locus-tag	class	description
AKN93_RS00010	COG1132	(ABC) transporter
AKN93_RS00015	COG3284	Transcriptional regulator
AKN93_RS00050	COG0435	Glutathione S-transferase
AKN93_RS00060	COG1522	sequence-specific DNA binding
AKN93_RS00070	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AKN93_RS00080	COG1294	oxidase, subunit
AKN93_RS00090	COG3162	membrane
AKN93_RS00095	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AKN93_RS00100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AKN93_RS00105	COG1570	exodeoxyribonuclease VII activity
AKN93_RS00110	COG4942	peptidase
AKN93_RS00115	COG0668	transmembrane transport
AKN93_RS00130	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AKN93_RS00135	COG2900	Belongs to the SlyX family
AKN93_RS00150	COG0442	prolyl-tRNA aminoacylation
AKN93_RS00155	COG0786	glutamate:sodium symporter activity
AKN93_RS00165	COG1024	Enoyl-CoA hydratase
AKN93_RS00170	COG0183	Belongs to the thiolase family
AKN93_RS00180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AKN93_RS00190	COG0583	DNA-binding transcription factor activity
AKN93_RS00205	COG1024	Enoyl-CoA hydratase
AKN93_RS00210	COG1960	acyl-CoA dehydrogenase activity
AKN93_RS00215	COG0459	protein refolding
AKN93_RS00220	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AKN93_RS00225	COG3030	protein affecting phage T7 exclusion by the F plasmid
AKN93_RS00230	COG2211	Major facilitator Superfamily
AKN93_RS00275	COG2969	positive regulation of protein catabolic process
AKN93_RS00280	COG0625	glutathione transferase activity
AKN93_RS00285	COG2857	Cytochrome c1
AKN93_RS00290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AKN93_RS00295	COG0723	plastoquinol--plastocyanin reductase activity
AKN93_RS00300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AKN93_RS00305	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AKN93_RS00310	COG0659	secondary active sulfate transmembrane transporter activity
AKN93_RS00315	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AKN93_RS00320	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AKN93_RS00330	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AKN93_RS00335	COG1538	Outer membrane efflux protein
AKN93_RS00340	COG1702	phosphate starvation-inducible protein PhoH
AKN93_RS00355	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AKN93_RS00375	COG1011	Hydrolase
AKN93_RS00390	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AKN93_RS00405	COG1965	Belongs to the frataxin family
AKN93_RS00410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AKN93_RS00415	COG3118	belongs to the thioredoxin family
AKN93_RS00425	COG0617	tRNA 3'-terminal CCA addition
AKN93_RS00435	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AKN93_RS00440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AKN93_RS00450	COG0166	Belongs to the GPI family
AKN93_RS00470	COG1362	aminopeptidase activity
AKN93_RS00475	COG1671	Belongs to the UPF0178 family
AKN93_RS00485	COG0436	Aminotransferase
AKN93_RS00495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AKN93_RS00510	COG0545	Peptidyl-prolyl cis-trans isomerase
AKN93_RS00520	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AKN93_RS00540	COG0860	N-Acetylmuramoyl-L-alanine amidase
AKN93_RS00545	COG0802	atpase or kinase
AKN93_RS00555	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AKN93_RS00560	COG1162	GTPase activity
AKN93_RS00565	COG0688	phosphatidylethanolamine metabolic process
AKN93_RS00590	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AKN93_RS00600	COG2226	methyltransferase
AKN93_RS00610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AKN93_RS00615	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AKN93_RS00625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AKN93_RS00630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AKN93_RS00645	COG0789	Transcriptional regulator
AKN93_RS00655	COG1067	ATP-dependent peptidase activity
AKN93_RS00685	COG0778	Nitroreductase
AKN93_RS00690	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AKN93_RS00695	COG0534	Mate efflux family protein
AKN93_RS00700	COG3118	belongs to the thioredoxin family
AKN93_RS00705	COG2813	Specifically methylates the guanine in position
AKN93_RS00715	COG3313	Fe-S protein
AKN93_RS00720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKN93_RS00725	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKN93_RS00730	COG0633	Ferredoxin
AKN93_RS00740	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AKN93_RS00745	COG0604	alcohol dehydrogenase
AKN93_RS00745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AKN93_RS00745	COG3321	synthase
AKN93_RS00745	COG4221	oxidoreductase activity
AKN93_RS00770	COG0545	Peptidyl-prolyl cis-trans isomerase
AKN93_RS00795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AKN93_RS00800	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AKN93_RS00805	COG0330	HflC and HflK could
AKN93_RS00810	COG0330	HflC and HflK could
AKN93_RS00815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AKN93_RS00820	COG1923	regulation of RNA biosynthetic process
AKN93_RS00840	COG1028	Short-chain dehydrogenase reductase Sdr
AKN93_RS00845	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AKN93_RS00845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AKN93_RS00850	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AKN93_RS00855	COG3258	Cytochrome c
AKN93_RS00865	COG0814	amino acid
AKN93_RS00870	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AKN93_RS00905	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AKN93_RS00910	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AKN93_RS00915	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AKN93_RS00920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AKN93_RS00925	COG0142	geranyltranstransferase activity
AKN93_RS00930	COG1970	mechanosensitive ion channel activity
AKN93_RS00935	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AKN93_RS00945	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AKN93_RS00950	COG2885	chlorophyll binding
AKN93_RS00975	COG0824	Thioesterase
AKN93_RS00980	COG2255	four-way junction helicase activity
AKN93_RS00985	COG0632	four-way junction helicase activity
AKN93_RS00990	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AKN93_RS01000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AKN93_RS01010	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AKN93_RS01020	COG0525	valine-tRNA ligase activity
AKN93_RS01030	COG4120	Belongs to the binding-protein-dependent transport system permease family
AKN93_RS01035	COG1122	ATPase activity
AKN93_RS01040	COG0471	metal ion transport
AKN93_RS01040	COG0490	domain, Protein
AKN93_RS01045	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AKN93_RS01055	COG0237	dephospho-CoA kinase activity
AKN93_RS01060	COG0134	indole-3-glycerol-phosphate synthase activity
AKN93_RS01065	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AKN93_RS01085	COG0546	phosphoglycolate phosphatase activity
AKN93_RS01090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AKN93_RS01120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AKN93_RS01125	COG0456	acetyltransferase
AKN93_RS01135	COG1722	exodeoxyribonuclease VII activity
AKN93_RS01140	COG0142	geranyltranstransferase activity
AKN93_RS01165	COG3530	Putative quorum-sensing-regulated virulence factor
AKN93_RS01170	COG0513	Belongs to the DEAD box helicase family
AKN93_RS01175	COG1509	lysine 2,3-aminomutase activity
AKN93_RS01180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AKN93_RS01200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AKN93_RS01220	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AKN93_RS01230	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AKN93_RS01235	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AKN93_RS01240	COG3178	'Phosphotransferase
AKN93_RS01245	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AKN93_RS01250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AKN93_RS01255	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AKN93_RS01265	COG0842	Transport permease protein
AKN93_RS01270	COG1129	ABC transporter
AKN93_RS01270	COG0842	Transport permease protein
AKN93_RS01275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKN93_RS01280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AKN93_RS01295	COG3079	Belongs to the UPF0149 family
AKN93_RS01300	COG0006	proline dipeptidase activity
AKN93_RS01305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AKN93_RS01315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AKN93_RS01340	COG0560	Phosphoserine phosphatase
AKN93_RS01340	COG3830	Belongs to the UPF0237 family
AKN93_RS01350	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AKN93_RS01350	COG3008	intermembrane lipid transfer
AKN93_RS01360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AKN93_RS01380	COG3150	esterase
AKN93_RS01410	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AKN93_RS01420	COG0204	Acyl-transferase
AKN93_RS01435	COG3098	single-species biofilm formation
AKN93_RS01445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AKN93_RS01455	COG0494	nUDIX hydrolase
AKN93_RS01465	COG1217	gtp-binding protein TYPA
AKN93_RS01470	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AKN93_RS01470	COG0301	tRNA thio-modification
AKN93_RS01485	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AKN93_RS01490	COG1012	belongs to the aldehyde dehydrogenase family
AKN93_RS01495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AKN93_RS01500	COG0704	Plays a role in the regulation of phosphate uptake
AKN93_RS01505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AKN93_RS01510	COG0573	inorganic phosphate transmembrane transporter activity
AKN93_RS01530	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AKN93_RS01535	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AKN93_RS01570	COG0281	malic enzyme
AKN93_RS01575	COG0254	rRNA binding
AKN93_RS01580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AKN93_RS01600	COG0427	acetyl-CoA hydrolase
AKN93_RS01615	COG1752	Esterase of the alpha-beta hydrolase superfamily
AKN93_RS01640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKN93_RS01650	COG0427	acetyl-CoA hydrolase
AKN93_RS01665	COG1752	Esterase of the alpha-beta hydrolase superfamily
AKN93_RS01690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKN93_RS01700	COG0179	Fumarylacetoacetate (FAA) hydrolase
AKN93_RS01705	COG0277	FAD linked oxidase domain protein
AKN93_RS01710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AKN93_RS01720	COG2814	Major facilitator Superfamily
AKN93_RS01730	COG0753	catalase activity
AKN93_RS01735	COG0523	cobalamin synthesis protein
AKN93_RS01760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AKN93_RS01765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AKN93_RS01775	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AKN93_RS01780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AKN93_RS01785	COG2003	Belongs to the UPF0758 family
AKN93_RS01790	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AKN93_RS01795	COG0756	dUTP diphosphatase activity
AKN93_RS01805	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AKN93_RS01825	COG1160	GTP binding
AKN93_RS01850	COG0494	nUDIX hydrolase
AKN93_RS01860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AKN93_RS01870	COG1960	acyl-CoA dehydrogenase activity
AKN93_RS01890	COG1120	ATPase activity
AKN93_RS01895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKN93_RS01900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKN93_RS01905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AKN93_RS01920	COG2855	membrane
AKN93_RS01930	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AKN93_RS01930	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AKN93_RS01940	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AKN93_RS01945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AKN93_RS01950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AKN93_RS01980	COG0730	response to heat
AKN93_RS01990	COG1414	Transcriptional regulator
AKN93_RS02000	COG4771	TonB-dependent receptor
AKN93_RS02010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AKN93_RS02020	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AKN93_RS02035	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AKN93_RS02035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AKN93_RS02045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AKN93_RS02055	COG1979	alcohol dehydrogenase
AKN93_RS02060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AKN93_RS02065	COG0583	DNA-binding transcription factor activity
AKN93_RS02080	COG0814	amino acid
AKN93_RS02085	COG1368	sulfuric ester hydrolase activity
AKN93_RS02100	COG4149	molybdate abc transporter
AKN93_RS02105	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AKN93_RS02120	COG1177	transmembrane transport
AKN93_RS02125	COG1176	ABC-type spermidine putrescine transport system, permease component I
AKN93_RS02130	COG3842	ATPase activity
AKN93_RS02145	COG3909	cytochrome
AKN93_RS02150	COG1652	LysM domain
AKN93_RS02175	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AKN93_RS02185	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AKN93_RS02190	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AKN93_RS02200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AKN93_RS02205	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AKN93_RS02210	COG4942	peptidase
AKN93_RS02215	COG0793	Belongs to the peptidase S41A family
AKN93_RS02240	COG0131	Imidazoleglycerol-phosphate dehydratase
AKN93_RS02255	COG1194	a g-specific adenine glycosylase
AKN93_RS02260	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AKN93_RS02285	COG2353	YceI-like domain
AKN93_RS02290	COG3038	cytochrome b561
AKN93_RS02295	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AKN93_RS02300	COG2193	ferroxidase activity
AKN93_RS02310	COG0126	phosphoglycerate kinase activity
AKN93_RS02315	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AKN93_RS02325	COG1040	competence protein
AKN93_RS02340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AKN93_RS02345	COG0156	8-amino-7-oxononanoate synthase activity
AKN93_RS02350	COG1073	alpha beta
AKN93_RS02350	COG2226	methyltransferase
AKN93_RS02370	COG0303	'Molybdopterin
AKN93_RS02375	COG0521	Mo-molybdopterin cofactor biosynthetic process
AKN93_RS02425	COG2815	serine threonine protein kinase
AKN93_RS02425	COG0515	serine threonine protein kinase
AKN93_RS02490	COG1561	YicC-like family, N-terminal region
AKN93_RS02495	COG4628	conserved protein (DUF2132)
AKN93_RS02500	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AKN93_RS02530	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AKN93_RS02540	COG0826	peptidase U32
AKN93_RS02550	COG0318	PFAM AMP-dependent synthetase and ligase
AKN93_RS02570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AKN93_RS02575	COG0569	domain protein
AKN93_RS02580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AKN93_RS02585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AKN93_RS02590	COG0242	peptide deformylase activity
AKN93_RS02600	COG0758	DNA mediated transformation
AKN93_RS02605	COG0009	L-threonylcarbamoyladenylate synthase
AKN93_RS02615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AKN93_RS02620	COG2239	Acts as a magnesium transporter
AKN93_RS02625	COG1285	pathogenesis
AKN93_RS02630	COG0003	Pfam Anion-transporting ATPase
AKN93_RS02640	COG1966	Carbon starvation protein
AKN93_RS02665	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AKN93_RS02670	COG0730	response to heat
AKN93_RS02675	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AKN93_RS02680	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AKN93_RS02700	COG3154	lipid carrier protein
AKN93_RS02705	COG0826	peptidase U32
AKN93_RS02710	COG0826	peptidase U32
AKN93_RS02715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AKN93_RS02730	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AKN93_RS02745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AKN93_RS02750	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AKN93_RS02755	COG0252	asparaginase activity
AKN93_RS02785	COG1132	(ABC) transporter
AKN93_RS02790	COG3620	sequence-specific DNA binding
AKN93_RS02790	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AKN93_RS02790	COG0617	tRNA 3'-terminal CCA addition
AKN93_RS02800	COG0789	Transcriptional regulator
AKN93_RS02835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AKN93_RS02840	COG0129	dihydroxy-acid dehydratase activity
AKN93_RS02855	COG3135	benzoate transporter
AKN93_RS02860	COG1178	ABC-type Fe3 transport system permease component
AKN93_RS02865	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AKN93_RS02875	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AKN93_RS02875	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AKN93_RS02885	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AKN93_RS02900	COG0742	ribosomal rna small subunit methyltransferase
AKN93_RS02905	COG0612	Peptidase, M16
AKN93_RS02910	COG0612	Peptidase, M16
AKN93_RS02925	COG2884	Cell division ATP-binding protein ftsE
AKN93_RS02930	COG2177	Part of the ABC transporter FtsEX involved in
AKN93_RS02940	COG2431	L-lysine efflux transmembrane transporter activity
AKN93_RS02945	COG0833	amino acid
AKN93_RS02955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AKN93_RS02960	COG0513	Belongs to the DEAD box helicase family
AKN93_RS02965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AKN93_RS02970	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AKN93_RS03025	COG0700	Nucleoside recognition
AKN93_RS03030	COG3023	N-Acetylmuramoyl-L-alanine amidase
AKN93_RS03040	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AKN93_RS03045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AKN93_RS03050	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AKN93_RS03055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AKN93_RS03060	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AKN93_RS03065	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AKN93_RS03070	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AKN93_RS03080	COG0356	it plays a direct role in the translocation of protons across the membrane
AKN93_RS03090	COG1475	DNA binding
AKN93_RS03095	COG1192	Involved in chromosome partitioning
AKN93_RS03110	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AKN93_RS03120	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AKN93_RS03125	COG0594	ribonuclease P activity
AKN93_RS03130	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AKN93_RS03165	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AKN93_RS03180	COG1758	RNA polymerase activity
AKN93_RS03185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AKN93_RS03205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AKN93_RS03210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AKN93_RS03215	COG2363	Small membrane protein
AKN93_RS03225	COG2022	thiamine diphosphate biosynthetic process
AKN93_RS03230	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AKN93_RS03250	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AKN93_RS03255	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AKN93_RS03265	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AKN93_RS03280	COG0248	Ppx GppA phosphatase
AKN93_RS03290	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AKN93_RS03295	COG0592	DNA-directed DNA polymerase activity
AKN93_RS03300	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AKN93_RS03310	COG0642	Histidine kinase
AKN93_RS03325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AKN93_RS03335	COG0159	tryptophan synthase activity
AKN93_RS03340	COG0133	tryptophan synthase activity
AKN93_RS03350	COG1960	acyl-CoA dehydrogenase activity
AKN93_RS03360	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AKN93_RS03365	COG0583	DNA-binding transcription factor activity
AKN93_RS03370	COG3384	dioxygenase
AKN93_RS03385	COG1289	transmembrane transporter activity
AKN93_RS03390	COG1944	ATP diphosphatase activity
AKN93_RS03395	COG2207	Transcriptional regulator
AKN93_RS03405	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AKN93_RS03415	COG0303	'Molybdopterin
AKN93_RS03420	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AKN93_RS03430	COG0642	Histidine kinase
AKN93_RS03435	COG0745	RESPONSE REGULATOR receiver
AKN93_RS03440	COG1368	sulfuric ester hydrolase activity
AKN93_RS03470	COG0084	hydrolase, TatD family'
AKN93_RS03480	COG1451	nucleotide metabolic process
AKN93_RS03485	COG0071	Belongs to the small heat shock protein (HSP20) family
AKN93_RS03505	COG0175	sulfate reduction
AKN93_RS03510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AKN93_RS03510	COG1648	precorrin-2 dehydrogenase activity
AKN93_RS03530	COG0306	phosphate transporter
AKN93_RS03535	COG1392	Phosphate transport regulator
AKN93_RS03545	COG0330	HflC and HflK could
AKN93_RS03580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AKN93_RS03590	COG0540	Belongs to the ATCase OTCase family
AKN93_RS03600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AKN93_RS03605	COG3204	pilus organization
AKN93_RS03615	COG0494	nUDIX hydrolase
AKN93_RS03620	COG1011	Hydrolase
AKN93_RS03650	COG1872	DUF167
AKN93_RS03655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AKN93_RS03660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AKN93_RS03660	COG2813	Specifically methylates the guanine in position
AKN93_RS03675	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AKN93_RS03690	COG0583	DNA-binding transcription factor activity
AKN93_RS03695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AKN93_RS03710	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AKN93_RS03730	COG0751	glycine-tRNA ligase activity
AKN93_RS03735	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AKN93_RS03755	COG0347	Belongs to the P(II) protein family
AKN93_RS03770	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AKN93_RS03775	COG3161	chorismate lyase activity
AKN93_RS03790	COG3258	Cytochrome c
AKN93_RS03795	COG2863	cytochrome
AKN93_RS03800	COG0606	chelatase, subunit chli
AKN93_RS03810	COG1028	Short-chain dehydrogenase reductase Sdr
AKN93_RS03815	COG1028	Short-chain dehydrogenase reductase Sdr
AKN93_RS03820	COG0019	diaminopimelate decarboxylase activity
AKN93_RS03825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AKN93_RS03845	COG4771	TonB-dependent receptor
AKN93_RS03855	COG4191	Histidine kinase
AKN93_RS03860	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AKN93_RS03865	COG1519	Transferase
AKN93_RS03875	COG0501	Belongs to the peptidase M48B family
AKN93_RS03885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AKN93_RS03890	COG3047	cAMP biosynthetic process
AKN93_RS03895	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AKN93_RS03900	COG1490	D-aminoacyl-tRNA deacylase activity
AKN93_RS03905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AKN93_RS03910	COG0488	(ABC) transporter
AKN93_RS03920	COG2918	glutathione biosynthetic process
AKN93_RS03925	COG2183	response to ionizing radiation
AKN93_RS03945	COG0735	belongs to the Fur family
AKN93_RS03950	COG1121	(ABC) transporter
AKN93_RS03955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AKN93_RS03970	COG2011	ABC-type metal ion transport system permease component
AKN93_RS03980	COG1765	OsmC-like protein
AKN93_RS03985	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AKN93_RS03990	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AKN93_RS03995	COG0537	adenosine 5'-monophosphoramidase activity
AKN93_RS04000	COG1981	membrane
AKN93_RS04005	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AKN93_RS04010	COG0316	Belongs to the HesB IscA family
AKN93_RS04015	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AKN93_RS04020	COG0739	heme binding
AKN93_RS04025	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AKN93_RS04055	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AKN93_RS04055	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AKN93_RS04060	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AKN93_RS04085	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AKN93_RS04105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AKN93_RS04110	COG0081	regulation of translation
AKN93_RS04115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AKN93_RS04120	COG0222	ribosome binding
AKN93_RS04125	COG0085	RNA polymerase activity
AKN93_RS04135	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AKN93_RS04140	COG0049	tRNA binding
AKN93_RS04145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AKN93_RS04150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AKN93_RS04155	COG0051	transcription antitermination factor activity, RNA binding
AKN93_RS04160	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AKN93_RS04165	COG0088	Forms part of the polypeptide exit tunnel
AKN93_RS04175	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AKN93_RS04180	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AKN93_RS04185	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AKN93_RS04190	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AKN93_RS04200	COG0255	Belongs to the universal ribosomal protein uL29 family
AKN93_RS04205	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AKN93_RS04210	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AKN93_RS04215	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AKN93_RS04225	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AKN93_RS04230	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AKN93_RS04235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AKN93_RS04240	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AKN93_RS04245	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AKN93_RS04250	COG1841	ribosomal large subunit assembly
AKN93_RS04255	COG0200	Binds to the 23S rRNA
AKN93_RS04270	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AKN93_RS04275	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AKN93_RS04280	COG0202	RNA polymerase activity
AKN93_RS04285	COG0203	ribosomal protein L17
AKN93_RS04295	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AKN93_RS04315	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AKN93_RS04330	COG2081	HI0933 family
AKN93_RS04340	COG3263	regulation of cellular component size
AKN93_RS04345	COG3264	Mechanosensitive ion channel
AKN93_RS04345	COG1196	nuclear chromosome segregation
AKN93_RS04350	COG0676	glucose-6-phosphate 1-epimerase activity
AKN93_RS04375	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AKN93_RS04380	COG2176	DNA-directed DNA polymerase activity
AKN93_RS04390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AKN93_RS04415	COG0697	spore germination
AKN93_RS04420	COG2207	Transcriptional regulator
AKN93_RS04420	COG1917	Cupin 2, conserved barrel domain protein
AKN93_RS04425	COG0113	porphobilinogen synthase activity
AKN93_RS04430	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AKN93_RS04445	COG1960	acyl-CoA dehydrogenase activity
AKN93_RS04455	COG0318	PFAM AMP-dependent synthetase and ligase
AKN93_RS04460	COG4191	Histidine kinase
AKN93_RS04465	COG4566	intracellular signal transduction
AKN93_RS04470	COG0617	tRNA 3'-terminal CCA addition
AKN93_RS04495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AKN93_RS04510	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AKN93_RS04515	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AKN93_RS04520	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AKN93_RS04535	COG1346	cytolysis
AKN93_RS04540	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AKN93_RS04540	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AKN93_RS04545	COG4989	oxidoreductase activity
AKN93_RS04555	COG1301	dicarboxylic acid transport
AKN93_RS04570	COG4659	FMN binding
AKN93_RS04575	COG4658	electron transport chain
AKN93_RS04585	COG2878	Part of a membrane complex involved in electron transport
AKN93_RS04590	COG4657	Part of a membrane complex involved in electron transport
AKN93_RS04600	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AKN93_RS04620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AKN93_RS04625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AKN93_RS04635	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AKN93_RS04640	COG0501	Belongs to the peptidase M48B family
AKN93_RS04650	COG1643	Atp-dependent helicase
AKN93_RS04675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AKN93_RS04680	COG1802	Transcriptional regulator
AKN93_RS04690	COG0372	Belongs to the citrate synthase family
AKN93_RS04695	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AKN93_RS04705	COG2264	protein methyltransferase activity
AKN93_RS04715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKN93_RS04725	COG0318	PFAM AMP-dependent synthetase and ligase
AKN93_RS04730	COG0183	Belongs to the thiolase family
AKN93_RS04745	COG3148	PFAM DTW domain containing protein
AKN93_RS04760	COG2873	o-acetylhomoserine
AKN93_RS04770	COG1690	Belongs to the RtcB family
AKN93_RS04775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AKN93_RS04790	COG0288	reversible hydration of carbon dioxide
AKN93_RS04805	COG0022	dehydrogenase e1 component
AKN93_RS04810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AKN93_RS04830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AKN93_RS04840	COG1028	Short-chain dehydrogenase reductase Sdr
AKN93_RS04845	COG0671	phosphoesterase, PA-phosphatase related
AKN93_RS04850	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AKN93_RS04855	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AKN93_RS04860	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AKN93_RS04870	COG1607	acyl-coa hydrolase
AKN93_RS04880	COG0861	Integral membrane protein TerC family
AKN93_RS04890	COG0488	(ABC) transporter
AKN93_RS04915	COG0181	hydroxymethylbilane synthase activity
AKN93_RS04940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AKN93_RS04945	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AKN93_RS04950	COG3956	TIGRFAM MazG family protein
AKN93_RS04955	COG3122	Protein conserved in bacteria
AKN93_RS04965	COG3258	Cytochrome c
AKN93_RS04970	COG0268	Binds directly to 16S ribosomal RNA
AKN93_RS04975	COG0728	peptidoglycan biosynthetic process
AKN93_RS04980	COG0196	riboflavin kinase activity
AKN93_RS04985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AKN93_RS04995	COG1047	Peptidyl-prolyl cis-trans
AKN93_RS05000	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AKN93_RS05015	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AKN93_RS05030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AKN93_RS05055	COG4574	serine-type endopeptidase inhibitor activity
AKN93_RS05065	COG0322	excinuclease ABC activity
AKN93_RS05080	COG3100	YcgL domain-containing protein
AKN93_RS05085	COG1555	photosystem II stabilization
AKN93_RS05100	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AKN93_RS05105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AKN93_RS05115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AKN93_RS05145	COG0714	Associated with various cellular activities
AKN93_RS05150	COG0564	pseudouridine synthase activity
AKN93_RS05155	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AKN93_RS05160	COG2894	cell division
AKN93_RS05165	COG0850	regulation of cytokinetic process
AKN93_RS05170	COG1560	Kdo2-lipid A biosynthetic process
AKN93_RS05180	COG2853	Lipoprotein
AKN93_RS05195	COG0489	protein tyrosine kinase activity
AKN93_RS05200	COG1278	Cold shock
AKN93_RS05205	COG0717	Belongs to the dCTP deaminase family
AKN93_RS05230	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AKN93_RS05260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AKN93_RS05270	COG0859	PFAM glycosyl transferase family 9
AKN93_RS05275	COG0859	PFAM glycosyl transferase family 9
AKN93_RS05280	COG0438	transferase activity, transferring glycosyl groups
AKN93_RS05305	COG2192	nodulation
AKN93_RS05310	COG0438	transferase activity, transferring glycosyl groups
AKN93_RS05340	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AKN93_RS05355	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AKN93_RS05380	COG0438	transferase activity, transferring glycosyl groups
AKN93_RS05385	COG0438	transferase activity, transferring glycosyl groups
AKN93_RS05405	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AKN93_RS05440	COG1252	NADH dehydrogenase
AKN93_RS05455	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AKN93_RS05460	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKN93_RS05475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKN93_RS05480	COG1077	Cell shape determining protein MreB Mrl
AKN93_RS05485	COG1792	Involved in formation and maintenance of cell shape
AKN93_RS05495	COG0424	maF-like protein
AKN93_RS05500	COG1530	ribonuclease E activity
AKN93_RS05510	COG0497	DNA recombination
AKN93_RS05515	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AKN93_RS05520	COG0443	Heat shock 70 kDa protein
AKN93_RS05525	COG0484	heat shock protein binding
AKN93_RS05530	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AKN93_RS05550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AKN93_RS05575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AKN93_RS05580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AKN93_RS05585	COG0149	triose-phosphate isomerase activity
AKN93_RS05600	COG0779	Required for maturation of 30S ribosomal subunits
AKN93_RS05605	COG0195	Participates in both transcription termination and antitermination
AKN93_RS05610	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AKN93_RS05615	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AKN93_RS05620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AKN93_RS05625	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AKN93_RS05630	COG1185	polyribonucleotide nucleotidyltransferase activity
AKN93_RS05640	COG0501	Belongs to the peptidase M48B family
AKN93_RS05645	COG3091	SprT-like family
AKN93_RS05660	COG0436	Aminotransferase
AKN93_RS05685	COG1104	cysteine desulfurase activity
AKN93_RS05695	COG0316	Belongs to the HesB IscA family
AKN93_RS05700	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AKN93_RS05740	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AKN93_RS05745	COG0124	histidyl-tRNA synthetase
AKN93_RS05760	COG1160	GTP binding
AKN93_RS05775	COG2832	Protein of unknown function (DUF454)
AKN93_RS05795	COG0446	pyridine nucleotide-disulphide oxidoreductase
AKN93_RS05795	COG1902	pentaerythritol trinitrate reductase activity
AKN93_RS05800	COG1530	ribonuclease E activity
AKN93_RS05820	COG0424	maF-like protein
AKN93_RS05825	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AKN93_RS05835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AKN93_RS05840	COG0336	Belongs to the RNA methyltransferase TrmD family
AKN93_RS05850	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AKN93_RS05860	COG2823	Periplasmic or secreted lipoprotein
AKN93_RS05870	COG0792	nuclease activity
AKN93_RS05875	COG3107	peptidoglycan biosynthetic process
AKN93_RS05885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AKN93_RS05900	COG3223	Belongs to the PsiE family
AKN93_RS05910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AKN93_RS05920	COG3028	Belongs to the UPF0307 family
AKN93_RS05925	COG0312	modulator of DNA gyrase
AKN93_RS05930	COG0028	Belongs to the TPP enzyme family
AKN93_RS05945	COG1183	phosphatidylcholine synthase activity
AKN93_RS05975	COG0500	methyltransferase
AKN93_RS05995	COG0135	phosphoribosylanthranilate isomerase activity
AKN93_RS06000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AKN93_RS06005	COG0285	dihydrofolate synthase activity
AKN93_RS06015	COG1286	toxin biosynthetic process
AKN93_RS06030	COG2925	Exonuclease
AKN93_RS06045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AKN93_RS06050	COG0544	peptidyl-prolyl cis-trans isomerase activity
AKN93_RS06060	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AKN93_RS06065	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AKN93_RS06075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AKN93_RS06080	COG3089	Belongs to the UPF0270 family
AKN93_RS06085	COG0431	NADPH-dependent FMN reductase
AKN93_RS06090	COG2056	Na+-H+ antiporter family
AKN93_RS06095	COG2837	iron assimilation
AKN93_RS06100	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AKN93_RS06110	COG2914	Belongs to the UPF0125 (RnfH) family
AKN93_RS06115	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AKN93_RS06125	COG2326	polyphosphate kinase activity
AKN93_RS06130	COG3081	Nucleoid-associated protein
AKN93_RS06145	COG3171	Protein conserved in bacteria
AKN93_RS06155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AKN93_RS06175	COG2610	gluconate transmembrane transporter activity
AKN93_RS06185	COG2084	Dehydrogenase
AKN93_RS06190	COG3622	Belongs to the hyi family
AKN93_RS06235	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AKN93_RS06240	COG0352	thiamine-phosphate diphosphorylase activity
AKN93_RS06245	COG0351	phosphomethylpyrimidine kinase
AKN93_RS06245	COG0352	thiamine-phosphate diphosphorylase activity
AKN93_RS06260	COG0495	leucyl-tRNA aminoacylation
AKN93_RS06270	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AKN93_RS06270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AKN93_RS06280	COG1196	nuclear chromosome segregation
AKN93_RS06285	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AKN93_RS06290	COG1546	Belongs to the CinA family
AKN93_RS06300	COG2137	regulation of response to DNA damage stimulus
AKN93_RS06315	COG0513	Belongs to the DEAD box helicase family
AKN93_RS06320	COG1946	Acyl-CoA thioesterase
AKN93_RS06355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AKN93_RS06360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AKN93_RS06365	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AKN93_RS06370	COG0772	Belongs to the SEDS family
AKN93_RS06380	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AKN93_RS06385	COG1181	Belongs to the D-alanine--D-alanine ligase family
AKN93_RS06400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AKN93_RS06405	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AKN93_RS06415	COG0653	protein targeting
AKN93_RS06425	COG0494	nUDIX hydrolase
AKN93_RS06430	COG2096	Adenosyltransferase
AKN93_RS06440	COG1666	GTP binding
AKN93_RS06445	COG0322	excinuclease ABC activity
AKN93_RS06460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKN93_RS06465	COG0360	Binds together with S18 to 16S ribosomal RNA
AKN93_RS06480	COG0359	binds to the 23S rRNA
AKN93_RS06485	COG0305	Participates in initiation and elongation during chromosome replication
AKN93_RS06495	COG5002	protein histidine kinase activity
AKN93_RS06495	COG2205	protein histidine kinase activity
AKN93_RS06495	COG0784	Response regulator, receiver
AKN93_RS06505	COG0138	bifunctional purine biosynthesis protein purh
AKN93_RS06535	COG2135	peptidase activity
AKN93_RS06545	COG1660	Displays ATPase and GTPase activities
AKN93_RS06560	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AKN93_RS06585	COG3201	nicotinamide mononucleotide transporter
AKN93_RS06595	COG1846	Transcriptional regulator
AKN93_RS06600	COG2814	Major facilitator Superfamily
AKN93_RS06605	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AKN93_RS06620	COG1805	sodium ion transport
AKN93_RS06645	COG1477	protein flavinylation
AKN93_RS06655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AKN93_RS06665	COG4591	ABC-type transport system involved in lipoprotein release permease component
AKN93_RS06680	COG0436	Aminotransferase
AKN93_RS06685	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AKN93_RS06695	COG4536	flavin adenine dinucleotide binding
AKN93_RS06705	COG1399	metal-binding, possibly nucleic acid-binding protein
AKN93_RS06710	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AKN93_RS06715	COG0416	fatty acid biosynthetic process
AKN93_RS06730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AKN93_RS06735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AKN93_RS06740	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AKN93_RS06745	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AKN93_RS06750	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AKN93_RS06765	COG0084	hydrolase, TatD family'
AKN93_RS06770	COG1643	Atp-dependent helicase
AKN93_RS06775	COG0826	peptidase U32
AKN93_RS06785	COG1214	PFAM Peptidase M22, glycoprotease
AKN93_RS06790	COG0742	ribosomal rna small subunit methyltransferase
AKN93_RS06810	COG0564	pseudouridine synthase activity
AKN93_RS06825	COG3720	iron ion transport
AKN93_RS06835	COG0848	biopolymer transport protein
AKN93_RS06840	COG4558	Periplasmic binding protein
AKN93_RS06845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKN93_RS06850	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AKN93_RS06870	COG0165	Argininosuccinate lyase
AKN93_RS06880	COG0530	calcium, potassium:sodium antiporter activity
AKN93_RS06885	COG0471	metal ion transport
AKN93_RS06890	COG0513	Belongs to the DEAD box helicase family
AKN93_RS06910	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AKN93_RS06925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AKN93_RS06985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AKN93_RS07005	COG3206	protein involved in exopolysaccharide biosynthesis
AKN93_RS07005	COG0489	protein tyrosine kinase activity
AKN93_RS07025	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AKN93_RS07050	COG0438	transferase activity, transferring glycosyl groups
AKN93_RS07055	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AKN93_RS07065	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AKN93_RS07070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AKN93_RS07095	COG1968	undecaprenyl-diphosphatase activity
AKN93_RS07125	COG1252	NADH dehydrogenase
AKN93_RS07135	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AKN93_RS07145	COG0148	phosphopyruvate hydratase activity
AKN93_RS07150	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AKN93_RS07155	COG0504	CTP synthase activity
AKN93_RS07170	COG2951	lytic endotransglycosylase activity
AKN93_RS07180	COG1686	Belongs to the peptidase S11 family
AKN93_RS07190	COG0321	lipoyl(octanoyl) transferase activity
AKN93_RS07195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AKN93_RS07205	COG2264	protein methyltransferase activity
AKN93_RS07230	COG0730	response to heat
AKN93_RS07235	COG0514	ATP-dependent DNA helicase (RecQ)
AKN93_RS07240	COG2076	Multidrug Resistance protein
AKN93_RS07250	COG5592	hemerythrin HHE cation binding domain
AKN93_RS07255	COG0602	queuosine metabolic process
AKN93_RS07260	COG0720	synthase
AKN93_RS07280	COG2823	Periplasmic or secreted lipoprotein
AKN93_RS07285	COG0363	glucosamine-6-phosphate deaminase activity
AKN93_RS07300	COG2967	ApaG domain
AKN93_RS07305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AKN93_RS07310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AKN93_RS07320	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AKN93_RS07330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AKN93_RS07340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AKN93_RS07345	COG0795	lipopolysaccharide-transporting ATPase activity
AKN93_RS07350	COG0795	lipopolysaccharide-transporting ATPase activity
AKN93_RS07355	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AKN93_RS07360	COG2027	D-alanyl-D-alanine carboxypeptidase
AKN93_RS07370	COG2847	Copper chaperone PCu(A)C
AKN93_RS07375	COG1278	Cold shock
AKN93_RS07380	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AKN93_RS07385	COG0542	response to heat
AKN93_RS07400	COG2030	dehydratase
AKN93_RS07405	COG0318	PFAM AMP-dependent synthetase and ligase
AKN93_RS07410	COG0589	response to stress
AKN93_RS07415	COG1252	NADH dehydrogenase
AKN93_RS07425	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AKN93_RS07435	COG0148	phosphopyruvate hydratase activity
AKN93_RS07440	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AKN93_RS07445	COG0504	CTP synthase activity
AKN93_RS07470	COG1199	ATP-dependent helicase activity
AKN93_RS07480	COG0167	dihydroorotate dehydrogenase activity
AKN93_RS07485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AKN93_RS07495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AKN93_RS07505	COG3243	poly(R)-hydroxyalkanoic acid synthase
AKN93_RS07515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AKN93_RS07530	COG0800	Aldolase
AKN93_RS07545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AKN93_RS07550	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AKN93_RS07555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AKN93_RS07570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AKN93_RS07575	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AKN93_RS07590	COG2989	Protein conserved in bacteria
AKN93_RS07595	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AKN93_RS07600	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AKN93_RS07605	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AKN93_RS07610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AKN93_RS07615	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AKN93_RS07620	COG0072	phenylalanine-tRNA ligase activity
AKN93_RS07625	COG0776	regulation of translation
AKN93_RS07660	COG0693	protein deglycase activity
AKN93_RS07670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AKN93_RS07690	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AKN93_RS07690	COG0515	serine threonine protein kinase
AKN93_RS07740	COG0542	response to heat
AKN93_RS07750	COG0189	ligase activity
AKN93_RS07765	COG2223	nitrite transmembrane transporter activity
AKN93_RS07785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AKN93_RS07795	COG2321	neutral zinc metallopeptidase
AKN93_RS07800	COG4988	ABC transporter
AKN93_RS07805	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AKN93_RS07815	COG0328	RNA-DNA hybrid ribonuclease activity
AKN93_RS07820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AKN93_RS07890	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AKN93_RS07900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AKN93_RS07905	COG1115	amino acid carrier protein
AKN93_RS07925	COG0425	Belongs to the sulfur carrier protein TusA family
AKN93_RS07930	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AKN93_RS07935	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AKN93_RS07955	COG0308	aminopeptidase N
AKN93_RS07970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AKN93_RS07985	COG1335	isochorismatase
AKN93_RS07990	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AKN93_RS07995	COG4181	ATPase activity
AKN93_RS08010	COG0402	S-adenosylhomocysteine deaminase activity
AKN93_RS08050	COG0418	dihydroorotase activity
AKN93_RS08055	COG0137	argininosuccinate synthase activity
AKN93_RS08060	COG0346	lactoylglutathione lyase activity
AKN93_RS08075	COG1028	Short-chain dehydrogenase reductase Sdr
AKN93_RS08085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AKN93_RS08090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AKN93_RS08095	COG2252	PERMEase
AKN93_RS08110	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AKN93_RS08115	COG0066	3-isopropylmalate dehydratase activity
AKN93_RS08140	COG0668	transmembrane transport
AKN93_RS08145	COG4133	protoheme IX ABC transporter activity
AKN93_RS08170	COG1138	Cytochrome C-type biogenesis protein
AKN93_RS08190	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AKN93_RS08195	COG1360	Flagellar Motor Protein
AKN93_RS08210	COG3133	Outer membrane lipoprotein
AKN93_RS08255	COG1025	Belongs to the peptidase M16 family
AKN93_RS08260	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AKN93_RS08260	COG0116	Belongs to the methyltransferase superfamily
AKN93_RS08285	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AKN93_RS08315	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AKN93_RS08320	COG1074	ATP-dependent DNA helicase activity
AKN93_RS08325	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AKN93_RS08330	COG0393	Putative heavy-metal-binding
AKN93_RS08340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AKN93_RS08365	COG1024	Enoyl-CoA hydratase
AKN93_RS08380	COG2204	response regulator
AKN93_RS08385	COG4191	Histidine kinase
AKN93_RS08385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AKN93_RS08415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKN93_RS08420	COG0481	GTPase activity
AKN93_RS08430	COG0571	ribonuclease III activity
AKN93_RS08435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AKN93_RS08440	COG1381	Involved in DNA repair and RecF pathway recombination
AKN93_RS08445	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AKN93_RS08465	COG1131	(ABC) transporter
AKN93_RS08470	COG0842	Transport permease protein
AKN93_RS08475	COG0791	NLP P60 protein
AKN93_RS08480	COG0791	NLP P60 protein
AKN93_RS08485	COG0133	tryptophan synthase activity
AKN93_RS08495	COG0642	Histidine kinase
AKN93_RS08505	COG0745	RESPONSE REGULATOR receiver
AKN93_RS08510	COG2350	Protein conserved in bacteria
AKN93_RS08515	COG2917	probably involved in intracellular septation
AKN93_RS08520	COG0613	PHP domain protein
AKN93_RS08525	COG0009	L-threonylcarbamoyladenylate synthase
AKN93_RS08530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AKN93_RS08535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AKN93_RS08545	COG0535	radical SAM domain protein
AKN93_RS08555	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AKN93_RS08610	COG2205	protein histidine kinase activity
AKN93_RS08610	COG0784	Response regulator, receiver
AKN93_RS08630	COG1397	ADP-ribosylglycohydrolase
AKN93_RS08635	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AKN93_RS08645	COG0419	ATPase involved in DNA repair
AKN93_RS08650	COG0420	3'-5' exonuclease activity
AKN93_RS08660	COG0628	permease
AKN93_RS08670	COG0625	glutathione transferase activity
AKN93_RS08690	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AKN93_RS08695	COG5002	protein histidine kinase activity
AKN93_RS08695	COG2205	protein histidine kinase activity
AKN93_RS08695	COG0784	Response regulator, receiver
AKN93_RS08700	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AKN93_RS08710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AKN93_RS08715	COG2814	Major facilitator Superfamily
AKN93_RS08735	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AKN93_RS08740	COG0585	pseudouridine synthase activity
AKN93_RS08745	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AKN93_RS08755	COG2911	Protein conserved in bacteria
AKN93_RS08760	COG0729	surface antigen
AKN93_RS08765	COG0708	Exodeoxyribonuclease III
AKN93_RS08770	COG3781	membrane
AKN93_RS08775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AKN93_RS08780	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AKN93_RS08785	COG1858	cytochrome C peroxidase
AKN93_RS08830	COG0037	tRNA processing
AKN93_RS08850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AKN93_RS08860	COG0560	Phosphoserine phosphatase
AKN93_RS08880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AKN93_RS08895	COG4953	penicillin-binding protein 1C
AKN93_RS08905	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AKN93_RS08910	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AKN93_RS08915	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AKN93_RS08920	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AKN93_RS08925	COG5007	Belongs to the BolA IbaG family
AKN93_RS08945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AKN93_RS08950	COG1127	ABC transporter
AKN93_RS08960	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AKN93_RS08970	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AKN93_RS08975	COG1137	ATPase activity
AKN93_RS08990	COG1132	(ABC) transporter
AKN93_RS09015	COG0730	response to heat
AKN93_RS09030	COG1024	Enoyl-CoA hydratase
AKN93_RS09035	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AKN93_RS09045	COG2010	Cytochrome c
AKN93_RS09050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AKN93_RS09050	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AKN93_RS09055	COG0023	Translation Initiation Factor
AKN93_RS09060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AKN93_RS09070	COG2119	membrane
AKN93_RS09075	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AKN93_RS09080	COG0675	Transposase, IS605 OrfB family
AKN93_RS09100	COG0500	methyltransferase
AKN93_RS09120	COG1335	isochorismatase
AKN93_RS09180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AKN93_RS09185	COG2373	Large extracellular alpha-helical protein
AKN93_RS09200	COG0433	COG0433 Predicted ATPase
AKN93_RS09205	COG0788	formyltetrahydrofolate deformylase activity
AKN93_RS09210	COG2853	Lipoprotein
AKN93_RS09215	COG0215	cysteine-tRNA ligase activity
AKN93_RS09220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AKN93_RS09225	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AKN93_RS09230	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AKN93_RS09235	COG2031	fatty acid transporter
AKN93_RS09240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AKN93_RS09245	COG3115	cell septum assembly
AKN93_RS09250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AKN93_RS09255	COG2824	Alkylphosphonate utilization operon protein PhnA
AKN93_RS09265	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AKN93_RS09270	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AKN93_RS09275	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AKN93_RS09280	COG1605	Chorismate mutase
AKN93_RS09280	COG0077	Prephenate dehydratase
AKN93_RS09295	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AKN93_RS09300	COG1132	(ABC) transporter
AKN93_RS09310	COG0628	permease
AKN93_RS09320	COG0271	Belongs to the BolA IbaG family
AKN93_RS09350	COG0848	biopolymer transport protein
AKN93_RS09355	COG0811	peptide transport
AKN93_RS09360	COG0811	peptide transport
AKN93_RS09370	COG0121	glutamine amidotransferase
AKN93_RS09380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AKN93_RS09405	COG0582	viral genome integration into host DNA
AKN93_RS09465	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AKN93_RS09500	COG0730	response to heat
AKN93_RS09505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AKN93_RS09510	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AKN93_RS09520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AKN93_RS09525	COG4208	sulfate ABC transporter
AKN93_RS09535	COG0469	pyruvate kinase activity
AKN93_RS09540	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AKN93_RS09545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AKN93_RS09550	COG3842	ATPase activity
AKN93_RS09570	COG0730	response to heat
AKN93_RS09575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AKN93_RS09580	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AKN93_RS09590	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AKN93_RS09595	COG4208	sulfate ABC transporter
AKN93_RS09605	COG0469	pyruvate kinase activity
AKN93_RS09610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AKN93_RS09615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AKN93_RS09620	COG3842	ATPase activity
AKN93_RS09640	COG2885	chlorophyll binding
AKN93_RS09650	COG0427	acetyl-CoA hydrolase
AKN93_RS09675	COG0513	Belongs to the DEAD box helicase family
AKN93_RS09690	COG2212	antiporter activity
AKN93_RS09700	COG0651	ATP synthesis coupled electron transport
AKN93_RS09705	COG1006	Multisubunit Na H antiporter MnhC subunit
AKN93_RS09710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AKN93_RS09710	COG2111	Na H antiporter
AKN93_RS09715	COG0604	alcohol dehydrogenase
AKN93_RS09730	COG0556	nucleotide-excision repair
AKN93_RS09740	COG1136	(ABC) transporter
AKN93_RS09755	COG2996	Protein conserved in bacteria
AKN93_RS09765	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AKN93_RS09770	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AKN93_RS09775	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AKN93_RS09780	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AKN93_RS09790	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AKN93_RS09800	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AKN93_RS09810	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AKN93_RS09815	COG0233	cytoplasmic translational termination
AKN93_RS09820	COG0528	UMP kinase activity
AKN93_RS09825	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AKN93_RS09830	COG0052	Belongs to the universal ribosomal protein uS2 family
AKN93_RS09835	COG0024	Methionine aminopeptidase
AKN93_RS09840	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AKN93_RS09845	COG1393	Belongs to the ArsC family
AKN93_RS09850	COG2171	N-acyltransferase activity
AKN93_RS09855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AKN93_RS09860	COG2166	iron-sulfur cluster assembly
AKN93_RS09895	COG2814	Major facilitator Superfamily
AKN93_RS09905	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AKN93_RS09910	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AKN93_RS09920	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AKN93_RS09925	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AKN93_RS09935	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AKN93_RS09940	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AKN93_RS09955	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AKN93_RS09970	COG0604	alcohol dehydrogenase
AKN93_RS09975	COG0616	signal peptide processing
AKN93_RS10000	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AKN93_RS10005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AKN93_RS10010	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AKN93_RS10015	COG2835	tetraacyldisaccharide 4'-kinase activity
AKN93_RS10020	COG1663	tetraacyldisaccharide 4'-kinase activity
AKN93_RS10025	COG2333	competence protein COMEC
AKN93_RS10025	COG0658	competence protein
AKN93_RS10035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AKN93_RS10045	COG5016	pyruvate
AKN93_RS10045	COG0511	ligase activity, forming carbon-carbon bonds
AKN93_RS10050	COG3630	sodium ion export across plasma membrane
AKN93_RS10055	COG2239	Acts as a magnesium transporter
AKN93_RS10085	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AKN93_RS10095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AKN93_RS10105	COG0037	tRNA processing
AKN93_RS10110	COG2814	Major facilitator Superfamily
AKN93_RS10115	COG0284	orotidine-5'-phosphate decarboxylase activity
AKN93_RS10120	COG0114	fumarate hydratase activity
AKN93_RS10125	COG0730	response to heat
AKN93_RS10150	COG1862	Preprotein translocase
AKN93_RS10160	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AKN93_RS10170	COG2259	Doxx family
AKN93_RS10175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AKN93_RS10180	COG2366	antibiotic biosynthetic process
AKN93_RS10185	COG2885	chlorophyll binding
AKN93_RS10200	COG0400	carboxylic ester hydrolase activity
AKN93_RS10205	COG0513	Belongs to the DEAD box helicase family
AKN93_RS10210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AKN93_RS10220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AKN93_RS10230	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AKN93_RS10235	COG0425	Belongs to the sulfur carrier protein TusA family
AKN93_RS10240	COG4783	chaperone-mediated protein folding
AKN93_RS10245	COG2855	membrane
AKN93_RS10250	COG2814	Major facilitator Superfamily
AKN93_RS10265	COG1272	protein, Hemolysin III
AKN93_RS10280	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AKN93_RS10290	COG0456	acetyltransferase
AKN93_RS10315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AKN93_RS10320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKN93_RS10325	COG1120	ATPase activity
AKN93_RS10335	COG1492	cobalamin metabolic process
AKN93_RS10340	COG0778	Nitroreductase
AKN93_RS10360	COG0583	DNA-binding transcription factor activity
AKN93_RS10400	COG0318	PFAM AMP-dependent synthetase and ligase
AKN93_RS10405	COG1960	acyl-CoA dehydrogenase activity
AKN93_RS10410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AKN93_RS10415	COG1250	3-hydroxyacyl-CoA dehydrogenase
AKN93_RS10415	COG1024	Enoyl-CoA hydratase
AKN93_RS10440	COG0789	Transcriptional regulator
AKN93_RS10445	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AKN93_RS10470	COG0045	succinate-CoA ligase (ADP-forming) activity
AKN93_RS10490	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AKN93_RS10505	COG2009	succinate dehydrogenase
AKN93_RS10525	COG2084	Dehydrogenase
AKN93_RS10535	COG3278	Belongs to the heme-copper respiratory oxidase family
AKN93_RS10550	COG2010	Cytochrome c
AKN93_RS10565	COG2217	Heavy metal translocating P-type atpase
AKN93_RS10590	COG2175	clavaminate synthase activity
AKN93_RS10595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AKN93_RS10600	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AKN93_RS10605	COG4521	taurine ABC transporter
AKN93_RS10610	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AKN93_RS10615	COG0492	ferredoxin-NADP+ reductase activity
AKN93_RS10635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AKN93_RS10655	COG0776	regulation of translation
AKN93_RS10660	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AKN93_RS10660	COG0316	Belongs to the HesB IscA family
AKN93_RS10665	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
AKN93_RS10685	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AKN93_RS10690	COG2840	Smr protein MutS2
AKN93_RS10720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AKN93_RS10725	COG0018	arginyl-trna synthetase
AKN93_RS10740	COG4206	TonB-dependent receptor
AKN93_RS10750	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AKN93_RS10760	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AKN93_RS10770	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AKN93_RS10770	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AKN93_RS10775	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AKN93_RS10785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AKN93_RS10805	COG1309	transcriptional regulator
AKN93_RS10830	COG0183	Belongs to the thiolase family
AKN93_RS10835	COG1024	Enoyl-CoA hydratase
AKN93_RS10835	COG1250	3-hydroxyacyl-CoA dehydrogenase
AKN93_RS10840	COG0589	response to stress
AKN93_RS10845	COG0405	Gamma-glutamyltransferase
AKN93_RS10850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AKN93_RS10855	COG0488	(ABC) transporter
AKN93_RS10870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AKN93_RS10875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AKN93_RS10885	COG0741	lytic transglycosylase activity
AKN93_RS10885	COG1388	LysM domain
AKN93_RS10895	COG4166	transmembrane transport
AKN93_RS10900	COG4174	ABC transporter (Permease)
AKN93_RS10905	COG4239	(ABC) transporter, permease
AKN93_RS10910	COG4172	Belongs to the ABC transporter superfamily
AKN93_RS10925	COG0753	catalase activity
AKN93_RS10930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AKN93_RS10935	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AKN93_RS10940	COG0482	sulfurtransferase activity
AKN93_RS10945	COG2915	High frequency lysogenization protein hflD homolog
AKN93_RS10950	COG0697	spore germination
AKN93_RS10960	COG2850	peptidyl-arginine hydroxylation
AKN93_RS10965	COG2153	protein acetylation
AKN93_RS10985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AKN93_RS10995	COG2226	methyltransferase
AKN93_RS11010	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AKN93_RS11015	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AKN93_RS11015	COG0519	Catalyzes the synthesis of GMP from XMP
AKN93_RS11025	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AKN93_RS11030	COG2860	membrane
AKN93_RS11035	COG0644	oxidoreductase
AKN93_RS11140	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AKN93_RS11170	COG0860	N-Acetylmuramoyl-L-alanine amidase
AKN93_RS11170	COG3409	Peptidoglycan-binding domain 1 protein
AKN93_RS11265	COG3038	cytochrome b561
AKN93_RS11345	COG0741	lytic transglycosylase activity
AKN93_RS11345	COG0739	heme binding
AKN93_RS11345	COG1196	nuclear chromosome segregation
