_RS11085	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BVH73_RS11115	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BVH73_RS11155	COG0824	Thioesterase
BVH73_RS11170	COG0436	Aminotransferase
BVH73_RS11175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVH73_RS11180	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BVH73_RS11195	COG0121	glutamine amidotransferase
BVH73_RS11205	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVH73_RS11205	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVH73_RS11210	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BVH73_RS11215	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BVH73_RS11220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVH73_RS11220	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BVH73_RS11230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BVH73_RS11235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BVH73_RS11240	COG0492	ferredoxin-NADP+ reductase activity
BVH73_RS11250	COG1674	ftsk spoiiie
BVH73_RS11255	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BVH73_RS11260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BVH73_RS11285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BVH73_RS11285	COG0543	2 iron, 2 sulfur cluster binding
BVH73_RS11290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVH73_RS11295	COG1530	ribonuclease E activity
BVH73_RS11300	COG0564	pseudouridine synthase activity
BVH73_RS11310	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BVH73_RS11310	COG0616	signal peptide processing
BVH73_RS11315	COG0424	maF-like protein
BVH73_RS11320	COG2391	methyltransferase activity
BVH73_RS11330	COG1399	metal-binding, possibly nucleic acid-binding protein
BVH73_RS11335	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BVH73_RS11340	COG0416	fatty acid biosynthetic process
BVH73_RS11345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVH73_RS11350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BVH73_RS11355	COG1028	Short-chain dehydrogenase reductase Sdr
BVH73_RS11360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVH73_RS11365	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVH73_RS11390	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVH73_RS11395	COG0481	GTPase activity
BVH73_RS11410	COG0571	ribonuclease III activity
BVH73_RS11415	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BVH73_RS11420	COG1381	Involved in DNA repair and RecF pathway recombination
BVH73_RS11430	COG0736	holo-[acyl-carrier-protein] synthase activity
BVH73_RS11435	COG1472	Belongs to the glycosyl hydrolase 3 family
BVH73_RS11450	COG2264	protein methyltransferase activity
BVH73_RS11460	COG0511	ligase activity, forming carbon-carbon bonds
BVH73_RS11465	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BVH73_RS11480	COG0488	(ABC) transporter
BVH73_RS11500	COG0351	phosphomethylpyrimidine kinase
BVH73_RS11505	COG0352	thiamine-phosphate diphosphorylase activity
BVH73_RS11510	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BVH73_RS11520	COG0799	negative regulation of ribosome biogenesis
BVH73_RS11525	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BVH73_RS11530	COG0408	coproporphyrinogen oxidase activity
BVH73_RS11545	COG2084	Dehydrogenase
BVH73_RS11555	COG3634	alkyl hydroperoxide reductase activity
BVH73_RS11560	COG3022	response to hydroperoxide
BVH73_RS11565	COG1393	Belongs to the ArsC family
BVH73_RS11575	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BVH73_RS11600	COG0039	L-malate dehydrogenase activity
BVH73_RS11605	COG2188	Transcriptional regulator
BVH73_RS11615	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BVH73_RS11620	COG1053	succinate dehydrogenase
BVH73_RS11625	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BVH73_RS11630	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BVH73_RS11635	COG0372	Belongs to the citrate synthase family
BVH73_RS11645	COG2226	methyltransferase
BVH73_RS11650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BVH73_RS11660	COG0066	3-isopropylmalate dehydratase activity
BVH73_RS11665	COG0473	3-isopropylmalate dehydrogenase activity
BVH73_RS11670	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BVH73_RS11680	COG0101	tRNA pseudouridine synthase activity
BVH73_RS11685	COG0135	phosphoribosylanthranilate isomerase activity
BVH73_RS11690	COG0133	tryptophan synthase activity
BVH73_RS11695	COG0159	tryptophan synthase activity
BVH73_RS11700	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BVH73_RS11705	COG0285	dihydrofolate synthase activity
BVH73_RS11715	COG1286	toxin biosynthetic process
BVH73_RS11730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVH73_RS11740	COG0167	dihydroorotate dehydrogenase activity
BVH73_RS11745	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BVH73_RS11755	COG0339	signal peptide processing
BVH73_RS11760	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BVH73_RS11765	COG4566	intracellular signal transduction
BVH73_RS11775	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BVH73_RS11780	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVH73_RS11785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVH73_RS11790	COG0791	NLP P60 protein
BVH73_RS11795	COG0604	alcohol dehydrogenase
BVH73_RS11820	COG4654	Cytochrome c, class I
BVH73_RS11855	COG1414	Transcriptional regulator
BVH73_RS11865	COG1139	Iron-sulfur cluster binding protein
BVH73_RS11870	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BVH73_RS11875	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BVH73_RS11885	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BVH73_RS11890	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BVH73_RS11895	COG0148	phosphopyruvate hydratase activity
BVH73_RS11905	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BVH73_RS11910	COG0504	CTP synthase activity
BVH73_RS11925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BVH73_RS11930	COG2081	HI0933 family
BVH73_RS11935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BVH73_RS11950	COG1185	polyribonucleotide nucleotidyltransferase activity
BVH73_RS11955	COG1063	alcohol dehydrogenase
BVH73_RS11960	COG0149	triose-phosphate isomerase activity
BVH73_RS11965	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BVH73_RS11975	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVH73_RS11980	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVH73_RS11985	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVH73_RS11990	COG0649	NAD binding
BVH73_RS12005	COG1034	ATP synthesis coupled electron transport
BVH73_RS12010	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BVH73_RS12025	COG0713	ATP synthesis coupled electron transport
BVH73_RS12040	COG1007	ATP synthesis coupled electron transport
BVH73_RS12055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVH73_RS12070	COG2373	Large extracellular alpha-helical protein
BVH73_RS12075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVH73_RS12080	COG2223	nitrite transmembrane transporter activity
BVH73_RS12105	COG0475	glutathione-regulated potassium exporter activity
BVH73_RS12110	COG1028	Short-chain dehydrogenase reductase Sdr
BVH73_RS12125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVH73_RS12170	COG0700	Nucleoside recognition
BVH73_RS12180	COG2233	PERMEase
BVH73_RS12190	COG1953	Uracil, thiamine, allantoin
BVH73_RS12195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVH73_RS12210	COG2186	Transcriptional regulator
BVH73_RS12225	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BVH73_RS12230	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BVH73_RS12235	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BVH73_RS12250	COG0523	cobalamin synthesis protein
BVH73_RS12260	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BVH73_RS12270	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BVH73_RS12275	COG1560	Kdo2-lipid A biosynthetic process
BVH73_RS12285	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BVH73_RS12295	COG3123	guanosine phosphorylase activity
BVH73_RS12300	COG0137	argininosuccinate synthase activity
BVH73_RS12325	COG1793	dna ligase
BVH73_RS12330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BVH73_RS12335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BVH73_RS12340	COG2814	Major facilitator Superfamily
BVH73_RS12345	COG0489	protein tyrosine kinase activity
BVH73_RS12355	COG0151	Belongs to the GarS family
BVH73_RS12360	COG0217	transcriptional regulatory protein
BVH73_RS12365	COG0433	COG0433 Predicted ATPase
BVH73_RS12375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVH73_RS12395	COG2223	nitrite transmembrane transporter activity
BVH73_RS12400	COG1272	protein, Hemolysin III
BVH73_RS12420	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BVH73_RS12450	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BVH73_RS12460	COG0004	ammonium transporteR
BVH73_RS12465	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BVH73_RS12470	COG2867	negative regulation of translational initiation
BVH73_RS12500	COG0683	leucine binding
BVH73_RS12510	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BVH73_RS12520	COG3706	GGDEF domain
BVH73_RS12555	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BVH73_RS12570	COG2233	PERMEase
BVH73_RS12595	COG0303	'Molybdopterin
BVH73_RS12600	COG0746	molybdenum cofactor guanylyltransferase activity
BVH73_RS12615	COG0728	peptidoglycan biosynthetic process
BVH73_RS12620	COG0268	Binds directly to 16S ribosomal RNA
BVH73_RS12630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVH73_RS12635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BVH73_RS12650	COG1162	GTPase activity
BVH73_RS12655	COG2154	pterin-4-alpha-carbinolamine dehydratase
BVH73_RS12660	COG0501	Belongs to the peptidase M48B family
BVH73_RS12665	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BVH73_RS12680	COG2226	methyltransferase
BVH73_RS12685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVH73_RS12690	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BVH73_RS12700	COG0859	PFAM glycosyl transferase family 9
BVH73_RS12710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BVH73_RS12715	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BVH73_RS12720	COG1914	H( )-stimulated, divalent metal cation uptake system
BVH73_RS12725	COG1968	undecaprenyl-diphosphatase activity
BVH73_RS12730	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BVH73_RS12750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BVH73_RS12775	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BVH73_RS12790	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BVH73_RS12795	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BVH73_RS12810	COG0004	ammonium transporteR
BVH73_RS12830	COG3328	transposase activity
BVH73_RS12835	COG0859	PFAM glycosyl transferase family 9
BVH73_RS12845	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVH73_RS12845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVH73_RS12850	COG1289	transmembrane transporter activity
BVH73_RS12855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BVH73_RS12865	COG0483	inositol monophosphate 1-phosphatase activity
BVH73_RS12870	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BVH73_RS12875	COG1045	serine acetyltransferase
BVH73_RS12880	COG0840	transmembrane signaling receptor activity
BVH73_RS12900	COG0492	ferredoxin-NADP+ reductase activity
BVH73_RS12905	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BVH73_RS12920	COG0640	Transcriptional regulator
BVH73_RS12930	COG2183	response to ionizing radiation
BVH73_RS12935	COG0542	response to heat
BVH73_RS12945	COG1999	signal sequence binding
BVH73_RS12955	COG1999	signal sequence binding
BVH73_RS12960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BVH73_RS12975	COG0583	DNA-binding transcription factor activity
BVH73_RS12985	COG1104	cysteine desulfurase activity
BVH73_RS12990	COG0822	iron-sulfur transferase activity
BVH73_RS13000	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BVH73_RS13010	COG0633	Ferredoxin
BVH73_RS13015	COG2176	DNA-directed DNA polymerase activity
BVH73_RS13025	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BVH73_RS13030	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BVH73_RS13030	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BVH73_RS13035	COG1643	Atp-dependent helicase
BVH73_RS13050	COG3278	Belongs to the heme-copper respiratory oxidase family
BVH73_RS13080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVH73_RS13095	COG1522	sequence-specific DNA binding
BVH73_RS13100	COG3483	tryptophan 2,3-dioxygenase activity
BVH73_RS13110	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BVH73_RS13120	COG3186	Phenylalanine-4-hydroxylase
BVH73_RS13125	COG0625	glutathione transferase activity
BVH73_RS13175	COG0084	hydrolase, TatD family'
BVH73_RS13180	COG0326	Molecular chaperone. Has ATPase activity
BVH73_RS13185	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BVH73_RS13195	COG0335	large ribosomal subunit rRNA binding
BVH73_RS13200	COG0336	Belongs to the RNA methyltransferase TrmD family
BVH73_RS13205	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BVH73_RS13225	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BVH73_RS13230	COG0617	tRNA 3'-terminal CCA addition
BVH73_RS13240	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BVH73_RS13245	COG0628	permease
BVH73_RS13250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BVH73_RS13255	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BVH73_RS13265	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BVH73_RS13270	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BVH73_RS13275	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVH73_RS13280	COG0477	Major facilitator Superfamily
BVH73_RS13285	COG0516	GMP reductase activity
BVH73_RS13290	COG0210	DNA helicase
BVH73_RS13305	COG0840	transmembrane signaling receptor activity
BVH73_RS13315	COG1063	alcohol dehydrogenase
BVH73_RS13325	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BVH73_RS13330	COG0308	aminopeptidase N
BVH73_RS13340	COG0484	heat shock protein binding
BVH73_RS13345	COG0443	Heat shock 70 kDa protein
BVH73_RS13350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BVH73_RS13360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVH73_RS13370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BVH73_RS13370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVH73_RS13385	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BVH73_RS13390	COG1187	pseudouridine synthase activity
BVH73_RS13400	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BVH73_RS13420	COG0124	histidyl-tRNA synthetase
BVH73_RS13425	COG2976	Protein conserved in bacteria
BVH73_RS13430	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVH73_RS13435	COG1160	GTP binding
BVH73_RS13440	COG1923	regulation of RNA biosynthetic process
BVH73_RS13445	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BVH73_RS13450	COG0330	HflC and HflK could
BVH73_RS13455	COG0330	HflC and HflK could
BVH73_RS13460	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BVH73_RS13465	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BVH73_RS13470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BVH73_RS13490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVH73_RS13490	COG0519	Catalyzes the synthesis of GMP from XMP
BVH73_RS13505	COG1619	proteins homologs of microcin C7 resistance protein MccF
BVH73_RS13520	COG0436	Aminotransferase
BVH73_RS13525	COG2171	N-acyltransferase activity
BVH73_RS13535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVH73_RS13540	COG2890	protein-(glutamine-N5) methyltransferase activity
BVH73_RS13545	COG0488	(ABC) transporter
BVH73_RS13555	COG0534	Mate efflux family protein
BVH73_RS13565	COG0254	rRNA binding
BVH73_RS13570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BVH73_RS13590	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVH73_RS13590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BVH73_RS13600	COG1215	transferase activity, transferring glycosyl groups
BVH73_RS13605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BVH73_RS13610	COG2076	Multidrug Resistance protein
BVH73_RS13620	COG1960	acyl-CoA dehydrogenase activity
BVH73_RS13630	COG0505	Belongs to the CarA family
BVH73_RS13640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BVH73_RS13645	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVH73_RS13655	COG1534	Rna-binding protein
BVH73_RS13665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVH73_RS13675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVH73_RS13695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BVH73_RS13700	COG0573	inorganic phosphate transmembrane transporter activity
BVH73_RS13705	COG0581	inorganic phosphate transmembrane transporter activity
BVH73_RS13720	COG0745	RESPONSE REGULATOR receiver
BVH73_RS13730	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BVH73_RS13735	COG0248	Ppx GppA phosphatase
BVH73_RS13740	COG0406	alpha-ribazole phosphatase activity
BVH73_RS13745	COG0537	adenosine 5'-monophosphoramidase activity
BVH73_RS13750	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVH73_RS13755	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BVH73_RS13760	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BVH73_RS13765	COG1993	acr, cog1993
BVH73_RS13770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BVH73_RS13775	COG0651	ATP synthesis coupled electron transport
BVH73_RS13780	COG3260	NADH ubiquinone oxidoreductase 20
BVH73_RS13785	COG0649	NAD binding
BVH73_RS13790	COG0651	ATP synthesis coupled electron transport
BVH73_RS13800	COG0650	Formate hydrogenlyase subunit 4
BVH73_RS13805	COG0114	fumarate hydratase activity
BVH73_RS13820	COG0156	8-amino-7-oxononanoate synthase activity
BVH73_RS13850	COG1253	flavin adenine dinucleotide binding
BVH73_RS13855	COG0626	cystathionine gamma-synthase activity
BVH73_RS13870	COG0560	Phosphoserine phosphatase
BVH73_RS13875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BVH73_RS13880	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BVH73_RS13880	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BVH73_RS13905	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVH73_RS13910	COG1570	exodeoxyribonuclease VII activity
BVH73_RS13915	COG0811	peptide transport
BVH73_RS13925	COG1663	tetraacyldisaccharide 4'-kinase activity
BVH73_RS13930	COG2835	tetraacyldisaccharide 4'-kinase activity
BVH73_RS13935	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BVH73_RS13940	COG0563	adenylate kinase activity
BVH73_RS13965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BVH73_RS13975	COG0367	asparagine synthase
BVH73_RS13980	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BVH73_RS13985	COG1028	Short-chain dehydrogenase reductase Sdr
BVH73_RS13995	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVH73_RS14010	COG0544	peptidyl-prolyl cis-trans isomerase activity
BVH73_RS14015	COG0740	serine-type endopeptidase activity
BVH73_RS14020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BVH73_RS14025	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BVH73_RS14055	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BVH73_RS14090	COG1309	transcriptional regulator
BVH73_RS14105	COG2226	methyltransferase
BVH73_RS14130	COG2003	Belongs to the UPF0758 family
BVH73_RS14140	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BVH73_RS14145	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BVH73_RS14185	COG0583	DNA-binding transcription factor activity
BVH73_RS14190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVH73_RS14195	COG0477	Major facilitator Superfamily
BVH73_RS14205	COG2963	transposase activity
BVH73_RS14210	COG0582	viral genome integration into host DNA
BVH73_RS14215	COG3012	SEC-C Motif Domain Protein
BVH73_RS14250	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVH73_RS14250	COG1024	Enoyl-CoA hydratase
BVH73_RS14260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVH73_RS14285	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BVH73_RS14295	COG0667	Aldo Keto reductase
BVH73_RS14305	COG0655	NAD(P)H dehydrogenase (quinone) activity
BVH73_RS14310	COG0583	DNA-binding transcription factor activity
BVH73_RS14320	COG0431	NADPH-dependent FMN reductase
BVH73_RS14325	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BVH73_RS14340	COG2022	thiamine diphosphate biosynthetic process
BVH73_RS14370	COG0318	PFAM AMP-dependent synthetase and ligase
BVH73_RS14395	COG4166	transmembrane transport
BVH73_RS14400	COG4174	ABC transporter (Permease)
BVH73_RS14405	COG4239	(ABC) transporter, permease
BVH73_RS14410	COG4172	Belongs to the ABC transporter superfamily
BVH73_RS14415	COG0779	Required for maturation of 30S ribosomal subunits
BVH73_RS14420	COG0195	Participates in both transcription termination and antitermination
BVH73_RS14420	COG2251	uridine kinase activity
BVH73_RS14425	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BVH73_RS14430	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BVH73_RS14435	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BVH73_RS14460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BVH73_RS14470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVH73_RS14475	COG1902	pentaerythritol trinitrate reductase activity
BVH73_RS14480	COG0243	molybdopterin cofactor binding
BVH73_RS14485	COG0437	4 iron, 4 sulfur cluster binding
BVH73_RS14490	COG3302	dmso reductase anchor subunit
BVH73_RS14510	COG1199	ATP-dependent helicase activity
BVH73_RS14520	COG0564	pseudouridine synthase activity
BVH73_RS14530	COG3243	poly(R)-hydroxyalkanoic acid synthase
BVH73_RS14535	COG0183	Belongs to the thiolase family
BVH73_RS14540	COG1028	Short-chain dehydrogenase reductase Sdr
BVH73_RS14550	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVH73_RS14560	COG0730	response to heat
BVH73_RS14565	COG1584	GPR1 FUN34 yaaH family protein
BVH73_RS14580	COG0708	Exodeoxyribonuclease III
BVH73_RS14595	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BVH73_RS14605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BVH73_RS14610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BVH73_RS14615	COG0196	riboflavin kinase activity
BVH73_RS14620	COG1278	Cold shock
BVH73_RS14625	COG0586	Pfam SNARE associated Golgi protein
BVH73_RS14630	COG0180	Tryptophanyl-tRNA synthetase
BVH73_RS14635	COG1994	Peptidase M50
BVH73_RS14640	COG0009	L-threonylcarbamoyladenylate synthase
BVH73_RS14645	COG0613	PHP domain protein
BVH73_RS14655	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BVH73_RS14660	COG1666	GTP binding
BVH73_RS14665	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BVH73_RS14675	COG0242	peptide deformylase activity
BVH73_RS14690	COG0567	Dehydrogenase, E1 component
BVH73_RS14695	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVH73_RS14700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVH73_RS14705	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BVH73_RS14715	COG0668	transmembrane transport
BVH73_RS14720	COG0318	PFAM AMP-dependent synthetase and ligase
BVH73_RS14725	COG2119	membrane
BVH73_RS14740	COG1960	acyl-CoA dehydrogenase activity
BVH73_RS14760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BVH73_RS14765	COG0243	molybdopterin cofactor binding
BVH73_RS14770	COG2146	nitrite reductase [NAD(P)H] activity
BVH73_RS14775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVH73_RS14780	COG1116	anion transmembrane transporter activity
BVH73_RS14785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVH73_RS14790	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVH73_RS14795	COG3707	response regulator
BVH73_RS14805	COG1295	ribonuclease BN
BVH73_RS14820	COG0277	FAD linked oxidase domain protein
BVH73_RS14825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVH73_RS14830	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVH73_RS14835	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BVH73_RS14835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BVH73_RS14840	COG2059	Chromate
BVH73_RS14850	COG2224	Isocitrate lyase
BVH73_RS14860	COG0477	Major facilitator Superfamily
BVH73_RS14870	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BVH73_RS14875	COG0133	tryptophan synthase activity
BVH73_RS14885	COG1132	(ABC) transporter
BVH73_RS14895	COG0739	heme binding
BVH73_RS14900	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BVH73_RS14910	COG5001	Diguanylate cyclase
BVH73_RS14915	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BVH73_RS14920	COG0542	response to heat
BVH73_RS14940	COG0583	DNA-binding transcription factor activity
BVH73_RS14945	COG0129	dihydroxy-acid dehydratase activity
BVH73_RS14955	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BVH73_RS14965	COG0583	DNA-binding transcription factor activity
BVH73_RS14970	COG2252	PERMEase
BVH73_RS14975	COG0402	S-adenosylhomocysteine deaminase activity
BVH73_RS14980	COG3845	ABC transporter
BVH73_RS14985	COG4603	Belongs to the binding-protein-dependent transport system permease family
BVH73_RS14990	COG1079	Belongs to the binding-protein-dependent transport system permease family
BVH73_RS15000	COG1741	Belongs to the pirin family
BVH73_RS15005	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BVH73_RS15015	COG0412	Dienelactone hydrolase
BVH73_RS15045	COG1722	exodeoxyribonuclease VII activity
BVH73_RS15050	COG0142	geranyltranstransferase activity
BVH73_RS15055	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BVH73_RS15060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BVH73_RS15070	COG1121	(ABC) transporter
BVH73_RS15075	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVH73_RS15080	COG1469	GTP cyclohydrolase I activity
BVH73_RS15085	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BVH73_RS15095	COG1280	lysine exporter protein (LysE YggA)
BVH73_RS15100	COG5001	Diguanylate cyclase
BVH73_RS15105	COG2890	protein-(glutamine-N5) methyltransferase activity
BVH73_RS15110	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BVH73_RS15130	COG0174	glutamine synthetase
BVH73_RS15140	COG3852	Histidine kinase
BVH73_RS15145	COG2204	response regulator
BVH73_RS15155	COG0803	Belongs to the bacterial solute-binding protein 9 family
BVH73_RS15160	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BVH73_RS15165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVH73_RS15170	COG0129	dihydroxy-acid dehydratase activity
BVH73_RS15175	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BVH73_RS15195	COG4206	TonB-dependent receptor
BVH73_RS15210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVH73_RS15215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVH73_RS15220	COG0271	Belongs to the BolA IbaG family
BVH73_RS15225	COG2917	probably involved in intracellular septation
BVH73_RS15240	COG0024	Methionine aminopeptidase
BVH73_RS15245	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BVH73_RS15245	COG0047	phosphoribosylformylglycinamidine synthase activity
BVH73_RS15265	COG1959	2 iron, 2 sulfur cluster binding
BVH73_RS15285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVH73_RS15295	COG0251	oxidation-reduction process
BVH73_RS15300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BVH73_RS15310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BVH73_RS15315	COG0657	acetylesterase activity
BVH73_RS15325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BVH73_RS15330	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BVH73_RS15345	COG0084	hydrolase, TatD family'
BVH73_RS15415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVH73_RS15450	COG3704	protein secretion by the type IV secretion system
BVH73_RS15530	COG1192	Involved in chromosome partitioning
BVH73_RS15575	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress