TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 Pfam PF00575 S1 RNA binding domain 565 640 1.3E-6 T 22-04-2016 IPR003029 S1 domain GO:0003676 TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 SUPERFAMILY SSF50249 466 560 1.76E-111 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 SUPERFAMILY SSF50249 125 431 1.76E-111 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 6 643 1.5E-186 T 22-04-2016 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 PANTHER PTHR23355 23 649 1.3E-294 T 22-04-2016 TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 SUPERFAMILY SSF50249 8 78 3.43E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 Pfam PF08206 Ribonuclease B OB domain 24 80 3.3E-16 T 22-04-2016 IPR013223 Ribonuclease B, N-terminal OB domain TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 SMART SM00955 192 520 2.8E-120 T 22-04-2016 TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 TIGRFAM TIGR02062 RNase_B: exoribonuclease II 1 644 4.4E-274 T 22-04-2016 IPR011804 Ribonuclease II GO:0003723|GO:0006401|GO:0008859 TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 SUPERFAMILY SSF50249 565 643 2.4E-15 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 Hamap MF_01036 Exoribonuclease 2 [rnb]. 1 647 40.442 T 22-04-2016 IPR011804 Ribonuclease II GO:0003723|GO:0006401|GO:0008859 TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 PANTHER PTHR23355:SF37 23 649 1.3E-294 T 22-04-2016 TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 SMART SM00357 23 80 1.4E-12 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 Pfam PF00773 RNB domain 192 519 4.2E-85 T 22-04-2016 TOLA_RS15485 5b539eae43d87126249b82fdf3b1c7de 686 ProSitePatterns PS01175 Ribonuclease II family signature. 487 511 - T 22-04-2016 IPR022966 Ribonuclease II/R, conserved site TOLA_RS08680 a6f4d41b9ae004cd7cc78379d56eec8b 319 PANTHER PTHR22925:SF12 5 313 4.8E-96 T 22-04-2016 TOLA_RS08680 a6f4d41b9ae004cd7cc78379d56eec8b 319 SUPERFAMILY SSF75005 4 314 8.58E-70 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain TOLA_RS08680 a6f4d41b9ae004cd7cc78379d56eec8b 319 Gene3D G3DSA:2.115.10.20 2 314 1.4E-95 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain TOLA_RS08680 a6f4d41b9ae004cd7cc78379d56eec8b 319 Pfam PF04616 Glycosyl hydrolases family 43 4 307 1.0E-70 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 TOLA_RS08680 a6f4d41b9ae004cd7cc78379d56eec8b 319 PIRSF PIRSF025414 1 318 8.2E-140 T 22-04-2016 IPR016828 Alpha-L-arabinofuranosidase KEGG: 00520+3.2.1.55|UniPathway: UPA00667 TOLA_RS08680 a6f4d41b9ae004cd7cc78379d56eec8b 319 PANTHER PTHR22925 5 313 4.8E-96 T 22-04-2016 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 TOLA_RS11540 4ee71ac721ef5cb739811a297d82f7ef 421 SUPERFAMILY SSF116734 208 419 1.8E-26 T 22-04-2016 TOLA_RS11540 4ee71ac721ef5cb739811a297d82f7ef 421 SUPERFAMILY SSF116734 17 211 4.41E-37 T 22-04-2016 TOLA_RS11540 4ee71ac721ef5cb739811a297d82f7ef 421 PANTHER PTHR30408 157 418 1.5E-35 T 22-04-2016 TOLA_RS11540 4ee71ac721ef5cb739811a297d82f7ef 421 Pfam PF01420 Type I restriction modification DNA specificity domain 25 188 2.4E-23 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TOLA_RS11540 4ee71ac721ef5cb739811a297d82f7ef 421 Pfam PF01420 Type I restriction modification DNA specificity domain 253 391 2.5E-4 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TOLA_RS11540 4ee71ac721ef5cb739811a297d82f7ef 421 PANTHER PTHR30408:SF6 157 418 1.5E-35 T 22-04-2016 TOLA_RS08195 14754fc04b7def2a5781dc6c4239006c 585 PANTHER PTHR11070 6 302 2.1E-30 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS08195 14754fc04b7def2a5781dc6c4239006c 585 Gene3D G3DSA:3.40.50.300 194 292 1.2E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08195 14754fc04b7def2a5781dc6c4239006c 585 Gene3D G3DSA:3.40.50.300 4 109 1.2E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08195 14754fc04b7def2a5781dc6c4239006c 585 SUPERFAMILY SSF52540 4 563 9.86E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08195 14754fc04b7def2a5781dc6c4239006c 585 Pfam PF00580 UvrD/REP helicase N-terminal domain 176 274 2.4E-15 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TOLA_RS08195 14754fc04b7def2a5781dc6c4239006c 585 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 73 3.8E-9 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TOLA_RS08195 14754fc04b7def2a5781dc6c4239006c 585 Gene3D G3DSA:3.40.50.300 504 569 4.1E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08195 14754fc04b7def2a5781dc6c4239006c 585 Gene3D G3DSA:3.40.50.300 293 387 4.1E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07990 db518b703f77c8a2718d5df609497131 288 Pfam PF01039 Carboxyl transferase domain 96 238 7.3E-16 T 22-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS07990 db518b703f77c8a2718d5df609497131 288 SUPERFAMILY SSF52096 23 281 7.96E-86 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS07990 db518b703f77c8a2718d5df609497131 288 Gene3D G3DSA:3.90.226.10 17 278 2.4E-72 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS07990 db518b703f77c8a2718d5df609497131 288 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 280 4.2E-137 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS07990 db518b703f77c8a2718d5df609497131 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 161 179 3.4E-39 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS07990 db518b703f77c8a2718d5df609497131 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 249 258 3.4E-39 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS07990 db518b703f77c8a2718d5df609497131 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 127 141 3.4E-39 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS07990 db518b703f77c8a2718d5df609497131 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 227 238 3.4E-39 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS07990 db518b703f77c8a2718d5df609497131 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 198 215 3.4E-39 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS07990 db518b703f77c8a2718d5df609497131 288 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 279 37.435 T 22-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS07990 db518b703f77c8a2718d5df609497131 288 PANTHER PTHR22855:SF17 1 281 1.1E-168 T 22-04-2016 TOLA_RS07990 db518b703f77c8a2718d5df609497131 288 PANTHER PTHR22855 1 281 1.1E-168 T 22-04-2016 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 SUPERFAMILY SSF46894 229 295 2.31E-18 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 269 281 8.5E-11 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 239 253 8.5E-11 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 253 269 8.5E-11 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 SMART SM00421 236 293 3.7E-17 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 Gene3D G3DSA:3.40.50.2300 9 131 2.0E-37 T 22-04-2016 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 Gene3D G3DSA:3.40.50.2300 224 244 2.0E-37 T 22-04-2016 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 PANTHER PTHR26402 9 137 1.6E-54 T 22-04-2016 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 PANTHER PTHR26402 235 295 1.6E-54 T 22-04-2016 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 Pfam PF00072 Response regulator receiver domain 11 120 1.8E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 Pfam PF00196 Bacterial regulatory proteins, luxR family 238 291 2.0E-19 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 SMART SM00448 9 120 5.8E-38 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 SUPERFAMILY SSF52172 7 136 1.39E-38 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS08295 86e61cab61a3ba7b5a30297527b6c52c 298 Gene3D G3DSA:1.10.10.10 245 295 7.0E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00970 02bbdd401f6eca40347c852f964d7ebe 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 20.409 T 22-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00970 02bbdd401f6eca40347c852f964d7ebe 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 8.0E-26 T 22-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00970 02bbdd401f6eca40347c852f964d7ebe 78 SUPERFAMILY SSF143800 1 77 2.55E-28 T 22-04-2016 TOLA_RS00970 02bbdd401f6eca40347c852f964d7ebe 78 PANTHER PTHR13528 1 74 9.5E-33 T 22-04-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 TOLA_RS00970 02bbdd401f6eca40347c852f964d7ebe 78 Gene3D G3DSA:2.30.170.40 2 78 8.6E-34 T 22-04-2016 TOLA_RS00970 02bbdd401f6eca40347c852f964d7ebe 78 Pfam PF00830 Ribosomal L28 family 3 61 1.5E-24 T 22-04-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 TOLA_RS06070 1c9027122c18e1173c58362d450cd0b7 372 Pfam PF08797 HIRAN domain 289 340 9.8E-8 T 22-04-2016 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 SUPERFAMILY SSF53067 101 309 5.9E-45 T 22-04-2016 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 Pfam PF00814 Glycoprotease family 24 307 1.7E-102 T 22-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 PANTHER PTHR11735 1 334 4.1E-167 T 22-04-2016 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 331 63.533 T 22-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 313 2.0E-136 T 22-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 306 1.2E-126 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 SUPERFAMILY SSF53067 3 122 5.61E-31 T 22-04-2016 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 1.7E-53 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 1.7E-53 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 1.7E-53 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.7E-53 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 1.7E-53 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 263 272 1.7E-53 T 22-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 PANTHER PTHR11735:SF6 1 334 4.1E-167 T 22-04-2016 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 Gene3D G3DSA:3.30.420.40 1 159 3.6E-48 T 22-04-2016 TOLA_RS13575 30986691c07f83a901ef10bd463d46b6 339 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 22-04-2016 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TOLA_RS12900 c6d7e33210073754053801febb1b6e49 99 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 62 79 9.7E-12 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS12900 c6d7e33210073754053801febb1b6e49 99 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 79 99 9.7E-12 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS12900 c6d7e33210073754053801febb1b6e49 99 SUPERFAMILY SSF46689 12 99 6.45E-24 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS12900 c6d7e33210073754053801febb1b6e49 99 Pfam PF02954 Bacterial regulatory protein, Fis family 56 96 7.2E-13 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS12900 c6d7e33210073754053801febb1b6e49 99 PANTHER PTHR32071 22 99 2.3E-28 T 22-04-2016 TOLA_RS12900 c6d7e33210073754053801febb1b6e49 99 Hamap MF_00166 DNA-binding protein Fis [fis]. 1 99 28.899 T 22-04-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 TOLA_RS12900 c6d7e33210073754053801febb1b6e49 99 PRINTS PR01591 DNA-binding protein FIS signature 9 26 1.1E-10 T 22-04-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 TOLA_RS12900 c6d7e33210073754053801febb1b6e49 99 PRINTS PR01591 DNA-binding protein FIS signature 43 58 1.1E-10 T 22-04-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 TOLA_RS12900 c6d7e33210073754053801febb1b6e49 99 PRINTS PR01591 DNA-binding protein FIS signature 58 70 1.1E-10 T 22-04-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 TOLA_RS12900 c6d7e33210073754053801febb1b6e49 99 PIRSF PIRSF002097 1 99 2.6E-42 T 22-04-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 TOLA_RS12900 c6d7e33210073754053801febb1b6e49 99 Gene3D G3DSA:1.10.10.60 28 99 7.9E-27 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 TIGRFAM TIGR00746 arcC: carbamate kinase 3 300 3.4E-112 T 22-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 PIRSF PIRSF000723 1 301 1.8E-105 T 22-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 Gene3D G3DSA:3.40.1160.10 2 299 1.8E-89 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 PRINTS PR01469 Bacterial carbamate kinase signature 42 61 1.0E-64 T 22-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 PRINTS PR01469 Bacterial carbamate kinase signature 206 221 1.0E-64 T 22-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 PRINTS PR01469 Bacterial carbamate kinase signature 175 193 1.0E-64 T 22-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 PRINTS PR01469 Bacterial carbamate kinase signature 104 123 1.0E-64 T 22-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 PRINTS PR01469 Bacterial carbamate kinase signature 257 272 1.0E-64 T 22-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 PRINTS PR01469 Bacterial carbamate kinase signature 152 171 1.0E-64 T 22-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 PRINTS PR01469 Bacterial carbamate kinase signature 72 90 1.0E-64 T 22-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 SUPERFAMILY SSF53633 1 299 1.48E-72 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 PANTHER PTHR30409:SF1 1 302 2.9E-135 T 22-04-2016 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 PANTHER PTHR30409 1 302 2.9E-135 T 22-04-2016 TOLA_RS12500 e6653137b3dd00d92950244a23ba1ada 302 Pfam PF00696 Amino acid kinase family 1 276 2.8E-30 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 6 405 1.1E-95 T 22-04-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 PANTHER PTHR11757 1 686 2.1E-303 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 Gene3D G3DSA:3.40.50.1820 419 660 8.8E-37 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 Gene3D G3DSA:2.130.10.120 76 409 1.0E-99 T 22-04-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 510 540 - T 22-04-2016 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 533 553 3.7E-48 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 449 467 3.7E-48 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 475 499 3.7E-48 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 609 631 3.7E-48 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 591 606 3.7E-48 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 503 522 3.7E-48 T 22-04-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 SUPERFAMILY SSF53474 417 658 2.56E-44 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 SUPERFAMILY SSF50993 3 412 1.44E-83 T 22-04-2016 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 Pfam PF00326 Prolyl oligopeptidase family 465 678 6.8E-64 T 22-04-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TOLA_RS00435 08fc0156d23e50285e2f083dc906b9b4 688 PANTHER PTHR11757:SF3 1 686 2.1E-303 T 22-04-2016 TOLA_RS13675 3692103843fa57935f40017c987adbac 397 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 392 55.539 T 22-04-2016 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 TOLA_RS13675 3692103843fa57935f40017c987adbac 397 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 82 317 2.8E-112 T 22-04-2016 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 TOLA_RS13675 3692103843fa57935f40017c987adbac 397 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2 80 2.0E-37 T 22-04-2016 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 TOLA_RS13675 3692103843fa57935f40017c987adbac 397 Pfam PF07055 Enoyl reductase FAD binding domain 323 386 2.2E-31 T 22-04-2016 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 TOLA_RS13675 3692103843fa57935f40017c987adbac 397 PANTHER PTHR37480 2 397 1.1E-236 T 22-04-2016 TOLA_RS10450 5f3b06f3e1a6e316fe1ebff28fa3e220 337 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 334 9.8E-140 T 22-04-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|UniPathway: UPA00214 TOLA_RS10450 5f3b06f3e1a6e316fe1ebff28fa3e220 337 PANTHER PTHR10366:SF39 2 336 1.9E-155 T 22-04-2016 TOLA_RS10450 5f3b06f3e1a6e316fe1ebff28fa3e220 337 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 324 1.2E-57 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10450 5f3b06f3e1a6e316fe1ebff28fa3e220 337 Gene3D G3DSA:3.40.50.720 1 178 1.3E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10450 5f3b06f3e1a6e316fe1ebff28fa3e220 337 SUPERFAMILY SSF51735 1 336 5.14E-94 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10450 5f3b06f3e1a6e316fe1ebff28fa3e220 337 Gene3D G3DSA:3.90.25.10 263 336 1.7E-52 T 22-04-2016 TOLA_RS10450 5f3b06f3e1a6e316fe1ebff28fa3e220 337 Gene3D G3DSA:3.90.25.10 179 231 1.7E-52 T 22-04-2016 TOLA_RS10450 5f3b06f3e1a6e316fe1ebff28fa3e220 337 PANTHER PTHR10366 2 336 1.9E-155 T 22-04-2016 TOLA_RS08930 e7afa3de629a5c4b26828382aff8fe66 159 PANTHER PTHR22960 3 159 1.5E-102 T 22-04-2016 TOLA_RS08930 e7afa3de629a5c4b26828382aff8fe66 159 Gene3D G3DSA:3.30.70.640 5 158 2.1E-69 T 22-04-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 TOLA_RS08930 e7afa3de629a5c4b26828382aff8fe66 159 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 4 159 35.634 T 22-04-2016 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type UniPathway: UPA00344 TOLA_RS08930 e7afa3de629a5c4b26828382aff8fe66 159 Pfam PF01967 MoaC family 17 152 1.6E-54 T 22-04-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 TOLA_RS08930 e7afa3de629a5c4b26828382aff8fe66 159 SUPERFAMILY SSF55040 13 157 1.96E-61 T 22-04-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 TOLA_RS08930 e7afa3de629a5c4b26828382aff8fe66 159 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 6 154 1.2E-68 T 22-04-2016 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 UniPathway: UPA00344 TOLA_RS01930 84408f65fee8786f6a941b2afba8319d 500 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 321 335 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 TOLA_RS01930 84408f65fee8786f6a941b2afba8319d 500 PANTHER PTHR30258:SF9 9 500 1.5E-293 T 22-04-2016 TOLA_RS01930 84408f65fee8786f6a941b2afba8319d 500 SUPERFAMILY SSF52540 108 497 1.21E-102 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01930 84408f65fee8786f6a941b2afba8319d 500 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 17 497 7.2E-214 T 22-04-2016 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 TOLA_RS01930 84408f65fee8786f6a941b2afba8319d 500 SUPERFAMILY SSF160246 16 80 7.32E-16 T 22-04-2016 TOLA_RS01930 84408f65fee8786f6a941b2afba8319d 500 Gene3D G3DSA:3.30.450.90 98 226 1.8E-53 T 22-04-2016 TOLA_RS01930 84408f65fee8786f6a941b2afba8319d 500 Gene3D G3DSA:3.40.50.300 232 498 6.7E-98 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01930 84408f65fee8786f6a941b2afba8319d 500 Pfam PF00437 Type II/IV secretion system protein 127 393 5.1E-90 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 TOLA_RS01930 84408f65fee8786f6a941b2afba8319d 500 PANTHER PTHR30258 9 500 1.5E-293 T 22-04-2016 TOLA_RS01930 84408f65fee8786f6a941b2afba8319d 500 SMART SM00382 254 377 9.5E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS05735 f4997eec60a66698c919acd891b09ef9 216 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 34 215 31.411 T 22-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 TOLA_RS05735 f4997eec60a66698c919acd891b09ef9 216 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 38 214 2.7E-79 T 22-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 TOLA_RS05735 f4997eec60a66698c919acd891b09ef9 216 SUPERFAMILY SSF55620 5 214 2.67E-72 T 22-04-2016 TOLA_RS05735 f4997eec60a66698c919acd891b09ef9 216 Gene3D G3DSA:3.30.1130.10 90 214 1.1E-48 T 22-04-2016 TOLA_RS05735 f4997eec60a66698c919acd891b09ef9 216 Pfam PF01227 GTP cyclohydrolase I 38 214 4.4E-61 T 22-04-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 TOLA_RS05735 f4997eec60a66698c919acd891b09ef9 216 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 144 154 - T 22-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 TOLA_RS05735 f4997eec60a66698c919acd891b09ef9 216 PANTHER PTHR11109 1 214 5.6E-95 T 22-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 TOLA_RS05735 f4997eec60a66698c919acd891b09ef9 216 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 96 112 - T 22-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 TOLA_RS05735 f4997eec60a66698c919acd891b09ef9 216 Gene3D G3DSA:1.10.286.10 4 84 4.7E-30 T 22-04-2016 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 PANTHER PTHR11540 1 311 1.7E-81 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 145 307 1.6E-17 T 22-04-2016 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 PANTHER PTHR11540:SF3 1 311 1.7E-81 T 22-04-2016 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 SUPERFAMILY SSF51735 3 144 2.18E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 SUPERFAMILY SSF56327 143 306 2.98E-37 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 Gene3D G3DSA:3.40.50.720 2 143 1.5E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 172 178 - T 22-04-2016 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|UniPathway: UPA00554 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 PRINTS PR00086 L-lactate dehydrogenase signature 5 29 2.3E-29 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 PRINTS PR00086 L-lactate dehydrogenase signature 30 54 2.3E-29 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 PRINTS PR00086 L-lactate dehydrogenase signature 116 136 2.3E-29 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 PRINTS PR00086 L-lactate dehydrogenase signature 140 158 2.3E-29 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 PRINTS PR00086 L-lactate dehydrogenase signature 170 183 2.3E-29 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 142 3.0E-28 T 22-04-2016 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 Gene3D G3DSA:3.90.110.10 144 309 1.4E-39 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TOLA_RS08895 09f023305aa5a685b42251ab6e2f099e 311 PIRSF PIRSF000102 1 310 2.1E-77 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TOLA_RS09945 c32ba80df0d55e0f3bd8cbdbbb908985 413 Gene3D G3DSA:3.90.1150.10 285 394 8.3E-35 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS09945 c32ba80df0d55e0f3bd8cbdbbb908985 413 Pfam PF00266 Aminotransferase class-V 17 360 6.0E-24 T 22-04-2016 IPR000192 Aminotransferase class V domain TOLA_RS09945 c32ba80df0d55e0f3bd8cbdbbb908985 413 SUPERFAMILY SSF53383 8 392 3.8E-92 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS09945 c32ba80df0d55e0f3bd8cbdbbb908985 413 Gene3D G3DSA:3.40.640.10 26 284 1.6E-61 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS09945 c32ba80df0d55e0f3bd8cbdbbb908985 413 PANTHER PTHR21152 244 410 1.6E-91 T 22-04-2016 TOLA_RS09945 c32ba80df0d55e0f3bd8cbdbbb908985 413 PANTHER PTHR21152 10 228 1.6E-91 T 22-04-2016 TOLA_RS09945 c32ba80df0d55e0f3bd8cbdbbb908985 413 PIRSF PIRSF000524 9 412 1.5E-106 T 22-04-2016 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 TOLA_RS03155 fa3c1fe4c0dcb3b0adc7641d0a15da54 164 SUPERFAMILY SSF55021 79 161 1.27E-25 T 22-04-2016 TOLA_RS03155 fa3c1fe4c0dcb3b0adc7641d0a15da54 164 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 6.0E-30 T 22-04-2016 TOLA_RS03155 fa3c1fe4c0dcb3b0adc7641d0a15da54 164 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 159 2.0E-63 T 22-04-2016 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS03155 fa3c1fe4c0dcb3b0adc7641d0a15da54 164 Gene3D G3DSA:3.30.70.260 1 78 5.8E-36 T 22-04-2016 TOLA_RS03155 fa3c1fe4c0dcb3b0adc7641d0a15da54 164 SUPERFAMILY SSF55021 2 76 2.98E-21 T 22-04-2016 TOLA_RS03155 fa3c1fe4c0dcb3b0adc7641d0a15da54 164 PANTHER PTHR30239 1 164 5.7E-89 T 22-04-2016 TOLA_RS03155 fa3c1fe4c0dcb3b0adc7641d0a15da54 164 Pfam PF10369 Small subunit of acetolactate synthase 84 158 3.6E-24 T 22-04-2016 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS03155 fa3c1fe4c0dcb3b0adc7641d0a15da54 164 Pfam PF13710 ACT domain 13 73 3.4E-14 T 22-04-2016 TOLA_RS03155 fa3c1fe4c0dcb3b0adc7641d0a15da54 164 Gene3D G3DSA:3.30.70.1150 83 162 2.5E-26 T 22-04-2016 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 SUPERFAMILY SSF50447 584 665 1.37E-23 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 Gene3D G3DSA:2.40.30.10 812 908 5.7E-40 T 22-04-2016 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 Gene3D G3DSA:3.40.50.10050 710 789 1.3E-25 T 22-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 SUPERFAMILY SSF52540 408 575 2.85E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 Gene3D G3DSA:3.30.56.50 2 50 5.9E-21 T 22-04-2016 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 SUPERFAMILY SSF46955 3 50 3.3E-12 T 22-04-2016 IPR009061 Putative DNA-binding domain TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 327 910 7.0E-289 T 22-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 335 385 4.8E-15 T 22-04-2016 IPR006847 Translation initiation factor IF-2, N-terminal TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 50 8.8E-7 T 22-04-2016 IPR006847 Translation initiation factor IF-2, N-terminal TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 PANTHER PTHR23115 763 908 1.0E-211 T 22-04-2016 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 PANTHER PTHR23115 388 738 1.0E-211 T 22-04-2016 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 Pfam PF11987 Translation-initiation factor 2 695 799 6.2E-38 T 22-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 ProSitePatterns PS01176 Initiation factor 2 signature. 861 883 - T 22-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 60 98 1.5E-13 T 22-04-2016 IPR013575 Initiation factor 2 associated domain, bacterial TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 SUPERFAMILY SSF52156 688 817 8.11E-39 T 22-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 SUPERFAMILY SSF50447 811 908 6.87E-35 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 Gene3D G3DSA:3.40.50.300 402 569 3.3E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 Pfam PF00009 Elongation factor Tu GTP binding domain 415 570 2.5E-34 T 22-04-2016 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 Gene3D G3DSA:2.40.30.10 584 674 9.3E-22 T 22-04-2016 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 908 17.64 T 22-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 413 569 4.9E-34 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 PANTHER PTHR23115:SF184 763 908 1.0E-211 T 22-04-2016 TOLA_RS11400 1eb049ff5899e067a0db11d001d5d128 910 PANTHER PTHR23115:SF184 388 738 1.0E-211 T 22-04-2016 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Gene3D G3DSA:1.10.1030.10 400 538 9.5E-52 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Gene3D G3DSA:3.40.50.20 539 662 2.6E-61 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Gene3D G3DSA:3.30.1490.20 686 744 3.2E-25 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 PANTHER PTHR11405:SF5 1 1068 0.0 T 22-04-2016 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Pfam PF02142 MGS-like domain 956 1041 3.8E-16 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Gene3D G3DSA:3.30.470.20 201 399 6.7E-76 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Gene3D G3DSA:3.30.470.20 745 933 1.7E-78 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 SUPERFAMILY SSF52335 936 1071 3.27E-33 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 SUPERFAMILY SSF52440 556 675 3.45E-49 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 SMART SM01096 424 547 6.4E-75 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 673 875 1.9E-35 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 4.1E-72 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 PANTHER PTHR11405 1 1068 0.0 T 22-04-2016 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Gene3D G3DSA:3.40.50.20 4 108 6.6E-46 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Gene3D G3DSA:3.30.1490.20 141 200 1.4E-25 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 547 3.4E-40 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1062 13.088 T 22-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 SMART SM00851 955 1041 1.5E-28 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1047 0.0 T 22-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 SUPERFAMILY SSF56059 128 401 6.54E-109 T 22-04-2016 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1067 13.335 T 22-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 SUPERFAMILY SSF56059 673 933 1.56E-101 T 22-04-2016 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 Gene3D G3DSA:3.40.50.1380 938 1071 9.7E-37 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 SUPERFAMILY SSF52440 1 127 3.31E-50 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 SUPERFAMILY SSF48108 396 554 7.45E-54 T 22-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 709 723 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 4.5E-66 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 4.5E-66 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 4.5E-66 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 4.5E-66 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 4.5E-66 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 4.5E-66 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05285 8440eb4295bdcfe4545e8c4eb6e59179 1075 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 4.5E-66 T 22-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 PANTHER PTHR10174:SF116 202 371 1.3E-144 T 22-04-2016 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 PANTHER PTHR10174:SF116 104 180 1.3E-144 T 22-04-2016 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 Gene3D G3DSA:3.30.360.10 144 352 1.1E-73 T 22-04-2016 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 SUPERFAMILY SSF55347 135 356 1.37E-75 T 22-04-2016 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 369 33.721 T 22-04-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 145 355 1.1E-54 T 22-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 263 277 - T 22-04-2016 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 PIRSF PIRSF000148 1 372 5.9E-69 T 22-04-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 2 369 2.3E-198 T 22-04-2016 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 SUPERFAMILY SSF51735 1 148 1.31E-54 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 123 1.3E-23 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 PANTHER PTHR10174 202 371 1.3E-144 T 22-04-2016 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 PANTHER PTHR10174 104 180 1.3E-144 T 22-04-2016 TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 Gene3D G3DSA:3.40.50.720 1 143 1.5E-61 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04535 e5ba0ef63a6c117adadcf8e6660f95c9 372 SMART SM00859 3 123 8.3E-27 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TOLA_RS13010 860245f8176420ad35aadff476f0b88e 344 Pfam PF00005 ABC transporter 19 165 1.3E-36 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS13010 860245f8176420ad35aadff476f0b88e 344 SUPERFAMILY SSF52540 4 245 4.64E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13010 860245f8176420ad35aadff476f0b88e 344 PANTHER PTHR24220 5 252 3.1E-113 T 22-04-2016 TOLA_RS13010 860245f8176420ad35aadff476f0b88e 344 PANTHER PTHR24220:SF282 5 252 3.1E-113 T 22-04-2016 TOLA_RS13010 860245f8176420ad35aadff476f0b88e 344 Gene3D G3DSA:3.40.50.300 2 238 2.0E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13010 860245f8176420ad35aadff476f0b88e 344 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS13010 860245f8176420ad35aadff476f0b88e 344 SMART SM00382 28 215 4.2E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS01860 34c09b53add6ca33f0b5459ce189d78d 463 Gene3D G3DSA:1.20.1600.10 48 85 9.7E-107 T 22-04-2016 TOLA_RS01860 34c09b53add6ca33f0b5459ce189d78d 463 Gene3D G3DSA:1.20.1600.10 346 460 9.7E-107 T 22-04-2016 TOLA_RS01860 34c09b53add6ca33f0b5459ce189d78d 463 Gene3D G3DSA:1.20.1600.10 136 308 9.7E-107 T 22-04-2016 TOLA_RS01860 34c09b53add6ca33f0b5459ce189d78d 463 Pfam PF02321 Outer membrane efflux protein 276 457 7.1E-29 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS01860 34c09b53add6ca33f0b5459ce189d78d 463 Pfam PF02321 Outer membrane efflux protein 59 248 1.1E-30 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS01860 34c09b53add6ca33f0b5459ce189d78d 463 Gene3D G3DSA:2.20.200.10 309 344 8.9E-21 T 22-04-2016 TOLA_RS01860 34c09b53add6ca33f0b5459ce189d78d 463 Gene3D G3DSA:2.20.200.10 95 135 8.9E-21 T 22-04-2016 TOLA_RS01860 34c09b53add6ca33f0b5459ce189d78d 463 PANTHER PTHR30203:SF15 1 461 1.7E-163 T 22-04-2016 TOLA_RS01860 34c09b53add6ca33f0b5459ce189d78d 463 PANTHER PTHR30203 1 461 1.7E-163 T 22-04-2016 TOLA_RS01860 34c09b53add6ca33f0b5459ce189d78d 463 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 459 1.9E-133 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 TOLA_RS01860 34c09b53add6ca33f0b5459ce189d78d 463 SUPERFAMILY SSF56954 2 461 3.4E-118 T 22-04-2016 TOLA_RS11355 6ad719dda664a0137c715a408698c9d5 200 Pfam PF09335 SNARE associated Golgi protein 29 156 6.8E-22 T 22-04-2016 IPR032816 SNARE associated Golgi protein TOLA_RS11355 6ad719dda664a0137c715a408698c9d5 200 PANTHER PTHR30353 1 196 2.2E-50 T 22-04-2016 IPR032818 DedA family TOLA_RS11355 6ad719dda664a0137c715a408698c9d5 200 PANTHER PTHR30353:SF1 1 196 2.2E-50 T 22-04-2016 TOLA_RS07090 7a6ba327044f164c5a74f7a7b05c1c1c 376 Pfam PF10442 FIST C domain 212 349 3.3E-18 T 22-04-2016 IPR019494 FIST, C-domain TOLA_RS07090 7a6ba327044f164c5a74f7a7b05c1c1c 376 SMART SM01204 212 351 7.0E-27 T 22-04-2016 IPR019494 FIST, C-domain TOLA_RS07090 7a6ba327044f164c5a74f7a7b05c1c1c 376 Pfam PF08495 FIST N domain 52 210 4.6E-17 T 22-04-2016 IPR013702 FIST domain, N-terminal TOLA_RS07090 7a6ba327044f164c5a74f7a7b05c1c1c 376 PANTHER PTHR40252 116 376 6.7E-14 T 22-04-2016 TOLA_RS07090 7a6ba327044f164c5a74f7a7b05c1c1c 376 SMART SM00897 27 211 1.2E-11 T 22-04-2016 IPR013702 FIST domain, N-terminal TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 SUPERFAMILY SSF52540 145 387 3.52E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 Gene3D G3DSA:3.40.50.300 145 317 2.0E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 Gene3D G3DSA:1.10.10.60 400 450 1.7E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 PANTHER PTHR32071 102 450 3.7E-144 T 22-04-2016 TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 Pfam PF02954 Bacterial regulatory protein, Fis family 409 448 1.6E-7 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 SMART SM00382 165 308 4.8E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 Gene3D G3DSA:1.10.8.60 318 390 1.1E-23 T 22-04-2016 TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 SUPERFAMILY SSF46689 358 450 2.69E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 414 431 8.3E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 431 451 8.3E-5 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 Pfam PF00158 Sigma-54 interaction domain 145 311 1.9E-67 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TOLA_RS04905 f5c16e535153e9090bf782c6ad0d9adb 453 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TOLA_RS15305 f79f645d4d73acffe4e9d368938b352f 101 PANTHER PTHR34581:SF2 2 100 7.5E-41 T 22-04-2016 TOLA_RS15305 f79f645d4d73acffe4e9d368938b352f 101 Gene3D G3DSA:3.40.50.270 1 100 2.1E-38 T 22-04-2016 TOLA_RS15305 f79f645d4d73acffe4e9d368938b352f 101 SUPERFAMILY SSF52794 1 100 9.42E-36 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS15305 f79f645d4d73acffe4e9d368938b352f 101 PANTHER PTHR34581 2 100 7.5E-41 T 22-04-2016 TOLA_RS15305 f79f645d4d73acffe4e9d368938b352f 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 1.6E-24 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS13335 d3c14a3039914e79986080c49afc8f4d 360 SUPERFAMILY SSF53067 18 184 2.16E-7 T 22-04-2016 TOLA_RS13335 d3c14a3039914e79986080c49afc8f4d 360 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 17 355 2.7E-73 T 22-04-2016 IPR005883 Type IV pilus assembly protein PilM TOLA_RS13335 d3c14a3039914e79986080c49afc8f4d 360 PIRSF PIRSF019169 4 356 1.8E-83 T 22-04-2016 IPR005883 Type IV pilus assembly protein PilM TOLA_RS13335 d3c14a3039914e79986080c49afc8f4d 360 Gene3D G3DSA:3.30.420.40 201 321 2.1E-19 T 22-04-2016 TOLA_RS13335 d3c14a3039914e79986080c49afc8f4d 360 PANTHER PTHR32432:SF3 5 360 3.6E-64 T 22-04-2016 TOLA_RS13335 d3c14a3039914e79986080c49afc8f4d 360 SUPERFAMILY SSF53067 196 355 6.48E-18 T 22-04-2016 TOLA_RS13335 d3c14a3039914e79986080c49afc8f4d 360 PANTHER PTHR32432 5 360 3.6E-64 T 22-04-2016 TOLA_RS13335 d3c14a3039914e79986080c49afc8f4d 360 Gene3D G3DSA:3.30.420.40 14 106 3.8E-6 T 22-04-2016 TOLA_RS13335 d3c14a3039914e79986080c49afc8f4d 360 Pfam PF11104 Type IV pilus assembly protein PilM; 19 355 4.2E-88 T 22-04-2016 IPR005883 Type IV pilus assembly protein PilM TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 SUPERFAMILY SSF53067 10 258 1.76E-96 T 22-04-2016 TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 140 152 - T 22-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 264 453 7.5E-61 T 22-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 PANTHER PTHR10196 1 501 1.3E-264 T 22-04-2016 TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 Gene3D G3DSA:3.30.420.40 258 500 5.8E-102 T 22-04-2016 TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 10 255 5.4E-88 T 22-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 SUPERFAMILY SSF53067 258 500 8.03E-86 T 22-04-2016 TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 PIRSF PIRSF000538 8 501 6.7E-180 T 22-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 10 499 2.7E-228 T 22-04-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 Gene3D G3DSA:3.30.420.40 5 256 3.5E-108 T 22-04-2016 TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 22-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 Hamap MF_00186 Glycerol kinase [glpK]. 8 500 59.771 T 22-04-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 TOLA_RS00370 7be5fa6bfe4e958b436a1eb30437880f 501 PANTHER PTHR10196:SF9 1 501 1.3E-264 T 22-04-2016 TOLA_RS14610 3bac7e1914c78dfa0bd15193c2ffe255 96 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 86 4.9E-10 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TOLA_RS14610 3bac7e1914c78dfa0bd15193c2ffe255 96 PANTHER PTHR35601 1 95 2.3E-44 T 22-04-2016 TOLA_RS14610 3bac7e1914c78dfa0bd15193c2ffe255 96 PANTHER PTHR35601:SF2 1 95 2.3E-44 T 22-04-2016 TOLA_RS14610 3bac7e1914c78dfa0bd15193c2ffe255 96 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 83 7.5E-13 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TOLA_RS14610 3bac7e1914c78dfa0bd15193c2ffe255 96 SUPERFAMILY SSF143011 1 82 1.14E-22 T 22-04-2016 TOLA_RS04040 140991f86bc9ab687ebbf1916ce5932e 296 SUPERFAMILY SSF53850 89 294 6.95E-45 T 22-04-2016 TOLA_RS04040 140991f86bc9ab687ebbf1916ce5932e 296 Pfam PF03466 LysR substrate binding domain 88 286 6.0E-48 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS04040 140991f86bc9ab687ebbf1916ce5932e 296 Gene3D G3DSA:3.40.190.10 91 173 1.8E-19 T 22-04-2016 TOLA_RS04040 140991f86bc9ab687ebbf1916ce5932e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 7.5E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS04040 140991f86bc9ab687ebbf1916ce5932e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 7.5E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS04040 140991f86bc9ab687ebbf1916ce5932e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 7.5E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS04040 140991f86bc9ab687ebbf1916ce5932e 296 Gene3D G3DSA:3.40.190.10 174 258 1.2E-19 T 22-04-2016 TOLA_RS04040 140991f86bc9ab687ebbf1916ce5932e 296 Gene3D G3DSA:1.10.10.10 1 82 5.7E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS04040 140991f86bc9ab687ebbf1916ce5932e 296 PANTHER PTHR30126 3 289 2.0E-135 T 22-04-2016 TOLA_RS04040 140991f86bc9ab687ebbf1916ce5932e 296 SUPERFAMILY SSF46785 3 109 5.39E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS04040 140991f86bc9ab687ebbf1916ce5932e 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 1.1E-17 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS04040 140991f86bc9ab687ebbf1916ce5932e 296 PANTHER PTHR30126:SF36 3 289 2.0E-135 T 22-04-2016 TOLA_RS14375 369316bb53edeac2f8e0f304a8c8a398 154 SUPERFAMILY SSF57825 102 151 2.09E-14 T 22-04-2016 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal TOLA_RS14375 369316bb53edeac2f8e0f304a8c8a398 154 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 9 99 1.0E-32 T 22-04-2016 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal TOLA_RS14375 369316bb53edeac2f8e0f304a8c8a398 154 PANTHER PTHR35805 2 154 1.2E-67 T 22-04-2016 TOLA_RS14375 369316bb53edeac2f8e0f304a8c8a398 154 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 4 152 33.0 T 22-04-2016 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 TOLA_RS14375 369316bb53edeac2f8e0f304a8c8a398 154 PANTHER PTHR35805:SF1 2 154 1.2E-67 T 22-04-2016 TOLA_RS14375 369316bb53edeac2f8e0f304a8c8a398 154 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 5 150 1.9E-58 T 22-04-2016 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 TOLA_RS14375 369316bb53edeac2f8e0f304a8c8a398 154 SUPERFAMILY SSF54893 2 100 6.41E-35 T 22-04-2016 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal TOLA_RS14375 369316bb53edeac2f8e0f304a8c8a398 154 Gene3D G3DSA:2.30.30.20 102 151 3.9E-22 T 22-04-2016 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal TOLA_RS14375 369316bb53edeac2f8e0f304a8c8a398 154 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 7 97 4.4E-31 T 22-04-2016 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal TOLA_RS14375 369316bb53edeac2f8e0f304a8c8a398 154 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 102 150 7.0E-19 T 22-04-2016 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal TOLA_RS14375 369316bb53edeac2f8e0f304a8c8a398 154 Gene3D G3DSA:3.30.70.140 2 99 2.7E-36 T 22-04-2016 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 318 528 9.5E-49 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 Pfam PF02824 TGS domain 4 61 3.0E-12 T 22-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 631 7.2E-243 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 SUPERFAMILY SSF81271 3 61 3.92E-16 T 22-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 172 219 9.5E-14 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 634 33.938 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 Gene3D G3DSA:3.30.54.20 130 187 4.1E-20 T 22-04-2016 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 SUPERFAMILY SSF55186 63 241 8.11E-64 T 22-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 PANTHER PTHR11451 1 642 0.0 T 22-04-2016 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 PANTHER PTHR11451:SF31 1 642 0.0 T 22-04-2016 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 SUPERFAMILY SSF52954 530 635 1.04E-30 T 22-04-2016 IPR004154 Anticodon-binding TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 Gene3D G3DSA:3.10.20.30 1 64 6.0E-24 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 Pfam PF03129 Anticodon binding domain 541 630 2.0E-19 T 22-04-2016 IPR004154 Anticodon-binding TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 Gene3D G3DSA:3.40.50.800 532 638 1.1E-34 T 22-04-2016 IPR004154 Anticodon-binding TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 362 385 2.7E-54 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 329 357 2.7E-54 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 464 492 2.7E-54 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 534 546 2.7E-54 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 PRINTS PR01047 Threonyl-tRNA synthetase signature 507 520 2.7E-54 T 22-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 SMART SM00863 170 219 6.7E-19 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 SUPERFAMILY SSF55681 243 525 4.21E-98 T 22-04-2016 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 Gene3D G3DSA:3.30.980.10 188 224 1.6E-39 T 22-04-2016 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 Gene3D G3DSA:3.30.980.10 66 129 1.6E-39 T 22-04-2016 TOLA_RS08795 374ec09fe1afb04e8ac1cf02de4e0453 642 Gene3D G3DSA:3.30.930.10 242 528 5.1E-120 T 22-04-2016 TOLA_RS15155 fdd0e3c60fd0f6a520e20714273e1fc3 317 PIRSF PIRSF004491 1 310 1.7E-106 T 22-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 TOLA_RS15155 fdd0e3c60fd0f6a520e20714273e1fc3 317 Pfam PF06574 FAD synthetase 13 166 6.4E-56 T 22-04-2016 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 TOLA_RS15155 fdd0e3c60fd0f6a520e20714273e1fc3 317 SMART SM00904 183 306 4.0E-61 T 22-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 TOLA_RS15155 fdd0e3c60fd0f6a520e20714273e1fc3 317 SUPERFAMILY SSF52374 17 180 1.41E-33 T 22-04-2016 TOLA_RS15155 fdd0e3c60fd0f6a520e20714273e1fc3 317 SUPERFAMILY SSF82114 174 308 6.1E-46 T 22-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 TOLA_RS15155 fdd0e3c60fd0f6a520e20714273e1fc3 317 PANTHER PTHR22749:SF0 1 311 3.3E-135 T 22-04-2016 TOLA_RS15155 fdd0e3c60fd0f6a520e20714273e1fc3 317 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 305 3.3E-102 T 22-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 TOLA_RS15155 fdd0e3c60fd0f6a520e20714273e1fc3 317 Pfam PF01687 Riboflavin kinase 184 305 1.5E-38 T 22-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 TOLA_RS15155 fdd0e3c60fd0f6a520e20714273e1fc3 317 Gene3D G3DSA:3.40.50.620 1 179 7.3E-66 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS15155 fdd0e3c60fd0f6a520e20714273e1fc3 317 Gene3D G3DSA:2.40.30.30 180 309 9.1E-41 T 22-04-2016 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 TOLA_RS15155 fdd0e3c60fd0f6a520e20714273e1fc3 317 PANTHER PTHR22749 1 311 3.3E-135 T 22-04-2016 IPR023468 Riboflavin kinase KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|UniPathway: UPA00276 TOLA_RS09775 703e33ea72c0aff33629b9c6c8a4a64c 165 Gene3D G3DSA:2.40.100.10 1 163 1.6E-55 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS09775 703e33ea72c0aff33629b9c6c8a4a64c 165 PANTHER PTHR11071:SF192 4 165 8.6E-77 T 22-04-2016 TOLA_RS09775 703e33ea72c0aff33629b9c6c8a4a64c 165 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 37 54 - T 22-04-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 TOLA_RS09775 703e33ea72c0aff33629b9c6c8a4a64c 165 SUPERFAMILY SSF50891 3 163 2.63E-60 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS09775 703e33ea72c0aff33629b9c6c8a4a64c 165 PANTHER PTHR11071 4 165 8.6E-77 T 22-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 TOLA_RS09775 703e33ea72c0aff33629b9c6c8a4a64c 165 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 3 162 7.1E-48 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 TOLA_RS09775 703e33ea72c0aff33629b9c6c8a4a64c 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 16 31 6.7E-13 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 TOLA_RS09775 703e33ea72c0aff33629b9c6c8a4a64c 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 119 134 6.7E-13 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 TOLA_RS09775 703e33ea72c0aff33629b9c6c8a4a64c 165 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 42 54 6.7E-13 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 TOLA_RS09775 703e33ea72c0aff33629b9c6c8a4a64c 165 PIRSF PIRSF001467 1 165 6.4E-30 T 22-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 1.9E-18 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 SMART SM00354 4 74 2.7E-30 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 SUPERFAMILY SSF47413 3 61 9.85E-16 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 PANTHER PTHR30146:SF42 4 309 1.9E-158 T 22-04-2016 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 Gene3D G3DSA:1.10.260.40 6 56 7.0E-23 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 SUPERFAMILY SSF53822 63 305 2.16E-59 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 6 16 4.2E-5 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 16 26 4.2E-5 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 PANTHER PTHR30146 4 309 1.9E-158 T 22-04-2016 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 TIGRFAM TIGR02405 trehalos_R_Ecol: trehalose operon repressor 4 311 4.4E-133 T 22-04-2016 IPR012771 Trehalose operon repressor GO:0003677|GO:0005991|GO:0045892 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 Pfam PF13377 Periplasmic binding protein-like domain 168 305 1.2E-16 T 22-04-2016 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 Gene3D G3DSA:3.40.50.2300 57 174 2.5E-22 T 22-04-2016 TOLA_RS00890 433326fd12c1ccca53b8cf815eae719d 315 Gene3D G3DSA:3.40.50.2300 175 277 1.4E-35 T 22-04-2016 TOLA_RS06830 126d1e084255ce99e35ee04dbe19ba68 375 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS06830 126d1e084255ce99e35ee04dbe19ba68 375 SMART SM00382 28 211 8.5E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS06830 126d1e084255ce99e35ee04dbe19ba68 375 Gene3D G3DSA:2.40.50.100 239 284 1.7E-10 T 22-04-2016 TOLA_RS06830 126d1e084255ce99e35ee04dbe19ba68 375 Gene3D G3DSA:2.40.50.100 345 353 1.7E-10 T 22-04-2016 TOLA_RS06830 126d1e084255ce99e35ee04dbe19ba68 375 PANTHER PTHR24220 5 375 2.8E-163 T 22-04-2016 TOLA_RS06830 126d1e084255ce99e35ee04dbe19ba68 375 Gene3D G3DSA:3.40.50.300 4 234 7.2E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06830 126d1e084255ce99e35ee04dbe19ba68 375 Pfam PF08402 TOBE domain 280 351 2.7E-11 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 TOLA_RS06830 126d1e084255ce99e35ee04dbe19ba68 375 SUPERFAMILY SSF52540 4 242 2.43E-87 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06830 126d1e084255ce99e35ee04dbe19ba68 375 SUPERFAMILY SSF50331 236 355 4.37E-27 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS06830 126d1e084255ce99e35ee04dbe19ba68 375 Gene3D G3DSA:2.40.50.140 285 343 4.9E-15 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS06830 126d1e084255ce99e35ee04dbe19ba68 375 Pfam PF00005 ABC transporter 20 161 8.0E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS06830 126d1e084255ce99e35ee04dbe19ba68 375 PANTHER PTHR24220:SF572 5 375 2.8E-163 T 22-04-2016 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 SUPERFAMILY SSF103088 208 332 8.89E-31 T 22-04-2016 IPR006665 OmpA-like domain TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 Gene3D G3DSA:3.30.1330.60 206 332 6.5E-35 T 22-04-2016 IPR006665 OmpA-like domain TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 PRINTS PR01021 OMPA domain signature 221 243 2.8E-18 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 PRINTS PR01021 OMPA domain signature 253 268 2.8E-18 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 PRINTS PR01021 OMPA domain signature 268 284 2.8E-18 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 Pfam PF01389 OmpA-like transmembrane domain 31 185 4.9E-30 T 22-04-2016 IPR000498 Outer membrane protein OmpA-like, transmembrane domain GO:0009279|GO:0016021 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 PANTHER PTHR30128:SF16 1 341 5.5E-43 T 22-04-2016 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 SUPERFAMILY SSF56925 25 179 2.33E-21 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 PANTHER PTHR30128 1 341 5.5E-43 T 22-04-2016 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 PRINTS PR01022 Outer membrane protein A signature 209 224 1.5E-22 T 22-04-2016 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 PRINTS PR01022 Outer membrane protein A signature 311 324 1.5E-22 T 22-04-2016 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 PRINTS PR01022 Outer membrane protein A signature 238 257 1.5E-22 T 22-04-2016 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 PRINTS PR01022 Outer membrane protein A signature 277 296 1.5E-22 T 22-04-2016 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 PRINTS PR01022 Outer membrane protein A signature 103 119 1.5E-22 T 22-04-2016 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 Pfam PF00691 OmpA family 220 311 3.7E-21 T 22-04-2016 IPR006665 OmpA-like domain TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 ProSitePatterns PS01068 OmpA-like domain. 255 299 - T 22-04-2016 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 TOLA_RS05815 23194c9d5187c1e51580d53f86c4d2c8 341 Gene3D G3DSA:2.40.160.20 14 205 4.5E-38 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 TOLA_RS10330 24a20091f68e3eac350cb1016049d84d 213 Pfam PF00089 Trypsin 21 170 5.9E-24 T 22-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TOLA_RS10330 24a20091f68e3eac350cb1016049d84d 213 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 124 135 - T 22-04-2016 IPR033116 Serine proteases, trypsin family, serine active site TOLA_RS10330 24a20091f68e3eac350cb1016049d84d 213 SMART SM00020 2 170 6.1E-10 T 22-04-2016 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 TOLA_RS10330 24a20091f68e3eac350cb1016049d84d 213 Gene3D G3DSA:2.40.10.10 7 46 4.9E-6 T 22-04-2016 TOLA_RS10330 24a20091f68e3eac350cb1016049d84d 213 SUPERFAMILY SSF50494 4 174 1.89E-37 T 22-04-2016 IPR009003 Peptidase S1, PA clan TOLA_RS10330 24a20091f68e3eac350cb1016049d84d 213 PANTHER PTHR24260 25 178 7.0E-32 T 22-04-2016 TOLA_RS10330 24a20091f68e3eac350cb1016049d84d 213 Gene3D G3DSA:2.40.10.10 47 174 2.7E-26 T 22-04-2016 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 70 500 4.5E-120 T 22-04-2016 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 Gene3D G3DSA:3.40.50.1980 70 211 1.6E-51 T 22-04-2016 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 Gene3D G3DSA:3.40.50.1980 345 476 5.5E-55 T 22-04-2016 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 TIGRFAM TIGR01286 nifK: nitrogenase molybdenum-iron protein beta chain 2 522 1.2E-261 T 22-04-2016 IPR005976 Nitrogenase molybdenum-iron protein beta chain GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 PANTHER PTHR33712 29 255 9.7E-176 T 22-04-2016 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 PANTHER PTHR33712 273 510 9.7E-176 T 22-04-2016 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 88 95 - T 22-04-2016 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 151 165 - T 22-04-2016 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 Gene3D G3DSA:3.40.50.1980 218 319 1.6E-38 T 22-04-2016 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 PANTHER PTHR33712:SF7 29 255 9.7E-176 T 22-04-2016 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 PANTHER PTHR33712:SF7 273 510 9.7E-176 T 22-04-2016 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 SUPERFAMILY SSF53807 3 521 7.85E-171 T 22-04-2016 TOLA_RS03360 7a52070240cda90d8745a4c913ac8e93 522 Pfam PF11844 Domain of unknown function (DUF3364) 1 56 1.5E-23 T 22-04-2016 IPR024564 Nitrogenase molybdenum-iron protein beta chain, N-terminal KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 TOLA_RS14775 70a5d37c492b0223adc58b9c6c42aa35 393 Gene3D G3DSA:3.20.20.150 1 391 9.4E-154 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS14775 70a5d37c492b0223adc58b9c6c42aa35 393 Hamap MF_00106 Mannonate dehydratase [uxuA]. 1 393 226.496 T 22-04-2016 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242|UniPathway: UPA00246 TOLA_RS14775 70a5d37c492b0223adc58b9c6c42aa35 393 PANTHER PTHR30387:SF2 1 393 1.1E-180 T 22-04-2016 TOLA_RS14775 70a5d37c492b0223adc58b9c6c42aa35 393 PIRSF PIRSF016049 1 392 7.4E-182 T 22-04-2016 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242|UniPathway: UPA00246 TOLA_RS14775 70a5d37c492b0223adc58b9c6c42aa35 393 TIGRFAM TIGR00695 uxuA: mannonate dehydratase 1 392 1.1E-221 T 22-04-2016 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242|UniPathway: UPA00246 TOLA_RS14775 70a5d37c492b0223adc58b9c6c42aa35 393 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 388 7.0E-162 T 22-04-2016 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242|UniPathway: UPA00246 TOLA_RS14775 70a5d37c492b0223adc58b9c6c42aa35 393 SUPERFAMILY SSF51658 1 133 9.81E-80 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS14775 70a5d37c492b0223adc58b9c6c42aa35 393 SUPERFAMILY SSF51658 163 383 9.81E-80 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS14775 70a5d37c492b0223adc58b9c6c42aa35 393 PANTHER PTHR30387 1 393 1.1E-180 T 22-04-2016 TOLA_RS10090 218fd4569a486b11614782ac0b046765 242 PANTHER PTHR24220 5 242 1.3E-140 T 22-04-2016 TOLA_RS10090 218fd4569a486b11614782ac0b046765 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS10090 218fd4569a486b11614782ac0b046765 242 SMART SM00382 28 215 1.1E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS10090 218fd4569a486b11614782ac0b046765 242 Pfam PF00005 ABC transporter 19 167 1.9E-36 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS10090 218fd4569a486b11614782ac0b046765 242 Gene3D G3DSA:3.40.50.300 2 239 1.6E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10090 218fd4569a486b11614782ac0b046765 242 PANTHER PTHR24220:SF550 5 242 1.3E-140 T 22-04-2016 TOLA_RS10090 218fd4569a486b11614782ac0b046765 242 SUPERFAMILY SSF52540 3 237 3.1E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10090 218fd4569a486b11614782ac0b046765 242 PIRSF PIRSF039085 1 242 4.5E-111 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TOLA_RS04415 bc9c3191c4e5f364e818751de6dffac0 255 Pfam PF12697 Alpha/beta hydrolase family 12 243 3.1E-23 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS04415 bc9c3191c4e5f364e818751de6dffac0 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 78 91 4.9E-7 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS04415 bc9c3191c4e5f364e818751de6dffac0 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 35 50 4.9E-7 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS04415 bc9c3191c4e5f364e818751de6dffac0 255 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 4.9E-7 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS04415 bc9c3191c4e5f364e818751de6dffac0 255 PANTHER PTHR10992:SF768 11 253 8.0E-75 T 22-04-2016 TOLA_RS04415 bc9c3191c4e5f364e818751de6dffac0 255 PRINTS PR00412 Epoxide hydrolase signature 92 105 3.1E-5 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 TOLA_RS04415 bc9c3191c4e5f364e818751de6dffac0 255 PRINTS PR00412 Epoxide hydrolase signature 228 250 3.1E-5 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 TOLA_RS04415 bc9c3191c4e5f364e818751de6dffac0 255 PRINTS PR00412 Epoxide hydrolase signature 35 50 3.1E-5 T 22-04-2016 IPR000639 Epoxide hydrolase-like GO:0003824 TOLA_RS04415 bc9c3191c4e5f364e818751de6dffac0 255 PANTHER PTHR10992 11 253 8.0E-75 T 22-04-2016 TOLA_RS04415 bc9c3191c4e5f364e818751de6dffac0 255 SUPERFAMILY SSF53474 8 253 8.65E-49 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS04415 bc9c3191c4e5f364e818751de6dffac0 255 Gene3D G3DSA:3.40.50.1820 8 253 3.4E-52 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 312 1.2E-48 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 Gene3D G3DSA:1.10.8.60 318 418 1.6E-37 T 22-04-2016 TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 319 396 1.3E-15 T 22-04-2016 IPR019489 Clp ATPase, C-terminal TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 417 53.174 T 22-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 PANTHER PTHR11262 7 416 8.1E-249 T 22-04-2016 TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 Gene3D G3DSA:3.40.50.300 296 313 5.7E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 Gene3D G3DSA:3.40.50.300 67 255 5.7E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 SMART SM00994 13 52 1.0E-24 T 22-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 SMART SM00382 113 335 1.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 Pfam PF06689 ClpX C4-type zinc finger 14 51 3.0E-21 T 22-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 SMART SM01086 319 414 5.8E-34 T 22-04-2016 IPR019489 Clp ATPase, C-terminal TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 SUPERFAMILY SSF52540 65 405 3.24E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 SUPERFAMILY SSF57716 14 49 5.84E-12 T 22-04-2016 TOLA_RS05550 d0884e437d10c97e9ad9b6eaa33dd2de 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 413 1.2E-209 T 22-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 SUPERFAMILY SSF52402 197 420 1.19E-57 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 PRINTS PR00097 Anthranilate synthase component II signature 54 63 2.6E-6 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 PRINTS PR00097 Anthranilate synthase component II signature 177 190 2.6E-6 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 PRINTS PR00097 Anthranilate synthase component II signature 81 92 2.6E-6 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 525 56.511 T 22-04-2016 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 1.8E-7 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 177 190 1.8E-7 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 1.8E-7 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 Pfam PF02540 NAD synthase 220 292 8.2E-8 T 22-04-2016 IPR022310 NAD/GMP synthase TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 Gene3D G3DSA:3.40.50.880 4 223 5.6E-64 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 SUPERFAMILY SSF52317 7 237 2.53E-59 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 213 525 5.3E-154 T 22-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 Pfam PF00117 Glutamine amidotransferase class-I 12 199 2.3E-41 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 PANTHER PTHR11922 1 522 1.6E-292 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 Gene3D G3DSA:3.30.300.10 401 525 3.1E-53 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 Pfam PF00958 GMP synthase C terminal domain 433 524 2.9E-43 T 22-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 PANTHER PTHR11922:SF2 1 522 1.6E-292 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 205 8.4E-85 T 22-04-2016 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 SUPERFAMILY SSF54810 405 525 4.97E-51 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 Gene3D G3DSA:3.40.50.620 224 399 1.3E-56 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 4.4E-6 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 4.4E-6 T 22-04-2016 TOLA_RS11025 fddc332b4e27c757a2d9bc560242bec4 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 4.4E-6 T 22-04-2016 TOLA_RS14495 52ff3f4c84c59352ae16c440c27a03fc 628 Gene3D G3DSA:3.90.1310.10 129 251 4.6E-38 T 22-04-2016 TOLA_RS14495 52ff3f4c84c59352ae16c440c27a03fc 628 Pfam PF00905 Penicillin binding protein transpeptidase domain 270 609 1.6E-67 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TOLA_RS14495 52ff3f4c84c59352ae16c440c27a03fc 628 SUPERFAMILY SSF56519 55 251 3.14E-51 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TOLA_RS14495 52ff3f4c84c59352ae16c440c27a03fc 628 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 238 8.1E-46 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TOLA_RS14495 52ff3f4c84c59352ae16c440c27a03fc 628 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 18 612 6.8E-231 T 22-04-2016 IPR017790 Penicillin-binding protein 2 GO:0016020 UniPathway: UPA00219 TOLA_RS14495 52ff3f4c84c59352ae16c440c27a03fc 628 PANTHER PTHR30627:SF2 4 615 3.3E-235 T 22-04-2016 TOLA_RS14495 52ff3f4c84c59352ae16c440c27a03fc 628 Gene3D G3DSA:3.40.710.10 253 613 1.2E-96 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS14495 52ff3f4c84c59352ae16c440c27a03fc 628 SUPERFAMILY SSF56601 253 612 5.63E-89 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS14495 52ff3f4c84c59352ae16c440c27a03fc 628 PANTHER PTHR30627 4 615 3.3E-235 T 22-04-2016 TOLA_RS12540 3db8549022a125f8dd257a142109590d 359 PANTHER PTHR30438:SF1 11 359 4.0E-114 T 22-04-2016 TOLA_RS12540 3db8549022a125f8dd257a142109590d 359 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 62 82 1.6E-5 T 22-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TOLA_RS12540 3db8549022a125f8dd257a142109590d 359 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 331 346 1.6E-5 T 22-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TOLA_RS12540 3db8549022a125f8dd257a142109590d 359 SUPERFAMILY SSF111369 194 298 2.48E-6 T 22-04-2016 TOLA_RS12540 3db8549022a125f8dd257a142109590d 359 SUPERFAMILY SSF111369 123 158 2.48E-6 T 22-04-2016 TOLA_RS12540 3db8549022a125f8dd257a142109590d 359 Gene3D G3DSA:2.40.50.100 215 247 1.2E-10 T 22-04-2016 TOLA_RS12540 3db8549022a125f8dd257a142109590d 359 Gene3D G3DSA:2.40.50.100 52 84 1.2E-10 T 22-04-2016 TOLA_RS12540 3db8549022a125f8dd257a142109590d 359 Pfam PF13533 Biotin-lipoyl like 52 93 1.1E-7 T 22-04-2016 TOLA_RS12540 3db8549022a125f8dd257a142109590d 359 Pfam PF13437 HlyD family secretion protein 218 326 1.5E-13 T 22-04-2016 TOLA_RS12540 3db8549022a125f8dd257a142109590d 359 SUPERFAMILY SSF111369 44 123 4.97E-7 T 22-04-2016 TOLA_RS12540 3db8549022a125f8dd257a142109590d 359 PANTHER PTHR30438 11 359 4.0E-114 T 22-04-2016 TOLA_RS09220 dcd2e43db2cea43d9dc01860f76bc2e5 212 PANTHER PTHR23026 2 212 7.5E-41 T 22-04-2016 TOLA_RS09220 dcd2e43db2cea43d9dc01860f76bc2e5 212 Pfam PF00881 Nitroreductase family 9 186 6.7E-20 T 22-04-2016 IPR029479 Nitroreductase TOLA_RS09220 dcd2e43db2cea43d9dc01860f76bc2e5 212 SUPERFAMILY SSF55469 3 209 1.31E-47 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 TOLA_RS09220 dcd2e43db2cea43d9dc01860f76bc2e5 212 Gene3D G3DSA:3.40.109.10 1 210 9.5E-55 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 TOLA_RS09220 dcd2e43db2cea43d9dc01860f76bc2e5 212 PANTHER PTHR23026:SF101 2 212 7.5E-41 T 22-04-2016 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 6 21 3.7E-42 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 98 111 3.7E-42 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 77 93 3.7E-42 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 192 204 3.7E-42 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 112 132 3.7E-42 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 141 158 3.7E-42 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 PRINTS PR00732 Glycosyl hydrolase family 4 signature 166 177 3.7E-42 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 PANTHER PTHR32092:SF5 2 439 3.7E-201 T 22-04-2016 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 Gene3D G3DSA:3.90.110.10 170 435 4.4E-89 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 SUPERFAMILY SSF51735 4 169 4.98E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 196 411 1.2E-45 T 22-04-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 Pfam PF02056 Family 4 glycosyl hydrolase 6 186 3.3E-59 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 Gene3D G3DSA:3.40.50.720 3 169 8.1E-67 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 141 171 - T 22-04-2016 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 SUPERFAMILY SSF56327 172 436 1.03E-76 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TOLA_RS05600 d5add823ca78d58a13a29912ca5b9bb8 444 PANTHER PTHR32092 2 439 3.7E-201 T 22-04-2016 TOLA_RS07375 a38a813b8f10ff5b737a4b722cf3c0f0 208 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 9 193 1.8E-56 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 TOLA_RS07375 a38a813b8f10ff5b737a4b722cf3c0f0 208 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 2 194 24.273 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 TOLA_RS07375 a38a813b8f10ff5b737a4b722cf3c0f0 208 PIRSF PIRSF006091 1 205 8.0E-67 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 TOLA_RS07375 a38a813b8f10ff5b737a4b722cf3c0f0 208 Pfam PF04205 FMN-binding domain 100 188 1.4E-16 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 TOLA_RS07375 a38a813b8f10ff5b737a4b722cf3c0f0 208 PANTHER PTHR36118 1 204 7.8E-58 T 22-04-2016 TOLA_RS07375 a38a813b8f10ff5b737a4b722cf3c0f0 208 PANTHER PTHR36118:SF1 1 204 7.8E-58 T 22-04-2016 TOLA_RS07375 a38a813b8f10ff5b737a4b722cf3c0f0 208 SMART SM00900 100 192 3.3E-29 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 TOLA_RS03205 88283a095c54c0417447bd3ae5e8e8a6 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 233 1.6E-17 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS03205 88283a095c54c0417447bd3ae5e8e8a6 243 PANTHER PTHR26402:SF586 4 240 1.3E-134 T 22-04-2016 TOLA_RS03205 88283a095c54c0417447bd3ae5e8e8a6 243 SMART SM00448 4 114 3.7E-38 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS03205 88283a095c54c0417447bd3ae5e8e8a6 243 PANTHER PTHR26402 4 240 1.3E-134 T 22-04-2016 TOLA_RS03205 88283a095c54c0417447bd3ae5e8e8a6 243 Gene3D G3DSA:1.10.10.10 137 236 4.8E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS03205 88283a095c54c0417447bd3ae5e8e8a6 243 SMART SM00862 157 233 2.2E-15 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS03205 88283a095c54c0417447bd3ae5e8e8a6 243 SUPERFAMILY SSF46894 138 235 2.81E-21 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TOLA_RS03205 88283a095c54c0417447bd3ae5e8e8a6 243 SUPERFAMILY SSF52172 2 127 2.7E-36 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS03205 88283a095c54c0417447bd3ae5e8e8a6 243 Gene3D G3DSA:3.40.50.2300 2 125 4.0E-37 T 22-04-2016 TOLA_RS03205 88283a095c54c0417447bd3ae5e8e8a6 243 Pfam PF00072 Response regulator receiver domain 6 113 4.5E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 PIRSF PIRSF001480 21 413 7.5E-94 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 PANTHER PTHR10309:SF0 20 378 2.8E-102 T 22-04-2016 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 ProSitePatterns PS00965 Phosphomannose isomerase type I signature 1. 148 156 - T 22-04-2016 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 Gene3D G3DSA:2.60.120.10 261 296 1.7E-60 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 Gene3D G3DSA:2.60.120.10 28 162 1.7E-60 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 26 407 2.0E-75 T 22-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 Gene3D G3DSA:1.10.441.10 297 322 4.3E-19 T 22-04-2016 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 Gene3D G3DSA:1.10.441.10 163 254 4.3E-19 T 22-04-2016 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 PANTHER PTHR10309 20 378 2.8E-102 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 Gene3D G3DSA:2.60.120.10 341 403 2.2E-4 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 Pfam PF01238 Phosphomannose isomerase type I 26 189 5.6E-41 T 22-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 Pfam PF01238 Phosphomannose isomerase type I 219 375 2.4E-28 T 22-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 PRINTS PR00714 Phosphomannose isomerase type I signature 243 258 4.1E-60 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 PRINTS PR00714 Phosphomannose isomerase type I signature 148 171 4.1E-60 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 PRINTS PR00714 Phosphomannose isomerase type I signature 297 316 4.1E-60 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 PRINTS PR00714 Phosphomannose isomerase type I signature 278 297 4.1E-60 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 PRINTS PR00714 Phosphomannose isomerase type I signature 259 278 4.1E-60 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 PRINTS PR00714 Phosphomannose isomerase type I signature 103 124 4.1E-60 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 PRINTS PR00714 Phosphomannose isomerase type I signature 54 69 4.1E-60 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 PRINTS PR00714 Phosphomannose isomerase type I signature 26 44 4.1E-60 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 ProSitePatterns PS00966 Phosphomannose isomerase type I signature 2. 278 303 - T 22-04-2016 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07235 f19aaa845e5521ea6b090f6ad4d8390a 419 SUPERFAMILY SSF51182 25 396 4.62E-85 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS12825 f6e4776c54ce4846388bde57a5405955 167 SUPERFAMILY SSF101307 17 164 9.16E-46 T 22-04-2016 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 TOLA_RS12825 f6e4776c54ce4846388bde57a5405955 167 Pfam PF04608 Phosphatidylglycerophosphatase A 24 163 5.4E-52 T 22-04-2016 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 TOLA_RS12825 f6e4776c54ce4846388bde57a5405955 167 PANTHER PTHR36305 9 167 4.3E-67 T 22-04-2016 TOLA_RS12825 f6e4776c54ce4846388bde57a5405955 167 PIRSF PIRSF006162 14 167 2.7E-50 T 22-04-2016 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 TOLA_RS03200 7f35867fb4150403e4da04207fea039b 167 Hamap MF_00951 Transcription antitermination protein RfaH [rfaH]. 1 165 47.305 T 22-04-2016 IPR010215 Transcription antitermination protein RfaH GO:0006355 TOLA_RS03200 7f35867fb4150403e4da04207fea039b 167 PANTHER PTHR30265 1 151 4.3E-29 T 22-04-2016 TOLA_RS03200 7f35867fb4150403e4da04207fea039b 167 TIGRFAM TIGR01955 RfaH: transcription elongation factor/antiterminator RfaH 4 162 2.3E-47 T 22-04-2016 IPR010215 Transcription antitermination protein RfaH GO:0006355 TOLA_RS03200 7f35867fb4150403e4da04207fea039b 167 Gene3D G3DSA:3.30.70.940 1 101 2.0E-13 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 TOLA_RS03200 7f35867fb4150403e4da04207fea039b 167 SUPERFAMILY SSF82679 1 103 8.37E-26 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 TOLA_RS03200 7f35867fb4150403e4da04207fea039b 167 Pfam PF02357 Transcription termination factor nusG 2 91 9.2E-16 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 TOLA_RS03200 7f35867fb4150403e4da04207fea039b 167 PANTHER PTHR30265:SF3 1 151 4.3E-29 T 22-04-2016 TOLA_RS03200 7f35867fb4150403e4da04207fea039b 167 SMART SM00738 1 100 9.1E-12 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 TOLA_RS15040 f44c0f85505b91c1ece36a86167714de 262 PANTHER PTHR24220:SF368 7 262 4.4E-171 T 22-04-2016 TOLA_RS15040 f44c0f85505b91c1ece36a86167714de 262 SUPERFAMILY SSF52540 5 234 1.16E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15040 f44c0f85505b91c1ece36a86167714de 262 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS15040 f44c0f85505b91c1ece36a86167714de 262 SMART SM00382 30 204 1.7E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS15040 f44c0f85505b91c1ece36a86167714de 262 Gene3D G3DSA:3.40.50.300 3 242 5.8E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15040 f44c0f85505b91c1ece36a86167714de 262 Pfam PF00005 ABC transporter 21 170 3.3E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS15040 f44c0f85505b91c1ece36a86167714de 262 PANTHER PTHR24220 7 262 4.4E-171 T 22-04-2016 TOLA_RS08460 0610f2fd42f361019e960df34228cd65 246 PANTHER PTHR34148:SF1 1 246 1.6E-58 T 22-04-2016 TOLA_RS08460 0610f2fd42f361019e960df34228cd65 246 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 2 245 1.1E-55 T 22-04-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 TOLA_RS08460 0610f2fd42f361019e960df34228cd65 246 Pfam PF02654 Cobalamin-5-phosphate synthase 8 242 1.1E-54 T 22-04-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 TOLA_RS08460 0610f2fd42f361019e960df34228cd65 246 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 246 44.397 T 22-04-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 TOLA_RS08460 0610f2fd42f361019e960df34228cd65 246 PANTHER PTHR34148 1 246 1.6E-58 T 22-04-2016 TOLA_RS09990 a2274cc092aeacc54960c45477a5cfa8 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 271 3.4E-12 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09990 a2274cc092aeacc54960c45477a5cfa8 278 PANTHER PTHR30193 7 276 1.4E-37 T 22-04-2016 TOLA_RS09990 a2274cc092aeacc54960c45477a5cfa8 278 SUPERFAMILY SSF161098 9 264 2.24E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09990 a2274cc092aeacc54960c45477a5cfa8 278 Gene3D G3DSA:1.10.3720.10 16 272 1.4E-37 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09990 a2274cc092aeacc54960c45477a5cfa8 278 PANTHER PTHR30193:SF20 7 276 1.4E-37 T 22-04-2016 TOLA_RS09440 691a0b6ec6773013863b27bafa07e969 230 Pfam PF02682 Allophanate hydrolase subunit 1 20 214 1.3E-75 T 22-04-2016 IPR003833 Carboxyltransferase domain, subdomain C and D TOLA_RS09440 691a0b6ec6773013863b27bafa07e969 230 Gene3D G3DSA:2.40.100.10 100 226 2.4E-53 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS09440 691a0b6ec6773013863b27bafa07e969 230 SUPERFAMILY SSF160467 19 105 4.58E-13 T 22-04-2016 TOLA_RS09440 691a0b6ec6773013863b27bafa07e969 230 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 22 223 4.7E-79 T 22-04-2016 IPR010016 KipI family TOLA_RS09440 691a0b6ec6773013863b27bafa07e969 230 SUPERFAMILY SSF50891 100 226 1.97E-47 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS09440 691a0b6ec6773013863b27bafa07e969 230 SMART SM00796 16 214 5.4E-102 T 22-04-2016 IPR003833 Carboxyltransferase domain, subdomain C and D TOLA_RS09440 691a0b6ec6773013863b27bafa07e969 230 PANTHER PTHR34698:SF2 11 226 6.8E-90 T 22-04-2016 TOLA_RS09440 691a0b6ec6773013863b27bafa07e969 230 Gene3D G3DSA:3.30.1360.40 20 91 5.9E-11 T 22-04-2016 IPR024946 Arginine repressor C-terminal-like domain TOLA_RS09440 691a0b6ec6773013863b27bafa07e969 230 PANTHER PTHR34698 11 226 6.8E-90 T 22-04-2016 TOLA_RS10025 e6baf807bf31101c3e59d7de6d5ed924 227 PANTHER PTHR11749 1 224 1.7E-84 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS10025 e6baf807bf31101c3e59d7de6d5ed924 227 SUPERFAMILY SSF51366 1 205 5.18E-57 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TOLA_RS10025 e6baf807bf31101c3e59d7de6d5ed924 227 Pfam PF00834 Ribulose-phosphate 3 epimerase family 2 197 1.0E-63 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS10025 e6baf807bf31101c3e59d7de6d5ed924 227 PANTHER PTHR11749:SF3 1 224 1.7E-84 T 22-04-2016 TOLA_RS10025 e6baf807bf31101c3e59d7de6d5ed924 227 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 2 202 1.5E-65 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS10025 e6baf807bf31101c3e59d7de6d5ed924 227 Gene3D G3DSA:3.20.20.70 1 222 1.5E-76 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS10025 e6baf807bf31101c3e59d7de6d5ed924 227 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 132 154 - T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS10025 e6baf807bf31101c3e59d7de6d5ed924 227 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 29 43 - T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS02100 fbc9ce21dbc5026e83457374d058a600 601 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 10 596 1.4E-277 T 22-04-2016 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 TOLA_RS02100 fbc9ce21dbc5026e83457374d058a600 601 Pfam PF00364 Biotin-requiring enzyme 541 600 3.5E-17 T 22-04-2016 IPR000089 Biotin/lipoyl attachment TOLA_RS02100 fbc9ce21dbc5026e83457374d058a600 601 SUPERFAMILY SSF89000 300 458 1.14E-46 T 22-04-2016 TOLA_RS02100 fbc9ce21dbc5026e83457374d058a600 601 SUPERFAMILY SSF51569 3 303 2.2E-90 T 22-04-2016 TOLA_RS02100 fbc9ce21dbc5026e83457374d058a600 601 PANTHER PTHR18866 8 600 1.3E-224 T 22-04-2016 TOLA_RS02100 fbc9ce21dbc5026e83457374d058a600 601 Gene3D G3DSA:2.40.50.100 528 600 3.8E-24 T 22-04-2016 TOLA_RS02100 fbc9ce21dbc5026e83457374d058a600 601 Pfam PF00682 HMGL-like 8 273 1.6E-65 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 TOLA_RS02100 fbc9ce21dbc5026e83457374d058a600 601 Gene3D G3DSA:3.20.20.70 4 285 8.4E-114 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS02100 fbc9ce21dbc5026e83457374d058a600 601 SUPERFAMILY SSF51230 526 600 2.49E-21 T 22-04-2016 IPR011053 Single hybrid motif TOLA_RS02100 fbc9ce21dbc5026e83457374d058a600 601 PANTHER PTHR18866:SF109 8 600 1.3E-224 T 22-04-2016 TOLA_RS02100 fbc9ce21dbc5026e83457374d058a600 601 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 557 574 - T 22-04-2016 IPR001882 Biotin-binding site TOLA_RS02100 fbc9ce21dbc5026e83457374d058a600 601 Pfam PF02436 Conserved carboxylase domain 295 499 1.1E-54 T 22-04-2016 IPR003379 Carboxylase, conserved domain TOLA_RS06360 86a1afa7459e5c92c81ad18d2a18755e 245 SUPERFAMILY SSF89392 84 180 3.41E-5 T 22-04-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX TOLA_RS06360 86a1afa7459e5c92c81ad18d2a18755e 245 Gene3D G3DSA:2.50.20.10 17 240 9.9E-53 T 22-04-2016 TOLA_RS06360 86a1afa7459e5c92c81ad18d2a18755e 245 Pfam PF17131 Outer membrane lipoprotein-sorting protein 67 239 7.1E-39 T 22-04-2016 IPR033399 Putative outer membrane lipoprotein-sorting protein TOLA_RS02170 23573456773513d5dedf664a181f5816 292 PANTHER PTHR11820 1 290 2.4E-98 T 22-04-2016 TOLA_RS02170 23573456773513d5dedf664a181f5816 292 Gene3D G3DSA:3.90.850.10 68 283 2.1E-69 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 TOLA_RS02170 23573456773513d5dedf664a181f5816 292 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 76 277 2.8E-56 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 TOLA_RS02170 23573456773513d5dedf664a181f5816 292 SUPERFAMILY SSF56529 63 279 1.44E-68 T 22-04-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 TOLA_RS02170 23573456773513d5dedf664a181f5816 292 PANTHER PTHR11820:SF6 1 290 2.4E-98 T 22-04-2016 TOLA_RS13315 4605ceb7602216e804ea93c10b768ec5 209 Gene3D G3DSA:1.10.150.240 24 92 1.8E-5 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 TOLA_RS13315 4605ceb7602216e804ea93c10b768ec5 209 SUPERFAMILY SSF56784 9 202 9.22E-47 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13315 4605ceb7602216e804ea93c10b768ec5 209 Gene3D G3DSA:3.40.50.1000 7 23 2.6E-34 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13315 4605ceb7602216e804ea93c10b768ec5 209 Gene3D G3DSA:3.40.50.1000 95 203 2.6E-34 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13315 4605ceb7602216e804ea93c10b768ec5 209 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 189 1.8E-27 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13315 4605ceb7602216e804ea93c10b768ec5 209 PANTHER PTHR18901 8 203 1.4E-53 T 22-04-2016 TOLA_RS13315 4605ceb7602216e804ea93c10b768ec5 209 PANTHER PTHR18901:SF29 8 203 1.4E-53 T 22-04-2016 TOLA_RS13315 4605ceb7602216e804ea93c10b768ec5 209 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 77 190 5.1E-13 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS13315 4605ceb7602216e804ea93c10b768ec5 209 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 10 190 1.3E-48 T 22-04-2016 IPR010976 Beta-phosphoglucomutase hydrolase TOLA_RS06190 57ea858975657c0706a21b8614f54215 169 Pfam PF03459 TOBE domain 105 167 9.9E-12 T 22-04-2016 IPR005116 Transport-associated OB, type 1 TOLA_RS06190 57ea858975657c0706a21b8614f54215 169 Gene3D G3DSA:1.10.3720.10 23 99 1.3E-11 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06190 57ea858975657c0706a21b8614f54215 169 Gene3D G3DSA:2.40.50.100 100 165 3.0E-16 T 22-04-2016 TOLA_RS06190 57ea858975657c0706a21b8614f54215 169 SUPERFAMILY SSF50331 82 167 1.68E-12 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS06190 57ea858975657c0706a21b8614f54215 169 SUPERFAMILY SSF161098 12 87 2.75E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 PANTHER PTHR11573 6 748 0.0 T 22-04-2016 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 PANTHER PTHR11573:SF17 6 748 0.0 T 22-04-2016 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 SUPERFAMILY SSF51998 222 740 1.19E-168 T 22-04-2016 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 599 621 - T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 Pfam PF03477 ATP cone domain 6 92 4.5E-16 T 22-04-2016 IPR005144 ATP-cone domain TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 142 219 1.2E-14 T 22-04-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 Pfam PF02867 Ribonucleotide reductase, barrel domain 223 731 2.8E-116 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 145 735 1.2E-175 T 22-04-2016 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 Gene3D G3DSA:3.20.70.20 398 559 1.3E-42 T 22-04-2016 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 Gene3D G3DSA:3.20.70.20 610 697 1.3E-42 T 22-04-2016 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 Gene3D G3DSA:3.20.70.20 136 344 1.3E-42 T 22-04-2016 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 PRINTS PR01183 Ribonucleotide reductase large chain signature 539 562 5.5E-39 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 317 5.5E-39 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 PRINTS PR01183 Ribonucleotide reductase large chain signature 473 496 5.5E-39 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 PRINTS PR01183 Ribonucleotide reductase large chain signature 610 637 5.5E-39 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 PRINTS PR01183 Ribonucleotide reductase large chain signature 433 444 5.5E-39 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 PRINTS PR01183 Ribonucleotide reductase large chain signature 511 533 5.5E-39 T 22-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS07295 c641238332a1ba19d1f00548c4d6aabd 758 SUPERFAMILY SSF48168 10 221 8.11E-72 T 22-04-2016 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 SUPERFAMILY SSF51735 1 151 2.99E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 Pfam PF02080 TrkA-C domain 391 451 2.2E-11 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 Pfam PF02080 TrkA-C domain 156 225 2.0E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 Pfam PF02254 TrkA-N domain 235 350 1.1E-23 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 Pfam PF02254 TrkA-N domain 3 125 5.4E-26 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 Gene3D G3DSA:3.40.50.720 233 376 9.5E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 Gene3D G3DSA:3.40.50.720 1 152 1.9E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.65E-30 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 2.65E-30 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.65E-30 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.65E-30 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.65E-30 T 22-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 Gene3D G3DSA:3.30.70.1450 391 452 2.0E-5 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 Gene3D G3DSA:3.30.70.1450 154 226 0.001 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 SUPERFAMILY SSF116726 148 226 2.88E-9 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 SUPERFAMILY SSF116726 391 451 4.97E-9 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 SUPERFAMILY SSF51735 232 376 5.36E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 PANTHER PTHR13789 416 440 1.8E-75 T 22-04-2016 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 PANTHER PTHR13789 1 170 1.8E-75 T 22-04-2016 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 PANTHER PTHR13789:SF225 416 440 1.8E-75 T 22-04-2016 TOLA_RS00775 259324c8a76b57dd3b9954d93007aba7 458 PANTHER PTHR13789:SF225 1 170 1.8E-75 T 22-04-2016 TOLA_RS13360 46c8e8f69de3c1747d4ee8d06764f392 350 Pfam PF05175 Methyltransferase small domain 183 348 1.8E-58 T 22-04-2016 IPR007848 Methyltransferase small domain GO:0008168 TOLA_RS13360 46c8e8f69de3c1747d4ee8d06764f392 350 Gene3D G3DSA:3.40.50.150 182 347 6.7E-29 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS13360 46c8e8f69de3c1747d4ee8d06764f392 350 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 280 286 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TOLA_RS13360 46c8e8f69de3c1747d4ee8d06764f392 350 PANTHER PTHR18895:SF70 62 349 4.1E-80 T 22-04-2016 TOLA_RS13360 46c8e8f69de3c1747d4ee8d06764f392 350 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 277 289 5.8E-5 T 22-04-2016 TOLA_RS13360 46c8e8f69de3c1747d4ee8d06764f392 350 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 215 229 5.8E-5 T 22-04-2016 TOLA_RS13360 46c8e8f69de3c1747d4ee8d06764f392 350 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 295 319 5.8E-5 T 22-04-2016 TOLA_RS13360 46c8e8f69de3c1747d4ee8d06764f392 350 PANTHER PTHR18895 62 349 4.1E-80 T 22-04-2016 TOLA_RS13360 46c8e8f69de3c1747d4ee8d06764f392 350 Pfam PF08468 Methyltransferase small domain N-terminal 13 172 8.3E-40 T 22-04-2016 IPR013675 Methyltransferase small, N-terminal GO:0006364|GO:0008990 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS13360 46c8e8f69de3c1747d4ee8d06764f392 350 SUPERFAMILY SSF53335 179 339 1.28E-28 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS13360 46c8e8f69de3c1747d4ee8d06764f392 350 Hamap MF_01862 Ribosomal RNA small subunit methyltransferase C [rsmC]. 9 350 39.244 T 22-04-2016 IPR023543 rRNA small subunit methyltransferase C GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS08805 2f3ce30c35e04079440652379dbdba87 107 PANTHER PTHR34299 1 107 2.8E-27 T 22-04-2016 TOLA_RS08805 2f3ce30c35e04079440652379dbdba87 107 Pfam PF01219 Prokaryotic diacylglycerol kinase 1 98 6.4E-32 T 22-04-2016 IPR000829 Diacylglycerol kinase, prokaryotic GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 TOLA_RS08805 2f3ce30c35e04079440652379dbdba87 107 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 52 63 - T 22-04-2016 IPR000829 Diacylglycerol kinase, prokaryotic GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 TOLA_RS08805 2f3ce30c35e04079440652379dbdba87 107 Gene3D G3DSA:1.10.3830.10 1 102 4.6E-35 T 22-04-2016 TOLA_RS08805 2f3ce30c35e04079440652379dbdba87 107 PANTHER PTHR34299:SF1 1 107 2.8E-27 T 22-04-2016 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 113 1.4E-26 T 22-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 Gene3D G3DSA:3.20.190.10 2 130 2.1E-33 T 22-04-2016 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 Gene3D G3DSA:1.10.8.50 131 270 2.8E-51 T 22-04-2016 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 PANTHER PTHR22993:SF15 1 270 3.2E-126 T 22-04-2016 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 SUPERFAMILY SSF81624 2 139 8.37E-38 T 22-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 130 219 7.0E-30 T 22-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 SUPERFAMILY SSF57716 218 270 6.27E-17 T 22-04-2016 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 269 2.2E-89 T 22-04-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 PANTHER PTHR22993 1 270 3.2E-126 T 22-04-2016 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 ProSitePatterns PS01242 Zinc finger FPG-type signature. 245 269 - T 22-04-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 SUPERFAMILY SSF46946 131 222 4.06E-31 T 22-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 Pfam PF06827 Zinc finger found in FPG and IleRS 242 270 2.1E-7 T 22-04-2016 IPR010663 Zinc finger, FPG/IleRS-type TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 SMART SM01232 130 222 3.0E-49 T 22-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 270 42.897 T 22-04-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 TOLA_RS00680 0078e89e2a9cb008f7efa27214d11496 276 SMART SM00898 2 115 3.3E-46 T 22-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TOLA_RS00750 811aecf7ea4044bc5bec6c066ebb3907 286 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 4 286 29.757 T 22-04-2016 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 UniPathway: UPA00232 TOLA_RS00750 811aecf7ea4044bc5bec6c066ebb3907 286 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 66 88 - T 22-04-2016 IPR030470 UbiA prenyltransferase conserved site TOLA_RS00750 811aecf7ea4044bc5bec6c066ebb3907 286 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 9 285 1.5E-109 T 22-04-2016 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 UniPathway: UPA00232 TOLA_RS00750 811aecf7ea4044bc5bec6c066ebb3907 286 Pfam PF01040 UbiA prenyltransferase family 27 269 5.5E-63 T 22-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 TOLA_RS00750 811aecf7ea4044bc5bec6c066ebb3907 286 PANTHER PTHR11048 1 284 1.5E-85 T 22-04-2016 TOLA_RS12050 7c84d5583fd8bdd4a4f11d8294f6f736 267 Gene3D G3DSA:1.10.8.100 201 264 1.1E-21 T 22-04-2016 IPR023165 rRNA adenine dimethylase-like TOLA_RS12050 7c84d5583fd8bdd4a4f11d8294f6f736 267 Pfam PF00398 Ribosomal RNA adenine dimethylase 9 264 3.0E-73 T 22-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TOLA_RS12050 7c84d5583fd8bdd4a4f11d8294f6f736 267 PANTHER PTHR11727 8 263 1.1E-88 T 22-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TOLA_RS12050 7c84d5583fd8bdd4a4f11d8294f6f736 267 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 41 68 - T 22-04-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TOLA_RS12050 7c84d5583fd8bdd4a4f11d8294f6f736 267 SUPERFAMILY SSF53335 8 264 3.28E-76 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS12050 7c84d5583fd8bdd4a4f11d8294f6f736 267 Gene3D G3DSA:3.40.50.150 8 197 5.6E-68 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS12050 7c84d5583fd8bdd4a4f11d8294f6f736 267 SMART SM00650 25 197 4.6E-81 T 22-04-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TOLA_RS12050 7c84d5583fd8bdd4a4f11d8294f6f736 267 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 9 263 1.2E-86 T 22-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TOLA_RS12050 7c84d5583fd8bdd4a4f11d8294f6f736 267 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 9 264 54.256 T 22-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 PANTHER PTHR10046:SF43 11 777 0.0 T 22-04-2016 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 677 685 - T 22-04-2016 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 704 723 2.2E-55 T 22-04-2016 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 727 745 2.2E-55 T 22-04-2016 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 596 612 2.2E-55 T 22-04-2016 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 674 693 2.2E-55 T 22-04-2016 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 357 376 2.2E-55 T 22-04-2016 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 Gene3D G3DSA:3.40.50.300 314 501 8.1E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 Gene3D G3DSA:1.10.8.60 502 585 2.8E-34 T 22-04-2016 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 PANTHER PTHR10046 11 777 0.0 T 22-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 SMART SM00382 349 493 1.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 SUPERFAMILY SSF52540 315 587 1.26E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 PIRSF PIRSF001174 1 775 0.0 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 SUPERFAMILY SSF54211 596 772 2.84E-60 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 571 773 2.6E-97 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 Hamap MF_01973 Lon protease [lon]. 11 773 70.766 T 22-04-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 10 195 8.4E-43 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 TIGRFAM TIGR00763 lon: endopeptidase La 12 772 4.3E-304 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 SUPERFAMILY SSF88697 10 201 8.45E-48 T 22-04-2016 IPR015947 PUA-like domain TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 SMART SM00464 10 202 1.1E-70 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 353 490 3.5E-17 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS05555 ff377f179ad948d1b1a60ddbf14878e9 782 Gene3D G3DSA:3.30.230.10 592 772 8.0E-78 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS16150 1947589c8595f927c57aa617c4647151 293 PANTHER PTHR12715:SF8 1 293 1.9E-53 T 22-04-2016 TOLA_RS16150 1947589c8595f927c57aa617c4647151 293 Pfam PF00892 EamA-like transporter family 4 139 1.5E-15 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS16150 1947589c8595f927c57aa617c4647151 293 Pfam PF00892 EamA-like transporter family 148 280 9.7E-19 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS16150 1947589c8595f927c57aa617c4647151 293 SUPERFAMILY SSF103481 189 282 4.38E-13 T 22-04-2016 TOLA_RS16150 1947589c8595f927c57aa617c4647151 293 PANTHER PTHR12715 1 293 1.9E-53 T 22-04-2016 TOLA_RS16150 1947589c8595f927c57aa617c4647151 293 SUPERFAMILY SSF103481 37 140 7.19E-6 T 22-04-2016 TOLA_RS10210 f91b8c5289feee733d5100d689d27722 214 Gene3D G3DSA:3.60.15.10 3 209 4.1E-61 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS10210 f91b8c5289feee733d5100d689d27722 214 PANTHER PTHR11935 1 209 2.3E-118 T 22-04-2016 TOLA_RS10210 f91b8c5289feee733d5100d689d27722 214 PANTHER PTHR11935:SF115 1 209 2.3E-118 T 22-04-2016 TOLA_RS10210 f91b8c5289feee733d5100d689d27722 214 Pfam PF00753 Metallo-beta-lactamase superfamily 10 193 1.8E-33 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS10210 f91b8c5289feee733d5100d689d27722 214 SUPERFAMILY SSF56281 3 209 1.31E-58 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS10210 f91b8c5289feee733d5100d689d27722 214 SMART SM00849 13 193 1.9E-41 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 Pfam PF00580 UvrD/REP helicase N-terminal domain 3 267 5.7E-78 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 Pfam PF13361 UvrD-like helicase C-terminal domain 273 618 2.8E-68 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 Gene3D G3DSA:3.40.50.300 184 281 1.8E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 Gene3D G3DSA:3.40.50.300 2 104 1.8E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 Gene3D G3DSA:1.10.486.10 385 522 1.9E-39 T 22-04-2016 TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 PANTHER PTHR11070:SF19 1 514 0.0 T 22-04-2016 TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 PANTHER PTHR11070:SF19 530 672 0.0 T 22-04-2016 TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 TIGRFAM TIGR01074 rep: ATP-dependent DNA helicase Rep 2 673 0.0 T 22-04-2016 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 PANTHER PTHR11070 1 514 0.0 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 PANTHER PTHR11070 530 672 0.0 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 SUPERFAMILY SSF52540 1 644 5.93E-162 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 1 673 40.492 T 22-04-2016 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 Gene3D G3DSA:1.10.10.160 108 183 2.2E-21 T 22-04-2016 IPR013986 DExx box DNA helicase domain TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 Gene3D G3DSA:3.40.50.300 555 645 8.2E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01400 c1097125109ce9fc692d65b01db75acd 676 Gene3D G3DSA:3.40.50.300 282 384 8.2E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08820 6643ab5a56c312cf88199dc26b980142 298 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 155 176 - T 22-04-2016 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 TOLA_RS08820 6643ab5a56c312cf88199dc26b980142 298 SUPERFAMILY SSF54913 225 297 1.56E-22 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta TOLA_RS08820 6643ab5a56c312cf88199dc26b980142 298 Gene3D G3DSA:3.30.70.120 225 297 1.1E-30 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TOLA_RS08820 6643ab5a56c312cf88199dc26b980142 298 PANTHER PTHR21403 1 298 1.4E-122 T 22-04-2016 IPR001348 ATP phosphoribosyltransferase HisG GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 TOLA_RS08820 6643ab5a56c312cf88199dc26b980142 298 Pfam PF08029 HisG, C-terminal domain 222 295 2.9E-25 T 22-04-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 TOLA_RS08820 6643ab5a56c312cf88199dc26b980142 298 Gene3D G3DSA:3.40.190.10 2 138 5.9E-50 T 22-04-2016 TOLA_RS08820 6643ab5a56c312cf88199dc26b980142 298 Pfam PF01634 ATP phosphoribosyltransferase 53 218 1.0E-44 T 22-04-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 TOLA_RS08820 6643ab5a56c312cf88199dc26b980142 298 SUPERFAMILY SSF53850 5 223 5.43E-65 T 22-04-2016 TOLA_RS08820 6643ab5a56c312cf88199dc26b980142 298 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 203 297 1.9E-30 T 22-04-2016 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 TOLA_RS08820 6643ab5a56c312cf88199dc26b980142 298 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 6 196 5.6E-55 T 22-04-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 TOLA_RS08820 6643ab5a56c312cf88199dc26b980142 298 PANTHER PTHR21403:SF0 1 298 1.4E-122 T 22-04-2016 TOLA_RS08820 6643ab5a56c312cf88199dc26b980142 298 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 5 298 34.776 T 22-04-2016 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 TOLA_RS14665 7e6a0ae739b6cf666fb31581ee74813b 365 Pfam PF13477 Glycosyl transferase 4-like 3 147 4.1E-14 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain TOLA_RS14665 7e6a0ae739b6cf666fb31581ee74813b 365 PANTHER PTHR12526 69 365 2.8E-34 T 22-04-2016 TOLA_RS14665 7e6a0ae739b6cf666fb31581ee74813b 365 Gene3D G3DSA:3.40.50.2000 185 336 5.7E-19 T 22-04-2016 TOLA_RS14665 7e6a0ae739b6cf666fb31581ee74813b 365 Pfam PF00534 Glycosyl transferases group 1 188 340 2.0E-24 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 TOLA_RS14665 7e6a0ae739b6cf666fb31581ee74813b 365 SUPERFAMILY SSF53756 22 363 2.87E-55 T 22-04-2016 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 1.0E-15 T 22-04-2016 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 1.0E-15 T 22-04-2016 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 1.0E-15 T 22-04-2016 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.0E-15 T 22-04-2016 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 Gene3D G3DSA:3.50.50.60 1 110 3.4E-18 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 Gene3D G3DSA:3.50.50.60 111 337 1.2E-54 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 PANTHER PTHR22912:SF140 2 462 2.9E-178 T 22-04-2016 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 Gene3D G3DSA:3.30.390.30 357 467 1.5E-38 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 351 452 1.5E-11 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 SMART SM00450 474 568 3.7E-15 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 SUPERFAMILY SSF51905 2 198 4.16E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 Gene3D G3DSA:3.40.250.10 483 563 3.9E-22 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 PANTHER PTHR22912 2 462 2.9E-178 T 22-04-2016 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 SUPERFAMILY SSF55424 345 467 1.27E-30 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 2.2E-23 T 22-04-2016 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 2.2E-23 T 22-04-2016 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 2.2E-23 T 22-04-2016 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.2E-23 T 22-04-2016 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 2.2E-23 T 22-04-2016 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 SUPERFAMILY SSF52821 482 563 8.77E-23 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 305 6.0E-56 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 Pfam PF00581 Rhodanese-like domain 484 563 1.7E-7 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS01655 2d4b635b1f8f328f888707ce95aa3c11 569 SUPERFAMILY SSF51905 149 338 1.75E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02115 40f0a35e573b517387c9007295ceb657 283 SUPERFAMILY SSF103481 172 273 6.54E-14 T 22-04-2016 TOLA_RS02115 40f0a35e573b517387c9007295ceb657 283 SUPERFAMILY SSF103481 42 132 5.75E-11 T 22-04-2016 TOLA_RS02115 40f0a35e573b517387c9007295ceb657 283 Pfam PF00892 EamA-like transporter family 4 129 6.6E-12 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS02115 40f0a35e573b517387c9007295ceb657 283 Pfam PF00892 EamA-like transporter family 138 270 5.1E-17 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS02115 40f0a35e573b517387c9007295ceb657 283 PANTHER PTHR32322:SF2 4 270 2.9E-32 T 22-04-2016 TOLA_RS02115 40f0a35e573b517387c9007295ceb657 283 PANTHER PTHR32322 4 270 2.9E-32 T 22-04-2016 TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 4.2E-7 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 4.2E-7 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 Pfam PF13377 Periplasmic binding protein-like domain 168 329 1.4E-36 T 22-04-2016 TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 SUPERFAMILY SSF53822 61 331 5.26E-80 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 SUPERFAMILY SSF47413 1 57 1.88E-16 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 Gene3D G3DSA:1.10.260.40 2 57 3.4E-24 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 PANTHER PTHR30146 1 330 1.3E-147 T 22-04-2016 TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 Gene3D G3DSA:3.40.50.2300 167 330 4.1E-51 T 22-04-2016 TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.1E-19 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 SMART SM00354 1 71 4.2E-27 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 PANTHER PTHR30146:SF55 1 330 1.3E-147 T 22-04-2016 TOLA_RS13415 4d7122158bb2dc23ef17a57b3fe3afb2 337 Gene3D G3DSA:3.40.50.2300 58 166 2.5E-44 T 22-04-2016 TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 Gene3D G3DSA:3.30.470.20 204 443 5.9E-101 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 444 1.8E-242 T 22-04-2016 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 Gene3D G3DSA:3.40.50.20 1 129 5.6E-51 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 SUPERFAMILY SSF56059 83 346 2.65E-70 T 22-04-2016 TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.7E-44 T 22-04-2016 IPR005481 Biotin carboxylase-like, N-terminal domain TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 2.9E-85 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 Gene3D G3DSA:3.30.1490.20 130 203 1.1E-29 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 SUPERFAMILY SSF51246 331 443 3.45E-44 T 22-04-2016 IPR011054 Rudiment single hybrid motif TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 SUPERFAMILY SSF52440 1 113 6.4E-46 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 PANTHER PTHR18866 1 440 4.4E-302 T 22-04-2016 TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 SMART SM00878 336 441 5.0E-64 T 22-04-2016 IPR005482 Biotin carboxylase, C-terminal TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS12880 ef0e3e88cd8473fe7f07ed78f8a7bb62 446 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 3.2E-38 T 22-04-2016 IPR005482 Biotin carboxylase, C-terminal TOLA_RS06910 d4dc963f2abd5b1448590adb71f5a327 224 PANTHER PTHR24220 6 223 4.6E-87 T 22-04-2016 TOLA_RS06910 d4dc963f2abd5b1448590adb71f5a327 224 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS06910 d4dc963f2abd5b1448590adb71f5a327 224 SUPERFAMILY SSF52540 16 223 3.38E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06910 d4dc963f2abd5b1448590adb71f5a327 224 Gene3D G3DSA:3.40.50.300 4 223 4.6E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06910 d4dc963f2abd5b1448590adb71f5a327 224 Pfam PF00005 ABC transporter 24 172 5.7E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS06910 d4dc963f2abd5b1448590adb71f5a327 224 PANTHER PTHR24220:SF86 6 223 4.6E-87 T 22-04-2016 TOLA_RS06910 d4dc963f2abd5b1448590adb71f5a327 224 SMART SM00382 32 221 1.5E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS06995 93741332d13d92d5f28ebc324f533a5f 238 Pfam PF04397 LytTr DNA-binding domain 143 235 5.6E-24 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 TOLA_RS06995 93741332d13d92d5f28ebc324f533a5f 238 Gene3D G3DSA:2.40.50.40 134 198 1.1E-12 T 22-04-2016 TOLA_RS06995 93741332d13d92d5f28ebc324f533a5f 238 SMART SM00448 2 112 3.6E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS06995 93741332d13d92d5f28ebc324f533a5f 238 Gene3D G3DSA:3.40.50.2300 1 118 6.6E-30 T 22-04-2016 TOLA_RS06995 93741332d13d92d5f28ebc324f533a5f 238 PANTHER PTHR26402:SF501 2 120 1.4E-32 T 22-04-2016 TOLA_RS06995 93741332d13d92d5f28ebc324f533a5f 238 PANTHER PTHR26402 2 120 1.4E-32 T 22-04-2016 TOLA_RS06995 93741332d13d92d5f28ebc324f533a5f 238 Pfam PF00072 Response regulator receiver domain 4 112 2.6E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS06995 93741332d13d92d5f28ebc324f533a5f 238 Gene3D G3DSA:2.20.25.10 216 237 4.8E-4 T 22-04-2016 TOLA_RS06995 93741332d13d92d5f28ebc324f533a5f 238 SMART SM00850 142 236 4.6E-24 T 22-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 TOLA_RS06995 93741332d13d92d5f28ebc324f533a5f 238 SUPERFAMILY SSF52172 1 120 8.25E-31 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 Pfam PF01612 3'-5' exonuclease 4 170 3.5E-30 T 22-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 Gene3D G3DSA:1.10.150.80 218 281 6.7E-5 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 PANTHER PTHR12124 1 341 1.2E-57 T 22-04-2016 TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 Hamap MF_01899 Ribonuclease D [rnd]. 3 364 38.647 T 22-04-2016 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 Pfam PF00570 HRDC domain 213 279 1.3E-14 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 SMART SM00474 3 171 2.6E-30 T 22-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 PANTHER PTHR12124:SF42 1 341 1.2E-57 T 22-04-2016 TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 Gene3D G3DSA:3.30.420.10 3 181 1.9E-11 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 SUPERFAMILY SSF47819 196 301 1.2E-21 T 22-04-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 SUPERFAMILY SSF47819 296 363 5.89E-13 T 22-04-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 TIGRFAM TIGR01388 rnd: ribonuclease D 8 363 4.5E-97 T 22-04-2016 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 SMART SM00341 210 289 1.4E-5 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 TOLA_RS07970 f8d2297912c65a0f15c42bdfc37c8da6 365 SUPERFAMILY SSF53098 2 209 9.23E-54 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS03980 fe3c764af4eec5578226fec7e913df3f 215 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 39 48 - T 22-04-2016 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562|UniPathway: UPA00227|UniPathway: UPA00856 TOLA_RS03980 fe3c764af4eec5578226fec7e913df3f 215 SUPERFAMILY SSF51569 5 210 2.01E-69 T 22-04-2016 TOLA_RS03980 fe3c764af4eec5578226fec7e913df3f 215 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 127 140 - T 22-04-2016 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TOLA_RS03980 fe3c764af4eec5578226fec7e913df3f 215 Pfam PF01081 KDPG and KHG aldolase 13 202 1.4E-77 T 22-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TOLA_RS03980 fe3c764af4eec5578226fec7e913df3f 215 PANTHER PTHR30246 1 211 1.5E-105 T 22-04-2016 TOLA_RS03980 fe3c764af4eec5578226fec7e913df3f 215 Gene3D G3DSA:3.20.20.70 9 212 7.0E-80 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS03980 fe3c764af4eec5578226fec7e913df3f 215 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 209 1.6E-82 T 22-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TOLA_RS03980 fe3c764af4eec5578226fec7e913df3f 215 PANTHER PTHR30246:SF0 1 211 1.5E-105 T 22-04-2016 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 Gene3D G3DSA:3.40.50.720 1 111 2.4E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 PIRSF PIRSF036426 1 463 3.8E-197 T 22-04-2016 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 Gene3D G3DSA:3.30.160.110 112 146 7.0E-19 T 22-04-2016 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 219 233 - T 22-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 Gene3D G3DSA:1.10.8.210 148 208 3.8E-20 T 22-04-2016 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 216 425 7.2E-50 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 PANTHER PTHR21091:SF16 1 19 3.7E-78 T 22-04-2016 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 PANTHER PTHR21091:SF16 182 443 3.7E-78 T 22-04-2016 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 PANTHER PTHR21091 1 19 3.7E-78 T 22-04-2016 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 PANTHER PTHR21091 182 443 3.7E-78 T 22-04-2016 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 Pfam PF13241 Putative NAD(P)-binding 6 113 8.4E-28 T 22-04-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 SUPERFAMILY SSF53790 211 454 1.96E-78 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 294 327 - T 22-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 Gene3D G3DSA:3.40.1010.10 214 329 2.2E-45 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 Hamap MF_01646 Siroheme synthase [cysG]. 1 456 51.262 T 22-04-2016 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 214 446 5.4E-91 T 22-04-2016 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 SUPERFAMILY SSF75615 112 198 2.75E-25 T 22-04-2016 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 SUPERFAMILY SSF51735 1 111 1.09E-23 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 Pfam PF14824 Sirohaem biosynthesis protein central 119 143 4.5E-7 T 22-04-2016 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 Pfam PF10414 Sirohaem synthase dimerisation region 148 206 6.8E-18 T 22-04-2016 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 206 1.7E-72 T 22-04-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS12955 02ed9dd0aaec8da5207354e957e3d674 468 Gene3D G3DSA:3.30.950.10 330 464 1.4E-49 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 TOLA_RS02995 acd12ce37a025cd08e53d7b8a8c2b030 115 Gene3D G3DSA:2.60.300.12 7 101 4.7E-32 T 22-04-2016 IPR000361 FeS cluster biogenesis TOLA_RS02995 acd12ce37a025cd08e53d7b8a8c2b030 115 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 96 113 - T 22-04-2016 IPR017870 FeS cluster insertion, C-terminal, conserved site TOLA_RS02995 acd12ce37a025cd08e53d7b8a8c2b030 115 PANTHER PTHR10072 10 115 3.4E-47 T 22-04-2016 TOLA_RS02995 acd12ce37a025cd08e53d7b8a8c2b030 115 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 115 35.819 T 22-04-2016 IPR023063 FeS cluster insertion protein ErpA GO:0016226 TOLA_RS02995 acd12ce37a025cd08e53d7b8a8c2b030 115 Pfam PF01521 Iron-sulphur cluster biosynthesis 10 110 1.4E-19 T 22-04-2016 IPR000361 FeS cluster biogenesis TOLA_RS02995 acd12ce37a025cd08e53d7b8a8c2b030 115 SUPERFAMILY SSF89360 4 101 8.44E-31 T 22-04-2016 IPR000361 FeS cluster biogenesis TOLA_RS02995 acd12ce37a025cd08e53d7b8a8c2b030 115 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 10 115 7.0E-39 T 22-04-2016 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 TOLA_RS08870 7d24cd680e59a15c76e4d948f8d59b54 483 SUPERFAMILY SSF56954 1 28 3.01E-93 T 22-04-2016 TOLA_RS08870 7d24cd680e59a15c76e4d948f8d59b54 483 SUPERFAMILY SSF56954 58 468 3.01E-93 T 22-04-2016 TOLA_RS08870 7d24cd680e59a15c76e4d948f8d59b54 483 Gene3D G3DSA:2.20.200.10 104 144 1.2E-17 T 22-04-2016 TOLA_RS08870 7d24cd680e59a15c76e4d948f8d59b54 483 Gene3D G3DSA:2.20.200.10 318 353 1.2E-17 T 22-04-2016 TOLA_RS08870 7d24cd680e59a15c76e4d948f8d59b54 483 PANTHER PTHR30203:SF6 1 483 6.0E-138 T 22-04-2016 TOLA_RS08870 7d24cd680e59a15c76e4d948f8d59b54 483 Gene3D G3DSA:1.20.1600.10 53 93 1.0E-77 T 22-04-2016 TOLA_RS08870 7d24cd680e59a15c76e4d948f8d59b54 483 Gene3D G3DSA:1.20.1600.10 354 468 1.0E-77 T 22-04-2016 TOLA_RS08870 7d24cd680e59a15c76e4d948f8d59b54 483 Gene3D G3DSA:1.20.1600.10 145 317 1.0E-77 T 22-04-2016 TOLA_RS08870 7d24cd680e59a15c76e4d948f8d59b54 483 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 467 1.1E-127 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 TOLA_RS08870 7d24cd680e59a15c76e4d948f8d59b54 483 Pfam PF02321 Outer membrane efflux protein 281 465 1.0E-27 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS08870 7d24cd680e59a15c76e4d948f8d59b54 483 Pfam PF02321 Outer membrane efflux protein 67 257 1.2E-20 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS08870 7d24cd680e59a15c76e4d948f8d59b54 483 PANTHER PTHR30203 1 483 6.0E-138 T 22-04-2016 TOLA_RS10005 2fa7c60beb63ac67927551ab07cd2862 65 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 47 2.9E-19 T 22-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TOLA_RS10005 2fa7c60beb63ac67927551ab07cd2862 65 Pfam PF02416 mttA/Hcf106 family 3 47 7.5E-13 T 22-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TOLA_RS10005 2fa7c60beb63ac67927551ab07cd2862 65 PANTHER PTHR33162 2 49 6.4E-14 T 22-04-2016 TOLA_RS10005 2fa7c60beb63ac67927551ab07cd2862 65 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 65 18.881 T 22-04-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 PANTHER PTHR32063 2 1036 0.0 T 22-04-2016 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 PRINTS PR00702 Acriflavin resistance protein family signature 442 465 6.1E-33 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 6.1E-33 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 PRINTS PR00702 Acriflavin resistance protein family signature 467 490 6.1E-33 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 6.1E-33 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 6.1E-33 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 PRINTS PR00702 Acriflavin resistance protein family signature 331 354 6.1E-33 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 6.1E-33 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 PRINTS PR00702 Acriflavin resistance protein family signature 541 558 6.1E-33 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 Gene3D G3DSA:3.30.2090.10 711 800 2.4E-15 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 SUPERFAMILY SSF82693 137 182 4.71E-20 T 22-04-2016 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 Gene3D G3DSA:1.10.3850.10 274 496 4.2E-71 T 22-04-2016 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 Gene3D G3DSA:1.10.3850.10 802 1030 2.4E-54 T 22-04-2016 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 SUPERFAMILY SSF82714 183 265 1.09E-18 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 Gene3D G3DSA:3.30.2090.10 183 265 8.9E-20 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 Gene3D G3DSA:3.30.70.1430 46 142 5.8E-23 T 22-04-2016 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 SUPERFAMILY SSF82693 268 325 4.71E-20 T 22-04-2016 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 SUPERFAMILY SSF82866 291 495 3.01E-42 T 22-04-2016 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1035 0.0 T 22-04-2016 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 Pfam PF00873 AcrB/AcrD/AcrF family 7 1029 4.5E-244 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 SUPERFAMILY SSF82693 46 128 9.42E-20 T 22-04-2016 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 SUPERFAMILY SSF82866 795 1033 6.15E-50 T 22-04-2016 TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 SUPERFAMILY SSF82714 712 796 1.44E-14 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS15335 caf929b7c9808a66a0500430d5eb1d3d 1036 PANTHER PTHR32063:SF19 2 1036 0.0 T 22-04-2016 TOLA_RS15380 07c60a25a52a4814494e74a1f632d982 215 Pfam PF02508 Rnf-Nqr subunit, membrane protein 9 194 2.5E-62 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 TOLA_RS15380 07c60a25a52a4814494e74a1f632d982 215 PANTHER PTHR30586:SF1 2 215 1.4E-136 T 22-04-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 TOLA_RS15380 07c60a25a52a4814494e74a1f632d982 215 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 5 207 1.3E-99 T 22-04-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 TOLA_RS15380 07c60a25a52a4814494e74a1f632d982 215 PANTHER PTHR30586 2 215 1.4E-136 T 22-04-2016 TOLA_RS15380 07c60a25a52a4814494e74a1f632d982 215 Hamap MF_00428 Na(+)-translocating NADH-quinone reductase subunit D [nqrD]. 2 207 35.76 T 22-04-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 TOLA_RS15380 07c60a25a52a4814494e74a1f632d982 215 PIRSF PIRSF006102 3 214 8.2E-69 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 TOLA_RS13190 5bc2d8b57a2164117dbc85008a5129aa 168 Pfam PF04353 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ 1 149 4.4E-50 T 22-04-2016 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 TOLA_RS13190 5bc2d8b57a2164117dbc85008a5129aa 168 PIRSF PIRSF016548 1 162 1.0E-46 T 22-04-2016 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 SUPERFAMILY SSF69304 157 428 1.05E-51 T 22-04-2016 TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 Gene3D G3DSA:3.40.50.10070 21 150 2.2E-48 T 22-04-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 Hamap MF_00671 Protein TolB [tolB]. 1 426 34.945 T 22-04-2016 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 PANTHER PTHR11731:SF123 1 118 1.8E-100 T 22-04-2016 TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 PANTHER PTHR11731:SF123 160 428 1.8E-100 T 22-04-2016 TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 Pfam PF04052 TolB amino-terminal domain 22 122 2.0E-30 T 22-04-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 Pfam PF07676 WD40-like Beta Propeller Repeat 282 315 3.2E-11 T 22-04-2016 IPR011659 WD40-like Beta Propeller TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 Pfam PF07676 WD40-like Beta Propeller Repeat 196 228 7.7E-8 T 22-04-2016 IPR011659 WD40-like Beta Propeller TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 Pfam PF07676 WD40-like Beta Propeller Repeat 243 272 6.9E-9 T 22-04-2016 IPR011659 WD40-like Beta Propeller TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 Pfam PF07676 WD40-like Beta Propeller Repeat 334 358 0.15 T 22-04-2016 IPR011659 WD40-like Beta Propeller TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 Pfam PF07676 WD40-like Beta Propeller Repeat 371 392 0.12 T 22-04-2016 IPR011659 WD40-like Beta Propeller TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 SUPERFAMILY SSF52964 27 161 8.63E-39 T 22-04-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 Gene3D G3DSA:2.130.10.10 151 428 1.3E-71 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 PANTHER PTHR11731 1 118 1.8E-100 T 22-04-2016 TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 PANTHER PTHR11731 160 428 1.8E-100 T 22-04-2016 TOLA_RS13795 22ea6d5853d637edf011243480f7dbda 431 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 13 427 1.2E-156 T 22-04-2016 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 Gene3D G3DSA:1.10.287.970 1 88 8.0E-33 T 22-04-2016 IPR027460 Aerobic respiration control sensor protein ArcB, transmembrane domain TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 PRINTS PR00344 Bacterial sensor protein C-terminal signature 468 486 9.6E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 449 9.6E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 505 9.6E-12 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 Gene3D G3DSA:1.10.287.130 274 342 2.1E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 Gene3D G3DSA:1.20.120.160 674 771 1.7E-26 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 SUPERFAMILY SSF52172 528 644 1.57E-25 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 SUPERFAMILY SSF47384 268 347 4.71E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 PIRSF PIRSF003182 1 776 0.0 T 22-04-2016 IPR014409 Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB GO:0000155|GO:0000160|GO:0004673|GO:0016021 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 SUPERFAMILY SSF55874 336 506 2.49E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 Pfam PF00072 Response regulator receiver domain 530 640 5.1E-18 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 Gene3D G3DSA:3.30.565.10 348 508 2.7E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 SMART SM00091 155 221 2.3E-5 T 22-04-2016 IPR000014 PAS domain TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 PANTHER PTHR24423:SF476 11 95 8.3E-255 T 22-04-2016 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 PANTHER PTHR24423:SF476 153 675 8.3E-255 T 22-04-2016 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 Pfam PF01627 Hpt domain 684 768 6.0E-12 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 Pfam PF00989 PAS fold 157 266 2.9E-16 T 22-04-2016 IPR013767 PAS fold GO:0006355 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 SUPERFAMILY SSF47226 660 771 3.93E-24 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 PANTHER PTHR24423 11 95 8.3E-255 T 22-04-2016 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 PANTHER PTHR24423 153 675 8.3E-255 T 22-04-2016 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 Gene3D G3DSA:3.30.450.20 142 267 2.1E-23 T 22-04-2016 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 SUPERFAMILY SSF55785 142 267 1.92E-24 T 22-04-2016 IPR000014 PAS domain TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 SMART SM00073 673 770 3.7E-10 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 395 506 6.0E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 152 276 2.7E-16 T 22-04-2016 IPR000014 PAS domain TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 Pfam PF00512 His Kinase A (phospho-acceptor) domain 283 346 3.4E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 SMART SM00448 528 640 1.9E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 SMART SM00388 282 347 4.0E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 Gene3D G3DSA:3.40.50.2300 526 644 8.8E-28 T 22-04-2016 TOLA_RS03190 3deb49734eee6d4275a4b523e0f7c1f5 782 SMART SM00387 394 508 1.8E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS08310 355eba4c252b9f9a4ae9530ae95cc620 256 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 25 250 2.8E-59 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS08310 355eba4c252b9f9a4ae9530ae95cc620 256 SMART SM00062 23 252 2.8E-57 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS08310 355eba4c252b9f9a4ae9530ae95cc620 256 Gene3D G3DSA:3.40.190.10 21 110 2.6E-40 T 22-04-2016 TOLA_RS08310 355eba4c252b9f9a4ae9530ae95cc620 256 Gene3D G3DSA:3.40.190.10 211 252 2.6E-40 T 22-04-2016 TOLA_RS08310 355eba4c252b9f9a4ae9530ae95cc620 256 PANTHER PTHR18966 23 249 4.8E-49 T 22-04-2016 TOLA_RS08310 355eba4c252b9f9a4ae9530ae95cc620 256 SUPERFAMILY SSF53850 1 253 7.88E-62 T 22-04-2016 TOLA_RS08310 355eba4c252b9f9a4ae9530ae95cc620 256 Gene3D G3DSA:3.40.190.10 117 206 3.5E-15 T 22-04-2016 TOLA_RS08310 355eba4c252b9f9a4ae9530ae95cc620 256 PANTHER PTHR18966:SF152 23 249 4.8E-49 T 22-04-2016 TOLA_RS11755 b158a273659ccb515e9d48c27324d94f 184 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 1 184 1.2E-47 T 22-04-2016 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 TOLA_RS11755 b158a273659ccb515e9d48c27324d94f 184 Gene3D G3DSA:2.50.20.10 6 184 4.1E-56 T 22-04-2016 TOLA_RS11755 b158a273659ccb515e9d48c27324d94f 184 PANTHER PTHR35869 1 184 3.0E-46 T 22-04-2016 TOLA_RS11755 b158a273659ccb515e9d48c27324d94f 184 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 14 173 6.2E-47 T 22-04-2016 IPR004564 Outer membrane lipoprotein carrier protein LolA-like TOLA_RS11755 b158a273659ccb515e9d48c27324d94f 184 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 1 183 27.453 T 22-04-2016 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 TOLA_RS11755 b158a273659ccb515e9d48c27324d94f 184 SUPERFAMILY SSF89392 6 184 2.39E-50 T 22-04-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX TOLA_RS13845 75cb1cb45ec34370093407fd77965b0f 173 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 153 48.012 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TOLA_RS13845 75cb1cb45ec34370093407fd77965b0f 173 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 156 3.2E-71 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TOLA_RS13845 75cb1cb45ec34370093407fd77965b0f 173 PANTHER PTHR30194 1 169 6.8E-72 T 22-04-2016 TOLA_RS13845 75cb1cb45ec34370093407fd77965b0f 173 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 22-04-2016 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 TOLA_RS13845 75cb1cb45ec34370093407fd77965b0f 173 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 150 2.7E-63 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TOLA_RS13845 75cb1cb45ec34370093407fd77965b0f 173 Gene3D G3DSA:3.30.420.10 3 156 8.1E-68 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS13845 75cb1cb45ec34370093407fd77965b0f 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 5.0E-42 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TOLA_RS13845 75cb1cb45ec34370093407fd77965b0f 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 5.0E-42 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TOLA_RS13845 75cb1cb45ec34370093407fd77965b0f 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 5.0E-42 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TOLA_RS13845 75cb1cb45ec34370093407fd77965b0f 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 5.0E-42 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TOLA_RS13845 75cb1cb45ec34370093407fd77965b0f 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 5.0E-42 T 22-04-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TOLA_RS13845 75cb1cb45ec34370093407fd77965b0f 173 SUPERFAMILY SSF53098 3 156 2.01E-54 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS00085 8a15a4f6cad9b209f4a0ae388f7d0f7d 318 PANTHER PTHR30126 1 309 3.4E-148 T 22-04-2016 TOLA_RS00085 8a15a4f6cad9b209f4a0ae388f7d0f7d 318 Pfam PF03466 LysR substrate binding domain 90 292 1.7E-41 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS00085 8a15a4f6cad9b209f4a0ae388f7d0f7d 318 SUPERFAMILY SSF46785 2 113 3.99E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00085 8a15a4f6cad9b209f4a0ae388f7d0f7d 318 PANTHER PTHR30126:SF6 1 309 3.4E-148 T 22-04-2016 TOLA_RS00085 8a15a4f6cad9b209f4a0ae388f7d0f7d 318 Gene3D G3DSA:1.10.10.10 2 81 7.3E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00085 8a15a4f6cad9b209f4a0ae388f7d0f7d 318 Gene3D G3DSA:3.40.190.10 91 179 5.0E-24 T 22-04-2016 TOLA_RS00085 8a15a4f6cad9b209f4a0ae388f7d0f7d 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 2.3E-14 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS00085 8a15a4f6cad9b209f4a0ae388f7d0f7d 318 SUPERFAMILY SSF53850 91 293 1.02E-41 T 22-04-2016 TOLA_RS00085 8a15a4f6cad9b209f4a0ae388f7d0f7d 318 Gene3D G3DSA:3.40.190.10 180 260 6.3E-25 T 22-04-2016 TOLA_RS00085 8a15a4f6cad9b209f4a0ae388f7d0f7d 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.8E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS00085 8a15a4f6cad9b209f4a0ae388f7d0f7d 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.8E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS00085 8a15a4f6cad9b209f4a0ae388f7d0f7d 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.8E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS05025 62bbdb08c03d1300467dcf6e320af4fb 530 PANTHER PTHR19211:SF38 2 527 0.0 T 22-04-2016 TOLA_RS05025 62bbdb08c03d1300467dcf6e320af4fb 530 Pfam PF00005 ABC transporter 336 467 1.7E-22 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS05025 62bbdb08c03d1300467dcf6e320af4fb 530 Pfam PF00005 ABC transporter 18 184 6.6E-19 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS05025 62bbdb08c03d1300467dcf6e320af4fb 530 SUPERFAMILY SSF52540 297 524 2.67E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05025 62bbdb08c03d1300467dcf6e320af4fb 530 Pfam PF12848 ABC transporter 224 309 1.8E-21 T 22-04-2016 IPR032781 ABC-transporter extension domain TOLA_RS05025 62bbdb08c03d1300467dcf6e320af4fb 530 SMART SM00382 26 228 1.7E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS05025 62bbdb08c03d1300467dcf6e320af4fb 530 SMART SM00382 344 512 1.4E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS05025 62bbdb08c03d1300467dcf6e320af4fb 530 SUPERFAMILY SSF52540 125 244 4.42E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05025 62bbdb08c03d1300467dcf6e320af4fb 530 SUPERFAMILY SSF52540 2 92 4.42E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05025 62bbdb08c03d1300467dcf6e320af4fb 530 Gene3D G3DSA:3.40.50.300 318 528 4.1E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05025 62bbdb08c03d1300467dcf6e320af4fb 530 PANTHER PTHR19211 2 527 0.0 T 22-04-2016 TOLA_RS05025 62bbdb08c03d1300467dcf6e320af4fb 530 Gene3D G3DSA:3.40.50.300 4 280 6.5E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 Pfam PF01909 Nucleotidyltransferase domain 71 100 7.6E-6 T 22-04-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 SUPERFAMILY SSF81301 24 174 2.13E-22 T 22-04-2016 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 PIRSF PIRSF006288 7 878 0.0 T 22-04-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 PANTHER PTHR13734:SF45 93 691 4.4E-130 T 22-04-2016 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 SMART SM00471 448 595 4.0E-7 T 22-04-2016 IPR003607 HD/PDEase domain TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 Pfam PF08335 GlnD PII-uridylyltransferase 178 316 5.0E-34 T 22-04-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 Gene3D G3DSA:3.30.460.10 71 167 3.2E-7 T 22-04-2016 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 32 872 5.0E-295 T 22-04-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 SUPERFAMILY SSF81593 187 311 8.63E-11 T 22-04-2016 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 878 317.44 T 22-04-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 Gene3D G3DSA:1.10.3210.10 422 612 1.4E-26 T 22-04-2016 IPR006674 HD domain TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 PANTHER PTHR13734 93 691 4.4E-130 T 22-04-2016 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 Gene3D G3DSA:3.30.70.260 801 858 3.0E-7 T 22-04-2016 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 Gene3D G3DSA:3.30.70.260 697 747 4.3E-5 T 22-04-2016 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 SUPERFAMILY SSF55021 801 865 5.0E-7 T 22-04-2016 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 SUPERFAMILY SSF55021 693 750 2.46E-7 T 22-04-2016 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 SUPERFAMILY SSF109604 419 573 5.02E-15 T 22-04-2016 TOLA_RS10745 761b3b8e3dcf04e3c71e10d5544448d9 878 Pfam PF01966 HD domain 454 584 1.9E-12 T 22-04-2016 IPR006674 HD domain TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 SUPERFAMILY SSF53738 155 256 5.49E-28 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 PANTHER PTHR22573 2 441 2.1E-161 T 22-04-2016 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 22-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 441 2.5E-13 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 9.8E-13 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 9.8E-13 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 9.8E-13 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 Gene3D G3DSA:3.40.120.10 250 365 1.8E-30 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 363 6.8E-30 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 SUPERFAMILY SSF53738 2 180 7.06E-48 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 SUPERFAMILY SSF55957 357 443 1.57E-20 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 PANTHER PTHR22573:SF15 2 441 2.1E-161 T 22-04-2016 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 SUPERFAMILY SSF53738 257 363 2.51E-30 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 Gene3D G3DSA:3.40.120.10 175 249 2.7E-24 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 Gene3D G3DSA:3.40.120.10 3 151 4.0E-47 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 Gene3D G3DSA:3.30.310.50 368 442 1.5E-15 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 441 2.2E-186 T 22-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 253 1.5E-18 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 134 2.5E-44 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS14630 074f7aa03e65fa5ae003c97a3ec4fcb1 445 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 443 46.343 T 22-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS01210 a23d11fd751340e839e229409bfedfaa 175 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 10 171 2.0E-63 T 22-04-2016 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530|UniPathway: UPA00792 TOLA_RS01210 a23d11fd751340e839e229409bfedfaa 175 PANTHER PTHR11603 10 173 8.2E-77 T 22-04-2016 TOLA_RS01210 a23d11fd751340e839e229409bfedfaa 175 Gene3D G3DSA:3.40.50.300 9 171 2.3E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01210 a23d11fd751340e839e229409bfedfaa 175 SUPERFAMILY SSF52540 9 171 1.58E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01210 a23d11fd751340e839e229409bfedfaa 175 Pfam PF01202 Shikimate kinase 17 170 4.8E-12 T 22-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 PANTHER PTHR21248:SF9 21 487 8.0E-171 T 22-04-2016 TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 SUPERFAMILY SSF56024 275 473 6.95E-41 T 22-04-2016 TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 Pfam PF13396 Phospholipase_D-nuclease N-terminal 22 62 3.6E-6 T 22-04-2016 IPR027379 Cardiolipin synthase N-terminal TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 SUPERFAMILY SSF56024 69 316 1.97E-52 T 22-04-2016 TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 Hamap MF_00190 Cardiolipin synthase A [clsA]. 5 487 49.39 T 22-04-2016 IPR030840 Cardiolipin synthase A GO:0008808|GO:0016780|GO:0032049 TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 Gene3D G3DSA:3.30.870.10 317 462 6.1E-36 T 22-04-2016 TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 Pfam PF13091 PLD-like domain 327 446 6.0E-24 T 22-04-2016 IPR025202 Phospholipase D-like domain TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 Pfam PF13091 PLD-like domain 137 249 9.6E-14 T 22-04-2016 IPR025202 Phospholipase D-like domain TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 Gene3D G3DSA:3.30.870.10 115 316 6.8E-40 T 22-04-2016 TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 SMART SM00155 222 249 1.6E-4 T 22-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 SMART SM00155 400 427 5.1E-6 T 22-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 13 487 8.6E-136 T 22-04-2016 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 TOLA_RS03280 5100bda89eb94e6fe5008c99097c8705 487 PANTHER PTHR21248 21 487 8.0E-171 T 22-04-2016 TOLA_RS01035 abfce76f71f45fcf05659e26fefaf889 154 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 2 151 9.6E-47 T 22-04-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC TOLA_RS01035 abfce76f71f45fcf05659e26fefaf889 154 Pfam PF04073 Aminoacyl-tRNA editing domain 32 142 4.7E-20 T 22-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TOLA_RS01035 abfce76f71f45fcf05659e26fefaf889 154 PIRSF PIRSF006181 1 154 9.7E-46 T 22-04-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC TOLA_RS01035 abfce76f71f45fcf05659e26fefaf889 154 Gene3D G3DSA:3.90.960.10 1 152 9.5E-45 T 22-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TOLA_RS01035 abfce76f71f45fcf05659e26fefaf889 154 SUPERFAMILY SSF55826 2 151 7.33E-31 T 22-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TOLA_RS01035 abfce76f71f45fcf05659e26fefaf889 154 PANTHER PTHR30411 1 151 7.8E-42 T 22-04-2016 TOLA_RS01035 abfce76f71f45fcf05659e26fefaf889 154 PANTHER PTHR30411:SF0 1 151 7.8E-42 T 22-04-2016 TOLA_RS10650 36804ebdb857d17b41ce88957ef6f023 196 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 8 188 3.5E-31 T 22-04-2016 IPR023473 AMMECR1 TOLA_RS10650 36804ebdb857d17b41ce88957ef6f023 196 PANTHER PTHR13016 13 186 1.7E-29 T 22-04-2016 IPR023473 AMMECR1 TOLA_RS10650 36804ebdb857d17b41ce88957ef6f023 196 Gene3D G3DSA:3.30.1490.150 127 181 1.3E-16 T 22-04-2016 TOLA_RS10650 36804ebdb857d17b41ce88957ef6f023 196 Pfam PF01871 AMMECR1 17 185 1.9E-40 T 22-04-2016 IPR002733 AMMECR1 domain TOLA_RS10650 36804ebdb857d17b41ce88957ef6f023 196 Gene3D G3DSA:3.30.700.20 8 126 8.6E-35 T 22-04-2016 IPR027485 AMMECR1, N-terminal TOLA_RS10650 36804ebdb857d17b41ce88957ef6f023 196 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 14 186 3.5E-61 T 22-04-2016 IPR027623 AmmeMemoRadiSam system protein A TOLA_RS10650 36804ebdb857d17b41ce88957ef6f023 196 SUPERFAMILY SSF143447 6 189 1.57E-53 T 22-04-2016 IPR002733 AMMECR1 domain TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 PANTHER PTHR10322 155 776 1.8E-155 T 22-04-2016 TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 Pfam PF03104 DNA polymerase family B, exonuclease domain 151 304 1.2E-12 T 22-04-2016 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 SUPERFAMILY SSF56672 393 786 3.0E-114 T 22-04-2016 TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 Pfam PF00136 DNA polymerase family B 387 785 3.5E-44 T 22-04-2016 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 Gene3D G3DSA:3.90.1600.10 420 439 1.4E-9 T 22-04-2016 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 Gene3D G3DSA:3.90.1600.10 519 651 1.4E-9 T 22-04-2016 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 Gene3D G3DSA:3.30.420.10 155 373 8.0E-35 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 ProSitePatterns PS00116 DNA polymerase family B signature. 550 558 - T 22-04-2016 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 SMART SM00486 155 562 8.7E-57 T 22-04-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 423 436 3.1E-10 T 22-04-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 496 508 3.1E-10 T 22-04-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 548 556 3.1E-10 T 22-04-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS10910 c82be826a1d242c45ae8d9c8afc83cbc 791 SUPERFAMILY SSF53098 6 397 2.78E-77 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS04780 8ca6dc7fa7c8785c7d3e32676ee2c2a9 246 Gene3D G3DSA:3.40.50.300 48 215 2.0E-26 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04780 8ca6dc7fa7c8785c7d3e32676ee2c2a9 246 PANTHER PTHR30050 57 216 1.0E-19 T 22-04-2016 TOLA_RS04780 8ca6dc7fa7c8785c7d3e32676ee2c2a9 246 PANTHER PTHR30050 10 19 1.0E-19 T 22-04-2016 TOLA_RS04780 8ca6dc7fa7c8785c7d3e32676ee2c2a9 246 Pfam PF01695 IstB-like ATP binding protein 49 216 7.1E-15 T 22-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 TOLA_RS04780 8ca6dc7fa7c8785c7d3e32676ee2c2a9 246 SUPERFAMILY SSF52540 64 216 4.73E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04780 8ca6dc7fa7c8785c7d3e32676ee2c2a9 246 SMART SM00382 96 229 6.9E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS07325 35c48ce477e747b377246966bcff81f3 175 PIRSF PIRSF001338 6 175 3.8E-63 T 22-04-2016 IPR024694 N5-carboxyaminoimidazole ribonucleotide mutase PurE GO:0006189|GO:0034023 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234|UniPathway: UPA00074 TOLA_RS07325 35c48ce477e747b377246966bcff81f3 175 SUPERFAMILY SSF52255 10 170 5.36E-63 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 TOLA_RS07325 35c48ce477e747b377246966bcff81f3 175 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 11 168 30.341 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 TOLA_RS07325 35c48ce477e747b377246966bcff81f3 175 Pfam PF00731 AIR carboxylase 11 161 3.1E-61 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 TOLA_RS07325 35c48ce477e747b377246966bcff81f3 175 PANTHER PTHR23046:SF2 2 175 1.6E-78 T 22-04-2016 TOLA_RS07325 35c48ce477e747b377246966bcff81f3 175 SMART SM01001 9 164 4.3E-97 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 TOLA_RS07325 35c48ce477e747b377246966bcff81f3 175 PANTHER PTHR23046 2 175 1.6E-78 T 22-04-2016 TOLA_RS07325 35c48ce477e747b377246966bcff81f3 175 Gene3D G3DSA:3.40.50.7700 3 169 2.9E-73 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 TOLA_RS07325 35c48ce477e747b377246966bcff81f3 175 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 11 168 5.0E-61 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 Gene3D G3DSA:1.10.260.40 2 53 8.3E-26 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 Gene3D G3DSA:3.40.50.2300 54 174 3.7E-45 T 22-04-2016 TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 SMART SM00354 1 71 6.2E-35 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 PANTHER PTHR30146:SF38 1 331 9.5E-192 T 22-04-2016 TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 PANTHER PTHR30146 1 331 9.5E-192 T 22-04-2016 TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 SUPERFAMILY SSF53822 60 331 4.17E-94 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 Pfam PF13377 Periplasmic binding protein-like domain 169 330 1.8E-43 T 22-04-2016 TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 SUPERFAMILY SSF47413 2 59 2.16E-18 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 4.6E-6 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 4.6E-6 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 Gene3D G3DSA:3.40.50.2300 175 310 9.6E-58 T 22-04-2016 TOLA_RS02975 1f147e895f095cfcb14ffd380d2a5c5b 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.7E-21 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS15600 6a1f7b4c996c3c72603a592ca07c770a 259 Pfam PF01925 Sulfite exporter TauE/SafE 7 256 2.1E-40 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 TOLA_RS15600 6a1f7b4c996c3c72603a592ca07c770a 259 PANTHER PTHR30269:SF2 1 256 6.4E-46 T 22-04-2016 TOLA_RS15600 6a1f7b4c996c3c72603a592ca07c770a 259 PANTHER PTHR30269 1 256 6.4E-46 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 Gene3D G3DSA:1.10.460.10 488 604 1.5E-51 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 Gene3D G3DSA:1.10.460.10 152 211 1.5E-51 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 663 1.5E-222 T 22-04-2016 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 SUPERFAMILY SSF57783 617 652 1.28E-8 T 22-04-2016 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 SMART SM00493 1 122 2.0E-24 T 22-04-2016 IPR006171 Toprim domain TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 Gene3D G3DSA:1.10.290.10 281 408 4.5E-33 T 22-04-2016 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 SMART SM00437 271 556 1.0E-61 T 22-04-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 Pfam PF01131 DNA topoisomerase 152 590 7.1E-112 T 22-04-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 Gene3D G3DSA:3.40.50.140 1 145 7.6E-47 T 22-04-2016 IPR006171 Toprim domain TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 SMART SM00436 122 217 7.2E-33 T 22-04-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 308 323 - T 22-04-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 PANTHER PTHR11390 1 501 1.2E-154 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 PANTHER PTHR11390 519 654 1.2E-154 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 Gene3D G3DSA:3.30.65.10 618 652 4.0E-8 T 22-04-2016 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 SUPERFAMILY SSF56712 1 604 1.57E-178 T 22-04-2016 IPR023405 DNA topoisomerase, type IA, core domain TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 187 205 5.8E-25 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 395 411 5.8E-25 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 314 323 5.8E-25 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 96 109 5.8E-25 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 519 533 5.8E-25 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 Pfam PF01751 Toprim domain 3 129 6.9E-16 T 22-04-2016 IPR006171 Toprim domain TOLA_RS12235 3667dcba8b0aefceb8703ae105802db0 669 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 618 652 6.2E-9 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 TOLA_RS14685 5908bebe083d597a5e1ed4311c988871 719 Pfam PF13807 G-rich domain on putative tyrosine kinase 369 450 3.6E-34 T 22-04-2016 IPR032807 Tyrosine kinase, G-rich domain TOLA_RS14685 5908bebe083d597a5e1ed4311c988871 719 Gene3D G3DSA:3.40.50.300 524 700 5.7E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14685 5908bebe083d597a5e1ed4311c988871 719 PANTHER PTHR32309 18 122 9.8E-238 T 22-04-2016 TOLA_RS14685 5908bebe083d597a5e1ed4311c988871 719 PANTHER PTHR32309 187 719 9.8E-238 T 22-04-2016 TOLA_RS14685 5908bebe083d597a5e1ed4311c988871 719 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 527 698 8.0E-9 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TOLA_RS14685 5908bebe083d597a5e1ed4311c988871 719 Pfam PF02706 Chain length determinant protein 18 254 3.2E-37 T 22-04-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 TOLA_RS14685 5908bebe083d597a5e1ed4311c988871 719 SUPERFAMILY SSF52540 524 700 1.77E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14685 5908bebe083d597a5e1ed4311c988871 719 PANTHER PTHR32309:SF17 18 122 9.8E-238 T 22-04-2016 TOLA_RS14685 5908bebe083d597a5e1ed4311c988871 719 PANTHER PTHR32309:SF17 187 719 9.8E-238 T 22-04-2016 TOLA_RS14685 5908bebe083d597a5e1ed4311c988871 719 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 505 710 1.9E-44 T 22-04-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 Gene3D G3DSA:3.40.50.300 153 319 7.0E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 SUPERFAMILY SSF52540 129 378 5.33E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 Pfam PF12137 RNA polymerase recycling family C-terminal 598 956 1.9E-145 T 22-04-2016 IPR022737 RNA polymerase recycling, bacterial, C-terminal GO:0016817 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 PANTHER PTHR10799:SF610 792 831 7.3E-226 T 22-04-2016 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 PANTHER PTHR10799:SF610 150 354 7.3E-226 T 22-04-2016 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 PANTHER PTHR10799:SF610 1 9 7.3E-226 T 22-04-2016 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 PANTHER PTHR10799:SF610 387 688 7.3E-226 T 22-04-2016 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 PANTHER PTHR10799:SF610 883 959 7.3E-226 T 22-04-2016 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 Gene3D G3DSA:3.40.50.300 477 621 8.8E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 SMART SM00487 150 342 2.2E-16 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 PANTHER PTHR10799 792 831 7.3E-226 T 22-04-2016 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 PANTHER PTHR10799 150 354 7.3E-226 T 22-04-2016 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 PANTHER PTHR10799 1 9 7.3E-226 T 22-04-2016 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 PANTHER PTHR10799 387 688 7.3E-226 T 22-04-2016 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 PANTHER PTHR10799 883 959 7.3E-226 T 22-04-2016 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 SUPERFAMILY SSF52540 472 637 4.11E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 SUPERFAMILY SSF52540 273 337 4.11E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 SMART SM00490 509 593 5.9E-15 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 Pfam PF00271 Helicase conserved C-terminal domain 483 593 1.4E-14 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 Hamap MF_01821 RNA polymerase-associated protein RapA [rapA]. 1 957 67.395 T 22-04-2016 IPR023949 RNA polymerase-associated protein RapA GO:0006355 TOLA_RS12010 1beda530e6bb1048be87a3c04ed6643b 959 Pfam PF00176 SNF2 family N-terminal domain 174 342 7.1E-14 T 22-04-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 TOLA_RS00285 aa39153c87c45dff8319baefba96a21d 481 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 253 434 2.3E-33 T 22-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TOLA_RS00285 aa39153c87c45dff8319baefba96a21d 481 PANTHER PTHR10196:SF72 1 471 1.5E-197 T 22-04-2016 TOLA_RS00285 aa39153c87c45dff8319baefba96a21d 481 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 242 6.4E-70 T 22-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TOLA_RS00285 aa39153c87c45dff8319baefba96a21d 481 Gene3D G3DSA:3.30.420.40 245 473 1.3E-50 T 22-04-2016 TOLA_RS00285 aa39153c87c45dff8319baefba96a21d 481 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 346 366 - T 22-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 TOLA_RS00285 aa39153c87c45dff8319baefba96a21d 481 SUPERFAMILY SSF53067 2 245 2.18E-74 T 22-04-2016 TOLA_RS00285 aa39153c87c45dff8319baefba96a21d 481 Gene3D G3DSA:3.30.420.40 1 242 6.9E-66 T 22-04-2016 TOLA_RS00285 aa39153c87c45dff8319baefba96a21d 481 TIGRFAM TIGR01312 XylB: xylulokinase 3 472 1.1E-171 T 22-04-2016 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 TOLA_RS00285 aa39153c87c45dff8319baefba96a21d 481 PANTHER PTHR10196 1 471 1.5E-197 T 22-04-2016 TOLA_RS00285 aa39153c87c45dff8319baefba96a21d 481 SUPERFAMILY SSF53067 244 476 8.64E-54 T 22-04-2016 TOLA_RS00285 aa39153c87c45dff8319baefba96a21d 481 PIRSF PIRSF000538 1 480 7.7E-134 T 22-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 TOLA_RS00285 aa39153c87c45dff8319baefba96a21d 481 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 127 139 - T 22-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 TOLA_RS04450 cbb7c7909817b504612cfe23f2145a75 537 SUPERFAMILY SSF53850 33 535 1.05E-130 T 22-04-2016 TOLA_RS04450 cbb7c7909817b504612cfe23f2145a75 537 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 79 101 - T 22-04-2016 IPR023765 Solute-binding protein family 5, conserved site TOLA_RS04450 cbb7c7909817b504612cfe23f2145a75 537 PIRSF PIRSF002741 8 537 1.0E-97 T 22-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TOLA_RS04450 cbb7c7909817b504612cfe23f2145a75 537 Gene3D G3DSA:3.10.105.10 305 507 1.7E-61 T 22-04-2016 TOLA_RS04450 cbb7c7909817b504612cfe23f2145a75 537 Gene3D G3DSA:3.40.190.10 153 304 6.3E-37 T 22-04-2016 TOLA_RS04450 cbb7c7909817b504612cfe23f2145a75 537 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 454 4.2E-91 T 22-04-2016 IPR000914 Solute-binding protein family 5 domain TOLA_RS04450 cbb7c7909817b504612cfe23f2145a75 537 PANTHER PTHR30290:SF28 32 537 2.5E-175 T 22-04-2016 TOLA_RS04450 cbb7c7909817b504612cfe23f2145a75 537 PANTHER PTHR30290 32 537 2.5E-175 T 22-04-2016 TOLA_RS10515 0510f5600f37342e78520300a80b69b5 1253 SUPERFAMILY SSF52540 1064 1233 1.58E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10515 0510f5600f37342e78520300a80b69b5 1253 Gene3D G3DSA:3.40.50.300 466 499 3.9E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10515 0510f5600f37342e78520300a80b69b5 1253 Gene3D G3DSA:3.40.50.300 1110 1234 3.9E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10515 0510f5600f37342e78520300a80b69b5 1253 SUPERFAMILY SSF52540 1 314 3.19E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10515 0510f5600f37342e78520300a80b69b5 1253 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1151 1212 3.9E-12 T 22-04-2016 TOLA_RS10515 0510f5600f37342e78520300a80b69b5 1253 PANTHER PTHR32114:SF2 2 749 2.3E-105 T 22-04-2016 TOLA_RS10515 0510f5600f37342e78520300a80b69b5 1253 PANTHER PTHR32114:SF2 843 1253 2.3E-105 T 22-04-2016 TOLA_RS10515 0510f5600f37342e78520300a80b69b5 1253 PANTHER PTHR32114 2 749 2.3E-105 T 22-04-2016 IPR027050 Nuclease SbcCD subunit C GO:0004518|GO:0006281 TOLA_RS10515 0510f5600f37342e78520300a80b69b5 1253 PANTHER PTHR32114 843 1253 2.3E-105 T 22-04-2016 IPR027050 Nuclease SbcCD subunit C GO:0004518|GO:0006281 TOLA_RS10515 0510f5600f37342e78520300a80b69b5 1253 Gene3D G3DSA:3.40.50.300 1 182 4.4E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10515 0510f5600f37342e78520300a80b69b5 1253 Pfam PF13476 AAA domain 7 259 1.1E-27 T 22-04-2016 TOLA_RS05055 9f31361d6013036b108b3d493bf80726 130 PANTHER PTHR11922 1 110 7.6E-26 T 22-04-2016 TOLA_RS05055 9f31361d6013036b108b3d493bf80726 130 Gene3D G3DSA:3.40.50.880 1 107 1.5E-23 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS05055 9f31361d6013036b108b3d493bf80726 130 SUPERFAMILY SSF52317 1 103 1.35E-21 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS05055 9f31361d6013036b108b3d493bf80726 130 PANTHER PTHR11922:SF11 1 110 7.6E-26 T 22-04-2016 TOLA_RS15425 213fcb046f73f43b2177ed22a5816cc8 504 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 157 182 - T 22-04-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 TOLA_RS15425 213fcb046f73f43b2177ed22a5816cc8 504 PANTHER PTHR11819:SF148 4 484 9.1E-187 T 22-04-2016 TOLA_RS15425 213fcb046f73f43b2177ed22a5816cc8 504 PANTHER PTHR11819 4 484 9.1E-187 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 TOLA_RS15425 213fcb046f73f43b2177ed22a5816cc8 504 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 7 490 1.6E-217 T 22-04-2016 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 TOLA_RS15425 213fcb046f73f43b2177ed22a5816cc8 504 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 419 439 - T 22-04-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 TOLA_RS15425 213fcb046f73f43b2177ed22a5816cc8 504 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 437 1.5E-117 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 TOLA_RS15425 213fcb046f73f43b2177ed22a5816cc8 504 Pfam PF00474 Sodium:solute symporter family 35 437 2.2E-134 T 22-04-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 TOLA_RS16120 c19b71feab60b11ade83d73b8b05f888 263 PANTHER PTHR13696 2 261 2.0E-91 T 22-04-2016 TOLA_RS16120 c19b71feab60b11ade83d73b8b05f888 263 SUPERFAMILY SSF52540 2 256 1.0E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS16120 c19b71feab60b11ade83d73b8b05f888 263 PANTHER PTHR13696:SF52 2 261 2.0E-91 T 22-04-2016 TOLA_RS16120 c19b71feab60b11ade83d73b8b05f888 263 Gene3D G3DSA:3.40.50.300 3 260 6.2E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS16120 c19b71feab60b11ade83d73b8b05f888 263 Pfam PF13614 AAA domain 2 178 8.2E-64 T 22-04-2016 IPR025669 AAA domain TOLA_RS02960 b4a89134ab88b38e366b107e9937fc46 328 PANTHER PTHR32196:SF21 14 323 6.5E-138 T 22-04-2016 TOLA_RS02960 b4a89134ab88b38e366b107e9937fc46 328 PANTHER PTHR32196 14 323 6.5E-138 T 22-04-2016 TOLA_RS02960 b4a89134ab88b38e366b107e9937fc46 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 319 4.1E-51 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS01320 647b7f3d7a9e9ecfdb345362ffb85060 265 PANTHER PTHR30429 1 265 1.1E-134 T 22-04-2016 IPR004872 Lipoprotein NlpA family TOLA_RS01320 647b7f3d7a9e9ecfdb345362ffb85060 265 Pfam PF03180 NLPA lipoprotein 29 265 1.2E-97 T 22-04-2016 IPR004872 Lipoprotein NlpA family TOLA_RS01320 647b7f3d7a9e9ecfdb345362ffb85060 265 SUPERFAMILY SSF53850 29 265 5.78E-80 T 22-04-2016 TOLA_RS01320 647b7f3d7a9e9ecfdb345362ffb85060 265 PIRSF PIRSF002854 1 265 9.4E-98 T 22-04-2016 IPR004872 Lipoprotein NlpA family TOLA_RS01320 647b7f3d7a9e9ecfdb345362ffb85060 265 Gene3D G3DSA:3.40.190.10 26 157 3.4E-56 T 22-04-2016 TOLA_RS01320 647b7f3d7a9e9ecfdb345362ffb85060 265 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 15 265 4.8E-121 T 22-04-2016 IPR004872 Lipoprotein NlpA family TOLA_RS01320 647b7f3d7a9e9ecfdb345362ffb85060 265 PANTHER PTHR30429:SF1 1 265 1.1E-134 T 22-04-2016 TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 Pfam PF00288 GHMP kinases N terminal domain 90 156 2.3E-13 T 22-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 PRINTS PR00958 Homoserine kinase signature 143 156 1.7E-30 T 22-04-2016 TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 PRINTS PR00958 Homoserine kinase signature 260 275 1.7E-30 T 22-04-2016 TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 PRINTS PR00958 Homoserine kinase signature 181 198 1.7E-30 T 22-04-2016 TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 PRINTS PR00958 Homoserine kinase signature 103 118 1.7E-30 T 22-04-2016 TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 PRINTS PR00958 Homoserine kinase signature 10 25 1.7E-30 T 22-04-2016 TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 PANTHER PTHR20861 1 317 2.6E-107 T 22-04-2016 TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 Gene3D G3DSA:3.30.230.10 2 168 3.6E-43 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 Gene3D G3DSA:3.30.70.890 174 304 5.7E-36 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 SUPERFAMILY SSF55060 178 293 1.76E-27 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 Pfam PF08544 GHMP kinases C terminal 230 287 2.8E-4 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 SUPERFAMILY SSF54211 3 191 9.11E-33 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 TIGRFAM TIGR00191 thrB: homoserine kinase 5 314 3.4E-96 T 22-04-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 Hamap MF_00384 Homoserine kinase [thrB]. 3 313 28.269 T 22-04-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 96 107 - T 22-04-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 PANTHER PTHR20861:SF1 1 317 2.6E-107 T 22-04-2016 TOLA_RS03215 509893a2f77112ee6599f5d599660798 318 PIRSF PIRSF000676 1 316 1.3E-76 T 22-04-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 Pfam PF02872 5'-nucleotidase, C-terminal domain 383 531 7.4E-24 T 22-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 Gene3D G3DSA:3.90.780.10 370 564 1.3E-31 T 22-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 PANTHER PTHR11575:SF7 332 564 2.6E-110 T 22-04-2016 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 PANTHER PTHR11575:SF7 7 292 2.6E-110 T 22-04-2016 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 SUPERFAMILY SSF55816 367 563 5.36E-38 T 22-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 SUPERFAMILY SSF56300 7 298 1.43E-68 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 PRINTS PR01607 Apyrase family signature 426 449 3.7E-14 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 PRINTS PR01607 Apyrase family signature 506 525 3.7E-14 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 PRINTS PR01607 Apyrase family signature 230 253 3.7E-14 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 PRINTS PR01607 Apyrase family signature 211 228 3.7E-14 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 PRINTS PR01607 Apyrase family signature 6 24 3.7E-14 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 Pfam PF00149 Calcineurin-like phosphoesterase 10 247 4.1E-9 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 PANTHER PTHR11575 332 564 2.6E-110 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 PANTHER PTHR11575 7 292 2.6E-110 T 22-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 TOLA_RS04135 2cd6c42ab066b1bec3198ff1ee7be5e4 576 Gene3D G3DSA:3.60.21.10 10 353 2.9E-71 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS04010 87772d8a446fe5b72a3fc45562015089 322 Gene3D G3DSA:3.30.470.20 231 287 2.6E-4 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS04010 87772d8a446fe5b72a3fc45562015089 322 SUPERFAMILY SSF56059 36 178 1.69E-16 T 22-04-2016 TOLA_RS04010 87772d8a446fe5b72a3fc45562015089 322 SUPERFAMILY SSF56059 234 280 1.69E-16 T 22-04-2016 TOLA_RS04010 87772d8a446fe5b72a3fc45562015089 322 TIGRFAM TIGR02291 rimK_rel_E_lig: alpha-L-glutamate ligase homolog 7 321 2.0E-144 T 22-04-2016 IPR011758 Alpha-L-glutamate ligase-related protein TOLA_RS04010 87772d8a446fe5b72a3fc45562015089 322 Pfam PF14397 Sugar-transfer associated ATP-grasp 23 297 8.7E-115 T 22-04-2016 TOLA_RS04010 87772d8a446fe5b72a3fc45562015089 322 Gene3D G3DSA:3.30.470.20 42 101 1.1E-4 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS05105 dbb135289f00e32eb34d29a1bea576f2 214 Gene3D G3DSA:3.40.50.300 1 208 1.4E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05105 dbb135289f00e32eb34d29a1bea576f2 214 SMART SM00382 26 212 3.2E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS05105 dbb135289f00e32eb34d29a1bea576f2 214 PANTHER PTHR24220 3 211 1.1E-78 T 22-04-2016 TOLA_RS05105 dbb135289f00e32eb34d29a1bea576f2 214 Pfam PF00005 ABC transporter 19 162 1.4E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS05105 dbb135289f00e32eb34d29a1bea576f2 214 PANTHER PTHR24220:SF485 3 211 1.1E-78 T 22-04-2016 TOLA_RS05105 dbb135289f00e32eb34d29a1bea576f2 214 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS05105 dbb135289f00e32eb34d29a1bea576f2 214 SUPERFAMILY SSF52540 1 205 1.46E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00060 e9a45a1a23b1d64acbe48ed1107edb7b 333 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 148 156 - T 22-04-2016 IPR000957 Sulphate/thiosulphate-binding, conserved site GO:0008271|GO:0008272|GO:0030288 TOLA_RS00060 e9a45a1a23b1d64acbe48ed1107edb7b 333 Pfam PF13531 Bacterial extracellular solute-binding protein 38 282 6.0E-45 T 22-04-2016 TOLA_RS00060 e9a45a1a23b1d64acbe48ed1107edb7b 333 PANTHER PTHR30368 5 333 4.1E-170 T 22-04-2016 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 TOLA_RS00060 e9a45a1a23b1d64acbe48ed1107edb7b 333 SUPERFAMILY SSF53850 23 330 4.35E-87 T 22-04-2016 TOLA_RS00060 e9a45a1a23b1d64acbe48ed1107edb7b 333 PANTHER PTHR30368:SF2 5 333 4.1E-170 T 22-04-2016 TOLA_RS00060 e9a45a1a23b1d64acbe48ed1107edb7b 333 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 15 328 5.7E-143 T 22-04-2016 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 TOLA_RS00060 e9a45a1a23b1d64acbe48ed1107edb7b 333 Gene3D G3DSA:3.40.190.10 117 280 1.1E-74 T 22-04-2016 TOLA_RS01440 414c88334c4f1bf1c26bcb47e5fcae99 113 SMART SM01259 26 99 3.3E-21 T 22-04-2016 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 TOLA_RS01440 414c88334c4f1bf1c26bcb47e5fcae99 113 PIRSF PIRSF028440 3 113 3.1E-44 T 22-04-2016 IPR014546 Uncharacterised conserved protein, lipid A biosynthesis TOLA_RS01440 414c88334c4f1bf1c26bcb47e5fcae99 113 ProDom PD339292 LIPID A SYNTHASE LIPID-A-DISACCHARIDE TRANSFERASE GLYCOSYLTRANSFERASE BIOSYNTHESIS N-TERMINAL BIOSYNTHESIS SYNTHESIS 21 104 3.0E-39 T 22-04-2016 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 TOLA_RS01440 414c88334c4f1bf1c26bcb47e5fcae99 113 Pfam PF07578 Lipid A Biosynthesis N-terminal domain 26 97 2.7E-20 T 22-04-2016 IPR011499 Lipid A biosynthesis GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 PANTHER PTHR11624 24 218 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 PANTHER PTHR11624 241 619 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 ProSitePatterns PS00802 Transketolase signature 2. 425 441 - T 22-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 PANTHER PTHR11624:SF20 24 218 0.0 T 22-04-2016 TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 PANTHER PTHR11624:SF20 241 619 0.0 T 22-04-2016 TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 11 282 5.2E-123 T 22-04-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 SUPERFAMILY SSF52922 491 619 4.06E-31 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 SUPERFAMILY SSF52518 243 381 7.81E-79 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 SUPERFAMILY SSF52518 7 199 7.81E-79 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 ProSitePatterns PS00801 Transketolase signature 1. 36 55 - T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 10 620 46.077 T 22-04-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 11 620 1.9E-298 T 22-04-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 Pfam PF02780 Transketolase, C-terminal domain 495 611 2.0E-24 T 22-04-2016 IPR033248 Transketolase, C-terminal domain TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 Gene3D G3DSA:3.40.50.920 496 619 1.5E-34 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 Gene3D G3DSA:3.40.50.970 335 495 1.4E-37 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 SUPERFAMILY SSF52518 316 504 1.39E-59 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 SMART SM00861 319 483 2.2E-66 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 Gene3D G3DSA:3.40.50.970 26 201 5.8E-78 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 Gene3D G3DSA:3.40.50.970 242 334 5.8E-78 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS12755 4ff7670a41d1fd833507cee610606ee8 620 Pfam PF02779 Transketolase, pyrimidine binding domain 319 478 5.6E-40 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS01690 08ac1ff9cdd463205ce3151b01c0d1d9 353 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 21 350 4.7E-112 T 22-04-2016 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 TOLA_RS01690 08ac1ff9cdd463205ce3151b01c0d1d9 353 PANTHER PTHR30106:SF2 20 353 4.2E-115 T 22-04-2016 TOLA_RS01690 08ac1ff9cdd463205ce3151b01c0d1d9 353 Pfam PF03601 Conserved hypothetical protein 698 21 332 1.6E-100 T 22-04-2016 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 TOLA_RS01690 08ac1ff9cdd463205ce3151b01c0d1d9 353 PANTHER PTHR30106 20 353 4.2E-115 T 22-04-2016 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 TOLA_RS07905 02fdf250988f1cb232392d507bae640d 339 Pfam PF13358 DDE superfamily endonuclease 176 312 1.2E-26 T 22-04-2016 TOLA_RS07905 02fdf250988f1cb232392d507bae640d 339 Pfam PF13565 Homeodomain-like domain 55 135 3.0E-10 T 22-04-2016 TOLA_RS07905 02fdf250988f1cb232392d507bae640d 339 SUPERFAMILY SSF46689 17 139 7.53E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09575 02fdf250988f1cb232392d507bae640d 339 Pfam PF13358 DDE superfamily endonuclease 176 312 1.2E-26 T 22-04-2016 TOLA_RS09575 02fdf250988f1cb232392d507bae640d 339 Pfam PF13565 Homeodomain-like domain 55 135 3.0E-10 T 22-04-2016 TOLA_RS09575 02fdf250988f1cb232392d507bae640d 339 SUPERFAMILY SSF46689 17 139 7.53E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS05430 02fdf250988f1cb232392d507bae640d 339 Pfam PF13358 DDE superfamily endonuclease 176 312 1.2E-26 T 22-04-2016 TOLA_RS05430 02fdf250988f1cb232392d507bae640d 339 Pfam PF13565 Homeodomain-like domain 55 135 3.0E-10 T 22-04-2016 TOLA_RS05430 02fdf250988f1cb232392d507bae640d 339 SUPERFAMILY SSF46689 17 139 7.53E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS03470 c8b257b360e46cddd8beecc067161195 257 Gene3D G3DSA:3.40.50.300 1 227 2.8E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03470 c8b257b360e46cddd8beecc067161195 257 SMART SM00382 26 213 2.6E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS03470 c8b257b360e46cddd8beecc067161195 257 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS03470 c8b257b360e46cddd8beecc067161195 257 PANTHER PTHR24220:SF471 3 250 2.0E-141 T 22-04-2016 TOLA_RS03470 c8b257b360e46cddd8beecc067161195 257 Pfam PF00005 ABC transporter 18 164 3.5E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS03470 c8b257b360e46cddd8beecc067161195 257 SUPERFAMILY SSF52540 2 226 8.52E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03470 c8b257b360e46cddd8beecc067161195 257 PANTHER PTHR24220 3 250 2.0E-141 T 22-04-2016 TOLA_RS07205 c096aa5e480386513bc62a2d1f2894ac 422 SUPERFAMILY SSF81901 254 367 4.01E-12 T 22-04-2016 TOLA_RS07205 c096aa5e480386513bc62a2d1f2894ac 422 Gene3D G3DSA:1.25.40.10 255 383 4.9E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS07205 c096aa5e480386513bc62a2d1f2894ac 422 Pfam PF08238 Sel1 repeat 260 292 2.4E-4 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS07205 c096aa5e480386513bc62a2d1f2894ac 422 Pfam PF08238 Sel1 repeat 293 329 0.26 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS07205 c096aa5e480386513bc62a2d1f2894ac 422 SMART SM00671 259 291 6.4 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS07205 c096aa5e480386513bc62a2d1f2894ac 422 SMART SM00671 293 329 13.0 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS07205 c096aa5e480386513bc62a2d1f2894ac 422 SMART SM00671 330 365 70.0 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 SMART SM00257 486 529 1.1E-13 T 22-04-2016 IPR018392 LysM domain TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 Pfam PF01476 LysM domain 487 529 9.0E-12 T 22-04-2016 IPR018392 LysM domain TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 Gene3D G3DSA:3.40.630.40 382 458 1.0E-57 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 Gene3D G3DSA:3.40.630.40 233 330 1.0E-57 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 PANTHER PTHR30404:SF1 3 97 1.1E-111 T 22-04-2016 TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 SUPERFAMILY SSF54106 485 529 2.88E-9 T 22-04-2016 IPR018392 LysM domain TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 PANTHER PTHR30404:SF1 222 484 1.1E-111 T 22-04-2016 TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 SUPERFAMILY SSF53187 381 457 9.1E-52 T 22-04-2016 TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 SUPERFAMILY SSF53187 233 329 9.1E-52 T 22-04-2016 TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 SMART SM00646 295 454 3.4E-56 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 PANTHER PTHR30404 115 184 1.1E-111 T 22-04-2016 TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 PANTHER PTHR30404 3 97 1.1E-111 T 22-04-2016 TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 235 454 2.0E-48 T 22-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 Gene3D G3DSA:3.10.350.10 486 529 2.7E-14 T 22-04-2016 IPR018392 LysM domain TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 PANTHER PTHR30404 222 484 1.1E-111 T 22-04-2016 TOLA_RS12140 9882f6243e1a686c81ba6cf710364aa0 531 PANTHER PTHR30404:SF1 115 184 1.1E-111 T 22-04-2016 TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 Pfam PF00381 PTS HPr component phosphorylation site 286 366 9.6E-25 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 SUPERFAMILY SSF55804 149 277 5.76E-14 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 47 63 - T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 Gene3D G3DSA:3.40.930.10 148 279 2.0E-12 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 PANTHER PTHR30181:SF3 2 374 2.0E-120 T 22-04-2016 TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 295 302 - T 22-04-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 Gene3D G3DSA:3.30.1340.10 285 372 2.1E-31 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 286 366 3.9E-24 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 140 2.8E-30 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 190 276 7.0E-5 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 Gene3D G3DSA:3.40.930.10 4 142 8.6E-40 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 SUPERFAMILY SSF55594 285 373 1.03E-25 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 PRINTS PR00107 Phosphocarrier protein signature 295 311 4.9E-18 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 PRINTS PR00107 Phosphocarrier protein signature 338 355 4.9E-18 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 PRINTS PR00107 Phosphocarrier protein signature 323 338 4.9E-18 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 324 339 - T 22-04-2016 IPR002114 Phosphotransferase system, HPr serine phosphorylation site TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 SUPERFAMILY SSF55804 4 141 2.88E-37 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 TOLA_RS01520 740fa2dda24bc9491cd02f62eda68164 377 PANTHER PTHR30181 2 374 2.0E-120 T 22-04-2016 TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 SMART SM00382 348 521 9.7E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 SMART SM00382 31 236 2.3E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 SUPERFAMILY SSF52540 11 243 3.58E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 PANTHER PTHR19211:SF7 1 555 0.0 T 22-04-2016 TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 Pfam PF12848 ABC transporter 230 303 1.1E-11 T 22-04-2016 IPR032781 ABC-transporter extension domain TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 Gene3D G3DSA:3.40.50.300 141 287 2.7E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 Gene3D G3DSA:3.40.50.300 10 105 2.7E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 PANTHER PTHR19211 1 555 0.0 T 22-04-2016 TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 SUPERFAMILY SSF52540 303 523 3.84E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 Pfam PF00005 ABC transporter 340 473 4.3E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 Pfam PF00005 ABC transporter 22 191 1.4E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 553 2.5E-296 T 22-04-2016 IPR022374 ABC transporter, ATP-binding protein, ChvD TOLA_RS02820 1e6c57395b399e156879a27de3f3ed52 555 Gene3D G3DSA:3.40.50.300 322 532 8.2E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13070 4b5cd2b7bb18dfab886834cc3fb834ca 403 PIRSF PIRSF004810 4 403 2.0E-127 T 22-04-2016 IPR014047 Chromate transporter, long chain TOLA_RS13070 4b5cd2b7bb18dfab886834cc3fb834ca 403 TIGRFAM TIGR00937 2A51: chromate efflux transporter 23 395 2.5E-100 T 22-04-2016 IPR014047 Chromate transporter, long chain TOLA_RS13070 4b5cd2b7bb18dfab886834cc3fb834ca 403 PANTHER PTHR33567:SF3 8 397 5.3E-133 T 22-04-2016 TOLA_RS13070 4b5cd2b7bb18dfab886834cc3fb834ca 403 Pfam PF02417 Chromate transporter 17 182 2.6E-34 T 22-04-2016 IPR003370 Chromate transporter GO:0015109|GO:0015703 TOLA_RS13070 4b5cd2b7bb18dfab886834cc3fb834ca 403 Pfam PF02417 Chromate transporter 233 398 5.8E-39 T 22-04-2016 IPR003370 Chromate transporter GO:0015109|GO:0015703 TOLA_RS13070 4b5cd2b7bb18dfab886834cc3fb834ca 403 PANTHER PTHR33567 8 397 5.3E-133 T 22-04-2016 TOLA_RS05880 69aff755abd59cee6fc5b06186e95ec5 448 Pfam PF00990 Diguanylate cyclase, GGDEF domain 328 408 1.6E-5 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 148 155 - T 22-04-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 150 1.1E-60 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 SUPERFAMILY SSF55347 149 312 4.37E-78 T 22-04-2016 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 Gene3D G3DSA:3.30.360.10 159 314 7.9E-85 T 22-04-2016 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 SMART SM00846 3 150 2.0E-97 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 SUPERFAMILY SSF51735 3 166 5.27E-69 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 2.7E-46 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 144 162 2.7E-46 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 171 187 2.7E-46 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 2.7E-46 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 2.7E-46 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 155 312 1.3E-70 T 22-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 2.0E-135 T 22-04-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 PANTHER PTHR10836 1 331 1.5E-242 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 Gene3D G3DSA:3.40.50.720 1 158 7.7E-80 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS13730 c7ebf8ffcf72193ca27373134c815ff4 331 PIRSF PIRSF000149 1 331 4.8E-136 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS16405 6ef44fc56ec3ae6f7acc777431754aab 190 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 13 138 4.5E-18 T 22-04-2016 IPR013362 Pilus modification type IV, PilV TOLA_RS16405 6ef44fc56ec3ae6f7acc777431754aab 190 Pfam PF13633 Prokaryotic N-terminal methylation site 13 39 4.4E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS16405 6ef44fc56ec3ae6f7acc777431754aab 190 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 14 34 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS16405 6ef44fc56ec3ae6f7acc777431754aab 190 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 35 1.5E-5 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 SUPERFAMILY SSF52374 4 158 2.06E-42 T 22-04-2016 TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 60 4.0E-16 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 2.1E-46 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 2.1E-46 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 2.1E-46 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 2.1E-46 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 2.1E-46 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 Pfam PF01467 Cytidylyltransferase-like 6 134 6.4E-16 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 PANTHER PTHR21342 1 157 9.8E-70 T 22-04-2016 TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 Gene3D G3DSA:3.40.50.620 2 161 1.2E-52 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 PANTHER PTHR21342:SF1 1 157 9.8E-70 T 22-04-2016 TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 5 157 9.3E-56 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 TOLA_RS00685 b85f03c913a5c921ac4e4a2ba0ffab54 164 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 33.303 T 22-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 103 115 - T 22-04-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 SMART SM00929 88 128 6.5E-16 T 22-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 SUPERFAMILY SSF50692 816 889 4.29E-9 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 SUPERFAMILY SSF53706 219 688 2.27E-82 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 150 160 - T 22-04-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 655 2.2E-195 T 22-04-2016 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 Gene3D G3DSA:3.40.50.740 285 340 3.3E-34 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 Gene3D G3DSA:3.40.50.740 504 687 3.3E-34 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 Gene3D G3DSA:2.40.40.20 819 889 3.9E-6 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 PANTHER PTHR11615:SF134 736 907 0.0 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 PANTHER PTHR11615:SF134 496 689 0.0 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 PANTHER PTHR11615:SF134 364 430 0.0 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 PANTHER PTHR11615:SF134 3 320 0.0 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 PANTHER PTHR11615 736 907 0.0 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 PANTHER PTHR11615 496 689 0.0 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 PANTHER PTHR11615 364 430 0.0 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 PANTHER PTHR11615 3 320 0.0 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 Gene3D G3DSA:2.20.25.90 228 274 4.3E-13 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 22-04-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 Gene3D G3DSA:3.30.70.20 198 227 1.7E-4 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 Gene3D G3DSA:3.30.70.20 147 157 1.7E-4 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 SMART SM00926 221 275 3.9E-10 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 SUPERFAMILY SSF54292 1 77 1.33E-18 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 78 3.9E-10 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 SUPERFAMILY SSF54862 81 210 5.86E-32 T 22-04-2016 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 Gene3D G3DSA:3.10.20.30 3 85 2.3E-9 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 Pfam PF00384 Molybdopterin oxidoreductase 552 637 1.9E-10 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 221 274 7.6E-10 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 TOLA_RS13460 80cd20d79b975f04bcdda995fa98c959 908 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 88 125 2.4E-13 T 22-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 TOLA_RS04740 d57221fac3a970d4bc3979653cdd45f3 626 PANTHER PTHR10342 237 574 9.4E-52 T 22-04-2016 TOLA_RS04740 d57221fac3a970d4bc3979653cdd45f3 626 PANTHER PTHR10342 617 624 9.4E-52 T 22-04-2016 TOLA_RS04740 d57221fac3a970d4bc3979653cdd45f3 626 Gene3D G3DSA:3.40.720.10 266 558 1.0E-32 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 TOLA_RS04740 d57221fac3a970d4bc3979653cdd45f3 626 PIRSF PIRSF004950 10 625 1.9E-194 T 22-04-2016 IPR012159 Inner membrane protein YejM TOLA_RS04740 d57221fac3a970d4bc3979653cdd45f3 626 Pfam PF00884 Sulfatase 281 539 3.4E-24 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 TOLA_RS04740 d57221fac3a970d4bc3979653cdd45f3 626 SUPERFAMILY SSF53649 263 580 1.83E-43 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 TOLA_RS04740 d57221fac3a970d4bc3979653cdd45f3 626 Pfam PF11893 Domain of unknown function (DUF3413) 12 257 4.4E-95 T 22-04-2016 IPR024588 Inner membrane protein YejM, N-terminal TOLA_RS04740 d57221fac3a970d4bc3979653cdd45f3 626 PANTHER PTHR10342:SF215 237 574 9.4E-52 T 22-04-2016 TOLA_RS04740 d57221fac3a970d4bc3979653cdd45f3 626 PANTHER PTHR10342:SF215 617 624 9.4E-52 T 22-04-2016 TOLA_RS09075 be7ab1760ea6b1e71df600467042dcc9 335 PANTHER PTHR11732 1 326 1.5E-134 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta TOLA_RS09075 be7ab1760ea6b1e71df600467042dcc9 335 Gene3D G3DSA:3.20.20.100 1 327 2.3E-106 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS09075 be7ab1760ea6b1e71df600467042dcc9 335 Pfam PF00248 Aldo/keto reductase family 16 315 7.3E-72 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS09075 be7ab1760ea6b1e71df600467042dcc9 335 PANTHER PTHR11732:SF225 1 326 1.5E-134 T 22-04-2016 TOLA_RS09075 be7ab1760ea6b1e71df600467042dcc9 335 SUPERFAMILY SSF51430 1 319 1.18E-94 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS07820 ef32f8ede73c77bf6adfbbb44253cee6 463 Gene3D G3DSA:1.10.220.70 54 140 1.2E-40 T 22-04-2016 TOLA_RS07820 ef32f8ede73c77bf6adfbbb44253cee6 463 Gene3D G3DSA:3.20.20.70 141 442 1.1E-159 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS07820 ef32f8ede73c77bf6adfbbb44253cee6 463 Gene3D G3DSA:2.30.170.30 1 53 3.3E-27 T 22-04-2016 TOLA_RS07820 ef32f8ede73c77bf6adfbbb44253cee6 463 PANTHER PTHR39329:SF1 1 459 2.0E-276 T 22-04-2016 TOLA_RS07820 ef32f8ede73c77bf6adfbbb44253cee6 463 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 11 444 4.9E-220 T 22-04-2016 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 TOLA_RS07820 ef32f8ede73c77bf6adfbbb44253cee6 463 PIRSF PIRSF018788 1 458 1.4E-236 T 22-04-2016 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 TOLA_RS07820 ef32f8ede73c77bf6adfbbb44253cee6 463 PANTHER PTHR39329 1 459 2.0E-276 T 22-04-2016 TOLA_RS00945 79b01ffbaa8d22894172805c4de25f54 266 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 259 1.4E-63 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS00945 79b01ffbaa8d22894172805c4de25f54 266 PANTHER PTHR10000:SF20 1 265 3.0E-94 T 22-04-2016 TOLA_RS00945 79b01ffbaa8d22894172805c4de25f54 266 Gene3D G3DSA:3.30.1240.10 82 175 4.8E-20 T 22-04-2016 TOLA_RS00945 79b01ffbaa8d22894172805c4de25f54 266 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 22-04-2016 IPR000150 Cof protein GO:0016787 TOLA_RS00945 79b01ffbaa8d22894172805c4de25f54 266 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 230 3.1E-32 T 22-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 TOLA_RS00945 79b01ffbaa8d22894172805c4de25f54 266 SUPERFAMILY SSF56784 1 264 1.73E-69 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS00945 79b01ffbaa8d22894172805c4de25f54 266 ProSitePatterns PS01229 Hypothetical cof family signature 2. 211 233 - T 22-04-2016 TOLA_RS00945 79b01ffbaa8d22894172805c4de25f54 266 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 259 7.1E-63 T 22-04-2016 IPR000150 Cof protein GO:0016787 TOLA_RS00945 79b01ffbaa8d22894172805c4de25f54 266 PANTHER PTHR10000 1 265 3.0E-94 T 22-04-2016 TOLA_RS00945 79b01ffbaa8d22894172805c4de25f54 266 Gene3D G3DSA:3.40.50.1000 176 264 1.1E-55 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS00945 79b01ffbaa8d22894172805c4de25f54 266 Gene3D G3DSA:3.40.50.1000 1 72 1.1E-55 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 SUPERFAMILY SSF51161 314 419 2.8E-19 T 22-04-2016 IPR011004 Trimeric LpxA-like TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 Pfam PF00483 Nucleotidyl transferase 21 295 1.9E-65 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 PANTHER PTHR22572:SF10 275 402 1.5E-169 T 22-04-2016 TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 PANTHER PTHR22572:SF10 20 258 1.5E-169 T 22-04-2016 TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 112 120 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 PANTHER PTHR22572 275 402 1.5E-169 T 22-04-2016 TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 PANTHER PTHR22572 20 258 1.5E-169 T 22-04-2016 TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 16 427 51.759 T 22-04-2016 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 210 220 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 19 401 7.1E-154 T 22-04-2016 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 25 44 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 SUPERFAMILY SSF53448 348 364 9.15E-75 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 SUPERFAMILY SSF53448 18 298 9.15E-75 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 Gene3D G3DSA:3.90.550.10 20 305 1.5E-75 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS11275 cba4f663a3533e647fda02410ba3a9a8 431 Gene3D G3DSA:3.90.550.10 348 391 1.5E-75 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS02460 5feec7d23508196791e7217be9bfd12f 192 Pfam PF04542 Sigma-70 region 2 27 94 1.0E-17 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS02460 5feec7d23508196791e7217be9bfd12f 192 SUPERFAMILY SSF88659 130 187 5.61E-14 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS02460 5feec7d23508196791e7217be9bfd12f 192 Gene3D G3DSA:1.10.10.10 125 188 2.3E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02460 5feec7d23508196791e7217be9bfd12f 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 184 6.6E-29 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS02460 5feec7d23508196791e7217be9bfd12f 192 PANTHER PTHR30173 2 192 2.7E-49 T 22-04-2016 TOLA_RS02460 5feec7d23508196791e7217be9bfd12f 192 SUPERFAMILY SSF88946 11 108 3.45E-22 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS02460 5feec7d23508196791e7217be9bfd12f 192 PANTHER PTHR30173:SF31 2 192 2.7E-49 T 22-04-2016 TOLA_RS02460 5feec7d23508196791e7217be9bfd12f 192 Gene3D G3DSA:1.10.1740.10 12 108 1.1E-20 T 22-04-2016 TOLA_RS02460 5feec7d23508196791e7217be9bfd12f 192 Pfam PF04545 Sigma-70, region 4 135 183 2.3E-13 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15780 f67976334dee40fb6481e7cc65a608c2 349 PANTHER PTHR11219 10 231 1.0E-16 T 22-04-2016 TOLA_RS15780 f67976334dee40fb6481e7cc65a608c2 349 PANTHER PTHR11219:SF46 10 231 1.0E-16 T 22-04-2016 TOLA_RS15780 f67976334dee40fb6481e7cc65a608c2 349 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 132 207 1.5E-21 T 22-04-2016 IPR022385 Rhs repeat-associated core GO:0097264 TOLA_RS06375 f61d0fb899e8bb0efdb14ec7006d5af8 368 Pfam PF01259 SAICAR synthetase 22 295 3.0E-48 T 22-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 TOLA_RS06375 f61d0fb899e8bb0efdb14ec7006d5af8 368 Gene3D G3DSA:3.30.200.20 13 135 2.3E-32 T 22-04-2016 TOLA_RS06375 f61d0fb899e8bb0efdb14ec7006d5af8 368 PANTHER PTHR11609 39 368 5.5E-69 T 22-04-2016 TOLA_RS06375 f61d0fb899e8bb0efdb14ec7006d5af8 368 Gene3D G3DSA:3.30.470.20 136 281 2.0E-39 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS06375 f61d0fb899e8bb0efdb14ec7006d5af8 368 PANTHER PTHR11609:SF1 39 368 5.5E-69 T 22-04-2016 TOLA_RS06375 f61d0fb899e8bb0efdb14ec7006d5af8 368 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 19 342 21.086 T 22-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 TOLA_RS06375 f61d0fb899e8bb0efdb14ec7006d5af8 368 SUPERFAMILY SSF56104 14 344 1.24E-66 T 22-04-2016 TOLA_RS06375 f61d0fb899e8bb0efdb14ec7006d5af8 368 TIGRFAM TIGR02735 purC_vibrio: phosphoribosylaminoimidazole-succinocarboxamide synthase 2 366 3.5E-204 T 22-04-2016 IPR014106 Phosphoribosylaminoimidazole-succinocarboxamide synthase, Vibrio-type GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 Gene3D G3DSA:3.30.70.1430 48 148 1.9E-18 T 22-04-2016 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 SUPERFAMILY SSF82866 821 1051 7.72E-41 T 22-04-2016 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 PANTHER PTHR32063:SF16 9 1052 0.0 T 22-04-2016 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 SUPERFAMILY SSF82693 47 137 1.45E-19 T 22-04-2016 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 SUPERFAMILY SSF82714 193 275 1.57E-14 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 SUPERFAMILY SSF82693 571 685 7.85E-15 T 22-04-2016 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 SUPERFAMILY SSF82866 303 504 1.96E-41 T 22-04-2016 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 SUPERFAMILY SSF82714 735 819 1.7E-9 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 Gene3D G3DSA:1.20.1640.10 298 511 1.1E-49 T 22-04-2016 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 Gene3D G3DSA:1.10.3850.10 826 1051 1.6E-70 T 22-04-2016 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 Pfam PF00873 AcrB/AcrD/AcrF family 14 1047 2.6E-162 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 Gene3D G3DSA:3.30.70.1430 576 684 1.2E-14 T 22-04-2016 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 SUPERFAMILY SSF82693 279 336 8.2E-11 T 22-04-2016 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 SUPERFAMILY SSF82693 150 191 8.2E-11 T 22-04-2016 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 PANTHER PTHR32063 9 1052 0.0 T 22-04-2016 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 PRINTS PR00702 Acriflavin resistance protein family signature 45 63 6.4E-26 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 PRINTS PR00702 Acriflavin resistance protein family signature 17 41 6.4E-26 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 PRINTS PR00702 Acriflavin resistance protein family signature 451 474 6.4E-26 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 PRINTS PR00702 Acriflavin resistance protein family signature 398 422 6.4E-26 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 PRINTS PR00702 Acriflavin resistance protein family signature 344 367 6.4E-26 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 PRINTS PR00702 Acriflavin resistance protein family signature 476 499 6.4E-26 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 Gene3D G3DSA:3.30.2090.10 734 820 7.8E-10 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS13065 f98953aaae1c4899c23de92be49666eb 1053 Gene3D G3DSA:3.30.2090.10 192 274 1.5E-15 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS08315 5c4ebf50c0919484e6c43d31c2ef2a11 239 SUPERFAMILY SSF161098 21 233 9.29E-38 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08315 5c4ebf50c0919484e6c43d31c2ef2a11 239 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 233 1.9E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08315 5c4ebf50c0919484e6c43d31c2ef2a11 239 PANTHER PTHR30133 13 238 8.0E-73 T 22-04-2016 TOLA_RS08315 5c4ebf50c0919484e6c43d31c2ef2a11 239 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 20 126 1.8E-15 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 TOLA_RS08315 5c4ebf50c0919484e6c43d31c2ef2a11 239 Gene3D G3DSA:1.10.3720.10 20 233 1.4E-37 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00655 4cdec45e659d3871d61e6950ec6409b5 195 PANTHER PTHR13256 1 193 5.8E-32 T 22-04-2016 TOLA_RS00655 4cdec45e659d3871d61e6950ec6409b5 195 PANTHER PTHR13256:SF28 1 193 5.8E-32 T 22-04-2016 TOLA_RS00655 4cdec45e659d3871d61e6950ec6409b5 195 Pfam PF13302 Acetyltransferase (GNAT) domain 6 150 1.5E-21 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS00655 4cdec45e659d3871d61e6950ec6409b5 195 SUPERFAMILY SSF55729 2 174 4.75E-36 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS00655 4cdec45e659d3871d61e6950ec6409b5 195 Gene3D G3DSA:3.40.630.30 2 173 1.4E-37 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS11950 f43049f0527d4b254d48765214769db7 294 Gene3D G3DSA:1.10.10.10 1 80 2.6E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11950 f43049f0527d4b254d48765214769db7 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.0E-10 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS11950 f43049f0527d4b254d48765214769db7 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.0E-10 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS11950 f43049f0527d4b254d48765214769db7 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.0E-10 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS11950 f43049f0527d4b254d48765214769db7 294 Gene3D G3DSA:3.40.190.10 168 259 2.2E-15 T 22-04-2016 TOLA_RS11950 f43049f0527d4b254d48765214769db7 294 SUPERFAMILY SSF53850 88 291 4.53E-29 T 22-04-2016 TOLA_RS11950 f43049f0527d4b254d48765214769db7 294 PANTHER PTHR30346:SF0 1 294 6.3E-63 T 22-04-2016 TOLA_RS11950 f43049f0527d4b254d48765214769db7 294 Gene3D G3DSA:3.40.190.10 88 167 4.7E-11 T 22-04-2016 TOLA_RS11950 f43049f0527d4b254d48765214769db7 294 Pfam PF03466 LysR substrate binding domain 88 289 1.4E-28 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS11950 f43049f0527d4b254d48765214769db7 294 SUPERFAMILY SSF46785 1 83 1.44E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11950 f43049f0527d4b254d48765214769db7 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 9.1E-21 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS11950 f43049f0527d4b254d48765214769db7 294 PANTHER PTHR30346 1 294 6.3E-63 T 22-04-2016 TOLA_RS02155 65240245874472650c48591c95632a57 309 SUPERFAMILY SSF53850 90 297 1.81E-46 T 22-04-2016 TOLA_RS02155 65240245874472650c48591c95632a57 309 PANTHER PTHR30537 5 295 2.0E-111 T 22-04-2016 TOLA_RS02155 65240245874472650c48591c95632a57 309 Gene3D G3DSA:3.40.190.10 89 165 4.3E-5 T 22-04-2016 TOLA_RS02155 65240245874472650c48591c95632a57 309 Gene3D G3DSA:3.40.190.10 166 261 3.2E-20 T 22-04-2016 TOLA_RS02155 65240245874472650c48591c95632a57 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 3.1E-17 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS02155 65240245874472650c48591c95632a57 309 Pfam PF03466 LysR substrate binding domain 89 292 6.1E-45 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS02155 65240245874472650c48591c95632a57 309 PANTHER PTHR30537:SF5 5 295 2.0E-111 T 22-04-2016 TOLA_RS02155 65240245874472650c48591c95632a57 309 SUPERFAMILY SSF46785 6 87 1.45E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02155 65240245874472650c48591c95632a57 309 Gene3D G3DSA:1.10.10.10 5 85 6.9E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02155 65240245874472650c48591c95632a57 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.9E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS02155 65240245874472650c48591c95632a57 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.9E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS02155 65240245874472650c48591c95632a57 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.9E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 Gene3D G3DSA:3.40.50.720 3 257 3.4E-66 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 Pfam PF00106 short chain dehydrogenase 3 196 5.5E-50 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 SUPERFAMILY SSF51735 3 257 6.18E-67 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 PANTHER PTHR24322:SF625 153 185 4.4E-40 T 22-04-2016 TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 PANTHER PTHR24322:SF625 7 137 4.4E-40 T 22-04-2016 TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 PANTHER PTHR24322 153 185 4.4E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 PANTHER PTHR24322 7 137 4.4E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.5E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.5E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.5E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.5E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 9.1E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 9.1E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01300 4eb43052e903690f897c635fccea6657 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 9.1E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 Gene3D G3DSA:3.40.50.720 3 257 3.4E-66 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 Pfam PF00106 short chain dehydrogenase 3 196 5.5E-50 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 SUPERFAMILY SSF51735 3 257 6.18E-67 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 PANTHER PTHR24322:SF625 153 185 4.4E-40 T 22-04-2016 TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 PANTHER PTHR24322:SF625 7 137 4.4E-40 T 22-04-2016 TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 PANTHER PTHR24322 153 185 4.4E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 PANTHER PTHR24322 7 137 4.4E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.5E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.5E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.5E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.5E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-22 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 9.1E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 9.1E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09510 4eb43052e903690f897c635fccea6657 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 9.1E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 338 359 5.2E-56 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 150 169 5.2E-56 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 497 510 5.2E-56 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 483 497 5.2E-56 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 465 483 5.2E-56 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 PRINTS PR00662 Glucose-6-phosphate isomerase signature 261 279 5.2E-56 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 265 278 - T 22-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 Gene3D G3DSA:1.10.1390.10 507 547 3.9E-22 T 22-04-2016 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 PANTHER PTHR11469 1 549 0.0 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 Gene3D G3DSA:3.40.50.10490 8 98 1.5E-146 T 22-04-2016 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 Gene3D G3DSA:3.40.50.10490 293 506 1.5E-146 T 22-04-2016 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 Gene3D G3DSA:3.40.50.10490 99 291 9.4E-89 T 22-04-2016 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 PANTHER PTHR11469:SF11 1 549 0.0 T 22-04-2016 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 SUPERFAMILY SSF53697 5 547 1.39E-223 T 22-04-2016 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 Pfam PF00342 Phosphoglucose isomerase 52 541 8.3E-254 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 497 514 - T 22-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS01480 dc08d90b38092f975b116d574e71d5cf 549 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 46 524 42.519 T 22-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Gene3D G3DSA:2.40.50.100 688 765 1.5E-30 T 22-04-2016 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 PANTHER PTHR20856 1007 1101 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 PANTHER PTHR20856 716 903 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Pfam PF04561 RNA polymerase Rpb2, domain 2 125 195 1.4E-6 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Pfam PF04561 RNA polymerase Rpb2, domain 2 322 427 6.6E-15 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Gene3D G3DSA:2.30.150.10 565 629 2.5E-27 T 22-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 SUPERFAMILY SSF64484 1012 1313 0.0 T 22-04-2016 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 SUPERFAMILY SSF64484 316 912 0.0 T 22-04-2016 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 SUPERFAMILY SSF64484 2 199 0.0 T 22-04-2016 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 PANTHER PTHR20856:SF20 1007 1101 0.0 T 22-04-2016 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 PANTHER PTHR20856:SF20 1155 1315 0.0 T 22-04-2016 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 PANTHER PTHR20856:SF20 716 903 0.0 T 22-04-2016 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Gene3D G3DSA:3.90.1110.10 126 203 9.9E-66 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Gene3D G3DSA:3.90.1110.10 319 417 9.9E-66 T 22-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 PANTHER PTHR20856:SF20 313 698 0.0 T 22-04-2016 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Pfam PF00562 RNA polymerase Rpb2, domain 6 690 1237 5.3E-157 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 PANTHER PTHR20856 313 698 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Pfam PF04560 RNA polymerase Rpb2, domain 7 1239 1313 3.8E-27 T 22-04-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1036 1048 - T 22-04-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 1 1312 0.0 T 22-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Pfam PF04565 RNA polymerase Rpb2, domain 3 486 553 1.9E-30 T 22-04-2016 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Gene3D G3DSA:2.40.270.10 1033 1215 1.3E-86 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Gene3D G3DSA:2.40.270.10 766 793 1.3E-86 T 22-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 1 1315 12.168 T 22-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Gene3D G3DSA:3.90.1100.10 632 686 1.2E-144 T 22-04-2016 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Gene3D G3DSA:3.90.1100.10 2 124 1.2E-144 T 22-04-2016 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Gene3D G3DSA:3.90.1100.10 418 564 1.2E-144 T 22-04-2016 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Pfam PF04563 RNA polymerase beta subunit 2 473 2.9E-52 T 22-04-2016 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Pfam PF10385 RNA polymerase beta subunit external 1 domain 564 629 3.4E-23 T 22-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Gene3D G3DSA:2.40.50.150 801 910 1.1E-56 T 22-04-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 Gene3D G3DSA:2.40.50.150 1018 1032 1.1E-56 T 22-04-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 PANTHER PTHR20856:SF20 1 204 0.0 T 22-04-2016 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 PANTHER PTHR20856 1155 1315 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14250 3a40c241461161e1f0b02b70cbda6401 1315 PANTHER PTHR20856 1 204 0.0 T 22-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS09915 fe8770ea904b79a5ba7a8992e604c225 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.4E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09915 fe8770ea904b79a5ba7a8992e604c225 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 3.4E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09915 fe8770ea904b79a5ba7a8992e604c225 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 3.4E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09915 fe8770ea904b79a5ba7a8992e604c225 268 Pfam PF00106 short chain dehydrogenase 7 192 6.2E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09915 fe8770ea904b79a5ba7a8992e604c225 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.4E-16 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09915 fe8770ea904b79a5ba7a8992e604c225 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.4E-16 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09915 fe8770ea904b79a5ba7a8992e604c225 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.4E-16 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09915 fe8770ea904b79a5ba7a8992e604c225 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.4E-16 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09915 fe8770ea904b79a5ba7a8992e604c225 268 PANTHER PTHR24322 150 175 9.6E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09915 fe8770ea904b79a5ba7a8992e604c225 268 PANTHER PTHR24322 10 134 9.6E-40 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09915 fe8770ea904b79a5ba7a8992e604c225 268 SUPERFAMILY SSF51735 1 260 3.81E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09915 fe8770ea904b79a5ba7a8992e604c225 268 Gene3D G3DSA:3.40.50.720 8 250 9.8E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS07465 7616726cbc9bc3757c59eb4fa056a137 378 Pfam PF13808 DDE_Tnp_1-associated 7 94 5.1E-30 T 22-04-2016 IPR032806 H repeat-associated protein, N-terminal TOLA_RS07465 7616726cbc9bc3757c59eb4fa056a137 378 PANTHER PTHR30298 6 376 2.3E-120 T 22-04-2016 TOLA_RS07465 7616726cbc9bc3757c59eb4fa056a137 378 Pfam PF01609 Transposase DDE domain 103 343 2.2E-23 T 22-04-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TOLA_RS12890 7c77f4534e9225f276faff967ad48696 292 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 284 6.5E-105 T 22-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 TOLA_RS12890 7c77f4534e9225f276faff967ad48696 292 PANTHER PTHR18895 16 290 2.2E-147 T 22-04-2016 TOLA_RS12890 7c77f4534e9225f276faff967ad48696 292 PIRSF PIRSF000401 1 292 3.5E-92 T 22-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 TOLA_RS12890 7c77f4534e9225f276faff967ad48696 292 PANTHER PTHR18895:SF69 16 290 2.2E-147 T 22-04-2016 TOLA_RS12890 7c77f4534e9225f276faff967ad48696 292 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 290 32.485 T 22-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 TOLA_RS12890 7c77f4534e9225f276faff967ad48696 292 SUPERFAMILY SSF53335 50 270 2.69E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS12890 7c77f4534e9225f276faff967ad48696 292 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 290 2.0E-97 T 22-04-2016 TOLA_RS12890 7c77f4534e9225f276faff967ad48696 292 Gene3D G3DSA:3.40.50.150 96 284 1.6E-42 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS15875 8a5fd5f82b9f9039b03cf9107fcf10b7 616 Pfam PF00920 Dehydratase family 34 607 7.3E-220 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS15875 8a5fd5f82b9f9039b03cf9107fcf10b7 616 SUPERFAMILY SSF52016 421 611 2.12E-60 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel TOLA_RS15875 8a5fd5f82b9f9039b03cf9107fcf10b7 616 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS15875 8a5fd5f82b9f9039b03cf9107fcf10b7 616 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 509 520 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS15875 8a5fd5f82b9f9039b03cf9107fcf10b7 616 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 610 6.2E-264 T 22-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS15875 8a5fd5f82b9f9039b03cf9107fcf10b7 616 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 610 45.53 T 22-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS15875 8a5fd5f82b9f9039b03cf9107fcf10b7 616 PANTHER PTHR21000 1 371 0.0 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS15875 8a5fd5f82b9f9039b03cf9107fcf10b7 616 PANTHER PTHR21000 406 616 0.0 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS15875 8a5fd5f82b9f9039b03cf9107fcf10b7 616 SUPERFAMILY SSF143975 3 420 6.67E-136 T 22-04-2016 TOLA_RS15875 8a5fd5f82b9f9039b03cf9107fcf10b7 616 PANTHER PTHR21000:SF11 1 371 0.0 T 22-04-2016 TOLA_RS15875 8a5fd5f82b9f9039b03cf9107fcf10b7 616 PANTHER PTHR21000:SF11 406 616 0.0 T 22-04-2016 TOLA_RS06610 1281481931b5f0179c2d5e4b7abc77d7 530 PANTHER PTHR37417:SF2 10 500 9.3E-202 T 22-04-2016 TOLA_RS06610 1281481931b5f0179c2d5e4b7abc77d7 530 Pfam PF06100 MCRA family 10 499 5.1E-199 T 22-04-2016 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 UniPathway: UPA00199 TOLA_RS06610 1281481931b5f0179c2d5e4b7abc77d7 530 SUPERFAMILY SSF51905 13 243 9.91E-12 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS06610 1281481931b5f0179c2d5e4b7abc77d7 530 Gene3D G3DSA:3.50.50.60 2 62 2.0E-9 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS06610 1281481931b5f0179c2d5e4b7abc77d7 530 Gene3D G3DSA:3.50.50.60 206 254 2.0E-9 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS06610 1281481931b5f0179c2d5e4b7abc77d7 530 PANTHER PTHR37417 10 500 9.3E-202 T 22-04-2016 TOLA_RS10140 65f7a5854b0a50df124d38bbfce53cf5 297 SUPERFAMILY SSF53850 93 294 1.94E-37 T 22-04-2016 TOLA_RS10140 65f7a5854b0a50df124d38bbfce53cf5 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.5E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10140 65f7a5854b0a50df124d38bbfce53cf5 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.5E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10140 65f7a5854b0a50df124d38bbfce53cf5 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.5E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10140 65f7a5854b0a50df124d38bbfce53cf5 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 3.7E-21 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10140 65f7a5854b0a50df124d38bbfce53cf5 297 Gene3D G3DSA:1.10.10.10 6 84 1.1E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10140 65f7a5854b0a50df124d38bbfce53cf5 297 Gene3D G3DSA:3.40.190.10 181 264 7.3E-9 T 22-04-2016 TOLA_RS10140 65f7a5854b0a50df124d38bbfce53cf5 297 PANTHER PTHR30537:SF1 1 293 3.7E-145 T 22-04-2016 TOLA_RS10140 65f7a5854b0a50df124d38bbfce53cf5 297 Pfam PF03466 LysR substrate binding domain 93 293 1.1E-35 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS10140 65f7a5854b0a50df124d38bbfce53cf5 297 Gene3D G3DSA:3.40.190.10 94 180 2.9E-18 T 22-04-2016 TOLA_RS10140 65f7a5854b0a50df124d38bbfce53cf5 297 SUPERFAMILY SSF46785 6 113 5.8E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10140 65f7a5854b0a50df124d38bbfce53cf5 297 PANTHER PTHR30537 1 293 3.7E-145 T 22-04-2016 TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 9.9E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 9.9E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 9.9E-6 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 SUPERFAMILY SSF51735 4 249 1.77E-54 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 Pfam PF00106 short chain dehydrogenase 5 187 4.2E-45 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.2E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.2E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.2E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.2E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.2E-18 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 PANTHER PTHR24322 146 178 3.0E-53 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 PANTHER PTHR24322 7 130 3.0E-53 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 PANTHER PTHR24322:SF463 146 178 3.0E-53 T 22-04-2016 TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 PANTHER PTHR24322:SF463 7 130 3.0E-53 T 22-04-2016 TOLA_RS04660 1f51ab75dce6754cbaf52e7553155d49 275 Gene3D G3DSA:3.40.50.720 4 271 7.8E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 PIRSF PIRSF036388 1 431 7.5E-187 T 22-04-2016 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 PRINTS PR00481 Cytosol aminopeptidase signature 214 235 4.8E-44 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 PRINTS PR00481 Cytosol aminopeptidase signature 273 293 4.8E-44 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 PRINTS PR00481 Cytosol aminopeptidase signature 251 272 4.8E-44 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 PRINTS PR00481 Cytosol aminopeptidase signature 192 209 4.8E-44 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 PRINTS PR00481 Cytosol aminopeptidase signature 301 316 4.8E-44 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 Gene3D G3DSA:3.40.630.10 97 430 1.1E-109 T 22-04-2016 TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 PANTHER PTHR11963 45 429 1.9E-190 T 22-04-2016 TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 PANTHER PTHR11963:SF20 45 429 1.9E-190 T 22-04-2016 TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 277 284 - T 22-04-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 SUPERFAMILY SSF53187 105 429 2.35E-96 T 22-04-2016 TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 111 423 2.8E-96 T 22-04-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TOLA_RS10235 8cc02056854b04031a67b2710d13e8ee 431 Pfam PF12404 Peptidase 5 83 7.0E-29 T 22-04-2016 IPR008330 Peptidase M17, peptidase B GO:0004177|GO:0005737|GO:0006508|GO:0008235|GO:0030145 KEGG: 00480+3.4.11.23 TOLA_RS03950 b924946860e977eeacff28bc5aa9a9d4 507 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 466 8.6E-158 T 22-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 TOLA_RS03950 b924946860e977eeacff28bc5aa9a9d4 507 PIRSF PIRSF000485 1 483 1.5E-161 T 22-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 TOLA_RS03950 b924946860e977eeacff28bc5aa9a9d4 507 Pfam PF00156 Phosphoribosyl transferase domain 283 394 1.4E-8 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 TOLA_RS03950 b924946860e977eeacff28bc5aa9a9d4 507 Pfam PF13522 Glutamine amidotransferase domain 64 195 5.4E-15 T 22-04-2016 TOLA_RS03950 b924946860e977eeacff28bc5aa9a9d4 507 PANTHER PTHR11907:SF0 1 480 2.5E-246 T 22-04-2016 TOLA_RS03950 b924946860e977eeacff28bc5aa9a9d4 507 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 468 43.481 T 22-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 TOLA_RS03950 b924946860e977eeacff28bc5aa9a9d4 507 SUPERFAMILY SSF56235 2 259 2.23E-70 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS03950 b924946860e977eeacff28bc5aa9a9d4 507 Gene3D G3DSA:3.60.20.10 2 260 4.5E-62 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS03950 b924946860e977eeacff28bc5aa9a9d4 507 Gene3D G3DSA:3.40.50.2020 280 443 1.9E-44 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS03950 b924946860e977eeacff28bc5aa9a9d4 507 SUPERFAMILY SSF53271 252 485 2.36E-71 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS03950 b924946860e977eeacff28bc5aa9a9d4 507 PANTHER PTHR11907 1 480 2.5E-246 T 22-04-2016 TOLA_RS06010 3575d1f856f19a4ff01468fa9ffe2709 429 Gene3D G3DSA:1.20.1250.20 230 419 1.0E-13 T 22-04-2016 TOLA_RS06010 3575d1f856f19a4ff01468fa9ffe2709 429 Pfam PF07690 Major Facilitator Superfamily 22 380 1.1E-45 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS06010 3575d1f856f19a4ff01468fa9ffe2709 429 Gene3D G3DSA:1.20.1250.20 13 212 4.8E-39 T 22-04-2016 TOLA_RS06010 3575d1f856f19a4ff01468fa9ffe2709 429 PANTHER PTHR11662:SF3 8 414 4.5E-144 T 22-04-2016 TOLA_RS06010 3575d1f856f19a4ff01468fa9ffe2709 429 SUPERFAMILY SSF103473 9 415 1.06E-71 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS06010 3575d1f856f19a4ff01468fa9ffe2709 429 PANTHER PTHR11662 8 414 4.5E-144 T 22-04-2016 TOLA_RS03075 42a8ce9967a76c16d3e8ed4516d8726d 356 SUPERFAMILY SSF56935 29 186 6.87E-6 T 22-04-2016 TOLA_RS03075 42a8ce9967a76c16d3e8ed4516d8726d 356 SUPERFAMILY SSF56935 234 356 6.87E-6 T 22-04-2016 TOLA_RS03075 42a8ce9967a76c16d3e8ed4516d8726d 356 Pfam PF16966 Porin-like glycoporin RafY 36 356 2.0E-109 T 22-04-2016 IPR016963 Glycoporin RafY TOLA_RS11885 a26d724be97363db59089c25997d858b 178 PANTHER PTHR19384:SF77 1 129 2.1E-31 T 22-04-2016 TOLA_RS11885 a26d724be97363db59089c25997d858b 178 PANTHER PTHR19384:SF77 149 176 2.1E-31 T 22-04-2016 TOLA_RS11885 a26d724be97363db59089c25997d858b 178 PANTHER PTHR19384 1 129 2.1E-31 T 22-04-2016 TOLA_RS11885 a26d724be97363db59089c25997d858b 178 PANTHER PTHR19384 149 176 2.1E-31 T 22-04-2016 TOLA_RS11885 a26d724be97363db59089c25997d858b 178 Pfam PF00258 Flavodoxin 6 168 8.9E-30 T 22-04-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 TOLA_RS11885 a26d724be97363db59089c25997d858b 178 Gene3D G3DSA:3.40.50.360 1 176 1.3E-53 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS11885 a26d724be97363db59089c25997d858b 178 TIGRFAM TIGR01752 flav_long: flavodoxin 3 176 2.9E-63 T 22-04-2016 IPR010086 Flavodoxin, long chain GO:0010181 TOLA_RS11885 a26d724be97363db59089c25997d858b 178 PIRSF PIRSF038996 1 178 8.4E-61 T 22-04-2016 IPR010086 Flavodoxin, long chain GO:0010181 TOLA_RS11885 a26d724be97363db59089c25997d858b 178 SUPERFAMILY SSF52218 3 176 4.97E-41 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS11885 a26d724be97363db59089c25997d858b 178 PRINTS PR00369 Flavodoxin signature 52 63 3.0E-5 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TOLA_RS11885 a26d724be97363db59089c25997d858b 178 PRINTS PR00369 Flavodoxin signature 89 99 3.0E-5 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TOLA_RS11885 a26d724be97363db59089c25997d858b 178 PRINTS PR00369 Flavodoxin signature 5 18 3.0E-5 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TOLA_RS11885 a26d724be97363db59089c25997d858b 178 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 22-04-2016 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 49 214 5.4E-63 T 22-04-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 PRINTS PR00132 Glycosyl hydrolase family 2 signature 526 541 2.7E-35 T 22-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 PRINTS PR00132 Glycosyl hydrolase family 2 signature 370 388 2.7E-35 T 22-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 PRINTS PR00132 Glycosyl hydrolase family 2 signature 442 457 2.7E-35 T 22-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 PRINTS PR00132 Glycosyl hydrolase family 2 signature 339 353 2.7E-35 T 22-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 PRINTS PR00132 Glycosyl hydrolase family 2 signature 142 157 2.7E-35 T 22-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 Gene3D G3DSA:3.20.20.80 330 618 1.5E-112 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 Gene3D G3DSA:2.60.120.260 3 203 1.4E-82 T 22-04-2016 IPR008979 Galactose-binding domain-like TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 Gene3D G3DSA:2.60.40.320 204 328 1.6E-30 T 22-04-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 Gene3D G3DSA:2.70.98.10 740 1022 3.5E-90 T 22-04-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 PANTHER PTHR10066 589 1021 0.0 T 22-04-2016 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 PANTHER PTHR10066 1 571 0.0 T 22-04-2016 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 SUPERFAMILY SSF74650 740 1022 5.96E-92 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 SUPERFAMILY SSF49785 10 214 8.36E-67 T 22-04-2016 IPR008979 Galactose-binding domain-like TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 PANTHER PTHR10066:SF72 589 1021 0.0 T 22-04-2016 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 PANTHER PTHR10066:SF72 1 571 0.0 T 22-04-2016 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 380 405 - T 22-04-2016 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 Gene3D G3DSA:2.60.40.320 620 725 1.8E-26 T 22-04-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 Pfam PF16353 Domain of unknown function(DUF4981) 634 722 1.7E-16 T 22-04-2016 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 SUPERFAMILY SSF49303 216 328 8.92E-23 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 330 623 3.0E-108 T 22-04-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 Pfam PF02929 Beta galactosidase small chain 755 1021 1.3E-66 T 22-04-2016 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 Hamap MF_01687 Beta-galactosidase [lacZ]. 1 1024 16.991 T 22-04-2016 IPR023933 Glycoside hydrolase, family 2, beta-galactosidase GO:0016798 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 SUPERFAMILY SSF49303 616 724 1.73E-26 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 Pfam PF00703 Glycosyl hydrolases family 2 217 328 5.7E-11 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 SMART SM01038 749 1022 1.4E-109 T 22-04-2016 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14930 2346688e4247537688729460c86fa2dc 1025 SUPERFAMILY SSF51445 330 619 7.72E-101 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 149 1082 0.0 T 22-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 Gene3D G3DSA:3.30.2060.10 133 205 4.4E-14 T 22-04-2016 TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 SMART SM00490 826 910 3.7E-18 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 SUPERFAMILY SSF52540 352 467 1.01E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 PANTHER PTHR14025:SF21 385 1150 0.0 T 22-04-2016 TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 SUPERFAMILY SSF52540 525 783 7.01E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 SUPERFAMILY SSF52540 11 346 1.17E-99 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 SMART SM01058 481 576 1.9E-48 T 22-04-2016 IPR003711 CarD-like/TRCF domain TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 Pfam PF00270 DEAD/DEAH box helicase 605 765 2.5E-19 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 SUPERFAMILY SSF141259 472 548 6.8E-23 T 22-04-2016 IPR003711 CarD-like/TRCF domain TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 26 1104 29.299 T 22-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 Gene3D G3DSA:3.40.50.300 588 786 9.1E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 Gene3D G3DSA:3.40.50.300 789 963 7.3E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 Pfam PF02559 CarD-like/TRCF domain 482 575 7.5E-26 T 22-04-2016 IPR003711 CarD-like/TRCF domain TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 SUPERFAMILY SSF52540 782 990 5.22E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 PANTHER PTHR14025 385 1150 0.0 T 22-04-2016 TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 SMART SM00982 1008 1108 1.3E-50 T 22-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 Pfam PF00271 Helicase conserved C-terminal domain 804 909 4.6E-17 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 SMART SM00487 600 790 5.9E-34 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 Pfam PF03461 TRCF domain 1009 1100 3.0E-29 T 22-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TOLA_RS11375 e7f1a2f979777b4edf123c09adeaa68e 1150 SUPERFAMILY SSF143517 994 1146 2.75E-44 T 22-04-2016 TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 Gene3D G3DSA:3.40.50.300 113 290 8.0E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 PANTHER PTHR30050:SF2 1 98 2.8E-235 T 22-04-2016 TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 PANTHER PTHR30050:SF2 124 461 2.8E-235 T 22-04-2016 TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 SMART SM00382 158 289 4.0E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 SUPERFAMILY SSF48295 358 460 1.05E-37 T 22-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 Gene3D G3DSA:1.10.8.60 292 359 2.2E-30 T 22-04-2016 TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 PANTHER PTHR30050 1 98 2.8E-235 T 22-04-2016 TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 ProSitePatterns PS01008 DnaA protein signature. 419 438 - T 22-04-2016 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 Gene3D G3DSA:1.10.1750.10 360 460 2.0E-42 T 22-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 Pfam PF00308 Bacterial dnaA protein 127 342 7.5E-99 T 22-04-2016 IPR013317 Chromosomal replication initiator protein DnaA TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 6 459 4.7E-184 T 22-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 SMART SM00760 369 438 2.2E-45 T 22-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 SUPERFAMILY SSF52540 127 337 1.49E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 159 179 5.1E-54 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 419 438 5.1E-54 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 257 284 5.1E-54 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 191 205 5.1E-54 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 223 237 5.1E-54 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 PANTHER PTHR30050 124 461 2.8E-235 T 22-04-2016 TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 3 460 34.243 T 22-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 Pfam PF11638 DnaA N-terminal domain 4 64 4.5E-16 T 22-04-2016 IPR024633 DnaA N-terminal domain TOLA_RS00005 6211cc430d129e7a7a4ea354e1d73667 461 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 370 438 1.6E-32 T 22-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TOLA_RS05630 7e2a946cbaa91d46e8171dd142f242a3 227 PIRSF PIRSF006755 1 227 7.9E-72 T 22-04-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 TOLA_RS05630 7e2a946cbaa91d46e8171dd142f242a3 227 PANTHER PTHR21343:SF13 1 227 8.0E-92 T 22-04-2016 TOLA_RS05630 7e2a946cbaa91d46e8171dd142f242a3 227 SUPERFAMILY SSF52540 1 212 2.29E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05630 7e2a946cbaa91d46e8171dd142f242a3 227 PANTHER PTHR21343 1 227 8.0E-92 T 22-04-2016 TOLA_RS05630 7e2a946cbaa91d46e8171dd142f242a3 227 Pfam PF13500 AAA domain 3 210 1.4E-33 T 22-04-2016 TOLA_RS05630 7e2a946cbaa91d46e8171dd142f242a3 227 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 178 8.5E-45 T 22-04-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 TOLA_RS05630 7e2a946cbaa91d46e8171dd142f242a3 227 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 220 28.366 T 22-04-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 TOLA_RS05630 7e2a946cbaa91d46e8171dd142f242a3 227 Gene3D G3DSA:3.40.50.300 1 218 3.9E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02680 7bd52e7211960a656e7a46fb05c35444 308 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 305 3.5E-119 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS02680 7bd52e7211960a656e7a46fb05c35444 308 Pfam PF01795 MraW methylase family 2 305 4.7E-114 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS02680 7bd52e7211960a656e7a46fb05c35444 308 PANTHER PTHR11265:SF0 1 308 9.2E-147 T 22-04-2016 TOLA_RS02680 7bd52e7211960a656e7a46fb05c35444 308 PANTHER PTHR11265 1 308 9.2E-147 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS02680 7bd52e7211960a656e7a46fb05c35444 308 SUPERFAMILY SSF53335 3 109 1.28E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS02680 7bd52e7211960a656e7a46fb05c35444 308 SUPERFAMILY SSF53335 209 306 1.28E-44 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS02680 7bd52e7211960a656e7a46fb05c35444 308 Gene3D G3DSA:3.40.50.150 3 106 2.8E-51 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS02680 7bd52e7211960a656e7a46fb05c35444 308 Gene3D G3DSA:3.40.50.150 212 306 2.8E-51 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS02680 7bd52e7211960a656e7a46fb05c35444 308 PIRSF PIRSF004486 1 307 1.2E-103 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS02680 7bd52e7211960a656e7a46fb05c35444 308 SUPERFAMILY SSF81799 110 209 9.42E-35 T 22-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS02680 7bd52e7211960a656e7a46fb05c35444 308 Gene3D G3DSA:1.10.150.170 108 211 1.0E-37 T 22-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS02680 7bd52e7211960a656e7a46fb05c35444 308 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 3 306 38.568 T 22-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS01825 ffff931899a242aa535593c80a7f61b0 89 Pfam PF02583 Metal-sensitive transcriptional repressor 8 85 1.9E-22 T 22-04-2016 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 TOLA_RS01825 ffff931899a242aa535593c80a7f61b0 89 PANTHER PTHR33677 1 89 4.5E-25 T 22-04-2016 TOLA_RS14575 67f2bae61a33c9a51379b7dc59ccf817 87 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 7 86 7.3E-26 T 22-04-2016 IPR009614 Toxin YoeB GO:0004519|GO:0006401 TOLA_RS14575 67f2bae61a33c9a51379b7dc59ccf817 87 SUPERFAMILY SSF143011 2 87 1.96E-17 T 22-04-2016 TOLA_RS14575 67f2bae61a33c9a51379b7dc59ccf817 87 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 23 86 1.7E-7 T 22-04-2016 IPR009614 Toxin YoeB GO:0004519|GO:0006401 TOLA_RS13145 63ca28c169caf6f8cb5a178b2236c298 521 Pfam PF08666 SAF domain 20 89 3.3E-8 T 22-04-2016 IPR013974 SAF domain TOLA_RS13145 63ca28c169caf6f8cb5a178b2236c298 521 TIGRFAM TIGR03248 galactar-dH20: galactarate dehydratase 13 521 1.5E-280 T 22-04-2016 IPR017654 Galactarate dehydratase GarD-like GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497|UniPathway: UPA00565 TOLA_RS13145 63ca28c169caf6f8cb5a178b2236c298 521 Hamap MF_02031 Galactarate dehydratase (L-threo-forming) [garD]. 1 521 75.797 T 22-04-2016 IPR032893 Galactarate dehydratase (L-threo-forming) GarD, Enterobacteriaceae GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497|UniPathway: UPA00565 TOLA_RS13145 63ca28c169caf6f8cb5a178b2236c298 521 PANTHER PTHR30536:SF1 1 521 0.0 T 22-04-2016 TOLA_RS13145 63ca28c169caf6f8cb5a178b2236c298 521 SMART SM00858 20 90 4.0E-8 T 22-04-2016 IPR013974 SAF domain TOLA_RS13145 63ca28c169caf6f8cb5a178b2236c298 521 PANTHER PTHR30536 1 521 0.0 T 22-04-2016 TOLA_RS13145 63ca28c169caf6f8cb5a178b2236c298 521 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 117 518 1.7E-145 T 22-04-2016 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 TOLA_RS05505 d94b0bcdc109a65148ee7ece41316a91 218 SUPERFAMILY SSF51391 8 208 3.14E-66 T 22-04-2016 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS05505 d94b0bcdc109a65148ee7ece41316a91 218 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 3 208 20.591 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS05505 d94b0bcdc109a65148ee7ece41316a91 218 PANTHER PTHR20857 4 216 3.0E-67 T 22-04-2016 TOLA_RS05505 d94b0bcdc109a65148ee7ece41316a91 218 PANTHER PTHR20857:SF15 4 216 3.0E-67 T 22-04-2016 TOLA_RS05505 d94b0bcdc109a65148ee7ece41316a91 218 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 21 203 2.7E-55 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS05505 d94b0bcdc109a65148ee7ece41316a91 218 Gene3D G3DSA:3.20.20.70 7 209 2.6E-69 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS05505 d94b0bcdc109a65148ee7ece41316a91 218 Pfam PF02581 Thiamine monophosphate synthase/TENI 21 190 4.3E-55 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 281 296 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 219 232 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 SUPERFAMILY SSF52540 194 428 8.87E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 SMART SM00382 215 358 1.5E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 PANTHER PTHR32071 141 518 8.4E-162 T 22-04-2016 TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 PANTHER PTHR32071:SF35 141 518 8.4E-162 T 22-04-2016 TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 Gene3D G3DSA:3.30.450.40 27 172 1.3E-17 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 Gene3D G3DSA:3.40.50.300 192 367 6.0E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 SUPERFAMILY SSF55781 27 172 2.01E-18 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 Pfam PF00158 Sigma-54 interaction domain 195 361 1.0E-70 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 Gene3D G3DSA:1.10.8.60 368 417 1.4E-15 T 22-04-2016 TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 SUPERFAMILY SSF46689 470 518 6.72E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 Pfam PF01590 GAF domain 24 160 2.9E-9 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 408 417 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 SMART SM00065 22 171 5.5E-12 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS14545 db05512536db0a1f4cff270d94cc4a6b 521 Gene3D G3DSA:1.10.10.60 418 518 8.4E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 Gene3D G3DSA:1.10.150.80 536 606 2.3E-24 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 SMART SM00956 413 516 2.9E-55 T 22-04-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 17 466 2.8E-175 T 22-04-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 SUPERFAMILY SSF52540 210 461 9.74E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 Pfam PF00570 HRDC domain 538 604 2.2E-25 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 SMART SM00490 252 333 5.1E-31 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 Gene3D G3DSA:1.10.10.10 347 517 8.0E-64 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 Pfam PF16124 RecQ zinc-binding 345 406 1.8E-17 T 22-04-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 Pfam PF09382 RQC domain 408 517 5.0E-40 T 22-04-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 PANTHER PTHR13710:SF81 16 609 8.6E-288 T 22-04-2016 TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 Gene3D G3DSA:3.40.50.300 16 203 1.5E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 SUPERFAMILY SSF52540 13 201 5.43E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 PANTHER PTHR13710 16 609 8.6E-288 T 22-04-2016 TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 17 607 3.0E-251 T 22-04-2016 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 SUPERFAMILY SSF47819 534 609 2.18E-25 T 22-04-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 Gene3D G3DSA:3.40.50.300 209 346 2.5E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 SMART SM00341 534 610 2.6E-19 T 22-04-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 Pfam PF00271 Helicase conserved C-terminal domain 229 333 1.0E-19 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 Pfam PF00270 DEAD/DEAH box helicase 30 187 1.5E-16 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS15290 5cde7954ed85146532f93f21e2ecd805 610 SMART SM00487 24 220 2.1E-29 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS13860 8de85e61db5d092e644483a06d65216a 84 PANTHER PTHR34404 2 73 1.5E-18 T 22-04-2016 TOLA_RS13860 8de85e61db5d092e644483a06d65216a 84 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 2.5E-22 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain TOLA_RS13860 8de85e61db5d092e644483a06d65216a 84 SMART SM00834 1 42 3.0E-18 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain TOLA_RS13860 8de85e61db5d092e644483a06d65216a 84 PANTHER PTHR34404:SF2 2 73 1.5E-18 T 22-04-2016 TOLA_RS13860 8de85e61db5d092e644483a06d65216a 84 Pfam PF09723 Zinc ribbon domain 1 40 3.5E-15 T 22-04-2016 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain TOLA_RS03135 76d3cbe8c0c7b53bf2df2d2a8e8897b6 433 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 10 411 5.5E-125 T 22-04-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 TOLA_RS03135 76d3cbe8c0c7b53bf2df2d2a8e8897b6 433 PANTHER PTHR30588:SF0 1 433 8.8E-179 T 22-04-2016 TOLA_RS03135 76d3cbe8c0c7b53bf2df2d2a8e8897b6 433 PANTHER PTHR30588 1 433 8.8E-179 T 22-04-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 TOLA_RS03135 76d3cbe8c0c7b53bf2df2d2a8e8897b6 433 Pfam PF05525 Branched-chain amino acid transport protein 4 422 1.2E-133 T 22-04-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 Gene3D G3DSA:3.40.50.620 11 227 2.3E-80 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 SUPERFAMILY SSF55174 298 397 1.58E-14 T 22-04-2016 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 Gene3D G3DSA:1.10.240.10 228 327 1.2E-37 T 22-04-2016 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 PANTHER PTHR11766:SF1 4 398 4.2E-222 T 22-04-2016 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 SUPERFAMILY SSF52374 8 316 1.39E-93 T 22-04-2016 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 211 223 1.6E-25 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 1.6E-25 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 178 200 1.6E-25 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 1.6E-25 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 2 398 46.893 T 22-04-2016 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 Gene3D G3DSA:3.10.290.10 328 398 1.8E-20 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 Pfam PF00579 tRNA synthetases class I (W and Y) 30 317 3.8E-74 T 22-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 5 398 8.4E-117 T 22-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 TOLA_RS03010 df3401701259f071990f98f1ed16353b 399 PANTHER PTHR11766 4 398 4.2E-222 T 22-04-2016 IPR024088 Tyrosine-tRNA ligase, bacterial-type GO:0004831 KEGG: 00970+6.1.1.1 TOLA_RS09295 0f09d5094a2dcd42d3209cba53f11431 493 Gene3D G3DSA:3.30.420.40 254 489 3.9E-72 T 22-04-2016 TOLA_RS09295 0f09d5094a2dcd42d3209cba53f11431 493 PANTHER PTHR10196 1 489 1.9E-182 T 22-04-2016 TOLA_RS09295 0f09d5094a2dcd42d3209cba53f11431 493 Gene3D G3DSA:3.30.420.40 3 251 3.0E-87 T 22-04-2016 TOLA_RS09295 0f09d5094a2dcd42d3209cba53f11431 493 SUPERFAMILY SSF53067 252 488 1.73E-63 T 22-04-2016 TOLA_RS09295 0f09d5094a2dcd42d3209cba53f11431 493 PIRSF PIRSF000538 3 492 1.3E-137 T 22-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 TOLA_RS09295 0f09d5094a2dcd42d3209cba53f11431 493 SUPERFAMILY SSF53067 5 251 2.5E-79 T 22-04-2016 TOLA_RS09295 0f09d5094a2dcd42d3209cba53f11431 493 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 250 9.0E-68 T 22-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TOLA_RS09295 0f09d5094a2dcd42d3209cba53f11431 493 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 445 6.3E-45 T 22-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TOLA_RS09295 0f09d5094a2dcd42d3209cba53f11431 493 PANTHER PTHR10196:SF9 1 489 1.9E-182 T 22-04-2016 TOLA_RS05250 66574f8bf09d267cb6fa1c50e00850c7 283 PANTHER PTHR30514:SF7 1 273 1.6E-176 T 22-04-2016 TOLA_RS05250 66574f8bf09d267cb6fa1c50e00850c7 283 PANTHER PTHR30514 1 273 1.6E-176 T 22-04-2016 TOLA_RS05250 66574f8bf09d267cb6fa1c50e00850c7 283 Gene3D G3DSA:1.10.10.10 1 80 1.3E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05250 66574f8bf09d267cb6fa1c50e00850c7 283 SUPERFAMILY SSF53697 92 277 1.01E-38 T 22-04-2016 TOLA_RS05250 66574f8bf09d267cb6fa1c50e00850c7 283 Gene3D G3DSA:3.40.50.10490 95 270 8.6E-37 T 22-04-2016 TOLA_RS05250 66574f8bf09d267cb6fa1c50e00850c7 283 Pfam PF01418 Helix-turn-helix domain, rpiR family 1 76 1.6E-28 T 22-04-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 TOLA_RS05250 66574f8bf09d267cb6fa1c50e00850c7 283 SUPERFAMILY SSF46689 1 80 1.97E-21 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS05250 66574f8bf09d267cb6fa1c50e00850c7 283 Pfam PF01380 SIS domain 124 252 1.1E-22 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 TOLA_RS11360 a1bec568455c326d2582f476a62c9f92 413 Pfam PF02687 FtsX-like permease family 274 404 1.4E-21 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 TOLA_RS11360 a1bec568455c326d2582f476a62c9f92 413 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 411 1.6E-144 T 22-04-2016 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 TOLA_RS11360 a1bec568455c326d2582f476a62c9f92 413 Pfam PF12704 MacB-like periplasmic core domain 28 231 1.4E-15 T 22-04-2016 IPR025857 MacB-like periplasmic core domain TOLA_RS11360 a1bec568455c326d2582f476a62c9f92 413 PANTHER PTHR30489:SF8 1 410 9.0E-89 T 22-04-2016 TOLA_RS11360 a1bec568455c326d2582f476a62c9f92 413 PANTHER PTHR30489 1 410 9.0E-89 T 22-04-2016 TOLA_RS00575 5ee9e65a63f463a20a17de85d6b1f52a 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 40 102 4.4E-22 T 22-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00575 5ee9e65a63f463a20a17de85d6b1f52a 105 Gene3D G3DSA:2.30.30.30 3 93 1.5E-22 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 TOLA_RS00575 5ee9e65a63f463a20a17de85d6b1f52a 105 SUPERFAMILY SSF50104 4 102 5.54E-33 T 22-04-2016 IPR008991 Translation protein SH3-like domain TOLA_RS00575 5ee9e65a63f463a20a17de85d6b1f52a 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 98 19.611 T 22-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00575 5ee9e65a63f463a20a17de85d6b1f52a 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 103 3.8E-38 T 22-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00575 5ee9e65a63f463a20a17de85d6b1f52a 105 PANTHER PTHR12903 4 102 3.1E-45 T 22-04-2016 TOLA_RS00575 5ee9e65a63f463a20a17de85d6b1f52a 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 8 25 - T 22-04-2016 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS13245 96c534be20e2d0ecf5e990c75fe8668b 245 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 3 244 43.502 T 22-04-2016 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB TOLA_RS13245 96c534be20e2d0ecf5e990c75fe8668b 245 Gene3D G3DSA:3.40.1280.10 90 244 5.0E-54 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TOLA_RS13245 96c534be20e2d0ecf5e990c75fe8668b 245 SMART SM00967 5 81 3.9E-19 T 22-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 TOLA_RS13245 96c534be20e2d0ecf5e990c75fe8668b 245 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 5 77 2.8E-18 T 22-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 TOLA_RS13245 96c534be20e2d0ecf5e990c75fe8668b 245 PANTHER PTHR12029 4 244 4.9E-81 T 22-04-2016 TOLA_RS13245 96c534be20e2d0ecf5e990c75fe8668b 245 SUPERFAMILY SSF75217 73 244 9.81E-49 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases TOLA_RS13245 96c534be20e2d0ecf5e990c75fe8668b 245 Pfam PF00588 SpoU rRNA Methylase family 97 237 1.7E-39 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TOLA_RS13245 96c534be20e2d0ecf5e990c75fe8668b 245 SUPERFAMILY SSF55315 3 76 6.83E-20 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like TOLA_RS13245 96c534be20e2d0ecf5e990c75fe8668b 245 Gene3D G3DSA:3.30.1330.30 2 76 3.5E-25 T 22-04-2016 IPR029064 50S ribosomal protein L30e-like TOLA_RS13245 96c534be20e2d0ecf5e990c75fe8668b 245 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 243 3.4E-84 T 22-04-2016 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 TOLA_RS00380 1d142390c5451261a60637c995e11d34 202 Gene3D G3DSA:1.10.150.240 25 71 4.7E-5 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 TOLA_RS00380 1d142390c5451261a60637c995e11d34 202 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 180 193 4.9E-5 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS00380 1d142390c5451261a60637c995e11d34 202 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 4.9E-5 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS00380 1d142390c5451261a60637c995e11d34 202 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 4.9E-5 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS00380 1d142390c5451261a60637c995e11d34 202 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 4.9E-5 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS00380 1d142390c5451261a60637c995e11d34 202 SUPERFAMILY SSF56784 10 192 7.97E-43 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS00380 1d142390c5451261a60637c995e11d34 202 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 10 191 2.5E-46 T 22-04-2016 IPR010976 Beta-phosphoglucomutase hydrolase TOLA_RS00380 1d142390c5451261a60637c995e11d34 202 PANTHER PTHR18901 1 192 1.8E-42 T 22-04-2016 TOLA_RS00380 1d142390c5451261a60637c995e11d34 202 Gene3D G3DSA:3.40.50.1000 7 24 4.5E-31 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS00380 1d142390c5451261a60637c995e11d34 202 Gene3D G3DSA:3.40.50.1000 96 192 4.5E-31 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS00380 1d142390c5451261a60637c995e11d34 202 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 142 189 3.3E-15 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS00380 1d142390c5451261a60637c995e11d34 202 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 189 1.5E-24 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS05795 ac748c6af9cf513e4026712ec30013a3 228 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 21 177 9.5E-36 T 22-04-2016 IPR003709 Peptidase M15B GO:0006508|GO:0008233 TOLA_RS05795 ac748c6af9cf513e4026712ec30013a3 228 SUPERFAMILY SSF55166 19 179 3.92E-20 T 22-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain TOLA_RS05795 ac748c6af9cf513e4026712ec30013a3 228 PANTHER PTHR34385 86 220 2.1E-43 T 22-04-2016 TOLA_RS05795 ac748c6af9cf513e4026712ec30013a3 228 PANTHER PTHR34385 23 66 2.1E-43 T 22-04-2016 TOLA_RS05795 ac748c6af9cf513e4026712ec30013a3 228 PANTHER PTHR34385:SF1 86 220 2.1E-43 T 22-04-2016 TOLA_RS05795 ac748c6af9cf513e4026712ec30013a3 228 PANTHER PTHR34385:SF1 23 66 2.1E-43 T 22-04-2016 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 PANTHER PTHR30511:SF4 1 357 4.9E-179 T 22-04-2016 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 SUPERFAMILY SSF50621 228 356 4.19E-46 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 Pfam PF00842 Alanine racemase, C-terminal domain 233 355 4.9E-40 T 22-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 SUPERFAMILY SSF51419 8 234 1.89E-67 T 22-04-2016 IPR029066 PLP-binding barrel TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 SMART SM01005 233 357 8.2E-67 T 22-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 PRINTS PR00992 Alanine racemase signature 26 42 1.4E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 PRINTS PR00992 Alanine racemase signature 287 304 1.4E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 PRINTS PR00992 Alanine racemase signature 249 264 1.4E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 PRINTS PR00992 Alanine racemase signature 155 166 1.4E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 PRINTS PR00992 Alanine racemase signature 266 281 1.4E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 PRINTS PR00992 Alanine racemase signature 339 352 1.4E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 PRINTS PR00992 Alanine racemase signature 120 132 1.4E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 PRINTS PR00992 Alanine racemase signature 60 78 1.4E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 PRINTS PR00992 Alanine racemase signature 192 219 1.4E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 Gene3D G3DSA:3.20.20.10 10 211 2.9E-69 T 22-04-2016 IPR029066 PLP-binding barrel TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 Gene3D G3DSA:2.40.37.10 212 356 7.9E-57 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 PANTHER PTHR30511 1 357 4.9E-179 T 22-04-2016 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 31 41 - T 22-04-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 TIGRFAM TIGR00492 alr: alanine racemase 5 357 1.5E-125 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 Hamap MF_01201 Alanine racemase. 1 357 34.473 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS02890 ab06fbf8ac4296cdeaa5181aa59ed08a 357 Pfam PF01168 Alanine racemase, N-terminal domain 8 219 4.4E-66 T 22-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS09035 406ed12bc8929dff72e89010d991f354 143 Pfam PF07883 Cupin domain 30 98 2.7E-18 T 22-04-2016 IPR013096 Cupin 2, conserved barrel TOLA_RS09035 406ed12bc8929dff72e89010d991f354 143 PANTHER PTHR36440:SF1 5 140 1.5E-22 T 22-04-2016 TOLA_RS09035 406ed12bc8929dff72e89010d991f354 143 PANTHER PTHR36440 5 140 1.5E-22 T 22-04-2016 TOLA_RS09035 406ed12bc8929dff72e89010d991f354 143 Gene3D G3DSA:2.60.120.10 6 137 2.0E-24 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS09035 406ed12bc8929dff72e89010d991f354 143 SUPERFAMILY SSF51182 18 122 6.74E-23 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 SMART SM00981 77 167 4.5E-21 T 22-04-2016 IPR004114 THUMP domain GO:0003723 TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 178 371 3.7E-70 T 22-04-2016 IPR020536 Thil, AANH domain GO:0004810 UniPathway: UPA00060 TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 485 216.666 T 22-04-2016 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 UniPathway: UPA00060 TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 Pfam PF02926 THUMP domain 29 163 1.9E-22 T 22-04-2016 IPR004114 THUMP domain GO:0003723 TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 SUPERFAMILY SSF52402 177 374 2.21E-39 T 22-04-2016 TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 Gene3D G3DSA:3.40.250.10 405 482 5.4E-11 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 PANTHER PTHR14911:SF15 3 419 8.8E-236 T 22-04-2016 TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 Gene3D G3DSA:3.40.50.620 175 335 7.2E-36 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 SUPERFAMILY SSF143437 1 175 5.58E-47 T 22-04-2016 TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 PANTHER PTHR14911 3 419 8.8E-236 T 22-04-2016 TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 377 3.4E-114 T 22-04-2016 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 UniPathway: UPA00060 TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 SUPERFAMILY SSF52821 407 483 6.29E-12 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS12740 3746c9db01e1d05c4d5f1c2374ba8262 485 TIGRFAM TIGR04271 ThiI_C_thiazole: thiazole biosynthesis domain 384 484 3.2E-41 T 22-04-2016 IPR026340 Thiazole biosynthesis domain GO:0052837 UniPathway: UPA00060 TOLA_RS00015 ab782ee03ae3707c99cc2ad47d9812d2 357 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 341 1.8E-34 T 22-04-2016 IPR003395 RecF/RecN/SMC, N-terminal TOLA_RS00015 ab782ee03ae3707c99cc2ad47d9812d2 357 Gene3D G3DSA:3.40.50.300 229 354 1.8E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00015 ab782ee03ae3707c99cc2ad47d9812d2 357 Gene3D G3DSA:3.40.50.300 1 170 1.8E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00015 ab782ee03ae3707c99cc2ad47d9812d2 357 SUPERFAMILY SSF52540 1 356 1.5E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00015 ab782ee03ae3707c99cc2ad47d9812d2 357 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 22-04-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 TOLA_RS00015 ab782ee03ae3707c99cc2ad47d9812d2 357 PANTHER PTHR32182 1 342 1.7E-55 T 22-04-2016 TOLA_RS00015 ab782ee03ae3707c99cc2ad47d9812d2 357 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 357 90.735 T 22-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TOLA_RS00015 ab782ee03ae3707c99cc2ad47d9812d2 357 ProSitePatterns PS00618 RecF protein signature 2. 297 315 - T 22-04-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 TOLA_RS00015 ab782ee03ae3707c99cc2ad47d9812d2 357 PANTHER PTHR32182:SF0 1 342 1.7E-55 T 22-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TOLA_RS00015 ab782ee03ae3707c99cc2ad47d9812d2 357 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 355 4.1E-111 T 22-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TOLA_RS14335 0828b9a0178d27036923780d91480254 510 PIRSF PIRSF000203 1 509 1.1E-266 T 22-04-2016 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2 TOLA_RS14335 0828b9a0178d27036923780d91480254 510 Gene3D G3DSA:3.40.50.1770 198 371 1.3E-44 T 22-04-2016 TOLA_RS14335 0828b9a0178d27036923780d91480254 510 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 170 195 - T 22-04-2016 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 TOLA_RS14335 0828b9a0178d27036923780d91480254 510 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 22-04-2016 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 TOLA_RS14335 0828b9a0178d27036923780d91480254 510 Gene3D G3DSA:3.40.50.1770 1 171 5.5E-67 T 22-04-2016 TOLA_RS14335 0828b9a0178d27036923780d91480254 510 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 426 509 3.8E-37 T 22-04-2016 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2 TOLA_RS14335 0828b9a0178d27036923780d91480254 510 SMART SM01003 4 137 7.9E-74 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TOLA_RS14335 0828b9a0178d27036923780d91480254 510 Gene3D G3DSA:3.40.50.720 172 197 5.1E-5 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14335 0828b9a0178d27036923780d91480254 510 TIGRFAM TIGR00561 pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit 2 510 3.3E-269 T 22-04-2016 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2 TOLA_RS14335 0828b9a0178d27036923780d91480254 510 SUPERFAMILY SSF52283 1 168 7.99E-55 T 22-04-2016 TOLA_RS14335 0828b9a0178d27036923780d91480254 510 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 369 8.4E-76 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TOLA_RS14335 0828b9a0178d27036923780d91480254 510 SMART SM01002 146 312 2.6E-82 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TOLA_RS14335 0828b9a0178d27036923780d91480254 510 PANTHER PTHR10160 1 509 0.0 T 22-04-2016 TOLA_RS14335 0828b9a0178d27036923780d91480254 510 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 1.8E-50 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TOLA_RS14335 0828b9a0178d27036923780d91480254 510 SUPERFAMILY SSF51735 138 318 1.54E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS15680 fb651bbd5dba266ed6f3f115251946e3 666 Pfam PF13559 Domain of unknown function (DUF4129) 595 654 1.5E-9 T 22-04-2016 IPR025403 Domain of unknown function DUF4129 TOLA_RS15680 fb651bbd5dba266ed6f3f115251946e3 666 SMART SM00460 413 483 2.6E-22 T 22-04-2016 IPR002931 Transglutaminase-like TOLA_RS15680 fb651bbd5dba266ed6f3f115251946e3 666 PANTHER PTHR33490 48 666 2.4E-77 T 22-04-2016 TOLA_RS15680 fb651bbd5dba266ed6f3f115251946e3 666 Pfam PF11992 Domain of unknown function (DUF3488) 16 335 1.5E-84 T 22-04-2016 IPR021878 Protein of unknown function DUF3488 TOLA_RS15680 fb651bbd5dba266ed6f3f115251946e3 666 PANTHER PTHR33490:SF4 48 666 2.4E-77 T 22-04-2016 TOLA_RS15680 fb651bbd5dba266ed6f3f115251946e3 666 Pfam PF01841 Transglutaminase-like superfamily 368 481 2.3E-24 T 22-04-2016 IPR002931 Transglutaminase-like TOLA_RS15680 fb651bbd5dba266ed6f3f115251946e3 666 SUPERFAMILY SSF54001 286 615 1.68E-61 T 22-04-2016 TOLA_RS15680 fb651bbd5dba266ed6f3f115251946e3 666 Gene3D G3DSA:3.90.260.10 307 608 7.6E-50 T 22-04-2016 IPR002931 Transglutaminase-like TOLA_RS02480 766fb43ed4996fdda60d66f5e0d6c9ef 364 Hamap MF_01841 Agmatine deiminase [aguA]. 8 363 57.356 T 22-04-2016 IPR017754 Agmatine deiminase GO:0009446|GO:0047632 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 TOLA_RS02480 766fb43ed4996fdda60d66f5e0d6c9ef 364 SUPERFAMILY SSF55909 5 363 7.14E-141 T 22-04-2016 TOLA_RS02480 766fb43ed4996fdda60d66f5e0d6c9ef 364 TIGRFAM TIGR03380 agmatine_aguA: agmatine deiminase 9 363 2.7E-173 T 22-04-2016 IPR017754 Agmatine deiminase GO:0009446|GO:0047632 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 TOLA_RS02480 766fb43ed4996fdda60d66f5e0d6c9ef 364 PANTHER PTHR31377:SF0 1 364 2.5E-182 T 22-04-2016 TOLA_RS02480 766fb43ed4996fdda60d66f5e0d6c9ef 364 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 17 362 2.0E-121 T 22-04-2016 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 TOLA_RS02480 766fb43ed4996fdda60d66f5e0d6c9ef 364 PANTHER PTHR31377 1 364 2.5E-182 T 22-04-2016 TOLA_RS02480 766fb43ed4996fdda60d66f5e0d6c9ef 364 Gene3D G3DSA:3.75.10.10 8 363 2.4E-145 T 22-04-2016 TOLA_RS08790 f516f9dbc0e43425c462939d08a4c722 140 Gene3D G3DSA:3.10.20.80 2 48 7.0E-20 T 22-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 TOLA_RS08790 f516f9dbc0e43425c462939d08a4c722 140 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 2 46 8.8E-17 T 22-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 TOLA_RS08790 f516f9dbc0e43425c462939d08a4c722 140 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 140 4.5E-60 T 22-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 TOLA_RS08790 f516f9dbc0e43425c462939d08a4c722 140 ProSitePatterns PS00938 Initiation factor 3 signature. 28 41 - T 22-04-2016 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 TOLA_RS08790 f516f9dbc0e43425c462939d08a4c722 140 Gene3D G3DSA:3.30.110.10 49 139 4.6E-41 T 22-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 TOLA_RS08790 f516f9dbc0e43425c462939d08a4c722 140 SUPERFAMILY SSF54364 2 48 2.62E-16 T 22-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 TOLA_RS08790 f516f9dbc0e43425c462939d08a4c722 140 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 53 138 8.5E-39 T 22-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 TOLA_RS08790 f516f9dbc0e43425c462939d08a4c722 140 SUPERFAMILY SSF55200 53 139 1.31E-34 T 22-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 TOLA_RS08790 f516f9dbc0e43425c462939d08a4c722 140 PANTHER PTHR10938 1 140 1.3E-55 T 22-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 TOLA_RS11280 a9553401096e4b0457e86ea37cbd8f0f 528 SMART SM00267 106 275 5.1E-12 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS11280 a9553401096e4b0457e86ea37cbd8f0f 528 SUPERFAMILY SSF141868 293 525 1.31E-41 T 22-04-2016 IPR001633 EAL domain TOLA_RS11280 a9553401096e4b0457e86ea37cbd8f0f 528 SUPERFAMILY SSF55073 122 273 1.1E-18 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS11280 a9553401096e4b0457e86ea37cbd8f0f 528 Gene3D G3DSA:3.20.20.450 288 525 2.0E-41 T 22-04-2016 IPR001633 EAL domain TOLA_RS11280 a9553401096e4b0457e86ea37cbd8f0f 528 PANTHER PTHR33121:SF10 289 526 1.8E-26 T 22-04-2016 TOLA_RS11280 a9553401096e4b0457e86ea37cbd8f0f 528 Pfam PF00990 Diguanylate cyclase, GGDEF domain 119 267 1.0E-18 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS11280 a9553401096e4b0457e86ea37cbd8f0f 528 Pfam PF00563 EAL domain 319 522 9.7E-42 T 22-04-2016 IPR001633 EAL domain TOLA_RS11280 a9553401096e4b0457e86ea37cbd8f0f 528 SMART SM00052 285 528 2.6E-15 T 22-04-2016 IPR001633 EAL domain TOLA_RS11280 a9553401096e4b0457e86ea37cbd8f0f 528 PANTHER PTHR33121 289 526 1.8E-26 T 22-04-2016 TOLA_RS11280 a9553401096e4b0457e86ea37cbd8f0f 528 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 113 268 2.6E-11 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS11280 a9553401096e4b0457e86ea37cbd8f0f 528 Gene3D G3DSA:3.30.70.270 119 277 3.2E-20 T 22-04-2016 TOLA_RS03235 71c37a4a03146beb2aa95e01f5ad8329 85 PANTHER PTHR33705 1 84 2.3E-36 T 22-04-2016 TOLA_RS03235 71c37a4a03146beb2aa95e01f5ad8329 85 Pfam PF00381 PTS HPr component phosphorylation site 3 82 1.1E-26 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS03235 71c37a4a03146beb2aa95e01f5ad8329 85 Gene3D G3DSA:3.30.1340.10 1 83 2.8E-32 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS03235 71c37a4a03146beb2aa95e01f5ad8329 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 22-04-2016 IPR002114 Phosphotransferase system, HPr serine phosphorylation site TOLA_RS03235 71c37a4a03146beb2aa95e01f5ad8329 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 2.6E-28 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS03235 71c37a4a03146beb2aa95e01f5ad8329 85 PANTHER PTHR33705:SF1 1 84 2.3E-36 T 22-04-2016 TOLA_RS03235 71c37a4a03146beb2aa95e01f5ad8329 85 SUPERFAMILY SSF55594 1 82 1.03E-26 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS03235 71c37a4a03146beb2aa95e01f5ad8329 85 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 22-04-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site TOLA_RS03235 71c37a4a03146beb2aa95e01f5ad8329 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 7.9E-20 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS03235 71c37a4a03146beb2aa95e01f5ad8329 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 7.9E-20 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS03235 71c37a4a03146beb2aa95e01f5ad8329 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 7.9E-20 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS07590 bf6808b2caf292456341dddf18a60ede 551 PANTHER PTHR24220 324 533 2.2E-100 T 22-04-2016 TOLA_RS07590 bf6808b2caf292456341dddf18a60ede 551 TIGRFAM TIGR01194 cyc_pep_trnsptr: cyclic peptide transporter 3 531 2.8E-110 T 22-04-2016 IPR005898 Cyclic peptide transporter GO:0005524|GO:0015197|GO:0015833|GO:0016021 TOLA_RS07590 bf6808b2caf292456341dddf18a60ede 551 SUPERFAMILY SSF52540 321 543 3.41E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07590 bf6808b2caf292456341dddf18a60ede 551 Gene3D G3DSA:1.20.1560.10 4 301 2.3E-16 T 22-04-2016 TOLA_RS07590 bf6808b2caf292456341dddf18a60ede 551 PANTHER PTHR24220:SF425 324 533 2.2E-100 T 22-04-2016 TOLA_RS07590 bf6808b2caf292456341dddf18a60ede 551 Gene3D G3DSA:3.40.50.300 322 542 2.1E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07590 bf6808b2caf292456341dddf18a60ede 551 SMART SM00382 352 530 1.4E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS07590 bf6808b2caf292456341dddf18a60ede 551 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS07590 bf6808b2caf292456341dddf18a60ede 551 SUPERFAMILY SSF90123 7 299 3.53E-22 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS07590 bf6808b2caf292456341dddf18a60ede 551 Pfam PF00005 ABC transporter 345 481 3.8E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 7 335 2.0E-165 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 Gene3D G3DSA:3.40.50.970 330 535 4.1E-77 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 ProSitePatterns PS00802 Transketolase signature 2. 469 485 - T 22-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 Gene3D G3DSA:3.40.50.970 6 323 2.8E-131 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 Pfam PF02779 Transketolase, pyrimidine binding domain 356 526 1.3E-45 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 SUPERFAMILY SSF52518 335 527 1.18E-65 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 PANTHER PTHR11624 1 305 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 PANTHER PTHR11624 338 666 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 PANTHER PTHR11624:SF1 1 305 0.0 T 22-04-2016 TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 PANTHER PTHR11624:SF1 338 666 0.0 T 22-04-2016 TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 ProSitePatterns PS00801 Transketolase signature 1. 13 33 - T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 SUPERFAMILY SSF52518 6 322 2.14E-119 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 TIGRFAM TIGR00232 tktlase_bact: transketolase 7 665 0.0 T 22-04-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 Gene3D G3DSA:3.40.50.920 540 665 1.7E-46 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 SMART SM00861 356 528 2.6E-65 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 SUPERFAMILY SSF52922 535 666 6.67E-41 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS10990 c9d74e5cedd3955b3a28220c74faf966 666 Pfam PF02780 Transketolase, C-terminal domain 542 657 7.6E-20 T 22-04-2016 IPR033248 Transketolase, C-terminal domain TOLA_RS12935 3337f749467e6a2393f28051c63c307a 177 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.177 T 22-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 TOLA_RS12935 3337f749467e6a2393f28051c63c307a 177 Pfam PF00719 Inorganic pyrophosphatase 18 173 1.8E-52 T 22-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 TOLA_RS12935 3337f749467e6a2393f28051c63c307a 177 PANTHER PTHR10286 6 175 2.1E-77 T 22-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 TOLA_RS12935 3337f749467e6a2393f28051c63c307a 177 Gene3D G3DSA:3.90.80.10 6 175 1.3E-59 T 22-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 TOLA_RS12935 3337f749467e6a2393f28051c63c307a 177 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 22-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 TOLA_RS12935 3337f749467e6a2393f28051c63c307a 177 SUPERFAMILY SSF50324 6 174 2.62E-65 T 22-04-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 TOLA_RS02345 4473110dc82f915f0e7caf9da8c051c3 459 Gene3D G3DSA:3.20.20.80 3 459 6.6E-145 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS02345 4473110dc82f915f0e7caf9da8c051c3 459 PANTHER PTHR10353:SF73 1 459 0.0 T 22-04-2016 TOLA_RS02345 4473110dc82f915f0e7caf9da8c051c3 459 SUPERFAMILY SSF51445 1 459 9.56E-161 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS02345 4473110dc82f915f0e7caf9da8c051c3 459 Pfam PF00232 Glycosyl hydrolase family 1 2 459 1.5E-132 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS02345 4473110dc82f915f0e7caf9da8c051c3 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 383 394 4.3E-14 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS02345 4473110dc82f915f0e7caf9da8c051c3 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 288 302 4.3E-14 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS02345 4473110dc82f915f0e7caf9da8c051c3 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 428 440 4.3E-14 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS02345 4473110dc82f915f0e7caf9da8c051c3 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 360 368 4.3E-14 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS02345 4473110dc82f915f0e7caf9da8c051c3 459 PRINTS PR00131 Glycosyl hydrolase family 1 signature 404 421 4.3E-14 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS02345 4473110dc82f915f0e7caf9da8c051c3 459 PANTHER PTHR10353 1 459 0.0 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS02345 4473110dc82f915f0e7caf9da8c051c3 459 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 360 368 - T 22-04-2016 IPR018120 Glycoside hydrolase family 1, active site TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 14 856 0.0 T 22-04-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 SMART SM00534 611 798 1.4E-118 T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 692 708 - T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 14 851 25.572 T 22-04-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 Gene3D G3DSA:3.40.50.300 572 801 3.9E-85 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 Pfam PF05190 MutS family domain IV 432 522 2.3E-29 T 22-04-2016 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 Pfam PF05192 MutS domain III 276 563 2.4E-38 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 SUPERFAMILY SSF48334 274 569 1.12E-87 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 PANTHER PTHR11361 8 865 0.0 T 22-04-2016 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 SUPERFAMILY SSF53150 121 273 2.75E-42 T 22-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 PIRSF PIRSF037677 3 844 3.1E-157 T 22-04-2016 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 Pfam PF05188 MutS domain II 135 260 1.6E-29 T 22-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 Gene3D G3DSA:3.30.420.110 133 263 1.1E-40 T 22-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 Pfam PF00488 MutS domain V 614 801 4.2E-88 T 22-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 SUPERFAMILY SSF52540 571 802 2.77E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 PANTHER PTHR11361:SF86 8 865 0.0 T 22-04-2016 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 Gene3D G3DSA:1.10.1420.10 271 472 1.3E-53 T 22-04-2016 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 SUPERFAMILY SSF55271 8 122 8.89E-44 T 22-04-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 Pfam PF01624 MutS domain I 15 126 8.0E-43 T 22-04-2016 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 Gene3D G3DSA:3.40.1170.10 8 127 2.2E-52 T 22-04-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 TOLA_RS13970 ed16600b757ba780581bb6278b097655 865 SMART SM00533 290 595 4.7E-103 T 22-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 TOLA_RS11080 28933645a60611b2b3b4d64433e3ca2c 68 ProDom PD055267 YTFK Y0656 CYTOPLASMIC VP2585 VV0426 ESCHERICHIA S4534 VC2473 YPO3527 COLI 1 63 2.0E-13 T 22-04-2016 IPR009491 Protein of unknown function DUF1107 TOLA_RS11080 28933645a60611b2b3b4d64433e3ca2c 68 Pfam PF06526 Protein of unknown function (DUF1107) 2 62 9.7E-28 T 22-04-2016 IPR009491 Protein of unknown function DUF1107 TOLA_RS11080 28933645a60611b2b3b4d64433e3ca2c 68 Gene3D G3DSA:3.30.1910.10 2 63 4.5E-25 T 22-04-2016 TOLA_RS16015 34b11ccf34bf739dd4ad30e12c2a1b6e 276 Pfam PF01678 Diaminopimelate epimerase 5 124 5.5E-35 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS16015 34b11ccf34bf739dd4ad30e12c2a1b6e 276 Pfam PF01678 Diaminopimelate epimerase 154 269 2.2E-30 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS16015 34b11ccf34bf739dd4ad30e12c2a1b6e 276 SUPERFAMILY SSF54506 3 276 1.49E-53 T 22-04-2016 TOLA_RS16015 34b11ccf34bf739dd4ad30e12c2a1b6e 276 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 22-04-2016 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS16015 34b11ccf34bf739dd4ad30e12c2a1b6e 276 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 3 275 3.4E-99 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS16015 34b11ccf34bf739dd4ad30e12c2a1b6e 276 Gene3D G3DSA:3.10.310.10 123 264 1.4E-50 T 22-04-2016 TOLA_RS16015 34b11ccf34bf739dd4ad30e12c2a1b6e 276 PANTHER PTHR31689 1 276 5.4E-135 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS16015 34b11ccf34bf739dd4ad30e12c2a1b6e 276 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 276 38.829 T 22-04-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS16015 34b11ccf34bf739dd4ad30e12c2a1b6e 276 Gene3D G3DSA:3.10.310.10 3 122 1.1E-49 T 22-04-2016 TOLA_RS16015 34b11ccf34bf739dd4ad30e12c2a1b6e 276 PANTHER PTHR31689:SF0 1 276 5.4E-135 T 22-04-2016 TOLA_RS15165 99a0afc91675920c0eabdea3a593d7ba 87 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 13 86 2.0E-22 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15165 99a0afc91675920c0eabdea3a593d7ba 87 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.359 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15165 99a0afc91675920c0eabdea3a593d7ba 87 Gene3D G3DSA:1.20.58.110 3 86 1.1E-31 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15165 99a0afc91675920c0eabdea3a593d7ba 87 SUPERFAMILY SSF46992 3 85 1.83E-31 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15165 99a0afc91675920c0eabdea3a593d7ba 87 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 84 1.7E-30 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15165 99a0afc91675920c0eabdea3a593d7ba 87 Pfam PF01649 Ribosomal protein S20 2 83 1.9E-28 T 22-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15165 99a0afc91675920c0eabdea3a593d7ba 87 PANTHER PTHR33398 2 83 9.0E-36 T 22-04-2016 TOLA_RS12685 724acee45e3db4308f28415d7e12e8b3 246 PANTHER PTHR11921 3 240 1.7E-98 T 22-04-2016 TOLA_RS12685 724acee45e3db4308f28415d7e12e8b3 246 SUPERFAMILY SSF54292 4 106 3.38E-29 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TOLA_RS12685 724acee45e3db4308f28415d7e12e8b3 246 Gene3D G3DSA:3.10.20.30 4 106 4.6E-37 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS12685 724acee45e3db4308f28415d7e12e8b3 246 Gene3D G3DSA:1.10.1060.10 107 240 5.3E-38 T 22-04-2016 TOLA_RS12685 724acee45e3db4308f28415d7e12e8b3 246 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 150 161 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS12685 724acee45e3db4308f28415d7e12e8b3 246 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 56 64 - T 22-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TOLA_RS12685 724acee45e3db4308f28415d7e12e8b3 246 Pfam PF13183 4Fe-4S dicluster domain 147 220 2.9E-12 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TOLA_RS12685 724acee45e3db4308f28415d7e12e8b3 246 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 9 228 4.7E-90 T 22-04-2016 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 TOLA_RS12685 724acee45e3db4308f28415d7e12e8b3 246 SUPERFAMILY SSF46548 107 233 3.14E-33 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 TOLA_RS12685 724acee45e3db4308f28415d7e12e8b3 246 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 7 111 3.9E-38 T 22-04-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 7 196 3.9E-71 T 22-04-2016 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 5 333 41.023 T 22-04-2016 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0042132|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 208 235 3.0E-66 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 307 332 3.0E-66 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 151 174 3.0E-66 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 67 93 3.0E-66 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 30 57 3.0E-66 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 182 205 3.0E-66 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 PANTHER PTHR11556 10 327 1.1E-174 T 22-04-2016 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0042132|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 273 285 - T 22-04-2016 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 Gene3D G3DSA:3.40.190.80 199 330 5.9E-54 T 22-04-2016 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 PIRSF PIRSF000904 1 335 3.1E-117 T 22-04-2016 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0042132|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 SUPERFAMILY SSF56655 4 329 2.49E-106 T 22-04-2016 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 Gene3D G3DSA:3.30.540.10 6 198 4.4E-74 T 22-04-2016 TOLA_RS09605 e3331113e8f2ae92921a5501d03d6574 336 PIRSF PIRSF500210 1 335 1.1E-121 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS10435 20b8b928e73e827e9a9b2f57cd8f7dd8 371 Gene3D G3DSA:3.40.50.720 2 204 4.3E-49 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10435 20b8b928e73e827e9a9b2f57cd8f7dd8 371 SUPERFAMILY SSF51735 2 350 4.76E-89 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10435 20b8b928e73e827e9a9b2f57cd8f7dd8 371 PANTHER PTHR10366 3 281 3.2E-212 T 22-04-2016 TOLA_RS10435 20b8b928e73e827e9a9b2f57cd8f7dd8 371 PANTHER PTHR10366 309 352 3.2E-212 T 22-04-2016 TOLA_RS10435 20b8b928e73e827e9a9b2f57cd8f7dd8 371 PANTHER PTHR10366:SF32 3 281 3.2E-212 T 22-04-2016 TOLA_RS10435 20b8b928e73e827e9a9b2f57cd8f7dd8 371 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 2 351 5.8E-177 T 22-04-2016 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|UniPathway: UPA00128 TOLA_RS10435 20b8b928e73e827e9a9b2f57cd8f7dd8 371 PANTHER PTHR10366:SF32 309 352 3.2E-212 T 22-04-2016 TOLA_RS10435 20b8b928e73e827e9a9b2f57cd8f7dd8 371 Gene3D G3DSA:3.90.25.10 205 246 6.9E-51 T 22-04-2016 TOLA_RS10435 20b8b928e73e827e9a9b2f57cd8f7dd8 371 Gene3D G3DSA:3.90.25.10 303 362 6.9E-51 T 22-04-2016 TOLA_RS10435 20b8b928e73e827e9a9b2f57cd8f7dd8 371 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 2 355 56.266 T 22-04-2016 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|UniPathway: UPA00128 TOLA_RS10435 20b8b928e73e827e9a9b2f57cd8f7dd8 371 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 345 2.4E-160 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 Gene3D G3DSA:3.30.565.10 280 450 2.5E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 SUPERFAMILY SSF55874 284 449 1.33E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 Gene3D G3DSA:1.10.287.130 221 279 1.7E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 2.7E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 429 2.7E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 409 2.7E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 448 2.7E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 SMART SM00387 343 451 2.5E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 Pfam PF00672 HAMP domain 157 226 7.1E-10 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 SUPERFAMILY SSF47384 219 294 4.12E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 SMART SM00388 231 294 1.9E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 SMART SM00304 175 230 6.3E-4 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 294 4.5E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 448 1.0E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 SUPERFAMILY SSF158472 175 229 1.83E-6 T 22-04-2016 TOLA_RS04465 e741949249a4292168d58ffcc1ae36d3 454 PANTHER PTHR24423 131 448 4.2E-63 T 22-04-2016 TOLA_RS13255 29c407054539757823ca790c870ac2bb 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.8E-19 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS13255 29c407054539757823ca790c870ac2bb 300 SUPERFAMILY SSF53850 86 296 3.57E-49 T 22-04-2016 TOLA_RS13255 29c407054539757823ca790c870ac2bb 300 SUPERFAMILY SSF46785 1 110 5.81E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13255 29c407054539757823ca790c870ac2bb 300 Gene3D G3DSA:1.10.10.10 1 84 4.4E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13255 29c407054539757823ca790c870ac2bb 300 PANTHER PTHR30346:SF15 1 296 3.5E-134 T 22-04-2016 TOLA_RS13255 29c407054539757823ca790c870ac2bb 300 Pfam PF03466 LysR substrate binding domain 88 293 4.3E-54 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS13255 29c407054539757823ca790c870ac2bb 300 Gene3D G3DSA:3.40.190.10 90 175 1.4E-21 T 22-04-2016 TOLA_RS13255 29c407054539757823ca790c870ac2bb 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS13255 29c407054539757823ca790c870ac2bb 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS13255 29c407054539757823ca790c870ac2bb 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS13255 29c407054539757823ca790c870ac2bb 300 Gene3D G3DSA:3.40.190.10 176 267 5.4E-36 T 22-04-2016 TOLA_RS13255 29c407054539757823ca790c870ac2bb 300 PANTHER PTHR30346 1 296 3.5E-134 T 22-04-2016 TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 PANTHER PTHR24423:SF477 159 560 1.4E-44 T 22-04-2016 TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 PANTHER PTHR24423:SF477 780 790 1.4E-44 T 22-04-2016 TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 Pfam PF08447 PAS fold 323 405 1.1E-16 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 Pfam PF08447 PAS fold 450 537 8.6E-13 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 553 680 1.9E-8 T 22-04-2016 IPR000014 PAS domain TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 297 421 2.4E-27 T 22-04-2016 IPR000014 PAS domain TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 SMART SM00267 673 845 1.6E-46 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 Gene3D G3DSA:3.30.450.20 555 671 1.4E-15 T 22-04-2016 TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 PANTHER PTHR24423 159 560 1.4E-44 T 22-04-2016 TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 PANTHER PTHR24423 780 790 1.4E-44 T 22-04-2016 TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 SMART SM00091 555 623 0.0015 T 22-04-2016 IPR000014 PAS domain TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 SMART SM00091 427 495 2.8 T 22-04-2016 IPR000014 PAS domain TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 SMART SM00091 300 366 4.4E-13 T 22-04-2016 IPR000014 PAS domain TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 SUPERFAMILY SSF55073 689 844 1.02E-41 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 SUPERFAMILY SSF55785 288 412 1.21E-26 T 22-04-2016 IPR000014 PAS domain TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 SUPERFAMILY SSF55785 434 544 9.25E-14 T 22-04-2016 IPR000014 PAS domain TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 SUPERFAMILY SSF55785 540 671 5.8E-15 T 22-04-2016 IPR000014 PAS domain TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 682 844 4.3E-39 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 Gene3D G3DSA:3.30.450.20 411 554 6.7E-22 T 22-04-2016 TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 SMART SM00086 631 673 3.4 T 22-04-2016 IPR001610 PAC motif TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 SMART SM00086 373 415 2.2E-8 T 22-04-2016 IPR001610 PAC motif TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 SMART SM00086 501 543 0.093 T 22-04-2016 IPR001610 PAC motif TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 Gene3D G3DSA:3.30.450.20 290 410 5.3E-27 T 22-04-2016 TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 Pfam PF13426 PAS domain 566 672 3.3E-4 T 22-04-2016 IPR000014 PAS domain TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 Pfam PF00990 Diguanylate cyclase, GGDEF domain 684 840 2.4E-37 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS14410 610ac0237e6d8e34602a255de3997830 849 Gene3D G3DSA:3.30.70.270 686 845 1.2E-46 T 22-04-2016 TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.1E-11 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.1E-11 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 SUPERFAMILY SSF100950 74 235 4.61E-28 T 22-04-2016 TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 Gene3D G3DSA:1.10.10.10 1 58 1.3E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 Pfam PF00455 DeoR C terminal sensor domain 76 233 1.8E-52 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 22-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 PANTHER PTHR30363 1 249 2.6E-112 T 22-04-2016 TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 SMART SM01134 73 234 5.8E-70 T 22-04-2016 TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 8.9E-25 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 Gene3D G3DSA:3.30.750.70 77 154 5.1E-16 T 22-04-2016 TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 SUPERFAMILY SSF46785 3 69 1.98E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 PANTHER PTHR30363:SF1 1 249 2.6E-112 T 22-04-2016 TOLA_RS00360 074ef51838a9a2b8c0fda94615464950 253 SMART SM00420 6 58 3.1E-25 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 SUPERFAMILY SSF51905 238 613 2.18E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 582 688 1.5E-28 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 411 436 2.8E-54 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 284 2.8E-54 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 665 685 2.8E-54 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 499 513 2.8E-54 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 643 658 2.8E-54 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 578 599 2.8E-54 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 371 380 2.8E-54 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 540 547 2.8E-54 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 237 259 2.8E-54 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PANTHER PTHR22912:SF29 221 694 1.6E-148 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 Gene3D G3DSA:3.50.50.60 378 567 6.0E-47 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 Gene3D G3DSA:3.50.50.60 237 377 6.5E-30 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 270 280 - T 22-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 Gene3D G3DSA:3.30.390.30 576 693 7.6E-39 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 SUPERFAMILY SSF55424 578 694 3.95E-36 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 237 560 6.4E-56 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PANTHER PTHR22912 221 694 1.6E-148 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 525 547 2.6E-25 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 411 429 2.6E-25 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 238 257 2.6E-25 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 498 514 2.6E-25 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 368 386 2.6E-25 T 22-04-2016 TOLA_RS05120 180a82ad4aa04ac80a3241de0b68f9fb 717 Pfam PF09335 SNARE associated Golgi protein 66 182 5.4E-22 T 22-04-2016 IPR032816 SNARE associated Golgi protein TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 386 3.4E-117 T 22-04-2016 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 UniPathway: UPA00232 TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 3.5E-20 T 22-04-2016 TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 3.5E-20 T 22-04-2016 TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 3.5E-20 T 22-04-2016 TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 3.5E-20 T 22-04-2016 TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 Pfam PF01494 FAD binding domain 5 337 2.5E-28 T 22-04-2016 IPR002938 FAD-binding domain GO:0071949 TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 SUPERFAMILY SSF51905 4 172 1.89E-53 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 SUPERFAMILY SSF51905 263 378 1.89E-53 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 Gene3D G3DSA:3.50.50.60 4 177 1.2E-46 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 Gene3D G3DSA:3.50.50.60 264 352 1.2E-46 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 290 303 - T 22-04-2016 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 UniPathway: UPA00232 TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 PANTHER PTHR13789:SF5 1 390 4.7E-126 T 22-04-2016 TOLA_RS04775 11cc0ffc5c6d3dc13672d8f9ea562765 396 PANTHER PTHR13789 1 390 4.7E-126 T 22-04-2016 TOLA_RS00610 f5b4a9746ba68642110d39c8a9dcfd9f 60 PIRSF PIRSF002211 1 60 1.3E-26 T 22-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 TOLA_RS00610 f5b4a9746ba68642110d39c8a9dcfd9f 60 PANTHER PTHR15892 4 60 3.4E-27 T 22-04-2016 TOLA_RS00610 f5b4a9746ba68642110d39c8a9dcfd9f 60 Gene3D G3DSA:3.30.1390.20 4 60 6.5E-29 T 22-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TOLA_RS00610 f5b4a9746ba68642110d39c8a9dcfd9f 60 Pfam PF00327 Ribosomal protein L30p/L7e 6 56 2.1E-18 T 22-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TOLA_RS00610 f5b4a9746ba68642110d39c8a9dcfd9f 60 SUPERFAMILY SSF55129 4 60 4.45E-21 T 22-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TOLA_RS00610 f5b4a9746ba68642110d39c8a9dcfd9f 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 24 56 - T 22-04-2016 IPR018038 Ribosomal protein L30, conserved site TOLA_RS00610 f5b4a9746ba68642110d39c8a9dcfd9f 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 60 3.9E-24 T 22-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 TOLA_RS00610 f5b4a9746ba68642110d39c8a9dcfd9f 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 3 60 21.469 T 22-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 TOLA_RS13040 dbc4b5303439bfde4e6549ef817d13cd 127 PANTHER PTHR28259 1 118 2.9E-33 T 22-04-2016 TOLA_RS13040 dbc4b5303439bfde4e6549ef817d13cd 127 TIGRFAM TIGR00494 crcB: protein CrcB 6 118 4.2E-29 T 22-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TOLA_RS13040 dbc4b5303439bfde4e6549ef817d13cd 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 117 9.0E-22 T 22-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TOLA_RS13040 dbc4b5303439bfde4e6549ef817d13cd 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 122 18.219 T 22-04-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TOLA_RS07320 03f0038547ae631fd2dcdae459f41497 380 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 7 364 39.358 T 22-04-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TOLA_RS07320 03f0038547ae631fd2dcdae459f41497 380 SUPERFAMILY SSF56059 103 299 2.83E-55 T 22-04-2016 TOLA_RS07320 03f0038547ae631fd2dcdae459f41497 380 PANTHER PTHR11609 1 367 3.2E-124 T 22-04-2016 TOLA_RS07320 03f0038547ae631fd2dcdae459f41497 380 SUPERFAMILY SSF51246 304 366 1.18E-15 T 22-04-2016 IPR011054 Rudiment single hybrid motif TOLA_RS07320 03f0038547ae631fd2dcdae459f41497 380 PANTHER PTHR11609:SF5 1 367 3.2E-124 T 22-04-2016 TOLA_RS07320 03f0038547ae631fd2dcdae459f41497 380 Pfam PF02222 ATP-grasp domain 112 280 5.3E-43 T 22-04-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UniPathway: UPA00074 TOLA_RS07320 03f0038547ae631fd2dcdae459f41497 380 Gene3D G3DSA:3.30.470.20 143 378 2.1E-77 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS07320 03f0038547ae631fd2dcdae459f41497 380 SUPERFAMILY SSF52440 6 101 2.01E-26 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS07320 03f0038547ae631fd2dcdae459f41497 380 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 7 364 2.7E-115 T 22-04-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TOLA_RS07320 03f0038547ae631fd2dcdae459f41497 380 Gene3D G3DSA:3.40.50.20 2 111 4.7E-32 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS11095 4750881d4db06eb224e7a91939bfe468 258 PANTHER PTHR10060:SF20 2 257 3.3E-130 T 22-04-2016 TOLA_RS11095 4750881d4db06eb224e7a91939bfe468 258 PANTHER PTHR10060 2 257 3.3E-130 T 22-04-2016 IPR001130 TatD family GO:0016788 TOLA_RS11095 4750881d4db06eb224e7a91939bfe468 258 Pfam PF01026 TatD related DNase 3 253 2.3E-79 T 22-04-2016 IPR001130 TatD family GO:0016788 TOLA_RS11095 4750881d4db06eb224e7a91939bfe468 258 PIRSF PIRSF005902 1 257 2.7E-80 T 22-04-2016 IPR001130 TatD family GO:0016788 TOLA_RS11095 4750881d4db06eb224e7a91939bfe468 258 SUPERFAMILY SSF51556 2 255 4.01E-87 T 22-04-2016 IPR032466 Metal-dependent hydrolase TOLA_RS11095 4750881d4db06eb224e7a91939bfe468 258 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 254 1.1E-89 T 22-04-2016 IPR015991 Uncharacterised deoxyribonuclease TatD-type GO:0004536 TOLA_RS11095 4750881d4db06eb224e7a91939bfe468 258 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 22-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 TOLA_RS11095 4750881d4db06eb224e7a91939bfe468 258 Gene3D G3DSA:3.20.20.140 2 254 1.7E-88 T 22-04-2016 TOLA_RS13915 b755df1b6b7f0b90f14525be4a10e456 464 Gene3D G3DSA:1.10.860.10 19 121 1.4E-39 T 22-04-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal TOLA_RS13915 b755df1b6b7f0b90f14525be4a10e456 464 PANTHER PTHR30153 3 464 5.9E-215 T 22-04-2016 TOLA_RS13915 b755df1b6b7f0b90f14525be4a10e456 464 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 18 456 4.1E-174 T 22-04-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 TOLA_RS13915 b755df1b6b7f0b90f14525be4a10e456 464 SUPERFAMILY SSF52540 196 267 2.26E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13915 b755df1b6b7f0b90f14525be4a10e456 464 SUPERFAMILY SSF52540 294 447 2.26E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13915 b755df1b6b7f0b90f14525be4a10e456 464 SMART SM00382 215 421 0.0021 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS13915 b755df1b6b7f0b90f14525be4a10e456 464 SUPERFAMILY SSF48024 17 128 5.23E-38 T 22-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 TOLA_RS13915 b755df1b6b7f0b90f14525be4a10e456 464 Pfam PF00772 DnaB-like helicase N terminal domain 19 120 4.7E-36 T 22-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 TOLA_RS13915 b755df1b6b7f0b90f14525be4a10e456 464 Pfam PF03796 DnaB-like helicase C terminal domain 198 454 9.3E-114 T 22-04-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 TOLA_RS13915 b755df1b6b7f0b90f14525be4a10e456 464 Gene3D G3DSA:3.40.50.300 182 456 1.9E-104 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12585 b7f29399f659327092a5798350b7ffe7 401 PANTHER PTHR36178 1 396 1.7E-99 T 22-04-2016 TOLA_RS12585 b7f29399f659327092a5798350b7ffe7 401 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 2 398 1.3E-107 T 22-04-2016 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 TOLA_RS12585 b7f29399f659327092a5798350b7ffe7 401 Pfam PF03616 Sodium/glutamate symporter 2 371 3.3E-94 T 22-04-2016 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 TOLA_RS12585 b7f29399f659327092a5798350b7ffe7 401 PANTHER PTHR36178:SF1 1 396 1.7E-99 T 22-04-2016 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 Gene3D G3DSA:1.10.10.10 1 51 3.7E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 4.4E-21 T 22-04-2016 TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 SMART SM00344 3 113 2.8E-45 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 Gene3D G3DSA:3.30.70.920 56 141 4.9E-30 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 SUPERFAMILY SSF46785 2 61 3.02E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 2.8E-19 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 2.8E-19 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 2.8E-19 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 PANTHER PTHR30154 1 156 2.3E-83 T 22-04-2016 TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 SUPERFAMILY SSF54909 64 153 1.34E-20 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 22-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 Pfam PF01037 Lrp/AsnC ligand binding domain 69 144 3.4E-23 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TOLA_RS02815 9a78a7e271c3868b2bff860f262e0459 157 PANTHER PTHR30154:SF19 1 156 2.3E-83 T 22-04-2016 TOLA_RS14190 bcc9eaacb90ae02d48d79071d31502c3 326 SUPERFAMILY SSF55174 18 68 3.36E-8 T 22-04-2016 TOLA_RS14190 bcc9eaacb90ae02d48d79071d31502c3 326 SMART SM00363 18 76 4.6E-6 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS14190 bcc9eaacb90ae02d48d79071d31502c3 326 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 15 313 5.7E-103 T 22-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS14190 bcc9eaacb90ae02d48d79071d31502c3 326 PANTHER PTHR11079 6 323 3.6E-142 T 22-04-2016 TOLA_RS14190 bcc9eaacb90ae02d48d79071d31502c3 326 Pfam PF00849 RNA pseudouridylate synthase 92 242 8.4E-33 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS14190 bcc9eaacb90ae02d48d79071d31502c3 326 Gene3D G3DSA:3.10.290.10 19 67 1.6E-9 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS14190 bcc9eaacb90ae02d48d79071d31502c3 326 SUPERFAMILY SSF55120 77 322 2.26E-79 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS14190 bcc9eaacb90ae02d48d79071d31502c3 326 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 22-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS14190 bcc9eaacb90ae02d48d79071d31502c3 326 Pfam PF01479 S4 domain 19 65 2.1E-7 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS14190 bcc9eaacb90ae02d48d79071d31502c3 326 PANTHER PTHR11079:SF73 6 323 3.6E-142 T 22-04-2016 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 5 331 5.7E-118 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 399 410 - T 22-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 Pfam PF00391 PEP-utilising enzyme, mobile domain 369 440 9.4E-27 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 SUPERFAMILY SSF52009 333 452 5.23E-35 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 679 697 - T 22-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 Gene3D G3DSA:3.30.1490.20 2 180 1.7E-62 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 PIRSF PIRSF000854 1 776 0.0 T 22-04-2016 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 Gene3D G3DSA:3.50.30.10 359 458 8.6E-37 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 SUPERFAMILY SSF56059 2 370 4.36E-103 T 22-04-2016 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 SUPERFAMILY SSF51621 450 772 4.71E-97 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 PANTHER PTHR22931:SF7 270 772 0.0 T 22-04-2016 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 PANTHER PTHR22931:SF7 1 254 0.0 T 22-04-2016 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 1 770 0.0 T 22-04-2016 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 PANTHER PTHR22931 270 772 0.0 T 22-04-2016 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 PANTHER PTHR22931 1 254 0.0 T 22-04-2016 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 Gene3D G3DSA:3.20.20.60 466 771 4.3E-102 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 Gene3D G3DSA:3.30.470.20 182 334 7.6E-62 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS09610 3c795a7c9817310bc310b890a3552618 776 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 459 766 2.5E-59 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TOLA_RS08020 2d1f617b072401228cc55d1e826a6b39 636 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 6 627 26.41 T 22-04-2016 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 TOLA_RS08020 2d1f617b072401228cc55d1e826a6b39 636 Gene3D G3DSA:3.50.50.60 544 623 2.4E-27 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS08020 2d1f617b072401228cc55d1e826a6b39 636 Gene3D G3DSA:3.50.50.60 249 334 2.4E-27 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS08020 2d1f617b072401228cc55d1e826a6b39 636 Gene3D G3DSA:3.50.50.60 374 456 2.4E-27 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS08020 2d1f617b072401228cc55d1e826a6b39 636 Pfam PF01266 FAD dependent oxidoreductase 257 603 5.1E-40 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TOLA_RS08020 2d1f617b072401228cc55d1e826a6b39 636 PANTHER PTHR13847:SF182 225 627 3.5E-71 T 22-04-2016 TOLA_RS08020 2d1f617b072401228cc55d1e826a6b39 636 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 117 242 1.4E-43 T 22-04-2016 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 TOLA_RS08020 2d1f617b072401228cc55d1e826a6b39 636 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 257 628 4.3E-112 T 22-04-2016 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 TOLA_RS08020 2d1f617b072401228cc55d1e826a6b39 636 PANTHER PTHR13847 225 627 3.5E-71 T 22-04-2016 TOLA_RS08020 2d1f617b072401228cc55d1e826a6b39 636 SUPERFAMILY SSF51905 257 512 1.17E-26 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS08020 2d1f617b072401228cc55d1e826a6b39 636 Gene3D G3DSA:3.40.50.150 10 248 1.8E-97 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 PANTHER PTHR11964 4 376 1.6E-279 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 Gene3D G3DSA:3.30.300.10 10 134 2.9E-50 T 22-04-2016 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 4 380 2.1E-196 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 SUPERFAMILY SSF55973 110 232 1.02E-48 T 22-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 PIRSF PIRSF000497 1 381 1.3E-174 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 381 59.272 T 22-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 259 267 - T 22-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 115 125 - T 22-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 Pfam PF02772 S-adenosylmethionine synthetase, central domain 113 231 2.1E-43 T 22-04-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 Gene3D G3DSA:3.30.300.10 135 233 9.7E-42 T 22-04-2016 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 Gene3D G3DSA:3.30.300.10 244 381 8.0E-72 T 22-04-2016 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 SUPERFAMILY SSF55973 3 108 2.39E-47 T 22-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 3 100 5.0E-43 T 22-04-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 233 370 1.6E-70 T 22-04-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 TOLA_RS06415 8d88453ee94fda2976abeec1f5f3b520 384 SUPERFAMILY SSF55973 233 382 1.61E-72 T 22-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 Pfam PF00459 Inositol monophosphatase family 3 243 1.6E-50 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 PANTHER PTHR20854:SF5 1 248 2.5E-82 T 22-04-2016 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 8 252 6.2E-87 T 22-04-2016 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 SUPERFAMILY SSF56655 4 249 1.05E-72 T 22-04-2016 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 Gene3D G3DSA:3.40.190.80 157 250 3.1E-43 T 22-04-2016 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 212 226 - T 22-04-2016 IPR020550 Inositol monophosphatase, conserved site GO:0046854 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 7.8E-12 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 7.8E-12 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 209 233 7.8E-12 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 7.8E-12 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 PANTHER PTHR20854 1 248 2.5E-82 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 Gene3D G3DSA:3.30.540.10 4 156 5.4E-42 T 22-04-2016 TOLA_RS04805 9aefcbfedadc5a5b295b2ccc2491f74f 252 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 22-04-2016 IPR020583 Inositol monophosphatase, metal-binding site TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 SUPERFAMILY SSF52540 541 668 4.5E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 SUPERFAMILY SSF52540 371 513 4.5E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 Pfam PF11907 Domain of unknown function (DUF3427) 747 1039 6.1E-36 T 22-04-2016 IPR021835 Protein of unknown function DUF3427 TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 SMART SM00490 568 652 1.5E-7 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 Gene3D G3DSA:3.40.50.300 535 667 4.3E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 Gene3D G3DSA:3.40.50.300 310 476 9.6E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 PANTHER PTHR24031:SF311 491 697 1.8E-21 T 22-04-2016 TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 PANTHER PTHR24031:SF311 298 471 1.8E-21 T 22-04-2016 TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 PANTHER PTHR24031:SF311 26 122 1.8E-21 T 22-04-2016 TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 PANTHER PTHR24031:SF311 991 1003 1.8E-21 T 22-04-2016 TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 Pfam PF13091 PLD-like domain 170 279 4.1E-11 T 22-04-2016 IPR025202 Phospholipase D-like domain TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 Gene3D G3DSA:3.30.870.10 143 282 1.2E-6 T 22-04-2016 TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 Pfam PF04851 Type III restriction enzyme, res subunit 318 473 4.2E-35 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 SMART SM00487 316 500 4.2E-13 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 PANTHER PTHR24031 491 697 1.8E-21 T 22-04-2016 TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 PANTHER PTHR24031 298 471 1.8E-21 T 22-04-2016 TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 PANTHER PTHR24031 26 122 1.8E-21 T 22-04-2016 TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 PANTHER PTHR24031 991 1003 1.8E-21 T 22-04-2016 TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 Pfam PF00271 Helicase conserved C-terminal domain 554 650 2.8E-10 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS15975 fc9cd479a20c42136908ec41a113089b 1046 SUPERFAMILY SSF56024 142 282 1.68E-7 T 22-04-2016 TOLA_RS09760 a7c83821c21f222feafe90ffe9585581 358 SMART SM00388 140 200 1.5E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS09760 a7c83821c21f222feafe90ffe9585581 358 SUPERFAMILY SSF47384 124 199 1.77E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS09760 a7c83821c21f222feafe90ffe9585581 358 SMART SM00387 246 355 2.4E-16 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS09760 a7c83821c21f222feafe90ffe9585581 358 PANTHER PTHR24423 81 341 5.7E-65 T 22-04-2016 TOLA_RS09760 a7c83821c21f222feafe90ffe9585581 358 Gene3D G3DSA:1.10.287.130 132 196 2.3E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS09760 a7c83821c21f222feafe90ffe9585581 358 PANTHER PTHR24423:SF538 81 341 5.7E-65 T 22-04-2016 TOLA_RS09760 a7c83821c21f222feafe90ffe9585581 358 SUPERFAMILY SSF55874 189 351 3.93E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS09760 a7c83821c21f222feafe90ffe9585581 358 Gene3D G3DSA:3.30.565.10 212 349 5.6E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS09760 a7c83821c21f222feafe90ffe9585581 358 PANTHER PTHR24423 1 7 5.7E-65 T 22-04-2016 TOLA_RS09760 a7c83821c21f222feafe90ffe9585581 358 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 246 341 1.5E-11 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS09760 a7c83821c21f222feafe90ffe9585581 358 Pfam PF00512 His Kinase A (phospho-acceptor) domain 142 199 5.2E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS09760 a7c83821c21f222feafe90ffe9585581 358 PANTHER PTHR24423:SF538 1 7 5.7E-65 T 22-04-2016 TOLA_RS14380 37f8441ce7874831414fd1e3c150fed7 380 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 6 369 1.7E-69 T 22-04-2016 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 TOLA_RS14380 37f8441ce7874831414fd1e3c150fed7 380 PANTHER PTHR23502 4 373 5.8E-68 T 22-04-2016 TOLA_RS14380 37f8441ce7874831414fd1e3c150fed7 380 PANTHER PTHR23502:SF19 4 373 5.8E-68 T 22-04-2016 TOLA_RS14380 37f8441ce7874831414fd1e3c150fed7 380 Gene3D G3DSA:1.20.1250.20 199 374 1.8E-9 T 22-04-2016 TOLA_RS14380 37f8441ce7874831414fd1e3c150fed7 380 Gene3D G3DSA:1.20.1250.20 2 183 1.0E-28 T 22-04-2016 TOLA_RS14380 37f8441ce7874831414fd1e3c150fed7 380 Pfam PF07690 Major Facilitator Superfamily 10 344 1.7E-41 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS14380 37f8441ce7874831414fd1e3c150fed7 380 SUPERFAMILY SSF103473 4 375 3.27E-57 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS03495 ad22354d1c55fd982000ba10304632b6 199 Pfam PF00694 Aconitase C-terminal domain 1 125 1.0E-37 T 22-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03495 ad22354d1c55fd982000ba10304632b6 199 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 199 44.739 T 22-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03495 ad22354d1c55fd982000ba10304632b6 199 PANTHER PTHR11670 1 199 8.7E-109 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03495 ad22354d1c55fd982000ba10304632b6 199 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 188 8.1E-92 T 22-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03495 ad22354d1c55fd982000ba10304632b6 199 SUPERFAMILY SSF52016 1 193 5.3E-60 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel TOLA_RS03495 ad22354d1c55fd982000ba10304632b6 199 PANTHER PTHR11670:SF27 1 199 8.7E-109 T 22-04-2016 TOLA_RS03495 ad22354d1c55fd982000ba10304632b6 199 Gene3D G3DSA:3.20.19.10 1 195 5.9E-48 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 SUPERFAMILY SSF88697 275 366 3.04E-24 T 22-04-2016 IPR015947 PUA-like domain TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 Pfam PF00696 Amino acid kinase family 4 234 4.9E-46 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 SMART SM00359 276 359 1.5E-17 T 22-04-2016 IPR002478 PUA domain GO:0003723 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 Hamap MF_00456 Glutamate 5-kinase [proB]. 4 257 36.847 T 22-04-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 PRINTS PR00474 Glutamate 5-kinase family signature 75 103 5.2E-55 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 PRINTS PR00474 Glutamate 5-kinase family signature 41 55 5.2E-55 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 PRINTS PR00474 Glutamate 5-kinase family signature 147 174 5.2E-55 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 PRINTS PR00474 Glutamate 5-kinase family signature 115 136 5.2E-55 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 PRINTS PR00474 Glutamate 5-kinase family signature 208 228 5.2E-55 T 22-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 Gene3D G3DSA:2.30.130.10 273 365 1.7E-25 T 22-04-2016 IPR015947 PUA-like domain TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 Pfam PF01472 PUA domain 276 350 3.1E-22 T 22-04-2016 IPR002478 PUA domain GO:0003723 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 SUPERFAMILY SSF53633 4 254 9.82E-70 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 Gene3D G3DSA:3.40.1160.10 2 259 2.3E-61 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 PIRSF PIRSF000729 1 367 9.5E-144 T 22-04-2016 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 ProSitePatterns PS00902 Glutamate 5-kinase signature. 206 223 - T 22-04-2016 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 PANTHER PTHR11063 1 367 9.0E-138 T 22-04-2016 TOLA_RS04150 dfb502c35a33337923993a2c5d283abf 367 TIGRFAM TIGR01027 proB: glutamate 5-kinase 4 366 4.1E-152 T 22-04-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 TOLA_RS07130 ff806b58d3c7ca803a3d990b3fdab3f1 379 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 TOLA_RS07130 ff806b58d3c7ca803a3d990b3fdab3f1 379 Pfam PF00437 Type II/IV secretion system protein 32 246 1.2E-38 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 TOLA_RS07130 ff806b58d3c7ca803a3d990b3fdab3f1 379 Gene3D G3DSA:3.40.50.300 101 344 2.5E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07130 ff806b58d3c7ca803a3d990b3fdab3f1 379 PANTHER PTHR30486:SF3 1 374 7.4E-149 T 22-04-2016 TOLA_RS07130 ff806b58d3c7ca803a3d990b3fdab3f1 379 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 4 341 1.4E-130 T 22-04-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 TOLA_RS07130 ff806b58d3c7ca803a3d990b3fdab3f1 379 PANTHER PTHR30486 1 374 7.4E-149 T 22-04-2016 TOLA_RS07130 ff806b58d3c7ca803a3d990b3fdab3f1 379 SUPERFAMILY SSF52540 6 336 5.09E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07130 ff806b58d3c7ca803a3d990b3fdab3f1 379 SMART SM00382 122 247 0.0097 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 PANTHER PTHR18934 44 695 0.0 T 22-04-2016 TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 602 691 9.7E-17 T 22-04-2016 IPR011709 Domain of unknown function DUF1605 TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 PANTHER PTHR18934 732 860 0.0 T 22-04-2016 TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 SMART SM00487 70 254 4.2E-28 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 Pfam PF00271 Helicase conserved C-terminal domain 283 395 1.3E-10 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 Pfam PF04408 Helicase associated domain (HA2) 458 539 8.6E-18 T 22-04-2016 IPR007502 Helicase-associated domain GO:0004386 TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 SMART SM00382 87 362 1.0E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 Gene3D G3DSA:3.40.50.300 264 407 6.2E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 Gene3D G3DSA:3.40.50.300 72 228 2.1E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 10 1289 0.0 T 22-04-2016 IPR010222 RNA helicase HrpA GO:0004004 TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 SMART SM00847 456 552 1.2E-37 T 22-04-2016 IPR007502 Helicase-associated domain GO:0004386 TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 Pfam PF00270 DEAD/DEAH box helicase 82 228 1.6E-6 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 Pfam PF11898 Domain of unknown function (DUF3418) 705 1289 3.0E-229 T 22-04-2016 IPR024590 RNA helicase HrpA, C-terminal TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 PANTHER PTHR18934:SF109 44 695 0.0 T 22-04-2016 TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 SUPERFAMILY SSF52540 72 575 1.88E-108 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 SMART SM00490 296 396 2.0E-15 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS06520 53264267f4e315bbb69d5f97461b9b62 1293 PANTHER PTHR18934:SF109 732 860 0.0 T 22-04-2016 TOLA_RS13120 9263cd2c64268b1fde78cef50e80685d 296 Hamap MF_02032 2-hydroxy-3-oxopropionate reductase [garR]. 3 296 59.255 T 22-04-2016 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 TOLA_RS13120 9263cd2c64268b1fde78cef50e80685d 296 SUPERFAMILY SSF48179 164 288 7.48E-38 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS13120 9263cd2c64268b1fde78cef50e80685d 296 Gene3D G3DSA:3.40.50.720 2 164 1.1E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS13120 9263cd2c64268b1fde78cef50e80685d 296 PANTHER PTHR22981 1 296 6.5E-194 T 22-04-2016 TOLA_RS13120 9263cd2c64268b1fde78cef50e80685d 296 PANTHER PTHR22981:SF78 1 296 6.5E-194 T 22-04-2016 TOLA_RS13120 9263cd2c64268b1fde78cef50e80685d 296 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 4 294 1.2E-137 T 22-04-2016 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 TOLA_RS13120 9263cd2c64268b1fde78cef50e80685d 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 7 20 - T 22-04-2016 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 TOLA_RS13120 9263cd2c64268b1fde78cef50e80685d 296 SUPERFAMILY SSF51735 3 164 2.3E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS13120 9263cd2c64268b1fde78cef50e80685d 296 PIRSF PIRSF000103 1 294 8.5E-91 T 22-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 TOLA_RS13120 9263cd2c64268b1fde78cef50e80685d 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 286 6.6E-39 T 22-04-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 TOLA_RS13120 9263cd2c64268b1fde78cef50e80685d 296 Gene3D G3DSA:1.10.1040.10 166 294 1.7E-43 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TOLA_RS13120 9263cd2c64268b1fde78cef50e80685d 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 163 8.0E-50 T 22-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 TOLA_RS08940 1e8efcceae6294a8b89694e11a3b3c8a 194 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 2 181 19.336 T 22-04-2016 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 TOLA_RS08940 1e8efcceae6294a8b89694e11a3b3c8a 194 SUPERFAMILY SSF53448 3 178 2.01E-29 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS08940 1e8efcceae6294a8b89694e11a3b3c8a 194 Gene3D G3DSA:3.90.550.10 1 185 9.8E-37 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS08940 1e8efcceae6294a8b89694e11a3b3c8a 194 Pfam PF12804 MobA-like NTP transferase domain 6 120 1.8E-30 T 22-04-2016 IPR025877 MobA-like NTP transferase TOLA_RS08940 1e8efcceae6294a8b89694e11a3b3c8a 194 PANTHER PTHR19136 1 180 1.7E-26 T 22-04-2016 TOLA_RS08940 1e8efcceae6294a8b89694e11a3b3c8a 194 PANTHER PTHR19136:SF81 1 180 1.7E-26 T 22-04-2016 TOLA_RS04710 d1d42def6248ba77208c54307ec40374 208 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 43.537 T 22-04-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 TOLA_RS04710 d1d42def6248ba77208c54307ec40374 208 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 208 2.3E-89 T 22-04-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 TOLA_RS04710 d1d42def6248ba77208c54307ec40374 208 Gene3D G3DSA:3.40.50.2020 2 208 4.6E-74 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS04710 d1d42def6248ba77208c54307ec40374 208 SUPERFAMILY SSF53271 3 206 1.06E-66 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS04710 d1d42def6248ba77208c54307ec40374 208 Pfam PF14681 Uracil phosphoribosyltransferase 7 207 1.2E-63 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS04710 d1d42def6248ba77208c54307ec40374 208 PANTHER PTHR10285 1 197 4.2E-98 T 22-04-2016 TOLA_RS01965 0c662337f317b52ef1ba2496e6a27cbc 300 Gene3D G3DSA:1.10.10.10 4 83 8.3E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01965 0c662337f317b52ef1ba2496e6a27cbc 300 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 4 291 6.5E-107 T 22-04-2016 IPR017685 HTH-type transcriptional regulator ArgP TOLA_RS01965 0c662337f317b52ef1ba2496e6a27cbc 300 PANTHER PTHR30579 1 297 1.3E-115 T 22-04-2016 TOLA_RS01965 0c662337f317b52ef1ba2496e6a27cbc 300 Pfam PF03466 LysR substrate binding domain 96 271 5.9E-13 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS01965 0c662337f317b52ef1ba2496e6a27cbc 300 PANTHER PTHR30579:SF2 1 297 1.3E-115 T 22-04-2016 TOLA_RS01965 0c662337f317b52ef1ba2496e6a27cbc 300 SUPERFAMILY SSF53850 94 272 2.71E-20 T 22-04-2016 TOLA_RS01965 0c662337f317b52ef1ba2496e6a27cbc 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 1.1E-16 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS01965 0c662337f317b52ef1ba2496e6a27cbc 300 SUPERFAMILY SSF46785 4 112 4.77E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01965 0c662337f317b52ef1ba2496e6a27cbc 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 5.8E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS01965 0c662337f317b52ef1ba2496e6a27cbc 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 5.8E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS01965 0c662337f317b52ef1ba2496e6a27cbc 300 Gene3D G3DSA:3.40.190.10 93 198 2.3E-37 T 22-04-2016 TOLA_RS05225 64559af84280ec1b976e640000f4bad3 484 SUPERFAMILY SSF49899 325 481 1.03E-10 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain TOLA_RS05225 64559af84280ec1b976e640000f4bad3 484 SMART SM00640 12 442 2.7E-121 T 22-04-2016 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 TOLA_RS05225 64559af84280ec1b976e640000f4bad3 484 Gene3D G3DSA:2.115.10.20 18 206 6.8E-12 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain TOLA_RS05225 64559af84280ec1b976e640000f4bad3 484 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 12 25 - T 22-04-2016 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 TOLA_RS05225 64559af84280ec1b976e640000f4bad3 484 SUPERFAMILY SSF75005 4 316 4.4E-96 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain TOLA_RS05225 64559af84280ec1b976e640000f4bad3 484 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 12 313 6.1E-95 T 22-04-2016 IPR013148 Glycosyl hydrolase family 32, N-terminal TOLA_RS05225 64559af84280ec1b976e640000f4bad3 484 Gene3D G3DSA:2.60.120.560 295 477 2.6E-17 T 22-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal TOLA_RS05225 64559af84280ec1b976e640000f4bad3 484 PANTHER PTHR30175 7 484 2.9E-119 T 22-04-2016 TOLA_RS05225 64559af84280ec1b976e640000f4bad3 484 PANTHER PTHR30175:SF0 7 484 2.9E-119 T 22-04-2016 TOLA_RS04970 9cdd0afaf0cbaf31ea3bd76d4591e63b 345 PANTHER PTHR30486:SF6 1 344 2.4E-193 T 22-04-2016 TOLA_RS04970 9cdd0afaf0cbaf31ea3bd76d4591e63b 345 PANTHER PTHR30486 1 344 2.4E-193 T 22-04-2016 TOLA_RS04970 9cdd0afaf0cbaf31ea3bd76d4591e63b 345 SMART SM00382 122 247 3.2E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS04970 9cdd0afaf0cbaf31ea3bd76d4591e63b 345 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 TOLA_RS04970 9cdd0afaf0cbaf31ea3bd76d4591e63b 345 Pfam PF00437 Type II/IV secretion system protein 12 269 1.6E-48 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 TOLA_RS04970 9cdd0afaf0cbaf31ea3bd76d4591e63b 345 Gene3D G3DSA:3.40.50.300 100 340 4.8E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04970 9cdd0afaf0cbaf31ea3bd76d4591e63b 345 SUPERFAMILY SSF52540 5 334 6.67E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04970 9cdd0afaf0cbaf31ea3bd76d4591e63b 345 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 342 8.1E-155 T 22-04-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 TOLA_RS14120 07095d82041b60fed1ecc70625f79e20 282 Gene3D G3DSA:1.10.3720.10 8 272 8.9E-55 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS14120 07095d82041b60fed1ecc70625f79e20 282 PANTHER PTHR30222:SF1 15 282 1.2E-78 T 22-04-2016 TOLA_RS14120 07095d82041b60fed1ecc70625f79e20 282 PANTHER PTHR30222 15 282 1.2E-78 T 22-04-2016 TOLA_RS14120 07095d82041b60fed1ecc70625f79e20 282 SUPERFAMILY SSF161098 11 266 1.31E-50 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS14120 07095d82041b60fed1ecc70625f79e20 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 270 4.5E-15 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06000 16fe84d34c2a971f4197f102c5bcefff 260 PANTHER PTHR30136:SF11 1 260 1.6E-135 T 22-04-2016 TOLA_RS06000 16fe84d34c2a971f4197f102c5bcefff 260 SUPERFAMILY SSF55781 77 251 1.24E-43 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS06000 16fe84d34c2a971f4197f102c5bcefff 260 SMART SM00346 7 95 3.6E-29 T 22-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TOLA_RS06000 16fe84d34c2a971f4197f102c5bcefff 260 Pfam PF01614 Bacterial transcriptional regulator 122 247 9.8E-36 T 22-04-2016 IPR014757 Transcription regulator IclR, C-terminal TOLA_RS06000 16fe84d34c2a971f4197f102c5bcefff 260 PANTHER PTHR30136 1 260 1.6E-135 T 22-04-2016 TOLA_RS06000 16fe84d34c2a971f4197f102c5bcefff 260 Pfam PF09339 IclR helix-turn-helix domain 9 58 3.7E-9 T 22-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TOLA_RS06000 16fe84d34c2a971f4197f102c5bcefff 260 Gene3D G3DSA:1.10.10.10 5 76 1.6E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06000 16fe84d34c2a971f4197f102c5bcefff 260 Gene3D G3DSA:3.30.450.40 77 253 2.7E-56 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS06000 16fe84d34c2a971f4197f102c5bcefff 260 SUPERFAMILY SSF46785 7 78 5.63E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 Pfam PF03924 CHASE domain 82 273 9.3E-48 T 22-04-2016 IPR006189 CHASE domain TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 Gene3D G3DSA:3.30.450.20 352 471 3.0E-28 T 22-04-2016 TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 SUPERFAMILY SSF55785 368 475 3.49E-29 T 22-04-2016 IPR000014 PAS domain TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 Pfam PF00990 Diguanylate cyclase, GGDEF domain 488 643 7.2E-49 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 SUPERFAMILY SSF55073 493 648 3.77E-49 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 485 646 3.1E-46 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 SMART SM00091 363 429 2.0E-9 T 22-04-2016 IPR000014 PAS domain TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 Gene3D G3DSA:3.30.70.270 489 649 2.6E-54 T 22-04-2016 TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 PANTHER PTHR10799 9 31 6.0E-37 T 22-04-2016 TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 PANTHER PTHR10799:SF774 342 641 6.0E-37 T 22-04-2016 TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 Pfam PF00989 PAS fold 367 474 8.9E-16 T 22-04-2016 IPR013767 PAS fold GO:0006355 TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 SMART SM01079 80 276 2.4E-54 T 22-04-2016 IPR006189 CHASE domain TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 SMART SM00267 477 649 2.2E-64 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 PANTHER PTHR10799 342 641 6.0E-37 T 22-04-2016 TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 367 483 2.3E-20 T 22-04-2016 IPR000014 PAS domain TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 PANTHER PTHR10799:SF774 9 31 6.0E-37 T 22-04-2016 TOLA_RS10565 10eb0fa7a7174e5e67c1eec5671f70e9 658 SMART SM00086 435 477 1.7E-8 T 22-04-2016 IPR001610 PAC motif TOLA_RS08050 d0de6cd4f690f6db12973ed35ff343cb 228 PANTHER PTHR30133:SF1 1 228 2.1E-139 T 22-04-2016 IPR030199 Histidine transport system permease protein HisQ GO:0003333|GO:0016021 TOLA_RS08050 d0de6cd4f690f6db12973ed35ff343cb 228 SUPERFAMILY SSF161098 8 205 1.64E-36 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08050 d0de6cd4f690f6db12973ed35ff343cb 228 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 114 1.9E-18 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 TOLA_RS08050 d0de6cd4f690f6db12973ed35ff343cb 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 219 1.5E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08050 d0de6cd4f690f6db12973ed35ff343cb 228 Gene3D G3DSA:1.10.3720.10 9 219 7.7E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08050 d0de6cd4f690f6db12973ed35ff343cb 228 PANTHER PTHR30133 1 228 2.1E-139 T 22-04-2016 TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 Gene3D G3DSA:1.10.10.10 260 330 3.2E-35 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 253 330 4.0E-36 T 22-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 SUPERFAMILY SSF46785 260 333 2.28E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 PANTHER PTHR13779 1 335 7.2E-191 T 22-04-2016 TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 Gene3D G3DSA:1.10.8.60 186 258 5.0E-33 T 22-04-2016 TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 SMART SM00382 54 181 5.9E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 Gene3D G3DSA:3.40.50.300 23 178 1.5E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 PANTHER PTHR13779:SF25 1 335 7.2E-191 T 22-04-2016 TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 SUPERFAMILY SSF52540 23 254 1.73E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 256 329 4.3E-33 T 22-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 337 184.625 T 22-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 27 329 7.8E-148 T 22-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TOLA_RS13835 a7333e2ed6bca9d6f036002777a62ea2 337 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 238 7.1E-118 T 22-04-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 TOLA_RS08440 6f230d226f111897e6ff9632e87f2249 147 Pfam PF03061 Thioesterase superfamily 55 110 1.2E-8 T 22-04-2016 IPR006683 Thioesterase domain TOLA_RS08440 6f230d226f111897e6ff9632e87f2249 147 Gene3D G3DSA:3.10.129.10 8 137 9.4E-33 T 22-04-2016 IPR029069 HotDog domain TOLA_RS08440 6f230d226f111897e6ff9632e87f2249 147 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 27 108 3.3E-11 T 22-04-2016 IPR003736 Phenylacetic acid degradation-related domain TOLA_RS08440 6f230d226f111897e6ff9632e87f2249 147 PANTHER PTHR12418 30 137 1.2E-12 T 22-04-2016 TOLA_RS08440 6f230d226f111897e6ff9632e87f2249 147 SUPERFAMILY SSF54637 8 135 1.4E-29 T 22-04-2016 IPR029069 HotDog domain TOLA_RS08440 6f230d226f111897e6ff9632e87f2249 147 PANTHER PTHR12418:SF16 30 137 1.2E-12 T 22-04-2016 TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 PANTHER PTHR30363 1 246 1.0E-88 T 22-04-2016 TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 Gene3D G3DSA:1.10.10.10 1 54 8.4E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 Pfam PF00455 DeoR C terminal sensor domain 69 226 4.5E-43 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 SUPERFAMILY SSF46785 2 62 9.67E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 SMART SM01134 67 227 2.6E-49 T 22-04-2016 TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 PANTHER PTHR30363:SF16 1 246 1.0E-88 T 22-04-2016 TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 22 36 1.4E-6 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 36 54 1.4E-6 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 Pfam PF08220 DeoR-like helix-turn-helix domain 4 59 3.2E-17 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 Gene3D G3DSA:3.40.50.1360 70 207 2.8E-9 T 22-04-2016 TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 SUPERFAMILY SSF100950 69 227 6.95E-26 T 22-04-2016 TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 ProSitePatterns PS00894 DeoR-type HTH domain signature. 4 38 - T 22-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 TOLA_RS07775 256cdfaeea0435de91a54d3dc98fefb8 246 SMART SM00420 4 56 2.8E-17 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS03920 9315f3e74254d9e33568d15710161505 110 SUPERFAMILY SSF69754 3 102 1.44E-25 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 TOLA_RS03920 9315f3e74254d9e33568d15710161505 110 PANTHER PTHR33231:SF3 1 96 5.2E-32 T 22-04-2016 TOLA_RS03920 9315f3e74254d9e33568d15710161505 110 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 97 2.1E-21 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 TOLA_RS03920 9315f3e74254d9e33568d15710161505 110 PANTHER PTHR33231 1 96 5.2E-32 T 22-04-2016 TOLA_RS03920 9315f3e74254d9e33568d15710161505 110 Gene3D G3DSA:3.30.160.100 3 91 4.3E-25 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 TOLA_RS03920 9315f3e74254d9e33568d15710161505 110 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 89 9.8E-18 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 TOLA_RS03445 87e7bb6d1dc413b6c0c51ee251e9a154 535 SUPERFAMILY SSF161098 3 256 1.74E-34 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS03445 87e7bb6d1dc413b6c0c51ee251e9a154 535 TIGRFAM TIGR01253 thiP: thiamine/thiamine pyrophosphate ABC transporter, permease protein 6 517 5.3E-140 T 22-04-2016 IPR005947 Thiamine ABC transporter, permease protein GO:0005215|GO:0015888|GO:0016021 TOLA_RS03445 87e7bb6d1dc413b6c0c51ee251e9a154 535 Gene3D G3DSA:1.10.3720.10 287 528 5.8E-23 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS03445 87e7bb6d1dc413b6c0c51ee251e9a154 535 Gene3D G3DSA:1.10.3720.10 14 257 3.1E-27 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS03445 87e7bb6d1dc413b6c0c51ee251e9a154 535 PANTHER PTHR30183 13 528 1.8E-155 T 22-04-2016 TOLA_RS03445 87e7bb6d1dc413b6c0c51ee251e9a154 535 SUPERFAMILY SSF161098 282 521 3.6E-23 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS03445 87e7bb6d1dc413b6c0c51ee251e9a154 535 PANTHER PTHR30183:SF8 13 528 1.8E-155 T 22-04-2016 TOLA_RS03445 87e7bb6d1dc413b6c0c51ee251e9a154 535 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 65 259 3.1E-6 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS03445 87e7bb6d1dc413b6c0c51ee251e9a154 535 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 362 524 5.4E-8 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS02350 45d34cafa98c929c2963b892aab78cad 439 Pfam PF02378 Phosphotransferase system, EIIC 32 351 1.1E-54 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS02350 45d34cafa98c929c2963b892aab78cad 439 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 16 426 1.0E-119 T 22-04-2016 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 TOLA_RS02350 45d34cafa98c929c2963b892aab78cad 439 PANTHER PTHR33989:SF4 2 430 2.2E-151 T 22-04-2016 TOLA_RS02350 45d34cafa98c929c2963b892aab78cad 439 PIRSF PIRSF006351 4 433 8.1E-141 T 22-04-2016 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 TOLA_RS02350 45d34cafa98c929c2963b892aab78cad 439 PANTHER PTHR33989 2 430 2.2E-151 T 22-04-2016 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 PANTHER PTHR13697:SF4 2 306 9.8E-137 T 22-04-2016 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 7 26 1.5E-86 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 32 45 1.5E-86 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 1.5E-86 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 1.5E-86 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 94 110 1.5E-86 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 240 262 1.5E-86 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 1.5E-86 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 1.5E-86 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 1.5E-86 T 22-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 Gene3D G3DSA:3.40.50.450 2 214 1.0E-76 T 22-04-2016 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 PANTHER PTHR13697 2 306 9.8E-137 T 22-04-2016 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 Pfam PF00365 Phosphofructokinase 4 276 1.0E-108 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 4 300 1.5E-128 T 22-04-2016 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 ProSitePatterns PS00433 Phosphofructokinase signature. 244 262 - T 22-04-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 PIRSF PIRSF000532 1 319 1.3E-126 T 22-04-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 2 320 47.346 T 22-04-2016 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS07430 aa94511a7d9097a634fbae88c53076fb 320 SUPERFAMILY SSF53784 3 318 5.23E-114 T 22-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 400 428 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 Gene3D G3DSA:2.160.10.10 242 322 6.7E-17 T 22-04-2016 TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 Pfam PF12804 MobA-like NTP transferase domain 5 116 2.1E-23 T 22-04-2016 IPR025877 MobA-like NTP transferase TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 SUPERFAMILY SSF53448 1 249 9.81E-64 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 Gene3D G3DSA:3.90.550.10 1 241 1.1E-68 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 PANTHER PTHR22572:SF115 4 446 1.1E-222 T 22-04-2016 TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 451 1.4E-197 T 22-04-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 PANTHER PTHR22572 4 446 1.1E-222 T 22-04-2016 TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 264 297 3.5E-5 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 392 426 6.5E-5 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 Gene3D G3DSA:2.160.10.10 323 452 6.8E-31 T 22-04-2016 TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 SUPERFAMILY SSF51161 252 434 3.17E-48 T 22-04-2016 IPR011004 Trimeric LpxA-like TOLA_RS01580 a77d58ebabfe1225d817f29541532929 454 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 449 42.277 T 22-04-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 TOLA_RS08810 628cc1c99b6a7190e5c370ba95bf70f0 262 SMART SM00382 22 203 3.9E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS08810 628cc1c99b6a7190e5c370ba95bf70f0 262 Gene3D G3DSA:3.40.50.300 12 225 3.8E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08810 628cc1c99b6a7190e5c370ba95bf70f0 262 PANTHER PTHR24220:SF558 16 241 1.9E-50 T 22-04-2016 TOLA_RS08810 628cc1c99b6a7190e5c370ba95bf70f0 262 SUPERFAMILY SSF52540 13 222 3.11E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08810 628cc1c99b6a7190e5c370ba95bf70f0 262 Pfam PF00005 ABC transporter 16 163 6.4E-23 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS08810 628cc1c99b6a7190e5c370ba95bf70f0 262 PANTHER PTHR24220 16 241 1.9E-50 T 22-04-2016 TOLA_RS08810 628cc1c99b6a7190e5c370ba95bf70f0 262 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS11470 33543320c00ff182baea26e7dacbb872 197 Gene3D G3DSA:2.30.22.10 133 191 9.9E-28 T 22-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 TOLA_RS11470 33543320c00ff182baea26e7dacbb872 197 Hamap MF_01151 Protein GrpE [grpE]. 4 189 21.375 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 TOLA_RS11470 33543320c00ff182baea26e7dacbb872 197 ProSitePatterns PS01071 grpE protein signature. 144 187 - T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 TOLA_RS11470 33543320c00ff182baea26e7dacbb872 197 SUPERFAMILY SSF58014 36 133 5.49E-28 T 22-04-2016 TOLA_RS11470 33543320c00ff182baea26e7dacbb872 197 PANTHER PTHR21237 38 192 2.4E-66 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 TOLA_RS11470 33543320c00ff182baea26e7dacbb872 197 Gene3D G3DSA:3.90.20.20 36 132 2.2E-31 T 22-04-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil TOLA_RS11470 33543320c00ff182baea26e7dacbb872 197 Pfam PF01025 GrpE 36 189 3.7E-51 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 TOLA_RS11470 33543320c00ff182baea26e7dacbb872 197 SUPERFAMILY SSF51064 135 190 4.18E-20 T 22-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 TOLA_RS11470 33543320c00ff182baea26e7dacbb872 197 PRINTS PR00773 GrpE protein signature 58 74 5.32E-28 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 TOLA_RS11470 33543320c00ff182baea26e7dacbb872 197 PRINTS PR00773 GrpE protein signature 86 101 5.32E-28 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 TOLA_RS11470 33543320c00ff182baea26e7dacbb872 197 PRINTS PR00773 GrpE protein signature 141 156 5.32E-28 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 TOLA_RS11470 33543320c00ff182baea26e7dacbb872 197 PRINTS PR00773 GrpE protein signature 168 187 5.32E-28 T 22-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 TOLA_RS08250 8850bc9085b11e602ded729cd310c4ca 119 SUPERFAMILY SSF51278 1 105 7.72E-49 T 22-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08250 8850bc9085b11e602ded729cd310c4ca 119 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 102 7.4E-47 T 22-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08250 8850bc9085b11e602ded729cd310c4ca 119 Pfam PF00699 Urease beta subunit 3 99 2.2E-45 T 22-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08250 8850bc9085b11e602ded729cd310c4ca 119 PANTHER PTHR33569:SF1 1 103 3.2E-65 T 22-04-2016 TOLA_RS08250 8850bc9085b11e602ded729cd310c4ca 119 Gene3D G3DSA:2.10.150.10 1 108 5.1E-52 T 22-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08250 8850bc9085b11e602ded729cd310c4ca 119 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 32.382 T 22-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08250 8850bc9085b11e602ded729cd310c4ca 119 PANTHER PTHR33569 1 103 3.2E-65 T 22-04-2016 TOLA_RS11165 9b5d520c5999b7676f00bf9760aae989 220 PANTHER PTHR18901:SF40 1 218 1.7E-53 T 22-04-2016 TOLA_RS11165 9b5d520c5999b7676f00bf9760aae989 220 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 50 185 2.6E-9 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS11165 9b5d520c5999b7676f00bf9760aae989 220 Gene3D G3DSA:3.40.50.1000 73 214 4.3E-39 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS11165 9b5d520c5999b7676f00bf9760aae989 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 185 2.7E-33 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS11165 9b5d520c5999b7676f00bf9760aae989 220 SUPERFAMILY SSF56784 1 214 6.2E-56 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS11165 9b5d520c5999b7676f00bf9760aae989 220 Gene3D G3DSA:1.10.150.240 22 72 3.4E-9 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 TOLA_RS11165 9b5d520c5999b7676f00bf9760aae989 220 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 102 179 5.4E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS11165 9b5d520c5999b7676f00bf9760aae989 220 PANTHER PTHR18901 1 218 1.7E-53 T 22-04-2016 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 Gene3D G3DSA:1.20.1250.20 237 415 1.0E-9 T 22-04-2016 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 Gene3D G3DSA:1.20.1250.20 39 206 5.7E-7 T 22-04-2016 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 Gene3D G3DSA:3.40.50.980 652 799 2.3E-19 T 22-04-2016 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 Gene3D G3DSA:3.30.300.30 1053 1144 4.9E-7 T 22-04-2016 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 Gene3D G3DSA:3.40.50.980 800 953 1.5E-43 T 22-04-2016 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 Pfam PF00501 AMP-binding enzyme 647 1048 5.1E-80 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 Pfam PF07690 Major Facilitator Superfamily 39 375 2.1E-14 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 SUPERFAMILY SSF103473 10 416 8.37E-24 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 SUPERFAMILY SSF56801 645 1148 4.71E-104 T 22-04-2016 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 Gene3D G3DSA:3.40.1130.10 437 556 2.9E-15 T 22-04-2016 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 ProSitePatterns PS00455 Putative AMP-binding domain signature. 793 804 - T 22-04-2016 IPR020845 AMP-binding, conserved site TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 SUPERFAMILY SSF69593 426 592 2.48E-25 T 22-04-2016 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 PANTHER PTHR24096 538 1153 2.4E-136 T 22-04-2016 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 Gene3D G3DSA:2.30.38.10 967 1045 1.1E-24 T 22-04-2016 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 Pfam PF01553 Acyltransferase 432 555 1.2E-22 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 SMART SM00563 446 559 9.5E-27 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TOLA_RS16255 3e5f6b438a2ef096a72202b28c82ed6a 1156 PANTHER PTHR24096:SF211 538 1153 2.4E-136 T 22-04-2016 TOLA_RS07790 0573f8daadeca7b397b205f4613cded8 357 Hamap MF_02040 Iron-sulfur cluster carrier protein. 89 338 37.303 T 22-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein TOLA_RS07790 0573f8daadeca7b397b205f4613cded8 357 SUPERFAMILY SSF52540 96 341 6.47E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07790 0573f8daadeca7b397b205f4613cded8 357 PANTHER PTHR23264:SF19 3 352 1.4E-151 T 22-04-2016 TOLA_RS07790 0573f8daadeca7b397b205f4613cded8 357 Gene3D G3DSA:3.40.50.300 85 337 2.2E-105 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07790 0573f8daadeca7b397b205f4613cded8 357 PANTHER PTHR23264 3 352 1.4E-151 T 22-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein TOLA_RS07790 0573f8daadeca7b397b205f4613cded8 357 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 94 337 2.2E-101 T 22-04-2016 IPR019591 Mrp/NBP35 ATP-binding protein TOLA_RS07790 0573f8daadeca7b397b205f4613cded8 357 ProSitePatterns PS01215 Mrp family signature. 201 217 - T 22-04-2016 IPR000808 Mrp, conserved site GO:0005524 TOLA_RS10590 874e8c2036a1d1e5c1320950e2ba4955 204 Pfam PF00510 Cytochrome c oxidase subunit III 13 202 6.1E-15 T 22-04-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 TOLA_RS10590 874e8c2036a1d1e5c1320950e2ba4955 204 SUPERFAMILY SSF81452 20 202 7.85E-58 T 22-04-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 TOLA_RS10590 874e8c2036a1d1e5c1320950e2ba4955 204 Gene3D G3DSA:1.20.120.80 23 202 1.3E-51 T 22-04-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 TOLA_RS10590 874e8c2036a1d1e5c1320950e2ba4955 204 PANTHER PTHR11403 7 204 1.3E-113 T 22-04-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 TOLA_RS10590 874e8c2036a1d1e5c1320950e2ba4955 204 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 26 204 4.0E-88 T 22-04-2016 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 TOLA_RS10590 874e8c2036a1d1e5c1320950e2ba4955 204 PANTHER PTHR11403:SF2 7 204 1.3E-113 T 22-04-2016 TOLA_RS05635 2203c0589fb15be4e33ff321a570b2dd 291 Hamap MF_00188 Protease HtpX [htpX]. 1 290 26.404 T 22-04-2016 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 TOLA_RS05635 2203c0589fb15be4e33ff321a570b2dd 291 PANTHER PTHR10120:SF19 1 291 5.9E-104 T 22-04-2016 TOLA_RS05635 2203c0589fb15be4e33ff321a570b2dd 291 PANTHER PTHR10120 1 291 5.9E-104 T 22-04-2016 TOLA_RS05635 2203c0589fb15be4e33ff321a570b2dd 291 Gene3D G3DSA:3.30.2010.10 73 160 2.4E-31 T 22-04-2016 TOLA_RS05635 2203c0589fb15be4e33ff321a570b2dd 291 Pfam PF01435 Peptidase family M48 81 290 1.4E-40 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 SUPERFAMILY SSF56655 5 330 1.97E-107 T 22-04-2016 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 182 205 9.4E-71 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 151 174 9.4E-71 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 307 332 9.4E-71 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 67 93 9.4E-71 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 208 235 9.4E-71 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 30 57 9.4E-71 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 PANTHER PTHR11556 6 338 1.7E-177 T 22-04-2016 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0042132|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 PIRSF PIRSF500210 1 336 8.3E-124 T 22-04-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 273 285 - T 22-04-2016 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 5 333 41.826 T 22-04-2016 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0042132|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 6 196 2.1E-74 T 22-04-2016 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 Gene3D G3DSA:3.30.540.10 5 198 2.9E-77 T 22-04-2016 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 Gene3D G3DSA:3.40.190.80 199 332 2.9E-54 T 22-04-2016 TOLA_RS11325 2662a38918fed4fc6270925874217751 339 PIRSF PIRSF000904 1 337 2.1E-120 T 22-04-2016 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0042132|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS11635 861d38e27a55053a60a4f764fb9f9938 380 Pfam PF00465 Iron-containing alcohol dehydrogenase 6 367 5.3E-106 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 TOLA_RS11635 861d38e27a55053a60a4f764fb9f9938 380 PANTHER PTHR11496:SF79 3 380 4.4E-156 T 22-04-2016 TOLA_RS11635 861d38e27a55053a60a4f764fb9f9938 380 Gene3D G3DSA:3.40.50.1970 2 177 1.0E-53 T 22-04-2016 TOLA_RS11635 861d38e27a55053a60a4f764fb9f9938 380 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 257 277 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS11635 861d38e27a55053a60a4f764fb9f9938 380 PANTHER PTHR11496 3 380 4.4E-156 T 22-04-2016 TOLA_RS11635 861d38e27a55053a60a4f764fb9f9938 380 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 170 198 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS11635 861d38e27a55053a60a4f764fb9f9938 380 SUPERFAMILY SSF56796 2 378 5.89E-109 T 22-04-2016 TOLA_RS11635 861d38e27a55053a60a4f764fb9f9938 380 Gene3D G3DSA:1.20.1090.10 181 376 2.6E-60 T 22-04-2016 TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 10 704 1.7E-290 T 22-04-2016 IPR017750 ATPase, type I secretion system TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 Gene3D G3DSA:3.90.70.10 8 130 1.7E-32 T 22-04-2016 TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 PANTHER PTHR24221 130 714 0.0 T 22-04-2016 TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 PANTHER PTHR24221 29 70 0.0 T 22-04-2016 TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 SUPERFAMILY SSF90123 143 461 2.62E-48 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 Pfam PF00664 ABC transporter transmembrane region 164 423 1.4E-20 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 SUPERFAMILY SSF52540 465 699 8.5E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 Gene3D G3DSA:3.40.50.300 474 700 2.9E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 Gene3D G3DSA:1.20.1560.10 148 460 8.8E-47 T 22-04-2016 TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 PANTHER PTHR24221:SF248 130 714 0.0 T 22-04-2016 TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 PANTHER PTHR24221:SF248 29 70 0.0 T 22-04-2016 TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 SMART SM00382 501 687 6.1E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS06435 d195d0144ad0630911016b8f2f4f7fae 714 Pfam PF00005 ABC transporter 492 641 2.7E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS10365 a2aeca965a414ca1d6c625b4f38a3d73 354 PANTHER PTHR10366:SF437 3 275 2.9E-159 T 22-04-2016 TOLA_RS10365 a2aeca965a414ca1d6c625b4f38a3d73 354 PANTHER PTHR10366:SF437 299 353 2.9E-159 T 22-04-2016 TOLA_RS10365 a2aeca965a414ca1d6c625b4f38a3d73 354 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 338 1.8E-89 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10365 a2aeca965a414ca1d6c625b4f38a3d73 354 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TOLA_RS10365 a2aeca965a414ca1d6c625b4f38a3d73 354 SUPERFAMILY SSF51735 1 350 8.06E-85 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10365 a2aeca965a414ca1d6c625b4f38a3d73 354 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 352 1.1E-147 T 22-04-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 TOLA_RS10365 a2aeca965a414ca1d6c625b4f38a3d73 354 PANTHER PTHR10366 3 275 2.9E-159 T 22-04-2016 TOLA_RS10365 a2aeca965a414ca1d6c625b4f38a3d73 354 PANTHER PTHR10366 299 353 2.9E-159 T 22-04-2016 TOLA_RS10365 a2aeca965a414ca1d6c625b4f38a3d73 354 Gene3D G3DSA:3.40.50.720 1 190 5.5E-61 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10365 a2aeca965a414ca1d6c625b4f38a3d73 354 Gene3D G3DSA:3.90.25.10 191 351 4.7E-48 T 22-04-2016 TOLA_RS06680 5931fc81f0807790a679db0f718ea4bc 98 PANTHER PTHR33178 2 96 3.5E-25 T 22-04-2016 TOLA_RS06680 5931fc81f0807790a679db0f718ea4bc 98 SMART SM00886 2 98 3.0E-31 T 22-04-2016 IPR013097 Stress responsive alpha-beta barrel TOLA_RS06680 5931fc81f0807790a679db0f718ea4bc 98 SUPERFAMILY SSF54909 1 98 1.43E-28 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel TOLA_RS06680 5931fc81f0807790a679db0f718ea4bc 98 Gene3D G3DSA:3.30.70.900 1 98 1.3E-36 T 22-04-2016 TOLA_RS06680 5931fc81f0807790a679db0f718ea4bc 98 Pfam PF07876 Stress responsive A/B Barrel Domain 2 98 1.8E-28 T 22-04-2016 IPR013097 Stress responsive alpha-beta barrel TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 PRINTS PR00127 Clp protease catalytic subunit P signature 32 47 1.1E-53 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 PRINTS PR00127 Clp protease catalytic subunit P signature 124 143 1.1E-53 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 PRINTS PR00127 Clp protease catalytic subunit P signature 103 120 1.1E-53 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 PRINTS PR00127 Clp protease catalytic subunit P signature 72 92 1.1E-53 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 PRINTS PR00127 Clp protease catalytic subunit P signature 181 200 1.1E-53 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 16 206 44.829 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 15 205 7.3E-108 T 22-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 PANTHER PTHR10381:SF22 8 207 4.4E-140 T 22-04-2016 TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 Gene3D G3DSA:3.90.226.10 16 205 9.5E-93 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 103 114 - T 22-04-2016 IPR018215 ClpP, Ser active site TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 Pfam PF00574 Clp protease 26 205 1.7E-90 T 22-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 SUPERFAMILY SSF52096 24 204 6.08E-76 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 125 138 - T 22-04-2016 IPR033135 ClpP, histidine active site TOLA_RS05545 7455ced574cfa24f542f160744b735f3 207 PANTHER PTHR10381 8 207 4.4E-140 T 22-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TOLA_RS14985 15ac6956dd50948120a83efec519f1b4 130 Gene3D G3DSA:3.30.230.10 4 130 6.6E-50 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS14985 15ac6956dd50948120a83efec519f1b4 130 PANTHER PTHR21569 1 130 4.0E-71 T 22-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TOLA_RS14985 15ac6956dd50948120a83efec519f1b4 130 SUPERFAMILY SSF54211 5 130 6.07E-47 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS14985 15ac6956dd50948120a83efec519f1b4 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 32.069 T 22-04-2016 IPR023035 Ribosomal protein S9, bacterial/plastid TOLA_RS14985 15ac6956dd50948120a83efec519f1b4 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 22-04-2016 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 TOLA_RS14985 15ac6956dd50948120a83efec519f1b4 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 4.1E-46 T 22-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TOLA_RS08345 7c1855e8ff02c60f66a52ef14e51cca0 300 Gene3D G3DSA:3.40.190.10 92 176 5.3E-25 T 22-04-2016 TOLA_RS08345 7c1855e8ff02c60f66a52ef14e51cca0 300 PANTHER PTHR30537 1 296 5.7E-113 T 22-04-2016 TOLA_RS08345 7c1855e8ff02c60f66a52ef14e51cca0 300 SUPERFAMILY SSF46785 7 112 1.18E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08345 7c1855e8ff02c60f66a52ef14e51cca0 300 PANTHER PTHR30537:SF5 1 296 5.7E-113 T 22-04-2016 TOLA_RS08345 7c1855e8ff02c60f66a52ef14e51cca0 300 SUPERFAMILY SSF53850 90 293 9.77E-47 T 22-04-2016 TOLA_RS08345 7c1855e8ff02c60f66a52ef14e51cca0 300 Gene3D G3DSA:1.10.10.10 4 80 1.6E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08345 7c1855e8ff02c60f66a52ef14e51cca0 300 Gene3D G3DSA:3.40.190.10 177 259 1.1E-4 T 22-04-2016 TOLA_RS08345 7c1855e8ff02c60f66a52ef14e51cca0 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 1.2E-14 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS08345 7c1855e8ff02c60f66a52ef14e51cca0 300 Pfam PF03466 LysR substrate binding domain 90 292 2.7E-43 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS09040 32d74d79506e863153ce5a3815d3a93a 315 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 38 310 1.5E-17 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 TOLA_RS09040 32d74d79506e863153ce5a3815d3a93a 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 283 2.6E-51 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TOLA_RS09040 32d74d79506e863153ce5a3815d3a93a 315 PANTHER PTHR10996 39 311 8.2E-90 T 22-04-2016 TOLA_RS09040 32d74d79506e863153ce5a3815d3a93a 315 SUPERFAMILY SSF52283 38 118 2.65E-20 T 22-04-2016 TOLA_RS09040 32d74d79506e863153ce5a3815d3a93a 315 Gene3D G3DSA:3.40.50.720 1 114 7.6E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09040 32d74d79506e863153ce5a3815d3a93a 315 Gene3D G3DSA:3.40.50.720 115 286 1.1E-53 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09040 32d74d79506e863153ce5a3815d3a93a 315 SUPERFAMILY SSF51735 98 284 1.08E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09040 32d74d79506e863153ce5a3815d3a93a 315 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 22-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 SUPERFAMILY SSF52096 208 285 3.78E-22 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 SUPERFAMILY SSF52096 51 177 3.78E-22 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 TIGRFAM TIGR00705 SppA_67K: signal peptide peptidase SppA, 67K type 16 608 1.4E-180 T 22-04-2016 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 PANTHER PTHR33209 1 616 3.3E-184 T 22-04-2016 TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 Gene3D G3DSA:3.90.226.10 468 548 5.8E-64 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 Gene3D G3DSA:3.90.226.10 216 312 1.2E-53 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 Gene3D G3DSA:3.90.226.10 323 431 5.8E-64 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 Gene3D G3DSA:3.90.226.10 31 173 1.2E-53 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 SUPERFAMILY SSF52096 318 439 2.07E-43 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 Pfam PF01343 Peptidase family S49 136 288 3.2E-31 T 22-04-2016 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 Pfam PF01343 Peptidase family S49 391 541 1.3E-47 T 22-04-2016 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 PANTHER PTHR33209:SF1 1 616 3.3E-184 T 22-04-2016 TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 SUPERFAMILY SSF52096 467 527 2.07E-43 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 PIRSF PIRSF001217 8 616 2.6E-198 T 22-04-2016 IPR004634 Peptidase S49, protease IV GO:0006465|GO:0008233|GO:0016021 TOLA_RS13700 683dec2a89dc79eef6284763cec9738d 616 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 338 539 5.5E-53 T 22-04-2016 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 TOLA_RS04585 d26d8a012a04b2bc7293124c10dbf272 126 PANTHER PTHR30191 1 126 1.3E-84 T 22-04-2016 TOLA_RS04585 d26d8a012a04b2bc7293124c10dbf272 126 PANTHER PTHR30191:SF5 1 126 1.3E-84 T 22-04-2016 TOLA_RS04585 d26d8a012a04b2bc7293124c10dbf272 126 ProSitePatterns PS00850 Glycine radical domain signature. 96 104 - T 22-04-2016 IPR019777 Formate C-acetyltransferase glycine radical, conserved site TOLA_RS04585 d26d8a012a04b2bc7293124c10dbf272 126 PIRSF PIRSF000378 2 126 2.8E-52 T 22-04-2016 IPR011140 Autonomous glycyl radical cofactor GrcA TOLA_RS04585 d26d8a012a04b2bc7293124c10dbf272 126 TIGRFAM TIGR04365 spare_glycyl: autonomous glycyl radical cofactor GrcA 2 126 4.9E-67 T 22-04-2016 IPR011140 Autonomous glycyl radical cofactor GrcA TOLA_RS04585 d26d8a012a04b2bc7293124c10dbf272 126 Pfam PF01228 Glycine radical 15 107 2.2E-22 T 22-04-2016 IPR001150 Glycine radical domain GO:0003824|GO:0008152 TOLA_RS04585 d26d8a012a04b2bc7293124c10dbf272 126 Gene3D G3DSA:3.20.70.20 64 125 1.0E-32 T 22-04-2016 TOLA_RS04585 d26d8a012a04b2bc7293124c10dbf272 126 SUPERFAMILY SSF51998 63 125 1.83E-23 T 22-04-2016 TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 Gene3D G3DSA:3.40.50.970 329 535 5.0E-77 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 7 334 6.1E-166 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 SUPERFAMILY SSF52922 535 665 3.27E-40 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 ProSitePatterns PS00802 Transketolase signature 2. 469 485 - T 22-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 Gene3D G3DSA:3.40.50.970 6 321 3.6E-133 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 PANTHER PTHR11624 338 665 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 PANTHER PTHR11624 1 311 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 SUPERFAMILY SSF52518 337 528 1.85E-65 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 Pfam PF02780 Transketolase, C-terminal domain 542 657 1.1E-20 T 22-04-2016 IPR033248 Transketolase, C-terminal domain TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 ProSitePatterns PS00801 Transketolase signature 1. 13 33 - T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 SMART SM00861 356 528 1.9E-65 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 TIGRFAM TIGR00232 tktlase_bact: transketolase 7 665 0.0 T 22-04-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 SUPERFAMILY SSF52518 6 321 1.15E-120 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 Pfam PF02779 Transketolase, pyrimidine binding domain 356 526 5.0E-46 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 Gene3D G3DSA:3.40.50.920 540 665 1.5E-46 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 PANTHER PTHR11624:SF1 338 665 0.0 T 22-04-2016 TOLA_RS15850 26e6f6e294399df3ee56c9908345e3e7 666 PANTHER PTHR11624:SF1 1 311 0.0 T 22-04-2016 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 121 4.5E-32 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 Gene3D G3DSA:3.40.120.10 7 138 4.8E-34 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 262 372 3.1E-25 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 PANTHER PTHR22573:SF18 7 455 3.4E-174 T 22-04-2016 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 PANTHER PTHR22573 7 455 3.4E-174 T 22-04-2016 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 SUPERFAMILY SSF53738 152 260 3.73E-25 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 153 257 1.8E-19 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 SUPERFAMILY SSF53738 262 367 2.04E-32 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 SUPERFAMILY SSF55957 372 455 2.79E-20 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 6.1E-27 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 6.1E-27 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 237 252 6.1E-27 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 169 188 6.1E-27 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 377 453 7.6E-10 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 Gene3D G3DSA:3.40.120.10 254 367 6.7E-40 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 Gene3D G3DSA:3.30.310.50 376 455 4.5E-18 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 SUPERFAMILY SSF53738 6 164 2.08E-38 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 Gene3D G3DSA:3.40.120.10 172 253 2.4E-26 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS07230 7f5f28a9128ee2856126a5fae1f95101 457 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 92 101 - T 22-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 Gene3D G3DSA:2.20.25.90 3 55 1.3E-12 T 22-04-2016 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 PANTHER PTHR11615:SF119 3 714 7.5E-197 T 22-04-2016 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 Gene3D G3DSA:2.40.40.20 528 692 2.3E-28 T 22-04-2016 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 SUPERFAMILY SSF50692 577 707 2.49E-26 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 PIRSF PIRSF036643 1 713 1.7E-138 T 22-04-2016 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 SUPERFAMILY SSF53706 3 562 7.72E-180 T 22-04-2016 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 Pfam PF04324 BFD-like [2Fe-2S] binding domain 815 864 8.1E-11 T 22-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 Gene3D G3DSA:3.40.228.10 124 307 2.8E-58 T 22-04-2016 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 Gene3D G3DSA:3.40.50.740 363 501 4.0E-69 T 22-04-2016 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 Gene3D G3DSA:3.40.50.740 308 330 4.0E-69 T 22-04-2016 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 Gene3D G3DSA:3.40.50.740 56 122 4.0E-69 T 22-04-2016 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 Pfam PF01568 Molydopterin dinucleotide binding domain 581 690 5.9E-22 T 22-04-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 Pfam PF00384 Molybdopterin oxidoreductase 63 478 2.1E-75 T 22-04-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 PANTHER PTHR11615 3 714 7.5E-197 T 22-04-2016 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 SMART SM00926 1 51 3.2E-13 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 6 24 - T 22-04-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 TOLA_RS09020 b9a35b7269a47e384e1188ab85a74b73 872 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 1 49 4.4E-12 T 22-04-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 TOLA_RS03240 b6639adc97941c86fc70c97e2ad6df89 322 Gene3D G3DSA:3.40.50.1100 133 312 7.5E-75 T 22-04-2016 TOLA_RS03240 b6639adc97941c86fc70c97e2ad6df89 322 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 299 3.0E-70 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TOLA_RS03240 b6639adc97941c86fc70c97e2ad6df89 322 Gene3D G3DSA:3.40.50.1100 36 132 3.9E-37 T 22-04-2016 TOLA_RS03240 b6639adc97941c86fc70c97e2ad6df89 322 PANTHER PTHR10314:SF110 3 319 9.0E-160 T 22-04-2016 TOLA_RS03240 b6639adc97941c86fc70c97e2ad6df89 322 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 311 1.3E-143 T 22-04-2016 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 TOLA_RS03240 b6639adc97941c86fc70c97e2ad6df89 322 TIGRFAM TIGR01136 cysKM: cysteine synthase 10 311 7.4E-136 T 22-04-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 TOLA_RS03240 b6639adc97941c86fc70c97e2ad6df89 322 SUPERFAMILY SSF53686 4 309 1.44E-96 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TOLA_RS03240 b6639adc97941c86fc70c97e2ad6df89 322 PANTHER PTHR10314 3 319 9.0E-160 T 22-04-2016 TOLA_RS03240 b6639adc97941c86fc70c97e2ad6df89 322 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 31 49 - T 22-04-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 PIRSF PIRSF000513 8 267 2.2E-93 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 Gene3D G3DSA:3.40.1190.20 10 262 1.6E-84 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 SUPERFAMILY SSF53613 11 259 2.34E-62 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 16 263 31.405 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 PANTHER PTHR20857:SF19 14 264 1.2E-85 T 22-04-2016 TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 22 29 5.6E-40 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 66 74 5.6E-40 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 122 136 5.6E-40 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 35 56 5.6E-40 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 92 109 5.6E-40 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 166 183 5.6E-40 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 Pfam PF02110 Hydroxyethylthiazole kinase family 14 257 1.0E-86 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 PANTHER PTHR20857 14 264 1.2E-85 T 22-04-2016 TOLA_RS01170 697f92c592b9ef8bd2d6444a629c7909 267 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 14 258 5.1E-84 T 22-04-2016 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 19 476 43.724 T 22-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 21 470 4.5E-178 T 22-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 SUPERFAMILY SSF51984 13 106 2.35E-28 T 22-04-2016 TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 PANTHER PTHR23135:SF5 14 465 2.4E-221 T 22-04-2016 TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 Pfam PF08245 Mur ligase middle domain 124 304 1.5E-28 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 Gene3D G3DSA:3.40.1190.10 108 325 8.6E-83 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 SUPERFAMILY SSF53244 323 472 8.06E-50 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 SUPERFAMILY SSF53623 105 321 1.31E-72 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 Gene3D G3DSA:3.40.50.720 20 107 1.7E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 Pfam PF02875 Mur ligase family, glutamate ligase domain 324 414 2.3E-23 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 Pfam PF01225 Mur ligase family, catalytic domain 21 119 4.0E-28 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 Gene3D G3DSA:3.90.190.20 326 472 6.4E-58 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS02725 ebaf609bd1b96d9cf44f73759dbc78b9 484 PANTHER PTHR23135 14 465 2.4E-221 T 22-04-2016 TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 Gene3D G3DSA:3.30.2060.10 159 231 3.0E-9 T 22-04-2016 TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 Pfam PF04851 Type III restriction enzyme, res subunit 12 119 2.5E-9 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 SUPERFAMILY SSF52540 36 80 1.81E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 SUPERFAMILY SSF52540 470 592 1.81E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 SMART SM00490 460 546 4.1E-20 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 Pfam PF12344 Ultra-violet resistance protein B 552 593 4.6E-20 T 22-04-2016 IPR024759 UvrB, YAD/RRR-motif-containing domain TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 SUPERFAMILY SSF46600 620 666 4.05E-13 T 22-04-2016 IPR001943 UVR domain GO:0005515 TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 Gene3D G3DSA:3.40.50.300 388 408 8.3E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 Gene3D G3DSA:3.40.50.300 278 338 8.3E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 Gene3D G3DSA:3.40.50.300 5 89 8.3E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 SUPERFAMILY SSF52540 3 415 1.24E-135 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 Gene3D G3DSA:3.40.50.300 420 581 1.0E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 Pfam PF00271 Helicase conserved C-terminal domain 438 545 3.8E-19 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 Pfam PF02151 UvrB/uvrC motif 631 665 6.7E-9 T 22-04-2016 IPR001943 UVR domain GO:0005515 TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 Gene3D G3DSA:4.10.860.10 612 666 3.5E-18 T 22-04-2016 IPR001943 UVR domain GO:0005515 TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 663 0.0 T 22-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 PANTHER PTHR24029 1 666 0.0 T 22-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 SMART SM00487 9 426 4.0E-27 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS05730 f425f9abb75cc6b4bad2188bdd73118e 669 Hamap MF_00204 UvrABC system protein B [uvrB]. 3 665 43.777 T 22-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 1 877 18.399 T 22-04-2016 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 133 144 - T 22-04-2016 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 533 545 - T 22-04-2016 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 Pfam PF00311 Phosphoenolpyruvate carboxylase 127 877 2.6E-284 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 PANTHER PTHR30523 1 877 0.0 T 22-04-2016 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 Gene3D G3DSA:1.20.1440.90 272 384 4.3E-31 T 22-04-2016 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 SUPERFAMILY SSF51621 5 877 0.0 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 185 201 9.0E-65 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 573 602 9.0E-65 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 132 145 9.0E-65 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 705 731 9.0E-65 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 244 259 9.0E-65 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 382 402 9.0E-65 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 531 551 9.0E-65 T 22-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TOLA_RS00485 167c99fea7cd18e831b9ac3062a1b96c 877 PANTHER PTHR30523:SF3 1 877 0.0 T 22-04-2016 TOLA_RS14765 89ee015441cdda80fbc16f4eae8e40f5 473 Gene3D G3DSA:1.10.2020.10 47 136 6.0E-43 T 22-04-2016 IPR023177 Uronate isomerase, domain 2 GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248|UniPathway: UPA00246 TOLA_RS14765 89ee015441cdda80fbc16f4eae8e40f5 473 Gene3D G3DSA:3.20.20.140 4 44 8.6E-163 T 22-04-2016 TOLA_RS14765 89ee015441cdda80fbc16f4eae8e40f5 473 Gene3D G3DSA:3.20.20.140 139 468 8.6E-163 T 22-04-2016 TOLA_RS14765 89ee015441cdda80fbc16f4eae8e40f5 473 Pfam PF02614 Glucuronate isomerase 1 466 1.4E-226 T 22-04-2016 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248|UniPathway: UPA00246 TOLA_RS14765 89ee015441cdda80fbc16f4eae8e40f5 473 Hamap MF_00675 Uronate isomerase [uxaC]. 2 468 50.939 T 22-04-2016 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248|UniPathway: UPA00246 TOLA_RS14765 89ee015441cdda80fbc16f4eae8e40f5 473 PANTHER PTHR30068 2 470 1.5E-278 T 22-04-2016 TOLA_RS14765 89ee015441cdda80fbc16f4eae8e40f5 473 PANTHER PTHR30068:SF4 2 470 1.5E-278 T 22-04-2016 TOLA_RS14765 89ee015441cdda80fbc16f4eae8e40f5 473 SUPERFAMILY SSF51556 3 467 1.53E-186 T 22-04-2016 IPR032466 Metal-dependent hydrolase TOLA_RS05395 81b51be4e00df189e8b43fcdecc371c3 641 Pfam PF08298 PrkA AAA domain 20 377 4.6E-173 T 22-04-2016 IPR013153 PrkA AAA domain TOLA_RS05395 81b51be4e00df189e8b43fcdecc371c3 641 PANTHER PTHR30267:SF2 1 641 1.7E-283 T 22-04-2016 TOLA_RS05395 81b51be4e00df189e8b43fcdecc371c3 641 PANTHER PTHR30267 1 641 1.7E-283 T 22-04-2016 TOLA_RS05395 81b51be4e00df189e8b43fcdecc371c3 641 Pfam PF06798 PrkA serine protein kinase C-terminal domain 380 633 1.8E-73 T 22-04-2016 IPR010650 PrkA C-terminal domain TOLA_RS05395 81b51be4e00df189e8b43fcdecc371c3 641 SUPERFAMILY SSF52540 250 365 4.89E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05395 81b51be4e00df189e8b43fcdecc371c3 641 SUPERFAMILY SSF52540 412 464 4.89E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05395 81b51be4e00df189e8b43fcdecc371c3 641 SUPERFAMILY SSF52540 69 147 4.89E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05395 81b51be4e00df189e8b43fcdecc371c3 641 SMART SM00763 19 377 5.0E-208 T 22-04-2016 IPR013153 PrkA AAA domain TOLA_RS05395 81b51be4e00df189e8b43fcdecc371c3 641 Gene3D G3DSA:3.40.50.300 77 143 7.3E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05395 81b51be4e00df189e8b43fcdecc371c3 641 Gene3D G3DSA:3.40.50.300 219 326 7.3E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05395 81b51be4e00df189e8b43fcdecc371c3 641 PIRSF PIRSF000549 1 641 4.9E-284 T 22-04-2016 IPR016230 Serine-protein kinase, PrkA GO:0004672 TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 4 397 2.5E-176 T 22-04-2016 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|UniPathway: UPA00868 TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 Pfam PF00364 Biotin-requiring enzyme 4 76 9.7E-17 T 22-04-2016 IPR000089 Biotin/lipoyl attachment TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 PANTHER PTHR23151 5 398 2.9E-227 T 22-04-2016 TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 Gene3D G3DSA:4.10.320.10 103 141 3.2E-14 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 SUPERFAMILY SSF52777 168 397 4.31E-92 T 22-04-2016 TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 168 396 5.6E-85 T 22-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 PANTHER PTHR23151:SF47 5 398 2.9E-227 T 22-04-2016 TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 SUPERFAMILY SSF47005 97 140 3.14E-9 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 Gene3D G3DSA:2.40.50.100 1 92 5.0E-23 T 22-04-2016 TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 SUPERFAMILY SSF51230 1 94 1.14E-22 T 22-04-2016 IPR011053 Single hybrid motif TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 Gene3D G3DSA:3.30.559.10 160 396 1.3E-95 T 22-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain TOLA_RS11310 34fa9da20428b6f2b52f8a659e71001b 398 Pfam PF02817 e3 binding domain 103 136 7.8E-11 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 TOLA_RS14605 79eadf7241dfaf2435cef0567f13d45d 82 SUPERFAMILY SSF143120 12 68 4.32E-7 T 22-04-2016 TOLA_RS14605 79eadf7241dfaf2435cef0567f13d45d 82 PANTHER PTHR33713:SF1 1 82 3.9E-38 T 22-04-2016 TOLA_RS14605 79eadf7241dfaf2435cef0567f13d45d 82 PANTHER PTHR33713 1 82 3.9E-38 T 22-04-2016 TOLA_RS14605 79eadf7241dfaf2435cef0567f13d45d 82 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 12 61 2.9E-6 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TOLA_RS14605 79eadf7241dfaf2435cef0567f13d45d 82 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 11 72 7.0E-8 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TOLA_RS02615 b5688c6fa50532b2c21e46fe732bb556 410 Gene3D G3DSA:2.70.70.10 264 409 8.9E-37 T 22-04-2016 TOLA_RS02615 b5688c6fa50532b2c21e46fe732bb556 410 PANTHER PTHR21666 29 404 1.9E-88 T 22-04-2016 TOLA_RS02615 b5688c6fa50532b2c21e46fe732bb556 410 SUPERFAMILY SSF51261 189 408 3.71E-44 T 22-04-2016 IPR011055 Duplicated hybrid motif TOLA_RS02615 b5688c6fa50532b2c21e46fe732bb556 410 PANTHER PTHR21666:SF213 29 404 1.9E-88 T 22-04-2016 TOLA_RS02615 b5688c6fa50532b2c21e46fe732bb556 410 Pfam PF01551 Peptidase family M23 311 404 1.9E-25 T 22-04-2016 IPR016047 Peptidase M23 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 2.6E-88 T 22-04-2016 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 SUPERFAMILY SSF64484 1159 1402 0.0 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 SUPERFAMILY SSF64484 16 970 0.0 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 Pfam PF00623 RNA polymerase Rpb1, domain 2 389 485 3.1E-26 T 22-04-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 394 8.5E-8 T 22-04-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 Gene3D G3DSA:2.40.40.20 349 376 7.6E-37 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 Gene3D G3DSA:2.40.40.20 417 489 7.6E-37 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 670 1.6E-26 T 22-04-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 PANTHER PTHR19376:SF32 989 1183 0.0 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 PANTHER PTHR19376:SF32 570 969 0.0 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 PANTHER PTHR19376 989 1183 0.0 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 PANTHER PTHR19376:SF32 1203 1288 0.0 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 PANTHER PTHR19376:SF32 4 551 0.0 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 Pfam PF04998 RNA polymerase Rpb1, domain 5 792 1342 7.5E-77 T 22-04-2016 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 SMART SM00663 235 514 7.6E-183 T 22-04-2016 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 15 1401 10.437 T 22-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 Pfam PF05000 RNA polymerase Rpb1, domain 4 700 778 8.3E-19 T 22-04-2016 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 PANTHER PTHR19376 1203 1288 0.0 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 PANTHER PTHR19376 570 969 0.0 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 PANTHER PTHR19376 4 551 0.0 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 PANTHER PTHR19376 1329 1420 0.0 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 20 1392 0.0 T 22-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 PANTHER PTHR19376:SF32 1329 1420 0.0 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 Gene3D G3DSA:2.40.50.100 1182 1236 2.8E-7 T 22-04-2016 TOLA_RS14245 ea5f0f6f1b0c8f0e645304d1ff698c3a 1434 Gene3D G3DSA:2.40.50.100 1004 1042 4.3E-4 T 22-04-2016 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 652 695 3.6E-19 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 SUPERFAMILY SSF50447 454 551 4.28E-20 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 7 853 0.0 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 PANTHER PTHR11777:SF9 1 874 0.0 T 22-04-2016 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 SUPERFAMILY SSF55186 551 708 8.11E-51 T 22-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 Pfam PF02272 DHHA1 domain 799 867 9.4E-16 T 22-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 Gene3D G3DSA:3.30.930.10 2 250 2.5E-122 T 22-04-2016 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 PANTHER PTHR11777 1 874 0.0 T 22-04-2016 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 874 197.256 T 22-04-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 Pfam PF01411 tRNA synthetases class II (A) 7 554 7.2E-226 T 22-04-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 SMART SM00863 652 695 8.4E-23 T 22-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 280 296 2.5E-32 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 304 317 2.5E-32 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 234 247 2.5E-32 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 76 87 2.5E-32 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 207 218 2.5E-32 T 22-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 SUPERFAMILY SSF55681 3 253 5.47E-106 T 22-04-2016 TOLA_RS13950 7b558d530a2814aabae5410f43807323 874 SUPERFAMILY SSF101353 254 463 1.7E-59 T 22-04-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7|Reactome: REACT_71 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 330 344 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 614 6.2E-270 T 22-04-2016 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 PRINTS PR00301 70kDa heat shock protein signature 20 33 8.3E-58 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 PRINTS PR00301 70kDa heat shock protein signature 209 219 8.3E-58 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 PRINTS PR00301 70kDa heat shock protein signature 48 60 8.3E-58 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 PRINTS PR00301 70kDa heat shock protein signature 358 378 8.3E-58 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 PRINTS PR00301 70kDa heat shock protein signature 150 170 8.3E-58 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 PRINTS PR00301 70kDa heat shock protein signature 327 343 8.3E-58 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 PRINTS PR00301 70kDa heat shock protein signature 383 402 8.3E-58 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 PRINTS PR00301 70kDa heat shock protein signature 464 480 8.3E-58 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 PRINTS PR00301 70kDa heat shock protein signature 70 78 8.3E-58 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 Gene3D G3DSA:3.30.420.40 312 354 1.4E-31 T 22-04-2016 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 Gene3D G3DSA:3.30.420.40 204 236 1.4E-31 T 22-04-2016 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 PANTHER PTHR19375:SF176 19 604 0.0 T 22-04-2016 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 Gene3D G3DSA:3.30.30.30 64 98 4.8E-6 T 22-04-2016 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 Gene3D G3DSA:3.30.420.40 12 48 1.5E-50 T 22-04-2016 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 Gene3D G3DSA:3.30.420.40 113 203 1.5E-50 T 22-04-2016 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 SUPERFAMILY SSF53067 198 375 8.87E-48 T 22-04-2016 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 Gene3D G3DSA:1.20.1270.10 527 614 1.9E-33 T 22-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 SUPERFAMILY SSF100920 382 535 5.49E-50 T 22-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 Gene3D G3DSA:2.60.34.10 385 526 2.2E-53 T 22-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 615 44.693 T 22-04-2016 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 203 216 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 SUPERFAMILY SSF53067 19 194 6.31E-51 T 22-04-2016 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 SUPERFAMILY SSF100934 502 614 2.75E-35 T 22-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 PANTHER PTHR19375 19 604 0.0 T 22-04-2016 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 Gene3D G3DSA:3.90.640.10 237 307 8.3E-6 T 22-04-2016 TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site TOLA_RS10245 4798c966c436d059ef83c6ed4dd4c684 616 Pfam PF00012 Hsp70 protein 21 598 2.5E-190 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS10455 f05a68b8cefb242cba94038b4c555154 112 Gene3D G3DSA:3.30.460.10 5 103 5.7E-25 T 22-04-2016 TOLA_RS10455 f05a68b8cefb242cba94038b4c555154 112 PANTHER PTHR33571 11 104 3.9E-12 T 22-04-2016 TOLA_RS10455 f05a68b8cefb242cba94038b4c555154 112 Pfam PF01909 Nucleotidyltransferase domain 15 90 1.1E-11 T 22-04-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TOLA_RS10455 f05a68b8cefb242cba94038b4c555154 112 SUPERFAMILY SSF81301 11 96 2.52E-18 T 22-04-2016 TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.0E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.0E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.0E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PANTHER PTHR24322 15 142 3.9E-60 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PANTHER PTHR24322 158 190 3.9E-60 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 SUPERFAMILY SSF51735 6 252 6.62E-77 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 7.0E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 7.0E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.0E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 7.0E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 7.0E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 7.0E-41 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PANTHER PTHR24322:SF402 15 142 3.9E-60 T 22-04-2016 TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 PANTHER PTHR24322:SF402 158 190 3.9E-60 T 22-04-2016 TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 Gene3D G3DSA:3.40.50.720 6 252 4.1E-82 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 250 8.3E-59 T 22-04-2016 TOLA_RS15655 11e9240eb8ddd710019aa044341b7e74 253 TIGRFAM TIGR01832 kduD: 2-deoxy-D-gluconate 3-dehydrogenase 6 253 4.1E-133 T 22-04-2016 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase GO:0008678|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.12+1.1.1.127|MetaCyc: PWY-5515|MetaCyc: PWY-6507|MetaCyc: PWY-7562 TOLA_RS08695 1ef240f0aea307075c9a95933ffb11a7 280 Gene3D G3DSA:1.10.3720.10 13 267 2.5E-55 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08695 1ef240f0aea307075c9a95933ffb11a7 280 PANTHER PTHR32243 2 280 2.1E-81 T 22-04-2016 TOLA_RS08695 1ef240f0aea307075c9a95933ffb11a7 280 SUPERFAMILY SSF161098 14 279 4.02E-63 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08695 1ef240f0aea307075c9a95933ffb11a7 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 272 2.8E-22 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS01925 3401b2d255abecf6600b03da43623774 406 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 404 4.3E-164 T 22-04-2016 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 TOLA_RS01925 3401b2d255abecf6600b03da43623774 406 PANTHER PTHR30012:SF6 2 405 5.0E-231 T 22-04-2016 TOLA_RS01925 3401b2d255abecf6600b03da43623774 406 Pfam PF00482 Type II secretion system (T2SS), protein F 72 194 2.5E-30 T 22-04-2016 IPR018076 Type II secretion system F domain TOLA_RS01925 3401b2d255abecf6600b03da43623774 406 Pfam PF00482 Type II secretion system (T2SS), protein F 274 395 2.9E-26 T 22-04-2016 IPR018076 Type II secretion system F domain TOLA_RS01925 3401b2d255abecf6600b03da43623774 406 PANTHER PTHR30012 2 405 5.0E-231 T 22-04-2016 TOLA_RS01925 3401b2d255abecf6600b03da43623774 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 385 404 3.3E-41 T 22-04-2016 IPR003004 GspF/PilC family TOLA_RS01925 3401b2d255abecf6600b03da43623774 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 67 79 3.3E-41 T 22-04-2016 IPR003004 GspF/PilC family TOLA_RS01925 3401b2d255abecf6600b03da43623774 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 166 194 3.3E-41 T 22-04-2016 IPR003004 GspF/PilC family TOLA_RS01925 3401b2d255abecf6600b03da43623774 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 369 383 3.3E-41 T 22-04-2016 IPR003004 GspF/PilC family TOLA_RS01925 3401b2d255abecf6600b03da43623774 406 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 166 194 - T 22-04-2016 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 TOLA_RS12745 622692cfc7640d3b4c188f29ad93628c 88 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 10 70 15.884 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TOLA_RS12745 622692cfc7640d3b4c188f29ad93628c 88 SUPERFAMILY SSF116842 2 73 3.4E-22 T 22-04-2016 TOLA_RS12745 622692cfc7640d3b4c188f29ad93628c 88 PANTHER PTHR34137 1 84 2.0E-24 T 22-04-2016 TOLA_RS12745 622692cfc7640d3b4c188f29ad93628c 88 Gene3D G3DSA:1.10.287.1040 5 76 9.0E-27 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TOLA_RS12745 622692cfc7640d3b4c188f29ad93628c 88 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 10 66 6.0E-23 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TOLA_RS12745 622692cfc7640d3b4c188f29ad93628c 88 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 51 2.0E-12 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TOLA_RS12745 622692cfc7640d3b4c188f29ad93628c 88 Pfam PF02609 Exonuclease VII small subunit 11 62 9.2E-20 T 22-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TOLA_RS07575 2f76d16eeeb9e2f1cdd7d0cca17f96e3 300 Pfam PF01497 Periplasmic binding protein 37 269 1.4E-23 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 TOLA_RS07575 2f76d16eeeb9e2f1cdd7d0cca17f96e3 300 PANTHER PTHR30532:SF1 35 299 7.5E-46 T 22-04-2016 TOLA_RS07575 2f76d16eeeb9e2f1cdd7d0cca17f96e3 300 SUPERFAMILY SSF53807 35 290 1.14E-52 T 22-04-2016 TOLA_RS07575 2f76d16eeeb9e2f1cdd7d0cca17f96e3 300 Gene3D G3DSA:3.40.50.1980 33 118 1.2E-27 T 22-04-2016 TOLA_RS07575 2f76d16eeeb9e2f1cdd7d0cca17f96e3 300 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 53 71 6.9E-22 T 22-04-2016 IPR008091 Ferrichrome-binding periplasmic protein TOLA_RS07575 2f76d16eeeb9e2f1cdd7d0cca17f96e3 300 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 84 99 6.9E-22 T 22-04-2016 IPR008091 Ferrichrome-binding periplasmic protein TOLA_RS07575 2f76d16eeeb9e2f1cdd7d0cca17f96e3 300 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 271 284 6.9E-22 T 22-04-2016 IPR008091 Ferrichrome-binding periplasmic protein TOLA_RS07575 2f76d16eeeb9e2f1cdd7d0cca17f96e3 300 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 182 197 6.9E-22 T 22-04-2016 IPR008091 Ferrichrome-binding periplasmic protein TOLA_RS07575 2f76d16eeeb9e2f1cdd7d0cca17f96e3 300 PRINTS PR01715 Ferrichrome-binding periplasmic protein signature 206 224 6.9E-22 T 22-04-2016 IPR008091 Ferrichrome-binding periplasmic protein TOLA_RS07575 2f76d16eeeb9e2f1cdd7d0cca17f96e3 300 Gene3D G3DSA:3.40.50.1980 123 292 4.0E-53 T 22-04-2016 TOLA_RS07575 2f76d16eeeb9e2f1cdd7d0cca17f96e3 300 PANTHER PTHR30532 35 299 7.5E-46 T 22-04-2016 TOLA_RS12810 979e5c9488f28ec53e782fa1bd3f9f77 244 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 13 36 8.5E-8 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS12810 979e5c9488f28ec53e782fa1bd3f9f77 244 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 15 36 7.1E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS12810 979e5c9488f28ec53e782fa1bd3f9f77 244 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 15 35 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS12810 979e5c9488f28ec53e782fa1bd3f9f77 244 SUPERFAMILY SSF54523 17 130 7.38E-5 T 22-04-2016 TOLA_RS08705 bcf6cb4bb9f70444212921d3603a4b15 365 Gene3D G3DSA:2.40.50.140 286 345 2.3E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS08705 bcf6cb4bb9f70444212921d3603a4b15 365 PANTHER PTHR24220 301 344 3.0E-142 T 22-04-2016 TOLA_RS08705 bcf6cb4bb9f70444212921d3603a4b15 365 PANTHER PTHR24220 6 267 3.0E-142 T 22-04-2016 TOLA_RS08705 bcf6cb4bb9f70444212921d3603a4b15 365 PANTHER PTHR24220:SF151 301 344 3.0E-142 T 22-04-2016 TOLA_RS08705 bcf6cb4bb9f70444212921d3603a4b15 365 PANTHER PTHR24220:SF151 6 267 3.0E-142 T 22-04-2016 TOLA_RS08705 bcf6cb4bb9f70444212921d3603a4b15 365 Gene3D G3DSA:3.40.50.300 3 234 1.4E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08705 bcf6cb4bb9f70444212921d3603a4b15 365 Pfam PF08402 TOBE domain 283 354 4.2E-11 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 TOLA_RS08705 bcf6cb4bb9f70444212921d3603a4b15 365 SMART SM00382 29 212 2.1E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS08705 bcf6cb4bb9f70444212921d3603a4b15 365 Pfam PF00005 ABC transporter 20 162 3.0E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS08705 bcf6cb4bb9f70444212921d3603a4b15 365 SUPERFAMILY SSF50331 237 358 3.97E-21 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS08705 bcf6cb4bb9f70444212921d3603a4b15 365 SUPERFAMILY SSF52540 5 244 1.1E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08705 bcf6cb4bb9f70444212921d3603a4b15 365 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS11715 8306bbdf1b66187d4b3715cd34cfcbf0 217 PANTHER PTHR10683:SF15 1 216 9.8E-101 T 22-04-2016 TOLA_RS11715 8306bbdf1b66187d4b3715cd34cfcbf0 217 ProSitePatterns PS00958 Transaldolase active site. 82 99 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS11715 8306bbdf1b66187d4b3715cd34cfcbf0 217 PANTHER PTHR10683 1 216 9.8E-101 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS11715 8306bbdf1b66187d4b3715cd34cfcbf0 217 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 215 4.2E-81 T 22-04-2016 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS11715 8306bbdf1b66187d4b3715cd34cfcbf0 217 Gene3D G3DSA:3.20.20.70 1 214 5.8E-61 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS11715 8306bbdf1b66187d4b3715cd34cfcbf0 217 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS11715 8306bbdf1b66187d4b3715cd34cfcbf0 217 SUPERFAMILY SSF51569 1 215 2.09E-64 T 22-04-2016 TOLA_RS11715 8306bbdf1b66187d4b3715cd34cfcbf0 217 Pfam PF00923 Transaldolase 4 206 1.5E-44 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS08325 27fe85482521e0427faa7bbf0250006d 403 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 206 220 - T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS08325 27fe85482521e0427faa7bbf0250006d 403 PANTHER PTHR11808 7 399 2.9E-115 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS08325 27fe85482521e0427faa7bbf0250006d 403 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 400 1.2E-103 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS08325 27fe85482521e0427faa7bbf0250006d 403 Gene3D G3DSA:3.90.1150.10 266 400 1.3E-38 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS08325 27fe85482521e0427faa7bbf0250006d 403 Gene3D G3DSA:3.40.640.10 11 263 1.1E-75 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS08325 27fe85482521e0427faa7bbf0250006d 403 SUPERFAMILY SSF53383 50 399 2.99E-90 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS08325 27fe85482521e0427faa7bbf0250006d 403 PIRSF PIRSF001434 1 403 4.8E-120 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 SMART SM00487 292 510 4.4E-6 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 Pfam PF11867 Domain of unknown function (DUF3387) 730 1070 8.9E-113 T 22-04-2016 IPR021810 Protein of unknown function DUF3387 TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 PANTHER PTHR30195:SF15 455 1018 6.0E-255 T 22-04-2016 TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 PANTHER PTHR30195:SF15 308 432 6.0E-255 T 22-04-2016 TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 PANTHER PTHR30195:SF15 3 287 6.0E-255 T 22-04-2016 TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 5 732 2.3E-193 T 22-04-2016 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 SUPERFAMILY SSF52540 634 713 2.04E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 SUPERFAMILY SSF52540 565 604 2.04E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 SUPERFAMILY SSF52540 421 509 2.04E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 Gene3D G3DSA:3.40.50.300 271 485 3.7E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 PANTHER PTHR30195 455 1018 6.0E-255 T 22-04-2016 TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 PANTHER PTHR30195 308 432 6.0E-255 T 22-04-2016 TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 PANTHER PTHR30195 3 287 6.0E-255 T 22-04-2016 TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 2 212 7.6E-44 T 22-04-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 Pfam PF04851 Type III restriction enzyme, res subunit 294 477 1.0E-14 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TOLA_RS06255 5c153980bd59605e4246b8ab822874d9 1074 SUPERFAMILY SSF52540 229 530 1.2E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05790 cbde931663e166405b45112de428a85b 507 Pfam PF06804 NlpB/DapX lipoprotein 39 355 1.3E-81 T 22-04-2016 IPR010653 NlpB/DapX lipoprotein TOLA_RS05790 cbde931663e166405b45112de428a85b 507 Pfam PF06804 NlpB/DapX lipoprotein 363 501 5.4E-14 T 22-04-2016 IPR010653 NlpB/DapX lipoprotein TOLA_RS05605 8e78d6c1c17fe67344478a8544b738e6 339 SUPERFAMILY SSF53850 91 303 9.77E-33 T 22-04-2016 TOLA_RS05605 8e78d6c1c17fe67344478a8544b738e6 339 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.5E-9 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS05605 8e78d6c1c17fe67344478a8544b738e6 339 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.5E-9 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS05605 8e78d6c1c17fe67344478a8544b738e6 339 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.5E-9 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS05605 8e78d6c1c17fe67344478a8544b738e6 339 SUPERFAMILY SSF46785 10 113 4.3E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05605 8e78d6c1c17fe67344478a8544b738e6 339 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 3.6E-19 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS05605 8e78d6c1c17fe67344478a8544b738e6 339 Gene3D G3DSA:3.40.190.10 95 179 2.5E-22 T 22-04-2016 TOLA_RS05605 8e78d6c1c17fe67344478a8544b738e6 339 PANTHER PTHR30537:SF26 3 317 9.0E-81 T 22-04-2016 TOLA_RS05605 8e78d6c1c17fe67344478a8544b738e6 339 Gene3D G3DSA:3.40.190.10 180 265 9.0E-14 T 22-04-2016 TOLA_RS05605 8e78d6c1c17fe67344478a8544b738e6 339 Pfam PF03466 LysR substrate binding domain 91 299 8.2E-28 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS05605 8e78d6c1c17fe67344478a8544b738e6 339 PANTHER PTHR30537 3 317 9.0E-81 T 22-04-2016 TOLA_RS05605 8e78d6c1c17fe67344478a8544b738e6 339 Gene3D G3DSA:1.10.10.10 7 87 2.2E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 SUPERFAMILY SSF82693 673 722 2.46E-27 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 SUPERFAMILY SSF82693 809 857 2.46E-27 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 PANTHER PTHR32063:SF13 1 1032 0.0 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 SUPERFAMILY SSF82693 566 671 3.45E-32 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 SUPERFAMILY SSF82866 297 497 3.66E-48 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 SUPERFAMILY SSF82693 135 182 7.32E-27 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 SUPERFAMILY SSF82693 274 330 7.32E-27 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 2.5E-112 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 2.5E-112 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 2.5E-112 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 2.5E-112 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 2.5E-112 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 2.5E-112 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 2.5E-112 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 2.5E-112 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 2.5E-112 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 Gene3D G3DSA:3.30.70.1430 38 139 1.9E-33 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 Gene3D G3DSA:3.30.2090.10 181 275 1.3E-28 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 Gene3D G3DSA:3.30.2090.10 722 811 2.6E-27 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 SUPERFAMILY SSF82714 723 810 9.42E-22 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 Gene3D G3DSA:1.10.3850.10 815 1028 6.4E-56 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 Gene3D G3DSA:1.10.3850.10 279 498 8.1E-59 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 SUPERFAMILY SSF82693 38 131 1.74E-26 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 PANTHER PTHR32063 1 1032 0.0 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 SUPERFAMILY SSF82714 182 272 6.41E-23 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1046 0.0 T 22-04-2016 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 SUPERFAMILY SSF82866 833 1027 8.89E-44 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 Gene3D G3DSA:3.30.70.1430 568 671 8.7E-39 T 22-04-2016 TOLA_RS01865 ba4b19ece4718f032a054d7429863c4e 1048 Pfam PF00873 AcrB/AcrD/AcrF family 1 1026 0.0 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 PRINTS PR00987 Glutamyl-tRNA synthetase signature 183 191 4.8E-14 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 4.8E-14 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 4.8E-14 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 4.8E-14 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 PRINTS PR00987 Glutamyl-tRNA synthetase signature 167 177 4.8E-14 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 Gene3D G3DSA:3.90.800.10 69 167 4.6E-18 T 22-04-2016 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 Gene3D G3DSA:3.40.50.620 169 217 6.3E-40 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 Gene3D G3DSA:3.40.50.620 3 68 6.3E-40 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 3 287 41.787 T 22-04-2016 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 SUPERFAMILY SSF52374 3 284 1.04E-88 T 22-04-2016 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 PANTHER PTHR11451:SF35 1 218 1.2E-110 T 22-04-2016 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 117 234 4.9E-20 T 22-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 106 8.8E-27 T 22-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 PANTHER PTHR11451 1 218 1.2E-110 T 22-04-2016 TOLA_RS11655 28fa1ebd985bf490029c3263a1135dc4 289 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 3 267 1.9E-112 T 22-04-2016 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 TOLA_RS06180 ac3b139745a4dccf8db6839331d43822 282 PANTHER PTHR13754:SF13 4 277 2.1E-62 T 22-04-2016 TOLA_RS06180 ac3b139745a4dccf8db6839331d43822 282 Gene3D G3DSA:3.60.15.10 6 268 3.5E-35 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS06180 ac3b139745a4dccf8db6839331d43822 282 Pfam PF00753 Metallo-beta-lactamase superfamily 24 92 3.3E-12 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS06180 ac3b139745a4dccf8db6839331d43822 282 SUPERFAMILY SSF56281 3 105 1.4E-35 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS06180 ac3b139745a4dccf8db6839331d43822 282 SUPERFAMILY SSF56281 139 258 1.4E-35 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS06180 ac3b139745a4dccf8db6839331d43822 282 PANTHER PTHR13754 4 277 2.1E-62 T 22-04-2016 TOLA_RS06180 ac3b139745a4dccf8db6839331d43822 282 SMART SM00849 23 249 8.0E-5 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS00570 3db42abfcc493c23f6dbb51a3cbad06d 122 SMART SM01374 1 122 6.5E-87 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TOLA_RS00570 3db42abfcc493c23f6dbb51a3cbad06d 122 PANTHER PTHR11761 1 122 2.2E-77 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TOLA_RS00570 3db42abfcc493c23f6dbb51a3cbad06d 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 22-04-2016 IPR019972 Ribosomal protein L14P, conserved site TOLA_RS00570 3db42abfcc493c23f6dbb51a3cbad06d 122 SUPERFAMILY SSF50193 1 122 2.22E-52 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TOLA_RS00570 3db42abfcc493c23f6dbb51a3cbad06d 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 6.0E-59 T 22-04-2016 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 TOLA_RS00570 3db42abfcc493c23f6dbb51a3cbad06d 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.517 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TOLA_RS00570 3db42abfcc493c23f6dbb51a3cbad06d 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 5.6E-56 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TOLA_RS00570 3db42abfcc493c23f6dbb51a3cbad06d 122 Gene3D G3DSA:2.40.150.20 1 122 1.9E-56 T 22-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 PANTHER PTHR24031:SF249 256 279 1.3E-124 T 22-04-2016 TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 PANTHER PTHR24031:SF249 296 599 1.3E-124 T 22-04-2016 TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 PANTHER PTHR24031:SF249 622 685 1.3E-124 T 22-04-2016 TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 Pfam PF00270 DEAD/DEAH box helicase 287 404 5.8E-21 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 Gene3D G3DSA:1.10.150.20 3 33 9.2E-5 T 22-04-2016 TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 Gene3D G3DSA:3.40.50.300 253 450 2.3E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 SUPERFAMILY SSF50249 6 171 1.49E-37 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 26 660 6.5E-234 T 22-04-2016 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 Pfam PF17191 RecG wedge domain 8 169 2.7E-21 T 22-04-2016 IPR033454 RecG, wedge domain TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 SMART SM00490 501 585 1.2E-22 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 SUPERFAMILY SSF52540 205 450 3.27E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 Gene3D G3DSA:2.40.50.140 44 138 2.9E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 SMART SM00487 262 456 1.9E-31 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 Gene3D G3DSA:3.40.50.300 451 633 2.4E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 Pfam PF00271 Helicase conserved C-terminal domain 476 584 7.9E-18 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 PANTHER PTHR24031 256 279 1.3E-124 T 22-04-2016 TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 PANTHER PTHR24031 296 599 1.3E-124 T 22-04-2016 TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 PANTHER PTHR24031 622 685 1.3E-124 T 22-04-2016 TOLA_RS01280 b47b25ab679df9e30327b64e852bc62c 689 SUPERFAMILY SSF52540 449 650 1.47E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11135 996873a5eb528a734506705d6ab38bf8 311 SUPERFAMILY SSF52151 4 122 2.88E-81 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 TOLA_RS11135 996873a5eb528a734506705d6ab38bf8 311 SUPERFAMILY SSF52151 190 308 2.88E-81 T 22-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 TOLA_RS11135 996873a5eb528a734506705d6ab38bf8 311 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 290 1.3E-121 T 22-04-2016 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 TOLA_RS11135 996873a5eb528a734506705d6ab38bf8 311 PIRSF PIRSF000446 1 311 5.3E-129 T 22-04-2016 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388|UniPathway: UPA00094 TOLA_RS11135 996873a5eb528a734506705d6ab38bf8 311 Gene3D G3DSA:3.30.70.250 125 196 8.4E-31 T 22-04-2016 TOLA_RS11135 996873a5eb528a734506705d6ab38bf8 311 Gene3D G3DSA:3.40.366.10 197 305 1.0E-72 T 22-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 TOLA_RS11135 996873a5eb528a734506705d6ab38bf8 311 Gene3D G3DSA:3.40.366.10 3 122 1.0E-72 T 22-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 TOLA_RS11135 996873a5eb528a734506705d6ab38bf8 311 Pfam PF00698 Acyl transferase domain 8 298 1.5E-38 T 22-04-2016 IPR014043 Acyl transferase TOLA_RS11135 996873a5eb528a734506705d6ab38bf8 311 PANTHER PTHR10982 1 311 1.8E-157 T 22-04-2016 TOLA_RS11135 996873a5eb528a734506705d6ab38bf8 311 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 307 1.3E-40 T 22-04-2016 IPR020801 Polyketide synthase, acyl transferase domain TOLA_RS11135 996873a5eb528a734506705d6ab38bf8 311 SUPERFAMILY SSF55048 130 197 3.01E-16 T 22-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 PANTHER PTHR13789:SF233 17 401 2.3E-174 T 22-04-2016 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 Gene3D G3DSA:3.50.50.60 16 194 7.3E-46 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 Gene3D G3DSA:3.50.50.60 279 364 7.3E-46 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 305 318 - T 22-04-2016 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 UniPathway: UPA00232 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 168 183 9.1E-21 T 22-04-2016 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 18 40 9.1E-21 T 22-04-2016 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 9.1E-21 T 22-04-2016 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 9.1E-21 T 22-04-2016 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 Pfam PF01494 FAD binding domain 18 348 1.5E-29 T 22-04-2016 IPR002938 FAD-binding domain GO:0071949 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 PANTHER PTHR13789 17 401 2.3E-174 T 22-04-2016 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 18 400 1.5E-117 T 22-04-2016 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 UniPathway: UPA00232 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 SUPERFAMILY SSF51905 16 189 8.75E-58 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04035 a4e2573d64b4cb574a093e0f6f03b513 401 SUPERFAMILY SSF51905 278 393 8.75E-58 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS13125 c238e69dfcf511fb257a8d66f0801d68 256 PANTHER PTHR30502:SF4 1 255 5.5E-158 T 22-04-2016 TOLA_RS13125 c238e69dfcf511fb257a8d66f0801d68 256 Gene3D G3DSA:3.20.20.60 3 254 2.5E-80 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS13125 c238e69dfcf511fb257a8d66f0801d68 256 Hamap MF_01291 5-keto-4-deoxy-D-glucarate aldolase [garL]. 1 256 68.656 T 22-04-2016 IPR017648 5-keto-4-deoxy-D-glucarate aldolase GO:0008672|GO:0019394 KEGG: 00053+4.1.2.20|UniPathway: UPA00565 TOLA_RS13125 c238e69dfcf511fb257a8d66f0801d68 256 PANTHER PTHR30502 1 255 5.5E-158 T 22-04-2016 TOLA_RS13125 c238e69dfcf511fb257a8d66f0801d68 256 TIGRFAM TIGR03239 GarL: 2-dehydro-3-deoxyglucarate aldolase 8 256 4.9E-140 T 22-04-2016 IPR017648 5-keto-4-deoxy-D-glucarate aldolase GO:0008672|GO:0019394 KEGG: 00053+4.1.2.20|UniPathway: UPA00565 TOLA_RS13125 c238e69dfcf511fb257a8d66f0801d68 256 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 20 244 1.3E-57 T 22-04-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 TOLA_RS13125 c238e69dfcf511fb257a8d66f0801d68 256 SUPERFAMILY SSF51621 3 255 5.65E-81 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 Pfam PF00690 Cation transporter/ATPase, N-terminus 11 78 7.9E-22 T 22-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 Pfam PF00122 E1-E2 ATPase 89 322 3.5E-62 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 Pfam PF00689 Cation transporting ATPase, C-terminus 729 900 6.6E-39 T 22-04-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 PANTHER PTHR24093 6 804 3.2E-297 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 PANTHER PTHR24093 839 911 3.2E-297 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 613 734 2.7E-29 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 352 4.7E-41 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 SUPERFAMILY SSF81653 122 229 1.7E-29 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 SUPERFAMILY SSF56784 329 349 1.01E-56 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 SUPERFAMILY SSF56784 492 746 1.01E-56 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 Gene3D G3DSA:1.20.1110.10 62 115 5.9E-102 T 22-04-2016 IPR023298 P-type ATPase, transmembrane domain TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 Gene3D G3DSA:1.20.1110.10 613 901 5.9E-102 T 22-04-2016 IPR023298 P-type ATPase, transmembrane domain TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 SMART SM00831 10 83 1.2E-29 T 22-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 Pfam PF00702 haloacid dehalogenase-like hydrolase 328 658 2.9E-23 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 SUPERFAMILY SSF81665 10 121 9.68E-120 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 SUPERFAMILY SSF81665 694 905 9.68E-120 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 SUPERFAMILY SSF81665 231 325 9.68E-120 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 668 680 3.6E-39 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 644 663 3.6E-39 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 331 345 3.6E-39 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 168 182 3.6E-39 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 575 3.6E-39 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 543 554 3.6E-39 T 22-04-2016 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 495 513 1.9E-17 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 616 632 1.9E-17 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 644 660 1.9E-17 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 676 701 1.9E-17 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 333 339 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 Gene3D G3DSA:3.40.1110.10 321 550 5.1E-54 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 Gene3D G3DSA:2.70.150.10 26 61 5.3E-40 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 Gene3D G3DSA:2.70.150.10 116 229 5.3E-40 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS09050 d909401f00f1620221b9dc1420fd0f69 912 SUPERFAMILY SSF81660 338 547 1.44E-47 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 SUPERFAMILY SSF55021 278 375 1.22E-23 T 22-04-2016 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 Pfam PF00800 Prephenate dehydratase 104 285 1.2E-52 T 22-04-2016 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 Gene3D G3DSA:1.20.59.10 3 103 7.4E-36 T 22-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 259 281 - T 22-04-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 PIRSF PIRSF001500 1 378 1.4E-120 T 22-04-2016 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 SMART SM00830 8 88 2.5E-23 T 22-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 TIGRFAM TIGR01797 CM_P_1: chorismate mutase 5 86 4.8E-25 T 22-04-2016 IPR010952 Chorismate mutase, gammaproteobacteria GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626|UniPathway: UPA00120|UniPathway: UPA00121 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 Gene3D G3DSA:3.30.70.260 293 376 2.8E-26 T 22-04-2016 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 SUPERFAMILY SSF48600 3 89 1.06E-21 T 22-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 PANTHER PTHR21022:SF0 4 376 1.1E-127 T 22-04-2016 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 SUPERFAMILY SSF53850 103 288 8.03E-51 T 22-04-2016 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 Gene3D G3DSA:3.40.190.10 104 190 4.2E-30 T 22-04-2016 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 PANTHER PTHR21022 4 376 1.1E-127 T 22-04-2016 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 Pfam PF01817 Chorismate mutase type II 8 86 2.3E-16 T 22-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 Gene3D G3DSA:3.40.190.10 191 271 2.0E-18 T 22-04-2016 TOLA_RS07855 a1a662a27df00d4f3254317d6373668d 387 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 323 330 - T 22-04-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 TOLA_RS04420 adbcd84399c0e52aec83e8f99300a02c 170 Gene3D G3DSA:1.20.1380.10 61 169 7.5E-44 T 22-04-2016 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 TOLA_RS04420 adbcd84399c0e52aec83e8f99300a02c 170 Gene3D G3DSA:1.10.1220.10 1 38 3.8E-23 T 22-04-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TOLA_RS04420 adbcd84399c0e52aec83e8f99300a02c 170 Pfam PF03925 SeqA protein C-terminal domain 62 168 1.1E-41 T 22-04-2016 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 TOLA_RS04420 adbcd84399c0e52aec83e8f99300a02c 170 SUPERFAMILY SSF47598 1 34 4.67E-12 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 TOLA_RS04420 adbcd84399c0e52aec83e8f99300a02c 170 SUPERFAMILY SSF82808 61 168 8.63E-40 T 22-04-2016 IPR026577 Replication modulator SeqA, C-terminal DNA-binding domain GO:0003677 TOLA_RS04420 adbcd84399c0e52aec83e8f99300a02c 170 Hamap MF_00908 Negative modulator of initiation of replication [seqA]. 1 170 38.437 T 22-04-2016 IPR005621 Negative modulator of initiation of replicationr SeqA GO:0003677|GO:0032297 TOLA_RS12610 951e78df51c45d3f2403f79d6afedee5 792 SUPERFAMILY SSF52518 399 607 2.0E-6 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS12610 951e78df51c45d3f2403f79d6afedee5 792 Pfam PF09364 XFP N-terminal domain 63 333 1.0E-10 T 22-04-2016 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal TOLA_RS12610 951e78df51c45d3f2403f79d6afedee5 792 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 421 590 1.3E-40 T 22-04-2016 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 TOLA_RS12610 951e78df51c45d3f2403f79d6afedee5 792 PANTHER PTHR31273 5 760 5.5E-149 T 22-04-2016 TOLA_RS12610 951e78df51c45d3f2403f79d6afedee5 792 Gene3D G3DSA:3.40.50.970 91 359 1.2E-5 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS12610 951e78df51c45d3f2403f79d6afedee5 792 SUPERFAMILY SSF52518 85 371 1.18E-20 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 Pfam PF17092 Penicillin-binding protein OB-like domain 317 427 7.4E-31 T 22-04-2016 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00230+2.4.2.-|KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00514+2.4.2.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.-|UniPathway: UPA00219 TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 PANTHER PTHR32282 423 613 1.4E-260 T 22-04-2016 TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 PANTHER PTHR32282 3 311 1.4E-260 T 22-04-2016 TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 PANTHER PTHR32282 653 836 1.4E-260 T 22-04-2016 TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 Pfam PF00905 Penicillin binding protein transpeptidase domain 430 720 3.4E-24 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 SUPERFAMILY SSF56601 212 234 2.36E-118 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 SUPERFAMILY SSF56601 653 813 2.36E-118 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 SUPERFAMILY SSF56601 263 314 2.36E-118 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 SUPERFAMILY SSF56601 424 611 2.36E-118 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 Gene3D G3DSA:3.40.710.10 233 314 4.5E-129 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 Gene3D G3DSA:3.40.710.10 654 813 4.5E-129 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 Gene3D G3DSA:3.40.710.10 424 614 4.5E-129 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 SUPERFAMILY SSF53955 45 258 5.62E-78 T 22-04-2016 IPR023346 Lysozyme-like domain TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 66 762 4.8E-167 T 22-04-2016 TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 Gene3D G3DSA:1.10.3810.10 56 232 5.0E-72 T 22-04-2016 TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 Gene3D G3DSA:2.40.50.140 348 423 2.9E-20 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 PANTHER PTHR32282:SF5 423 613 1.4E-260 T 22-04-2016 TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 PANTHER PTHR32282:SF5 3 311 1.4E-260 T 22-04-2016 TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 PANTHER PTHR32282:SF5 653 836 1.4E-260 T 22-04-2016 TOLA_RS13330 7c6fcde18e837618bd5d3155820fa360 848 Pfam PF00912 Transglycosylase 56 230 9.9E-61 T 22-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 SUPERFAMILY SSF51419 27 266 2.8E-59 T 22-04-2016 IPR029066 PLP-binding barrel TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 276 370 3.0E-22 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 31 264 3.4E-51 T 22-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 254 273 3.0E-20 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 353 366 3.0E-20 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 69 81 3.0E-20 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 171 184 3.0E-20 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 49 67 3.0E-20 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 SUPERFAMILY SSF50621 246 378 4.4E-35 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PRINTS PR01182 Ornithine decarboxylase signature 320 330 2.0E-24 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PRINTS PR01182 Ornithine decarboxylase signature 21 45 2.0E-24 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PRINTS PR01182 Ornithine decarboxylase signature 289 302 2.0E-24 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PRINTS PR01182 Ornithine decarboxylase signature 121 143 2.0E-24 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PRINTS PR01182 Ornithine decarboxylase signature 340 353 2.0E-24 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PRINTS PR01182 Ornithine decarboxylase signature 91 115 2.0E-24 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PRINTS PR01182 Ornithine decarboxylase signature 47 74 2.0E-24 T 22-04-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 Gene3D G3DSA:2.40.37.10 250 379 1.5E-33 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PANTHER PTHR11482:SF6 1 379 4.9E-111 T 22-04-2016 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 PANTHER PTHR11482 1 379 4.9E-111 T 22-04-2016 TOLA_RS04380 5c0a14258d14127732fbf9ce7271a4dd 386 Gene3D G3DSA:3.20.20.10 30 249 1.1E-62 T 22-04-2016 IPR029066 PLP-binding barrel TOLA_RS10995 60e7d453a595759b32aee4b9e59bf34c 550 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 16 163 8.0E-35 T 22-04-2016 IPR006512 YidE/YbjL duplication TOLA_RS10995 60e7d453a595759b32aee4b9e59bf34c 550 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 376 530 1.6E-49 T 22-04-2016 IPR006512 YidE/YbjL duplication TOLA_RS10995 60e7d453a595759b32aee4b9e59bf34c 550 SUPERFAMILY SSF116726 198 268 1.96E-10 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TOLA_RS10995 60e7d453a595759b32aee4b9e59bf34c 550 Gene3D G3DSA:3.30.70.1450 285 357 1.8E-11 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TOLA_RS10995 60e7d453a595759b32aee4b9e59bf34c 550 Gene3D G3DSA:3.30.70.1450 210 269 7.0E-7 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TOLA_RS10995 60e7d453a595759b32aee4b9e59bf34c 550 Pfam PF02080 TrkA-C domain 288 354 8.1E-9 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TOLA_RS10995 60e7d453a595759b32aee4b9e59bf34c 550 Pfam PF02080 TrkA-C domain 208 271 3.1E-9 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TOLA_RS10995 60e7d453a595759b32aee4b9e59bf34c 550 PANTHER PTHR30445 1 547 2.1E-252 T 22-04-2016 TOLA_RS10995 60e7d453a595759b32aee4b9e59bf34c 550 SUPERFAMILY SSF116726 282 357 2.75E-13 T 22-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TOLA_RS10995 60e7d453a595759b32aee4b9e59bf34c 550 PANTHER PTHR30445:SF1 1 547 2.1E-252 T 22-04-2016 TOLA_RS10995 60e7d453a595759b32aee4b9e59bf34c 550 Pfam PF06826 Predicted Permease Membrane Region 371 543 4.4E-46 T 22-04-2016 IPR006512 YidE/YbjL duplication TOLA_RS10995 60e7d453a595759b32aee4b9e59bf34c 550 Pfam PF06826 Predicted Permease Membrane Region 11 176 4.3E-42 T 22-04-2016 IPR006512 YidE/YbjL duplication TOLA_RS05340 81ea425d03f86b8ad7c9454134625b4f 466 Pfam PF13347 MFS/sugar transport protein 13 429 4.0E-93 T 22-04-2016 TOLA_RS05340 81ea425d03f86b8ad7c9454134625b4f 466 PANTHER PTHR11328 8 446 8.7E-102 T 22-04-2016 TOLA_RS05340 81ea425d03f86b8ad7c9454134625b4f 466 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 11 442 1.3E-121 T 22-04-2016 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 TOLA_RS05340 81ea425d03f86b8ad7c9454134625b4f 466 PANTHER PTHR11328:SF24 8 446 8.7E-102 T 22-04-2016 TOLA_RS05340 81ea425d03f86b8ad7c9454134625b4f 466 Gene3D G3DSA:1.20.1250.20 20 207 8.6E-16 T 22-04-2016 TOLA_RS05340 81ea425d03f86b8ad7c9454134625b4f 466 Gene3D G3DSA:1.20.1250.20 230 426 4.8E-5 T 22-04-2016 TOLA_RS05340 81ea425d03f86b8ad7c9454134625b4f 466 SUPERFAMILY SSF103473 8 427 6.63E-30 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS00420 ff2945df574dbbb5651687a5afee172b 146 SUPERFAMILY SSF52402 7 142 2.01E-27 T 22-04-2016 TOLA_RS00420 ff2945df574dbbb5651687a5afee172b 146 PIRSF PIRSF006276 3 145 5.0E-44 T 22-04-2016 IPR006015 Universal stress protein A TOLA_RS00420 ff2945df574dbbb5651687a5afee172b 146 Gene3D G3DSA:3.40.50.620 7 143 2.0E-25 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS00420 ff2945df574dbbb5651687a5afee172b 146 Pfam PF00582 Universal stress protein family 7 142 6.9E-16 T 22-04-2016 IPR006016 UspA GO:0006950 TOLA_RS15170 7042f39efd080aa408722fcdb2799167 98 SUPERFAMILY SSF46785 10 96 1.72E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15170 7042f39efd080aa408722fcdb2799167 98 PANTHER PTHR33154 1 96 2.7E-33 T 22-04-2016 TOLA_RS15170 7042f39efd080aa408722fcdb2799167 98 PANTHER PTHR33154:SF10 1 96 2.7E-33 T 22-04-2016 TOLA_RS15170 7042f39efd080aa408722fcdb2799167 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 17 32 1.8E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TOLA_RS15170 7042f39efd080aa408722fcdb2799167 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 1.8E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TOLA_RS15170 7042f39efd080aa408722fcdb2799167 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 1.8E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TOLA_RS15170 7042f39efd080aa408722fcdb2799167 98 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 47 1.8E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TOLA_RS15170 7042f39efd080aa408722fcdb2799167 98 Pfam PF01022 Bacterial regulatory protein, arsR family 25 67 3.1E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TOLA_RS15170 7042f39efd080aa408722fcdb2799167 98 SMART SM00418 15 93 2.9E-23 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TOLA_RS15170 7042f39efd080aa408722fcdb2799167 98 Gene3D G3DSA:1.10.10.10 2 97 6.2E-37 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 PANTHER PTHR22942 5 335 2.4E-206 T 22-04-2016 TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 Hamap MF_00268 Protein RecA [recA]. 5 329 50.972 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 SUPERFAMILY SSF54752 268 324 1.57E-19 T 22-04-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 SMART SM00382 57 228 5.0E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 SUPERFAMILY SSF52540 4 267 1.27E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 PRINTS PR00142 RecA protein signature 297 314 4.9E-83 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 PRINTS PR00142 RecA protein signature 210 238 4.9E-83 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 PRINTS PR00142 RecA protein signature 243 272 4.9E-83 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 PRINTS PR00142 RecA protein signature 127 156 4.9E-83 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 PRINTS PR00142 RecA protein signature 93 122 4.9E-83 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 PRINTS PR00142 RecA protein signature 165 194 4.9E-83 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 ProSitePatterns PS00321 recA signature. 213 221 - T 22-04-2016 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 PANTHER PTHR22942:SF1 5 335 2.4E-206 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 Pfam PF00154 recA bacterial DNA recombination protein 7 268 1.2E-145 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 Gene3D G3DSA:3.40.50.300 28 267 3.5E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 Gene3D G3DSA:3.30.250.10 268 326 4.3E-26 T 22-04-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal TOLA_RS13960 06dd1b468c6378afdcd4ffe7269e5ba4 360 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 324 6.7E-172 T 22-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TOLA_RS14050 cf4601786b1b90009eeab2da4d6a31f8 203 Pfam PF01810 LysE type translocator 16 191 4.2E-16 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS14050 cf4601786b1b90009eeab2da4d6a31f8 203 PANTHER PTHR30086:SF12 1 190 9.4E-58 T 22-04-2016 TOLA_RS14050 cf4601786b1b90009eeab2da4d6a31f8 203 PANTHER PTHR30086 1 190 9.4E-58 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS12790 065fc425d68c4f4ca4a877f84dd8ba20 518 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 430 6.8E-86 T 22-04-2016 IPR000914 Solute-binding protein family 5 domain TOLA_RS12790 065fc425d68c4f4ca4a877f84dd8ba20 518 PIRSF PIRSF002741 23 502 7.6E-87 T 22-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TOLA_RS12790 065fc425d68c4f4ca4a877f84dd8ba20 518 SUPERFAMILY SSF53850 27 514 1.12E-121 T 22-04-2016 TOLA_RS12790 065fc425d68c4f4ca4a877f84dd8ba20 518 PANTHER PTHR30290 28 510 5.6E-150 T 22-04-2016 TOLA_RS12790 065fc425d68c4f4ca4a877f84dd8ba20 518 Gene3D G3DSA:3.40.190.10 125 286 7.1E-40 T 22-04-2016 TOLA_RS12790 065fc425d68c4f4ca4a877f84dd8ba20 518 Gene3D G3DSA:3.10.105.10 287 486 1.5E-50 T 22-04-2016 TOLA_RS12790 065fc425d68c4f4ca4a877f84dd8ba20 518 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 72 93 - T 22-04-2016 IPR023765 Solute-binding protein family 5, conserved site TOLA_RS12790 065fc425d68c4f4ca4a877f84dd8ba20 518 PANTHER PTHR30290:SF24 28 510 5.6E-150 T 22-04-2016 TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 SUPERFAMILY SSF46785 7 65 3.19E-13 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 SMART SM01134 73 234 7.0E-64 T 22-04-2016 TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 SUPERFAMILY SSF100950 77 233 1.31E-34 T 22-04-2016 TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 Pfam PF08220 DeoR-like helix-turn-helix domain 9 60 1.7E-17 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 Gene3D G3DSA:1.10.10.10 3 54 1.0E-9 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 PANTHER PTHR30363:SF15 3 255 1.9E-142 T 22-04-2016 TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 41 59 1.2E-6 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 27 41 1.2E-6 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 Pfam PF00455 DeoR C terminal sensor domain 77 232 9.7E-46 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 Gene3D G3DSA:3.40.50.1360 75 222 3.5E-19 T 22-04-2016 TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 SMART SM00420 9 61 2.8E-16 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 PANTHER PTHR30363 3 255 1.9E-142 T 22-04-2016 TOLA_RS01585 3ddc46e089a37b8a92dc992a32369cfb 257 ProSitePatterns PS00894 DeoR-type HTH domain signature. 9 43 - T 22-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 TOLA_RS12820 1008c427e3e9067dc746282d623f3c72 128 PANTHER PTHR30093 1 66 1.5E-20 T 22-04-2016 TOLA_RS12820 1008c427e3e9067dc746282d623f3c72 128 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 28 3.4E-10 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS12820 1008c427e3e9067dc746282d623f3c72 128 PANTHER PTHR30093:SF4 1 66 1.5E-20 T 22-04-2016 TOLA_RS12820 1008c427e3e9067dc746282d623f3c72 128 Gene3D G3DSA:3.30.700.10 8 115 2.5E-19 T 22-04-2016 TOLA_RS12820 1008c427e3e9067dc746282d623f3c72 128 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS12820 1008c427e3e9067dc746282d623f3c72 128 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 29 113 3.5E-20 T 22-04-2016 IPR031982 Type IV minor pilin ComP TOLA_RS12820 1008c427e3e9067dc746282d623f3c72 128 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 2 27 2.4E-9 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS12820 1008c427e3e9067dc746282d623f3c72 128 SUPERFAMILY SSF54523 8 126 5.76E-23 T 22-04-2016 TOLA_RS09300 471950e30451bb87acf92f016cd15c9f 317 SUPERFAMILY SSF52922 175 309 1.15E-30 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS09300 471950e30451bb87acf92f016cd15c9f 317 Pfam PF02780 Transketolase, C-terminal domain 181 303 5.4E-27 T 22-04-2016 IPR033248 Transketolase, C-terminal domain TOLA_RS09300 471950e30451bb87acf92f016cd15c9f 317 SUPERFAMILY SSF52518 6 179 3.68E-35 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS09300 471950e30451bb87acf92f016cd15c9f 317 Pfam PF02779 Transketolase, pyrimidine binding domain 14 168 1.0E-17 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS09300 471950e30451bb87acf92f016cd15c9f 317 PANTHER PTHR11624:SF2 10 312 3.2E-74 T 22-04-2016 TOLA_RS09300 471950e30451bb87acf92f016cd15c9f 317 Gene3D G3DSA:3.40.50.970 12 181 1.4E-38 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS09300 471950e30451bb87acf92f016cd15c9f 317 Gene3D G3DSA:3.40.50.920 182 310 3.2E-32 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS09300 471950e30451bb87acf92f016cd15c9f 317 SMART SM00861 1 170 1.3E-28 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS09300 471950e30451bb87acf92f016cd15c9f 317 PANTHER PTHR11624 10 312 3.2E-74 T 22-04-2016 IPR033247 Transketolase family TOLA_RS11395 cc710fd3b59a50195d89b86139194897 134 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 118 22.136 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 TOLA_RS11395 cc710fd3b59a50195d89b86139194897 134 ProSitePatterns PS01319 Ribosome-binding factor A signature. 77 98 - T 22-04-2016 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 TOLA_RS11395 cc710fd3b59a50195d89b86139194897 134 SUPERFAMILY SSF89919 2 105 3.79E-32 T 22-04-2016 IPR023799 Ribosome-binding factor A domain TOLA_RS11395 cc710fd3b59a50195d89b86139194897 134 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 98 1.0E-30 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 TOLA_RS11395 cc710fd3b59a50195d89b86139194897 134 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 115 3.7E-40 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 TOLA_RS11395 cc710fd3b59a50195d89b86139194897 134 Pfam PF02033 Ribosome-binding factor A 7 110 8.0E-31 T 22-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 TOLA_RS11395 cc710fd3b59a50195d89b86139194897 134 PANTHER PTHR33515 1 134 7.1E-44 T 22-04-2016 TOLA_RS11395 cc710fd3b59a50195d89b86139194897 134 Gene3D G3DSA:3.30.300.20 5 118 3.6E-39 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta TOLA_RS01115 aaabb27d70468636f80ea7ad18b50d00 300 Gene3D G3DSA:3.30.200.20 25 143 7.5E-20 T 22-04-2016 TOLA_RS01115 aaabb27d70468636f80ea7ad18b50d00 300 Gene3D G3DSA:1.10.510.10 144 247 1.8E-30 T 22-04-2016 TOLA_RS01115 aaabb27d70468636f80ea7ad18b50d00 300 Pfam PF00069 Protein kinase domain 29 250 4.5E-39 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOLA_RS01115 aaabb27d70468636f80ea7ad18b50d00 300 PANTHER PTHR24362 24 247 2.2E-41 T 22-04-2016 TOLA_RS01115 aaabb27d70468636f80ea7ad18b50d00 300 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 155 167 - T 22-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TOLA_RS01115 aaabb27d70468636f80ea7ad18b50d00 300 SUPERFAMILY SSF56112 24 251 6.34E-53 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS01115 aaabb27d70468636f80ea7ad18b50d00 300 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 35 64 - T 22-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 TOLA_RS01115 aaabb27d70468636f80ea7ad18b50d00 300 SMART SM00220 29 286 1.7E-27 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOLA_RS02675 b56c03af50134589bd1b5dbe4879e6eb 152 SUPERFAMILY SSF89447 1 138 1.88E-44 T 22-04-2016 TOLA_RS02675 b56c03af50134589bd1b5dbe4879e6eb 152 Pfam PF02381 MraZ protein, putative antitoxin-like 78 134 1.3E-18 T 22-04-2016 IPR020603 MraZ domain TOLA_RS02675 b56c03af50134589bd1b5dbe4879e6eb 152 Pfam PF02381 MraZ protein, putative antitoxin-like 1 75 3.0E-19 T 22-04-2016 IPR020603 MraZ domain TOLA_RS02675 b56c03af50134589bd1b5dbe4879e6eb 152 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 135 4.0E-51 T 22-04-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TOLA_RS02675 b56c03af50134589bd1b5dbe4879e6eb 152 PANTHER PTHR34701 2 151 4.8E-61 T 22-04-2016 TOLA_RS02675 b56c03af50134589bd1b5dbe4879e6eb 152 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 152 1.6E-55 T 22-04-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TOLA_RS02675 b56c03af50134589bd1b5dbe4879e6eb 152 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 152 56.573 T 22-04-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 PANTHER PTHR30075 1 300 4.0E-270 T 22-04-2016 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 113 137 2.2E-70 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 82 102 2.2E-70 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 162 177 2.2E-70 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 61 76 2.2E-70 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 139 159 2.2E-70 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 253 269 2.2E-70 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 7 293 61.344 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 SUPERFAMILY SSF55681 8 292 2.71E-133 T 22-04-2016 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 9 291 5.5E-148 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 7 300 1.3E-169 T 22-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 Gene3D G3DSA:1.20.58.180 215 298 3.2E-36 T 22-04-2016 TOLA_RS00045 a84f5cd72300a2fb83561a55087b4254 304 Gene3D G3DSA:3.30.930.10 5 214 2.2E-104 T 22-04-2016 TOLA_RS08410 55581ec6ab689172b8ca02e7e4a5b302 325 SUPERFAMILY SSF55347 128 290 5.23E-21 T 22-04-2016 TOLA_RS08410 55581ec6ab689172b8ca02e7e4a5b302 325 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 116 2.6E-19 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 TOLA_RS08410 55581ec6ab689172b8ca02e7e4a5b302 325 PANTHER PTHR22604 1 317 1.1E-58 T 22-04-2016 TOLA_RS08410 55581ec6ab689172b8ca02e7e4a5b302 325 Gene3D G3DSA:3.30.360.10 143 324 3.9E-56 T 22-04-2016 TOLA_RS08410 55581ec6ab689172b8ca02e7e4a5b302 325 PANTHER PTHR22604:SF76 1 317 1.1E-58 T 22-04-2016 TOLA_RS08410 55581ec6ab689172b8ca02e7e4a5b302 325 SUPERFAMILY SSF51735 2 152 9.77E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS08410 55581ec6ab689172b8ca02e7e4a5b302 325 Gene3D G3DSA:3.40.50.720 1 142 2.0E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 SUPERFAMILY SSF52540 6 219 2.06E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 PANTHER PTHR23115 1 393 0.0 T 22-04-2016 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 2.8E-17 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 145 3.7E-14 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.5E-24 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.5E-24 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.5E-24 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.5E-24 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.5E-24 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 Gene3D G3DSA:2.40.30.10 209 298 4.7E-37 T 22-04-2016 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 3.5E-58 T 22-04-2016 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 61.748 T 22-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 Gene3D G3DSA:2.40.30.10 301 393 6.7E-47 T 22-04-2016 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 SUPERFAMILY SSF50465 298 393 2.04E-36 T 22-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 Gene3D G3DSA:3.40.50.300 3 208 3.1E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 1.7E-33 T 22-04-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 394 1.4E-238 T 22-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 PANTHER PTHR23115:SF151 1 393 0.0 T 22-04-2016 TOLA_RS14290 4181a405854a37279c893215fcba87cd 394 SUPERFAMILY SSF50447 205 301 1.12E-30 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain TOLA_RS00815 04e153b0d606c85bae9703803c3aea57 167 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 6 159 29.805 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 TOLA_RS00815 04e153b0d606c85bae9703803c3aea57 167 PIRSF PIRSF001338 1 166 5.4E-61 T 22-04-2016 IPR024694 N5-carboxyaminoimidazole ribonucleotide mutase PurE GO:0006189|GO:0034023 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234|UniPathway: UPA00074 TOLA_RS00815 04e153b0d606c85bae9703803c3aea57 167 Pfam PF00731 AIR carboxylase 6 153 2.5E-57 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 TOLA_RS00815 04e153b0d606c85bae9703803c3aea57 167 Gene3D G3DSA:3.40.50.7700 2 163 4.6E-65 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 TOLA_RS00815 04e153b0d606c85bae9703803c3aea57 167 PANTHER PTHR23046 3 167 8.8E-69 T 22-04-2016 TOLA_RS00815 04e153b0d606c85bae9703803c3aea57 167 SUPERFAMILY SSF52255 5 163 4.71E-59 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 TOLA_RS00815 04e153b0d606c85bae9703803c3aea57 167 PANTHER PTHR23046:SF2 3 167 8.8E-69 T 22-04-2016 TOLA_RS00815 04e153b0d606c85bae9703803c3aea57 167 SMART SM01001 4 155 1.8E-87 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 TOLA_RS00815 04e153b0d606c85bae9703803c3aea57 167 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 6 162 2.0E-57 T 22-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 TOLA_RS01665 4c6e2138cb8e4d3feb5de3178a1cf9b8 141 PANTHER PTHR12418 33 137 6.1E-12 T 22-04-2016 TOLA_RS01665 4c6e2138cb8e4d3feb5de3178a1cf9b8 141 PANTHER PTHR12418:SF16 33 137 6.1E-12 T 22-04-2016 TOLA_RS01665 4c6e2138cb8e4d3feb5de3178a1cf9b8 141 SUPERFAMILY SSF54637 8 135 1.42E-28 T 22-04-2016 IPR029069 HotDog domain TOLA_RS01665 4c6e2138cb8e4d3feb5de3178a1cf9b8 141 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 27 110 6.0E-12 T 22-04-2016 IPR003736 Phenylacetic acid degradation-related domain TOLA_RS01665 4c6e2138cb8e4d3feb5de3178a1cf9b8 141 Pfam PF03061 Thioesterase superfamily 56 110 5.3E-9 T 22-04-2016 IPR006683 Thioesterase domain TOLA_RS01665 4c6e2138cb8e4d3feb5de3178a1cf9b8 141 Gene3D G3DSA:3.10.129.10 9 137 2.7E-33 T 22-04-2016 IPR029069 HotDog domain TOLA_RS09425 df75c084948a8203165bad58eeaaec85 411 PANTHER PTHR11706:SF2 375 406 1.4E-96 T 22-04-2016 TOLA_RS09425 df75c084948a8203165bad58eeaaec85 411 PANTHER PTHR11706:SF2 2 225 1.4E-96 T 22-04-2016 TOLA_RS09425 df75c084948a8203165bad58eeaaec85 411 Pfam PF01566 Natural resistance-associated macrophage protein 51 378 3.3E-18 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 TOLA_RS09425 df75c084948a8203165bad58eeaaec85 411 PANTHER PTHR11706 375 406 1.4E-96 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 TOLA_RS09425 df75c084948a8203165bad58eeaaec85 411 PANTHER PTHR11706 2 225 1.4E-96 T 22-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 TOLA_RS13140 fa08edbef938617cddf9255a483af519 443 SUPERFAMILY SSF103473 10 438 1.15E-79 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS13140 fa08edbef938617cddf9255a483af519 443 Gene3D G3DSA:1.20.1250.20 11 208 2.7E-45 T 22-04-2016 TOLA_RS13140 fa08edbef938617cddf9255a483af519 443 Pfam PF07690 Major Facilitator Superfamily 22 316 6.0E-49 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS13140 fa08edbef938617cddf9255a483af519 443 PIRSF PIRSF002808 3 442 5.0E-45 T 22-04-2016 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 TOLA_RS13140 fa08edbef938617cddf9255a483af519 443 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 24 433 4.0E-153 T 22-04-2016 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 TOLA_RS13140 fa08edbef938617cddf9255a483af519 443 PANTHER PTHR11662 10 442 9.3E-225 T 22-04-2016 TOLA_RS13140 fa08edbef938617cddf9255a483af519 443 Gene3D G3DSA:1.20.1250.20 242 435 8.1E-33 T 22-04-2016 TOLA_RS13140 fa08edbef938617cddf9255a483af519 443 PANTHER PTHR11662:SF18 10 442 9.3E-225 T 22-04-2016 TOLA_RS10100 7212a094091691c293996ef48c2187e3 489 Gene3D G3DSA:2.60.40.420 192 305 2.2E-27 T 22-04-2016 IPR008972 Cupredoxin TOLA_RS10100 7212a094091691c293996ef48c2187e3 489 Pfam PF07731 Multicopper oxidase 376 485 2.3E-28 T 22-04-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 TOLA_RS10100 7212a094091691c293996ef48c2187e3 489 PANTHER PTHR11709 85 488 8.4E-92 T 22-04-2016 TOLA_RS10100 7212a094091691c293996ef48c2187e3 489 SUPERFAMILY SSF49503 374 486 3.21E-31 T 22-04-2016 IPR008972 Cupredoxin TOLA_RS10100 7212a094091691c293996ef48c2187e3 489 SUPERFAMILY SSF49503 196 304 7.14E-19 T 22-04-2016 IPR008972 Cupredoxin TOLA_RS10100 7212a094091691c293996ef48c2187e3 489 Pfam PF07732 Multicopper oxidase 77 190 5.1E-32 T 22-04-2016 IPR011707 Multicopper oxidase, type 3 GO:0005507 TOLA_RS10100 7212a094091691c293996ef48c2187e3 489 ProSitePatterns PS00080 Multicopper oxidases signature 2. 471 482 - T 22-04-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 TOLA_RS10100 7212a094091691c293996ef48c2187e3 489 Gene3D G3DSA:2.60.40.420 343 485 1.2E-35 T 22-04-2016 IPR008972 Cupredoxin TOLA_RS10100 7212a094091691c293996ef48c2187e3 489 PANTHER PTHR11709:SF2 85 488 8.4E-92 T 22-04-2016 TOLA_RS10100 7212a094091691c293996ef48c2187e3 489 SUPERFAMILY SSF49503 60 191 4.03E-37 T 22-04-2016 IPR008972 Cupredoxin TOLA_RS10100 7212a094091691c293996ef48c2187e3 489 Gene3D G3DSA:2.60.40.420 62 191 2.0E-36 T 22-04-2016 IPR008972 Cupredoxin TOLA_RS10100 7212a094091691c293996ef48c2187e3 489 Pfam PF00394 Multicopper oxidase 220 320 1.1E-8 T 22-04-2016 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 TOLA_RS05390 a0735729e1913a654475d5d2d3d80fef 422 Pfam PF04285 Protein of unknown function (DUF444) 3 420 5.4E-184 T 22-04-2016 IPR006698 Uncharacterised protein family UPF0229 TOLA_RS05390 a0735729e1913a654475d5d2d3d80fef 422 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 422 39.411 T 22-04-2016 IPR006698 Uncharacterised protein family UPF0229 TOLA_RS05390 a0735729e1913a654475d5d2d3d80fef 422 SUPERFAMILY SSF53300 251 409 9.34E-5 T 22-04-2016 IPR002035 von Willebrand factor, type A TOLA_RS05390 a0735729e1913a654475d5d2d3d80fef 422 PANTHER PTHR30510 1 420 4.8E-175 T 22-04-2016 TOLA_RS00290 29966d696af8198dbb74593404bda2fa 313 SUPERFAMILY SSF53822 10 307 3.37E-78 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS00290 29966d696af8198dbb74593404bda2fa 313 Gene3D G3DSA:3.40.50.2300 22 145 2.2E-36 T 22-04-2016 TOLA_RS00290 29966d696af8198dbb74593404bda2fa 313 Pfam PF13407 Periplasmic binding protein domain 30 285 2.8E-53 T 22-04-2016 IPR025997 Periplasmic binding protein TOLA_RS00290 29966d696af8198dbb74593404bda2fa 313 PANTHER PTHR32196 1 304 2.5E-136 T 22-04-2016 TOLA_RS00290 29966d696af8198dbb74593404bda2fa 313 Gene3D G3DSA:3.40.50.2300 146 307 1.3E-45 T 22-04-2016 TOLA_RS00290 29966d696af8198dbb74593404bda2fa 313 PANTHER PTHR32196:SF41 1 304 2.5E-136 T 22-04-2016 TOLA_RS07115 7375661b4bfd0bd4031524774aa00d95 452 Pfam PF01554 MatE 17 176 9.3E-36 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 TOLA_RS07115 7375661b4bfd0bd4031524774aa00d95 452 Pfam PF01554 MatE 243 402 1.2E-32 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 TOLA_RS07115 7375661b4bfd0bd4031524774aa00d95 452 PANTHER PTHR11206 3 444 2.8E-189 T 22-04-2016 TOLA_RS07115 7375661b4bfd0bd4031524774aa00d95 452 PANTHER PTHR11206:SF153 3 444 2.8E-189 T 22-04-2016 TOLA_RS07115 7375661b4bfd0bd4031524774aa00d95 452 PIRSF PIRSF006603 4 451 2.7E-62 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 TOLA_RS07115 7375661b4bfd0bd4031524774aa00d95 452 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 421 4.2E-108 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 TOLA_RS15095 4f9597de3b07b0eb3b6bcb64e33c5144 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.1E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS15095 4f9597de3b07b0eb3b6bcb64e33c5144 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.1E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS15095 4f9597de3b07b0eb3b6bcb64e33c5144 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.1E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS15095 4f9597de3b07b0eb3b6bcb64e33c5144 295 Gene3D G3DSA:3.40.190.10 92 178 9.7E-14 T 22-04-2016 TOLA_RS15095 4f9597de3b07b0eb3b6bcb64e33c5144 295 SUPERFAMILY SSF46785 1 110 8.17E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15095 4f9597de3b07b0eb3b6bcb64e33c5144 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.0E-17 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS15095 4f9597de3b07b0eb3b6bcb64e33c5144 295 PANTHER PTHR30126:SF25 1 293 4.7E-126 T 22-04-2016 TOLA_RS15095 4f9597de3b07b0eb3b6bcb64e33c5144 295 Gene3D G3DSA:3.40.190.10 179 264 1.6E-15 T 22-04-2016 TOLA_RS15095 4f9597de3b07b0eb3b6bcb64e33c5144 295 SUPERFAMILY SSF53850 91 292 2.33E-37 T 22-04-2016 TOLA_RS15095 4f9597de3b07b0eb3b6bcb64e33c5144 295 PANTHER PTHR30126 1 293 4.7E-126 T 22-04-2016 TOLA_RS15095 4f9597de3b07b0eb3b6bcb64e33c5144 295 Pfam PF03466 LysR substrate binding domain 91 290 1.7E-37 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS15095 4f9597de3b07b0eb3b6bcb64e33c5144 295 Gene3D G3DSA:1.10.10.10 1 85 1.2E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14010 0896ed96b5c098b21dcad66b67f17a31 105 PANTHER PTHR37485 2 105 4.2E-37 T 22-04-2016 TOLA_RS14010 0896ed96b5c098b21dcad66b67f17a31 105 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 34.585 T 22-04-2016 IPR023081 Cell division protein FtsB TOLA_RS14010 0896ed96b5c098b21dcad66b67f17a31 105 Pfam PF04977 Septum formation initiator 12 88 1.3E-23 T 22-04-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 TOLA_RS14010 0896ed96b5c098b21dcad66b67f17a31 105 PANTHER PTHR37485:SF1 2 105 4.2E-37 T 22-04-2016 TOLA_RS14310 414b701cb3dc1f988063a71de5a5153b 321 Pfam PF02237 Biotin protein ligase C terminal domain 275 318 3.2E-9 T 22-04-2016 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15 TOLA_RS14310 414b701cb3dc1f988063a71de5a5153b 321 Gene3D G3DSA:2.30.30.100 272 319 1.5E-17 T 22-04-2016 TOLA_RS14310 414b701cb3dc1f988063a71de5a5153b 321 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 8 318 30.687 T 22-04-2016 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 TOLA_RS14310 414b701cb3dc1f988063a71de5a5153b 321 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 82 318 1.5E-62 T 22-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 TOLA_RS14310 414b701cb3dc1f988063a71de5a5153b 321 Gene3D G3DSA:3.30.930.10 72 269 3.8E-57 T 22-04-2016 TOLA_RS14310 414b701cb3dc1f988063a71de5a5153b 321 SUPERFAMILY SSF46785 4 61 3.43E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14310 414b701cb3dc1f988063a71de5a5153b 321 SUPERFAMILY SSF50037 272 318 6.41E-10 T 22-04-2016 IPR008988 Transcriptional repressor, C-terminal TOLA_RS14310 414b701cb3dc1f988063a71de5a5153b 321 Pfam PF08279 HTH domain 7 60 8.3E-11 T 22-04-2016 IPR013196 Helix-turn-helix, type 11 TOLA_RS14310 414b701cb3dc1f988063a71de5a5153b 321 Pfam PF03099 Biotin/lipoate A/B protein ligase family 87 209 2.1E-18 T 22-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 TOLA_RS14310 414b701cb3dc1f988063a71de5a5153b 321 Gene3D G3DSA:1.10.10.10 5 64 3.8E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14310 414b701cb3dc1f988063a71de5a5153b 321 PANTHER PTHR12835 3 318 5.5E-69 T 22-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 TOLA_RS14310 414b701cb3dc1f988063a71de5a5153b 321 SUPERFAMILY SSF55681 71 270 8.7E-57 T 22-04-2016 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 Gene3D G3DSA:3.90.480.10 65 137 1.6E-62 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 Gene3D G3DSA:3.90.480.10 332 413 1.6E-62 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 10 549 2.1E-281 T 22-04-2016 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 468 484 - T 22-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 PANTHER PTHR11493 3 550 3.3E-262 T 22-04-2016 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 PANTHER PTHR11493:SF47 3 550 3.3E-262 T 22-04-2016 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 Gene3D G3DSA:3.30.413.10 140 329 3.3E-70 T 22-04-2016 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 SUPERFAMILY SSF56014 419 552 1.44E-35 T 22-04-2016 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 164 321 5.8E-47 T 22-04-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 421 548 3.3E-5 T 22-04-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 SUPERFAMILY SSF55124 336 412 2.94E-22 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 1 561 58.654 T 22-04-2016 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 SUPERFAMILY SSF56014 140 334 1.96E-57 T 22-04-2016 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 Gene3D G3DSA:3.30.413.10 419 548 6.6E-34 T 22-04-2016 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 SUPERFAMILY SSF55124 5 136 1.06E-24 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 PRINTS PR00397 Sirohaem Fe-binding site signature 420 438 4.3E-9 T 22-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 PRINTS PR00397 Sirohaem Fe-binding site signature 468 486 4.3E-9 T 22-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 69 131 1.2E-13 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11960 72a25f4b1d58bcab541eeb8f85b7508d 562 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 343 407 8.0E-15 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS00340 f2993d1b98d1873a2d9c2e7a64bf118c 384 SUPERFAMILY SSF53383 2 378 1.41E-95 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS00340 f2993d1b98d1873a2d9c2e7a64bf118c 384 PANTHER PTHR11751:SF294 9 380 1.9E-113 T 22-04-2016 TOLA_RS00340 f2993d1b98d1873a2d9c2e7a64bf118c 384 PANTHER PTHR11751 9 380 1.9E-113 T 22-04-2016 TOLA_RS00340 f2993d1b98d1873a2d9c2e7a64bf118c 384 Pfam PF00155 Aminotransferase class I and II 49 369 4.1E-35 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TOLA_RS00340 f2993d1b98d1873a2d9c2e7a64bf118c 384 Gene3D G3DSA:3.90.1150.10 260 378 1.3E-10 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS00340 f2993d1b98d1873a2d9c2e7a64bf118c 384 Gene3D G3DSA:3.40.640.10 49 259 4.8E-70 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS07785 ea7bb1b3668ff44a99d55ccaac41c8d7 214 Hamap MF_00551 Uridine kinase [udk]. 5 213 39.617 T 22-04-2016 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 TOLA_RS07785 ea7bb1b3668ff44a99d55ccaac41c8d7 214 TIGRFAM TIGR00235 udk: uridine kinase 5 212 1.5E-89 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 TOLA_RS07785 ea7bb1b3668ff44a99d55ccaac41c8d7 214 Gene3D G3DSA:3.40.50.300 6 205 4.2E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07785 ea7bb1b3668ff44a99d55ccaac41c8d7 214 PANTHER PTHR10285 9 209 1.9E-89 T 22-04-2016 TOLA_RS07785 ea7bb1b3668ff44a99d55ccaac41c8d7 214 PRINTS PR00988 Uridine kinase signature 179 192 1.2E-38 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 TOLA_RS07785 ea7bb1b3668ff44a99d55ccaac41c8d7 214 PRINTS PR00988 Uridine kinase signature 143 153 1.2E-38 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 TOLA_RS07785 ea7bb1b3668ff44a99d55ccaac41c8d7 214 PRINTS PR00988 Uridine kinase signature 87 102 1.2E-38 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 TOLA_RS07785 ea7bb1b3668ff44a99d55ccaac41c8d7 214 PRINTS PR00988 Uridine kinase signature 8 25 1.2E-38 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 TOLA_RS07785 ea7bb1b3668ff44a99d55ccaac41c8d7 214 PRINTS PR00988 Uridine kinase signature 42 53 1.2E-38 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 TOLA_RS07785 ea7bb1b3668ff44a99d55ccaac41c8d7 214 PRINTS PR00988 Uridine kinase signature 157 168 1.2E-38 T 22-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 TOLA_RS07785 ea7bb1b3668ff44a99d55ccaac41c8d7 214 SUPERFAMILY SSF52540 9 205 5.86E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07785 ea7bb1b3668ff44a99d55ccaac41c8d7 214 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 10 199 3.4E-42 T 22-04-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 Gene3D G3DSA:3.40.120.10 227 318 2.2E-44 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 141 150 - T 22-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 TIGRFAM TIGR01132 pgm: phosphoglucomutase, alpha-D-glucose phosphate-specific 1 544 2.3E-282 T 22-04-2016 IPR005852 Phosphoglucomutase, alpha-D-glucose specific GO:0004614|GO:0005975 KEGG: 00010+5.4.2.2|KEGG: 00030+5.4.2.2|KEGG: 00052+5.4.2.2|KEGG: 00230+5.4.2.2|KEGG: 00500+5.4.2.2|KEGG: 00520+5.4.2.2|KEGG: 00521+5.4.2.2|MetaCyc: PWY-2723|MetaCyc: PWY-3801|MetaCyc: PWY-5384|MetaCyc: PWY-5661|MetaCyc: PWY-5940|MetaCyc: PWY-5941|MetaCyc: PWY-622|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|MetaCyc: PWY-7343 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 Gene3D G3DSA:3.40.120.10 31 226 5.3E-60 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 PANTHER PTHR22573:SF52 18 544 2.7E-268 T 22-04-2016 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 321 440 6.3E-29 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 SUPERFAMILY SSF53738 306 448 6.28E-33 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 40 183 7.8E-38 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 SUPERFAMILY SSF53738 210 318 1.65E-9 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 491 536 8.0E-8 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 Gene3D G3DSA:3.30.310.50 467 544 8.4E-27 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 SUPERFAMILY SSF55957 434 544 1.14E-20 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 211 318 3.1E-16 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 SUPERFAMILY SSF53738 26 236 2.28E-50 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 PANTHER PTHR22573 18 544 2.7E-268 T 22-04-2016 TOLA_RS04425 90d7c6245bfd3f365bd8985c3b451c23 549 Gene3D G3DSA:3.40.120.10 319 442 3.6E-34 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS04185 1cb0aa8537b0502a90992ee3dc55f181 257 PIRSF PIRSF006648 8 253 2.2E-21 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 TOLA_RS04185 1cb0aa8537b0502a90992ee3dc55f181 257 PANTHER PTHR30413:SF2 1 256 7.3E-158 T 22-04-2016 TOLA_RS04185 1cb0aa8537b0502a90992ee3dc55f181 257 Pfam PF01061 ABC-2 type transporter 10 219 4.7E-38 T 22-04-2016 IPR013525 ABC-2 type transporter GO:0016020 TOLA_RS04185 1cb0aa8537b0502a90992ee3dc55f181 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 197 216 1.3E-5 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 TOLA_RS04185 1cb0aa8537b0502a90992ee3dc55f181 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 177 196 1.3E-5 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 TOLA_RS04185 1cb0aa8537b0502a90992ee3dc55f181 257 PRINTS PR00164 ABC-2 type transport system membrane protein signature 59 81 1.3E-5 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 TOLA_RS04185 1cb0aa8537b0502a90992ee3dc55f181 257 PANTHER PTHR30413 1 256 7.3E-158 T 22-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 SUPERFAMILY SSF46548 222 350 8.72E-13 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 Pfam PF10531 SLBB domain 183 227 6.0E-11 T 22-04-2016 IPR019554 Soluble ligand binding domain TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 29 168 1.1E-39 T 22-04-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 Pfam PF13375 RnfC Barrel sandwich hybrid domain 394 455 9.6E-17 T 22-04-2016 IPR026902 RnfC Barrel sandwich hybrid domain TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 PANTHER PTHR11780:SF9 27 388 5.9E-182 T 22-04-2016 TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 SUPERFAMILY SSF142984 180 249 2.09E-14 T 22-04-2016 TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 Gene3D G3DSA:1.10.1060.10 227 350 5.3E-11 T 22-04-2016 TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 Gene3D G3DSA:2.40.50.100 407 449 2.8E-4 T 22-04-2016 TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 272 283 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 SUPERFAMILY SSF142019 11 186 2.75E-45 T 22-04-2016 TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 PIRSF PIRSF036408 20 458 6.5E-180 T 22-04-2016 IPR017054 Propanediol utilization protein, PduS, predicted TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 PANTHER PTHR11780 27 388 5.9E-182 T 22-04-2016 TOLA_RS08640 b3cac006896c14ca9b895e320796f776 459 Pfam PF13534 4Fe-4S dicluster domain 272 332 1.4E-7 T 22-04-2016 TOLA_RS04445 901dd5b8096217644870d821e1512498 320 Gene3D G3DSA:1.10.3720.10 179 303 3.3E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04445 901dd5b8096217644870d821e1512498 320 Gene3D G3DSA:1.10.3720.10 65 139 3.3E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04445 901dd5b8096217644870d821e1512498 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 312 2.2E-39 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04445 901dd5b8096217644870d821e1512498 320 PANTHER PTHR30465 1 149 2.2E-93 T 22-04-2016 TOLA_RS04445 901dd5b8096217644870d821e1512498 320 PANTHER PTHR30465 170 313 2.2E-93 T 22-04-2016 TOLA_RS04445 901dd5b8096217644870d821e1512498 320 PANTHER PTHR30465:SF65 1 149 2.2E-93 T 22-04-2016 TOLA_RS04445 901dd5b8096217644870d821e1512498 320 PANTHER PTHR30465:SF65 170 313 2.2E-93 T 22-04-2016 TOLA_RS04445 901dd5b8096217644870d821e1512498 320 SUPERFAMILY SSF161098 68 136 1.96E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04445 901dd5b8096217644870d821e1512498 320 SUPERFAMILY SSF161098 176 297 1.96E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS01470 5b81dfe94dd4d5b53a47a58f2b8ab8eb 494 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 35 204 3.5E-58 T 22-04-2016 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS01470 5b81dfe94dd4d5b53a47a58f2b8ab8eb 494 SUPERFAMILY SSF48179 210 343 4.08E-38 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS01470 5b81dfe94dd4d5b53a47a58f2b8ab8eb 494 PANTHER PTHR21371 1 492 2.8E-202 T 22-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS01470 5b81dfe94dd4d5b53a47a58f2b8ab8eb 494 Gene3D G3DSA:1.10.1040.10 363 484 1.3E-16 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TOLA_RS01470 5b81dfe94dd4d5b53a47a58f2b8ab8eb 494 SUPERFAMILY SSF51735 28 209 4.34E-58 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01470 5b81dfe94dd4d5b53a47a58f2b8ab8eb 494 SUPERFAMILY SSF48179 349 487 5.27E-43 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS01470 5b81dfe94dd4d5b53a47a58f2b8ab8eb 494 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 355 485 7.9E-20 T 22-04-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS01470 5b81dfe94dd4d5b53a47a58f2b8ab8eb 494 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 210 341 1.0E-23 T 22-04-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS01470 5b81dfe94dd4d5b53a47a58f2b8ab8eb 494 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 35 367 8.6E-125 T 22-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS01470 5b81dfe94dd4d5b53a47a58f2b8ab8eb 494 Gene3D G3DSA:3.40.50.720 1 201 9.6E-75 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01470 5b81dfe94dd4d5b53a47a58f2b8ab8eb 494 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 22 488 37.415 T 22-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 TIGRFAM TIGR02038 protease_degS: periplasmic serine peptidase DegS 6 358 3.7E-132 T 22-04-2016 IPR011783 Peptidase S1C, DegS GO:0004252|GO:0006508 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 Pfam PF13365 Trypsin-like peptidase domain 83 222 7.0E-30 T 22-04-2016 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 Gene3D G3DSA:2.30.42.10 265 356 3.9E-21 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 PANTHER PTHR22939:SF93 1 357 1.3E-136 T 22-04-2016 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 SUPERFAMILY SSF50494 41 271 5.93E-56 T 22-04-2016 IPR009003 Peptidase S1, PA clan TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 Gene3D G3DSA:2.40.10.10 41 144 1.1E-28 T 22-04-2016 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 PRINTS PR00834 HtrA/DegQ protease family signature 215 232 1.1E-44 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 PRINTS PR00834 HtrA/DegQ protease family signature 303 315 1.1E-44 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 PRINTS PR00834 HtrA/DegQ protease family signature 193 210 1.1E-44 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 PRINTS PR00834 HtrA/DegQ protease family signature 153 177 1.1E-44 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 PRINTS PR00834 HtrA/DegQ protease family signature 92 104 1.1E-44 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 PRINTS PR00834 HtrA/DegQ protease family signature 113 133 1.1E-44 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 Gene3D G3DSA:2.40.10.10 152 264 1.1E-36 T 22-04-2016 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 SUPERFAMILY SSF50156 246 353 4.99E-21 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 SMART SM00228 263 345 9.9E-11 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 PANTHER PTHR22939 1 357 1.3E-136 T 22-04-2016 TOLA_RS15005 a4a67122fdcf3c09ad9b9a09a84156fd 366 Pfam PF13180 PDZ domain 264 354 3.0E-14 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS02240 f33077813dfd6cd561433559a7c2dbfd 458 ProSitePatterns PS00455 Putative AMP-binding domain signature. 133 144 - T 22-04-2016 IPR020845 AMP-binding, conserved site TOLA_RS02240 f33077813dfd6cd561433559a7c2dbfd 458 SUPERFAMILY SSF56801 8 449 1.07E-102 T 22-04-2016 TOLA_RS02240 f33077813dfd6cd561433559a7c2dbfd 458 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 29 444 8.1E-106 T 22-04-2016 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 TOLA_RS02240 f33077813dfd6cd561433559a7c2dbfd 458 PANTHER PTHR24096:SF109 7 433 4.3E-123 T 22-04-2016 TOLA_RS02240 f33077813dfd6cd561433559a7c2dbfd 458 Gene3D G3DSA:2.30.38.10 300 351 5.6E-11 T 22-04-2016 TOLA_RS02240 f33077813dfd6cd561433559a7c2dbfd 458 Pfam PF00501 AMP-binding enzyme 9 357 6.1E-59 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 TOLA_RS02240 f33077813dfd6cd561433559a7c2dbfd 458 PANTHER PTHR24096 7 433 4.3E-123 T 22-04-2016 TOLA_RS02240 f33077813dfd6cd561433559a7c2dbfd 458 Pfam PF13193 AMP-binding enzyme C-terminal domain 367 434 7.4E-10 T 22-04-2016 IPR025110 AMP-binding enzyme C-terminal domain TOLA_RS02240 f33077813dfd6cd561433559a7c2dbfd 458 Gene3D G3DSA:3.30.300.30 352 448 1.7E-21 T 22-04-2016 TOLA_RS02240 f33077813dfd6cd561433559a7c2dbfd 458 Gene3D G3DSA:3.40.50.980 8 142 4.2E-25 T 22-04-2016 TOLA_RS02240 f33077813dfd6cd561433559a7c2dbfd 458 Gene3D G3DSA:3.40.50.980 143 291 6.5E-26 T 22-04-2016 TOLA_RS00895 657e97e8615083b927248b685d95c0f7 168 SUPERFAMILY SSF51197 1 163 7.14E-27 T 22-04-2016 TOLA_RS00895 657e97e8615083b927248b685d95c0f7 168 Gene3D G3DSA:2.60.120.370 1 163 3.1E-40 T 22-04-2016 IPR004375 YhcH/YjgK/YiaL family TOLA_RS00895 657e97e8615083b927248b685d95c0f7 168 PANTHER PTHR34986 2 165 6.9E-28 T 22-04-2016 TOLA_RS00895 657e97e8615083b927248b685d95c0f7 168 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 1 163 1.5E-25 T 22-04-2016 IPR004375 YhcH/YjgK/YiaL family TOLA_RS00895 657e97e8615083b927248b685d95c0f7 168 Pfam PF04074 Domain of unknown function (DUF386) 1 160 1.6E-33 T 22-04-2016 IPR004375 YhcH/YjgK/YiaL family TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PANTHER PTHR30477 23 312 2.5E-78 T 22-04-2016 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 SUPERFAMILY SSF53807 22 313 1.81E-90 T 22-04-2016 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PRINTS PR00690 Adhesin family signature 278 297 1.5E-23 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PRINTS PR00690 Adhesin family signature 26 44 1.5E-23 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PRINTS PR00690 Adhesin family signature 57 70 1.5E-23 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PRINTS PR00690 Adhesin family signature 199 220 1.5E-23 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PRINTS PR00690 Adhesin family signature 252 270 1.5E-23 T 22-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 Gene3D G3DSA:3.40.50.1980 192 313 1.6E-45 T 22-04-2016 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 Pfam PF01297 Zinc-uptake complex component A periplasmic 29 308 1.0E-83 T 22-04-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PRINTS PR00691 Adhesin B signature 199 216 1.3E-21 T 22-04-2016 IPR006129 Adhesin B GO:0007155 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PRINTS PR00691 Adhesin B signature 270 288 1.3E-21 T 22-04-2016 IPR006129 Adhesin B GO:0007155 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PRINTS PR00691 Adhesin B signature 248 265 1.3E-21 T 22-04-2016 IPR006129 Adhesin B GO:0007155 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PRINTS PR00691 Adhesin B signature 26 47 1.3E-21 T 22-04-2016 IPR006129 Adhesin B GO:0007155 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PRINTS PR00691 Adhesin B signature 51 69 1.3E-21 T 22-04-2016 IPR006129 Adhesin B GO:0007155 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PRINTS PR00691 Adhesin B signature 291 309 1.3E-21 T 22-04-2016 IPR006129 Adhesin B GO:0007155 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 PANTHER PTHR30477:SF16 23 312 2.5E-78 T 22-04-2016 TOLA_RS14955 49787c4fc9143d78e9440245830c3c8e 314 Gene3D G3DSA:3.40.50.1980 22 191 3.6E-56 T 22-04-2016 TOLA_RS15900 1c9f33da104907d1cea7ec8a7b864a36 317 Gene3D G3DSA:3.40.190.10 103 187 1.0E-18 T 22-04-2016 TOLA_RS15900 1c9f33da104907d1cea7ec8a7b864a36 317 Gene3D G3DSA:3.40.190.10 287 313 1.0E-18 T 22-04-2016 TOLA_RS15900 1c9f33da104907d1cea7ec8a7b864a36 317 Pfam PF03466 LysR substrate binding domain 108 311 9.6E-25 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS15900 1c9f33da104907d1cea7ec8a7b864a36 317 PANTHER PTHR30118 10 313 3.5E-52 T 22-04-2016 TOLA_RS15900 1c9f33da104907d1cea7ec8a7b864a36 317 SUPERFAMILY SSF53850 103 310 2.17E-29 T 22-04-2016 TOLA_RS15900 1c9f33da104907d1cea7ec8a7b864a36 317 Gene3D G3DSA:3.40.190.10 194 281 2.3E-8 T 22-04-2016 TOLA_RS15900 1c9f33da104907d1cea7ec8a7b864a36 317 Gene3D G3DSA:1.10.10.10 14 98 1.1E-27 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15900 1c9f33da104907d1cea7ec8a7b864a36 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 22 79 6.9E-14 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS15900 1c9f33da104907d1cea7ec8a7b864a36 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 58 69 5.7E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS15900 1c9f33da104907d1cea7ec8a7b864a36 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 58 5.7E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS15900 1c9f33da104907d1cea7ec8a7b864a36 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 48 5.7E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS15900 1c9f33da104907d1cea7ec8a7b864a36 317 SUPERFAMILY SSF46785 16 96 6.61E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11925 2204c7bdf0c114bdfccf0cdeaaacbbda 290 PANTHER PTHR10907 7 288 1.2E-75 T 22-04-2016 TOLA_RS11925 2204c7bdf0c114bdfccf0cdeaaacbbda 290 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 237 255 1.6E-32 T 22-04-2016 IPR005511 Senescence marker protein-30 (SMP-30) TOLA_RS11925 2204c7bdf0c114bdfccf0cdeaaacbbda 290 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 195 212 1.6E-32 T 22-04-2016 IPR005511 Senescence marker protein-30 (SMP-30) TOLA_RS11925 2204c7bdf0c114bdfccf0cdeaaacbbda 290 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 89 110 1.6E-32 T 22-04-2016 IPR005511 Senescence marker protein-30 (SMP-30) TOLA_RS11925 2204c7bdf0c114bdfccf0cdeaaacbbda 290 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 12 29 1.6E-32 T 22-04-2016 IPR005511 Senescence marker protein-30 (SMP-30) TOLA_RS11925 2204c7bdf0c114bdfccf0cdeaaacbbda 290 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 153 173 1.6E-32 T 22-04-2016 IPR005511 Senescence marker protein-30 (SMP-30) TOLA_RS11925 2204c7bdf0c114bdfccf0cdeaaacbbda 290 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 130 152 1.6E-32 T 22-04-2016 IPR005511 Senescence marker protein-30 (SMP-30) TOLA_RS11925 2204c7bdf0c114bdfccf0cdeaaacbbda 290 PANTHER PTHR10907:SF47 7 288 1.2E-75 T 22-04-2016 TOLA_RS11925 2204c7bdf0c114bdfccf0cdeaaacbbda 290 SUPERFAMILY SSF63829 7 288 1.37E-62 T 22-04-2016 TOLA_RS11925 2204c7bdf0c114bdfccf0cdeaaacbbda 290 Gene3D G3DSA:2.120.10.30 5 289 8.1E-88 T 22-04-2016 IPR011042 Six-bladed beta-propeller, TolB-like TOLA_RS11925 2204c7bdf0c114bdfccf0cdeaaacbbda 290 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 11 255 1.5E-78 T 22-04-2016 IPR013658 SMP-30/Gluconolactonase/LRE-like region TOLA_RS14980 8357373ccaf0fa994fbc9f8ec609bca4 112 SUPERFAMILY SSF54913 1 112 8.9E-47 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta TOLA_RS14980 8357373ccaf0fa994fbc9f8ec609bca4 112 Gene3D G3DSA:3.30.70.120 1 112 6.9E-53 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TOLA_RS14980 8357373ccaf0fa994fbc9f8ec609bca4 112 PANTHER PTHR30115 1 112 4.9E-69 T 22-04-2016 TOLA_RS14980 8357373ccaf0fa994fbc9f8ec609bca4 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 22-04-2016 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 TOLA_RS14980 8357373ccaf0fa994fbc9f8ec609bca4 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 22-04-2016 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 TOLA_RS14980 8357373ccaf0fa994fbc9f8ec609bca4 112 PIRSF PIRSF039144 1 112 2.9E-57 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS14980 8357373ccaf0fa994fbc9f8ec609bca4 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.0E-44 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS14980 8357373ccaf0fa994fbc9f8ec609bca4 112 SMART SM00938 4 105 2.4E-69 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS14980 8357373ccaf0fa994fbc9f8ec609bca4 112 PRINTS PR00340 P-II protein signature 2 17 4.4E-45 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS14980 8357373ccaf0fa994fbc9f8ec609bca4 112 PRINTS PR00340 P-II protein signature 52 75 4.4E-45 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS14980 8357373ccaf0fa994fbc9f8ec609bca4 112 PRINTS PR00340 P-II protein signature 83 103 4.4E-45 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS14980 8357373ccaf0fa994fbc9f8ec609bca4 112 PRINTS PR00340 P-II protein signature 23 41 4.4E-45 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS12190 ccfab1679a3a618762b55e6c199f5c11 287 SUPERFAMILY SSF52540 1 259 1.54E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12190 ccfab1679a3a618762b55e6c199f5c11 287 Pfam PF13614 AAA domain 1 158 9.9E-30 T 22-04-2016 IPR025669 AAA domain TOLA_RS12190 ccfab1679a3a618762b55e6c199f5c11 287 PANTHER PTHR13696 1 270 1.6E-32 T 22-04-2016 TOLA_RS12190 ccfab1679a3a618762b55e6c199f5c11 287 Gene3D G3DSA:3.40.50.300 1 266 4.5E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 Pfam PF12848 ABC transporter 217 298 6.0E-26 T 22-04-2016 IPR032781 ABC-transporter extension domain TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 PANTHER PTHR19211:SF49 1 557 0.0 T 22-04-2016 TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 PANTHER PTHR19211 1 557 0.0 T 22-04-2016 TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 Gene3D G3DSA:3.40.50.300 311 532 1.0E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 SMART SM00382 26 223 2.0E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 SMART SM00382 337 505 4.5E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 SUPERFAMILY SSF52540 294 515 3.11E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 Pfam PF00005 ABC transporter 18 178 2.6E-21 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 Pfam PF00005 ABC transporter 328 459 8.0E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 SUPERFAMILY SSF52540 119 243 2.05E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 SUPERFAMILY SSF52540 2 92 2.05E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 Gene3D G3DSA:3.40.50.300 6 274 1.5E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04390 1b5830cd260bd15e60724ce386afb015 645 Pfam PF16326 ABC transporter C-terminal domain 563 628 1.9E-9 T 22-04-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 PANTHER PTHR10169 5 527 0.0 T 22-04-2016 TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 35 467 2.0E-135 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 Gene3D G3DSA:2.120.10.90 499 742 4.9E-27 T 22-04-2016 TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 Gene3D G3DSA:3.90.199.10 336 401 1.3E-105 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 Gene3D G3DSA:3.90.199.10 33 240 1.3E-105 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 SUPERFAMILY SSF101904 505 745 2.49E-50 T 22-04-2016 TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 SUPERFAMILY SSF56719 34 486 1.29E-154 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 7 747 33.677 T 22-04-2016 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 652 701 3.3E-6 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 PANTHER PTHR10169:SF30 5 527 0.0 T 22-04-2016 TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 SMART SM00434 14 464 1.1E-226 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 Gene3D G3DSA:3.30.1360.40 241 334 2.1E-24 T 22-04-2016 IPR024946 Arginine repressor C-terminal-like domain TOLA_RS02405 cb607a13e195a2d8da57c31c0388972a 759 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 11 747 0.0 T 22-04-2016 TOLA_RS02060 c4cf360fdac714b436562dea2c6a022a 147 PANTHER PTHR38774 2 147 8.2E-44 T 22-04-2016 TOLA_RS02060 c4cf360fdac714b436562dea2c6a022a 147 Pfam PF06853 Protein of unknown function (DUF1249) 28 141 2.4E-42 T 22-04-2016 IPR009659 Protein of unknown function DUF1249 TOLA_RS02060 c4cf360fdac714b436562dea2c6a022a 147 PANTHER PTHR38774:SF1 2 147 8.2E-44 T 22-04-2016 TOLA_RS13530 e209fdeadf0e991d46a521abdccefe82 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 22-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 TOLA_RS13530 e209fdeadf0e991d46a521abdccefe82 108 PIRSF PIRSF000077 2 108 1.1E-44 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TOLA_RS13530 e209fdeadf0e991d46a521abdccefe82 108 SUPERFAMILY SSF52833 2 108 3.72E-40 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS13530 e209fdeadf0e991d46a521abdccefe82 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 5.2E-38 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TOLA_RS13530 e209fdeadf0e991d46a521abdccefe82 108 PRINTS PR00421 Thioredoxin family signature 32 41 3.3E-10 T 22-04-2016 TOLA_RS13530 e209fdeadf0e991d46a521abdccefe82 108 PRINTS PR00421 Thioredoxin family signature 72 83 3.3E-10 T 22-04-2016 TOLA_RS13530 e209fdeadf0e991d46a521abdccefe82 108 PRINTS PR00421 Thioredoxin family signature 24 32 3.3E-10 T 22-04-2016 TOLA_RS13530 e209fdeadf0e991d46a521abdccefe82 108 PANTHER PTHR10438 3 108 2.2E-37 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TOLA_RS13530 e209fdeadf0e991d46a521abdccefe82 108 Gene3D G3DSA:3.40.30.10 2 107 5.5E-40 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS13530 e209fdeadf0e991d46a521abdccefe82 108 Pfam PF00085 Thioredoxin 5 107 7.4E-34 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 TOLA_RS12665 fdd80c67401398808d41e0a6b455c48a 181 Pfam PF00929 Exonuclease 9 170 2.3E-35 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III TOLA_RS12665 fdd80c67401398808d41e0a6b455c48a 181 Gene3D G3DSA:3.30.420.10 4 179 1.8E-73 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS12665 fdd80c67401398808d41e0a6b455c48a 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 42.816 T 22-04-2016 IPR022894 Oligoribonuclease GO:0016788 TOLA_RS12665 fdd80c67401398808d41e0a6b455c48a 181 SMART SM00479 7 180 1.4E-21 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III TOLA_RS12665 fdd80c67401398808d41e0a6b455c48a 181 SUPERFAMILY SSF53098 3 179 8.54E-47 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS12665 fdd80c67401398808d41e0a6b455c48a 181 PANTHER PTHR11046:SF1 3 181 1.2E-110 T 22-04-2016 TOLA_RS12665 fdd80c67401398808d41e0a6b455c48a 181 PANTHER PTHR11046 3 181 1.2E-110 T 22-04-2016 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 Pfam PF01225 Mur ligase family, catalytic domain 2 101 1.7E-20 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 SUPERFAMILY SSF53244 312 448 1.7E-35 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 Pfam PF08245 Mur ligase middle domain 108 292 2.3E-18 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 PANTHER PTHR23135:SF17 1 449 5.9E-265 T 22-04-2016 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 PANTHER PTHR23135 1 449 5.9E-265 T 22-04-2016 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 Gene3D G3DSA:3.40.1190.10 92 311 3.5E-79 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 450 58.955 T 22-04-2016 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 UniPathway: UPA00544 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 449 4.6E-227 T 22-04-2016 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 UniPathway: UPA00544 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 SUPERFAMILY SSF51984 1 90 1.14E-24 T 22-04-2016 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 Gene3D G3DSA:3.90.190.20 313 450 8.9E-34 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 Pfam PF02875 Mur ligase family, glutamate ligase domain 313 360 1.3E-7 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 SUPERFAMILY SSF53623 97 309 4.58E-49 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS12930 2a0609805a9c0bc93e4c6d73e666dbca 456 Gene3D G3DSA:3.40.50.720 1 90 7.1E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS12925 02de8621366fb2f53c5a96763c77dbc8 200 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 3 200 35.168 T 22-04-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 TOLA_RS12925 02de8621366fb2f53c5a96763c77dbc8 200 Gene3D G3DSA:3.40.50.1950 4 199 5.0E-74 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 TOLA_RS12925 02de8621366fb2f53c5a96763c77dbc8 200 SUPERFAMILY SSF52507 5 199 1.1E-59 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 TOLA_RS12925 02de8621366fb2f53c5a96763c77dbc8 200 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 5 198 1.3E-60 T 22-04-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 TOLA_RS12925 02de8621366fb2f53c5a96763c77dbc8 200 Pfam PF02441 Flavoprotein 5 143 7.4E-29 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 TOLA_RS12925 02de8621366fb2f53c5a96763c77dbc8 200 PANTHER PTHR30108 67 198 4.6E-80 T 22-04-2016 TOLA_RS12925 02de8621366fb2f53c5a96763c77dbc8 200 PANTHER PTHR30108 2 50 4.6E-80 T 22-04-2016 TOLA_RS12925 02de8621366fb2f53c5a96763c77dbc8 200 PANTHER PTHR30108:SF2 67 198 4.6E-80 T 22-04-2016 TOLA_RS12925 02de8621366fb2f53c5a96763c77dbc8 200 PANTHER PTHR30108:SF2 2 50 4.6E-80 T 22-04-2016 TOLA_RS02550 fd36579d7a04916a15fb0f5951a781e5 748 SUPERFAMILY SSF48452 81 118 4.46E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS02550 fd36579d7a04916a15fb0f5951a781e5 748 SUPERFAMILY SSF48452 182 283 4.46E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS02550 fd36579d7a04916a15fb0f5951a781e5 748 Pfam PF13424 Tetratricopeptide repeat 327 395 2.2E-8 T 22-04-2016 TOLA_RS02550 fd36579d7a04916a15fb0f5951a781e5 748 SUPERFAMILY SSF48452 250 432 6.07E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS02550 fd36579d7a04916a15fb0f5951a781e5 748 Gene3D G3DSA:1.25.40.10 215 434 3.8E-17 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS02550 fd36579d7a04916a15fb0f5951a781e5 748 Gene3D G3DSA:1.25.40.10 90 111 3.8E-17 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS02550 fd36579d7a04916a15fb0f5951a781e5 748 SMART SM00028 85 118 18.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS02550 fd36579d7a04916a15fb0f5951a781e5 748 SMART SM00028 328 361 1.6 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS02550 fd36579d7a04916a15fb0f5951a781e5 748 SMART SM00028 248 281 120.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS13130 7a0d49406814e877dbc8ae0fa618bca6 445 SUPERFAMILY SSF54826 7 136 1.18E-31 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TOLA_RS13130 7a0d49406814e877dbc8ae0fa618bca6 445 Gene3D G3DSA:3.20.20.120 122 397 2.5E-101 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS13130 7a0d49406814e877dbc8ae0fa618bca6 445 PANTHER PTHR13794 6 151 2.5E-292 T 22-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 TOLA_RS13130 7a0d49406814e877dbc8ae0fa618bca6 445 PANTHER PTHR13794 172 430 2.5E-292 T 22-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 TOLA_RS13130 7a0d49406814e877dbc8ae0fa618bca6 445 Pfam PF13378 Enolase C-terminal domain-like 188 404 3.5E-35 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS13130 7a0d49406814e877dbc8ae0fa618bca6 445 SMART SM00922 184 284 6.9E-16 T 22-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TOLA_RS13130 7a0d49406814e877dbc8ae0fa618bca6 445 TIGRFAM TIGR03247 glucar-dehydr: glucarate dehydratase 5 445 8.6E-263 T 22-04-2016 IPR017653 Glucarate dehydratase GO:0000287|GO:0008872|GO:0019394 KEGG: 00053+4.2.1.40|MetaCyc: PWY-6499|UniPathway: UPA00564 TOLA_RS13130 7a0d49406814e877dbc8ae0fa618bca6 445 SUPERFAMILY SSF51604 138 415 6.92E-82 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS13130 7a0d49406814e877dbc8ae0fa618bca6 445 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 42 136 1.6E-5 T 22-04-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TOLA_RS13130 7a0d49406814e877dbc8ae0fa618bca6 445 PANTHER PTHR13794:SF47 6 151 2.5E-292 T 22-04-2016 TOLA_RS13130 7a0d49406814e877dbc8ae0fa618bca6 445 PANTHER PTHR13794:SF47 172 430 2.5E-292 T 22-04-2016 TOLA_RS13130 7a0d49406814e877dbc8ae0fa618bca6 445 Gene3D G3DSA:3.30.390.10 34 121 5.7E-10 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TOLA_RS14485 36a2e9c465c4809cd738e864c7c5f9dc 111 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 9.3E-28 T 22-04-2016 TOLA_RS14485 36a2e9c465c4809cd738e864c7c5f9dc 111 SUPERFAMILY SSF81301 4 106 2.29E-37 T 22-04-2016 TOLA_RS14485 36a2e9c465c4809cd738e864c7c5f9dc 111 PANTHER PTHR21043 1 104 2.6E-41 T 22-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS TOLA_RS14485 36a2e9c465c4809cd738e864c7c5f9dc 111 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 1.1E-36 T 22-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS TOLA_RS14485 36a2e9c465c4809cd738e864c7c5f9dc 111 Gene3D G3DSA:3.30.460.10 4 106 4.9E-38 T 22-04-2016 TOLA_RS14485 36a2e9c465c4809cd738e864c7c5f9dc 111 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 23.627 T 22-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 Pfam PF09334 tRNA synthetases class I (M) 8 396 2.8E-163 T 22-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 Pfam PF01588 Putative tRNA binding domain 580 672 5.6E-24 T 22-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 Gene3D G3DSA:3.40.50.620 183 379 8.4E-87 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 Gene3D G3DSA:3.40.50.620 6 144 8.4E-87 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 8 535 5.3E-200 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 Gene3D G3DSA:2.40.50.140 568 675 4.2E-41 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 7.2E-26 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 7.2E-26 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 PRINTS PR01041 Methionyl-tRNA synthetase signature 291 306 7.2E-26 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 7.2E-26 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 PRINTS PR01041 Methionyl-tRNA synthetase signature 251 262 7.2E-26 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 PRINTS PR01041 Methionyl-tRNA synthetase signature 384 395 7.2E-26 T 22-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 Gene3D G3DSA:1.10.730.10 380 534 1.8E-45 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 PANTHER PTHR11946:SF86 6 630 3.3E-253 T 22-04-2016 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 545 675 1.6E-45 T 22-04-2016 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 SUPERFAMILY SSF50249 569 674 3.67E-32 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 SUPERFAMILY SSF52374 176 387 2.82E-100 T 22-04-2016 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 SUPERFAMILY SSF52374 6 141 2.82E-100 T 22-04-2016 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 Hamap MF_00098 Methionine--tRNA ligase [metG]. 6 545 41.001 T 22-04-2016 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 SUPERFAMILY SSF57770 142 176 8.63E-13 T 22-04-2016 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 PANTHER PTHR11946 6 630 3.3E-253 T 22-04-2016 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 Gene3D G3DSA:2.20.28.20 145 176 7.7E-20 T 22-04-2016 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TOLA_RS07795 b30859ce729c338b428fdf2e71eb0466 675 SUPERFAMILY SSF47323 389 546 2.24E-46 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS14395 2a49aa6b8f162f2ffa8ddd4cfc2f61b6 171 ProDom PD095266 MEMBRANE YFGI EXPORTED 83 168 2.0E-18 T 22-04-2016 IPR020231 Uncharacterised protein family, YfgI TOLA_RS12985 244b221c11b20f682e89634e20402d5a 549 PANTHER PTHR30389 3 547 0.0 T 22-04-2016 TOLA_RS12985 244b221c11b20f682e89634e20402d5a 549 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 74 325 1.5E-30 T 22-04-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 TOLA_RS12985 244b221c11b20f682e89634e20402d5a 549 Pfam PF05681 Fumarate hydratase (Fumerase) 51 326 2.1E-86 T 22-04-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 TOLA_RS12985 244b221c11b20f682e89634e20402d5a 549 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 373 537 5.5E-62 T 22-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TOLA_RS12985 244b221c11b20f682e89634e20402d5a 549 ProSitePatterns PS00163 Fumarate lyases signature. 456 465 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 TOLA_RS12985 244b221c11b20f682e89634e20402d5a 549 PANTHER PTHR30389:SF6 3 547 0.0 T 22-04-2016 TOLA_RS12985 244b221c11b20f682e89634e20402d5a 549 Pfam PF05683 Fumarase C-terminus 332 537 1.2E-93 T 22-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TOLA_RS12985 244b221c11b20f682e89634e20402d5a 549 PIRSF PIRSF001394 30 549 1.5E-233 T 22-04-2016 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS12985 244b221c11b20f682e89634e20402d5a 549 SUPERFAMILY SSF117457 361 536 6.41E-62 T 22-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TOLA_RS12985 244b221c11b20f682e89634e20402d5a 549 Gene3D G3DSA:3.20.130.10 348 537 2.5E-75 T 22-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 SUPERFAMILY SSF53067 158 392 4.29E-89 T 22-04-2016 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 PIRSF PIRSF000722 1 392 2.7E-154 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 Pfam PF00871 Acetokinase family 4 387 1.4E-155 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 PRINTS PR00471 Acetate kinase family signature 374 386 4.6E-43 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 PRINTS PR00471 Acetate kinase family signature 300 313 4.6E-43 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 PRINTS PR00471 Acetate kinase family signature 203 224 4.6E-43 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 PRINTS PR00471 Acetate kinase family signature 5 16 4.6E-43 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 PRINTS PR00471 Acetate kinase family signature 173 186 4.6E-43 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 PRINTS PR00471 Acetate kinase family signature 322 338 4.6E-43 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 203 220 - T 22-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 22-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 Gene3D G3DSA:3.30.420.40 4 204 8.0E-11 T 22-04-2016 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 PANTHER PTHR21060 1 392 1.5E-206 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 Hamap MF_00020 Acetate kinase [ackA]. 1 392 181.234 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 Hamap MF_01882 Probable propionate kinase [pduW]. 1 392 77.52 T 22-04-2016 IPR024896 Propionate kinase PduW GO:0008980|GO:0019543|GO:0051144 KEGG: 00640+2.7.2.15|MetaCyc: PWY-5437|MetaCyc: PWY-7013 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 Gene3D G3DSA:3.30.420.40 205 391 4.6E-80 T 22-04-2016 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 TIGRFAM TIGR00016 ackA: acetate kinase 3 392 1.2E-164 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 SUPERFAMILY SSF53067 3 194 3.15E-67 T 22-04-2016 TOLA_RS08660 2e4e8a800a15b4e5a354505d7ceac248 392 PANTHER PTHR21060:SF11 1 392 1.5E-206 T 22-04-2016 TOLA_RS00965 054b77e5773df6d6ea17f029054bdaee 55 Pfam PF00471 Ribosomal protein L33 7 53 2.4E-17 T 22-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00965 054b77e5773df6d6ea17f029054bdaee 55 SUPERFAMILY SSF57829 1 53 3.97E-19 T 22-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 TOLA_RS00965 054b77e5773df6d6ea17f029054bdaee 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 22-04-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00965 054b77e5773df6d6ea17f029054bdaee 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 5.3E-27 T 22-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00965 054b77e5773df6d6ea17f029054bdaee 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 15.13 T 22-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00965 054b77e5773df6d6ea17f029054bdaee 55 PANTHER PTHR15238 1 55 4.7E-23 T 22-04-2016 TOLA_RS01490 c9a7f31f95b08a4babf8f6154e992e16 639 Gene3D G3DSA:3.40.50.10370 379 468 2.8E-40 T 22-04-2016 IPR029503 Phosphotransferase system EIIB component, mannitol-specific GO:0009401|GO:0022872 TOLA_RS01490 c9a7f31f95b08a4babf8f6154e992e16 639 SUPERFAMILY SSF52794 379 467 6.8E-25 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS01490 c9a7f31f95b08a4babf8f6154e992e16 639 PANTHER PTHR30181:SF2 1 610 0.0 T 22-04-2016 TOLA_RS01490 c9a7f31f95b08a4babf8f6154e992e16 639 SUPERFAMILY SSF55804 496 635 5.76E-39 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 TOLA_RS01490 c9a7f31f95b08a4babf8f6154e992e16 639 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 539 555 - T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS01490 c9a7f31f95b08a4babf8f6154e992e16 639 Gene3D G3DSA:3.40.930.10 496 634 1.5E-41 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS01490 c9a7f31f95b08a4babf8f6154e992e16 639 PANTHER PTHR30181 1 610 0.0 T 22-04-2016 TOLA_RS01490 c9a7f31f95b08a4babf8f6154e992e16 639 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 497 634 6.1E-31 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS01490 c9a7f31f95b08a4babf8f6154e992e16 639 Pfam PF02378 Phosphotransferase system, EIIC 18 277 1.6E-18 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS01490 c9a7f31f95b08a4babf8f6154e992e16 639 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 381 462 5.2E-12 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS01490 c9a7f31f95b08a4babf8f6154e992e16 639 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 9 346 6.7E-169 T 22-04-2016 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 TOLA_RS15075 4c4e408c37a288136a40ad0e2a844eae 95 SUPERFAMILY SSF69754 1 95 4.32E-34 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 TOLA_RS15075 4c4e408c37a288136a40ad0e2a844eae 95 PANTHER PTHR33231 1 92 2.9E-37 T 22-04-2016 TOLA_RS15075 4c4e408c37a288136a40ad0e2a844eae 95 Gene3D G3DSA:3.30.160.100 1 94 5.9E-37 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 TOLA_RS15075 4c4e408c37a288136a40ad0e2a844eae 95 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 92 1.4E-27 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 TOLA_RS15075 4c4e408c37a288136a40ad0e2a844eae 95 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 94 1.5E-32 T 22-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 TOLA_RS08405 b6fcf72f0feefffffb55e2de80dcc50a 257 Pfam PF00455 DeoR C terminal sensor domain 77 228 3.9E-40 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain TOLA_RS08405 b6fcf72f0feefffffb55e2de80dcc50a 257 PANTHER PTHR30363 1 253 4.8E-63 T 22-04-2016 TOLA_RS08405 b6fcf72f0feefffffb55e2de80dcc50a 257 SUPERFAMILY SSF100950 75 230 6.49E-26 T 22-04-2016 TOLA_RS08405 b6fcf72f0feefffffb55e2de80dcc50a 257 SMART SM00420 6 58 1.5E-7 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS08405 b6fcf72f0feefffffb55e2de80dcc50a 257 Gene3D G3DSA:1.10.10.10 1 60 2.3E-4 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08405 b6fcf72f0feefffffb55e2de80dcc50a 257 SUPERFAMILY SSF46785 4 76 2.08E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08405 b6fcf72f0feefffffb55e2de80dcc50a 257 PANTHER PTHR30363:SF13 1 253 4.8E-63 T 22-04-2016 TOLA_RS08405 b6fcf72f0feefffffb55e2de80dcc50a 257 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 6.6E-11 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS08405 b6fcf72f0feefffffb55e2de80dcc50a 257 SMART SM01134 71 229 8.7E-48 T 22-04-2016 TOLA_RS08405 b6fcf72f0feefffffb55e2de80dcc50a 257 Gene3D G3DSA:3.40.50.1360 76 212 4.1E-9 T 22-04-2016 TOLA_RS07225 ccf9104323fb38bd273df69b8222d7e2 489 SUPERFAMILY SSF51182 182 467 2.83E-77 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS07225 ccf9104323fb38bd273df69b8222d7e2 489 Pfam PF01050 Mannose-6-phosphate isomerase 312 462 1.0E-61 T 22-04-2016 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07225 ccf9104323fb38bd273df69b8222d7e2 489 SUPERFAMILY SSF53448 1 277 1.06E-70 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS07225 ccf9104323fb38bd273df69b8222d7e2 489 PANTHER PTHR12526 151 286 1.2E-98 T 22-04-2016 TOLA_RS07225 ccf9104323fb38bd273df69b8222d7e2 489 PANTHER PTHR12526 349 487 1.2E-98 T 22-04-2016 TOLA_RS07225 ccf9104323fb38bd273df69b8222d7e2 489 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 1 466 1.6E-207 T 22-04-2016 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS07225 ccf9104323fb38bd273df69b8222d7e2 489 Gene3D G3DSA:3.90.550.10 1 268 7.5E-95 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS07225 ccf9104323fb38bd273df69b8222d7e2 489 PANTHER PTHR12526:SF387 151 286 1.2E-98 T 22-04-2016 TOLA_RS07225 ccf9104323fb38bd273df69b8222d7e2 489 PANTHER PTHR12526:SF387 349 487 1.2E-98 T 22-04-2016 TOLA_RS07225 ccf9104323fb38bd273df69b8222d7e2 489 Pfam PF00483 Nucleotidyl transferase 3 283 5.5E-70 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 TOLA_RS07225 ccf9104323fb38bd273df69b8222d7e2 489 Gene3D G3DSA:2.60.120.10 354 468 1.2E-41 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS04560 72b4c899cbf93bf85d3f986a59475d27 425 PIRSF PIRSF001549 2 423 2.9E-122 T 22-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 TOLA_RS04560 72b4c899cbf93bf85d3f986a59475d27 425 Gene3D G3DSA:3.30.930.10 221 320 1.6E-93 T 22-04-2016 TOLA_RS04560 72b4c899cbf93bf85d3f986a59475d27 425 Gene3D G3DSA:3.30.930.10 4 185 1.6E-93 T 22-04-2016 TOLA_RS04560 72b4c899cbf93bf85d3f986a59475d27 425 Pfam PF03129 Anticodon binding domain 347 421 1.2E-8 T 22-04-2016 IPR004154 Anticodon-binding TOLA_RS04560 72b4c899cbf93bf85d3f986a59475d27 425 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 411 5.5E-156 T 22-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 TOLA_RS04560 72b4c899cbf93bf85d3f986a59475d27 425 PANTHER PTHR11476:SF9 2 423 1.7E-219 T 22-04-2016 TOLA_RS04560 72b4c899cbf93bf85d3f986a59475d27 425 SUPERFAMILY SSF55681 5 324 2.39E-100 T 22-04-2016 TOLA_RS04560 72b4c899cbf93bf85d3f986a59475d27 425 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 422 32.782 T 22-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 TOLA_RS04560 72b4c899cbf93bf85d3f986a59475d27 425 Pfam PF13393 Histidyl-tRNA synthetase 10 312 4.4E-45 T 22-04-2016 TOLA_RS04560 72b4c899cbf93bf85d3f986a59475d27 425 PANTHER PTHR11476 2 423 1.7E-219 T 22-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 TOLA_RS04560 72b4c899cbf93bf85d3f986a59475d27 425 Gene3D G3DSA:3.40.50.800 326 420 1.3E-27 T 22-04-2016 IPR004154 Anticodon-binding TOLA_RS04560 72b4c899cbf93bf85d3f986a59475d27 425 SUPERFAMILY SSF52954 327 422 1.41E-20 T 22-04-2016 IPR004154 Anticodon-binding TOLA_RS09880 e5b5357b33b403319532c0f26541ebc7 504 ProSitePatterns PS00211 ABC transporters family signature. 397 411 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS09880 e5b5357b33b403319532c0f26541ebc7 504 Pfam PF00005 ABC transporter 273 424 9.8E-21 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS09880 e5b5357b33b403319532c0f26541ebc7 504 Pfam PF00005 ABC transporter 22 172 9.1E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS09880 e5b5357b33b403319532c0f26541ebc7 504 SUPERFAMILY SSF52540 6 229 1.22E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09880 e5b5357b33b403319532c0f26541ebc7 504 SMART SM00382 279 473 1.3E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS09880 e5b5357b33b403319532c0f26541ebc7 504 SMART SM00382 30 228 1.1E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS09880 e5b5357b33b403319532c0f26541ebc7 504 PANTHER PTHR24220 7 379 1.3E-136 T 22-04-2016 TOLA_RS09880 e5b5357b33b403319532c0f26541ebc7 504 Gene3D G3DSA:3.40.50.300 5 230 2.7E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09880 e5b5357b33b403319532c0f26541ebc7 504 Gene3D G3DSA:3.40.50.300 257 493 9.8E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09880 e5b5357b33b403319532c0f26541ebc7 504 SUPERFAMILY SSF52540 268 491 3.2E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09880 e5b5357b33b403319532c0f26541ebc7 504 PANTHER PTHR24220:SF416 7 379 1.3E-136 T 22-04-2016 TOLA_RS13345 13ec7f161d5122b59b7398e96df73cf4 215 PIRSF PIRSF016482 1 215 6.8E-56 T 22-04-2016 IPR007445 Pilus assembly protein, PilO TOLA_RS13345 13ec7f161d5122b59b7398e96df73cf4 215 Gene3D G3DSA:3.30.70.60 94 210 7.2E-30 T 22-04-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TOLA_RS13345 13ec7f161d5122b59b7398e96df73cf4 215 Pfam PF04350 Pilus assembly protein, PilO 49 200 3.4E-45 T 22-04-2016 IPR007445 Pilus assembly protein, PilO TOLA_RS13345 13ec7f161d5122b59b7398e96df73cf4 215 PANTHER PTHR39555:SF1 1 214 2.5E-40 T 22-04-2016 TOLA_RS13345 13ec7f161d5122b59b7398e96df73cf4 215 PANTHER PTHR39555 1 214 2.5E-40 T 22-04-2016 TOLA_RS13345 13ec7f161d5122b59b7398e96df73cf4 215 Gene3D G3DSA:1.10.287.540 57 93 1.6E-8 T 22-04-2016 IPR023218 UPF0291 structural domain TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 Gene3D G3DSA:2.40.50.140 285 343 1.3E-12 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 SUPERFAMILY SSF50331 236 359 1.73E-27 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 Gene3D G3DSA:2.40.50.100 239 284 5.7E-9 T 22-04-2016 TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 Gene3D G3DSA:2.40.50.100 345 353 5.7E-9 T 22-04-2016 TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 Pfam PF00005 ABC transporter 20 161 6.7E-34 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 SUPERFAMILY SSF52540 4 242 4.17E-87 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 SMART SM00382 28 211 2.1E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 Pfam PF08402 TOBE domain 280 351 8.4E-9 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 PANTHER PTHR24220:SF448 5 267 9.0E-163 T 22-04-2016 TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 PANTHER PTHR24220:SF448 298 314 9.0E-163 T 22-04-2016 TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 Gene3D G3DSA:3.40.50.300 4 235 2.2E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 PANTHER PTHR24220 5 267 9.0E-163 T 22-04-2016 TOLA_RS05230 af8a2b1aef335a373da5d0f7cf5d2c4c 375 PANTHER PTHR24220 298 314 9.0E-163 T 22-04-2016 TOLA_RS10840 dbd81d96d48e4a8dbea03b3cef9989e2 74 Gene3D G3DSA:1.20.5.300 3 53 1.7E-16 T 22-04-2016 TOLA_RS10840 dbd81d96d48e4a8dbea03b3cef9989e2 74 Hamap MF_00715 Protein SlyX [slyX]. 7 74 16.803 T 22-04-2016 IPR007236 SlyX TOLA_RS10840 dbd81d96d48e4a8dbea03b3cef9989e2 74 Pfam PF04102 SlyX 8 74 1.0E-24 T 22-04-2016 IPR007236 SlyX TOLA_RS10840 dbd81d96d48e4a8dbea03b3cef9989e2 74 PANTHER PTHR36508 3 74 9.8E-24 T 22-04-2016 TOLA_RS04080 0ffc9c10159ac061947d06eaf2cdf8fa 184 Gene3D G3DSA:2.40.100.10 22 183 5.3E-49 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS04080 0ffc9c10159ac061947d06eaf2cdf8fa 184 PANTHER PTHR11071 25 181 2.0E-55 T 22-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 TOLA_RS04080 0ffc9c10159ac061947d06eaf2cdf8fa 184 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 58 75 - T 22-04-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 TOLA_RS04080 0ffc9c10159ac061947d06eaf2cdf8fa 184 SUPERFAMILY SSF50891 20 182 8.62E-51 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS04080 0ffc9c10159ac061947d06eaf2cdf8fa 184 PANTHER PTHR11071:SF192 25 181 2.0E-55 T 22-04-2016 TOLA_RS04080 0ffc9c10159ac061947d06eaf2cdf8fa 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 136 151 1.6E-11 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 TOLA_RS04080 0ffc9c10159ac061947d06eaf2cdf8fa 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 37 52 1.6E-11 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 TOLA_RS04080 0ffc9c10159ac061947d06eaf2cdf8fa 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 63 75 1.6E-11 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 TOLA_RS04080 0ffc9c10159ac061947d06eaf2cdf8fa 184 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 24 180 2.7E-44 T 22-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 TOLA_RS09315 3ceb8eb6daac78609878512f53764bd1 505 PANTHER PTHR24220 10 388 4.9E-163 T 22-04-2016 TOLA_RS09315 3ceb8eb6daac78609878512f53764bd1 505 SMART SM00382 33 222 2.7E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS09315 3ceb8eb6daac78609878512f53764bd1 505 SMART SM00382 287 482 2.2E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS09315 3ceb8eb6daac78609878512f53764bd1 505 Gene3D G3DSA:3.40.50.300 258 495 3.6E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09315 3ceb8eb6daac78609878512f53764bd1 505 Pfam PF00005 ABC transporter 24 174 5.4E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS09315 3ceb8eb6daac78609878512f53764bd1 505 Pfam PF00005 ABC transporter 279 433 1.8E-20 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS09315 3ceb8eb6daac78609878512f53764bd1 505 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS09315 3ceb8eb6daac78609878512f53764bd1 505 Gene3D G3DSA:3.40.50.300 7 231 5.5E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09315 3ceb8eb6daac78609878512f53764bd1 505 PANTHER PTHR24220:SF308 10 388 4.9E-163 T 22-04-2016 TOLA_RS09315 3ceb8eb6daac78609878512f53764bd1 505 SUPERFAMILY SSF52540 250 487 5.77E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09315 3ceb8eb6daac78609878512f53764bd1 505 SUPERFAMILY SSF52540 8 230 2.56E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05255 25c80dd37705e1986aaeaf02656dd301 321 SUPERFAMILY SSF53067 5 318 2.86E-61 T 22-04-2016 TOLA_RS05255 25c80dd37705e1986aaeaf02656dd301 321 PANTHER PTHR30514 1 320 5.0E-113 T 22-04-2016 TOLA_RS05255 25c80dd37705e1986aaeaf02656dd301 321 Hamap MF_00524 Glucokinase [glk]. 2 316 39.493 T 22-04-2016 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 TOLA_RS05255 25c80dd37705e1986aaeaf02656dd301 321 Gene3D G3DSA:3.40.367.20 100 299 1.0E-74 T 22-04-2016 TOLA_RS05255 25c80dd37705e1986aaeaf02656dd301 321 PANTHER PTHR30514:SF0 1 320 5.0E-113 T 22-04-2016 TOLA_RS05255 25c80dd37705e1986aaeaf02656dd301 321 TIGRFAM TIGR00749 glk: glucokinase 6 310 3.4E-133 T 22-04-2016 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 TOLA_RS05255 25c80dd37705e1986aaeaf02656dd301 321 Pfam PF02685 Glucokinase 6 315 1.4E-121 T 22-04-2016 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 TOLA_RS00615 d684df34a9e6f0a78072afb5f3f0a082 144 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 1.7E-43 T 22-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 TOLA_RS00615 d684df34a9e6f0a78072afb5f3f0a082 144 ProSitePatterns PS00475 Ribosomal protein L15 signature. 109 139 - T 22-04-2016 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00615 d684df34a9e6f0a78072afb5f3f0a082 144 PANTHER PTHR12934 1 144 1.3E-60 T 22-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 TOLA_RS00615 d684df34a9e6f0a78072afb5f3f0a082 144 Gene3D G3DSA:3.100.10.10 32 143 7.7E-20 T 22-04-2016 TOLA_RS00615 d684df34a9e6f0a78072afb5f3f0a082 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 1.6E-25 T 22-04-2016 IPR021131 Ribosomal protein L18e/L15P TOLA_RS00615 d684df34a9e6f0a78072afb5f3f0a082 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 144 17.599 T 22-04-2016 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 TOLA_RS00615 d684df34a9e6f0a78072afb5f3f0a082 144 SUPERFAMILY SSF52080 4 143 7.59E-42 T 22-04-2016 IPR021131 Ribosomal protein L18e/L15P TOLA_RS12435 75c366cd50b8f1ad5b0bb4607aa0da51 958 Gene3D G3DSA:3.40.50.300 524 603 3.4E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12435 75c366cd50b8f1ad5b0bb4607aa0da51 958 Gene3D G3DSA:3.40.50.300 720 860 3.4E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12435 75c366cd50b8f1ad5b0bb4607aa0da51 958 TIGRFAM TIGR03744 traC_PFL_4706: conjugative transfer ATPase, PFL_4706 family 52 947 0.0 T 22-04-2016 IPR022303 Conjugative transfer ATPase TOLA_RS12435 75c366cd50b8f1ad5b0bb4607aa0da51 958 SUPERFAMILY SSF52540 478 607 3.85E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12435 75c366cd50b8f1ad5b0bb4607aa0da51 958 SUPERFAMILY SSF52540 643 898 3.85E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12435 75c366cd50b8f1ad5b0bb4607aa0da51 958 Pfam PF11130 F pilus assembly Type-IV secretion system for plasmid transfer 63 336 9.5E-75 T 22-04-2016 IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 PRINTS PR00145 Argininosuccinate lyase family signature 135 157 1.6E-7 T 22-04-2016 TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 PRINTS PR00145 Argininosuccinate lyase family signature 177 197 1.6E-7 T 22-04-2016 TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 PRINTS PR00145 Argininosuccinate lyase family signature 319 335 1.6E-7 T 22-04-2016 TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 SUPERFAMILY SSF48557 4 461 3.14E-155 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 5 461 1.2E-220 T 22-04-2016 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 Pfam PF10415 Fumarase C C-terminus 410 462 2.9E-22 T 22-04-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 PRINTS PR00149 Fumarate lyase superfamily signature 182 200 1.5E-34 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 1.5E-34 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 1.5E-34 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 1.5E-34 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 PANTHER PTHR11444 1 464 3.3E-237 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 Gene3D G3DSA:1.10.275.10 4 140 2.1E-59 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 Gene3D G3DSA:1.10.40.30 419 465 1.6E-28 T 22-04-2016 TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 Hamap MF_00743 Fumarate hydratase class II [fumC]. 4 464 89.426 T 22-04-2016 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 Pfam PF00206 Lyase 13 344 5.0E-110 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 Gene3D G3DSA:1.20.200.10 141 418 2.9E-101 T 22-04-2016 TOLA_RS08035 6a17ddf07444afd0b92b4a4c5bf714d7 468 PANTHER PTHR11444:SF1 1 464 3.3E-237 T 22-04-2016 TOLA_RS10315 159d5b1d38f984915ef42e745187bdec 112 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 23 104 3.5E-28 T 22-04-2016 IPR003849 Preprotein translocase YajC TOLA_RS10315 159d5b1d38f984915ef42e745187bdec 112 Pfam PF02699 Preprotein translocase subunit 26 101 3.0E-24 T 22-04-2016 IPR003849 Preprotein translocase YajC TOLA_RS10315 159d5b1d38f984915ef42e745187bdec 112 PANTHER PTHR33909:SF1 1 112 9.6E-30 T 22-04-2016 TOLA_RS10315 159d5b1d38f984915ef42e745187bdec 112 SMART SM01323 20 104 1.0E-33 T 22-04-2016 IPR003849 Preprotein translocase YajC TOLA_RS10315 159d5b1d38f984915ef42e745187bdec 112 PRINTS PR01853 Bacterial YajC preprotein translocase signature 60 78 3.7E-12 T 22-04-2016 IPR003849 Preprotein translocase YajC TOLA_RS10315 159d5b1d38f984915ef42e745187bdec 112 PRINTS PR01853 Bacterial YajC preprotein translocase signature 22 42 3.7E-12 T 22-04-2016 IPR003849 Preprotein translocase YajC TOLA_RS10315 159d5b1d38f984915ef42e745187bdec 112 PANTHER PTHR33909 1 112 9.6E-30 T 22-04-2016 TOLA_RS05130 4cec83b17aac375cc9ab5165bdd716c1 327 Gene3D G3DSA:3.90.180.10 4 87 5.6E-7 T 22-04-2016 IPR011032 GroES-like TOLA_RS05130 4cec83b17aac375cc9ab5165bdd716c1 327 SUPERFAMILY SSF51735 117 293 6.15E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS05130 4cec83b17aac375cc9ab5165bdd716c1 327 Pfam PF00107 Zinc-binding dehydrogenase 159 280 3.3E-15 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TOLA_RS05130 4cec83b17aac375cc9ab5165bdd716c1 327 SMART SM00829 16 323 1.6E-5 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TOLA_RS05130 4cec83b17aac375cc9ab5165bdd716c1 327 PANTHER PTHR11695 16 327 1.2E-145 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 TOLA_RS05130 4cec83b17aac375cc9ab5165bdd716c1 327 Gene3D G3DSA:3.40.50.720 126 290 1.3E-75 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS05130 4cec83b17aac375cc9ab5165bdd716c1 327 PANTHER PTHR11695:SF13 16 327 1.2E-145 T 22-04-2016 IPR014188 Acrylyl-CoA reductase AcuI TOLA_RS05130 4cec83b17aac375cc9ab5165bdd716c1 327 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 3 325 1.8E-135 T 22-04-2016 IPR014188 Acrylyl-CoA reductase AcuI TOLA_RS05130 4cec83b17aac375cc9ab5165bdd716c1 327 SUPERFAMILY SSF50129 2 143 2.99E-43 T 22-04-2016 IPR011032 GroES-like TOLA_RS12875 76af97a9aaae5c86f1406161005beab1 148 Pfam PF00364 Biotin-requiring enzyme 74 147 3.2E-27 T 22-04-2016 IPR000089 Biotin/lipoyl attachment TOLA_RS12875 76af97a9aaae5c86f1406161005beab1 148 Gene3D G3DSA:2.40.50.100 73 148 4.5E-33 T 22-04-2016 TOLA_RS12875 76af97a9aaae5c86f1406161005beab1 148 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 148 1.1E-55 T 22-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 TOLA_RS12875 76af97a9aaae5c86f1406161005beab1 148 SUPERFAMILY SSF51230 73 148 3.27E-26 T 22-04-2016 IPR011053 Single hybrid motif TOLA_RS12875 76af97a9aaae5c86f1406161005beab1 148 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 104 121 - T 22-04-2016 IPR001882 Biotin-binding site TOLA_RS12875 76af97a9aaae5c86f1406161005beab1 148 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 109 122 2.1E-16 T 22-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 TOLA_RS12875 76af97a9aaae5c86f1406161005beab1 148 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 77 90 2.1E-16 T 22-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 TOLA_RS12875 76af97a9aaae5c86f1406161005beab1 148 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 94 108 2.1E-16 T 22-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 TOLA_RS12875 76af97a9aaae5c86f1406161005beab1 148 PANTHER PTHR23151 1 148 8.6E-49 T 22-04-2016 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 PIRSF PIRSF002560 1 155 1.1E-63 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 PANTHER PTHR30295 1 155 4.0E-82 T 22-04-2016 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 PANTHER PTHR30295:SF9 1 155 4.0E-82 T 22-04-2016 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 Pfam PF00210 Ferritin-like domain 8 144 6.7E-37 T 22-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 PRINTS PR00601 Bacterioferritin signature 129 150 1.5E-52 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 PRINTS PR00601 Bacterioferritin signature 65 85 1.5E-52 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 PRINTS PR00601 Bacterioferritin signature 3 22 1.5E-52 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 PRINTS PR00601 Bacterioferritin signature 44 64 1.5E-52 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 PRINTS PR00601 Bacterioferritin signature 107 127 1.5E-52 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 PRINTS PR00601 Bacterioferritin signature 23 43 1.5E-52 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 PRINTS PR00601 Bacterioferritin signature 86 106 1.5E-52 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 SUPERFAMILY SSF47240 1 155 2.01E-48 T 22-04-2016 IPR009078 Ferritin-like superfamily TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 Gene3D G3DSA:1.20.1260.10 1 155 6.9E-57 T 22-04-2016 IPR012347 Ferritin-related TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 2.2E-54 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15955 3bc2834432626a6d48f2db18c6317494 155 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 Pfam PF00196 Bacterial regulatory proteins, luxR family 840 893 3.8E-18 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 855 871 9.6E-11 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 871 883 9.6E-11 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 841 855 9.6E-11 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 SUPERFAMILY SSF48452 445 808 5.88E-152 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 Gene3D G3DSA:1.25.40.10 445 813 5.6E-94 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 PANTHER PTHR26402:SF567 78 100 3.5E-17 T 22-04-2016 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 PANTHER PTHR26402:SF567 815 902 3.5E-17 T 22-04-2016 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 PANTHER PTHR26402 78 100 3.5E-17 T 22-04-2016 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 PANTHER PTHR26402 815 902 3.5E-17 T 22-04-2016 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 SUPERFAMILY SSF46894 833 897 7.82E-16 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 SUPERFAMILY SSF52540 6 226 9.1E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 Pfam PF13191 AAA ATPase domain 19 157 3.4E-9 T 22-04-2016 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 Gene3D G3DSA:1.10.10.10 839 897 9.3E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 ProSitePatterns PS00622 LuxR-type HTH domain signature. 855 882 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 SMART SM00421 838 895 1.4E-19 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 Gene3D G3DSA:3.40.50.300 88 136 2.8E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00255 530ae4b815a3515c10255d3d48d00d02 906 Gene3D G3DSA:3.40.50.300 9 56 2.8E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12565 fae94232b8cc67e1929684e9f643ced1 834 SUPERFAMILY SSF53474 62 384 3.72E-27 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS12565 fae94232b8cc67e1929684e9f643ced1 834 Gene3D G3DSA:3.40.50.1820 257 382 2.2E-5 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS12565 fae94232b8cc67e1929684e9f643ced1 834 Gene3D G3DSA:3.40.50.1820 151 210 2.2E-5 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS12565 fae94232b8cc67e1929684e9f643ced1 834 Pfam PF11339 Protein of unknown function (DUF3141) 33 610 1.6E-289 T 22-04-2016 IPR024501 Protein of unknown function DUF3141 TOLA_RS00545 22632cde1e53af7f7f198537af123408 114 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 22-04-2016 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00545 22632cde1e53af7f7f198537af123408 114 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 28.315 T 22-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 TOLA_RS00545 22632cde1e53af7f7f198537af123408 114 SUPERFAMILY SSF54843 1 110 4.58E-42 T 22-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00545 22632cde1e53af7f7f198537af123408 114 Pfam PF00237 Ribosomal protein L22p/L17e 8 107 3.3E-32 T 22-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00545 22632cde1e53af7f7f198537af123408 114 PANTHER PTHR13501 1 109 4.3E-50 T 22-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 TOLA_RS00545 22632cde1e53af7f7f198537af123408 114 Gene3D G3DSA:3.90.470.10 1 111 1.6E-42 T 22-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00545 22632cde1e53af7f7f198537af123408 114 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 2.0E-46 T 22-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 TOLA_RS03485 8157dcd46474b93afa3e33924665ab2d 274 SUPERFAMILY SSF53807 1 260 6.32E-61 T 22-04-2016 TOLA_RS03485 8157dcd46474b93afa3e33924665ab2d 274 Gene3D G3DSA:3.40.50.1980 1 118 9.9E-28 T 22-04-2016 TOLA_RS03485 8157dcd46474b93afa3e33924665ab2d 274 Pfam PF01497 Periplasmic binding protein 13 249 1.1E-27 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 TOLA_RS03485 8157dcd46474b93afa3e33924665ab2d 274 Gene3D G3DSA:3.40.50.1980 122 273 2.8E-32 T 22-04-2016 TOLA_RS03485 8157dcd46474b93afa3e33924665ab2d 274 PANTHER PTHR30532 1 274 2.0E-85 T 22-04-2016 TOLA_RS03485 8157dcd46474b93afa3e33924665ab2d 274 PANTHER PTHR30532:SF4 1 274 2.0E-85 T 22-04-2016 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SUPERFAMILY SSF55781 203 385 5.56E-8 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SUPERFAMILY SSF55785 533 640 5.06E-28 T 22-04-2016 IPR000014 PAS domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 Gene3D G3DSA:3.30.450.20 537 641 3.5E-26 T 22-04-2016 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 649 814 1.4E-50 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 Gene3D G3DSA:3.30.70.270 655 819 4.1E-60 T 22-04-2016 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 Gene3D G3DSA:3.30.450.40 217 393 9.4E-12 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 Pfam PF08447 PAS fold 118 201 1.1E-8 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 Pfam PF08447 PAS fold 428 514 1.6E-16 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SMART SM00086 600 642 1.7E-4 T 22-04-2016 IPR001610 PAC motif TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SMART SM00086 166 208 0.028 T 22-04-2016 IPR001610 PAC motif TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SMART SM00086 478 520 2.9E-5 T 22-04-2016 IPR001610 PAC motif TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SMART SM00052 825 1071 4.7E-118 T 22-04-2016 IPR001633 EAL domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 533 649 1.7E-19 T 22-04-2016 IPR000014 PAS domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 436 526 4.0E-10 T 22-04-2016 IPR000014 PAS domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 105 215 5.6E-15 T 22-04-2016 IPR000014 PAS domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SMART SM00091 402 471 0.027 T 22-04-2016 IPR000014 PAS domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SMART SM00091 92 159 0.0023 T 22-04-2016 IPR000014 PAS domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SMART SM00091 528 594 1.4E-7 T 22-04-2016 IPR000014 PAS domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 Gene3D G3DSA:3.20.20.450 828 1079 9.3E-102 T 22-04-2016 IPR001633 EAL domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SUPERFAMILY SSF55785 107 215 4.35E-17 T 22-04-2016 IPR000014 PAS domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 Pfam PF13426 PAS domain 539 641 1.0E-16 T 22-04-2016 IPR000014 PAS domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SUPERFAMILY SSF141868 830 1080 4.84E-91 T 22-04-2016 IPR001633 EAL domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 Gene3D G3DSA:3.30.450.20 104 210 1.3E-15 T 22-04-2016 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SUPERFAMILY SSF55785 407 521 1.48E-19 T 22-04-2016 IPR000014 PAS domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SMART SM00267 642 815 4.4E-71 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 Pfam PF00990 Diguanylate cyclase, GGDEF domain 653 810 2.7E-52 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 Gene3D G3DSA:3.30.450.20 406 531 3.1E-22 T 22-04-2016 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 PANTHER PTHR10799:SF774 320 472 4.1E-86 T 22-04-2016 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 PANTHER PTHR10799:SF774 686 905 4.1E-86 T 22-04-2016 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 PANTHER PTHR10799:SF774 1015 1034 4.1E-86 T 22-04-2016 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 PANTHER PTHR10799 320 472 4.1E-86 T 22-04-2016 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 PANTHER PTHR10799 686 905 4.1E-86 T 22-04-2016 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 PANTHER PTHR10799 1015 1034 4.1E-86 T 22-04-2016 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 SUPERFAMILY SSF55073 658 817 1.57E-51 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 Pfam PF13185 GAF domain 241 386 1.4E-8 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS16285 d4fd5b7079cd004a729fcb260ba56753 1098 Pfam PF00563 EAL domain 831 1066 2.6E-75 T 22-04-2016 IPR001633 EAL domain TOLA_RS05015 e3e75f1a1bddc852853e3a1b2c96e5c9 293 Pfam PF00472 RF-1 domain 157 265 2.1E-38 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TOLA_RS05015 e3e75f1a1bddc852853e3a1b2c96e5c9 293 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 2 291 3.5E-147 T 22-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 TOLA_RS05015 e3e75f1a1bddc852853e3a1b2c96e5c9 293 Gene3D G3DSA:3.30.160.20 156 234 9.4E-37 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain TOLA_RS05015 e3e75f1a1bddc852853e3a1b2c96e5c9 293 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 173 189 - T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TOLA_RS05015 e3e75f1a1bddc852853e3a1b2c96e5c9 293 Pfam PF03462 PCRF domain 6 147 6.4E-45 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 TOLA_RS05015 e3e75f1a1bddc852853e3a1b2c96e5c9 293 SMART SM00937 13 123 2.5E-51 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 TOLA_RS05015 e3e75f1a1bddc852853e3a1b2c96e5c9 293 PANTHER PTHR11075:SF6 1 291 7.4E-144 T 22-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 TOLA_RS05015 e3e75f1a1bddc852853e3a1b2c96e5c9 293 Gene3D G3DSA:1.20.58.410 1 44 4.3E-6 T 22-04-2016 TOLA_RS05015 e3e75f1a1bddc852853e3a1b2c96e5c9 293 SUPERFAMILY SSF75620 2 292 6.93E-123 T 22-04-2016 TOLA_RS05015 e3e75f1a1bddc852853e3a1b2c96e5c9 293 PANTHER PTHR11075 1 291 7.4E-144 T 22-04-2016 TOLA_RS05445 361f50c909895ab3d7c9cb763a1518ab 114 Gene3D G3DSA:1.10.10.60 14 101 2.9E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS05445 361f50c909895ab3d7c9cb763a1518ab 114 Pfam PF01527 Transposase 12 88 3.2E-16 T 22-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 TOLA_RS05445 361f50c909895ab3d7c9cb763a1518ab 114 SUPERFAMILY SSF46689 12 107 7.88E-19 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS05445 361f50c909895ab3d7c9cb763a1518ab 114 PANTHER PTHR33215 8 113 5.2E-23 T 22-04-2016 TOLA_RS14020 de2be39df1c6f7bfb7ca3d1b578a76ae 545 PANTHER PTHR11550 1 545 0.0 T 22-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 TOLA_RS14020 de2be39df1c6f7bfb7ca3d1b578a76ae 545 SUPERFAMILY SSF52317 289 541 1.48E-88 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS14020 de2be39df1c6f7bfb7ca3d1b578a76ae 545 Pfam PF00117 Glutamine amidotransferase class-I 301 535 1.0E-63 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 TOLA_RS14020 de2be39df1c6f7bfb7ca3d1b578a76ae 545 TIGRFAM TIGR00337 PyrG: CTP synthase 2 535 2.4E-258 T 22-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 TOLA_RS14020 de2be39df1c6f7bfb7ca3d1b578a76ae 545 SUPERFAMILY SSF52540 3 268 1.51E-122 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14020 de2be39df1c6f7bfb7ca3d1b578a76ae 545 Gene3D G3DSA:3.40.50.880 288 541 5.2E-99 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS14020 de2be39df1c6f7bfb7ca3d1b578a76ae 545 Pfam PF06418 CTP synthase N-terminus 4 266 5.1E-126 T 22-04-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 TOLA_RS14020 de2be39df1c6f7bfb7ca3d1b578a76ae 545 Gene3D G3DSA:3.40.50.300 1 280 2.2E-134 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14020 de2be39df1c6f7bfb7ca3d1b578a76ae 545 Hamap MF_01227 CTP synthase [pyrG]. 3 540 51.189 T 22-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 TOLA_RS05170 378e9b5421b726d93a7979b881b2d323 79 PANTHER PTHR36450:SF1 2 79 1.5E-28 T 22-04-2016 TOLA_RS05170 378e9b5421b726d93a7979b881b2d323 79 TIGRFAM TIGR00412 redox_disulf_2: redox-active disulfide protein 2 1 74 1.3E-22 T 22-04-2016 IPR005243 Redox-active disulphide protein 2 TOLA_RS05170 378e9b5421b726d93a7979b881b2d323 79 PANTHER PTHR36450 2 79 1.5E-28 T 22-04-2016 TOLA_RS05170 378e9b5421b726d93a7979b881b2d323 79 SUPERFAMILY SSF52833 2 76 1.07E-20 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS05170 378e9b5421b726d93a7979b881b2d323 79 Pfam PF13192 Thioredoxin domain 3 76 9.5E-25 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS05170 378e9b5421b726d93a7979b881b2d323 79 Gene3D G3DSA:3.40.30.10 2 76 2.9E-28 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS05170 378e9b5421b726d93a7979b881b2d323 79 PIRSF PIRSF037031 1 78 6.5E-29 T 22-04-2016 IPR005243 Redox-active disulphide protein 2 TOLA_RS06385 13d4663017b71720cafb03cf2c109cf1 184 SUPERFAMILY SSF143456 2 184 1.96E-63 T 22-04-2016 TOLA_RS06385 13d4663017b71720cafb03cf2c109cf1 184 Gene3D G3DSA:3.40.1740.10 2 41 1.4E-34 T 22-04-2016 TOLA_RS06385 13d4663017b71720cafb03cf2c109cf1 184 Gene3D G3DSA:3.40.1740.10 128 175 1.4E-34 T 22-04-2016 TOLA_RS06385 13d4663017b71720cafb03cf2c109cf1 184 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 2 184 37.286 T 22-04-2016 IPR003774 Protein of unknown function UPF0301 TOLA_RS06385 13d4663017b71720cafb03cf2c109cf1 184 Pfam PF02622 Uncharacterized ACR, COG1678 13 171 6.1E-48 T 22-04-2016 IPR003774 Protein of unknown function UPF0301 TOLA_RS06385 13d4663017b71720cafb03cf2c109cf1 184 PANTHER PTHR30327 1 184 2.6E-62 T 22-04-2016 TOLA_RS06385 13d4663017b71720cafb03cf2c109cf1 184 PANTHER PTHR30327:SF1 1 184 2.6E-62 T 22-04-2016 TOLA_RS06385 13d4663017b71720cafb03cf2c109cf1 184 Gene3D G3DSA:3.30.70.1300 45 127 2.9E-25 T 22-04-2016 TOLA_RS11100 3947d04f9f9988f19914daba20faf52f 319 Gene3D G3DSA:1.20.272.10 205 315 9.1E-18 T 22-04-2016 TOLA_RS11100 3947d04f9f9988f19914daba20faf52f 319 Pfam PF13177 DNA polymerase III, delta subunit 12 163 7.4E-46 T 22-04-2016 TOLA_RS11100 3947d04f9f9988f19914daba20faf52f 319 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 11 195 8.6E-59 T 22-04-2016 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS11100 3947d04f9f9988f19914daba20faf52f 319 PANTHER PTHR11669:SF8 11 256 5.3E-61 T 22-04-2016 TOLA_RS11100 3947d04f9f9988f19914daba20faf52f 319 SUPERFAMILY SSF48019 206 315 6.12E-6 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 TOLA_RS11100 3947d04f9f9988f19914daba20faf52f 319 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 206 315 5.6E-19 T 22-04-2016 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS11100 3947d04f9f9988f19914daba20faf52f 319 PANTHER PTHR11669 11 256 5.3E-61 T 22-04-2016 TOLA_RS11100 3947d04f9f9988f19914daba20faf52f 319 Gene3D G3DSA:3.40.50.300 10 162 3.3E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11100 3947d04f9f9988f19914daba20faf52f 319 SUPERFAMILY SSF52540 16 189 4.62E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04115 3ea08ed468a67e755adfd9e26cf97e14 351 PANTHER PTHR11076:SF32 1 346 3.0E-161 T 22-04-2016 TOLA_RS04115 3ea08ed468a67e755adfd9e26cf97e14 351 Gene3D G3DSA:3.30.1490.100 238 349 6.5E-34 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS04115 3ea08ed468a67e755adfd9e26cf97e14 351 SUPERFAMILY SSF56672 1 233 3.65E-89 T 22-04-2016 TOLA_RS04115 3ea08ed468a67e755adfd9e26cf97e14 351 Pfam PF11799 impB/mucB/samB family C-terminal domain 235 335 1.4E-7 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS04115 3ea08ed468a67e755adfd9e26cf97e14 351 SUPERFAMILY SSF100879 241 349 2.35E-22 T 22-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS04115 3ea08ed468a67e755adfd9e26cf97e14 351 Hamap MF_01113 DNA polymerase IV [dinB]. 1 348 35.845 T 22-04-2016 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS04115 3ea08ed468a67e755adfd9e26cf97e14 351 PANTHER PTHR11076 1 346 3.0E-161 T 22-04-2016 TOLA_RS04115 3ea08ed468a67e755adfd9e26cf97e14 351 Pfam PF00817 impB/mucB/samB family 7 154 2.4E-50 T 22-04-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS04115 3ea08ed468a67e755adfd9e26cf97e14 351 Gene3D G3DSA:3.30.70.270 66 163 2.4E-34 T 22-04-2016 TOLA_RS04115 3ea08ed468a67e755adfd9e26cf97e14 351 Pfam PF11798 IMS family HHH motif 166 197 1.7E-6 T 22-04-2016 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS04115 3ea08ed468a67e755adfd9e26cf97e14 351 Gene3D G3DSA:1.10.150.20 166 235 4.0E-21 T 22-04-2016 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 Pfam PF00989 PAS fold 214 303 1.9E-5 T 22-04-2016 IPR013767 PAS fold GO:0006355 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 Gene3D G3DSA:3.30.450.20 36 170 8.1E-43 T 22-04-2016 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 PANTHER PTHR24423:SF375 53 159 2.8E-139 T 22-04-2016 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 PANTHER PTHR24423:SF375 192 533 2.8E-139 T 22-04-2016 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 PANTHER PTHR24423 192 533 2.8E-139 T 22-04-2016 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 Gene3D G3DSA:3.30.450.20 217 313 2.5E-7 T 22-04-2016 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 Gene3D G3DSA:1.10.287.130 314 377 2.5E-21 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 SUPERFAMILY SSF55890 327 394 2.35E-12 T 22-04-2016 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 324 369 8.4E-11 T 22-04-2016 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 Gene3D G3DSA:3.30.565.10 405 532 2.1E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 PANTHER PTHR24423 53 159 2.8E-139 T 22-04-2016 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 SUPERFAMILY SSF103190 43 169 5.49E-35 T 22-04-2016 IPR029151 Periplasmic sensor domain-like TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 489 1.3E-8 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 475 1.3E-8 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 528 1.3E-8 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 508 1.3E-8 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 Pfam PF17203 Single cache domain 3 43 170 3.5E-22 T 22-04-2016 IPR033463 Single cache domain 3 TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 SMART SM00387 422 531 2.2E-24 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 426 529 2.7E-18 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS12980 cc27c38d6107675e2531c1d30aa5615d 536 SUPERFAMILY SSF55874 398 528 1.22E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 Gene3D G3DSA:1.20.1080.10 3 255 2.2E-80 T 22-04-2016 IPR023271 Aquaporin-like TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 PANTHER PTHR19139:SF100 8 258 1.6E-78 T 22-04-2016 TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 SUPERFAMILY SSF81338 6 254 3.53E-73 T 22-04-2016 IPR023271 Aquaporin-like TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 PRINTS PR00783 Major intrinsic protein family signature 182 204 1.4E-48 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 PRINTS PR00783 Major intrinsic protein family signature 149 167 1.4E-48 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 PRINTS PR00783 Major intrinsic protein family signature 83 102 1.4E-48 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 PRINTS PR00783 Major intrinsic protein family signature 232 252 1.4E-48 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 PRINTS PR00783 Major intrinsic protein family signature 46 70 1.4E-48 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 PRINTS PR00783 Major intrinsic protein family signature 7 26 1.4E-48 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 ProSitePatterns PS00221 MIP family signature. 64 72 - T 22-04-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 PANTHER PTHR19139 8 258 1.6E-78 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 TIGRFAM TIGR00861 MIP: MIP family channel proteins 11 249 5.6E-64 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS08560 829d59cb44d4a2aa6d49cda30dc97a8d 277 Pfam PF00230 Major intrinsic protein 6 249 1.1E-63 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS11055 afe6e23e4dbe37b0dadf76c730a897a8 240 PANTHER PTHR23026 3 185 4.6E-72 T 22-04-2016 TOLA_RS11055 afe6e23e4dbe37b0dadf76c730a897a8 240 Pfam PF00881 Nitroreductase family 8 159 6.4E-21 T 22-04-2016 IPR029479 Nitroreductase TOLA_RS11055 afe6e23e4dbe37b0dadf76c730a897a8 240 SUPERFAMILY SSF55469 3 239 9.95E-74 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 TOLA_RS11055 afe6e23e4dbe37b0dadf76c730a897a8 240 PIRSF PIRSF005426 1 240 2.2E-86 T 22-04-2016 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 TOLA_RS11055 afe6e23e4dbe37b0dadf76c730a897a8 240 PANTHER PTHR23026:SF98 3 185 4.6E-72 T 22-04-2016 TOLA_RS11055 afe6e23e4dbe37b0dadf76c730a897a8 240 Gene3D G3DSA:3.40.109.10 3 239 3.1E-76 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 PANTHER PTHR22642 24 296 9.1E-263 T 22-04-2016 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 PANTHER PTHR22642 320 501 9.1E-263 T 22-04-2016 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 Hamap MF_01953 Urease subunit alpha [ureC]. 2 567 57.154 T 22-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 PANTHER PTHR22642:SF7 24 296 9.1E-263 T 22-04-2016 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 PANTHER PTHR22642:SF7 320 501 9.1E-263 T 22-04-2016 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 Pfam PF01979 Amidohydrolase family 125 454 5.8E-83 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 ProSitePatterns PS01120 Urease nickel ligands signature. 127 140 - T 22-04-2016 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 Gene3D G3DSA:2.30.40.10 68 143 1.3E-14 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 ProSitePatterns PS00145 Urease active site. 317 333 - T 22-04-2016 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 119 2.0E-56 T 22-04-2016 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 427 440 5.6E-35 T 22-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 401 416 5.6E-35 T 22-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 334 350 5.6E-35 T 22-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 295 312 5.6E-35 T 22-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 SUPERFAMILY SSF51338 422 477 1.62E-6 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 SUPERFAMILY SSF51338 3 177 6.38E-65 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 Gene3D G3DSA:3.20.20.140 144 429 3.4E-208 T 22-04-2016 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 Gene3D G3DSA:3.20.20.140 488 565 3.4E-208 T 22-04-2016 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 567 6.9E-294 T 22-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 SUPERFAMILY SSF51556 481 567 2.28E-199 T 22-04-2016 IPR032466 Metal-dependent hydrolase TOLA_RS08245 4cc4e8533faa9ad5b5f5e1c6514ddbf9 567 SUPERFAMILY SSF51556 129 432 2.28E-199 T 22-04-2016 IPR032466 Metal-dependent hydrolase TOLA_RS15940 8fd0e37de0253f2af4dc771fb642dfdc 465 Pfam PF02378 Phosphotransferase system, EIIC 110 384 2.7E-25 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS15940 8fd0e37de0253f2af4dc771fb642dfdc 465 PANTHER PTHR30175 1 462 9.6E-153 T 22-04-2016 TOLA_RS15940 8fd0e37de0253f2af4dc771fb642dfdc 465 PANTHER PTHR30175:SF1 1 462 9.6E-153 T 22-04-2016 TOLA_RS15940 8fd0e37de0253f2af4dc771fb642dfdc 465 Gene3D G3DSA:3.30.1360.60 2 80 2.3E-26 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS15940 8fd0e37de0253f2af4dc771fb642dfdc 465 Pfam PF00367 phosphotransferase system, EIIB 8 37 3.2E-12 T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS15940 8fd0e37de0253f2af4dc771fb642dfdc 465 SUPERFAMILY SSF55604 6 80 1.7E-20 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS15940 8fd0e37de0253f2af4dc771fb642dfdc 465 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS05400 de6adbd2ff6fc1f11fafa8a61b7101aa 822 PANTHER PTHR11468:SF3 1 821 0.0 T 22-04-2016 TOLA_RS05400 de6adbd2ff6fc1f11fafa8a61b7101aa 822 PIRSF PIRSF000460 1 822 1.9E-223 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 TOLA_RS05400 de6adbd2ff6fc1f11fafa8a61b7101aa 822 Gene3D G3DSA:3.40.50.2000 486 801 2.8E-129 T 22-04-2016 TOLA_RS05400 de6adbd2ff6fc1f11fafa8a61b7101aa 822 Gene3D G3DSA:3.40.50.2000 11 485 1.4E-204 T 22-04-2016 TOLA_RS05400 de6adbd2ff6fc1f11fafa8a61b7101aa 822 PANTHER PTHR11468 1 821 0.0 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 TOLA_RS05400 de6adbd2ff6fc1f11fafa8a61b7101aa 822 Pfam PF00343 Carbohydrate phosphorylase 102 816 0.0 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 TOLA_RS05400 de6adbd2ff6fc1f11fafa8a61b7101aa 822 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 660 672 - T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 TOLA_RS05400 de6adbd2ff6fc1f11fafa8a61b7101aa 822 SUPERFAMILY SSF53756 10 820 0.0 T 22-04-2016 TOLA_RS05400 de6adbd2ff6fc1f11fafa8a61b7101aa 822 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 13 816 0.0 T 22-04-2016 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 TOLA_RS12040 055589757cb8f22c22ea05270ad67457 436 SUPERFAMILY SSF54534 178 279 8.5E-23 T 22-04-2016 TOLA_RS12040 055589757cb8f22c22ea05270ad67457 436 Gene3D G3DSA:3.10.50.40 289 408 5.2E-33 T 22-04-2016 TOLA_RS12040 055589757cb8f22c22ea05270ad67457 436 Gene3D G3DSA:3.10.50.40 171 288 1.1E-25 T 22-04-2016 TOLA_RS12040 055589757cb8f22c22ea05270ad67457 436 Pfam PF00639 PPIC-type PPIASE domain 293 385 9.7E-24 T 22-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 TOLA_RS12040 055589757cb8f22c22ea05270ad67457 436 Pfam PF00639 PPIC-type PPIASE domain 183 277 8.4E-18 T 22-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 TOLA_RS12040 055589757cb8f22c22ea05270ad67457 436 PANTHER PTHR10657 11 428 6.6E-101 T 22-04-2016 TOLA_RS12040 055589757cb8f22c22ea05270ad67457 436 PANTHER PTHR10657:SF15 11 428 6.6E-101 T 22-04-2016 TOLA_RS12040 055589757cb8f22c22ea05270ad67457 436 Pfam PF09312 SurA N-terminal domain 30 147 4.2E-36 T 22-04-2016 IPR015391 SurA N-terminal TOLA_RS12040 055589757cb8f22c22ea05270ad67457 436 SUPERFAMILY SSF54534 288 389 3.99E-30 T 22-04-2016 TOLA_RS12040 055589757cb8f22c22ea05270ad67457 436 SUPERFAMILY SSF109998 30 207 8.93E-37 T 22-04-2016 IPR027304 Trigger factor/SurA domain TOLA_RS12040 055589757cb8f22c22ea05270ad67457 436 Hamap MF_01183 Chaperone SurA [surA]. 15 432 30.853 T 22-04-2016 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 TOLA_RS12040 055589757cb8f22c22ea05270ad67457 436 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 325 346 - T 22-04-2016 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site TOLA_RS02910 435c46914036ae5ea0b6363a37f5f432 286 SUPERFAMILY SSF56752 4 280 6.41E-76 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 TOLA_RS02910 435c46914036ae5ea0b6363a37f5f432 286 ProSitePatterns PS00770 Aminotransferases class-IV signature. 181 211 - T 22-04-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 TOLA_RS02910 435c46914036ae5ea0b6363a37f5f432 286 PANTHER PTHR11825:SF38 4 285 1.4E-100 T 22-04-2016 TOLA_RS02910 435c46914036ae5ea0b6363a37f5f432 286 Pfam PF01063 Amino-transferase class IV 32 256 3.1E-46 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 TOLA_RS02910 435c46914036ae5ea0b6363a37f5f432 286 Gene3D G3DSA:3.30.470.10 4 119 5.9E-33 T 22-04-2016 TOLA_RS02910 435c46914036ae5ea0b6363a37f5f432 286 Gene3D G3DSA:3.20.10.10 127 281 3.9E-46 T 22-04-2016 TOLA_RS02910 435c46914036ae5ea0b6363a37f5f432 286 PANTHER PTHR11825 4 285 1.4E-100 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 TOLA_RS02930 16c5c3bb1189cf5b8f4f27e6189e6574 69 PRINTS PR00050 Cold shock protein signature 27 36 3.2E-18 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOLA_RS02930 16c5c3bb1189cf5b8f4f27e6189e6574 69 PRINTS PR00050 Cold shock protein signature 6 21 3.2E-18 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOLA_RS02930 16c5c3bb1189cf5b8f4f27e6189e6574 69 PRINTS PR00050 Cold shock protein signature 42 60 3.2E-18 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOLA_RS02930 16c5c3bb1189cf5b8f4f27e6189e6574 69 PIRSF PIRSF002599 1 69 8.0E-24 T 22-04-2016 IPR012156 Cold shock, CspA GO:0003676 TOLA_RS02930 16c5c3bb1189cf5b8f4f27e6189e6574 69 PANTHER PTHR11544 1 68 5.3E-38 T 22-04-2016 TOLA_RS02930 16c5c3bb1189cf5b8f4f27e6189e6574 69 Gene3D G3DSA:2.40.50.140 4 68 4.9E-30 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS02930 16c5c3bb1189cf5b8f4f27e6189e6574 69 SUPERFAMILY SSF50249 3 68 1.65E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS02930 16c5c3bb1189cf5b8f4f27e6189e6574 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 36 - T 22-04-2016 IPR019844 Cold-shock conserved site TOLA_RS02930 16c5c3bb1189cf5b8f4f27e6189e6574 69 Pfam PF00313 'Cold-shock' DNA-binding domain 5 68 1.6E-29 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOLA_RS02930 16c5c3bb1189cf5b8f4f27e6189e6574 69 SMART SM00357 5 69 1.1E-28 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 TOLA_RS08865 a6ee7160a4a54c1a99eee228066cffdd 159 Gene3D G3DSA:1.10.10.10 3 137 2.5E-39 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08865 a6ee7160a4a54c1a99eee228066cffdd 159 PANTHER PTHR33164 1 137 2.1E-30 T 22-04-2016 TOLA_RS08865 a6ee7160a4a54c1a99eee228066cffdd 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 2.8E-19 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS08865 a6ee7160a4a54c1a99eee228066cffdd 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 2.8E-19 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS08865 a6ee7160a4a54c1a99eee228066cffdd 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 2.8E-19 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS08865 a6ee7160a4a54c1a99eee228066cffdd 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 2.8E-19 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS08865 a6ee7160a4a54c1a99eee228066cffdd 159 SMART SM00347 25 125 7.5E-28 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS08865 a6ee7160a4a54c1a99eee228066cffdd 159 Pfam PF01047 MarR family 32 89 5.3E-17 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS08865 a6ee7160a4a54c1a99eee228066cffdd 159 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 22-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site TOLA_RS08865 a6ee7160a4a54c1a99eee228066cffdd 159 SUPERFAMILY SSF46785 4 138 5.46E-34 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10980 9e36bcf002e7c53eb1bffb52095380cd 499 PANTHER PTHR38464 2 499 2.4E-215 T 22-04-2016 TOLA_RS10980 9e36bcf002e7c53eb1bffb52095380cd 499 Pfam PF11762 L-arabinose isomerase C-terminal domain 362 475 2.0E-46 T 22-04-2016 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4|UniPathway: UPA00145 TOLA_RS10980 9e36bcf002e7c53eb1bffb52095380cd 499 Pfam PF02610 L-arabinose isomerase 5 359 3.0E-175 T 22-04-2016 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4|UniPathway: UPA00145 TOLA_RS10980 9e36bcf002e7c53eb1bffb52095380cd 499 PANTHER PTHR38464:SF1 2 499 2.4E-215 T 22-04-2016 TOLA_RS10980 9e36bcf002e7c53eb1bffb52095380cd 499 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 1 304 7.0E-122 T 22-04-2016 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4|UniPathway: UPA00145 TOLA_RS10980 9e36bcf002e7c53eb1bffb52095380cd 499 PIRSF PIRSF001478 1 499 3.2E-245 T 22-04-2016 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4|UniPathway: UPA00145 TOLA_RS10980 9e36bcf002e7c53eb1bffb52095380cd 499 SUPERFAMILY SSF53743 1 327 3.14E-124 T 22-04-2016 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 TOLA_RS10980 9e36bcf002e7c53eb1bffb52095380cd 499 Hamap MF_00519 L-arabinose isomerase [araA]. 1 476 64.371 T 22-04-2016 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4|UniPathway: UPA00145 TOLA_RS10980 9e36bcf002e7c53eb1bffb52095380cd 499 SUPERFAMILY SSF50443 329 497 1.18E-68 T 22-04-2016 IPR004216 L-fucose/L-arabinose isomerase, C-terminal TOLA_RS00105 c4a2331c296ec395bd47845a39104282 240 PANTHER PTHR26402:SF528 5 236 3.7E-109 T 22-04-2016 TOLA_RS00105 c4a2331c296ec395bd47845a39104282 240 Gene3D G3DSA:3.40.50.2300 4 131 9.8E-45 T 22-04-2016 TOLA_RS00105 c4a2331c296ec395bd47845a39104282 240 Pfam PF00072 Response regulator receiver domain 7 116 2.9E-33 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS00105 c4a2331c296ec395bd47845a39104282 240 SMART SM00862 156 232 1.7E-19 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS00105 c4a2331c296ec395bd47845a39104282 240 Gene3D G3DSA:1.10.10.10 135 236 1.5E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00105 c4a2331c296ec395bd47845a39104282 240 SUPERFAMILY SSF46894 137 234 4.82E-24 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TOLA_RS00105 c4a2331c296ec395bd47845a39104282 240 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 232 2.6E-20 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS00105 c4a2331c296ec395bd47845a39104282 240 SMART SM00448 5 115 9.2E-47 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS00105 c4a2331c296ec395bd47845a39104282 240 PANTHER PTHR26402 5 236 3.7E-109 T 22-04-2016 TOLA_RS00105 c4a2331c296ec395bd47845a39104282 240 SUPERFAMILY SSF52172 3 130 8.68E-45 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 468 601 1.0E-12 T 22-04-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 SUPERFAMILY SSF53633 12 299 1.48E-59 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 PIRSF PIRSF000727 12 812 2.9E-245 T 22-04-2016 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+1.1.1.3+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+1.1.1.3+2.7.2.4|KEGG: 00300+1.1.1.3+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00050|UniPathway: UPA00051|UniPathway: UPA00051 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 PANTHER PTHR21499 389 812 1.7E-154 T 22-04-2016 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 Gene3D G3DSA:3.40.1160.10 114 292 1.6E-50 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 Gene3D G3DSA:3.40.1160.10 12 59 1.6E-50 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 PANTHER PTHR21499:SF29 389 812 1.7E-154 T 22-04-2016 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 SUPERFAMILY SSF55347 609 792 2.81E-46 T 22-04-2016 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 14 456 1.7E-65 T 22-04-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 Gene3D G3DSA:3.30.360.10 631 787 1.8E-52 T 22-04-2016 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 655 677 - T 22-04-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 ProSitePatterns PS00324 Aspartokinase signature. 14 22 - T 22-04-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 Pfam PF00696 Amino acid kinase family 12 286 4.4E-45 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 SUPERFAMILY SSF51735 459 631 1.8E-23 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 Gene3D G3DSA:3.40.50.720 459 630 3.5E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00670 c282545ea9c6bc884040adc3edbaee85 812 Pfam PF00742 Homoserine dehydrogenase 610 804 1.8E-46 T 22-04-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS04835 6955d93828cb978ea8ea173d4c780042 336 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 6 330 3.0E-122 T 22-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 TOLA_RS04835 6955d93828cb978ea8ea173d4c780042 336 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 332 38.335 T 22-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 TOLA_RS04835 6955d93828cb978ea8ea173d4c780042 336 Gene3D G3DSA:3.40.1030.10 71 334 2.2E-103 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 TOLA_RS04835 6955d93828cb978ea8ea173d4c780042 336 PANTHER PTHR11922:SF5 60 336 4.5E-112 T 22-04-2016 TOLA_RS04835 6955d93828cb978ea8ea173d4c780042 336 Gene3D G3DSA:1.20.970.10 5 68 9.6E-21 T 22-04-2016 TOLA_RS04835 6955d93828cb978ea8ea173d4c780042 336 SUPERFAMILY SSF52418 70 330 1.44E-91 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 TOLA_RS04835 6955d93828cb978ea8ea173d4c780042 336 Pfam PF00591 Glycosyl transferase family, a/b domain 73 323 7.7E-96 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 TOLA_RS04835 6955d93828cb978ea8ea173d4c780042 336 PANTHER PTHR11922 60 336 4.5E-112 T 22-04-2016 TOLA_RS04835 6955d93828cb978ea8ea173d4c780042 336 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 63 2.0E-11 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain TOLA_RS04835 6955d93828cb978ea8ea173d4c780042 336 SUPERFAMILY SSF47648 5 68 1.22E-14 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain TOLA_RS14990 cd59677ebf4d135f8b0c1d59dac930ac 142 SUPERFAMILY SSF52161 1 140 5.23E-60 T 22-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 TOLA_RS14990 cd59677ebf4d135f8b0c1d59dac930ac 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 22-04-2016 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 TOLA_RS14990 cd59677ebf4d135f8b0c1d59dac930ac 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 8.0E-65 T 22-04-2016 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 TOLA_RS14990 cd59677ebf4d135f8b0c1d59dac930ac 142 Gene3D G3DSA:3.90.1180.10 3 141 1.5E-64 T 22-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 TOLA_RS14990 cd59677ebf4d135f8b0c1d59dac930ac 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.544 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TOLA_RS14990 cd59677ebf4d135f8b0c1d59dac930ac 142 PANTHER PTHR11545 1 142 4.1E-79 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TOLA_RS14990 cd59677ebf4d135f8b0c1d59dac930ac 142 Pfam PF00572 Ribosomal protein L13 15 138 6.7E-56 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TOLA_RS14990 cd59677ebf4d135f8b0c1d59dac930ac 142 PIRSF PIRSF002181 1 142 2.5E-51 T 22-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TOLA_RS13080 9bb242e85e2a1e9a82d720a8e5cfb11c 451 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 8.8E-16 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS13080 9bb242e85e2a1e9a82d720a8e5cfb11c 451 SMART SM00345 9 68 5.4E-17 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS13080 9bb242e85e2a1e9a82d720a8e5cfb11c 451 PANTHER PTHR11751 139 420 1.0E-47 T 22-04-2016 TOLA_RS13080 9bb242e85e2a1e9a82d720a8e5cfb11c 451 SUPERFAMILY SSF46785 3 72 6.64E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13080 9bb242e85e2a1e9a82d720a8e5cfb11c 451 Gene3D G3DSA:3.40.640.10 115 333 4.4E-48 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS13080 9bb242e85e2a1e9a82d720a8e5cfb11c 451 Gene3D G3DSA:1.10.10.10 3 71 1.6E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13080 9bb242e85e2a1e9a82d720a8e5cfb11c 451 SUPERFAMILY SSF53383 101 442 1.45E-68 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS13080 9bb242e85e2a1e9a82d720a8e5cfb11c 451 Pfam PF00155 Aminotransferase class I and II 110 422 4.8E-31 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TOLA_RS11345 f9969666fbe88377db76dcf2315ab332 589 PANTHER PTHR24221:SF188 12 585 0.0 T 22-04-2016 TOLA_RS11345 f9969666fbe88377db76dcf2315ab332 589 PANTHER PTHR24221 12 585 0.0 T 22-04-2016 TOLA_RS11345 f9969666fbe88377db76dcf2315ab332 589 SUPERFAMILY SSF52540 335 583 9.15E-97 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11345 f9969666fbe88377db76dcf2315ab332 589 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 18 584 1.8E-239 T 22-04-2016 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 TOLA_RS11345 f9969666fbe88377db76dcf2315ab332 589 Gene3D G3DSA:1.20.1560.10 18 333 5.1E-72 T 22-04-2016 TOLA_RS11345 f9969666fbe88377db76dcf2315ab332 589 Pfam PF00005 ABC transporter 363 513 1.9E-35 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS11345 f9969666fbe88377db76dcf2315ab332 589 SMART SM00382 372 565 2.8E-17 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS11345 f9969666fbe88377db76dcf2315ab332 589 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS11345 f9969666fbe88377db76dcf2315ab332 589 Gene3D G3DSA:3.40.50.300 345 574 8.8E-89 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11345 f9969666fbe88377db76dcf2315ab332 589 Pfam PF00664 ABC transporter transmembrane region 43 299 2.4E-55 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS11345 f9969666fbe88377db76dcf2315ab332 589 SUPERFAMILY SSF90123 18 331 1.7E-75 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS06505 6b54a2b0ee86327024aeb29101a58f6c 163 Pfam PF00293 NUDIX domain 31 146 7.1E-15 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TOLA_RS06505 6b54a2b0ee86327024aeb29101a58f6c 163 PANTHER PTHR22769 5 160 1.5E-55 T 22-04-2016 TOLA_RS06505 6b54a2b0ee86327024aeb29101a58f6c 163 SUPERFAMILY SSF55811 4 160 2.57E-34 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS06505 6b54a2b0ee86327024aeb29101a58f6c 163 PIRSF PIRSF017340 1 163 3.4E-54 T 22-04-2016 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 TOLA_RS06505 6b54a2b0ee86327024aeb29101a58f6c 163 PANTHER PTHR22769:SF25 5 160 1.5E-55 T 22-04-2016 TOLA_RS06505 6b54a2b0ee86327024aeb29101a58f6c 163 Gene3D G3DSA:3.90.79.10 2 161 5.8E-56 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS13825 5a359a18cf93d9756c03712122db46ea 379 PANTHER PTHR30365 1 379 2.6E-186 T 22-04-2016 TOLA_RS13825 5a359a18cf93d9756c03712122db46ea 379 PANTHER PTHR30365:SF6 1 379 2.6E-186 T 22-04-2016 TOLA_RS13825 5a359a18cf93d9756c03712122db46ea 379 PIRSF PIRSF000267 2 378 8.5E-128 T 22-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 TOLA_RS13825 5a359a18cf93d9756c03712122db46ea 379 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 1 379 5.5E-173 T 22-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 TOLA_RS13825 5a359a18cf93d9756c03712122db46ea 379 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 361 2.8E-112 T 22-04-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 TOLA_RS14710 fcb90d8d4e879d0f4b0a9b3d880bb565 96 SUPERFAMILY SSF143011 6 89 2.55E-7 T 22-04-2016 TOLA_RS14710 fcb90d8d4e879d0f4b0a9b3d880bb565 96 Pfam PF15781 ParE-like toxin of type II bacterial toxin-antitoxin system 7 93 1.8E-37 T 22-04-2016 IPR031552 Type II bacterial toxin-antitoxin system, ParE-like toxin TOLA_RS12785 fd2868e6e1fba9e4be741ceb2b7bb665 325 Gene3D G3DSA:1.10.3720.10 90 312 1.5E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS12785 fd2868e6e1fba9e4be741ceb2b7bb665 325 PANTHER PTHR30465 1 320 2.2E-180 T 22-04-2016 TOLA_RS12785 fd2868e6e1fba9e4be741ceb2b7bb665 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 319 6.7E-39 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS12785 fd2868e6e1fba9e4be741ceb2b7bb665 325 SUPERFAMILY SSF161098 90 302 7.85E-17 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS12785 fd2868e6e1fba9e4be741ceb2b7bb665 325 PANTHER PTHR30465:SF47 1 320 2.2E-180 T 22-04-2016 TOLA_RS15080 07e5f4c0f63d04eb71dfbbf944ad485a 148 PANTHER PTHR30505:SF6 1 143 1.4E-64 T 22-04-2016 TOLA_RS15080 07e5f4c0f63d04eb71dfbbf944ad485a 148 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 51 67 - T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15080 07e5f4c0f63d04eb71dfbbf944ad485a 148 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 144 1.9E-30 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15080 07e5f4c0f63d04eb71dfbbf944ad485a 148 PANTHER PTHR30505 1 143 1.4E-64 T 22-04-2016 TOLA_RS15080 07e5f4c0f63d04eb71dfbbf944ad485a 148 SUPERFAMILY SSF55804 1 145 1.11E-35 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 TOLA_RS15080 07e5f4c0f63d04eb71dfbbf944ad485a 148 Gene3D G3DSA:3.40.930.10 1 145 1.6E-40 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15080 07e5f4c0f63d04eb71dfbbf944ad485a 148 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 3 144 5.3E-48 T 22-04-2016 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS14940 71ff4c27642be45adf2d5edfc39935f7 143 SUPERFAMILY SSF46785 6 135 2.82E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14940 71ff4c27642be45adf2d5edfc39935f7 143 Pfam PF01475 Ferric uptake regulator family 15 129 2.3E-11 T 22-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TOLA_RS14940 71ff4c27642be45adf2d5edfc39935f7 143 Gene3D G3DSA:1.10.10.10 7 71 1.3E-10 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14940 71ff4c27642be45adf2d5edfc39935f7 143 PANTHER PTHR33202:SF6 1 142 3.7E-35 T 22-04-2016 TOLA_RS14940 71ff4c27642be45adf2d5edfc39935f7 143 PANTHER PTHR33202 1 142 3.7E-35 T 22-04-2016 TOLA_RS11335 f9454c4226a84235794e183884f19d4b 62 SUPERFAMILY SSF158997 1 57 1.57E-20 T 22-04-2016 TOLA_RS11335 f9454c4226a84235794e183884f19d4b 62 PANTHER PTHR33505 1 59 1.0E-22 T 22-04-2016 TOLA_RS11335 f9454c4226a84235794e183884f19d4b 62 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 3 56 27.165 T 22-04-2016 IPR005651 Uncharacterised protein family UPF0434/Trm112 TOLA_RS11335 f9454c4226a84235794e183884f19d4b 62 Gene3D G3DSA:2.20.25.10 10 59 1.9E-24 T 22-04-2016 TOLA_RS11335 f9454c4226a84235794e183884f19d4b 62 Pfam PF03966 Trm112p-like protein 4 42 4.5E-11 T 22-04-2016 IPR005651 Uncharacterised protein family UPF0434/Trm112 TOLA_RS08760 902d9d43a6129b36bccdf51b34467b3d 533 PANTHER PTHR40940:SF1 1 524 8.8E-21 T 22-04-2016 TOLA_RS08760 902d9d43a6129b36bccdf51b34467b3d 533 PANTHER PTHR40940 1 524 8.8E-21 T 22-04-2016 TOLA_RS08760 902d9d43a6129b36bccdf51b34467b3d 533 Pfam PF13584 Oxygen tolerance 17 433 4.9E-51 T 22-04-2016 IPR025738 Aerotolerance-related protein BatD TOLA_RS04260 180d11c308da8fd4c9254eca5a28eb80 581 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 5 538 1.5E-139 T 22-04-2016 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 TOLA_RS04260 180d11c308da8fd4c9254eca5a28eb80 581 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS04260 180d11c308da8fd4c9254eca5a28eb80 581 SUPERFAMILY SSF90123 6 324 1.31E-38 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS04260 180d11c308da8fd4c9254eca5a28eb80 581 SUPERFAMILY SSF52540 334 576 1.5E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04260 180d11c308da8fd4c9254eca5a28eb80 581 SMART SM00382 366 568 2.2E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS04260 180d11c308da8fd4c9254eca5a28eb80 581 Gene3D G3DSA:1.20.1560.10 8 324 1.8E-27 T 22-04-2016 TOLA_RS04260 180d11c308da8fd4c9254eca5a28eb80 581 Pfam PF00005 ABC transporter 358 507 7.0E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS04260 180d11c308da8fd4c9254eca5a28eb80 581 Pfam PF00664 ABC transporter transmembrane region 24 290 5.4E-10 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS04260 180d11c308da8fd4c9254eca5a28eb80 581 Gene3D G3DSA:3.40.50.300 340 570 3.9E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04260 180d11c308da8fd4c9254eca5a28eb80 581 PANTHER PTHR24222 1 579 2.7E-209 T 22-04-2016 TOLA_RS04260 180d11c308da8fd4c9254eca5a28eb80 581 PANTHER PTHR24222:SF30 1 579 2.7E-209 T 22-04-2016 TOLA_RS08455 99b7d004a3b5ff788a2089382bb819e9 351 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 13 347 32.666 T 22-04-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 TOLA_RS08455 99b7d004a3b5ff788a2089382bb819e9 351 SUPERFAMILY SSF52733 6 342 7.46E-110 T 22-04-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 TOLA_RS08455 99b7d004a3b5ff788a2089382bb819e9 351 Pfam PF02277 Phosphoribosyltransferase 11 342 2.1E-120 T 22-04-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 TOLA_RS08455 99b7d004a3b5ff788a2089382bb819e9 351 Gene3D G3DSA:1.10.1610.10 1 72 6.8E-29 T 22-04-2016 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 TOLA_RS08455 99b7d004a3b5ff788a2089382bb819e9 351 Gene3D G3DSA:3.40.50.10210 73 328 8.5E-100 T 22-04-2016 TOLA_RS08455 99b7d004a3b5ff788a2089382bb819e9 351 PANTHER PTHR21712 7 348 2.8E-104 T 22-04-2016 TOLA_RS08455 99b7d004a3b5ff788a2089382bb819e9 351 PANTHER PTHR21712:SF4 7 348 2.8E-104 T 22-04-2016 TOLA_RS08455 99b7d004a3b5ff788a2089382bb819e9 351 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 14 342 2.9E-118 T 22-04-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 TOLA_RS14790 be934d67f73bef8760d1a7eaa14b0419 245 PANTHER PTHR11751:SF389 1 107 1.5E-37 T 22-04-2016 TOLA_RS14790 be934d67f73bef8760d1a7eaa14b0419 245 SUPERFAMILY SSF48008 89 224 1.02E-25 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal TOLA_RS14790 be934d67f73bef8760d1a7eaa14b0419 245 SMART SM00345 12 71 2.2E-24 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS14790 be934d67f73bef8760d1a7eaa14b0419 245 PANTHER PTHR11751 1 107 1.5E-37 T 22-04-2016 TOLA_RS14790 be934d67f73bef8760d1a7eaa14b0419 245 Gene3D G3DSA:1.20.120.530 89 225 2.0E-29 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal TOLA_RS14790 be934d67f73bef8760d1a7eaa14b0419 245 SMART SM00895 91 217 5.3E-20 T 22-04-2016 IPR011711 GntR, C-terminal TOLA_RS14790 be934d67f73bef8760d1a7eaa14b0419 245 Gene3D G3DSA:1.10.10.10 7 74 1.4E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14790 be934d67f73bef8760d1a7eaa14b0419 245 Pfam PF07729 FCD domain 91 216 8.6E-20 T 22-04-2016 IPR011711 GntR, C-terminal TOLA_RS14790 be934d67f73bef8760d1a7eaa14b0419 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.8E-8 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS14790 be934d67f73bef8760d1a7eaa14b0419 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.8E-8 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS14790 be934d67f73bef8760d1a7eaa14b0419 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 3.3E-22 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS14790 be934d67f73bef8760d1a7eaa14b0419 245 SUPERFAMILY SSF46785 8 75 2.66E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 Gene3D G3DSA:3.30.450.20 9 113 4.8E-23 T 22-04-2016 TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 PANTHER PTHR24423 6 350 2.9E-146 T 22-04-2016 TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 SUPERFAMILY SSF55785 10 105 1.93E-10 T 22-04-2016 IPR000014 PAS domain TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 SMART SM00091 6 74 1.8E-5 T 22-04-2016 IPR000014 PAS domain TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 SUPERFAMILY SSF55874 198 347 4.71E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 SUPERFAMILY SSF47384 124 194 1.63E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 PRINTS PR00344 Bacterial sensor protein C-terminal signature 282 296 7.2E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 329 7.2E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 Pfam PF00989 PAS fold 10 112 5.1E-10 T 22-04-2016 IPR013767 PAS fold GO:0006355 TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 10 121 4.8E-6 T 22-04-2016 IPR000014 PAS domain TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 SMART SM00388 131 196 3.3E-16 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 Gene3D G3DSA:3.30.565.10 199 349 9.4E-38 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 237 349 3.6E-17 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 Gene3D G3DSA:1.10.287.130 128 188 8.2E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 Pfam PF00512 His Kinase A (phospho-acceptor) domain 133 192 1.9E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 PANTHER PTHR24423:SF488 6 350 2.9E-146 T 22-04-2016 TOLA_RS02375 ef535fd959a0cd77b2066f77ff8b88e4 350 SMART SM00387 235 350 2.7E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS06970 c90d5edf077d69924b867aeb98a2f0b2 427 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 14 425 2.8E-141 T 22-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS06970 c90d5edf077d69924b867aeb98a2f0b2 427 ProSitePatterns PS00885 EPSP synthase signature 2. 339 357 - T 22-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS06970 c90d5edf077d69924b867aeb98a2f0b2 427 PIRSF PIRSF000505 1 427 4.8E-155 T 22-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS06970 c90d5edf077d69924b867aeb98a2f0b2 427 Gene3D G3DSA:3.65.10.10 239 422 1.6E-70 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 TOLA_RS06970 c90d5edf077d69924b867aeb98a2f0b2 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 420 1.0E-155 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 TOLA_RS06970 c90d5edf077d69924b867aeb98a2f0b2 427 SUPERFAMILY SSF55205 1 424 2.75E-142 T 22-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TOLA_RS06970 c90d5edf077d69924b867aeb98a2f0b2 427 PANTHER PTHR21090 1 423 5.7E-204 T 22-04-2016 TOLA_RS06970 c90d5edf077d69924b867aeb98a2f0b2 427 ProSitePatterns PS00104 EPSP synthase signature 1. 90 104 - T 22-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS06970 c90d5edf077d69924b867aeb98a2f0b2 427 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 10 427 35.218 T 22-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS06970 c90d5edf077d69924b867aeb98a2f0b2 427 Gene3D G3DSA:3.65.10.10 22 238 1.1E-71 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 Gene3D G3DSA:1.10.10.60 164 212 3.0E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 Gene3D G3DSA:1.10.10.60 213 260 7.9E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 PANTHER PTHR11019 27 267 6.4E-48 T 22-04-2016 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 SUPERFAMILY SSF46689 213 260 1.97E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 213 255 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 Pfam PF12833 Helix-turn-helix domain 182 260 6.6E-18 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 Gene3D G3DSA:2.60.120.280 25 146 5.2E-17 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 SMART SM00342 176 259 3.5E-23 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 PANTHER PTHR11019:SF130 27 267 6.4E-48 T 22-04-2016 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 Pfam PF02311 AraC-like ligand binding domain 26 100 6.0E-10 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 SUPERFAMILY SSF51215 16 142 2.88E-17 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 259 4.5E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS09895 34dba32ee411587f2d6cb41bf0b70af3 270 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 228 243 4.5E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS04225 6ad6da6442c720705bebc4da1cb8018b 283 PANTHER PTHR21057:SF6 1 283 7.5E-211 T 22-04-2016 TOLA_RS04225 6ad6da6442c720705bebc4da1cb8018b 283 SUPERFAMILY SSF51569 3 278 2.84E-103 T 22-04-2016 TOLA_RS04225 6ad6da6442c720705bebc4da1cb8018b 283 Gene3D G3DSA:3.20.20.70 16 278 1.4E-104 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS04225 6ad6da6442c720705bebc4da1cb8018b 283 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 13 277 48.754 T 22-04-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 TOLA_RS04225 6ad6da6442c720705bebc4da1cb8018b 283 PANTHER PTHR21057 1 283 7.5E-211 T 22-04-2016 TOLA_RS04225 6ad6da6442c720705bebc4da1cb8018b 283 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 18 275 1.9E-116 T 22-04-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 TOLA_RS04225 6ad6da6442c720705bebc4da1cb8018b 283 Pfam PF00793 DAHP synthetase I family 10 275 8.3E-65 T 22-04-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 Gene3D G3DSA:3.30.360.10 164 318 4.9E-58 T 22-04-2016 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 155 1.3E-51 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 316 3.6E-51 T 22-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 SUPERFAMILY SSF51735 1 176 4.0E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 8.2E-28 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 8.2E-28 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 8.2E-28 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 8.2E-28 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 8.2E-28 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 SUPERFAMILY SSF55347 155 317 1.52E-54 T 22-04-2016 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 Hamap MF_01640 D-erythrose-4-phosphate dehydrogenase [epd]. 2 337 64.524 T 22-04-2016 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72|UniPathway: UPA00244 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 PANTHER PTHR10836 1 336 1.6E-237 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 SMART SM00846 3 155 8.7E-78 T 22-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 PIRSF PIRSF000149 1 337 5.5E-128 T 22-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 PANTHER PTHR10836:SF47 1 336 1.6E-237 T 22-04-2016 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 TIGRFAM TIGR01532 E4PD_g-proteo: erythrose-4-phosphate dehydrogenase 4 328 2.3E-183 T 22-04-2016 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72|UniPathway: UPA00244 TOLA_RS11935 0d3f7f612d0a7f70484b94fd38eeea60 338 Gene3D G3DSA:3.40.50.720 1 163 2.1E-63 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 Gene3D G3DSA:3.30.450.40 196 377 1.1E-28 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 SMART SM00267 371 543 1.5E-70 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 SUPERFAMILY SSF55073 387 542 3.66E-55 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 380 542 1.2E-45 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 Pfam PF00990 Diguanylate cyclase, GGDEF domain 382 539 1.6E-52 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 SMART SM00065 220 372 2.3E-8 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 Gene3D G3DSA:3.30.70.270 384 543 1.8E-61 T 22-04-2016 TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 SMART SM00091 84 150 9.1E-5 T 22-04-2016 IPR000014 PAS domain TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 SMART SM00086 156 198 1.0E-12 T 22-04-2016 IPR001610 PAC motif TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 PANTHER PTHR10799 346 539 2.2E-49 T 22-04-2016 TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 83 203 3.6E-24 T 22-04-2016 IPR000014 PAS domain TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 SUPERFAMILY SSF55785 90 196 7.09E-31 T 22-04-2016 IPR000014 PAS domain TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 SUPERFAMILY SSF55781 190 364 5.45E-30 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 Pfam PF13426 PAS domain 95 197 5.3E-17 T 22-04-2016 IPR000014 PAS domain TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 Gene3D G3DSA:3.30.450.20 93 195 8.4E-30 T 22-04-2016 TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 PANTHER PTHR10799:SF774 346 539 2.2E-49 T 22-04-2016 TOLA_RS06710 296548af9d841852c574d9a02ac8c8a8 543 Pfam PF13185 GAF domain 220 363 1.3E-15 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS10850 682baa9d9173c08619c1e98dfd777e5c 500 Gene3D G3DSA:3.30.1360.60 420 498 2.4E-25 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS10850 682baa9d9173c08619c1e98dfd777e5c 500 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 397 484 1.3E-22 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS10850 682baa9d9173c08619c1e98dfd777e5c 500 PANTHER PTHR30009 4 499 7.0E-214 T 22-04-2016 TOLA_RS10850 682baa9d9173c08619c1e98dfd777e5c 500 PANTHER PTHR30009:SF4 4 499 7.0E-214 T 22-04-2016 TOLA_RS10850 682baa9d9173c08619c1e98dfd777e5c 500 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 437 454 - T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS10850 682baa9d9173c08619c1e98dfd777e5c 500 SUPERFAMILY SSF55604 424 496 3.4E-18 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS10850 682baa9d9173c08619c1e98dfd777e5c 500 Pfam PF02378 Phosphotransferase system, EIIC 11 338 2.5E-67 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS10850 682baa9d9173c08619c1e98dfd777e5c 500 Pfam PF00367 phosphotransferase system, EIIB 428 459 1.7E-11 T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS10850 682baa9d9173c08619c1e98dfd777e5c 500 TIGRFAM TIGR01998 PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component 3 495 5.0E-196 T 22-04-2016 IPR010974 Phosphotransferase system, N-acetylglucosamine-specific IIBC component GO:0008982|GO:0009401|GO:0015572|GO:0016021|GO:0019866 TOLA_RS03255 940456b183ed1e7c68f62d0282d7449c 260 SMART SM00771 124 254 1.3E-40 T 22-04-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 TOLA_RS03255 940456b183ed1e7c68f62d0282d7449c 260 Gene3D G3DSA:3.30.1400.10 124 259 2.0E-46 T 22-04-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 TOLA_RS03255 940456b183ed1e7c68f62d0282d7449c 260 PANTHER PTHR38685 86 260 1.0E-43 T 22-04-2016 TOLA_RS03255 940456b183ed1e7c68f62d0282d7449c 260 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 127 255 3.0E-26 T 22-04-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 TOLA_RS03255 940456b183ed1e7c68f62d0282d7449c 260 PANTHER PTHR38685:SF1 86 260 1.0E-43 T 22-04-2016 TOLA_RS03255 940456b183ed1e7c68f62d0282d7449c 260 Hamap MF_00509 Cell division protein ZipA [zipA]. 2 256 22.261 T 22-04-2016 IPR011919 Cell division protein ZipA GO:0000917|GO:0007049|GO:0016021 TOLA_RS03255 940456b183ed1e7c68f62d0282d7449c 260 SUPERFAMILY SSF64383 124 258 1.07E-41 T 22-04-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 TOLA_RS03255 940456b183ed1e7c68f62d0282d7449c 260 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 106 253 2.4E-43 T 22-04-2016 IPR011919 Cell division protein ZipA GO:0000917|GO:0007049|GO:0016021 TOLA_RS03255 940456b183ed1e7c68f62d0282d7449c 260 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 127 252 2.3E-43 T 22-04-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 TOLA_RS10920 ad94be527aed69cf9abebe64d3b57051 224 SUPERFAMILY SSF56784 1 216 3.23E-52 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS10920 ad94be527aed69cf9abebe64d3b57051 224 PANTHER PTHR18901 1 217 1.7E-57 T 22-04-2016 TOLA_RS10920 ad94be527aed69cf9abebe64d3b57051 224 Gene3D G3DSA:1.10.150.240 16 83 7.6E-6 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 TOLA_RS10920 ad94be527aed69cf9abebe64d3b57051 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 148 168 1.7E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS10920 ad94be527aed69cf9abebe64d3b57051 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 130 146 1.7E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS10920 ad94be527aed69cf9abebe64d3b57051 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.7E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS10920 ad94be527aed69cf9abebe64d3b57051 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 99 112 1.7E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS10920 ad94be527aed69cf9abebe64d3b57051 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 175 188 1.7E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS10920 ad94be527aed69cf9abebe64d3b57051 224 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 51 184 5.6E-18 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS10920 ad94be527aed69cf9abebe64d3b57051 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 186 2.6E-37 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS10920 ad94be527aed69cf9abebe64d3b57051 224 Gene3D G3DSA:3.40.50.1000 1 15 3.0E-42 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS10920 ad94be527aed69cf9abebe64d3b57051 224 Gene3D G3DSA:3.40.50.1000 90 217 3.0E-42 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 TIGRFAM TIGR00492 alr: alanine racemase 4 357 7.5E-132 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 SUPERFAMILY SSF51419 8 235 1.7E-69 T 22-04-2016 IPR029066 PLP-binding barrel TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 SMART SM01005 234 358 2.3E-64 T 22-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 SUPERFAMILY SSF50621 226 357 3.49E-46 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 Gene3D G3DSA:2.40.37.10 213 357 6.0E-55 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 PANTHER PTHR30511 1 357 9.4E-210 T 22-04-2016 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 Gene3D G3DSA:3.20.20.10 11 212 2.2E-73 T 22-04-2016 IPR029066 PLP-binding barrel TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 PRINTS PR00992 Alanine racemase signature 250 265 1.5E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 PRINTS PR00992 Alanine racemase signature 267 282 1.5E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 PRINTS PR00992 Alanine racemase signature 27 43 1.5E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 PRINTS PR00992 Alanine racemase signature 121 133 1.5E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 PRINTS PR00992 Alanine racemase signature 156 167 1.5E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 PRINTS PR00992 Alanine racemase signature 193 220 1.5E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 PRINTS PR00992 Alanine racemase signature 340 353 1.5E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 PRINTS PR00992 Alanine racemase signature 288 305 1.5E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 PRINTS PR00992 Alanine racemase signature 61 79 1.5E-70 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 Pfam PF00842 Alanine racemase, C-terminal domain 234 356 2.6E-39 T 22-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 22-04-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 PANTHER PTHR30511:SF4 1 357 9.4E-210 T 22-04-2016 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 Hamap MF_01201 Alanine racemase. 1 358 35.197 T 22-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS13910 f158b4f9c72dda15383ec9f05f15080b 358 Pfam PF01168 Alanine racemase, N-terminal domain 8 220 6.9E-71 T 22-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 PANTHER PTHR23293:SF6 245 302 4.8E-95 T 22-04-2016 TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 PANTHER PTHR23293:SF6 1 158 4.8E-95 T 22-04-2016 TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 9 302 1.2E-164 T 22-04-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 Gene3D G3DSA:3.40.50.620 6 210 7.1E-62 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 Gene3D G3DSA:3.40.50.620 244 253 7.1E-62 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 PANTHER PTHR23293:SF6 178 211 4.8E-95 T 22-04-2016 TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 PANTHER PTHR23293 1 158 4.8E-95 T 22-04-2016 TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 29 257 2.6E-64 T 22-04-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 PANTHER PTHR23293 178 211 4.8E-95 T 22-04-2016 TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 PANTHER PTHR23293 245 302 4.8E-95 T 22-04-2016 TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 PIRSF PIRSF002936 2 302 1.0E-156 T 22-04-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 4 302 58.39 T 22-04-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 TOLA_RS12950 e6ab1d980d356b04291d11bed76632fc 302 SUPERFAMILY SSF52402 6 210 6.28E-73 T 22-04-2016 TOLA_RS05185 003232c61e3df3019d1b409fcaf7030e 357 PANTHER PTHR10361:SF31 8 352 4.7E-116 T 22-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TOLA_RS05185 003232c61e3df3019d1b409fcaf7030e 357 PIRSF PIRSF005508 4 355 1.3E-119 T 22-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TOLA_RS05185 003232c61e3df3019d1b409fcaf7030e 357 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 17 344 1.1E-120 T 22-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TOLA_RS05185 003232c61e3df3019d1b409fcaf7030e 357 PANTHER PTHR10361 8 352 4.7E-116 T 22-04-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 TOLA_RS05185 003232c61e3df3019d1b409fcaf7030e 357 Pfam PF01758 Sodium Bile acid symporter family 63 257 4.0E-37 T 22-04-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 TOLA_RS00090 d610880b01fbc2366b0e686a62c2046c 82 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 12 36 - T 22-04-2016 IPR001455 TusA-like domain TOLA_RS00090 d610880b01fbc2366b0e686a62c2046c 82 Gene3D G3DSA:3.30.110.40 6 80 6.6E-31 T 22-04-2016 IPR001455 TusA-like domain TOLA_RS00090 d610880b01fbc2366b0e686a62c2046c 82 Pfam PF01206 Sulfurtransferase TusA 11 79 8.0E-25 T 22-04-2016 IPR001455 TusA-like domain TOLA_RS00090 d610880b01fbc2366b0e686a62c2046c 82 PANTHER PTHR33279:SF5 1 80 2.9E-48 T 22-04-2016 TOLA_RS00090 d610880b01fbc2366b0e686a62c2046c 82 PANTHER PTHR33279 1 80 2.9E-48 T 22-04-2016 TOLA_RS00090 d610880b01fbc2366b0e686a62c2046c 82 Hamap MF_00413 Sulfurtransferase TusA [tusA]. 3 81 28.696 T 22-04-2016 IPR022931 Sulphurtransferase TusA GO:0016783 TOLA_RS00090 d610880b01fbc2366b0e686a62c2046c 82 SUPERFAMILY SSF64307 7 79 1.12E-26 T 22-04-2016 IPR001455 TusA-like domain TOLA_RS12045 25807fdf2b7106ca836664fef98ce3c6 329 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 3 325 35.963 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 TOLA_RS12045 25807fdf2b7106ca836664fef98ce3c6 329 PANTHER PTHR30004 1 328 2.3E-204 T 22-04-2016 TOLA_RS12045 25807fdf2b7106ca836664fef98ce3c6 329 SUPERFAMILY SSF53659 4 327 9.32E-116 T 22-04-2016 TOLA_RS12045 25807fdf2b7106ca836664fef98ce3c6 329 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 33 321 2.3E-110 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 TOLA_RS12045 25807fdf2b7106ca836664fef98ce3c6 329 PANTHER PTHR30004:SF5 1 328 2.3E-204 T 22-04-2016 TOLA_RS12045 25807fdf2b7106ca836664fef98ce3c6 329 Gene3D G3DSA:3.40.718.10 2 328 1.3E-136 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 TOLA_RS12045 25807fdf2b7106ca836664fef98ce3c6 329 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 324 4.6E-131 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 SMART SM00332 1 232 3.9E-19 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 PANTHER PTHR24362:SF160 264 519 3.6E-45 T 22-04-2016 TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 PANTHER PTHR24362 264 519 3.6E-45 T 22-04-2016 TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 Pfam PF13672 Protein phosphatase 2C 11 199 2.3E-19 T 22-04-2016 TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 Gene3D G3DSA:3.30.200.20 262 334 2.8E-5 T 22-04-2016 TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 Gene3D G3DSA:3.60.40.10 4 233 2.0E-45 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 SMART SM00220 267 524 1.5E-22 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 SUPERFAMILY SSF81606 6 234 1.19E-48 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 386 398 - T 22-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 Gene3D G3DSA:1.10.510.10 335 519 2.1E-41 T 22-04-2016 TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 SMART SM00331 7 234 1.1E-15 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 SUPERFAMILY SSF56112 249 528 5.8E-54 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS08970 9748a58a5ea0112313032a0cb8af7eeb 575 Pfam PF00069 Protein kinase domain 267 518 4.1E-36 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 PANTHER PTHR11817:SF17 1 478 1.3E-296 T 22-04-2016 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 Gene3D G3DSA:3.20.20.60 3 73 7.4E-91 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 Gene3D G3DSA:3.20.20.60 170 328 7.4E-91 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 SUPERFAMILY SSF50800 71 166 7.5E-25 T 22-04-2016 IPR011037 Pyruvate kinase-like, insert domain TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 PRINTS PR01050 Pyruvate kinase family signature 272 296 2.6E-50 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 PRINTS PR01050 Pyruvate kinase family signature 60 76 2.6E-50 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 PRINTS PR01050 Pyruvate kinase family signature 220 246 2.6E-50 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 PRINTS PR01050 Pyruvate kinase family signature 297 315 2.6E-50 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 PRINTS PR01050 Pyruvate kinase family signature 316 332 2.6E-50 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 PRINTS PR01050 Pyruvate kinase family signature 247 271 2.6E-50 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 PRINTS PR01050 Pyruvate kinase family signature 187 201 2.6E-50 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 22-04-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 Pfam PF00224 Pyruvate kinase, barrel domain 3 341 2.3E-125 T 22-04-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 PANTHER PTHR11817 1 478 1.3E-296 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 Pfam PF02887 Pyruvate kinase, alpha/beta domain 360 475 3.7E-26 T 22-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 SUPERFAMILY SSF51621 168 342 1.37E-83 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 SUPERFAMILY SSF51621 2 76 1.37E-83 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 SUPERFAMILY SSF52935 326 478 1.06E-36 T 22-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 477 3.4E-165 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 Gene3D G3DSA:2.40.33.10 74 169 1.1E-27 T 22-04-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS05245 f78b9ec473c0d39dcbc4b68a11c8c048 479 Gene3D G3DSA:3.40.1380.20 329 474 5.0E-36 T 22-04-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS06720 97975b379fbb365d9480f4824abb4505 329 SUPERFAMILY SSF55347 127 291 5.89E-29 T 22-04-2016 TOLA_RS06720 97975b379fbb365d9480f4824abb4505 329 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 119 1.5E-27 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 TOLA_RS06720 97975b379fbb365d9480f4824abb4505 329 Gene3D G3DSA:3.40.50.720 1 142 3.4E-49 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS06720 97975b379fbb365d9480f4824abb4505 329 PANTHER PTHR22604:SF76 1 318 4.6E-116 T 22-04-2016 TOLA_RS06720 97975b379fbb365d9480f4824abb4505 329 SUPERFAMILY SSF51735 2 152 2.34E-49 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS06720 97975b379fbb365d9480f4824abb4505 329 PANTHER PTHR22604 1 318 4.6E-116 T 22-04-2016 TOLA_RS06720 97975b379fbb365d9480f4824abb4505 329 Gene3D G3DSA:3.30.360.10 143 327 1.1E-69 T 22-04-2016 TOLA_RS00795 34389e34d9baa27327dc07004ae4cf16 366 Pfam PF01476 LysM domain 36 82 1.1E-12 T 22-04-2016 IPR018392 LysM domain TOLA_RS00795 34389e34d9baa27327dc07004ae4cf16 366 Gene3D G3DSA:3.10.350.10 35 82 7.3E-8 T 22-04-2016 IPR018392 LysM domain TOLA_RS00795 34389e34d9baa27327dc07004ae4cf16 366 PANTHER PTHR34700:SF2 1 365 2.1E-49 T 22-04-2016 TOLA_RS00795 34389e34d9baa27327dc07004ae4cf16 366 SMART SM00257 35 83 4.4E-6 T 22-04-2016 IPR018392 LysM domain TOLA_RS00795 34389e34d9baa27327dc07004ae4cf16 366 PANTHER PTHR34700 1 365 2.1E-49 T 22-04-2016 TOLA_RS00795 34389e34d9baa27327dc07004ae4cf16 366 SUPERFAMILY SSF54106 35 82 3.53E-7 T 22-04-2016 IPR018392 LysM domain TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 Gene3D G3DSA:1.20.120.160 546 655 2.9E-20 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 SMART SM00073 558 656 6.6E-5 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 SUPERFAMILY SSF55874 209 387 3.67E-44 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 SMART SM00448 406 520 2.3E-36 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 SMART SM00387 267 388 6.0E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 385 3.6E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 366 3.6E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 327 3.6E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 PRINTS PR00344 Bacterial sensor protein C-terminal signature 331 341 3.6E-15 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 Pfam PF00512 His Kinase A (phospho-acceptor) domain 155 220 3.6E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 Gene3D G3DSA:3.40.50.2300 403 524 5.9E-42 T 22-04-2016 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 PANTHER PTHR24423:SF491 128 563 8.7E-154 T 22-04-2016 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 268 387 1.8E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 SUPERFAMILY SSF47226 543 657 1.7E-20 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 SUPERFAMILY SSF47384 140 221 1.35E-21 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 Gene3D G3DSA:1.10.287.130 147 208 1.7E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 SUPERFAMILY SSF52172 406 524 3.13E-39 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 Gene3D G3DSA:3.30.565.10 209 388 5.9E-43 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 Pfam PF00072 Response regulator receiver domain 408 519 5.9E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 SMART SM00388 155 220 2.5E-23 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 PANTHER PTHR24423 128 563 8.7E-154 T 22-04-2016 TOLA_RS07095 a03886f7863e7d68d150eeeca6a469aa 659 Pfam PF01627 Hpt domain 569 644 3.6E-11 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 TOLA_RS09665 e8f7f4369cea3820d6569dfbacfec73d 766 Pfam PF02901 Pyruvate formate lyase-like 3 627 2.0E-198 T 22-04-2016 IPR004184 Pyruvate formate lyase domain GO:0003824 TOLA_RS09665 e8f7f4369cea3820d6569dfbacfec73d 766 PANTHER PTHR30191:SF4 3 766 0.0 T 22-04-2016 TOLA_RS09665 e8f7f4369cea3820d6569dfbacfec73d 766 SUPERFAMILY SSF51998 2 765 3.05E-212 T 22-04-2016 TOLA_RS09665 e8f7f4369cea3820d6569dfbacfec73d 766 ProSitePatterns PS00850 Glycine radical domain signature. 737 745 - T 22-04-2016 IPR019777 Formate C-acetyltransferase glycine radical, conserved site TOLA_RS09665 e8f7f4369cea3820d6569dfbacfec73d 766 Pfam PF01228 Glycine radical 647 748 6.7E-26 T 22-04-2016 IPR001150 Glycine radical domain GO:0003824|GO:0008152 TOLA_RS09665 e8f7f4369cea3820d6569dfbacfec73d 766 Gene3D G3DSA:3.20.70.20 2 765 4.0E-246 T 22-04-2016 TOLA_RS09665 e8f7f4369cea3820d6569dfbacfec73d 766 PANTHER PTHR30191 3 766 0.0 T 22-04-2016 TOLA_RS09665 e8f7f4369cea3820d6569dfbacfec73d 766 TIGRFAM TIGR01774 PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family 1 766 0.0 T 22-04-2016 IPR010098 Glycyl radical enzyme, PFL2/glycerol dehydratase family KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493|UniPathway: UPA00920 TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 2.15E-60 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 2.15E-60 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 2.15E-60 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 2.15E-60 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 2.15E-60 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 2.15E-60 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 SUPERFAMILY SSF50249 3 123 4.03E-52 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 Gene3D G3DSA:2.40.50.140 1 123 3.7E-65 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 PANTHER PTHR11652 1 116 2.2E-75 T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 2.2E-70 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.507 T 22-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 PIRSF PIRSF002133 1 124 4.1E-54 T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS14220 22628968e766729a3233a61685d7bfba 124 Pfam PF00164 Ribosomal protein S12/S23 8 123 1.5E-42 T 22-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 Gene3D G3DSA:3.10.150.10 249 367 4.0E-39 T 22-04-2016 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 SMART SM00480 17 363 6.0E-143 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 244 2.0E-34 T 22-04-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 Gene3D G3DSA:3.10.150.10 126 248 2.1E-34 T 22-04-2016 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 246 366 2.5E-41 T 22-04-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 SUPERFAMILY SSF55979 127 245 1.63E-26 T 22-04-2016 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 PIRSF PIRSF000804 1 367 3.3E-113 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 Gene3D G3DSA:3.10.150.10 1 121 1.8E-28 T 22-04-2016 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 SUPERFAMILY SSF55979 246 367 4.19E-38 T 22-04-2016 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 367 1.2E-106 T 22-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 SUPERFAMILY SSF55979 1 118 3.49E-26 T 22-04-2016 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 PANTHER PTHR30478 2 367 4.6E-135 T 22-04-2016 TOLA_RS00010 d53106230ee7132a61fe26f1de92fd27 367 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 119 7.0E-35 T 22-04-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS05365 74c675dfafd9270c422793efd94030b4 496 PANTHER PTHR10196 4 496 1.4E-197 T 22-04-2016 TOLA_RS05365 74c675dfafd9270c422793efd94030b4 496 SUPERFAMILY SSF53067 5 244 1.94E-46 T 22-04-2016 TOLA_RS05365 74c675dfafd9270c422793efd94030b4 496 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 220 1.4E-34 T 22-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TOLA_RS05365 74c675dfafd9270c422793efd94030b4 496 TIGRFAM TIGR02627 rhamnulo_kin: rhamnulokinase 7 457 1.8E-199 T 22-04-2016 IPR013449 Rhamnulokinase GO:0008993|GO:0019301 KEGG: 00040+2.7.1.5|KEGG: 00051+2.7.1.5|UniPathway: UPA00541 TOLA_RS05365 74c675dfafd9270c422793efd94030b4 496 Gene3D G3DSA:3.30.420.40 5 224 3.5E-30 T 22-04-2016 TOLA_RS05365 74c675dfafd9270c422793efd94030b4 496 Gene3D G3DSA:3.30.420.40 251 482 3.2E-16 T 22-04-2016 TOLA_RS05365 74c675dfafd9270c422793efd94030b4 496 PANTHER PTHR10196:SF6 4 496 1.4E-197 T 22-04-2016 TOLA_RS05365 74c675dfafd9270c422793efd94030b4 496 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 252 433 1.7E-29 T 22-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TOLA_RS05365 74c675dfafd9270c422793efd94030b4 496 SUPERFAMILY SSF53067 251 455 1.73E-32 T 22-04-2016 TOLA_RS10675 1a63304d7028f0da5b1b9c204581ed95 263 PANTHER PTHR23416:SF8 1 254 1.6E-129 T 22-04-2016 TOLA_RS10675 1a63304d7028f0da5b1b9c204581ed95 263 Gene3D G3DSA:1.20.1180.10 197 262 3.5E-25 T 22-04-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 TOLA_RS10675 1a63304d7028f0da5b1b9c204581ed95 263 Gene3D G3DSA:2.160.10.10 5 194 4.1E-51 T 22-04-2016 TOLA_RS10675 1a63304d7028f0da5b1b9c204581ed95 263 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 8 260 8.3E-102 T 22-04-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 TOLA_RS10675 1a63304d7028f0da5b1b9c204581ed95 263 PANTHER PTHR23416 1 254 1.6E-129 T 22-04-2016 TOLA_RS10675 1a63304d7028f0da5b1b9c204581ed95 263 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 5 262 44.874 T 22-04-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 TOLA_RS10675 1a63304d7028f0da5b1b9c204581ed95 263 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 180 261 4.4E-28 T 22-04-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 TOLA_RS10675 1a63304d7028f0da5b1b9c204581ed95 263 PIRSF PIRSF000456 5 263 6.6E-104 T 22-04-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 TOLA_RS10675 1a63304d7028f0da5b1b9c204581ed95 263 SUPERFAMILY SSF51161 2 262 5.26E-80 T 22-04-2016 IPR011004 Trimeric LpxA-like TOLA_RS10675 1a63304d7028f0da5b1b9c204581ed95 263 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 36 62 1.2E-4 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS10675 1a63304d7028f0da5b1b9c204581ed95 263 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 4 32 7.0E-6 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS10675 1a63304d7028f0da5b1b9c204581ed95 263 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 143 2.4E-7 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 Pfam PF12833 Helix-turn-helix domain 193 271 2.8E-22 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 SUPERFAMILY SSF51215 23 156 1.96E-14 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 Gene3D G3DSA:2.60.120.280 27 157 2.4E-13 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 PANTHER PTHR11019 20 275 5.9E-63 T 22-04-2016 TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 Gene3D G3DSA:1.10.10.60 223 273 1.2E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 SMART SM00342 186 269 1.0E-27 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 SUPERFAMILY SSF46689 172 219 3.36E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 PANTHER PTHR11019:SF86 20 275 5.9E-63 T 22-04-2016 TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 253 269 1.2E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 238 253 1.2E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 Gene3D G3DSA:1.10.10.60 166 222 4.0E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 SUPERFAMILY SSF46689 222 273 3.12E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS05370 1ddf053cb81863538931134553753ee3 275 Pfam PF02311 AraC-like ligand binding domain 21 150 7.0E-15 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 534 665 7.4E-42 T 22-04-2016 IPR020992 Tail specific protease, C-terminal TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 Gene3D G3DSA:2.30.42.10 248 338 8.5E-19 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 Gene3D G3DSA:3.90.226.10 339 532 1.2E-61 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 SMART SM00245 329 530 6.2E-61 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 PANTHER PTHR32060 5 603 6.7E-282 T 22-04-2016 TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 202 550 2.4E-111 T 22-04-2016 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 Pfam PF03572 Peptidase family S41 359 528 1.6E-48 T 22-04-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 SMART SM00228 248 325 3.5E-10 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 242 322 4.5E-11 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 SUPERFAMILY SSF50156 247 327 1.29E-11 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 PANTHER PTHR32060:SF11 5 603 6.7E-282 T 22-04-2016 TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 SUPERFAMILY SSF52096 353 542 1.24E-67 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS05575 1cdd5fff939ea320b117c3d510a8bba0 670 SUPERFAMILY SSF52096 169 266 1.24E-67 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 Gene3D G3DSA:3.40.50.880 4 190 4.0E-54 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 Pfam PF00117 Glutamine amidotransferase class-I 7 188 1.7E-43 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 SUPERFAMILY SSF52317 5 188 1.64E-44 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 PRINTS PR00097 Anthranilate synthase component II signature 81 92 1.3E-34 T 22-04-2016 TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 PRINTS PR00097 Anthranilate synthase component II signature 106 114 1.3E-34 T 22-04-2016 TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 PRINTS PR00097 Anthranilate synthase component II signature 168 181 1.3E-34 T 22-04-2016 TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 PRINTS PR00097 Anthranilate synthase component II signature 5 19 1.3E-34 T 22-04-2016 TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 PRINTS PR00097 Anthranilate synthase component II signature 54 63 1.3E-34 T 22-04-2016 TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 PRINTS PR00097 Anthranilate synthase component II signature 126 138 1.3E-34 T 22-04-2016 TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 PANTHER PTHR11922:SF25 5 192 6.5E-79 T 22-04-2016 TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 PANTHER PTHR11922 5 192 6.5E-79 T 22-04-2016 TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 5 186 1.1E-52 T 22-04-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 6.5E-14 T 22-04-2016 TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 6.5E-14 T 22-04-2016 TOLA_RS04840 db154e6b9d1a13935fe71c2ee8b2b4d9 199 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 6.5E-14 T 22-04-2016 TOLA_RS06650 6314784d4efe0cffbeea25761e371d3b 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 130 1.0E-12 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TOLA_RS06650 6314784d4efe0cffbeea25761e371d3b 140 PANTHER PTHR36503 2 134 4.6E-44 T 22-04-2016 TOLA_RS06650 6314784d4efe0cffbeea25761e371d3b 140 PANTHER PTHR36503:SF1 2 134 4.6E-44 T 22-04-2016 TOLA_RS06650 6314784d4efe0cffbeea25761e371d3b 140 Gene3D G3DSA:3.10.180.10 1 134 9.9E-41 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TOLA_RS06650 6314784d4efe0cffbeea25761e371d3b 140 SUPERFAMILY SSF54593 5 135 1.2E-28 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TOLA_RS10115 0606f445b5ce54b1e12dd6885bb24753 179 PANTHER PTHR10204 1 173 3.4E-31 T 22-04-2016 TOLA_RS10115 0606f445b5ce54b1e12dd6885bb24753 179 PANTHER PTHR10204:SF42 1 173 3.4E-31 T 22-04-2016 TOLA_RS10115 0606f445b5ce54b1e12dd6885bb24753 179 Gene3D G3DSA:3.40.50.360 1 172 3.9E-37 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS10115 0606f445b5ce54b1e12dd6885bb24753 179 SUPERFAMILY SSF52218 1 172 2.72E-39 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS10115 0606f445b5ce54b1e12dd6885bb24753 179 Pfam PF02525 Flavodoxin-like fold 1 168 1.1E-34 T 22-04-2016 IPR003680 Flavodoxin-like fold TOLA_RS07670 d9b518d2de18d63a6647c2ab63213511 570 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 204 376 1.8E-45 T 22-04-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain TOLA_RS07670 d9b518d2de18d63a6647c2ab63213511 570 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 477 560 3.4E-23 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 TOLA_RS07670 d9b518d2de18d63a6647c2ab63213511 570 SUPERFAMILY SSF52833 8 158 2.68E-42 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS07670 d9b518d2de18d63a6647c2ab63213511 570 SUPERFAMILY SSF140490 471 563 2.35E-25 T 22-04-2016 TOLA_RS07670 d9b518d2de18d63a6647c2ab63213511 570 PANTHER PTHR11780 195 561 1.2E-154 T 22-04-2016 TOLA_RS07670 d9b518d2de18d63a6647c2ab63213511 570 SUPERFAMILY SSF142019 180 396 2.35E-76 T 22-04-2016 TOLA_RS07670 d9b518d2de18d63a6647c2ab63213511 570 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 488 499 - T 22-04-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 TOLA_RS07670 d9b518d2de18d63a6647c2ab63213511 570 SUPERFAMILY SSF142984 398 466 1.31E-13 T 22-04-2016 TOLA_RS07670 d9b518d2de18d63a6647c2ab63213511 570 PANTHER PTHR11780:SF0 195 561 1.2E-154 T 22-04-2016 TOLA_RS07670 d9b518d2de18d63a6647c2ab63213511 570 SMART SM00928 475 520 4.6E-13 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 TOLA_RS07670 d9b518d2de18d63a6647c2ab63213511 570 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 15 156 3.8E-43 T 22-04-2016 TOLA_RS03100 808e09e85b8657621557fcda3dc0f1f4 211 SUPERFAMILY SSF50475 14 211 5.61E-66 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 TOLA_RS03100 808e09e85b8657621557fcda3dc0f1f4 211 PANTHER PTHR10851:SF0 1 211 1.7E-107 T 22-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 TOLA_RS03100 808e09e85b8657621557fcda3dc0f1f4 211 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 34 116 3.4E-23 T 22-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 TOLA_RS03100 808e09e85b8657621557fcda3dc0f1f4 211 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 1 211 4.2E-92 T 22-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 TOLA_RS03100 808e09e85b8657621557fcda3dc0f1f4 211 PANTHER PTHR10851 1 211 1.7E-107 T 22-04-2016 TOLA_RS03100 808e09e85b8657621557fcda3dc0f1f4 211 PIRSF PIRSF000190 1 211 1.8E-79 T 22-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 TOLA_RS03100 808e09e85b8657621557fcda3dc0f1f4 211 Gene3D G3DSA:2.30.110.10 15 211 5.3E-82 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 TOLA_RS03100 808e09e85b8657621557fcda3dc0f1f4 211 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 181 194 - T 22-04-2016 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 TOLA_RS03100 808e09e85b8657621557fcda3dc0f1f4 211 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 171 211 1.5E-18 T 22-04-2016 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 TOLA_RS03100 808e09e85b8657621557fcda3dc0f1f4 211 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 9 211 37.914 T 22-04-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 TOLA_RS14675 eb343e1976e3e689253a9b861fba0c2d 423 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 346 422 6.5E-7 T 22-04-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain TOLA_RS14675 eb343e1976e3e689253a9b861fba0c2d 423 Pfam PF01943 Polysaccharide biosynthesis protein 4 291 4.8E-21 T 22-04-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TOLA_RS07160 775aa8539a4665060d7c759e022a6e13 152 PANTHER PTHR31503 1 130 1.2E-41 T 22-04-2016 TOLA_RS07160 775aa8539a4665060d7c759e022a6e13 152 PANTHER PTHR31503:SF17 1 130 1.2E-41 T 22-04-2016 TOLA_RS07160 775aa8539a4665060d7c759e022a6e13 152 Pfam PF03733 Inner membrane component domain 76 125 1.2E-16 T 22-04-2016 IPR005185 Inner membrane component domain TOLA_RS07160 775aa8539a4665060d7c759e022a6e13 152 Pfam PF03733 Inner membrane component domain 4 54 1.4E-14 T 22-04-2016 IPR005185 Inner membrane component domain TOLA_RS07160 775aa8539a4665060d7c759e022a6e13 152 PIRSF PIRSF028777 1 138 1.1E-49 T 22-04-2016 IPR031308 Uncharacterised conserved protein UCP028777 TOLA_RS01565 f0fb073fc0f10bfcc641b29b25bcd286 225 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 10 217 6.3E-67 T 22-04-2016 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 TOLA_RS01565 f0fb073fc0f10bfcc641b29b25bcd286 225 PANTHER PTHR30183 6 221 5.6E-62 T 22-04-2016 TOLA_RS01565 f0fb073fc0f10bfcc641b29b25bcd286 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 213 8.5E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS01565 f0fb073fc0f10bfcc641b29b25bcd286 225 Gene3D G3DSA:1.10.3720.10 5 212 7.4E-39 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS01565 f0fb073fc0f10bfcc641b29b25bcd286 225 SUPERFAMILY SSF161098 6 216 3.79E-46 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 332 347 - T 22-04-2016 IPR033136 NAD-dependent DNA ligase, conserved site TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 SMART SM00278 513 532 310.0 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 SMART SM00278 481 500 0.16 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 SMART SM00278 545 564 240.0 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 SMART SM00278 447 466 0.68 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 323 398 2.1E-36 T 22-04-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 SUPERFAMILY SSF47781 405 579 5.56E-62 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Gene3D G3DSA:1.10.287.610 2 66 2.5E-24 T 22-04-2016 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 408 435 2.3E-8 T 22-04-2016 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Gene3D G3DSA:2.40.50.140 321 392 1.0E-35 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 PIRSF PIRSF001604 1 678 2.1E-242 T 22-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 SUPERFAMILY SSF52113 601 675 9.91E-19 T 22-04-2016 IPR001357 BRCT domain TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 SMART SM00532 3 449 9.0E-261 T 22-04-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 SUPERFAMILY SSF56091 2 317 3.31E-116 T 22-04-2016 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 3 319 1.5E-126 T 22-04-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Hamap MF_01588 DNA ligase [ligA]. 2 674 51.946 T 22-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Gene3D G3DSA:3.30.470.30 119 253 2.3E-50 T 22-04-2016 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 115 144 - T 22-04-2016 IPR018239 NAD-dependent DNA ligase, active site TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 SMART SM00292 600 677 2.4E-13 T 22-04-2016 IPR001357 BRCT domain TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 601 674 6.7E-13 T 22-04-2016 IPR001357 BRCT domain TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 SUPERFAMILY SSF50249 319 399 6.34E-29 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 PANTHER PTHR23389:SF9 1 533 1.5E-200 T 22-04-2016 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Pfam PF14520 Helix-hairpin-helix domain 447 502 5.9E-7 T 22-04-2016 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Pfam PF12826 Helix-hairpin-helix motif 511 574 5.9E-23 T 22-04-2016 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Gene3D G3DSA:3.40.50.10190 602 675 1.0E-23 T 22-04-2016 IPR001357 BRCT domain TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 PANTHER PTHR23389 1 533 1.5E-200 T 22-04-2016 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Gene3D G3DSA:1.10.150.20 505 579 8.7E-29 T 22-04-2016 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 11 670 7.1E-258 T 22-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TOLA_RS03260 35b4b692c41047064db50879b80112e5 686 Gene3D G3DSA:1.10.150.20 436 503 2.6E-30 T 22-04-2016 TOLA_RS01000 a69e316c0b9959abce804feeecce18ca 286 PANTHER PTHR30636 1 286 2.6E-106 T 22-04-2016 TOLA_RS01000 a69e316c0b9959abce804feeecce18ca 286 Pfam PF03755 YicC-like family, N-terminal region 2 152 5.8E-41 T 22-04-2016 IPR013527 YicC-like, N-terminal TOLA_RS01000 a69e316c0b9959abce804feeecce18ca 286 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 286 5.3E-114 T 22-04-2016 IPR005229 Conserved hypothetical protein CHP00255 TOLA_RS01000 a69e316c0b9959abce804feeecce18ca 286 Pfam PF08340 Domain of unknown function (DUF1732) 202 286 2.6E-34 T 22-04-2016 IPR013551 Domain of unknown function DUF1732 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 Pfam PF00009 Elongation factor Tu GTP binding domain 4 194 1.4E-56 T 22-04-2016 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 PANTHER PTHR23115:SF14 3 593 8.3E-295 T 22-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 Pfam PF03144 Elongation factor Tu domain 2 219 289 5.5E-11 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 SUPERFAMILY SSF54980 398 513 4.17E-25 T 22-04-2016 IPR009022 Elongation factor G, III-V domain TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 Gene3D G3DSA:2.40.30.10 206 303 7.5E-27 T 22-04-2016 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 PRINTS PR00315 GTP-binding elongation factor signature 87 98 1.8E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 PRINTS PR00315 GTP-binding elongation factor signature 51 59 1.8E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 PRINTS PR00315 GTP-binding elongation factor signature 7 20 1.8E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 PRINTS PR00315 GTP-binding elongation factor signature 123 132 1.8E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 PRINTS PR00315 GTP-binding elongation factor signature 71 81 1.8E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 SUPERFAMILY SSF54980 302 387 2.09E-15 T 22-04-2016 IPR009022 Elongation factor G, III-V domain TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 139 2.6E-23 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 SUPERFAMILY SSF50447 151 299 7.07E-33 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 599 2.5E-287 T 22-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 Pfam PF00679 Elongation factor G C-terminus 396 477 4.6E-21 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 Gene3D G3DSA:2.40.50.250 483 577 5.7E-42 T 22-04-2016 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 Gene3D G3DSA:3.30.70.870 304 399 1.2E-36 T 22-04-2016 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 Gene3D G3DSA:3.40.50.300 3 205 6.4E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 PANTHER PTHR23115 3 593 8.3E-295 T 22-04-2016 TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 SUPERFAMILY SSF52540 3 219 1.19E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02390 1b58bfdc73b6145eb417dfcbe2dfdf64 608 Gene3D G3DSA:3.30.70.240 400 478 4.0E-30 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain TOLA_RS12065 a4e3e9cbf3c493c4e548d1872010755f 163 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 14 36 - T 22-04-2016 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 TOLA_RS12065 a4e3e9cbf3c493c4e548d1872010755f 163 Gene3D G3DSA:3.40.430.10 1 161 4.0E-63 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain TOLA_RS12065 a4e3e9cbf3c493c4e548d1872010755f 163 PRINTS PR00070 Dihydrofolate reductase signature 28 36 5.6E-17 T 22-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 TOLA_RS12065 a4e3e9cbf3c493c4e548d1872010755f 163 PRINTS PR00070 Dihydrofolate reductase signature 14 24 5.6E-17 T 22-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 TOLA_RS12065 a4e3e9cbf3c493c4e548d1872010755f 163 PRINTS PR00070 Dihydrofolate reductase signature 41 52 5.6E-17 T 22-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 TOLA_RS12065 a4e3e9cbf3c493c4e548d1872010755f 163 PRINTS PR00070 Dihydrofolate reductase signature 92 106 5.6E-17 T 22-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 TOLA_RS12065 a4e3e9cbf3c493c4e548d1872010755f 163 SUPERFAMILY SSF53597 1 161 1.3E-58 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain TOLA_RS12065 a4e3e9cbf3c493c4e548d1872010755f 163 PIRSF PIRSF000194 1 163 5.0E-63 T 22-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 TOLA_RS12065 a4e3e9cbf3c493c4e548d1872010755f 163 Pfam PF00186 Dihydrofolate reductase 2 161 1.6E-62 T 22-04-2016 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 TOLA_RS12065 a4e3e9cbf3c493c4e548d1872010755f 163 PANTHER PTHR22778:SF16 1 161 1.7E-45 T 22-04-2016 TOLA_RS12065 a4e3e9cbf3c493c4e548d1872010755f 163 PANTHER PTHR22778 1 161 1.7E-45 T 22-04-2016 TOLA_RS06270 a4bc702aa02795286782248db7d38b6f 211 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 52 66 - T 22-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS06270 a4bc702aa02795286782248db7d38b6f 211 Pfam PF00849 RNA pseudouridylate synthase 16 159 5.0E-24 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS06270 a4bc702aa02795286782248db7d38b6f 211 PANTHER PTHR11079 10 196 6.0E-66 T 22-04-2016 TOLA_RS06270 a4bc702aa02795286782248db7d38b6f 211 SUPERFAMILY SSF55120 9 204 8.16E-49 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS06270 a4bc702aa02795286782248db7d38b6f 211 TIGRFAM TIGR01621 RluA-like: pseudouridine synthase Rlu family protein, TIGR01621 8 200 1.3E-77 T 22-04-2016 IPR006508 Pseudouridine synthase, RluA-like KEGG: 00627+5.4.99.- TOLA_RS06270 a4bc702aa02795286782248db7d38b6f 211 PANTHER PTHR11079:SF62 10 196 6.0E-66 T 22-04-2016 TOLA_RS10890 f72d35a8e9f7ef4f7a3f995434cdb644 185 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 161 2.1E-23 T 22-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type TOLA_RS10890 f72d35a8e9f7ef4f7a3f995434cdb644 185 PANTHER PTHR11124:SF14 1 160 1.4E-42 T 22-04-2016 TOLA_RS10890 f72d35a8e9f7ef4f7a3f995434cdb644 185 PANTHER PTHR11124 1 160 1.4E-42 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 TOLA_RS10890 f72d35a8e9f7ef4f7a3f995434cdb644 185 Gene3D G3DSA:3.60.21.10 4 164 3.2E-41 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS10890 f72d35a8e9f7ef4f7a3f995434cdb644 185 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 4 167 2.4E-24 T 22-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 TOLA_RS10890 f72d35a8e9f7ef4f7a3f995434cdb644 185 SUPERFAMILY SSF56300 3 164 1.52E-33 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS14650 8e2a451cf41bbac17b58a57ea62e1f7a 359 SMART SM00854 2 232 1.2E-39 T 22-04-2016 IPR019079 Capsule synthesis protein, CapA TOLA_RS14650 8e2a451cf41bbac17b58a57ea62e1f7a 359 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 3 231 5.7E-41 T 22-04-2016 IPR019079 Capsule synthesis protein, CapA TOLA_RS14650 8e2a451cf41bbac17b58a57ea62e1f7a 359 PANTHER PTHR33393 25 260 2.1E-33 T 22-04-2016 TOLA_RS14650 8e2a451cf41bbac17b58a57ea62e1f7a 359 PANTHER PTHR33393:SF2 25 260 2.1E-33 T 22-04-2016 TOLA_RS14650 8e2a451cf41bbac17b58a57ea62e1f7a 359 SUPERFAMILY SSF56300 1 240 1.2E-21 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS06205 68e6d3ebbb4ca2f3a8cd123d4591d4f7 112 Gene3D G3DSA:3.40.250.10 23 97 2.6E-17 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS06205 68e6d3ebbb4ca2f3a8cd123d4591d4f7 112 SUPERFAMILY SSF52821 21 92 5.63E-17 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS06205 68e6d3ebbb4ca2f3a8cd123d4591d4f7 112 Pfam PF00581 Rhodanese-like domain 22 92 8.4E-9 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS06205 68e6d3ebbb4ca2f3a8cd123d4591d4f7 112 SMART SM00450 9 104 2.4E-5 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS16025 343cf33c7aa0ff64533f0fcf40d91802 104 PANTHER PTHR16821 1 103 1.9E-29 T 22-04-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 TOLA_RS16025 343cf33c7aa0ff64533f0fcf40d91802 104 Pfam PF01491 Frataxin-like domain 1 101 3.2E-27 T 22-04-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 TOLA_RS16025 343cf33c7aa0ff64533f0fcf40d91802 104 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 3 102 1.1E-40 T 22-04-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 TOLA_RS16025 343cf33c7aa0ff64533f0fcf40d91802 104 ProSitePatterns PS01344 Frataxin family signature. 48 62 - T 22-04-2016 IPR020895 Frataxin conserved site TOLA_RS16025 343cf33c7aa0ff64533f0fcf40d91802 104 Gene3D G3DSA:3.30.920.10 1 103 1.8E-31 T 22-04-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 TOLA_RS16025 343cf33c7aa0ff64533f0fcf40d91802 104 Hamap MF_00142 Protein CyaY [cyaY]. 1 103 27.276 T 22-04-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 TOLA_RS16025 343cf33c7aa0ff64533f0fcf40d91802 104 SUPERFAMILY SSF55387 1 103 1.55E-35 T 22-04-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 TOLA_RS16025 343cf33c7aa0ff64533f0fcf40d91802 104 SMART SM01219 1 104 6.0E-50 T 22-04-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 SUPERFAMILY SSF55681 99 464 1.68E-100 T 22-04-2016 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 421 435 3.6E-14 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 224 237 3.6E-14 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 220 3.6E-14 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 PRINTS PR01042 Aspartyl-tRNA synthetase signature 381 397 3.6E-14 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 PANTHER PTHR22594:SF6 8 180 6.3E-243 T 22-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 PANTHER PTHR22594:SF6 199 465 6.3E-243 T 22-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 PANTHER PTHR22594 8 180 6.3E-243 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 PANTHER PTHR22594 199 465 6.3E-243 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 Gene3D G3DSA:3.30.930.10 109 463 9.0E-117 T 22-04-2016 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 460 1.9E-84 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 SUPERFAMILY SSF50249 15 101 1.09E-14 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS05590 22c08e079828459558c8c044d622a205 466 Pfam PF01336 OB-fold nucleic acid binding domain 21 100 7.4E-9 T 22-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 466 46.092 T 22-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 TOLA_RS05590 22c08e079828459558c8c044d622a205 466 Gene3D G3DSA:2.40.50.140 15 102 2.8E-14 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS05590 22c08e079828459558c8c044d622a205 466 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 5 466 1.1E-204 T 22-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 TOLA_RS04845 37f278639188f39843cef9029db0e63d 542 Gene3D G3DSA:3.60.120.10 13 518 2.9E-155 T 22-04-2016 IPR005801 ADC synthase GO:0009058 TOLA_RS04845 37f278639188f39843cef9029db0e63d 542 Pfam PF00425 chorismate binding enzyme 246 506 3.0E-86 T 22-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal TOLA_RS04845 37f278639188f39843cef9029db0e63d 542 PANTHER PTHR11236:SF22 13 527 7.0E-230 T 22-04-2016 TOLA_RS04845 37f278639188f39843cef9029db0e63d 542 PANTHER PTHR11236 13 527 7.0E-230 T 22-04-2016 TOLA_RS04845 37f278639188f39843cef9029db0e63d 542 PIRSF PIRSF001373 1 525 2.0E-248 T 22-04-2016 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS04845 37f278639188f39843cef9029db0e63d 542 SUPERFAMILY SSF56322 12 518 4.97E-152 T 22-04-2016 IPR005801 ADC synthase GO:0009058 TOLA_RS04845 37f278639188f39843cef9029db0e63d 542 Pfam PF04715 Anthranilate synthase component I, N terminal region 21 194 8.6E-16 T 22-04-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS04845 37f278639188f39843cef9029db0e63d 542 PRINTS PR00095 Anthranilate synthase component I signature 354 367 3.4E-23 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS04845 37f278639188f39843cef9029db0e63d 542 PRINTS PR00095 Anthranilate synthase component I signature 448 462 3.4E-23 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS04845 37f278639188f39843cef9029db0e63d 542 PRINTS PR00095 Anthranilate synthase component I signature 368 381 3.4E-23 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS04845 37f278639188f39843cef9029db0e63d 542 PRINTS PR00095 Anthranilate synthase component I signature 463 477 3.4E-23 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS04845 37f278639188f39843cef9029db0e63d 542 TIGRFAM TIGR00565 trpE_proteo: anthranilate synthase component I 19 518 1.1E-214 T 22-04-2016 IPR005257 Anthranilate synthase component I, TrpE-like, bacterial GO:0004049|GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS06400 39f05904aeca1e9e56bdbb8cdac83519 231 Pfam PF04231 Endonuclease I 30 228 2.6E-44 T 22-04-2016 IPR007346 Endonuclease I GO:0004518 TOLA_RS06400 39f05904aeca1e9e56bdbb8cdac83519 231 SUPERFAMILY SSF54060 24 230 1.11E-87 T 22-04-2016 TOLA_RS06400 39f05904aeca1e9e56bdbb8cdac83519 231 PANTHER PTHR33607 27 226 1.2E-46 T 22-04-2016 TOLA_RS08580 75a73550227cdc121f8c5ceecf34032b 219 Pfam PF02288 Dehydratase medium subunit 64 176 1.0E-34 T 22-04-2016 IPR003208 Diol/glycerol dehydratase/dehydratase reactivating factor TOLA_RS08580 75a73550227cdc121f8c5ceecf34032b 219 Gene3D G3DSA:3.40.50.10150 42 218 8.3E-87 T 22-04-2016 IPR010254 B12-dependent dehydratases, beta subunit TOLA_RS08580 75a73550227cdc121f8c5ceecf34032b 219 PIRSF PIRSF018506 1 219 9.4E-110 T 22-04-2016 IPR025541 Propanediol/glycerol dehydratase, medium subunit KEGG: 00640+4.2.1.28|MetaCyc: PWY-7013|UniPathway: UPA00621 TOLA_RS08580 75a73550227cdc121f8c5ceecf34032b 219 SUPERFAMILY SSF52968 41 219 1.13E-72 T 22-04-2016 IPR010254 B12-dependent dehydratases, beta subunit TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 PANTHER PTHR10799 431 616 2.7E-42 T 22-04-2016 TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 PANTHER PTHR10799:SF774 431 616 2.7E-42 T 22-04-2016 TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 SMART SM00091 337 403 4.8E-10 T 22-04-2016 IPR000014 PAS domain TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 ProSitePatterns PS00550 Hemerythrin family signature. 686 709 - T 22-04-2016 IPR016131 Haemerythrin, iron-binding site GO:0046872 TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 Pfam PF01814 Hemerythrin HHE cation binding domain 641 751 9.1E-8 T 22-04-2016 IPR012312 Haemerythrin-like TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 SMART SM00267 445 618 1.1E-60 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 Gene3D G3DSA:3.30.450.20 338 453 5.8E-21 T 22-04-2016 TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 SUPERFAMILY SSF55073 461 617 5.3E-51 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 452 616 8.3E-46 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 635 755 5.7E-25 T 22-04-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 Gene3D G3DSA:3.30.450.20 89 183 3.3E-15 T 22-04-2016 TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 Pfam PF00990 Diguanylate cyclase, GGDEF domain 456 614 4.2E-48 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 SUPERFAMILY SSF47188 630 755 9.94E-25 T 22-04-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 Pfam PF08447 PAS fold 362 428 2.1E-9 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 Pfam PF02743 Cache domain 90 264 7.5E-18 T 22-04-2016 IPR033479 Double Cache domain 1 TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 SUPERFAMILY SSF55785 342 447 1.61E-19 T 22-04-2016 IPR000014 PAS domain TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 338 452 3.7E-16 T 22-04-2016 IPR000014 PAS domain TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 Gene3D G3DSA:1.20.120.50 635 755 7.3E-26 T 22-04-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 SUPERFAMILY SSF103190 56 183 7.59E-5 T 22-04-2016 IPR029151 Periplasmic sensor domain-like TOLA_RS16370 63d23cac877c5446acb8f290ca122e08 762 Gene3D G3DSA:3.30.70.270 457 618 9.6E-56 T 22-04-2016 TOLA_RS04960 d309ac0be527a80d8b4e8f446dc501a1 274 PANTHER PTHR11645 1 271 2.5E-101 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 TOLA_RS04960 d309ac0be527a80d8b4e8f446dc501a1 274 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 270 26.1 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 TOLA_RS04960 d309ac0be527a80d8b4e8f446dc501a1 274 PANTHER PTHR11645:SF0 1 271 2.5E-101 T 22-04-2016 TOLA_RS04960 d309ac0be527a80d8b4e8f446dc501a1 274 Gene3D G3DSA:3.40.50.720 2 162 1.1E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04960 d309ac0be527a80d8b4e8f446dc501a1 274 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 6 101 4.6E-21 T 22-04-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TOLA_RS04960 d309ac0be527a80d8b4e8f446dc501a1 274 SUPERFAMILY SSF51735 4 163 9.48E-41 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04960 d309ac0be527a80d8b4e8f446dc501a1 274 PIRSF PIRSF000193 3 272 9.9E-75 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 TOLA_RS04960 d309ac0be527a80d8b4e8f446dc501a1 274 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 270 1.7E-73 T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 TOLA_RS04960 d309ac0be527a80d8b4e8f446dc501a1 274 Gene3D G3DSA:1.10.3730.10 165 270 4.1E-30 T 22-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 TOLA_RS04960 d309ac0be527a80d8b4e8f446dc501a1 274 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 226 248 - T 22-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 TOLA_RS04960 d309ac0be527a80d8b4e8f446dc501a1 274 SUPERFAMILY SSF48179 164 271 3.74E-29 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS04960 d309ac0be527a80d8b4e8f446dc501a1 274 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 165 270 1.7E-30 T 22-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 SUPERFAMILY SSF55666 144 234 5.89E-28 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Pfam PF00575 S1 RNA binding domain 618 689 9.3E-21 T 22-04-2016 IPR003029 S1 domain GO:0003676 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Gene3D G3DSA:1.10.10.400 239 310 8.8E-22 T 22-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 SMART SM00322 551 616 3.5E-11 T 22-04-2016 IPR004087 K Homology domain GO:0003676 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 SUPERFAMILY SSF54211 4 143 8.1E-50 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Pfam PF03725 3' exoribonuclease family, domain 2 146 208 2.3E-11 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Pfam PF03725 3' exoribonuclease family, domain 2 459 527 5.4E-5 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 SUPERFAMILY SSF54791 553 621 3.26E-16 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 PANTHER PTHR11252:SF0 2 710 0.0 T 22-04-2016 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Pfam PF00013 KH domain 556 612 7.2E-9 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 690 0.0 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 SUPERFAMILY SSF54211 291 487 1.32E-46 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Pfam PF01138 3' exoribonuclease family, domain 1 15 143 2.4E-19 T 22-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Pfam PF01138 3' exoribonuclease family, domain 1 323 455 5.0E-22 T 22-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 2 692 30.241 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Gene3D G3DSA:3.30.1370.10 551 615 9.2E-25 T 22-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Gene3D G3DSA:3.30.230.70 311 540 6.1E-87 T 22-04-2016 IPR027408 PNPase/RNase PH domain TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Gene3D G3DSA:3.30.230.70 4 224 7.1E-82 T 22-04-2016 IPR027408 PNPase/RNase PH domain TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 PANTHER PTHR11252 2 710 0.0 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 241 319 3.7E-20 T 22-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 PIRSF PIRSF005499 1 719 2.0E-295 T 22-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 SUPERFAMILY SSF50249 605 691 3.26E-22 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 SMART SM00316 619 689 3.3E-26 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 Gene3D G3DSA:2.40.50.140 616 692 1.9E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS11380 8e7c38f84efeb298b6aaf5517d32456d 720 SUPERFAMILY SSF55666 449 547 4.64E-27 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 TOLA_RS13880 b1de3e426e06e881e525cbfb7220d397 292 PANTHER PTHR22777:SF17 15 292 8.4E-115 T 22-04-2016 TOLA_RS13880 b1de3e426e06e881e525cbfb7220d397 292 SMART SM00116 140 188 0.0078 T 22-04-2016 IPR000644 CBS domain TOLA_RS13880 b1de3e426e06e881e525cbfb7220d397 292 SMART SM00116 76 125 30.0 T 22-04-2016 IPR000644 CBS domain TOLA_RS13880 b1de3e426e06e881e525cbfb7220d397 292 Pfam PF03471 Transporter associated domain 208 282 1.1E-21 T 22-04-2016 IPR005170 Transporter-associated domain TOLA_RS13880 b1de3e426e06e881e525cbfb7220d397 292 SMART SM01091 206 284 5.0E-30 T 22-04-2016 IPR005170 Transporter-associated domain TOLA_RS13880 b1de3e426e06e881e525cbfb7220d397 292 Gene3D G3DSA:3.10.580.10 53 195 9.4E-23 T 22-04-2016 TOLA_RS13880 b1de3e426e06e881e525cbfb7220d397 292 SUPERFAMILY SSF56176 204 290 4.09E-24 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 TOLA_RS13880 b1de3e426e06e881e525cbfb7220d397 292 SUPERFAMILY SSF54631 56 198 8.72E-32 T 22-04-2016 TOLA_RS13880 b1de3e426e06e881e525cbfb7220d397 292 PANTHER PTHR22777 15 292 8.4E-115 T 22-04-2016 TOLA_RS13880 b1de3e426e06e881e525cbfb7220d397 292 Gene3D G3DSA:3.30.465.10 196 285 3.9E-28 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 TOLA_RS13880 b1de3e426e06e881e525cbfb7220d397 292 Pfam PF00571 CBS domain 67 121 7.1E-7 T 22-04-2016 IPR000644 CBS domain TOLA_RS13880 b1de3e426e06e881e525cbfb7220d397 292 Pfam PF00571 CBS domain 139 188 1.0E-5 T 22-04-2016 IPR000644 CBS domain TOLA_RS02340 cb1bcd2ac36d1481add8bafc293bfeb6 104 PANTHER PTHR34382 1 99 4.4E-42 T 22-04-2016 TOLA_RS02340 cb1bcd2ac36d1481add8bafc293bfeb6 104 SUPERFAMILY SSF46973 1 98 9.55E-35 T 22-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS02340 cb1bcd2ac36d1481add8bafc293bfeb6 104 PANTHER PTHR34382:SF2 1 99 4.4E-42 T 22-04-2016 TOLA_RS02340 cb1bcd2ac36d1481add8bafc293bfeb6 104 Gene3D G3DSA:1.20.58.80 2 99 4.3E-39 T 22-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS02340 cb1bcd2ac36d1481add8bafc293bfeb6 104 PIRSF PIRSF000699 1 103 3.3E-36 T 22-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS02340 cb1bcd2ac36d1481add8bafc293bfeb6 104 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 6 98 3.7E-34 T 22-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 Pfam PF13375 RnfC Barrel sandwich hybrid domain 9 93 4.8E-24 T 22-04-2016 IPR026902 RnfC Barrel sandwich hybrid domain TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 483 131.671 T 22-04-2016 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 Gene3D G3DSA:1.10.1060.10 310 430 3.5E-14 T 22-04-2016 TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 9 428 4.3E-152 T 22-04-2016 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 SUPERFAMILY SSF142019 99 287 1.01E-52 T 22-04-2016 TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 PANTHER PTHR11780 10 465 3.1E-154 T 22-04-2016 TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 SUPERFAMILY SSF46548 316 425 2.62E-17 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 PANTHER PTHR11780:SF1 10 465 3.1E-154 T 22-04-2016 TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 Pfam PF13237 4Fe-4S dicluster domain 357 410 2.2E-8 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 122 267 1.0E-47 T 22-04-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 Pfam PF10531 SLBB domain 280 328 5.0E-11 T 22-04-2016 IPR019554 Soluble ligand binding domain TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 360 371 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS11855 7493fbd4cf8a8647b7e8355625b42efa 483 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 399 410 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS04335 5eac352b70bbdc9aaaa52169f1e25c4c 190 PANTHER PTHR38104 1 186 1.2E-34 T 22-04-2016 TOLA_RS04335 5eac352b70bbdc9aaaa52169f1e25c4c 190 SUPERFAMILY SSF89069 4 68 8.89E-18 T 22-04-2016 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 TOLA_RS04335 5eac352b70bbdc9aaaa52169f1e25c4c 190 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 5 76 1.1E-21 T 22-04-2016 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 TOLA_RS04335 5eac352b70bbdc9aaaa52169f1e25c4c 190 Pfam PF03873 Anti sigma-E protein RseA, C-terminal domain 124 185 1.8E-20 T 22-04-2016 IPR005573 Anti sigma-E protein RseA, C-terminal TOLA_RS04335 5eac352b70bbdc9aaaa52169f1e25c4c 190 PIRSF PIRSF016938 1 190 2.3E-36 T 22-04-2016 IPR026279 Sigma-E factor negative regulatory protein RseA GO:0006950|GO:0016989 TOLA_RS09550 a4f4936e3b3a0c58189cf563b9252d18 75 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 2 42 5.9E-8 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS09550 a4f4936e3b3a0c58189cf563b9252d18 75 PANTHER PTHR11493:SF47 1 75 2.0E-18 T 22-04-2016 TOLA_RS09550 a4f4936e3b3a0c58189cf563b9252d18 75 Gene3D G3DSA:3.90.480.10 1 47 2.4E-11 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS09550 a4f4936e3b3a0c58189cf563b9252d18 75 SUPERFAMILY SSF55124 2 47 3.27E-9 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS09550 a4f4936e3b3a0c58189cf563b9252d18 75 PANTHER PTHR11493 1 75 2.0E-18 T 22-04-2016 TOLA_RS12590 70979238561482f0556f018ffa76b2b2 565 PANTHER PTHR36837 14 565 5.7E-207 T 22-04-2016 TOLA_RS12590 70979238561482f0556f018ffa76b2b2 565 SUPERFAMILY SSF53474 189 488 5.28E-41 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS12590 70979238561482f0556f018ffa76b2b2 565 Pfam PF12551 Poly-beta-hydroxybutyrate polymerase N terminal 2 36 4.6E-12 T 22-04-2016 IPR022211 Poly-beta-hydroxybutyrate polymerase N-terminal TOLA_RS12590 70979238561482f0556f018ffa76b2b2 565 PANTHER PTHR36837:SF2 14 565 5.7E-207 T 22-04-2016 TOLA_RS12590 70979238561482f0556f018ffa76b2b2 565 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 75 244 9.2E-58 T 22-04-2016 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.- TOLA_RS12590 70979238561482f0556f018ffa76b2b2 565 Gene3D G3DSA:3.40.50.1820 181 536 2.0E-30 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS00385 68821b4d16acdb7e2e8a8312f7b478be 677 SUPERFAMILY SSF69255 380 468 1.65E-33 T 22-04-2016 TOLA_RS00385 68821b4d16acdb7e2e8a8312f7b478be 677 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 12 537 2.8E-167 T 22-04-2016 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset TOLA_RS00385 68821b4d16acdb7e2e8a8312f7b478be 677 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 21 520 1.7E-105 T 22-04-2016 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein TOLA_RS00385 68821b4d16acdb7e2e8a8312f7b478be 677 PANTHER PTHR32305:SF11 1 640 1.8E-148 T 22-04-2016 TOLA_RS00385 68821b4d16acdb7e2e8a8312f7b478be 677 PANTHER PTHR32305 1 640 1.8E-148 T 22-04-2016 TOLA_RS00385 68821b4d16acdb7e2e8a8312f7b478be 677 Gene3D G3DSA:2.40.50.230 387 468 6.3E-39 T 22-04-2016 IPR006531 Gp5 N-terminal TOLA_RS00385 68821b4d16acdb7e2e8a8312f7b478be 677 SUPERFAMILY SSF69279 190 376 1.55E-16 T 22-04-2016 TOLA_RS00385 68821b4d16acdb7e2e8a8312f7b478be 677 SUPERFAMILY SSF69279 11 186 5.95E-50 T 22-04-2016 TOLA_RS00385 68821b4d16acdb7e2e8a8312f7b478be 677 Gene3D G3DSA:3.55.50.10 97 190 6.1E-31 T 22-04-2016 TOLA_RS00385 68821b4d16acdb7e2e8a8312f7b478be 677 Pfam PF05954 Phage late control gene D protein (GPD) 30 346 1.7E-59 T 22-04-2016 TOLA_RS00385 68821b4d16acdb7e2e8a8312f7b478be 677 SUPERFAMILY SSF69349 458 641 3.77E-39 T 22-04-2016 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 ProSitePatterns PS01135 FtsZ protein signature 2. 99 120 - T 22-04-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 PANTHER PTHR30314:SF3 12 384 1.2E-200 T 22-04-2016 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 Gene3D G3DSA:3.40.50.1440 16 216 5.6E-95 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 PRINTS PR00423 Cell division protein FtsZ signature 100 120 2.5E-52 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 PRINTS PR00423 Cell division protein FtsZ signature 214 235 2.5E-52 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 PRINTS PR00423 Cell division protein FtsZ signature 128 149 2.5E-52 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 PRINTS PR00423 Cell division protein FtsZ signature 191 213 2.5E-52 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 SMART SM00865 209 327 2.0E-56 T 22-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 SUPERFAMILY SSF52490 16 210 3.53E-70 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 Pfam PF12327 FtsZ family, C-terminal domain 224 318 1.2E-36 T 22-04-2016 IPR024757 Cell division protein FtsZ, C-terminal TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 11 349 38.302 T 22-04-2016 IPR000158 Cell division protein FtsZ GO:0005525 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 338 1.1E-137 T 22-04-2016 IPR000158 Cell division protein FtsZ GO:0005525 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 175 1.3E-42 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 PANTHER PTHR30314 12 384 1.2E-200 T 22-04-2016 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 ProSitePatterns PS01134 FtsZ protein signature 1. 46 80 - T 22-04-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 Gene3D G3DSA:3.30.1330.20 217 323 1.0E-47 T 22-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 SUPERFAMILY SSF55307 206 322 3.89E-43 T 22-04-2016 IPR008280 Tubulin/FtsZ, C-terminal TOLA_RS02740 386698ca123c6871f0b86130ec49987b 386 SMART SM00864 15 207 5.5E-115 T 22-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 Gene3D G3DSA:2.10.230.10 138 207 6.6E-26 T 22-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 SUPERFAMILY SSF49493 111 166 1.57E-21 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 SUPERFAMILY SSF49493 210 264 1.57E-21 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 SMART SM00271 4 62 1.4E-31 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 370 42.316 T 22-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 Gene3D G3DSA:2.60.260.20 105 137 1.8E-22 T 22-04-2016 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 Gene3D G3DSA:2.60.260.20 208 251 1.8E-22 T 22-04-2016 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 346 8.8E-140 T 22-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 Gene3D G3DSA:1.10.287.110 1 102 3.4E-37 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 Pfam PF01556 DnaJ C terminal domain 118 330 1.1E-44 T 22-04-2016 IPR002939 Chaperone DnaJ, C-terminal TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 PRINTS PR00625 DnaJ domain signature 7 25 3.7E-31 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 PRINTS PR00625 DnaJ domain signature 62 81 3.7E-31 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 PRINTS PR00625 DnaJ domain signature 42 62 3.7E-31 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 PRINTS PR00625 DnaJ domain signature 25 40 3.7E-31 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 PANTHER PTHR24078 1 347 6.8E-171 T 22-04-2016 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 Gene3D G3DSA:2.60.260.20 253 330 1.2E-20 T 22-04-2016 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 Pfam PF00684 DnaJ central domain 144 204 2.7E-15 T 22-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 Pfam PF00226 DnaJ domain 5 67 1.3E-27 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 SUPERFAMILY SSF49493 256 341 1.7E-20 T 22-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 SUPERFAMILY SSF57938 131 208 7.19E-23 T 22-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 PANTHER PTHR24078:SF231 1 347 6.8E-171 T 22-04-2016 TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 22-04-2016 IPR018253 DnaJ domain, conserved site TOLA_RS11460 b5c1c793c73031a262c3e0ad71866476 376 SUPERFAMILY SSF46565 1 105 2.75E-36 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS12125 d3ba2155e02b2dc2329776ed4b8bca8f 85 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 5 64 9.1E-30 T 22-04-2016 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 TOLA_RS12125 d3ba2155e02b2dc2329776ed4b8bca8f 85 Gene3D G3DSA:2.30.30.100 1 70 1.4E-37 T 22-04-2016 TOLA_RS12125 d3ba2155e02b2dc2329776ed4b8bca8f 85 PANTHER PTHR34772:SF1 1 85 1.0E-41 T 22-04-2016 TOLA_RS12125 d3ba2155e02b2dc2329776ed4b8bca8f 85 PANTHER PTHR34772 1 85 1.0E-41 T 22-04-2016 TOLA_RS12125 d3ba2155e02b2dc2329776ed4b8bca8f 85 SUPERFAMILY SSF50182 7 68 2.84E-24 T 22-04-2016 IPR010920 LSM domain TOLA_RS12125 d3ba2155e02b2dc2329776ed4b8bca8f 85 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 3 64 27.396 T 22-04-2016 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 TOLA_RS02475 6f1439f1ec88edb445ce0966678d9fc8 294 Gene3D G3DSA:3.60.110.10 4 286 2.3E-94 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS02475 6f1439f1ec88edb445ce0966678d9fc8 294 PANTHER PTHR23088 1 288 1.3E-150 T 22-04-2016 TOLA_RS02475 6f1439f1ec88edb445ce0966678d9fc8 294 TIGRFAM TIGR03381 agmatine_aguB: N-carbamoylputrescine amidase 4 285 8.0E-143 T 22-04-2016 IPR017755 N-carbamoylputrescine amidase GO:0006596|GO:0050126 KEGG: 00330+3.5.1.53|MetaCyc: PWY-43|UniPathway: UPA00534 TOLA_RS02475 6f1439f1ec88edb445ce0966678d9fc8 294 SUPERFAMILY SSF56317 1 285 3.79E-83 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS02475 6f1439f1ec88edb445ce0966678d9fc8 294 Pfam PF00795 Carbon-nitrogen hydrolase 5 267 4.8E-54 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS02475 6f1439f1ec88edb445ce0966678d9fc8 294 PANTHER PTHR23088:SF11 1 288 1.3E-150 T 22-04-2016 TOLA_RS10260 2eb47e77c9285226d743c18a7eed05aa 128 Pfam PF01592 NifU-like N terminal domain 2 125 4.8E-57 T 22-04-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 TOLA_RS10260 2eb47e77c9285226d743c18a7eed05aa 128 PANTHER PTHR10093:SF3 1 127 2.3E-99 T 22-04-2016 TOLA_RS10260 2eb47e77c9285226d743c18a7eed05aa 128 Gene3D G3DSA:3.90.1010.10 2 125 4.5E-57 T 22-04-2016 TOLA_RS10260 2eb47e77c9285226d743c18a7eed05aa 128 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 5.1E-69 T 22-04-2016 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 TOLA_RS10260 2eb47e77c9285226d743c18a7eed05aa 128 SUPERFAMILY SSF82649 1 125 3.66E-50 T 22-04-2016 TOLA_RS10260 2eb47e77c9285226d743c18a7eed05aa 128 PANTHER PTHR10093 1 127 2.3E-99 T 22-04-2016 TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 SUPERFAMILY SSF81296 113 223 2.45E-24 T 22-04-2016 IPR014756 Immunoglobulin E-set TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 PANTHER PTHR10357:SF158 44 724 0.0 T 22-04-2016 TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 SMART SM00642 247 591 5.6E-7 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 Gene3D G3DSA:3.20.20.80 242 608 1.2E-87 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 Pfam PF00128 Alpha amylase, catalytic domain 272 343 1.1E-7 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 PIRSF PIRSF000463 2 727 3.0E-270 T 22-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 SUPERFAMILY SSF81296 11 99 9.8E-12 T 22-04-2016 IPR014756 Immunoglobulin E-set TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 91 725 41.591 T 22-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 Gene3D G3DSA:2.60.40.1180 621 723 7.3E-26 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 SUPERFAMILY SSF51445 242 617 1.12E-108 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 Gene3D G3DSA:2.60.40.10 6 97 2.0E-12 T 22-04-2016 IPR013783 Immunoglobulin-like fold TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 Gene3D G3DSA:2.60.40.10 113 219 2.4E-27 T 22-04-2016 IPR013783 Immunoglobulin-like fold TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 118 202 1.3E-16 T 22-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 625 724 5.1E-15 T 22-04-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: REACT_474 TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 PANTHER PTHR10357 44 724 0.0 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 SUPERFAMILY SSF51011 621 724 3.88E-24 T 22-04-2016 TOLA_RS13720 6639975cefc13f8794179a15e6871bb2 727 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 112 722 4.2E-256 T 22-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS11940 5bbf0c912d7cd5b76747b7751ba33d96 220 Gene3D G3DSA:1.10.150.240 19 58 5.0E-6 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 TOLA_RS11940 5bbf0c912d7cd5b76747b7751ba33d96 220 Gene3D G3DSA:3.40.50.1000 64 212 8.2E-47 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS11940 5bbf0c912d7cd5b76747b7751ba33d96 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 181 1.3E-26 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS11940 5bbf0c912d7cd5b76747b7751ba33d96 220 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 54 181 6.5E-16 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS11940 5bbf0c912d7cd5b76747b7751ba33d96 220 PANTHER PTHR18901 1 217 1.9E-119 T 22-04-2016 TOLA_RS11940 5bbf0c912d7cd5b76747b7751ba33d96 220 PANTHER PTHR18901:SF20 1 217 1.9E-119 T 22-04-2016 TOLA_RS11940 5bbf0c912d7cd5b76747b7751ba33d96 220 SUPERFAMILY SSF56784 3 203 7.46E-45 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS11940 5bbf0c912d7cd5b76747b7751ba33d96 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 163 4.2E-7 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS11940 5bbf0c912d7cd5b76747b7751ba33d96 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 95 108 4.2E-7 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS11940 5bbf0c912d7cd5b76747b7751ba33d96 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 4.2E-7 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS11940 5bbf0c912d7cd5b76747b7751ba33d96 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 141 4.2E-7 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS10400 657eab6cc53a209066b6f2f27532c5ff 370 PANTHER PTHR41244 3 367 9.2E-96 T 22-04-2016 TOLA_RS10400 657eab6cc53a209066b6f2f27532c5ff 370 Pfam PF14307 Glycosyltransferase WbsX 4 361 1.8E-135 T 22-04-2016 IPR032719 Glycosyltransferase WbsX TOLA_RS10400 657eab6cc53a209066b6f2f27532c5ff 370 PANTHER PTHR41244:SF1 3 367 9.2E-96 T 22-04-2016 TOLA_RS00515 c8000855ba156733468f3259ae764120 103 SMART SM01403 7 101 9.2E-57 T 22-04-2016 IPR027486 Ribosomal protein S10 domain TOLA_RS00515 c8000855ba156733468f3259ae764120 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 22-04-2016 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00515 c8000855ba156733468f3259ae764120 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.2E-18 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00515 c8000855ba156733468f3259ae764120 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.2E-18 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00515 c8000855ba156733468f3259ae764120 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.2E-18 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00515 c8000855ba156733468f3259ae764120 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.412 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00515 c8000855ba156733468f3259ae764120 103 PANTHER PTHR11700 1 102 1.8E-55 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00515 c8000855ba156733468f3259ae764120 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 1.3E-46 T 22-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00515 c8000855ba156733468f3259ae764120 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 2.8E-35 T 22-04-2016 IPR027486 Ribosomal protein S10 domain TOLA_RS00515 c8000855ba156733468f3259ae764120 103 Gene3D G3DSA:3.30.70.600 3 102 1.0E-43 T 22-04-2016 IPR027486 Ribosomal protein S10 domain TOLA_RS00515 c8000855ba156733468f3259ae764120 103 SUPERFAMILY SSF54999 5 101 1.23E-36 T 22-04-2016 IPR027486 Ribosomal protein S10 domain TOLA_RS08590 f560b1974f6ea6fe35ae3782fb8fa17a 608 SUPERFAMILY SSF82317 93 254 2.88E-68 T 22-04-2016 IPR028975 Diol dehydratase-reactivating factor, alpha subunit, swiveling domain TOLA_RS08590 f560b1974f6ea6fe35ae3782fb8fa17a 608 Pfam PF08841 Diol dehydratase reactivase ATPase-like domain 275 602 1.2E-162 T 22-04-2016 IPR030994 Diol dehydratase reactivase ATPase-like domain TOLA_RS08590 f560b1974f6ea6fe35ae3782fb8fa17a 608 Gene3D G3DSA:3.50.30.70 97 247 1.0E-71 T 22-04-2016 IPR028975 Diol dehydratase-reactivating factor, alpha subunit, swiveling domain TOLA_RS08590 f560b1974f6ea6fe35ae3782fb8fa17a 608 TIGRFAM TIGR04491 reactive_PduG: diol dehydratase reactivase alpha subunit 3 601 2.8E-290 T 22-04-2016 IPR009191 Diol dehydratase-reactivating factor alpha subunit TOLA_RS08590 f560b1974f6ea6fe35ae3782fb8fa17a 608 SUPERFAMILY SSF53067 255 403 5.5E-71 T 22-04-2016 TOLA_RS08590 f560b1974f6ea6fe35ae3782fb8fa17a 608 SUPERFAMILY SSF53067 3 93 5.5E-71 T 22-04-2016 TOLA_RS08590 f560b1974f6ea6fe35ae3782fb8fa17a 608 Gene3D G3DSA:3.30.420.40 471 604 1.4E-35 T 22-04-2016 TOLA_RS08590 f560b1974f6ea6fe35ae3782fb8fa17a 608 Gene3D G3DSA:3.30.420.40 298 444 4.1E-38 T 22-04-2016 TOLA_RS08590 f560b1974f6ea6fe35ae3782fb8fa17a 608 PIRSF PIRSF011502 1 607 0.0 T 22-04-2016 IPR009191 Diol dehydratase-reactivating factor alpha subunit TOLA_RS08590 f560b1974f6ea6fe35ae3782fb8fa17a 608 SUPERFAMILY SSF53067 407 600 2.59E-34 T 22-04-2016 TOLA_RS08180 5ca0fdb0fb335054ebaefe9560517b6a 513 PANTHER PTHR35004 6 458 1.1E-104 T 22-04-2016 TOLA_RS08180 5ca0fdb0fb335054ebaefe9560517b6a 513 PANTHER PTHR35004:SF2 6 458 1.1E-104 T 22-04-2016 TOLA_RS08180 5ca0fdb0fb335054ebaefe9560517b6a 513 Gene3D G3DSA:3.30.420.10 139 304 4.6E-10 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS08180 5ca0fdb0fb335054ebaefe9560517b6a 513 Pfam PF00665 Integrase core domain 138 269 5.7E-19 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 TOLA_RS08180 5ca0fdb0fb335054ebaefe9560517b6a 513 SUPERFAMILY SSF53098 141 303 3.79E-9 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS00375 7f6de216567717c5eb0f606202c61ab5 317 SMART SM00829 10 310 7.2E-26 T 22-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TOLA_RS00375 7f6de216567717c5eb0f606202c61ab5 317 Pfam PF13602 Zinc-binding dehydrogenase 187 310 8.0E-25 T 22-04-2016 TOLA_RS00375 7f6de216567717c5eb0f606202c61ab5 317 SUPERFAMILY SSF51735 117 287 9.76E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00375 7f6de216567717c5eb0f606202c61ab5 317 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 145 166 - T 22-04-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TOLA_RS00375 7f6de216567717c5eb0f606202c61ab5 317 PANTHER PTHR11695 15 314 4.3E-92 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 TOLA_RS00375 7f6de216567717c5eb0f606202c61ab5 317 SUPERFAMILY SSF50129 3 150 6.24E-34 T 22-04-2016 IPR011032 GroES-like TOLA_RS00375 7f6de216567717c5eb0f606202c61ab5 317 Gene3D G3DSA:3.90.180.10 1 151 5.2E-43 T 22-04-2016 IPR011032 GroES-like TOLA_RS00375 7f6de216567717c5eb0f606202c61ab5 317 Gene3D G3DSA:3.40.50.720 152 236 6.5E-20 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00375 7f6de216567717c5eb0f606202c61ab5 317 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 1.4E-6 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PIRSF PIRSF002869 1 520 4.9E-146 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 Pfam PF03023 MviN-like protein 30 478 6.5E-139 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PANTHER PTHR11206:SF90 481 505 1.5E-81 T 22-04-2016 TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 4 505 8.7E-127 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PANTHER PTHR11206 226 451 1.5E-81 T 22-04-2016 TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PANTHER PTHR11206 481 505 1.5E-81 T 22-04-2016 TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PANTHER PTHR11206 69 84 1.5E-81 T 22-04-2016 TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PANTHER PTHR11206:SF90 69 84 1.5E-81 T 22-04-2016 TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PRINTS PR01806 Virulence factor MviN signature 366 385 4.3E-69 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PRINTS PR01806 Virulence factor MviN signature 418 435 4.3E-69 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PRINTS PR01806 Virulence factor MviN signature 166 187 4.3E-69 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PRINTS PR01806 Virulence factor MviN signature 268 294 4.3E-69 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PRINTS PR01806 Virulence factor MviN signature 35 54 4.3E-69 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PRINTS PR01806 Virulence factor MviN signature 54 70 4.3E-69 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PRINTS PR01806 Virulence factor MviN signature 142 166 4.3E-69 T 22-04-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TOLA_RS15160 8e622e46a953a5f10598f5f5ea55d90e 521 PANTHER PTHR11206:SF90 226 451 1.5E-81 T 22-04-2016 TOLA_RS00550 5d9410f67046cf40c54aaaaad11233a5 238 Pfam PF07650 KH domain 39 111 2.8E-18 T 22-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 TOLA_RS00550 5d9410f67046cf40c54aaaaad11233a5 238 PANTHER PTHR11760:SF19 2 236 1.4E-147 T 22-04-2016 TOLA_RS00550 5d9410f67046cf40c54aaaaad11233a5 238 SUPERFAMILY SSF54821 108 206 6.54E-41 T 22-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 TOLA_RS00550 5d9410f67046cf40c54aaaaad11233a5 238 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 2.0E-99 T 22-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TOLA_RS00550 5d9410f67046cf40c54aaaaad11233a5 238 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 5.4E-42 T 22-04-2016 TOLA_RS00550 5d9410f67046cf40c54aaaaad11233a5 238 PANTHER PTHR11760 2 236 1.4E-147 T 22-04-2016 TOLA_RS00550 5d9410f67046cf40c54aaaaad11233a5 238 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.928 T 22-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TOLA_RS00550 5d9410f67046cf40c54aaaaad11233a5 238 SUPERFAMILY SSF54814 2 106 9.16E-37 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 TOLA_RS00550 5d9410f67046cf40c54aaaaad11233a5 238 Gene3D G3DSA:3.30.300.20 18 107 1.5E-32 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta TOLA_RS00550 5d9410f67046cf40c54aaaaad11233a5 238 Gene3D G3DSA:3.30.1140.32 108 207 3.0E-48 T 22-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 TOLA_RS00550 5d9410f67046cf40c54aaaaad11233a5 238 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 22-04-2016 IPR018280 Ribosomal protein S3, conserved site TOLA_RS00550 5d9410f67046cf40c54aaaaad11233a5 238 SMART SM00322 60 125 2.4E-7 T 22-04-2016 IPR004087 K Homology domain GO:0003676 TOLA_RS04695 5c528ba18fee0a64d66164bce17f636f 265 PANTHER PTHR11907:SF10 1 254 6.8E-119 T 22-04-2016 TOLA_RS04695 5c528ba18fee0a64d66164bce17f636f 265 Gene3D G3DSA:3.60.20.10 2 252 3.7E-63 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS04695 5c528ba18fee0a64d66164bce17f636f 265 PANTHER PTHR11907 1 254 6.8E-119 T 22-04-2016 TOLA_RS04695 5c528ba18fee0a64d66164bce17f636f 265 Pfam PF13230 Glutamine amidotransferases class-II 2 261 1.0E-113 T 22-04-2016 IPR026869 Putative glutamine amidotransferase type 2 TOLA_RS04695 5c528ba18fee0a64d66164bce17f636f 265 SUPERFAMILY SSF56235 2 253 2.51E-48 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 Pfam PF01926 50S ribosome-binding GTPase 200 318 1.1E-21 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 Pfam PF16360 GTP-binding GTPase Middle Region 114 192 2.9E-29 T 22-04-2016 IPR032305 GTP-binding protein, middle domain TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 360 1.4E-152 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 Pfam PF13167 GTP-binding GTPase N-terminal 25 112 1.3E-31 T 22-04-2016 IPR025121 GTPase HflX, N-terminal TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 SUPERFAMILY SSF52540 198 362 1.84E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 SUPERFAMILY SSF54980 365 420 3.38E-10 T 22-04-2016 IPR009022 Elongation factor G, III-V domain TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 Hamap MF_00900 GTPase HflX [hflX]. 27 390 46.187 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 PANTHER PTHR10229:SF0 1 429 4.2E-179 T 22-04-2016 TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 PANTHER PTHR10229 1 429 4.2E-179 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 PIRSF PIRSF006809 4 418 9.8E-145 T 22-04-2016 IPR016496 GTPase HflX GO:0005525 TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 Gene3D G3DSA:3.40.50.300 198 361 2.7E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 200 220 1.4E-9 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 267 285 1.4E-9 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS12120 f520a29ead0f0649d70d467c69b01fde 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 221 239 1.4E-9 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS01040 f338d540380dc1579a6f5aa7e501b8f0 93 Hamap MF_01537 UPF0345 protein YaiE [yaiE]. 1 93 26.899 T 22-04-2016 IPR009664 Protein of unknown function DUF1255 TOLA_RS01040 f338d540380dc1579a6f5aa7e501b8f0 93 Pfam PF06865 Protein of unknown function (DUF1255) 3 92 1.9E-37 T 22-04-2016 IPR009664 Protein of unknown function DUF1255 TOLA_RS01040 f338d540380dc1579a6f5aa7e501b8f0 93 PANTHER PTHR36540:SF1 1 93 4.4E-46 T 22-04-2016 TOLA_RS01040 f338d540380dc1579a6f5aa7e501b8f0 93 PANTHER PTHR36540 1 93 4.4E-46 T 22-04-2016 TOLA_RS01040 f338d540380dc1579a6f5aa7e501b8f0 93 SUPERFAMILY SSF51182 1 92 5.35E-37 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS01040 f338d540380dc1579a6f5aa7e501b8f0 93 Gene3D G3DSA:2.60.120.10 1 93 1.4E-39 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS03510 6165cb81eb72ed3a77df71647b78809f 521 Pfam PF00682 HMGL-like 4 273 1.2E-100 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 TOLA_RS03510 6165cb81eb72ed3a77df71647b78809f 521 SMART SM00917 369 500 2.1E-36 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 TOLA_RS03510 6165cb81eb72ed3a77df71647b78809f 521 SUPERFAMILY SSF51569 1 291 3.3E-98 T 22-04-2016 TOLA_RS03510 6165cb81eb72ed3a77df71647b78809f 521 SUPERFAMILY SSF110921 391 499 6.41E-25 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 TOLA_RS03510 6165cb81eb72ed3a77df71647b78809f 521 PANTHER PTHR10277 1 508 2.5E-253 T 22-04-2016 TOLA_RS03510 6165cb81eb72ed3a77df71647b78809f 521 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 497 2.7E-244 T 22-04-2016 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 TOLA_RS03510 6165cb81eb72ed3a77df71647b78809f 521 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 509 43.004 T 22-04-2016 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 TOLA_RS03510 6165cb81eb72ed3a77df71647b78809f 521 PANTHER PTHR10277:SF9 1 508 2.5E-253 T 22-04-2016 TOLA_RS03510 6165cb81eb72ed3a77df71647b78809f 521 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 TOLA_RS03510 6165cb81eb72ed3a77df71647b78809f 521 Gene3D G3DSA:3.20.20.70 1 346 9.9E-144 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS03510 6165cb81eb72ed3a77df71647b78809f 521 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 TOLA_RS03510 6165cb81eb72ed3a77df71647b78809f 521 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 499 7.5E-35 T 22-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 TOLA_RS12130 c42da719f0a4965318aee6e11e4c6a13 298 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 1 282 7.7E-113 T 22-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 TOLA_RS12130 c42da719f0a4965318aee6e11e4c6a13 298 PANTHER PTHR11088 1 287 1.8E-119 T 22-04-2016 TOLA_RS12130 c42da719f0a4965318aee6e11e4c6a13 298 Pfam PF01715 IPP transferase 31 276 4.4E-86 T 22-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 TOLA_RS12130 c42da719f0a4965318aee6e11e4c6a13 298 Gene3D G3DSA:3.40.50.300 1 163 3.8E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12130 c42da719f0a4965318aee6e11e4c6a13 298 Gene3D G3DSA:1.10.287.890 192 274 1.8E-33 T 22-04-2016 TOLA_RS12130 c42da719f0a4965318aee6e11e4c6a13 298 SUPERFAMILY SSF52540 1 142 2.7E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12130 c42da719f0a4965318aee6e11e4c6a13 298 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 1 293 27.698 T 22-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 TOLA_RS10815 6c8fc337733badce65a2f6c9d673cc4e 315 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 301 3.6E-151 T 22-04-2016 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46|UniPathway: UPA00051 TOLA_RS10815 6c8fc337733badce65a2f6c9d673cc4e 315 SUPERFAMILY SSF52317 17 297 2.34E-101 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS10815 6c8fc337733badce65a2f6c9d673cc4e 315 Pfam PF04204 Homoserine O-succinyltransferase 2 299 4.2E-133 T 22-04-2016 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46|UniPathway: UPA00051 TOLA_RS10815 6c8fc337733badce65a2f6c9d673cc4e 315 PANTHER PTHR20919 2 313 3.7E-150 T 22-04-2016 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46|UniPathway: UPA00051 TOLA_RS10815 6c8fc337733badce65a2f6c9d673cc4e 315 PIRSF PIRSF000450 1 309 4.2E-145 T 22-04-2016 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46|UniPathway: UPA00051 TOLA_RS10815 6c8fc337733badce65a2f6c9d673cc4e 315 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 6.0E-100 T 22-04-2016 TOLA_RS10815 6c8fc337733badce65a2f6c9d673cc4e 315 PANTHER PTHR20919:SF0 2 313 3.7E-150 T 22-04-2016 TOLA_RS10815 6c8fc337733badce65a2f6c9d673cc4e 315 Gene3D G3DSA:3.40.50.880 34 301 1.3E-118 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS10815 6c8fc337733badce65a2f6c9d673cc4e 315 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 52.492 T 22-04-2016 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46|UniPathway: UPA00051 TOLA_RS13155 5af6b91cf646e30c447f27809f2046b3 279 Gene3D G3DSA:3.20.20.70 134 267 2.4E-60 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS13155 5af6b91cf646e30c447f27809f2046b3 279 SUPERFAMILY SSF54675 1 112 2.16E-32 T 22-04-2016 TOLA_RS13155 5af6b91cf646e30c447f27809f2046b3 279 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 116 277 4.4E-56 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 TOLA_RS13155 5af6b91cf646e30c447f27809f2046b3 279 PANTHER PTHR32179 1 279 2.4E-125 T 22-04-2016 TOLA_RS13155 5af6b91cf646e30c447f27809f2046b3 279 PIRSF PIRSF006250 1 279 1.1E-99 T 22-04-2016 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD TOLA_RS13155 5af6b91cf646e30c447f27809f2046b3 279 Gene3D G3DSA:3.90.1170.20 1 133 2.3E-49 T 22-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 TOLA_RS13155 5af6b91cf646e30c447f27809f2046b3 279 SUPERFAMILY SSF51690 114 278 2.79E-58 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 TOLA_RS13155 5af6b91cf646e30c447f27809f2046b3 279 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 278 2.6E-94 T 22-04-2016 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|UniPathway: UPA00253 TOLA_RS13155 5af6b91cf646e30c447f27809f2046b3 279 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 26 111 4.1E-25 T 22-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 TOLA_RS16190 fa0ce5c14545ba6722f167f7745cd36c 317 Pfam PF00923 Transaldolase 13 312 3.6E-98 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS16190 fa0ce5c14545ba6722f167f7745cd36c 317 PANTHER PTHR10683 1 315 9.3E-179 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS16190 fa0ce5c14545ba6722f167f7745cd36c 317 Gene3D G3DSA:3.20.20.70 1 315 2.3E-126 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS16190 fa0ce5c14545ba6722f167f7745cd36c 317 ProSitePatterns PS01054 Transaldolase signature 1. 30 38 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS16190 fa0ce5c14545ba6722f167f7745cd36c 317 Hamap MF_00492 Transaldolase [tal]. 1 317 50.583 T 22-04-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS16190 fa0ce5c14545ba6722f167f7745cd36c 317 TIGRFAM TIGR00874 talAB: transaldolase 2 316 3.6E-153 T 22-04-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS16190 fa0ce5c14545ba6722f167f7745cd36c 317 SUPERFAMILY SSF51569 1 315 3.56E-110 T 22-04-2016 TOLA_RS16190 fa0ce5c14545ba6722f167f7745cd36c 317 PANTHER PTHR10683:SF16 1 315 9.3E-179 T 22-04-2016 TOLA_RS16190 fa0ce5c14545ba6722f167f7745cd36c 317 ProSitePatterns PS00958 Transaldolase active site. 128 145 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS02510 f5a7c957871bb9f7f391714d4d7130ed 335 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 321 1.9E-128 T 22-04-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TOLA_RS02510 f5a7c957871bb9f7f391714d4d7130ed 335 SUPERFAMILY SSF56655 2 324 1.02E-104 T 22-04-2016 TOLA_RS02510 f5a7c957871bb9f7f391714d4d7130ed 335 Gene3D G3DSA:3.30.540.10 170 329 5.6E-47 T 22-04-2016 TOLA_RS02510 f5a7c957871bb9f7f391714d4d7130ed 335 Gene3D G3DSA:3.30.540.10 1 169 5.5E-66 T 22-04-2016 TOLA_RS02510 f5a7c957871bb9f7f391714d4d7130ed 335 PANTHER PTHR30447:SF0 1 335 1.4E-172 T 22-04-2016 TOLA_RS02510 f5a7c957871bb9f7f391714d4d7130ed 335 PANTHER PTHR30447 1 335 1.4E-172 T 22-04-2016 TOLA_RS02510 f5a7c957871bb9f7f391714d4d7130ed 335 PIRSF PIRSF004532 1 332 2.8E-132 T 22-04-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TOLA_RS02510 f5a7c957871bb9f7f391714d4d7130ed 335 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 330 9.0E-165 T 22-04-2016 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TOLA_RS03305 e4ad10b9c4245c930217f1bb130bedc1 157 SMART SM00769 31 149 5.9E-19 T 22-04-2016 IPR013990 Water stress and hypersensitive response domain GO:0009269 TOLA_RS03305 e4ad10b9c4245c930217f1bb130bedc1 157 ProDom PD010978 LATE EMBRYOGENESIS ABUNDANT DESICCATION SIMILAR PROTECTANT PROTEINS RELATED EMBRYOGENESIS-ABUNDANT EMBRYOGENESIS-LIKE 29 99 6.0E-5 T 22-04-2016 TOLA_RS03305 e4ad10b9c4245c930217f1bb130bedc1 157 Pfam PF03168 Late embryogenesis abundant protein 52 143 1.8E-13 T 22-04-2016 IPR004864 Late embryogenesis abundant protein, LEA-14 TOLA_RS03305 e4ad10b9c4245c930217f1bb130bedc1 157 Gene3D G3DSA:2.60.40.10 45 148 2.5E-19 T 22-04-2016 IPR013783 Immunoglobulin-like fold TOLA_RS03305 e4ad10b9c4245c930217f1bb130bedc1 157 SUPERFAMILY SSF117070 7 151 1.7E-27 T 22-04-2016 TOLA_RS11260 ef2af8fb691d297a069d3365898a444a 181 SUPERFAMILY SSF53271 13 178 3.98E-51 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS11260 ef2af8fb691d297a069d3365898a444a 181 PANTHER PTHR11776:SF0 6 181 4.0E-77 T 22-04-2016 TOLA_RS11260 ef2af8fb691d297a069d3365898a444a 181 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 9 178 36.205 T 22-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 TOLA_RS11260 ef2af8fb691d297a069d3365898a444a 181 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 10 176 9.5E-67 T 22-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 TOLA_RS11260 ef2af8fb691d297a069d3365898a444a 181 Gene3D G3DSA:3.40.50.2020 6 178 6.3E-66 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS11260 ef2af8fb691d297a069d3365898a444a 181 PANTHER PTHR11776 6 181 4.0E-77 T 22-04-2016 TOLA_RS11260 ef2af8fb691d297a069d3365898a444a 181 Pfam PF00156 Phosphoribosyl transferase domain 29 150 1.0E-15 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 TOLA_RS13640 ca6b8f98ce939306cb172e5ee9352b78 433 Pfam PF13356 Domain of unknown function (DUF4102) 7 96 2.7E-12 T 22-04-2016 IPR025166 Domain of unknown function DUF4102 TOLA_RS13640 ca6b8f98ce939306cb172e5ee9352b78 433 Gene3D G3DSA:1.10.150.130 115 197 3.5E-10 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal TOLA_RS13640 ca6b8f98ce939306cb172e5ee9352b78 433 PANTHER PTHR30629:SF2 2 420 9.8E-63 T 22-04-2016 TOLA_RS13640 ca6b8f98ce939306cb172e5ee9352b78 433 Pfam PF00589 Phage integrase family 232 375 8.2E-11 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS13640 ca6b8f98ce939306cb172e5ee9352b78 433 Gene3D G3DSA:1.10.443.10 232 403 3.5E-17 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS13640 ca6b8f98ce939306cb172e5ee9352b78 433 PANTHER PTHR30629 2 420 9.8E-63 T 22-04-2016 TOLA_RS13640 ca6b8f98ce939306cb172e5ee9352b78 433 SUPERFAMILY SSF56349 115 410 1.38E-35 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TOLA_RS07120 f07103169465d51d2bee13e18e08e3a8 69 Pfam PF06786 Uncharacterised protein family (UPF0253) 5 67 8.4E-36 T 22-04-2016 IPR009624 Uncharacterised protein family UPF0253 TOLA_RS07120 f07103169465d51d2bee13e18e08e3a8 69 ProDom PD054643 UPF0253 YAEP CYTOPLASMIC VP2335 YPO1064.1/Y3113/YP2785 VC0872 VV2574 PBPRA2947 VV11836 7 65 9.0E-17 T 22-04-2016 IPR009624 Uncharacterised protein family UPF0253 TOLA_RS03925 f16633a0a3a5966c07f3d3051453110c 624 Pfam PF14718 Soluble lytic murein transglycosylase L domain 387 450 4.1E-20 T 22-04-2016 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 TOLA_RS03925 f16633a0a3a5966c07f3d3051453110c 624 Gene3D G3DSA:1.25.20.10 9 366 2.2E-93 T 22-04-2016 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 TOLA_RS03925 f16633a0a3a5966c07f3d3051453110c 624 SUPERFAMILY SSF53955 463 616 7.79E-47 T 22-04-2016 IPR023346 Lysozyme-like domain TOLA_RS03925 f16633a0a3a5966c07f3d3051453110c 624 PANTHER PTHR21666 444 615 2.4E-43 T 22-04-2016 TOLA_RS03925 f16633a0a3a5966c07f3d3051453110c 624 Pfam PF01464 Transglycosylase SLT domain 465 575 1.9E-28 T 22-04-2016 IPR008258 Transglycosylase SLT domain 1 TOLA_RS03925 f16633a0a3a5966c07f3d3051453110c 624 Gene3D G3DSA:1.10.1240.20 385 451 1.3E-19 T 22-04-2016 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 TOLA_RS03925 f16633a0a3a5966c07f3d3051453110c 624 Gene3D G3DSA:1.10.530.10 456 618 3.4E-50 T 22-04-2016 TOLA_RS03925 f16633a0a3a5966c07f3d3051453110c 624 SUPERFAMILY SSF48435 9 458 1.07E-107 T 22-04-2016 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 TOLA_RS11105 780caec9ff272a67883ad03f054992c9 209 PANTHER PTHR10344 1 205 9.2E-75 T 22-04-2016 TOLA_RS11105 780caec9ff272a67883ad03f054992c9 209 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 197 1.5E-62 T 22-04-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TOLA_RS11105 780caec9ff272a67883ad03f054992c9 209 Pfam PF02223 Thymidylate kinase 8 197 2.8E-56 T 22-04-2016 TOLA_RS11105 780caec9ff272a67883ad03f054992c9 209 SUPERFAMILY SSF52540 1 203 1.85E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11105 780caec9ff272a67883ad03f054992c9 209 Hamap MF_00165 Thymidylate kinase [tmk]. 4 205 28.524 T 22-04-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TOLA_RS11105 780caec9ff272a67883ad03f054992c9 209 ProSitePatterns PS01331 Thymidylate kinase signature. 94 106 - T 22-04-2016 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TOLA_RS11105 780caec9ff272a67883ad03f054992c9 209 Gene3D G3DSA:3.40.50.300 3 205 3.2E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11170 cf3dee775a5fb53a4c7f02a4aa5b3d91 314 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 16 312 1.9E-95 T 22-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS11170 cf3dee775a5fb53a4c7f02a4aa5b3d91 314 SUPERFAMILY SSF55174 19 70 2.65E-9 T 22-04-2016 TOLA_RS11170 cf3dee775a5fb53a4c7f02a4aa5b3d91 314 Pfam PF00849 RNA pseudouridylate synthase 101 247 6.0E-31 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS11170 cf3dee775a5fb53a4c7f02a4aa5b3d91 314 Pfam PF01479 S4 domain 20 66 1.6E-10 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS11170 cf3dee775a5fb53a4c7f02a4aa5b3d91 314 SUPERFAMILY SSF55120 93 312 1.04E-65 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS11170 cf3dee775a5fb53a4c7f02a4aa5b3d91 314 SMART SM00363 20 79 1.8E-9 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS11170 cf3dee775a5fb53a4c7f02a4aa5b3d91 314 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 139 153 - T 22-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS11170 cf3dee775a5fb53a4c7f02a4aa5b3d91 314 Gene3D G3DSA:3.10.290.10 20 68 6.0E-8 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS11170 cf3dee775a5fb53a4c7f02a4aa5b3d91 314 PANTHER PTHR11079 1 314 1.1E-154 T 22-04-2016 TOLA_RS11170 cf3dee775a5fb53a4c7f02a4aa5b3d91 314 PANTHER PTHR11079:SF84 1 314 1.1E-154 T 22-04-2016 TOLA_RS03020 4e403a07ebe6d997c49116ce33f374a7 176 Pfam PF01467 Cytidylyltransferase-like 8 146 5.1E-13 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TOLA_RS03020 4e403a07ebe6d997c49116ce33f374a7 176 SUPERFAMILY SSF52374 1 171 1.27E-29 T 22-04-2016 TOLA_RS03020 4e403a07ebe6d997c49116ce33f374a7 176 Gene3D G3DSA:3.40.50.620 1 173 2.2E-43 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS03020 4e403a07ebe6d997c49116ce33f374a7 176 PANTHER PTHR39321 1 165 2.7E-32 T 22-04-2016 TOLA_RS07800 7df54fc390513f4a2a842f466c7ae687 244 SUPERFAMILY SSF52833 67 230 1.22E-37 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS07800 7df54fc390513f4a2a842f466c7ae687 244 PANTHER PTHR13887 10 242 6.0E-55 T 22-04-2016 TOLA_RS07800 7df54fc390513f4a2a842f466c7ae687 244 Pfam PF13462 Thioredoxin 78 239 7.5E-23 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS07800 7df54fc390513f4a2a842f466c7ae687 244 PANTHER PTHR13887:SF25 10 242 6.0E-55 T 22-04-2016 TOLA_RS07800 7df54fc390513f4a2a842f466c7ae687 244 Gene3D G3DSA:3.40.30.10 70 242 7.2E-42 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS15100 704662f6ad26208d0288b186f5a2e10c 757 Gene3D G3DSA:3.20.20.210 4 389 9.6E-145 T 22-04-2016 TOLA_RS15100 704662f6ad26208d0288b186f5a2e10c 757 PANTHER PTHR30519 1 757 0.0 T 22-04-2016 TOLA_RS15100 704662f6ad26208d0288b186f5a2e10c 757 Gene3D G3DSA:3.20.20.210 392 756 8.2E-128 T 22-04-2016 TOLA_RS15100 704662f6ad26208d0288b186f5a2e10c 757 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 431 753 5.7E-155 T 22-04-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 TOLA_RS15100 704662f6ad26208d0288b186f5a2e10c 757 PIRSF PIRSF000382 2 757 0.0 T 22-04-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 TOLA_RS15100 704662f6ad26208d0288b186f5a2e10c 757 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 8 757 0.0 T 22-04-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 TOLA_RS15100 704662f6ad26208d0288b186f5a2e10c 757 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 3 757 35.736 T 22-04-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 TOLA_RS15100 704662f6ad26208d0288b186f5a2e10c 757 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 315 7.7E-121 T 22-04-2016 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 TOLA_RS15100 704662f6ad26208d0288b186f5a2e10c 757 SUPERFAMILY SSF51726 397 756 2.22E-113 T 22-04-2016 TOLA_RS15100 704662f6ad26208d0288b186f5a2e10c 757 SUPERFAMILY SSF51726 5 392 5.49E-108 T 22-04-2016 TOLA_RS15100 704662f6ad26208d0288b186f5a2e10c 757 PANTHER PTHR30519:SF0 1 757 0.0 T 22-04-2016 TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 Gene3D G3DSA:3.40.50.920 710 889 4.3E-73 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 PANTHER PTHR11624:SF67 556 771 0.0 T 22-04-2016 TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 PANTHER PTHR11624:SF67 475 538 0.0 T 22-04-2016 TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 PANTHER PTHR11624:SF67 366 455 0.0 T 22-04-2016 TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 PANTHER PTHR11624:SF67 78 297 0.0 T 22-04-2016 TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 PANTHER PTHR11624:SF67 790 872 0.0 T 22-04-2016 TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 SUPERFAMILY SSF52518 61 472 2.4E-139 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 Gene3D G3DSA:3.40.50.970 476 708 6.7E-120 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 PIRSF PIRSF000156 1 890 0.0 T 22-04-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 PANTHER PTHR11624 556 771 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 PANTHER PTHR11624 475 538 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 PANTHER PTHR11624 366 455 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 PANTHER PTHR11624 78 297 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 PANTHER PTHR11624 790 872 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 SUPERFAMILY SSF52518 477 704 8.01E-98 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 116 298 1.7E-8 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 365 428 1.3E-4 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 Gene3D G3DSA:3.40.50.970 61 472 2.6E-151 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 SUPERFAMILY SSF52922 705 889 7.06E-59 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS13100 a1a3143abf02f494e049d8f0f1d2f82b 890 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 6 889 0.0 T 22-04-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TOLA_RS11175 5125b2126118a4305bdb55c1dc5a7a4f 950 Pfam PF10150 Ribonuclease E/G family 121 390 3.9E-95 T 22-04-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 TOLA_RS11175 5125b2126118a4305bdb55c1dc5a7a4f 950 Gene3D G3DSA:2.40.50.140 32 124 2.6E-34 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS11175 5125b2126118a4305bdb55c1dc5a7a4f 950 Pfam PF00575 S1 RNA binding domain 36 118 4.7E-15 T 22-04-2016 IPR003029 S1 domain GO:0003676 TOLA_RS11175 5125b2126118a4305bdb55c1dc5a7a4f 950 PANTHER PTHR30001:SF1 1 834 0.0 T 22-04-2016 TOLA_RS11175 5125b2126118a4305bdb55c1dc5a7a4f 950 PANTHER PTHR30001 1 834 0.0 T 22-04-2016 TOLA_RS11175 5125b2126118a4305bdb55c1dc5a7a4f 950 SUPERFAMILY SSF50249 40 124 7.43E-19 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS11175 5125b2126118a4305bdb55c1dc5a7a4f 950 SMART SM00316 37 119 6.7E-10 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS11175 5125b2126118a4305bdb55c1dc5a7a4f 950 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 424 1.6E-170 T 22-04-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 TOLA_RS11175 5125b2126118a4305bdb55c1dc5a7a4f 950 Hamap MF_00970 Ribonuclease E [rne]. 1 892 34.365 T 22-04-2016 IPR028878 Ribonuclease E GO:0006396|GO:0008995 TOLA_RS12670 60f57ba8fd5a72437eea5c67753d5b4e 344 Gene3D G3DSA:3.40.50.300 112 270 5.9E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12670 60f57ba8fd5a72437eea5c67753d5b4e 344 Pfam PF03193 Protein of unknown function, DUF258 98 272 3.4E-58 T 22-04-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 TOLA_RS12670 60f57ba8fd5a72437eea5c67753d5b4e 344 PANTHER PTHR32120 4 344 1.6E-154 T 22-04-2016 TOLA_RS12670 60f57ba8fd5a72437eea5c67753d5b4e 344 PANTHER PTHR32120:SF2 4 344 1.6E-154 T 22-04-2016 TOLA_RS12670 60f57ba8fd5a72437eea5c67753d5b4e 344 SUPERFAMILY SSF52540 111 333 1.77E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12670 60f57ba8fd5a72437eea5c67753d5b4e 344 Gene3D G3DSA:1.10.40.50 272 338 3.9E-25 T 22-04-2016 TOLA_RS12670 60f57ba8fd5a72437eea5c67753d5b4e 344 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 72 330 1.3E-90 T 22-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 TOLA_RS12670 60f57ba8fd5a72437eea5c67753d5b4e 344 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 39 336 37.473 T 22-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 TOLA_RS11895 caae62d894622281e2a4ad20ddd3189d 391 Gene3D G3DSA:3.60.21.10 152 340 3.2E-24 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS11895 caae62d894622281e2a4ad20ddd3189d 391 Pfam PF00149 Calcineurin-like phosphoesterase 153 332 1.7E-11 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 TOLA_RS11895 caae62d894622281e2a4ad20ddd3189d 391 PANTHER PTHR31302 8 387 1.2E-44 T 22-04-2016 TOLA_RS11895 caae62d894622281e2a4ad20ddd3189d 391 SUPERFAMILY SSF56300 151 388 6.61E-29 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS10930 5ebcd977d209ee2569c0ef3dad5de844 451 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 448 7.3E-126 T 22-04-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS10930 5ebcd977d209ee2569c0ef3dad5de844 451 PANTHER PTHR21499 5 449 2.2E-145 T 22-04-2016 TOLA_RS10930 5ebcd977d209ee2569c0ef3dad5de844 451 Pfam PF00696 Amino acid kinase family 3 278 1.4E-51 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS10930 5ebcd977d209ee2569c0ef3dad5de844 451 PIRSF PIRSF000726 2 451 6.0E-133 T 22-04-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS10930 5ebcd977d209ee2569c0ef3dad5de844 451 SUPERFAMILY SSF53633 4 292 7.46E-79 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS10930 5ebcd977d209ee2569c0ef3dad5de844 451 PANTHER PTHR21499:SF3 5 449 2.2E-145 T 22-04-2016 TOLA_RS10930 5ebcd977d209ee2569c0ef3dad5de844 451 SUPERFAMILY SSF55021 297 358 1.37E-15 T 22-04-2016 TOLA_RS10930 5ebcd977d209ee2569c0ef3dad5de844 451 Gene3D G3DSA:3.40.1160.10 3 50 5.2E-64 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS10930 5ebcd977d209ee2569c0ef3dad5de844 451 Gene3D G3DSA:3.40.1160.10 104 294 5.2E-64 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS10930 5ebcd977d209ee2569c0ef3dad5de844 451 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 3 448 4.5E-131 T 22-04-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS10930 5ebcd977d209ee2569c0ef3dad5de844 451 SUPERFAMILY SSF55021 377 448 4.01E-15 T 22-04-2016 TOLA_RS10930 5ebcd977d209ee2569c0ef3dad5de844 451 ProSitePatterns PS00324 Aspartokinase signature. 6 14 - T 22-04-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 2.5E-19 T 22-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 2.5E-19 T 22-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 2.5E-19 T 22-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 2.5E-19 T 22-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 PANTHER PTHR11451 4 244 2.7E-158 T 22-04-2016 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 PANTHER PTHR11451 401 574 2.7E-158 T 22-04-2016 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 Pfam PF03129 Anticodon binding domain 477 570 2.0E-24 T 22-04-2016 IPR004154 Anticodon-binding TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 PIRSF PIRSF001535 1 574 5.2E-275 T 22-04-2016 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 570 5.1E-253 T 22-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 SUPERFAMILY SSF52954 466 573 3.17E-33 T 22-04-2016 IPR004154 Anticodon-binding TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 461 2.1E-48 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 Gene3D G3DSA:3.40.50.800 474 573 3.7E-36 T 22-04-2016 IPR004154 Anticodon-binding TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 SUPERFAMILY SSF55826 218 392 7.19E-33 T 22-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 Gene3D G3DSA:3.30.930.10 10 234 2.8E-105 T 22-04-2016 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 Gene3D G3DSA:3.30.930.10 391 473 2.8E-105 T 22-04-2016 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 Pfam PF04073 Aminoacyl-tRNA editing domain 257 378 2.5E-28 T 22-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 573 42.301 T 22-04-2016 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 PANTHER PTHR11451:SF3 4 244 2.7E-158 T 22-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 PANTHER PTHR11451:SF3 401 574 2.7E-158 T 22-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 Gene3D G3DSA:3.90.960.10 254 390 1.7E-33 T 22-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 SUPERFAMILY SSF55681 409 480 8.62E-105 T 22-04-2016 TOLA_RS04235 91c94a3b2436baa07bcf7a275f8074ff 574 SUPERFAMILY SSF55681 10 237 8.62E-105 T 22-04-2016 TOLA_RS15835 03d1f7f094edb4d598cd554a993a43dc 489 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 252 439 5.7E-33 T 22-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TOLA_RS15835 03d1f7f094edb4d598cd554a993a43dc 489 TIGRFAM TIGR01312 XylB: xylulokinase 3 479 7.4E-179 T 22-04-2016 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 TOLA_RS15835 03d1f7f094edb4d598cd554a993a43dc 489 PANTHER PTHR10196:SF72 1 480 7.8E-199 T 22-04-2016 TOLA_RS15835 03d1f7f094edb4d598cd554a993a43dc 489 Gene3D G3DSA:3.30.420.40 245 481 2.2E-49 T 22-04-2016 TOLA_RS15835 03d1f7f094edb4d598cd554a993a43dc 489 SUPERFAMILY SSF53067 245 481 1.89E-57 T 22-04-2016 TOLA_RS15835 03d1f7f094edb4d598cd554a993a43dc 489 SUPERFAMILY SSF53067 2 246 2.25E-78 T 22-04-2016 TOLA_RS15835 03d1f7f094edb4d598cd554a993a43dc 489 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 128 140 - T 22-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 TOLA_RS15835 03d1f7f094edb4d598cd554a993a43dc 489 Gene3D G3DSA:3.30.420.40 1 243 1.7E-72 T 22-04-2016 TOLA_RS15835 03d1f7f094edb4d598cd554a993a43dc 489 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 243 1.4E-78 T 22-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TOLA_RS15835 03d1f7f094edb4d598cd554a993a43dc 489 PANTHER PTHR10196 1 480 7.8E-199 T 22-04-2016 TOLA_RS15835 03d1f7f094edb4d598cd554a993a43dc 489 PIRSF PIRSF000538 1 486 3.2E-135 T 22-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 Gene3D G3DSA:2.160.20.10 250 436 1.1E-14 T 22-04-2016 IPR012334 Pectin lyase fold TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 SUPERFAMILY SSF51126 77 147 2.44E-23 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 SUPERFAMILY SSF51126 200 417 2.44E-23 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 SMART SM00710 227 249 890.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 SMART SM00710 251 273 230.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 SMART SM00710 205 226 4100.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 SMART SM00710 299 321 77.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 SMART SM00710 322 343 61.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 SMART SM00710 345 367 7.8 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 SMART SM00710 275 297 3.8 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 Pfam PF05048 Periplasmic copper-binding protein (NosD) 210 365 4.9E-15 T 22-04-2016 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 292 336 3.5E-11 T 22-04-2016 IPR022441 Parallel beta-helix repeat-2 TOLA_RS07240 13b9ba450ce9e35caa183d4301746c9c 444 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 275 313 2.6E-5 T 22-04-2016 IPR022441 Parallel beta-helix repeat-2 TOLA_RS09870 370477db9acd1c37b836d1c4bfdd2139 285 Pfam PF01418 Helix-turn-helix domain, rpiR family 10 79 1.5E-18 T 22-04-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 TOLA_RS09870 370477db9acd1c37b836d1c4bfdd2139 285 Pfam PF01380 SIS domain 130 259 8.3E-25 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 TOLA_RS09870 370477db9acd1c37b836d1c4bfdd2139 285 SUPERFAMILY SSF46689 9 81 6.09E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09870 370477db9acd1c37b836d1c4bfdd2139 285 Gene3D G3DSA:1.10.10.10 8 77 2.1E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09870 370477db9acd1c37b836d1c4bfdd2139 285 Gene3D G3DSA:3.40.50.10490 104 276 4.2E-39 T 22-04-2016 TOLA_RS09870 370477db9acd1c37b836d1c4bfdd2139 285 PANTHER PTHR30514 1 274 3.5E-73 T 22-04-2016 TOLA_RS09870 370477db9acd1c37b836d1c4bfdd2139 285 PANTHER PTHR30514:SF1 1 274 3.5E-73 T 22-04-2016 TOLA_RS09870 370477db9acd1c37b836d1c4bfdd2139 285 SUPERFAMILY SSF53697 97 281 2.78E-43 T 22-04-2016 TOLA_RS08280 44615ce6319774bc5072a066b19eedcf 533 SUPERFAMILY SSF48371 121 231 4.8E-6 T 22-04-2016 IPR016024 Armadillo-type fold GO:0005488 TOLA_RS08280 44615ce6319774bc5072a066b19eedcf 533 PANTHER PTHR11795 1 532 1.2E-139 T 22-04-2016 TOLA_RS08280 44615ce6319774bc5072a066b19eedcf 533 PANTHER PTHR11795:SF349 1 532 1.2E-139 T 22-04-2016 TOLA_RS08280 44615ce6319774bc5072a066b19eedcf 533 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 242 529 3.2E-126 T 22-04-2016 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type TOLA_RS08280 44615ce6319774bc5072a066b19eedcf 533 Pfam PF02653 Branched-chain amino acid transport system / permease component 246 515 2.7E-54 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS08280 44615ce6319774bc5072a066b19eedcf 533 Gene3D G3DSA:1.25.10.10 128 235 4.8E-9 T 22-04-2016 IPR011989 Armadillo-like helical TOLA_RS13680 687a56e662813cfd477c59b4636d3a7c 484 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 42 445 1.9E-110 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TOLA_RS13680 687a56e662813cfd477c59b4636d3a7c 484 SUPERFAMILY SSF56601 45 454 4.75E-80 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS13680 687a56e662813cfd477c59b4636d3a7c 484 PANTHER PTHR30023 27 469 6.6E-99 T 22-04-2016 TOLA_RS13680 687a56e662813cfd477c59b4636d3a7c 484 PANTHER PTHR30023:SF0 27 469 6.6E-99 T 22-04-2016 TOLA_RS13680 687a56e662813cfd477c59b4636d3a7c 484 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 43 443 1.0E-112 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TOLA_RS13680 687a56e662813cfd477c59b4636d3a7c 484 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 420 433 3.5E-34 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TOLA_RS13680 687a56e662813cfd477c59b4636d3a7c 484 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 54 73 3.5E-34 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TOLA_RS13680 687a56e662813cfd477c59b4636d3a7c 484 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 341 355 3.5E-34 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TOLA_RS13680 687a56e662813cfd477c59b4636d3a7c 484 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 356 370 3.5E-34 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TOLA_RS13680 687a56e662813cfd477c59b4636d3a7c 484 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 282 304 3.5E-34 T 22-04-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 TOLA_RS13680 687a56e662813cfd477c59b4636d3a7c 484 Gene3D G3DSA:3.40.710.10 223 455 8.4E-54 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS09500 c0bedb1ae5d28e8b435fcc62632f0f62 254 SUPERFAMILY SSF46785 6 65 4.1E-10 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09500 c0bedb1ae5d28e8b435fcc62632f0f62 254 SMART SM01134 74 235 2.2E-67 T 22-04-2016 TOLA_RS09500 c0bedb1ae5d28e8b435fcc62632f0f62 254 Pfam PF00455 DeoR C terminal sensor domain 76 234 8.1E-49 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain TOLA_RS09500 c0bedb1ae5d28e8b435fcc62632f0f62 254 SMART SM00420 6 58 3.8E-11 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS09500 c0bedb1ae5d28e8b435fcc62632f0f62 254 PANTHER PTHR30363 1 253 7.5E-97 T 22-04-2016 TOLA_RS09500 c0bedb1ae5d28e8b435fcc62632f0f62 254 Gene3D G3DSA:3.40.50.1360 77 225 8.7E-16 T 22-04-2016 TOLA_RS09500 c0bedb1ae5d28e8b435fcc62632f0f62 254 Gene3D G3DSA:1.10.10.10 6 64 7.0E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09500 c0bedb1ae5d28e8b435fcc62632f0f62 254 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 4.5E-14 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS09500 c0bedb1ae5d28e8b435fcc62632f0f62 254 SUPERFAMILY SSF100950 76 235 3.29E-33 T 22-04-2016 TOLA_RS09500 c0bedb1ae5d28e8b435fcc62632f0f62 254 PANTHER PTHR30363:SF15 1 253 7.5E-97 T 22-04-2016 TOLA_RS06935 ea4c6d67ad2cb31f91b88cc3d5fb0bee 325 TIGRFAM TIGR03637 cas1_YPEST: CRISPR-associated endonuclease Cas1, subtype I-F/YPEST 12 317 1.6E-154 T 22-04-2016 IPR019857 CRISPR-associated protein Cas1, YPEST subtype TOLA_RS06935 ea4c6d67ad2cb31f91b88cc3d5fb0bee 325 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 19 324 9.131 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 TOLA_RS06935 ea4c6d67ad2cb31f91b88cc3d5fb0bee 325 Pfam PF01867 CRISPR associated protein Cas1 26 313 3.6E-28 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 TOLA_RS06935 ea4c6d67ad2cb31f91b88cc3d5fb0bee 325 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 19 295 1.0E-70 T 22-04-2016 IPR002729 CRISPR-associated protein Cas1 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 SUPERFAMILY SSF52540 159 545 4.12E-100 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 844 2.2E-24 T 22-04-2016 IPR019489 Clp ATPase, C-terminal TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 855 0.0 T 22-04-2016 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 22-04-2016 IPR028299 ClpA/B, conserved site 2 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 5.6E-42 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 5.6E-42 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 5.6E-42 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 5.6E-42 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 Gene3D G3DSA:1.10.8.60 343 427 1.3E-37 T 22-04-2016 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 SMART SM01086 766 855 4.4E-35 T 22-04-2016 IPR019489 Clp ATPase, C-terminal TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 PANTHER PTHR11638 1 856 0.0 T 22-04-2016 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 PANTHER PTHR11638:SF18 1 856 0.0 T 22-04-2016 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 Gene3D G3DSA:1.10.8.60 777 856 5.4E-29 T 22-04-2016 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 Gene3D G3DSA:1.10.1780.10 1 148 1.3E-43 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 Gene3D G3DSA:3.40.50.300 552 776 8.6E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 759 3.8E-56 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 SMART SM00382 597 736 1.6E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 SMART SM00382 198 342 4.2E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 Gene3D G3DSA:3.40.50.300 160 342 5.0E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 316 1.5E-13 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 SUPERFAMILY SSF81923 4 156 4.41E-40 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 8.0E-11 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 6.0E-11 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 22-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 TOLA_RS14180 24d351d5c191a231ce9ddb421411f126 858 SUPERFAMILY SSF52540 546 854 8.73E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09850 83b47ef88cd14f3e01c6b036a3281661 342 PANTHER PTHR37419 19 342 5.0E-96 T 22-04-2016 TOLA_RS09850 83b47ef88cd14f3e01c6b036a3281661 342 Pfam PF07805 HipA-like N-terminal domain 57 141 6.3E-22 T 22-04-2016 IPR012894 HipA, N-terminal subdomain 2 TOLA_RS09850 83b47ef88cd14f3e01c6b036a3281661 342 PANTHER PTHR37419:SF1 19 342 5.0E-96 T 22-04-2016 TOLA_RS09850 83b47ef88cd14f3e01c6b036a3281661 342 Pfam PF07804 HipA-like C-terminal domain 148 304 8.2E-16 T 22-04-2016 IPR012893 HipA-like, C-terminal TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 PANTHER PTHR23133:SF2 12 99 5.4E-158 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 PANTHER PTHR23133:SF2 165 357 5.4E-158 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 228 241 - T 22-04-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 Gene3D G3DSA:3.30.230.40 260 357 5.3E-30 T 22-04-2016 TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 Hamap MF_01022 Histidine biosynthesis bifunctional protein HisB [hisB]. 4 357 53.343 T 22-04-2016 IPR020566 Histidine biosynthesis bifunctional protein HisB GO:0000105|GO:0004401|GO:0004424 KEGG: 00340+4.2.1.19+3.1.3.15|UniPathway: UPA00031|UniPathway: UPA00031 TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 SUPERFAMILY SSF54211 254 344 7.33E-30 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 TIGRFAM TIGR01261 hisB_Nterm: histidinol-phosphatase 5 164 7.7E-72 T 22-04-2016 IPR005954 Histidinol-phosphatase GO:0000105|GO:0004401|GO:0004424|GO:0005737 KEGG: 00340+4.2.1.19+3.1.3.15|UniPathway: UPA00031|UniPathway: UPA00031 TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 169 357 37.84 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 Pfam PF08645 Polynucleotide kinase 3 phosphatase 7 132 2.0E-5 T 22-04-2016 IPR013954 Polynucleotide kinase 3 phosphatase TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 7 147 1.1E-42 T 22-04-2016 IPR006543 Histidinol-phosphate phosphatase GO:0016791 TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 6 151 1.1E-26 T 22-04-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 PANTHER PTHR23133 12 99 5.4E-158 T 22-04-2016 TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 PANTHER PTHR23133 165 357 5.4E-158 T 22-04-2016 TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 Gene3D G3DSA:3.30.230.40 169 255 1.4E-38 T 22-04-2016 TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 SUPERFAMILY SSF54211 169 253 5.31E-33 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 SUPERFAMILY SSF56784 3 159 2.2E-39 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 198 339 1.3E-65 T 22-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 TOLA_RS08835 8dab6827670af0577cd65b4492eae4b8 357 Gene3D G3DSA:3.40.50.1000 3 162 2.2E-41 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS02150 faa06b09feeec827bcc05db644e8a88e 446 PANTHER PTHR11662 11 446 3.1E-178 T 22-04-2016 TOLA_RS02150 faa06b09feeec827bcc05db644e8a88e 446 Gene3D G3DSA:1.20.1250.20 245 438 4.5E-30 T 22-04-2016 TOLA_RS02150 faa06b09feeec827bcc05db644e8a88e 446 PANTHER PTHR11662:SF18 11 446 3.1E-178 T 22-04-2016 TOLA_RS02150 faa06b09feeec827bcc05db644e8a88e 446 SUPERFAMILY SSF103473 11 443 3.92E-78 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS02150 faa06b09feeec827bcc05db644e8a88e 446 Gene3D G3DSA:1.20.1250.20 13 214 1.9E-46 T 22-04-2016 TOLA_RS02150 faa06b09feeec827bcc05db644e8a88e 446 PIRSF PIRSF002808 2 446 5.4E-35 T 22-04-2016 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 TOLA_RS02150 faa06b09feeec827bcc05db644e8a88e 446 Pfam PF00083 Sugar (and other) transporter 331 436 4.4E-5 T 22-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TOLA_RS02150 faa06b09feeec827bcc05db644e8a88e 446 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 29 436 3.4E-121 T 22-04-2016 IPR004744 D-galactonate transporter GO:0005215|GO:0006810|GO:0016021 TOLA_RS02150 faa06b09feeec827bcc05db644e8a88e 446 Pfam PF07690 Major Facilitator Superfamily 26 318 3.0E-51 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 Pfam PF00158 Sigma-54 interaction domain 211 378 4.0E-73 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 Gene3D G3DSA:3.30.450.40 19 179 6.0E-24 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 423 432 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 Gene3D G3DSA:1.10.8.60 384 456 3.2E-22 T 22-04-2016 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 Pfam PF13185 GAF domain 36 177 7.7E-10 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 Pfam PF02954 Bacterial regulatory protein, Fis family 487 521 9.8E-13 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 SUPERFAMILY SSF52540 211 451 3.77E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 SMART SM00382 231 374 1.7E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 Gene3D G3DSA:3.40.50.300 208 383 1.5E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 SMART SM00065 37 188 1.0E-23 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 SUPERFAMILY SSF46689 423 525 1.08E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 Gene3D G3DSA:1.10.10.60 487 521 1.2E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 235 248 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 297 312 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 489 506 2.0E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 506 526 2.0E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 SUPERFAMILY SSF55781 19 179 1.44E-21 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 TIGRFAM TIGR01817 nifA: Nif-specific regulatory protein 20 530 1.3E-213 T 22-04-2016 IPR010113 Nif-specific regulatory protein GO:0003700|GO:0006355|GO:0009399 TOLA_RS11835 53158a9fa872d6aa25e50bec9725f8e5 530 PANTHER PTHR32071 163 530 1.8E-156 T 22-04-2016 TOLA_RS07425 5213d158baef48dae03d53dcc9066e2d 543 SUPERFAMILY SSF52540 251 320 5.06E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07425 5213d158baef48dae03d53dcc9066e2d 543 SUPERFAMILY SSF52540 1 178 5.06E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07425 5213d158baef48dae03d53dcc9066e2d 543 PANTHER PTHR32182:SF12 1 543 1.0E-95 T 22-04-2016 TOLA_RS07425 5213d158baef48dae03d53dcc9066e2d 543 Pfam PF11398 Protein of unknown function (DUF2813) 1 364 1.0E-103 T 22-04-2016 IPR022602 Protein of unknown function DUF2813 TOLA_RS07425 5213d158baef48dae03d53dcc9066e2d 543 PANTHER PTHR32182 1 543 1.0E-95 T 22-04-2016 TOLA_RS07425 5213d158baef48dae03d53dcc9066e2d 543 Gene3D G3DSA:3.40.50.300 1 333 5.1E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 PANTHER PTHR32039 1 502 1.8E-256 T 22-04-2016 TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 Gene3D G3DSA:3.40.50.300 192 385 2.0E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 SUPERFAMILY SSF52540 187 500 6.35E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 400 492 8.5E-29 T 22-04-2016 IPR025158 Mg chelatase-related protein, C-terminal domain TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 289 303 4.4E-5 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 317 330 4.4E-5 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 209 224 4.4E-5 T 22-04-2016 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006260 TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 1.7E-46 T 22-04-2016 TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 PANTHER PTHR32039:SF7 1 502 1.8E-256 T 22-04-2016 IPR004482 Mg chelatase-related protein TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 390 4.5E-89 T 22-04-2016 IPR000523 Magnesium chelatase ChlI domain TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 SMART SM00382 210 389 5.3E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 Gene3D G3DSA:3.30.230.10 5 191 9.5E-31 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 SUPERFAMILY SSF54211 8 169 1.18E-32 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS15705 62cd47e4f6002fdd9d8affef6aa57e95 506 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 492 3.5E-209 T 22-04-2016 IPR004482 Mg chelatase-related protein TOLA_RS16390 31dd85bfbd0b35fe8e77b7c885ee3999 525 Gene3D G3DSA:2.70.70.10 365 494 1.6E-40 T 22-04-2016 TOLA_RS16390 31dd85bfbd0b35fe8e77b7c885ee3999 525 PANTHER PTHR21666:SF207 277 524 2.4E-82 T 22-04-2016 TOLA_RS16390 31dd85bfbd0b35fe8e77b7c885ee3999 525 SUPERFAMILY SSF51261 263 494 1.36E-59 T 22-04-2016 IPR011055 Duplicated hybrid motif TOLA_RS16390 31dd85bfbd0b35fe8e77b7c885ee3999 525 Pfam PF01551 Peptidase family M23 399 491 5.6E-29 T 22-04-2016 IPR016047 Peptidase M23 TOLA_RS16390 31dd85bfbd0b35fe8e77b7c885ee3999 525 Pfam PF04225 Opacity-associated protein A LysM-like domain 104 178 2.2E-6 T 22-04-2016 IPR007340 Opacity-associated protein A TOLA_RS16390 31dd85bfbd0b35fe8e77b7c885ee3999 525 PANTHER PTHR21666 277 524 2.4E-82 T 22-04-2016 TOLA_RS04815 b350c5f2eb6bd637463e3fcf0bce97cc 182 Pfam PF04279 Intracellular septation protein A 1 175 6.6E-66 T 22-04-2016 IPR006008 Intracellular septation protein A GO:0016021 TOLA_RS04815 b350c5f2eb6bd637463e3fcf0bce97cc 182 PANTHER PTHR36917 1 182 5.1E-70 T 22-04-2016 TOLA_RS04815 b350c5f2eb6bd637463e3fcf0bce97cc 182 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 176 18.378 T 22-04-2016 IPR006008 Intracellular septation protein A GO:0016021 TOLA_RS04815 b350c5f2eb6bd637463e3fcf0bce97cc 182 PANTHER PTHR36917:SF1 1 182 5.1E-70 T 22-04-2016 TOLA_RS04815 b350c5f2eb6bd637463e3fcf0bce97cc 182 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 176 1.8E-62 T 22-04-2016 IPR006008 Intracellular septation protein A GO:0016021 TOLA_RS10820 2679cbe21210b87b8c8205dcfc448fb1 385 SUPERFAMILY SSF53218 1 202 2.36E-34 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS10820 2679cbe21210b87b8c8205dcfc448fb1 385 Pfam PF00994 Probable molybdopterin binding domain 4 169 6.4E-30 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS10820 2679cbe21210b87b8c8205dcfc448fb1 385 Gene3D G3DSA:3.40.980.10 3 198 2.6E-28 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS10820 2679cbe21210b87b8c8205dcfc448fb1 385 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 2 261 4.6E-74 T 22-04-2016 IPR008135 Competence-induced protein CinA TOLA_RS10820 2679cbe21210b87b8c8205dcfc448fb1 385 SMART SM00852 4 171 6.3E-34 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS10820 2679cbe21210b87b8c8205dcfc448fb1 385 PANTHER PTHR13939:SF3 1 279 1.4E-101 T 22-04-2016 TOLA_RS10820 2679cbe21210b87b8c8205dcfc448fb1 385 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 164 9.9E-27 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS10820 2679cbe21210b87b8c8205dcfc448fb1 385 PANTHER PTHR13939 1 279 1.4E-101 T 22-04-2016 TOLA_RS12485 5b6ae4fe7efdc5494b59a1d6231ca93d 105 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 8 68 8.0E-9 T 22-04-2016 TOLA_RS12485 5b6ae4fe7efdc5494b59a1d6231ca93d 105 SMART SM00966 8 53 1.7E-9 T 22-04-2016 IPR007159 SpoVT-AbrB domain GO:0003677 TOLA_RS12485 5b6ae4fe7efdc5494b59a1d6231ca93d 105 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 8 71 1.5E-16 T 22-04-2016 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 TOLA_RS12485 5b6ae4fe7efdc5494b59a1d6231ca93d 105 SUPERFAMILY SSF89447 2 49 7.85E-11 T 22-04-2016 TOLA_RS12485 5b6ae4fe7efdc5494b59a1d6231ca93d 105 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 9 48 5.0E-10 T 22-04-2016 IPR007159 SpoVT-AbrB domain GO:0003677 TOLA_RS12485 5b6ae4fe7efdc5494b59a1d6231ca93d 105 Gene3D G3DSA:2.10.260.10 6 47 2.5E-8 T 22-04-2016 TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 PRINTS PR00147 DNA photolyase signature 340 358 2.8E-29 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 PRINTS PR00147 DNA photolyase signature 379 393 2.8E-29 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 PRINTS PR00147 DNA photolyase signature 320 336 2.8E-29 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 PRINTS PR00147 DNA photolyase signature 143 159 2.8E-29 T 22-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 Gene3D G3DSA:1.25.40.80 196 278 2.2E-40 T 22-04-2016 TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 Gene3D G3DSA:1.25.40.80 148 164 2.2E-40 T 22-04-2016 TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 SUPERFAMILY SSF52425 2 180 2.09E-48 T 22-04-2016 IPR006050 DNA photolyase, N-terminal TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 Gene3D G3DSA:3.40.50.620 2 147 3.2E-42 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 SUPERFAMILY SSF48173 185 463 1.14E-106 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 PANTHER PTHR11455:SF18 1 465 1.1E-190 T 22-04-2016 TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 Pfam PF00875 DNA photolyase 3 163 3.9E-44 T 22-04-2016 IPR006050 DNA photolyase, N-terminal TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 320 332 - T 22-04-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 Gene3D G3DSA:1.10.579.10 279 464 2.5E-77 T 22-04-2016 TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 Pfam PF03441 FAD binding domain of DNA photolyase 270 464 2.7E-85 T 22-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 340 359 - T 22-04-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal TOLA_RS05705 593f714498ff19fd06a6418b4841fd97 465 PANTHER PTHR11455 1 465 1.1E-190 T 22-04-2016 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 SUPERFAMILY SSF54713 150 287 9.0E-51 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 Pfam PF00889 Elongation factor TS 71 270 4.4E-65 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 SUPERFAMILY SSF46934 3 56 1.15E-18 T 22-04-2016 IPR009060 UBA-like GO:0005515 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 PANTHER PTHR11741 1 290 2.6E-138 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 Gene3D G3DSA:1.10.8.10 3 55 2.1E-27 T 22-04-2016 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 Hamap MF_00050 Elongation factor Ts [tsf]. 1 287 78.815 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 Gene3D G3DSA:3.30.479.20 57 145 1.2E-15 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 22-04-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 Gene3D G3DSA:3.30.479.20 150 185 6.9E-25 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 Gene3D G3DSA:3.30.479.20 234 269 6.9E-25 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 Gene3D G3DSA:1.10.286.20 190 233 1.9E-20 T 22-04-2016 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 287 1.3E-113 T 22-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 TOLA_RS10730 3224d801c7d2355373135f975615ac0d 292 SUPERFAMILY SSF54713 56 146 6.54E-20 T 22-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 TOLA_RS11705 fdde258dde3ca42e1b7f3d1d9be00b45 810 PANTHER PTHR30191 6 810 0.0 T 22-04-2016 TOLA_RS11705 fdde258dde3ca42e1b7f3d1d9be00b45 810 ProSitePatterns PS00850 Glycine radical domain signature. 780 788 - T 22-04-2016 IPR019777 Formate C-acetyltransferase glycine radical, conserved site TOLA_RS11705 fdde258dde3ca42e1b7f3d1d9be00b45 810 TIGRFAM TIGR01774 PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family 8 809 0.0 T 22-04-2016 IPR010098 Glycyl radical enzyme, PFL2/glycerol dehydratase family KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493|UniPathway: UPA00920 TOLA_RS11705 fdde258dde3ca42e1b7f3d1d9be00b45 810 PIRSF PIRSF000379 53 810 6.9E-178 T 22-04-2016 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493|UniPathway: UPA00920 TOLA_RS11705 fdde258dde3ca42e1b7f3d1d9be00b45 810 PANTHER PTHR30191:SF6 6 810 0.0 T 22-04-2016 TOLA_RS11705 fdde258dde3ca42e1b7f3d1d9be00b45 810 SUPERFAMILY SSF51998 4 808 6.71E-224 T 22-04-2016 TOLA_RS11705 fdde258dde3ca42e1b7f3d1d9be00b45 810 Pfam PF01228 Glycine radical 687 790 1.7E-30 T 22-04-2016 IPR001150 Glycine radical domain GO:0003824|GO:0008152 TOLA_RS11705 fdde258dde3ca42e1b7f3d1d9be00b45 810 Pfam PF02901 Pyruvate formate lyase-like 10 670 4.6E-205 T 22-04-2016 IPR004184 Pyruvate formate lyase domain GO:0003824 TOLA_RS11705 fdde258dde3ca42e1b7f3d1d9be00b45 810 Gene3D G3DSA:3.20.70.20 8 808 4.7E-259 T 22-04-2016 TOLA_RS09660 a9eb43bced3057bed3903359b5cb0aaa 287 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 70 278 1.2E-58 T 22-04-2016 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 TOLA_RS09660 a9eb43bced3057bed3903359b5cb0aaa 287 ProSitePatterns PS01087 Radical activating enzymes signature. 30 51 - T 22-04-2016 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 TOLA_RS09660 a9eb43bced3057bed3903359b5cb0aaa 287 Gene3D G3DSA:3.30.70.20 42 88 8.8E-5 T 22-04-2016 TOLA_RS09660 a9eb43bced3057bed3903359b5cb0aaa 287 PANTHER PTHR30352:SF10 89 287 1.8E-101 T 22-04-2016 TOLA_RS09660 a9eb43bced3057bed3903359b5cb0aaa 287 PANTHER PTHR30352:SF10 18 71 1.8E-101 T 22-04-2016 TOLA_RS09660 a9eb43bced3057bed3903359b5cb0aaa 287 Gene3D G3DSA:3.80.30.10 111 286 7.3E-55 T 22-04-2016 TOLA_RS09660 a9eb43bced3057bed3903359b5cb0aaa 287 SUPERFAMILY SSF54862 9 86 3.18E-5 T 22-04-2016 TOLA_RS09660 a9eb43bced3057bed3903359b5cb0aaa 287 Pfam PF04055 Radical SAM superfamily 36 225 1.2E-24 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS09660 a9eb43bced3057bed3903359b5cb0aaa 287 Pfam PF13353 4Fe-4S single cluster domain 29 152 7.8E-14 T 22-04-2016 TOLA_RS09660 a9eb43bced3057bed3903359b5cb0aaa 287 PANTHER PTHR30352 89 287 1.8E-101 T 22-04-2016 TOLA_RS09660 a9eb43bced3057bed3903359b5cb0aaa 287 PANTHER PTHR30352 18 71 1.8E-101 T 22-04-2016 TOLA_RS09660 a9eb43bced3057bed3903359b5cb0aaa 287 SUPERFAMILY SSF102114 37 254 3.53E-18 T 22-04-2016 TOLA_RS13450 1c926365af4037a337cc5d412cce27a8 166 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 23 165 6.5E-51 T 22-04-2016 TOLA_RS13450 1c926365af4037a337cc5d412cce27a8 166 PANTHER PTHR10371 12 165 1.5E-106 T 22-04-2016 TOLA_RS13450 1c926365af4037a337cc5d412cce27a8 166 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 123 141 - T 22-04-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 TOLA_RS13450 1c926365af4037a337cc5d412cce27a8 166 SUPERFAMILY SSF52833 16 165 1.12E-49 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS13450 1c926365af4037a337cc5d412cce27a8 166 Gene3D G3DSA:3.40.30.10 86 164 2.6E-8 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS13450 1c926365af4037a337cc5d412cce27a8 166 PIRSF PIRSF000216 2 166 4.1E-52 T 22-04-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 TOLA_RS13450 1c926365af4037a337cc5d412cce27a8 166 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 22 165 6.4E-53 T 22-04-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 TOLA_RS13450 1c926365af4037a337cc5d412cce27a8 166 PANTHER PTHR10371:SF7 12 165 1.5E-106 T 22-04-2016 TOLA_RS07510 ddcac1f13252c50ad916b865605b65d1 398 PANTHER PTHR23505 11 397 3.3E-143 T 22-04-2016 TOLA_RS07510 ddcac1f13252c50ad916b865605b65d1 398 Pfam PF07690 Major Facilitator Superfamily 238 389 2.1E-15 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS07510 ddcac1f13252c50ad916b865605b65d1 398 Pfam PF07690 Major Facilitator Superfamily 24 209 3.6E-25 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS07510 ddcac1f13252c50ad916b865605b65d1 398 SUPERFAMILY SSF103473 7 391 2.22E-56 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS07510 ddcac1f13252c50ad916b865605b65d1 398 PANTHER PTHR23505:SF8 11 397 3.3E-143 T 22-04-2016 TOLA_RS07510 ddcac1f13252c50ad916b865605b65d1 398 Gene3D G3DSA:1.20.1250.20 16 198 1.4E-21 T 22-04-2016 TOLA_RS07510 ddcac1f13252c50ad916b865605b65d1 398 Gene3D G3DSA:1.20.1250.20 224 389 2.6E-20 T 22-04-2016 TOLA_RS03150 bca4000ce9f6ee2434266d3905be2d59 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 330 5.1E-45 T 22-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TOLA_RS03150 bca4000ce9f6ee2434266d3905be2d59 572 SUPERFAMILY SSF52518 2 180 5.5E-66 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS03150 bca4000ce9f6ee2434266d3905be2d59 572 Gene3D G3DSA:3.40.50.1220 190 357 3.2E-66 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain TOLA_RS03150 bca4000ce9f6ee2434266d3905be2d59 572 SUPERFAMILY SSF52518 372 565 1.0E-71 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS03150 bca4000ce9f6ee2434266d3905be2d59 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 394 542 7.4E-51 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TOLA_RS03150 bca4000ce9f6ee2434266d3905be2d59 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 1.5E-61 T 22-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TOLA_RS03150 bca4000ce9f6ee2434266d3905be2d59 572 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 567 1.8E-270 T 22-04-2016 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS03150 bca4000ce9f6ee2434266d3905be2d59 572 PANTHER PTHR18968 2 572 0.0 T 22-04-2016 TOLA_RS03150 bca4000ce9f6ee2434266d3905be2d59 572 Gene3D G3DSA:3.40.50.970 2 177 2.9E-76 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS03150 bca4000ce9f6ee2434266d3905be2d59 572 PANTHER PTHR18968:SF116 2 572 0.0 T 22-04-2016 TOLA_RS03150 bca4000ce9f6ee2434266d3905be2d59 572 Gene3D G3DSA:3.40.50.970 358 555 8.3E-79 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS03150 bca4000ce9f6ee2434266d3905be2d59 572 SUPERFAMILY SSF52467 190 362 2.91E-63 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain TOLA_RS09680 671ec3c23b6fff9e3f28e73bcd3edb88 352 PANTHER PTHR30505 1 351 1.9E-145 T 22-04-2016 TOLA_RS09680 671ec3c23b6fff9e3f28e73bcd3edb88 352 Pfam PF02378 Phosphotransferase system, EIIC 17 279 1.5E-11 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS09680 671ec3c23b6fff9e3f28e73bcd3edb88 352 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 9 332 5.0E-86 T 22-04-2016 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 TOLA_RS09680 671ec3c23b6fff9e3f28e73bcd3edb88 352 PANTHER PTHR30505:SF1 1 351 1.9E-145 T 22-04-2016 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 Pfam PF00742 Homoserine dehydrogenase 614 810 1.8E-47 T 22-04-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 SUPERFAMILY SSF53633 1 298 1.23E-75 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 PANTHER PTHR21499:SF1 1 471 3.7E-156 T 22-04-2016 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 PIRSF PIRSF000727 1 817 0.0 T 22-04-2016 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I GO:0004072|GO:0004412|GO:0009067|GO:0055114 KEGG: 00260+1.1.1.3+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+1.1.1.3+2.7.2.4|KEGG: 00300+1.1.1.3+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00050|UniPathway: UPA00051|UniPathway: UPA00051 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 SUPERFAMILY SSF55347 614 797 1.44E-50 T 22-04-2016 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 22-04-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 Pfam PF13840 ACT domain 392 456 5.2E-8 T 22-04-2016 IPR027795 GATS-like ACT domain TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 SUPERFAMILY SSF55021 303 381 8.39E-22 T 22-04-2016 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 460 3.7E-135 T 22-04-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 Gene3D G3DSA:3.30.360.10 636 791 4.6E-55 T 22-04-2016 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 660 682 - T 22-04-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 Pfam PF00696 Amino acid kinase family 2 284 1.6E-46 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 Gene3D G3DSA:3.40.1160.10 111 299 9.0E-67 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 Gene3D G3DSA:3.40.1160.10 1 49 9.0E-67 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 Pfam PF01842 ACT domain 324 380 4.6E-8 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 472 606 8.3E-27 T 22-04-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 SUPERFAMILY SSF51735 463 636 1.35E-37 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 Gene3D G3DSA:3.40.50.720 464 635 3.3E-63 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 SUPERFAMILY SSF55021 385 475 3.05E-22 T 22-04-2016 TOLA_RS03210 1c9be8647f6458022c7df84cc3988fbc 819 PANTHER PTHR21499 1 471 3.7E-156 T 22-04-2016 TOLA_RS04870 432f7a94bcd2eb95733fab6e43469555 150 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 88 105 - T 22-04-2016 IPR000614 Free Met sulfoxide reductase conserved site TOLA_RS04870 432f7a94bcd2eb95733fab6e43469555 150 PANTHER PTHR21021 1 150 7.5E-57 T 22-04-2016 TOLA_RS04870 432f7a94bcd2eb95733fab6e43469555 150 SMART SM00065 21 149 0.0061 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS04870 432f7a94bcd2eb95733fab6e43469555 150 Pfam PF13185 GAF domain 41 141 5.1E-11 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS04870 432f7a94bcd2eb95733fab6e43469555 150 SUPERFAMILY SSF55781 6 141 5.02E-41 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS04870 432f7a94bcd2eb95733fab6e43469555 150 Gene3D G3DSA:3.30.450.40 7 145 8.8E-50 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS00565 7599e8d318865adc983b7bfb9f71f387 82 Pfam PF00366 Ribosomal protein S17 10 76 2.3E-32 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00565 7599e8d318865adc983b7bfb9f71f387 82 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 3 81 25.305 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00565 7599e8d318865adc983b7bfb9f71f387 82 PRINTS PR00973 Ribosomal protein S17 family signature 66 73 8.0E-11 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00565 7599e8d318865adc983b7bfb9f71f387 82 PRINTS PR00973 Ribosomal protein S17 family signature 56 66 8.0E-11 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00565 7599e8d318865adc983b7bfb9f71f387 82 PRINTS PR00973 Ribosomal protein S17 family signature 24 47 8.0E-11 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00565 7599e8d318865adc983b7bfb9f71f387 82 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 76 1.5E-37 T 22-04-2016 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00565 7599e8d318865adc983b7bfb9f71f387 82 SUPERFAMILY SSF50249 5 82 7.28E-33 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS00565 7599e8d318865adc983b7bfb9f71f387 82 PANTHER PTHR10744 4 82 3.4E-40 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00565 7599e8d318865adc983b7bfb9f71f387 82 ProSitePatterns PS00056 Ribosomal protein S17 signature. 56 68 - T 22-04-2016 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00565 7599e8d318865adc983b7bfb9f71f387 82 Gene3D G3DSA:2.40.50.140 6 82 7.9E-35 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS00565 7599e8d318865adc983b7bfb9f71f387 82 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 1 76 5.0E-30 T 22-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS16095 bcf40c50b2032042ff107831e203a344 156 Gene3D G3DSA:1.20.5.620 63 122 1.3E-21 T 22-04-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain TOLA_RS16095 bcf40c50b2032042ff107831e203a344 156 PANTHER PTHR33445 1 156 1.1E-46 T 22-04-2016 TOLA_RS16095 bcf40c50b2032042ff107831e203a344 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 137 3.1E-37 T 22-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TOLA_RS16095 bcf40c50b2032042ff107831e203a344 156 SUPERFAMILY SSF81573 63 121 7.32E-14 T 22-04-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain TOLA_RS16095 bcf40c50b2032042ff107831e203a344 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 156 13.216 T 22-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TOLA_RS16095 bcf40c50b2032042ff107831e203a344 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 156 1.7E-56 T 22-04-2016 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 TOLA_RS04875 1b48ecc04ec82ebeda3d5fa2cf7af80f 346 Pfam PF14321 Domain of unknown function (DUF4382) 31 210 6.0E-20 T 22-04-2016 IPR025491 Domain of unknown function DUF4382 TOLA_RS14070 4ec88af7487330cd17c19cc19263f267 405 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 13 400 44.944 T 22-04-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 TOLA_RS14070 4ec88af7487330cd17c19cc19263f267 405 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 222 259 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS14070 4ec88af7487330cd17c19cc19263f267 405 SUPERFAMILY SSF53383 3 399 2.55E-121 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS14070 4ec88af7487330cd17c19cc19263f267 405 PANTHER PTHR11986 12 405 6.4E-216 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS14070 4ec88af7487330cd17c19cc19263f267 405 Gene3D G3DSA:3.40.640.10 59 288 6.8E-92 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS14070 4ec88af7487330cd17c19cc19263f267 405 TIGRFAM TIGR03246 arg_catab_astC: succinylornithine transaminase family 7 403 4.3E-207 T 22-04-2016 IPR017652 Acetyl/Succinylornithine transaminase family, bacteria GO:0006520|GO:0008483|GO:0030170 TOLA_RS14070 4ec88af7487330cd17c19cc19263f267 405 Pfam PF00202 Aminotransferase class-III 25 397 1.1E-122 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS14070 4ec88af7487330cd17c19cc19263f267 405 PANTHER PTHR11986:SF71 12 405 6.4E-216 T 22-04-2016 TOLA_RS14070 4ec88af7487330cd17c19cc19263f267 405 Gene3D G3DSA:3.90.1150.10 289 402 6.2E-33 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS14070 4ec88af7487330cd17c19cc19263f267 405 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 16 398 8.4E-149 T 22-04-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 TOLA_RS06530 5595139c1516670a92452b5a55a33bc9 68 PIRSF PIRSF002599 1 68 4.2E-24 T 22-04-2016 IPR012156 Cold shock, CspA GO:0003676 TOLA_RS06530 5595139c1516670a92452b5a55a33bc9 68 PRINTS PR00050 Cold shock protein signature 41 59 7.0E-17 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOLA_RS06530 5595139c1516670a92452b5a55a33bc9 68 PRINTS PR00050 Cold shock protein signature 6 21 7.0E-17 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOLA_RS06530 5595139c1516670a92452b5a55a33bc9 68 PRINTS PR00050 Cold shock protein signature 26 35 7.0E-17 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOLA_RS06530 5595139c1516670a92452b5a55a33bc9 68 SUPERFAMILY SSF50249 4 67 3.05E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS06530 5595139c1516670a92452b5a55a33bc9 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 17 35 - T 22-04-2016 IPR019844 Cold-shock conserved site TOLA_RS06530 5595139c1516670a92452b5a55a33bc9 68 PANTHER PTHR11544 1 68 1.2E-38 T 22-04-2016 TOLA_RS06530 5595139c1516670a92452b5a55a33bc9 68 SMART SM00357 5 68 8.4E-31 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 TOLA_RS06530 5595139c1516670a92452b5a55a33bc9 68 Pfam PF00313 'Cold-shock' DNA-binding domain 5 67 7.4E-30 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOLA_RS06530 5595139c1516670a92452b5a55a33bc9 68 Gene3D G3DSA:2.40.50.140 5 67 1.2E-30 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS00960 98f005ea0cc0fe8b80566543262476d5 209 Gene3D G3DSA:3.30.63.10 50 89 6.3E-31 T 22-04-2016 TOLA_RS00960 98f005ea0cc0fe8b80566543262476d5 209 Gene3D G3DSA:3.40.50.300 90 203 4.1E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00960 98f005ea0cc0fe8b80566543262476d5 209 Gene3D G3DSA:3.40.50.300 3 15 4.1E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00960 98f005ea0cc0fe8b80566543262476d5 209 Hamap MF_00328 Guanylate kinase [gmk]. 3 189 36.99 T 22-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 TOLA_RS00960 98f005ea0cc0fe8b80566543262476d5 209 ProSitePatterns PS00856 Guanylate kinase-like signature. 42 59 - T 22-04-2016 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 TOLA_RS00960 98f005ea0cc0fe8b80566543262476d5 209 Gene3D G3DSA:3.40.50.300 16 49 4.9E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00960 98f005ea0cc0fe8b80566543262476d5 209 SUPERFAMILY SSF52540 5 189 2.42E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00960 98f005ea0cc0fe8b80566543262476d5 209 SMART SM00072 4 189 1.1E-69 T 22-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TOLA_RS00960 98f005ea0cc0fe8b80566543262476d5 209 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 186 1.1E-73 T 22-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 TOLA_RS00960 98f005ea0cc0fe8b80566543262476d5 209 PANTHER PTHR23117:SF13 1 206 9.0E-98 T 22-04-2016 TOLA_RS00960 98f005ea0cc0fe8b80566543262476d5 209 Pfam PF00625 Guanylate kinase 6 185 1.1E-58 T 22-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TOLA_RS00960 98f005ea0cc0fe8b80566543262476d5 209 PANTHER PTHR23117 1 206 9.0E-98 T 22-04-2016 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 SMART SM01210 330 423 4.3E-52 T 22-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 423 2.1E-182 T 22-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 Gene3D G3DSA:3.40.50.20 2 95 6.7E-38 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 SUPERFAMILY SSF51246 329 424 6.51E-31 T 22-04-2016 IPR011054 Rudiment single hybrid motif TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 SUPERFAMILY SSF52440 1 103 3.74E-37 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 3.0E-34 T 22-04-2016 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 Gene3D G3DSA:3.90.600.10 331 423 8.8E-34 T 22-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 331 421 5.8E-28 T 22-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 PANTHER PTHR10520 1 426 2.6E-292 T 22-04-2016 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 22-04-2016 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 Gene3D G3DSA:3.30.470.20 191 325 6.5E-63 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 Gene3D G3DSA:3.30.1490.20 121 190 2.7E-34 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 423 43.881 T 22-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 SUPERFAMILY SSF56059 104 322 9.55E-71 T 22-04-2016 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 2.9E-84 T 22-04-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 TOLA_RS02790 f810f611bd201c4d5e12d21ad0603a32 428 SMART SM01209 103 296 5.6E-145 T 22-04-2016 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PRINTS PR01466 Bacterial arginine deiminase signature 345 362 2.8E-47 T 22-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PRINTS PR01466 Bacterial arginine deiminase signature 179 194 2.8E-47 T 22-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PRINTS PR01466 Bacterial arginine deiminase signature 388 406 2.8E-47 T 22-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PRINTS PR01466 Bacterial arginine deiminase signature 4 24 2.8E-47 T 22-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PRINTS PR01466 Bacterial arginine deiminase signature 151 169 2.8E-47 T 22-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PRINTS PR01466 Bacterial arginine deiminase signature 365 379 2.8E-47 T 22-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 SUPERFAMILY SSF55909 6 407 1.71E-125 T 22-04-2016 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PIRSF PIRSF006356 1 409 9.7E-132 T 22-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 Pfam PF02274 Amidinotransferase 20 406 6.5E-92 T 22-04-2016 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PANTHER PTHR12737:SF13 314 409 9.9E-114 T 22-04-2016 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PANTHER PTHR12737:SF13 1 93 9.9E-114 T 22-04-2016 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PANTHER PTHR12737:SF13 151 292 9.9E-114 T 22-04-2016 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 Gene3D G3DSA:3.75.10.10 151 409 2.6E-122 T 22-04-2016 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 Gene3D G3DSA:3.75.10.10 2 69 2.6E-122 T 22-04-2016 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PANTHER PTHR12737 314 409 9.9E-114 T 22-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PANTHER PTHR12737 1 93 9.9E-114 T 22-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 PANTHER PTHR12737 151 292 9.9E-114 T 22-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 TOLA_RS12510 33e0aece115622f58fbb76d539abb1a7 409 Hamap MF_00242 Arginine deiminase [arcA]. 3 409 46.564 T 22-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 TOLA_RS02580 a7ffd3e5fdbc3e4cddcf365de3961ae2 242 Pfam PF00849 RNA pseudouridylate synthase 11 172 3.1E-31 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS02580 a7ffd3e5fdbc3e4cddcf365de3961ae2 242 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 51 65 - T 22-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS02580 a7ffd3e5fdbc3e4cddcf365de3961ae2 242 PANTHER PTHR11079:SF60 4 241 3.3E-78 T 22-04-2016 TOLA_RS02580 a7ffd3e5fdbc3e4cddcf365de3961ae2 242 SUPERFAMILY SSF55120 2 240 2.08E-61 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS02580 a7ffd3e5fdbc3e4cddcf365de3961ae2 242 PANTHER PTHR11079 4 241 3.3E-78 T 22-04-2016 TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.5E-39 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.5E-39 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.5E-39 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.5E-39 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.5E-39 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.5E-39 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PANTHER PTHR24322 14 142 8.1E-54 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PANTHER PTHR24322 158 190 8.1E-54 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 Gene3D G3DSA:3.40.50.720 4 252 2.0E-83 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 SUPERFAMILY SSF51735 9 252 2.79E-79 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 Pfam PF00106 short chain dehydrogenase 10 203 5.6E-63 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 8.9E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 8.9E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 8.9E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PANTHER PTHR24322:SF459 14 142 8.1E-54 T 22-04-2016 TOLA_RS01195 8df4f82042da2b78f0eec3086991d1cc 254 PANTHER PTHR24322:SF459 158 190 8.1E-54 T 22-04-2016 TOLA_RS14035 c6be80b998b0847cb6edfabb22185cec 440 PANTHER PTHR11061:SF30 15 440 8.1E-111 T 22-04-2016 TOLA_RS14035 c6be80b998b0847cb6edfabb22185cec 440 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 256 432 1.2E-56 T 22-04-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 TOLA_RS14035 c6be80b998b0847cb6edfabb22185cec 440 Pfam PF01938 TRAM domain 15 66 2.1E-10 T 22-04-2016 IPR002792 TRAM domain TOLA_RS14035 c6be80b998b0847cb6edfabb22185cec 440 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 422 432 - T 22-04-2016 IPR030391 RNA methyltransferase TrmA, conserved site TOLA_RS14035 c6be80b998b0847cb6edfabb22185cec 440 SUPERFAMILY SSF53335 75 439 4.07E-77 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS14035 c6be80b998b0847cb6edfabb22185cec 440 Gene3D G3DSA:3.40.50.150 253 439 4.3E-54 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS14035 c6be80b998b0847cb6edfabb22185cec 440 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 268 439 3.9E-22 T 22-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TOLA_RS14035 c6be80b998b0847cb6edfabb22185cec 440 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 18 440 65.227 T 22-04-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 TOLA_RS14035 c6be80b998b0847cb6edfabb22185cec 440 PANTHER PTHR11061 15 440 8.1E-111 T 22-04-2016 TOLA_RS14035 c6be80b998b0847cb6edfabb22185cec 440 SUPERFAMILY SSF50249 4 66 2.34E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS14035 c6be80b998b0847cb6edfabb22185cec 440 Gene3D G3DSA:2.40.50.140 2 87 1.3E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS06020 959aece60135f8ef567210d4bd250901 383 Gene3D G3DSA:3.40.50.1970 2 184 1.2E-51 T 22-04-2016 TOLA_RS06020 959aece60135f8ef567210d4bd250901 383 PANTHER PTHR11496 1 382 1.2E-171 T 22-04-2016 TOLA_RS06020 959aece60135f8ef567210d4bd250901 383 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 260 280 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS06020 959aece60135f8ef567210d4bd250901 383 PANTHER PTHR11496:SF74 1 382 1.2E-171 T 22-04-2016 TOLA_RS06020 959aece60135f8ef567210d4bd250901 383 Gene3D G3DSA:1.20.1090.10 185 383 4.4E-71 T 22-04-2016 TOLA_RS06020 959aece60135f8ef567210d4bd250901 383 SUPERFAMILY SSF56796 3 382 3.53E-119 T 22-04-2016 TOLA_RS06020 959aece60135f8ef567210d4bd250901 383 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS06020 959aece60135f8ef567210d4bd250901 383 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 374 1.1E-113 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 TOLA_RS02495 ea114568d3c909857f67b8e2ae8f352d 70 PANTHER PTHR33280 1 66 2.5E-36 T 22-04-2016 TOLA_RS02495 ea114568d3c909857f67b8e2ae8f352d 70 SUPERFAMILY SSF143800 1 66 6.28E-28 T 22-04-2016 TOLA_RS02495 ea114568d3c909857f67b8e2ae8f352d 70 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS02495 ea114568d3c909857f67b8e2ae8f352d 70 PRINTS PR01249 Ribosomal protein L31 signature 30 45 1.0E-23 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS02495 ea114568d3c909857f67b8e2ae8f352d 70 PRINTS PR01249 Ribosomal protein L31 signature 45 63 1.0E-23 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS02495 ea114568d3c909857f67b8e2ae8f352d 70 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.0E-23 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS02495 ea114568d3c909857f67b8e2ae8f352d 70 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 64 2.4E-34 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS02495 ea114568d3c909857f67b8e2ae8f352d 70 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 67 30.47 T 22-04-2016 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS02495 ea114568d3c909857f67b8e2ae8f352d 70 Pfam PF01197 Ribosomal protein L31 1 64 3.0E-33 T 22-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS11065 d54067d608caceba5d5595e764ddad36 362 Pfam PF01264 Chorismate synthase 10 345 5.4E-141 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS11065 d54067d608caceba5d5595e764ddad36 362 Gene3D G3DSA:3.60.150.10 9 351 1.6E-157 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS11065 d54067d608caceba5d5595e764ddad36 362 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 1.3E-141 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS11065 d54067d608caceba5d5595e764ddad36 362 PANTHER PTHR21085 2 352 1.1E-216 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS11065 d54067d608caceba5d5595e764ddad36 362 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS11065 d54067d608caceba5d5595e764ddad36 362 PIRSF PIRSF001456 3 361 4.9E-140 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS11065 d54067d608caceba5d5595e764ddad36 362 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS11065 d54067d608caceba5d5595e764ddad36 362 SUPERFAMILY SSF103263 4 352 1.31E-148 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS11065 d54067d608caceba5d5595e764ddad36 362 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 37.47 T 22-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS11065 d54067d608caceba5d5595e764ddad36 362 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 22-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS11875 4c89ffc67bebf5f602505ca95ce62087 86 Gene3D G3DSA:3.10.20.280 1 75 1.2E-20 T 22-04-2016 IPR005346 RnfH protein TOLA_RS11875 4c89ffc67bebf5f602505ca95ce62087 86 PANTHER PTHR37483:SF1 1 73 5.3E-14 T 22-04-2016 TOLA_RS11875 4c89ffc67bebf5f602505ca95ce62087 86 SUPERFAMILY SSF54285 1 74 2.03E-20 T 22-04-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TOLA_RS11875 4c89ffc67bebf5f602505ca95ce62087 86 Hamap MF_00460 Protein RnfH [rnfH]. 1 83 15.918 T 22-04-2016 IPR005346 RnfH protein TOLA_RS11875 4c89ffc67bebf5f602505ca95ce62087 86 PANTHER PTHR37483 1 73 5.3E-14 T 22-04-2016 TOLA_RS11875 4c89ffc67bebf5f602505ca95ce62087 86 Pfam PF03658 RnfH family Ubiquitin 1 79 6.3E-23 T 22-04-2016 IPR005346 RnfH protein TOLA_RS01995 eeb271f9d81127b49010e383cff20798 457 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 406 422 - T 22-04-2016 IPR031312 Sodium/sulphate symporter, conserved site TOLA_RS01995 eeb271f9d81127b49010e383cff20798 457 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 35 452 4.5E-118 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 TOLA_RS01995 eeb271f9d81127b49010e383cff20798 457 PANTHER PTHR10283 6 451 9.5E-116 T 22-04-2016 TOLA_RS01995 eeb271f9d81127b49010e383cff20798 457 PANTHER PTHR10283:SF82 6 451 9.5E-116 T 22-04-2016 TOLA_RS01995 eeb271f9d81127b49010e383cff20798 457 Pfam PF00939 Sodium:sulfate symporter transmembrane region 38 452 4.3E-56 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 TOLA_RS12710 48293d4bdec0843f2af09b05db96bd43 225 Pfam PF13394 4Fe-4S single cluster domain 27 131 1.5E-11 T 22-04-2016 TOLA_RS12710 48293d4bdec0843f2af09b05db96bd43 225 Gene3D G3DSA:3.20.20.70 32 125 6.1E-7 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS12710 48293d4bdec0843f2af09b05db96bd43 225 Pfam PF04055 Radical SAM superfamily 29 127 2.6E-8 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS12710 48293d4bdec0843f2af09b05db96bd43 225 TIGRFAM TIGR04322 rSAM_QueE_Ecoli: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 12 225 4.0E-106 T 22-04-2016 IPR027609 Putative 7-carboxy-7-deazaguanine synthase QueE, Proteobacteria KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 TOLA_RS12710 48293d4bdec0843f2af09b05db96bd43 225 PANTHER PTHR11228:SF6 75 224 4.7E-44 T 22-04-2016 TOLA_RS12710 48293d4bdec0843f2af09b05db96bd43 225 PANTHER PTHR11228:SF6 1 59 4.7E-44 T 22-04-2016 TOLA_RS12710 48293d4bdec0843f2af09b05db96bd43 225 PANTHER PTHR11228 75 224 4.7E-44 T 22-04-2016 TOLA_RS12710 48293d4bdec0843f2af09b05db96bd43 225 PANTHER PTHR11228 1 59 4.7E-44 T 22-04-2016 TOLA_RS12710 48293d4bdec0843f2af09b05db96bd43 225 SUPERFAMILY SSF102114 27 122 6.08E-6 T 22-04-2016 TOLA_RS12710 48293d4bdec0843f2af09b05db96bd43 225 PIRSF PIRSF000370 4 225 8.2E-64 T 22-04-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 TOLA_RS12710 48293d4bdec0843f2af09b05db96bd43 225 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 6 225 35.53 T 22-04-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 TOLA_RS01760 6b1d154f32320b9dcda9cc8843596169 247 PANTHER PTHR10108:SF864 5 247 8.6E-173 T 22-04-2016 TOLA_RS01760 6b1d154f32320b9dcda9cc8843596169 247 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 21 246 1.6E-88 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 TOLA_RS01760 6b1d154f32320b9dcda9cc8843596169 247 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 12 246 39.587 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 TOLA_RS01760 6b1d154f32320b9dcda9cc8843596169 247 PANTHER PTHR10108 5 247 8.6E-173 T 22-04-2016 TOLA_RS01760 6b1d154f32320b9dcda9cc8843596169 247 Gene3D G3DSA:3.40.50.150 21 243 1.7E-58 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS01760 6b1d154f32320b9dcda9cc8843596169 247 Pfam PF01209 ubiE/COQ5 methyltransferase family 16 246 3.9E-103 T 22-04-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 TOLA_RS01760 6b1d154f32320b9dcda9cc8843596169 247 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 32 47 - T 22-04-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 TOLA_RS01760 6b1d154f32320b9dcda9cc8843596169 247 SUPERFAMILY SSF53335 15 244 2.94E-51 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS01510 65bb996519bff2c1aaf67d376a2d5787 581 Gene3D G3DSA:3.40.50.2300 1 101 5.0E-27 T 22-04-2016 TOLA_RS01510 65bb996519bff2c1aaf67d376a2d5787 581 Gene3D G3DSA:3.40.50.2300 121 224 1.4E-43 T 22-04-2016 TOLA_RS01510 65bb996519bff2c1aaf67d376a2d5787 581 SUPERFAMILY SSF52794 2 99 3.31E-26 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS01510 65bb996519bff2c1aaf67d376a2d5787 581 PANTHER PTHR30505:SF0 1 572 5.0E-256 T 22-04-2016 TOLA_RS01510 65bb996519bff2c1aaf67d376a2d5787 581 Pfam PF02378 Phosphotransferase system, EIIC 251 517 2.8E-16 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS01510 65bb996519bff2c1aaf67d376a2d5787 581 SUPERFAMILY SSF52794 124 222 1.24E-36 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS01510 65bb996519bff2c1aaf67d376a2d5787 581 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 93 4.2E-14 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS01510 65bb996519bff2c1aaf67d376a2d5787 581 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 127 212 1.4E-19 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS01510 65bb996519bff2c1aaf67d376a2d5787 581 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 236 573 5.6E-132 T 22-04-2016 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 TOLA_RS01510 65bb996519bff2c1aaf67d376a2d5787 581 PANTHER PTHR30505 1 572 5.0E-256 T 22-04-2016 TOLA_RS01510 65bb996519bff2c1aaf67d376a2d5787 581 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 126 209 1.6E-39 T 22-04-2016 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 TOLA_RS02940 f762544573673442d6c601053fc83310 139 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 139 31.378 T 22-04-2016 IPR023064 D-ribose pyranase GO:0016872 UniPathway: UPA00916 TOLA_RS02940 f762544573673442d6c601053fc83310 139 PANTHER PTHR37831 2 139 3.8E-59 T 22-04-2016 TOLA_RS02940 f762544573673442d6c601053fc83310 139 SUPERFAMILY SSF102546 1 139 3.4E-41 T 22-04-2016 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 TOLA_RS02940 f762544573673442d6c601053fc83310 139 PANTHER PTHR37831:SF1 2 139 3.8E-59 T 22-04-2016 TOLA_RS02940 f762544573673442d6c601053fc83310 139 Gene3D G3DSA:3.40.1650.10 1 139 1.2E-38 T 22-04-2016 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 TOLA_RS02940 f762544573673442d6c601053fc83310 139 Pfam PF05025 RbsD / FucU transport protein family 1 138 2.6E-47 T 22-04-2016 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 TOLA_RS11440 cde42fa96ccdd3b4c591c800f529f79a 644 Pfam PF01434 Peptidase family M41 385 594 1.6E-83 T 22-04-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 TOLA_RS11440 cde42fa96ccdd3b4c591c800f529f79a 644 PANTHER PTHR23076 3 596 0.0 T 22-04-2016 TOLA_RS11440 cde42fa96ccdd3b4c591c800f529f79a 644 Gene3D G3DSA:3.40.50.300 151 334 1.9E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11440 cde42fa96ccdd3b4c591c800f529f79a 644 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 191 323 5.3E-45 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS11440 cde42fa96ccdd3b4c591c800f529f79a 644 SUPERFAMILY SSF140990 405 602 1.96E-75 T 22-04-2016 TOLA_RS11440 cde42fa96ccdd3b4c591c800f529f79a 644 SUPERFAMILY SSF52540 148 394 3.81E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11440 cde42fa96ccdd3b4c591c800f529f79a 644 Pfam PF06480 FtsH Extracellular 8 89 4.1E-10 T 22-04-2016 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 TOLA_RS11440 cde42fa96ccdd3b4c591c800f529f79a 644 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 609 37.505 T 22-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 TOLA_RS11440 cde42fa96ccdd3b4c591c800f529f79a 644 SMART SM00382 187 326 3.3E-25 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS11440 cde42fa96ccdd3b4c591c800f529f79a 644 ProSitePatterns PS00674 AAA-protein family signature. 294 312 - T 22-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TOLA_RS11440 cde42fa96ccdd3b4c591c800f529f79a 644 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 103 596 1.4E-244 T 22-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 TOLA_RS11440 cde42fa96ccdd3b4c591c800f529f79a 644 Gene3D G3DSA:1.10.8.60 335 408 5.4E-29 T 22-04-2016 TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 6.7E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 6.7E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 6.7E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 Gene3D G3DSA:3.40.50.2300 2 120 3.3E-34 T 22-04-2016 TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 Gene3D G3DSA:1.10.10.10 121 211 1.7E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 SUPERFAMILY SSF52172 3 131 1.57E-34 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 Pfam PF00072 Response regulator receiver domain 4 116 7.6E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 PANTHER PTHR26402 2 215 2.5E-94 T 22-04-2016 TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 SUPERFAMILY SSF46894 132 211 7.82E-19 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 SMART SM00421 147 204 6.1E-17 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 SMART SM00448 2 115 1.7E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 PANTHER PTHR26402:SF506 2 215 2.5E-94 T 22-04-2016 TOLA_RS07875 1fb068dcde1c521f499acca988902c58 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 5.3E-19 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS05740 0b3321f7d13727a6239f311d8f4d6510 472 Pfam PF00929 Exonuclease 12 191 9.0E-22 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III TOLA_RS05740 0b3321f7d13727a6239f311d8f4d6510 472 PIRSF PIRSF000977 2 471 7.8E-191 T 22-04-2016 IPR023607 Exodeoxyribonuclease I GO:0004529 TOLA_RS05740 0b3321f7d13727a6239f311d8f4d6510 472 Gene3D G3DSA:3.30.420.10 3 199 1.2E-81 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS05740 0b3321f7d13727a6239f311d8f4d6510 472 SUPERFAMILY SSF53098 9 460 5.96E-128 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS05740 0b3321f7d13727a6239f311d8f4d6510 472 PANTHER PTHR11046 5 450 3.4E-244 T 22-04-2016 TOLA_RS05740 0b3321f7d13727a6239f311d8f4d6510 472 PANTHER PTHR11046:SF2 5 450 3.4E-244 T 22-04-2016 IPR023607 Exodeoxyribonuclease I GO:0004529 TOLA_RS05740 0b3321f7d13727a6239f311d8f4d6510 472 Pfam PF08411 Exonuclease C-terminal 211 470 6.4E-96 T 22-04-2016 IPR013620 Exonuclease C-terminal GO:0006281|GO:0008852 TOLA_RS13955 a4a789acad0e0ed09ffe0e70e489f191 151 Gene3D G3DSA:1.10.10.10 103 146 3.1E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13955 a4a789acad0e0ed09ffe0e70e489f191 151 PANTHER PTHR33602 12 146 5.2E-34 T 22-04-2016 TOLA_RS13955 a4a789acad0e0ed09ffe0e70e489f191 151 Gene3D G3DSA:1.10.10.10 12 56 1.0E-12 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13955 a4a789acad0e0ed09ffe0e70e489f191 151 Gene3D G3DSA:1.10.10.10 57 101 2.1E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13955 a4a789acad0e0ed09ffe0e70e489f191 151 Hamap MF_01114 Regulatory protein RecX [recX]. 7 151 13.326 T 22-04-2016 IPR003783 Regulatory protein RecX GO:0006282 TOLA_RS13955 a4a789acad0e0ed09ffe0e70e489f191 151 Pfam PF02631 RecX family 37 146 2.8E-31 T 22-04-2016 IPR003783 Regulatory protein RecX GO:0006282 TOLA_RS13955 a4a789acad0e0ed09ffe0e70e489f191 151 PANTHER PTHR33602:SF1 12 146 5.2E-34 T 22-04-2016 TOLA_RS07985 e2d1ba0bec0fe467fe7705f1c2e875bd 418 Gene3D G3DSA:3.40.1190.10 11 285 2.6E-90 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS07985 e2d1ba0bec0fe467fe7705f1c2e875bd 418 PANTHER PTHR11136:SF0 11 413 3.3E-127 T 22-04-2016 TOLA_RS07985 e2d1ba0bec0fe467fe7705f1c2e875bd 418 Gene3D G3DSA:3.90.190.20 287 417 5.0E-41 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS07985 e2d1ba0bec0fe467fe7705f1c2e875bd 418 Pfam PF08245 Mur ligase middle domain 53 227 4.1E-11 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS07985 e2d1ba0bec0fe467fe7705f1c2e875bd 418 SUPERFAMILY SSF53244 286 413 4.88E-31 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS07985 e2d1ba0bec0fe467fe7705f1c2e875bd 418 Pfam PF02875 Mur ligase family, glutamate ligase domain 287 337 1.4E-6 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS07985 e2d1ba0bec0fe467fe7705f1c2e875bd 418 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 143 158 - T 22-04-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 TOLA_RS07985 e2d1ba0bec0fe467fe7705f1c2e875bd 418 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 51 74 - T 22-04-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 TOLA_RS07985 e2d1ba0bec0fe467fe7705f1c2e875bd 418 PIRSF PIRSF001563 5 418 1.6E-113 T 22-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 TOLA_RS07985 e2d1ba0bec0fe467fe7705f1c2e875bd 418 PANTHER PTHR11136 11 413 3.3E-127 T 22-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 TOLA_RS07985 e2d1ba0bec0fe467fe7705f1c2e875bd 418 TIGRFAM TIGR01499 folC: bifunctional protein FolC 31 413 1.3E-104 T 22-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 TOLA_RS07985 e2d1ba0bec0fe467fe7705f1c2e875bd 418 SUPERFAMILY SSF53623 10 284 4.58E-88 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS10800 5f6c551e5b1d28e8f56c444621b0595c 176 Pfam PF00583 Acetyltransferase (GNAT) family 77 150 1.9E-10 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS10800 5f6c551e5b1d28e8f56c444621b0595c 176 PANTHER PTHR23091 26 176 4.2E-18 T 22-04-2016 TOLA_RS10800 5f6c551e5b1d28e8f56c444621b0595c 176 SUPERFAMILY SSF55729 33 172 2.79E-21 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS10800 5f6c551e5b1d28e8f56c444621b0595c 176 Gene3D G3DSA:3.40.630.30 33 172 7.4E-20 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS05235 4a7d8086ea85838aedb965e61a0f3441 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.5E-6 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS05235 4a7d8086ea85838aedb965e61a0f3441 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.5E-6 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS05235 4a7d8086ea85838aedb965e61a0f3441 338 Gene3D G3DSA:3.40.50.2300 55 172 1.1E-28 T 22-04-2016 TOLA_RS05235 4a7d8086ea85838aedb965e61a0f3441 338 Pfam PF13377 Periplasmic binding protein-like domain 169 330 7.2E-26 T 22-04-2016 TOLA_RS05235 4a7d8086ea85838aedb965e61a0f3441 338 Gene3D G3DSA:1.10.260.40 1 46 1.1E-22 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS05235 4a7d8086ea85838aedb965e61a0f3441 338 Gene3D G3DSA:3.40.50.2300 173 306 8.6E-29 T 22-04-2016 TOLA_RS05235 4a7d8086ea85838aedb965e61a0f3441 338 SUPERFAMILY SSF47413 1 47 1.45E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS05235 4a7d8086ea85838aedb965e61a0f3441 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS05235 4a7d8086ea85838aedb965e61a0f3441 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 46 2.0E-20 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS05235 4a7d8086ea85838aedb965e61a0f3441 338 SUPERFAMILY SSF53822 66 330 1.28E-46 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS05235 4a7d8086ea85838aedb965e61a0f3441 338 SMART SM00354 1 74 4.1E-20 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS05235 4a7d8086ea85838aedb965e61a0f3441 338 PANTHER PTHR30146 1 332 1.8E-76 T 22-04-2016 TOLA_RS10395 3c0ae1fbe473498cdf5a23f0e7bfa7db 316 PANTHER PTHR22916:SF22 12 312 1.6E-94 T 22-04-2016 TOLA_RS10395 3c0ae1fbe473498cdf5a23f0e7bfa7db 316 PANTHER PTHR22916 12 312 1.6E-94 T 22-04-2016 TOLA_RS10395 3c0ae1fbe473498cdf5a23f0e7bfa7db 316 SUPERFAMILY SSF53448 253 274 7.5E-41 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS10395 3c0ae1fbe473498cdf5a23f0e7bfa7db 316 SUPERFAMILY SSF53448 11 222 7.5E-41 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS10395 3c0ae1fbe473498cdf5a23f0e7bfa7db 316 Gene3D G3DSA:3.90.550.10 13 231 2.3E-26 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS10395 3c0ae1fbe473498cdf5a23f0e7bfa7db 316 Pfam PF13641 Glycosyltransferase like family 2 13 229 5.0E-18 T 22-04-2016 TOLA_RS04985 9e755e3176639a6809d240e08c080a24 438 Gene3D G3DSA:3.40.50.300 205 370 2.3E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04985 9e755e3176639a6809d240e08c080a24 438 SMART SM00490 259 340 1.8E-34 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS04985 9e755e3176639a6809d240e08c080a24 438 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TOLA_RS04985 9e755e3176639a6809d240e08c080a24 438 PANTHER PTHR24031:SF334 2 419 4.9E-180 T 22-04-2016 TOLA_RS04985 9e755e3176639a6809d240e08c080a24 438 Pfam PF00270 DEAD/DEAH box helicase 25 195 3.3E-48 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS04985 9e755e3176639a6809d240e08c080a24 438 Pfam PF00271 Helicase conserved C-terminal domain 232 340 7.1E-33 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS04985 9e755e3176639a6809d240e08c080a24 438 SUPERFAMILY SSF52540 74 361 1.58E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04985 9e755e3176639a6809d240e08c080a24 438 Gene3D G3DSA:3.40.50.300 1 204 1.3E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04985 9e755e3176639a6809d240e08c080a24 438 Hamap MF_00967 ATP-dependent RNA helicase SrmB [srmB]. 1 417 51.023 T 22-04-2016 IPR028621 ATP-dependent RNA helicase SrmB GO:0000027|GO:0004004 TOLA_RS04985 9e755e3176639a6809d240e08c080a24 438 PANTHER PTHR24031 2 419 4.9E-180 T 22-04-2016 TOLA_RS04985 9e755e3176639a6809d240e08c080a24 438 SMART SM00487 20 220 2.6E-55 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS11125 62fde25bcb04df867e0d9852f1f755e7 78 PANTHER PTHR20863 4 78 1.4E-30 T 22-04-2016 TOLA_RS11125 62fde25bcb04df867e0d9852f1f755e7 78 SUPERFAMILY SSF47336 2 77 2.36E-23 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain TOLA_RS11125 62fde25bcb04df867e0d9852f1f755e7 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 77 1.6E-36 T 22-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 TOLA_RS11125 62fde25bcb04df867e0d9852f1f755e7 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 21.935 T 22-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 TOLA_RS11125 62fde25bcb04df867e0d9852f1f755e7 78 Gene3D G3DSA:1.10.1200.10 3 77 3.0E-35 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain TOLA_RS11125 62fde25bcb04df867e0d9852f1f755e7 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 22-04-2016 IPR006162 Phosphopantetheine attachment site TOLA_RS11125 62fde25bcb04df867e0d9852f1f755e7 78 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.2E-15 T 22-04-2016 IPR009081 Phosphopantetheine binding ACP domain TOLA_RS13425 1a0adfae32c3352dd465d158cc423589 506 PANTHER PTHR24220:SF303 15 388 6.0E-278 T 22-04-2016 TOLA_RS13425 1a0adfae32c3352dd465d158cc423589 506 Pfam PF00005 ABC transporter 29 178 1.1E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS13425 1a0adfae32c3352dd465d158cc423589 506 Pfam PF00005 ABC transporter 280 434 2.6E-19 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS13425 1a0adfae32c3352dd465d158cc423589 506 PANTHER PTHR24220 15 388 6.0E-278 T 22-04-2016 TOLA_RS13425 1a0adfae32c3352dd465d158cc423589 506 SUPERFAMILY SSF52540 12 236 1.52E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13425 1a0adfae32c3352dd465d158cc423589 506 Gene3D G3DSA:3.40.50.300 10 239 2.4E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13425 1a0adfae32c3352dd465d158cc423589 506 Gene3D G3DSA:3.40.50.300 265 498 2.6E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13425 1a0adfae32c3352dd465d158cc423589 506 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS13425 1a0adfae32c3352dd465d158cc423589 506 SMART SM00382 288 483 0.24 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS13425 1a0adfae32c3352dd465d158cc423589 506 SMART SM00382 38 225 1.4E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS13425 1a0adfae32c3352dd465d158cc423589 506 SUPERFAMILY SSF52540 253 487 1.43E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 SUPERFAMILY SSF52540 209 473 4.07E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 SUPERFAMILY SSF52540 137 167 4.07E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 PIRSF PIRSF006485 1 475 1.1E-178 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 Pfam PF01926 50S ribosome-binding GTPase 214 331 1.1E-23 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 Pfam PF01926 50S ribosome-binding GTPase 5 119 5.8E-28 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 2.8E-9 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.8E-9 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 Gene3D G3DSA:3.30.300.20 393 468 1.7E-23 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 387 466 9.0E-26 T 22-04-2016 IPR032859 GTPase Der, C-terminal KH-domain-like TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 SUPERFAMILY SSF52540 4 165 1.15E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 PANTHER PTHR11649:SF5 1 474 6.2E-157 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 212 377 2.2E-23 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 154 1.8E-19 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 Gene3D G3DSA:3.40.50.300 211 392 1.6E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 Gene3D G3DSA:3.40.50.300 3 164 9.2E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 467 2.8E-178 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 PANTHER PTHR11649 1 474 6.2E-157 T 22-04-2016 TOLA_RS04575 a070f0cfe2e806858eac256aab2c6b68 498 Hamap MF_00195 GTPase Der [der]. 2 470 38.639 T 22-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 TOLA_RS08510 288dc551039d2fbd25913b4ab4dd6a2f 241 PANTHER PTHR21091:SF9 1 167 1.3E-53 T 22-04-2016 TOLA_RS08510 288dc551039d2fbd25913b4ab4dd6a2f 241 Gene3D G3DSA:3.40.1010.10 1 112 8.8E-32 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 TOLA_RS08510 288dc551039d2fbd25913b4ab4dd6a2f 241 Gene3D G3DSA:3.30.950.10 113 226 1.5E-13 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 TOLA_RS08510 288dc551039d2fbd25913b4ab4dd6a2f 241 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 2 240 6.3E-105 T 22-04-2016 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 TOLA_RS08510 288dc551039d2fbd25913b4ab4dd6a2f 241 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 208 2.8E-40 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS08510 288dc551039d2fbd25913b4ab4dd6a2f 241 PANTHER PTHR21091 1 167 1.3E-53 T 22-04-2016 TOLA_RS08510 288dc551039d2fbd25913b4ab4dd6a2f 241 SUPERFAMILY SSF53790 1 239 4.58E-56 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS14925 4bec3a4e91edc14dd331d9494484d210 473 Pfam PF01235 Sodium:alanine symporter family 49 451 2.1E-161 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS14925 4bec3a4e91edc14dd331d9494484d210 473 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 440 1.9E-161 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS14925 4bec3a4e91edc14dd331d9494484d210 473 PANTHER PTHR30330 1 472 6.6E-286 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS14925 4bec3a4e91edc14dd331d9494484d210 473 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 86 101 - T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS14925 4bec3a4e91edc14dd331d9494484d210 473 PRINTS PR00175 Sodium/alanine symporter signature 348 370 2.8E-59 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS14925 4bec3a4e91edc14dd331d9494484d210 473 PRINTS PR00175 Sodium/alanine symporter signature 86 108 2.8E-59 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS14925 4bec3a4e91edc14dd331d9494484d210 473 PRINTS PR00175 Sodium/alanine symporter signature 177 195 2.8E-59 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS14925 4bec3a4e91edc14dd331d9494484d210 473 PRINTS PR00175 Sodium/alanine symporter signature 302 320 2.8E-59 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS14925 4bec3a4e91edc14dd331d9494484d210 473 PRINTS PR00175 Sodium/alanine symporter signature 205 224 2.8E-59 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS14925 4bec3a4e91edc14dd331d9494484d210 473 PRINTS PR00175 Sodium/alanine symporter signature 409 429 2.8E-59 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS14925 4bec3a4e91edc14dd331d9494484d210 473 PANTHER PTHR30330:SF1 1 472 6.6E-286 T 22-04-2016 TOLA_RS00730 e8ccf62fcf412d5a61c8500911cc9a3c 235 SMART SM00382 26 214 8.8E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS00730 e8ccf62fcf412d5a61c8500911cc9a3c 235 PANTHER PTHR24220:SF568 3 234 7.5E-135 T 22-04-2016 TOLA_RS00730 e8ccf62fcf412d5a61c8500911cc9a3c 235 PANTHER PTHR24220 3 234 7.5E-135 T 22-04-2016 TOLA_RS00730 e8ccf62fcf412d5a61c8500911cc9a3c 235 Gene3D G3DSA:3.40.50.300 1 231 3.7E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00730 e8ccf62fcf412d5a61c8500911cc9a3c 235 SUPERFAMILY SSF52540 2 233 8.95E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00730 e8ccf62fcf412d5a61c8500911cc9a3c 235 PIRSF PIRSF039137 1 235 3.7E-104 T 22-04-2016 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 TOLA_RS00730 e8ccf62fcf412d5a61c8500911cc9a3c 235 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS00730 e8ccf62fcf412d5a61c8500911cc9a3c 235 Pfam PF00005 ABC transporter 17 162 8.5E-34 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS02785 ca12ddd76e9bd6e6c497b3efec83801d 147 Pfam PF13633 Prokaryotic N-terminal methylation site 4 30 1.6E-12 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS02785 ca12ddd76e9bd6e6c497b3efec83801d 147 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS02785 ca12ddd76e9bd6e6c497b3efec83801d 147 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 6.7E-10 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS02785 ca12ddd76e9bd6e6c497b3efec83801d 147 SUPERFAMILY SSF54523 7 136 1.1E-23 T 22-04-2016 TOLA_RS02785 ca12ddd76e9bd6e6c497b3efec83801d 147 PANTHER PTHR30093 1 63 1.2E-23 T 22-04-2016 TOLA_RS02785 ca12ddd76e9bd6e6c497b3efec83801d 147 Gene3D G3DSA:3.30.700.10 7 140 1.8E-27 T 22-04-2016 TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 51 74 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 PANTHER PTHR10584:SF159 1 340 4.4E-135 T 22-04-2016 TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 SUPERFAMILY SSF53613 12 311 4.83E-62 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 Hamap MF_01603 Bifunctional protein HldE [hldE]. 4 476 42.159 T 22-04-2016 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167|UniPathway: UPA00356|UniPathway: UPA00356 TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 PANTHER PTHR10584 1 340 4.4E-135 T 22-04-2016 TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 Pfam PF00294 pfkB family carbohydrate kinase 12 305 3.7E-52 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 Pfam PF01467 Cytidylyltransferase-like 347 437 1.4E-14 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 6 312 1.3E-125 T 22-04-2016 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167|UniPathway: UPA00356|UniPathway: UPA00356 TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 SUPERFAMILY SSF52374 342 472 7.04E-22 T 22-04-2016 TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 258 271 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 336 473 1.0E-61 T 22-04-2016 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167|UniPathway: UPA00356|UniPathway: UPA00356 TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 Gene3D G3DSA:3.40.50.620 342 463 8.5E-37 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 344 410 1.4E-17 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TOLA_RS02015 dcf83449402fc6ce944790d7fe65c845 479 Gene3D G3DSA:3.40.1190.20 12 315 1.7E-72 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS09865 c7097bab6f61a1d29bb25df49dcf4ac7 286 PANTHER PTHR10584 1 285 3.7E-60 T 22-04-2016 TOLA_RS09865 c7097bab6f61a1d29bb25df49dcf4ac7 286 SUPERFAMILY SSF53613 1 285 2.49E-61 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS09865 c7097bab6f61a1d29bb25df49dcf4ac7 286 PRINTS PR00990 Ribokinase signature 33 52 8.4E-19 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS09865 c7097bab6f61a1d29bb25df49dcf4ac7 286 PRINTS PR00990 Ribokinase signature 172 187 8.4E-19 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS09865 c7097bab6f61a1d29bb25df49dcf4ac7 286 PRINTS PR00990 Ribokinase signature 215 226 8.4E-19 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS09865 c7097bab6f61a1d29bb25df49dcf4ac7 286 PRINTS PR00990 Ribokinase signature 105 118 8.4E-19 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS09865 c7097bab6f61a1d29bb25df49dcf4ac7 286 PRINTS PR00990 Ribokinase signature 6 27 8.4E-19 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS09865 c7097bab6f61a1d29bb25df49dcf4ac7 286 Gene3D G3DSA:3.40.1190.20 1 285 3.4E-69 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS09865 c7097bab6f61a1d29bb25df49dcf4ac7 286 PANTHER PTHR10584:SF166 1 285 3.7E-60 T 22-04-2016 TOLA_RS09865 c7097bab6f61a1d29bb25df49dcf4ac7 286 Pfam PF00294 pfkB family carbohydrate kinase 1 285 8.3E-47 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB TOLA_RS09145 cf085ad2329f72bb485a455d007d8bde 253 Pfam PF01618 MotA/TolQ/ExbB proton channel family 85 213 3.0E-35 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 TOLA_RS09145 cf085ad2329f72bb485a455d007d8bde 253 PANTHER PTHR30625 27 247 5.6E-43 T 22-04-2016 TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 SUPERFAMILY SSF46689 460 513 3.14E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 SUPERFAMILY SSF55021 2 69 2.94E-5 T 22-04-2016 TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 PANTHER PTHR32071:SF3 7 517 4.1E-159 T 22-04-2016 TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 Gene3D G3DSA:1.10.10.60 460 514 4.5E-23 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 SUPERFAMILY SSF55785 81 172 1.92E-6 T 22-04-2016 IPR000014 PAS domain TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 Gene3D G3DSA:3.30.70.260 2 68 3.9E-4 T 22-04-2016 TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 230 243 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 SUPERFAMILY SSF52540 209 447 4.39E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 419 428 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 Gene3D G3DSA:3.40.50.300 202 378 7.7E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 SMART SM00091 80 146 9.5E-4 T 22-04-2016 IPR000014 PAS domain TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 Gene3D G3DSA:3.30.450.20 77 179 2.3E-6 T 22-04-2016 TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 SMART SM00382 226 373 7.4E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 PANTHER PTHR32071 7 517 4.1E-159 T 22-04-2016 TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 Pfam PF00158 Sigma-54 interaction domain 208 372 3.2E-52 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 466 514 3.7E-26 T 22-04-2016 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 Pfam PF13188 PAS domain 82 132 2.6E-4 T 22-04-2016 IPR000014 PAS domain TOLA_RS09810 dcd64fc458bf4b7d8c7d65570645b6a3 518 Gene3D G3DSA:1.10.8.60 379 455 9.8E-22 T 22-04-2016 TOLA_RS10010 71d03b50acbb1eb906c0632bc5e1a6fd 80 Pfam PF02416 mttA/Hcf106 family 4 33 1.5E-5 T 22-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TOLA_RS10010 71d03b50acbb1eb906c0632bc5e1a6fd 80 PANTHER PTHR33162 1 64 1.8E-23 T 22-04-2016 TOLA_RS10010 71d03b50acbb1eb906c0632bc5e1a6fd 80 PANTHER PTHR33162:SF4 1 64 1.8E-23 T 22-04-2016 TOLA_RS10010 71d03b50acbb1eb906c0632bc5e1a6fd 80 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 66 1.8E-23 T 22-04-2016 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 TOLA_RS10010 71d03b50acbb1eb906c0632bc5e1a6fd 80 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 2.1E-21 T 22-04-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 TOLA_RS10010 71d03b50acbb1eb906c0632bc5e1a6fd 80 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 2.1E-21 T 22-04-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 TOLA_RS10010 71d03b50acbb1eb906c0632bc5e1a6fd 80 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 2.1E-21 T 22-04-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 TOLA_RS15710 8eb57abd647a8d3d9176517495191196 298 Gene3D G3DSA:3.60.15.10 36 297 2.8E-28 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS15710 8eb57abd647a8d3d9176517495191196 298 PANTHER PTHR15032 38 298 1.8E-35 T 22-04-2016 TOLA_RS15710 8eb57abd647a8d3d9176517495191196 298 PANTHER PTHR15032:SF13 38 298 1.8E-35 T 22-04-2016 TOLA_RS15710 8eb57abd647a8d3d9176517495191196 298 SUPERFAMILY SSF56281 38 296 7.42E-19 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS15710 8eb57abd647a8d3d9176517495191196 298 Pfam PF12706 Beta-lactamase superfamily domain 56 261 3.3E-12 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS01090 59e87f13eccb82604aa3f297ea8e6b72 183 PANTHER PTHR37625 6 152 1.4E-29 T 22-04-2016 TOLA_RS01090 59e87f13eccb82604aa3f297ea8e6b72 183 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 5 144 7.4E-37 T 22-04-2016 IPR017734 Type VI secretion system, lipoprotein SciN TOLA_RS01090 59e87f13eccb82604aa3f297ea8e6b72 183 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 13 141 1.3E-36 T 22-04-2016 IPR017734 Type VI secretion system, lipoprotein SciN TOLA_RS16365 0566f13fd299b0e1dcadbc922e191450 145 Pfam PF00293 NUDIX domain 8 80 1.1E-9 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TOLA_RS16365 0566f13fd299b0e1dcadbc922e191450 145 Gene3D G3DSA:3.90.79.10 8 122 3.9E-14 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS16365 0566f13fd299b0e1dcadbc922e191450 145 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TOLA_RS16365 0566f13fd299b0e1dcadbc922e191450 145 SUPERFAMILY SSF55811 7 128 1.49E-14 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS05765 8cb055fa821a3cf263dafd0e77c393d9 330 PANTHER PTHR10859:SF86 3 327 1.6E-143 T 22-04-2016 TOLA_RS05765 8cb055fa821a3cf263dafd0e77c393d9 330 Gene3D G3DSA:3.90.550.10 7 139 1.6E-27 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS05765 8cb055fa821a3cf263dafd0e77c393d9 330 Pfam PF00535 Glycosyl transferase family 2 9 173 5.4E-34 T 22-04-2016 IPR001173 Glycosyltransferase 2-like TOLA_RS05765 8cb055fa821a3cf263dafd0e77c393d9 330 PANTHER PTHR10859 3 327 1.6E-143 T 22-04-2016 TOLA_RS05765 8cb055fa821a3cf263dafd0e77c393d9 330 SUPERFAMILY SSF53448 6 258 2.25E-43 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS01450 172b37653045cd302c8523942967a240 335 PANTHER PTHR10366:SF77 2 335 3.8E-175 T 22-04-2016 TOLA_RS01450 172b37653045cd302c8523942967a240 335 PANTHER PTHR10366 2 335 3.8E-175 T 22-04-2016 TOLA_RS01450 172b37653045cd302c8523942967a240 335 Gene3D G3DSA:3.40.50.720 1 196 4.8E-61 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01450 172b37653045cd302c8523942967a240 335 Gene3D G3DSA:3.90.25.10 197 231 2.9E-21 T 22-04-2016 TOLA_RS01450 172b37653045cd302c8523942967a240 335 Gene3D G3DSA:3.90.25.10 296 331 2.9E-21 T 22-04-2016 TOLA_RS01450 172b37653045cd302c8523942967a240 335 PRINTS PR01713 Nucleotide sugar epimerase signature 256 271 6.6E-27 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 TOLA_RS01450 172b37653045cd302c8523942967a240 335 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 6.6E-27 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 TOLA_RS01450 172b37653045cd302c8523942967a240 335 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 6.6E-27 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 TOLA_RS01450 172b37653045cd302c8523942967a240 335 PRINTS PR01713 Nucleotide sugar epimerase signature 295 312 6.6E-27 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 TOLA_RS01450 172b37653045cd302c8523942967a240 335 SUPERFAMILY SSF51735 1 333 3.58E-91 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01450 172b37653045cd302c8523942967a240 335 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 1.3E-54 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04795 3b7c4ebf9318ea148a4bc2a11fb474c2 304 SUPERFAMILY SSF53448 9 289 3.6E-61 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS04795 3b7c4ebf9318ea148a4bc2a11fb474c2 304 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 277 4.4E-112 T 22-04-2016 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 TOLA_RS04795 3b7c4ebf9318ea148a4bc2a11fb474c2 304 Gene3D G3DSA:3.90.550.10 9 288 1.1E-70 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS04795 3b7c4ebf9318ea148a4bc2a11fb474c2 304 PANTHER PTHR22572:SF118 10 300 1.1E-137 T 22-04-2016 TOLA_RS04795 3b7c4ebf9318ea148a4bc2a11fb474c2 304 PANTHER PTHR22572 10 300 1.1E-137 T 22-04-2016 TOLA_RS04795 3b7c4ebf9318ea148a4bc2a11fb474c2 304 Pfam PF00483 Nucleotidyl transferase 11 281 1.0E-24 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 TOLA_RS04645 59d8472784778a7ceb6c3075af8027dc 494 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 144 164 4.6E-42 T 22-04-2016 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 TOLA_RS04645 59d8472784778a7ceb6c3075af8027dc 494 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 287 303 4.6E-42 T 22-04-2016 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 TOLA_RS04645 59d8472784778a7ceb6c3075af8027dc 494 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 260 279 4.6E-42 T 22-04-2016 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 TOLA_RS04645 59d8472784778a7ceb6c3075af8027dc 494 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 327 346 4.6E-42 T 22-04-2016 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 TOLA_RS04645 59d8472784778a7ceb6c3075af8027dc 494 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 397 418 4.6E-42 T 22-04-2016 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 TOLA_RS04645 59d8472784778a7ceb6c3075af8027dc 494 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 240 259 4.6E-42 T 22-04-2016 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 TOLA_RS04645 59d8472784778a7ceb6c3075af8027dc 494 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 11 491 8.6E-87 T 22-04-2016 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 TOLA_RS04645 59d8472784778a7ceb6c3075af8027dc 494 SUPERFAMILY SSF55486 3 491 9.4E-118 T 22-04-2016 TOLA_RS04645 59d8472784778a7ceb6c3075af8027dc 494 PANTHER PTHR34217:SF1 1 494 2.1E-231 T 22-04-2016 TOLA_RS04645 59d8472784778a7ceb6c3075af8027dc 494 PANTHER PTHR34217 1 494 2.1E-231 T 22-04-2016 TOLA_RS04645 59d8472784778a7ceb6c3075af8027dc 494 PIRSF PIRSF006615 1 494 2.8E-189 T 22-04-2016 IPR001333 Peptidase M32, carboxypeptidase Taq metallopeptidase GO:0004181|GO:0006508 TOLA_RS00030 b6929cd7d0b3467ece9fa4d545d09c68 808 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 361 460 1.9E-11 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS00030 b6929cd7d0b3467ece9fa4d545d09c68 808 Pfam PF00563 EAL domain 559 791 6.6E-68 T 22-04-2016 IPR001633 EAL domain TOLA_RS00030 b6929cd7d0b3467ece9fa4d545d09c68 808 Gene3D G3DSA:3.30.70.270 367 550 2.4E-23 T 22-04-2016 TOLA_RS00030 b6929cd7d0b3467ece9fa4d545d09c68 808 PANTHER PTHR33121 551 801 9.7E-69 T 22-04-2016 TOLA_RS00030 b6929cd7d0b3467ece9fa4d545d09c68 808 SUPERFAMILY SSF141868 558 803 2.09E-78 T 22-04-2016 IPR001633 EAL domain TOLA_RS00030 b6929cd7d0b3467ece9fa4d545d09c68 808 SMART SM00267 354 543 1.2E-9 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS00030 b6929cd7d0b3467ece9fa4d545d09c68 808 Pfam PF00990 Diguanylate cyclase, GGDEF domain 365 528 3.4E-16 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS00030 b6929cd7d0b3467ece9fa4d545d09c68 808 Gene3D G3DSA:3.20.20.450 557 801 1.5E-83 T 22-04-2016 IPR001633 EAL domain TOLA_RS00030 b6929cd7d0b3467ece9fa4d545d09c68 808 PANTHER PTHR33121:SF13 551 801 9.7E-69 T 22-04-2016 TOLA_RS00030 b6929cd7d0b3467ece9fa4d545d09c68 808 SUPERFAMILY SSF55073 370 544 1.65E-21 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS00030 b6929cd7d0b3467ece9fa4d545d09c68 808 SMART SM00052 553 796 3.1E-93 T 22-04-2016 IPR001633 EAL domain TOLA_RS15260 9b230d8b0cfd875b122c9660b3de6316 326 Pfam PF01636 Phosphotransferase enzyme family 31 262 3.8E-33 T 22-04-2016 IPR002575 Aminoglycoside phosphotransferase TOLA_RS15260 9b230d8b0cfd875b122c9660b3de6316 326 Hamap MF_01497 Stress response kinase A [srkA]. 3 316 42.082 T 22-04-2016 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 TOLA_RS15260 9b230d8b0cfd875b122c9660b3de6316 326 SUPERFAMILY SSF56112 4 318 3.86E-79 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS15260 9b230d8b0cfd875b122c9660b3de6316 326 PANTHER PTHR39573 1 326 2.3E-126 T 22-04-2016 TOLA_RS15260 9b230d8b0cfd875b122c9660b3de6316 326 Gene3D G3DSA:3.90.1200.10 114 320 1.3E-43 T 22-04-2016 TOLA_RS15260 9b230d8b0cfd875b122c9660b3de6316 326 Gene3D G3DSA:3.30.200.20 36 91 6.3E-5 T 22-04-2016 TOLA_RS15260 9b230d8b0cfd875b122c9660b3de6316 326 PANTHER PTHR39573:SF1 1 326 2.3E-126 T 22-04-2016 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 TOLA_RS13050 3d06728201f828919ff61d9265b0bd89 423 PANTHER PTHR10632:SF7 1 421 6.8E-152 T 22-04-2016 TOLA_RS13050 3d06728201f828919ff61d9265b0bd89 423 SUPERFAMILY SSF51905 157 303 4.86E-6 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS13050 3d06728201f828919ff61d9265b0bd89 423 PANTHER PTHR10632 1 421 6.8E-152 T 22-04-2016 TOLA_RS13050 3d06728201f828919ff61d9265b0bd89 423 Gene3D G3DSA:3.50.50.60 264 341 4.7E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS13050 3d06728201f828919ff61d9265b0bd89 423 Gene3D G3DSA:3.50.50.60 3 117 4.7E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS13050 3d06728201f828919ff61d9265b0bd89 423 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 307 1.2E-15 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS13050 3d06728201f828919ff61d9265b0bd89 423 SUPERFAMILY SSF51905 4 109 5.02E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS13050 3d06728201f828919ff61d9265b0bd89 423 SUPERFAMILY SSF51905 257 339 5.02E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS00225 aa820317bd93f630977a53157c1b4660 296 PANTHER PTHR32243 3 296 4.8E-138 T 22-04-2016 TOLA_RS00225 aa820317bd93f630977a53157c1b4660 296 Gene3D G3DSA:1.10.3720.10 9 283 2.6E-63 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00225 aa820317bd93f630977a53157c1b4660 296 PANTHER PTHR32243:SF4 3 296 4.8E-138 T 22-04-2016 TOLA_RS00225 aa820317bd93f630977a53157c1b4660 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 286 2.4E-16 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00225 aa820317bd93f630977a53157c1b4660 296 SUPERFAMILY SSF161098 10 296 3.46E-67 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS14935 f4fd8a441cc488ea3b82af7c162e00ab 967 SUPERFAMILY SSF81593 828 955 2.2E-27 T 22-04-2016 TOLA_RS14935 f4fd8a441cc488ea3b82af7c162e00ab 967 SUPERFAMILY SSF81301 536 826 1.77E-85 T 22-04-2016 TOLA_RS14935 f4fd8a441cc488ea3b82af7c162e00ab 967 SUPERFAMILY SSF81301 40 299 3.92E-82 T 22-04-2016 TOLA_RS14935 f4fd8a441cc488ea3b82af7c162e00ab 967 SUPERFAMILY SSF81593 300 449 2.12E-41 T 22-04-2016 TOLA_RS14935 f4fd8a441cc488ea3b82af7c162e00ab 967 Gene3D G3DSA:3.30.460.10 650 822 4.1E-57 T 22-04-2016 TOLA_RS14935 f4fd8a441cc488ea3b82af7c162e00ab 967 Gene3D G3DSA:3.30.460.10 125 298 4.6E-61 T 22-04-2016 TOLA_RS14935 f4fd8a441cc488ea3b82af7c162e00ab 967 Pfam PF08335 GlnD PII-uridylyltransferase 838 925 1.2E-9 T 22-04-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 TOLA_RS14935 f4fd8a441cc488ea3b82af7c162e00ab 967 Pfam PF08335 GlnD PII-uridylyltransferase 310 449 2.0E-40 T 22-04-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 TOLA_RS14935 f4fd8a441cc488ea3b82af7c162e00ab 967 PANTHER PTHR30621 5 951 0.0 T 22-04-2016 TOLA_RS14935 f4fd8a441cc488ea3b82af7c162e00ab 967 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 38 957 18.942 T 22-04-2016 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 TOLA_RS14935 f4fd8a441cc488ea3b82af7c162e00ab 967 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 563 816 3.3E-87 T 22-04-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 TOLA_RS14935 f4fd8a441cc488ea3b82af7c162e00ab 967 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 43 282 2.3E-90 T 22-04-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 TOLA_RS09185 e25c6fa32b7f6379a754562bc82f1648 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TOLA_RS09185 e25c6fa32b7f6379a754562bc82f1648 236 Pfam PF00106 short chain dehydrogenase 2 187 3.7E-23 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09185 e25c6fa32b7f6379a754562bc82f1648 236 SUPERFAMILY SSF51735 2 226 1.77E-32 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09185 e25c6fa32b7f6379a754562bc82f1648 236 Gene3D G3DSA:3.40.50.720 2 233 1.9E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09185 e25c6fa32b7f6379a754562bc82f1648 236 PANTHER PTHR24322 6 125 7.6E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09185 e25c6fa32b7f6379a754562bc82f1648 236 PANTHER PTHR24322 142 175 7.6E-13 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09185 e25c6fa32b7f6379a754562bc82f1648 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.4E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09185 e25c6fa32b7f6379a754562bc82f1648 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 4.4E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS09185 e25c6fa32b7f6379a754562bc82f1648 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 4.4E-12 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS15495 cfaa698e923d364141ef4c04382103ea 241 Pfam PF00072 Response regulator receiver domain 9 118 5.4E-30 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS15495 cfaa698e923d364141ef4c04382103ea 241 SUPERFAMILY SSF46894 135 234 1.53E-26 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TOLA_RS15495 cfaa698e923d364141ef4c04382103ea 241 PANTHER PTHR26402 7 237 5.7E-98 T 22-04-2016 TOLA_RS15495 cfaa698e923d364141ef4c04382103ea 241 SUPERFAMILY SSF52172 7 132 3.7E-43 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS15495 cfaa698e923d364141ef4c04382103ea 241 Gene3D G3DSA:1.10.10.10 135 236 2.7E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15495 cfaa698e923d364141ef4c04382103ea 241 Gene3D G3DSA:3.40.50.2300 7 130 6.6E-43 T 22-04-2016 TOLA_RS15495 cfaa698e923d364141ef4c04382103ea 241 PANTHER PTHR26402:SF292 7 237 5.7E-98 T 22-04-2016 TOLA_RS15495 cfaa698e923d364141ef4c04382103ea 241 SMART SM00862 157 233 1.7E-25 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS15495 cfaa698e923d364141ef4c04382103ea 241 SMART SM00448 7 117 4.1E-46 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS15495 cfaa698e923d364141ef4c04382103ea 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 159 233 7.5E-24 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS07885 649ceacfdc5a4eb49e08b6cc92df87d8 183 Pfam PF01066 CDP-alcohol phosphatidyltransferase 3 70 4.9E-20 T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TOLA_RS07885 649ceacfdc5a4eb49e08b6cc92df87d8 183 PIRSF PIRSF000847 1 183 3.3E-45 T 22-04-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 TOLA_RS07885 649ceacfdc5a4eb49e08b6cc92df87d8 183 PANTHER PTHR14269:SF13 1 178 8.1E-85 T 22-04-2016 TOLA_RS07885 649ceacfdc5a4eb49e08b6cc92df87d8 183 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 48 70 - T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TOLA_RS07885 649ceacfdc5a4eb49e08b6cc92df87d8 183 PANTHER PTHR14269 1 178 8.1E-85 T 22-04-2016 TOLA_RS07885 649ceacfdc5a4eb49e08b6cc92df87d8 183 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 3 177 1.2E-56 T 22-04-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 TOLA_RS02415 0f473c9b46bde5aa28c97941c0db1c2d 221 PANTHER PTHR30353:SF0 1 221 5.1E-86 T 22-04-2016 TOLA_RS02415 0f473c9b46bde5aa28c97941c0db1c2d 221 Pfam PF09335 SNARE associated Golgi protein 49 178 7.9E-24 T 22-04-2016 IPR032816 SNARE associated Golgi protein TOLA_RS02415 0f473c9b46bde5aa28c97941c0db1c2d 221 PANTHER PTHR30353 1 221 5.1E-86 T 22-04-2016 IPR032818 DedA family TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 PIRSF PIRSF000478 1 438 4.9E-152 T 22-04-2016 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 67 1.6E-20 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 113 128 - T 22-04-2016 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 SUPERFAMILY SSF54680 337 438 1.16E-29 T 22-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 Gene3D G3DSA:1.20.970.10 2 67 3.7E-29 T 22-04-2016 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 Gene3D G3DSA:3.90.1170.30 339 430 4.8E-31 T 22-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 Pfam PF00591 Glycosyl transferase family, a/b domain 80 309 5.5E-47 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 SUPERFAMILY SSF52418 74 332 4.32E-88 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 Hamap MF_01628 Thymidine phosphorylase [deoA]. 1 439 53.574 T 22-04-2016 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|UniPathway: UPA00578 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 PANTHER PTHR10515:SF0 5 442 3.9E-209 T 22-04-2016 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 SUPERFAMILY SSF47648 2 70 4.06E-21 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 PANTHER PTHR10515 5 442 3.9E-209 T 22-04-2016 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 351 423 1.3E-21 T 22-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 5 423 3.1E-163 T 22-04-2016 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|UniPathway: UPA00578 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 TIGRFAM TIGR02643 T_phosphoryl: thymidine phosphorylase 2 438 1.5E-222 T 22-04-2016 IPR013465 Thymidine phosphorylase GO:0006213|GO:0009032 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|UniPathway: UPA00578 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 SMART SM00941 350 424 1.5E-26 T 22-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 TOLA_RS13215 59103e9e63c4c6a21737c601cc15a540 443 Gene3D G3DSA:3.40.1030.10 76 338 5.8E-109 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 TOLA_RS01375 4beee0f7b34c23d94682e0cd54ad5195 481 SUPERFAMILY SSF111283 18 480 6.67E-136 T 22-04-2016 TOLA_RS01375 4beee0f7b34c23d94682e0cd54ad5195 481 PIRSF PIRSF004919 14 481 6.0E-143 T 22-04-2016 IPR025502 TldD KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS01375 4beee0f7b34c23d94682e0cd54ad5195 481 Pfam PF01523 Putative modulator of DNA gyrase 37 332 1.3E-66 T 22-04-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS01375 4beee0f7b34c23d94682e0cd54ad5195 481 PANTHER PTHR30624:SF4 6 481 6.1E-247 T 22-04-2016 TOLA_RS01375 4beee0f7b34c23d94682e0cd54ad5195 481 PANTHER PTHR30624 6 481 6.1E-247 T 22-04-2016 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 PIRSF PIRSF000159 1 1185 0.0 T 22-04-2016 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 Pfam PF10371 Domain of unknown function 634 684 7.8E-20 T 22-04-2016 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 SUPERFAMILY SSF52518 5 259 1.91E-74 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 SUPERFAMILY SSF52518 799 1181 1.71E-126 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 Gene3D G3DSA:4.10.780.10 636 674 9.8E-13 T 22-04-2016 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 Gene3D G3DSA:3.40.920.10 424 625 9.0E-73 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 PANTHER PTHR32154 4 1186 0.0 T 22-04-2016 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 Gene3D G3DSA:3.40.50.970 5 259 4.0E-107 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 6 1177 0.0 T 22-04-2016 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 18 249 2.4E-78 T 22-04-2016 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 Gene3D G3DSA:3.40.50.970 801 1177 1.3E-132 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 432 612 1.7E-23 T 22-04-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 SUPERFAMILY SSF53323 424 674 7.06E-73 T 22-04-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 751 762 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 695 706 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 Gene3D G3DSA:3.40.50.920 260 421 5.7E-57 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 Pfam PF12838 4Fe-4S dicluster domain 695 765 3.0E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 966 1078 3.8E-11 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 SUPERFAMILY SSF54862 671 844 2.65E-21 T 22-04-2016 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 SMART SM00890 632 685 3.1E-20 T 22-04-2016 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 PANTHER PTHR32154:SF0 4 1186 0.0 T 22-04-2016 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 270 356 1.8E-13 T 22-04-2016 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 Gene3D G3DSA:3.30.70.20 678 777 2.8E-20 T 22-04-2016 TOLA_RS10150 c7cb958ae2fc324348d033860effd516 1190 SUPERFAMILY SSF52922 260 421 5.28E-40 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS11525 3db5839102c238d7c2cff720de57f6c4 382 Pfam PF13289 SIR2-like domain 128 359 3.7E-13 T 22-04-2016 TOLA_RS11525 3db5839102c238d7c2cff720de57f6c4 382 SUPERFAMILY SSF52467 266 348 9.37E-6 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain TOLA_RS11525 3db5839102c238d7c2cff720de57f6c4 382 SUPERFAMILY SSF52467 188 211 9.37E-6 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain TOLA_RS11525 3db5839102c238d7c2cff720de57f6c4 382 SUPERFAMILY SSF52467 123 141 9.37E-6 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain TOLA_RS06965 bf639485b0d743ba5534b087e854fe35 361 Gene3D G3DSA:3.90.1150.10 259 360 5.9E-43 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS06965 bf639485b0d743ba5534b087e854fe35 361 PANTHER PTHR21152 1 361 7.0E-182 T 22-04-2016 TOLA_RS06965 bf639485b0d743ba5534b087e854fe35 361 Gene3D G3DSA:3.40.640.10 17 257 6.0E-100 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS06965 bf639485b0d743ba5534b087e854fe35 361 PANTHER PTHR21152:SF1 1 361 7.0E-182 T 22-04-2016 TOLA_RS06965 bf639485b0d743ba5534b087e854fe35 361 PIRSF PIRSF000525 1 361 5.2E-147 T 22-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 TOLA_RS06965 bf639485b0d743ba5534b087e854fe35 361 Pfam PF00266 Aminotransferase class-V 4 349 1.8E-58 T 22-04-2016 IPR000192 Aminotransferase class V domain TOLA_RS06965 bf639485b0d743ba5534b087e854fe35 361 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 360 9.0E-155 T 22-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 TOLA_RS06965 bf639485b0d743ba5534b087e854fe35 361 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 360 51.073 T 22-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 TOLA_RS06965 bf639485b0d743ba5534b087e854fe35 361 SUPERFAMILY SSF53383 1 359 2.19E-114 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS02440 2948474ce077026a500b2271fcf12dfe 180 PIRSF PIRSF039093 1 175 2.5E-85 T 22-04-2016 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 TOLA_RS02440 2948474ce077026a500b2271fcf12dfe 180 SUPERFAMILY SSF56235 2 172 2.44E-58 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS02440 2948474ce077026a500b2271fcf12dfe 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 2 171 7.7E-84 T 22-04-2016 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 TOLA_RS02440 2948474ce077026a500b2271fcf12dfe 180 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 1 172 40.548 T 22-04-2016 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 TOLA_RS02440 2948474ce077026a500b2271fcf12dfe 180 Pfam PF00227 Proteasome subunit 2 171 2.7E-24 T 22-04-2016 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: REACT_11045|Reactome: REACT_13|Reactome: REACT_13635|Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_383|Reactome: REACT_578|Reactome: REACT_6185|Reactome: REACT_6850 TOLA_RS02440 2948474ce077026a500b2271fcf12dfe 180 PANTHER PTHR32194 2 174 3.5E-120 T 22-04-2016 TOLA_RS02440 2948474ce077026a500b2271fcf12dfe 180 Gene3D G3DSA:3.60.20.10 2 173 2.1E-82 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS00760 dd314938e4e3c5673c13ac7e0a3b57d9 154 Pfam PF00588 SpoU rRNA Methylase family 2 142 1.4E-31 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TOLA_RS00760 dd314938e4e3c5673c13ac7e0a3b57d9 154 PIRSF PIRSF029256 1 154 1.8E-64 T 22-04-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 TOLA_RS00760 dd314938e4e3c5673c13ac7e0a3b57d9 154 PANTHER PTHR12029 1 153 9.7E-71 T 22-04-2016 TOLA_RS00760 dd314938e4e3c5673c13ac7e0a3b57d9 154 Gene3D G3DSA:3.40.1280.10 1 153 8.6E-63 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TOLA_RS00760 dd314938e4e3c5673c13ac7e0a3b57d9 154 PANTHER PTHR12029:SF31 1 153 9.7E-71 T 22-04-2016 TOLA_RS00760 dd314938e4e3c5673c13ac7e0a3b57d9 154 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 153 1.2E-60 T 22-04-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 TOLA_RS00760 dd314938e4e3c5673c13ac7e0a3b57d9 154 SUPERFAMILY SSF75217 1 152 1.77E-42 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases TOLA_RS00760 dd314938e4e3c5673c13ac7e0a3b57d9 154 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 32.187 T 22-04-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 TOLA_RS00725 f129720f696be6fdf01dac9c112c06ce 254 Gene3D G3DSA:3.40.50.300 2 250 1.4E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00725 f129720f696be6fdf01dac9c112c06ce 254 Pfam PF00005 ABC transporter 21 180 7.4E-35 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS00725 f129720f696be6fdf01dac9c112c06ce 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 232 252 2.5E-10 T 22-04-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TOLA_RS00725 f129720f696be6fdf01dac9c112c06ce 254 SMART SM00382 29 230 1.6E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS00725 f129720f696be6fdf01dac9c112c06ce 254 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS00725 f129720f696be6fdf01dac9c112c06ce 254 PANTHER PTHR24220 120 254 3.9E-128 T 22-04-2016 TOLA_RS00725 f129720f696be6fdf01dac9c112c06ce 254 PANTHER PTHR24220 6 104 3.9E-128 T 22-04-2016 TOLA_RS00725 f129720f696be6fdf01dac9c112c06ce 254 PANTHER PTHR24220:SF358 120 254 3.9E-128 T 22-04-2016 TOLA_RS00725 f129720f696be6fdf01dac9c112c06ce 254 PANTHER PTHR24220:SF358 6 104 3.9E-128 T 22-04-2016 TOLA_RS00725 f129720f696be6fdf01dac9c112c06ce 254 SUPERFAMILY SSF52540 4 252 3.3E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS16180 b46c402976572c4f8cd15d273f0a2b99 349 PANTHER PTHR22893:SF14 1 349 1.7E-166 T 22-04-2016 TOLA_RS16180 b46c402976572c4f8cd15d273f0a2b99 349 Gene3D G3DSA:3.20.20.70 1 349 9.4E-125 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS16180 b46c402976572c4f8cd15d273f0a2b99 349 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 326 8.5E-82 T 22-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 TOLA_RS16180 b46c402976572c4f8cd15d273f0a2b99 349 SUPERFAMILY SSF51395 1 348 1.42E-116 T 22-04-2016 TOLA_RS16180 b46c402976572c4f8cd15d273f0a2b99 349 PANTHER PTHR22893 1 349 1.7E-166 T 22-04-2016 TOLA_RS01700 0569dcb8ad433c297056d1f1413c9044 273 SUPERFAMILY SSF56784 3 272 7.05E-63 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS01700 0569dcb8ad433c297056d1f1413c9044 273 ProSitePatterns PS01229 Hypothetical cof family signature 2. 222 244 - T 22-04-2016 TOLA_RS01700 0569dcb8ad433c297056d1f1413c9044 273 PANTHER PTHR10000 1 273 6.5E-63 T 22-04-2016 TOLA_RS01700 0569dcb8ad433c297056d1f1413c9044 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 74 9.0E-12 T 22-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 TOLA_RS01700 0569dcb8ad433c297056d1f1413c9044 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 268 3.6E-60 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS01700 0569dcb8ad433c297056d1f1413c9044 273 PANTHER PTHR10000:SF8 1 273 6.5E-63 T 22-04-2016 TOLA_RS01700 0569dcb8ad433c297056d1f1413c9044 273 Gene3D G3DSA:3.40.50.1000 1 74 1.2E-54 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS01700 0569dcb8ad433c297056d1f1413c9044 273 Gene3D G3DSA:3.40.50.1000 177 273 1.2E-54 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS01700 0569dcb8ad433c297056d1f1413c9044 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 268 3.2E-55 T 22-04-2016 IPR000150 Cof protein GO:0016787 TOLA_RS01700 0569dcb8ad433c297056d1f1413c9044 273 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 22-04-2016 IPR000150 Cof protein GO:0016787 TOLA_RS11845 9025acbd04f6a8d6d708766e06c53e5a 192 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 2 191 24.246 T 22-04-2016 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 TOLA_RS11845 9025acbd04f6a8d6d708766e06c53e5a 192 Pfam PF02508 Rnf-Nqr subunit, membrane protein 6 190 8.2E-56 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 TOLA_RS11845 9025acbd04f6a8d6d708766e06c53e5a 192 PANTHER PTHR30335:SF0 2 191 4.7E-98 T 22-04-2016 TOLA_RS11845 9025acbd04f6a8d6d708766e06c53e5a 192 PANTHER PTHR30335 2 191 4.7E-98 T 22-04-2016 TOLA_RS11845 9025acbd04f6a8d6d708766e06c53e5a 192 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 190 1.3E-76 T 22-04-2016 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 TOLA_RS11845 9025acbd04f6a8d6d708766e06c53e5a 192 PIRSF PIRSF006102 1 192 1.1E-53 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 SUPERFAMILY SSF52540 42 352 7.53E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 6.3E-179 T 22-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 Pfam PF00448 SRP54-type protein, GTPase domain 101 296 1.5E-74 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 Gene3D G3DSA:1.10.260.30 329 431 2.9E-39 T 22-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 440 34.166 T 22-04-2016 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 PANTHER PTHR11564:SF7 1 436 9.5E-264 T 22-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 SMART SM00963 1 86 1.7E-37 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 SMART SM00382 99 247 2.4E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 Gene3D G3DSA:1.20.120.140 2 88 1.8E-35 T 22-04-2016 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.0E-22 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 Gene3D G3DSA:3.40.50.300 94 297 1.6E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 Pfam PF02978 Signal peptide binding domain 329 427 8.1E-32 T 22-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 SUPERFAMILY SSF47446 298 430 7.63E-45 T 22-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 PANTHER PTHR11564 1 436 9.5E-264 T 22-04-2016 TOLA_RS14320 810439e21b8c20a62a233cd1e908d580 457 SMART SM00962 100 296 5.3E-116 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 TOLA_RS10420 f221257f3f6d513d646770021ccf87b6 465 Gene3D G3DSA:3.90.550.10 2 269 1.1E-101 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS10420 f221257f3f6d513d646770021ccf87b6 465 PANTHER PTHR12526:SF387 152 287 7.3E-110 T 22-04-2016 TOLA_RS10420 f221257f3f6d513d646770021ccf87b6 465 PANTHER PTHR12526:SF387 350 462 7.3E-110 T 22-04-2016 TOLA_RS10420 f221257f3f6d513d646770021ccf87b6 465 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 2 462 6.2E-234 T 22-04-2016 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS10420 f221257f3f6d513d646770021ccf87b6 465 SUPERFAMILY SSF53448 2 280 1.78E-74 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS10420 f221257f3f6d513d646770021ccf87b6 465 SUPERFAMILY SSF51182 183 461 1.84E-86 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS10420 f221257f3f6d513d646770021ccf87b6 465 Pfam PF00483 Nucleotidyl transferase 4 285 7.0E-76 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 TOLA_RS10420 f221257f3f6d513d646770021ccf87b6 465 PANTHER PTHR12526 152 287 7.3E-110 T 22-04-2016 TOLA_RS10420 f221257f3f6d513d646770021ccf87b6 465 PANTHER PTHR12526 350 462 7.3E-110 T 22-04-2016 TOLA_RS10420 f221257f3f6d513d646770021ccf87b6 465 Gene3D G3DSA:2.60.120.10 356 461 2.4E-40 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS10420 f221257f3f6d513d646770021ccf87b6 465 Pfam PF01050 Mannose-6-phosphate isomerase 313 462 4.3E-66 T 22-04-2016 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS02610 2db1884c514248615e91680c6c595e51 553 PANTHER PTHR30109 1 551 8.7E-288 T 22-04-2016 TOLA_RS02610 2db1884c514248615e91680c6c595e51 553 Gene3D G3DSA:1.20.1270.20 162 235 2.2E-25 T 22-04-2016 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TOLA_RS02610 2db1884c514248615e91680c6c595e51 553 PIRSF PIRSF000076 1 553 6.9E-239 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 TOLA_RS02610 2db1884c514248615e91680c6c595e51 553 Gene3D G3DSA:3.40.50.2030 237 382 1.8E-65 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TOLA_RS02610 2db1884c514248615e91680c6c595e51 553 Pfam PF03063 Prismane/CO dehydrogenase family 1 548 2.7E-167 T 22-04-2016 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 TOLA_RS02610 2db1884c514248615e91680c6c595e51 553 PANTHER PTHR30109:SF0 1 551 8.7E-288 T 22-04-2016 TOLA_RS02610 2db1884c514248615e91680c6c595e51 553 SUPERFAMILY SSF56821 1 551 1.14E-196 T 22-04-2016 IPR011254 Prismane-like GO:0003824|GO:0016491|GO:0055114 TOLA_RS02610 2db1884c514248615e91680c6c595e51 553 Gene3D G3DSA:3.40.50.2030 383 550 5.2E-71 T 22-04-2016 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TOLA_RS02610 2db1884c514248615e91680c6c595e51 553 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 1 551 1.5E-228 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 TOLA_RS02610 2db1884c514248615e91680c6c595e51 553 Hamap MF_00069 Hydroxylamine reductase [hcp]. 1 552 20.755 T 22-04-2016 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 TOLA_RS02610 2db1884c514248615e91680c6c595e51 553 Gene3D G3DSA:1.20.1270.20 1 109 3.8E-38 T 22-04-2016 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TOLA_RS02610 2db1884c514248615e91680c6c595e51 553 Gene3D G3DSA:1.20.1270.20 141 161 3.8E-38 T 22-04-2016 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 SUPERFAMILY SSF47794 432 495 2.04E-15 T 22-04-2016 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 Gene3D G3DSA:1.10.150.20 360 423 8.0E-20 T 22-04-2016 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 Gene3D G3DSA:1.10.150.20 432 498 3.4E-22 T 22-04-2016 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 SUPERFAMILY SSF54814 203 281 7.19E-30 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 446 492 8.8E-15 T 22-04-2016 IPR010214 Transcription termination factor NusA, C-terminal duplication TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 368 417 5.3E-19 T 22-04-2016 IPR010214 Transcription termination factor NusA, C-terminal duplication TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 SUPERFAMILY SSF50249 135 202 4.83E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 Pfam PF14520 Helix-hairpin-helix domain 435 489 3.2E-8 T 22-04-2016 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 SMART SM00316 136 203 1.8E-7 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 PANTHER PTHR22648:SF0 1 451 4.9E-182 T 22-04-2016 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 Gene3D G3DSA:2.40.50.140 131 201 2.8E-22 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 345 1.2E-126 T 22-04-2016 IPR010213 Transcription termination factor NusA GO:0003723 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 Gene3D G3DSA:3.30.1480.10 1 127 2.6E-45 T 22-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 413 28.958 T 22-04-2016 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 Gene3D G3DSA:3.30.300.20 281 349 4.9E-26 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 Pfam PF08529 NusA N-terminal domain 4 126 4.0E-38 T 22-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 SUPERFAMILY SSF47794 359 419 3.77E-15 T 22-04-2016 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 Gene3D G3DSA:3.30.300.20 202 280 1.1E-34 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 Pfam PF13184 NusA-like KH domain 233 298 2.0E-26 T 22-04-2016 IPR025249 KH domain, NusA-like GO:0003723 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 SUPERFAMILY SSF69705 1 129 5.89E-41 T 22-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 SUPERFAMILY SSF54814 282 346 5.49E-14 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 TOLA_RS11405 a9d04431b6c1371451b8dd4e0d37da87 499 PANTHER PTHR22648 1 451 4.9E-182 T 22-04-2016 TOLA_RS10295 0c005b7bcef61818c2d9cb4c490c96aa 292 Gene3D G3DSA:1.25.40.10 34 259 7.3E-27 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS10295 0c005b7bcef61818c2d9cb4c490c96aa 292 Pfam PF13181 Tetratricopeptide repeat 91 122 0.0055 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS10295 0c005b7bcef61818c2d9cb4c490c96aa 292 SMART SM00028 91 124 6.4E-5 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS10295 0c005b7bcef61818c2d9cb4c490c96aa 292 SMART SM00028 229 262 42.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS10295 0c005b7bcef61818c2d9cb4c490c96aa 292 SMART SM00028 57 90 1.6 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS10295 0c005b7bcef61818c2d9cb4c490c96aa 292 SMART SM00028 125 158 460.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS10295 0c005b7bcef61818c2d9cb4c490c96aa 292 SUPERFAMILY SSF48452 23 277 8.22E-67 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS10295 0c005b7bcef61818c2d9cb4c490c96aa 292 PIRSF PIRSF004654 1 286 8.0E-106 T 22-04-2016 IPR023605 Lipoprotein NlpI TOLA_RS10295 0c005b7bcef61818c2d9cb4c490c96aa 292 PANTHER PTHR23083 34 270 1.6E-19 T 22-04-2016 TOLA_RS09980 6565b572652ba98538c50d3cb6ad3b4c 429 SUPERFAMILY SSF53850 45 131 3.52E-50 T 22-04-2016 TOLA_RS09980 6565b572652ba98538c50d3cb6ad3b4c 429 SUPERFAMILY SSF53850 170 427 3.52E-50 T 22-04-2016 TOLA_RS09980 6565b572652ba98538c50d3cb6ad3b4c 429 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 9 32 8.2E-5 T 22-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TOLA_RS09980 6565b572652ba98538c50d3cb6ad3b4c 429 Gene3D G3DSA:3.40.190.10 188 323 1.3E-15 T 22-04-2016 TOLA_RS09980 6565b572652ba98538c50d3cb6ad3b4c 429 Pfam PF13416 Bacterial extracellular solute-binding protein 61 354 6.9E-20 T 22-04-2016 TOLA_RS09980 6565b572652ba98538c50d3cb6ad3b4c 429 PANTHER PTHR30222:SF8 3 130 4.3E-172 T 22-04-2016 TOLA_RS09980 6565b572652ba98538c50d3cb6ad3b4c 429 PANTHER PTHR30222:SF8 152 428 4.3E-172 T 22-04-2016 TOLA_RS09980 6565b572652ba98538c50d3cb6ad3b4c 429 PANTHER PTHR30222 3 130 4.3E-172 T 22-04-2016 TOLA_RS09980 6565b572652ba98538c50d3cb6ad3b4c 429 PANTHER PTHR30222 152 428 4.3E-172 T 22-04-2016 TOLA_RS09980 6565b572652ba98538c50d3cb6ad3b4c 429 Gene3D G3DSA:3.40.190.10 324 369 5.3E-31 T 22-04-2016 TOLA_RS09980 6565b572652ba98538c50d3cb6ad3b4c 429 Gene3D G3DSA:3.40.190.10 43 145 5.3E-31 T 22-04-2016 TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 SUPERFAMILY SSF51120 1256 1436 1.26E-26 T 22-04-2016 IPR011049 Serralysin-like metalloprotease, C-terminal TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1239 1257 - T 22-04-2016 IPR018511 Hemolysin-type calcium-binding conserved site TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1344 1362 - T 22-04-2016 IPR018511 Hemolysin-type calcium-binding conserved site TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1230 1248 - T 22-04-2016 IPR018511 Hemolysin-type calcium-binding conserved site TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1257 1275 - T 22-04-2016 IPR018511 Hemolysin-type calcium-binding conserved site TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 PRINTS PR00313 NodO calcium binding signature 1222 1233 8.4E-9 T 22-04-2016 TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 PRINTS PR00313 NodO calcium binding signature 1348 1356 8.4E-9 T 22-04-2016 TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 PRINTS PR00313 NodO calcium binding signature 1357 1366 8.4E-9 T 22-04-2016 TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 PRINTS PR00313 NodO calcium binding signature 1243 1251 8.4E-9 T 22-04-2016 TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 Gene3D G3DSA:2.150.10.10 1207 1303 8.9E-23 T 22-04-2016 IPR011049 Serralysin-like metalloprotease, C-terminal TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 Gene3D G3DSA:2.150.10.10 1305 1444 6.1E-17 T 22-04-2016 IPR011049 Serralysin-like metalloprotease, C-terminal TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 Gene3D G3DSA:2.150.10.10 1010 1020 8.9E-23 T 22-04-2016 IPR011049 Serralysin-like metalloprotease, C-terminal TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 SUPERFAMILY SSF51120 1205 1274 4.71E-13 T 22-04-2016 IPR011049 Serralysin-like metalloprotease, C-terminal TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 SUPERFAMILY SSF51120 1094 1121 4.71E-13 T 22-04-2016 IPR011049 Serralysin-like metalloprotease, C-terminal TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 1380 1446 3.5E-11 T 22-04-2016 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1215 1232 0.026 T 22-04-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1251 1268 0.75 T 22-04-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1270 1285 1.5 T 22-04-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1347 1364 0.079 T 22-04-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TOLA_RS06460 4bf119ac882de7fd13784b06470040aa 1461 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1234 1250 9.2E-4 T 22-04-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 TOLA_RS06840 2fd8acd712cad1f9ff39d3e4dc092f2e 262 PANTHER PTHR26402 1 133 5.4E-23 T 22-04-2016 TOLA_RS06840 2fd8acd712cad1f9ff39d3e4dc092f2e 262 SUPERFAMILY SSF46894 197 261 1.16E-16 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TOLA_RS06840 2fd8acd712cad1f9ff39d3e4dc092f2e 262 SMART SM00421 202 259 2.7E-15 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS06840 2fd8acd712cad1f9ff39d3e4dc092f2e 262 PANTHER PTHR26402 175 261 5.4E-23 T 22-04-2016 TOLA_RS06840 2fd8acd712cad1f9ff39d3e4dc092f2e 262 Gene3D G3DSA:1.10.10.10 204 261 6.0E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06840 2fd8acd712cad1f9ff39d3e4dc092f2e 262 ProSitePatterns PS00622 LuxR-type HTH domain signature. 219 246 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS06840 2fd8acd712cad1f9ff39d3e4dc092f2e 262 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 235 247 4.6E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS06840 2fd8acd712cad1f9ff39d3e4dc092f2e 262 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 219 235 4.6E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS06840 2fd8acd712cad1f9ff39d3e4dc092f2e 262 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 205 219 4.6E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS06840 2fd8acd712cad1f9ff39d3e4dc092f2e 262 Pfam PF00196 Bacterial regulatory proteins, luxR family 204 257 5.3E-15 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS06840 2fd8acd712cad1f9ff39d3e4dc092f2e 262 PANTHER PTHR26402:SF572 175 261 5.4E-23 T 22-04-2016 TOLA_RS06840 2fd8acd712cad1f9ff39d3e4dc092f2e 262 PANTHER PTHR26402:SF572 1 133 5.4E-23 T 22-04-2016 TOLA_RS01425 6365087d913e5a6d4c4f7320c4b01c7f 225 Gene3D G3DSA:3.20.20.450 5 215 6.9E-15 T 22-04-2016 IPR001633 EAL domain TOLA_RS01425 6365087d913e5a6d4c4f7320c4b01c7f 225 Pfam PF00563 EAL domain 9 214 2.0E-17 T 22-04-2016 IPR001633 EAL domain TOLA_RS01425 6365087d913e5a6d4c4f7320c4b01c7f 225 SMART SM00052 1 221 0.0046 T 22-04-2016 IPR001633 EAL domain TOLA_RS01425 6365087d913e5a6d4c4f7320c4b01c7f 225 SUPERFAMILY SSF141868 4 214 1.96E-20 T 22-04-2016 IPR001633 EAL domain TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 PANTHER PTHR13696:SF5 1 260 1.5E-147 T 22-04-2016 TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 Hamap MF_00533 Nitrogenase iron protein [nifH]. 3 276 52.019 T 22-04-2016 IPR005977 Nitrogenase iron protein NifH GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 ProSitePatterns PS00746 NifH/frxC family signature 1. 88 100 - T 22-04-2016 IPR030655 NifH/chlL conserved site TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 PRINTS PR00091 Nitrogenase component II signature 31 46 4.0E-37 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 PRINTS PR00091 Nitrogenase component II signature 86 100 4.0E-37 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 PRINTS PR00091 Nitrogenase component II signature 125 140 4.0E-37 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 PRINTS PR00091 Nitrogenase component II signature 9 22 4.0E-37 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 SUPERFAMILY SSF52540 7 280 6.19E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 PIRSF PIRSF000363 2 278 1.7E-124 T 22-04-2016 IPR000392 Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL GO:0005524|GO:0016491|GO:0055114 TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 PANTHER PTHR13696 1 260 1.5E-147 T 22-04-2016 TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 Gene3D G3DSA:3.40.50.300 7 272 2.6E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 ProSitePatterns PS00692 NifH/frxC family signature 2. 126 139 - T 22-04-2016 IPR030655 NifH/chlL conserved site TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 TIGRFAM TIGR01287 nifH: nitrogenase iron protein 4 278 1.2E-143 T 22-04-2016 IPR005977 Nitrogenase iron protein NifH GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 TOLA_RS03350 06b962a20226a9e4cb53458dd4ccf0c1 295 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 4 275 9.3E-139 T 22-04-2016 TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 Pfam PF07729 FCD domain 99 226 3.2E-18 T 22-04-2016 IPR011711 GntR, C-terminal TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 Gene3D G3DSA:1.20.120.530 98 237 7.9E-20 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 PANTHER PTHR11751 9 77 1.9E-45 T 22-04-2016 TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 PANTHER PTHR11751 93 115 1.9E-45 T 22-04-2016 TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 PANTHER PTHR11751:SF355 9 77 1.9E-45 T 22-04-2016 TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 PANTHER PTHR11751:SF355 93 115 1.9E-45 T 22-04-2016 TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 SMART SM00345 15 74 1.3E-26 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 3.0E-9 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 3.0E-9 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 Gene3D G3DSA:1.10.10.10 8 76 3.8E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 SUPERFAMILY SSF48008 96 235 4.97E-21 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 SMART SM00895 99 227 1.1E-16 T 22-04-2016 IPR011711 GntR, C-terminal TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 SUPERFAMILY SSF46785 9 76 5.35E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13105 80f6bbdd22b2ae6ccb91b653e82a937e 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 5.1E-23 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS07920 696e6667cd91e09ca7000823fa030fd6 232 PANTHER PTHR32119 1 227 1.4E-109 T 22-04-2016 TOLA_RS07920 696e6667cd91e09ca7000823fa030fd6 232 SMART SM00934 5 227 6.6E-97 T 22-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS07920 696e6667cd91e09ca7000823fa030fd6 232 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 3 232 39.097 T 22-04-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS07920 696e6667cd91e09ca7000823fa030fd6 232 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 227 1.1E-58 T 22-04-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS07920 696e6667cd91e09ca7000823fa030fd6 232 Gene3D G3DSA:3.20.20.70 3 228 5.8E-85 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS07920 696e6667cd91e09ca7000823fa030fd6 232 PANTHER PTHR32119:SF2 1 227 1.4E-109 T 22-04-2016 TOLA_RS07920 696e6667cd91e09ca7000823fa030fd6 232 SUPERFAMILY SSF51366 1 228 5.89E-74 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TOLA_RS07920 696e6667cd91e09ca7000823fa030fd6 232 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 57 70 - T 22-04-2016 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS07920 696e6667cd91e09ca7000823fa030fd6 232 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 5 227 2.1E-52 T 22-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 PANTHER PTHR24567:SF27 1 209 2.3E-149 T 22-04-2016 TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 SUPERFAMILY SSF51206 8 139 5.37E-34 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 Gene3D G3DSA:2.60.120.10 6 145 1.1E-41 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 71 91 - T 22-04-2016 IPR018488 Cyclic nucleotide-binding, conserved site TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 SMART SM00419 162 210 1.5E-15 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 SMART SM00100 2 124 1.1E-25 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 30 46 - T 22-04-2016 IPR018488 Cyclic nucleotide-binding, conserved site TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 Pfam PF00325 Bacterial regulatory proteins, crp family 168 199 1.0E-14 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 PANTHER PTHR24567 1 209 2.3E-149 T 22-04-2016 TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 Pfam PF00027 Cyclic nucleotide-binding domain 23 111 1.5E-22 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 ProSitePatterns PS00042 Crp-type HTH domain signature. 170 193 - T 22-04-2016 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 Gene3D G3DSA:1.10.10.10 146 209 5.8E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 SUPERFAMILY SSF46785 141 209 1.39E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 168 184 2.6E-10 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TOLA_RS14065 85d880d1b0f7741c0160ceb15036adb8 212 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 184 199 2.6E-10 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 11 71 3.4E-8 T 22-04-2016 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 Pfam PF00702 haloacid dehalogenase-like hydrolase 479 696 6.7E-44 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PRINTS PR00943 Copper-transporting ATPase signature 466 481 2.8E-6 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PRINTS PR00943 Copper-transporting ATPase signature 406 420 2.8E-6 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PRINTS PR00943 Copper-transporting ATPase signature 253 272 2.8E-6 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PRINTS PR00943 Copper-transporting ATPase signature 205 224 2.8E-6 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PRINTS PR00943 Copper-transporting ATPase signature 716 730 2.8E-6 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PRINTS PR00943 Copper-transporting ATPase signature 659 676 2.8E-6 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 Gene3D G3DSA:3.40.50.1000 610 750 7.9E-57 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 Gene3D G3DSA:3.40.50.1000 454 499 7.9E-57 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 220 783 1.1E-184 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 Gene3D G3DSA:2.70.150.10 218 383 6.2E-27 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 256 761 1.2E-88 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 Gene3D G3DSA:3.30.70.100 4 71 3.2E-20 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 SUPERFAMILY SSF55008 4 71 9.16E-17 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 Gene3D G3DSA:3.30.70.100 74 150 1.2E-20 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 SUPERFAMILY SSF81665 384 477 3.01E-13 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 SUPERFAMILY SSF81665 252 287 3.01E-13 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 SUPERFAMILY SSF81665 735 778 3.01E-13 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 202 784 7.0E-172 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 ProSitePatterns PS01047 Heavy-metal-associated domain. 80 109 - T 22-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 ProSitePatterns PS01047 Heavy-metal-associated domain. 13 42 - T 22-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 SUPERFAMILY SSF81653 286 382 1.31E-24 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 Pfam PF00122 E1-E2 ATPase 255 474 2.1E-65 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 485 491 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 Gene3D G3DSA:3.40.1110.10 502 609 6.1E-9 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 Pfam PF00403 Heavy-metal-associated domain 12 69 7.1E-13 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 Pfam PF00403 Heavy-metal-associated domain 77 137 9.2E-13 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PANTHER PTHR24093:SF332 7 796 4.5E-259 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 629 639 8.0E-27 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 483 497 8.0E-27 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 607 618 8.0E-27 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 682 701 8.0E-27 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 705 717 8.0E-27 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 333 347 8.0E-27 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 SUPERFAMILY SSF55008 74 142 7.2E-17 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 PANTHER PTHR24093 7 796 4.5E-259 T 22-04-2016 TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 SUPERFAMILY SSF56784 604 782 3.0E-58 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS03040 defdbe4ed9ae61b08f9d7f4a4f438aa8 797 SUPERFAMILY SSF56784 481 574 3.0E-58 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS15990 b1a7edd1c05440ae45163c2ca4eede1d 430 Gene3D G3DSA:3.40.50.300 6 192 8.5E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15990 b1a7edd1c05440ae45163c2ca4eede1d 430 PANTHER PTHR21343:SF6 2 428 7.1E-121 T 22-04-2016 TOLA_RS15990 b1a7edd1c05440ae45163c2ca4eede1d 430 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 11 420 9.1E-82 T 22-04-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 TOLA_RS15990 b1a7edd1c05440ae45163c2ca4eede1d 430 Gene3D G3DSA:3.40.50.880 239 421 1.5E-23 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS15990 b1a7edd1c05440ae45163c2ca4eede1d 430 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 11 159 3.2E-17 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TOLA_RS15990 b1a7edd1c05440ae45163c2ca4eede1d 430 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 240 417 8.9E-30 T 22-04-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 TOLA_RS15990 b1a7edd1c05440ae45163c2ca4eede1d 430 SUPERFAMILY SSF52540 8 193 6.42E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15990 b1a7edd1c05440ae45163c2ca4eede1d 430 PANTHER PTHR21343 2 428 7.1E-121 T 22-04-2016 TOLA_RS15990 b1a7edd1c05440ae45163c2ca4eede1d 430 SUPERFAMILY SSF52317 236 428 3.64E-29 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS06495 a17dc546ab5d5d9e5027b0dde3b609c6 491 Pfam PF01384 Phosphate transporter family 30 478 9.7E-82 T 22-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 TOLA_RS06495 a17dc546ab5d5d9e5027b0dde3b609c6 491 PANTHER PTHR11101 2 483 9.4E-207 T 22-04-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 TOLA_RS06495 a17dc546ab5d5d9e5027b0dde3b609c6 491 PRINTS PR00173 Glutamate-aspartate symporter signature 156 176 9.1E-6 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS06495 a17dc546ab5d5d9e5027b0dde3b609c6 491 PRINTS PR00173 Glutamate-aspartate symporter signature 198 223 9.1E-6 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS06495 a17dc546ab5d5d9e5027b0dde3b609c6 491 PRINTS PR00173 Glutamate-aspartate symporter signature 395 421 9.1E-6 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS06495 a17dc546ab5d5d9e5027b0dde3b609c6 491 PRINTS PR00173 Glutamate-aspartate symporter signature 113 133 9.1E-6 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS06495 a17dc546ab5d5d9e5027b0dde3b609c6 491 PANTHER PTHR11101:SF59 2 483 9.4E-207 T 22-04-2016 TOLA_RS08060 312c2331f6d7085b5f6a1222da7ef980 183 Gene3D G3DSA:3.90.79.10 4 176 2.8E-48 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS08060 312c2331f6d7085b5f6a1222da7ef980 183 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TOLA_RS08060 312c2331f6d7085b5f6a1222da7ef980 183 PANTHER PTHR11839:SF9 1 175 5.8E-37 T 22-04-2016 TOLA_RS08060 312c2331f6d7085b5f6a1222da7ef980 183 SUPERFAMILY SSF55811 4 175 2.03E-37 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS08060 312c2331f6d7085b5f6a1222da7ef980 183 PANTHER PTHR11839 1 175 5.8E-37 T 22-04-2016 TOLA_RS08060 312c2331f6d7085b5f6a1222da7ef980 183 Pfam PF00293 NUDIX domain 42 153 7.1E-14 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TOLA_RS08775 b209beeb48ff59ed5ab9eed024a70d3e 327 SUPERFAMILY SSF55681 92 327 1.09E-81 T 22-04-2016 TOLA_RS08775 b209beeb48ff59ed5ab9eed024a70d3e 327 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 39 327 2.5E-116 T 22-04-2016 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TOLA_RS08775 b209beeb48ff59ed5ab9eed024a70d3e 327 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 326 49.149 T 22-04-2016 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 TOLA_RS08775 b209beeb48ff59ed5ab9eed024a70d3e 327 PANTHER PTHR11538 90 327 6.5E-121 T 22-04-2016 TOLA_RS08775 b209beeb48ff59ed5ab9eed024a70d3e 327 PANTHER PTHR11538 43 52 6.5E-121 T 22-04-2016 TOLA_RS08775 b209beeb48ff59ed5ab9eed024a70d3e 327 SUPERFAMILY SSF46589 12 99 7.85E-23 T 22-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 TOLA_RS08775 b209beeb48ff59ed5ab9eed024a70d3e 327 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 87 1.7E-24 T 22-04-2016 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TOLA_RS08775 b209beeb48ff59ed5ab9eed024a70d3e 327 Pfam PF01409 tRNA synthetases class II core domain (F) 92 326 2.2E-107 T 22-04-2016 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TOLA_RS08775 b209beeb48ff59ed5ab9eed024a70d3e 327 Gene3D G3DSA:3.30.930.10 10 327 1.1E-134 T 22-04-2016 TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 SUPERFAMILY SSF56059 82 346 1.4E-66 T 22-04-2016 TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 320 3.3E-72 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 SMART SM00878 334 440 5.2E-61 T 22-04-2016 IPR005482 Biotin carboxylase, C-terminal TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 SUPERFAMILY SSF52440 1 112 2.73E-44 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 SUPERFAMILY SSF51246 329 446 1.62E-42 T 22-04-2016 IPR011054 Rudiment single hybrid motif TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 284 291 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 Gene3D G3DSA:3.40.50.20 2 128 9.3E-50 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 Gene3D G3DSA:3.30.1490.20 129 200 2.8E-26 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 PANTHER PTHR18866:SF111 1 467 1.9E-296 T 22-04-2016 TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 Pfam PF02785 Biotin carboxylase C-terminal domain 334 440 1.3E-39 T 22-04-2016 IPR005482 Biotin carboxylase, C-terminal TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 Gene3D G3DSA:3.30.470.20 203 446 7.5E-95 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 1.1E-41 T 22-04-2016 IPR005481 Biotin carboxylase-like, N-terminal domain TOLA_RS09375 bbd3879445444005872e92efb5a36a80 471 PANTHER PTHR18866 1 467 1.9E-296 T 22-04-2016 TOLA_RS06820 3f802c9981645115ce368f0ba98a2fca 373 PANTHER PTHR30193 3 71 3.0E-93 T 22-04-2016 TOLA_RS06820 3f802c9981645115ce368f0ba98a2fca 373 PANTHER PTHR30193 129 373 3.0E-93 T 22-04-2016 TOLA_RS06820 3f802c9981645115ce368f0ba98a2fca 373 Gene3D G3DSA:1.10.3720.10 139 371 1.4E-63 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06820 3f802c9981645115ce368f0ba98a2fca 373 PANTHER PTHR30193:SF6 3 71 3.0E-93 T 22-04-2016 TOLA_RS06820 3f802c9981645115ce368f0ba98a2fca 373 PANTHER PTHR30193:SF6 129 373 3.0E-93 T 22-04-2016 TOLA_RS06820 3f802c9981645115ce368f0ba98a2fca 373 SUPERFAMILY SSF161098 139 361 3.01E-59 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06820 3f802c9981645115ce368f0ba98a2fca 373 Gene3D G3DSA:1.20.58.370 25 59 2.8E-4 T 22-04-2016 TOLA_RS06820 3f802c9981645115ce368f0ba98a2fca 373 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 166 371 1.7E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06820 3f802c9981645115ce368f0ba98a2fca 373 SUPERFAMILY SSF161098 25 83 5.1E-6 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05860 a5bc5e306c919ef87c32d2031b403411 165 SUPERFAMILY SSF102712 55 131 1.09E-6 T 22-04-2016 TOLA_RS05860 a5bc5e306c919ef87c32d2031b403411 165 TIGRFAM TIGR00608 radc: DNA repair protein RadC 24 164 1.6E-45 T 22-04-2016 IPR001405 RadC protein TOLA_RS05860 a5bc5e306c919ef87c32d2031b403411 165 Gene3D G3DSA:3.40.140.10 43 164 9.9E-46 T 22-04-2016 TOLA_RS05860 a5bc5e306c919ef87c32d2031b403411 165 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 114 119 - T 22-04-2016 IPR020891 Uncharacterised protein family UPF0758, conserved site TOLA_RS05860 a5bc5e306c919ef87c32d2031b403411 165 PANTHER PTHR30471:SF5 26 165 1.4E-67 T 22-04-2016 TOLA_RS05860 a5bc5e306c919ef87c32d2031b403411 165 PANTHER PTHR30471 26 165 1.4E-67 T 22-04-2016 TOLA_RS05860 a5bc5e306c919ef87c32d2031b403411 165 Pfam PF04002 RadC-like JAB domain 45 164 6.1E-42 T 22-04-2016 IPR025657 RadC-like JAB domain TOLA_RS11915 e221e6e77890e81da92fb5a01b0ce926 387 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 19 35 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 TOLA_RS11915 e221e6e77890e81da92fb5a01b0ce926 387 PANTHER PTHR10277 9 380 7.6E-131 T 22-04-2016 TOLA_RS11915 e221e6e77890e81da92fb5a01b0ce926 387 Pfam PF00682 HMGL-like 12 268 4.7E-77 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 TOLA_RS11915 e221e6e77890e81da92fb5a01b0ce926 387 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 22-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 TOLA_RS11915 e221e6e77890e81da92fb5a01b0ce926 387 SUPERFAMILY SSF51569 9 286 3.11E-79 T 22-04-2016 TOLA_RS11915 e221e6e77890e81da92fb5a01b0ce926 387 TIGRFAM TIGR02660 nifV_homocitr: homocitrate synthase 12 373 1.4E-161 T 22-04-2016 IPR013477 Homocitrate synthase NifV-type GO:0004410|GO:0051188 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 TOLA_RS11915 e221e6e77890e81da92fb5a01b0ce926 387 Gene3D G3DSA:3.20.20.70 8 342 2.0E-100 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS11915 e221e6e77890e81da92fb5a01b0ce926 387 PANTHER PTHR10277:SF45 9 380 7.6E-131 T 22-04-2016 TOLA_RS08200 eba018ebfb51d6e26a5dcf963eead016 650 Gene3D G3DSA:3.40.50.300 1 355 9.9E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08200 eba018ebfb51d6e26a5dcf963eead016 650 Pfam PF13175 AAA ATPase domain 1 55 9.7E-12 T 22-04-2016 TOLA_RS08200 eba018ebfb51d6e26a5dcf963eead016 650 Pfam PF13175 AAA ATPase domain 141 342 2.6E-22 T 22-04-2016 TOLA_RS08200 eba018ebfb51d6e26a5dcf963eead016 650 SUPERFAMILY SSF52540 1 120 1.91E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08200 eba018ebfb51d6e26a5dcf963eead016 650 SUPERFAMILY SSF52540 150 348 1.91E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08200 eba018ebfb51d6e26a5dcf963eead016 650 PANTHER PTHR32182 1 414 5.9E-23 T 22-04-2016 TOLA_RS08200 eba018ebfb51d6e26a5dcf963eead016 650 PANTHER PTHR32182:SF7 1 414 5.9E-23 T 22-04-2016 TOLA_RS02690 76b06bcea2b18c4d73f18df7322dfb8c 586 SUPERFAMILY SSF56519 60 231 8.89E-41 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TOLA_RS02690 76b06bcea2b18c4d73f18df7322dfb8c 586 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 217 1.7E-14 T 22-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TOLA_RS02690 76b06bcea2b18c4d73f18df7322dfb8c 586 Pfam PF00905 Penicillin binding protein transpeptidase domain 257 550 3.6E-76 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TOLA_RS02690 76b06bcea2b18c4d73f18df7322dfb8c 586 PANTHER PTHR30627:SF1 5 578 1.1E-209 T 22-04-2016 TOLA_RS02690 76b06bcea2b18c4d73f18df7322dfb8c 586 Gene3D G3DSA:3.90.1310.10 138 238 6.2E-28 T 22-04-2016 TOLA_RS02690 76b06bcea2b18c4d73f18df7322dfb8c 586 SUPERFAMILY SSF56601 233 562 2.73E-91 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS02690 76b06bcea2b18c4d73f18df7322dfb8c 586 Gene3D G3DSA:3.40.710.10 239 560 1.5E-89 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS02690 76b06bcea2b18c4d73f18df7322dfb8c 586 PANTHER PTHR30627 5 578 1.1E-209 T 22-04-2016 TOLA_RS15460 6311598add494bbd75de15fe1ac97e39 322 PIRSF PIRSF003097 24 318 1.2E-72 T 22-04-2016 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 TOLA_RS15460 6311598add494bbd75de15fe1ac97e39 322 Pfam PF02687 FtsX-like permease family 199 314 2.3E-9 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 TOLA_RS00050 8e5bbc7f2208202d39f21611e7339de6 191 SUPERFAMILY SSF48150 4 184 1.49E-77 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 TOLA_RS00050 8e5bbc7f2208202d39f21611e7339de6 191 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 4 180 2.6E-72 T 22-04-2016 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 TOLA_RS00050 8e5bbc7f2208202d39f21611e7339de6 191 Gene3D G3DSA:1.10.340.30 4 183 1.3E-80 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 TOLA_RS00050 8e5bbc7f2208202d39f21611e7339de6 191 Pfam PF03352 Methyladenine glycosylase 7 181 4.9E-77 T 22-04-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 TOLA_RS00050 8e5bbc7f2208202d39f21611e7339de6 191 PANTHER PTHR30037 1 184 1.2E-102 T 22-04-2016 TOLA_RS00050 8e5bbc7f2208202d39f21611e7339de6 191 PANTHER PTHR30037:SF4 1 184 1.2E-102 T 22-04-2016 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 PANTHER PTHR11117 1 287 4.0E-195 T 22-04-2016 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 PIRSF PIRSF001553 1 290 2.2E-134 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 Gene3D G3DSA:3.40.50.720 2 119 2.7E-57 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 Gene3D G3DSA:3.40.50.261 120 287 9.5E-76 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 SMART SM00881 4 100 8.1E-38 T 22-04-2016 IPR003781 CoA-binding GO:0048037 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.4E-40 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.4E-40 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.4E-40 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.4E-40 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 Pfam PF02629 CoA binding domain 6 99 3.7E-32 T 22-04-2016 IPR003781 CoA-binding GO:0048037 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 22-04-2016 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 SUPERFAMILY SSF52210 123 286 4.84E-56 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 SUPERFAMILY SSF51735 1 122 3.41E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 286 1.9E-145 T 22-04-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 TOLA_RS11300 bbd77e266cc25e9a5091545b69cf3603 291 Pfam PF00549 CoA-ligase 151 270 1.1E-20 T 22-04-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS06390 edc3ab90bce34d09626a45e69e0eaaee 318 SUPERFAMILY SSF52440 3 123 2.22E-46 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS06390 edc3ab90bce34d09626a45e69e0eaaee 318 Hamap MF_00162 Glutathione synthetase [gshB]. 1 317 175.031 T 22-04-2016 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3|UniPathway: UPA00142 TOLA_RS06390 edc3ab90bce34d09626a45e69e0eaaee 318 PANTHER PTHR21621:SF4 1 315 7.4E-166 T 22-04-2016 TOLA_RS06390 edc3ab90bce34d09626a45e69e0eaaee 318 SUPERFAMILY SSF56059 124 313 1.06E-58 T 22-04-2016 TOLA_RS06390 edc3ab90bce34d09626a45e69e0eaaee 318 TIGRFAM TIGR01380 glut_syn: glutathione synthase 3 312 2.1E-136 T 22-04-2016 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3|UniPathway: UPA00142 TOLA_RS06390 edc3ab90bce34d09626a45e69e0eaaee 318 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 125 297 2.2E-78 T 22-04-2016 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3|UniPathway: UPA00142 TOLA_RS06390 edc3ab90bce34d09626a45e69e0eaaee 318 Gene3D G3DSA:3.30.1490.20 138 192 6.7E-31 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS06390 edc3ab90bce34d09626a45e69e0eaaee 318 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 3 121 8.8E-47 T 22-04-2016 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3|UniPathway: UPA00142 TOLA_RS06390 edc3ab90bce34d09626a45e69e0eaaee 318 Gene3D G3DSA:3.30.470.20 193 300 2.1E-49 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS06390 edc3ab90bce34d09626a45e69e0eaaee 318 PANTHER PTHR21621 1 315 7.4E-166 T 22-04-2016 TOLA_RS06390 edc3ab90bce34d09626a45e69e0eaaee 318 Gene3D G3DSA:3.40.50.20 3 130 5.7E-55 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS16175 8929c0e0dfd19fcdc566ecb600f8faf3 101 PANTHER PTHR33154 1 101 1.5E-22 T 22-04-2016 TOLA_RS16175 8929c0e0dfd19fcdc566ecb600f8faf3 101 Pfam PF12840 Helix-turn-helix domain 7 78 2.1E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS16175 8929c0e0dfd19fcdc566ecb600f8faf3 101 SUPERFAMILY SSF46785 3 97 2.16E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS16175 8929c0e0dfd19fcdc566ecb600f8faf3 101 SMART SM00418 8 94 2.8E-11 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TOLA_RS16175 8929c0e0dfd19fcdc566ecb600f8faf3 101 Gene3D G3DSA:1.10.10.10 2 99 3.3E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS12915 b6a2b65485ca6e383a35912a19b5748c 160 Pfam PF00583 Acetyltransferase (GNAT) family 59 140 1.8E-16 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS12915 b6a2b65485ca6e383a35912a19b5748c 160 Gene3D G3DSA:3.40.630.30 17 141 6.5E-26 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS12915 b6a2b65485ca6e383a35912a19b5748c 160 PANTHER PTHR10545 62 140 4.6E-15 T 22-04-2016 TOLA_RS12915 b6a2b65485ca6e383a35912a19b5748c 160 SUPERFAMILY SSF55729 16 141 3.11E-26 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS07830 2448c280f3627f0f96d8ab95003993aa 329 Gene3D G3DSA:3.40.50.720 138 303 5.2E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS07830 2448c280f3627f0f96d8ab95003993aa 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 297 1.5E-52 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TOLA_RS07830 2448c280f3627f0f96d8ab95003993aa 329 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 328 4.7E-27 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 TOLA_RS07830 2448c280f3627f0f96d8ab95003993aa 329 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 194 216 - T 22-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TOLA_RS07830 2448c280f3627f0f96d8ab95003993aa 329 SUPERFAMILY SSF52283 2 135 4.35E-39 T 22-04-2016 TOLA_RS07830 2448c280f3627f0f96d8ab95003993aa 329 SUPERFAMILY SSF51735 102 298 3.23E-52 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS07830 2448c280f3627f0f96d8ab95003993aa 329 PANTHER PTHR10996:SF161 1 329 3.8E-163 T 22-04-2016 TOLA_RS07830 2448c280f3627f0f96d8ab95003993aa 329 Gene3D G3DSA:3.40.50.720 1 137 1.4E-45 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS07830 2448c280f3627f0f96d8ab95003993aa 329 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 22-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TOLA_RS07830 2448c280f3627f0f96d8ab95003993aa 329 PANTHER PTHR10996 1 329 3.8E-163 T 22-04-2016 TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 PANTHER PTHR13691 1 273 2.3E-145 T 22-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 272 2.5E-130 T 22-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 PANTHER PTHR13691:SF5 1 273 2.3E-145 T 22-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 249 2.5E-54 T 22-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 6.4E-34 T 22-04-2016 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 47.236 T 22-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 SUPERFAMILY SSF50249 2 125 2.36E-50 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 SUPERFAMILY SSF50104 127 269 7.82E-58 T 22-04-2016 IPR008991 Translation protein SH3-like domain TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 Gene3D G3DSA:2.30.30.30 119 195 1.2E-32 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 Gene3D G3DSA:4.10.950.10 196 272 1.3E-34 T 22-04-2016 IPR014726 Ribosomal protein L2, domain 3 TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 SMART SM01382 124 251 1.4E-88 T 22-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 PIRSF PIRSF002158 11 273 4.0E-98 T 22-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 Gene3D G3DSA:2.40.50.140 1 114 3.2E-51 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS00535 7f300a725cbab5d40187c084fbd4dbbb 273 SMART SM01383 42 118 4.2E-46 T 22-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS11110 c58ee754474481b399b5485a1344b216 350 Pfam PF02618 YceG-like family 62 344 3.9E-82 T 22-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like TOLA_RS11110 c58ee754474481b399b5485a1344b216 350 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 26 347 7.0E-93 T 22-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like TOLA_RS11110 c58ee754474481b399b5485a1344b216 350 PANTHER PTHR30518 8 347 1.8E-85 T 22-04-2016 TOLA_RS11110 c58ee754474481b399b5485a1344b216 350 Gene3D G3DSA:3.30.160.60 318 348 1.3E-15 T 22-04-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 TOLA_RS11110 c58ee754474481b399b5485a1344b216 350 Gene3D G3DSA:3.30.160.60 88 125 1.9E-17 T 22-04-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 TOLA_RS11110 c58ee754474481b399b5485a1344b216 350 PANTHER PTHR30518:SF2 8 347 1.8E-85 T 22-04-2016 TOLA_RS15270 7bf93d8663d4e999969ae872e1e9768e 343 Pfam PF00494 Squalene/phytoene synthase 11 295 1.4E-45 T 22-04-2016 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 TOLA_RS15270 7bf93d8663d4e999969ae872e1e9768e 343 Gene3D G3DSA:1.10.600.10 7 320 3.6E-63 T 22-04-2016 IPR008949 Isoprenoid synthase domain TOLA_RS15270 7bf93d8663d4e999969ae872e1e9768e 343 SUPERFAMILY SSF48576 7 308 1.44E-50 T 22-04-2016 IPR008949 Isoprenoid synthase domain TOLA_RS15270 7bf93d8663d4e999969ae872e1e9768e 343 PANTHER PTHR11626 8 302 4.0E-44 T 22-04-2016 TOLA_RS15270 7bf93d8663d4e999969ae872e1e9768e 343 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 149 164 - T 22-04-2016 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 TOLA_RS15270 7bf93d8663d4e999969ae872e1e9768e 343 PANTHER PTHR11626:SF4 8 302 4.0E-44 T 22-04-2016 TOLA_RS09975 808c6e0511a5a766ed6cc4ca7b67be7e 347 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS09975 808c6e0511a5a766ed6cc4ca7b67be7e 347 Pfam PF00005 ABC transporter 25 166 1.0E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS09975 808c6e0511a5a766ed6cc4ca7b67be7e 347 Gene3D G3DSA:3.40.50.300 5 239 5.1E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09975 808c6e0511a5a766ed6cc4ca7b67be7e 347 SMART SM00382 33 216 1.9E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS09975 808c6e0511a5a766ed6cc4ca7b67be7e 347 SUPERFAMILY SSF50331 241 345 9.28E-10 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS09975 808c6e0511a5a766ed6cc4ca7b67be7e 347 PANTHER PTHR24220:SF481 9 296 1.5E-119 T 22-04-2016 TOLA_RS09975 808c6e0511a5a766ed6cc4ca7b67be7e 347 SUPERFAMILY SSF52540 8 246 5.32E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09975 808c6e0511a5a766ed6cc4ca7b67be7e 347 Pfam PF08402 TOBE domain 270 345 2.2E-10 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 TOLA_RS09975 808c6e0511a5a766ed6cc4ca7b67be7e 347 Gene3D G3DSA:2.40.50.140 279 337 4.3E-4 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS09975 808c6e0511a5a766ed6cc4ca7b67be7e 347 PANTHER PTHR24220 9 296 1.5E-119 T 22-04-2016 TOLA_RS14670 78cb3f099be4442bc083d95ee7418dc8 407 TIGRFAM TIGR04370 glyco_rpt_poly: oligosaccharide repeat unit polymerase 13 393 8.4E-50 T 22-04-2016 TOLA_RS14670 78cb3f099be4442bc083d95ee7418dc8 407 ProDom PD140121 POLYMERASE O-ANTIGEN TRANSMEMBRANE POLYSACCHARIDE WZY REPEAT MEMBRANE UNIT OLIGOSACCHARIDE CPS6AI 188 393 1.0E-42 T 22-04-2016 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 SUPERFAMILY SSF48557 3 456 4.56E-138 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 TIGRFAM TIGR00838 argH: argininosuccinate lyase 3 456 2.1E-199 T 22-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 Gene3D G3DSA:1.10.275.10 1 107 1.2E-36 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 Pfam PF14698 Argininosuccinate lyase C-terminal 364 431 2.3E-23 T 22-04-2016 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 PANTHER PTHR11444:SF3 3 456 5.3E-231 T 22-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 Pfam PF00206 Lyase 6 301 3.3E-90 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 Hamap MF_00006 Argininosuccinate lyase [argH]. 2 454 40.373 T 22-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 Gene3D G3DSA:1.10.40.30 376 431 9.9E-29 T 22-04-2016 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 3.6E-29 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 3.6E-29 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 3.6E-29 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 3.6E-29 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 Gene3D G3DSA:1.20.200.10 108 375 2.9E-100 T 22-04-2016 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 PANTHER PTHR11444 3 456 5.3E-231 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 9.8E-67 T 22-04-2016 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 9.8E-67 T 22-04-2016 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 9.8E-67 T 22-04-2016 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 9.8E-67 T 22-04-2016 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 9.8E-67 T 22-04-2016 TOLA_RS00510 e9d05ea4043ea38375ab0cf2e291ab64 461 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 9.8E-67 T 22-04-2016 TOLA_RS02235 7d2e9e19624d9fbb55d2791a361666de 281 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 7 275 1.6E-94 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS02235 7d2e9e19624d9fbb55d2791a361666de 281 PIRSF PIRSF005917 1 279 4.7E-104 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS02235 7d2e9e19624d9fbb55d2791a361666de 281 PANTHER PTHR21091 7 242 4.0E-91 T 22-04-2016 TOLA_RS02235 7d2e9e19624d9fbb55d2791a361666de 281 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 84 95 - T 22-04-2016 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS02235 7d2e9e19624d9fbb55d2791a361666de 281 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 6 226 37.65 T 22-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS02235 7d2e9e19624d9fbb55d2791a361666de 281 SUPERFAMILY SSF53790 5 224 4.97E-84 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS02235 7d2e9e19624d9fbb55d2791a361666de 281 PANTHER PTHR21091:SF18 7 242 4.0E-91 T 22-04-2016 TOLA_RS02235 7d2e9e19624d9fbb55d2791a361666de 281 Gene3D G3DSA:3.40.1010.10 7 113 1.4E-15 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 TOLA_RS02235 7d2e9e19624d9fbb55d2791a361666de 281 Gene3D G3DSA:3.30.950.10 114 227 1.6E-42 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 TOLA_RS02235 7d2e9e19624d9fbb55d2791a361666de 281 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 204 1.8E-31 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 Gene3D G3DSA:3.20.20.20 366 638 6.0E-113 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 Pfam PF02607 B12 binding domain 663 734 3.4E-24 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain TOLA_RS10810 0602068229c72508ed199857479658bd 1237 Pfam PF02574 Homocysteine S-methyltransferase 19 327 2.1E-93 T 22-04-2016 IPR003726 Homocysteine-binding domain TOLA_RS10810 0602068229c72508ed199857479658bd 1237 PANTHER PTHR21091:SF111 1 404 3.8E-169 T 22-04-2016 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 SUPERFAMILY SSF52242 746 896 9.55E-46 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 SUPERFAMILY SSF51717 358 632 3.92E-87 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 SUPERFAMILY SSF82282 9 401 3.14E-119 T 22-04-2016 IPR003726 Homocysteine-binding domain TOLA_RS10810 0602068229c72508ed199857479658bd 1237 SUPERFAMILY SSF56507 904 1236 7.46E-129 T 22-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 Gene3D G3DSA:3.40.50.280 747 896 1.6E-66 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 Pfam PF00809 Pterin binding enzyme 362 600 3.5E-60 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 PANTHER PTHR21091 1 404 3.8E-169 T 22-04-2016 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 TIGRFAM TIGR02082 metH: methionine synthase 14 1202 0.0 T 22-04-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 Pfam PF02310 B12 binding domain 750 843 3.9E-19 T 22-04-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 SUPERFAMILY SSF47644 654 741 6.28E-29 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain TOLA_RS10810 0602068229c72508ed199857479658bd 1237 Gene3D G3DSA:3.10.196.10 960 1236 8.7E-111 T 22-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 Gene3D G3DSA:3.20.20.330 6 365 2.7E-129 T 22-04-2016 IPR003726 Homocysteine-binding domain TOLA_RS10810 0602068229c72508ed199857479658bd 1237 Gene3D G3DSA:1.10.1240.10 653 739 4.2E-39 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain TOLA_RS10810 0602068229c72508ed199857479658bd 1237 SMART SM01018 659 742 3.0E-44 T 22-04-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain TOLA_RS10810 0602068229c72508ed199857479658bd 1237 PIRSF PIRSF000381 3 1205 0.0 T 22-04-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 TOLA_RS10810 0602068229c72508ed199857479658bd 1237 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 941 1218 1.2E-121 T 22-04-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 TOLA_RS06120 7dcca61fbf9c1b77bbeac88245020406 91 PANTHER PTHR24220:SF565 1 83 5.5E-21 T 22-04-2016 TOLA_RS06120 7dcca61fbf9c1b77bbeac88245020406 91 PANTHER PTHR24220 1 83 5.5E-21 T 22-04-2016 TOLA_RS09370 98a6c9e5c476014d2a2db1e57f53285c 318 SUPERFAMILY SSF46785 5 85 4.84E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09370 98a6c9e5c476014d2a2db1e57f53285c 318 Pfam PF03466 LysR substrate binding domain 94 300 1.4E-53 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS09370 98a6c9e5c476014d2a2db1e57f53285c 318 PANTHER PTHR30126:SF5 7 315 2.0E-130 T 22-04-2016 TOLA_RS09370 98a6c9e5c476014d2a2db1e57f53285c 318 PANTHER PTHR30126 7 315 2.0E-130 T 22-04-2016 TOLA_RS09370 98a6c9e5c476014d2a2db1e57f53285c 318 Gene3D G3DSA:3.40.190.10 183 270 1.6E-24 T 22-04-2016 TOLA_RS09370 98a6c9e5c476014d2a2db1e57f53285c 318 Gene3D G3DSA:1.10.10.10 8 94 1.4E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09370 98a6c9e5c476014d2a2db1e57f53285c 318 SUPERFAMILY SSF53850 96 300 3.12E-47 T 22-04-2016 TOLA_RS09370 98a6c9e5c476014d2a2db1e57f53285c 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 5.8E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS09370 98a6c9e5c476014d2a2db1e57f53285c 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 5.8E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS09370 98a6c9e5c476014d2a2db1e57f53285c 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 5.8E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS09370 98a6c9e5c476014d2a2db1e57f53285c 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 4.5E-17 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS09370 98a6c9e5c476014d2a2db1e57f53285c 318 Gene3D G3DSA:3.40.190.10 97 182 8.0E-16 T 22-04-2016 TOLA_RS11150 97ebbdb923d9ec73ad1c184c8b66b270 54 PANTHER PTHR35534 1 54 1.1E-28 T 22-04-2016 TOLA_RS11150 97ebbdb923d9ec73ad1c184c8b66b270 54 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 3.0E-20 T 22-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 TOLA_RS11150 97ebbdb923d9ec73ad1c184c8b66b270 54 Pfam PF01783 Ribosomal L32p protein family 2 54 1.6E-20 T 22-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 TOLA_RS11150 97ebbdb923d9ec73ad1c184c8b66b270 54 SUPERFAMILY SSF57829 2 54 6.71E-19 T 22-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 TOLA_RS11150 97ebbdb923d9ec73ad1c184c8b66b270 54 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.952 T 22-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 TOLA_RS08605 f8a2870d6044daf9f1f38d86c56b58f2 168 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 4 65 2.0E-15 T 22-04-2016 TOLA_RS08605 f8a2870d6044daf9f1f38d86c56b58f2 168 Pfam PF00936 BMC domain 4 80 5.0E-20 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08605 f8a2870d6044daf9f1f38d86c56b58f2 168 SUPERFAMILY SSF143414 4 96 2.35E-21 T 22-04-2016 TOLA_RS08605 f8a2870d6044daf9f1f38d86c56b58f2 168 PANTHER PTHR33941:SF2 4 163 5.8E-45 T 22-04-2016 TOLA_RS08605 f8a2870d6044daf9f1f38d86c56b58f2 168 SMART SM00877 3 80 7.6E-21 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08605 f8a2870d6044daf9f1f38d86c56b58f2 168 PANTHER PTHR33941 4 163 5.8E-45 T 22-04-2016 TOLA_RS09170 52129b020e87dbca62ad14b5fae19cc9 362 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 194 350 6.4E-45 T 22-04-2016 IPR017516 AbrB duplication TOLA_RS09170 52129b020e87dbca62ad14b5fae19cc9 362 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 17 172 2.2E-41 T 22-04-2016 IPR017516 AbrB duplication TOLA_RS09170 52129b020e87dbca62ad14b5fae19cc9 362 PANTHER PTHR38457:SF1 9 360 8.1E-70 T 22-04-2016 TOLA_RS09170 52129b020e87dbca62ad14b5fae19cc9 362 PIRSF PIRSF038991 6 357 1.5E-84 T 22-04-2016 IPR007820 AbrB family GO:0010468|GO:0016021 TOLA_RS09170 52129b020e87dbca62ad14b5fae19cc9 362 Pfam PF05145 Putative ammonia monooxygenase 40 350 1.5E-96 T 22-04-2016 IPR007820 AbrB family GO:0010468|GO:0016021 TOLA_RS09170 52129b020e87dbca62ad14b5fae19cc9 362 PANTHER PTHR38457 9 360 8.1E-70 T 22-04-2016 TOLA_RS16280 2830e4d6403a63759e24d5add82e45d5 254 SMART SM00421 170 227 2.2E-18 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS16280 2830e4d6403a63759e24d5add82e45d5 254 ProSitePatterns PS00622 LuxR-type HTH domain signature. 187 214 - T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS16280 2830e4d6403a63759e24d5add82e45d5 254 Gene3D G3DSA:1.10.10.10 176 227 1.1E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS16280 2830e4d6403a63759e24d5add82e45d5 254 SUPERFAMILY SSF75516 14 168 4.18E-23 T 22-04-2016 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain TOLA_RS16280 2830e4d6403a63759e24d5add82e45d5 254 Gene3D G3DSA:3.30.450.80 14 175 9.6E-30 T 22-04-2016 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain TOLA_RS16280 2830e4d6403a63759e24d5add82e45d5 254 Pfam PF00196 Bacterial regulatory proteins, luxR family 172 224 1.1E-16 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS16280 2830e4d6403a63759e24d5add82e45d5 254 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 203 215 7.5E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS16280 2830e4d6403a63759e24d5add82e45d5 254 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 203 7.5E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS16280 2830e4d6403a63759e24d5add82e45d5 254 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 187 7.5E-10 T 22-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TOLA_RS16280 2830e4d6403a63759e24d5add82e45d5 254 Pfam PF03472 Autoinducer binding domain 23 147 2.0E-19 T 22-04-2016 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain TOLA_RS16280 2830e4d6403a63759e24d5add82e45d5 254 SUPERFAMILY SSF46894 162 228 2.04E-17 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TOLA_RS01460 f20cba42b1e2e6cbd8b126b461ac3707 545 PANTHER PTHR30462 2 545 2.1E-211 T 22-04-2016 TOLA_RS01460 f20cba42b1e2e6cbd8b126b461ac3707 545 Pfam PF02470 MlaD protein 283 388 1.2E-16 T 22-04-2016 IPR003399 Mce/MlaD TOLA_RS01460 f20cba42b1e2e6cbd8b126b461ac3707 545 Pfam PF02470 MlaD protein 158 216 1.3E-6 T 22-04-2016 IPR003399 Mce/MlaD TOLA_RS01460 f20cba42b1e2e6cbd8b126b461ac3707 545 Pfam PF02470 MlaD protein 40 131 3.1E-14 T 22-04-2016 IPR003399 Mce/MlaD TOLA_RS01460 f20cba42b1e2e6cbd8b126b461ac3707 545 PANTHER PTHR30462:SF2 2 545 2.1E-211 T 22-04-2016 TOLA_RS05275 9526dfccbbd4e524af8bcbf93a2151be 270 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 131 267 2.3E-42 T 22-04-2016 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05275 9526dfccbbd4e524af8bcbf93a2151be 270 PIRSF PIRSF000161 3 270 2.3E-88 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05275 9526dfccbbd4e524af8bcbf93a2151be 270 PANTHER PTHR20836:SF0 1 269 8.5E-100 T 22-04-2016 TOLA_RS05275 9526dfccbbd4e524af8bcbf93a2151be 270 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 5 268 34.595 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05275 9526dfccbbd4e524af8bcbf93a2151be 270 PANTHER PTHR20836 1 269 8.5E-100 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05275 9526dfccbbd4e524af8bcbf93a2151be 270 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 153 170 - T 22-04-2016 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05275 9526dfccbbd4e524af8bcbf93a2151be 270 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 5 128 1.5E-40 T 22-04-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05275 9526dfccbbd4e524af8bcbf93a2151be 270 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 5 267 9.1E-104 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05275 9526dfccbbd4e524af8bcbf93a2151be 270 SUPERFAMILY SSF51735 4 129 7.77E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS05275 9526dfccbbd4e524af8bcbf93a2151be 270 SUPERFAMILY SSF51735 239 269 7.77E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS05275 9526dfccbbd4e524af8bcbf93a2151be 270 Gene3D G3DSA:3.40.50.720 3 166 1.1E-60 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS05275 9526dfccbbd4e524af8bcbf93a2151be 270 SUPERFAMILY SSF55347 130 239 9.81E-38 T 22-04-2016 TOLA_RS10610 fe5a5b66c85328104e8c25c19d270317 438 Pfam PF03471 Transporter associated domain 345 424 5.8E-21 T 22-04-2016 IPR005170 Transporter-associated domain TOLA_RS10610 fe5a5b66c85328104e8c25c19d270317 438 SUPERFAMILY SSF56176 342 433 1.01E-21 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 TOLA_RS10610 fe5a5b66c85328104e8c25c19d270317 438 Gene3D G3DSA:3.10.580.10 197 324 8.9E-16 T 22-04-2016 TOLA_RS10610 fe5a5b66c85328104e8c25c19d270317 438 PANTHER PTHR22777 1 433 2.4E-176 T 22-04-2016 TOLA_RS10610 fe5a5b66c85328104e8c25c19d270317 438 Pfam PF01595 Domain of unknown function DUF21 5 196 3.3E-44 T 22-04-2016 IPR002550 Domain of unknown function DUF21 TOLA_RS10610 fe5a5b66c85328104e8c25c19d270317 438 Pfam PF00571 CBS domain 285 329 3.3E-4 T 22-04-2016 IPR000644 CBS domain TOLA_RS10610 fe5a5b66c85328104e8c25c19d270317 438 SUPERFAMILY SSF54631 198 333 1.26E-26 T 22-04-2016 TOLA_RS10610 fe5a5b66c85328104e8c25c19d270317 438 Gene3D G3DSA:3.30.465.10 325 424 2.1E-26 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 TOLA_RS10610 fe5a5b66c85328104e8c25c19d270317 438 PANTHER PTHR22777:SF8 1 433 2.4E-176 T 22-04-2016 TOLA_RS10610 fe5a5b66c85328104e8c25c19d270317 438 SMART SM01091 344 426 6.0E-27 T 22-04-2016 IPR005170 Transporter-associated domain TOLA_RS15650 2cf3c3b4f8cdc50dd31159c594b8dcce 278 Gene3D G3DSA:2.60.120.500 133 278 5.2E-76 T 22-04-2016 IPR027447 5-keto-4-deoxyuronate isomerase, C-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507|UniPathway: UPA00545 TOLA_RS15650 2cf3c3b4f8cdc50dd31159c594b8dcce 278 PIRSF PIRSF006625 1 278 2.3E-132 T 22-04-2016 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507|UniPathway: UPA00545 TOLA_RS15650 2cf3c3b4f8cdc50dd31159c594b8dcce 278 Gene3D G3DSA:2.60.120.520 20 132 5.4E-54 T 22-04-2016 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal domain KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507|UniPathway: UPA00545 TOLA_RS15650 2cf3c3b4f8cdc50dd31159c594b8dcce 278 PANTHER PTHR38461 1 278 1.5E-167 T 22-04-2016 TOLA_RS15650 2cf3c3b4f8cdc50dd31159c594b8dcce 278 Hamap MF_00687 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [kduI]. 1 278 55.533 T 22-04-2016 IPR007045 5-keto 4-deoxyuronate isomerase GO:0008697|GO:0045490 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507|UniPathway: UPA00545 TOLA_RS15650 2cf3c3b4f8cdc50dd31159c594b8dcce 278 Pfam PF04962 KduI/IolB family 63 273 8.1E-39 T 22-04-2016 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507|UniPathway: UPA00545 TOLA_RS15650 2cf3c3b4f8cdc50dd31159c594b8dcce 278 SUPERFAMILY SSF51182 1 262 4.6E-107 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS09455 ef0d64454c6347c3a87f4803a09192ee 520 PANTHER PTHR24220:SF327 263 501 2.9E-114 T 22-04-2016 TOLA_RS09455 ef0d64454c6347c3a87f4803a09192ee 520 SUPERFAMILY SSF161098 15 211 3.66E-36 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09455 ef0d64454c6347c3a87f4803a09192ee 520 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 218 4.1E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09455 ef0d64454c6347c3a87f4803a09192ee 520 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 115 1.1E-21 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 TOLA_RS09455 ef0d64454c6347c3a87f4803a09192ee 520 Gene3D G3DSA:3.40.50.300 257 497 1.5E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09455 ef0d64454c6347c3a87f4803a09192ee 520 PANTHER PTHR24220 263 501 2.9E-114 T 22-04-2016 TOLA_RS09455 ef0d64454c6347c3a87f4803a09192ee 520 SMART SM00382 286 479 5.8E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS09455 ef0d64454c6347c3a87f4803a09192ee 520 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS09455 ef0d64454c6347c3a87f4803a09192ee 520 Pfam PF00005 ABC transporter 277 431 4.8E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS09455 ef0d64454c6347c3a87f4803a09192ee 520 Gene3D G3DSA:1.10.3720.10 11 220 7.2E-40 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09455 ef0d64454c6347c3a87f4803a09192ee 520 SUPERFAMILY SSF52540 261 497 3.13E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10190 481470703d1ea1b2a82b5dd87c47ac36 397 Hamap MF_01857 Ribosomal RNA large subunit methyltransferase I [rlmI]. 1 397 69.212 T 22-04-2016 IPR023542 rRNA large subunit methyltransferase I GO:0008649 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS10190 481470703d1ea1b2a82b5dd87c47ac36 397 Gene3D G3DSA:3.30.750.80 73 180 7.1E-35 T 22-04-2016 TOLA_RS10190 481470703d1ea1b2a82b5dd87c47ac36 397 Gene3D G3DSA:3.40.50.150 184 395 4.4E-66 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS10190 481470703d1ea1b2a82b5dd87c47ac36 397 PANTHER PTHR11061 4 395 2.7E-121 T 22-04-2016 TOLA_RS10190 481470703d1ea1b2a82b5dd87c47ac36 397 SUPERFAMILY SSF88697 4 72 1.63E-17 T 22-04-2016 IPR015947 PUA-like domain TOLA_RS10190 481470703d1ea1b2a82b5dd87c47ac36 397 SMART SM00359 3 88 9.7E-16 T 22-04-2016 IPR002478 PUA domain GO:0003723 TOLA_RS10190 481470703d1ea1b2a82b5dd87c47ac36 397 Gene3D G3DSA:2.30.130.10 4 72 8.2E-28 T 22-04-2016 IPR015947 PUA-like domain TOLA_RS10190 481470703d1ea1b2a82b5dd87c47ac36 397 PANTHER PTHR11061:SF12 4 395 2.7E-121 T 22-04-2016 TOLA_RS10190 481470703d1ea1b2a82b5dd87c47ac36 397 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 115 352 5.5E-28 T 22-04-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 TOLA_RS10190 481470703d1ea1b2a82b5dd87c47ac36 397 SUPERFAMILY SSF53335 79 393 3.73E-75 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 ProSitePatterns PS00802 Transketolase signature 2. 469 485 - T 22-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 PANTHER PTHR11624 338 666 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 PANTHER PTHR11624 1 311 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 Gene3D G3DSA:3.40.50.970 6 321 2.1E-132 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 Pfam PF02779 Transketolase, pyrimidine binding domain 356 526 2.7E-46 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 TIGRFAM TIGR00232 tktlase_bact: transketolase 7 665 0.0 T 22-04-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 7 334 2.3E-165 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 ProSitePatterns PS00801 Transketolase signature 1. 13 33 - T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 SUPERFAMILY SSF52518 6 321 1.47E-120 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 Gene3D G3DSA:3.40.50.970 329 535 1.0E-77 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 SMART SM00861 356 528 8.1E-67 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 SUPERFAMILY SSF52518 337 527 3.1E-66 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 PANTHER PTHR11624:SF1 338 666 0.0 T 22-04-2016 TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 PANTHER PTHR11624:SF1 1 311 0.0 T 22-04-2016 TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 Pfam PF02780 Transketolase, C-terminal domain 542 657 1.3E-19 T 22-04-2016 IPR033248 Transketolase, C-terminal domain TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 SUPERFAMILY SSF52922 535 666 4.58E-40 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS09335 dd5a900d5c56635f5bf436c96932557b 666 Gene3D G3DSA:3.40.50.920 540 665 3.9E-46 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS01540 8c71adeed3bac8297217e6fa9ca436e3 464 Gene3D G3DSA:1.20.1600.10 345 457 5.0E-74 T 22-04-2016 TOLA_RS01540 8c71adeed3bac8297217e6fa9ca436e3 464 Gene3D G3DSA:1.20.1600.10 51 88 5.0E-74 T 22-04-2016 TOLA_RS01540 8c71adeed3bac8297217e6fa9ca436e3 464 Gene3D G3DSA:1.20.1600.10 138 309 5.0E-74 T 22-04-2016 TOLA_RS01540 8c71adeed3bac8297217e6fa9ca436e3 464 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 457 9.4E-78 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 TOLA_RS01540 8c71adeed3bac8297217e6fa9ca436e3 464 Gene3D G3DSA:2.20.200.10 310 342 1.6E-9 T 22-04-2016 TOLA_RS01540 8c71adeed3bac8297217e6fa9ca436e3 464 Gene3D G3DSA:2.20.200.10 99 137 1.6E-9 T 22-04-2016 TOLA_RS01540 8c71adeed3bac8297217e6fa9ca436e3 464 PANTHER PTHR30203:SF13 34 457 1.9E-95 T 22-04-2016 TOLA_RS01540 8c71adeed3bac8297217e6fa9ca436e3 464 SUPERFAMILY SSF56954 6 458 2.88E-82 T 22-04-2016 TOLA_RS01540 8c71adeed3bac8297217e6fa9ca436e3 464 Pfam PF02321 Outer membrane efflux protein 62 249 6.9E-19 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS01540 8c71adeed3bac8297217e6fa9ca436e3 464 Pfam PF02321 Outer membrane efflux protein 276 456 5.6E-18 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS01540 8c71adeed3bac8297217e6fa9ca436e3 464 PANTHER PTHR30203 34 457 1.9E-95 T 22-04-2016 TOLA_RS15820 3f4a52d72533dc5f594303498eaa831f 150 SUPERFAMILY SSF158682 10 147 1.7E-27 T 22-04-2016 IPR029024 TerB-like TOLA_RS15820 3f4a52d72533dc5f594303498eaa831f 150 Gene3D G3DSA:1.10.3680.10 14 143 1.3E-19 T 22-04-2016 IPR029024 TerB-like TOLA_RS15820 3f4a52d72533dc5f594303498eaa831f 150 Pfam PF05099 Tellurite resistance protein TerB 5 144 5.0E-37 T 22-04-2016 IPR007791 Co-chaperone DjlA, N-terminal TOLA_RS07340 2ab57beb2d9565544f7f83ae2c3bccdf 303 SUPERFAMILY SSF46785 1 83 1.04E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07340 2ab57beb2d9565544f7f83ae2c3bccdf 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.5E-18 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07340 2ab57beb2d9565544f7f83ae2c3bccdf 303 SUPERFAMILY SSF53850 89 293 1.3E-23 T 22-04-2016 TOLA_RS07340 2ab57beb2d9565544f7f83ae2c3bccdf 303 Gene3D G3DSA:3.40.190.10 188 252 6.2E-7 T 22-04-2016 TOLA_RS07340 2ab57beb2d9565544f7f83ae2c3bccdf 303 PANTHER PTHR30293:SF2 2 284 2.0E-60 T 22-04-2016 TOLA_RS07340 2ab57beb2d9565544f7f83ae2c3bccdf 303 PANTHER PTHR30293 2 284 2.0E-60 T 22-04-2016 TOLA_RS07340 2ab57beb2d9565544f7f83ae2c3bccdf 303 Pfam PF03466 LysR substrate binding domain 91 292 1.8E-13 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS07340 2ab57beb2d9565544f7f83ae2c3bccdf 303 Gene3D G3DSA:1.10.10.10 1 81 1.2E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15535 5fb4cff4b1cde567bf758f14c08dec10 487 Gene3D G3DSA:1.10.1040.10 276 483 6.7E-65 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TOLA_RS15535 5fb4cff4b1cde567bf758f14c08dec10 487 SUPERFAMILY SSF51735 3 257 1.34E-65 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS15535 5fb4cff4b1cde567bf758f14c08dec10 487 Gene3D G3DSA:3.40.50.720 3 253 3.9E-67 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS15535 5fb4cff4b1cde567bf758f14c08dec10 487 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 203 462 2.9E-63 T 22-04-2016 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 TOLA_RS15535 5fb4cff4b1cde567bf758f14c08dec10 487 PANTHER PTHR30524 2 487 2.1E-289 T 22-04-2016 TOLA_RS15535 5fb4cff4b1cde567bf758f14c08dec10 487 SUPERFAMILY SSF48179 277 483 2.86E-49 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS15535 5fb4cff4b1cde567bf758f14c08dec10 487 PANTHER PTHR30524:SF1 2 487 2.1E-289 T 22-04-2016 TOLA_RS15535 5fb4cff4b1cde567bf758f14c08dec10 487 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 17 172 1.4E-32 T 22-04-2016 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 1 402 48.644 T 22-04-2016 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 4 376 3.7E-149 T 22-04-2016 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 PANTHER PTHR22572 5 377 1.6E-154 T 22-04-2016 TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 10 29 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 95 103 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 Gene3D G3DSA:3.90.550.10 323 366 8.6E-71 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 Gene3D G3DSA:3.90.550.10 7 281 8.6E-71 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 193 203 - T 22-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 SUPERFAMILY SSF51161 293 401 1.83E-19 T 22-04-2016 IPR011004 Trimeric LpxA-like TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 PANTHER PTHR22572:SF10 5 377 1.6E-154 T 22-04-2016 TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 Pfam PF00483 Nucleotidyl transferase 6 270 1.8E-62 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 SUPERFAMILY SSF53448 340 356 3.52E-70 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS13365 d118ee290e6cd2cf48dbfe710fad1f9f 404 SUPERFAMILY SSF53448 5 274 3.52E-70 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 Gene3D G3DSA:3.30.70.270 345 506 9.5E-52 T 22-04-2016 TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 SUPERFAMILY SSF141868 516 760 6.28E-69 T 22-04-2016 IPR001633 EAL domain TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 Pfam PF00672 HAMP domain 267 333 5.3E-7 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 Pfam PF00563 EAL domain 517 748 6.3E-59 T 22-04-2016 IPR001633 EAL domain TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 SMART SM00267 332 501 3.8E-56 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 Pfam PF05228 CHASE4 domain 56 213 2.1E-30 T 22-04-2016 IPR007892 CHASE4 TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 SUPERFAMILY SSF55073 348 503 3.84E-46 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 PANTHER PTHR10799:SF710 1 115 5.5E-53 T 22-04-2016 TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 PANTHER PTHR10799:SF710 375 590 5.5E-53 T 22-04-2016 TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 PANTHER PTHR10799:SF710 612 631 5.5E-53 T 22-04-2016 TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 SMART SM00052 511 753 1.3E-74 T 22-04-2016 IPR001633 EAL domain TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 PANTHER PTHR10799 1 115 5.5E-53 T 22-04-2016 TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 PANTHER PTHR10799 375 590 5.5E-53 T 22-04-2016 TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 PANTHER PTHR10799 612 631 5.5E-53 T 22-04-2016 TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 Gene3D G3DSA:3.20.20.450 514 760 3.4E-73 T 22-04-2016 IPR001633 EAL domain TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 341 500 1.2E-37 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16275 d5762ef1f1d70b6edfea57f5157d5e74 764 Pfam PF00990 Diguanylate cyclase, GGDEF domain 344 496 1.3E-43 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS12910 9f875b758b02615d3be9314bb0a087ff 483 Gene3D G3DSA:3.40.50.300 247 461 1.1E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12910 9f875b758b02615d3be9314bb0a087ff 483 ProSitePatterns PS00211 ABC transporters family signature. 395 409 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS12910 9f875b758b02615d3be9314bb0a087ff 483 Pfam PF00005 ABC transporter 270 422 3.0E-22 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS12910 9f875b758b02615d3be9314bb0a087ff 483 Pfam PF00005 ABC transporter 20 159 1.5E-19 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS12910 9f875b758b02615d3be9314bb0a087ff 483 SMART SM00382 26 261 7.5E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS12910 9f875b758b02615d3be9314bb0a087ff 483 SMART SM00382 279 472 2.1E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS12910 9f875b758b02615d3be9314bb0a087ff 483 PANTHER PTHR24220:SF557 3 378 8.9E-113 T 22-04-2016 TOLA_RS12910 9f875b758b02615d3be9314bb0a087ff 483 PANTHER PTHR24220 3 378 8.9E-113 T 22-04-2016 TOLA_RS12910 9f875b758b02615d3be9314bb0a087ff 483 Gene3D G3DSA:3.40.50.300 3 228 1.8E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12910 9f875b758b02615d3be9314bb0a087ff 483 SUPERFAMILY SSF52540 246 465 3.01E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12910 9f875b758b02615d3be9314bb0a087ff 483 SUPERFAMILY SSF52540 2 227 3.93E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01895 ca94eae938b1c4a927277fdfb49199b8 395 SUPERFAMILY SSF53067 148 232 4.01E-19 T 22-04-2016 TOLA_RS01895 ca94eae938b1c4a927277fdfb49199b8 395 Pfam PF12693 GspL periplasmic domain 239 394 2.4E-41 T 22-04-2016 IPR025691 GspL periplasmic domain TOLA_RS01895 ca94eae938b1c4a927277fdfb49199b8 395 TIGRFAM TIGR01709 typeII_sec_gspL: type II secretion system protein L 5 393 5.0E-93 T 22-04-2016 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 TOLA_RS01895 ca94eae938b1c4a927277fdfb49199b8 395 PIRSF PIRSF015761 14 394 9.3E-39 T 22-04-2016 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 TOLA_RS01895 ca94eae938b1c4a927277fdfb49199b8 395 Pfam PF05134 Type II secretion system (T2SS), protein L 5 232 4.7E-63 T 22-04-2016 IPR024230 GspL, cytoplasmic actin-ATPase-like domain TOLA_RS01895 ca94eae938b1c4a927277fdfb49199b8 395 SUPERFAMILY SSF53067 3 144 1.18E-39 T 22-04-2016 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 Pfam PF13185 GAF domain 17 153 3.8E-13 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 Pfam PF05524 PEP-utilising enzyme, N-terminal 174 297 5.2E-26 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 PANTHER PTHR22931:SF23 183 722 9.7E-230 T 22-04-2016 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 PANTHER PTHR22931 183 722 9.7E-230 T 22-04-2016 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 SUPERFAMILY SSF51621 422 713 3.14E-94 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 SUPERFAMILY SSF47831 201 312 4.97E-26 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 SUPERFAMILY SSF55781 2 159 1.22E-28 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 Gene3D G3DSA:3.30.450.40 2 159 4.1E-45 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 Gene3D G3DSA:1.10.274.10 200 302 4.0E-31 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 423 712 6.8E-95 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 Gene3D G3DSA:3.50.30.10 303 418 4.7E-32 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 Pfam PF00391 PEP-utilising enzyme, mobile domain 322 394 1.0E-17 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 354 365 - T 22-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 Gene3D G3DSA:3.20.20.60 423 741 1.1E-97 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 SUPERFAMILY SSF52009 296 414 9.68E-28 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 174 736 1.0E-138 T 22-04-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 672 684 9.0E-24 T 22-04-2016 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 462 481 9.0E-24 T 22-04-2016 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 619 634 9.0E-24 T 22-04-2016 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 636 651 9.0E-24 T 22-04-2016 TOLA_RS15190 93990364dccfd017449c85532791c4cb 754 SMART SM00065 14 164 1.3E-19 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS00335 b65622c43c4b0a839b9191800b73bada 297 SUPERFAMILY SSF51730 22 295 2.75E-96 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like TOLA_RS00335 b65622c43c4b0a839b9191800b73bada 297 Gene3D G3DSA:3.20.20.220 12 295 3.3E-109 T 22-04-2016 IPR029041 FAD-linked oxidoreductase-like TOLA_RS00335 b65622c43c4b0a839b9191800b73bada 297 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 25 291 8.1E-102 T 22-04-2016 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 TOLA_RS00335 b65622c43c4b0a839b9191800b73bada 297 Pfam PF02219 Methylenetetrahydrofolate reductase 18 292 2.3E-107 T 22-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 TOLA_RS00335 b65622c43c4b0a839b9191800b73bada 297 PANTHER PTHR21091 149 280 1.3E-45 T 22-04-2016 TOLA_RS00335 b65622c43c4b0a839b9191800b73bada 297 PANTHER PTHR21091:SF31 149 280 1.3E-45 T 22-04-2016 TOLA_RS10720 8aeee959e714e7784281affe0244cfcf 185 Gene3D G3DSA:1.10.132.20 67 185 8.2E-45 T 22-04-2016 IPR023584 Ribosome recycling factor domain TOLA_RS10720 8aeee959e714e7784281affe0244cfcf 185 PANTHER PTHR20982 1 185 9.7E-82 T 22-04-2016 IPR002661 Ribosome recycling factor GO:0006412 TOLA_RS10720 8aeee959e714e7784281affe0244cfcf 185 Pfam PF01765 Ribosome recycling factor 20 183 2.2E-63 T 22-04-2016 IPR023584 Ribosome recycling factor domain TOLA_RS10720 8aeee959e714e7784281affe0244cfcf 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 3.1E-75 T 22-04-2016 IPR002661 Ribosome recycling factor GO:0006412 TOLA_RS10720 8aeee959e714e7784281affe0244cfcf 185 SUPERFAMILY SSF55194 2 184 1.16E-70 T 22-04-2016 IPR023584 Ribosome recycling factor domain TOLA_RS10720 8aeee959e714e7784281affe0244cfcf 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.413 T 22-04-2016 IPR002661 Ribosome recycling factor GO:0006412 TOLA_RS13580 4991378ad517a1419a662329cf96b5c1 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 20.81 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 TOLA_RS13580 4991378ad517a1419a662329cf96b5c1 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 56 3.0E-14 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 TOLA_RS13580 4991378ad517a1419a662329cf96b5c1 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 22-04-2016 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS13580 4991378ad517a1419a662329cf96b5c1 71 PANTHER PTHR21109 1 71 1.3E-25 T 22-04-2016 TOLA_RS13580 4991378ad517a1419a662329cf96b5c1 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 3.8E-24 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 TOLA_RS13580 4991378ad517a1419a662329cf96b5c1 71 Pfam PF01165 Ribosomal protein S21 4 56 1.6E-21 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 TOLA_RS13580 4991378ad517a1419a662329cf96b5c1 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 4.9E-16 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 TOLA_RS13580 4991378ad517a1419a662329cf96b5c1 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 4.9E-16 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 TOLA_RS13580 4991378ad517a1419a662329cf96b5c1 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 4.9E-16 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 TOLA_RS13580 4991378ad517a1419a662329cf96b5c1 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 4.9E-16 T 22-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 SUPERFAMILY SSF53067 8 201 1.68E-62 T 22-04-2016 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 Gene3D G3DSA:3.30.420.40 95 209 9.1E-10 T 22-04-2016 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 TIGRFAM TIGR00016 ackA: acetate kinase 8 400 6.1E-150 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 PIRSF PIRSF000722 5 402 5.1E-140 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 PANTHER PTHR21060 5 399 1.6E-218 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 Pfam PF00871 Acetokinase family 9 395 4.5E-153 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 PANTHER PTHR21060:SF15 5 399 1.6E-218 T 22-04-2016 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 Hamap MF_00020 Acetate kinase [ackA]. 1 402 174.908 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 208 225 - T 22-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 PRINTS PR00471 Acetate kinase family signature 305 318 1.9E-45 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 PRINTS PR00471 Acetate kinase family signature 327 343 1.9E-45 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 PRINTS PR00471 Acetate kinase family signature 382 394 1.9E-45 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 PRINTS PR00471 Acetate kinase family signature 9 20 1.9E-45 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 PRINTS PR00471 Acetate kinase family signature 178 191 1.9E-45 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 PRINTS PR00471 Acetate kinase family signature 208 229 1.9E-45 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 9 20 - T 22-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 SUPERFAMILY SSF53067 163 399 1.3E-84 T 22-04-2016 TOLA_RS06985 5b2c34ca1925f325c1f6c6dc8a013f43 402 Gene3D G3DSA:3.30.420.40 210 399 5.0E-74 T 22-04-2016 TOLA_RS04400 82f0ee200de96d533b30f5e18bdb2bbf 143 PANTHER PTHR33202 1 135 7.3E-45 T 22-04-2016 TOLA_RS04400 82f0ee200de96d533b30f5e18bdb2bbf 143 Pfam PF01475 Ferric uptake regulator family 11 130 4.6E-47 T 22-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TOLA_RS04400 82f0ee200de96d533b30f5e18bdb2bbf 143 Gene3D G3DSA:1.10.10.10 3 82 7.4E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS04400 82f0ee200de96d533b30f5e18bdb2bbf 143 SUPERFAMILY SSF46785 4 134 1.67E-43 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 Gene3D G3DSA:1.10.8.60 193 264 4.3E-21 T 22-04-2016 TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 SUPERFAMILY SSF52540 20 262 4.31E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 106 121 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 SMART SM00382 40 183 2.6E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 Gene3D G3DSA:3.40.50.300 19 192 2.8E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 Gene3D G3DSA:1.10.10.60 273 328 2.5E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 PANTHER PTHR32071 8 333 2.8E-141 T 22-04-2016 TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 Pfam PF02954 Bacterial regulatory protein, Fis family 289 325 3.7E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 44 57 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 SUPERFAMILY SSF46689 234 328 4.48E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 Pfam PF00158 Sigma-54 interaction domain 20 186 6.3E-69 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 291 308 1.9E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS01080 874b4ad391242629cbc4c1dcaf905b09 334 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 308 328 1.9E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS00320 6091c2080946dcb8cd9dc1330e1ad31c 1130 Gene3D G3DSA:3.40.50.300 649 745 2.3E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00320 6091c2080946dcb8cd9dc1330e1ad31c 1130 Gene3D G3DSA:3.40.50.300 352 444 2.3E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00320 6091c2080946dcb8cd9dc1330e1ad31c 1130 PANTHER PTHR30591 1 1129 2.8E-269 T 22-04-2016 TOLA_RS00320 6091c2080946dcb8cd9dc1330e1ad31c 1130 SUPERFAMILY SSF52980 821 1125 5.36E-69 T 22-04-2016 IPR011335 Restriction endonuclease type II-like TOLA_RS00320 6091c2080946dcb8cd9dc1330e1ad31c 1130 Gene3D G3DSA:1.10.10.160 87 178 3.7E-32 T 22-04-2016 IPR013986 DExx box DNA helicase domain TOLA_RS00320 6091c2080946dcb8cd9dc1330e1ad31c 1130 PANTHER PTHR30591:SF1 1 1129 2.8E-269 T 22-04-2016 TOLA_RS00320 6091c2080946dcb8cd9dc1330e1ad31c 1130 SUPERFAMILY SSF52540 1 346 2.02E-110 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00320 6091c2080946dcb8cd9dc1330e1ad31c 1130 PIRSF PIRSF000980 1 1130 0.0 T 22-04-2016 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 TOLA_RS00320 6091c2080946dcb8cd9dc1330e1ad31c 1130 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 1 804 3.3E-288 T 22-04-2016 TOLA_RS00320 6091c2080946dcb8cd9dc1330e1ad31c 1130 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 1 1127 13.359 T 22-04-2016 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 TOLA_RS00320 6091c2080946dcb8cd9dc1330e1ad31c 1130 SUPERFAMILY SSF52540 350 808 1.81E-95 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00320 6091c2080946dcb8cd9dc1330e1ad31c 1130 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 2 1091 0.0 T 22-04-2016 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 TOLA_RS14870 7dce46fb9b0aaaf85cc09df9c24f61f6 276 PANTHER PTHR30151 42 276 2.6E-39 T 22-04-2016 TOLA_RS14870 7dce46fb9b0aaaf85cc09df9c24f61f6 276 SUPERFAMILY SSF161098 71 257 3.01E-27 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS14870 7dce46fb9b0aaaf85cc09df9c24f61f6 276 PANTHER PTHR30151:SF0 42 276 2.6E-39 T 22-04-2016 TOLA_RS14870 7dce46fb9b0aaaf85cc09df9c24f61f6 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 262 9.3E-17 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS14870 7dce46fb9b0aaaf85cc09df9c24f61f6 276 Gene3D G3DSA:1.10.3720.10 70 262 1.9E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00745 14921f6b59c588326e5ebe877394db85 173 Pfam PF04345 Chorismate lyase 11 167 9.0E-17 T 22-04-2016 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|UniPathway: UPA00232 TOLA_RS00745 14921f6b59c588326e5ebe877394db85 173 PANTHER PTHR38683 1 171 1.2E-13 T 22-04-2016 TOLA_RS00745 14921f6b59c588326e5ebe877394db85 173 Gene3D G3DSA:3.40.1410.10 10 171 3.6E-31 T 22-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain TOLA_RS00745 14921f6b59c588326e5ebe877394db85 173 SUPERFAMILY SSF64288 11 171 2.51E-26 T 22-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 SUPERFAMILY SSF48557 1 458 3.68E-142 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 PRINTS PR00145 Argininosuccinate lyase family signature 178 198 4.5E-5 T 22-04-2016 TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 PRINTS PR00145 Argininosuccinate lyase family signature 137 159 4.5E-5 T 22-04-2016 TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 PRINTS PR00145 Argininosuccinate lyase family signature 320 336 4.5E-5 T 22-04-2016 TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 Gene3D G3DSA:1.20.200.10 143 405 3.5E-89 T 22-04-2016 TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 Pfam PF10415 Fumarase C C-terminus 411 462 3.4E-18 T 22-04-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 Pfam PF00206 Lyase 13 345 3.9E-101 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 ProSitePatterns PS00163 Fumarate lyases signature. 320 329 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 PANTHER PTHR11444:SF25 1 466 4.7E-264 T 22-04-2016 TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 6 471 1.8E-228 T 22-04-2016 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 PRINTS PR00149 Fumarate lyase superfamily signature 274 301 5.9E-27 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 PRINTS PR00149 Fumarate lyase superfamily signature 138 156 5.9E-27 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 PRINTS PR00149 Fumarate lyase superfamily signature 183 201 5.9E-27 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 PRINTS PR00149 Fumarate lyase superfamily signature 320 336 5.9E-27 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 Gene3D G3DSA:1.10.275.10 4 142 3.6E-50 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 Gene3D G3DSA:1.10.40.30 411 461 6.3E-19 T 22-04-2016 TOLA_RS15435 709be9c84267097599343ae8197e7a46 473 PANTHER PTHR11444 1 466 4.7E-264 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS03115 e2d6b42c1421c299b3233c8dc8021025 469 PANTHER PTHR11228 34 411 4.7E-100 T 22-04-2016 TOLA_RS03115 e2d6b42c1421c299b3233c8dc8021025 469 Gene3D G3DSA:3.30.420.130 340 453 8.2E-32 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS03115 e2d6b42c1421c299b3233c8dc8021025 469 SUPERFAMILY SSF102114 39 269 8.11E-35 T 22-04-2016 TOLA_RS03115 e2d6b42c1421c299b3233c8dc8021025 469 Pfam PF04055 Radical SAM superfamily 52 230 1.8E-21 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS03115 e2d6b42c1421c299b3233c8dc8021025 469 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 353 451 5.4E-20 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS03115 e2d6b42c1421c299b3233c8dc8021025 469 SUPERFAMILY SSF53146 342 455 1.31E-28 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS03115 e2d6b42c1421c299b3233c8dc8021025 469 PANTHER PTHR11228:SF18 34 411 4.7E-100 T 22-04-2016 TOLA_RS03115 e2d6b42c1421c299b3233c8dc8021025 469 Gene3D G3DSA:3.20.20.70 42 308 1.7E-40 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS03115 e2d6b42c1421c299b3233c8dc8021025 469 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 52 63 - T 22-04-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS03115 e2d6b42c1421c299b3233c8dc8021025 469 TIGRFAM TIGR01290 nifB: nitrogenase cofactor biosynthesis protein NifB 27 449 9.9E-194 T 22-04-2016 IPR005980 Nitrogenase cofactor biosynthesis protein NifB GO:0009108|GO:0009399 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 PANTHER PTHR22931 172 664 1.5E-298 T 22-04-2016 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 Gene3D G3DSA:1.10.274.10 157 245 8.9E-17 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 614 626 5.3E-22 T 22-04-2016 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 561 576 5.3E-22 T 22-04-2016 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 407 426 5.3E-22 T 22-04-2016 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 578 593 5.3E-22 T 22-04-2016 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 SUPERFAMILY SSF55804 690 831 4.58E-32 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 Pfam PF00391 PEP-utilising enzyme, mobile domain 267 339 1.2E-15 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 SUPERFAMILY SSF52009 238 358 6.41E-23 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 Gene3D G3DSA:3.40.930.10 690 831 6.0E-41 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 14 21 - T 22-04-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 Gene3D G3DSA:3.30.1340.10 4 88 5.2E-19 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 Pfam PF05524 PEP-utilising enzyme, N-terminal 121 239 3.1E-15 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 365 655 4.5E-113 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 SUPERFAMILY SSF51621 367 662 3.66E-99 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 PRINTS PR00107 Phosphocarrier protein signature 41 56 7.7E-5 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 PRINTS PR00107 Phosphocarrier protein signature 14 30 7.7E-5 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 PRINTS PR00107 Phosphocarrier protein signature 56 73 7.7E-5 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 298 309 - T 22-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 121 679 9.7E-156 T 22-04-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 SUPERFAMILY SSF55594 5 89 3.01E-16 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 PANTHER PTHR22931:SF24 172 664 1.5E-298 T 22-04-2016 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 Pfam PF00381 PTS HPr component phosphorylation site 6 85 7.9E-13 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 Gene3D G3DSA:3.50.30.10 246 366 2.0E-27 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 691 830 2.7E-33 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 SUPERFAMILY SSF47831 148 256 3.01E-17 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 561 579 - T 22-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TOLA_RS09690 aab11e6d473b45ef1b1249dfbd6e8534 835 Gene3D G3DSA:3.20.20.60 367 682 1.1E-104 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS08430 5840fc103ae2768970e4df0f7e1072ca 274 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 105 1.9E-20 T 22-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 TOLA_RS08430 5840fc103ae2768970e4df0f7e1072ca 274 Gene3D G3DSA:3.90.1170.20 5 126 4.2E-28 T 22-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 TOLA_RS08430 5840fc103ae2768970e4df0f7e1072ca 274 SUPERFAMILY SSF51690 107 270 1.61E-37 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 TOLA_RS08430 5840fc103ae2768970e4df0f7e1072ca 274 SUPERFAMILY SSF54675 4 106 3.06E-20 T 22-04-2016 TOLA_RS08430 5840fc103ae2768970e4df0f7e1072ca 274 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 107 270 3.7E-29 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 TOLA_RS08430 5840fc103ae2768970e4df0f7e1072ca 274 PANTHER PTHR11948 1 266 1.6E-39 T 22-04-2016 TOLA_RS08430 5840fc103ae2768970e4df0f7e1072ca 274 PIRSF PIRSF006250 3 274 1.5E-56 T 22-04-2016 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD TOLA_RS08430 5840fc103ae2768970e4df0f7e1072ca 274 Gene3D G3DSA:3.20.20.70 127 263 1.7E-35 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS08430 5840fc103ae2768970e4df0f7e1072ca 274 TIGRFAM TIGR01334 modD: modD protein 5 272 2.3E-75 T 22-04-2016 IPR006242 Putative pyrophosphorylase ModD GO:0016763 KEGG: 00230+2.4.2.-|KEGG: 00514+2.4.2.- TOLA_RS08430 5840fc103ae2768970e4df0f7e1072ca 274 PANTHER PTHR11948:SF1 1 266 1.6E-39 T 22-04-2016 TOLA_RS13785 489954a51c64e4648816dc9d4942590a 262 Pfam PF16331 TolA binding protein trimerisation 27 99 7.0E-24 T 22-04-2016 IPR032519 YbgF, trimerisation domain GO:0070206 TOLA_RS13785 489954a51c64e4648816dc9d4942590a 262 Pfam PF13174 Tetratricopeptide repeat 156 176 0.049 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS13785 489954a51c64e4648816dc9d4942590a 262 Gene3D G3DSA:1.25.40.10 139 254 2.7E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS13785 489954a51c64e4648816dc9d4942590a 262 PANTHER PTHR26312:SF74 154 260 1.4E-24 T 22-04-2016 TOLA_RS13785 489954a51c64e4648816dc9d4942590a 262 SUPERFAMILY SSF48452 151 255 2.96E-14 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS13785 489954a51c64e4648816dc9d4942590a 262 SMART SM00028 217 250 4.4 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS13785 489954a51c64e4648816dc9d4942590a 262 SMART SM00028 180 213 48.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS13785 489954a51c64e4648816dc9d4942590a 262 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 144 260 3.4E-39 T 22-04-2016 IPR014162 Tol-Pal system, YbgF TOLA_RS13785 489954a51c64e4648816dc9d4942590a 262 Pfam PF13432 Tetratricopeptide repeat 186 249 1.1E-6 T 22-04-2016 TOLA_RS13785 489954a51c64e4648816dc9d4942590a 262 PANTHER PTHR26312 154 260 1.4E-24 T 22-04-2016 TOLA_RS10625 79f047a2a0860c89ffeac4d28090e0d9 197 PANTHER PTHR12608 1 189 1.7E-33 T 22-04-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 TOLA_RS10625 79f047a2a0860c89ffeac4d28090e0d9 197 Pfam PF01169 Uncharacterized protein family UPF0016 7 80 2.4E-17 T 22-04-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 TOLA_RS10625 79f047a2a0860c89ffeac4d28090e0d9 197 Pfam PF01169 Uncharacterized protein family UPF0016 104 178 4.3E-23 T 22-04-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 TOLA_RS13465 f4d746073b5b2e0a1d7aebdad3ea2b60 322 PANTHER PTHR11432 1 322 9.0E-229 T 22-04-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 TOLA_RS13465 f4d746073b5b2e0a1d7aebdad3ea2b60 322 Pfam PF00146 NADH dehydrogenase 15 313 3.8E-121 T 22-04-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 TOLA_RS13465 f4d746073b5b2e0a1d7aebdad3ea2b60 322 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 7 320 24.032 T 22-04-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 TOLA_RS13465 f4d746073b5b2e0a1d7aebdad3ea2b60 322 PANTHER PTHR11432:SF8 1 322 9.0E-229 T 22-04-2016 TOLA_RS13465 f4d746073b5b2e0a1d7aebdad3ea2b60 322 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 208 221 - T 22-04-2016 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 TOLA_RS13465 f4d746073b5b2e0a1d7aebdad3ea2b60 322 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 53 68 - T 22-04-2016 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 TOLA_RS08845 c6afcafe2af7a5827a289d21a1735042 245 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 2 238 2.3E-76 T 22-04-2016 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 TOLA_RS08845 c6afcafe2af7a5827a289d21a1735042 245 Pfam PF00977 Histidine biosynthesis protein 1 234 3.4E-74 T 22-04-2016 IPR006062 Histidine biosynthesis GO:0000105 TOLA_RS08845 c6afcafe2af7a5827a289d21a1735042 245 SUPERFAMILY SSF51366 1 242 1.82E-63 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TOLA_RS08845 c6afcafe2af7a5827a289d21a1735042 245 PANTHER PTHR21235 1 243 3.0E-106 T 22-04-2016 TOLA_RS08845 c6afcafe2af7a5827a289d21a1735042 245 PANTHER PTHR21235:SF15 1 243 3.0E-106 T 22-04-2016 TOLA_RS08845 c6afcafe2af7a5827a289d21a1735042 245 Gene3D G3DSA:3.20.20.70 1 243 5.2E-76 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS08845 c6afcafe2af7a5827a289d21a1735042 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 1 241 35.146 T 22-04-2016 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 SUPERFAMILY SSF56712 3 611 4.19E-198 T 22-04-2016 IPR023405 DNA topoisomerase, type IA, core domain TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 313 327 - T 22-04-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 SUPERFAMILY SSF57783 810 863 8.67E-22 T 22-04-2016 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 SMART SM00437 276 531 3.3E-117 T 22-04-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Gene3D G3DSA:2.70.20.10 342 477 5.1E-31 T 22-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Gene3D G3DSA:2.70.20.10 217 336 1.8E-30 T 22-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 318 327 7.4E-37 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 195 213 7.4E-37 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 394 410 7.4E-37 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 494 508 7.4E-37 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 110 123 7.4E-37 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Gene3D G3DSA:3.40.50.140 1 167 6.2E-54 T 22-04-2016 IPR006171 Toprim domain TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 599 624 8.2E-6 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 709 746 4.4E-11 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 PANTHER PTHR11390 71 777 0.0 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 PANTHER PTHR11390 1 37 0.0 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 SUPERFAMILY SSF57783 745 808 1.87E-18 T 22-04-2016 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 SUPERFAMILY SSF57783 584 624 1.24E-7 T 22-04-2016 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Pfam PF08272 Topoisomerase I zinc-ribbon-like 759 794 1.0E-12 T 22-04-2016 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Pfam PF08272 Topoisomerase I zinc-ribbon-like 825 863 1.5E-21 T 22-04-2016 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 724 54.034 T 22-04-2016 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 SMART SM00493 3 136 2.9E-26 T 22-04-2016 IPR006171 Toprim domain TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Pfam PF01751 Toprim domain 5 146 8.7E-31 T 22-04-2016 IPR006171 Toprim domain TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Gene3D G3DSA:2.20.25.10 810 864 9.3E-30 T 22-04-2016 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Pfam PF01131 DNA topoisomerase 162 567 2.8E-124 T 22-04-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 PANTHER PTHR11390:SF27 71 777 0.0 T 22-04-2016 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 PANTHER PTHR11390:SF27 1 37 0.0 T 22-04-2016 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 SUPERFAMILY SSF57783 701 744 1.67E-7 T 22-04-2016 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 637 1.0E-248 T 22-04-2016 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 SMART SM00436 137 225 4.1E-48 T 22-04-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Gene3D G3DSA:1.10.460.10 168 215 9.8E-59 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Gene3D G3DSA:1.10.460.10 478 595 9.8E-59 T 22-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Gene3D G3DSA:3.30.65.10 596 631 1.5E-12 T 22-04-2016 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Gene3D G3DSA:3.30.65.10 708 744 4.7E-12 T 22-04-2016 TOLA_RS07060 33284e2d1db441fe4e803a453354f752 869 Gene3D G3DSA:3.30.65.10 745 807 1.3E-24 T 22-04-2016 TOLA_RS01620 140d62ab242bb0f918f77f3fd7ab8d5a 93 PANTHER PTHR37478:SF1 1 89 5.4E-27 T 22-04-2016 TOLA_RS01620 140d62ab242bb0f918f77f3fd7ab8d5a 93 Hamap MF_00674 UPF0251 protein . 2 93 22.856 T 22-04-2016 IPR002852 Uncharacterised protein family UPF0251 TOLA_RS01620 140d62ab242bb0f918f77f3fd7ab8d5a 93 Gene3D G3DSA:1.10.10.10 34 81 1.2E-4 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01620 140d62ab242bb0f918f77f3fd7ab8d5a 93 PANTHER PTHR37478 1 89 5.4E-27 T 22-04-2016 TOLA_RS01620 140d62ab242bb0f918f77f3fd7ab8d5a 93 SUPERFAMILY SSF88659 34 81 6.11E-5 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS01620 140d62ab242bb0f918f77f3fd7ab8d5a 93 Pfam PF02001 Protein of unknown function DUF134 2 90 1.8E-22 T 22-04-2016 IPR002852 Uncharacterised protein family UPF0251 TOLA_RS09570 2a1be6b7145307a639c66a7c4f65db2f 144 PANTHER PTHR34873:SF2 7 143 4.3E-22 T 22-04-2016 TOLA_RS09570 2a1be6b7145307a639c66a7c4f65db2f 144 PANTHER PTHR34873 7 143 4.3E-22 T 22-04-2016 TOLA_RS09570 2a1be6b7145307a639c66a7c4f65db2f 144 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 12 137 6.8E-24 T 22-04-2016 IPR031807 HicB-like antitoxin of toxin-antitoxin system TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 273 2.0E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 273 289 2.0E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 PANTHER PTHR11019:SF123 111 152 2.8E-46 T 22-04-2016 TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 PANTHER PTHR11019:SF123 173 297 2.8E-46 T 22-04-2016 TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 PANTHER PTHR11019 111 152 2.8E-46 T 22-04-2016 TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 PANTHER PTHR11019 173 297 2.8E-46 T 22-04-2016 TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 SMART SM00342 206 289 6.1E-34 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 Pfam PF12833 Helix-turn-helix domain 213 290 2.9E-20 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 Gene3D G3DSA:1.10.10.60 243 290 6.4E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 SUPERFAMILY SSF46689 189 240 5.38E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 Pfam PF10114 Sensory domain found in PocR 7 164 2.1E-43 T 22-04-2016 IPR018771 PocR domain UniPathway: UPA00148|UniPathway: UPA00621 TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 SUPERFAMILY SSF46689 243 291 1.43E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS08555 22f1dd68456e34cc3428a8b19c2a5e2f 299 Gene3D G3DSA:1.10.10.60 187 242 1.9E-19 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS00095 b23190bca9ec815e9bb98260c74c44c4 417 Pfam PF01547 Bacterial extracellular solute-binding protein 59 289 4.3E-19 T 22-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 TOLA_RS00095 b23190bca9ec815e9bb98260c74c44c4 417 Gene3D G3DSA:3.40.190.10 143 332 1.5E-25 T 22-04-2016 TOLA_RS00095 b23190bca9ec815e9bb98260c74c44c4 417 PANTHER PTHR30061:SF22 19 417 2.6E-85 T 22-04-2016 TOLA_RS00095 b23190bca9ec815e9bb98260c74c44c4 417 PANTHER PTHR30061 19 417 2.6E-85 T 22-04-2016 TOLA_RS00095 b23190bca9ec815e9bb98260c74c44c4 417 SUPERFAMILY SSF53850 25 411 5.24E-49 T 22-04-2016 TOLA_RS13900 80d5d171619f0fb640a5df9cbb5faba8 338 PIRSF PIRSF006621 10 334 2.2E-73 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TOLA_RS13900 80d5d171619f0fb640a5df9cbb5faba8 338 SUPERFAMILY SSF51395 17 314 1.1E-73 T 22-04-2016 TOLA_RS13900 80d5d171619f0fb640a5df9cbb5faba8 338 Gene3D G3DSA:3.20.20.70 17 260 4.0E-76 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS13900 80d5d171619f0fb640a5df9cbb5faba8 338 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 9 333 52.947 T 22-04-2016 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 TOLA_RS13900 80d5d171619f0fb640a5df9cbb5faba8 338 Pfam PF01207 Dihydrouridine synthase (Dus) 21 323 6.9E-94 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TOLA_RS13900 80d5d171619f0fb640a5df9cbb5faba8 338 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 17 332 8.7E-163 T 22-04-2016 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 TOLA_RS13900 80d5d171619f0fb640a5df9cbb5faba8 338 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 99 117 - T 22-04-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 TOLA_RS13900 80d5d171619f0fb640a5df9cbb5faba8 338 PANTHER PTHR11082 12 318 1.2E-157 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TOLA_RS13900 80d5d171619f0fb640a5df9cbb5faba8 338 PANTHER PTHR11082:SF29 12 318 1.2E-157 T 22-04-2016 TOLA_RS13470 5f95f49bdc910bba31d9df3d095d9200 162 Gene3D G3DSA:3.30.70.20 15 99 4.2E-17 T 22-04-2016 TOLA_RS13470 5f95f49bdc910bba31d9df3d095d9200 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 1 119 4.7E-49 T 22-04-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 TOLA_RS13470 5f95f49bdc910bba31d9df3d095d9200 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 42 53 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS13470 5f95f49bdc910bba31d9df3d095d9200 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 81 92 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS13470 5f95f49bdc910bba31d9df3d095d9200 162 PANTHER PTHR10849:SF13 1 162 3.5E-75 T 22-04-2016 TOLA_RS13470 5f95f49bdc910bba31d9df3d095d9200 162 Pfam PF12838 4Fe-4S dicluster domain 41 95 1.1E-11 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TOLA_RS13470 5f95f49bdc910bba31d9df3d095d9200 162 SUPERFAMILY SSF54862 15 133 3.52E-28 T 22-04-2016 TOLA_RS13470 5f95f49bdc910bba31d9df3d095d9200 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 134 24.528 T 22-04-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 TOLA_RS13470 5f95f49bdc910bba31d9df3d095d9200 162 PANTHER PTHR10849 1 162 3.5E-75 T 22-04-2016 TOLA_RS03065 0ecdeb081b7cca26984dd40f003a6e4d 325 Pfam PF13533 Biotin-lipoyl like 50 97 1.1E-5 T 22-04-2016 TOLA_RS03065 0ecdeb081b7cca26984dd40f003a6e4d 325 Pfam PF13437 HlyD family secretion protein 187 289 5.6E-12 T 22-04-2016 TOLA_RS03065 0ecdeb081b7cca26984dd40f003a6e4d 325 Gene3D G3DSA:2.40.50.100 49 82 1.7E-10 T 22-04-2016 TOLA_RS03065 0ecdeb081b7cca26984dd40f003a6e4d 325 Gene3D G3DSA:2.40.50.100 185 217 1.7E-10 T 22-04-2016 TOLA_RS03065 0ecdeb081b7cca26984dd40f003a6e4d 325 SUPERFAMILY SSF111369 43 237 3.14E-12 T 22-04-2016 TOLA_RS03065 0ecdeb081b7cca26984dd40f003a6e4d 325 PANTHER PTHR30438:SF1 1 325 1.6E-61 T 22-04-2016 TOLA_RS03065 0ecdeb081b7cca26984dd40f003a6e4d 325 PANTHER PTHR30438 1 325 1.6E-61 T 22-04-2016 TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 PANTHER PTHR10099 1 1296 0.0 T 22-04-2016 TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 SUPERFAMILY SSF56042 431 614 1.15E-52 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 PANTHER PTHR10099:SF5 1 1296 0.0 T 22-04-2016 TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 Pfam PF02769 AIR synthase related protein, C-terminal domain 431 588 8.6E-28 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 Pfam PF02769 AIR synthase related protein, C-terminal domain 836 963 3.6E-13 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 SUPERFAMILY SSF56042 825 1033 2.09E-50 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1296 21.368 T 22-04-2016 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 SUPERFAMILY SSF52317 1037 1294 9.93E-98 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 SUPERFAMILY SSF55326 220 427 1.01E-65 T 22-04-2016 TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 3 1294 0.0 T 22-04-2016 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1041 1294 3.6E-108 T 22-04-2016 TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 SUPERFAMILY SSF55326 617 815 1.41E-66 T 22-04-2016 TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 SUPERFAMILY SSF109736 154 219 7.45E-22 T 22-04-2016 TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 SMART SM01211 1040 1295 9.4E-158 T 22-04-2016 TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 Gene3D G3DSA:3.40.50.880 1041 1268 5.5E-15 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 Gene3D G3DSA:3.30.1330.10 210 420 2.8E-39 T 22-04-2016 IPR016188 PurM-like, N-terminal domain TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 Gene3D G3DSA:3.30.1330.10 644 809 1.6E-14 T 22-04-2016 IPR016188 PurM-like, N-terminal domain TOLA_RS03265 0f778f2f09a4613508549ea01da6d8e7 1296 SUPERFAMILY SSF82697 1 151 2.62E-51 T 22-04-2016 TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 Gene3D G3DSA:1.10.1060.10 361 445 2.8E-17 T 22-04-2016 TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 SUPERFAMILY SSF46548 335 442 1.48E-20 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 PANTHER PTHR11780:SF1 1 482 1.2E-210 T 22-04-2016 TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 140 283 2.6E-44 T 22-04-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 SUPERFAMILY SSF142019 96 302 1.22E-55 T 22-04-2016 TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 Pfam PF10531 SLBB domain 296 344 4.4E-8 T 22-04-2016 IPR019554 Soluble ligand binding domain TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 Gene3D G3DSA:2.40.50.100 46 94 4.1E-4 T 22-04-2016 TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 Hamap MF_00461 Electron transport complex subunit RsxC [rsxC]. 1 702 217.898 T 22-04-2016 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 Pfam PF13375 RnfC Barrel sandwich hybrid domain 14 115 1.4E-29 T 22-04-2016 IPR026902 RnfC Barrel sandwich hybrid domain TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 Pfam PF13237 4Fe-4S dicluster domain 373 427 6.9E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 416 427 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 PANTHER PTHR11780 1 482 1.2E-210 T 22-04-2016 TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 13 445 5.6E-172 T 22-04-2016 IPR010208 Electron transport complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 TOLA_RS07385 126d2bcdb08b83add5b655afe7cd4c27 702 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 377 388 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS12410 a913baabacee4c04f51aac3702eae6ad 132 TIGRFAM TIGR03750 conj_TIGR03750: conjugative transfer region protein, TIGR03750 family 14 129 6.0E-42 T 22-04-2016 IPR021877 Protein of unknown function DUF3487 TOLA_RS12410 a913baabacee4c04f51aac3702eae6ad 132 Pfam PF11990 Protein of unknown function (DUF3487) 12 129 6.9E-41 T 22-04-2016 IPR021877 Protein of unknown function DUF3487 TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 Pfam PF08463 EcoEI R protein C-terminal 961 1105 9.7E-13 T 22-04-2016 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 PANTHER PTHR30195 72 1120 4.2E-167 T 22-04-2016 TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 Pfam PF04851 Type III restriction enzyme, res subunit 352 499 5.2E-33 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 146 311 1.9E-8 T 22-04-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 PANTHER PTHR30195:SF3 72 1120 4.2E-167 T 22-04-2016 TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 Pfam PF00271 Helicase conserved C-terminal domain 613 712 5.3E-8 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 Gene3D G3DSA:3.40.50.300 351 510 2.8E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 SMART SM00487 347 527 3.0E-14 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 SUPERFAMILY SSF52540 314 519 1.57E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 Gene3D G3DSA:3.40.50.300 596 713 1.5E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 SUPERFAMILY SSF52540 464 499 1.4E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 SUPERFAMILY SSF52540 585 715 1.4E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05910 095f4c4f68d03b16a15805c3b2c256ab 1123 Pfam PF13643 Domain of unknown function (DUF4145) 24 102 1.1E-4 T 22-04-2016 IPR025285 Domain of unknown function DUF4145 TOLA_RS05535 1485c345cfc602f7b9566ab95ab706c7 225 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 11 223 2.0E-90 T 22-04-2016 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 UniPathway: UPA00219 TOLA_RS05535 1485c345cfc602f7b9566ab95ab706c7 225 Pfam PF00912 Transglycosylase 52 218 1.6E-57 T 22-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 TOLA_RS05535 1485c345cfc602f7b9566ab95ab706c7 225 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 1 224 36.911 T 22-04-2016 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 UniPathway: UPA00219 TOLA_RS05535 1485c345cfc602f7b9566ab95ab706c7 225 Gene3D G3DSA:1.10.3810.10 51 222 8.7E-68 T 22-04-2016 TOLA_RS05535 1485c345cfc602f7b9566ab95ab706c7 225 PANTHER PTHR30400 5 223 1.4E-72 T 22-04-2016 TOLA_RS05535 1485c345cfc602f7b9566ab95ab706c7 225 PANTHER PTHR30400:SF0 5 223 1.4E-72 T 22-04-2016 TOLA_RS05535 1485c345cfc602f7b9566ab95ab706c7 225 SUPERFAMILY SSF53955 52 222 6.75E-59 T 22-04-2016 IPR023346 Lysozyme-like domain TOLA_RS14960 39d7e67073b946aba3a4d97de1d88fc7 280 Gene3D G3DSA:2.60.120.10 4 254 2.9E-83 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS14960 39d7e67073b946aba3a4d97de1d88fc7 280 PANTHER PTHR13903 1 279 1.2E-115 T 22-04-2016 IPR012093 Pirin TOLA_RS14960 39d7e67073b946aba3a4d97de1d88fc7 280 PIRSF PIRSF006232 4 280 1.7E-95 T 22-04-2016 IPR012093 Pirin TOLA_RS14960 39d7e67073b946aba3a4d97de1d88fc7 280 SUPERFAMILY SSF51182 9 279 1.7E-83 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS14960 39d7e67073b946aba3a4d97de1d88fc7 280 Pfam PF05726 Pirin C-terminal cupin domain 178 279 9.9E-28 T 22-04-2016 IPR008778 Pirin, C-terminal domain TOLA_RS14960 39d7e67073b946aba3a4d97de1d88fc7 280 Pfam PF02678 Pirin 25 123 7.1E-38 T 22-04-2016 IPR003829 Pirin, N-terminal domain TOLA_RS14960 39d7e67073b946aba3a4d97de1d88fc7 280 PANTHER PTHR13903:SF8 1 279 1.2E-115 T 22-04-2016 TOLA_RS07360 08003ab6ee82ce0964a68c83c0ce722f 135 ProSitePatterns PS00935 Glyoxalase I signature 2. 69 81 - T 22-04-2016 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|UniPathway: UPA00619 TOLA_RS07360 08003ab6ee82ce0964a68c83c0ce722f 135 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 22-04-2016 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|UniPathway: UPA00619 TOLA_RS07360 08003ab6ee82ce0964a68c83c0ce722f 135 PANTHER PTHR10374 1 125 1.6E-62 T 22-04-2016 TOLA_RS07360 08003ab6ee82ce0964a68c83c0ce722f 135 Gene3D G3DSA:3.10.180.10 1 127 4.6E-48 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TOLA_RS07360 08003ab6ee82ce0964a68c83c0ce722f 135 SUPERFAMILY SSF54593 1 128 8.19E-37 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TOLA_RS07360 08003ab6ee82ce0964a68c83c0ce722f 135 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 133 7.2E-67 T 22-04-2016 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|UniPathway: UPA00619 TOLA_RS07360 08003ab6ee82ce0964a68c83c0ce722f 135 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 123 6.6E-26 T 22-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TOLA_RS16195 addbd1305af3673a9e7891a28fa9a5f5 152 Gene3D G3DSA:3.40.1400.10 2 147 2.7E-56 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS16195 addbd1305af3673a9e7891a28fa9a5f5 152 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 4 143 2.5E-43 T 22-04-2016 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 TOLA_RS16195 addbd1305af3673a9e7891a28fa9a5f5 152 PANTHER PTHR30345 3 147 3.6E-66 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS16195 addbd1305af3673a9e7891a28fa9a5f5 152 SUPERFAMILY SSF89623 3 145 1.05E-50 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS16195 addbd1305af3673a9e7891a28fa9a5f5 152 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 4 146 7.4E-45 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS16195 addbd1305af3673a9e7891a28fa9a5f5 152 Pfam PF02502 Ribose/Galactose Isomerase 4 142 1.6E-50 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS16195 addbd1305af3673a9e7891a28fa9a5f5 152 PIRSF PIRSF005384 2 148 5.0E-52 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 PANTHER PTHR32063 1 1012 0.0 T 22-04-2016 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 SUPERFAMILY SSF82714 710 792 2.75E-17 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 Gene3D G3DSA:3.30.2090.10 183 262 5.0E-13 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 Gene3D G3DSA:3.30.2090.10 710 791 2.3E-18 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 Pfam PF00873 AcrB/AcrD/AcrF family 4 1011 0.0 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 SUPERFAMILY SSF82693 558 656 2.35E-14 T 22-04-2016 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 Gene3D G3DSA:3.30.70.1430 560 656 6.6E-12 T 22-04-2016 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 PANTHER PTHR32063:SF21 1 1012 0.0 T 22-04-2016 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 SUPERFAMILY SSF82866 290 490 1.7E-50 T 22-04-2016 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 SUPERFAMILY SSF82693 136 182 1.92E-21 T 22-04-2016 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 SUPERFAMILY SSF82693 268 324 1.92E-21 T 22-04-2016 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 SUPERFAMILY SSF82693 40 127 2.27E-23 T 22-04-2016 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 Gene3D G3DSA:1.20.1640.10 285 493 3.1E-59 T 22-04-2016 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 Gene3D G3DSA:3.30.70.1430 40 140 1.8E-28 T 22-04-2016 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 Gene3D G3DSA:1.10.3850.10 799 1012 1.9E-51 T 22-04-2016 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 4.57E-71 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 4.57E-71 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 4.57E-71 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 4.57E-71 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 4.57E-71 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 PRINTS PR00702 Acriflavin resistance protein family signature 611 625 4.57E-71 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 PRINTS PR00702 Acriflavin resistance protein family signature 544 561 4.57E-71 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 4.57E-71 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 4.57E-71 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 SUPERFAMILY SSF82714 183 264 1.7E-13 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS11660 e02d8af5d1c82babcc1fd1e78682dd07 1023 SUPERFAMILY SSF82866 793 1016 2.49E-41 T 22-04-2016 TOLA_RS07445 73c65c7ebfc1c9be0654c889ebf9d9a8 255 SUPERFAMILY SSF53335 4 255 9.51E-37 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07445 73c65c7ebfc1c9be0654c889ebf9d9a8 255 Gene3D G3DSA:3.40.50.150 39 255 1.5E-31 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07445 73c65c7ebfc1c9be0654c889ebf9d9a8 255 Pfam PF08241 Methyltransferase domain 49 146 1.8E-19 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 TOLA_RS07445 73c65c7ebfc1c9be0654c889ebf9d9a8 255 PANTHER PTHR10108:SF919 1 199 8.6E-34 T 22-04-2016 TOLA_RS07445 73c65c7ebfc1c9be0654c889ebf9d9a8 255 PANTHER PTHR10108 1 199 8.6E-34 T 22-04-2016 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 PANTHER PTHR11632:SF50 3 583 0.0 T 22-04-2016 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 580 4.5E-231 T 22-04-2016 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 360 382 5.5E-8 T 22-04-2016 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 5.5E-8 T 22-04-2016 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 SUPERFAMILY SSF51905 361 420 3.38E-72 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 SUPERFAMILY SSF51905 4 250 3.38E-72 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 PIRSF PIRSF000171 1 576 1.5E-38 T 22-04-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 Pfam PF00890 FAD binding domain 7 397 6.3E-109 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 Gene3D G3DSA:3.50.50.60 353 418 2.6E-101 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 Gene3D G3DSA:3.50.50.60 5 233 2.6E-101 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 375 382 5.6E-5 T 22-04-2016 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 5.6E-5 T 22-04-2016 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 Pfam PF02910 Fumarate reductase flavoprotein C-term 453 580 5.7E-40 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 TIGRFAM TIGR01176 fum_red_Fp: fumarate reductase (quinol), flavoprotein subunit 4 581 0.0 T 22-04-2016 IPR005884 Fumarate reductase, flavoprotein subunit GO:0009061|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.4|KEGG: 00620+1.3.5.4|KEGG: 00650+1.3.5.4|KEGG: 00720+1.3.5.4|MetaCyc: PWY-5392|MetaCyc: PWY-5913|MetaCyc: PWY-7384 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 PANTHER PTHR11632 3 583 0.0 T 22-04-2016 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 Gene3D G3DSA:4.10.80.40 551 576 1.9E-17 T 22-04-2016 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 Gene3D G3DSA:1.20.58.100 440 550 4.6E-35 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 22-04-2016 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 SUPERFAMILY SSF56425 227 358 4.34E-40 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 Gene3D G3DSA:3.90.700.10 234 352 2.8E-34 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain TOLA_RS12680 eafd25df2f16f078312815dba7c4e951 589 SUPERFAMILY SSF46977 445 581 9.16E-46 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 TOLA_RS03250 d6851cc38df347ce2168cd5e3f2ab474 244 Hamap MF_00468 Sulfate transporter CysZ [cysZ]. 6 244 26.048 T 22-04-2016 IPR022985 Sulfate transporter CysZ GO:0000103|GO:0005887|GO:0015116 TOLA_RS03250 d6851cc38df347ce2168cd5e3f2ab474 244 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 12 227 8.2E-42 T 22-04-2016 TOLA_RS03250 d6851cc38df347ce2168cd5e3f2ab474 244 PANTHER PTHR37468 1 239 2.9E-74 T 22-04-2016 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 531 547 1.8E-27 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 462 481 1.8E-27 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 554 562 1.8E-27 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 500 511 1.8E-27 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 425 434 1.8E-27 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 391 398 1.8E-27 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 275 285 1.8E-27 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 487 496 1.8E-27 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 Pfam PF00667 FAD binding domain 237 430 2.8E-29 T 22-04-2016 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 10 605 1.4E-237 T 22-04-2016 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 Pfam PF00175 Oxidoreductase NAD-binding domain 463 569 1.9E-19 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PANTHER PTHR19384 69 605 3.6E-202 T 22-04-2016 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 SUPERFAMILY SSF63380 234 452 1.15E-63 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 Gene3D G3DSA:2.40.30.10 389 460 2.1E-39 T 22-04-2016 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 Gene3D G3DSA:2.40.30.10 234 285 2.1E-39 T 22-04-2016 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PANTHER PTHR19384:SF76 69 605 3.6E-202 T 22-04-2016 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 SUPERFAMILY SSF52343 450 605 2.36E-53 T 22-04-2016 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 SUPERFAMILY SSF52218 69 214 2.1E-42 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 Pfam PF00258 Flavodoxin 71 193 3.0E-27 T 22-04-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 Gene3D G3DSA:3.40.50.80 461 604 1.5E-61 T 22-04-2016 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PRINTS PR00369 Flavodoxin signature 150 160 7.4E-11 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PRINTS PR00369 Flavodoxin signature 118 129 7.4E-11 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PRINTS PR00369 Flavodoxin signature 70 83 7.4E-11 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 Gene3D G3DSA:1.20.990.10 286 388 1.5E-33 T 22-04-2016 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 Gene3D G3DSA:3.40.50.360 62 214 3.6E-42 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS11965 f756707f103490d311958ae80eb7134d 605 PIRSF PIRSF000207 1 605 2.5E-247 T 22-04-2016 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0000103|GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS06775 fcfd697f731dce948095771deda44a13 538 PANTHER PTHR11559:SF142 4 517 6.5E-110 T 22-04-2016 TOLA_RS06775 fcfd697f731dce948095771deda44a13 538 Pfam PF00135 Carboxylesterase family 31 519 2.4E-89 T 22-04-2016 IPR002018 Carboxylesterase, type B TOLA_RS06775 fcfd697f731dce948095771deda44a13 538 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 201 216 - T 22-04-2016 IPR019826 Carboxylesterase type B, active site TOLA_RS06775 fcfd697f731dce948095771deda44a13 538 SUPERFAMILY SSF53474 31 520 3.21E-91 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS06775 fcfd697f731dce948095771deda44a13 538 Gene3D G3DSA:3.40.50.1820 27 525 7.7E-112 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS06775 fcfd697f731dce948095771deda44a13 538 PANTHER PTHR11559 4 517 6.5E-110 T 22-04-2016 TOLA_RS06580 72da5c891c8279481eea2156dc56e0b8 439 Gene3D G3DSA:3.30.465.10 343 425 3.3E-28 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 TOLA_RS06580 72da5c891c8279481eea2156dc56e0b8 439 SMART SM01091 346 426 1.0E-29 T 22-04-2016 IPR005170 Transporter-associated domain TOLA_RS06580 72da5c891c8279481eea2156dc56e0b8 439 Gene3D G3DSA:3.10.580.10 198 342 6.8E-13 T 22-04-2016 TOLA_RS06580 72da5c891c8279481eea2156dc56e0b8 439 SUPERFAMILY SSF54631 199 335 1.26E-21 T 22-04-2016 TOLA_RS06580 72da5c891c8279481eea2156dc56e0b8 439 PANTHER PTHR22777:SF16 1 429 2.4E-255 T 22-04-2016 TOLA_RS06580 72da5c891c8279481eea2156dc56e0b8 439 Pfam PF03471 Transporter associated domain 347 424 2.3E-22 T 22-04-2016 IPR005170 Transporter-associated domain TOLA_RS06580 72da5c891c8279481eea2156dc56e0b8 439 Pfam PF00571 CBS domain 286 333 0.0011 T 22-04-2016 IPR000644 CBS domain TOLA_RS06580 72da5c891c8279481eea2156dc56e0b8 439 PANTHER PTHR22777 1 429 2.4E-255 T 22-04-2016 TOLA_RS06580 72da5c891c8279481eea2156dc56e0b8 439 Pfam PF01595 Domain of unknown function DUF21 7 197 1.4E-38 T 22-04-2016 IPR002550 Domain of unknown function DUF21 TOLA_RS06580 72da5c891c8279481eea2156dc56e0b8 439 SUPERFAMILY SSF56176 344 431 6.54E-24 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 TOLA_RS01635 879dd868037bc82f8dfe406de98d522b 140 SUPERFAMILY SSF46785 4 133 3.47E-44 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01635 879dd868037bc82f8dfe406de98d522b 140 PANTHER PTHR33202 3 133 1.6E-41 T 22-04-2016 TOLA_RS01635 879dd868037bc82f8dfe406de98d522b 140 Pfam PF01475 Ferric uptake regulator family 8 127 2.4E-43 T 22-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TOLA_RS01635 879dd868037bc82f8dfe406de98d522b 140 Gene3D G3DSA:1.10.10.10 3 80 2.0E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS04700 8b8da682ae4032fad68a732b8dc02220 220 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 2 187 31.962 T 22-04-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 TOLA_RS04700 8b8da682ae4032fad68a732b8dc02220 220 PANTHER PTHR10520 1 193 6.0E-105 T 22-04-2016 TOLA_RS04700 8b8da682ae4032fad68a732b8dc02220 220 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 191 4.8E-83 T 22-04-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 TOLA_RS04700 8b8da682ae4032fad68a732b8dc02220 220 SUPERFAMILY SSF53328 1 198 3.01E-68 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS04700 8b8da682ae4032fad68a732b8dc02220 220 Gene3D G3DSA:3.40.50.170 2 194 1.8E-73 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS04700 8b8da682ae4032fad68a732b8dc02220 220 Pfam PF00551 Formyl transferase 1 181 1.1E-66 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS04700 8b8da682ae4032fad68a732b8dc02220 220 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 22-04-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS09490 548a44bc8df1dfdecbca1d7cca8084cd 413 Pfam PF07805 HipA-like N-terminal domain 149 220 7.3E-16 T 22-04-2016 IPR012894 HipA, N-terminal subdomain 2 TOLA_RS09490 548a44bc8df1dfdecbca1d7cca8084cd 413 Pfam PF13657 HipA N-terminal domain 15 110 2.2E-12 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 TOLA_RS09490 548a44bc8df1dfdecbca1d7cca8084cd 413 Pfam PF07804 HipA-like C-terminal domain 226 362 3.9E-28 T 22-04-2016 IPR012893 HipA-like, C-terminal TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 256 329 1.0E-35 T 22-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 60 156 2.4E-22 T 22-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 SUPERFAMILY SSF56553 53 178 8.24E-40 T 22-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 Gene3D G3DSA:3.30.1360.10 10 51 6.5E-10 T 22-04-2016 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 PANTHER PTHR32108 1 329 2.0E-153 T 22-04-2016 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 SMART SM00662 23 234 3.8E-101 T 22-04-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 Gene3D G3DSA:2.170.120.12 53 177 3.0E-38 T 22-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 SUPERFAMILY SSF55257 179 233 4.51E-30 T 22-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 SUPERFAMILY SSF55257 7 53 4.51E-30 T 22-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 PANTHER PTHR32108:SF0 1 329 2.0E-153 T 22-04-2016 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 SUPERFAMILY SSF47789 251 325 1.31E-25 T 22-04-2016 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 316 3.4E-108 T 22-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 Gene3D G3DSA:1.10.150.20 245 327 1.7E-37 T 22-04-2016 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 248 308 8.0E-24 T 22-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 228 1.3E-23 T 22-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS00645 ee374d30f971ff268f3a38b7392ed984 329 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 317 34.291 T 22-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 Pfam PF08238 Sel1 repeat 178 211 2.6E-10 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 Pfam PF08238 Sel1 repeat 214 246 4.4E-5 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 Pfam PF08238 Sel1 repeat 107 138 0.0041 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 Pfam PF08238 Sel1 repeat 148 176 5.0E-7 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 Pfam PF08238 Sel1 repeat 70 104 3.3E-7 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 SUPERFAMILY SSF81901 48 247 2.18E-49 T 22-04-2016 TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 Gene3D G3DSA:1.25.40.10 49 260 1.9E-55 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 PANTHER PTHR11102 50 247 2.8E-49 T 22-04-2016 TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 SMART SM00671 177 211 1.5E-9 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 SMART SM00671 141 176 1.3E-4 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 SMART SM00671 69 104 6.2E-10 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 SMART SM00671 212 247 5.7E-6 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS06265 79de18d09d6c20f0c2f5c500bd03638e 282 SMART SM00671 105 140 1.2E-7 T 22-04-2016 IPR006597 Sel1-like repeat TOLA_RS08300 6728714192d0bc07a9e0dabbf8c979fc 158 Pfam PF01037 Lrp/AsnC ligand binding domain 82 141 4.7E-13 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TOLA_RS08300 6728714192d0bc07a9e0dabbf8c979fc 158 PANTHER PTHR30154 1 153 6.4E-36 T 22-04-2016 TOLA_RS08300 6728714192d0bc07a9e0dabbf8c979fc 158 SUPERFAMILY SSF54909 71 152 2.95E-13 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel TOLA_RS08300 6728714192d0bc07a9e0dabbf8c979fc 158 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 4.4E-15 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS08300 6728714192d0bc07a9e0dabbf8c979fc 158 SUPERFAMILY SSF46785 2 60 5.41E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08300 6728714192d0bc07a9e0dabbf8c979fc 158 Gene3D G3DSA:3.30.70.920 55 152 6.6E-16 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TOLA_RS08300 6728714192d0bc07a9e0dabbf8c979fc 158 Gene3D G3DSA:1.10.10.10 1 50 3.1E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08300 6728714192d0bc07a9e0dabbf8c979fc 158 SMART SM00344 3 112 4.3E-26 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TOLA_RS08300 6728714192d0bc07a9e0dabbf8c979fc 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.6E-14 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS08300 6728714192d0bc07a9e0dabbf8c979fc 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.6E-14 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS08300 6728714192d0bc07a9e0dabbf8c979fc 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.6E-14 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS02900 2270b5a62eb86d3a9515e6002fe5d876 330 Gene3D G3DSA:3.40.50.300 127 330 2.8E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02900 2270b5a62eb86d3a9515e6002fe5d876 330 PANTHER PTHR40690 52 328 3.7E-68 T 22-04-2016 TOLA_RS02900 2270b5a62eb86d3a9515e6002fe5d876 330 PANTHER PTHR40690:SF1 52 328 3.7E-68 T 22-04-2016 TOLA_RS02900 2270b5a62eb86d3a9515e6002fe5d876 330 PIRSF PIRSF026760 3 330 4.7E-98 T 22-04-2016 IPR011669 Protein of unknown function DUF1611 TOLA_RS02900 2270b5a62eb86d3a9515e6002fe5d876 330 SUPERFAMILY SSF52540 1 330 5.84E-105 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02900 2270b5a62eb86d3a9515e6002fe5d876 330 Pfam PF07755 Protein of unknown function (DUF1611) 40 327 9.4E-106 T 22-04-2016 IPR011669 Protein of unknown function DUF1611 TOLA_RS02900 2270b5a62eb86d3a9515e6002fe5d876 330 Gene3D G3DSA:3.40.50.720 1 126 1.7E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS05500 ad5983408d0d558e667a02bd379a153c 615 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 145 582 56.247 T 22-04-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 TOLA_RS05500 ad5983408d0d558e667a02bd379a153c 615 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 145 579 4.4E-218 T 22-04-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 TOLA_RS05500 ad5983408d0d558e667a02bd379a153c 615 Pfam PF01964 Radical SAM ThiC family 147 577 2.2E-199 T 22-04-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 TOLA_RS05500 ad5983408d0d558e667a02bd379a153c 615 PANTHER PTHR30557 138 615 0.0 T 22-04-2016 TOLA_RS05500 ad5983408d0d558e667a02bd379a153c 615 PANTHER PTHR30557 1 105 0.0 T 22-04-2016 TOLA_RS05500 ad5983408d0d558e667a02bd379a153c 615 Pfam PF13667 ThiC-associated domain 26 107 2.2E-32 T 22-04-2016 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 TOLA_RS05500 ad5983408d0d558e667a02bd379a153c 615 PANTHER PTHR30557:SF1 138 615 0.0 T 22-04-2016 TOLA_RS05500 ad5983408d0d558e667a02bd379a153c 615 PANTHER PTHR30557:SF1 1 105 0.0 T 22-04-2016 TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 SMART SM01003 4 137 6.6E-74 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 3.7E-44 T 22-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 PIRSF PIRSF000183 1 371 4.1E-145 T 22-04-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 Gene3D G3DSA:3.40.50.1770 3 178 5.8E-60 T 22-04-2016 TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 SUPERFAMILY SSF51735 137 303 6.41E-49 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 2.3E-79 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 Gene3D G3DSA:3.40.50.1770 205 355 7.2E-30 T 22-04-2016 TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 Gene3D G3DSA:3.50.50.60 179 204 4.0E-8 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 1.4E-145 T 22-04-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 SMART SM01002 149 297 1.3E-84 T 22-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 PANTHER PTHR10160 1 371 9.8E-191 T 22-04-2016 TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 SUPERFAMILY SSF52283 1 137 1.11E-62 T 22-04-2016 TOLA_RS11770 b22a7b6ad3266024c89c407c7ccfc826 374 SUPERFAMILY SSF52283 305 355 1.11E-62 T 22-04-2016 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 SUPERFAMILY SSF51215 20 104 6.54E-11 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 SMART SM00342 187 270 2.6E-23 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 PANTHER PTHR11019:SF86 29 266 8.1E-45 T 22-04-2016 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 SUPERFAMILY SSF46689 171 221 4.12E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 Pfam PF12833 Helix-turn-helix domain 193 270 2.5E-23 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 254 270 4.1E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 239 254 4.1E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 Gene3D G3DSA:1.10.10.60 224 273 4.5E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 PANTHER PTHR11019 29 266 8.1E-45 T 22-04-2016 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 224 266 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 SUPERFAMILY SSF46689 223 273 9.41E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 Pfam PF02311 AraC-like ligand binding domain 18 154 1.3E-8 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 Gene3D G3DSA:2.60.120.10 16 87 3.9E-10 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS05345 ab228e4c12137a0aed0d8090a1752df7 277 Gene3D G3DSA:1.10.10.60 168 223 5.1E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS11410 9a0ece2f7d7f6683550fb94d066058ff 152 SUPERFAMILY SSF75420 4 83 4.71E-26 T 22-04-2016 IPR028989 Ribosome maturation factor RimP, N-terminal TOLA_RS11410 9a0ece2f7d7f6683550fb94d066058ff 152 Gene3D G3DSA:2.30.30.180 88 148 7.7E-12 T 22-04-2016 IPR028998 Ribosome maturation factor RimP, C-terminal TOLA_RS11410 9a0ece2f7d7f6683550fb94d066058ff 152 SUPERFAMILY SSF74942 84 151 2.48E-17 T 22-04-2016 IPR028998 Ribosome maturation factor RimP, C-terminal TOLA_RS11410 9a0ece2f7d7f6683550fb94d066058ff 152 Gene3D G3DSA:3.30.300.70 3 80 1.3E-32 T 22-04-2016 IPR028989 Ribosome maturation factor RimP, N-terminal TOLA_RS11410 9a0ece2f7d7f6683550fb94d066058ff 152 Pfam PF02576 Putative ribosome maturation factor RimP 14 147 2.8E-46 T 22-04-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 TOLA_RS11410 9a0ece2f7d7f6683550fb94d066058ff 152 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 151 24.874 T 22-04-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 TOLA_RS11410 9a0ece2f7d7f6683550fb94d066058ff 152 PANTHER PTHR33867:SF1 1 152 3.2E-55 T 22-04-2016 TOLA_RS11410 9a0ece2f7d7f6683550fb94d066058ff 152 PANTHER PTHR33867 1 152 3.2E-55 T 22-04-2016 TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 PANTHER PTHR18895:SF62 401 678 3.3E-115 T 22-04-2016 TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 PIRSF PIRSF037618 1 703 1.7E-299 T 22-04-2016 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 Gene3D G3DSA:3.40.50.150 147 213 2.2E-27 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 Gene3D G3DSA:3.40.50.150 257 351 2.2E-27 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 4 702 32.94 T 22-04-2016 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 SUPERFAMILY SSF53335 141 216 1.48E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 SUPERFAMILY SSF53335 260 375 1.48E-39 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 455 665 8.4E-22 T 22-04-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 PANTHER PTHR18895 401 678 3.3E-115 T 22-04-2016 TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 Pfam PF01170 Putative RNA methylase family UPF0020 162 376 3.5E-53 T 22-04-2016 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 Pfam PF02926 THUMP domain 25 153 1.8E-10 T 22-04-2016 IPR004114 THUMP domain GO:0003723 TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 194 205 - T 22-04-2016 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 SUPERFAMILY SSF53335 395 701 5.82E-69 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 SMART SM00981 56 154 5.8E-19 T 22-04-2016 IPR004114 THUMP domain GO:0003723 TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 Gene3D G3DSA:3.40.50.150 432 701 3.6E-72 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07250 855b9b32960a3f8b93d9838b37544253 712 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 307 313 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TOLA_RS08515 f8814cb2500e85ba7abc3c858d4b6b99 358 Pfam PF11761 Cobalamin biosynthesis central region 140 222 6.0E-5 T 22-04-2016 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377|UniPathway: UPA00148 TOLA_RS08515 f8814cb2500e85ba7abc3c858d4b6b99 358 PANTHER PTHR37477 204 355 1.1E-55 T 22-04-2016 TOLA_RS08515 f8814cb2500e85ba7abc3c858d4b6b99 358 PANTHER PTHR37477 2 186 1.1E-55 T 22-04-2016 TOLA_RS08515 f8814cb2500e85ba7abc3c858d4b6b99 358 SUPERFAMILY SSF159664 231 356 4.58E-30 T 22-04-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 TOLA_RS08515 f8814cb2500e85ba7abc3c858d4b6b99 358 SUPERFAMILY SSF159672 6 188 6.67E-58 T 22-04-2016 TOLA_RS08515 f8814cb2500e85ba7abc3c858d4b6b99 358 SUPERFAMILY SSF159672 215 245 6.67E-58 T 22-04-2016 TOLA_RS08515 f8814cb2500e85ba7abc3c858d4b6b99 358 PANTHER PTHR37477:SF1 204 355 1.1E-55 T 22-04-2016 TOLA_RS08515 f8814cb2500e85ba7abc3c858d4b6b99 358 PANTHER PTHR37477:SF1 2 186 1.1E-55 T 22-04-2016 TOLA_RS08515 f8814cb2500e85ba7abc3c858d4b6b99 358 Pfam PF11760 Cobalamin synthesis G N-terminal 55 134 4.2E-34 T 22-04-2016 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377|UniPathway: UPA00148 TOLA_RS08515 f8814cb2500e85ba7abc3c858d4b6b99 358 Gene3D G3DSA:3.30.420.180 231 355 4.6E-25 T 22-04-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 TOLA_RS08515 f8814cb2500e85ba7abc3c858d4b6b99 358 Pfam PF01890 Cobalamin synthesis G C-terminus 238 353 2.6E-21 T 22-04-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 SMART SM00433 34 625 6.0E-205 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 Pfam PF01751 Toprim domain 413 522 1.5E-12 T 22-04-2016 IPR006171 Toprim domain TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 Pfam PF00204 DNA gyrase B 218 384 3.0E-40 T 22-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 Gene3D G3DSA:3.30.565.10 15 209 1.4E-76 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 171 5.2E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 ProSitePatterns PS00177 DNA topoisomerase II signature. 416 424 - T 22-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 SUPERFAMILY SSF54211 217 382 7.02E-46 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 Gene3D G3DSA:3.40.50.670 398 611 6.0E-74 T 22-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR00418 DNA topoisomerase II family signature 414 428 3.7E-58 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR00418 DNA topoisomerase II family signature 479 495 3.7E-58 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR00418 DNA topoisomerase II family signature 109 123 3.7E-58 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR00418 DNA topoisomerase II family signature 31 46 3.7E-58 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR00418 DNA topoisomerase II family signature 517 529 3.7E-58 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR00418 DNA topoisomerase II family signature 66 79 3.7E-58 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR00418 DNA topoisomerase II family signature 562 578 3.7E-58 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR00418 DNA topoisomerase II family signature 266 279 3.7E-58 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR00418 DNA topoisomerase II family signature 497 514 3.7E-58 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 559 621 3.0E-24 T 22-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PANTHER PTHR10169:SF45 1 629 0.0 T 22-04-2016 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 2 625 0.0 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 2 629 46.839 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 311 326 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 149 164 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 294 310 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 362 387 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 174 191 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 537 559 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 238 261 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 338 361 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 192 213 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 448 469 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 135 149 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 26 39 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 469 481 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PRINTS PR01098 Topoisomerase IV subunit B signature 503 519 1.2E-124 T 22-04-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 SUPERFAMILY SSF56719 388 622 5.75E-76 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 SMART SM00387 27 173 4.1E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 Gene3D G3DSA:3.30.230.10 217 390 3.6E-46 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 PANTHER PTHR10169 1 629 0.0 T 22-04-2016 TOLA_RS02075 6bd20600442e33db89e0b507afd4840e 630 SUPERFAMILY SSF55874 5 215 3.29E-68 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS02250 b4dea405a3ded362c33b19e5baea4b89 286 SUPERFAMILY SSF52096 15 282 5.69E-78 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS02250 b4dea405a3ded362c33b19e5baea4b89 286 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 124 144 - T 22-04-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 TOLA_RS02250 b4dea405a3ded362c33b19e5baea4b89 286 Gene3D G3DSA:1.10.12.10 224 274 5.1E-31 T 22-04-2016 IPR014748 Crontonase, C-terminal TOLA_RS02250 b4dea405a3ded362c33b19e5baea4b89 286 PANTHER PTHR11941 10 279 7.7E-197 T 22-04-2016 TOLA_RS02250 b4dea405a3ded362c33b19e5baea4b89 286 Gene3D G3DSA:3.90.226.10 23 223 3.4E-70 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS02250 b4dea405a3ded362c33b19e5baea4b89 286 TIGRFAM TIGR01929 menB: naphthoate synthase 23 282 8.1E-147 T 22-04-2016 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 TOLA_RS02250 b4dea405a3ded362c33b19e5baea4b89 286 PANTHER PTHR11941:SF20 10 279 7.7E-197 T 22-04-2016 TOLA_RS02250 b4dea405a3ded362c33b19e5baea4b89 286 Pfam PF00378 Enoyl-CoA hydratase/isomerase 33 280 4.5E-77 T 22-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 TOLA_RS02250 b4dea405a3ded362c33b19e5baea4b89 286 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 16 285 56.217 T 22-04-2016 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 TOLA_RS05975 1245155ab0b33cd08de1069e90ac071d 124 SUPERFAMILY SSF46785 66 121 3.72E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05975 1245155ab0b33cd08de1069e90ac071d 124 Pfam PF13412 Winged helix-turn-helix DNA-binding 69 107 3.6E-10 T 22-04-2016 TOLA_RS05975 1245155ab0b33cd08de1069e90ac071d 124 Gene3D G3DSA:1.10.10.10 69 107 4.0E-9 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS03095 6060c18e8fc75520c9d2532985e21523 403 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 297 309 3.2E-27 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS03095 6060c18e8fc75520c9d2532985e21523 403 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 347 363 3.2E-27 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS03095 6060c18e8fc75520c9d2532985e21523 403 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 230 240 3.2E-27 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS03095 6060c18e8fc75520c9d2532985e21523 403 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 385 402 3.2E-27 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS03095 6060c18e8fc75520c9d2532985e21523 403 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 201 215 3.2E-27 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS03095 6060c18e8fc75520c9d2532985e21523 403 PANTHER PTHR22807:SF33 109 402 2.2E-125 T 22-04-2016 TOLA_RS03095 6060c18e8fc75520c9d2532985e21523 403 SUPERFAMILY SSF53335 118 402 2.15E-66 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS03095 6060c18e8fc75520c9d2532985e21523 403 Gene3D G3DSA:3.30.70.1170 155 208 3.4E-11 T 22-04-2016 TOLA_RS03095 6060c18e8fc75520c9d2532985e21523 403 Gene3D G3DSA:3.40.50.150 211 402 2.3E-49 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS03095 6060c18e8fc75520c9d2532985e21523 403 Pfam PF01189 16S rRNA methyltransferase RsmB/F 222 374 2.3E-39 T 22-04-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS03095 6060c18e8fc75520c9d2532985e21523 403 PANTHER PTHR22807 109 402 2.2E-125 T 22-04-2016 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 SUPERFAMILY SSF54368 3 99 4.32E-37 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 1.7E-32 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 22-04-2016 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 Gene3D G3DSA:3.30.590.10 106 455 4.8E-137 T 22-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 PANTHER PTHR20852:SF15 161 469 5.1E-268 T 22-04-2016 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 PANTHER PTHR20852:SF15 1 138 5.1E-268 T 22-04-2016 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 Gene3D G3DSA:3.10.20.70 3 105 4.2E-41 T 22-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 5 468 2.6E-209 T 22-04-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 SMART SM01230 102 379 1.8E-148 T 22-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 PANTHER PTHR20852 161 469 5.1E-268 T 22-04-2016 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 PANTHER PTHR20852 1 138 5.1E-268 T 22-04-2016 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 Pfam PF00120 Glutamine synthetase, catalytic domain 103 466 1.2E-137 T 22-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 22-04-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 22-04-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TOLA_RS02385 41d2a842617a5207f484f0aa07e983f3 469 SUPERFAMILY SSF55931 102 468 2.06E-136 T 22-04-2016 TOLA_RS15110 32046c785815090dbfeffd9c20b9e841 167 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 25 2.7E-5 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS15110 32046c785815090dbfeffd9c20b9e841 167 Pfam PF12019 Type II transport protein GspH 44 157 3.7E-13 T 22-04-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 TOLA_RS15110 32046c785815090dbfeffd9c20b9e841 167 SUPERFAMILY SSF54523 6 138 1.8E-11 T 22-04-2016 TOLA_RS08350 7a02676bb10ec68af82b224c7ecd7ce1 208 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 92 2.8E-22 T 22-04-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TOLA_RS08350 7a02676bb10ec68af82b224c7ecd7ce1 208 PANTHER PTHR14239 1 185 6.7E-46 T 22-04-2016 TOLA_RS08350 7a02676bb10ec68af82b224c7ecd7ce1 208 SUPERFAMILY SSF51735 1 199 1.81E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS08350 7a02676bb10ec68af82b224c7ecd7ce1 208 Gene3D G3DSA:3.40.50.720 1 191 2.7E-63 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS03180 70405eacd3ef659d49c6e808b3ea30ac 230 Gene3D G3DSA:3.40.50.1580 1 230 7.3E-80 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TOLA_RS03180 70405eacd3ef659d49c6e808b3ea30ac 230 Pfam PF01048 Phosphorylase superfamily 2 227 4.3E-49 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TOLA_RS03180 70405eacd3ef659d49c6e808b3ea30ac 230 PANTHER PTHR21234 1 230 3.1E-62 T 22-04-2016 IPR018017 Nucleoside phosphorylase TOLA_RS03180 70405eacd3ef659d49c6e808b3ea30ac 230 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 230 8.7E-98 T 22-04-2016 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154|UniPathway: UPA00904 TOLA_RS03180 70405eacd3ef659d49c6e808b3ea30ac 230 PANTHER PTHR21234:SF16 1 230 3.1E-62 T 22-04-2016 TOLA_RS03180 70405eacd3ef659d49c6e808b3ea30ac 230 SUPERFAMILY SSF53167 1 230 2.36E-71 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TOLA_RS03180 70405eacd3ef659d49c6e808b3ea30ac 230 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 47.973 T 22-04-2016 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154|UniPathway: UPA00904 TOLA_RS13115 12f00db3f505e958676af32db57c9278 378 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 374 2.5E-164 T 22-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 TOLA_RS13115 12f00db3f505e958676af32db57c9278 378 PIRSF PIRSF006078 1 376 9.6E-146 T 22-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 TOLA_RS13115 12f00db3f505e958676af32db57c9278 378 PANTHER PTHR21599 1 375 3.6E-220 T 22-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 TOLA_RS13115 12f00db3f505e958676af32db57c9278 378 Pfam PF02595 Glycerate kinase family 3 373 1.1E-152 T 22-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 TOLA_RS13115 12f00db3f505e958676af32db57c9278 378 Gene3D G3DSA:3.90.1510.10 42 275 2.3E-100 T 22-04-2016 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 TOLA_RS13115 12f00db3f505e958676af32db57c9278 378 PANTHER PTHR21599:SF4 1 375 3.6E-220 T 22-04-2016 TOLA_RS13115 12f00db3f505e958676af32db57c9278 378 SUPERFAMILY SSF110738 1 375 8.76E-144 T 22-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 PANTHER PTHR23355:SF9 5 804 3.4E-284 T 22-04-2016 TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 SUPERFAMILY SSF50249 645 724 5.46E-22 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 ProSitePatterns PS01175 Ribonuclease II family signature. 556 580 - T 22-04-2016 IPR022966 Ribonuclease II/R, conserved site TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 SMART SM00316 644 727 4.9E-15 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 SMART SM00357 87 146 2.9E-12 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 Pfam PF08461 Ribonuclease R winged-helix domain 24 84 1.7E-10 T 22-04-2016 IPR013668 Ribonuclease R winged-helix domain TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 SMART SM00955 261 589 2.2E-182 T 22-04-2016 TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 68 727 2.9E-251 T 22-04-2016 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 SUPERFAMILY SSF50249 68 147 5.57E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 Pfam PF00773 RNB domain 261 587 5.7E-106 T 22-04-2016 TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 TIGRFAM TIGR02063 RNase_R: ribonuclease R 20 728 9.1E-272 T 22-04-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 Hamap MF_01895 Ribonuclease R [rnr]. 39 727 57.762 T 22-04-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 Gene3D G3DSA:2.40.50.140 646 726 4.2E-23 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 PANTHER PTHR23355 5 804 3.4E-284 T 22-04-2016 TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 Pfam PF00575 S1 RNA binding domain 644 724 6.8E-12 T 22-04-2016 IPR003029 S1 domain GO:0003676 TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 Pfam PF08206 Ribonuclease B OB domain 88 144 6.3E-20 T 22-04-2016 IPR013223 Ribonuclease B, N-terminal OB domain TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 SUPERFAMILY SSF50249 221 644 6.43E-143 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13250 a3ada88e5742b9eb4e46ca06ce1970f1 806 SUPERFAMILY SSF50249 139 238 3.43E-15 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 Pfam PF04055 Radical SAM superfamily 146 323 1.2E-29 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 SMART SM00729 140 365 9.2E-52 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 SUPERFAMILY SSF102114 126 371 3.66E-52 T 22-04-2016 TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 Pfam PF00919 Uncharacterized protein family UPF0004 9 95 4.7E-21 T 22-04-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 9 438 5.4E-190 T 22-04-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 PANTHER PTHR11918:SF57 1 442 3.5E-241 T 22-04-2016 TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 PANTHER PTHR11918 1 442 3.5E-241 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 8 440 62.974 T 22-04-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 Gene3D G3DSA:2.40.50.140 380 441 1.3E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 Gene3D G3DSA:3.80.30.20 138 375 1.4E-73 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 144 164 - T 22-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 Pfam PF01938 TRAM domain 378 441 7.7E-5 T 22-04-2016 IPR002792 TRAM domain TOLA_RS05030 d7fec8e9cd0117c4a20b73f13948e067 442 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 9 438 5.4E-108 T 22-04-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 SMART SM00387 316 428 4.0E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 95 424 2.2E-137 T 22-04-2016 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 SUPERFAMILY SSF55874 260 425 4.85E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 PANTHER PTHR24423 7 432 4.2E-166 T 22-04-2016 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 SUPERFAMILY SSF47384 192 269 6.47E-20 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 Pfam PF11808 Domain of unknown function (DUF3329) 7 91 1.6E-26 T 22-04-2016 IPR021766 Protein of unknown function DUF3329 GO:0004673 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 SMART SM00388 205 271 3.3E-22 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 426 6.1E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 Pfam PF00512 His Kinase A (phospho-acceptor) domain 206 269 5.8E-19 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 Gene3D G3DSA:3.30.565.10 258 425 2.0E-42 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 Gene3D G3DSA:1.10.287.130 197 257 3.2E-21 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 SUPERFAMILY SSF55785 87 197 1.73E-8 T 22-04-2016 IPR000014 PAS domain TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 Gene3D G3DSA:3.30.450.20 98 196 1.1E-6 T 22-04-2016 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 PANTHER PTHR24423:SF554 7 432 4.2E-166 T 22-04-2016 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 3.6E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 425 3.6E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 3.6E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS10505 0aae9b9003398a464051db6bbc328005 432 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 3.6E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS10355 82eab92f7a511c40ba12e18c8d4ebbf6 163 Gene3D G3DSA:1.20.120.330 76 125 3.7E-4 T 22-04-2016 TOLA_RS10355 82eab92f7a511c40ba12e18c8d4ebbf6 163 SUPERFAMILY SSF81593 18 129 1.37E-14 T 22-04-2016 TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 SUPERFAMILY SSF55781 21 166 1.13E-8 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 274 289 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 Pfam PF00158 Sigma-54 interaction domain 188 354 4.3E-68 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 Gene3D G3DSA:3.30.450.40 17 166 1.6E-4 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 401 410 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 Gene3D G3DSA:1.10.8.60 361 409 4.7E-19 T 22-04-2016 TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 Gene3D G3DSA:3.40.50.300 186 360 6.8E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 212 225 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 SUPERFAMILY SSF46689 460 513 4.17E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 SMART SM00382 208 355 1.3E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 Gene3D G3DSA:1.10.10.60 410 513 3.0E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 PANTHER PTHR32071:SF35 187 513 1.2E-156 T 22-04-2016 TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 SUPERFAMILY SSF52540 187 422 1.05E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09340 cbfea68dc373f0cf9a1bfe6503695eeb 514 PANTHER PTHR32071 187 513 1.2E-156 T 22-04-2016 TOLA_RS12060 f648d923e1c9806eb2a398573c833131 276 Gene3D G3DSA:3.60.21.10 1 132 1.2E-52 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS12060 f648d923e1c9806eb2a398573c833131 276 Gene3D G3DSA:3.60.21.10 169 267 1.2E-52 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS12060 f648d923e1c9806eb2a398573c833131 276 SUPERFAMILY SSF56300 1 258 1.62E-52 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS12060 f648d923e1c9806eb2a398573c833131 276 PIRSF PIRSF000903 1 273 2.3E-112 T 22-04-2016 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 TOLA_RS12060 f648d923e1c9806eb2a398573c833131 276 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 266 2.1E-108 T 22-04-2016 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 TOLA_RS12060 f648d923e1c9806eb2a398573c833131 276 PANTHER PTHR24032 1 265 2.2E-131 T 22-04-2016 TOLA_RS12060 f648d923e1c9806eb2a398573c833131 276 Pfam PF00149 Calcineurin-like phosphoesterase 3 130 2.8E-9 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 TOLA_RS12060 f648d923e1c9806eb2a398573c833131 276 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 271 45.549 T 22-04-2016 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 TOLA_RS12060 f648d923e1c9806eb2a398573c833131 276 PANTHER PTHR24032:SF27 1 265 2.2E-131 T 22-04-2016 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 Gene3D G3DSA:1.10.10.60 407 474 4.0E-22 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 Pfam PF02954 Bacterial regulatory protein, Fis family 431 471 4.5E-16 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 5 471 2.9E-232 T 22-04-2016 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 SUPERFAMILY SSF52172 4 188 6.26E-44 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 Pfam PF00072 Response regulator receiver domain 5 116 3.2E-29 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 SUPERFAMILY SSF46689 383 473 2.15E-21 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 454 474 4.4E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 437 454 4.4E-9 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 SMART SM00448 3 116 1.3E-37 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 167 180 - T 22-04-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 Gene3D G3DSA:3.40.50.300 149 315 3.2E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 PANTHER PTHR32071 1 474 7.8E-242 T 22-04-2016 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 356 365 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 SMART SM00382 163 306 1.0E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 Gene3D G3DSA:3.40.50.2300 3 148 3.7E-37 T 22-04-2016 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 Gene3D G3DSA:1.10.8.60 316 391 1.8E-23 T 22-04-2016 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 SUPERFAMILY SSF52540 142 386 2.09E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 PANTHER PTHR32071:SF15 1 474 7.8E-242 T 22-04-2016 TOLA_RS02370 55b521749b87462f11574d9e6e80a03b 474 Pfam PF00158 Sigma-54 interaction domain 143 310 4.5E-71 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TOLA_RS04060 46dad199699d4a05a8affe8330da5558 188 PANTHER PTHR11019:SF4 2 187 2.7E-59 T 22-04-2016 TOLA_RS04060 46dad199699d4a05a8affe8330da5558 188 Gene3D G3DSA:3.40.50.880 2 187 6.8E-56 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS04060 46dad199699d4a05a8affe8330da5558 188 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 6 184 2.0E-60 T 22-04-2016 IPR006287 DJ-1 TOLA_RS04060 46dad199699d4a05a8affe8330da5558 188 PANTHER PTHR11019 2 187 2.7E-59 T 22-04-2016 TOLA_RS04060 46dad199699d4a05a8affe8330da5558 188 SUPERFAMILY SSF52317 4 186 2.04E-49 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS04060 46dad199699d4a05a8affe8330da5558 188 Pfam PF01965 DJ-1/PfpI family 4 171 2.3E-42 T 22-04-2016 IPR002818 DJ-1/PfpI TOLA_RS00110 ff38eef631b8f7d2c9b630707ca73b9b 174 SUPERFAMILY SSF52218 4 167 1.49E-29 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS00110 ff38eef631b8f7d2c9b630707ca73b9b 174 Pfam PF12724 Flavodoxin domain 6 152 4.7E-47 T 22-04-2016 IPR026816 Flavodoxin domain TOLA_RS00110 ff38eef631b8f7d2c9b630707ca73b9b 174 Gene3D G3DSA:3.40.50.360 2 172 2.8E-20 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS00110 ff38eef631b8f7d2c9b630707ca73b9b 174 PANTHER PTHR38030 1 172 8.8E-72 T 22-04-2016 TOLA_RS00110 ff38eef631b8f7d2c9b630707ca73b9b 174 PANTHER PTHR38030:SF2 1 172 8.8E-72 T 22-04-2016 TOLA_RS00785 a98eb349d1aa5bbeb58a2654fd6ffdb9 318 Gene3D G3DSA:3.40.50.170 7 211 2.8E-76 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS00785 a98eb349d1aa5bbeb58a2654fd6ffdb9 318 Pfam PF02911 Formyl transferase, C-terminal domain 210 306 3.6E-29 T 22-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS00785 a98eb349d1aa5bbeb58a2654fd6ffdb9 318 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 8 311 4.3E-106 T 22-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS00785 a98eb349d1aa5bbeb58a2654fd6ffdb9 318 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 8 310 36.711 T 22-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS00785 a98eb349d1aa5bbeb58a2654fd6ffdb9 318 SUPERFAMILY SSF50486 211 310 8.95E-32 T 22-04-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 TOLA_RS00785 a98eb349d1aa5bbeb58a2654fd6ffdb9 318 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 139 162 - T 22-04-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS00785 a98eb349d1aa5bbeb58a2654fd6ffdb9 318 Gene3D G3DSA:3.10.25.10 213 308 2.0E-33 T 22-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS00785 a98eb349d1aa5bbeb58a2654fd6ffdb9 318 Pfam PF00551 Formyl transferase 9 183 3.0E-48 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS00785 a98eb349d1aa5bbeb58a2654fd6ffdb9 318 PANTHER PTHR11138 8 313 2.5E-122 T 22-04-2016 TOLA_RS00785 a98eb349d1aa5bbeb58a2654fd6ffdb9 318 SUPERFAMILY SSF53328 7 210 1.7E-69 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS04925 8a15c42be1f322aae50bd481872b4bff 91 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 26.868 T 22-04-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 TOLA_RS04925 8a15c42be1f322aae50bd481872b4bff 91 PIRSF PIRSF029827 1 90 1.7E-40 T 22-04-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 TOLA_RS04925 8a15c42be1f322aae50bd481872b4bff 91 SUPERFAMILY SSF111148 1 90 1.15E-39 T 22-04-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 TOLA_RS04925 8a15c42be1f322aae50bd481872b4bff 91 Gene3D G3DSA:1.10.3880.10 1 90 6.7E-43 T 22-04-2016 TOLA_RS04925 8a15c42be1f322aae50bd481872b4bff 91 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 5.8E-41 T 22-04-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 TOLA_RS04925 8a15c42be1f322aae50bd481872b4bff 91 PANTHER PTHR36965:SF1 2 91 9.6E-47 T 22-04-2016 TOLA_RS04925 8a15c42be1f322aae50bd481872b4bff 91 PANTHER PTHR36965 2 91 9.6E-47 T 22-04-2016 TOLA_RS04925 8a15c42be1f322aae50bd481872b4bff 91 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 76 3.0E-29 T 22-04-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 TOLA_RS09765 55e78054074f8e8f6862bf0090bd6aff 220 SUPERFAMILY SSF52172 1 171 3.13E-36 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS09765 55e78054074f8e8f6862bf0090bd6aff 220 SMART SM00448 1 111 1.7E-39 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS09765 55e78054074f8e8f6862bf0090bd6aff 220 Pfam PF00072 Response regulator receiver domain 3 111 1.6E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS09765 55e78054074f8e8f6862bf0090bd6aff 220 SMART SM00862 144 215 3.7E-21 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS09765 55e78054074f8e8f6862bf0090bd6aff 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 215 4.3E-20 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS09765 55e78054074f8e8f6862bf0090bd6aff 220 PANTHER PTHR26402 1 217 1.4E-97 T 22-04-2016 TOLA_RS09765 55e78054074f8e8f6862bf0090bd6aff 220 Gene3D G3DSA:1.10.10.10 121 217 2.0E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09765 55e78054074f8e8f6862bf0090bd6aff 220 PANTHER PTHR26402:SF595 1 217 1.4E-97 T 22-04-2016 TOLA_RS09765 55e78054074f8e8f6862bf0090bd6aff 220 Gene3D G3DSA:3.40.50.2300 1 119 2.7E-35 T 22-04-2016 TOLA_RS08665 c43c4f70c1c00492055c56402af646f7 261 PANTHER PTHR21091:SF16 2 241 1.7E-79 T 22-04-2016 TOLA_RS08665 c43c4f70c1c00492055c56402af646f7 261 Gene3D G3DSA:3.40.1010.10 2 119 2.1E-43 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 TOLA_RS08665 c43c4f70c1c00492055c56402af646f7 261 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 84 117 - T 22-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS08665 c43c4f70c1c00492055c56402af646f7 261 SUPERFAMILY SSF53790 2 238 1.19E-75 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS08665 c43c4f70c1c00492055c56402af646f7 261 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 9 23 - T 22-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS08665 c43c4f70c1c00492055c56402af646f7 261 Gene3D G3DSA:3.30.950.10 120 245 4.1E-48 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 TOLA_RS08665 c43c4f70c1c00492055c56402af646f7 261 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 215 3.4E-44 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS08665 c43c4f70c1c00492055c56402af646f7 261 PANTHER PTHR21091 2 241 1.7E-79 T 22-04-2016 TOLA_RS08665 c43c4f70c1c00492055c56402af646f7 261 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 239 8.9E-94 T 22-04-2016 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS09305 f6e2942cce22ac258e12f45afe148ac5 276 PANTHER PTHR11624 7 276 4.0E-86 T 22-04-2016 IPR033247 Transketolase family TOLA_RS09305 f6e2942cce22ac258e12f45afe148ac5 276 Gene3D G3DSA:3.40.50.970 3 274 8.6E-85 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS09305 f6e2942cce22ac258e12f45afe148ac5 276 PANTHER PTHR11624:SF86 7 276 4.0E-86 T 22-04-2016 TOLA_RS09305 f6e2942cce22ac258e12f45afe148ac5 276 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 20 269 6.3E-41 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS09305 f6e2942cce22ac258e12f45afe148ac5 276 SUPERFAMILY SSF52518 3 274 1.58E-76 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS00555 ea89670414cb568a03f2c8dfd66a82cb 137 PANTHER PTHR12220 1 137 5.3E-74 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 TOLA_RS00555 ea89670414cb568a03f2c8dfd66a82cb 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.6E-40 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 TOLA_RS00555 ea89670414cb568a03f2c8dfd66a82cb 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.6E-40 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 TOLA_RS00555 ea89670414cb568a03f2c8dfd66a82cb 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.6E-40 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 TOLA_RS00555 ea89670414cb568a03f2c8dfd66a82cb 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.6E-40 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 TOLA_RS00555 ea89670414cb568a03f2c8dfd66a82cb 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 7.9E-59 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 TOLA_RS00555 ea89670414cb568a03f2c8dfd66a82cb 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.8E-46 T 22-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00555 ea89670414cb568a03f2c8dfd66a82cb 137 SUPERFAMILY SSF54686 1 135 1.96E-54 T 22-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00555 ea89670414cb568a03f2c8dfd66a82cb 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 22-04-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00555 ea89670414cb568a03f2c8dfd66a82cb 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.741 T 22-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 TOLA_RS00555 ea89670414cb568a03f2c8dfd66a82cb 137 Gene3D G3DSA:3.90.1170.10 24 135 2.8E-52 T 22-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00555 ea89670414cb568a03f2c8dfd66a82cb 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 22-04-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS02465 afad1639c15890cdfe6b846708feddc1 218 SUPERFAMILY SSF51182 106 194 3.27E-14 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS02465 afad1639c15890cdfe6b846708feddc1 218 Gene3D G3DSA:2.60.120.10 109 203 8.0E-15 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS02465 afad1639c15890cdfe6b846708feddc1 218 Pfam PF12973 ChrR Cupin-like domain 111 193 2.9E-15 T 22-04-2016 IPR025979 ChrR-like cupin domain TOLA_RS02465 afad1639c15890cdfe6b846708feddc1 218 TIGRFAM TIGR02451 anti_sig_ChrR: anti-sigma factor, putative, ChrR family 5 215 2.7E-55 T 22-04-2016 IPR012807 Anti-sigma factor ChrR, putative TOLA_RS01705 f92a8dbf4c5c37ebd9fe44fd64b78118 269 Pfam PF02673 Bacitracin resistance protein BacA 8 255 1.5E-76 T 22-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TOLA_RS01705 f92a8dbf4c5c37ebd9fe44fd64b78118 269 PANTHER PTHR30622 1 268 1.3E-115 T 22-04-2016 TOLA_RS01705 f92a8dbf4c5c37ebd9fe44fd64b78118 269 PANTHER PTHR30622:SF3 1 268 1.3E-115 T 22-04-2016 TOLA_RS01705 f92a8dbf4c5c37ebd9fe44fd64b78118 269 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 260 17.335 T 22-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TOLA_RS01705 f92a8dbf4c5c37ebd9fe44fd64b78118 269 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 8 253 1.5E-69 T 22-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TOLA_RS12905 60d29e05bd1f92ba7ab1e5fcdbca9dc0 540 PANTHER PTHR30443 21 534 2.0E-179 T 22-04-2016 TOLA_RS12905 60d29e05bd1f92ba7ab1e5fcdbca9dc0 540 SUPERFAMILY SSF53649 224 491 2.06E-22 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 TOLA_RS12905 60d29e05bd1f92ba7ab1e5fcdbca9dc0 540 PANTHER PTHR30443:SF4 21 534 2.0E-179 T 22-04-2016 TOLA_RS12905 60d29e05bd1f92ba7ab1e5fcdbca9dc0 540 Gene3D G3DSA:3.40.720.10 224 489 5.6E-15 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 TOLA_RS12905 60d29e05bd1f92ba7ab1e5fcdbca9dc0 540 Pfam PF00884 Sulfatase 223 487 5.0E-39 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 TOLA_RS09405 68f8f5225d86f92142f54de3661e9a03 388 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 7 383 1.1E-136 T 22-04-2016 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 TOLA_RS09405 68f8f5225d86f92142f54de3661e9a03 388 Pfam PF00155 Aminotransferase class I and II 37 382 1.1E-44 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TOLA_RS09405 68f8f5225d86f92142f54de3661e9a03 388 SUPERFAMILY SSF53383 6 383 1.21E-96 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS09405 68f8f5225d86f92142f54de3661e9a03 388 PANTHER PTHR11751 6 383 1.0E-170 T 22-04-2016 TOLA_RS09405 68f8f5225d86f92142f54de3661e9a03 388 Gene3D G3DSA:3.90.1150.10 254 385 5.5E-36 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS09405 68f8f5225d86f92142f54de3661e9a03 388 Gene3D G3DSA:3.40.640.10 43 253 5.5E-55 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS09405 68f8f5225d86f92142f54de3661e9a03 388 PANTHER PTHR11751:SF422 6 383 1.0E-170 T 22-04-2016 TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 31 214 1.6E-53 T 22-04-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 PANTHER PTHR11807:SF2 25 438 2.1E-83 T 22-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 Pfam PF01171 PP-loop family 32 210 7.4E-57 T 22-04-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 Pfam PF11734 TilS substrate C-terminal domain 378 451 2.1E-24 T 22-04-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 PANTHER PTHR11807 25 438 2.1E-83 T 22-04-2016 TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 SMART SM00977 377 451 8.1E-23 T 22-04-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 Pfam PF09179 TilS substrate binding domain 259 326 6.7E-19 T 22-04-2016 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 SUPERFAMILY SSF82829 247 330 1.96E-24 T 22-04-2016 TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 SUPERFAMILY SSF56037 340 454 1.44E-28 T 22-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 388 424 7.7E-13 T 22-04-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 Gene3D G3DSA:3.40.50.620 30 190 7.8E-11 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 SUPERFAMILY SSF52402 24 243 1.95E-57 T 22-04-2016 TOLA_RS04230 97beef79271366805dc9b0cb7dc39362 455 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 23 320 24.21 T 22-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 SUPERFAMILY SSF54211 616 793 3.34E-47 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 Gene3D G3DSA:3.30.230.10 614 793 1.1E-66 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 TIGRFAM TIGR00763 lon: endopeptidase La 31 793 1.1E-281 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 PANTHER PTHR10046 2 795 0.0 T 22-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 593 792 4.5E-75 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 Gene3D G3DSA:3.40.50.300 336 512 1.5E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 SUPERFAMILY SSF88697 29 223 2.73E-18 T 22-04-2016 IPR015947 PUA-like domain TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 SUPERFAMILY SSF52540 335 610 8.79E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 PIRSF PIRSF001174 13 796 6.9E-275 T 22-04-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 379 398 2.2E-47 T 22-04-2016 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 748 766 2.2E-47 T 22-04-2016 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 695 714 2.2E-47 T 22-04-2016 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 616 632 2.2E-47 T 22-04-2016 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 725 744 2.2E-47 T 22-04-2016 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 Hamap MF_01973 Lon protease [lon]. 29 794 58.319 T 22-04-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 375 513 1.4E-23 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 29 224 5.7E-27 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 698 706 - T 22-04-2016 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 SMART SM00464 28 224 2.9E-28 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 Gene3D G3DSA:1.10.8.60 515 607 1.4E-29 T 22-04-2016 TOLA_RS05380 6dad4a5e3e17f665bd9f905e8b245ebc 796 SMART SM00382 371 519 2.1E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS05270 83f2c9f2c2ff8783b860d1ee4100c6bf 204 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 3 106 1.7E-22 T 22-04-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 TOLA_RS05270 83f2c9f2c2ff8783b860d1ee4100c6bf 204 SUPERFAMILY SSF54534 5 202 1.81E-53 T 22-04-2016 TOLA_RS05270 83f2c9f2c2ff8783b860d1ee4100c6bf 204 Gene3D G3DSA:3.10.50.40 92 202 7.2E-45 T 22-04-2016 TOLA_RS05270 83f2c9f2c2ff8783b860d1ee4100c6bf 204 PANTHER PTHR10516:SF320 84 202 8.1E-61 T 22-04-2016 TOLA_RS05270 83f2c9f2c2ff8783b860d1ee4100c6bf 204 PANTHER PTHR10516:SF320 19 42 8.1E-61 T 22-04-2016 TOLA_RS05270 83f2c9f2c2ff8783b860d1ee4100c6bf 204 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 114 200 4.4E-27 T 22-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 TOLA_RS05270 83f2c9f2c2ff8783b860d1ee4100c6bf 204 PANTHER PTHR10516 84 202 8.1E-61 T 22-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type TOLA_RS05270 83f2c9f2c2ff8783b860d1ee4100c6bf 204 PANTHER PTHR10516 19 42 8.1E-61 T 22-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type TOLA_RS05270 83f2c9f2c2ff8783b860d1ee4100c6bf 204 Gene3D G3DSA:1.10.287.460 3 91 6.1E-23 T 22-04-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 TOLA_RS02335 fe148b78091c77f6888534f4e66e4b55 300 Gene3D G3DSA:3.30.420.40 134 280 5.9E-46 T 22-04-2016 TOLA_RS02335 fe148b78091c77f6888534f4e66e4b55 300 SUPERFAMILY SSF53067 1 298 4.95E-63 T 22-04-2016 TOLA_RS02335 fe148b78091c77f6888534f4e66e4b55 300 ProSitePatterns PS01125 ROK family signature. 131 158 - T 22-04-2016 IPR000600 ROK family TOLA_RS02335 fe148b78091c77f6888534f4e66e4b55 300 PANTHER PTHR18964:SF134 1 297 1.0E-106 T 22-04-2016 TOLA_RS02335 fe148b78091c77f6888534f4e66e4b55 300 Gene3D G3DSA:3.30.420.40 2 133 5.4E-40 T 22-04-2016 TOLA_RS02335 fe148b78091c77f6888534f4e66e4b55 300 Pfam PF00480 ROK family 4 297 2.4E-80 T 22-04-2016 IPR000600 ROK family TOLA_RS02335 fe148b78091c77f6888534f4e66e4b55 300 PANTHER PTHR18964 1 297 1.0E-106 T 22-04-2016 TOLA_RS04550 93061421c353ef3516203a9a8c09664c 343 Pfam PF13413 Helix-turn-helix domain 18 78 8.6E-20 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS04550 93061421c353ef3516203a9a8c09664c 343 SMART SM00530 17 78 9.2E-5 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS04550 93061421c353ef3516203a9a8c09664c 343 SUPERFAMILY SSF47413 13 68 9.57E-8 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS04550 93061421c353ef3516203a9a8c09664c 343 PANTHER PTHR34475:SF1 1 336 9.9E-44 T 22-04-2016 TOLA_RS04550 93061421c353ef3516203a9a8c09664c 343 PANTHER PTHR34475 1 336 9.9E-44 T 22-04-2016 TOLA_RS04550 93061421c353ef3516203a9a8c09664c 343 Pfam PF13464 Domain of unknown function (DUF4115) 265 339 1.4E-23 T 22-04-2016 IPR025194 Domain of unknown function DUF4115 TOLA_RS04550 93061421c353ef3516203a9a8c09664c 343 Gene3D G3DSA:1.10.260.40 3 78 4.7E-9 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS05890 449b530375b852024603a9263d822aad 357 Pfam PF13533 Biotin-lipoyl like 70 118 3.4E-14 T 22-04-2016 TOLA_RS05890 449b530375b852024603a9263d822aad 357 Pfam PF13437 HlyD family secretion protein 226 328 1.4E-6 T 22-04-2016 TOLA_RS05890 449b530375b852024603a9263d822aad 357 PANTHER PTHR32347 17 342 4.3E-12 T 22-04-2016 TOLA_RS05890 449b530375b852024603a9263d822aad 357 Gene3D G3DSA:2.40.50.100 71 101 1.6E-12 T 22-04-2016 TOLA_RS05890 449b530375b852024603a9263d822aad 357 Gene3D G3DSA:2.40.50.100 218 253 1.6E-12 T 22-04-2016 TOLA_RS05890 449b530375b852024603a9263d822aad 357 SUPERFAMILY SSF51230 214 255 8.01E-5 T 22-04-2016 IPR011053 Single hybrid motif TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 Gene3D G3DSA:2.70.210.12 2 156 1.4E-58 T 22-04-2016 IPR006169 GTP1/OBG domain GO:0005525 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 PIRSF PIRSF002401 1 378 1.3E-139 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 Pfam PF01926 50S ribosome-binding GTPase 162 284 4.9E-24 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 SUPERFAMILY SSF52540 153 336 7.65E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 Hamap MF_01454 GTPase Obg [obg]. 2 333 48.303 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 SUPERFAMILY SSF82051 2 156 1.83E-56 T 22-04-2016 IPR006169 GTP1/OBG domain GO:0005525 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 332 2.8E-147 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 22-04-2016 IPR006074 GTP1/OBG, conserved site GO:0005525 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 PANTHER PTHR11702 1 380 1.9E-188 T 22-04-2016 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 Gene3D G3DSA:3.40.50.300 157 338 1.2E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 Pfam PF01018 GTP1/OBG 3 156 1.1E-59 T 22-04-2016 IPR006169 GTP1/OBG domain GO:0005525 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 PANTHER PTHR11702:SF3 1 380 1.9E-188 T 22-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 1.6E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 1.6E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 1.6E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS12085 4d89bd0886d55ef8a4d639893057847c 393 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 1.6E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS12015 3a4852425d2bfab1e0acceb50028d42f 220 Pfam PF00849 RNA pseudouridylate synthase 22 168 8.4E-30 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS12015 3a4852425d2bfab1e0acceb50028d42f 220 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 217 2.3E-60 T 22-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS12015 3a4852425d2bfab1e0acceb50028d42f 220 PANTHER PTHR11079 6 217 2.4E-66 T 22-04-2016 TOLA_RS12015 3a4852425d2bfab1e0acceb50028d42f 220 SUPERFAMILY SSF55120 14 218 2.72E-65 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS12015 3a4852425d2bfab1e0acceb50028d42f 220 PANTHER PTHR11079:SF86 6 217 2.4E-66 T 22-04-2016 TOLA_RS12015 3a4852425d2bfab1e0acceb50028d42f 220 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 60 74 - T 22-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS06115 9d0e7dbf034a3b04f7e7d30996694ad7 231 PANTHER PTHR26402:SF399 6 228 2.6E-91 T 22-04-2016 TOLA_RS06115 9d0e7dbf034a3b04f7e7d30996694ad7 231 SMART SM00862 152 228 1.7E-20 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS06115 9d0e7dbf034a3b04f7e7d30996694ad7 231 Pfam PF00072 Response regulator receiver domain 8 117 8.2E-27 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS06115 9d0e7dbf034a3b04f7e7d30996694ad7 231 PANTHER PTHR26402 6 228 2.6E-91 T 22-04-2016 TOLA_RS06115 9d0e7dbf034a3b04f7e7d30996694ad7 231 SMART SM00448 6 116 3.1E-37 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS06115 9d0e7dbf034a3b04f7e7d30996694ad7 231 Gene3D G3DSA:1.10.10.10 130 229 4.4E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06115 9d0e7dbf034a3b04f7e7d30996694ad7 231 Gene3D G3DSA:3.40.50.2300 5 129 7.8E-37 T 22-04-2016 TOLA_RS06115 9d0e7dbf034a3b04f7e7d30996694ad7 231 SUPERFAMILY SSF52172 7 178 6.04E-38 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS06115 9d0e7dbf034a3b04f7e7d30996694ad7 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 8.7E-21 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS02870 b31183b466ad62d31ddb6dcceb66b586 185 Pfam PF04264 YceI-like domain 25 182 3.0E-28 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TOLA_RS02870 b31183b466ad62d31ddb6dcceb66b586 185 PANTHER PTHR34406:SF1 1 185 3.6E-28 T 22-04-2016 TOLA_RS02870 b31183b466ad62d31ddb6dcceb66b586 185 SUPERFAMILY SSF101874 25 185 4.45E-38 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TOLA_RS02870 b31183b466ad62d31ddb6dcceb66b586 185 PANTHER PTHR34406 1 185 3.6E-28 T 22-04-2016 TOLA_RS02870 b31183b466ad62d31ddb6dcceb66b586 185 SMART SM00867 23 183 1.3E-38 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TOLA_RS02870 b31183b466ad62d31ddb6dcceb66b586 185 Gene3D G3DSA:2.40.128.110 25 185 4.6E-38 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TOLA_RS14225 3469f41b7cca0e85e3deb8177194adf6 90 Gene3D G3DSA:3.40.1260.10 1 85 7.6E-25 T 22-04-2016 IPR027396 DsrEFH-like TOLA_RS14225 3469f41b7cca0e85e3deb8177194adf6 90 Pfam PF04077 DsrH like protein 8 84 8.2E-21 T 22-04-2016 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 TOLA_RS14225 3469f41b7cca0e85e3deb8177194adf6 90 SUPERFAMILY SSF75169 1 90 5.21E-22 T 22-04-2016 IPR027396 DsrEFH-like TOLA_RS14225 3469f41b7cca0e85e3deb8177194adf6 90 TIGRFAM TIGR03011 sulf_tusB_dsrH: sulfur relay protein TusB/DsrH 2 90 1.3E-22 T 22-04-2016 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 TOLA_RS14225 3469f41b7cca0e85e3deb8177194adf6 90 PANTHER PTHR37526 1 90 1.5E-15 T 22-04-2016 TOLA_RS01190 32263df1f81b937c8a1f0087275893bf 378 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 62 171 1.1E-27 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TOLA_RS01190 32263df1f81b937c8a1f0087275893bf 378 PANTHER PTHR11695:SF523 47 359 3.1E-161 T 22-04-2016 TOLA_RS01190 32263df1f81b937c8a1f0087275893bf 378 SUPERFAMILY SSF50129 40 208 1.73E-37 T 22-04-2016 IPR011032 GroES-like TOLA_RS01190 32263df1f81b937c8a1f0087275893bf 378 Pfam PF00107 Zinc-binding dehydrogenase 212 335 2.8E-23 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TOLA_RS01190 32263df1f81b937c8a1f0087275893bf 378 Gene3D G3DSA:3.40.50.720 204 322 2.2E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01190 32263df1f81b937c8a1f0087275893bf 378 Gene3D G3DSA:3.90.180.10 36 203 7.1E-39 T 22-04-2016 IPR011032 GroES-like TOLA_RS01190 32263df1f81b937c8a1f0087275893bf 378 SUPERFAMILY SSF51735 177 330 4.55E-29 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01190 32263df1f81b937c8a1f0087275893bf 378 PANTHER PTHR11695 47 359 3.1E-161 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 TOLA_RS07015 3d43f248b278af7a4c42262ddfe2fe07 368 PANTHER PTHR32196 1 342 2.1E-86 T 22-04-2016 TOLA_RS07015 3d43f248b278af7a4c42262ddfe2fe07 368 PANTHER PTHR32196:SF30 1 342 2.1E-86 T 22-04-2016 TOLA_RS07015 3d43f248b278af7a4c42262ddfe2fe07 368 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 342 9.1E-35 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS15510 c8c4e76f0b2c4c53ade2174fc49f85bc 185 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 5 154 8.7E-38 T 22-04-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA TOLA_RS15510 c8c4e76f0b2c4c53ade2174fc49f85bc 185 PANTHER PTHR23133:SF3 1 183 2.0E-65 T 22-04-2016 TOLA_RS15510 c8c4e76f0b2c4c53ade2174fc49f85bc 185 SUPERFAMILY SSF56784 5 178 8.0E-51 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS15510 c8c4e76f0b2c4c53ade2174fc49f85bc 185 TIGRFAM TIGR00213 GmhB_yaeD: D,D-heptose 1,7-bisphosphate phosphatase 5 176 7.1E-79 T 22-04-2016 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 TOLA_RS15510 c8c4e76f0b2c4c53ade2174fc49f85bc 185 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 5 153 3.3E-42 T 22-04-2016 IPR006543 Histidinol-phosphate phosphatase GO:0016791 TOLA_RS15510 c8c4e76f0b2c4c53ade2174fc49f85bc 185 PIRSF PIRSF004682 1 185 1.5E-68 T 22-04-2016 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 TOLA_RS15510 c8c4e76f0b2c4c53ade2174fc49f85bc 185 Pfam PF13242 HAD-hyrolase-like 107 169 6.5E-14 T 22-04-2016 TOLA_RS15510 c8c4e76f0b2c4c53ade2174fc49f85bc 185 PANTHER PTHR23133 1 183 2.0E-65 T 22-04-2016 TOLA_RS15510 c8c4e76f0b2c4c53ade2174fc49f85bc 185 Gene3D G3DSA:3.40.50.1000 5 178 2.4E-62 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS04580 b5cdc97b74aee6a2368eb56117ecc3f0 76 Gene3D G3DSA:2.10.290.10 4 73 1.0E-24 T 22-04-2016 IPR029037 YfgJ-like TOLA_RS04580 b5cdc97b74aee6a2368eb56117ecc3f0 76 ProDom PD060428 YFGJ CYTOPLASMIC VP0614 ECS3372 VC0765 YPO2873 Y1359 STY2763A VV0773 7 71 2.0E-10 T 22-04-2016 IPR010807 Protein of unknown function DUF1407 TOLA_RS04580 b5cdc97b74aee6a2368eb56117ecc3f0 76 Pfam PF07191 zinc-ribbons 6 71 1.7E-23 T 22-04-2016 IPR010807 Protein of unknown function DUF1407 TOLA_RS04580 b5cdc97b74aee6a2368eb56117ecc3f0 76 SUPERFAMILY SSF161187 4 72 9.55E-24 T 22-04-2016 IPR029037 YfgJ-like TOLA_RS10425 9a9211903fbd3b589059a046a5bc6a65 155 PANTHER PTHR22769 17 151 4.6E-53 T 22-04-2016 TOLA_RS10425 9a9211903fbd3b589059a046a5bc6a65 155 SUPERFAMILY SSF55811 9 149 9.75E-29 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS10425 9a9211903fbd3b589059a046a5bc6a65 155 Gene3D G3DSA:3.90.79.10 14 148 5.6E-32 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS10425 9a9211903fbd3b589059a046a5bc6a65 155 PIRSF PIRSF037599 3 155 1.2E-67 T 22-04-2016 IPR028613 GDP-mannose mannosyl hydrolase Gmm GO:0000287|GO:0008727 TOLA_RS10425 9a9211903fbd3b589059a046a5bc6a65 155 PANTHER PTHR22769:SF31 17 151 4.6E-53 T 22-04-2016 TOLA_RS10425 9a9211903fbd3b589059a046a5bc6a65 155 Pfam PF00293 NUDIX domain 20 145 2.1E-19 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TOLA_RS10425 9a9211903fbd3b589059a046a5bc6a65 155 ProSitePatterns PS00893 Nudix box signature. 52 73 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 SUPERFAMILY SSF53850 2 216 3.72E-84 T 22-04-2016 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 6.4E-51 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 6.4E-51 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 6.4E-51 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 PRINTS PR00151 Porphobilinogen deaminase signature 228 245 6.4E-51 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 6.4E-51 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 Gene3D G3DSA:3.40.190.10 2 108 3.9E-47 T 22-04-2016 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 Gene3D G3DSA:3.30.160.40 219 303 1.8E-27 T 22-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 296 1.7E-112 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 Gene3D G3DSA:3.40.190.10 109 197 6.6E-38 T 22-04-2016 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 210 3.3E-78 T 22-04-2016 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 224 294 1.7E-23 T 22-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 PIRSF PIRSF001438 1 308 3.7E-120 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 PANTHER PTHR11557 1 306 5.4E-160 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 296 39.207 T 22-04-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 229 245 - T 22-04-2016 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16045 40f9e44c4d6ecce6f9871144cb632f76 308 SUPERFAMILY SSF54782 219 306 1.44E-27 T 22-04-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS02760 edc8bcbcb08782c1d6e1ac8c69b42809 72 Gene3D G3DSA:3.30.50.10 3 56 2.2E-23 T 22-04-2016 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 TOLA_RS02760 edc8bcbcb08782c1d6e1ac8c69b42809 72 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 1 58 18.911 T 22-04-2016 IPR005584 DNA gyrase inhibitor YacG GO:0008270 TOLA_RS02760 edc8bcbcb08782c1d6e1ac8c69b42809 72 PANTHER PTHR36150 1 49 2.6E-20 T 22-04-2016 TOLA_RS02760 edc8bcbcb08782c1d6e1ac8c69b42809 72 Pfam PF03884 Domain of unknown function (DUF329) 5 53 1.3E-23 T 22-04-2016 IPR005584 DNA gyrase inhibitor YacG GO:0008270 TOLA_RS02760 edc8bcbcb08782c1d6e1ac8c69b42809 72 SUPERFAMILY SSF57716 2 56 2.71E-19 T 22-04-2016 TOLA_RS02760 edc8bcbcb08782c1d6e1ac8c69b42809 72 PANTHER PTHR36150:SF1 1 49 2.6E-20 T 22-04-2016 TOLA_RS12400 55bfea08e2445010a03fe4248693a9f8 77 Pfam PF11660 Protein of unknown function (DUF3262) 1 76 1.1E-25 T 22-04-2016 IPR021676 Protein of unknown function DUF3262 TOLA_RS12400 55bfea08e2445010a03fe4248693a9f8 77 TIGRFAM TIGR03758 conj_TIGR03758: integrating conjugative element protein, PFL_4701 family 2 77 7.6E-32 T 22-04-2016 IPR021676 Protein of unknown function DUF3262 TOLA_RS11120 6df742ba448a3ead0bd5f94da1e8c028 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 156 172 - T 22-04-2016 IPR018201 Beta-ketoacyl synthase, active site TOLA_RS11120 6df742ba448a3ead0bd5f94da1e8c028 413 Gene3D G3DSA:3.40.47.10 264 412 1.2E-64 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS11120 6df742ba448a3ead0bd5f94da1e8c028 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 256 370 4.2E-40 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal TOLA_RS11120 6df742ba448a3ead0bd5f94da1e8c028 413 PANTHER PTHR11712 3 412 1.8E-218 T 22-04-2016 TOLA_RS11120 6df742ba448a3ead0bd5f94da1e8c028 413 SMART SM00825 Beta-ketoacyl synthase 6 413 1.9E-18 T 22-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TOLA_RS11120 6df742ba448a3ead0bd5f94da1e8c028 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 248 1.2E-66 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal TOLA_RS11120 6df742ba448a3ead0bd5f94da1e8c028 413 PIRSF PIRSF000447 1 413 3.4E-195 T 22-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 TOLA_RS11120 6df742ba448a3ead0bd5f94da1e8c028 413 SUPERFAMILY SSF53901 216 412 5.07E-74 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS11120 6df742ba448a3ead0bd5f94da1e8c028 413 SUPERFAMILY SSF53901 3 253 1.83E-81 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS11120 6df742ba448a3ead0bd5f94da1e8c028 413 Gene3D G3DSA:3.40.47.10 2 261 2.4E-81 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS11120 6df742ba448a3ead0bd5f94da1e8c028 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 411 1.1E-198 T 22-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 TOLA_RS11820 3c324e4fec77af4815b1ec95abc6cd9a 369 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 7 362 40.533 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 TOLA_RS11820 3c324e4fec77af4815b1ec95abc6cd9a 369 Pfam PF03054 tRNA methyl transferase 8 361 1.8E-144 T 22-04-2016 TOLA_RS11820 3c324e4fec77af4815b1ec95abc6cd9a 369 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 8 361 6.2E-155 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 TOLA_RS11820 3c324e4fec77af4815b1ec95abc6cd9a 369 PANTHER PTHR11933 1 365 2.6E-217 T 22-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 TOLA_RS11820 3c324e4fec77af4815b1ec95abc6cd9a 369 PANTHER PTHR11933:SF10 1 365 2.6E-217 T 22-04-2016 TOLA_RS11820 3c324e4fec77af4815b1ec95abc6cd9a 369 SUPERFAMILY SSF52402 8 295 9.7E-56 T 22-04-2016 TOLA_RS11820 3c324e4fec77af4815b1ec95abc6cd9a 369 Gene3D G3DSA:3.40.50.620 3 212 5.4E-98 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS11820 3c324e4fec77af4815b1ec95abc6cd9a 369 Gene3D G3DSA:2.40.30.10 283 364 2.4E-31 T 22-04-2016 TOLA_RS11820 3c324e4fec77af4815b1ec95abc6cd9a 369 Gene3D G3DSA:2.30.30.280 214 281 2.2E-34 T 22-04-2016 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 TOLA_RS02055 4272c8f19d55a04a44e8dd9c5620e02c 213 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 15 200 6.3E-61 T 22-04-2016 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 TOLA_RS02055 4272c8f19d55a04a44e8dd9c5620e02c 213 Pfam PF00293 NUDIX domain 59 180 8.0E-10 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TOLA_RS02055 4272c8f19d55a04a44e8dd9c5620e02c 213 SUPERFAMILY SSF55811 7 207 2.3E-46 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS02055 4272c8f19d55a04a44e8dd9c5620e02c 213 PANTHER PTHR11839:SF5 10 209 2.8E-99 T 22-04-2016 TOLA_RS02055 4272c8f19d55a04a44e8dd9c5620e02c 213 PANTHER PTHR11839 10 209 2.8E-99 T 22-04-2016 TOLA_RS02055 4272c8f19d55a04a44e8dd9c5620e02c 213 ProSitePatterns PS00893 Nudix box signature. 98 119 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TOLA_RS02055 4272c8f19d55a04a44e8dd9c5620e02c 213 Gene3D G3DSA:3.90.79.10 16 202 2.1E-53 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 SMART SM00382 345 516 2.0E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 SMART SM00382 28 231 3.4E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 Gene3D G3DSA:3.40.50.300 7 102 2.0E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 Gene3D G3DSA:3.40.50.300 137 283 2.0E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 Gene3D G3DSA:3.40.50.300 321 545 3.7E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 SUPERFAMILY SSF52540 11 232 3.58E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 Pfam PF16326 ABC transporter C-terminal domain 566 635 9.2E-19 T 22-04-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 Pfam PF00005 ABC transporter 337 470 7.8E-24 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 Pfam PF00005 ABC transporter 19 186 5.8E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 PANTHER PTHR19211 1 576 1.9E-232 T 22-04-2016 TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 PANTHER PTHR19211:SF45 1 576 1.9E-232 T 22-04-2016 TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 Pfam PF12848 ABC transporter 225 297 1.2E-9 T 22-04-2016 IPR032781 ABC-transporter extension domain TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 SUPERFAMILY SSF52540 326 514 5.24E-44 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS07255 eae9551178dbe5ba2f0e494ad2bd775b 640 ProSitePatterns PS00211 ABC transporters family signature. 442 456 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS12380 6b92c1a1771273f819323acf24186e85 729 Pfam PF12696 TraM recognition site of TraD and TraG 509 636 5.3E-11 T 22-04-2016 IPR032689 TraD/TraG, TraM recognition site TOLA_RS12380 6b92c1a1771273f819323acf24186e85 729 SUPERFAMILY SSF52540 149 314 5.84E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12380 6b92c1a1771273f819323acf24186e85 729 SUPERFAMILY SSF52540 399 657 5.84E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12380 6b92c1a1771273f819323acf24186e85 729 Gene3D G3DSA:3.40.50.300 445 661 1.6E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12380 6b92c1a1771273f819323acf24186e85 729 Gene3D G3DSA:3.40.50.300 167 268 1.6E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12380 6b92c1a1771273f819323acf24186e85 729 TIGRFAM TIGR03743 SXT_TraD: conjugative coupling factor TraD, SXT/TOL subfamily 7 657 4.8E-264 T 22-04-2016 IPR022458 Conjugative coupling factor TraG/TraD TOLA_RS12380 6b92c1a1771273f819323acf24186e85 729 TIGRFAM TIGR03754 conj_TOL_TraD: conjugative coupling factor TraD, PFGI-1 class 7 657 0.0 T 22-04-2016 IPR022503 Conjugative coupling factor TraG/TraD, PFGI-1 TOLA_RS10205 c954edaf901cad1f8c5d7f74d65c00bd 201 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 33 201 5.5E-60 T 22-04-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 TOLA_RS10205 c954edaf901cad1f8c5d7f74d65c00bd 201 PIRSF PIRSF015617 6 201 5.6E-66 T 22-04-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 TOLA_RS10205 c954edaf901cad1f8c5d7f74d65c00bd 201 Gene3D G3DSA:3.40.50.300 8 201 4.6E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10205 c954edaf901cad1f8c5d7f74d65c00bd 201 SUPERFAMILY SSF52540 12 201 1.73E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10205 c954edaf901cad1f8c5d7f74d65c00bd 201 Pfam PF12557 Cob(I)alamin adenosyltransferase N terminal 1 26 3.0E-8 T 22-04-2016 IPR025826 Cob(I)alamin adenosyltransferase N-terminal domain KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 TOLA_RS10205 c954edaf901cad1f8c5d7f74d65c00bd 201 PANTHER PTHR30069 7 201 8.1E-68 T 22-04-2016 TOLA_RS10205 c954edaf901cad1f8c5d7f74d65c00bd 201 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 29 201 3.6E-73 T 22-04-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 TOLA_RS03520 29599160c8c015f7c272b1d4015f0776 340 SMART SM00849 59 227 0.0057 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS03520 29599160c8c015f7c272b1d4015f0776 340 SUPERFAMILY SSF56281 50 285 1.4E-23 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS03520 29599160c8c015f7c272b1d4015f0776 340 Gene3D G3DSA:3.60.15.10 44 311 1.3E-26 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS03520 29599160c8c015f7c272b1d4015f0776 340 Pfam PF12706 Beta-lactamase superfamily domain 105 282 1.4E-9 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 PIRSF PIRSF000157 2 934 0.0 T 22-04-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 SMART SM00861 593 786 1.1E-63 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 Pfam PF02779 Transketolase, pyrimidine binding domain 593 787 2.0E-64 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 790 932 1.4E-52 T 22-04-2016 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 SUPERFAMILY SSF52518 120 536 2.35E-81 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 Gene3D G3DSA:3.40.50.970 593 789 4.6E-26 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 19 51 5.9E-12 T 22-04-2016 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 Pfam PF00676 Dehydrogenase E1 component 219 514 2.0E-50 T 22-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 PANTHER PTHR23152:SF4 12 935 0.0 T 22-04-2016 TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 Gene3D G3DSA:3.40.50.970 162 525 1.7E-72 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 PANTHER PTHR23152 12 935 0.0 T 22-04-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 19 931 0.0 T 22-04-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TOLA_RS11315 4d2ad0ac951f0e7644e394baf72e15ce 935 SUPERFAMILY SSF52518 576 792 3.28E-52 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS14305 368f3fc18a4f92d874cbd87840a64d35 315 Gene3D G3DSA:3.40.50.300 9 315 6.6E-111 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14305 368f3fc18a4f92d874cbd87840a64d35 315 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 89 242 1.0E-15 T 22-04-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 TOLA_RS14305 368f3fc18a4f92d874cbd87840a64d35 315 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 10 315 1.1E-156 T 22-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 TOLA_RS14305 368f3fc18a4f92d874cbd87840a64d35 315 PANTHER PTHR10285 1 261 1.7E-162 T 22-04-2016 TOLA_RS14305 368f3fc18a4f92d874cbd87840a64d35 315 PANTHER PTHR10285 277 315 1.7E-162 T 22-04-2016 TOLA_RS14305 368f3fc18a4f92d874cbd87840a64d35 315 SUPERFAMILY SSF52540 8 315 9.94E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14305 368f3fc18a4f92d874cbd87840a64d35 315 Hamap MF_00215 Pantothenate kinase [coaA]. 1 315 183.683 T 22-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 TOLA_RS14305 368f3fc18a4f92d874cbd87840a64d35 315 PANTHER PTHR10285:SF7 1 261 1.7E-162 T 22-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 TOLA_RS14305 368f3fc18a4f92d874cbd87840a64d35 315 PANTHER PTHR10285:SF7 277 315 1.7E-162 T 22-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 TOLA_RS14305 368f3fc18a4f92d874cbd87840a64d35 315 PIRSF PIRSF000545 1 315 4.6E-149 T 22-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 TOLA_RS05565 5264d3539916197bbbe3900583a91c43 638 SUPERFAMILY SSF109998 204 249 3.14E-31 T 22-04-2016 IPR027304 Trigger factor/SurA domain TOLA_RS05565 5264d3539916197bbbe3900583a91c43 638 SUPERFAMILY SSF109998 43 170 3.14E-31 T 22-04-2016 IPR027304 Trigger factor/SurA domain TOLA_RS05565 5264d3539916197bbbe3900583a91c43 638 PANTHER PTHR10657 1 176 4.6E-113 T 22-04-2016 TOLA_RS05565 5264d3539916197bbbe3900583a91c43 638 PANTHER PTHR10657 204 523 4.6E-113 T 22-04-2016 TOLA_RS05565 5264d3539916197bbbe3900583a91c43 638 Pfam PF13624 SurA N-terminal domain 3 165 1.0E-42 T 22-04-2016 TOLA_RS05565 5264d3539916197bbbe3900583a91c43 638 SUPERFAMILY SSF54534 266 369 2.88E-28 T 22-04-2016 TOLA_RS05565 5264d3539916197bbbe3900583a91c43 638 PANTHER PTHR10657:SF13 1 176 4.6E-113 T 22-04-2016 TOLA_RS05565 5264d3539916197bbbe3900583a91c43 638 PANTHER PTHR10657:SF13 204 523 4.6E-113 T 22-04-2016 TOLA_RS05565 5264d3539916197bbbe3900583a91c43 638 Gene3D G3DSA:3.10.50.40 262 391 2.6E-39 T 22-04-2016 TOLA_RS05565 5264d3539916197bbbe3900583a91c43 638 Pfam PF13616 PPIC-type PPIASE domain 268 367 4.2E-31 T 22-04-2016 TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 Pfam PF00905 Penicillin binding protein transpeptidase domain 430 685 1.1E-18 T 22-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 Pfam PF00912 Transglycosylase 167 337 7.5E-56 T 22-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 Gene3D G3DSA:1.10.3810.10 168 338 7.2E-62 T 22-04-2016 TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 Gene3D G3DSA:3.30.2060.10 68 156 4.5E-28 T 22-04-2016 TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 Pfam PF14814 Bifunctional transglycosylase second domain 70 154 4.4E-28 T 22-04-2016 IPR028166 Bifunctional transglycosylase second domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00500+2.4.1.12|KEGG: 00550+3.4.-.-+2.4.1.129|KEGG: 00780+3.4.-.-|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 SUPERFAMILY SSF56601 319 341 6.76E-113 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 SUPERFAMILY SSF56601 370 756 6.76E-113 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 SUPERFAMILY SSF53955 166 358 2.7E-65 T 22-04-2016 IPR023346 Lysozyme-like domain TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 Gene3D G3DSA:1.20.5.100 18 52 2.3E-11 T 22-04-2016 TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 PANTHER PTHR32282 153 725 3.5E-227 T 22-04-2016 TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 PIRSF PIRSF002799 2 765 1.7E-297 T 22-04-2016 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00500+2.4.1.12|KEGG: 00550+3.4.-.-+2.4.1.129|KEGG: 00780+3.4.-.-|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 Gene3D G3DSA:3.40.710.10 339 733 8.7E-108 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 24 743 4.6E-276 T 22-04-2016 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00500+2.4.1.12|KEGG: 00550+3.4.-.-+2.4.1.129|KEGG: 00780+3.4.-.-|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS04055 aaf43f905d2c9a11b50fb5586d8704cc 767 PANTHER PTHR32282:SF11 153 725 3.5E-227 T 22-04-2016 TOLA_RS13805 2726fb40cf41898e14cdf1e2ca141197 145 PANTHER PTHR30558 1 144 1.4E-50 T 22-04-2016 TOLA_RS13805 2726fb40cf41898e14cdf1e2ca141197 145 TIGRFAM TIGR02801 tolR: protein TolR 12 139 6.5E-43 T 22-04-2016 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 TOLA_RS13805 2726fb40cf41898e14cdf1e2ca141197 145 Pfam PF02472 Biopolymer transport protein ExbD/TolR 9 139 3.1E-27 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 TOLA_RS13805 2726fb40cf41898e14cdf1e2ca141197 145 PANTHER PTHR30558:SF7 1 144 1.4E-50 T 22-04-2016 TOLA_RS01550 238b1d30e080c76f8c9f8421eb750153 383 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 24 366 9.6E-45 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 TOLA_RS01550 238b1d30e080c76f8c9f8421eb750153 383 Gene3D G3DSA:2.40.50.100 163 195 1.9E-18 T 22-04-2016 TOLA_RS01550 238b1d30e080c76f8c9f8421eb750153 383 Gene3D G3DSA:2.40.50.100 40 74 1.9E-18 T 22-04-2016 TOLA_RS01550 238b1d30e080c76f8c9f8421eb750153 383 PANTHER PTHR30572 16 350 7.9E-106 T 22-04-2016 TOLA_RS01550 238b1d30e080c76f8c9f8421eb750153 383 PANTHER PTHR30572:SF3 16 350 7.9E-106 T 22-04-2016 TOLA_RS01550 238b1d30e080c76f8c9f8421eb750153 383 SUPERFAMILY SSF111369 32 221 2.09E-23 T 22-04-2016 TOLA_RS01550 238b1d30e080c76f8c9f8421eb750153 383 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 35 246 2.2E-15 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TOLA_RS07615 6d7f4660fa4d9c08e8debda524f30317 494 PANTHER PTHR11814 7 488 9.6E-285 T 22-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 TOLA_RS07615 6d7f4660fa4d9c08e8debda524f30317 494 Pfam PF01740 STAS domain 403 485 1.0E-10 T 22-04-2016 IPR002645 STAS domain TOLA_RS07615 6d7f4660fa4d9c08e8debda524f30317 494 PANTHER PTHR11814:SF76 7 488 9.6E-285 T 22-04-2016 TOLA_RS07615 6d7f4660fa4d9c08e8debda524f30317 494 Pfam PF00916 Sulfate permease family 164 344 1.2E-28 T 22-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 TOLA_RS07615 6d7f4660fa4d9c08e8debda524f30317 494 Pfam PF00916 Sulfate permease family 14 143 2.9E-27 T 22-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 TOLA_RS07615 6d7f4660fa4d9c08e8debda524f30317 494 SUPERFAMILY SSF52091 400 483 2.35E-12 T 22-04-2016 IPR002645 STAS domain TOLA_RS07615 6d7f4660fa4d9c08e8debda524f30317 494 Gene3D G3DSA:3.30.750.24 402 482 5.1E-8 T 22-04-2016 IPR002645 STAS domain TOLA_RS02245 5c050e8884c132f2b66abe795a493b07 308 SUPERFAMILY SSF51604 100 294 1.13E-38 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS02245 5c050e8884c132f2b66abe795a493b07 308 Pfam PF13378 Enolase C-terminal domain-like 124 260 1.7E-15 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS02245 5c050e8884c132f2b66abe795a493b07 308 Gene3D G3DSA:3.20.20.120 128 283 9.5E-36 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS02245 5c050e8884c132f2b66abe795a493b07 308 SUPERFAMILY SSF54826 2 88 6.53E-17 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TOLA_RS02245 5c050e8884c132f2b66abe795a493b07 308 Gene3D G3DSA:3.30.390.10 2 127 2.8E-27 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TOLA_RS02245 5c050e8884c132f2b66abe795a493b07 308 SMART SM00922 107 201 4.7E-10 T 22-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TOLA_RS02245 5c050e8884c132f2b66abe795a493b07 308 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 153 184 - T 22-04-2016 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TOLA_RS02245 5c050e8884c132f2b66abe795a493b07 308 PANTHER PTHR13794 1 304 2.3E-40 T 22-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 TOLA_RS02245 5c050e8884c132f2b66abe795a493b07 308 PANTHER PTHR13794:SF8 1 304 2.3E-40 T 22-04-2016 IPR010197 o-succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00079|UniPathway: UPA01057 TOLA_RS02245 5c050e8884c132f2b66abe795a493b07 308 TIGRFAM TIGR01927 menC_gamma/gm+: o-succinylbenzoate synthase 6 287 3.2E-57 T 22-04-2016 TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 452 4.0E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 458 471 4.0E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 413 4.0E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 427 4.0E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 SUPERFAMILY SSF55874 322 472 2.1E-34 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 Pfam PF00672 HAMP domain 196 263 5.2E-12 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 PANTHER PTHR24423 209 472 3.2E-52 T 22-04-2016 TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 PANTHER PTHR24423 4 19 3.2E-52 T 22-04-2016 TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 Gene3D G3DSA:3.30.565.10 313 472 1.4E-35 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 SUPERFAMILY SSF47384 253 325 1.88E-12 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 Gene3D G3DSA:1.10.287.130 261 312 1.5E-13 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 SMART SM00388 268 326 2.2E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 471 5.1E-20 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 SMART SM00387 365 472 1.3E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 SMART SM00304 215 267 1.9E-6 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS15490 a241effe72f3c041683adf83e9867adc 472 Pfam PF00512 His Kinase A (phospho-acceptor) domain 269 324 1.8E-7 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS06230 c88a1bef7b3c8a1daef9883a80b0ebe6 724 Pfam PF12805 FUSC-like inner membrane protein yccS 69 341 6.9E-88 T 22-04-2016 IPR032692 Integral membrane protein YccS, N-terminal TOLA_RS06230 c88a1bef7b3c8a1daef9883a80b0ebe6 724 Pfam PF13515 Fusaric acid resistance protein-like 401 522 5.3E-21 T 22-04-2016 TOLA_RS06230 c88a1bef7b3c8a1daef9883a80b0ebe6 724 PANTHER PTHR30509:SF8 3 707 1.8E-150 T 22-04-2016 TOLA_RS06230 c88a1bef7b3c8a1daef9883a80b0ebe6 724 TIGRFAM TIGR01667 YCCS_YHJK: integral membrane protein, YccS/YhfK family 15 703 9.5E-163 T 22-04-2016 IPR010020 Integral membrane protein, YccS/YhfK TOLA_RS06230 c88a1bef7b3c8a1daef9883a80b0ebe6 724 TIGRFAM TIGR01666 YCCS: TIGR01666 family membrane protein 13 694 1.3E-155 T 22-04-2016 IPR010019 Integral membrane protein, YccS TOLA_RS06230 c88a1bef7b3c8a1daef9883a80b0ebe6 724 PANTHER PTHR30509 3 707 1.8E-150 T 22-04-2016 TOLA_RS15675 4f8e8fb7eb0260087600bf79050f95cf 324 PANTHER PTHR34351 15 324 3.4E-53 T 22-04-2016 TOLA_RS15675 4f8e8fb7eb0260087600bf79050f95cf 324 Pfam PF01882 Protein of unknown function DUF58 220 295 7.1E-11 T 22-04-2016 IPR002881 Domain of unknown function DUF58 TOLA_RS15675 4f8e8fb7eb0260087600bf79050f95cf 324 PANTHER PTHR34351:SF1 15 324 3.4E-53 T 22-04-2016 TOLA_RS01530 eafe2636a06625f98e7d816383d7597e 155 PANTHER PTHR30345 1 152 1.2E-50 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS01530 eafe2636a06625f98e7d816383d7597e 155 PIRSF PIRSF005384 1 150 8.1E-49 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS01530 eafe2636a06625f98e7d816383d7597e 155 Gene3D G3DSA:3.40.1400.10 1 152 8.1E-53 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS01530 eafe2636a06625f98e7d816383d7597e 155 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 148 4.8E-41 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS01530 eafe2636a06625f98e7d816383d7597e 155 SUPERFAMILY SSF89623 1 145 1.96E-46 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS01530 eafe2636a06625f98e7d816383d7597e 155 Pfam PF02502 Ribose/Galactose Isomerase 3 142 3.8E-44 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 Gene3D G3DSA:3.40.50.300 1340 1444 3.7E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 Gene3D G3DSA:3.40.50.300 1040 1176 3.7E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 SUPERFAMILY SSF56112 316 494 2.02E-12 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 SUPERFAMILY SSF56112 541 691 2.7E-17 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 SUPERFAMILY SSF52540 1165 1186 1.97E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 SUPERFAMILY SSF52540 1053 1123 1.97E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 SUPERFAMILY SSF52540 1300 1612 1.97E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 644 656 - T 22-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 Pfam PF08378 Nuclease-related domain 13 128 2.4E-12 T 22-04-2016 IPR011528 Nuclease-related domain, NERD TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 PANTHER PTHR10887 1395 1602 1.1E-69 T 22-04-2016 TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 PANTHER PTHR10887 1279 1379 1.1E-69 T 22-04-2016 TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 PANTHER PTHR10887 878 1148 1.1E-69 T 22-04-2016 TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 PANTHER PTHR10887 48 69 1.1E-69 T 22-04-2016 TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 Pfam PF13087 AAA domain 1401 1603 2.6E-44 T 22-04-2016 TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 Pfam PF00069 Protein kinase domain 548 663 3.0E-9 T 22-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 Gene3D G3DSA:1.10.510.10 599 669 6.2E-10 T 22-04-2016 TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 Pfam PF13086 AAA domain 1054 1378 2.0E-36 T 22-04-2016 TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 Gene3D G3DSA:1.10.510.10 317 434 1.5E-9 T 22-04-2016 TOLA_RS09795 07dd0d59fcc9559057b22a181497b70f 1656 Gene3D G3DSA:3.40.50.300 1503 1616 5.1E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09715 720440be770858cd26bce4621259ef7b 1065 Gene3D G3DSA:1.10.443.10 723 750 1.7E-18 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS09715 720440be770858cd26bce4621259ef7b 1065 Gene3D G3DSA:1.10.443.10 545 683 1.7E-18 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS09715 720440be770858cd26bce4621259ef7b 1065 Pfam PF00589 Phage integrase family 547 680 4.4E-10 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS09715 720440be770858cd26bce4621259ef7b 1065 SUPERFAMILY SSF56349 482 680 2.62E-16 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 179 315 1.8E-35 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 Pfam PF03454 MoeA C-terminal region (domain IV) 333 401 2.9E-14 T 22-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 255 288 - T 22-04-2016 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 UniPathway: UPA00344 TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 Gene3D G3DSA:2.40.340.10 334 399 9.5E-22 T 22-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 Pfam PF03453 MoeA N-terminal region (domain I and II) 10 169 8.1E-35 T 22-04-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 PANTHER PTHR10192 1 404 5.3E-189 T 22-04-2016 TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 Gene3D G3DSA:3.90.105.10 30 51 1.6E-18 T 22-04-2016 TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 Gene3D G3DSA:3.90.105.10 144 163 1.6E-18 T 22-04-2016 TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 SUPERFAMILY SSF63867 328 404 6.93E-20 T 22-04-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 SMART SM00852 182 319 5.1E-46 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 SUPERFAMILY SSF53218 179 323 7.98E-46 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 Pfam PF00994 Probable molybdopterin binding domain 182 319 1.0E-28 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 Gene3D G3DSA:2.170.190.11 52 143 1.5E-27 T 22-04-2016 TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 PANTHER PTHR10192:SF11 1 404 5.3E-189 T 22-04-2016 TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 SUPERFAMILY SSF63882 9 178 1.01E-52 T 22-04-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS08955 8898a6f268d01fff0617f37ea13f2204 406 Gene3D G3DSA:3.40.980.10 164 333 4.8E-68 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS13305 aa552be12b1d83c2597f76de142f2570 172 Pfam PF01202 Shikimate kinase 13 169 2.5E-53 T 22-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS13305 aa552be12b1d83c2597f76de142f2570 172 PANTHER PTHR21087 1 170 8.8E-68 T 22-04-2016 TOLA_RS13305 aa552be12b1d83c2597f76de142f2570 172 PRINTS PR01100 Shikimate kinase family signature 7 22 1.7E-28 T 22-04-2016 TOLA_RS13305 aa552be12b1d83c2597f76de142f2570 172 PRINTS PR01100 Shikimate kinase family signature 59 67 1.7E-28 T 22-04-2016 TOLA_RS13305 aa552be12b1d83c2597f76de142f2570 172 PRINTS PR01100 Shikimate kinase family signature 31 44 1.7E-28 T 22-04-2016 TOLA_RS13305 aa552be12b1d83c2597f76de142f2570 172 PRINTS PR01100 Shikimate kinase family signature 98 115 1.7E-28 T 22-04-2016 TOLA_RS13305 aa552be12b1d83c2597f76de142f2570 172 PRINTS PR01100 Shikimate kinase family signature 77 86 1.7E-28 T 22-04-2016 TOLA_RS13305 aa552be12b1d83c2597f76de142f2570 172 ProSitePatterns PS01128 Shikimate kinase signature. 60 85 - T 22-04-2016 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS13305 aa552be12b1d83c2597f76de142f2570 172 Hamap MF_00109 Shikimate kinase [aroK]. 4 171 28.857 T 22-04-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS13305 aa552be12b1d83c2597f76de142f2570 172 SUPERFAMILY SSF52540 4 170 4.54E-32 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13305 aa552be12b1d83c2597f76de142f2570 172 Gene3D G3DSA:3.40.50.300 2 170 3.2E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 Gene3D G3DSA:3.40.50.1370 145 318 2.3E-72 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 3.0E-45 T 22-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 332 80.78 T 22-04-2016 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 SUPERFAMILY SSF53671 4 332 1.83E-97 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 7.2E-25 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 7.2E-25 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 296 319 7.2E-25 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 7.2E-25 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 Gene3D G3DSA:3.40.50.1370 5 144 1.6E-53 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PANTHER PTHR11405 1 276 4.1E-190 T 22-04-2016 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PANTHER PTHR11405 295 332 4.1E-190 T 22-04-2016 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 329 3.4E-54 T 22-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 331 9.4E-131 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PANTHER PTHR11405:SF44 1 276 4.1E-190 T 22-04-2016 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PANTHER PTHR11405:SF44 295 332 4.1E-190 T 22-04-2016 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 2.6E-31 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 2.6E-31 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 2.6E-31 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 310 321 2.6E-31 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS12505 4ef0a9ed4722e1fc4e7751ebd464c3be 333 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 2.6E-31 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS11690 aa61d79473f22a4b3771f364bb3c7295 126 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 3.7E-53 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 TOLA_RS11690 aa61d79473f22a4b3771f364bb3c7295 126 Gene3D G3DSA:2.40.40.20 1 123 2.2E-54 T 22-04-2016 TOLA_RS11690 aa61d79473f22a4b3771f364bb3c7295 126 PANTHER PTHR21012 2 126 1.8E-65 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 TOLA_RS11690 aa61d79473f22a4b3771f364bb3c7295 126 SUPERFAMILY SSF50692 1 116 2.86E-48 T 22-04-2016 IPR009010 Aspartate decarboxylase-like domain TOLA_RS11690 aa61d79473f22a4b3771f364bb3c7295 126 PANTHER PTHR21012:SF0 2 126 1.8E-65 T 22-04-2016 TOLA_RS11690 aa61d79473f22a4b3771f364bb3c7295 126 PIRSF PIRSF006246 1 124 5.8E-53 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 TOLA_RS11690 aa61d79473f22a4b3771f364bb3c7295 126 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 70.913 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 TOLA_RS11690 aa61d79473f22a4b3771f364bb3c7295 126 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 123 4.0E-42 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 TOLA_RS11690 aa61d79473f22a4b3771f364bb3c7295 126 Pfam PF02261 Aspartate decarboxylase 1 114 3.0E-49 T 22-04-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 TOLA_RS06195 002b370c8d7d104e5eba25152f5cc43e 238 Gene3D G3DSA:3.40.190.10 108 199 1.0E-20 T 22-04-2016 TOLA_RS06195 002b370c8d7d104e5eba25152f5cc43e 238 PANTHER PTHR30632 4 237 1.9E-19 T 22-04-2016 TOLA_RS06195 002b370c8d7d104e5eba25152f5cc43e 238 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 30 234 8.1E-26 T 22-04-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 TOLA_RS06195 002b370c8d7d104e5eba25152f5cc43e 238 Pfam PF13531 Bacterial extracellular solute-binding protein 23 237 1.7E-23 T 22-04-2016 TOLA_RS06195 002b370c8d7d104e5eba25152f5cc43e 238 Gene3D G3DSA:3.40.190.10 200 234 1.1E-5 T 22-04-2016 TOLA_RS06195 002b370c8d7d104e5eba25152f5cc43e 238 Gene3D G3DSA:3.40.190.10 27 107 1.1E-5 T 22-04-2016 TOLA_RS06195 002b370c8d7d104e5eba25152f5cc43e 238 SUPERFAMILY SSF53850 19 237 2.82E-42 T 22-04-2016 TOLA_RS01645 efce6e8b3b596ccd12467dd212b0b623 215 Gene3D G3DSA:3.40.30.10 13 164 8.6E-59 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS01645 efce6e8b3b596ccd12467dd212b0b623 215 PANTHER PTHR10681 10 215 3.6E-73 T 22-04-2016 TOLA_RS01645 efce6e8b3b596ccd12467dd212b0b623 215 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 163 198 2.3E-11 T 22-04-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS01645 efce6e8b3b596ccd12467dd212b0b623 215 PIRSF PIRSF000239 6 214 1.3E-75 T 22-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 TOLA_RS01645 efce6e8b3b596ccd12467dd212b0b623 215 Hamap MF_00401 Peroxiredoxin. 11 215 42.4 T 22-04-2016 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS01645 efce6e8b3b596ccd12467dd212b0b623 215 SUPERFAMILY SSF52833 10 213 5.1E-69 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS01645 efce6e8b3b596ccd12467dd212b0b623 215 Gene3D G3DSA:3.30.1020.10 165 214 7.9E-20 T 22-04-2016 TOLA_RS01645 efce6e8b3b596ccd12467dd212b0b623 215 Pfam PF00578 AhpC/TSA family 14 142 1.8E-35 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS13205 996e7c0ee1bc403dee4d642be12b770a 236 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 62 77 - T 22-04-2016 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 TOLA_RS13205 996e7c0ee1bc403dee4d642be12b770a 236 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 2 235 52.117 T 22-04-2016 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 TOLA_RS13205 996e7c0ee1bc403dee4d642be12b770a 236 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 5 234 8.8E-118 T 22-04-2016 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 TOLA_RS13205 996e7c0ee1bc403dee4d642be12b770a 236 Gene3D G3DSA:3.40.50.1580 9 233 1.1E-83 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TOLA_RS13205 996e7c0ee1bc403dee4d642be12b770a 236 Pfam PF01048 Phosphorylase superfamily 17 223 5.1E-41 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TOLA_RS13205 996e7c0ee1bc403dee4d642be12b770a 236 PANTHER PTHR21234 3 234 1.7E-81 T 22-04-2016 IPR018017 Nucleoside phosphorylase TOLA_RS13205 996e7c0ee1bc403dee4d642be12b770a 236 SUPERFAMILY SSF53167 3 234 1.96E-94 T 22-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TOLA_RS13205 996e7c0ee1bc403dee4d642be12b770a 236 PANTHER PTHR21234:SF8 3 234 1.7E-81 T 22-04-2016 TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 SUPERFAMILY SSF82679 6 116 1.7E-40 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 Gene3D G3DSA:3.30.70.940 6 116 1.7E-44 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 Pfam PF02357 Transcription termination factor nusG 6 111 3.1E-26 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 PRINTS PR00338 Transcription termination factor NUSG signature 60 72 1.0E-20 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 PRINTS PR00338 Transcription termination factor NUSG signature 138 153 1.0E-20 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 PRINTS PR00338 Transcription termination factor NUSG signature 156 172 1.0E-20 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 ProSitePatterns PS01014 Transcription termination factor nusG signature. 163 172 - T 22-04-2016 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 Pfam PF00467 KOW motif 129 163 4.8E-7 T 22-04-2016 IPR005824 KOW TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 SMART SM00738 5 114 1.3E-50 T 22-04-2016 IPR006645 NusG, N-terminal GO:0006355 TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 Gene3D G3DSA:2.30.30.30 119 180 7.3E-30 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 PANTHER PTHR30265 1 180 5.8E-82 T 22-04-2016 TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 8 180 6.4E-70 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 5 180 25.717 T 22-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 SUPERFAMILY SSF50104 124 180 1.35E-18 T 22-04-2016 IPR008991 Translation protein SH3-like domain TOLA_RS14275 960cdd42f2ef0de514a8f36ef2209b2c 180 SMART SM00739 126 153 1.3E-5 T 22-04-2016 IPR005824 KOW TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 Gene3D G3DSA:3.90.740.10 206 390 4.9E-56 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 2 929 21.49 T 22-04-2016 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 Gene3D G3DSA:1.10.730.10 643 789 1.8E-45 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 Gene3D G3DSA:3.40.50.620 407 638 7.5E-137 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 Gene3D G3DSA:3.40.50.620 13 200 7.5E-137 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 844 2.7E-298 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 SUPERFAMILY SSF47323 653 929 4.3E-80 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 237 260 8.1E-34 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 562 571 8.1E-34 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 527 540 8.1E-34 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 402 417 8.1E-34 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 8.1E-34 T 22-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 PANTHER PTHR11946 285 911 0.0 T 22-04-2016 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 PANTHER PTHR11946 6 258 0.0 T 22-04-2016 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 SUPERFAMILY SSF50677 204 404 6.28E-56 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 642 8.8E-230 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 PANTHER PTHR11946:SF11 285 911 0.0 T 22-04-2016 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 PANTHER PTHR11946:SF11 6 258 0.0 T 22-04-2016 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 SUPERFAMILY SSF52374 3 202 1.26E-135 T 22-04-2016 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 SUPERFAMILY SSF52374 404 648 1.26E-135 T 22-04-2016 TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 Pfam PF06827 Zinc finger found in FPG and IleRS 900 926 4.3E-6 T 22-04-2016 IPR010663 Zinc finger, FPG/IleRS-type TOLA_RS15150 bacf0517b17341281d5c7c662e4b2345 938 Pfam PF08264 Anticodon-binding domain of tRNA 686 842 1.7E-29 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 TOLA_RS16395 a12bed583dfb3535af9589dae64f9fe0 218 PANTHER PTHR34183:SF1 83 212 1.6E-59 T 22-04-2016 TOLA_RS16395 a12bed583dfb3535af9589dae64f9fe0 218 SUPERFAMILY SSF50685 114 206 1.15E-12 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain TOLA_RS16395 a12bed583dfb3535af9589dae64f9fe0 218 Pfam PF03330 Lytic transglycolase 113 203 1.0E-22 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain TOLA_RS16395 a12bed583dfb3535af9589dae64f9fe0 218 PANTHER PTHR34183 83 212 1.6E-59 T 22-04-2016 TOLA_RS16395 a12bed583dfb3535af9589dae64f9fe0 218 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 116 215 8.3E-42 T 22-04-2016 IPR012997 Rare lipoprotein A TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 1 309 1.3E-96 T 22-04-2016 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 121 8.5E-12 T 22-04-2016 TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 214 328 2.7E-33 T 22-04-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 Gene3D G3DSA:3.30.565.10 2 209 5.6E-74 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 SUPERFAMILY SSF55874 1 203 2.23E-53 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 SUPERFAMILY SSF118116 411 592 1.06E-20 T 22-04-2016 TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 22-04-2016 IPR014762 DNA mismatch repair, conserved site TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 SMART SM00853 414 555 0.0046 T 22-04-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 Gene3D G3DSA:3.30.230.10 217 328 4.1E-34 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 PANTHER PTHR10073 3 329 3.0E-144 T 22-04-2016 TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 SMART SM01340 212 329 6.7E-47 T 22-04-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 591 23.897 T 22-04-2016 IPR020667 DNA mismatch repair protein, MutL GO:0006298 TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 Pfam PF08676 MutL C terminal dimerisation domain 415 528 2.3E-16 T 22-04-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 TOLA_RS12135 00efd9e8d5117652f7f9770b4147d4fa 594 SUPERFAMILY SSF54211 191 329 2.84E-34 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 Pfam PF02780 Transketolase, C-terminal domain 547 659 4.8E-18 T 22-04-2016 IPR033248 Transketolase, C-terminal domain TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 TIGRFAM TIGR00232 tktlase_bact: transketolase 10 666 0.0 T 22-04-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 Pfam PF02779 Transketolase, pyrimidine binding domain 359 529 9.5E-47 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 PANTHER PTHR11624:SF1 345 669 0.0 T 22-04-2016 TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 PANTHER PTHR11624:SF1 4 312 0.0 T 22-04-2016 TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 SUPERFAMILY SSF52922 537 668 9.29E-43 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 SUPERFAMILY SSF52518 8 325 7.5E-120 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 ProSitePatterns PS00802 Transketolase signature 2. 471 487 - T 22-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 SMART SM00861 359 529 2.8E-68 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 8 338 1.2E-165 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 Gene3D G3DSA:3.40.50.970 7 326 9.2E-130 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 ProSitePatterns PS00801 Transketolase signature 1. 16 36 - T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 PANTHER PTHR11624 345 669 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 PANTHER PTHR11624 4 312 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 SUPERFAMILY SSF52518 338 530 5.56E-69 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 Gene3D G3DSA:3.40.50.920 542 668 4.9E-51 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS16185 9857ffeb585ad9725b0126cdf14b0388 669 Gene3D G3DSA:3.40.50.970 332 537 2.5E-81 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS00195 d0ce68b1992189dead54be721c8a75cb 369 Pfam PF08402 TOBE domain 281 353 9.3E-11 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 TOLA_RS00195 d0ce68b1992189dead54be721c8a75cb 369 PANTHER PTHR24220 5 257 1.3E-176 T 22-04-2016 TOLA_RS00195 d0ce68b1992189dead54be721c8a75cb 369 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS00195 d0ce68b1992189dead54be721c8a75cb 369 Pfam PF00005 ABC transporter 20 161 1.4E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS00195 d0ce68b1992189dead54be721c8a75cb 369 SUPERFAMILY SSF50331 236 362 2.16E-32 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS00195 d0ce68b1992189dead54be721c8a75cb 369 Gene3D G3DSA:2.40.50.100 239 294 2.3E-19 T 22-04-2016 TOLA_RS00195 d0ce68b1992189dead54be721c8a75cb 369 Gene3D G3DSA:2.40.50.140 295 345 2.0E-16 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS00195 d0ce68b1992189dead54be721c8a75cb 369 PANTHER PTHR24220:SF572 5 257 1.3E-176 T 22-04-2016 TOLA_RS00195 d0ce68b1992189dead54be721c8a75cb 369 SMART SM00382 28 210 4.6E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS00195 d0ce68b1992189dead54be721c8a75cb 369 SUPERFAMILY SSF52540 5 243 8.54E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00195 d0ce68b1992189dead54be721c8a75cb 369 Gene3D G3DSA:3.40.50.300 6 234 3.6E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01410 a5166e60920858e2d2d163dc0a8cc714 372 PANTHER PTHR30024 35 159 1.3E-16 T 22-04-2016 TOLA_RS01410 a5166e60920858e2d2d163dc0a8cc714 372 Gene3D G3DSA:3.40.190.10 118 258 7.1E-18 T 22-04-2016 TOLA_RS01410 a5166e60920858e2d2d163dc0a8cc714 372 Gene3D G3DSA:3.40.190.10 30 102 8.2E-8 T 22-04-2016 TOLA_RS01410 a5166e60920858e2d2d163dc0a8cc714 372 Gene3D G3DSA:3.40.190.10 263 313 8.2E-8 T 22-04-2016 TOLA_RS01410 a5166e60920858e2d2d163dc0a8cc714 372 PANTHER PTHR30024:SF5 35 159 1.3E-16 T 22-04-2016 TOLA_RS01410 a5166e60920858e2d2d163dc0a8cc714 372 SUPERFAMILY SSF53850 30 315 9.06E-22 T 22-04-2016 TOLA_RS01410 a5166e60920858e2d2d163dc0a8cc714 372 Pfam PF16868 NMT1-like family 30 161 1.6E-16 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 SUPERFAMILY SSF48179 204 381 1.29E-45 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 149 372 8.2E-59 T 22-04-2016 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 150 162 - T 22-04-2016 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 Gene3D G3DSA:1.10.1040.10 203 381 2.5E-48 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 PANTHER PTHR30524 1 381 4.8E-185 T 22-04-2016 TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 PANTHER PTHR30524:SF0 1 381 4.8E-185 T 22-04-2016 TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 1 123 3.8E-22 T 22-04-2016 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 Gene3D G3DSA:3.40.50.720 2 201 4.2E-32 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 SUPERFAMILY SSF51735 1 202 2.6E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 378 40.928 T 22-04-2016 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 PRINTS PR00084 Mannitol dehydrogenase signature 150 163 2.7E-17 T 22-04-2016 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 PRINTS PR00084 Mannitol dehydrogenase signature 114 127 2.7E-17 T 22-04-2016 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 2.7E-17 T 22-04-2016 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS01495 762bdc910600c84bcd5e9c429df67744 382 PRINTS PR00084 Mannitol dehydrogenase signature 170 185 2.7E-17 T 22-04-2016 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS14480 0a4e8815cb075da72caea7c2e8a6e5f2 345 Gene3D G3DSA:3.40.50.300 1 138 4.7E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14480 0a4e8815cb075da72caea7c2e8a6e5f2 345 Pfam PF06144 DNA polymerase III, delta subunit 20 189 7.5E-31 T 22-04-2016 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 TOLA_RS14480 0a4e8815cb075da72caea7c2e8a6e5f2 345 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 213 330 7.0E-21 T 22-04-2016 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS14480 0a4e8815cb075da72caea7c2e8a6e5f2 345 SUPERFAMILY SSF48019 211 330 1.7E-24 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 TOLA_RS14480 0a4e8815cb075da72caea7c2e8a6e5f2 345 Gene3D G3DSA:1.20.272.20 222 335 4.5E-36 T 22-04-2016 TOLA_RS14480 0a4e8815cb075da72caea7c2e8a6e5f2 345 Gene3D G3DSA:1.10.8.60 145 221 1.3E-25 T 22-04-2016 TOLA_RS14480 0a4e8815cb075da72caea7c2e8a6e5f2 345 SUPERFAMILY SSF52540 1 207 5.18E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14480 0a4e8815cb075da72caea7c2e8a6e5f2 345 PANTHER PTHR34388 1 342 1.2E-69 T 22-04-2016 TOLA_RS14480 0a4e8815cb075da72caea7c2e8a6e5f2 345 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 17 331 5.6E-80 T 22-04-2016 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 311 514 1.5E-17 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 Gene3D G3DSA:1.20.58.370 15 105 1.8E-33 T 22-04-2016 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 SUPERFAMILY SSF160964 27 273 4.32E-79 T 22-04-2016 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 Gene3D G3DSA:2.40.430.10 129 206 4.6E-29 T 22-04-2016 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 Gene3D G3DSA:3.10.650.10 207 282 1.7E-34 T 22-04-2016 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 Pfam PF14785 Maltose transport system permease protein MalF P2 domain 110 273 5.7E-60 T 22-04-2016 IPR029345 Maltose transport system permease protein MalF, P2 domain TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 PANTHER PTHR30193 68 115 1.8E-137 T 22-04-2016 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 PANTHER PTHR30193 272 528 1.8E-137 T 22-04-2016 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 PANTHER PTHR30193 30 50 1.8E-137 T 22-04-2016 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 SUPERFAMILY SSF161098 274 516 2.62E-59 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 Gene3D G3DSA:1.10.3720.10 287 522 2.5E-61 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 PANTHER PTHR30193:SF22 68 115 1.8E-137 T 22-04-2016 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 PANTHER PTHR30193:SF22 272 528 1.8E-137 T 22-04-2016 TOLA_RS00220 6cce9da8dd10753e8a1c76e5b3d016c9 528 PANTHER PTHR30193:SF22 30 50 1.8E-137 T 22-04-2016 TOLA_RS06015 c2156e240c70797258ebf0fe071492f7 268 PANTHER PTHR30502 1 262 2.1E-188 T 22-04-2016 TOLA_RS06015 c2156e240c70797258ebf0fe071492f7 268 Gene3D G3DSA:3.20.20.60 5 252 6.4E-77 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS06015 c2156e240c70797258ebf0fe071492f7 268 SUPERFAMILY SSF51621 5 255 1.85E-78 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS06015 c2156e240c70797258ebf0fe071492f7 268 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 19 244 1.6E-62 T 22-04-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 TOLA_RS06015 c2156e240c70797258ebf0fe071492f7 268 PANTHER PTHR30502:SF5 1 262 2.1E-188 T 22-04-2016 TOLA_RS09545 fffeffdbc8de1ff85606b3c170c36773 90 PANTHER PTHR11751 1 86 1.2E-21 T 22-04-2016 TOLA_RS09545 fffeffdbc8de1ff85606b3c170c36773 90 PANTHER PTHR11751:SF314 1 86 1.2E-21 T 22-04-2016 TOLA_RS09545 fffeffdbc8de1ff85606b3c170c36773 90 SUPERFAMILY SSF53383 2 87 4.96E-17 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS09545 fffeffdbc8de1ff85606b3c170c36773 90 Gene3D G3DSA:3.90.1150.10 2 86 1.9E-16 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS05585 cdb67ed0783c0b847214e7bc50dd6556 159 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 77 155 1.4E-32 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 TOLA_RS05585 cdb67ed0783c0b847214e7bc50dd6556 159 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 75 154 2.3E-35 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 TOLA_RS05585 cdb67ed0783c0b847214e7bc50dd6556 159 PANTHER PTHR10815:SF5 7 154 6.9E-57 T 22-04-2016 TOLA_RS05585 cdb67ed0783c0b847214e7bc50dd6556 159 Gene3D G3DSA:1.10.10.10 74 155 1.3E-34 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05585 cdb67ed0783c0b847214e7bc50dd6556 159 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 3 157 35.285 T 22-04-2016 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 TOLA_RS05585 cdb67ed0783c0b847214e7bc50dd6556 159 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 8 71 1.1E-4 T 22-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 TOLA_RS05585 cdb67ed0783c0b847214e7bc50dd6556 159 SUPERFAMILY SSF46767 74 155 6.67E-32 T 22-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 TOLA_RS05585 cdb67ed0783c0b847214e7bc50dd6556 159 SUPERFAMILY SSF53155 4 78 1.04E-15 T 22-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 TOLA_RS05585 cdb67ed0783c0b847214e7bc50dd6556 159 PANTHER PTHR10815 7 154 6.9E-57 T 22-04-2016 TOLA_RS05585 cdb67ed0783c0b847214e7bc50dd6556 159 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 125 131 - T 22-04-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 TOLA_RS15300 300ac1083d0769780f58e30ba6762516 292 PANTHER PTHR22911 6 292 3.1E-132 T 22-04-2016 TOLA_RS15300 300ac1083d0769780f58e30ba6762516 292 SUPERFAMILY SSF103481 182 284 1.02E-7 T 22-04-2016 TOLA_RS15300 300ac1083d0769780f58e30ba6762516 292 TIGRFAM TIGR00688 rarD: protein RarD 6 259 3.2E-83 T 22-04-2016 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 TOLA_RS15300 300ac1083d0769780f58e30ba6762516 292 PANTHER PTHR22911:SF41 6 292 3.1E-132 T 22-04-2016 TOLA_RS15300 300ac1083d0769780f58e30ba6762516 292 SUPERFAMILY SSF103481 40 141 9.81E-14 T 22-04-2016 TOLA_RS15300 300ac1083d0769780f58e30ba6762516 292 Pfam PF00892 EamA-like transporter family 6 140 2.0E-16 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS12155 07fefbbb3437af49fd6bb4fa4ece92f7 375 PANTHER PTHR30002:SF4 2 367 7.4E-182 T 22-04-2016 TOLA_RS12155 07fefbbb3437af49fd6bb4fa4ece92f7 375 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 7 315 50.295 T 22-04-2016 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS12155 07fefbbb3437af49fd6bb4fa4ece92f7 375 Pfam PF13484 4Fe-4S double cluster binding domain 193 256 9.1E-20 T 22-04-2016 TOLA_RS12155 07fefbbb3437af49fd6bb4fa4ece92f7 375 SUPERFAMILY SSF54862 171 286 7.53E-18 T 22-04-2016 TOLA_RS12155 07fefbbb3437af49fd6bb4fa4ece92f7 375 Gene3D G3DSA:3.30.70.20 192 262 1.9E-6 T 22-04-2016 TOLA_RS12155 07fefbbb3437af49fd6bb4fa4ece92f7 375 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 193 204 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS12155 07fefbbb3437af49fd6bb4fa4ece92f7 375 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 14 348 1.2E-155 T 22-04-2016 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS12155 07fefbbb3437af49fd6bb4fa4ece92f7 375 Pfam PF08331 Domain of unknown function (DUF1730) 62 140 2.3E-25 T 22-04-2016 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS12155 07fefbbb3437af49fd6bb4fa4ece92f7 375 PANTHER PTHR30002 2 367 7.4E-182 T 22-04-2016 TOLA_RS11505 0f2b5059b4d2fc5043b1375bbd45d3c9 415 Gene3D G3DSA:1.10.443.10 216 383 3.2E-22 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS11505 0f2b5059b4d2fc5043b1375bbd45d3c9 415 Pfam PF00589 Phage integrase family 215 378 2.2E-20 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS11505 0f2b5059b4d2fc5043b1375bbd45d3c9 415 PANTHER PTHR30629 1 400 7.3E-154 T 22-04-2016 TOLA_RS11505 0f2b5059b4d2fc5043b1375bbd45d3c9 415 Pfam PF13356 Domain of unknown function (DUF4102) 6 92 9.9E-19 T 22-04-2016 IPR025166 Domain of unknown function DUF4102 TOLA_RS11505 0f2b5059b4d2fc5043b1375bbd45d3c9 415 Gene3D G3DSA:1.10.150.130 106 207 4.4E-15 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal TOLA_RS11505 0f2b5059b4d2fc5043b1375bbd45d3c9 415 SUPERFAMILY SSF56349 106 388 4.41E-58 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TOLA_RS11505 0f2b5059b4d2fc5043b1375bbd45d3c9 415 PANTHER PTHR30629:SF2 1 400 7.3E-154 T 22-04-2016 TOLA_RS08675 0b1228292fdcba0d1bc8c02cedb899eb 286 PIRSF PIRSF033887 1 278 8.8E-71 T 22-04-2016 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00040+2.7.1.17|KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443|UniPathway: UPA00148 TOLA_RS08675 0b1228292fdcba0d1bc8c02cedb899eb 286 SUPERFAMILY SSF54211 3 140 3.42E-21 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS08675 0b1228292fdcba0d1bc8c02cedb899eb 286 PANTHER PTHR20861:SF5 28 286 3.0E-77 T 22-04-2016 TOLA_RS08675 0b1228292fdcba0d1bc8c02cedb899eb 286 Gene3D G3DSA:3.30.230.10 36 120 2.9E-11 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS08675 0b1228292fdcba0d1bc8c02cedb899eb 286 PANTHER PTHR20861 28 286 3.0E-77 T 22-04-2016 TOLA_RS08675 0b1228292fdcba0d1bc8c02cedb899eb 286 Pfam PF00288 GHMP kinases N terminal domain 72 120 1.6E-8 T 22-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 TOLA_RS02755 957ad905bf24c065b786bee231981592 132 PANTHER PTHR22769 1 126 1.8E-34 T 22-04-2016 TOLA_RS02755 957ad905bf24c065b786bee231981592 132 Gene3D G3DSA:3.90.79.10 5 128 8.0E-32 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS02755 957ad905bf24c065b786bee231981592 132 Pfam PF00293 NUDIX domain 8 124 9.9E-18 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TOLA_RS02755 957ad905bf24c065b786bee231981592 132 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TOLA_RS02755 957ad905bf24c065b786bee231981592 132 PRINTS PR00502 NUDIX hydrolase family signature 47 62 2.6E-9 T 22-04-2016 IPR020476 NUDIX hydrolase TOLA_RS02755 957ad905bf24c065b786bee231981592 132 PRINTS PR00502 NUDIX hydrolase family signature 33 47 2.6E-9 T 22-04-2016 IPR020476 NUDIX hydrolase TOLA_RS02755 957ad905bf24c065b786bee231981592 132 TIGRFAM TIGR00586 mutt: mutator mutT protein 1 127 1.1E-37 T 22-04-2016 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 TOLA_RS02755 957ad905bf24c065b786bee231981592 132 SUPERFAMILY SSF55811 1 127 7.99E-36 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS02755 957ad905bf24c065b786bee231981592 132 PANTHER PTHR22769:SF36 1 126 1.8E-34 T 22-04-2016 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 TOLA_RS06285 7a7a07d53f581251601ffe2af3f21f8c 365 Gene3D G3DSA:1.10.3720.10 155 358 3.5E-39 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06285 7a7a07d53f581251601ffe2af3f21f8c 365 SUPERFAMILY SSF161098 155 345 2.49E-37 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06285 7a7a07d53f581251601ffe2af3f21f8c 365 PANTHER PTHR30085 63 365 1.1E-152 T 22-04-2016 TOLA_RS06285 7a7a07d53f581251601ffe2af3f21f8c 365 PANTHER PTHR30085:SF3 63 365 1.1E-152 T 22-04-2016 TOLA_RS06285 7a7a07d53f581251601ffe2af3f21f8c 365 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 173 350 2.5E-21 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06285 7a7a07d53f581251601ffe2af3f21f8c 365 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 155 251 6.1E-20 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.7E-20 T 22-04-2016 TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.7E-18 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.7E-18 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.7E-18 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 Gene3D G3DSA:3.30.70.920 54 150 2.0E-25 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 Pfam PF01037 Lrp/AsnC ligand binding domain 67 140 4.4E-18 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 PANTHER PTHR30154 1 150 8.6E-60 T 22-04-2016 TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 SUPERFAMILY SSF54909 61 150 1.61E-17 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 22-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 Gene3D G3DSA:1.10.10.10 2 52 1.5E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 PANTHER PTHR30154:SF28 1 150 8.6E-60 T 22-04-2016 TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 SUPERFAMILY SSF46785 1 61 1.07E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08415 879c6d59dfe19d37a2b0e58213a947af 150 SMART SM00344 1 110 7.5E-46 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TOLA_RS01940 06082e6d05bf73c09438b505bc332ca1 322 SUPERFAMILY SSF46689 272 321 2.64E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS01940 06082e6d05bf73c09438b505bc332ca1 322 SMART SM00342 237 319 1.7E-19 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS01940 06082e6d05bf73c09438b505bc332ca1 322 Gene3D G3DSA:1.10.10.60 274 322 2.7E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS01940 06082e6d05bf73c09438b505bc332ca1 322 Pfam PF12833 Helix-turn-helix domain 244 320 1.0E-18 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS01940 06082e6d05bf73c09438b505bc332ca1 322 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 288 303 2.9E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS01940 06082e6d05bf73c09438b505bc332ca1 322 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 303 319 2.9E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS01940 06082e6d05bf73c09438b505bc332ca1 322 PANTHER PTHR11019 239 320 1.4E-19 T 22-04-2016 TOLA_RS07640 89b2d8fe0081ab608710d10cf4e20188 547 SUPERFAMILY SSF53474 45 545 7.23E-116 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS07640 89b2d8fe0081ab608710d10cf4e20188 547 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 118 128 - T 22-04-2016 IPR019819 Carboxylesterase type B, conserved site TOLA_RS07640 89b2d8fe0081ab608710d10cf4e20188 547 Pfam PF00135 Carboxylesterase family 45 542 3.9E-116 T 22-04-2016 IPR002018 Carboxylesterase, type B TOLA_RS07640 89b2d8fe0081ab608710d10cf4e20188 547 Gene3D G3DSA:3.40.50.1820 41 545 6.7E-144 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS07640 89b2d8fe0081ab608710d10cf4e20188 547 PANTHER PTHR11559 42 508 4.5E-152 T 22-04-2016 TOLA_RS07640 89b2d8fe0081ab608710d10cf4e20188 547 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 216 231 - T 22-04-2016 IPR019826 Carboxylesterase type B, active site TOLA_RS01590 19d426c007f9d72f618d2d426b4ad1b7 611 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 611 1.1E-261 T 22-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 TOLA_RS01590 19d426c007f9d72f618d2d426b4ad1b7 611 Pfam PF13522 Glutamine amidotransferase domain 65 183 5.4E-23 T 22-04-2016 TOLA_RS01590 19d426c007f9d72f618d2d426b4ad1b7 611 Pfam PF01380 SIS domain 291 419 6.4E-33 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 TOLA_RS01590 19d426c007f9d72f618d2d426b4ad1b7 611 Pfam PF01380 SIS domain 464 593 1.2E-24 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 TOLA_RS01590 19d426c007f9d72f618d2d426b4ad1b7 611 Gene3D G3DSA:3.40.50.10490 246 447 1.6E-66 T 22-04-2016 TOLA_RS01590 19d426c007f9d72f618d2d426b4ad1b7 611 PANTHER PTHR10937:SF0 1 611 0.0 T 22-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 TOLA_RS01590 19d426c007f9d72f618d2d426b4ad1b7 611 SUPERFAMILY SSF56235 2 234 8.15E-76 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS01590 19d426c007f9d72f618d2d426b4ad1b7 611 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 611 41.04 T 22-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 TOLA_RS01590 19d426c007f9d72f618d2d426b4ad1b7 611 Gene3D G3DSA:3.60.20.10 2 238 1.3E-80 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS01590 19d426c007f9d72f618d2d426b4ad1b7 611 Gene3D G3DSA:3.40.50.10490 448 611 2.2E-66 T 22-04-2016 TOLA_RS01590 19d426c007f9d72f618d2d426b4ad1b7 611 SUPERFAMILY SSF53697 246 611 7.75E-111 T 22-04-2016 TOLA_RS01590 19d426c007f9d72f618d2d426b4ad1b7 611 PANTHER PTHR10937 1 611 0.0 T 22-04-2016 TOLA_RS00660 17c668a2920fb7f8268d0643d0291034 106 SUPERFAMILY SSF47598 4 105 1.93E-54 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 TOLA_RS00660 17c668a2920fb7f8268d0643d0291034 106 Gene3D G3DSA:1.10.140.10 4 105 2.4E-59 T 22-04-2016 IPR023453 Methionine repressor MetJ domain TOLA_RS00660 17c668a2920fb7f8268d0643d0291034 106 Pfam PF01340 Met Apo-repressor, MetJ 5 98 2.0E-56 T 22-04-2016 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 TOLA_RS00660 17c668a2920fb7f8268d0643d0291034 106 ProDom PD020365 REPRESSOR MET BIOSYNTHESIS TRANSCRIPTION METJ METHIONINE REGULON DNA-BINDING REGULATORY AMINO-ACID 11 102 5.0E-41 T 22-04-2016 IPR002084 Methionine repressor MetJ GO:0003700|GO:0006355|GO:0006555 TOLA_RS10570 8c68f233acf29bd1cf1dea058da58b4d 272 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 26 93 1.0E-15 T 22-04-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS10570 8c68f233acf29bd1cf1dea058da58b4d 272 PANTHER PTHR21089:SF9 1 271 1.8E-178 T 22-04-2016 TOLA_RS10570 8c68f233acf29bd1cf1dea058da58b4d 272 Gene3D G3DSA:3.40.50.720 111 267 2.0E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10570 8c68f233acf29bd1cf1dea058da58b4d 272 SUPERFAMILY SSF51735 106 266 3.54E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10570 8c68f233acf29bd1cf1dea058da58b4d 272 Gene3D G3DSA:3.40.192.10 25 110 1.3E-27 T 22-04-2016 TOLA_RS10570 8c68f233acf29bd1cf1dea058da58b4d 272 PANTHER PTHR21089 1 271 1.8E-178 T 22-04-2016 TOLA_RS10570 8c68f233acf29bd1cf1dea058da58b4d 272 SUPERFAMILY SSF53223 7 105 2.94E-26 T 22-04-2016 TOLA_RS03615 bda37517950578e0dc876a1dc2f1060b 198 Gene3D G3DSA:3.30.420.10 34 191 9.5E-36 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS03615 bda37517950578e0dc876a1dc2f1060b 198 PANTHER PTHR32552 1 198 8.3E-38 T 22-04-2016 TOLA_RS03615 bda37517950578e0dc876a1dc2f1060b 198 Pfam PF00665 Integrase core domain 38 152 1.6E-30 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 TOLA_RS03615 bda37517950578e0dc876a1dc2f1060b 198 SUPERFAMILY SSF53098 34 195 5.69E-40 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 PANTHER PTHR30376 3 283 8.2E-122 T 22-04-2016 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 SUPERFAMILY SSF88946 13 123 5.23E-40 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 Pfam PF04545 Sigma-70, region 4 228 279 3.2E-17 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 PIRSF PIRSF000770 7 284 5.0E-34 T 22-04-2016 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 Pfam PF00140 Sigma-70 factor, region 1.2 20 44 9.1E-5 T 22-04-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 Gene3D G3DSA:1.10.601.10 17 123 2.8E-35 T 22-04-2016 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 Pfam PF04542 Sigma-70 region 2 54 123 1.4E-17 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 252 278 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 15 283 5.7E-128 T 22-04-2016 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 Gene3D G3DSA:1.10.10.10 224 282 2.3E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15455 c08c61d74a6956248a184de176233084 284 SUPERFAMILY SSF88659 199 283 3.55E-18 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 3 284 52.529 T 22-04-2016 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 281 4.0E-34 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 PRINTS PR00046 Major sigma-70 factor signature 232 244 3.63E-19 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 PRINTS PR00046 Major sigma-70 factor signature 252 267 3.63E-19 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 PRINTS PR00046 Major sigma-70 factor signature 78 91 3.63E-19 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15455 c08c61d74a6956248a184de176233084 284 PRINTS PR00046 Major sigma-70 factor signature 267 278 3.63E-19 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS04720 544672c0c56902b5cdde7c4f0c43d79a 468 PANTHER PTHR22726:SF10 6 333 6.8E-99 T 22-04-2016 TOLA_RS04720 544672c0c56902b5cdde7c4f0c43d79a 468 PANTHER PTHR22726 6 333 6.8E-99 T 22-04-2016 TOLA_RS04720 544672c0c56902b5cdde7c4f0c43d79a 468 SUPERFAMILY SSF48452 288 437 1.36E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS04720 544672c0c56902b5cdde7c4f0c43d79a 468 Pfam PF01435 Peptidase family M48 52 238 5.0E-28 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TOLA_RS04720 544672c0c56902b5cdde7c4f0c43d79a 468 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 1 464 29.744 T 22-04-2016 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 TOLA_RS04720 544672c0c56902b5cdde7c4f0c43d79a 468 Gene3D G3DSA:3.30.2010.10 48 127 1.4E-15 T 22-04-2016 TOLA_RS04720 544672c0c56902b5cdde7c4f0c43d79a 468 Gene3D G3DSA:1.25.40.10 288 436 4.4E-10 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS04720 544672c0c56902b5cdde7c4f0c43d79a 468 Pfam PF14559 Tetratricopeptide repeat 336 400 1.0E-8 T 22-04-2016 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 PANTHER PTHR30386 172 461 6.3E-152 T 22-04-2016 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 PANTHER PTHR30386 1 122 6.3E-152 T 22-04-2016 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 PANTHER PTHR30386:SF4 172 461 6.3E-152 T 22-04-2016 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 PANTHER PTHR30386:SF4 1 122 6.3E-152 T 22-04-2016 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 29 461 1.4E-129 T 22-04-2016 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 Pfam PF13437 HlyD family secretion protein 313 413 9.8E-18 T 22-04-2016 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 Gene3D G3DSA:1.20.1600.10 165 256 2.9E-5 T 22-04-2016 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 Gene3D G3DSA:2.40.50.100 310 345 2.4E-16 T 22-04-2016 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 Gene3D G3DSA:2.40.50.100 71 101 2.4E-16 T 22-04-2016 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 SUPERFAMILY SSF111369 60 132 2.75E-6 T 22-04-2016 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 440 460 6.2E-47 T 22-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 382 405 6.2E-47 T 22-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 425 440 6.2E-47 T 22-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 37 60 6.2E-47 T 22-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 325 346 6.2E-47 T 22-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 358 382 6.2E-47 T 22-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 79 99 6.2E-47 T 22-04-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 TOLA_RS06440 ff06fd0d571f1888b574d96ecfab5b09 461 ProSitePatterns PS00543 HlyD family secretion proteins signature. 425 447 - T 22-04-2016 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 TOLA_RS14975 df0a17523be9be4376862a2124a556f4 193 Gene3D G3DSA:1.10.530.10 50 160 1.9E-8 T 22-04-2016 TOLA_RS14975 df0a17523be9be4376862a2124a556f4 193 SUPERFAMILY SSF53955 12 162 2.28E-22 T 22-04-2016 IPR023346 Lysozyme-like domain TOLA_RS14445 da634cb082d73d5d5a1b3add8d084aaa 98 PANTHER PTHR34477:SF1 4 90 3.9E-31 T 22-04-2016 TOLA_RS14445 da634cb082d73d5d5a1b3add8d084aaa 98 PANTHER PTHR34477 4 90 3.9E-31 T 22-04-2016 TOLA_RS14445 da634cb082d73d5d5a1b3add8d084aaa 98 Pfam PF01541 GIY-YIG catalytic domain 11 81 3.7E-15 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily TOLA_RS14445 da634cb082d73d5d5a1b3add8d084aaa 98 SUPERFAMILY SSF82771 11 81 8.63E-14 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 PANTHER PTHR24423:SF375 59 160 3.5E-147 T 22-04-2016 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 Pfam PF17203 Single cache domain 3 40 170 7.8E-22 T 22-04-2016 IPR033463 Single cache domain 3 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 SMART SM00387 423 531 3.2E-22 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 PANTHER PTHR24423:SF375 193 533 3.5E-147 T 22-04-2016 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 Pfam PF00989 PAS fold 216 316 1.4E-7 T 22-04-2016 IPR013767 PAS fold GO:0006355 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 SUPERFAMILY SSF55785 219 316 5.82E-6 T 22-04-2016 IPR000014 PAS domain TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 Gene3D G3DSA:3.30.450.20 35 171 3.8E-44 T 22-04-2016 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 326 377 2.2E-11 T 22-04-2016 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 515 528 5.9E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 490 5.9E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 476 5.9E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 509 5.9E-13 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 SUPERFAMILY SSF55874 425 529 1.18E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 427 529 1.5E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 SUPERFAMILY SSF103190 42 170 1.29E-37 T 22-04-2016 IPR029151 Periplasmic sensor domain-like TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 PANTHER PTHR24423 59 160 3.5E-147 T 22-04-2016 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 Gene3D G3DSA:3.30.450.20 215 320 1.6E-10 T 22-04-2016 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 Gene3D G3DSA:3.30.565.10 425 529 8.6E-30 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 SUPERFAMILY SSF55890 329 465 3.01E-15 T 22-04-2016 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 PANTHER PTHR24423 193 533 3.5E-147 T 22-04-2016 TOLA_RS01145 18bdf978b561764b664828cedcb5729c 536 Gene3D G3DSA:1.10.287.130 321 379 6.3E-22 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 SUPERFAMILY SSF46785 5 65 3.33E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 SMART SM00420 6 58 4.5E-18 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 PANTHER PTHR30363 1 251 5.0E-91 T 22-04-2016 TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 22-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.4E-5 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.4E-5 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 SUPERFAMILY SSF100950 76 234 1.67E-23 T 22-04-2016 TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 7.1E-18 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 Gene3D G3DSA:1.10.10.10 1 55 1.9E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 PANTHER PTHR30363:SF4 1 251 5.0E-91 T 22-04-2016 TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 Pfam PF00455 DeoR C terminal sensor domain 76 230 3.8E-37 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 SMART SM01134 74 232 1.4E-39 T 22-04-2016 TOLA_RS15720 27439cac8652ad13a3cab075801b7ffb 251 Gene3D G3DSA:3.40.50.1360 77 214 2.5E-5 T 22-04-2016 TOLA_RS03170 7cbaf86afecdb75b624a0cc1eef84bce 212 PANTHER PTHR30506 4 206 1.0E-75 T 22-04-2016 TOLA_RS03170 7cbaf86afecdb75b624a0cc1eef84bce 212 PANTHER PTHR30506:SF3 4 206 1.0E-75 T 22-04-2016 TOLA_RS03170 7cbaf86afecdb75b624a0cc1eef84bce 212 Pfam PF03458 UPF0126 domain 99 171 2.2E-21 T 22-04-2016 IPR005115 Uncharacterised domain UPF0126 TOLA_RS03170 7cbaf86afecdb75b624a0cc1eef84bce 212 Pfam PF03458 UPF0126 domain 12 83 2.0E-20 T 22-04-2016 IPR005115 Uncharacterised domain UPF0126 TOLA_RS07565 80f8a13d60f8b10cd5a0bc3fab66a543 442 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 22-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS07565 80f8a13d60f8b10cd5a0bc3fab66a543 442 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 419 2.8E-166 T 22-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS07565 80f8a13d60f8b10cd5a0bc3fab66a543 442 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 442 73.497 T 22-04-2016 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS07565 80f8a13d60f8b10cd5a0bc3fab66a543 442 Pfam PF00764 Arginosuccinate synthase 16 410 7.8E-57 T 22-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS07565 80f8a13d60f8b10cd5a0bc3fab66a543 442 Gene3D G3DSA:3.90.1260.10 175 373 6.2E-64 T 22-04-2016 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS07565 80f8a13d60f8b10cd5a0bc3fab66a543 442 SUPERFAMILY SSF52402 3 187 2.09E-34 T 22-04-2016 TOLA_RS07565 80f8a13d60f8b10cd5a0bc3fab66a543 442 PANTHER PTHR11587:SF2 1 425 1.8E-175 T 22-04-2016 TOLA_RS07565 80f8a13d60f8b10cd5a0bc3fab66a543 442 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 22-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS07565 80f8a13d60f8b10cd5a0bc3fab66a543 442 PANTHER PTHR11587 1 425 1.8E-175 T 22-04-2016 TOLA_RS07565 80f8a13d60f8b10cd5a0bc3fab66a543 442 Gene3D G3DSA:3.40.50.620 4 174 1.6E-44 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS07565 80f8a13d60f8b10cd5a0bc3fab66a543 442 Gene3D G3DSA:1.10.287.400 377 440 3.2E-34 T 22-04-2016 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS07565 80f8a13d60f8b10cd5a0bc3fab66a543 442 SUPERFAMILY SSF69864 190 441 4.71E-79 T 22-04-2016 TOLA_RS09630 d3b2f14032b1765bdba8ceeeb0c7db0e 285 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 229 271 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TOLA_RS09630 d3b2f14032b1765bdba8ceeeb0c7db0e 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 275 2.8E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS09630 d3b2f14032b1765bdba8ceeeb0c7db0e 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 244 259 2.8E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS09630 d3b2f14032b1765bdba8ceeeb0c7db0e 285 SUPERFAMILY SSF46689 228 278 1.97E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09630 d3b2f14032b1765bdba8ceeeb0c7db0e 285 Pfam PF12833 Helix-turn-helix domain 199 276 5.5E-21 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS09630 d3b2f14032b1765bdba8ceeeb0c7db0e 285 PANTHER PTHR11019:SF11 42 283 1.4E-41 T 22-04-2016 TOLA_RS09630 d3b2f14032b1765bdba8ceeeb0c7db0e 285 Gene3D G3DSA:1.10.10.60 229 277 7.8E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09630 d3b2f14032b1765bdba8ceeeb0c7db0e 285 SMART SM00342 192 275 1.7E-30 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS09630 d3b2f14032b1765bdba8ceeeb0c7db0e 285 PANTHER PTHR11019 42 283 1.4E-41 T 22-04-2016 TOLA_RS09630 d3b2f14032b1765bdba8ceeeb0c7db0e 285 Gene3D G3DSA:1.10.10.60 171 228 8.7E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 PANTHER PTHR30349:SF11 62 100 4.3E-18 T 22-04-2016 TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 PANTHER PTHR30349:SF11 144 203 4.3E-18 T 22-04-2016 TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 PANTHER PTHR30349:SF11 220 349 4.3E-18 T 22-04-2016 TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 PANTHER PTHR30349:SF11 366 419 4.3E-18 T 22-04-2016 TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 Gene3D G3DSA:1.10.150.130 50 99 4.6E-9 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 Gene3D G3DSA:1.10.150.130 143 175 4.6E-9 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 PANTHER PTHR30349 62 100 4.3E-18 T 22-04-2016 TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 PANTHER PTHR30349 144 203 4.3E-18 T 22-04-2016 TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 PANTHER PTHR30349 220 349 4.3E-18 T 22-04-2016 TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 PANTHER PTHR30349 366 419 4.3E-18 T 22-04-2016 TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 Gene3D G3DSA:1.10.443.10 212 419 9.8E-25 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 SUPERFAMILY SSF56349 144 419 5.59E-28 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 SUPERFAMILY SSF56349 44 99 5.59E-28 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TOLA_RS07755 6fcad09ea5806f953c69c4d5967730cd 432 Pfam PF00589 Phage integrase family 209 413 3.4E-14 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS14945 1e20f9d103692953640facff8c42153f 247 Pfam PF00005 ABC transporter 18 159 7.6E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS14945 1e20f9d103692953640facff8c42153f 247 SUPERFAMILY SSF52540 2 233 2.07E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14945 1e20f9d103692953640facff8c42153f 247 PANTHER PTHR24220 3 225 6.6E-73 T 22-04-2016 TOLA_RS14945 1e20f9d103692953640facff8c42153f 247 SMART SM00382 26 207 3.1E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS14945 1e20f9d103692953640facff8c42153f 247 Gene3D G3DSA:3.40.50.300 1 226 4.3E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14945 1e20f9d103692953640facff8c42153f 247 PANTHER PTHR24220:SF581 3 225 6.6E-73 T 22-04-2016 TOLA_RS02020 fb57b5cfe762731ec2397738e496d9fa 424 SUPERFAMILY SSF52343 293 419 4.19E-25 T 22-04-2016 TOLA_RS02020 fb57b5cfe762731ec2397738e496d9fa 424 PANTHER PTHR11972:SF23 38 364 4.1E-52 T 22-04-2016 TOLA_RS02020 fb57b5cfe762731ec2397738e496d9fa 424 Pfam PF00175 Oxidoreductase NAD-binding domain 316 405 1.8E-8 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TOLA_RS02020 fb57b5cfe762731ec2397738e496d9fa 424 Pfam PF01794 Ferric reductase like transmembrane component 39 165 6.3E-15 T 22-04-2016 IPR013130 Ferric reductase transmembrane component-like domain TOLA_RS02020 fb57b5cfe762731ec2397738e496d9fa 424 Pfam PF08022 FAD-binding domain 216 302 1.7E-6 T 22-04-2016 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 TOLA_RS02020 fb57b5cfe762731ec2397738e496d9fa 424 PRINTS PR00409 Phthalate dioxygenase reductase family signature 292 306 1.2E-7 T 22-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 TOLA_RS02020 fb57b5cfe762731ec2397738e496d9fa 424 PRINTS PR00409 Phthalate dioxygenase reductase family signature 394 402 1.2E-7 T 22-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 TOLA_RS02020 fb57b5cfe762731ec2397738e496d9fa 424 PRINTS PR00409 Phthalate dioxygenase reductase family signature 314 333 1.2E-7 T 22-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 TOLA_RS02020 fb57b5cfe762731ec2397738e496d9fa 424 Gene3D G3DSA:2.40.30.10 211 297 1.0E-15 T 22-04-2016 TOLA_RS02020 fb57b5cfe762731ec2397738e496d9fa 424 SUPERFAMILY SSF63380 210 305 3.94E-18 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TOLA_RS02020 fb57b5cfe762731ec2397738e496d9fa 424 Gene3D G3DSA:3.40.50.80 298 411 9.9E-23 T 22-04-2016 TOLA_RS02020 fb57b5cfe762731ec2397738e496d9fa 424 PANTHER PTHR11972 38 364 4.1E-52 T 22-04-2016 TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 Gene3D G3DSA:1.20.59.10 1 83 9.9E-23 T 22-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 Gene3D G3DSA:3.40.50.720 84 246 2.1E-44 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 PANTHER PTHR21363:SF0 88 374 2.2E-66 T 22-04-2016 TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 Pfam PF02153 Prephenate dehydrogenase 138 345 9.8E-29 T 22-04-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 TIGRFAM TIGR01799 CM_T: chorismate mutase 5 87 9.8E-42 T 22-04-2016 IPR011277 Chorismate mutase, T-protein GO:0004106|GO:0005737|GO:0006571|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626|UniPathway: UPA00120|UniPathway: UPA00122 TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 SUPERFAMILY SSF48600 3 88 7.51E-23 T 22-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 SMART SM00830 9 89 2.2E-28 T 22-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 PANTHER PTHR21363 88 374 2.2E-66 T 22-04-2016 TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 SUPERFAMILY SSF51735 91 237 2.6E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 Gene3D G3DSA:1.10.3660.10 248 373 1.7E-51 T 22-04-2016 TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 PIRSF PIRSF001499 1 374 1.1E-172 T 22-04-2016 IPR008244 Bifunctional chorismate mutase/prephenate dehydrogenase T-protein GO:0004106|GO:0005737|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+5.4.99.5+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7303|MetaCyc: PWY-7626|UniPathway: UPA00120|UniPathway: UPA00122 TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 SUPERFAMILY SSF48179 241 365 3.74E-40 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS07030 a42effa6c826a452f2d963fe8a18ed71 375 Pfam PF01817 Chorismate mutase type II 9 86 9.1E-20 T 22-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 TOLA_RS10685 6e9e71f0e01ca06f06e5b060db19cd5b 342 PANTHER PTHR22572 60 294 6.0E-57 T 22-04-2016 TOLA_RS10685 6e9e71f0e01ca06f06e5b060db19cd5b 342 Gene3D G3DSA:2.160.10.10 98 138 2.0E-11 T 22-04-2016 TOLA_RS10685 6e9e71f0e01ca06f06e5b060db19cd5b 342 Gene3D G3DSA:2.160.10.10 139 308 3.4E-43 T 22-04-2016 TOLA_RS10685 6e9e71f0e01ca06f06e5b060db19cd5b 342 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 21 88 1.5E-22 T 22-04-2016 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 UniPathway: UPA00973 TOLA_RS10685 6e9e71f0e01ca06f06e5b060db19cd5b 342 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 7 328 1.9E-115 T 22-04-2016 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 UniPathway: UPA00973 TOLA_RS10685 6e9e71f0e01ca06f06e5b060db19cd5b 342 SUPERFAMILY SSF51161 31 315 1.62E-87 T 22-04-2016 IPR011004 Trimeric LpxA-like TOLA_RS10685 6e9e71f0e01ca06f06e5b060db19cd5b 342 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 8 325 35.621 T 22-04-2016 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 UniPathway: UPA00973 TOLA_RS10685 6e9e71f0e01ca06f06e5b060db19cd5b 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 145 178 6.1E-8 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS10685 6e9e71f0e01ca06f06e5b060db19cd5b 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 221 250 1.8E-4 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS10685 6e9e71f0e01ca06f06e5b060db19cd5b 342 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 109 143 3.6E-7 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS11870 2849b88414d860ddef57fcc24b6e3c63 203 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 1 203 25.147 T 22-04-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 TOLA_RS11870 2849b88414d860ddef57fcc24b6e3c63 203 PANTHER PTHR30586 1 203 5.4E-96 T 22-04-2016 TOLA_RS11870 2849b88414d860ddef57fcc24b6e3c63 203 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 5 201 3.3E-77 T 22-04-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 TOLA_RS11870 2849b88414d860ddef57fcc24b6e3c63 203 PIRSF PIRSF006102 1 203 4.6E-71 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 TOLA_RS11870 2849b88414d860ddef57fcc24b6e3c63 203 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 198 1.2E-61 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 TOLA_RS11870 2849b88414d860ddef57fcc24b6e3c63 203 PANTHER PTHR30586:SF0 1 203 5.4E-96 T 22-04-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 Pfam PF00575 S1 RNA binding domain 645 716 2.2E-20 T 22-04-2016 IPR003029 S1 domain GO:0003676 TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 SMART SM00316 645 716 4.2E-24 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 Pfam PF12836 Helix-hairpin-helix motif 487 551 3.7E-28 T 22-04-2016 TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 Gene3D G3DSA:1.10.3500.10 447 494 8.2E-100 T 22-04-2016 IPR023323 Tex-like domain TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 Gene3D G3DSA:1.10.3500.10 109 317 8.2E-100 T 22-04-2016 IPR023323 Tex-like domain TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 PANTHER PTHR10724 1 720 0.0 T 22-04-2016 TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 SUPERFAMILY SSF47781 466 554 2.78E-28 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 Gene3D G3DSA:2.40.50.140 629 716 7.8E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 PANTHER PTHR10724:SF1 1 720 0.0 T 22-04-2016 TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 SMART SM00732 321 420 1.4E-33 T 22-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 Gene3D G3DSA:3.30.420.140 321 446 3.3E-47 T 22-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 SUPERFAMILY SSF50249 633 721 4.62E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 Gene3D G3DSA:1.10.150.310 495 626 4.0E-47 T 22-04-2016 IPR023097 Tex RuvX-like domain TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 Gene3D G3DSA:1.10.10.650 3 108 1.6E-46 T 22-04-2016 IPR023319 Tex-like protein, HTH domain TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 SUPERFAMILY SSF47781 556 628 4.45E-20 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 Pfam PF16921 Tex protein YqgF-like domain 321 447 3.0E-50 T 22-04-2016 IPR032639 Tex protein, YqgF-like domain TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 SUPERFAMILY SSF53098 317 465 1.06E-48 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 Pfam PF09371 Tex-like protein N-terminal domain 8 192 1.2E-68 T 22-04-2016 IPR018974 Tex-like protein, N-terminal TOLA_RS02660 a63c78a5151df587c03ae3ca33a9fc6f 767 SUPERFAMILY SSF158832 2 316 4.58E-118 T 22-04-2016 TOLA_RS02190 3561119dbafcea286360b1f0781501c8 535 Pfam PF01293 Phosphoenolpyruvate carboxykinase 18 484 7.1E-209 T 22-04-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 TOLA_RS02190 3561119dbafcea286360b1f0781501c8 535 PIRSF PIRSF006294 3 534 5.2E-226 T 22-04-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 TOLA_RS02190 3561119dbafcea286360b1f0781501c8 535 Gene3D G3DSA:3.90.228.20 345 533 1.9E-119 T 22-04-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS02190 3561119dbafcea286360b1f0781501c8 535 Gene3D G3DSA:3.90.228.20 222 284 1.9E-119 T 22-04-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS02190 3561119dbafcea286360b1f0781501c8 535 Gene3D G3DSA:3.40.449.10 18 221 9.9E-85 T 22-04-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS02190 3561119dbafcea286360b1f0781501c8 535 SUPERFAMILY SSF68923 5 221 1.71E-87 T 22-04-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS02190 3561119dbafcea286360b1f0781501c8 535 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 259 274 - T 22-04-2016 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 TOLA_RS02190 3561119dbafcea286360b1f0781501c8 535 Hamap MF_00453 Phosphoenolpyruvate carboxykinase [ATP] [pckA]. 12 532 54.755 T 22-04-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 TOLA_RS02190 3561119dbafcea286360b1f0781501c8 535 PANTHER PTHR30031:SF0 10 535 0.0 T 22-04-2016 TOLA_RS02190 3561119dbafcea286360b1f0781501c8 535 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 7 534 7.1E-275 T 22-04-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 TOLA_RS02190 3561119dbafcea286360b1f0781501c8 535 SUPERFAMILY SSF53795 223 534 3.66E-130 T 22-04-2016 TOLA_RS02190 3561119dbafcea286360b1f0781501c8 535 PANTHER PTHR30031 10 535 0.0 T 22-04-2016 TOLA_RS12080 e62ef677b7797c407b896dda6b90f681 364 Pfam PF04632 Fusaric acid resistance protein family 22 258 1.0E-24 T 22-04-2016 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 TOLA_RS12080 e62ef677b7797c407b896dda6b90f681 364 PANTHER PTHR30509 6 257 3.0E-40 T 22-04-2016 TOLA_RS12080 e62ef677b7797c407b896dda6b90f681 364 PANTHER PTHR30509:SF3 6 257 3.0E-40 T 22-04-2016 TOLA_RS04830 97a15bb5db14ca52138498da27ccb9d7 460 Pfam PF00218 Indole-3-glycerol phosphate synthase 12 258 2.6E-95 T 22-04-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 TOLA_RS04830 97a15bb5db14ca52138498da27ccb9d7 460 PANTHER PTHR22854 9 288 2.4E-135 T 22-04-2016 TOLA_RS04830 97a15bb5db14ca52138498da27ccb9d7 460 SUPERFAMILY SSF51366 19 260 2.94E-82 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TOLA_RS04830 97a15bb5db14ca52138498da27ccb9d7 460 SUPERFAMILY SSF51366 262 458 5.34E-59 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TOLA_RS04830 97a15bb5db14ca52138498da27ccb9d7 460 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 22-04-2016 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 TOLA_RS04830 97a15bb5db14ca52138498da27ccb9d7 460 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 261 460 34.349 T 22-04-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24|UniPathway: UPA00035 TOLA_RS04830 97a15bb5db14ca52138498da27ccb9d7 460 Gene3D G3DSA:3.20.20.70 9 265 6.5E-101 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS04830 97a15bb5db14ca52138498da27ccb9d7 460 PANTHER PTHR22854:SF2 9 288 2.4E-135 T 22-04-2016 TOLA_RS04830 97a15bb5db14ca52138498da27ccb9d7 460 Gene3D G3DSA:3.20.20.70 266 458 2.1E-67 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS04830 97a15bb5db14ca52138498da27ccb9d7 460 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 10 260 35.209 T 22-04-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 TOLA_RS04830 97a15bb5db14ca52138498da27ccb9d7 460 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 263 454 9.2E-54 T 22-04-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24|UniPathway: UPA00035 TOLA_RS03655 7455a838311b80211fd0d736aa0b2524 256 SUPERFAMILY SSF51306 120 253 6.28E-23 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C TOLA_RS03655 7455a838311b80211fd0d736aa0b2524 256 Gene3D G3DSA:1.10.260.40 39 88 9.1E-5 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS03655 7455a838311b80211fd0d736aa0b2524 256 PANTHER PTHR40661 4 256 2.0E-54 T 22-04-2016 TOLA_RS03655 7455a838311b80211fd0d736aa0b2524 256 Gene3D G3DSA:2.10.109.10 122 255 2.3E-21 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain TOLA_RS03655 7455a838311b80211fd0d736aa0b2524 256 Pfam PF00717 Peptidase S24-like 169 235 2.3E-13 T 22-04-2016 IPR019759 Peptidase S24/S26A/S26B TOLA_RS04240 607f2a15800f1aba7e4a0f6e93e1ca2f 246 SUPERFAMILY SSF89550 5 242 1.96E-61 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 TOLA_RS04240 607f2a15800f1aba7e4a0f6e93e1ca2f 246 Gene3D G3DSA:3.20.20.140 3 236 4.6E-60 T 22-04-2016 TOLA_RS04240 607f2a15800f1aba7e4a0f6e93e1ca2f 246 SMART SM00481 5 79 1.1E-11 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 TOLA_RS04240 607f2a15800f1aba7e4a0f6e93e1ca2f 246 PANTHER PTHR36928 1 246 3.7E-102 T 22-04-2016 TOLA_RS04240 607f2a15800f1aba7e4a0f6e93e1ca2f 246 Pfam PF02811 PHP domain 6 82 3.1E-6 T 22-04-2016 IPR004013 PHP domain GO:0003824 TOLA_RS04240 607f2a15800f1aba7e4a0f6e93e1ca2f 246 Hamap MF_01561 Probable phosphatase YcdX [ycdX]. 2 244 50.414 T 22-04-2016 IPR023710 Probable phosphatase YcdX GO:0008270 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 PIRSF PIRSF000099 1 427 1.4E-163 T 22-04-2016 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 4 424 40.494 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 PANTHER PTHR21256 1 430 3.2E-260 T 22-04-2016 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 227 259 - T 22-04-2016 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 Gene3D G3DSA:3.40.50.620 236 304 2.6E-4 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS08825 94a527836493203a26915ced1644ff18 433 Pfam PF00815 Histidinol dehydrogenase 24 424 1.4E-167 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 423 5.5E-161 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 PRINTS PR00083 Histidinol dehydrogenase signature 165 191 3.81E-97 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 PRINTS PR00083 Histidinol dehydrogenase signature 195 220 3.81E-97 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 PRINTS PR00083 Histidinol dehydrogenase signature 249 268 3.81E-97 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 PRINTS PR00083 Histidinol dehydrogenase signature 134 160 3.81E-97 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 3.81E-97 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 PRINTS PR00083 Histidinol dehydrogenase signature 317 342 3.81E-97 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 PRINTS PR00083 Histidinol dehydrogenase signature 358 376 3.81E-97 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 PRINTS PR00083 Histidinol dehydrogenase signature 227 248 3.81E-97 T 22-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 PANTHER PTHR21256:SF14 1 430 3.2E-260 T 22-04-2016 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 SUPERFAMILY SSF53720 3 425 4.71E-85 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 TOLA_RS08825 94a527836493203a26915ced1644ff18 433 Gene3D G3DSA:3.40.50.1980 27 235 4.5E-79 T 22-04-2016 TOLA_RS09225 02adaa94750a6e8d38f50a5743df5d2e 102 Pfam PF11604 Copper binding periplasmic protein CusF 32 88 8.6E-13 T 22-04-2016 IPR021647 Copper binding periplasmic protein CusF TOLA_RS05915 affda26372b74079fb4b3080f5bf0254 513 Pfam PF12161 HsdM N-terminal domain 6 130 1.9E-12 T 22-04-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain TOLA_RS05915 affda26372b74079fb4b3080f5bf0254 513 Gene3D G3DSA:3.40.50.150 236 413 1.3E-41 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS05915 affda26372b74079fb4b3080f5bf0254 513 Gene3D G3DSA:3.40.50.150 163 204 1.3E-41 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS05915 affda26372b74079fb4b3080f5bf0254 513 Pfam PF02384 N-6 DNA Methylase 139 483 1.9E-60 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TOLA_RS05915 affda26372b74079fb4b3080f5bf0254 513 PANTHER PTHR30195:SF12 1 502 5.0E-149 T 22-04-2016 TOLA_RS05915 affda26372b74079fb4b3080f5bf0254 513 PANTHER PTHR30195 1 502 5.0E-149 T 22-04-2016 TOLA_RS05915 affda26372b74079fb4b3080f5bf0254 513 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 289 295 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TOLA_RS05915 affda26372b74079fb4b3080f5bf0254 513 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 160 176 2.7E-18 T 22-04-2016 TOLA_RS05915 affda26372b74079fb4b3080f5bf0254 513 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 286 298 2.7E-18 T 22-04-2016 TOLA_RS05915 affda26372b74079fb4b3080f5bf0254 513 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 184 198 2.7E-18 T 22-04-2016 TOLA_RS05915 affda26372b74079fb4b3080f5bf0254 513 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 316 340 2.7E-18 T 22-04-2016 TOLA_RS05915 affda26372b74079fb4b3080f5bf0254 513 SUPERFAMILY SSF53335 5 513 1.4E-114 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 298 2.3E-29 T 22-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 SMART SM00984 317 425 3.6E-16 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 SUPERFAMILY SSF52413 305 426 5.23E-22 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 PIRSF PIRSF500135 1 436 3.3E-211 T 22-04-2016 IPR028358 GDP-mannose 6-dehydrogenase GO:0042121|GO:0047919 KEGG: 00040+1.1.1.13|KEGG: 00051+1.1.1.132|KEGG: 00520+1.1.1.132|MetaCyc: PWY-6073|MetaCyc: PWY-6082|UniPathway: UPA00286 TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 Gene3D G3DSA:1.20.5.100 203 233 3.5E-12 T 22-04-2016 TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 189 3.7E-59 T 22-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 PIRSF PIRSF000124 1 436 2.0E-126 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 PANTHER PTHR11374:SF22 1 410 3.8E-209 T 22-04-2016 TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 420 4.7E-13 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 408 1.6E-127 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 Gene3D G3DSA:3.40.50.720 236 428 1.1E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 SUPERFAMILY SSF51735 1 197 1.08E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 PANTHER PTHR11374 1 410 3.8E-209 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 Gene3D G3DSA:3.40.50.720 1 194 5.7E-64 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS07190 52de8ef9a5889d4273c3f65d7f1d7eb0 436 SUPERFAMILY SSF48179 204 300 5.27E-28 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS01200 951d994305837e6913d8527a0d631bb0 439 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 436 1.4E-189 T 22-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 TOLA_RS01200 951d994305837e6913d8527a0d631bb0 439 Pfam PF02447 GntP family permease 1 435 2.3E-175 T 22-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 TOLA_RS01200 951d994305837e6913d8527a0d631bb0 439 PIRSF PIRSF002746 1 439 9.7E-156 T 22-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 TOLA_RS01200 951d994305837e6913d8527a0d631bb0 439 PANTHER PTHR30354 1 439 6.4E-220 T 22-04-2016 TOLA_RS01200 951d994305837e6913d8527a0d631bb0 439 PANTHER PTHR30354:SF1 1 439 6.4E-220 T 22-04-2016 TOLA_RS03340 6a25f0ff572f97243c7a1f5941dee4b7 166 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 22-04-2016 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 TOLA_RS03340 6a25f0ff572f97243c7a1f5941dee4b7 166 Gene3D G3DSA:3.40.30.10 2 165 5.7E-44 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS03340 6a25f0ff572f97243c7a1f5941dee4b7 166 Pfam PF08534 Redoxin 19 162 2.2E-25 T 22-04-2016 IPR013740 Redoxin GO:0016491 TOLA_RS03340 6a25f0ff572f97243c7a1f5941dee4b7 166 PANTHER PTHR10681:SF81 3 165 8.3E-50 T 22-04-2016 TOLA_RS03340 6a25f0ff572f97243c7a1f5941dee4b7 166 PANTHER PTHR10681 3 165 8.3E-50 T 22-04-2016 TOLA_RS03340 6a25f0ff572f97243c7a1f5941dee4b7 166 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 166 38.266 T 22-04-2016 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 TOLA_RS03340 6a25f0ff572f97243c7a1f5941dee4b7 166 SUPERFAMILY SSF52833 1 163 6.83E-43 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS12490 18c3c6ffabeaf6afa1dd6248fd6ccdcd 618 TIGRFAM TIGR03760 ICE_TraI_Pfluor: integrating conjugative element relaxase, PFGI-1 class 26 243 8.0E-90 T 22-04-2016 IPR022391 Integrating conjugative element relaxase, PFGI-1 class TOLA_RS12490 18c3c6ffabeaf6afa1dd6248fd6ccdcd 618 Gene3D G3DSA:2.40.10.200 503 524 2.2E-9 T 22-04-2016 TOLA_RS12490 18c3c6ffabeaf6afa1dd6248fd6ccdcd 618 Gene3D G3DSA:2.40.10.200 559 609 2.2E-9 T 22-04-2016 TOLA_RS12490 18c3c6ffabeaf6afa1dd6248fd6ccdcd 618 Pfam PF07514 Putative helicase 27 340 1.0E-125 T 22-04-2016 IPR011119 Uncharacterised domain, helicase/relaxase, putative TOLA_RS12490 18c3c6ffabeaf6afa1dd6248fd6ccdcd 618 Pfam PF07515 Putative conjugal transfer nickase/helicase TraI C-term 486 609 1.2E-49 T 22-04-2016 IPR011093 Putative conjugal transfer nickase/helicase TraI, C-terminal TOLA_RS12490 18c3c6ffabeaf6afa1dd6248fd6ccdcd 618 SUPERFAMILY SSF46785 483 609 1.31E-43 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15465 2380fe189459558ab66450d2eab345e8 226 Pfam PF00005 ABC transporter 18 165 9.0E-34 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS15465 2380fe189459558ab66450d2eab345e8 226 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 6.1E-86 T 22-04-2016 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 TOLA_RS15465 2380fe189459558ab66450d2eab345e8 226 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS15465 2380fe189459558ab66450d2eab345e8 226 PANTHER PTHR24220:SF470 3 218 4.1E-115 T 22-04-2016 TOLA_RS15465 2380fe189459558ab66450d2eab345e8 226 PANTHER PTHR24220 3 218 4.1E-115 T 22-04-2016 TOLA_RS15465 2380fe189459558ab66450d2eab345e8 226 SUPERFAMILY SSF52540 1 219 2.59E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15465 2380fe189459558ab66450d2eab345e8 226 SMART SM00382 27 214 4.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS15465 2380fe189459558ab66450d2eab345e8 226 Gene3D G3DSA:3.40.50.300 1 218 2.9E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03915 5615f6d99f28d4e695ffdd9234bc13aa 276 SUPERFAMILY SSF56112 10 249 2.55E-31 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS03915 5615f6d99f28d4e695ffdd9234bc13aa 276 Gene3D G3DSA:3.90.1200.10 61 225 2.5E-15 T 22-04-2016 TOLA_RS03915 5615f6d99f28d4e695ffdd9234bc13aa 276 Pfam PF01636 Phosphotransferase enzyme family 15 218 1.1E-17 T 22-04-2016 IPR002575 Aminoglycoside phosphotransferase TOLA_RS06780 e7ea738b5cde684e2ddedd63b9b39f73 584 SUPERFAMILY SSF53474 63 581 1.01E-120 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS06780 e7ea738b5cde684e2ddedd63b9b39f73 584 PANTHER PTHR11559 8 582 6.4E-155 T 22-04-2016 TOLA_RS06780 e7ea738b5cde684e2ddedd63b9b39f73 584 Pfam PF00135 Carboxylesterase family 63 578 4.6E-121 T 22-04-2016 IPR002018 Carboxylesterase, type B TOLA_RS06780 e7ea738b5cde684e2ddedd63b9b39f73 584 Gene3D G3DSA:3.40.50.1820 61 582 1.3E-144 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS06780 e7ea738b5cde684e2ddedd63b9b39f73 584 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 235 250 - T 22-04-2016 IPR019826 Carboxylesterase type B, active site TOLA_RS06150 aa92da730fb45c83b763a431efd9ae75 364 Gene3D G3DSA:1.10.10.60 265 359 7.6E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS06150 aa92da730fb45c83b763a431efd9ae75 364 Gene3D G3DSA:3.40.50.300 38 213 4.0E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06150 aa92da730fb45c83b763a431efd9ae75 364 Gene3D G3DSA:1.10.8.60 214 264 1.1E-20 T 22-04-2016 TOLA_RS06150 aa92da730fb45c83b763a431efd9ae75 364 PANTHER PTHR32071:SF18 9 364 3.8E-102 T 22-04-2016 TOLA_RS06150 aa92da730fb45c83b763a431efd9ae75 364 Pfam PF00158 Sigma-54 interaction domain 41 207 1.7E-46 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TOLA_RS06150 aa92da730fb45c83b763a431efd9ae75 364 SUPERFAMILY SSF46689 309 359 2.6E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS06150 aa92da730fb45c83b763a431efd9ae75 364 Pfam PF02954 Bacterial regulatory protein, Fis family 318 357 7.5E-14 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS06150 aa92da730fb45c83b763a431efd9ae75 364 PANTHER PTHR32071 9 364 3.8E-102 T 22-04-2016 TOLA_RS06150 aa92da730fb45c83b763a431efd9ae75 364 SMART SM00382 61 203 5.1E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS06150 aa92da730fb45c83b763a431efd9ae75 364 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 323 340 1.2E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS06150 aa92da730fb45c83b763a431efd9ae75 364 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 340 360 1.2E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS06150 aa92da730fb45c83b763a431efd9ae75 364 SUPERFAMILY SSF52540 41 277 1.61E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11840 6b0d32047194c3554c3fb04671543fcb 508 TIGRFAM TIGR02938 nifL_nitrog: nitrogen fixation negative regulator NifL 29 498 1.8E-96 T 22-04-2016 IPR014285 Nitrogen fixation negative regulator NifL GO:0004871|GO:0007165|GO:0009399|GO:0050660 TOLA_RS11840 6b0d32047194c3554c3fb04671543fcb 508 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 33 152 2.3E-20 T 22-04-2016 IPR000014 PAS domain TOLA_RS11840 6b0d32047194c3554c3fb04671543fcb 508 PANTHER PTHR24423 31 499 3.0E-21 T 22-04-2016 TOLA_RS11840 6b0d32047194c3554c3fb04671543fcb 508 Pfam PF00989 PAS fold 35 143 4.3E-20 T 22-04-2016 IPR013767 PAS fold GO:0006355 TOLA_RS11840 6b0d32047194c3554c3fb04671543fcb 508 SUPERFAMILY SSF55874 355 499 6.32E-10 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS11840 6b0d32047194c3554c3fb04671543fcb 508 Gene3D G3DSA:3.30.565.10 355 499 1.0E-9 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS11840 6b0d32047194c3554c3fb04671543fcb 508 SMART SM00091 32 99 5.5E-4 T 22-04-2016 IPR000014 PAS domain TOLA_RS11840 6b0d32047194c3554c3fb04671543fcb 508 SUPERFAMILY SSF55785 40 143 4.71E-28 T 22-04-2016 IPR000014 PAS domain TOLA_RS11840 6b0d32047194c3554c3fb04671543fcb 508 Gene3D G3DSA:3.30.450.20 41 146 7.9E-27 T 22-04-2016 TOLA_RS11840 6b0d32047194c3554c3fb04671543fcb 508 SMART SM00086 104 146 4.3E-10 T 22-04-2016 IPR001610 PAC motif TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 SUPERFAMILY SSF46609 1 84 1.24E-34 T 22-04-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 PANTHER PTHR11404:SF8 1 193 2.7E-109 T 22-04-2016 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 82 2.6E-34 T 22-04-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 PANTHER PTHR11404 1 193 2.7E-109 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 Gene3D G3DSA:1.10.287.990 20 82 1.5E-24 T 22-04-2016 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 PIRSF PIRSF000349 1 193 3.5E-84 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 SUPERFAMILY SSF54719 82 192 1.03E-44 T 22-04-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 2.9E-21 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 2.9E-21 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 2.9E-21 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 2.9E-21 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 2.9E-21 T 22-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 1.5E-38 T 22-04-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 TOLA_RS11295 c70a290b3f0510d7819ca10536d33bdb 193 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 22-04-2016 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 TOLA_RS11210 756616791bea27a207c17180e722781f 555 PANTHER PTHR11772 2 539 7.6E-287 T 22-04-2016 TOLA_RS11210 756616791bea27a207c17180e722781f 555 Gene3D G3DSA:3.40.50.620 194 511 5.4E-117 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS11210 756616791bea27a207c17180e722781f 555 Pfam PF13537 Glutamine amidotransferase domain 48 166 1.0E-38 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain TOLA_RS11210 756616791bea27a207c17180e722781f 555 SUPERFAMILY SSF56235 1 193 3.6E-55 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS11210 756616791bea27a207c17180e722781f 555 SUPERFAMILY SSF52402 212 479 4.68E-76 T 22-04-2016 TOLA_RS11210 756616791bea27a207c17180e722781f 555 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 374 1.8E-119 T 22-04-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|UniPathway: UPA00134 TOLA_RS11210 756616791bea27a207c17180e722781f 555 Pfam PF00733 Asparagine synthase 368 512 1.5E-41 T 22-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TOLA_RS11210 756616791bea27a207c17180e722781f 555 Pfam PF00733 Asparagine synthase 213 367 7.4E-57 T 22-04-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TOLA_RS11210 756616791bea27a207c17180e722781f 555 PANTHER PTHR11772:SF11 2 539 7.6E-287 T 22-04-2016 TOLA_RS11210 756616791bea27a207c17180e722781f 555 Gene3D G3DSA:3.60.20.10 1 193 1.4E-65 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 SUPERFAMILY SSF55073 260 410 6.43E-37 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 Gene3D G3DSA:3.40.50.2300 2 118 3.6E-10 T 22-04-2016 TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 SUPERFAMILY SSF52172 125 260 6.26E-30 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 SMART SM00448 124 238 1.4E-24 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 SMART SM00448 2 115 0.036 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 PANTHER PTHR26402 124 235 3.2E-28 T 22-04-2016 TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 Gene3D G3DSA:3.40.50.2300 124 245 1.3E-28 T 22-04-2016 TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 Pfam PF00990 Diguanylate cyclase, GGDEF domain 256 408 6.0E-34 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 Pfam PF00072 Response regulator receiver domain 126 238 1.1E-19 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 Gene3D G3DSA:3.30.70.270 256 411 1.2E-41 T 22-04-2016 TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 SMART SM00267 244 412 1.8E-38 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 255 410 3.3E-38 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS08860 2a0cdaa51a404f95ffae4115a36fb237 414 SUPERFAMILY SSF52172 2 118 1.25E-10 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 SUPERFAMILY SSF52374 1 312 5.9E-101 T 22-04-2016 TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 1.5E-29 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 1.5E-29 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 1.5E-29 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 1.5E-29 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 SMART SM00840 342 403 2.4E-29 T 22-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 462 39.274 T 22-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 461 2.4E-185 T 22-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 Pfam PF09190 DALR domain 342 403 1.7E-24 T 22-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 PANTHER PTHR10890 1 461 1.0E-259 T 22-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 Gene3D G3DSA:1.20.120.640 308 393 2.2E-27 T 22-04-2016 TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 Gene3D G3DSA:3.40.50.620 19 305 2.3E-112 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 SUPERFAMILY SSF47323 316 461 4.05E-42 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS09770 974d05900725d35c15d33f2a2d941ff3 463 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 313 7.0E-137 T 22-04-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TOLA_RS03570 883d5880015cf54a4400c56a55a0ae4b 141 SUPERFAMILY SSF51316 2 92 1.36E-14 T 22-04-2016 IPR011057 Mss4-like TOLA_RS03570 883d5880015cf54a4400c56a55a0ae4b 141 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 32 107 3.8E-5 T 22-04-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 TOLA_RS03570 883d5880015cf54a4400c56a55a0ae4b 141 PANTHER PTHR28620:SF2 7 106 2.7E-12 T 22-04-2016 TOLA_RS03570 883d5880015cf54a4400c56a55a0ae4b 141 Gene3D G3DSA:3.90.1590.10 5 96 2.2E-12 T 22-04-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 TOLA_RS03570 883d5880015cf54a4400c56a55a0ae4b 141 PANTHER PTHR28620 7 106 2.7E-12 T 22-04-2016 TOLA_RS09120 9d1f989d045f1c0e8f3270d7f82e3f90 215 Pfam PF01081 KDPG and KHG aldolase 12 202 1.5E-77 T 22-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TOLA_RS09120 9d1f989d045f1c0e8f3270d7f82e3f90 215 PANTHER PTHR30246 1 215 3.0E-111 T 22-04-2016 TOLA_RS09120 9d1f989d045f1c0e8f3270d7f82e3f90 215 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 39 48 - T 22-04-2016 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562|UniPathway: UPA00227|UniPathway: UPA00856 TOLA_RS09120 9d1f989d045f1c0e8f3270d7f82e3f90 215 Gene3D G3DSA:3.20.20.70 7 214 6.5E-82 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS09120 9d1f989d045f1c0e8f3270d7f82e3f90 215 SUPERFAMILY SSF51569 6 211 2.01E-71 T 22-04-2016 TOLA_RS09120 9d1f989d045f1c0e8f3270d7f82e3f90 215 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 127 140 - T 22-04-2016 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TOLA_RS09120 9d1f989d045f1c0e8f3270d7f82e3f90 215 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 209 1.6E-80 T 22-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TOLA_RS09120 9d1f989d045f1c0e8f3270d7f82e3f90 215 PANTHER PTHR30246:SF0 1 215 3.0E-111 T 22-04-2016 TOLA_RS10875 94f2ee89e2e3c25ccd81cdeb2e678a68 285 Gene3D G3DSA:1.10.10.10 1 81 2.4E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10875 94f2ee89e2e3c25ccd81cdeb2e678a68 285 Gene3D G3DSA:3.40.190.10 119 177 1.9E-6 T 22-04-2016 TOLA_RS10875 94f2ee89e2e3c25ccd81cdeb2e678a68 285 PANTHER PTHR30126 1 271 7.5E-85 T 22-04-2016 TOLA_RS10875 94f2ee89e2e3c25ccd81cdeb2e678a68 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.2E-10 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10875 94f2ee89e2e3c25ccd81cdeb2e678a68 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.2E-10 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10875 94f2ee89e2e3c25ccd81cdeb2e678a68 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.2E-10 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10875 94f2ee89e2e3c25ccd81cdeb2e678a68 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.8E-18 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10875 94f2ee89e2e3c25ccd81cdeb2e678a68 285 SUPERFAMILY SSF53850 84 275 6.15E-18 T 22-04-2016 TOLA_RS10875 94f2ee89e2e3c25ccd81cdeb2e678a68 285 PANTHER PTHR30126:SF21 1 271 7.5E-85 T 22-04-2016 TOLA_RS10875 94f2ee89e2e3c25ccd81cdeb2e678a68 285 Pfam PF03466 LysR substrate binding domain 88 274 5.0E-19 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS10875 94f2ee89e2e3c25ccd81cdeb2e678a68 285 SUPERFAMILY SSF46785 1 82 4.49E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 8 551 6.0E-258 T 22-04-2016 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 PANTHER PTHR10357:SF170 453 531 4.8E-257 T 22-04-2016 TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 PANTHER PTHR10357:SF170 1 421 4.8E-257 T 22-04-2016 TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 Gene3D G3DSA:2.60.40.1180 478 552 2.5E-15 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 SMART SM00642 16 416 2.1E-155 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 Pfam PF00128 Alpha amylase, catalytic domain 31 374 2.4E-126 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 Gene3D G3DSA:3.90.400.10 108 177 2.9E-29 T 22-04-2016 TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 Pfam PF11941 Domain of unknown function (DUF3459) 460 551 7.9E-6 T 22-04-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 SUPERFAMILY SSF51011 477 552 2.7E-12 T 22-04-2016 TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 PANTHER PTHR10357 453 531 4.8E-257 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 PANTHER PTHR10357 1 421 4.8E-257 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 SUPERFAMILY SSF51445 4 474 9.06E-156 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 Gene3D G3DSA:3.20.20.80 4 107 2.0E-124 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS00880 1ec98546b1ab84f24f247f57bc8bce4c 554 Gene3D G3DSA:3.20.20.80 178 475 2.0E-124 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS01445 716c4c3f30725b214a26a3dba2f33cf6 571 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 71 232 2.1E-19 T 22-04-2016 TOLA_RS01445 716c4c3f30725b214a26a3dba2f33cf6 571 PANTHER PTHR33908 1 502 6.1E-89 T 22-04-2016 TOLA_RS01445 716c4c3f30725b214a26a3dba2f33cf6 571 PANTHER PTHR33908:SF3 1 502 6.1E-89 T 22-04-2016 TOLA_RS16105 38c6e0524e8bf023ec3c681651ab8539 259 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 23 254 1.7E-41 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 TOLA_RS16105 38c6e0524e8bf023ec3c681651ab8539 259 Pfam PF00119 ATP synthase A chain 35 253 2.8E-55 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 TOLA_RS16105 38c6e0524e8bf023ec3c681651ab8539 259 PANTHER PTHR11410 26 259 7.0E-98 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 TOLA_RS16105 38c6e0524e8bf023ec3c681651ab8539 259 SUPERFAMILY SSF81336 84 253 6.54E-47 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 TOLA_RS16105 38c6e0524e8bf023ec3c681651ab8539 259 Gene3D G3DSA:1.20.120.220 85 259 9.5E-58 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 TOLA_RS16105 38c6e0524e8bf023ec3c681651ab8539 259 Hamap MF_01393 ATP synthase subunit a [atpB]. 10 259 15.808 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 TOLA_RS16105 38c6e0524e8bf023ec3c681651ab8539 259 ProSitePatterns PS00449 ATP synthase a subunit signature. 194 203 - T 22-04-2016 IPR023011 ATPase, F0 complex, subunit A, active site TOLA_RS16105 38c6e0524e8bf023ec3c681651ab8539 259 PRINTS PR00123 ATP synthase A subunit signature 239 254 1.7E-14 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 TOLA_RS16105 38c6e0524e8bf023ec3c681651ab8539 259 PRINTS PR00123 ATP synthase A subunit signature 93 109 1.7E-14 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 TOLA_RS16105 38c6e0524e8bf023ec3c681651ab8539 259 PRINTS PR00123 ATP synthase A subunit signature 191 213 1.7E-14 T 22-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 TOLA_RS16105 38c6e0524e8bf023ec3c681651ab8539 259 PANTHER PTHR11410:SF7 26 259 7.0E-98 T 22-04-2016 TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 Pfam PF12833 Helix-turn-helix domain 204 281 1.9E-20 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 265 281 2.8E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 250 265 2.8E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 PANTHER PTHR11019 39 281 3.7E-55 T 22-04-2016 TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 Gene3D G3DSA:1.10.10.60 235 281 1.5E-15 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 PANTHER PTHR11019:SF11 39 281 3.7E-55 T 22-04-2016 TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 Gene3D G3DSA:1.10.10.60 178 234 1.0E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 SMART SM00342 198 281 4.2E-30 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 235 277 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 SUPERFAMILY SSF46689 183 231 4.12E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 SUPERFAMILY SSF51182 194 224 4.02E-5 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 SUPERFAMILY SSF51182 47 114 4.02E-5 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS02325 bed195502e9560498d7cd1aec857b9ea 284 SUPERFAMILY SSF46689 234 281 5.82E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS16355 41e8361ac0e5548ca11a8afdb288c0e2 233 PRINTS PR01374 Gram-negative bacterial tonB protein signature 170 188 1.2E-8 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 TOLA_RS16355 41e8361ac0e5548ca11a8afdb288c0e2 233 PRINTS PR01374 Gram-negative bacterial tonB protein signature 93 103 1.2E-8 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 TOLA_RS16355 41e8361ac0e5548ca11a8afdb288c0e2 233 PRINTS PR01374 Gram-negative bacterial tonB protein signature 149 170 1.2E-8 T 22-04-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 TOLA_RS16355 41e8361ac0e5548ca11a8afdb288c0e2 233 Gene3D G3DSA:3.30.1150.10 152 232 7.7E-16 T 22-04-2016 TOLA_RS16355 41e8361ac0e5548ca11a8afdb288c0e2 233 SUPERFAMILY SSF74653 148 229 2.62E-22 T 22-04-2016 TOLA_RS16355 41e8361ac0e5548ca11a8afdb288c0e2 233 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 153 231 5.1E-21 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 TOLA_RS16355 41e8361ac0e5548ca11a8afdb288c0e2 233 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 155 231 1.1E-20 T 22-04-2016 IPR006260 TonB, C-terminal GO:0006810 TOLA_RS05300 5f40a62900c33439b1c4859ed0c71410 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.9E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS05300 5f40a62900c33439b1c4859ed0c71410 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.9E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS05300 5f40a62900c33439b1c4859ed0c71410 199 PANTHER PTHR30055 1 199 2.3E-61 T 22-04-2016 TOLA_RS05300 5f40a62900c33439b1c4859ed0c71410 199 PANTHER PTHR30055:SF76 1 199 2.3E-61 T 22-04-2016 TOLA_RS05300 5f40a62900c33439b1c4859ed0c71410 199 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 145 197 2.4E-5 T 22-04-2016 TOLA_RS05300 5f40a62900c33439b1c4859ed0c71410 199 Gene3D G3DSA:1.10.357.10 54 199 1.8E-31 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 TOLA_RS05300 5f40a62900c33439b1c4859ed0c71410 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 6.9E-17 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS05300 5f40a62900c33439b1c4859ed0c71410 199 Gene3D G3DSA:1.10.10.60 1 53 1.1E-22 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS05300 5f40a62900c33439b1c4859ed0c71410 199 SUPERFAMILY SSF46689 1 81 2.1E-20 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS14510 d0bebd311aa04cf6259e810003151b0a 256 PANTHER PTHR34183 30 194 2.7E-62 T 22-04-2016 TOLA_RS14510 d0bebd311aa04cf6259e810003151b0a 256 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 80 246 6.7E-44 T 22-04-2016 IPR012997 Rare lipoprotein A TOLA_RS14510 d0bebd311aa04cf6259e810003151b0a 256 Pfam PF03330 Lytic transglycolase 78 166 2.5E-22 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain TOLA_RS14510 d0bebd311aa04cf6259e810003151b0a 256 SUPERFAMILY SSF50685 73 169 1.78E-11 T 22-04-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain TOLA_RS14510 d0bebd311aa04cf6259e810003151b0a 256 SUPERFAMILY SSF110997 188 254 8.24E-8 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 TOLA_RS14510 d0bebd311aa04cf6259e810003151b0a 256 PANTHER PTHR34183:SF1 30 194 2.7E-62 T 22-04-2016 TOLA_RS14510 d0bebd311aa04cf6259e810003151b0a 256 Gene3D G3DSA:3.30.70.1070 186 253 8.1E-6 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 TOLA_RS14510 d0bebd311aa04cf6259e810003151b0a 256 Pfam PF05036 Sporulation related domain 189 254 6.1E-7 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 TOLA_RS09890 2d22c8b6eef649893ebc1b2ee6da169b 327 Pfam PF01261 Xylose isomerase-like TIM barrel 42 232 5.7E-14 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS09890 2d22c8b6eef649893ebc1b2ee6da169b 327 Gene3D G3DSA:3.20.20.150 37 325 4.4E-75 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS09890 2d22c8b6eef649893ebc1b2ee6da169b 327 SUPERFAMILY SSF51658 3 325 1.3E-75 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937:SF201 444 499 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937:SF201 846 877 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937:SF201 987 1122 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937:SF201 1432 1465 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937:SF201 99 426 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937:SF201 566 820 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937:SF201 896 944 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937:SF201 521 550 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937:SF201 1218 1254 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 Gene3D G3DSA:3.40.1140.10 3 226 2.0E-38 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 SUPERFAMILY SSF52540 8 224 1.09E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1342 1430 1.2E-14 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937 444 499 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937 846 877 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937 987 1122 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937 1432 1465 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937 99 426 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937 566 820 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937 896 944 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937 521 550 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 PANTHER PTHR18937 1218 1254 1.4E-145 T 22-04-2016 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 Pfam PF04310 MukB N-terminal 2 227 1.0E-120 T 22-04-2016 IPR007406 MukB, N-terminal domain GO:0003677|GO:0005524|GO:0007059|GO:0009295|GO:0030261 TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 SUPERFAMILY SSF52540 22 55 7.06E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 SUPERFAMILY SSF52540 1274 1438 7.06E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07460 9324fc87a044af536db698b8859dbd77 1480 Pfam PF16330 MukB hinge domain 650 816 4.9E-67 T 22-04-2016 IPR032520 MukB, hinge domain TOLA_RS02500 97620bb6345e3fc0a5181eda5387a519 414 Gene3D G3DSA:3.40.50.10380 8 160 2.5E-46 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TOLA_RS02500 97620bb6345e3fc0a5181eda5387a519 414 Gene3D G3DSA:3.40.50.720 161 411 1.8E-82 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS02500 97620bb6345e3fc0a5181eda5387a519 414 SUPERFAMILY SSF53223 10 161 2.88E-50 T 22-04-2016 TOLA_RS02500 97620bb6345e3fc0a5181eda5387a519 414 SMART SM01274 18 151 4.1E-74 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TOLA_RS02500 97620bb6345e3fc0a5181eda5387a519 414 PANTHER PTHR23406 33 407 6.1E-152 T 22-04-2016 TOLA_RS02500 97620bb6345e3fc0a5181eda5387a519 414 ProSitePatterns PS00331 Malic enzymes signature. 159 175 - T 22-04-2016 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 TOLA_RS02500 97620bb6345e3fc0a5181eda5387a519 414 Pfam PF03949 Malic enzyme, NAD binding domain 165 357 6.8E-24 T 22-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 TOLA_RS02500 97620bb6345e3fc0a5181eda5387a519 414 SUPERFAMILY SSF51735 163 411 4.48E-79 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS02500 97620bb6345e3fc0a5181eda5387a519 414 Pfam PF00390 Malic enzyme, N-terminal domain 117 149 1.2E-4 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TOLA_RS02500 97620bb6345e3fc0a5181eda5387a519 414 Pfam PF00390 Malic enzyme, N-terminal domain 20 112 2.4E-21 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TOLA_RS02500 97620bb6345e3fc0a5181eda5387a519 414 SMART SM00919 163 399 2.2E-129 T 22-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 TOLA_RS07585 3907f2c2079f67ff5953f616341d507f 725 SUPERFAMILY SSF56935 32 725 4.58E-94 T 22-04-2016 TOLA_RS07585 3907f2c2079f67ff5953f616341d507f 725 PANTHER PTHR32552 71 725 5.5E-209 T 22-04-2016 TOLA_RS07585 3907f2c2079f67ff5953f616341d507f 725 PANTHER PTHR32552 24 45 5.5E-209 T 22-04-2016 TOLA_RS07585 3907f2c2079f67ff5953f616341d507f 725 Gene3D G3DSA:2.170.130.10 32 191 1.2E-19 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 TOLA_RS07585 3907f2c2079f67ff5953f616341d507f 725 Pfam PF07715 TonB-dependent Receptor Plug Domain 80 171 4.9E-8 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 TOLA_RS07585 3907f2c2079f67ff5953f616341d507f 725 PANTHER PTHR32552:SF14 71 725 5.5E-209 T 22-04-2016 IPR030149 TonB-dependent siderophore receptor FcuA/FatA GO:0004872|GO:0005506|GO:0009279|GO:0015891|GO:0016021 TOLA_RS07585 3907f2c2079f67ff5953f616341d507f 725 PANTHER PTHR32552:SF14 24 45 5.5E-209 T 22-04-2016 IPR030149 TonB-dependent siderophore receptor FcuA/FatA GO:0004872|GO:0005506|GO:0009279|GO:0015891|GO:0016021 TOLA_RS07585 3907f2c2079f67ff5953f616341d507f 725 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 81 725 1.2E-104 T 22-04-2016 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 TOLA_RS07585 3907f2c2079f67ff5953f616341d507f 725 Gene3D G3DSA:2.40.170.20 196 725 1.3E-94 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 TOLA_RS07585 3907f2c2079f67ff5953f616341d507f 725 Pfam PF00593 TonB dependent receptor 474 721 2.0E-23 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 TOLA_RS01365 f13d6aacf2b7ea5271e08dbb15f39e7c 1272 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 15 1259 4.5E-237 T 22-04-2016 IPR011836 Conserved hypothetical protein CHP02099 TOLA_RS01365 f13d6aacf2b7ea5271e08dbb15f39e7c 1272 Pfam PF13116 Protein of unknown function 500 777 9.6E-75 T 22-04-2016 IPR025263 Domain of unknown function DUF3971 TOLA_RS01365 f13d6aacf2b7ea5271e08dbb15f39e7c 1272 PANTHER PTHR38690 1 1269 1.8E-205 T 22-04-2016 TOLA_RS01365 f13d6aacf2b7ea5271e08dbb15f39e7c 1272 Pfam PF13502 AsmA-like C-terminal region 1007 1249 1.9E-52 T 22-04-2016 IPR032712 AsmA-like, C-terminal TOLA_RS09705 aefe7f28ce13863342bf7287d62f441e 394 SUPERFAMILY SSF56349 84 372 4.41E-48 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TOLA_RS09705 aefe7f28ce13863342bf7287d62f441e 394 Gene3D G3DSA:1.10.443.10 196 371 4.1E-29 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS09705 aefe7f28ce13863342bf7287d62f441e 394 Pfam PF12167 Domain of unknown function (DUF3596) 1 64 2.0E-19 T 22-04-2016 IPR022000 Domain of unknown function (DUF3596) TOLA_RS09705 aefe7f28ce13863342bf7287d62f441e 394 Pfam PF00589 Phage integrase family 199 366 1.2E-14 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS09705 aefe7f28ce13863342bf7287d62f441e 394 PANTHER PTHR30349 88 372 3.2E-18 T 22-04-2016 TOLA_RS09705 aefe7f28ce13863342bf7287d62f441e 394 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 86 140 2.5E-6 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TOLA_RS09705 aefe7f28ce13863342bf7287d62f441e 394 Gene3D G3DSA:1.10.150.130 85 173 2.9E-6 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 Gene3D G3DSA:3.40.50.880 154 375 3.9E-82 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 PRINTS PR00096 Glutamine amidotransferase superfamily signature 233 242 4.1E-11 T 22-04-2016 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 PRINTS PR00096 Glutamine amidotransferase superfamily signature 346 359 4.1E-11 T 22-04-2016 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 PRINTS PR00096 Glutamine amidotransferase superfamily signature 261 272 4.1E-11 T 22-04-2016 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 SUPERFAMILY SSF52317 153 375 5.35E-62 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 278 295 1.4E-40 T 22-04-2016 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 303 314 1.4E-40 T 22-04-2016 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 191 205 1.4E-40 T 22-04-2016 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 230 244 1.4E-40 T 22-04-2016 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 261 277 1.4E-40 T 22-04-2016 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 375 48.496 T 22-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 Pfam PF00117 Glutamine amidotransferase class-I 194 369 7.8E-48 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 SMART SM01097 3 133 5.3E-92 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 Gene3D G3DSA:3.50.30.20 4 142 5.3E-62 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 PANTHER PTHR11405 4 376 1.0E-250 T 22-04-2016 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 132 1.3E-52 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 PRINTS PR00097 Anthranilate synthase component II signature 233 242 1.5E-5 T 22-04-2016 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 PRINTS PR00097 Anthranilate synthase component II signature 346 359 1.5E-5 T 22-04-2016 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 PRINTS PR00097 Anthranilate synthase component II signature 261 272 1.5E-5 T 22-04-2016 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 SUPERFAMILY SSF52021 4 141 9.29E-58 T 22-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS05280 bf796559de12262206c6a399cad3e790 376 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 372 4.8E-148 T 22-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 121 6.3E-22 T 22-04-2016 IPR000014 PAS domain TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 SUPERFAMILY SSF55073 293 441 2.75E-46 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 SMART SM00065 139 285 3.7E-10 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 Pfam PF08447 PAS fold 30 101 2.2E-13 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 Gene3D G3DSA:3.30.70.270 290 442 2.1E-50 T 22-04-2016 TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 Gene3D G3DSA:3.30.450.40 120 284 6.8E-21 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 SMART SM00267 277 448 3.0E-54 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 Pfam PF13185 GAF domain 140 276 1.6E-8 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 SUPERFAMILY SSF55781 125 288 3.05E-21 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 Pfam PF00990 Diguanylate cyclase, GGDEF domain 288 442 1.3E-46 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 284 444 2.7E-42 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 PANTHER PTHR10799 192 441 2.4E-40 T 22-04-2016 TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 SMART SM00091 7 73 8.3E-8 T 22-04-2016 IPR000014 PAS domain TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 SUPERFAMILY SSF55785 18 121 3.08E-25 T 22-04-2016 IPR000014 PAS domain TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 PANTHER PTHR10799:SF774 192 441 2.4E-40 T 22-04-2016 TOLA_RS09935 93af82426cf582af0eeace74612c8881 451 Gene3D G3DSA:3.30.450.20 16 119 1.1E-24 T 22-04-2016 TOLA_RS05610 d8127bbb5d2e7339fc1cb8c8d25ee900 427 Pfam PF00202 Aminotransferase class-III 25 415 7.1E-132 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS05610 d8127bbb5d2e7339fc1cb8c8d25ee900 427 Gene3D G3DSA:3.40.640.10 60 325 3.3E-94 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS05610 d8127bbb5d2e7339fc1cb8c8d25ee900 427 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 11 415 3.5E-186 T 22-04-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62|UniPathway: UPA00078 TOLA_RS05610 d8127bbb5d2e7339fc1cb8c8d25ee900 427 PANTHER PTHR11986:SF8 4 427 1.7E-214 T 22-04-2016 TOLA_RS05610 d8127bbb5d2e7339fc1cb8c8d25ee900 427 SUPERFAMILY SSF53383 4 416 6.05E-134 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS05610 d8127bbb5d2e7339fc1cb8c8d25ee900 427 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 277 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS05610 d8127bbb5d2e7339fc1cb8c8d25ee900 427 PANTHER PTHR11986 4 427 1.7E-214 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS05610 d8127bbb5d2e7339fc1cb8c8d25ee900 427 Gene3D G3DSA:3.90.1150.10 330 420 9.1E-57 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS05610 d8127bbb5d2e7339fc1cb8c8d25ee900 427 Gene3D G3DSA:3.90.1150.10 4 59 9.1E-57 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS05610 d8127bbb5d2e7339fc1cb8c8d25ee900 427 PIRSF PIRSF000521 19 422 1.0E-30 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS05610 d8127bbb5d2e7339fc1cb8c8d25ee900 427 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 2 422 50.333 T 22-04-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62|UniPathway: UPA00078 TOLA_RS09655 5d9eb9491347ad3c96e554dd848ad6f9 295 SUPERFAMILY SSF53067 1 294 1.77E-53 T 22-04-2016 TOLA_RS09655 5d9eb9491347ad3c96e554dd848ad6f9 295 PANTHER PTHR18964 4 294 1.6E-59 T 22-04-2016 TOLA_RS09655 5d9eb9491347ad3c96e554dd848ad6f9 295 Gene3D G3DSA:3.30.420.40 2 139 1.0E-36 T 22-04-2016 TOLA_RS09655 5d9eb9491347ad3c96e554dd848ad6f9 295 Pfam PF00480 ROK family 4 294 9.4E-55 T 22-04-2016 IPR000600 ROK family TOLA_RS09655 5d9eb9491347ad3c96e554dd848ad6f9 295 PANTHER PTHR18964:SF123 4 294 1.6E-59 T 22-04-2016 TOLA_RS09655 5d9eb9491347ad3c96e554dd848ad6f9 295 Gene3D G3DSA:3.30.420.40 140 272 1.8E-31 T 22-04-2016 TOLA_RS15045 31ce095aad130d181158846d5a6c69f5 324 PANTHER PTHR38418:SF1 10 318 3.8E-39 T 22-04-2016 TOLA_RS15045 31ce095aad130d181158846d5a6c69f5 324 PANTHER PTHR38418 10 318 3.8E-39 T 22-04-2016 TOLA_RS15045 31ce095aad130d181158846d5a6c69f5 324 Gene3D G3DSA:3.40.50.10490 12 191 1.3E-54 T 22-04-2016 TOLA_RS15045 31ce095aad130d181158846d5a6c69f5 324 Gene3D G3DSA:3.10.580.10 192 321 4.5E-38 T 22-04-2016 TOLA_RS15045 31ce095aad130d181158846d5a6c69f5 324 PIRSF PIRSF004692 1 324 1.1E-132 T 22-04-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 TOLA_RS15045 31ce095aad130d181158846d5a6c69f5 324 SMART SM00116 210 258 0.36 T 22-04-2016 IPR000644 CBS domain TOLA_RS15045 31ce095aad130d181158846d5a6c69f5 324 SMART SM00116 275 323 0.015 T 22-04-2016 IPR000644 CBS domain TOLA_RS15045 31ce095aad130d181158846d5a6c69f5 324 Pfam PF00571 CBS domain 269 321 3.4E-7 T 22-04-2016 IPR000644 CBS domain TOLA_RS15045 31ce095aad130d181158846d5a6c69f5 324 Pfam PF00571 CBS domain 204 257 4.5E-5 T 22-04-2016 IPR000644 CBS domain TOLA_RS15045 31ce095aad130d181158846d5a6c69f5 324 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 45 313 2.4E-112 T 22-04-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 TOLA_RS15045 31ce095aad130d181158846d5a6c69f5 324 Pfam PF01380 SIS domain 41 171 2.1E-33 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 TOLA_RS15045 31ce095aad130d181158846d5a6c69f5 324 SUPERFAMILY SSF53697 8 319 6.9E-70 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 SUPERFAMILY SSF53067 8 221 5.65E-63 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 SMART SM00842 10 196 3.9E-100 T 22-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 Gene3D G3DSA:3.30.420.40 157 209 1.2E-24 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 Gene3D G3DSA:3.30.420.40 4 83 1.2E-24 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 Gene3D G3DSA:3.30.420.40 210 234 3.4E-29 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 Gene3D G3DSA:3.30.420.40 298 359 3.4E-29 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 SUPERFAMILY SSF53067 198 384 6.76E-46 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 PIRSF PIRSF003101 1 418 1.2E-153 T 22-04-2016 IPR020823 Cell division protein FtsA GO:0007049 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 Gene3D G3DSA:3.30.1490.110 87 156 8.1E-16 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 2.6E-31 T 22-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 PANTHER PTHR32432:SF4 1 386 4.7E-168 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 385 1.0E-158 T 22-04-2016 IPR020823 Cell division protein FtsA GO:0007049 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 Pfam PF14450 Cell division protein FtsA 207 381 8.0E-25 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 Pfam PF14450 Cell division protein FtsA 11 187 1.9E-9 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 Gene3D G3DSA:3.90.640.10 235 297 6.5E-17 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 PANTHER PTHR32432 1 386 4.7E-168 T 22-04-2016 TOLA_RS02735 d5cccb7b78448ba0afefb9962de0ef68 418 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 418 29.714 T 22-04-2016 IPR020823 Cell division protein FtsA GO:0007049 TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 Gene3D G3DSA:1.20.150.20 383 510 1.3E-48 T 22-04-2016 TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 4.9E-74 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 22-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 SUPERFAMILY SSF50615 10 94 3.53E-26 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.438 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 SUPERFAMILY SSF52540 96 381 2.3E-96 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 2 512 1.3E-256 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 PANTHER PTHR15184:SF3 1 496 1.7E-292 T 22-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 1.4E-45 T 22-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 PANTHER PTHR15184 1 496 1.7E-292 T 22-04-2016 TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 Gene3D G3DSA:3.40.50.300 94 382 6.8E-114 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 92 3.4E-13 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 Gene3D G3DSA:2.40.30.20 1 93 1.6E-29 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16085 2c8a46bbfb26fe6d8ce0e267d28973d1 513 SUPERFAMILY SSF47917 383 511 3.66E-46 T 22-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS05495 ad9dfbe37dd686b166f7039e7eedb453 170 PIRSF PIRSF004982 1 170 4.9E-42 T 22-04-2016 IPR004658 Outer membrane lipoprotein Slp GO:0019867 TOLA_RS05495 ad9dfbe37dd686b166f7039e7eedb453 170 PANTHER PTHR37530 1 150 6.9E-30 T 22-04-2016 TOLA_RS05495 ad9dfbe37dd686b166f7039e7eedb453 170 Pfam PF03843 Outer membrane lipoprotein Slp family 12 159 1.6E-34 T 22-04-2016 IPR004658 Outer membrane lipoprotein Slp GO:0019867 TOLA_RS01765 a7a0a43b019756d79fa93f5e8eb7b911 219 Pfam PF02592 Putative vitamin uptake transporter 42 197 8.3E-35 T 22-04-2016 IPR003744 Protein of unknown function DUF165 TOLA_RS01765 a7a0a43b019756d79fa93f5e8eb7b911 219 PANTHER PTHR34300:SF1 1 215 3.9E-117 T 22-04-2016 TOLA_RS01765 a7a0a43b019756d79fa93f5e8eb7b911 219 PANTHER PTHR34300 1 215 3.9E-117 T 22-04-2016 TOLA_RS01765 a7a0a43b019756d79fa93f5e8eb7b911 219 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 13 201 7.3E-55 T 22-04-2016 IPR003744 Protein of unknown function DUF165 TOLA_RS13280 1fbd270ba9c33dc66af1cb032a6fd526 227 Gene3D G3DSA:1.10.150.240 25 79 9.6E-18 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 TOLA_RS13280 1fbd270ba9c33dc66af1cb032a6fd526 227 Gene3D G3DSA:3.40.50.1000 3 24 1.3E-46 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13280 1fbd270ba9c33dc66af1cb032a6fd526 227 Gene3D G3DSA:3.40.50.1000 80 224 1.3E-46 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13280 1fbd270ba9c33dc66af1cb032a6fd526 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 64 194 1.9E-11 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS13280 1fbd270ba9c33dc66af1cb032a6fd526 227 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 70 193 7.1E-15 T 22-04-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA TOLA_RS13280 1fbd270ba9c33dc66af1cb032a6fd526 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 109 189 1.5E-13 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS13280 1fbd270ba9c33dc66af1cb032a6fd526 227 SUPERFAMILY SSF56784 4 224 7.6E-62 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13280 1fbd270ba9c33dc66af1cb032a6fd526 227 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 10 224 2.2E-65 T 22-04-2016 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181|UniPathway: UPA00865 TOLA_RS13280 1fbd270ba9c33dc66af1cb032a6fd526 227 PANTHER PTHR18901:SF14 1 224 1.7E-66 T 22-04-2016 TOLA_RS13280 1fbd270ba9c33dc66af1cb032a6fd526 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 194 1.6E-38 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13280 1fbd270ba9c33dc66af1cb032a6fd526 227 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 7 225 33.744 T 22-04-2016 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181|UniPathway: UPA00865 TOLA_RS13280 1fbd270ba9c33dc66af1cb032a6fd526 227 PANTHER PTHR18901 1 224 1.7E-66 T 22-04-2016 TOLA_RS07995 e62f51f903ba44bbb47db557cd73ac9c 261 SUPERFAMILY SSF55120 1 252 8.34E-91 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS07995 e62f51f903ba44bbb47db557cd73ac9c 261 Pfam PF01416 tRNA pseudouridine synthase 144 244 3.2E-28 T 22-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS07995 e62f51f903ba44bbb47db557cd73ac9c 261 Pfam PF01416 tRNA pseudouridine synthase 8 102 1.9E-9 T 22-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS07995 e62f51f903ba44bbb47db557cd73ac9c 261 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 243 34.269 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS07995 e62f51f903ba44bbb47db557cd73ac9c 261 PANTHER PTHR11142 1 259 1.1E-98 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS07995 e62f51f903ba44bbb47db557cd73ac9c 261 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 238 9.3E-76 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS07995 e62f51f903ba44bbb47db557cd73ac9c 261 Gene3D G3DSA:3.30.70.580 1 104 2.6E-38 T 22-04-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS07995 e62f51f903ba44bbb47db557cd73ac9c 261 Gene3D G3DSA:3.30.70.660 106 241 3.4E-44 T 22-04-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS07995 e62f51f903ba44bbb47db557cd73ac9c 261 PIRSF PIRSF001430 1 249 4.7E-74 T 22-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS15215 8d2f31d4f9cc61362c87d33e0d89ce67 249 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 235 5.5E-105 T 22-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TOLA_RS15215 8d2f31d4f9cc61362c87d33e0d89ce67 249 Gene3D G3DSA:3.40.1280.10 1 160 6.1E-67 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TOLA_RS15215 8d2f31d4f9cc61362c87d33e0d89ce67 249 PANTHER PTHR32125 1 228 9.3E-119 T 22-04-2016 TOLA_RS15215 8d2f31d4f9cc61362c87d33e0d89ce67 249 PIRSF PIRSF000386 1 249 4.1E-101 T 22-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TOLA_RS15215 8d2f31d4f9cc61362c87d33e0d89ce67 249 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 9.1E-65 T 22-04-2016 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TOLA_RS15215 8d2f31d4f9cc61362c87d33e0d89ce67 249 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 249 116.7 T 22-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TOLA_RS15215 8d2f31d4f9cc61362c87d33e0d89ce67 249 PANTHER PTHR32125:SF1 1 228 9.3E-119 T 22-04-2016 TOLA_RS15215 8d2f31d4f9cc61362c87d33e0d89ce67 249 SUPERFAMILY SSF75217 1 246 1.96E-102 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases TOLA_RS15215 8d2f31d4f9cc61362c87d33e0d89ce67 249 Gene3D G3DSA:1.10.1270.20 162 245 5.2E-35 T 22-04-2016 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TOLA_RS10690 1650f2f784bdbaa640a2fda46d0c1bfd 172 Gene3D G3DSA:3.30.910.20 19 64 6.5E-30 T 22-04-2016 TOLA_RS10690 1650f2f784bdbaa640a2fda46d0c1bfd 172 Gene3D G3DSA:3.30.910.20 102 168 6.5E-30 T 22-04-2016 TOLA_RS10690 1650f2f784bdbaa640a2fda46d0c1bfd 172 Pfam PF03938 Outer membrane protein (OmpH-like) 13 167 2.3E-31 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 TOLA_RS10690 1650f2f784bdbaa640a2fda46d0c1bfd 172 PANTHER PTHR35089:SF1 2 172 1.5E-39 T 22-04-2016 TOLA_RS10690 1650f2f784bdbaa640a2fda46d0c1bfd 172 PANTHER PTHR35089 2 172 1.5E-39 T 22-04-2016 TOLA_RS10690 1650f2f784bdbaa640a2fda46d0c1bfd 172 PIRSF PIRSF002094 1 172 6.6E-45 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 TOLA_RS10690 1650f2f784bdbaa640a2fda46d0c1bfd 172 SMART SM00935 15 169 5.1E-46 T 22-04-2016 IPR005632 Chaperone protein Skp GO:0051082 TOLA_RS10690 1650f2f784bdbaa640a2fda46d0c1bfd 172 SUPERFAMILY SSF111384 26 168 6.8E-34 T 22-04-2016 IPR024930 Skp domain TOLA_RS06790 385935be857d5df5f97d31cefd6385cb 351 Gene3D G3DSA:3.40.50.1820 52 350 2.8E-59 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS06790 385935be857d5df5f97d31cefd6385cb 351 PANTHER PTHR17630:SF49 33 192 8.8E-88 T 22-04-2016 TOLA_RS06790 385935be857d5df5f97d31cefd6385cb 351 PANTHER PTHR17630:SF49 212 351 8.8E-88 T 22-04-2016 TOLA_RS06790 385935be857d5df5f97d31cefd6385cb 351 SUPERFAMILY SSF53474 44 193 2.01E-43 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS06790 385935be857d5df5f97d31cefd6385cb 351 SUPERFAMILY SSF53474 240 342 2.01E-43 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS06790 385935be857d5df5f97d31cefd6385cb 351 PANTHER PTHR17630 33 192 8.8E-88 T 22-04-2016 TOLA_RS06790 385935be857d5df5f97d31cefd6385cb 351 PANTHER PTHR17630 212 351 8.8E-88 T 22-04-2016 TOLA_RS06790 385935be857d5df5f97d31cefd6385cb 351 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 59 242 3.4E-10 T 22-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 TOLA_RS13815 5bc43862c31525020a160cfabff0e170 137 PANTHER PTHR31793 1 128 4.7E-47 T 22-04-2016 TOLA_RS13815 5bc43862c31525020a160cfabff0e170 137 PANTHER PTHR31793:SF9 1 128 4.7E-47 T 22-04-2016 TOLA_RS13815 5bc43862c31525020a160cfabff0e170 137 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 6 128 1.9E-48 T 22-04-2016 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 KEGG: 00360+3.1.2.-|KEGG: 00362+3.1.2.-|KEGG: 00592+3.1.2.-|KEGG: 00903+3.1.2.- TOLA_RS13815 5bc43862c31525020a160cfabff0e170 137 SUPERFAMILY SSF54637 3 132 1.35E-39 T 22-04-2016 IPR029069 HotDog domain TOLA_RS13815 5bc43862c31525020a160cfabff0e170 137 Gene3D G3DSA:3.10.129.10 3 133 3.5E-48 T 22-04-2016 IPR029069 HotDog domain TOLA_RS13815 5bc43862c31525020a160cfabff0e170 137 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 125 1.1E-38 T 22-04-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 TOLA_RS13815 5bc43862c31525020a160cfabff0e170 137 Pfam PF03061 Thioesterase superfamily 20 104 4.0E-17 T 22-04-2016 IPR006683 Thioesterase domain TOLA_RS13815 5bc43862c31525020a160cfabff0e170 137 PIRSF PIRSF003230 1 137 1.4E-45 T 22-04-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 TOLA_RS15965 39a9aeaabb4e97358979304774dd6fdd 65 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 2.4E-15 T 22-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain TOLA_RS15965 39a9aeaabb4e97358979304774dd6fdd 65 PANTHER PTHR37424:SF1 2 58 4.6E-12 T 22-04-2016 TOLA_RS15965 39a9aeaabb4e97358979304774dd6fdd 65 PANTHER PTHR37424 2 58 4.6E-12 T 22-04-2016 TOLA_RS08830 cd29f8a78b7122c551139445dbb8605c 358 Gene3D G3DSA:3.90.1150.10 257 357 6.0E-19 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS08830 cd29f8a78b7122c551139445dbb8605c 358 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 214 223 - T 22-04-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 TOLA_RS08830 cd29f8a78b7122c551139445dbb8605c 358 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 15 356 6.0E-109 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 TOLA_RS08830 cd29f8a78b7122c551139445dbb8605c 358 PANTHER PTHR11751:SF398 45 357 3.3E-87 T 22-04-2016 TOLA_RS08830 cd29f8a78b7122c551139445dbb8605c 358 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 12 358 51.429 T 22-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 TOLA_RS08830 cd29f8a78b7122c551139445dbb8605c 358 SUPERFAMILY SSF53383 19 356 2.36E-74 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS08830 cd29f8a78b7122c551139445dbb8605c 358 Gene3D G3DSA:3.40.640.10 53 256 1.1E-70 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS08830 cd29f8a78b7122c551139445dbb8605c 358 PANTHER PTHR11751 45 357 3.3E-87 T 22-04-2016 TOLA_RS08830 cd29f8a78b7122c551139445dbb8605c 358 Pfam PF00155 Aminotransferase class I and II 43 352 3.2E-56 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TOLA_RS06620 d80503c052fac848ed6e25c75da79142 218 PIRSF PIRSF006324 1 217 8.6E-57 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS06620 d80503c052fac848ed6e25c75da79142 218 PANTHER PTHR30086:SF2 2 214 1.5E-69 T 22-04-2016 TOLA_RS06620 d80503c052fac848ed6e25c75da79142 218 PANTHER PTHR30086 2 214 1.5E-69 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS06620 d80503c052fac848ed6e25c75da79142 218 Pfam PF01810 LysE type translocator 17 214 5.1E-38 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS05385 eb6f4a50343c996ddec5866e1092c0a6 505 PANTHER PTHR30029:SF2 4 494 5.6E-229 T 22-04-2016 TOLA_RS05385 eb6f4a50343c996ddec5866e1092c0a6 505 PANTHER PTHR30029 4 494 5.6E-229 T 22-04-2016 TOLA_RS05385 eb6f4a50343c996ddec5866e1092c0a6 505 Pfam PF04293 SpoVR like protein 14 446 7.4E-178 T 22-04-2016 IPR007390 Sporulation stage V, protein R TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 PANTHER PTHR11353 2 545 7.9E-252 T 22-04-2016 TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 1.6E-251 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 SUPERFAMILY SSF52029 185 376 4.54E-80 T 22-04-2016 IPR027409 GroEL-like apical domain TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 Gene3D G3DSA:3.50.7.10 188 368 3.8E-96 T 22-04-2016 IPR027409 GroEL-like apical domain TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 Gene3D G3DSA:1.10.560.10 3 187 7.3E-46 T 22-04-2016 IPR027413 GroEL-like equatorial domain TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 22-04-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 SUPERFAMILY SSF48592 406 521 2.25E-77 T 22-04-2016 TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 SUPERFAMILY SSF48592 7 134 2.25E-77 T 22-04-2016 TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 Hamap MF_00600 60 kDa chaperonin [groL]. 2 544 41.017 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 524 1.6E-93 T 22-04-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 PRINTS PR00298 60kDa chaperonin signature 268 291 2.5E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 PRINTS PR00298 60kDa chaperonin signature 27 53 2.5E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 PRINTS PR00298 60kDa chaperonin signature 350 375 2.5E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 PRINTS PR00298 60kDa chaperonin signature 83 110 2.5E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 PRINTS PR00298 60kDa chaperonin signature 398 419 2.5E-74 T 22-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 Gene3D G3DSA:1.10.560.10 369 518 1.8E-39 T 22-04-2016 IPR027413 GroEL-like equatorial domain TOLA_RS14420 a08a7eb54234fbe694b5edb78e25f243 545 SUPERFAMILY SSF54849 137 204 2.27E-24 T 22-04-2016 TOLA_RS16290 f4506c1ef8b4fd9b9673e0cba4071109 220 SUPERFAMILY SSF48498 87 215 2.67E-18 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TOLA_RS16290 f4506c1ef8b4fd9b9673e0cba4071109 220 Pfam PF09209 Domain of unknown function (DUF1956) 93 211 9.9E-19 T 22-04-2016 IPR015292 Transcription regulator YbiH, C-terminal TOLA_RS16290 f4506c1ef8b4fd9b9673e0cba4071109 220 SUPERFAMILY SSF46689 14 90 3.39E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS16290 f4506c1ef8b4fd9b9673e0cba4071109 220 Gene3D G3DSA:1.10.357.10 61 217 6.7E-31 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 TOLA_RS16290 f4506c1ef8b4fd9b9673e0cba4071109 220 PANTHER PTHR30055 6 180 1.4E-18 T 22-04-2016 TOLA_RS16290 f4506c1ef8b4fd9b9673e0cba4071109 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 1.9E-12 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS16290 f4506c1ef8b4fd9b9673e0cba4071109 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.4E-6 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS16290 f4506c1ef8b4fd9b9673e0cba4071109 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.4E-6 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS16290 f4506c1ef8b4fd9b9673e0cba4071109 220 Gene3D G3DSA:1.10.10.60 14 60 9.6E-20 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS08055 bf930b92bfc5f1b9a14cdd356a57d625 259 SUPERFAMILY SSF53850 25 256 8.54E-64 T 22-04-2016 TOLA_RS08055 bf930b92bfc5f1b9a14cdd356a57d625 259 PANTHER PTHR18966 7 252 5.4E-103 T 22-04-2016 TOLA_RS08055 bf930b92bfc5f1b9a14cdd356a57d625 259 Gene3D G3DSA:3.40.190.10 25 112 2.2E-42 T 22-04-2016 TOLA_RS08055 bf930b92bfc5f1b9a14cdd356a57d625 259 Gene3D G3DSA:3.40.190.10 214 256 2.2E-42 T 22-04-2016 TOLA_RS08055 bf930b92bfc5f1b9a14cdd356a57d625 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 253 3.8E-62 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS08055 bf930b92bfc5f1b9a14cdd356a57d625 259 Gene3D G3DSA:3.40.190.10 115 212 1.4E-29 T 22-04-2016 TOLA_RS08055 bf930b92bfc5f1b9a14cdd356a57d625 259 SMART SM00062 26 255 7.4E-69 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS08055 bf930b92bfc5f1b9a14cdd356a57d625 259 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 49 62 - T 22-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 TOLA_RS08055 bf930b92bfc5f1b9a14cdd356a57d625 259 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 12 252 2.7E-87 T 22-04-2016 IPR005768 Lysine-arginine-ornithine-binding periplasmic protein GO:0005215|GO:0006810|GO:0030288 TOLA_RS08055 bf930b92bfc5f1b9a14cdd356a57d625 259 PANTHER PTHR18966:SF237 7 252 5.4E-103 T 22-04-2016 TOLA_RS05050 e35f72bc037ed9d414636e09d94c9d8a 168 Gene3D G3DSA:3.10.20.10 1 64 5.4E-25 T 22-04-2016 TOLA_RS05050 e35f72bc037ed9d414636e09d94c9d8a 168 Gene3D G3DSA:3.50.100.10 65 154 4.8E-31 T 22-04-2016 TOLA_RS05050 e35f72bc037ed9d414636e09d94c9d8a 168 Pfam PF07566 Domain of Unknown Function (DUF1543) 15 65 4.9E-18 T 22-04-2016 IPR011440 Domain of unknown function DUF1543 TOLA_RS05050 e35f72bc037ed9d414636e09d94c9d8a 168 Pfam PF07566 Domain of Unknown Function (DUF1543) 91 135 6.8E-12 T 22-04-2016 IPR011440 Domain of unknown function DUF1543 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 Pfam PF02065 Melibiase 254 592 7.0E-120 T 22-04-2016 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 PIRSF PIRSF005536 1 705 1.1E-242 T 22-04-2016 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 Gene3D G3DSA:3.20.20.70 290 574 5.3E-45 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 PRINTS PR00743 Glycosyl hydrolase family 36 signature 478 494 1.9E-59 T 22-04-2016 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 PRINTS PR00743 Glycosyl hydrolase family 36 signature 294 308 1.9E-59 T 22-04-2016 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 PRINTS PR00743 Glycosyl hydrolase family 36 signature 257 277 1.9E-59 T 22-04-2016 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 PRINTS PR00743 Glycosyl hydrolase family 36 signature 322 337 1.9E-59 T 22-04-2016 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 PRINTS PR00743 Glycosyl hydrolase family 36 signature 372 394 1.9E-59 T 22-04-2016 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 PRINTS PR00743 Glycosyl hydrolase family 36 signature 430 445 1.9E-59 T 22-04-2016 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 PRINTS PR00743 Glycosyl hydrolase family 36 signature 503 519 1.9E-59 T 22-04-2016 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 PRINTS PR00743 Glycosyl hydrolase family 36 signature 206 221 1.9E-59 T 22-04-2016 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 610 691 5.0E-8 T 22-04-2016 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 PANTHER PTHR22762:SF81 295 524 2.0E-67 T 22-04-2016 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 23 238 6.1E-47 T 22-04-2016 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 SUPERFAMILY SSF51445 290 620 7.51E-108 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 ProSitePatterns PS00512 Alpha-galactosidase signature. 323 338 - T 22-04-2016 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TOLA_RS10760 e178cd23204718d8fea67f233edccd58 705 PANTHER PTHR22762 295 524 2.0E-67 T 22-04-2016 TOLA_RS09280 de7d679119a1e07ed91f482a81d374b1 363 PANTHER PTHR21327 1 361 7.3E-144 T 22-04-2016 TOLA_RS09280 de7d679119a1e07ed91f482a81d374b1 363 PANTHER PTHR21327:SF6 1 361 7.3E-144 T 22-04-2016 TOLA_RS09280 de7d679119a1e07ed91f482a81d374b1 363 Pfam PF00925 GTP cyclohydrolase II 208 361 4.3E-36 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 TOLA_RS09280 de7d679119a1e07ed91f482a81d374b1 363 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 6 199 4.5E-72 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS09280 de7d679119a1e07ed91f482a81d374b1 363 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 198 1.3E-81 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS09280 de7d679119a1e07ed91f482a81d374b1 363 Gene3D G3DSA:3.90.870.10 2 211 4.7E-96 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TOLA_RS09280 de7d679119a1e07ed91f482a81d374b1 363 PIRSF PIRSF001259 1 363 2.0E-123 T 22-04-2016 TOLA_RS09280 de7d679119a1e07ed91f482a81d374b1 363 SUPERFAMILY SSF142695 205 361 4.05E-44 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 TOLA_RS09280 de7d679119a1e07ed91f482a81d374b1 363 SUPERFAMILY SSF55821 3 202 7.78E-85 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TOLA_RS09280 de7d679119a1e07ed91f482a81d374b1 363 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 37.716 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS11515 4f2b173bcddc3fedd781a4fb8dd4a735 100 Pfam PF01909 Nucleotidyltransferase domain 16 64 5.1E-10 T 22-04-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TOLA_RS11515 4f2b173bcddc3fedd781a4fb8dd4a735 100 Gene3D G3DSA:3.30.460.10 12 96 7.6E-21 T 22-04-2016 TOLA_RS11515 4f2b173bcddc3fedd781a4fb8dd4a735 100 SUPERFAMILY SSF81301 8 92 1.92E-16 T 22-04-2016 TOLA_RS01430 47d610410ed036487a3d83737fba52c0 259 Gene3D G3DSA:3.40.50.720 2 256 7.9E-54 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01430 47d610410ed036487a3d83737fba52c0 259 PANTHER PTHR10953:SF159 194 259 8.6E-127 T 22-04-2016 TOLA_RS01430 47d610410ed036487a3d83737fba52c0 259 PANTHER PTHR10953:SF159 7 161 8.6E-127 T 22-04-2016 TOLA_RS01430 47d610410ed036487a3d83737fba52c0 259 PANTHER PTHR10953 194 259 8.6E-127 T 22-04-2016 TOLA_RS01430 47d610410ed036487a3d83737fba52c0 259 PANTHER PTHR10953 7 161 8.6E-127 T 22-04-2016 TOLA_RS01430 47d610410ed036487a3d83737fba52c0 259 Pfam PF00899 ThiF family 16 254 1.9E-38 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TOLA_RS01430 47d610410ed036487a3d83737fba52c0 259 SUPERFAMILY SSF69572 4 258 1.96E-64 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TOLA_RS04190 d8489e4049ad7ab513cf6580060d6bcf 312 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 311 7.2E-127 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 TOLA_RS04190 d8489e4049ad7ab513cf6580060d6bcf 312 PANTHER PTHR10210:SF41 1 312 1.9E-187 T 22-04-2016 TOLA_RS04190 d8489e4049ad7ab513cf6580060d6bcf 312 SMART SM01400 1 118 2.4E-77 T 22-04-2016 TOLA_RS04190 d8489e4049ad7ab513cf6580060d6bcf 312 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 118 1.9E-50 T 22-04-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 TOLA_RS04190 d8489e4049ad7ab513cf6580060d6bcf 312 Gene3D G3DSA:3.40.50.2020 157 283 2.3E-52 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS04190 d8489e4049ad7ab513cf6580060d6bcf 312 PANTHER PTHR10210 1 312 1.9E-187 T 22-04-2016 TOLA_RS04190 d8489e4049ad7ab513cf6580060d6bcf 312 Gene3D G3DSA:3.40.50.2020 1 156 1.0E-72 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS04190 d8489e4049ad7ab513cf6580060d6bcf 312 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 1 311 49.784 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 TOLA_RS04190 d8489e4049ad7ab513cf6580060d6bcf 312 Pfam PF14572 Phosphoribosyl synthetase-associated domain 201 310 1.0E-28 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 TOLA_RS04190 d8489e4049ad7ab513cf6580060d6bcf 312 SUPERFAMILY SSF53271 66 303 1.86E-67 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS04190 d8489e4049ad7ab513cf6580060d6bcf 312 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 126 141 - T 22-04-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 TOLA_RS11385 468f1240f14b9e9348ca4d6e8f331fe5 89 SUPERFAMILY SSF47060 3 89 4.71E-34 T 22-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 TOLA_RS11385 468f1240f14b9e9348ca4d6e8f331fe5 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 5.2E-38 T 22-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 TOLA_RS11385 468f1240f14b9e9348ca4d6e8f331fe5 89 Gene3D G3DSA:1.10.287.10 3 89 8.6E-38 T 22-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 TOLA_RS11385 468f1240f14b9e9348ca4d6e8f331fe5 89 SMART SM01387 8 88 3.5E-49 T 22-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS11385 468f1240f14b9e9348ca4d6e8f331fe5 89 PANTHER PTHR23321 1 89 2.2E-43 T 22-04-2016 TOLA_RS11385 468f1240f14b9e9348ca4d6e8f331fe5 89 Pfam PF00312 Ribosomal protein S15 8 88 3.7E-36 T 22-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS11385 468f1240f14b9e9348ca4d6e8f331fe5 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.65 T 22-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 TOLA_RS11385 468f1240f14b9e9348ca4d6e8f331fe5 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 4.0E-33 T 22-04-2016 TOLA_RS05580 527f09244a5fa2d69d14a790eb31f537 394 Pfam PF02222 ATP-grasp domain 123 295 7.7E-56 T 22-04-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UniPathway: UPA00074 TOLA_RS05580 527f09244a5fa2d69d14a790eb31f537 394 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 8 393 52.123 T 22-04-2016 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 UniPathway: UPA00074 TOLA_RS05580 527f09244a5fa2d69d14a790eb31f537 394 Gene3D G3DSA:3.30.1490.20 124 198 5.6E-27 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS05580 527f09244a5fa2d69d14a790eb31f537 394 PANTHER PTHR11609 1 392 5.9E-218 T 22-04-2016 TOLA_RS05580 527f09244a5fa2d69d14a790eb31f537 394 Gene3D G3DSA:3.30.470.20 199 389 4.7E-70 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS05580 527f09244a5fa2d69d14a790eb31f537 394 SUPERFAMILY SSF52440 4 112 2.73E-33 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS05580 527f09244a5fa2d69d14a790eb31f537 394 SUPERFAMILY SSF51246 319 392 2.2E-17 T 22-04-2016 IPR011054 Rudiment single hybrid motif TOLA_RS05580 527f09244a5fa2d69d14a790eb31f537 394 SUPERFAMILY SSF56059 113 315 3.18E-58 T 22-04-2016 TOLA_RS05580 527f09244a5fa2d69d14a790eb31f537 394 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 14 393 4.5E-189 T 22-04-2016 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 UniPathway: UPA00074 TOLA_RS05580 527f09244a5fa2d69d14a790eb31f537 394 PANTHER PTHR11609:SF7 1 392 5.9E-218 T 22-04-2016 TOLA_RS05580 527f09244a5fa2d69d14a790eb31f537 394 Gene3D G3DSA:3.40.50.20 6 120 1.8E-39 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 1.3E-42 T 22-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 Gene3D G3DSA:3.10.50.40 156 217 1.6E-8 T 22-04-2016 TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 SUPERFAMILY SSF54534 89 242 2.36E-34 T 22-04-2016 TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 Gene3D G3DSA:3.30.70.1050 1 117 3.8E-39 T 22-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 PANTHER PTHR30560:SF3 1 431 2.3E-130 T 22-04-2016 TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 Gene3D G3DSA:1.10.3120.10 218 389 1.1E-59 T 22-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 Hamap MF_00303 Trigger factor [tig]. 1 419 21.479 T 22-04-2016 IPR005215 Trigger factor GO:0015031 TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 PIRSF PIRSF003095 1 434 2.5E-126 T 22-04-2016 IPR005215 Trigger factor GO:0015031 TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 PANTHER PTHR30560 1 431 2.3E-130 T 22-04-2016 TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 SUPERFAMILY SSF102735 1 129 2.22E-39 T 22-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 TIGRFAM TIGR00115 tig: trigger factor 11 413 8.8E-141 T 22-04-2016 IPR005215 Trigger factor GO:0015031 TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 SUPERFAMILY SSF109998 248 430 9.16E-46 T 22-04-2016 IPR027304 Trigger factor/SurA domain TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 156 237 2.2E-12 T 22-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 TOLA_RS05540 a4e2ed8f814974686e273ebf25a710f0 436 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 262 413 4.2E-34 T 22-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 TOLA_RS06510 9c26808d3f44fd1845e11a1f88b06e82 633 Pfam PF00884 Sulfatase 276 543 8.6E-42 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 TOLA_RS06510 9c26808d3f44fd1845e11a1f88b06e82 633 Gene3D G3DSA:3.40.720.10 276 557 1.1E-43 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 TOLA_RS06510 9c26808d3f44fd1845e11a1f88b06e82 633 PIRSF PIRSF005091 8 585 2.5E-77 T 22-04-2016 IPR012160 Lipoteichoic acid synthase-like KEGG: 00440+2.7.8.-|KEGG: 00513+2.7.8.-|KEGG: 00540+2.7.8.-|KEGG: 00564+2.7.8.-|KEGG: 00600+2.7.8.-|KEGG: 00770+2.7.8.-|UniPathway: UPA00556 TOLA_RS06510 9c26808d3f44fd1845e11a1f88b06e82 633 PANTHER PTHR10342 247 600 2.0E-63 T 22-04-2016 TOLA_RS06510 9c26808d3f44fd1845e11a1f88b06e82 633 PANTHER PTHR10342:SF236 247 600 2.0E-63 T 22-04-2016 TOLA_RS06510 9c26808d3f44fd1845e11a1f88b06e82 633 SUPERFAMILY SSF53649 274 588 4.94E-64 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 TOLA_RS09060 f58c37ab9e477a9fe451d53568191b1f 296 SUPERFAMILY SSF89550 2 83 7.26E-36 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 TOLA_RS09060 f58c37ab9e477a9fe451d53568191b1f 296 SUPERFAMILY SSF89550 182 272 7.26E-36 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 TOLA_RS09060 f58c37ab9e477a9fe451d53568191b1f 296 SMART SM00481 4 70 4.7E-11 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 TOLA_RS09060 f58c37ab9e477a9fe451d53568191b1f 296 Gene3D G3DSA:3.20.20.140 1 88 4.8E-33 T 22-04-2016 TOLA_RS09060 f58c37ab9e477a9fe451d53568191b1f 296 Gene3D G3DSA:3.20.20.140 174 277 4.8E-33 T 22-04-2016 TOLA_RS09060 f58c37ab9e477a9fe451d53568191b1f 296 Pfam PF02811 PHP domain 5 134 3.5E-9 T 22-04-2016 IPR004013 PHP domain GO:0003824 TOLA_RS09060 f58c37ab9e477a9fe451d53568191b1f 296 PANTHER PTHR30007 1 269 1.2E-18 T 22-04-2016 TOLA_RS09060 f58c37ab9e477a9fe451d53568191b1f 296 PANTHER PTHR30007:SF4 1 269 1.2E-18 T 22-04-2016 TOLA_RS02300 fa32cda32129756874e2b0daa2482803 457 SMART SM00729 52 272 2.3E-55 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TOLA_RS02300 fa32cda32129756874e2b0daa2482803 457 Pfam PF04055 Radical SAM superfamily 57 228 2.8E-20 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS02300 fa32cda32129756874e2b0daa2482803 457 PANTHER PTHR13932:SF6 1 451 3.4E-250 T 22-04-2016 TOLA_RS02300 fa32cda32129756874e2b0daa2482803 457 PANTHER PTHR13932 1 451 3.4E-250 T 22-04-2016 TOLA_RS02300 fa32cda32129756874e2b0daa2482803 457 PIRSF PIRSF000167 3 454 2.5E-172 T 22-04-2016 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22|UniPathway: UPA00251 TOLA_RS02300 fa32cda32129756874e2b0daa2482803 457 SUPERFAMILY SSF102114 5 444 2.09E-148 T 22-04-2016 TOLA_RS02300 fa32cda32129756874e2b0daa2482803 457 Pfam PF06969 HemN C-terminal domain 363 431 3.8E-10 T 22-04-2016 IPR010723 HemN, C-terminal TOLA_RS02300 fa32cda32129756874e2b0daa2482803 457 Gene3D G3DSA:3.80.30.20 53 281 4.1E-34 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe TOLA_RS02300 fa32cda32129756874e2b0daa2482803 457 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 8 457 7.7E-207 T 22-04-2016 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22|UniPathway: UPA00251 TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 Gene3D G3DSA:3.30.70.270 494 662 1.7E-35 T 22-04-2016 TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 PANTHER PTHR33121:SF16 662 924 1.4E-64 T 22-04-2016 TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 Gene3D G3DSA:3.20.20.450 668 921 3.2E-89 T 22-04-2016 IPR001633 EAL domain TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 492 653 5.0E-26 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 Pfam PF00990 Diguanylate cyclase, GGDEF domain 494 648 1.3E-28 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 Pfam PF05228 CHASE4 domain 59 220 4.2E-23 T 22-04-2016 IPR007892 CHASE4 TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 SUPERFAMILY SSF141868 670 921 8.5E-83 T 22-04-2016 IPR001633 EAL domain TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 SUPERFAMILY SSF55073 497 655 1.8E-31 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 365 487 2.9E-11 T 22-04-2016 IPR000014 PAS domain TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 SMART SM00086 441 481 0.008 T 22-04-2016 IPR001610 PAC motif TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 Pfam PF00563 EAL domain 670 909 3.5E-68 T 22-04-2016 IPR001633 EAL domain TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 Pfam PF13426 PAS domain 382 480 2.1E-12 T 22-04-2016 IPR000014 PAS domain TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 SMART SM00267 481 654 3.4E-27 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 Gene3D G3DSA:3.30.450.20 360 478 1.8E-13 T 22-04-2016 TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 SUPERFAMILY SSF55785 358 479 8.2E-14 T 22-04-2016 IPR000014 PAS domain TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 SMART SM00052 664 914 2.3E-95 T 22-04-2016 IPR001633 EAL domain TOLA_RS14550 f83e28434ed6c09a51d615b229b0ec5c 930 PANTHER PTHR33121 662 924 1.4E-64 T 22-04-2016 TOLA_RS08915 900c6b04f41e03fb8d4d301070bc3db9 277 PANTHER PTHR17630 51 273 1.2E-42 T 22-04-2016 TOLA_RS08915 900c6b04f41e03fb8d4d301070bc3db9 277 SUPERFAMILY SSF53474 43 272 7.38E-42 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS08915 900c6b04f41e03fb8d4d301070bc3db9 277 PANTHER PTHR17630:SF42 51 273 1.2E-42 T 22-04-2016 TOLA_RS08915 900c6b04f41e03fb8d4d301070bc3db9 277 Pfam PF01738 Dienelactone hydrolase family 57 271 3.2E-48 T 22-04-2016 IPR002925 Dienelactone hydrolase GO:0016787 TOLA_RS08915 900c6b04f41e03fb8d4d301070bc3db9 277 Gene3D G3DSA:3.40.50.1820 43 270 3.5E-49 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS00530 60d2a8904513fd0b89dd453409b0deae 101 Pfam PF00276 Ribosomal protein L23 9 95 1.2E-32 T 22-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00530 60d2a8904513fd0b89dd453409b0deae 101 PANTHER PTHR11620 9 95 4.4E-32 T 22-04-2016 TOLA_RS00530 60d2a8904513fd0b89dd453409b0deae 101 Gene3D G3DSA:3.30.70.330 6 98 1.7E-36 T 22-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 TOLA_RS00530 60d2a8904513fd0b89dd453409b0deae 101 SUPERFAMILY SSF54189 6 98 2.81E-33 T 22-04-2016 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00530 60d2a8904513fd0b89dd453409b0deae 101 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 8 98 23.523 T 22-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TOLA_RS05615 66e78df3fe20d0eeb071d851e24803f1 355 SMART SM00729 45 257 2.3E-45 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TOLA_RS05615 66e78df3fe20d0eeb071d851e24803f1 355 Gene3D G3DSA:3.20.20.70 7 315 6.8E-107 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS05615 66e78df3fe20d0eeb071d851e24803f1 355 PANTHER PTHR22976:SF1 6 348 1.8E-181 T 22-04-2016 TOLA_RS05615 66e78df3fe20d0eeb071d851e24803f1 355 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 222 313 3.0E-21 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 TOLA_RS05615 66e78df3fe20d0eeb071d851e24803f1 355 SMART SM00876 222 314 1.8E-49 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 TOLA_RS05615 66e78df3fe20d0eeb071d851e24803f1 355 TIGRFAM TIGR00433 bioB: biotin synthase 17 313 6.9E-128 T 22-04-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 TOLA_RS05615 66e78df3fe20d0eeb071d851e24803f1 355 Hamap MF_01694 Biotin synthase [bioB]. 7 315 42.677 T 22-04-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 TOLA_RS05615 66e78df3fe20d0eeb071d851e24803f1 355 Pfam PF04055 Radical SAM superfamily 52 203 9.1E-17 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS05615 66e78df3fe20d0eeb071d851e24803f1 355 PANTHER PTHR22976 6 348 1.8E-181 T 22-04-2016 TOLA_RS05615 66e78df3fe20d0eeb071d851e24803f1 355 SUPERFAMILY SSF102114 7 315 7.59E-96 T 22-04-2016 TOLA_RS05615 66e78df3fe20d0eeb071d851e24803f1 355 PIRSF PIRSF001619 1 320 2.4E-138 T 22-04-2016 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 TOLA_RS02265 01fea03f7e640acf6f8db2eb1ee28428 439 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 88 435 9.0E-97 T 22-04-2016 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 TOLA_RS02265 01fea03f7e640acf6f8db2eb1ee28428 439 Pfam PF00425 chorismate binding enzyme 178 429 3.2E-61 T 22-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal TOLA_RS02265 01fea03f7e640acf6f8db2eb1ee28428 439 PANTHER PTHR11236 21 434 3.0E-106 T 22-04-2016 TOLA_RS02265 01fea03f7e640acf6f8db2eb1ee28428 439 SUPERFAMILY SSF56322 19 436 1.02E-90 T 22-04-2016 IPR005801 ADC synthase GO:0009058 TOLA_RS02265 01fea03f7e640acf6f8db2eb1ee28428 439 Gene3D G3DSA:3.60.120.10 32 436 1.4E-82 T 22-04-2016 IPR005801 ADC synthase GO:0009058 TOLA_RS02265 01fea03f7e640acf6f8db2eb1ee28428 439 PANTHER PTHR11236:SF3 21 434 3.0E-106 T 22-04-2016 TOLA_RS02265 01fea03f7e640acf6f8db2eb1ee28428 439 Hamap MF_01935 Isochorismate synthase MenF [menF]. 1 439 37.675 T 22-04-2016 TOLA_RS07955 844d7e7a40fb9fe20cac31e8967a48a7 251 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 5 250 25.448 T 22-04-2016 IPR013033 Septum formation inhibitor MinC GO:0000917|GO:0051726 TOLA_RS07955 844d7e7a40fb9fe20cac31e8967a48a7 251 Gene3D G3DSA:2.160.20.70 137 249 1.0E-37 T 22-04-2016 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 TOLA_RS07955 844d7e7a40fb9fe20cac31e8967a48a7 251 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 1 103 1.2E-21 T 22-04-2016 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 TOLA_RS07955 844d7e7a40fb9fe20cac31e8967a48a7 251 PANTHER PTHR34108 7 245 6.8E-51 T 22-04-2016 TOLA_RS07955 844d7e7a40fb9fe20cac31e8967a48a7 251 PANTHER PTHR34108:SF1 7 245 6.8E-51 T 22-04-2016 TOLA_RS07955 844d7e7a40fb9fe20cac31e8967a48a7 251 SUPERFAMILY SSF63848 145 249 2.88E-31 T 22-04-2016 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 TOLA_RS07955 844d7e7a40fb9fe20cac31e8967a48a7 251 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 7 248 3.1E-54 T 22-04-2016 IPR013033 Septum formation inhibitor MinC GO:0000917|GO:0051726 TOLA_RS07955 844d7e7a40fb9fe20cac31e8967a48a7 251 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 147 246 5.0E-32 T 22-04-2016 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 Gene3D G3DSA:3.20.20.80 6 108 9.4E-120 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 Gene3D G3DSA:3.20.20.80 179 479 9.4E-120 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 PANTHER PTHR10357 456 514 1.0E-214 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 PANTHER PTHR10357 1 424 1.0E-214 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 SUPERFAMILY SSF51445 7 477 6.45E-150 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 Pfam PF00128 Alpha amylase, catalytic domain 32 377 9.3E-114 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 PANTHER PTHR10357:SF142 456 514 1.0E-214 T 22-04-2016 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 PANTHER PTHR10357:SF142 1 424 1.0E-214 T 22-04-2016 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 SMART SM00642 17 419 1.0E-152 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 Gene3D G3DSA:2.60.40.1180 481 557 2.5E-16 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 SUPERFAMILY SSF51011 480 556 1.13E-15 T 22-04-2016 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 Gene3D G3DSA:3.90.400.10 109 178 3.5E-32 T 22-04-2016 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 PRINTS PR00110 Alpha-amylase signature 320 332 9.3E-6 T 22-04-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 PRINTS PR00110 Alpha-amylase signature 197 208 9.3E-6 T 22-04-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 PRINTS PR00110 Alpha-amylase signature 96 107 9.3E-6 T 22-04-2016 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: REACT_474 TOLA_RS06295 9882ff9f449435fc2f1cacfab0222aa8 558 Pfam PF16657 Maltogenic Amylase, C-terminal domain 480 553 1.7E-7 T 22-04-2016 IPR032091 Maltogenic Amylase, C-terminal TOLA_RS08335 f2f6afe999bac544fafa8a80bdb6c832 312 SUPERFAMILY SSF52402 150 309 1.34E-21 T 22-04-2016 TOLA_RS08335 f2f6afe999bac544fafa8a80bdb6c832 312 Gene3D G3DSA:3.40.50.620 137 304 2.7E-24 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS08335 f2f6afe999bac544fafa8a80bdb6c832 312 PANTHER PTHR31964 134 310 1.5E-24 T 22-04-2016 TOLA_RS08335 f2f6afe999bac544fafa8a80bdb6c832 312 PANTHER PTHR31964:SF26 134 310 1.5E-24 T 22-04-2016 TOLA_RS08335 f2f6afe999bac544fafa8a80bdb6c832 312 SUPERFAMILY SSF52402 1 141 1.09E-9 T 22-04-2016 TOLA_RS08335 f2f6afe999bac544fafa8a80bdb6c832 312 Gene3D G3DSA:3.40.50.620 4 136 3.7E-9 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS08335 f2f6afe999bac544fafa8a80bdb6c832 312 Pfam PF00582 Universal stress protein family 150 301 7.6E-15 T 22-04-2016 IPR006016 UspA GO:0006950 TOLA_RS08335 f2f6afe999bac544fafa8a80bdb6c832 312 Pfam PF00582 Universal stress protein family 4 139 7.5E-6 T 22-04-2016 IPR006016 UspA GO:0006950 TOLA_RS03140 395346e62599d5e42e43008ec172ca53 164 Gene3D G3DSA:1.20.144.10 4 163 7.4E-36 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TOLA_RS03140 395346e62599d5e42e43008ec172ca53 164 PANTHER PTHR14969 4 160 1.3E-31 T 22-04-2016 TOLA_RS03140 395346e62599d5e42e43008ec172ca53 164 Pfam PF01569 PAP2 superfamily 63 161 2.0E-17 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TOLA_RS03140 395346e62599d5e42e43008ec172ca53 164 SUPERFAMILY SSF48317 4 163 5.49E-35 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TOLA_RS03140 395346e62599d5e42e43008ec172ca53 164 SMART SM00014 59 163 7.3E-14 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TOLA_RS11230 4972854dff12604f3975ec582843da8a 325 Hamap MF_00323 Ferrochelatase [hemH]. 3 320 36.639 T 22-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 TOLA_RS11230 4972854dff12604f3975ec582843da8a 325 Pfam PF00762 Ferrochelatase 4 318 1.7E-105 T 22-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 TOLA_RS11230 4972854dff12604f3975ec582843da8a 325 Gene3D G3DSA:3.40.50.1400 3 201 6.1E-62 T 22-04-2016 TOLA_RS11230 4972854dff12604f3975ec582843da8a 325 ProSitePatterns PS00534 Ferrochelatase signature. 189 207 - T 22-04-2016 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 TOLA_RS11230 4972854dff12604f3975ec582843da8a 325 PANTHER PTHR11108 3 317 1.8E-116 T 22-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 TOLA_RS11230 4972854dff12604f3975ec582843da8a 325 SUPERFAMILY SSF53800 2 323 5.1E-100 T 22-04-2016 TOLA_RS11230 4972854dff12604f3975ec582843da8a 325 TIGRFAM TIGR00109 hemH: ferrochelatase 3 318 1.0E-96 T 22-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 TOLA_RS11230 4972854dff12604f3975ec582843da8a 325 Gene3D G3DSA:3.40.50.1400 202 320 1.3E-38 T 22-04-2016 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 SUPERFAMILY SSF52009 235 351 6.02E-19 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 Gene3D G3DSA:3.50.30.10 242 365 1.4E-21 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 Pfam PF00381 PTS HPr component phosphorylation site 9 86 1.4E-10 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 686 829 3.4E-34 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 PANTHER PTHR22931:SF24 180 660 7.6E-191 T 22-04-2016 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 557 575 - T 22-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 SUPERFAMILY SSF55804 685 829 5.23E-36 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 119 675 3.2E-132 T 22-04-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 Pfam PF00391 PEP-utilising enzyme, mobile domain 266 336 1.9E-12 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 15 22 - T 22-04-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 732 748 - T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 687 814 3.4E-32 T 22-04-2016 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 PANTHER PTHR22931 180 660 7.6E-191 T 22-04-2016 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 Gene3D G3DSA:3.20.20.60 371 677 3.1E-97 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 Pfam PF05524 PEP-utilising enzyme, N-terminal 119 236 1.1E-16 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 PRINTS PR00107 Phosphocarrier protein signature 42 57 1.2E-5 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 PRINTS PR00107 Phosphocarrier protein signature 15 31 1.2E-5 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 Gene3D G3DSA:1.10.274.10 146 241 1.6E-15 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 SUPERFAMILY SSF47831 146 251 2.35E-14 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 SUPERFAMILY SSF55594 6 91 6.28E-16 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 370 651 3.4E-98 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 SUPERFAMILY SSF51621 371 659 4.71E-96 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 Gene3D G3DSA:3.40.930.10 684 830 1.8E-42 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 Gene3D G3DSA:3.30.1340.10 6 91 7.7E-17 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 610 622 1.0E-21 T 22-04-2016 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 404 423 1.0E-21 T 22-04-2016 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 574 589 1.0E-21 T 22-04-2016 TOLA_RS02320 cc19ace5cc5240637428806192dd0de9 833 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 557 572 1.0E-21 T 22-04-2016 TOLA_RS05010 438641b77ea0698217387b6c7d069539 574 Pfam PF01368 DHH family 72 205 1.0E-11 T 22-04-2016 IPR001667 DDH domain TOLA_RS05010 438641b77ea0698217387b6c7d069539 574 Pfam PF02272 DHHA1 domain 380 448 2.8E-15 T 22-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 TOLA_RS05010 438641b77ea0698217387b6c7d069539 574 PANTHER PTHR30255 2 571 1.4E-211 T 22-04-2016 TOLA_RS05010 438641b77ea0698217387b6c7d069539 574 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 22 570 5.7E-156 T 22-04-2016 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 TOLA_RS05010 438641b77ea0698217387b6c7d069539 574 SUPERFAMILY SSF64182 46 464 9.16E-117 T 22-04-2016 TOLA_RS05010 438641b77ea0698217387b6c7d069539 574 PANTHER PTHR30255:SF2 2 571 1.4E-211 T 22-04-2016 TOLA_RS05010 438641b77ea0698217387b6c7d069539 574 Gene3D G3DSA:3.40.50.2020 49 106 7.3E-4 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS08420 6c9566bad88b9b312327480e54355334 204 Pfam PF01810 LysE type translocator 16 200 1.0E-22 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS08420 6c9566bad88b9b312327480e54355334 204 PANTHER PTHR30086 1 198 1.5E-41 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS08420 6c9566bad88b9b312327480e54355334 204 PANTHER PTHR30086:SF3 1 198 1.5E-41 T 22-04-2016 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 SMART SM01016 3 91 5.6E-38 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 SUPERFAMILY SSF52374 116 458 7.5E-86 T 22-04-2016 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 5 580 1.6E-180 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 Gene3D G3DSA:3.40.50.620 117 458 9.4E-108 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 Pfam PF00750 tRNA synthetases class I (R) 108 451 6.6E-156 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 580 26.851 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 4 91 7.4E-25 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 PANTHER PTHR11956:SF1 1 580 6.5E-245 T 22-04-2016 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 PRINTS PR01038 Arginyl-tRNA synthetase signature 308 329 4.73E-20 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 PRINTS PR01038 Arginyl-tRNA synthetase signature 134 150 4.73E-20 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 PRINTS PR01038 Arginyl-tRNA synthetase signature 119 134 4.73E-20 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 PRINTS PR01038 Arginyl-tRNA synthetase signature 158 171 4.73E-20 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 SMART SM00836 465 580 5.3E-37 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 SUPERFAMILY SSF47323 459 580 5.82E-34 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 Pfam PF05746 DALR anticodon binding domain 465 580 6.3E-30 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 Gene3D G3DSA:3.30.1360.70 3 107 3.0E-33 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 SUPERFAMILY SSF55190 6 102 6.41E-25 T 22-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 PANTHER PTHR11956 1 580 6.5E-245 T 22-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 TOLA_RS02450 4803996a452c40c731a40d94170da5bb 580 Gene3D G3DSA:1.10.730.10 459 580 7.9E-35 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS03270 d1c5501e2b6e9f4c57a03bc67f358e5e 153 PANTHER PTHR21666:SF210 17 150 2.0E-46 T 22-04-2016 TOLA_RS03270 d1c5501e2b6e9f4c57a03bc67f358e5e 153 SUPERFAMILY SSF54001 29 151 1.41E-39 T 22-04-2016 TOLA_RS03270 d1c5501e2b6e9f4c57a03bc67f358e5e 153 Pfam PF00877 NlpC/P60 family 46 150 1.3E-30 T 22-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS03270 d1c5501e2b6e9f4c57a03bc67f358e5e 153 PANTHER PTHR21666 17 150 2.0E-46 T 22-04-2016 TOLA_RS03270 d1c5501e2b6e9f4c57a03bc67f358e5e 153 Gene3D G3DSA:3.90.1720.10 33 152 1.0E-41 T 22-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS09920 7de098a2bddf08a60bd70d2118cae2d6 218 SMART SM01236 73 170 6.5E-6 T 22-04-2016 TOLA_RS09920 7de098a2bddf08a60bd70d2118cae2d6 218 Gene3D G3DSA:1.20.910.10 1 213 2.7E-18 T 22-04-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 TOLA_RS09920 7de098a2bddf08a60bd70d2118cae2d6 218 SUPERFAMILY SSF48613 1 214 1.81E-63 T 22-04-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 TOLA_RS09920 7de098a2bddf08a60bd70d2118cae2d6 218 Pfam PF14518 Iron-containing redox enzyme 39 206 3.1E-26 T 22-04-2016 IPR028201 PqqC-like protein TOLA_RS14130 d9842f7e08edbbed6c0e47f6befa2bc1 377 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS14130 d9842f7e08edbbed6c0e47f6befa2bc1 377 Pfam PF00005 ABC transporter 35 177 3.2E-39 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS14130 d9842f7e08edbbed6c0e47f6befa2bc1 377 SMART SM00382 44 227 3.4E-19 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS14130 d9842f7e08edbbed6c0e47f6befa2bc1 377 PANTHER PTHR24220 21 337 9.2E-187 T 22-04-2016 TOLA_RS14130 d9842f7e08edbbed6c0e47f6befa2bc1 377 PANTHER PTHR24220:SF481 21 337 9.2E-187 T 22-04-2016 TOLA_RS14130 d9842f7e08edbbed6c0e47f6befa2bc1 377 SUPERFAMILY SSF52540 19 259 3.0E-88 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14130 d9842f7e08edbbed6c0e47f6befa2bc1 377 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 50 375 2.5E-137 T 22-04-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 TOLA_RS14130 d9842f7e08edbbed6c0e47f6befa2bc1 377 SUPERFAMILY SSF50331 252 375 7.65E-18 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS14130 d9842f7e08edbbed6c0e47f6befa2bc1 377 Gene3D G3DSA:3.40.50.300 12 253 2.1E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14130 d9842f7e08edbbed6c0e47f6befa2bc1 377 Pfam PF08402 TOBE domain 295 375 6.3E-18 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 Pfam PF01330 RuvA N terminal domain 2 62 2.1E-19 T 22-04-2016 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 SUPERFAMILY SSF47781 65 138 3.89E-22 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 Gene3D G3DSA:2.40.50.140 2 65 1.6E-26 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 PANTHER PTHR33796 2 206 2.2E-78 T 22-04-2016 TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 Pfam PF14520 Helix-hairpin-helix domain 72 130 2.8E-15 T 22-04-2016 TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 SUPERFAMILY SSF46929 161 205 3.79E-11 T 22-04-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 Pfam PF07499 RuvA, C-terminal domain 163 205 7.8E-15 T 22-04-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 206 31.192 T 22-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 Gene3D G3DSA:1.10.150.20 67 141 7.8E-31 T 22-04-2016 TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 206 2.3E-67 T 22-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 SUPERFAMILY SSF50249 2 63 2.8E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 Gene3D G3DSA:1.10.8.10 160 205 1.1E-20 T 22-04-2016 TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 SMART SM00278 73 92 2.7 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TOLA_RS13840 ce909c3838bd43cd9f4d62e49cf91801 206 SMART SM00278 108 127 0.042 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TOLA_RS13405 91eb0cc8e68f3bb00492e8725e6f788b 345 SUPERFAMILY SSF54197 2 175 8.99E-73 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 TOLA_RS13405 91eb0cc8e68f3bb00492e8725e6f788b 345 PIRSF PIRSF000808 1 339 1.9E-124 T 22-04-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13405 91eb0cc8e68f3bb00492e8725e6f788b 345 PANTHER PTHR11943 1 344 1.4E-209 T 22-04-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13405 91eb0cc8e68f3bb00492e8725e6f788b 345 Gene3D G3DSA:3.30.428.10 44 173 5.2E-57 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 TOLA_RS13405 91eb0cc8e68f3bb00492e8725e6f788b 345 Gene3D G3DSA:3.30.428.10 174 343 2.5E-76 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 TOLA_RS13405 91eb0cc8e68f3bb00492e8725e6f788b 345 SUPERFAMILY SSF54197 181 343 2.38E-54 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 TOLA_RS13405 91eb0cc8e68f3bb00492e8725e6f788b 345 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 183 344 1.6E-67 T 22-04-2016 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13405 91eb0cc8e68f3bb00492e8725e6f788b 345 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 3 174 7.3E-69 T 22-04-2016 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13405 91eb0cc8e68f3bb00492e8725e6f788b 345 PANTHER PTHR11943:SF2 1 344 1.4E-209 T 22-04-2016 TOLA_RS13405 91eb0cc8e68f3bb00492e8725e6f788b 345 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 2 344 2.6E-190 T 22-04-2016 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13405 91eb0cc8e68f3bb00492e8725e6f788b 345 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 149 166 - T 22-04-2016 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site GO:0006012|GO:0008108|GO:0008270 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS05925 59fce72bf5ae77ec4989ea442cb957d3 487 Gene3D G3DSA:3.40.50.300 120 193 1.1E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05925 59fce72bf5ae77ec4989ea442cb957d3 487 Gene3D G3DSA:3.40.50.300 293 420 1.1E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05925 59fce72bf5ae77ec4989ea442cb957d3 487 Gene3D G3DSA:3.40.50.300 1 55 1.1E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05925 59fce72bf5ae77ec4989ea442cb957d3 487 Pfam PF13175 AAA ATPase domain 317 416 5.2E-10 T 22-04-2016 TOLA_RS05925 59fce72bf5ae77ec4989ea442cb957d3 487 Pfam PF13175 AAA ATPase domain 1 134 1.5E-9 T 22-04-2016 TOLA_RS05925 59fce72bf5ae77ec4989ea442cb957d3 487 SUPERFAMILY SSF52540 264 420 1.55E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05925 59fce72bf5ae77ec4989ea442cb957d3 487 SUPERFAMILY SSF52540 1 51 1.55E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11955 0f04978b2526eadbec9744b333645036 247 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 50 221 3.8E-49 T 22-04-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 TOLA_RS11955 0f04978b2526eadbec9744b333645036 247 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 35 245 1.9E-87 T 22-04-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 TOLA_RS11955 0f04978b2526eadbec9744b333645036 247 PANTHER PTHR23293:SF5 19 247 7.0E-95 T 22-04-2016 TOLA_RS11955 0f04978b2526eadbec9744b333645036 247 SUPERFAMILY SSF52402 23 210 2.32E-57 T 22-04-2016 TOLA_RS11955 0f04978b2526eadbec9744b333645036 247 PIRSF PIRSF000857 6 247 5.6E-58 T 22-04-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 TOLA_RS11955 0f04978b2526eadbec9744b333645036 247 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 11 245 40.538 T 22-04-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 TOLA_RS11955 0f04978b2526eadbec9744b333645036 247 Gene3D G3DSA:3.40.50.620 13 217 5.0E-65 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS11955 0f04978b2526eadbec9744b333645036 247 PANTHER PTHR23293 19 247 7.0E-95 T 22-04-2016 TOLA_RS11955 0f04978b2526eadbec9744b333645036 247 TIGRFAM TIGR02057 PAPS_reductase: phosphoadenosine phosphosulfate reductase 23 244 5.4E-92 T 22-04-2016 IPR011800 Phosphoadenosine phosphosulphate reductase CysH GO:0004604|GO:0019379 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 Pfam PF00005 ABC transporter 330 483 1.6E-34 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 Pfam PF00005 ABC transporter 24 181 4.5E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 SUPERFAMILY SSF52540 303 553 9.21E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 SUPERFAMILY SSF52540 3 253 7.82E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 ProSitePatterns PS00211 ABC transporters family signature. 455 469 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 PANTHER PTHR24220 5 293 2.7E-192 T 22-04-2016 TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 PANTHER PTHR24220 329 427 2.7E-192 T 22-04-2016 TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 SMART SM00382 338 532 1.4E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 SMART SM00382 32 231 1.4E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 Gene3D G3DSA:3.40.50.300 302 555 2.5E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 Gene3D G3DSA:3.40.50.300 2 255 2.9E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 PANTHER PTHR24220:SF336 5 293 2.7E-192 T 22-04-2016 TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 PANTHER PTHR24220:SF336 329 427 2.7E-192 T 22-04-2016 TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 263 3.1E-6 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TOLA_RS12795 40830798a5cfc15b15eb55265608ad87 583 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 534 577 0.0014 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TOLA_RS14095 7b0d3977441b96fa23203f99fa95f993 161 PANTHER PTHR33254 1 161 7.9E-95 T 22-04-2016 TOLA_RS14095 7b0d3977441b96fa23203f99fa95f993 161 Gene3D G3DSA:3.50.30.40 1 157 5.5E-42 T 22-04-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TOLA_RS14095 7b0d3977441b96fa23203f99fa95f993 161 SUPERFAMILY SSF89562 2 159 4.32E-41 T 22-04-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TOLA_RS14095 7b0d3977441b96fa23203f99fa95f993 161 Pfam PF03737 Demethylmenaquinone methyltransferase 5 152 2.4E-32 T 22-04-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TOLA_RS14095 7b0d3977441b96fa23203f99fa95f993 161 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 154 1.2E-60 T 22-04-2016 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 TOLA_RS14095 7b0d3977441b96fa23203f99fa95f993 161 PANTHER PTHR33254:SF7 1 161 7.9E-95 T 22-04-2016 TOLA_RS14095 7b0d3977441b96fa23203f99fa95f993 161 TIGRFAM TIGR02998 RraA_entero: regulator of ribonuclease activity A 1 161 1.1E-80 T 22-04-2016 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 TOLA_RS14095 7b0d3977441b96fa23203f99fa95f993 161 Hamap MF_00471 Regulator of ribonuclease activity A [rraA]. 1 161 47.757 T 22-04-2016 IPR014339 Regulator of ribonuclease activity A, gammaproteobacteria GO:0008428|GO:0051252 TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 SMART SM00642 98 553 4.8E-26 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 Pfam PF00128 Alpha amylase, catalytic domain 108 306 7.2E-37 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 Pfam PF16657 Maltogenic Amylase, C-terminal domain 564 639 7.5E-7 T 22-04-2016 IPR032091 Maltogenic Amylase, C-terminal TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 PANTHER PTHR10357 46 395 2.4E-158 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 PANTHER PTHR10357 437 619 2.4E-158 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 Gene3D G3DSA:3.90.400.10 185 255 3.5E-23 T 22-04-2016 TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 Gene3D G3DSA:3.20.20.80 93 184 3.4E-89 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 Gene3D G3DSA:3.20.20.80 263 554 3.4E-89 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 PANTHER PTHR10357:SF122 46 395 2.4E-158 T 22-04-2016 TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 PANTHER PTHR10357:SF122 437 619 2.4E-158 T 22-04-2016 TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 SUPERFAMILY SSF51445 19 560 1.34E-107 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 SUPERFAMILY SSF51011 564 641 2.38E-11 T 22-04-2016 TOLA_RS06835 8b9a429b1f5bb95fa69f31c6ae8c1dcd 643 Gene3D G3DSA:2.60.40.1180 565 641 1.1E-18 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 PANTHER PTHR32071:SF33 8 458 3.9E-181 T 22-04-2016 TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 SUPERFAMILY SSF52540 143 385 1.63E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 Pfam PF00158 Sigma-54 interaction domain 144 309 6.6E-66 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 SUPERFAMILY SSF52172 1 187 1.04E-37 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 356 365 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 Pfam PF02954 Bacterial regulatory protein, Fis family 418 454 7.3E-10 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 PANTHER PTHR32071 8 458 3.9E-181 T 22-04-2016 TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 SUPERFAMILY SSF46689 356 453 8.51E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 Gene3D G3DSA:3.40.50.300 140 315 1.1E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 Pfam PF00072 Response regulator receiver domain 6 115 8.3E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 Gene3D G3DSA:1.10.8.60 316 388 2.5E-22 T 22-04-2016 TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 SMART SM00448 4 115 1.6E-31 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 Gene3D G3DSA:3.40.50.2300 5 126 1.6E-31 T 22-04-2016 TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 SMART SM00382 163 306 9.6E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS07085 9b514f0b825b21bac8387681806104f2 460 Gene3D G3DSA:1.10.10.60 414 453 3.1E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS03175 0fe236f9b0c5388591d6ed3e7a772666 280 Gene3D G3DSA:3.40.50.1980 24 141 2.9E-30 T 22-04-2016 TOLA_RS03175 0fe236f9b0c5388591d6ed3e7a772666 280 PANTHER PTHR30535 18 263 9.7E-52 T 22-04-2016 TOLA_RS03175 0fe236f9b0c5388591d6ed3e7a772666 280 Gene3D G3DSA:3.40.50.1980 148 266 2.0E-35 T 22-04-2016 TOLA_RS03175 0fe236f9b0c5388591d6ed3e7a772666 280 SUPERFAMILY SSF53807 24 266 1.73E-60 T 22-04-2016 TOLA_RS03175 0fe236f9b0c5388591d6ed3e7a772666 280 Pfam PF01497 Periplasmic binding protein 27 245 1.6E-27 T 22-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 TOLA_RS04675 5c33e4ac2bf0d67578f60ce5cc147c28 251 Gene3D G3DSA:3.40.50.150 77 212 3.9E-19 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04675 5c33e4ac2bf0d67578f60ce5cc147c28 251 PANTHER PTHR10108:SF836 77 225 2.0E-45 T 22-04-2016 TOLA_RS04675 5c33e4ac2bf0d67578f60ce5cc147c28 251 SUPERFAMILY SSF53335 77 184 9.12E-20 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04675 5c33e4ac2bf0d67578f60ce5cc147c28 251 PANTHER PTHR10108 77 225 2.0E-45 T 22-04-2016 TOLA_RS04675 5c33e4ac2bf0d67578f60ce5cc147c28 251 Pfam PF08241 Methyltransferase domain 77 125 3.1E-9 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 TOLA_RS05290 ceef2a0611d04d59b1d43dd0e1949879 287 SUPERFAMILY SSF103481 185 279 3.92E-10 T 22-04-2016 TOLA_RS05290 ceef2a0611d04d59b1d43dd0e1949879 287 Pfam PF00892 EamA-like transporter family 148 277 5.2E-16 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS05290 ceef2a0611d04d59b1d43dd0e1949879 287 SUPERFAMILY SSF103481 46 136 4.97E-6 T 22-04-2016 TOLA_RS05290 ceef2a0611d04d59b1d43dd0e1949879 287 PANTHER PTHR22911:SF37 7 287 2.7E-85 T 22-04-2016 TOLA_RS05290 ceef2a0611d04d59b1d43dd0e1949879 287 PANTHER PTHR22911 7 287 2.7E-85 T 22-04-2016 TOLA_RS04250 e4b57ee261fb11e5aa30249a92334305 241 Pfam PF01980 Uncharacterised protein family UPF0066 27 149 1.1E-42 T 22-04-2016 IPR023370 TsaA-like domain TOLA_RS04250 e4b57ee261fb11e5aa30249a92334305 241 SUPERFAMILY SSF118196 9 235 2.09E-82 T 22-04-2016 IPR023370 TsaA-like domain TOLA_RS04250 e4b57ee261fb11e5aa30249a92334305 241 PANTHER PTHR12818:SF6 11 237 1.6E-102 T 22-04-2016 TOLA_RS04250 e4b57ee261fb11e5aa30249a92334305 241 PANTHER PTHR12818 11 237 1.6E-102 T 22-04-2016 TOLA_RS04250 e4b57ee261fb11e5aa30249a92334305 241 Gene3D G3DSA:2.40.30.70 10 162 4.0E-53 T 22-04-2016 IPR023370 TsaA-like domain TOLA_RS04250 e4b57ee261fb11e5aa30249a92334305 241 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 9 155 3.2E-53 T 22-04-2016 IPR023370 TsaA-like domain TOLA_RS04250 e4b57ee261fb11e5aa30249a92334305 241 ProSitePatterns PS01318 TsaA-like domain signature. 93 104 - T 22-04-2016 IPR023368 Uncharacterised protein family UPF0066, conserved site TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 Pfam PF13604 AAA domain 172 334 4.9E-30 T 22-04-2016 TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 SUPERFAMILY SSF52540 19 379 7.0E-42 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 Gene3D G3DSA:3.40.50.300 148 337 3.2E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 Gene3D G3DSA:3.40.50.300 369 402 3.2E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 20 622 52.649 T 22-04-2016 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 13 621 9.1E-188 T 22-04-2016 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 SUPERFAMILY SSF52540 300 397 3.45E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 SUPERFAMILY SSF52540 454 622 3.45E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 Pfam PF13538 UvrD-like helicase C-terminal domain 551 595 3.0E-15 T 22-04-2016 IPR027785 UvrD-like helicase C-terminal domain TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 PANTHER PTHR10887:SF351 165 341 5.6E-79 T 22-04-2016 TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 PANTHER PTHR10887:SF351 84 116 5.6E-79 T 22-04-2016 TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 Gene3D G3DSA:3.40.50.300 543 605 8.1E-11 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 PANTHER PTHR10887 165 341 5.6E-79 T 22-04-2016 TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 PANTHER PTHR10887 84 116 5.6E-79 T 22-04-2016 TOLA_RS00330 d23e74c304d39ee91025009007ddf6b6 632 SMART SM00382 181 339 0.0012 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS02630 8416a03e17bcb83ec86d0cbc76712158 157 PANTHER PTHR36918 1 155 2.5E-81 T 22-04-2016 TOLA_RS02630 8416a03e17bcb83ec86d0cbc76712158 157 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 100 122 1.5E-39 T 22-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TOLA_RS02630 8416a03e17bcb83ec86d0cbc76712158 157 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 126 144 1.5E-39 T 22-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TOLA_RS02630 8416a03e17bcb83ec86d0cbc76712158 157 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 76 96 1.5E-39 T 22-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TOLA_RS02630 8416a03e17bcb83ec86d0cbc76712158 157 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 16 33 1.5E-39 T 22-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TOLA_RS02630 8416a03e17bcb83ec86d0cbc76712158 157 Hamap MF_00821 Protein-export protein SecB [secB]. 1 148 32.963 T 22-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TOLA_RS02630 8416a03e17bcb83ec86d0cbc76712158 157 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 10 141 7.7E-61 T 22-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TOLA_RS02630 8416a03e17bcb83ec86d0cbc76712158 157 Pfam PF02556 Preprotein translocase subunit SecB 10 146 2.3E-56 T 22-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TOLA_RS02630 8416a03e17bcb83ec86d0cbc76712158 157 PANTHER PTHR36918:SF1 1 155 2.5E-81 T 22-04-2016 TOLA_RS02630 8416a03e17bcb83ec86d0cbc76712158 157 SUPERFAMILY SSF54611 4 143 5.01E-53 T 22-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TOLA_RS02630 8416a03e17bcb83ec86d0cbc76712158 157 Gene3D G3DSA:3.10.420.10 6 154 4.7E-60 T 22-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 PIRSF PIRSF002583 1 633 2.7E-220 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 Gene3D G3DSA:3.30.565.10 8 245 1.7E-82 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 28 37 - T 22-04-2016 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 PRINTS PR00775 90kDa heat shock protein signature 123 145 1.6E-63 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 PRINTS PR00775 90kDa heat shock protein signature 175 192 1.6E-63 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 PRINTS PR00775 90kDa heat shock protein signature 193 211 1.6E-63 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 PRINTS PR00775 90kDa heat shock protein signature 96 113 1.6E-63 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 PRINTS PR00775 90kDa heat shock protein signature 78 95 1.6E-63 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 PRINTS PR00775 90kDa heat shock protein signature 8 28 1.6E-63 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 PRINTS PR00775 90kDa heat shock protein signature 29 51 1.6E-63 T 22-04-2016 IPR020575 Heat shock protein Hsp90, N-terminal TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 SUPERFAMILY SSF55874 7 215 1.09E-67 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 Pfam PF00183 Hsp90 protein 228 631 5.3E-132 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 SUPERFAMILY SSF110942 520 632 5.89E-34 T 22-04-2016 TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 186 1.6E-14 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 Hamap MF_00505 Chaperone protein HtpG [htpG]. 5 632 32.23 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 PANTHER PTHR11528 7 631 0.0 T 22-04-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 SMART SM00387 30 187 3.0E-8 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 PANTHER PTHR11528:SF44 7 631 0.0 T 22-04-2016 TOLA_RS11240 c75f24b4d85fbdd4ce2c93ae91016c56 633 SUPERFAMILY SSF54211 238 493 8.34E-100 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS12530 93d7059ffb9e520f6243921c6759c4d2 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 5.9E-16 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS12530 93d7059ffb9e520f6243921c6759c4d2 210 PANTHER PTHR30055 5 208 1.6E-21 T 22-04-2016 TOLA_RS12530 93d7059ffb9e520f6243921c6759c4d2 210 SUPERFAMILY SSF48498 96 179 2.82E-10 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TOLA_RS12530 93d7059ffb9e520f6243921c6759c4d2 210 Gene3D G3DSA:1.10.357.10 19 207 1.5E-33 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 TOLA_RS12530 93d7059ffb9e520f6243921c6759c4d2 210 SUPERFAMILY SSF46689 11 91 2.41E-18 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS12530 93d7059ffb9e520f6243921c6759c4d2 210 Pfam PF16859 Bacterial transcriptional repressor C-terminal 99 178 4.9E-10 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TOLA_RS12530 93d7059ffb9e520f6243921c6759c4d2 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.5E-7 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS12530 93d7059ffb9e520f6243921c6759c4d2 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.5E-7 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS00630 0b3d5595e99a2ce9bcc45591afca8eea 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.5E-54 T 22-04-2016 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00630 0b3d5595e99a2ce9bcc45591afca8eea 118 Gene3D G3DSA:1.10.8.50 2 71 1.8E-28 T 22-04-2016 TOLA_RS00630 0b3d5595e99a2ce9bcc45591afca8eea 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 3.0E-33 T 22-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00630 0b3d5595e99a2ce9bcc45591afca8eea 118 SUPERFAMILY SSF46946 2 114 8.54E-47 T 22-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TOLA_RS00630 0b3d5595e99a2ce9bcc45591afca8eea 118 PANTHER PTHR10871 2 118 8.4E-67 T 22-04-2016 TOLA_RS00630 0b3d5595e99a2ce9bcc45591afca8eea 118 PIRSF PIRSF002134 1 118 3.6E-42 T 22-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00630 0b3d5595e99a2ce9bcc45591afca8eea 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 25.743 T 22-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00630 0b3d5595e99a2ce9bcc45591afca8eea 118 Gene3D G3DSA:4.10.910.10 72 118 1.3E-28 T 22-04-2016 IPR027437 30s ribosomal protein S13, C-terminal TOLA_RS00630 0b3d5595e99a2ce9bcc45591afca8eea 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 22-04-2016 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS02095 556804874ceb187ffed81e3e29357bd8 86 Hamap MF_00404 Probable oxaloacetate decarboxylase gamma chain [oadG]. 1 86 30.357 T 22-04-2016 IPR023424 Oxaloacetate decarboxylase gamma chain, probable GO:0008948 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 TOLA_RS02095 556804874ceb187ffed81e3e29357bd8 86 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 5 83 4.3E-16 T 22-04-2016 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 TOLA_RS02095 556804874ceb187ffed81e3e29357bd8 86 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 9 80 3.9E-15 T 22-04-2016 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 TOLA_RS04155 110d406265392d4236f6477fd60bf26b 419 PIRSF PIRSF000151 1 419 4.7E-163 T 22-04-2016 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 TOLA_RS04155 110d406265392d4236f6477fd60bf26b 419 Gene3D G3DSA:3.40.605.10 5 221 5.2E-96 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 TOLA_RS04155 110d406265392d4236f6477fd60bf26b 419 Gene3D G3DSA:3.40.605.10 377 415 5.2E-96 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 TOLA_RS04155 110d406265392d4236f6477fd60bf26b 419 Gene3D G3DSA:3.40.309.10 224 376 1.8E-33 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 TOLA_RS04155 110d406265392d4236f6477fd60bf26b 419 SUPERFAMILY SSF53720 5 411 5.24E-104 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 TOLA_RS04155 110d406265392d4236f6477fd60bf26b 419 Pfam PF00171 Aldehyde dehydrogenase family 8 284 1.5E-14 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 TOLA_RS04155 110d406265392d4236f6477fd60bf26b 419 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 2 418 39.307 T 22-04-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 TOLA_RS04155 110d406265392d4236f6477fd60bf26b 419 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 10 408 1.3E-166 T 22-04-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 TOLA_RS04155 110d406265392d4236f6477fd60bf26b 419 PANTHER PTHR11063:SF8 1 414 2.7E-172 T 22-04-2016 TOLA_RS04155 110d406265392d4236f6477fd60bf26b 419 PANTHER PTHR11063 1 414 2.7E-172 T 22-04-2016 TOLA_RS10490 791fd8043a796e40668736f9d469c559 496 Gene3D G3DSA:3.30.420.40 3 125 1.6E-44 T 22-04-2016 TOLA_RS10490 791fd8043a796e40668736f9d469c559 496 PIRSF PIRSF001267 1 495 4.7E-193 T 22-04-2016 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40|UniPathway: UPA00908 TOLA_RS10490 791fd8043a796e40668736f9d469c559 496 PANTHER PTHR30005 4 493 1.8E-178 T 22-04-2016 TOLA_RS10490 791fd8043a796e40668736f9d469c559 496 Pfam PF02541 Ppx/GppA phosphatase family 20 298 1.6E-77 T 22-04-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40|UniPathway: UPA00908 TOLA_RS10490 791fd8043a796e40668736f9d469c559 496 SUPERFAMILY SSF109604 305 488 1.26E-47 T 22-04-2016 TOLA_RS10490 791fd8043a796e40668736f9d469c559 496 SUPERFAMILY SSF53067 6 126 2.2E-37 T 22-04-2016 TOLA_RS10490 791fd8043a796e40668736f9d469c559 496 Gene3D G3DSA:3.30.420.150 126 301 8.7E-49 T 22-04-2016 TOLA_RS10490 791fd8043a796e40668736f9d469c559 496 SUPERFAMILY SSF53067 130 300 5.96E-43 T 22-04-2016 TOLA_RS10490 791fd8043a796e40668736f9d469c559 496 PANTHER PTHR30005:SF4 4 493 1.8E-178 T 22-04-2016 TOLA_RS10490 791fd8043a796e40668736f9d469c559 496 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 6 297 3.3E-95 T 22-04-2016 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 Gene3D G3DSA:3.40.1190.10 86 313 6.3E-74 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 Pfam PF01225 Mur ligase family, catalytic domain 26 96 7.2E-12 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 Gene3D G3DSA:3.40.1390.10 2 84 9.1E-26 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 Pfam PF08245 Mur ligase middle domain 109 296 8.1E-49 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 SUPERFAMILY SSF53244 317 449 1.08E-35 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 SUPERFAMILY SSF53623 104 314 6.67E-57 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 PANTHER PTHR23135:SF3 15 452 5.8E-158 T 22-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 404 2.1E-11 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 452 34.407 T 22-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 PANTHER PTHR23135 15 452 5.8E-158 T 22-04-2016 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 Gene3D G3DSA:3.90.190.20 316 453 3.1E-42 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 SUPERFAMILY SSF63418 2 100 1.01E-25 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02700 03fa2167ddc19fd5fde8d205dff92a52 459 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 449 7.9E-144 T 22-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS04620 881e6d854f0942ac24cad0dea53c872b 231 PANTHER PTHR30450 1 231 4.7E-115 T 22-04-2016 TOLA_RS04620 881e6d854f0942ac24cad0dea53c872b 231 Gene3D G3DSA:1.10.3720.10 11 222 5.5E-46 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04620 881e6d854f0942ac24cad0dea53c872b 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 220 1.4E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04620 881e6d854f0942ac24cad0dea53c872b 231 SUPERFAMILY SSF161098 11 211 2.75E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04620 881e6d854f0942ac24cad0dea53c872b 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 117 9.0E-21 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 TOLA_RS04620 881e6d854f0942ac24cad0dea53c872b 231 PANTHER PTHR30450:SF4 1 231 4.7E-115 T 22-04-2016 TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 305 2.8E-45 T 22-04-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 5 415 1.3E-139 T 22-04-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 7 155 2.8E-49 T 22-04-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 PANTHER PTHR21089:SF3 271 358 2.5E-127 T 22-04-2016 TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 PANTHER PTHR21089:SF3 71 255 2.5E-127 T 22-04-2016 TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 3 417 30.747 T 22-04-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 SUPERFAMILY SSF51735 162 314 4.44E-31 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 PANTHER PTHR21089 271 358 2.5E-127 T 22-04-2016 TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 PANTHER PTHR21089 71 255 2.5E-127 T 22-04-2016 TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 PIRSF PIRSF000445 2 420 5.9E-155 T 22-04-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 SUPERFAMILY SSF69075 316 417 2.62E-25 T 22-04-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 319 415 1.4E-23 T 22-04-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 SUPERFAMILY SSF69742 2 157 2.75E-48 T 22-04-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 Gene3D G3DSA:3.40.50.720 183 358 8.4E-33 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04205 18d00fb34d171bedee0604b8dd4d8f3f 420 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 98 121 - T 22-04-2016 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 TOLA_RS13390 6d67fb239edfbd7640c3736dcd4dd264 447 PANTHER PTHR11061:SF30 2 446 1.0E-160 T 22-04-2016 TOLA_RS13390 6d67fb239edfbd7640c3736dcd4dd264 447 Gene3D G3DSA:2.40.50.140 3 75 1.3E-21 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13390 6d67fb239edfbd7640c3736dcd4dd264 447 Pfam PF01938 TRAM domain 5 58 7.1E-6 T 22-04-2016 IPR002792 TRAM domain TOLA_RS13390 6d67fb239edfbd7640c3736dcd4dd264 447 SUPERFAMILY SSF53335 73 445 4.54E-83 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS13390 6d67fb239edfbd7640c3736dcd4dd264 447 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 252 446 4.2E-22 T 22-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TOLA_RS13390 6d67fb239edfbd7640c3736dcd4dd264 447 SUPERFAMILY SSF50249 3 58 3.03E-11 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13390 6d67fb239edfbd7640c3736dcd4dd264 447 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 429 439 - T 22-04-2016 IPR030391 RNA methyltransferase TrmA, conserved site TOLA_RS13390 6d67fb239edfbd7640c3736dcd4dd264 447 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 15 439 6.5E-143 T 22-04-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 TOLA_RS13390 6d67fb239edfbd7640c3736dcd4dd264 447 PANTHER PTHR11061 2 446 1.0E-160 T 22-04-2016 TOLA_RS13390 6d67fb239edfbd7640c3736dcd4dd264 447 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 377 408 - T 22-04-2016 IPR030390 RNA methyltransferase TrmA, active site TOLA_RS13390 6d67fb239edfbd7640c3736dcd4dd264 447 Gene3D G3DSA:3.40.50.150 243 444 4.6E-70 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS05205 e2c6de0f791f0ed1f9f67e11a5f3736d 308 Pfam PF00294 pfkB family carbohydrate kinase 1 298 3.0E-77 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB TOLA_RS05205 e2c6de0f791f0ed1f9f67e11a5f3736d 308 Gene3D G3DSA:3.40.1190.20 1 308 5.6E-90 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS05205 e2c6de0f791f0ed1f9f67e11a5f3736d 308 SUPERFAMILY SSF53613 1 303 4.21E-86 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS05205 e2c6de0f791f0ed1f9f67e11a5f3736d 308 PRINTS PR00990 Ribokinase signature 175 190 4.8E-7 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS05205 e2c6de0f791f0ed1f9f67e11a5f3736d 308 PRINTS PR00990 Ribokinase signature 215 226 4.8E-7 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS05205 e2c6de0f791f0ed1f9f67e11a5f3736d 308 PRINTS PR00990 Ribokinase signature 22 41 4.8E-7 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS05205 e2c6de0f791f0ed1f9f67e11a5f3736d 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 244 257 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TOLA_RS05205 e2c6de0f791f0ed1f9f67e11a5f3736d 308 PANTHER PTHR10584:SF161 1 308 7.3E-113 T 22-04-2016 TOLA_RS05205 e2c6de0f791f0ed1f9f67e11a5f3736d 308 PANTHER PTHR10584 1 308 7.3E-113 T 22-04-2016 TOLA_RS05205 e2c6de0f791f0ed1f9f67e11a5f3736d 308 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 27 51 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TOLA_RS01920 cc0b29684a715c770eba57bc482d070b 146 PANTHER PTHR30093:SF9 1 139 1.7E-72 T 22-04-2016 TOLA_RS01920 cc0b29684a715c770eba57bc482d070b 146 PANTHER PTHR30093 1 139 1.7E-72 T 22-04-2016 TOLA_RS01920 cc0b29684a715c770eba57bc482d070b 146 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 28 1.4E-9 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS01920 cc0b29684a715c770eba57bc482d070b 146 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 3 27 2.8E-9 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS01920 cc0b29684a715c770eba57bc482d070b 146 Pfam PF08334 Type II secretion system (T2SS), protein G 31 137 5.1E-38 T 22-04-2016 IPR013545 Type II secretion system protein G TOLA_RS01920 cc0b29684a715c770eba57bc482d070b 146 Gene3D G3DSA:3.30.700.10 9 73 1.0E-8 T 22-04-2016 TOLA_RS01920 cc0b29684a715c770eba57bc482d070b 146 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS01920 cc0b29684a715c770eba57bc482d070b 146 PRINTS PR00813 Bacterial general secretion pathway protein G signature 44 62 1.3E-22 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 TOLA_RS01920 cc0b29684a715c770eba57bc482d070b 146 PRINTS PR00813 Bacterial general secretion pathway protein G signature 8 33 1.3E-22 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 TOLA_RS01920 cc0b29684a715c770eba57bc482d070b 146 SUPERFAMILY SSF54523 34 138 1.2E-37 T 22-04-2016 TOLA_RS01920 cc0b29684a715c770eba57bc482d070b 146 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 7 138 4.1E-56 T 22-04-2016 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 Pfam PF02863 Arginine repressor, C-terminal domain 82 148 1.7E-23 T 22-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 PANTHER PTHR34471 2 156 6.1E-61 T 22-04-2016 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 TIGRFAM TIGR01529 argR_whole: arginine repressor 9 151 1.6E-43 T 22-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 89 153 6.0E-21 T 22-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 PANTHER PTHR34471:SF1 2 156 6.1E-61 T 22-04-2016 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 Pfam PF01316 Arginine repressor, DNA binding domain 6 73 1.6E-21 T 22-04-2016 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 UniPathway: UPA00068 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 SUPERFAMILY SSF46785 6 77 1.18E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 PRINTS PR01467 Bacterial arginine repressor signature 121 136 3.7E-23 T 22-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 PRINTS PR01467 Bacterial arginine repressor signature 90 103 3.7E-23 T 22-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 PRINTS PR01467 Bacterial arginine repressor signature 42 57 3.7E-23 T 22-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 PRINTS PR01467 Bacterial arginine repressor signature 25 38 3.7E-23 T 22-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 Hamap MF_00173 Arginine repressor [argR]. 1 155 58.858 T 22-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 Gene3D G3DSA:1.10.10.10 5 77 1.0E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 SUPERFAMILY SSF55252 82 151 1.57E-20 T 22-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 TOLA_RS12975 2a950c50f39cb91f9074b3cfa728e7b3 156 Gene3D G3DSA:3.30.1360.40 80 153 1.6E-27 T 22-04-2016 IPR024946 Arginine repressor C-terminal-like domain TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 SUPERFAMILY SSF88946 50 157 2.09E-43 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 280 306 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 Pfam PF00140 Sigma-70 factor, region 1.2 50 82 1.4E-7 T 22-04-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 SUPERFAMILY SSF88659 160 234 3.14E-15 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 Gene3D G3DSA:1.10.601.10 35 156 1.7E-53 T 22-04-2016 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 SUPERFAMILY SSF88659 218 315 3.74E-25 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 PANTHER PTHR30603 1 322 7.1E-176 T 22-04-2016 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 111 124 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 Pfam PF04539 Sigma-70 region 3 167 242 1.7E-20 T 22-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 PRINTS PR00046 Major sigma-70 factor signature 280 295 2.0E-27 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 PRINTS PR00046 Major sigma-70 factor signature 295 306 2.0E-27 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 PRINTS PR00046 Major sigma-70 factor signature 111 124 2.0E-27 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 PRINTS PR00046 Major sigma-70 factor signature 259 271 2.0E-27 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 PRINTS PR00046 Major sigma-70 factor signature 135 143 2.0E-27 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 Gene3D G3DSA:1.10.10.10 160 209 1.2E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 Pfam PF04545 Sigma-70, region 4 255 308 2.7E-18 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 PANTHER PTHR30603:SF15 1 322 7.1E-176 T 22-04-2016 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 46 321 1.8E-136 T 22-04-2016 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 Gene3D G3DSA:1.10.10.10 252 315 2.3E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 Pfam PF04542 Sigma-70 region 2 87 156 4.0E-21 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 83 310 7.7E-37 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13975 76c134fa2b1fab618b3e971eca98918b 324 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 4 321 38.755 T 22-04-2016 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS10865 4c2dcdf9a44a22f56463cb184eb2ca34 404 PANTHER PTHR18964 63 402 2.1E-120 T 22-04-2016 TOLA_RS10865 4c2dcdf9a44a22f56463cb184eb2ca34 404 Gene3D G3DSA:1.10.10.10 13 80 3.6E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10865 4c2dcdf9a44a22f56463cb184eb2ca34 404 PANTHER PTHR18964:SF128 63 402 2.1E-120 T 22-04-2016 TOLA_RS10865 4c2dcdf9a44a22f56463cb184eb2ca34 404 Pfam PF00480 ROK family 88 390 2.6E-66 T 22-04-2016 IPR000600 ROK family TOLA_RS10865 4c2dcdf9a44a22f56463cb184eb2ca34 404 SUPERFAMILY SSF46785 13 77 8.24E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10865 4c2dcdf9a44a22f56463cb184eb2ca34 404 Gene3D G3DSA:3.30.420.40 84 222 2.5E-31 T 22-04-2016 TOLA_RS10865 4c2dcdf9a44a22f56463cb184eb2ca34 404 Gene3D G3DSA:3.30.420.40 223 372 6.4E-48 T 22-04-2016 TOLA_RS10865 4c2dcdf9a44a22f56463cb184eb2ca34 404 SUPERFAMILY SSF53067 87 392 3.99E-54 T 22-04-2016 TOLA_RS12025 db0e5625e519284b9ecfbf1698dd87e7 222 PANTHER PTHR22572 2 221 1.9E-45 T 22-04-2016 TOLA_RS12025 db0e5625e519284b9ecfbf1698dd87e7 222 Pfam PF00483 Nucleotidyl transferase 2 127 8.1E-23 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 TOLA_RS12025 db0e5625e519284b9ecfbf1698dd87e7 222 Gene3D G3DSA:3.90.550.10 1 221 7.6E-51 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS12025 db0e5625e519284b9ecfbf1698dd87e7 222 SUPERFAMILY SSF53448 1 220 1.02E-52 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS12185 e334e0cf1d4ad96913aed2b669a8ccdf 79 PANTHER PTHR36154 10 76 4.4E-13 T 22-04-2016 TOLA_RS12185 e334e0cf1d4ad96913aed2b669a8ccdf 79 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 12 62 2.3E-24 T 22-04-2016 IPR010260 Prophage CP4-57 regulatory protein (AlpA) TOLA_RS07135 76fb82a2d73c4cee9c4109cf6fc1ce2e 294 PANTHER PTHR22911:SF64 1 291 2.0E-61 T 22-04-2016 TOLA_RS07135 76fb82a2d73c4cee9c4109cf6fc1ce2e 294 SUPERFAMILY SSF103481 36 138 6.15E-12 T 22-04-2016 TOLA_RS07135 76fb82a2d73c4cee9c4109cf6fc1ce2e 294 PANTHER PTHR22911 1 291 2.0E-61 T 22-04-2016 TOLA_RS07135 76fb82a2d73c4cee9c4109cf6fc1ce2e 294 Pfam PF00892 EamA-like transporter family 156 292 1.2E-14 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS07135 76fb82a2d73c4cee9c4109cf6fc1ce2e 294 Pfam PF00892 EamA-like transporter family 4 135 1.4E-15 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS07135 76fb82a2d73c4cee9c4109cf6fc1ce2e 294 SUPERFAMILY SSF103481 207 292 2.35E-10 T 22-04-2016 TOLA_RS00635 8d3cde054be08cb909f81376ac017443 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 2.8E-55 T 22-04-2016 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00635 8d3cde054be08cb909f81376ac017443 129 PANTHER PTHR11759 11 129 1.7E-73 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00635 8d3cde054be08cb909f81376ac017443 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 32.884 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00635 8d3cde054be08cb909f81376ac017443 129 SUPERFAMILY SSF53137 14 129 4.58E-48 T 22-04-2016 TOLA_RS00635 8d3cde054be08cb909f81376ac017443 129 PIRSF PIRSF002131 1 129 1.0E-52 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00635 8d3cde054be08cb909f81376ac017443 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 22-04-2016 IPR018102 Ribosomal S11, conserved site TOLA_RS00635 8d3cde054be08cb909f81376ac017443 129 Gene3D G3DSA:3.30.420.80 8 129 2.0E-54 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00635 8d3cde054be08cb909f81376ac017443 129 Pfam PF00411 Ribosomal protein S11 19 128 1.5E-52 T 22-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 PRINTS PR00149 Fumarate lyase superfamily signature 251 278 4.6E-18 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 PRINTS PR00149 Fumarate lyase superfamily signature 294 310 4.6E-18 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 4.6E-18 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 4.6E-18 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 ProSitePatterns PS00163 Fumarate lyases signature. 294 303 - T 22-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 Pfam PF00206 Lyase 14 312 3.6E-70 T 22-04-2016 IPR022761 Fumarate lyase, N-terminal TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 Gene3D G3DSA:1.10.275.10 1 119 1.6E-49 T 22-04-2016 IPR024083 Fumarase/histidase, N-terminal TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 Gene3D G3DSA:1.10.40.30 390 445 1.4E-33 T 22-04-2016 TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 PANTHER PTHR11444 4 455 0.0 T 22-04-2016 IPR000362 Fumarate lyase family TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 455 4.5E-145 T 22-04-2016 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 Gene3D G3DSA:1.20.200.10 120 389 4.2E-89 T 22-04-2016 TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 SUPERFAMILY SSF48557 10 454 1.12E-107 T 22-04-2016 IPR008948 L-Aspartase-like GO:0003824 TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 Pfam PF08328 Adenylosuccinate lyase C-terminal 331 445 8.8E-53 T 22-04-2016 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 TOLA_RS11830 5497a2445469e81e846209a9dfe71902 456 PANTHER PTHR11444:SF17 4 455 0.0 T 22-04-2016 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 854 0.0 T 22-04-2016 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747|UniPathway: UPA00223|UniPathway: UPA00946 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 PANTHER PTHR11670 305 860 0.0 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 PIRSF PIRSF036687 1 859 0.0 T 22-04-2016 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747|UniPathway: UPA00223|UniPathway: UPA00946 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 SUPERFAMILY SSF52016 163 372 1.14E-71 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 Pfam PF00330 Aconitase family (aconitate hydratase) 471 818 9.6E-40 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 Gene3D G3DSA:3.30.499.10 402 519 4.3E-64 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 SUPERFAMILY SSF74778 2 160 7.98E-68 T 22-04-2016 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747|UniPathway: UPA00223|UniPathway: UPA00946 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 Pfam PF11791 Aconitate B N-terminal domain 4 156 4.4E-67 T 22-04-2016 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747|UniPathway: UPA00223|UniPathway: UPA00946 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 Gene3D G3DSA:3.30.499.10 684 862 1.3E-54 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 Gene3D G3DSA:3.40.1060.10 520 682 1.4E-84 T 22-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 SUPERFAMILY SSF53732 379 860 5.49E-150 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 ProSitePatterns PS01244 Aconitase family signature 2. 761 774 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 PANTHER PTHR11670:SF39 305 860 0.0 T 22-04-2016 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 382 2.5E-97 T 22-04-2016 IPR015929 Aconitase B, N-terminal GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747|UniPathway: UPA00223|UniPathway: UPA00946 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 ProSitePatterns PS00450 Aconitase family signature 1. 702 719 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS13035 19f67daeefa1a08c3e60a680fd8192fa 865 Gene3D G3DSA:3.20.19.10 163 361 1.0E-93 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel TOLA_RS14475 9d920f064e60c6c87b4c64fac3b9ed97 163 PANTHER PTHR38098:SF1 1 162 1.4E-27 T 22-04-2016 TOLA_RS14475 9d920f064e60c6c87b4c64fac3b9ed97 163 Gene3D G3DSA:3.30.160.150 19 161 1.8E-33 T 22-04-2016 TOLA_RS14475 9d920f064e60c6c87b4c64fac3b9ed97 163 PANTHER PTHR38098 1 162 1.4E-27 T 22-04-2016 TOLA_RS14475 9d920f064e60c6c87b4c64fac3b9ed97 163 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 4 163 18.969 T 22-04-2016 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 TOLA_RS14475 9d920f064e60c6c87b4c64fac3b9ed97 163 Pfam PF04390 Lipopolysaccharide-assembly 11 157 2.3E-12 T 22-04-2016 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 Gene3D G3DSA:3.40.50.300 3 235 5.6E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 Gene3D G3DSA:2.40.50.100 348 361 2.6E-16 T 22-04-2016 TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 Gene3D G3DSA:2.40.50.100 240 288 2.6E-16 T 22-04-2016 TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 Pfam PF00005 ABC transporter 21 162 4.0E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 PANTHER PTHR24220 5 268 5.2E-157 T 22-04-2016 TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 PANTHER PTHR24220 300 336 5.2E-157 T 22-04-2016 TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 SUPERFAMILY SSF52540 4 243 2.73E-85 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 SUPERFAMILY SSF50331 237 362 1.07E-30 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 Pfam PF08402 TOBE domain 282 354 4.2E-9 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 SMART SM00382 29 212 2.5E-17 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 PANTHER PTHR24220:SF448 5 268 5.2E-157 T 22-04-2016 TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 PANTHER PTHR24220:SF448 300 336 5.2E-157 T 22-04-2016 TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 Gene3D G3DSA:2.40.50.140 295 344 1.9E-14 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS06305 4c8181887ac38282fbdbc01b93122a44 371 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS03105 afc5ca4cacaf6010140bfdeacb9130c5 1097 SUPERFAMILY SSF82861 836 920 2.09E-8 T 22-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TOLA_RS03105 afc5ca4cacaf6010140bfdeacb9130c5 1097 PANTHER PTHR30347:SF2 1 1095 0.0 T 22-04-2016 TOLA_RS03105 afc5ca4cacaf6010140bfdeacb9130c5 1097 Gene3D G3DSA:2.30.30.60 937 986 3.8E-17 T 22-04-2016 TOLA_RS03105 afc5ca4cacaf6010140bfdeacb9130c5 1097 Pfam PF00924 Mechanosensitive ion channel 879 1078 1.8E-57 T 22-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TOLA_RS03105 afc5ca4cacaf6010140bfdeacb9130c5 1097 SUPERFAMILY SSF82689 989 1089 5.1E-26 T 22-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TOLA_RS03105 afc5ca4cacaf6010140bfdeacb9130c5 1097 SUPERFAMILY SSF50182 922 987 7.19E-17 T 22-04-2016 IPR010920 LSM domain TOLA_RS03105 afc5ca4cacaf6010140bfdeacb9130c5 1097 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 499 818 5.0E-95 T 22-04-2016 IPR025692 Mechanosensitive ion channel inner membrane domain 1 TOLA_RS03105 afc5ca4cacaf6010140bfdeacb9130c5 1097 Gene3D G3DSA:3.30.70.100 992 1076 1.9E-22 T 22-04-2016 TOLA_RS03105 afc5ca4cacaf6010140bfdeacb9130c5 1097 Pfam PF12795 Mechanosensitive ion channel porin domain 39 276 2.7E-54 T 22-04-2016 IPR024393 Mechanosensitive ion channel MscS, porin domain TOLA_RS03105 afc5ca4cacaf6010140bfdeacb9130c5 1097 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 951 985 - T 22-04-2016 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 TOLA_RS03105 afc5ca4cacaf6010140bfdeacb9130c5 1097 PANTHER PTHR30347 1 1095 0.0 T 22-04-2016 TOLA_RS02035 f9f10a7b8f47056131a8522e2b7f92c8 378 PANTHER PTHR30294 3 375 7.2E-106 T 22-04-2016 TOLA_RS02035 f9f10a7b8f47056131a8522e2b7f92c8 378 Pfam PF12698 ABC-2 family transporter protein 27 370 5.2E-52 T 22-04-2016 TOLA_RS02035 f9f10a7b8f47056131a8522e2b7f92c8 378 PANTHER PTHR30294:SF12 3 375 7.2E-106 T 22-04-2016 TOLA_RS04490 619ed1eb7ddb14a04ae576296e0920ef 299 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 293 2.9E-102 T 22-04-2016 IPR010099 Epimerase family protein SDR39U1 TOLA_RS04490 619ed1eb7ddb14a04ae576296e0920ef 299 PANTHER PTHR11092:SF0 1 299 3.5E-129 T 22-04-2016 TOLA_RS04490 619ed1eb7ddb14a04ae576296e0920ef 299 Gene3D G3DSA:3.40.50.720 1 237 2.7E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04490 619ed1eb7ddb14a04ae576296e0920ef 299 SUPERFAMILY SSF51735 1 298 2.41E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04490 619ed1eb7ddb14a04ae576296e0920ef 299 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 222 3.4E-17 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 TOLA_RS04490 619ed1eb7ddb14a04ae576296e0920ef 299 Pfam PF08338 Domain of unknown function (DUF1731) 250 296 1.4E-23 T 22-04-2016 IPR013549 Domain of unknown function DUF1731 TOLA_RS04490 619ed1eb7ddb14a04ae576296e0920ef 299 PANTHER PTHR11092 1 299 3.5E-129 T 22-04-2016 IPR010099 Epimerase family protein SDR39U1 TOLA_RS07350 a33ee9bc9fef158622b64f5ae9417233 206 TIGRFAM TIGR01298 RNaseT: ribonuclease T 3 201 6.6E-105 T 22-04-2016 IPR005987 Ribonuclease T GO:0004540|GO:0006396 TOLA_RS07350 a33ee9bc9fef158622b64f5ae9417233 206 PANTHER PTHR30231 3 206 5.2E-113 T 22-04-2016 TOLA_RS07350 a33ee9bc9fef158622b64f5ae9417233 206 SUPERFAMILY SSF53098 3 200 1.06E-55 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS07350 a33ee9bc9fef158622b64f5ae9417233 206 SMART SM00479 11 196 1.6E-36 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III TOLA_RS07350 a33ee9bc9fef158622b64f5ae9417233 206 PANTHER PTHR30231:SF2 3 206 5.2E-113 T 22-04-2016 TOLA_RS07350 a33ee9bc9fef158622b64f5ae9417233 206 Hamap MF_00157 Ribonuclease T [rnt]. 1 206 113.592 T 22-04-2016 IPR005987 Ribonuclease T GO:0004540|GO:0006396 TOLA_RS07350 a33ee9bc9fef158622b64f5ae9417233 206 Gene3D G3DSA:3.30.420.10 4 203 9.0E-58 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS07350 a33ee9bc9fef158622b64f5ae9417233 206 Pfam PF00929 Exonuclease 13 187 4.2E-37 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III TOLA_RS11445 4a4a11fb94cc2d71cc28b38126d51eed 209 TIGRFAM TIGR00438 rrmJ: ribosomal RNA large subunit methyltransferase J 20 207 5.4E-91 T 22-04-2016 IPR004512 Ribosomal RNA methyltransferase E, gammaproteobacteria GO:0006364|GO:0016436 KEGG: 00564+2.1.1.16 TOLA_RS11445 4a4a11fb94cc2d71cc28b38126d51eed 209 PIRSF PIRSF005461 1 209 1.8E-81 T 22-04-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 TOLA_RS11445 4a4a11fb94cc2d71cc28b38126d51eed 209 Pfam PF01728 FtsJ-like methyltransferase 31 207 1.2E-57 T 22-04-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 TOLA_RS11445 4a4a11fb94cc2d71cc28b38126d51eed 209 Gene3D G3DSA:3.40.50.150 1 208 4.8E-75 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS11445 4a4a11fb94cc2d71cc28b38126d51eed 209 SUPERFAMILY SSF53335 31 208 2.52E-42 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS11445 4a4a11fb94cc2d71cc28b38126d51eed 209 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 11 207 28.394 T 22-04-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 TOLA_RS11445 4a4a11fb94cc2d71cc28b38126d51eed 209 PANTHER PTHR10920:SF20 1 208 2.6E-137 T 22-04-2016 TOLA_RS11445 4a4a11fb94cc2d71cc28b38126d51eed 209 PANTHER PTHR10920 1 208 2.6E-137 T 22-04-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 TOLA_RS05065 dd025f1e8867a90b9c5878089a6c27dd 115 Gene3D G3DSA:3.40.190.10 9 99 1.5E-14 T 22-04-2016 TOLA_RS05065 dd025f1e8867a90b9c5878089a6c27dd 115 SUPERFAMILY SSF53850 15 97 1.23E-10 T 22-04-2016 TOLA_RS05065 dd025f1e8867a90b9c5878089a6c27dd 115 Pfam PF03466 LysR substrate binding domain 18 100 2.0E-12 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS16295 e62335ab62cbd75270e45e4a5756c601 180 Pfam PF13511 Domain of unknown function (DUF4124) 19 65 2.2E-11 T 22-04-2016 IPR025392 Domain of unknown function DUF4124 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 PANTHER PTHR13789 1 393 3.8E-141 T 22-04-2016 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 Gene3D G3DSA:3.50.50.60 285 324 1.7E-38 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 Gene3D G3DSA:3.50.50.60 7 187 1.7E-38 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 SUPERFAMILY SSF51905 274 386 2.99E-56 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 SUPERFAMILY SSF51905 7 184 2.99E-56 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 Pfam PF01494 FAD binding domain 8 343 1.7E-25 T 22-04-2016 IPR002938 FAD-binding domain GO:0071949 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 9 393 1.1E-121 T 22-04-2016 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 UniPathway: UPA00232 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 1.5E-16 T 22-04-2016 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 1.5E-16 T 22-04-2016 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 1.5E-16 T 22-04-2016 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 1.5E-16 T 22-04-2016 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 TIGRFAM TIGR01984 UbiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase 9 393 4.1E-130 T 22-04-2016 IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase GO:0006744|GO:0008681 KEGG: 00130+1.14.13.-|KEGG: 00140+1.14.13.-|KEGG: 00232+1.14.13.-|KEGG: 00261+1.14.13.-|KEGG: 00340+1.14.13.-|KEGG: 00360+1.14.13.-|KEGG: 00361+1.14.13.-|KEGG: 00362+1.14.13.-|KEGG: 00363+1.14.13.-|KEGG: 00380+1.14.13.-|KEGG: 00403+1.14.13.-|KEGG: 00590+1.14.13.-|KEGG: 00591+1.14.13.-|KEGG: 00622+1.14.13.-|KEGG: 00623+1.14.13.-|KEGG: 00624+1.14.13.-|KEGG: 00625+1.14.13.-|KEGG: 00626+1.14.13.-|KEGG: 00627+1.14.13.-|KEGG: 00640+1.14.13.-|KEGG: 00643+1.14.13.-|KEGG: 00830+1.14.13.-|KEGG: 00903+1.14.13.-|KEGG: 00904+1.14.13.-|KEGG: 00905+1.14.13.-|KEGG: 00906+1.14.13.-|KEGG: 00930+1.14.13.-|KEGG: 00940+1.14.13.-|KEGG: 00941+1.14.13.-|KEGG: 00943+1.14.13.-|KEGG: 00945+1.14.13.-|KEGG: 00950+1.14.13.-|KEGG: 00966+1.14.13.-|KEGG: 00980+1.14.13.-|KEGG: 00982+1.14.13.-|KEGG: 00983+1.14.13.-|UniPathway: UPA00232 TOLA_RS04770 0f2dc94482a0561c5a70bd5762a6c993 396 PANTHER PTHR13789:SF214 1 393 3.8E-141 T 22-04-2016 TOLA_RS08920 3955d7ba14dcfc7c546a616feecc16c7 144 PANTHER PTHR23404 3 137 1.7E-38 T 22-04-2016 TOLA_RS08920 3955d7ba14dcfc7c546a616feecc16c7 144 Pfam PF02391 MoaE protein 7 119 6.1E-37 T 22-04-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS08920 3955d7ba14dcfc7c546a616feecc16c7 144 SUPERFAMILY SSF54690 5 138 1.14E-47 T 22-04-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS08920 3955d7ba14dcfc7c546a616feecc16c7 144 Gene3D G3DSA:3.90.1170.40 4 138 1.1E-51 T 22-04-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS08920 3955d7ba14dcfc7c546a616feecc16c7 144 PANTHER PTHR23404:SF2 3 137 1.7E-38 T 22-04-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS01330 45323cb4ae1ef30b46c8952f86cda169 347 Pfam PF09383 NIL domain 268 339 5.5E-21 T 22-04-2016 IPR018449 NIL domain TOLA_RS01330 45323cb4ae1ef30b46c8952f86cda169 347 TIGRFAM TIGR02314 ABC_MetN: D-methionine ABC transporter, ATP-binding protein 1 343 1.7E-156 T 22-04-2016 IPR012692 ABC transporter, methionine import, ATP-binding protein MetN, proteobacteria GO:0005524|GO:0009276|GO:0048473|GO:0048474 TOLA_RS01330 45323cb4ae1ef30b46c8952f86cda169 347 Pfam PF00005 ABC transporter 21 169 2.6E-34 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS01330 45323cb4ae1ef30b46c8952f86cda169 347 Gene3D G3DSA:3.30.70.260 244 343 1.2E-27 T 22-04-2016 TOLA_RS01330 45323cb4ae1ef30b46c8952f86cda169 347 SMART SM00382 30 224 8.5E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS01330 45323cb4ae1ef30b46c8952f86cda169 347 Gene3D G3DSA:3.40.50.300 1 241 6.8E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01330 45323cb4ae1ef30b46c8952f86cda169 347 SUPERFAMILY SSF55021 248 343 3.32E-24 T 22-04-2016 TOLA_RS01330 45323cb4ae1ef30b46c8952f86cda169 347 SUPERFAMILY SSF52540 1 239 1.65E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01330 45323cb4ae1ef30b46c8952f86cda169 347 PANTHER PTHR24220:SF455 3 339 2.1E-161 T 22-04-2016 IPR026253 Methionine import ATP-binding protein MetN GO:0005524|GO:0015821|GO:0042626 TOLA_RS01330 45323cb4ae1ef30b46c8952f86cda169 347 SMART SM00930 265 340 1.1E-24 T 22-04-2016 IPR018449 NIL domain TOLA_RS01330 45323cb4ae1ef30b46c8952f86cda169 347 PANTHER PTHR24220 3 339 2.1E-161 T 22-04-2016 TOLA_RS01330 45323cb4ae1ef30b46c8952f86cda169 347 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS07950 6bab52ff3842bf4edf488cc78260b233 144 PANTHER PTHR37421:SF1 1 142 1.1E-58 T 22-04-2016 TOLA_RS07950 6bab52ff3842bf4edf488cc78260b233 144 PIRSF PIRSF006173 1 144 2.3E-59 T 22-04-2016 IPR008228 Uncharacterised conserved protein UCP006173 TOLA_RS07950 6bab52ff3842bf4edf488cc78260b233 144 Pfam PF03692 Putative zinc- or iron-chelating domain 23 91 9.6E-7 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein TOLA_RS07950 6bab52ff3842bf4edf488cc78260b233 144 PANTHER PTHR37421 1 142 1.1E-58 T 22-04-2016 TOLA_RS07950 6bab52ff3842bf4edf488cc78260b233 144 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 1 144 36.895 T 22-04-2016 IPR008228 Uncharacterised conserved protein UCP006173 TOLA_RS10545 8ca53f161b89d5b1ee69536f1d3c7871 80 Gene3D G3DSA:3.40.30.10 1 74 1.2E-23 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS10545 8ca53f161b89d5b1ee69536f1d3c7871 80 Pfam PF00462 Glutaredoxin 4 65 2.0E-15 T 22-04-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 TOLA_RS10545 8ca53f161b89d5b1ee69536f1d3c7871 80 PRINTS PR00160 Glutaredoxin signature 4 22 3.3E-10 T 22-04-2016 IPR014025 Glutaredoxin subgroup TOLA_RS10545 8ca53f161b89d5b1ee69536f1d3c7871 80 PRINTS PR00160 Glutaredoxin signature 62 75 3.3E-10 T 22-04-2016 IPR014025 Glutaredoxin subgroup TOLA_RS10545 8ca53f161b89d5b1ee69536f1d3c7871 80 PRINTS PR00160 Glutaredoxin signature 48 61 3.3E-10 T 22-04-2016 IPR014025 Glutaredoxin subgroup TOLA_RS10545 8ca53f161b89d5b1ee69536f1d3c7871 80 PANTHER PTHR10168 1 80 5.7E-24 T 22-04-2016 TOLA_RS10545 8ca53f161b89d5b1ee69536f1d3c7871 80 SUPERFAMILY SSF52833 3 78 2.02E-20 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS10545 8ca53f161b89d5b1ee69536f1d3c7871 80 PANTHER PTHR10168:SF85 1 80 5.7E-24 T 22-04-2016 TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 SMART SM00491 476 605 1.9E-38 T 22-04-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 PANTHER PTHR11472:SF37 1 621 1.6E-189 T 22-04-2016 TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 Gene3D G3DSA:3.40.50.300 456 600 8.6E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 Pfam PF00270 DEAD/DEAH box helicase 33 83 4.0E-5 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 Pfam PF13307 Helicase C-terminal domain 459 618 1.4E-36 T 22-04-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 SUPERFAMILY SSF52540 390 404 1.78E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 SUPERFAMILY SSF52540 38 86 1.78E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 SUPERFAMILY SSF52540 175 250 1.78E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 SUPERFAMILY SSF52540 439 598 1.78E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 SMART SM00487 18 303 0.0064 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 PANTHER PTHR11472 1 621 1.6E-189 T 22-04-2016 TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 Gene3D G3DSA:3.40.50.300 28 111 2.9E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05485 6bdf48a6e1afc065858d46ea26dd30aa 631 Gene3D G3DSA:3.40.50.300 185 243 2.9E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13005 19def7a6c6261990d902ca9082b40f4b 244 SUPERFAMILY SSF52172 3 136 4.13E-32 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS13005 19def7a6c6261990d902ca9082b40f4b 244 SMART SM00448 2 117 7.7E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS13005 19def7a6c6261990d902ca9082b40f4b 244 PANTHER PTHR26402 2 192 4.4E-61 T 22-04-2016 TOLA_RS13005 19def7a6c6261990d902ca9082b40f4b 244 Pfam PF00072 Response regulator receiver domain 4 117 1.3E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS13005 19def7a6c6261990d902ca9082b40f4b 244 PANTHER PTHR26402:SF522 2 192 4.4E-61 T 22-04-2016 TOLA_RS13005 19def7a6c6261990d902ca9082b40f4b 244 PIRSF PIRSF006171 1 234 1.3E-81 T 22-04-2016 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 TOLA_RS13005 19def7a6c6261990d902ca9082b40f4b 244 Gene3D G3DSA:3.40.50.2300 2 148 5.5E-29 T 22-04-2016 TOLA_RS04945 bfb4720d869c1aeecf80eda3306536ed 196 Pfam PF01725 Ham1 family 4 192 8.4E-55 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 TOLA_RS04945 bfb4720d869c1aeecf80eda3306536ed 196 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 196 48.98 T 22-04-2016 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 TOLA_RS04945 bfb4720d869c1aeecf80eda3306536ed 196 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 194 1.3E-57 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 TOLA_RS04945 bfb4720d869c1aeecf80eda3306536ed 196 Gene3D G3DSA:3.90.950.10 1 196 4.5E-78 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like TOLA_RS04945 bfb4720d869c1aeecf80eda3306536ed 196 PANTHER PTHR11067 1 196 5.8E-81 T 22-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 TOLA_RS04945 bfb4720d869c1aeecf80eda3306536ed 196 PANTHER PTHR11067:SF9 1 196 5.8E-81 T 22-04-2016 TOLA_RS04945 bfb4720d869c1aeecf80eda3306536ed 196 SUPERFAMILY SSF52972 1 195 4.97E-71 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like TOLA_RS08445 ea4daaa180fe7bdab01f65bcdcd2d6d2 179 Gene3D G3DSA:3.30.420.130 1 98 9.5E-18 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS08445 ea4daaa180fe7bdab01f65bcdcd2d6d2 179 SUPERFAMILY SSF53146 1 108 2.88E-17 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS08445 ea4daaa180fe7bdab01f65bcdcd2d6d2 179 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 9 94 3.5E-11 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS01105 39e1ae28419c94bdbc26138d0ed5c379 1173 SUPERFAMILY SSF52540 125 318 1.41E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01105 39e1ae28419c94bdbc26138d0ed5c379 1173 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 18 1170 6.2E-299 T 22-04-2016 IPR017731 Type VI secretion system, IcmF TOLA_RS01105 39e1ae28419c94bdbc26138d0ed5c379 1173 Pfam PF14331 ImcF-related N-terminal domain 199 453 6.4E-74 T 22-04-2016 IPR025743 ImcF-related, N-terminal domain TOLA_RS01105 39e1ae28419c94bdbc26138d0ed5c379 1173 PANTHER PTHR36153 1 1173 1.4E-249 T 22-04-2016 TOLA_RS01105 39e1ae28419c94bdbc26138d0ed5c379 1173 PANTHER PTHR36153:SF1 1 1173 1.4E-249 T 22-04-2016 TOLA_RS01105 39e1ae28419c94bdbc26138d0ed5c379 1173 Pfam PF06761 Intracellular multiplication and human macrophage-killing 503 794 7.9E-67 T 22-04-2016 IPR009612 ImcF-related TOLA_RS01105 39e1ae28419c94bdbc26138d0ed5c379 1173 Pfam PF06744 Type VI secretion protein IcmF C-terminal 922 1121 2.5E-54 T 22-04-2016 IPR010623 Type VI secretion system IcmF, C-terminal TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 SUPERFAMILY SSF52518 350 528 2.06E-68 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 SUPERFAMILY SSF52518 5 321 6.12E-123 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 334 4.2E-169 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 Pfam PF02780 Transketolase, C-terminal domain 541 656 4.3E-18 T 22-04-2016 IPR033248 Transketolase, C-terminal domain TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 Gene3D G3DSA:3.40.50.970 328 533 3.7E-81 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 SMART SM00861 355 526 2.3E-68 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 PANTHER PTHR11624:SF1 1 310 0.0 T 22-04-2016 TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 PANTHER PTHR11624:SF1 341 665 0.0 T 22-04-2016 TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 TIGRFAM TIGR00232 tktlase_bact: transketolase 5 663 0.0 T 22-04-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 Pfam PF02779 Transketolase, pyrimidine binding domain 354 525 7.7E-47 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 Gene3D G3DSA:3.40.50.970 5 322 3.4E-135 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 ProSitePatterns PS00802 Transketolase signature 2. 468 484 - T 22-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 PANTHER PTHR11624 1 310 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 PANTHER PTHR11624 341 665 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 SUPERFAMILY SSF52922 534 665 2.09E-43 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS06420 f84d1284e3f161f1df7d99f28a379149 666 Gene3D G3DSA:3.40.50.920 539 664 3.5E-49 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS00275 8389e7603aeb05e1dbeb611e0393dacb 286 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 3 286 7.8E-82 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TOLA_RS00275 8389e7603aeb05e1dbeb611e0393dacb 286 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 131 142 - T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TOLA_RS00275 8389e7603aeb05e1dbeb611e0393dacb 286 SUPERFAMILY SSF51569 1 286 1.36E-87 T 22-04-2016 TOLA_RS00275 8389e7603aeb05e1dbeb611e0393dacb 286 PANTHER PTHR30304 1 286 6.2E-87 T 22-04-2016 TOLA_RS00275 8389e7603aeb05e1dbeb611e0393dacb 286 PIRSF PIRSF001359 1 286 1.2E-99 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TOLA_RS00275 8389e7603aeb05e1dbeb611e0393dacb 286 Gene3D G3DSA:3.20.20.70 1 286 6.2E-98 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS00275 8389e7603aeb05e1dbeb611e0393dacb 286 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 285 1.5E-92 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 495 40.684 T 22-04-2016 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 Gene3D G3DSA:3.40.220.10 1 161 7.5E-66 T 22-04-2016 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 347 354 - T 22-04-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 186 486 2.0E-120 T 22-04-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 PRINTS PR00481 Cytosol aminopeptidase signature 284 305 1.0E-55 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 PRINTS PR00481 Cytosol aminopeptidase signature 343 363 1.0E-55 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 PRINTS PR00481 Cytosol aminopeptidase signature 262 279 1.0E-55 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 PRINTS PR00481 Cytosol aminopeptidase signature 371 386 1.0E-55 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 PRINTS PR00481 Cytosol aminopeptidase signature 321 342 1.0E-55 T 22-04-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 Gene3D G3DSA:3.40.630.10 171 494 2.6E-139 T 22-04-2016 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 147 1.2E-32 T 22-04-2016 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 SUPERFAMILY SSF52949 1 184 3.3E-51 T 22-04-2016 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 SUPERFAMILY SSF53187 180 493 2.39E-124 T 22-04-2016 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 PANTHER PTHR11963:SF13 7 500 3.1E-257 T 22-04-2016 TOLA_RS02845 0523cab537ab644aea0be518a06ca2ee 500 PANTHER PTHR11963 7 500 3.1E-257 T 22-04-2016 TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 SUPERFAMILY SSF53187 303 380 5.43E-60 T 22-04-2016 TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 SUPERFAMILY SSF53187 5 178 5.43E-60 T 22-04-2016 TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 Gene3D G3DSA:3.40.630.10 321 380 9.8E-65 T 22-04-2016 TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 Gene3D G3DSA:3.40.630.10 5 187 9.8E-65 T 22-04-2016 TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 PANTHER PTHR11014:SF75 1 380 3.3E-170 T 22-04-2016 TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 PANTHER PTHR11014 1 380 3.3E-170 T 22-04-2016 TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 SUPERFAMILY SSF55031 179 291 3.44E-21 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 108 145 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 Pfam PF01546 Peptidase family M20/M25/M40 74 377 8.4E-33 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 Gene3D G3DSA:3.30.70.360 188 288 4.7E-26 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 Hamap MF_01108 Acetylornithine deacetylase [argE]. 1 381 59.65 T 22-04-2016 IPR010169 Acetylornithine deacetylase (ArgE) GO:0005737|GO:0006526|GO:0008270|GO:0008777|GO:0050897 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154|UniPathway: UPA00068 TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 9 376 3.2E-136 T 22-04-2016 IPR010169 Acetylornithine deacetylase (ArgE) GO:0005737|GO:0006526|GO:0008270|GO:0008777|GO:0050897 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154|UniPathway: UPA00068 TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 73 82 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TOLA_RS00490 c0b27e52fda11380ba6ae038caf593dc 381 Pfam PF07687 Peptidase dimerisation domain 176 285 1.1E-23 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain TOLA_RS10540 c0fa070b01d613d56d13c8e962c6600d 84 PANTHER PTHR24960:SF38 1 73 3.2E-24 T 22-04-2016 TOLA_RS10540 c0fa070b01d613d56d13c8e962c6600d 84 Gene3D G3DSA:3.30.70.20 4 71 3.1E-18 T 22-04-2016 TOLA_RS10540 c0fa070b01d613d56d13c8e962c6600d 84 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS10540 c0fa070b01d613d56d13c8e962c6600d 84 PANTHER PTHR24960 1 73 3.2E-24 T 22-04-2016 TOLA_RS10540 c0fa070b01d613d56d13c8e962c6600d 84 Pfam PF00037 4Fe-4S binding domain 5 25 1.2E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TOLA_RS10540 c0fa070b01d613d56d13c8e962c6600d 84 SUPERFAMILY SSF54862 5 72 7.33E-19 T 22-04-2016 TOLA_RS10710 d5d5741ad26dbaa7cecc0b05e62cfa3d 281 PANTHER PTHR13773 1 280 4.3E-64 T 22-04-2016 TOLA_RS10710 d5d5741ad26dbaa7cecc0b05e62cfa3d 281 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 238 264 - T 22-04-2016 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00557 TOLA_RS10710 d5d5741ad26dbaa7cecc0b05e62cfa3d 281 PANTHER PTHR13773:SF0 1 280 4.3E-64 T 22-04-2016 TOLA_RS10710 d5d5741ad26dbaa7cecc0b05e62cfa3d 281 Pfam PF01148 Cytidylyltransferase family 2 277 8.1E-61 T 22-04-2016 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 430 40.597 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 SUPERFAMILY SSF46589 1 112 4.34E-29 T 22-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 425 3.6E-172 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 233 408 2.6E-37 T 22-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 PANTHER PTHR11778 1 431 1.0E-214 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 PIRSF PIRSF001529 1 432 1.8E-178 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 Gene3D G3DSA:1.10.287.40 1 104 3.1E-25 T 22-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 PANTHER PTHR11778:SF0 1 431 1.0E-214 T 22-04-2016 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 SUPERFAMILY SSF55681 116 427 1.99E-103 T 22-04-2016 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 1.6E-27 T 22-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 PRINTS PR00981 Seryl-tRNA synthetase signature 360 376 1.1E-36 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 PRINTS PR00981 Seryl-tRNA synthetase signature 273 285 1.1E-36 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 PRINTS PR00981 Seryl-tRNA synthetase signature 325 338 1.1E-36 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 PRINTS PR00981 Seryl-tRNA synthetase signature 285 298 1.1E-36 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 PRINTS PR00981 Seryl-tRNA synthetase signature 342 358 1.1E-36 T 22-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 TOLA_RS11745 1c096a55fe1ef4c14f88118321737e97 432 Gene3D G3DSA:3.30.930.10 105 428 2.7E-145 T 22-04-2016 TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 335 405 6.5E-6 T 22-04-2016 IPR019489 Clp ATPase, C-terminal TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 443 1.9E-219 T 22-04-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 Gene3D G3DSA:3.40.50.300 3 110 3.5E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 Gene3D G3DSA:3.40.50.300 245 331 3.5E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 Gene3D G3DSA:1.10.8.60 335 443 5.0E-34 T 22-04-2016 TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 135 7.0E-7 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 SUPERFAMILY SSF52540 3 441 6.29E-92 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 SMART SM00382 49 332 1.4E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 Gene3D G3DSA:1.10.8.10 111 177 1.6E-33 T 22-04-2016 TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 Gene3D G3DSA:1.10.8.10 213 242 1.6E-33 T 22-04-2016 TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 Pfam PF07724 AAA domain (Cdc48 subfamily) 172 329 1.2E-38 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 PANTHER PTHR11262:SF3 1 105 4.8E-205 T 22-04-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 PANTHER PTHR11262:SF3 218 443 4.8E-205 T 22-04-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 SMART SM01086 335 429 3.5E-20 T 22-04-2016 IPR019489 Clp ATPase, C-terminal TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 443 42.606 T 22-04-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 PANTHER PTHR11262 1 105 4.8E-205 T 22-04-2016 TOLA_RS02435 104e8aa69d63e0407f8ef6019c09f871 443 PANTHER PTHR11262 218 443 4.8E-205 T 22-04-2016 TOLA_RS03030 e47c12146e638fae5f552dd42a62c20f 678 Pfam PF00795 Carbon-nitrogen hydrolase 7 249 1.3E-16 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS03030 e47c12146e638fae5f552dd42a62c20f 678 Pfam PF02540 NAD synthase 332 591 1.5E-24 T 22-04-2016 IPR022310 NAD/GMP synthase TOLA_RS03030 e47c12146e638fae5f552dd42a62c20f 678 Gene3D G3DSA:3.60.110.10 5 266 3.2E-38 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS03030 e47c12146e638fae5f552dd42a62c20f 678 SUPERFAMILY SSF56317 4 276 8.5E-42 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS03030 e47c12146e638fae5f552dd42a62c20f 678 Gene3D G3DSA:3.40.50.620 404 645 2.2E-55 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS03030 e47c12146e638fae5f552dd42a62c20f 678 Gene3D G3DSA:3.40.50.620 306 371 2.2E-55 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS03030 e47c12146e638fae5f552dd42a62c20f 678 TIGRFAM TIGR00552 nadE: NAD+ synthetase 420 597 5.7E-21 T 22-04-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 TOLA_RS03030 e47c12146e638fae5f552dd42a62c20f 678 PANTHER PTHR23090:SF9 2 678 1.5E-145 T 22-04-2016 TOLA_RS03030 e47c12146e638fae5f552dd42a62c20f 678 PANTHER PTHR23090 2 678 1.5E-145 T 22-04-2016 TOLA_RS03030 e47c12146e638fae5f552dd42a62c20f 678 PIRSF PIRSF006630 2 666 8.3E-139 T 22-04-2016 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|UniPathway: UPA00253 TOLA_RS03030 e47c12146e638fae5f552dd42a62c20f 678 SUPERFAMILY SSF52402 396 645 1.21E-46 T 22-04-2016 TOLA_RS03030 e47c12146e638fae5f552dd42a62c20f 678 SUPERFAMILY SSF52402 317 365 1.21E-46 T 22-04-2016 TOLA_RS01185 7e95198baf878282b87f2bd6ee04b61f 511 SUPERFAMILY SSF53590 47 181 4.71E-8 T 22-04-2016 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain TOLA_RS01185 7e95198baf878282b87f2bd6ee04b61f 511 PANTHER PTHR33307:SF1 1 222 4.7E-34 T 22-04-2016 TOLA_RS01185 7e95198baf878282b87f2bd6ee04b61f 511 PANTHER PTHR33307 1 222 4.7E-34 T 22-04-2016 TOLA_RS01185 7e95198baf878282b87f2bd6ee04b61f 511 Pfam PF07632 Protein of unknown function (DUF1593) 47 314 2.9E-97 T 22-04-2016 IPR011483 Protein of unknown function DUF1593 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 SUPERFAMILY SSF51735 1 167 7.49E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 PANTHER PTHR32092 1 438 6.9E-214 T 22-04-2016 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 Gene3D G3DSA:3.90.110.10 167 436 8.4E-82 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 194 408 3.1E-64 T 22-04-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 SUPERFAMILY SSF56327 168 437 1.1E-73 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 Gene3D G3DSA:3.40.50.720 1 163 1.9E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 Pfam PF02056 Family 4 glycosyl hydrolase 2 184 2.0E-62 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 PANTHER PTHR32092:SF6 1 438 6.9E-214 T 22-04-2016 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 1.11E-34 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 1.11E-34 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 1.11E-34 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 190 202 1.11E-34 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 1.11E-34 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 93 106 1.11E-34 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10795 cc0b16e52b4bf80c7d7f821125dccbbe 438 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 1.11E-34 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS15200 7b11eb892de4b8db0517d70e803c7dab 219 SUPERFAMILY SSF52980 2 216 2.79E-70 T 22-04-2016 IPR011335 Restriction endonuclease type II-like TOLA_RS15200 7b11eb892de4b8db0517d70e803c7dab 219 TIGRFAM TIGR02248 mutH_TIGR: DNA mismatch repair endonuclease MutH 3 216 9.8E-93 T 22-04-2016 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 TOLA_RS15200 7b11eb892de4b8db0517d70e803c7dab 219 SMART SM00927 50 148 9.0E-51 T 22-04-2016 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 TOLA_RS15200 7b11eb892de4b8db0517d70e803c7dab 219 Gene3D G3DSA:3.40.600.10 2 216 3.7E-72 T 22-04-2016 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 TOLA_RS15200 7b11eb892de4b8db0517d70e803c7dab 219 Hamap MF_00759 DNA mismatch repair protein MutH [mutH]. 1 219 119.344 T 22-04-2016 IPR004230 DNA mismatch repair protein MutH GO:0003677|GO:0004519|GO:0006304 TOLA_RS15200 7b11eb892de4b8db0517d70e803c7dab 219 Pfam PF02976 DNA mismatch repair enzyme MutH 50 148 1.8E-32 T 22-04-2016 IPR011337 DNA mismatch repair MutH/Restriction endonuclease, type II GO:0003677|GO:0004519 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 Gene3D G3DSA:3.40.190.10 28 147 9.2E-22 T 22-04-2016 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 PRINTS PR00181 Maltose binding protein signature 148 167 5.9E-87 T 22-04-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 PRINTS PR00181 Maltose binding protein signature 67 85 5.9E-87 T 22-04-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 PRINTS PR00181 Maltose binding protein signature 168 187 5.9E-87 T 22-04-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 PRINTS PR00181 Maltose binding protein signature 127 146 5.9E-87 T 22-04-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 PRINTS PR00181 Maltose binding protein signature 296 317 5.9E-87 T 22-04-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 PRINTS PR00181 Maltose binding protein signature 33 51 5.9E-87 T 22-04-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 PRINTS PR00181 Maltose binding protein signature 354 373 5.9E-87 T 22-04-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 PRINTS PR00181 Maltose binding protein signature 230 249 5.9E-87 T 22-04-2016 IPR006060 Maltose binding protein GO:0005363|GO:0015768 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 PANTHER PTHR30061:SF21 1 393 2.2E-126 T 22-04-2016 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 Gene3D G3DSA:3.40.190.10 148 319 4.9E-55 T 22-04-2016 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 PANTHER PTHR30061 1 393 2.2E-126 T 22-04-2016 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 SUPERFAMILY SSF53850 26 392 3.62E-88 T 22-04-2016 TOLA_RS00215 d752a5f48011d248621951d5d362e4fd 393 Pfam PF13416 Bacterial extracellular solute-binding protein 47 323 1.1E-37 T 22-04-2016 TOLA_RS10755 7c8640eddf2fd5d895532550015851b8 339 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 59 318 1.2E-24 T 22-04-2016 IPR001761 Periplasmic binding protein/LacI sugar binding domain TOLA_RS10755 7c8640eddf2fd5d895532550015851b8 339 Gene3D G3DSA:3.40.50.2300 53 174 2.1E-26 T 22-04-2016 TOLA_RS10755 7c8640eddf2fd5d895532550015851b8 339 Gene3D G3DSA:3.40.50.2300 175 313 2.8E-31 T 22-04-2016 TOLA_RS10755 7c8640eddf2fd5d895532550015851b8 339 Gene3D G3DSA:1.10.260.40 1 52 4.9E-19 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS10755 7c8640eddf2fd5d895532550015851b8 339 SMART SM00354 1 70 1.1E-21 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS10755 7c8640eddf2fd5d895532550015851b8 339 SUPERFAMILY SSF47413 2 58 7.5E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS10755 7c8640eddf2fd5d895532550015851b8 339 SUPERFAMILY SSF53822 57 323 2.36E-40 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS10755 7c8640eddf2fd5d895532550015851b8 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 3.0E-10 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS10755 7c8640eddf2fd5d895532550015851b8 339 PANTHER PTHR30146 1 334 5.8E-68 T 22-04-2016 TOLA_RS13885 e1eade5651a0ae78154bc4f807710d02 517 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 69 461 1.9E-91 T 22-04-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 TOLA_RS13885 e1eade5651a0ae78154bc4f807710d02 517 PANTHER PTHR38686 6 517 4.4E-94 T 22-04-2016 TOLA_RS13885 e1eade5651a0ae78154bc4f807710d02 517 Pfam PF00795 Carbon-nitrogen hydrolase 227 479 5.8E-27 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS13885 e1eade5651a0ae78154bc4f807710d02 517 SUPERFAMILY SSF56317 221 493 5.76E-35 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS13885 e1eade5651a0ae78154bc4f807710d02 517 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 14 498 22.412 T 22-04-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 TOLA_RS13885 e1eade5651a0ae78154bc4f807710d02 517 Gene3D G3DSA:3.60.110.10 218 491 6.3E-22 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS03365 c3bde3851c0e312850a281f3d8ecf671 70 SUPERFAMILY SSF159203 2 67 2.48E-18 T 22-04-2016 IPR024044 NifT/FixU barrel-like domain TOLA_RS03365 c3bde3851c0e312850a281f3d8ecf671 70 TIGRFAM TIGR02934 nifT_nitrog: probable nitrogen fixation protein FixT 4 67 4.0E-14 T 22-04-2016 IPR009727 NifT/FixU GO:0009399 TOLA_RS03365 c3bde3851c0e312850a281f3d8ecf671 70 Pfam PF06988 NifT/FixU protein 1 64 1.5E-20 T 22-04-2016 IPR009727 NifT/FixU GO:0009399 TOLA_RS03365 c3bde3851c0e312850a281f3d8ecf671 70 Gene3D G3DSA:2.40.50.240 2 67 4.2E-21 T 22-04-2016 IPR024044 NifT/FixU barrel-like domain TOLA_RS08925 9766c2367d0c4dd5ccfca36ae6cfed1e 80 PANTHER PTHR33359 1 80 1.1E-24 T 22-04-2016 TOLA_RS08925 9766c2367d0c4dd5ccfca36ae6cfed1e 80 Gene3D G3DSA:3.10.20.30 1 80 2.4E-24 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS08925 9766c2367d0c4dd5ccfca36ae6cfed1e 80 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 1 80 2.0E-20 T 22-04-2016 IPR010034 Molybdopterin converting factor, subunit 1 GO:0006777 UniPathway: UPA00344 TOLA_RS08925 9766c2367d0c4dd5ccfca36ae6cfed1e 80 SUPERFAMILY SSF54285 1 80 6.92E-23 T 22-04-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TOLA_RS08925 9766c2367d0c4dd5ccfca36ae6cfed1e 80 Pfam PF02597 ThiS family 3 80 2.0E-20 T 22-04-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 SMART SM01130 1 288 6.5E-137 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 PIRSF PIRSF001365 1 290 6.0E-87 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 Gene3D G3DSA:3.20.20.70 1 290 4.6E-113 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 286 61.362 T 22-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 7.1E-30 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 127 144 7.1E-30 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 102 118 7.1E-30 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 70 88 7.1E-30 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 286 3.4E-94 T 22-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 Pfam PF00701 Dihydrodipicolinate synthetase family 3 286 1.1E-87 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 PANTHER PTHR12128:SF34 1 290 1.6E-116 T 22-04-2016 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 SUPERFAMILY SSF51569 2 287 1.99E-100 T 22-04-2016 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 132 162 - T 22-04-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 PANTHER PTHR12128 1 290 1.6E-116 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS13310 1a8d1335ad44bdce7e2a92e75ca184dc 290 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 37 54 - T 22-04-2016 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS01900 b1afb41ab459e40833dd17590ec543fe 327 PANTHER PTHR38831 1 325 2.0E-59 T 22-04-2016 TOLA_RS01900 b1afb41ab459e40833dd17590ec543fe 327 Gene3D G3DSA:1.10.40.60 217 279 2.3E-21 T 22-04-2016 TOLA_RS01900 b1afb41ab459e40833dd17590ec543fe 327 Gene3D G3DSA:3.30.1300.30 25 98 4.2E-27 T 22-04-2016 TOLA_RS01900 b1afb41ab459e40833dd17590ec543fe 327 Gene3D G3DSA:3.30.1300.30 286 326 4.2E-27 T 22-04-2016 TOLA_RS01900 b1afb41ab459e40833dd17590ec543fe 327 Pfam PF03934 Type II secretion system (T2SS), protein K 29 318 2.2E-85 T 22-04-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 TOLA_RS01900 b1afb41ab459e40833dd17590ec543fe 327 Gene3D G3DSA:1.10.40.60 100 215 8.5E-40 T 22-04-2016 TOLA_RS01900 b1afb41ab459e40833dd17590ec543fe 327 PANTHER PTHR38831:SF1 1 325 2.0E-59 T 22-04-2016 TOLA_RS01900 b1afb41ab459e40833dd17590ec543fe 327 SUPERFAMILY SSF158544 101 214 3.66E-33 T 22-04-2016 TOLA_RS01900 b1afb41ab459e40833dd17590ec543fe 327 SUPERFAMILY SSF158544 217 274 3.92E-17 T 22-04-2016 TOLA_RS01900 b1afb41ab459e40833dd17590ec543fe 327 PIRSF PIRSF002786 1 326 3.3E-80 T 22-04-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 TOLA_RS01900 b1afb41ab459e40833dd17590ec543fe 327 SUPERFAMILY SSF54523 285 325 5.34E-30 T 22-04-2016 TOLA_RS01900 b1afb41ab459e40833dd17590ec543fe 327 SUPERFAMILY SSF54523 35 100 5.34E-30 T 22-04-2016 TOLA_RS09580 b360fcc24448db292961ddff4091b1ef 299 PANTHER PTHR11019:SF123 150 297 2.4E-42 T 22-04-2016 TOLA_RS09580 b360fcc24448db292961ddff4091b1ef 299 SMART SM00342 206 289 1.7E-30 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS09580 b360fcc24448db292961ddff4091b1ef 299 PANTHER PTHR11019 150 297 2.4E-42 T 22-04-2016 TOLA_RS09580 b360fcc24448db292961ddff4091b1ef 299 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 273 1.7E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS09580 b360fcc24448db292961ddff4091b1ef 299 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 273 289 1.7E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS09580 b360fcc24448db292961ddff4091b1ef 299 Pfam PF12833 Helix-turn-helix domain 214 290 2.8E-19 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS09580 b360fcc24448db292961ddff4091b1ef 299 SUPERFAMILY SSF46689 243 292 7.53E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09580 b360fcc24448db292961ddff4091b1ef 299 Gene3D G3DSA:1.10.10.60 244 293 1.7E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09580 b360fcc24448db292961ddff4091b1ef 299 SUPERFAMILY SSF46689 189 240 1.75E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09580 b360fcc24448db292961ddff4091b1ef 299 Gene3D G3DSA:1.10.10.60 187 242 2.0E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09580 b360fcc24448db292961ddff4091b1ef 299 Pfam PF10114 Sensory domain found in PocR 7 164 2.7E-41 T 22-04-2016 IPR018771 PocR domain UniPathway: UPA00148|UniPathway: UPA00621 TOLA_RS05330 7cea80c1f530ad243e44e3768804a18b 468 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 407 424 - T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS05330 7cea80c1f530ad243e44e3768804a18b 468 Pfam PF00367 phosphotransferase system, EIIB 397 429 3.2E-13 T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS05330 7cea80c1f530ad243e44e3768804a18b 468 PANTHER PTHR30009:SF2 5 468 3.3E-156 T 22-04-2016 TOLA_RS05330 7cea80c1f530ad243e44e3768804a18b 468 Gene3D G3DSA:3.30.1360.60 391 465 6.2E-26 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS05330 7cea80c1f530ad243e44e3768804a18b 468 PANTHER PTHR30009 5 468 3.3E-156 T 22-04-2016 TOLA_RS05330 7cea80c1f530ad243e44e3768804a18b 468 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 371 453 1.8E-21 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS05330 7cea80c1f530ad243e44e3768804a18b 468 SUPERFAMILY SSF55604 394 463 4.84E-20 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS05330 7cea80c1f530ad243e44e3768804a18b 468 Pfam PF02378 Phosphotransferase system, EIIC 12 312 4.7E-56 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS00425 79440b2640f5161a57d87c6b9aaf702a 620 PANTHER PTHR16254 1 562 2.1E-220 T 22-04-2016 TOLA_RS00425 79440b2640f5161a57d87c6b9aaf702a 620 PANTHER PTHR16254:SF6 1 562 2.1E-220 T 22-04-2016 TOLA_RS00425 79440b2640f5161a57d87c6b9aaf702a 620 Pfam PF00999 Sodium/hydrogen exchanger family 11 377 6.8E-65 T 22-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TOLA_RS00425 79440b2640f5161a57d87c6b9aaf702a 620 Pfam PF02254 TrkA-N domain 408 520 2.1E-24 T 22-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TOLA_RS00425 79440b2640f5161a57d87c6b9aaf702a 620 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 13 288 9.8E-83 T 22-04-2016 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 TOLA_RS00425 79440b2640f5161a57d87c6b9aaf702a 620 Gene3D G3DSA:3.40.50.720 400 532 1.3E-34 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00425 79440b2640f5161a57d87c6b9aaf702a 620 SUPERFAMILY SSF51735 406 531 1.67E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS08260 ff0e52a99b57d812f8e9ff986a27019e 280 PANTHER PTHR33643 11 209 3.7E-37 T 22-04-2016 TOLA_RS08260 ff0e52a99b57d812f8e9ff986a27019e 280 Hamap MF_01384 Urease accessory protein UreD [ureD]. 15 264 29.95 T 22-04-2016 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 TOLA_RS08260 ff0e52a99b57d812f8e9ff986a27019e 280 PANTHER PTHR33643:SF1 11 209 3.7E-37 T 22-04-2016 TOLA_RS08260 ff0e52a99b57d812f8e9ff986a27019e 280 Pfam PF01774 UreD urease accessory protein 56 253 5.6E-48 T 22-04-2016 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 TOLA_RS08390 76ffcbb584a1acfa7856b8418c4e49dc 543 PRINTS PR00878 Cholinesterase signature 143 172 3.8E-5 T 22-04-2016 IPR000997 Cholinesterase GO:0004104 TOLA_RS08390 76ffcbb584a1acfa7856b8418c4e49dc 543 PRINTS PR00878 Cholinesterase signature 451 463 3.8E-5 T 22-04-2016 IPR000997 Cholinesterase GO:0004104 TOLA_RS08390 76ffcbb584a1acfa7856b8418c4e49dc 543 Gene3D G3DSA:3.40.50.1820 48 542 2.9E-143 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS08390 76ffcbb584a1acfa7856b8418c4e49dc 543 PANTHER PTHR11559 54 541 1.6E-156 T 22-04-2016 TOLA_RS08390 76ffcbb584a1acfa7856b8418c4e49dc 543 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 118 128 - T 22-04-2016 IPR019819 Carboxylesterase type B, conserved site TOLA_RS08390 76ffcbb584a1acfa7856b8418c4e49dc 543 Pfam PF00135 Carboxylesterase family 52 534 1.1E-115 T 22-04-2016 IPR002018 Carboxylesterase, type B TOLA_RS08390 76ffcbb584a1acfa7856b8418c4e49dc 543 SUPERFAMILY SSF53474 52 540 1.52E-121 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS08390 76ffcbb584a1acfa7856b8418c4e49dc 543 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 216 231 - T 22-04-2016 IPR019826 Carboxylesterase type B, active site TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 32 46 6.9E-8 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 46 64 6.9E-8 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 PANTHER PTHR30363 10 259 8.0E-63 T 22-04-2016 TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 Pfam PF08220 DeoR-like helix-turn-helix domain 14 65 8.6E-15 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 SUPERFAMILY SSF100950 81 236 8.12E-22 T 22-04-2016 TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 SUPERFAMILY SSF46785 12 68 1.93E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 SMART SM00420 14 66 1.3E-11 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 Gene3D G3DSA:1.10.10.10 13 62 1.9E-10 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 PANTHER PTHR30363:SF1 10 259 8.0E-63 T 22-04-2016 TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 ProSitePatterns PS00894 DeoR-type HTH domain signature. 14 48 - T 22-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 Pfam PF00455 DeoR C terminal sensor domain 81 237 1.5E-40 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 Gene3D G3DSA:3.40.50.1360 83 221 2.3E-10 T 22-04-2016 TOLA_RS09065 7d0db6667520fb4c4c6cc43105bc5ac5 260 SMART SM01134 79 240 5.8E-50 T 22-04-2016 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 SMART SM00873 212 386 1.5E-91 T 22-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 SUPERFAMILY SSF46955 405 476 3.11E-21 T 22-04-2016 IPR009061 Putative DNA-binding domain TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 SMART SM00874 404 472 1.0E-29 T 22-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 795 2.8E-275 T 22-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 Gene3D G3DSA:2.40.50.140 42 154 2.7E-45 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 Pfam PF03484 tRNA synthetase B5 domain 406 472 1.0E-19 T 22-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 SMART SM00896 702 795 9.1E-43 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 PANTHER PTHR10947:SF0 2 795 0.0 T 22-04-2016 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 PANTHER PTHR10947 2 795 0.0 T 22-04-2016 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 Gene3D G3DSA:3.30.70.380 704 795 6.6E-30 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 SUPERFAMILY SSF56037 196 393 5.49E-72 T 22-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 789 46.742 T 22-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 Pfam PF01588 Putative tRNA binding domain 45 145 1.7E-26 T 22-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 SUPERFAMILY SSF55681 468 691 6.46E-54 T 22-04-2016 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 Gene3D G3DSA:3.50.40.10 198 393 4.8E-81 T 22-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 Pfam PF03483 B3/4 domain 213 386 5.7E-68 T 22-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 Pfam PF03147 Ferredoxin-fold anticodon binding domain 702 795 2.4E-27 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 SUPERFAMILY SSF50249 35 197 8.81E-50 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 Gene3D G3DSA:3.30.56.20 404 476 5.7E-28 T 22-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 Gene3D G3DSA:3.30.930.10 491 692 3.3E-67 T 22-04-2016 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 Gene3D G3DSA:3.30.56.10 155 183 7.2E-23 T 22-04-2016 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 Gene3D G3DSA:3.30.56.10 1 38 7.2E-23 T 22-04-2016 TOLA_RS08770 0a5262d7dae1807fbe6fbe72218b9f4f 796 SUPERFAMILY SSF54991 697 795 1.44E-30 T 22-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 SUPERFAMILY SSF52343 306 439 4.58E-22 T 22-04-2016 TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 Gene3D G3DSA:3.40.50.80 309 437 6.2E-20 T 22-04-2016 TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 PANTHER PTHR11972 36 443 2.4E-44 T 22-04-2016 TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 SUPERFAMILY SSF63380 239 317 2.87E-16 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 PANTHER PTHR11972:SF23 36 443 2.4E-44 T 22-04-2016 TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 Gene3D G3DSA:2.40.30.10 243 308 3.8E-12 T 22-04-2016 TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 PRINTS PR00410 Phenol hydroxylase reductase family signature 312 321 2.3E-7 T 22-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 PRINTS PR00410 Phenol hydroxylase reductase family signature 409 417 2.3E-7 T 22-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 PRINTS PR00410 Phenol hydroxylase reductase family signature 253 265 2.3E-7 T 22-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 PRINTS PR00410 Phenol hydroxylase reductase family signature 327 346 2.3E-7 T 22-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 Pfam PF01794 Ferric reductase like transmembrane component 45 179 3.2E-15 T 22-04-2016 IPR013130 Ferric reductase transmembrane component-like domain TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 Pfam PF00175 Oxidoreductase NAD-binding domain 329 422 2.9E-4 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TOLA_RS06740 f010f8a84bba1c6d6efcce8696a2bbbb 444 Pfam PF00970 Oxidoreductase FAD-binding domain 252 318 1.7E-7 T 22-04-2016 IPR008333 Oxidoreductase, FAD-binding domain TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 SMART SM00086 142 184 7.6E-5 T 22-04-2016 IPR001610 PAC motif TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 Pfam PF00990 Diguanylate cyclase, GGDEF domain 195 353 1.1E-49 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 Gene3D G3DSA:1.20.120.50 373 497 5.0E-23 T 22-04-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 375 498 2.6E-22 T 22-04-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 SUPERFAMILY SSF55785 67 186 3.22E-19 T 22-04-2016 IPR000014 PAS domain TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 ProSitePatterns PS00550 Hemerythrin family signature. 429 452 - T 22-04-2016 IPR016131 Haemerythrin, iron-binding site GO:0046872 TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 PANTHER PTHR10799 74 355 1.4E-43 T 22-04-2016 TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 SUPERFAMILY SSF55073 200 359 3.61E-52 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 58 189 6.3E-20 T 22-04-2016 IPR000014 PAS domain TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 PANTHER PTHR10799:SF774 74 355 1.4E-43 T 22-04-2016 TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 SMART SM00091 62 129 6.5E-6 T 22-04-2016 IPR000014 PAS domain TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 Gene3D G3DSA:3.30.70.270 197 361 1.0E-57 T 22-04-2016 TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 Gene3D G3DSA:3.30.450.20 50 182 1.7E-20 T 22-04-2016 TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 SUPERFAMILY SSF47188 373 498 3.27E-19 T 22-04-2016 IPR012827 Haemerythrin, metal-binding domain GO:0046872 TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 SMART SM00267 184 357 4.6E-67 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 Pfam PF13426 PAS domain 81 183 5.7E-9 T 22-04-2016 IPR000014 PAS domain TOLA_RS06745 d63866736d0e927d25a5a554411a7406 504 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 193 356 8.2E-47 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS06330 407004b1ae1ff9a3c491b0251bb0754f 110 SUPERFAMILY SSF55604 6 80 1.27E-19 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS06330 407004b1ae1ff9a3c491b0251bb0754f 110 Gene3D G3DSA:3.30.1360.60 2 81 1.8E-23 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS06330 407004b1ae1ff9a3c491b0251bb0754f 110 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS06330 407004b1ae1ff9a3c491b0251bb0754f 110 PANTHER PTHR30175 1 104 1.1E-28 T 22-04-2016 TOLA_RS06330 407004b1ae1ff9a3c491b0251bb0754f 110 PANTHER PTHR30175:SF7 1 104 1.1E-28 T 22-04-2016 TOLA_RS06330 407004b1ae1ff9a3c491b0251bb0754f 110 Pfam PF00367 phosphotransferase system, EIIB 8 41 5.7E-14 T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS03540 79f088b0b8f34476160977791e2c407d 112 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 112 1.0E-50 T 22-04-2016 IPR004624 PhnA protein TOLA_RS03540 79f088b0b8f34476160977791e2c407d 112 Gene3D G3DSA:2.20.25.10 1 41 1.9E-21 T 22-04-2016 TOLA_RS03540 79f088b0b8f34476160977791e2c407d 112 SUPERFAMILY SSF82057 40 112 9.61E-30 T 22-04-2016 TOLA_RS03540 79f088b0b8f34476160977791e2c407d 112 Gene3D G3DSA:2.30.30.40 44 112 2.3E-37 T 22-04-2016 TOLA_RS03540 79f088b0b8f34476160977791e2c407d 112 Pfam PF08274 PhnA Zinc-Ribbon 4 32 9.2E-16 T 22-04-2016 IPR013987 PhnA protein, N-terminal TOLA_RS03540 79f088b0b8f34476160977791e2c407d 112 Pfam PF03831 PhnA domain 46 112 1.9E-34 T 22-04-2016 IPR013988 PhnA protein, C-terminal TOLA_RS03540 79f088b0b8f34476160977791e2c407d 112 SUPERFAMILY SSF57783 3 37 1.45E-14 T 22-04-2016 TOLA_RS03540 79f088b0b8f34476160977791e2c407d 112 PANTHER PTHR30305 2 112 5.5E-79 T 22-04-2016 TOLA_RS04705 e1a1b4eab8039231fdb3811d4d9f75d2 345 SUPERFAMILY SSF56042 171 339 7.18E-63 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain TOLA_RS04705 e1a1b4eab8039231fdb3811d4d9f75d2 345 Gene3D G3DSA:3.30.1330.10 22 170 3.5E-62 T 22-04-2016 IPR016188 PurM-like, N-terminal domain TOLA_RS04705 e1a1b4eab8039231fdb3811d4d9f75d2 345 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 7 334 1.2E-148 T 22-04-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 TOLA_RS04705 e1a1b4eab8039231fdb3811d4d9f75d2 345 SUPERFAMILY SSF55326 7 170 9.12E-52 T 22-04-2016 TOLA_RS04705 e1a1b4eab8039231fdb3811d4d9f75d2 345 Pfam PF00586 AIR synthase related protein, N-terminal domain 65 164 6.8E-15 T 22-04-2016 IPR016188 PurM-like, N-terminal domain TOLA_RS04705 e1a1b4eab8039231fdb3811d4d9f75d2 345 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 344 47.064 T 22-04-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 TOLA_RS04705 e1a1b4eab8039231fdb3811d4d9f75d2 345 PANTHER PTHR10520 4 345 6.5E-222 T 22-04-2016 TOLA_RS04705 e1a1b4eab8039231fdb3811d4d9f75d2 345 Pfam PF02769 AIR synthase related protein, C-terminal domain 177 336 5.8E-37 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain TOLA_RS04705 e1a1b4eab8039231fdb3811d4d9f75d2 345 Gene3D G3DSA:3.90.650.10 171 342 9.7E-69 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain TOLA_RS14915 c585b16edffa418165cc4cabb0def0ed 373 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 56 269 1.5E-28 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TOLA_RS14915 c585b16edffa418165cc4cabb0def0ed 373 Gene3D G3DSA:2.40.50.100 163 194 2.4E-13 T 22-04-2016 TOLA_RS14915 c585b16edffa418165cc4cabb0def0ed 373 Gene3D G3DSA:2.40.50.100 71 102 2.4E-13 T 22-04-2016 TOLA_RS14915 c585b16edffa418165cc4cabb0def0ed 373 Pfam PF00529 HlyD membrane-fusion protein of T1SS 16 344 2.2E-7 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 TOLA_RS14915 c585b16edffa418165cc4cabb0def0ed 373 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 358 3.6E-72 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 TOLA_RS14915 c585b16edffa418165cc4cabb0def0ed 373 PANTHER PTHR30469 1 369 5.3E-123 T 22-04-2016 TOLA_RS14915 c585b16edffa418165cc4cabb0def0ed 373 PANTHER PTHR30469:SF11 1 369 5.3E-123 T 22-04-2016 TOLA_RS14915 c585b16edffa418165cc4cabb0def0ed 373 SUPERFAMILY SSF111369 57 273 7.45E-39 T 22-04-2016 TOLA_RS14500 26985b1650e87d8b0f75ffe775719259 367 PANTHER PTHR30474 1 366 3.0E-165 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 TOLA_RS14500 26985b1650e87d8b0f75ffe775719259 367 Pfam PF01098 Cell cycle protein 21 364 2.5E-115 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 TOLA_RS14500 26985b1650e87d8b0f75ffe775719259 367 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 321 345 - T 22-04-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 TOLA_RS14500 26985b1650e87d8b0f75ffe775719259 367 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 17 364 9.0E-136 T 22-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 TOLA_RS14500 26985b1650e87d8b0f75ffe775719259 367 PANTHER PTHR30474:SF1 1 366 3.0E-165 T 22-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 TOLA_RS07645 95b64a90f7dcf31f86df51a56bfc5fbd 297 SUPERFAMILY SSF46785 2 79 2.88E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07645 95b64a90f7dcf31f86df51a56bfc5fbd 297 SUPERFAMILY SSF53850 91 294 5.97E-37 T 22-04-2016 TOLA_RS07645 95b64a90f7dcf31f86df51a56bfc5fbd 297 Gene3D G3DSA:1.10.10.10 1 82 5.2E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07645 95b64a90f7dcf31f86df51a56bfc5fbd 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.6E-9 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07645 95b64a90f7dcf31f86df51a56bfc5fbd 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.6E-9 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07645 95b64a90f7dcf31f86df51a56bfc5fbd 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.6E-9 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07645 95b64a90f7dcf31f86df51a56bfc5fbd 297 Pfam PF03466 LysR substrate binding domain 91 294 1.3E-31 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS07645 95b64a90f7dcf31f86df51a56bfc5fbd 297 PANTHER PTHR30537:SF1 1 296 2.5E-164 T 22-04-2016 TOLA_RS07645 95b64a90f7dcf31f86df51a56bfc5fbd 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 5.5E-21 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07645 95b64a90f7dcf31f86df51a56bfc5fbd 297 Gene3D G3DSA:3.40.190.10 180 263 3.8E-7 T 22-04-2016 TOLA_RS07645 95b64a90f7dcf31f86df51a56bfc5fbd 297 Gene3D G3DSA:3.40.190.10 94 179 4.6E-13 T 22-04-2016 TOLA_RS07645 95b64a90f7dcf31f86df51a56bfc5fbd 297 PANTHER PTHR30537 1 296 2.5E-164 T 22-04-2016 TOLA_RS05840 ac64738e9dae66999b158d750042c595 317 Pfam PF06067 Domain of unknown function (DUF932) 75 297 4.2E-77 T 22-04-2016 IPR026325 Protein of unknown function DUF932 TOLA_RS05840 ac64738e9dae66999b158d750042c595 317 TIGRFAM TIGR03299 LGT_TIGR03299: phage/plasmid-like protein TIGR03299 6 313 4.4E-115 T 22-04-2016 IPR017686 Phage/plasmid-like protein TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 Gene3D G3DSA:1.20.120.530 97 229 2.5E-27 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.5E-8 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.5E-8 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 PANTHER PTHR11751:SF421 1 79 6.3E-45 T 22-04-2016 TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 PANTHER PTHR11751:SF421 95 113 6.3E-45 T 22-04-2016 TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 SMART SM00895 97 221 9.4E-20 T 22-04-2016 IPR011711 GntR, C-terminal TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 SMART SM00345 13 72 1.1E-22 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 PANTHER PTHR11751 1 79 6.3E-45 T 22-04-2016 TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 PANTHER PTHR11751 95 113 6.3E-45 T 22-04-2016 TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 72 5.2E-22 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 Gene3D G3DSA:1.10.10.10 7 74 1.1E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 SUPERFAMILY SSF46785 5 76 3.96E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 SUPERFAMILY SSF48008 95 228 7.85E-25 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal TOLA_RS15520 00c2bf728493d8edb645816dbad4d0c9 254 Pfam PF07729 FCD domain 97 220 4.7E-21 T 22-04-2016 IPR011711 GntR, C-terminal TOLA_RS02410 83a30a5a31b497f9831f64411e381d08 240 Gene3D G3DSA:3.40.1130.10 62 182 4.3E-14 T 22-04-2016 TOLA_RS02410 83a30a5a31b497f9831f64411e381d08 240 PANTHER PTHR10434 1 236 7.2E-107 T 22-04-2016 TOLA_RS02410 83a30a5a31b497f9831f64411e381d08 240 SMART SM00563 67 182 5.6E-36 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TOLA_RS02410 83a30a5a31b497f9831f64411e381d08 240 PANTHER PTHR10434:SF20 1 236 7.2E-107 T 22-04-2016 TOLA_RS02410 83a30a5a31b497f9831f64411e381d08 240 SUPERFAMILY SSF69593 6 236 2.88E-42 T 22-04-2016 TOLA_RS02410 83a30a5a31b497f9831f64411e381d08 240 TIGRFAM TIGR00530 AGP_acyltrn: 1-acylglycerol-3-phosphate O-acyltransferases 50 179 1.1E-39 T 22-04-2016 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase GO:0003841|GO:0008654|GO:0016020 KEGG: 00561+2.3.1.51|KEGG: 00564+2.3.1.51|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7417|MetaCyc: PWY-7587|MetaCyc: PWY-7589|Reactome: REACT_22258|UniPathway: UPA00557 TOLA_RS02410 83a30a5a31b497f9831f64411e381d08 240 Pfam PF01553 Acyltransferase 59 180 3.1E-27 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TOLA_RS08395 e18142985c5cf4b225217720feb39892 329 Gene3D G3DSA:3.40.50.720 1 296 2.2E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS08395 e18142985c5cf4b225217720feb39892 329 PANTHER PTHR10366 2 325 3.7E-44 T 22-04-2016 TOLA_RS08395 e18142985c5cf4b225217720feb39892 329 SUPERFAMILY SSF51735 1 302 3.06E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS08395 e18142985c5cf4b225217720feb39892 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 216 2.0E-19 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 TOLA_RS04090 b3dd7fbbfc1d0fea3e693a36e9f80ae2 378 PANTHER PTHR18895:SF6 83 376 1.9E-135 T 22-04-2016 TOLA_RS04090 b3dd7fbbfc1d0fea3e693a36e9f80ae2 378 Gene3D G3DSA:3.40.50.150 200 360 5.9E-23 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04090 b3dd7fbbfc1d0fea3e693a36e9f80ae2 378 PIRSF PIRSF037565 1 378 7.1E-157 T 22-04-2016 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS04090 b3dd7fbbfc1d0fea3e693a36e9f80ae2 378 Pfam PF05175 Methyltransferase small domain 203 374 1.8E-52 T 22-04-2016 IPR007848 Methyltransferase small domain GO:0008168 TOLA_RS04090 b3dd7fbbfc1d0fea3e693a36e9f80ae2 378 SUPERFAMILY SSF53335 200 348 1.46E-26 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04090 b3dd7fbbfc1d0fea3e693a36e9f80ae2 378 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 1 377 49.129 T 22-04-2016 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS04090 b3dd7fbbfc1d0fea3e693a36e9f80ae2 378 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 306 312 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TOLA_RS04090 b3dd7fbbfc1d0fea3e693a36e9f80ae2 378 PANTHER PTHR18895 83 376 1.9E-135 T 22-04-2016 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 SUPERFAMILY SSF88723 5 170 7.36E-54 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 Pfam PF01612 3'-5' exonuclease 311 498 2.4E-39 T 22-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 171 271 2.5E-26 T 22-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 PANTHER PTHR10133:SF27 2 909 0.0 T 22-04-2016 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 Gene3D G3DSA:1.10.150.20 187 253 1.5E-20 T 22-04-2016 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 Gene3D G3DSA:3.30.420.10 310 523 5.3E-86 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 SMART SM00475 4 268 3.3E-114 T 22-04-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 SMART SM00279 173 208 1.4E-10 T 22-04-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 Gene3D G3DSA:1.10.150.20 693 799 4.6E-37 T 22-04-2016 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 SUPERFAMILY SSF47807 171 292 1.3E-24 T 22-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 Gene3D G3DSA:3.30.70.370 645 692 1.4E-68 T 22-04-2016 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 Gene3D G3DSA:3.30.70.370 800 910 1.4E-68 T 22-04-2016 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 7 170 5.7E-52 T 22-04-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 SUPERFAMILY SSF56672 504 910 4.56E-159 T 22-04-2016 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 Gene3D G3DSA:3.40.50.1010 6 186 1.5E-68 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 SMART SM00474 311 498 5.0E-39 T 22-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 PANTHER PTHR10133 2 909 0.0 T 22-04-2016 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 Gene3D G3DSA:1.20.1060.10 525 644 2.9E-37 T 22-04-2016 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 Pfam PF00476 DNA polymerase family A 533 907 3.7E-157 T 22-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 SMART SM00482 667 874 1.9E-119 T 22-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 TIGRFAM TIGR00593 pola: DNA polymerase I 7 910 8.0E-285 T 22-04-2016 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 PRINTS PR00868 DNA-polymerase family A (pol I) signature 857 870 7.4E-80 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 PRINTS PR00868 DNA-polymerase family A (pol I) signature 826 842 7.4E-80 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 PRINTS PR00868 DNA-polymerase family A (pol I) signature 794 805 7.4E-80 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 PRINTS PR00868 DNA-polymerase family A (pol I) signature 735 760 7.4E-80 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 PRINTS PR00868 DNA-polymerase family A (pol I) signature 711 724 7.4E-80 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 PRINTS PR00868 DNA-polymerase family A (pol I) signature 636 658 7.4E-80 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 PRINTS PR00868 DNA-polymerase family A (pol I) signature 681 704 7.4E-80 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 PRINTS PR00868 DNA-polymerase family A (pol I) signature 772 783 7.4E-80 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 PRINTS PR00868 DNA-polymerase family A (pol I) signature 659 674 7.4E-80 T 22-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 ProSitePatterns PS00447 DNA polymerase family A signature. 735 754 - T 22-04-2016 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS01770 0bc70f7995cdf24261db1ed00ef63fa2 910 SUPERFAMILY SSF53098 314 499 9.28E-57 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 Gene3D G3DSA:3.30.930.10 159 507 2.2E-120 T 22-04-2016 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 PANTHER PTHR22594 5 512 8.4E-275 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 Pfam PF00152 tRNA synthetases class II (D, K and N) 165 508 8.5E-82 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 Pfam PF01336 OB-fold nucleic acid binding domain 70 148 1.5E-16 T 22-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 SUPERFAMILY SSF50249 16 157 4.07E-46 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 Gene3D G3DSA:2.40.50.140 18 156 3.4E-49 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 PRINTS PR00982 Lysyl-tRNA synthetase signature 246 259 2.4E-39 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 PRINTS PR00982 Lysyl-tRNA synthetase signature 201 211 2.4E-39 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 PRINTS PR00982 Lysyl-tRNA synthetase signature 264 281 2.4E-39 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 PRINTS PR00982 Lysyl-tRNA synthetase signature 393 409 2.4E-39 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 PRINTS PR00982 Lysyl-tRNA synthetase signature 217 233 2.4E-39 T 22-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 SUPERFAMILY SSF55681 164 509 3.19E-121 T 22-04-2016 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 PANTHER PTHR22594:SF4 5 512 8.4E-275 T 22-04-2016 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 23 513 44.703 T 22-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 17 511 5.5E-222 T 22-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 TOLA_RS05020 eeb1aa19f5b53b6dcf9b2e9d059c4f99 513 PIRSF PIRSF039101 1 513 7.4E-207 T 22-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 TOLA_RS08130 2f79e5a5c09416d7758cd54403791fb6 86 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 16 74 5.9E-10 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS08130 2f79e5a5c09416d7758cd54403791fb6 86 Gene3D G3DSA:1.10.260.40 13 77 1.0E-11 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS08130 2f79e5a5c09416d7758cd54403791fb6 86 SUPERFAMILY SSF47413 13 75 6.19E-9 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 Gene3D G3DSA:3.40.50.300 5 193 9.1E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 SUPERFAMILY SSF52540 11 206 1.57E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 SUPERFAMILY SSF54814 182 297 2.94E-43 T 22-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 79 97 2.7E-6 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 2.7E-6 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 280 4.9E-112 T 22-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 Pfam PF07650 KH domain 209 285 4.4E-19 T 22-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 PANTHER PTHR11649:SF3 3 300 1.4E-129 T 22-04-2016 TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 Hamap MF_00367 GTPase Era [era]. 6 297 36.765 T 22-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 Pfam PF01926 50S ribosome-binding GTPase 11 125 3.4E-24 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 Gene3D G3DSA:3.30.300.20 194 294 3.8E-41 T 22-04-2016 IPR015946 K homology domain-like, alpha/beta TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 PANTHER PTHR11649 3 300 1.4E-129 T 22-04-2016 TOLA_RS04365 d613750f30c18c4ec0bd4ec4301228c6 300 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 169 1.4E-36 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS03455 6ec36fd1e5237fe72cd71cad83b6c67d 97 Gene3D G3DSA:2.40.10.220 4 93 1.4E-8 T 22-04-2016 TOLA_RS03455 6ec36fd1e5237fe72cd71cad83b6c67d 97 SUPERFAMILY SSF141371 1 95 6.87E-13 T 22-04-2016 TOLA_RS03455 6ec36fd1e5237fe72cd71cad83b6c67d 97 Pfam PF07238 PilZ domain 7 95 9.0E-11 T 22-04-2016 IPR009875 PilZ domain GO:0035438 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 PANTHER PTHR11946:SF5 879 943 0.0 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 PANTHER PTHR11946:SF5 608 859 0.0 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 PANTHER PTHR11946:SF5 1 570 0.0 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 SUPERFAMILY SSF47323 642 898 1.87E-69 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 TIGRFAM TIGR00422 valS: valine--tRNA ligase 1 930 0.0 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 SUPERFAMILY SSF52374 364 571 8.19E-138 T 22-04-2016 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 SUPERFAMILY SSF52374 1 192 8.19E-138 T 22-04-2016 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 SUPERFAMILY SSF52374 609 641 8.19E-138 T 22-04-2016 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 SUPERFAMILY SSF46589 883 947 2.2E-17 T 22-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 883 946 1.8E-17 T 22-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 Gene3D G3DSA:1.10.287.380 877 943 2.9E-7 T 22-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 PANTHER PTHR11946 879 943 0.0 T 22-04-2016 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 PANTHER PTHR11946 608 859 0.0 T 22-04-2016 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 PANTHER PTHR11946 1 570 0.0 T 22-04-2016 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 631 7.1E-221 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 Hamap MF_02004 Valine--tRNA ligase [valS]. 1 948 16.059 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 PRINTS PR00986 Valyl-tRNA synthetase signature 469 490 1.3E-35 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 PRINTS PR00986 Valyl-tRNA synthetase signature 369 382 1.3E-35 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 PRINTS PR00986 Valyl-tRNA synthetase signature 236 253 1.3E-35 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 PRINTS PR00986 Valyl-tRNA synthetase signature 35 46 1.3E-35 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 PRINTS PR00986 Valyl-tRNA synthetase signature 500 518 1.3E-35 T 22-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 SUPERFAMILY SSF50677 190 363 1.09E-56 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 Gene3D G3DSA:3.90.740.10 194 360 4.9E-48 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 Gene3D G3DSA:3.40.50.620 364 571 1.2E-143 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 Gene3D G3DSA:3.40.50.620 3 193 1.2E-143 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 Gene3D G3DSA:3.40.50.620 609 630 1.2E-143 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 Gene3D G3DSA:1.10.730.10 631 816 2.1E-63 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS02855 921810a818fc2184ee7cf526ded7d695 950 Pfam PF08264 Anticodon-binding domain of tRNA 674 825 4.4E-41 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 TOLA_RS10060 9f2db42206fc0927ba9893a71dca4797 219 PANTHER PTHR11749 1 217 2.6E-95 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS10060 9f2db42206fc0927ba9893a71dca4797 219 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS10060 9f2db42206fc0927ba9893a71dca4797 219 SUPERFAMILY SSF51366 1 216 8.63E-63 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TOLA_RS10060 9f2db42206fc0927ba9893a71dca4797 219 PIRSF PIRSF001461 1 219 1.3E-78 T 22-04-2016 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS10060 9f2db42206fc0927ba9893a71dca4797 219 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 198 1.2E-73 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS10060 9f2db42206fc0927ba9893a71dca4797 219 Gene3D G3DSA:3.20.20.70 2 216 2.0E-78 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS10060 9f2db42206fc0927ba9893a71dca4797 219 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 133 155 - T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS10060 9f2db42206fc0927ba9893a71dca4797 219 PANTHER PTHR11749:SF3 1 217 2.6E-95 T 22-04-2016 TOLA_RS10060 9f2db42206fc0927ba9893a71dca4797 219 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 215 2.2E-77 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS15615 3565b7c4ad18452a8895f36acc653f3d 371 PANTHER PTHR10804 18 370 1.7E-35 T 22-04-2016 TOLA_RS15615 3565b7c4ad18452a8895f36acc653f3d 371 PANTHER PTHR10804:SF110 18 370 1.7E-35 T 22-04-2016 TOLA_RS15615 3565b7c4ad18452a8895f36acc653f3d 371 SUPERFAMILY SSF55920 141 370 7.72E-47 T 22-04-2016 IPR000994 Peptidase M24, structural domain TOLA_RS15615 3565b7c4ad18452a8895f36acc653f3d 371 Pfam PF00557 Metallopeptidase family M24 150 359 3.5E-32 T 22-04-2016 IPR000994 Peptidase M24, structural domain TOLA_RS15615 3565b7c4ad18452a8895f36acc653f3d 371 Pfam PF01321 Creatinase/Prolidase N-terminal domain 11 142 1.8E-17 T 22-04-2016 IPR000587 Creatinase, N-terminal GO:0016787 TOLA_RS15615 3565b7c4ad18452a8895f36acc653f3d 371 SUPERFAMILY SSF53092 4 141 2.27E-21 T 22-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal TOLA_RS15615 3565b7c4ad18452a8895f36acc653f3d 371 Gene3D G3DSA:3.90.230.10 141 370 6.0E-45 T 22-04-2016 IPR000994 Peptidase M24, structural domain TOLA_RS15615 3565b7c4ad18452a8895f36acc653f3d 371 Gene3D G3DSA:3.40.350.10 7 140 2.3E-20 T 22-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TOLA_RS11710 f691d31409be3fcb5db13f6125fe3521 304 PANTHER PTHR30352:SF4 1 54 1.4E-90 T 22-04-2016 TOLA_RS11710 f691d31409be3fcb5db13f6125fe3521 304 PANTHER PTHR30352:SF4 101 304 1.4E-90 T 22-04-2016 TOLA_RS11710 f691d31409be3fcb5db13f6125fe3521 304 Gene3D G3DSA:3.80.30.10 123 302 4.0E-48 T 22-04-2016 TOLA_RS11710 f691d31409be3fcb5db13f6125fe3521 304 Pfam PF04055 Radical SAM superfamily 19 230 3.4E-25 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS11710 f691d31409be3fcb5db13f6125fe3521 304 PANTHER PTHR30352 1 54 1.4E-90 T 22-04-2016 TOLA_RS11710 f691d31409be3fcb5db13f6125fe3521 304 PANTHER PTHR30352 101 304 1.4E-90 T 22-04-2016 TOLA_RS11710 f691d31409be3fcb5db13f6125fe3521 304 SUPERFAMILY SSF102114 124 269 1.37E-14 T 22-04-2016 TOLA_RS11710 f691d31409be3fcb5db13f6125fe3521 304 ProSitePatterns PS01087 Radical activating enzymes signature. 13 34 - T 22-04-2016 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 TOLA_RS11710 f691d31409be3fcb5db13f6125fe3521 304 Gene3D G3DSA:3.30.70.20 45 103 2.7E-4 T 22-04-2016 TOLA_RS11710 f691d31409be3fcb5db13f6125fe3521 304 PIRSF PIRSF000371 1 304 5.2E-85 T 22-04-2016 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 TOLA_RS11710 f691d31409be3fcb5db13f6125fe3521 304 Pfam PF13353 4Fe-4S single cluster domain 12 154 3.7E-11 T 22-04-2016 TOLA_RS11710 f691d31409be3fcb5db13f6125fe3521 304 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 2 295 3.7E-94 T 22-04-2016 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 TOLA_RS15840 7efb814468715e44a4595862077c9a9d 430 Pfam PF07690 Major Facilitator Superfamily 24 343 8.2E-19 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS15840 7efb814468715e44a4595862077c9a9d 430 SUPERFAMILY SSF103473 11 414 3.27E-45 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS15840 7efb814468715e44a4595862077c9a9d 430 Gene3D G3DSA:1.20.1250.20 15 202 2.5E-17 T 22-04-2016 TOLA_RS15840 7efb814468715e44a4595862077c9a9d 430 Gene3D G3DSA:1.20.1250.20 224 410 1.2E-19 T 22-04-2016 TOLA_RS06245 7586beac3638102858ebc1a54d33fa96 437 Pfam PF01420 Type I restriction modification DNA specificity domain 30 194 2.6E-16 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TOLA_RS06245 7586beac3638102858ebc1a54d33fa96 437 Pfam PF01420 Type I restriction modification DNA specificity domain 243 410 1.5E-16 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TOLA_RS06245 7586beac3638102858ebc1a54d33fa96 437 PANTHER PTHR30408:SF7 58 269 4.5E-27 T 22-04-2016 TOLA_RS06245 7586beac3638102858ebc1a54d33fa96 437 SUPERFAMILY SSF116734 229 428 6.7E-33 T 22-04-2016 TOLA_RS06245 7586beac3638102858ebc1a54d33fa96 437 PANTHER PTHR30408 58 269 4.5E-27 T 22-04-2016 TOLA_RS06245 7586beac3638102858ebc1a54d33fa96 437 SUPERFAMILY SSF116734 21 209 3.92E-37 T 22-04-2016 TOLA_RS07860 60e00ba73a0e2c9d8d2fe69e1a8cb330 179 Pfam PF07126 Cell-division protein ZapC 3 170 9.0E-55 T 22-04-2016 IPR009809 Cell division protein ZapC TOLA_RS07860 60e00ba73a0e2c9d8d2fe69e1a8cb330 179 PIRSF PIRSF010252 1 179 4.1E-47 T 22-04-2016 IPR009809 Cell division protein ZapC TOLA_RS07860 60e00ba73a0e2c9d8d2fe69e1a8cb330 179 Hamap MF_00906 Cell division protein ZapC [zapC]. 2 178 36.731 T 22-04-2016 IPR009809 Cell division protein ZapC TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 PANTHER PTHR11938 23 424 7.6E-72 T 22-04-2016 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 Gene3D G3DSA:3.50.50.60 348 433 4.0E-11 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 35 111 6.5E-17 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 489 500 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 520 531 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 347 363 2.8E-20 T 22-04-2016 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 375 397 2.8E-20 T 22-04-2016 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 128 147 2.8E-20 T 22-04-2016 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 274 2.8E-20 T 22-04-2016 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 149 9.6E-13 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 385 403 9.6E-13 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 252 276 9.6E-13 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 SUPERFAMILY SSF51971 125 356 1.12E-56 T 22-04-2016 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 Gene3D G3DSA:3.30.70.20 486 541 7.4E-14 T 22-04-2016 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 Gene3D G3DSA:3.50.50.60 219 347 7.2E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 SUPERFAMILY SSF46548 34 135 6.28E-22 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 PANTHER PTHR11938:SF108 23 424 7.6E-72 T 22-04-2016 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 Gene3D G3DSA:3.50.50.60 127 218 1.1E-20 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 126 410 1.9E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 Gene3D G3DSA:1.10.1060.10 35 126 8.9E-26 T 22-04-2016 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 SUPERFAMILY SSF46548 436 537 3.03E-16 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 TOLA_RS10145 755f043d77e1c07569df764c1d2aa184 544 Pfam PF00037 4Fe-4S binding domain 514 536 3.5E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 2 408 63.201 T 22-04-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 45 115 4.1E-11 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 Gene3D G3DSA:3.40.50.80 271 407 1.1E-41 T 22-04-2016 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 SUPERFAMILY SSF63380 106 270 3.57E-35 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 PIRSF PIRSF000044 1 408 2.9E-217 T 22-04-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 Gene3D G3DSA:3.10.20.30 37 124 2.0E-21 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 Pfam PF00970 Oxidoreductase FAD-binding domain 205 267 3.4E-10 T 22-04-2016 IPR008333 Oxidoreductase, FAD-binding domain TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 Gene3D G3DSA:2.40.30.10 125 265 8.8E-60 T 22-04-2016 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 SUPERFAMILY SSF54292 39 125 3.14E-23 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 Pfam PF00175 Oxidoreductase NAD-binding domain 278 387 9.5E-17 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 4 408 8.4E-220 T 22-04-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 SUPERFAMILY SSF52343 258 403 1.7E-37 T 22-04-2016 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 PANTHER PTHR19370 206 408 1.3E-143 T 22-04-2016 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 PANTHER PTHR19370 62 177 1.3E-143 T 22-04-2016 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 PANTHER PTHR19370:SF32 206 408 1.3E-143 T 22-04-2016 TOLA_RS15390 c97b9dec7ccc2d554a7caab3154836ea 408 PANTHER PTHR19370:SF32 62 177 1.3E-143 T 22-04-2016 TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 PIRSF PIRSF500134 1 343 8.3E-123 T 22-04-2016 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|UniPathway: UPA00038 TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 Gene3D G3DSA:3.40.50.720 285 388 1.2E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 SMART SM00984 300 387 5.9E-12 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 Gene3D G3DSA:1.10.1040.10 198 284 2.0E-35 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 SUPERFAMILY SSF48179 191 287 8.05E-31 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 192 281 1.6E-27 T 22-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 SUPERFAMILY SSF52413 283 388 3.79E-27 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 380 1.2E-104 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 Gene3D G3DSA:3.40.50.720 1 197 2.2E-68 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 301 374 1.1E-7 T 22-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 PANTHER PTHR11374 1 368 6.9E-238 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 SUPERFAMILY SSF51735 1 194 4.69E-49 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 PANTHER PTHR11374:SF17 1 368 6.9E-238 T 22-04-2016 TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 PIRSF PIRSF000124 1 388 1.0E-136 T 22-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 TOLA_RS14570 9b2adf4d0912b896ae61ba243ecde136 388 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 170 4.0E-32 T 22-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 PIRSF PIRSF039144 1 112 3.2E-53 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 PANTHER PTHR30115:SF15 1 112 5.0E-70 T 22-04-2016 TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 PRINTS PR00340 P-II protein signature 83 103 8.6E-41 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 PRINTS PR00340 P-II protein signature 2 17 8.6E-41 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 PRINTS PR00340 P-II protein signature 52 75 8.6E-41 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 PRINTS PR00340 P-II protein signature 23 41 8.6E-41 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 Gene3D G3DSA:3.30.70.120 1 112 8.0E-49 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 22-04-2016 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 PANTHER PTHR30115 1 112 5.0E-70 T 22-04-2016 TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 SUPERFAMILY SSF54913 1 112 1.56E-43 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 22-04-2016 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 SMART SM00938 4 105 6.7E-65 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS13025 2ec0a9b3c8a3c2da87abd22f6b7ea698 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.9E-42 T 22-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 SUPERFAMILY SSF81653 236 330 1.44E-22 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 PRINTS PR00941 Cadmium-transporting ATPase signature 296 312 1.2E-8 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 PRINTS PR00941 Cadmium-transporting ATPase signature 315 329 1.2E-8 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 PRINTS PR00941 Cadmium-transporting ATPase signature 214 234 1.2E-8 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 PRINTS PR00941 Cadmium-transporting ATPase signature 160 172 1.2E-8 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 179 730 1.0E-176 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 SUPERFAMILY SSF56784 429 449 3.51E-49 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 SUPERFAMILY SSF56784 486 728 3.51E-49 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 202 706 3.7E-78 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 PANTHER PTHR24093 115 733 5.0E-220 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 SUPERFAMILY SSF81665 175 233 1.57E-17 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 SUPERFAMILY SSF81665 331 424 1.57E-17 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 SUPERFAMILY SSF81665 677 708 1.57E-17 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 PANTHER PTHR24093:SF317 115 733 5.0E-220 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 Pfam PF00702 haloacid dehalogenase-like hydrolase 429 640 1.9E-34 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 Gene3D G3DSA:3.40.50.1000 406 444 1.1E-42 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 Gene3D G3DSA:3.40.50.1000 556 696 1.1E-42 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 Gene3D G3DSA:2.70.150.10 182 331 1.2E-25 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 161 730 8.0E-126 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 Pfam PF00122 E1-E2 ATPase 200 422 1.1E-64 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 280 294 4.3E-22 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 651 663 4.3E-22 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 627 646 4.3E-22 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 575 585 4.3E-22 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 431 445 4.3E-22 T 22-04-2016 TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 433 439 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site TOLA_RS08890 6c46cf1dc5a31881b70c1e72d36c2b57 734 Gene3D G3DSA:3.40.1110.10 445 555 1.3E-14 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 TOLA_RS07275 458641f4bff8e39ac737c8de1ed160fa 225 SMART SM01144 25 219 1.1E-72 T 22-04-2016 IPR005636 DTW TOLA_RS07275 458641f4bff8e39ac737c8de1ed160fa 225 Pfam PF03942 DTW domain 28 214 1.8E-40 T 22-04-2016 IPR005636 DTW TOLA_RS07275 458641f4bff8e39ac737c8de1ed160fa 225 PANTHER PTHR21392:SF1 1 224 7.0E-97 T 22-04-2016 TOLA_RS07275 458641f4bff8e39ac737c8de1ed160fa 225 PANTHER PTHR21392 1 224 7.0E-97 T 22-04-2016 TOLA_RS01360 4b23a514cb2dec5a26450f66f4547273 489 Pfam PF10150 Ribonuclease E/G family 124 393 3.4E-102 T 22-04-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 TOLA_RS01360 4b23a514cb2dec5a26450f66f4547273 489 Gene3D G3DSA:2.40.50.140 30 128 1.8E-32 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS01360 4b23a514cb2dec5a26450f66f4547273 489 PANTHER PTHR30001 1 489 8.6E-226 T 22-04-2016 TOLA_RS01360 4b23a514cb2dec5a26450f66f4547273 489 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 426 4.5E-173 T 22-04-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 TOLA_RS01360 4b23a514cb2dec5a26450f66f4547273 489 SMART SM00316 37 122 2.7E-7 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS01360 4b23a514cb2dec5a26450f66f4547273 489 Pfam PF00575 S1 RNA binding domain 38 120 3.3E-5 T 22-04-2016 IPR003029 S1 domain GO:0003676 TOLA_RS01360 4b23a514cb2dec5a26450f66f4547273 489 SUPERFAMILY SSF50249 39 128 1.11E-18 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 Gene3D G3DSA:1.10.645.10 219 434 2.3E-34 T 22-04-2016 IPR029014 NiFe hydrogenase-like TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 Hamap MF_01359 NADH-quinone oxidoreductase subunit C/D [nuoC]. 18 602 69.442 T 22-04-2016 IPR023062 NADH dehydrogenase, subunit CD GO:0030964|GO:0050136|GO:0055114 KEGG: 00190+1.6.5.11 TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 SUPERFAMILY SSF143243 26 231 8.63E-57 T 22-04-2016 TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 52 180 3.2E-38 T 22-04-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 254 265 - T 22-04-2016 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 PANTHER PTHR11993 149 597 3.9E-295 T 22-04-2016 TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 107 162 2.0E-19 T 22-04-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 PANTHER PTHR11993:SF28 149 597 3.9E-295 T 22-04-2016 TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 331 602 4.7E-106 T 22-04-2016 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 51 178 1.1E-37 T 22-04-2016 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 Gene3D G3DSA:1.10.645.10 435 584 3.3E-15 T 22-04-2016 IPR029014 NiFe hydrogenase-like TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 217 602 5.4E-170 T 22-04-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 SUPERFAMILY SSF56762 227 602 2.88E-123 T 22-04-2016 IPR029014 NiFe hydrogenase-like TOLA_RS13445 74440df7c499f6d8ec115ce2a69440ae 602 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 213 602 42.95 T 22-04-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 TOLA_RS03600 b7665ae87fca5eeb04e7e4a9ef40152e 89 Pfam PF08681 Protein of unknown function (DUF1778) 7 86 5.5E-24 T 22-04-2016 IPR014795 Vibrio phage ICP1, Orf50 TOLA_RS03600 b7665ae87fca5eeb04e7e4a9ef40152e 89 PANTHER PTHR35401 1 89 3.1E-27 T 22-04-2016 TOLA_RS03600 b7665ae87fca5eeb04e7e4a9ef40152e 89 PANTHER PTHR35401:SF2 1 89 3.1E-27 T 22-04-2016 TOLA_RS03600 b7665ae87fca5eeb04e7e4a9ef40152e 89 Gene3D G3DSA:1.20.890.30 50 89 1.6E-21 T 22-04-2016 TOLA_RS03600 b7665ae87fca5eeb04e7e4a9ef40152e 89 Gene3D G3DSA:1.10.1220.10 1 49 6.2E-26 T 22-04-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TOLA_RS03600 b7665ae87fca5eeb04e7e4a9ef40152e 89 SUPERFAMILY SSF47598 6 82 1.02E-19 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 TOLA_RS03895 25215e769d957eca493e9585d1e1e967 449 Gene3D G3DSA:3.20.20.140 70 415 1.4E-100 T 22-04-2016 TOLA_RS03895 25215e769d957eca493e9585d1e1e967 449 PANTHER PTHR11647 1 447 1.1E-139 T 22-04-2016 TOLA_RS03895 25215e769d957eca493e9585d1e1e967 449 SUPERFAMILY SSF51556 55 376 4.86E-92 T 22-04-2016 IPR032466 Metal-dependent hydrolase TOLA_RS03895 25215e769d957eca493e9585d1e1e967 449 ProSitePatterns PS00483 Dihydroorotase signature 2. 311 322 - T 22-04-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS03895 25215e769d957eca493e9585d1e1e967 449 SUPERFAMILY SSF51338 2 54 5.02E-31 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 TOLA_RS03895 25215e769d957eca493e9585d1e1e967 449 SUPERFAMILY SSF51338 375 438 5.02E-31 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 TOLA_RS03895 25215e769d957eca493e9585d1e1e967 449 Gene3D G3DSA:2.30.40.10 3 69 8.0E-23 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 TOLA_RS03895 25215e769d957eca493e9585d1e1e967 449 PANTHER PTHR11647:SF1 1 447 1.1E-139 T 22-04-2016 TOLA_RS03895 25215e769d957eca493e9585d1e1e967 449 Pfam PF01979 Amidohydrolase family 52 428 8.5E-19 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 Gene3D G3DSA:1.10.580.10 52 280 4.0E-98 T 22-04-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 SUPERFAMILY SSF48256 6 428 4.84E-164 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 ProSitePatterns PS00480 Citrate synthase signature. 303 315 - T 22-04-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 PANTHER PTHR11739 39 429 7.0E-198 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 Pfam PF00285 Citrate synthase, C-terminal domain 48 412 6.1E-130 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 PIRSF PIRSF001369 38 430 2.7E-167 T 22-04-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 15 422 6.4E-232 T 22-04-2016 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 UniPathway: UPA00223 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 PRINTS PR00143 Citrate synthase signature 360 376 1.1E-55 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 PRINTS PR00143 Citrate synthase signature 380 394 1.1E-55 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 PRINTS PR00143 Citrate synthase signature 219 234 1.1E-55 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 PRINTS PR00143 Citrate synthase signature 296 316 1.1E-55 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 PRINTS PR00143 Citrate synthase signature 241 269 1.1E-55 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 PRINTS PR00143 Citrate synthase signature 165 178 1.1E-55 T 22-04-2016 IPR002020 Citrate synthase GO:0046912 TOLA_RS11320 69a47d209eb9cfef9d588d593962acda 430 Gene3D G3DSA:1.10.230.10 281 373 2.2E-41 T 22-04-2016 IPR016143 Citrate synthase-like, small alpha subdomain TOLA_RS03390 742aaae73a09d66c649ded1cf594a686 97 TIGRFAM TIGR02936 fdxN_nitrog: ferredoxin III, nif-specific 7 93 3.6E-35 T 22-04-2016 IPR014283 Ferredoxin III 4[4Fe-4S], nif-specific TOLA_RS03390 742aaae73a09d66c649ded1cf594a686 97 Pfam PF14697 4Fe-4S dicluster domain 23 89 1.7E-10 T 22-04-2016 TOLA_RS03390 742aaae73a09d66c649ded1cf594a686 97 Gene3D G3DSA:3.30.70.20 8 91 5.2E-15 T 22-04-2016 TOLA_RS03390 742aaae73a09d66c649ded1cf594a686 97 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS03390 742aaae73a09d66c649ded1cf594a686 97 SUPERFAMILY SSF46548 12 92 1.26E-16 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 SUPERFAMILY SSF140356 3 105 5.36E-32 T 22-04-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 SUPERFAMILY SSF56024 318 495 2.88E-53 T 22-04-2016 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 7 678 2.1E-257 T 22-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 SUPERFAMILY SSF143724 107 313 6.87E-59 T 22-04-2016 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 PANTHER PTHR30218:SF0 1 690 0.0 T 22-04-2016 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 Hamap MF_00347 Polyphosphate kinase [ppk]. 4 682 30.939 T 22-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 Pfam PF13089 Polyphosphate kinase N-terminal domain 8 110 2.6E-30 T 22-04-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 Pfam PF13090 Polyphosphate kinase C-terminal domain 331 677 5.6E-147 T 22-04-2016 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 PANTHER PTHR30218 1 690 0.0 T 22-04-2016 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 Gene3D G3DSA:3.30.870.10 501 682 1.3E-71 T 22-04-2016 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 PIRSF PIRSF015589 1 688 2.7E-241 T 22-04-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 Gene3D G3DSA:3.30.1840.10 106 301 1.4E-51 T 22-04-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 Gene3D G3DSA:3.30.870.10 321 500 2.2E-70 T 22-04-2016 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 SUPERFAMILY SSF56024 501 682 2.47E-71 T 22-04-2016 TOLA_RS10485 bc25d913df556718a84b84798a7e48b9 690 Pfam PF02503 Polyphosphate kinase middle domain 119 315 4.9E-43 T 22-04-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 TOLA_RS12245 74f6a2e082a5606b71acc94492fa5629 530 Gene3D G3DSA:3.30.565.10 7 138 7.4E-10 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS12245 74f6a2e082a5606b71acc94492fa5629 530 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 106 3.9E-6 T 22-04-2016 TOLA_RS12245 74f6a2e082a5606b71acc94492fa5629 530 SUPERFAMILY SSF55874 22 140 2.62E-12 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS05665 e3d3727554c886c7b452c433d9934aad 487 SUPERFAMILY SSF53720 15 484 2.09E-166 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 TOLA_RS05665 e3d3727554c886c7b452c433d9934aad 487 Gene3D G3DSA:3.40.605.10 21 271 3.8E-91 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 TOLA_RS05665 e3d3727554c886c7b452c433d9934aad 487 Pfam PF00171 Aldehyde dehydrogenase family 23 480 2.4E-168 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 TOLA_RS05665 e3d3727554c886c7b452c433d9934aad 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 22-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 TOLA_RS05665 e3d3727554c886c7b452c433d9934aad 487 PANTHER PTHR11699:SF49 20 483 1.7E-280 T 22-04-2016 TOLA_RS05665 e3d3727554c886c7b452c433d9934aad 487 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 285 296 - T 22-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 TOLA_RS05665 e3d3727554c886c7b452c433d9934aad 487 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 32 479 3.7E-210 T 22-04-2016 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 UniPathway: UPA00733 TOLA_RS05665 e3d3727554c886c7b452c433d9934aad 487 Gene3D G3DSA:3.40.309.10 272 461 2.2E-71 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 TOLA_RS05665 e3d3727554c886c7b452c433d9934aad 487 PANTHER PTHR11699 20 483 1.7E-280 T 22-04-2016 TOLA_RS02905 9ffb2b07463b41e89cb69984ce2dc33d 325 PANTHER PTHR13794:SF60 1 305 1.6E-100 T 22-04-2016 TOLA_RS02905 9ffb2b07463b41e89cb69984ce2dc33d 325 SUPERFAMILY SSF51604 117 316 3.41E-51 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS02905 9ffb2b07463b41e89cb69984ce2dc33d 325 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 2 108 9.9E-15 T 22-04-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TOLA_RS02905 9ffb2b07463b41e89cb69984ce2dc33d 325 PANTHER PTHR13794 1 305 1.6E-100 T 22-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 TOLA_RS02905 9ffb2b07463b41e89cb69984ce2dc33d 325 Pfam PF13378 Enolase C-terminal domain-like 136 289 2.8E-26 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS02905 9ffb2b07463b41e89cb69984ce2dc33d 325 Gene3D G3DSA:3.30.390.10 1 101 2.0E-41 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TOLA_RS02905 9ffb2b07463b41e89cb69984ce2dc33d 325 Gene3D G3DSA:3.20.20.120 118 314 7.4E-57 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS02905 9ffb2b07463b41e89cb69984ce2dc33d 325 SUPERFAMILY SSF54826 2 110 1.22E-30 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TOLA_RS02905 9ffb2b07463b41e89cb69984ce2dc33d 325 SMART SM00922 129 220 2.2E-15 T 22-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 SUPERFAMILY SSF51395 462 1241 1.06E-259 T 22-04-2016 TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 Pfam PF00310 Glutamine amidotransferases class-II 21 444 1.3E-187 T 22-04-2016 IPR017932 Glutamine amidotransferase type 2 domain TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 Gene3D G3DSA:2.160.20.60 1260 1541 1.4E-109 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 Gene3D G3DSA:3.20.20.70 455 806 5.1E-108 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 Pfam PF01645 Conserved region in glutamate synthase 816 1206 1.3E-154 T 22-04-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 PANTHER PTHR11938 10 1536 0.0 T 22-04-2016 TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 Gene3D G3DSA:3.60.20.10 21 454 6.2E-190 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 SUPERFAMILY SSF69336 1255 1535 6.15E-97 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 Pfam PF04898 Glutamate synthase central domain 471 755 4.9E-109 T 22-04-2016 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 UniPathway: UPA00045 TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 Gene3D G3DSA:3.20.20.70 854 1241 6.8E-183 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 Pfam PF01493 GXGXG motif 1286 1470 1.3E-80 T 22-04-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 SUPERFAMILY SSF56235 21 446 6.56E-157 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS02525 204827afb09de66dfe4047bb2376dbc2 1544 PANTHER PTHR11938:SF1 10 1536 0.0 T 22-04-2016 TOLA_RS03060 4643cacb52f1984b5cfd2c3ec5b3580a 908 Gene3D G3DSA:3.40.50.300 7 235 1.8E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03060 4643cacb52f1984b5cfd2c3ec5b3580a 908 Gene3D G3DSA:3.40.50.300 265 495 3.8E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03060 4643cacb52f1984b5cfd2c3ec5b3580a 908 Pfam PF00005 ABC transporter 22 169 2.1E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS03060 4643cacb52f1984b5cfd2c3ec5b3580a 908 Pfam PF00005 ABC transporter 286 430 3.2E-26 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS03060 4643cacb52f1984b5cfd2c3ec5b3580a 908 Pfam PF12698 ABC-2 family transporter protein 560 900 2.0E-38 T 22-04-2016 TOLA_RS03060 4643cacb52f1984b5cfd2c3ec5b3580a 908 SUPERFAMILY SSF52540 9 232 8.05E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03060 4643cacb52f1984b5cfd2c3ec5b3580a 908 PANTHER PTHR24220 8 390 1.3E-219 T 22-04-2016 TOLA_RS03060 4643cacb52f1984b5cfd2c3ec5b3580a 908 SUPERFAMILY SSF52540 263 493 1.13E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03060 4643cacb52f1984b5cfd2c3ec5b3580a 908 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS03060 4643cacb52f1984b5cfd2c3ec5b3580a 908 SMART SM00382 31 248 4.6E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS03060 4643cacb52f1984b5cfd2c3ec5b3580a 908 SMART SM00382 295 486 2.2E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS03060 4643cacb52f1984b5cfd2c3ec5b3580a 908 PANTHER PTHR24220:SF388 8 390 1.3E-219 T 22-04-2016 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 SUPERFAMILY SSF52540 167 487 3.97E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 PANTHER PTHR11638:SF11 1 862 0.0 T 22-04-2016 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 PANTHER PTHR11638 1 862 0.0 T 22-04-2016 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 SMART SM01086 774 866 1.7E-7 T 22-04-2016 IPR019489 Clp ATPase, C-terminal TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 Pfam PF07724 AAA domain (Cdc48 subfamily) 603 769 1.2E-39 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 670 3.3E-31 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 714 728 3.3E-31 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 681 699 3.3E-31 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 607 625 3.3E-31 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 SUPERFAMILY SSF52540 552 846 2.26E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 Gene3D G3DSA:3.40.50.300 569 785 1.1E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 301 313 - T 22-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 Gene3D G3DSA:1.10.1780.10 18 129 3.8E-10 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 14 856 0.0 T 22-04-2016 IPR017729 Type VI secretion system, ATPase ClpV1 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 Gene3D G3DSA:1.10.8.60 786 852 1.2E-10 T 22-04-2016 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 Gene3D G3DSA:1.10.8.60 352 430 2.9E-26 T 22-04-2016 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 637 655 - T 22-04-2016 IPR028299 ClpA/B, conserved site 2 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 210 315 1.0E-9 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 777 847 2.4E-12 T 22-04-2016 IPR019489 Clp ATPase, C-terminal TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 Gene3D G3DSA:3.40.50.300 167 348 4.5E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 SUPERFAMILY SSF81923 18 128 5.3E-9 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 SMART SM00382 205 351 3.8E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS01075 c49064a034d98d82033ca3a01baf5839 869 SMART SM00382 603 747 8.6E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS02655 f8ef9469cbaa9a5a0559739463289853 261 Pfam PF00561 alpha/beta hydrolase fold 14 242 2.2E-22 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS02655 f8ef9469cbaa9a5a0559739463289853 261 SUPERFAMILY SSF53474 2 255 4.36E-55 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS02655 f8ef9469cbaa9a5a0559739463289853 261 Hamap MF_01260 Pimeloyl-[acyl-carrier protein] methyl ester esterase [bioH]. 3 254 42.818 T 22-04-2016 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519|UniPathway: UPA00078 TOLA_RS02655 f8ef9469cbaa9a5a0559739463289853 261 PANTHER PTHR10992:SF812 2 255 2.7E-86 T 22-04-2016 TOLA_RS02655 f8ef9469cbaa9a5a0559739463289853 261 PANTHER PTHR10992 2 255 2.7E-86 T 22-04-2016 TOLA_RS02655 f8ef9469cbaa9a5a0559739463289853 261 TIGRFAM TIGR01738 bioH: pimelyl-[acyl-carrier protein] methyl ester esterase 9 252 1.2E-82 T 22-04-2016 IPR010076 Pimeloyl-[acyl-carrier protein] methyl ester esterase GO:0009102|GO:0052689 KEGG: 00780+3.1.1.85|MetaCyc: PWY-6519|UniPathway: UPA00078 TOLA_RS02655 f8ef9469cbaa9a5a0559739463289853 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 199 213 7.2E-15 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS02655 f8ef9469cbaa9a5a0559739463289853 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 7.2E-15 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS02655 f8ef9469cbaa9a5a0559739463289853 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 7.2E-15 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS02655 f8ef9469cbaa9a5a0559739463289853 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 78 91 7.2E-15 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS02655 f8ef9469cbaa9a5a0559739463289853 261 Gene3D G3DSA:3.40.50.1820 2 255 1.1E-59 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS14115 063cbbc686dbbf29535a401c17516c04 302 Gene3D G3DSA:1.20.1510.10 18 209 2.2E-38 T 22-04-2016 IPR027469 Cation efflux protein transmembrane domain TOLA_RS14115 063cbbc686dbbf29535a401c17516c04 302 PANTHER PTHR11562:SF55 8 299 4.7E-98 T 22-04-2016 TOLA_RS14115 063cbbc686dbbf29535a401c17516c04 302 Pfam PF16916 Dimerisation domain of Zinc Transporter 213 290 1.5E-24 T 22-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain TOLA_RS14115 063cbbc686dbbf29535a401c17516c04 302 Gene3D G3DSA:3.30.70.1350 210 290 4.8E-27 T 22-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain TOLA_RS14115 063cbbc686dbbf29535a401c17516c04 302 SUPERFAMILY SSF161111 10 210 8.63E-47 T 22-04-2016 TOLA_RS14115 063cbbc686dbbf29535a401c17516c04 302 Pfam PF01545 Cation efflux family 17 209 3.3E-33 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TOLA_RS14115 063cbbc686dbbf29535a401c17516c04 302 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 18 290 4.0E-63 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TOLA_RS14115 063cbbc686dbbf29535a401c17516c04 302 SUPERFAMILY SSF160240 213 290 1.06E-23 T 22-04-2016 TOLA_RS14115 063cbbc686dbbf29535a401c17516c04 302 PANTHER PTHR11562 8 299 4.7E-98 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TOLA_RS11250 0742f2a0a611482ecd2492bd30283d41 110 PIRSF PIRSF004555 3 110 1.3E-39 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family TOLA_RS11250 0742f2a0a611482ecd2492bd30283d41 110 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 106 9.0E-39 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family TOLA_RS11250 0742f2a0a611482ecd2492bd30283d41 110 SUPERFAMILY SSF82607 11 104 3.14E-35 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family TOLA_RS11250 0742f2a0a611482ecd2492bd30283d41 110 PANTHER PTHR33449:SF1 1 110 1.1E-52 T 22-04-2016 TOLA_RS11250 0742f2a0a611482ecd2492bd30283d41 110 Pfam PF02575 YbaB/EbfC DNA-binding family 11 101 3.3E-36 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family TOLA_RS11250 0742f2a0a611482ecd2492bd30283d41 110 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 5 99 23.257 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family TOLA_RS11250 0742f2a0a611482ecd2492bd30283d41 110 PANTHER PTHR33449 1 110 1.1E-52 T 22-04-2016 TOLA_RS11250 0742f2a0a611482ecd2492bd30283d41 110 Gene3D G3DSA:3.30.1310.10 1 110 3.6E-50 T 22-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family TOLA_RS13370 b5a1dd0d84da9616bc9a8cfb785093ff 482 Pfam PF08323 Starch synthase catalytic domain 2 238 4.2E-74 T 22-04-2016 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS13370 b5a1dd0d84da9616bc9a8cfb785093ff 482 PANTHER PTHR12526 1 479 2.9E-123 T 22-04-2016 TOLA_RS13370 b5a1dd0d84da9616bc9a8cfb785093ff 482 PANTHER PTHR12526:SF17 1 479 2.9E-123 T 22-04-2016 TOLA_RS13370 b5a1dd0d84da9616bc9a8cfb785093ff 482 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 477 2.6E-161 T 22-04-2016 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS13370 b5a1dd0d84da9616bc9a8cfb785093ff 482 Hamap MF_00484 Glycogen synthase [glgA]. 1 478 39.32 T 22-04-2016 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 TOLA_RS13370 b5a1dd0d84da9616bc9a8cfb785093ff 482 SUPERFAMILY SSF53756 2 480 1.68E-115 T 22-04-2016 TOLA_RS13370 b5a1dd0d84da9616bc9a8cfb785093ff 482 Gene3D G3DSA:3.40.50.2000 254 458 2.7E-68 T 22-04-2016 TOLA_RS13370 b5a1dd0d84da9616bc9a8cfb785093ff 482 Pfam PF00534 Glycosyl transferases group 1 295 441 5.8E-15 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 TOLA_RS06555 682fe0b21c8b58be7a52c90abd635a16 147 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 134 1.2E-40 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 TOLA_RS06555 682fe0b21c8b58be7a52c90abd635a16 147 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 22-04-2016 IPR019823 Large-conductance mechanosensitive channel, conserved site TOLA_RS06555 682fe0b21c8b58be7a52c90abd635a16 147 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 103 112 1.9E-12 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 TOLA_RS06555 682fe0b21c8b58be7a52c90abd635a16 147 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 94 102 1.9E-12 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 TOLA_RS06555 682fe0b21c8b58be7a52c90abd635a16 147 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 1.9E-12 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 TOLA_RS06555 682fe0b21c8b58be7a52c90abd635a16 147 SUPERFAMILY SSF81330 10 133 1.57E-36 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 TOLA_RS06555 682fe0b21c8b58be7a52c90abd635a16 147 PANTHER PTHR30266 1 147 4.9E-57 T 22-04-2016 TOLA_RS06555 682fe0b21c8b58be7a52c90abd635a16 147 PANTHER PTHR30266:SF2 1 147 4.9E-57 T 22-04-2016 TOLA_RS06555 682fe0b21c8b58be7a52c90abd635a16 147 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 140 24.359 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 TOLA_RS06555 682fe0b21c8b58be7a52c90abd635a16 147 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 2 120 2.0E-36 T 22-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 TOLA_RS02990 346ee249023d6881d825f87eb068c525 431 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 7 430 107.622 T 22-04-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188|UniPathway: UPA00251 TOLA_RS02990 346ee249023d6881d825f87eb068c525 431 Pfam PF00202 Aminotransferase class-III 36 400 1.0E-79 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS02990 346ee249023d6881d825f87eb068c525 431 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 8 429 3.9E-196 T 22-04-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188|UniPathway: UPA00251 TOLA_RS02990 346ee249023d6881d825f87eb068c525 431 PANTHER PTHR11986:SF5 3 431 1.8E-234 T 22-04-2016 TOLA_RS02990 346ee249023d6881d825f87eb068c525 431 PANTHER PTHR11986 3 431 1.8E-234 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS02990 346ee249023d6881d825f87eb068c525 431 SUPERFAMILY SSF53383 4 429 1.51E-140 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS02990 346ee249023d6881d825f87eb068c525 431 Gene3D G3DSA:3.40.640.10 74 320 1.5E-84 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS02990 346ee249023d6881d825f87eb068c525 431 Gene3D G3DSA:3.90.1150.10 4 73 4.9E-48 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS02990 346ee249023d6881d825f87eb068c525 431 Gene3D G3DSA:3.90.1150.10 323 429 4.9E-48 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS02990 346ee249023d6881d825f87eb068c525 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 274 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 PANTHER PTHR24093 5 886 0.0 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 Pfam PF00122 E1-E2 ATPase 87 319 5.6E-62 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 330 336 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 SUPERFAMILY SSF56784 326 346 1.14E-62 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 SUPERFAMILY SSF56784 466 715 1.14E-62 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 350 1.4E-41 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 584 697 1.6E-32 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 388 553 9.7E-23 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 Pfam PF00702 haloacid dehalogenase-like hydrolase 325 624 1.9E-23 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 Gene3D G3DSA:3.40.50.1000 514 579 2.1E-4 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 Gene3D G3DSA:1.20.1110.10 580 882 4.2E-97 T 22-04-2016 IPR023298 P-type ATPase, transmembrane domain TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 Gene3D G3DSA:1.20.1110.10 55 114 4.2E-97 T 22-04-2016 IPR023298 P-type ATPase, transmembrane domain TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 Gene3D G3DSA:2.70.150.10 18 54 5.9E-41 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 Gene3D G3DSA:2.70.150.10 115 227 5.9E-41 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 SUPERFAMILY SSF81660 335 510 1.05E-39 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 Pfam PF00690 Cation transporter/ATPase, N-terminus 5 69 5.8E-19 T 22-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 634 646 2.726287E-39 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 328 342 2.726287E-39 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 610 629 2.726287E-39 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 167 181 2.726287E-39 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 506 517 2.726287E-39 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 528 538 2.726287E-39 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 248 270 1.285604E-16 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 321 342 1.285604E-16 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 62 76 1.285604E-16 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 Pfam PF00689 Cation transporting ATPase, C-terminus 694 879 7.1E-48 T 22-04-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 Gene3D G3DSA:3.40.1110.10 318 513 6.1E-51 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 PANTHER PTHR24093:SF268 5 886 0.0 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 SUPERFAMILY SSF81653 119 227 3.92E-26 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 SMART SM00831 2 75 4.4E-20 T 22-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 SUPERFAMILY SSF81665 660 885 2.62E-123 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 SUPERFAMILY SSF81665 229 322 2.62E-123 T 22-04-2016 TOLA_RS09360 80811cbddd96e61dfb7972c17c9c49cc 886 SUPERFAMILY SSF81665 5 120 2.62E-123 T 22-04-2016 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 Pfam PF02817 e3 binding domain 325 360 3.4E-15 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 Gene3D G3DSA:4.10.320.10 322 370 1.5E-21 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 SUPERFAMILY SSF51230 201 293 2.49E-22 T 22-04-2016 IPR011053 Single hybrid motif TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 SUPERFAMILY SSF51230 2 92 2.88E-23 T 22-04-2016 IPR011053 Single hybrid motif TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 187 629 6.7E-202 T 22-04-2016 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 SUPERFAMILY SSF47005 320 364 2.35E-13 T 22-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 Gene3D G3DSA:2.40.50.100 204 278 1.6E-21 T 22-04-2016 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 Gene3D G3DSA:2.40.50.100 104 178 3.2E-22 T 22-04-2016 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 Gene3D G3DSA:2.40.50.100 2 92 7.8E-22 T 22-04-2016 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 398 628 4.1E-75 T 22-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 Gene3D G3DSA:3.30.559.10 388 629 1.5E-78 T 22-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 PANTHER PTHR23151 21 218 1.6E-249 T 22-04-2016 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 PANTHER PTHR23151 322 629 1.6E-249 T 22-04-2016 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 Pfam PF00364 Biotin-requiring enzyme 104 173 5.0E-22 T 22-04-2016 IPR000089 Biotin/lipoyl attachment TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 Pfam PF00364 Biotin-requiring enzyme 4 73 2.5E-21 T 22-04-2016 IPR000089 Biotin/lipoyl attachment TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 Pfam PF00364 Biotin-requiring enzyme 203 273 1.9E-21 T 22-04-2016 IPR000089 Biotin/lipoyl attachment TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 125 154 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 225 254 - T 22-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 PANTHER PTHR23151:SF68 21 218 1.6E-249 T 22-04-2016 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 PANTHER PTHR23151:SF68 322 629 1.6E-249 T 22-04-2016 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 SUPERFAMILY SSF52777 387 628 4.09E-77 T 22-04-2016 TOLA_RS13095 7555291e3e1ce1a39e71d22758d01eb3 629 SUPERFAMILY SSF51230 102 191 4.19E-23 T 22-04-2016 IPR011053 Single hybrid motif TOLA_RS12725 0eadf8cb3ad63e5249524ca14a810fd4 124 PANTHER PTHR21011:SF1 1 124 1.3E-43 T 22-04-2016 TOLA_RS12725 0eadf8cb3ad63e5249524ca14a810fd4 124 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.969 T 22-04-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS12725 0eadf8cb3ad63e5249524ca14a810fd4 124 Pfam PF01250 Ribosomal protein S6 3 91 1.0E-28 T 22-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS12725 0eadf8cb3ad63e5249524ca14a810fd4 124 SUPERFAMILY SSF54995 1 103 6.41E-38 T 22-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS12725 0eadf8cb3ad63e5249524ca14a810fd4 124 Gene3D G3DSA:3.30.70.60 1 103 1.2E-42 T 22-04-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TOLA_RS12725 0eadf8cb3ad63e5249524ca14a810fd4 124 PANTHER PTHR21011 1 124 1.3E-43 T 22-04-2016 TOLA_RS12725 0eadf8cb3ad63e5249524ca14a810fd4 124 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 2.5E-37 T 22-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS14415 027e0b95d7aef9764ad172cccb3a4b98 167 Gene3D G3DSA:3.40.470.10 7 165 8.2E-35 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like TOLA_RS14415 027e0b95d7aef9764ad172cccb3a4b98 167 SUPERFAMILY SSF52141 7 165 1.7E-35 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like TOLA_RS14415 027e0b95d7aef9764ad172cccb3a4b98 167 SMART SM00987 8 164 2.3E-10 T 22-04-2016 TOLA_RS14415 027e0b95d7aef9764ad172cccb3a4b98 167 SMART SM00986 8 164 2.3E-10 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like TOLA_RS14415 027e0b95d7aef9764ad172cccb3a4b98 167 Pfam PF03167 Uracil DNA glycosylase superfamily 11 162 3.8E-10 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like TOLA_RS14415 027e0b95d7aef9764ad172cccb3a4b98 167 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 6 160 2.8E-48 T 22-04-2016 IPR026353 Hypoxanthine-DNA glycosylase TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 PANTHER PTHR32071:SF38 1 332 8.1E-170 T 22-04-2016 TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 Gene3D G3DSA:1.10.8.60 180 250 1.4E-19 T 22-04-2016 TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 Pfam PF00158 Sigma-54 interaction domain 8 170 5.9E-60 T 22-04-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 94 109 - T 22-04-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 SUPERFAMILY SSF46689 222 332 1.7E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 PANTHER PTHR32071 1 332 8.1E-170 T 22-04-2016 TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 SUPERFAMILY SSF52540 7 243 1.95E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 Gene3D G3DSA:1.10.10.60 287 332 3.1E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 Gene3D G3DSA:3.40.50.300 4 178 4.0E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 SMART SM00382 28 180 5.3E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 TIGRFAM TIGR02974 phageshock_pspF: psp operon transcriptional activator 8 332 3.6E-153 T 22-04-2016 IPR014317 Transcription activator PspF TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 222 231 - T 22-04-2016 IPR025944 Sigma-54 interaction domain, conserved site TOLA_RS00465 f6c0adbc7760e5bae2dfbc1d2eab1f0c 344 Pfam PF02954 Bacterial regulatory protein, Fis family 292 332 1.9E-8 T 22-04-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 Pfam PF00271 Helicase conserved C-terminal domain 209 328 1.7E-13 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 PIRSF PIRSF005496 1 813 4.3E-294 T 22-04-2016 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 SMART SM00847 387 501 1.9E-5 T 22-04-2016 IPR007502 Helicase-associated domain GO:0004386 TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 Pfam PF04408 Helicase associated domain (HA2) 389 450 7.7E-7 T 22-04-2016 IPR007502 Helicase-associated domain GO:0004386 TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 SMART SM00487 5 188 1.3E-16 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 Pfam PF00270 DEAD/DEAH box helicase 18 160 2.1E-9 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 4 811 0.0 T 22-04-2016 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 Gene3D G3DSA:3.40.50.300 210 345 1.3E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 SUPERFAMILY SSF52540 178 425 6.29E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 SMART SM00490 226 328 2.3E-21 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 PANTHER PTHR18934 3 424 5.1E-135 T 22-04-2016 TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 Gene3D G3DSA:3.40.50.300 3 160 1.8E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 Pfam PF08482 ATP-dependent helicase C-terminal 668 800 1.3E-51 T 22-04-2016 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal TOLA_RS04050 e22c495d818ce4278833aa1cb572de35 813 SUPERFAMILY SSF52540 15 159 1.75E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 Gene3D G3DSA:3.40.50.80 261 396 4.0E-31 T 22-04-2016 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 PANTHER PTHR22924:SF49 8 393 2.7E-142 T 22-04-2016 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 Pfam PF00175 Oxidoreductase NAD-binding domain 271 372 2.7E-14 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 Pfam PF00042 Globin 5 101 5.7E-12 T 22-04-2016 IPR000971 Globin GO:0019825|GO:0020037 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 SUPERFAMILY SSF46458 1 142 7.98E-42 T 22-04-2016 IPR009050 Globin-like TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 SUPERFAMILY SSF52343 250 390 1.96E-30 T 22-04-2016 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 SUPERFAMILY SSF63380 150 261 7.66E-25 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 Gene3D G3DSA:1.10.490.10 1 142 3.0E-55 T 22-04-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 Hamap MF_01252 Flavohemoprotein [hmp]. 1 398 52.062 T 22-04-2016 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 Gene3D G3DSA:2.40.30.10 150 260 2.3E-31 T 22-04-2016 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 Pfam PF00970 Oxidoreductase FAD-binding domain 159 259 4.8E-5 T 22-04-2016 IPR008333 Oxidoreductase, FAD-binding domain TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 PRINTS PR00410 Phenol hydroxylase reductase family signature 270 289 4.3E-8 T 22-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 PRINTS PR00410 Phenol hydroxylase reductase family signature 202 214 4.3E-8 T 22-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 PRINTS PR00410 Phenol hydroxylase reductase family signature 360 368 4.3E-8 T 22-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 360 368 3.8E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 184 194 3.8E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 270 289 3.8E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 205 212 3.8E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS09350 1fc1fd6f02a2cea3f687fabbbe8f6ab4 398 PANTHER PTHR22924 8 393 2.7E-142 T 22-04-2016 TOLA_RS02280 267955f05887fc1b093dcf4d2187d0ad 190 Pfam PF04220 Der GTPase activator (YihI) 14 173 2.1E-48 T 22-04-2016 IPR007336 Der GTPase activator TOLA_RS02280 267955f05887fc1b093dcf4d2187d0ad 190 Hamap MF_01058 Der GTPase-activating protein YihI [yihI]. 2 176 14.792 T 22-04-2016 IPR007336 Der GTPase activator TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 PANTHER PTHR21262:SF5 41 743 0.0 T 22-04-2016 TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 Pfam PF02824 TGS domain 402 461 1.1E-20 T 22-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 PANTHER PTHR21262 41 743 0.0 T 22-04-2016 TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 SUPERFAMILY SSF81301 193 406 9.05E-66 T 22-04-2016 TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 Pfam PF13291 ACT domain 665 742 7.1E-18 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 Pfam PF04607 Region found in RelA / SpoT proteins 248 358 3.2E-38 T 22-04-2016 IPR007685 RelA/SpoT GO:0015969 TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 Gene3D G3DSA:3.30.460.10 191 337 4.2E-53 T 22-04-2016 TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 SUPERFAMILY SSF109604 14 204 3.77E-43 T 22-04-2016 TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 Pfam PF13328 HD domain 43 188 1.5E-36 T 22-04-2016 IPR003607 HD/PDEase domain TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 SUPERFAMILY SSF81271 394 461 2.18E-21 T 22-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 Gene3D G3DSA:3.10.20.30 402 463 1.7E-25 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 62 742 1.9E-192 T 22-04-2016 IPR004811 RelA/SpoT family GO:0015969 TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 SMART SM00954 248 358 3.9E-66 T 22-04-2016 IPR007685 RelA/SpoT GO:0015969 TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 SUPERFAMILY SSF55021 670 742 1.18E-11 T 22-04-2016 TOLA_RS14030 86df18c9363fd7cd14bf4fa5502b0b34 743 Gene3D G3DSA:3.30.70.260 666 740 1.8E-23 T 22-04-2016 TOLA_RS10430 b66f5528eef1f1c762767ba36c894e3d 321 PANTHER PTHR10366 5 321 1.0E-131 T 22-04-2016 TOLA_RS10430 b66f5528eef1f1c762767ba36c894e3d 321 Gene3D G3DSA:3.40.50.720 220 258 4.3E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10430 b66f5528eef1f1c762767ba36c894e3d 321 Gene3D G3DSA:3.40.50.720 1 168 4.3E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10430 b66f5528eef1f1c762767ba36c894e3d 321 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 230 6.4E-74 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 TOLA_RS10430 b66f5528eef1f1c762767ba36c894e3d 321 SUPERFAMILY SSF51735 1 318 9.27E-74 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10430 b66f5528eef1f1c762767ba36c894e3d 321 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 3 314 48.952 T 22-04-2016 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00010+1.1.1.27|KEGG: 00051+1.1.1.271|KEGG: 00270+1.1.1.27|KEGG: 00520+1.1.1.271|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-66|MetaCyc: PWY-6901|UniPathway: UPA00128 TOLA_RS10430 b66f5528eef1f1c762767ba36c894e3d 321 Gene3D G3DSA:3.90.25.10 205 219 6.8E-15 T 22-04-2016 TOLA_RS10430 b66f5528eef1f1c762767ba36c894e3d 321 Gene3D G3DSA:3.90.25.10 300 319 6.8E-15 T 22-04-2016 TOLA_RS10430 b66f5528eef1f1c762767ba36c894e3d 321 PANTHER PTHR10366:SF246 5 321 1.0E-131 T 22-04-2016 TOLA_RS10430 b66f5528eef1f1c762767ba36c894e3d 321 Gene3D G3DSA:3.90.25.10 169 204 7.3E-38 T 22-04-2016 TOLA_RS10430 b66f5528eef1f1c762767ba36c894e3d 321 Gene3D G3DSA:3.90.25.10 259 299 7.3E-38 T 22-04-2016 TOLA_RS15915 6b556dda022ae1967611da82ba5ab929 468 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 363 371 - T 22-04-2016 IPR018120 Glycoside hydrolase family 1, active site TOLA_RS15915 6b556dda022ae1967611da82ba5ab929 468 Gene3D G3DSA:3.20.20.80 4 466 9.9E-146 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS15915 6b556dda022ae1967611da82ba5ab929 468 Pfam PF00232 Glycosyl hydrolase family 1 2 465 1.5E-138 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15915 6b556dda022ae1967611da82ba5ab929 468 PANTHER PTHR10353 4 468 3.0E-268 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15915 6b556dda022ae1967611da82ba5ab929 468 PANTHER PTHR10353:SF35 4 468 3.0E-268 T 22-04-2016 TOLA_RS15915 6b556dda022ae1967611da82ba5ab929 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 384 395 2.4E-16 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15915 6b556dda022ae1967611da82ba5ab929 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 405 422 2.4E-16 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15915 6b556dda022ae1967611da82ba5ab929 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 430 442 2.4E-16 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15915 6b556dda022ae1967611da82ba5ab929 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 363 371 2.4E-16 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15915 6b556dda022ae1967611da82ba5ab929 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 297 311 2.4E-16 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15915 6b556dda022ae1967611da82ba5ab929 468 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 22-04-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TOLA_RS15915 6b556dda022ae1967611da82ba5ab929 468 SUPERFAMILY SSF51445 3 467 6.84E-161 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS02560 a9e78cb000b953f6285ec4661d2a7691 193 Hamap MF_01104 Protein Syd [syd]. 3 179 30.66 T 22-04-2016 IPR009948 Syd GO:0009898 TOLA_RS02560 a9e78cb000b953f6285ec4661d2a7691 193 Pfam PF07348 Syd protein (SUKH-2) 8 177 2.8E-59 T 22-04-2016 IPR009948 Syd GO:0009898 TOLA_RS07300 b89c132e7d44627a348fdc7444dc7a69 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 189 2.5E-28 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS07300 b89c132e7d44627a348fdc7444dc7a69 222 Gene3D G3DSA:1.10.150.240 23 85 3.4E-6 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 TOLA_RS07300 b89c132e7d44627a348fdc7444dc7a69 222 SUPERFAMILY SSF56784 7 220 3.07E-52 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS07300 b89c132e7d44627a348fdc7444dc7a69 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 42 187 6.4E-10 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS07300 b89c132e7d44627a348fdc7444dc7a69 222 Gene3D G3DSA:3.40.50.1000 3 22 1.4E-38 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS07300 b89c132e7d44627a348fdc7444dc7a69 222 Gene3D G3DSA:3.40.50.1000 86 220 1.4E-38 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS07300 b89c132e7d44627a348fdc7444dc7a69 222 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 107 184 7.1E-10 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS07300 b89c132e7d44627a348fdc7444dc7a69 222 PANTHER PTHR18901:SF24 1 220 3.8E-74 T 22-04-2016 TOLA_RS07300 b89c132e7d44627a348fdc7444dc7a69 222 PANTHER PTHR18901 1 220 3.8E-74 T 22-04-2016 TOLA_RS03770 9089973b6852c18d5665034ad07a5145 100 Pfam PF10805 Protein of unknown function (DUF2730) 3 97 1.1E-31 T 22-04-2016 IPR020269 Bacteriophage Mu, Gp25 TOLA_RS03770 9089973b6852c18d5665034ad07a5145 100 ProDom PD283729 GP25 PHAGE SO2675 MEMBRANE MU-LIKE TRANSMEMBRANE HI1498 ECS4966 29 79 3.0E-10 T 22-04-2016 IPR020269 Bacteriophage Mu, Gp25 TOLA_RS15555 7f644d2c6fa4b6031a2cd45bd974f4c4 367 Gene3D G3DSA:3.60.15.10 85 352 6.1E-96 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS15555 7f644d2c6fa4b6031a2cd45bd974f4c4 367 Pfam PF12706 Beta-lactamase superfamily domain 108 300 1.1E-41 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS15555 7f644d2c6fa4b6031a2cd45bd974f4c4 367 SUPERFAMILY SSF56281 192 340 3.38E-34 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS15555 7f644d2c6fa4b6031a2cd45bd974f4c4 367 SUPERFAMILY SSF56281 90 165 3.38E-34 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS15555 7f644d2c6fa4b6031a2cd45bd974f4c4 367 PANTHER PTHR15032:SF4 89 357 4.9E-104 T 22-04-2016 TOLA_RS15555 7f644d2c6fa4b6031a2cd45bd974f4c4 367 PANTHER PTHR15032 89 357 4.9E-104 T 22-04-2016 TOLA_RS10255 a21a55798bafe10b6db1d25ab2ffd777 107 SUPERFAMILY SSF89360 1 96 9.94E-34 T 22-04-2016 IPR000361 FeS cluster biogenesis TOLA_RS10255 a21a55798bafe10b6db1d25ab2ffd777 107 PANTHER PTHR10072 1 107 3.8E-51 T 22-04-2016 TOLA_RS10255 a21a55798bafe10b6db1d25ab2ffd777 107 PANTHER PTHR10072:SF48 1 107 3.8E-51 T 22-04-2016 IPR031108 FeS assembly protein IscA-like GO:0005198|GO:0016226|GO:0051536 TOLA_RS10255 a21a55798bafe10b6db1d25ab2ffd777 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 1.3E-59 T 22-04-2016 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0016226|GO:0051536 TOLA_RS10255 a21a55798bafe10b6db1d25ab2ffd777 107 Gene3D G3DSA:2.60.300.12 2 96 6.2E-36 T 22-04-2016 IPR000361 FeS cluster biogenesis TOLA_RS10255 a21a55798bafe10b6db1d25ab2ffd777 107 Hamap MF_01429 Iron-binding protein IscA [iscA]. 1 107 38.336 T 22-04-2016 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0016226|GO:0051536 TOLA_RS10255 a21a55798bafe10b6db1d25ab2ffd777 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 4.5E-38 T 22-04-2016 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 TOLA_RS10255 a21a55798bafe10b6db1d25ab2ffd777 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 22-04-2016 IPR017870 FeS cluster insertion, C-terminal, conserved site TOLA_RS10255 a21a55798bafe10b6db1d25ab2ffd777 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 1.4E-26 T 22-04-2016 IPR000361 FeS cluster biogenesis TOLA_RS03015 9e2f416c8d501490eb7ca934f58e386e 229 Gene3D G3DSA:1.10.10.10 139 211 2.6E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS03015 9e2f416c8d501490eb7ca934f58e386e 229 SUPERFAMILY SSF55811 4 140 3.36E-24 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS03015 9e2f416c8d501490eb7ca934f58e386e 229 PANTHER PTHR22769:SF33 7 199 9.8E-21 T 22-04-2016 TOLA_RS03015 9e2f416c8d501490eb7ca934f58e386e 229 Gene3D G3DSA:3.90.79.10 4 135 1.2E-25 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS03015 9e2f416c8d501490eb7ca934f58e386e 229 SUPERFAMILY SSF46785 146 215 5.17E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS03015 9e2f416c8d501490eb7ca934f58e386e 229 PANTHER PTHR22769 7 199 9.8E-21 T 22-04-2016 TOLA_RS14270 3b483547aa3c1a2a631e67ef83d9dac2 142 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 1.1E-23 T 22-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TOLA_RS14270 3b483547aa3c1a2a631e67ef83d9dac2 142 Gene3D G3DSA:1.10.10.250 73 141 1.1E-29 T 22-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TOLA_RS14270 3b483547aa3c1a2a631e67ef83d9dac2 142 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 30.842 T 22-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TOLA_RS14270 3b483547aa3c1a2a631e67ef83d9dac2 142 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 3.0E-15 T 22-04-2016 TOLA_RS14270 3b483547aa3c1a2a631e67ef83d9dac2 142 SUPERFAMILY SSF54747 3 73 1.31E-29 T 22-04-2016 IPR020784 Ribosomal protein L11, N-terminal TOLA_RS14270 3b483547aa3c1a2a631e67ef83d9dac2 142 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 22-04-2016 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 TOLA_RS14270 3b483547aa3c1a2a631e67ef83d9dac2 142 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 8.2E-65 T 22-04-2016 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 TOLA_RS14270 3b483547aa3c1a2a631e67ef83d9dac2 142 SUPERFAMILY SSF46906 68 141 3.4E-25 T 22-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TOLA_RS14270 3b483547aa3c1a2a631e67ef83d9dac2 142 Gene3D G3DSA:3.30.1550.10 2 72 8.4E-38 T 22-04-2016 IPR020784 Ribosomal protein L11, N-terminal TOLA_RS14270 3b483547aa3c1a2a631e67ef83d9dac2 142 SMART SM00649 9 141 9.9E-83 T 22-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TOLA_RS14270 3b483547aa3c1a2a631e67ef83d9dac2 142 PANTHER PTHR11661 1 142 8.3E-71 T 22-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TOLA_RS14270 3b483547aa3c1a2a631e67ef83d9dac2 142 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 8.0E-29 T 22-04-2016 IPR020784 Ribosomal protein L11, N-terminal TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 PRINTS PR00148 Enolase signature 37 51 4.0E-44 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 PRINTS PR00148 Enolase signature 107 123 4.0E-44 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 PRINTS PR00148 Enolase signature 317 328 4.0E-44 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 PRINTS PR00148 Enolase signature 165 178 4.0E-44 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 PRINTS PR00148 Enolase signature 369 386 4.0E-44 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 PRINTS PR00148 Enolase signature 340 354 4.0E-44 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 SMART SM01193 4 134 1.5E-92 T 22-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 Gene3D G3DSA:3.20.20.120 128 429 2.1E-135 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 PIRSF PIRSF001400 1 431 7.5E-192 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 Pfam PF00113 Enolase, C-terminal TIM barrel domain 144 430 1.2E-137 T 22-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 ProSitePatterns PS00164 Enolase signature. 340 353 - T 22-04-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 SMART SM01192 143 431 3.4E-212 T 22-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 429 8.5E-207 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 SUPERFAMILY SSF54826 3 138 2.91E-56 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 Pfam PF03952 Enolase, N-terminal domain 4 134 6.9E-58 T 22-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 SUPERFAMILY SSF51604 144 428 1.1E-126 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 Hamap MF_00318 Enolase [eno]. 2 417 44.368 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 Gene3D G3DSA:3.30.390.10 3 127 4.0E-54 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TOLA_RS14015 d999cbc5d13f15e4592c7ac0056c75e0 433 PANTHER PTHR11902 1 428 1.3E-271 T 22-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS13160 255495eb7c87330c105f5cfe8a2147ad 268 Gene3D G3DSA:3.40.50.1000 182 267 4.5E-62 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13160 255495eb7c87330c105f5cfe8a2147ad 268 Gene3D G3DSA:3.40.50.1000 1 75 4.5E-62 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13160 255495eb7c87330c105f5cfe8a2147ad 268 SUPERFAMILY SSF56784 1 267 2.59E-79 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13160 255495eb7c87330c105f5cfe8a2147ad 268 ProSitePatterns PS01229 Hypothetical cof family signature 2. 216 238 - T 22-04-2016 TOLA_RS13160 255495eb7c87330c105f5cfe8a2147ad 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 80 2.4E-12 T 22-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 TOLA_RS13160 255495eb7c87330c105f5cfe8a2147ad 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 181 235 1.0E-11 T 22-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 TOLA_RS13160 255495eb7c87330c105f5cfe8a2147ad 268 PANTHER PTHR10000 1 268 7.4E-119 T 22-04-2016 TOLA_RS13160 255495eb7c87330c105f5cfe8a2147ad 268 PANTHER PTHR10000:SF29 1 268 7.4E-119 T 22-04-2016 TOLA_RS13160 255495eb7c87330c105f5cfe8a2147ad 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 262 1.5E-67 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13160 255495eb7c87330c105f5cfe8a2147ad 268 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 262 6.5E-64 T 22-04-2016 IPR000150 Cof protein GO:0016787 TOLA_RS13160 255495eb7c87330c105f5cfe8a2147ad 268 Gene3D G3DSA:3.30.1240.10 87 181 7.9E-32 T 22-04-2016 TOLA_RS15745 b16f5d9e1189eda0e89ede4ceea28b2c 159 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 151 1.6E-33 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15745 b16f5d9e1189eda0e89ede4ceea28b2c 159 Gene3D G3DSA:3.40.930.10 6 152 1.6E-49 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15745 b16f5d9e1189eda0e89ede4ceea28b2c 159 PANTHER PTHR36203 1 158 1.1E-59 T 22-04-2016 TOLA_RS15745 b16f5d9e1189eda0e89ede4ceea28b2c 159 SUPERFAMILY SSF55804 5 151 1.57E-32 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 TOLA_RS10860 693951b38360e0943e2c68e63a722980 383 Gene3D G3DSA:2.30.40.10 350 365 6.4E-7 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 TOLA_RS10860 693951b38360e0943e2c68e63a722980 383 Gene3D G3DSA:2.30.40.10 9 54 6.4E-7 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 TOLA_RS10860 693951b38360e0943e2c68e63a722980 383 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 1 376 6.1E-128 T 22-04-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395 TOLA_RS10860 693951b38360e0943e2c68e63a722980 383 Gene3D G3DSA:3.20.20.140 55 348 1.3E-93 T 22-04-2016 TOLA_RS10860 693951b38360e0943e2c68e63a722980 383 PANTHER PTHR11113 1 378 2.1E-139 T 22-04-2016 TOLA_RS10860 693951b38360e0943e2c68e63a722980 383 SUPERFAMILY SSF51556 54 350 1.3E-94 T 22-04-2016 IPR032466 Metal-dependent hydrolase TOLA_RS10860 693951b38360e0943e2c68e63a722980 383 PIRSF PIRSF038994 1 382 1.4E-109 T 22-04-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395 TOLA_RS10860 693951b38360e0943e2c68e63a722980 383 Pfam PF01979 Amidohydrolase family 51 378 2.0E-34 T 22-04-2016 IPR006680 Amidohydrolase-related GO:0016787 TOLA_RS10860 693951b38360e0943e2c68e63a722980 383 SUPERFAMILY SSF51338 1 53 1.16E-11 T 22-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 TOLA_RS10860 693951b38360e0943e2c68e63a722980 383 PANTHER PTHR11113:SF7 1 378 2.1E-139 T 22-04-2016 TOLA_RS05155 eb2032c66d6e51b3292f8365662eaff9 533 SUPERFAMILY SSF48317 91 286 1.31E-32 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TOLA_RS05155 eb2032c66d6e51b3292f8365662eaff9 533 Gene3D G3DSA:1.20.144.10 117 285 1.4E-25 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TOLA_RS05155 eb2032c66d6e51b3292f8365662eaff9 533 Pfam PF14067 LssY C-terminus 349 527 1.7E-47 T 22-04-2016 IPR025902 LssY-like C-terminal domain TOLA_RS05155 eb2032c66d6e51b3292f8365662eaff9 533 PANTHER PTHR14969 117 317 2.1E-20 T 22-04-2016 TOLA_RS05155 eb2032c66d6e51b3292f8365662eaff9 533 SMART SM00014 169 280 2.6E-16 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TOLA_RS05155 eb2032c66d6e51b3292f8365662eaff9 533 Pfam PF01569 PAP2 superfamily 173 283 1.5E-15 T 22-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TOLA_RS09615 82d671d8621c667ff732b898ca2b4d79 368 PIRSF PIRSF000112 1 361 1.3E-95 T 22-04-2016 TOLA_RS09615 82d671d8621c667ff732b898ca2b4d79 368 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 150 178 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS09615 82d671d8621c667ff732b898ca2b4d79 368 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 347 3.3E-68 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 TOLA_RS09615 82d671d8621c667ff732b898ca2b4d79 368 PANTHER PTHR11496 1 361 1.2E-177 T 22-04-2016 TOLA_RS09615 82d671d8621c667ff732b898ca2b4d79 368 Gene3D G3DSA:1.20.1090.10 160 364 6.5E-68 T 22-04-2016 TOLA_RS09615 82d671d8621c667ff732b898ca2b4d79 368 Gene3D G3DSA:3.40.50.1970 2 158 3.7E-45 T 22-04-2016 TOLA_RS09615 82d671d8621c667ff732b898ca2b4d79 368 PANTHER PTHR11496:SF57 1 361 1.2E-177 T 22-04-2016 TOLA_RS09615 82d671d8621c667ff732b898ca2b4d79 368 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 241 261 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS09615 82d671d8621c667ff732b898ca2b4d79 368 SUPERFAMILY SSF56796 3 358 6.8E-89 T 22-04-2016 TOLA_RS12100 4d19142b1575dfaf9a2df3993afb8df5 323 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 TOLA_RS12100 4d19142b1575dfaf9a2df3993afb8df5 323 PANTHER PTHR12001:SF47 2 323 1.6E-122 T 22-04-2016 TOLA_RS12100 4d19142b1575dfaf9a2df3993afb8df5 323 Pfam PF00348 Polyprenyl synthetase 31 263 7.2E-76 T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 TOLA_RS12100 4d19142b1575dfaf9a2df3993afb8df5 323 Gene3D G3DSA:1.10.600.10 7 322 2.5E-102 T 22-04-2016 IPR008949 Isoprenoid synthase domain TOLA_RS12100 4d19142b1575dfaf9a2df3993afb8df5 323 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 TOLA_RS12100 4d19142b1575dfaf9a2df3993afb8df5 323 PANTHER PTHR12001 2 323 1.6E-122 T 22-04-2016 IPR017446 Polyprenyl synthetase-related TOLA_RS12100 4d19142b1575dfaf9a2df3993afb8df5 323 SUPERFAMILY SSF48576 9 322 1.17E-99 T 22-04-2016 IPR008949 Isoprenoid synthase domain TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 Gene3D G3DSA:3.30.70.360 190 291 5.6E-35 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 Gene3D G3DSA:3.40.630.10 6 189 9.9E-73 T 22-04-2016 TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 Gene3D G3DSA:3.40.630.10 318 376 9.9E-73 T 22-04-2016 TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 SUPERFAMILY SSF53187 294 375 6.29E-65 T 22-04-2016 TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 SUPERFAMILY SSF53187 7 180 6.29E-65 T 22-04-2016 TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 SUPERFAMILY SSF55031 181 290 1.79E-28 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 PANTHER PTHR11014:SF106 6 380 3.6E-98 T 22-04-2016 TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 Pfam PF07687 Peptidase dimerisation domain 177 284 2.4E-24 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 7 375 2.4E-175 T 22-04-2016 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18|UniPathway: UPA00034 TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 Pfam PF01546 Peptidase family M20/M25/M40 64 373 3.9E-45 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 99 137 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 PANTHER PTHR11014 6 380 3.6E-98 T 22-04-2016 TOLA_RS05800 f0c987b35d86a9c4ba0f74db698a6eb0 380 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 4 377 52.7 T 22-04-2016 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18|UniPathway: UPA00034 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 Gene3D G3DSA:3.50.50.60 2 105 5.0E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 Pfam PF04324 BFD-like [2Fe-2S] binding domain 419 467 5.2E-13 T 22-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 Pfam PF04324 BFD-like [2Fe-2S] binding domain 481 529 9.4E-5 T 22-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.5E-16 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 9.5E-16 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 9.5E-16 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 9.5E-16 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 9.5E-16 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PRINTS PR00397 Sirohaem Fe-binding site signature 632 650 2.2E-6 T 22-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PRINTS PR00397 Sirohaem Fe-binding site signature 675 693 2.2E-6 T 22-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 Gene3D G3DSA:3.50.50.60 106 308 5.4E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 797 0.0 T 22-04-2016 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 UniPathway: UPA00653 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PANTHER PTHR11493:SF52 415 829 1.0E-287 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PANTHER PTHR11493:SF52 2 255 1.0E-287 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 SUPERFAMILY SSF56014 629 803 1.57E-51 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PANTHER PTHR11493 415 829 1.0E-287 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PANTHER PTHR11493 2 255 1.0E-287 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 SUPERFAMILY SSF51905 2 191 1.17E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.1E-7 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 1.1E-7 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.1E-7 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 1.1E-7 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 556 617 8.0E-10 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 628 753 3.5E-19 T 22-04-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 SUPERFAMILY SSF51905 149 309 8.52E-25 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 675 691 - T 22-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 Gene3D G3DSA:3.30.413.10 628 764 1.0E-34 T 22-04-2016 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 SUPERFAMILY SSF55124 498 637 6.21E-26 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 PIRSF PIRSF037149 1 830 0.0 T 22-04-2016 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 TOLA_RS08965 eadba3e613cb3b187eb7bf830d95cd56 839 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 285 4.1E-46 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS12830 d530c22e44a2e8554d774b9179760380 328 Gene3D G3DSA:3.30.1330.10 2 138 2.7E-43 T 22-04-2016 IPR016188 PurM-like, N-terminal domain TOLA_RS12830 d530c22e44a2e8554d774b9179760380 328 SUPERFAMILY SSF55326 2 136 9.42E-33 T 22-04-2016 TOLA_RS12830 d530c22e44a2e8554d774b9179760380 328 SUPERFAMILY SSF56042 141 305 7.03E-38 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain TOLA_RS12830 d530c22e44a2e8554d774b9179760380 328 Gene3D G3DSA:3.90.650.10 143 319 4.9E-45 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain TOLA_RS12830 d530c22e44a2e8554d774b9179760380 328 Pfam PF02769 AIR synthase related protein, C-terminal domain 148 297 5.8E-11 T 22-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain TOLA_RS12830 d530c22e44a2e8554d774b9179760380 328 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 319 2.3E-97 T 22-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 TOLA_RS12830 d530c22e44a2e8554d774b9179760380 328 Pfam PF00586 AIR synthase related protein, N-terminal domain 27 136 3.8E-23 T 22-04-2016 IPR016188 PurM-like, N-terminal domain TOLA_RS12830 d530c22e44a2e8554d774b9179760380 328 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 316 28.858 T 22-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 TOLA_RS12830 d530c22e44a2e8554d774b9179760380 328 PANTHER PTHR30270 2 326 1.2E-108 T 22-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 TOLA_RS12830 d530c22e44a2e8554d774b9179760380 328 PANTHER PTHR30270:SF0 2 326 1.2E-108 T 22-04-2016 TOLA_RS12830 d530c22e44a2e8554d774b9179760380 328 PIRSF PIRSF005303 1 319 9.6E-77 T 22-04-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 SMART SM00902 561 621 4.8E-28 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 Gene3D G3DSA:3.40.50.1780 323 453 5.2E-74 T 22-04-2016 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 Gene3D G3DSA:3.40.50.1780 212 264 5.2E-74 T 22-04-2016 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 Pfam PF02256 Iron hydrogenase small subunit 565 620 6.8E-24 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 SUPERFAMILY SSF53920 206 618 1.15E-116 T 22-04-2016 IPR009016 Iron hydrogenase TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 TIGRFAM TIGR02512 FeFe_hydrog_A: [FeFe] hydrogenase, group A 155 560 1.3E-144 T 22-04-2016 IPR013352 Iron hydrogenase, subset GO:0005506|GO:0008901|GO:0051536|GO:0055114 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 99 136 1.4E-15 T 22-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 PANTHER PTHR11615 19 488 1.2E-128 T 22-04-2016 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 PANTHER PTHR11615 508 622 1.2E-128 T 22-04-2016 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 Gene3D G3DSA:3.10.20.30 18 71 8.7E-9 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 91 4.7E-17 T 22-04-2016 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 Pfam PF02906 Iron only hydrogenase large subunit, C-terminal domain 239 556 8.2E-82 T 22-04-2016 IPR004108 Iron hydrogenase, large subunit, C-terminal TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 SUPERFAMILY SSF54292 18 89 1.48E-19 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 Gene3D G3DSA:3.30.70.20 149 211 2.5E-11 T 22-04-2016 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 SMART SM00929 99 139 1.5E-14 T 22-04-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 Pfam PF00037 4Fe-4S binding domain 205 222 5.1E-5 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 PANTHER PTHR11615:SF112 19 488 1.2E-128 T 22-04-2016 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 PANTHER PTHR11615:SF112 508 622 1.2E-128 T 22-04-2016 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 206 217 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 SUPERFAMILY SSF54862 92 229 1.38E-33 T 22-04-2016 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 47 64 - T 22-04-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 TOLA_RS07665 5cfee919d177c13121a864992d5dfbe9 623 Gene3D G3DSA:4.10.260.20 562 622 1.3E-23 T 22-04-2016 IPR003149 Iron hydrogenase, small subunit TOLA_RS13455 8de31933b5a937bec7839eacfeebdd69 444 SMART SM00928 334 379 1.2E-20 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 TOLA_RS13455 8de31933b5a937bec7839eacfeebdd69 444 SUPERFAMILY SSF142019 11 242 1.57E-84 T 22-04-2016 TOLA_RS13455 8de31933b5a937bec7839eacfeebdd69 444 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 170 185 - T 22-04-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 TOLA_RS13455 8de31933b5a937bec7839eacfeebdd69 444 SUPERFAMILY SSF142984 246 328 2.35E-21 T 22-04-2016 TOLA_RS13455 8de31933b5a937bec7839eacfeebdd69 444 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 50 222 2.7E-51 T 22-04-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain TOLA_RS13455 8de31933b5a937bec7839eacfeebdd69 444 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 337 419 1.6E-25 T 22-04-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 TOLA_RS13455 8de31933b5a937bec7839eacfeebdd69 444 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 10 421 2.0E-195 T 22-04-2016 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 TOLA_RS13455 8de31933b5a937bec7839eacfeebdd69 444 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 347 358 - T 22-04-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 TOLA_RS13455 8de31933b5a937bec7839eacfeebdd69 444 Pfam PF10531 SLBB domain 251 283 1.9E-6 T 22-04-2016 IPR019554 Soluble ligand binding domain TOLA_RS13455 8de31933b5a937bec7839eacfeebdd69 444 SUPERFAMILY SSF140490 331 423 4.32E-30 T 22-04-2016 TOLA_RS13455 8de31933b5a937bec7839eacfeebdd69 444 PANTHER PTHR11780 2 422 4.3E-211 T 22-04-2016 TOLA_RS13455 8de31933b5a937bec7839eacfeebdd69 444 PANTHER PTHR11780:SF10 2 422 4.3E-211 T 22-04-2016 TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 Gene3D G3DSA:3.40.50.970 330 535 5.4E-77 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 Gene3D G3DSA:3.40.50.970 6 323 3.6E-132 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 ProSitePatterns PS00802 Transketolase signature 2. 469 485 - T 22-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 Pfam PF02780 Transketolase, C-terminal domain 542 657 8.6E-19 T 22-04-2016 IPR033248 Transketolase, C-terminal domain TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 SMART SM00861 356 528 2.0E-65 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 SUPERFAMILY SSF52922 535 666 9.55E-41 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 PANTHER PTHR11624 1 305 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 PANTHER PTHR11624 338 666 0.0 T 22-04-2016 IPR033247 Transketolase family TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 PANTHER PTHR11624:SF1 1 305 0.0 T 22-04-2016 TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 PANTHER PTHR11624:SF1 338 666 0.0 T 22-04-2016 TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 335 1.1E-165 T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 ProSitePatterns PS00801 Transketolase signature 1. 13 33 - T 22-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 SUPERFAMILY SSF52518 6 328 5.89E-120 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 TIGRFAM TIGR00232 tktlase_bact: transketolase 7 665 0.0 T 22-04-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 Gene3D G3DSA:3.40.50.920 540 665 1.3E-46 T 22-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 SUPERFAMILY SSF52518 335 527 2.32E-65 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS15765 d1fd33b351459f9fe7c50b669507d557 666 Pfam PF02779 Transketolase, pyrimidine binding domain 356 526 1.7E-45 T 22-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 489 677 2.3E-13 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 102 366 3.3E-35 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 Gene3D G3DSA:3.40.50.1700 580 676 3.3E-14 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 Gene3D G3DSA:3.40.50.1700 476 525 1.2E-5 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 PANTHER PTHR30620:SF5 396 677 4.0E-88 T 22-04-2016 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 PANTHER PTHR30620:SF5 117 360 4.0E-88 T 22-04-2016 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 PANTHER PTHR30620:SF5 30 96 4.0E-88 T 22-04-2016 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 Gene3D G3DSA:3.20.20.300 59 467 6.9E-91 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 PANTHER PTHR30620 396 677 4.0E-88 T 22-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 PANTHER PTHR30620 117 360 4.0E-88 T 22-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 PANTHER PTHR30620 30 96 4.0E-88 T 22-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 SUPERFAMILY SSF51445 394 486 1.68E-76 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 SUPERFAMILY SSF51445 60 364 1.68E-76 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 SUPERFAMILY SSF52279 489 677 7.06E-23 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 PRINTS PR00133 Glycosyl hydrolase family 3 signature 176 195 8.2E-12 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 PRINTS PR00133 Glycosyl hydrolase family 3 signature 222 238 8.2E-12 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 PRINTS PR00133 Glycosyl hydrolase family 3 signature 344 362 8.2E-12 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS09190 e006bab43766dfba41ec724775e663df 677 PRINTS PR00133 Glycosyl hydrolase family 3 signature 260 276 8.2E-12 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS01525 920fc40c4cd5521488015ed92b378804 331 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 64 209 2.2E-12 T 22-04-2016 IPR001761 Periplasmic binding protein/LacI sugar binding domain TOLA_RS01525 920fc40c4cd5521488015ed92b378804 331 PANTHER PTHR30146:SF25 1 327 1.1E-164 T 22-04-2016 TOLA_RS01525 920fc40c4cd5521488015ed92b378804 331 SMART SM00354 1 73 8.9E-22 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS01525 920fc40c4cd5521488015ed92b378804 331 Gene3D G3DSA:3.40.50.2300 63 169 9.5E-25 T 22-04-2016 TOLA_RS01525 920fc40c4cd5521488015ed92b378804 331 SUPERFAMILY SSF53822 61 324 3.34E-37 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS01525 920fc40c4cd5521488015ed92b378804 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 50 1.0E-16 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS01525 920fc40c4cd5521488015ed92b378804 331 TIGRFAM TIGR02417 fruct_sucro_rep: D-fructose-responsive transcription factor 2 327 3.2E-128 T 22-04-2016 IPR012781 D-fructose-responsive transcription factor GO:0003677|GO:0006355|GO:0009750 TOLA_RS01525 920fc40c4cd5521488015ed92b378804 331 SUPERFAMILY SSF47413 2 58 7.5E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS01525 920fc40c4cd5521488015ed92b378804 331 Gene3D G3DSA:3.40.50.2300 170 328 6.8E-28 T 22-04-2016 TOLA_RS01525 920fc40c4cd5521488015ed92b378804 331 Gene3D G3DSA:1.10.260.40 1 62 1.0E-22 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS01525 920fc40c4cd5521488015ed92b378804 331 PANTHER PTHR30146 1 327 1.1E-164 T 22-04-2016 TOLA_RS01525 920fc40c4cd5521488015ed92b378804 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 3 21 - T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS15715 e68cbf2fe7a8720dcb2eeda9b754103b 320 SMART SM00342 229 312 3.0E-28 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS15715 e68cbf2fe7a8720dcb2eeda9b754103b 320 SUPERFAMILY SSF52317 4 194 3.06E-49 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS15715 e68cbf2fe7a8720dcb2eeda9b754103b 320 SUPERFAMILY SSF46689 213 262 3.29E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS15715 e68cbf2fe7a8720dcb2eeda9b754103b 320 Gene3D G3DSA:1.10.10.60 220 266 2.1E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS15715 e68cbf2fe7a8720dcb2eeda9b754103b 320 Pfam PF12833 Helix-turn-helix domain 235 313 1.7E-23 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS15715 e68cbf2fe7a8720dcb2eeda9b754103b 320 Gene3D G3DSA:1.10.10.60 267 315 1.1E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS15715 e68cbf2fe7a8720dcb2eeda9b754103b 320 SUPERFAMILY SSF46689 266 315 5.76E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS15715 e68cbf2fe7a8720dcb2eeda9b754103b 320 PANTHER PTHR11019:SF68 5 320 1.1E-107 T 22-04-2016 TOLA_RS15715 e68cbf2fe7a8720dcb2eeda9b754103b 320 PANTHER PTHR11019 5 320 1.1E-107 T 22-04-2016 TOLA_RS15715 e68cbf2fe7a8720dcb2eeda9b754103b 320 Pfam PF01965 DJ-1/PfpI family 5 173 9.0E-15 T 22-04-2016 IPR002818 DJ-1/PfpI TOLA_RS15715 e68cbf2fe7a8720dcb2eeda9b754103b 320 Gene3D G3DSA:3.40.50.880 5 219 1.4E-46 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS15715 e68cbf2fe7a8720dcb2eeda9b754103b 320 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 266 308 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TOLA_RS00235 cfd166c85ffbc83f4300cc4b72302d8c 103 PANTHER PTHR33755:SF2 1 90 1.8E-20 T 22-04-2016 TOLA_RS00235 cfd166c85ffbc83f4300cc4b72302d8c 103 PIRSF PIRSF029218 1 98 2.4E-22 T 22-04-2016 IPR028344 Toxin-antitoxin system, toxin component ParE1/4 TOLA_RS00235 cfd166c85ffbc83f4300cc4b72302d8c 103 PANTHER PTHR33755 1 90 1.8E-20 T 22-04-2016 TOLA_RS00235 cfd166c85ffbc83f4300cc4b72302d8c 103 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 91 5.6E-16 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 SUPERFAMILY SSF64153 20 255 7.59E-59 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 237 494 2.1E-72 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 Pfam PF03853 YjeF-related protein N-terminus 42 198 1.5E-40 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 434 444 - T 22-04-2016 IPR017953 Carbohydrate kinase, predicted, conserved site TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 21 217 1.5E-42 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 PANTHER PTHR12592:SF0 8 499 9.1E-140 T 22-04-2016 TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 Gene3D G3DSA:3.40.1190.20 243 491 3.6E-88 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 PIRSF PIRSF017184 17 500 2.1E-126 T 22-04-2016 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 Gene3D G3DSA:3.40.50.10260 20 242 4.1E-62 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 PANTHER PTHR12592 8 499 9.1E-140 T 22-04-2016 TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 SUPERFAMILY SSF53613 232 492 6.73E-74 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 Pfam PF01256 Carbohydrate kinase 257 487 1.4E-60 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 234 495 22.522 T 22-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 TOLA_RS12150 26e90cecfc77b586e7a61fa3ff920d18 510 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 21 220 22.291 T 22-04-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 PANTHER PTHR24423 597 884 2.0E-129 T 22-04-2016 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 PANTHER PTHR24423 23 198 2.0E-129 T 22-04-2016 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 SUPERFAMILY SSF47384 657 730 8.63E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 Gene3D G3DSA:3.40.50.300 22 230 6.0E-101 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 778 883 3.5E-19 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 SUPERFAMILY SSF52402 252 361 2.51E-7 T 22-04-2016 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 SMART SM00387 774 884 3.3E-26 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 23 231 1.2E-98 T 22-04-2016 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 PANTHER PTHR24423:SF562 597 884 2.0E-129 T 22-04-2016 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 PANTHER PTHR24423:SF562 23 198 2.0E-129 T 22-04-2016 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 Gene3D G3DSA:3.30.565.10 733 886 2.0E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 Gene3D G3DSA:1.20.120.620 400 504 8.9E-33 T 22-04-2016 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 Gene3D G3DSA:3.40.50.620 245 352 2.2E-7 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 SMART SM00388 663 730 1.2E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 PRINTS PR00344 Bacterial sensor protein C-terminal signature 868 881 2.7E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 PRINTS PR00344 Bacterial sensor protein C-terminal signature 844 862 2.7E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 PRINTS PR00344 Bacterial sensor protein C-terminal signature 829 839 2.7E-9 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 Gene3D G3DSA:1.10.287.130 657 726 7.3E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 SUPERFAMILY SSF55874 719 887 6.02E-36 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 Pfam PF13493 Domain of unknown function (DUF4118) 405 509 6.5E-27 T 22-04-2016 IPR025201 Sensor protein KdpD, transmembrane domain TOLA_RS06110 92ba95f37dfd671a4f88816a2578456e 897 Pfam PF00512 His Kinase A (phospho-acceptor) domain 664 729 4.9E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS04100 77f11e4812b23cc9dd8cc4580f31edcf 102 Gene3D G3DSA:3.30.300.90 1 101 9.0E-30 T 22-04-2016 IPR002634 BolA protein TOLA_RS04100 77f11e4812b23cc9dd8cc4580f31edcf 102 PANTHER PTHR12735:SF3 1 101 3.3E-32 T 22-04-2016 TOLA_RS04100 77f11e4812b23cc9dd8cc4580f31edcf 102 SUPERFAMILY SSF82657 1 86 4.19E-28 T 22-04-2016 IPR002634 BolA protein TOLA_RS04100 77f11e4812b23cc9dd8cc4580f31edcf 102 Pfam PF01722 BolA-like protein 11 85 2.6E-27 T 22-04-2016 IPR002634 BolA protein TOLA_RS04100 77f11e4812b23cc9dd8cc4580f31edcf 102 PANTHER PTHR12735 1 101 3.3E-32 T 22-04-2016 TOLA_RS04100 77f11e4812b23cc9dd8cc4580f31edcf 102 PIRSF PIRSF003113 1 101 8.2E-32 T 22-04-2016 IPR002634 BolA protein TOLA_RS02025 973c6fcbefe39f705eb096ab54361e4a 316 PANTHER PTHR37955:SF1 6 316 6.4E-54 T 22-04-2016 TOLA_RS02025 973c6fcbefe39f705eb096ab54361e4a 316 PANTHER PTHR37955 6 316 6.4E-54 T 22-04-2016 TOLA_RS02025 973c6fcbefe39f705eb096ab54361e4a 316 Pfam PF03595 Voltage-dependent anion channel 5 302 1.4E-31 T 22-04-2016 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 TOLA_RS11040 4b7255829bfedc13b08c2d89522534a7 132 SUPERFAMILY SSF54637 7 131 4.94E-38 T 22-04-2016 IPR029069 HotDog domain TOLA_RS11040 4b7255829bfedc13b08c2d89522534a7 132 PANTHER PTHR11049 1 130 4.9E-63 T 22-04-2016 TOLA_RS11040 4b7255829bfedc13b08c2d89522534a7 132 PANTHER PTHR11049:SF5 1 130 4.9E-63 T 22-04-2016 TOLA_RS11040 4b7255829bfedc13b08c2d89522534a7 132 Pfam PF03061 Thioesterase superfamily 26 98 4.8E-21 T 22-04-2016 IPR006683 Thioesterase domain TOLA_RS11040 4b7255829bfedc13b08c2d89522534a7 132 Gene3D G3DSA:3.10.129.10 3 131 4.0E-40 T 22-04-2016 IPR029069 HotDog domain TOLA_RS04935 1f5a983c20baa31cebdafcdf8c7532ab 235 PANTHER PTHR23417 1 234 4.4E-87 T 22-04-2016 TOLA_RS04935 1f5a983c20baa31cebdafcdf8c7532ab 235 Pfam PF02390 Putative methyltransferase 61 229 3.0E-60 T 22-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 TOLA_RS04935 1f5a983c20baa31cebdafcdf8c7532ab 235 SUPERFAMILY SSF53335 13 232 2.17E-40 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04935 1f5a983c20baa31cebdafcdf8c7532ab 235 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 21 234 30.948 T 22-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 TOLA_RS04935 1f5a983c20baa31cebdafcdf8c7532ab 235 PANTHER PTHR23417:SF14 1 234 4.4E-87 T 22-04-2016 TOLA_RS04935 1f5a983c20baa31cebdafcdf8c7532ab 235 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 47 233 7.6E-66 T 22-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 TOLA_RS04935 1f5a983c20baa31cebdafcdf8c7532ab 235 Gene3D G3DSA:3.40.50.150 37 190 1.5E-17 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS05090 15fdfd231b1be90114c3c47899387209 268 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 133 243 2.8E-22 T 22-04-2016 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05090 15fdfd231b1be90114c3c47899387209 268 SUPERFAMILY SSF51735 1 158 2.49E-20 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS05090 15fdfd231b1be90114c3c47899387209 268 PIRSF PIRSF000161 1 245 2.1E-43 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05090 15fdfd231b1be90114c3c47899387209 268 Gene3D G3DSA:3.40.50.720 1 139 9.6E-16 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS05090 15fdfd231b1be90114c3c47899387209 268 SUPERFAMILY SSF55347 132 215 6.76E-10 T 22-04-2016 TOLA_RS05090 15fdfd231b1be90114c3c47899387209 268 Gene3D G3DSA:3.30.360.10 140 212 5.5E-16 T 22-04-2016 TOLA_RS05090 15fdfd231b1be90114c3c47899387209 268 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 128 4.6E-15 T 22-04-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05090 15fdfd231b1be90114c3c47899387209 268 PANTHER PTHR20836 65 251 1.2E-31 T 22-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS00055 4e737dcd855ea915b60d0c01e8e095b4 309 Gene3D G3DSA:1.20.58.340 235 309 7.8E-17 T 22-04-2016 TOLA_RS00055 4e737dcd855ea915b60d0c01e8e095b4 309 Gene3D G3DSA:1.20.58.340 131 225 3.3E-15 T 22-04-2016 TOLA_RS00055 4e737dcd855ea915b60d0c01e8e095b4 309 Pfam PF01544 CorA-like Mg2+ transporter protein 23 307 2.0E-62 T 22-04-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 TOLA_RS00055 4e737dcd855ea915b60d0c01e8e095b4 309 SUPERFAMILY SSF144083 245 306 7.85E-13 T 22-04-2016 TOLA_RS00055 4e737dcd855ea915b60d0c01e8e095b4 309 SUPERFAMILY SSF143865 13 241 7.85E-45 T 22-04-2016 TOLA_RS00055 4e737dcd855ea915b60d0c01e8e095b4 309 PANTHER PTHR21535 20 309 1.7E-37 T 22-04-2016 TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 Gene3D G3DSA:2.20.28.10 414 463 1.5E-18 T 22-04-2016 IPR004039 Rubredoxin-type fold TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 Pfam PF00258 Flavodoxin 255 384 4.9E-8 T 22-04-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 SMART SM00849 34 210 8.6E-26 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 Pfam PF00753 Metallo-beta-lactamase superfamily 34 168 2.1E-9 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 SUPERFAMILY SSF52218 250 394 6.13E-35 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 Gene3D G3DSA:3.60.15.10 3 245 1.5E-90 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 SUPERFAMILY SSF57802 412 464 1.85E-16 T 22-04-2016 TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 PANTHER PTHR32145:SF2 1 458 7.3E-185 T 22-04-2016 TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 PANTHER PTHR32145 1 458 7.3E-185 T 22-04-2016 TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 PIRSF PIRSF005243 1 397 1.0E-156 T 22-04-2016 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 Pfam PF00301 Rubredoxin 415 460 2.5E-16 T 22-04-2016 IPR024935 Rubredoxin domain GO:0005506 TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 Gene3D G3DSA:3.40.50.360 248 392 1.2E-49 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS09265 e4ef4cb3cd93d875564e13f33a702c1b 471 SUPERFAMILY SSF56281 8 284 3.11E-51 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS10740 25bb22eade28dabcca6b4200035017f5 263 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 168 186 - T 22-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 TOLA_RS10740 25bb22eade28dabcca6b4200035017f5 263 PANTHER PTHR10804:SF75 1 260 5.5E-176 T 22-04-2016 TOLA_RS10740 25bb22eade28dabcca6b4200035017f5 263 Hamap MF_01974 Methionine aminopeptidase [map]. 3 251 42.335 T 22-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 TOLA_RS10740 25bb22eade28dabcca6b4200035017f5 263 Gene3D G3DSA:3.90.230.10 3 255 1.2E-103 T 22-04-2016 IPR000994 Peptidase M24, structural domain TOLA_RS10740 25bb22eade28dabcca6b4200035017f5 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 92 108 1.8E-21 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase TOLA_RS10740 25bb22eade28dabcca6b4200035017f5 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 69 82 1.8E-21 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase TOLA_RS10740 25bb22eade28dabcca6b4200035017f5 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 162 174 1.8E-21 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase TOLA_RS10740 25bb22eade28dabcca6b4200035017f5 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 193 205 1.8E-21 T 22-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase TOLA_RS10740 25bb22eade28dabcca6b4200035017f5 263 SUPERFAMILY SSF55920 3 254 1.57E-95 T 22-04-2016 IPR000994 Peptidase M24, structural domain TOLA_RS10740 25bb22eade28dabcca6b4200035017f5 263 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 250 6.5E-104 T 22-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 TOLA_RS10740 25bb22eade28dabcca6b4200035017f5 263 PANTHER PTHR10804 1 260 5.5E-176 T 22-04-2016 TOLA_RS10740 25bb22eade28dabcca6b4200035017f5 263 Pfam PF00557 Metallopeptidase family M24 12 242 6.6E-54 T 22-04-2016 IPR000994 Peptidase M24, structural domain TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 PANTHER PTHR24423:SF544 378 868 1.9E-126 T 22-04-2016 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 PANTHER PTHR24423:SF544 7 13 1.9E-126 T 22-04-2016 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 Gene3D G3DSA:3.30.565.10 573 731 9.5E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 PANTHER PTHR24423 378 868 1.9E-126 T 22-04-2016 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 PANTHER PTHR24423 7 13 1.9E-126 T 22-04-2016 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 PRINTS PR00344 Bacterial sensor protein C-terminal signature 661 675 8.2E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 PRINTS PR00344 Bacterial sensor protein C-terminal signature 679 689 8.2E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 PRINTS PR00344 Bacterial sensor protein C-terminal signature 692 710 8.2E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 PRINTS PR00344 Bacterial sensor protein C-terminal signature 716 729 8.2E-14 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 SMART SM00304 317 370 1.0E-5 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 SMART SM00388 506 573 2.1E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 Gene3D G3DSA:3.30.450.20 378 491 1.9E-5 T 22-04-2016 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 SMART SM00387 614 732 2.2E-27 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 SUPERFAMILY SSF47384 501 571 3.92E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 Pfam PF00072 Response regulator receiver domain 756 860 1.1E-7 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 SMART SM00448 754 863 2.1E-4 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 Gene3D G3DSA:1.10.287.130 502 569 6.1E-6 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 SUPERFAMILY SSF158472 325 366 1.24E-7 T 22-04-2016 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 SUPERFAMILY SSF52172 753 869 1.99E-15 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 SUPERFAMILY SSF55874 564 733 6.42E-37 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 Pfam PF00672 HAMP domain 300 365 7.9E-8 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 615 729 2.2E-21 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 Gene3D G3DSA:3.40.50.2300 752 870 8.8E-18 T 22-04-2016 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 Pfam PF12860 PAS fold 388 492 1.3E-6 T 22-04-2016 TOLA_RS00305 64b62a43a85c9eada6314ca009982a10 872 Pfam PF00512 His Kinase A (phospho-acceptor) domain 508 572 8.9E-11 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS02685 f0d91482522a7e0a4feebb0f588bfeee 103 Hamap MF_00910 Cell division protein FtsL [ftsL]. 17 100 14.77 T 22-04-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 TOLA_RS02685 f0d91482522a7e0a4feebb0f588bfeee 103 PANTHER PTHR37479 1 103 9.5E-18 T 22-04-2016 TOLA_RS02685 f0d91482522a7e0a4feebb0f588bfeee 103 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 24 100 1.7E-17 T 22-04-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 TOLA_RS02685 f0d91482522a7e0a4feebb0f588bfeee 103 PANTHER PTHR37479:SF1 1 103 9.5E-18 T 22-04-2016 TOLA_RS02685 f0d91482522a7e0a4feebb0f588bfeee 103 Pfam PF04999 Cell division protein FtsL 9 101 1.7E-23 T 22-04-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 TOLA_RS10645 a0f19f5dcc54c3e14e184c400d13c889 258 Pfam PF01875 Memo-like protein 6 254 1.6E-46 T 22-04-2016 IPR002737 MEMO1 family TOLA_RS10645 a0f19f5dcc54c3e14e184c400d13c889 258 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 6 256 1.6E-77 T 22-04-2016 IPR002737 MEMO1 family TOLA_RS10645 a0f19f5dcc54c3e14e184c400d13c889 258 Hamap MF_00055 MEMO1 family protein . 3 258 51.477 T 22-04-2016 IPR002737 MEMO1 family TOLA_RS10645 a0f19f5dcc54c3e14e184c400d13c889 258 PANTHER PTHR11060:SF0 1 202 6.1E-35 T 22-04-2016 TOLA_RS10645 a0f19f5dcc54c3e14e184c400d13c889 258 PANTHER PTHR11060 1 202 6.1E-35 T 22-04-2016 IPR002737 MEMO1 family TOLA_RS14540 7d4a26fccae89e0871b249352a0b837b 227 Pfam PF02698 DUF218 domain 62 182 8.0E-16 T 22-04-2016 IPR003848 Domain of unknown function DUF218 TOLA_RS14540 7d4a26fccae89e0871b249352a0b837b 227 PANTHER PTHR30336 4 227 2.9E-71 T 22-04-2016 TOLA_RS14540 7d4a26fccae89e0871b249352a0b837b 227 PANTHER PTHR30336:SF0 4 227 2.9E-71 T 22-04-2016 TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 PANTHER PTHR10925 43 663 7.1E-104 T 22-04-2016 IPR032672 TmcA/NAT10/Kre33 GO:0008080 TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 SUPERFAMILY SSF52540 169 291 8.28E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 Pfam PF08351 Domain of unknown function (DUF1726) 59 147 2.5E-17 T 22-04-2016 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 Pfam PF13718 GNAT acetyltransferase 2 503 550 1.7E-6 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 Pfam PF13718 GNAT acetyltransferase 2 385 500 1.8E-16 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 Gene3D G3DSA:3.40.50.300 177 291 8.6E-7 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 Pfam PF17176 tRNA-binding domain 562 681 4.6E-9 T 22-04-2016 IPR033442 tRNA(Met) cytidine acetyltransferase TmcA, tRNA-binding domain KEGG: 00650+2.3.1.19 TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 Gene3D G3DSA:3.40.630.30 378 432 6.7E-6 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 Gene3D G3DSA:3.40.630.30 470 529 6.7E-6 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 Pfam PF05127 Helicase 202 352 4.1E-45 T 22-04-2016 IPR007807 Helicase domain TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 16 683 50.126 T 22-04-2016 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 KEGG: 00650+2.3.1.19 TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 PANTHER PTHR10925:SF6 43 663 7.1E-104 T 22-04-2016 TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 SUPERFAMILY SSF55729 470 530 1.71E-8 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS15505 af27b6ebb65c28b41a57db1f5afd922f 691 SUPERFAMILY SSF55729 377 434 1.71E-8 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS01350 8e12bb8da6ac31a6db4405039b513534 163 PIRSF PIRSF018472 5 163 5.0E-49 T 22-04-2016 IPR026034 Cell shape-determining protein MreD, proteobacterial type TOLA_RS01350 8e12bb8da6ac31a6db4405039b513534 163 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 13 154 6.2E-35 T 22-04-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 TOLA_RS01350 8e12bb8da6ac31a6db4405039b513534 163 PANTHER PTHR37484 1 163 3.7E-53 T 22-04-2016 TOLA_RS01350 8e12bb8da6ac31a6db4405039b513534 163 Pfam PF04093 rod shape-determining protein MreD 14 155 2.1E-28 T 22-04-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 TOLA_RS16160 120e4c4f4ba8f1ac2b22bfca5c860631 303 Pfam PF03466 LysR substrate binding domain 91 293 1.3E-44 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS16160 120e4c4f4ba8f1ac2b22bfca5c860631 303 PANTHER PTHR30537 1 294 1.5E-119 T 22-04-2016 TOLA_RS16160 120e4c4f4ba8f1ac2b22bfca5c860631 303 Gene3D G3DSA:1.10.10.10 3 80 3.5E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS16160 120e4c4f4ba8f1ac2b22bfca5c860631 303 Gene3D G3DSA:3.40.190.10 177 261 5.1E-23 T 22-04-2016 TOLA_RS16160 120e4c4f4ba8f1ac2b22bfca5c860631 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.2E-19 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS16160 120e4c4f4ba8f1ac2b22bfca5c860631 303 Gene3D G3DSA:3.40.190.10 92 176 8.2E-26 T 22-04-2016 TOLA_RS16160 120e4c4f4ba8f1ac2b22bfca5c860631 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.2E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS16160 120e4c4f4ba8f1ac2b22bfca5c860631 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.2E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS16160 120e4c4f4ba8f1ac2b22bfca5c860631 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.2E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS16160 120e4c4f4ba8f1ac2b22bfca5c860631 303 SUPERFAMILY SSF53850 92 296 9.23E-50 T 22-04-2016 TOLA_RS16160 120e4c4f4ba8f1ac2b22bfca5c860631 303 SUPERFAMILY SSF46785 4 84 1.6E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS16160 120e4c4f4ba8f1ac2b22bfca5c860631 303 PANTHER PTHR30537:SF5 1 294 1.5E-119 T 22-04-2016 TOLA_RS05405 6e3c798584f49d02e67ef708c54d6346 240 PANTHER PTHR21098 1 236 1.9E-80 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS05405 6e3c798584f49d02e67ef708c54d6346 240 Gene3D G3DSA:2.40.30.20 5 105 1.8E-25 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS05405 6e3c798584f49d02e67ef708c54d6346 240 PANTHER PTHR21098:SF4 1 236 1.9E-80 T 22-04-2016 TOLA_RS05405 6e3c798584f49d02e67ef708c54d6346 240 Gene3D G3DSA:2.40.30.20 106 197 2.2E-22 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS05405 6e3c798584f49d02e67ef708c54d6346 240 SUPERFAMILY SSF63380 94 201 6.55E-27 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TOLA_RS05405 6e3c798584f49d02e67ef708c54d6346 240 Pfam PF00677 Lumazine binding domain 3 88 1.3E-17 T 22-04-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS05405 6e3c798584f49d02e67ef708c54d6346 240 Pfam PF00677 Lumazine binding domain 101 186 3.1E-16 T 22-04-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS05405 6e3c798584f49d02e67ef708c54d6346 240 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 204 2.4E-56 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS05405 6e3c798584f49d02e67ef708c54d6346 240 PIRSF PIRSF000498 1 209 2.2E-57 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS05405 6e3c798584f49d02e67ef708c54d6346 240 SUPERFAMILY SSF63380 1 89 7.82E-22 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TOLA_RS12730 4227f1262779a4e36f5b86c59f91fc94 213 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 44 198 3.2E-63 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 TOLA_RS12730 4227f1262779a4e36f5b86c59f91fc94 213 PANTHER PTHR10173:SF36 1 205 1.1E-92 T 22-04-2016 TOLA_RS12730 4227f1262779a4e36f5b86c59f91fc94 213 PANTHER PTHR10173 1 205 1.1E-92 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 TOLA_RS12730 4227f1262779a4e36f5b86c59f91fc94 213 Gene3D G3DSA:3.30.1060.10 4 198 7.9E-76 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 TOLA_RS12730 4227f1262779a4e36f5b86c59f91fc94 213 SUPERFAMILY SSF55068 4 206 5.89E-77 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 TOLA_RS12730 4227f1262779a4e36f5b86c59f91fc94 213 Pfam PF01625 Peptide methionine sulfoxide reductase 45 198 1.8E-63 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 TOLA_RS12730 4227f1262779a4e36f5b86c59f91fc94 213 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 42 204 37.521 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 Pfam PF16582 Middle domain of thiamine pyrophosphate 194 399 5.8E-63 T 22-04-2016 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 15 443 4.4E-136 T 22-04-2016 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 9 568 33.559 T 22-04-2016 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 417 550 7.6E-9 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 SUPERFAMILY SSF52518 11 186 3.32E-36 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 PANTHER PTHR18968:SF114 1 569 1.6E-181 T 22-04-2016 TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 Gene3D G3DSA:3.40.50.970 402 556 2.1E-22 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 16 185 8.0E-33 T 22-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 Gene3D G3DSA:3.40.50.970 15 188 1.4E-47 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 PIRSF PIRSF004983 7 572 1.6E-169 T 22-04-2016 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 SUPERFAMILY SSF52518 391 564 2.36E-25 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 SUPERFAMILY SSF52467 229 349 1.87E-5 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain TOLA_RS02260 4062fa3f1543408ff7fcaea7a69a377a 573 PANTHER PTHR18968 1 569 1.6E-181 T 22-04-2016 TOLA_RS05490 4210f26764076658cf50936af866ee0b 235 Gene3D G3DSA:3.30.420.40 1 128 1.2E-42 T 22-04-2016 TOLA_RS05490 4210f26764076658cf50936af866ee0b 235 SUPERFAMILY SSF53067 109 221 6.09E-16 T 22-04-2016 TOLA_RS05490 4210f26764076658cf50936af866ee0b 235 SUPERFAMILY SSF53067 2 103 2.55E-29 T 22-04-2016 TOLA_RS05490 4210f26764076658cf50936af866ee0b 235 PANTHER PTHR11735 1 139 1.0E-49 T 22-04-2016 TOLA_RS05490 4210f26764076658cf50936af866ee0b 235 Pfam PF00814 Glycoprotease family 29 148 2.5E-29 T 22-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TOLA_RS05490 4210f26764076658cf50936af866ee0b 235 PANTHER PTHR11735:SF11 1 139 1.0E-49 T 22-04-2016 TOLA_RS05490 4210f26764076658cf50936af866ee0b 235 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 223 7.0E-59 T 22-04-2016 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 TOLA_RS01475 f927f6617bbf314ddedddfe2b5869030 292 PANTHER PTHR30126 1 292 9.1E-125 T 22-04-2016 TOLA_RS01475 f927f6617bbf314ddedddfe2b5869030 292 Gene3D G3DSA:1.10.10.10 1 81 2.5E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01475 f927f6617bbf314ddedddfe2b5869030 292 SUPERFAMILY SSF46785 1 111 2.85E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01475 f927f6617bbf314ddedddfe2b5869030 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.6E-15 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS01475 f927f6617bbf314ddedddfe2b5869030 292 SUPERFAMILY SSF53850 89 292 1.43E-33 T 22-04-2016 TOLA_RS01475 f927f6617bbf314ddedddfe2b5869030 292 Pfam PF03466 LysR substrate binding domain 87 291 1.5E-36 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS01475 f927f6617bbf314ddedddfe2b5869030 292 PANTHER PTHR30126:SF14 1 292 9.1E-125 T 22-04-2016 TOLA_RS01475 f927f6617bbf314ddedddfe2b5869030 292 Gene3D G3DSA:3.40.190.10 199 258 1.0E-11 T 22-04-2016 TOLA_RS01475 f927f6617bbf314ddedddfe2b5869030 292 Gene3D G3DSA:3.40.190.10 82 198 1.3E-22 T 22-04-2016 TOLA_RS00245 46b34d5099f38eaf89264fc46554d445 706 PANTHER PTHR32438 77 564 2.2E-211 T 22-04-2016 TOLA_RS00245 46b34d5099f38eaf89264fc46554d445 706 PANTHER PTHR32438 583 692 2.2E-211 T 22-04-2016 TOLA_RS00245 46b34d5099f38eaf89264fc46554d445 706 Pfam PF02446 4-alpha-glucanotransferase 147 669 3.7E-135 T 22-04-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TOLA_RS00245 46b34d5099f38eaf89264fc46554d445 706 PANTHER PTHR32438:SF5 77 564 2.2E-211 T 22-04-2016 TOLA_RS00245 46b34d5099f38eaf89264fc46554d445 706 PANTHER PTHR32438:SF5 583 692 2.2E-211 T 22-04-2016 TOLA_RS00245 46b34d5099f38eaf89264fc46554d445 706 Gene3D G3DSA:3.20.20.80 139 576 1.9E-165 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS00245 46b34d5099f38eaf89264fc46554d445 706 Gene3D G3DSA:3.20.20.80 615 690 1.9E-165 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS00245 46b34d5099f38eaf89264fc46554d445 706 SUPERFAMILY SSF51445 126 563 6.0E-153 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS00245 46b34d5099f38eaf89264fc46554d445 706 SUPERFAMILY SSF51445 602 691 6.0E-153 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS00245 46b34d5099f38eaf89264fc46554d445 706 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 98 689 1.1E-219 T 22-04-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TOLA_RS00445 36bbddf92e8f734d317eda27b6fb436e 199 Pfam PF03358 NADPH-dependent FMN reductase 3 143 6.4E-11 T 22-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TOLA_RS00445 36bbddf92e8f734d317eda27b6fb436e 199 SUPERFAMILY SSF52218 1 198 1.44E-58 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS00445 36bbddf92e8f734d317eda27b6fb436e 199 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 2 197 6.8E-92 T 22-04-2016 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 TOLA_RS00445 36bbddf92e8f734d317eda27b6fb436e 199 PANTHER PTHR30546 1 198 4.4E-122 T 22-04-2016 TOLA_RS00445 36bbddf92e8f734d317eda27b6fb436e 199 Hamap MF_01017 NAD(P)H dehydrogenase (quinone). 1 199 39.664 T 22-04-2016 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 TOLA_RS00445 36bbddf92e8f734d317eda27b6fb436e 199 Gene3D G3DSA:3.40.50.360 1 199 1.2E-71 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS00445 36bbddf92e8f734d317eda27b6fb436e 199 PANTHER PTHR30546:SF10 1 198 4.4E-122 T 22-04-2016 TOLA_RS04440 5cb5bee99d1bf7b72f642dd31788cffb 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 296 6.6E-21 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04440 5cb5bee99d1bf7b72f642dd31788cffb 297 PANTHER PTHR30465 8 297 2.0E-127 T 22-04-2016 TOLA_RS04440 5cb5bee99d1bf7b72f642dd31788cffb 297 Gene3D G3DSA:1.10.3720.10 87 293 3.6E-21 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04440 5cb5bee99d1bf7b72f642dd31788cffb 297 SUPERFAMILY SSF161098 91 277 6.54E-24 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04440 5cb5bee99d1bf7b72f642dd31788cffb 297 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 15 67 4.0E-12 T 22-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TOLA_RS04440 5cb5bee99d1bf7b72f642dd31788cffb 297 PANTHER PTHR30465:SF49 8 297 2.0E-127 T 22-04-2016 TOLA_RS04520 609f0c8dad0883b4dd2f3bdd2028d054 760 PANTHER PTHR30191 11 760 0.0 T 22-04-2016 TOLA_RS04520 609f0c8dad0883b4dd2f3bdd2028d054 760 PIRSF PIRSF000379 8 760 0.0 T 22-04-2016 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493|UniPathway: UPA00920 TOLA_RS04520 609f0c8dad0883b4dd2f3bdd2028d054 760 Pfam PF01228 Glycine radical 630 741 1.8E-42 T 22-04-2016 IPR001150 Glycine radical domain GO:0003824|GO:0008152 TOLA_RS04520 609f0c8dad0883b4dd2f3bdd2028d054 760 Pfam PF02901 Pyruvate formate lyase-like 26 614 1.8E-202 T 22-04-2016 IPR004184 Pyruvate formate lyase domain GO:0003824 TOLA_RS04520 609f0c8dad0883b4dd2f3bdd2028d054 760 SUPERFAMILY SSF51998 5 759 3.97E-287 T 22-04-2016 TOLA_RS04520 609f0c8dad0883b4dd2f3bdd2028d054 760 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 11 760 0.0 T 22-04-2016 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493|UniPathway: UPA00920 TOLA_RS04520 609f0c8dad0883b4dd2f3bdd2028d054 760 ProSitePatterns PS00850 Glycine radical domain signature. 730 738 - T 22-04-2016 IPR019777 Formate C-acetyltransferase glycine radical, conserved site TOLA_RS04520 609f0c8dad0883b4dd2f3bdd2028d054 760 Gene3D G3DSA:3.20.70.20 6 760 0.0 T 22-04-2016 TOLA_RS04520 609f0c8dad0883b4dd2f3bdd2028d054 760 PANTHER PTHR30191:SF7 11 760 0.0 T 22-04-2016 TOLA_RS08635 a81dbb09088fe0ac56cb033c558fca66 371 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 362 3.1E-104 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 TOLA_RS08635 a81dbb09088fe0ac56cb033c558fca66 371 PANTHER PTHR11496 1 371 1.6E-172 T 22-04-2016 TOLA_RS08635 a81dbb09088fe0ac56cb033c558fca66 371 SUPERFAMILY SSF56796 4 369 1.31E-102 T 22-04-2016 TOLA_RS08635 a81dbb09088fe0ac56cb033c558fca66 371 PANTHER PTHR11496:SF71 1 371 1.6E-172 T 22-04-2016 TOLA_RS08635 a81dbb09088fe0ac56cb033c558fca66 371 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 154 182 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS08635 a81dbb09088fe0ac56cb033c558fca66 371 Gene3D G3DSA:1.20.1090.10 166 370 4.0E-63 T 22-04-2016 TOLA_RS08635 a81dbb09088fe0ac56cb033c558fca66 371 Gene3D G3DSA:3.40.50.1970 2 165 4.2E-45 T 22-04-2016 TOLA_RS08995 85e4d9d7e7bce9351b03a535f039a886 276 Pfam PF00005 ABC transporter 27 166 1.8E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS08995 85e4d9d7e7bce9351b03a535f039a886 276 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS08995 85e4d9d7e7bce9351b03a535f039a886 276 PANTHER PTHR24220 7 254 3.1E-116 T 22-04-2016 TOLA_RS08995 85e4d9d7e7bce9351b03a535f039a886 276 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 26 254 6.7E-107 T 22-04-2016 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 TOLA_RS08995 85e4d9d7e7bce9351b03a535f039a886 276 PANTHER PTHR24220:SF361 7 254 3.1E-116 T 22-04-2016 TOLA_RS08995 85e4d9d7e7bce9351b03a535f039a886 276 Gene3D G3DSA:3.40.50.300 2 219 4.1E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08995 85e4d9d7e7bce9351b03a535f039a886 276 SMART SM00382 34 216 4.8E-19 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS08995 85e4d9d7e7bce9351b03a535f039a886 276 SUPERFAMILY SSF52540 11 231 8.76E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10880 c037afd1b94f0b621f84ac3010431344 335 Gene3D G3DSA:3.40.50.2300 64 168 3.2E-28 T 22-04-2016 TOLA_RS10880 c037afd1b94f0b621f84ac3010431344 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.3E-6 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS10880 c037afd1b94f0b621f84ac3010431344 335 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.3E-6 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS10880 c037afd1b94f0b621f84ac3010431344 335 SUPERFAMILY SSF47413 1 49 1.44E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS10880 c037afd1b94f0b621f84ac3010431344 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 46 1.2E-17 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS10880 c037afd1b94f0b621f84ac3010431344 335 SMART SM00354 1 73 8.6E-17 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS10880 c037afd1b94f0b621f84ac3010431344 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS10880 c037afd1b94f0b621f84ac3010431344 335 PANTHER PTHR30146 1 327 8.2E-85 T 22-04-2016 TOLA_RS10880 c037afd1b94f0b621f84ac3010431344 335 Gene3D G3DSA:3.40.50.2300 169 327 1.6E-38 T 22-04-2016 TOLA_RS10880 c037afd1b94f0b621f84ac3010431344 335 Gene3D G3DSA:1.10.260.40 1 46 2.9E-21 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS10880 c037afd1b94f0b621f84ac3010431344 335 Pfam PF13377 Periplasmic binding protein-like domain 168 327 1.0E-29 T 22-04-2016 TOLA_RS10880 c037afd1b94f0b621f84ac3010431344 335 SUPERFAMILY SSF53822 65 327 3.73E-53 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS04305 25eac3a5f04285361ae88296f3c79a42 483 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 2 481 8.2E-216 T 22-04-2016 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS04305 25eac3a5f04285361ae88296f3c79a42 483 Pfam PF02378 Phosphotransferase system, EIIC 12 323 6.5E-82 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS04305 25eac3a5f04285361ae88296f3c79a42 483 SUPERFAMILY SSF55604 407 479 1.7E-19 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS04305 25eac3a5f04285361ae88296f3c79a42 483 PANTHER PTHR30009:SF2 5 480 1.0E-240 T 22-04-2016 TOLA_RS04305 25eac3a5f04285361ae88296f3c79a42 483 Pfam PF00367 phosphotransferase system, EIIB 410 442 2.6E-12 T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS04305 25eac3a5f04285361ae88296f3c79a42 483 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 385 466 4.4E-20 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS04305 25eac3a5f04285361ae88296f3c79a42 483 PANTHER PTHR30009 5 480 1.0E-240 T 22-04-2016 TOLA_RS04305 25eac3a5f04285361ae88296f3c79a42 483 Gene3D G3DSA:3.30.1360.60 405 481 6.7E-26 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS15740 8654c3a58fcf2c06e4a98e122e54c3e4 588 Gene3D G3DSA:3.40.50.270 493 583 7.2E-17 T 22-04-2016 TOLA_RS15740 8654c3a58fcf2c06e4a98e122e54c3e4 588 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 494 567 1.1E-11 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS15740 8654c3a58fcf2c06e4a98e122e54c3e4 588 PANTHER PTHR33843:SF5 2 465 1.0E-289 T 22-04-2016 TOLA_RS15740 8654c3a58fcf2c06e4a98e122e54c3e4 588 PANTHER PTHR33843 2 465 1.0E-289 T 22-04-2016 TOLA_RS15740 8654c3a58fcf2c06e4a98e122e54c3e4 588 PIRSF PIRSF037343 1 586 4.7E-283 T 22-04-2016 IPR017180 Phosphotransferase system component IIBC, sugar-specific, predicted TOLA_RS15740 8654c3a58fcf2c06e4a98e122e54c3e4 588 Pfam PF03611 PTS system sugar-specific permease component 15 415 2.8E-121 T 22-04-2016 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 TOLA_RS15740 8654c3a58fcf2c06e4a98e122e54c3e4 588 SUPERFAMILY SSF52794 492 583 1.99E-14 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS07545 3462b67988f30bd02380ba5daf17c21c 192 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 21 164 4.0E-14 T 22-04-2016 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family TOLA_RS07545 3462b67988f30bd02380ba5daf17c21c 192 Gene3D G3DSA:2.30.30.330 19 185 3.1E-30 T 22-04-2016 TOLA_RS07545 3462b67988f30bd02380ba5daf17c21c 192 SUPERFAMILY SSF54001 20 186 3.63E-28 T 22-04-2016 TOLA_RS10660 be69057cbfa2415800e551c1df1bc941 1160 Gene3D G3DSA:1.10.150.280 836 881 5.2E-7 T 22-04-2016 TOLA_RS10660 be69057cbfa2415800e551c1df1bc941 1160 Pfam PF02811 PHP domain 8 172 1.2E-40 T 22-04-2016 IPR004013 PHP domain GO:0003824 TOLA_RS10660 be69057cbfa2415800e551c1df1bc941 1160 Gene3D G3DSA:3.20.20.140 6 263 6.7E-23 T 22-04-2016 TOLA_RS10660 be69057cbfa2415800e551c1df1bc941 1160 PANTHER PTHR32294:SF0 2 1160 0.0 T 22-04-2016 TOLA_RS10660 be69057cbfa2415800e551c1df1bc941 1160 SUPERFAMILY SSF89550 6 263 1.84E-18 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 TOLA_RS10660 be69057cbfa2415800e551c1df1bc941 1160 PANTHER PTHR32294 2 1160 0.0 T 22-04-2016 TOLA_RS10660 be69057cbfa2415800e551c1df1bc941 1160 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 292 735 4.2E-175 T 22-04-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS10660 be69057cbfa2415800e551c1df1bc941 1160 Gene3D G3DSA:2.40.50.140 989 1077 2.7E-8 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS10660 be69057cbfa2415800e551c1df1bc941 1160 Pfam PF14579 Helix-hairpin-helix motif 808 897 9.1E-27 T 22-04-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS10660 be69057cbfa2415800e551c1df1bc941 1160 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1031 0.0 T 22-04-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS10660 be69057cbfa2415800e551c1df1bc941 1160 SMART SM00481 7 74 3.7E-23 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 TOLA_RS10660 be69057cbfa2415800e551c1df1bc941 1160 Pfam PF01336 OB-fold nucleic acid binding domain 999 1070 1.4E-7 T 22-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TOLA_RS02540 9a2d71a1fe3a308371d14bd09e90c938 260 SMART SM00475 2 257 4.3E-58 T 22-04-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 TOLA_RS02540 9a2d71a1fe3a308371d14bd09e90c938 260 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 3 167 1.4E-27 T 22-04-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 TOLA_RS02540 9a2d71a1fe3a308371d14bd09e90c938 260 Hamap MF_01192 Flap endonuclease Xni [xni]. 1 258 39.901 T 22-04-2016 IPR022895 Flap endonuclease Xni GO:0048256 TOLA_RS02540 9a2d71a1fe3a308371d14bd09e90c938 260 SUPERFAMILY SSF47807 167 259 4.04E-19 T 22-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 TOLA_RS02540 9a2d71a1fe3a308371d14bd09e90c938 260 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 169 259 4.0E-23 T 22-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 TOLA_RS02540 9a2d71a1fe3a308371d14bd09e90c938 260 PANTHER PTHR10133 2 256 1.1E-83 T 22-04-2016 TOLA_RS02540 9a2d71a1fe3a308371d14bd09e90c938 260 PANTHER PTHR10133:SF39 2 256 1.1E-83 T 22-04-2016 TOLA_RS02540 9a2d71a1fe3a308371d14bd09e90c938 260 SMART SM00279 170 205 5.2E-12 T 22-04-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TOLA_RS02540 9a2d71a1fe3a308371d14bd09e90c938 260 Gene3D G3DSA:1.10.150.20 183 242 4.2E-17 T 22-04-2016 TOLA_RS02540 9a2d71a1fe3a308371d14bd09e90c938 260 Gene3D G3DSA:3.40.50.1010 3 182 5.0E-42 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS02540 9a2d71a1fe3a308371d14bd09e90c938 260 SUPERFAMILY SSF88723 2 167 1.21E-34 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 Gene3D G3DSA:3.40.50.1380 5 190 6.2E-86 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 8 530 1.2E-256 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 Pfam PF01808 AICARFT/IMPCHase bienzyme 137 461 6.0E-119 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 530 45.786 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 PANTHER PTHR11692:SF2 5 530 0.0 T 22-04-2016 TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 Pfam PF02142 MGS-like domain 19 132 7.8E-29 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 SUPERFAMILY SSF53927 222 530 1.7E-131 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 SMART SM00851 19 132 3.8E-62 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 PIRSF PIRSF000414 1 530 4.0E-228 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 Gene3D G3DSA:3.40.140.20 378 520 6.6E-62 T 22-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 SUPERFAMILY SSF52335 7 196 2.62E-71 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 Gene3D G3DSA:3.40.140.20 254 372 1.4E-49 T 22-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 SMART SM00798 137 462 6.4E-219 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 TOLA_RS02795 02fa1c980682d29fa4d45a8df434c29f 530 PANTHER PTHR11692 5 530 0.0 T 22-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 TOLA_RS07730 becbc2dd9461f606cf4dcb2868b87bda 327 PRINTS PR00069 Aldo-keto reductase signature 144 161 1.2E-6 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS07730 becbc2dd9461f606cf4dcb2868b87bda 327 PRINTS PR00069 Aldo-keto reductase signature 47 71 1.2E-6 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS07730 becbc2dd9461f606cf4dcb2868b87bda 327 PRINTS PR00069 Aldo-keto reductase signature 113 131 1.2E-6 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS07730 becbc2dd9461f606cf4dcb2868b87bda 327 SUPERFAMILY SSF51430 1 322 2.75E-104 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS07730 becbc2dd9461f606cf4dcb2868b87bda 327 Pfam PF00248 Aldo/keto reductase family 15 315 2.5E-76 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS07730 becbc2dd9461f606cf4dcb2868b87bda 327 PANTHER PTHR11732 256 316 3.8E-133 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta TOLA_RS07730 becbc2dd9461f606cf4dcb2868b87bda 327 PANTHER PTHR11732 1 237 3.8E-133 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta TOLA_RS07730 becbc2dd9461f606cf4dcb2868b87bda 327 Gene3D G3DSA:3.20.20.100 1 318 2.4E-106 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS13865 81e051c15d82d5f6a57bb3693c99b2a3 476 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 22-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 TOLA_RS13865 81e051c15d82d5f6a57bb3693c99b2a3 476 PANTHER PTHR11918 1 476 3.3E-220 T 22-04-2016 IPR023970 Methylthiotransferase/radical SAM-type protein TOLA_RS13865 81e051c15d82d5f6a57bb3693c99b2a3 476 Pfam PF01938 TRAM domain 378 439 3.2E-18 T 22-04-2016 IPR002792 TRAM domain TOLA_RS13865 81e051c15d82d5f6a57bb3693c99b2a3 476 PANTHER PTHR11918:SF43 1 476 3.3E-220 T 22-04-2016 TOLA_RS13865 81e051c15d82d5f6a57bb3693c99b2a3 476 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 440 3.0E-197 T 22-04-2016 TOLA_RS13865 81e051c15d82d5f6a57bb3693c99b2a3 476 Pfam PF04055 Radical SAM superfamily 151 325 1.9E-28 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS13865 81e051c15d82d5f6a57bb3693c99b2a3 476 Pfam PF00919 Uncharacterized protein family UPF0004 4 104 1.2E-28 T 22-04-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 TOLA_RS13865 81e051c15d82d5f6a57bb3693c99b2a3 476 Gene3D G3DSA:3.80.30.20 146 380 1.1E-79 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe TOLA_RS13865 81e051c15d82d5f6a57bb3693c99b2a3 476 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 437 7.6E-152 T 22-04-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 TOLA_RS13865 81e051c15d82d5f6a57bb3693c99b2a3 476 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 441 74.078 T 22-04-2016 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 TOLA_RS13865 81e051c15d82d5f6a57bb3693c99b2a3 476 SUPERFAMILY SSF102114 127 375 8.37E-63 T 22-04-2016 TOLA_RS13865 81e051c15d82d5f6a57bb3693c99b2a3 476 SMART SM00729 147 367 3.5E-62 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TOLA_RS14695 c417a689ef1540a080eb4d088d1d0821 378 Gene3D G3DSA:3.10.560.10 236 343 1.6E-32 T 22-04-2016 TOLA_RS14695 c417a689ef1540a080eb4d088d1d0821 378 Gene3D G3DSA:3.10.560.10 160 235 1.2E-28 T 22-04-2016 TOLA_RS14695 c417a689ef1540a080eb4d088d1d0821 378 Pfam PF02563 Polysaccharide biosynthesis/export protein 79 163 4.4E-27 T 22-04-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 TOLA_RS14695 c417a689ef1540a080eb4d088d1d0821 378 Gene3D G3DSA:1.20.5.70 345 378 1.5E-20 T 22-04-2016 TOLA_RS14695 c417a689ef1540a080eb4d088d1d0821 378 PANTHER PTHR33619 1 377 5.0E-82 T 22-04-2016 TOLA_RS14695 c417a689ef1540a080eb4d088d1d0821 378 Gene3D G3DSA:3.30.1950.10 87 159 1.2E-32 T 22-04-2016 TOLA_RS14695 c417a689ef1540a080eb4d088d1d0821 378 Pfam PF10531 SLBB domain 254 301 2.5E-4 T 22-04-2016 IPR019554 Soluble ligand binding domain TOLA_RS14695 c417a689ef1540a080eb4d088d1d0821 378 Pfam PF10531 SLBB domain 170 218 3.7E-9 T 22-04-2016 IPR019554 Soluble ligand binding domain TOLA_RS14695 c417a689ef1540a080eb4d088d1d0821 378 PANTHER PTHR33619:SF3 1 377 5.0E-82 T 22-04-2016 TOLA_RS06430 95b1882a208ab51639a355773f26ad6e 358 SUPERFAMILY SSF51569 4 356 1.83E-129 T 22-04-2016 TOLA_RS06430 95b1882a208ab51639a355773f26ad6e 358 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 4 357 1.1E-184 T 22-04-2016 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|UniPathway: UPA00109 TOLA_RS06430 95b1882a208ab51639a355773f26ad6e 358 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 100 111 - T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TOLA_RS06430 95b1882a208ab51639a355773f26ad6e 358 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 171 182 - T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TOLA_RS06430 95b1882a208ab51639a355773f26ad6e 358 PANTHER PTHR30559 2 358 7.7E-247 T 22-04-2016 TOLA_RS06430 95b1882a208ab51639a355773f26ad6e 358 Gene3D G3DSA:3.20.20.70 11 354 1.1E-123 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS06430 95b1882a208ab51639a355773f26ad6e 358 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 14 356 6.4E-115 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TOLA_RS06430 95b1882a208ab51639a355773f26ad6e 358 PIRSF PIRSF001359 13 358 5.8E-100 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TOLA_RS06430 95b1882a208ab51639a355773f26ad6e 358 Pfam PF01116 Fructose-bisphosphate aldolase class-II 17 354 1.2E-89 T 22-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TOLA_RS06430 95b1882a208ab51639a355773f26ad6e 358 PANTHER PTHR30559:SF0 2 358 7.7E-247 T 22-04-2016 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 SUPERFAMILY SSF51905 349 407 1.47E-47 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 SUPERFAMILY SSF51905 7 196 1.47E-47 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 10 402 1.8E-94 T 22-04-2016 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 PANTHER PTHR10617 1 309 5.2E-57 T 22-04-2016 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 PANTHER PTHR10617 342 409 5.2E-57 T 22-04-2016 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 Gene3D G3DSA:3.50.50.60 7 194 6.4E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 Gene3D G3DSA:3.50.50.60 351 406 6.4E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 Gene3D G3DSA:2.40.30.10 211 291 2.9E-4 T 22-04-2016 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 31 410 4.8E-165 T 22-04-2016 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 PRINTS PR00419 Adrenodoxin reductase family signature 9 31 6.4E-7 T 22-04-2016 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 PRINTS PR00419 Adrenodoxin reductase family signature 32 45 6.4E-7 T 22-04-2016 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 Pfam PF03486 HI0933-like protein 9 403 4.9E-111 T 22-04-2016 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 SUPERFAMILY SSF160996 199 352 2.35E-13 T 22-04-2016 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 PANTHER PTHR10617:SF103 1 309 5.2E-57 T 22-04-2016 TOLA_RS03395 da3e4b808ac20c159f5569a817de4c35 413 PANTHER PTHR10617:SF103 342 409 5.2E-57 T 22-04-2016 TOLA_RS11185 eff4815fe84fe1bdaa65f9bbf3ca1055 302 Gene3D G3DSA:3.40.50.620 2 140 6.4E-24 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS11185 eff4815fe84fe1bdaa65f9bbf3ca1055 302 PANTHER PTHR31964:SF41 1 89 1.2E-48 T 22-04-2016 TOLA_RS11185 eff4815fe84fe1bdaa65f9bbf3ca1055 302 PANTHER PTHR31964:SF41 243 299 1.2E-48 T 22-04-2016 TOLA_RS11185 eff4815fe84fe1bdaa65f9bbf3ca1055 302 SUPERFAMILY SSF52402 4 153 7.62E-27 T 22-04-2016 TOLA_RS11185 eff4815fe84fe1bdaa65f9bbf3ca1055 302 Gene3D G3DSA:3.40.50.620 141 299 2.6E-23 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS11185 eff4815fe84fe1bdaa65f9bbf3ca1055 302 Pfam PF00582 Universal stress protein family 180 299 5.8E-12 T 22-04-2016 IPR006016 UspA GO:0006950 TOLA_RS11185 eff4815fe84fe1bdaa65f9bbf3ca1055 302 Pfam PF00582 Universal stress protein family 4 147 2.4E-18 T 22-04-2016 IPR006016 UspA GO:0006950 TOLA_RS11185 eff4815fe84fe1bdaa65f9bbf3ca1055 302 PANTHER PTHR31964 1 89 1.2E-48 T 22-04-2016 TOLA_RS11185 eff4815fe84fe1bdaa65f9bbf3ca1055 302 PANTHER PTHR31964 243 299 1.2E-48 T 22-04-2016 TOLA_RS11185 eff4815fe84fe1bdaa65f9bbf3ca1055 302 SUPERFAMILY SSF52402 156 299 1.67E-21 T 22-04-2016 TOLA_RS02220 c125d2f44da8a8cea630acd170273e42 192 Gene3D G3DSA:3.40.50.10490 2 190 1.8E-41 T 22-04-2016 TOLA_RS02220 c125d2f44da8a8cea630acd170273e42 192 PANTHER PTHR30390:SF5 1 192 8.4E-85 T 22-04-2016 TOLA_RS02220 c125d2f44da8a8cea630acd170273e42 192 SUPERFAMILY SSF53697 2 190 4.23E-39 T 22-04-2016 TOLA_RS02220 c125d2f44da8a8cea630acd170273e42 192 Pfam PF13580 SIS domain 8 139 2.8E-23 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 TOLA_RS02220 c125d2f44da8a8cea630acd170273e42 192 PANTHER PTHR30390 1 192 8.4E-85 T 22-04-2016 TOLA_RS12520 0ef7c17a4897b70db1bb883c1be88b92 647 SUPERFAMILY SSF53474 358 608 4.49E-23 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS12520 0ef7c17a4897b70db1bb883c1be88b92 647 Gene3D G3DSA:3.40.50.1820 567 622 1.9E-19 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS12520 0ef7c17a4897b70db1bb883c1be88b92 647 Gene3D G3DSA:3.40.50.1820 361 510 1.9E-19 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS12520 0ef7c17a4897b70db1bb883c1be88b92 647 Pfam PF05057 Putative serine esterase (DUF676) 362 480 1.3E-4 T 22-04-2016 IPR007751 Domain of unknown function DUF676, lipase-like TOLA_RS07635 af3543504364f61213e35683a7ad80a2 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 3.3E-20 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07635 af3543504364f61213e35683a7ad80a2 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.3E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07635 af3543504364f61213e35683a7ad80a2 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.3E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07635 af3543504364f61213e35683a7ad80a2 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.3E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07635 af3543504364f61213e35683a7ad80a2 298 Gene3D G3DSA:1.10.10.10 5 87 2.8E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07635 af3543504364f61213e35683a7ad80a2 298 PANTHER PTHR30537 1 297 4.9E-169 T 22-04-2016 TOLA_RS07635 af3543504364f61213e35683a7ad80a2 298 Gene3D G3DSA:3.40.190.10 181 264 1.3E-5 T 22-04-2016 TOLA_RS07635 af3543504364f61213e35683a7ad80a2 298 Pfam PF03466 LysR substrate binding domain 90 294 1.3E-33 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS07635 af3543504364f61213e35683a7ad80a2 298 SUPERFAMILY SSF53850 90 294 2.17E-35 T 22-04-2016 TOLA_RS07635 af3543504364f61213e35683a7ad80a2 298 Gene3D G3DSA:3.40.190.10 94 180 1.1E-17 T 22-04-2016 TOLA_RS07635 af3543504364f61213e35683a7ad80a2 298 SUPERFAMILY SSF46785 5 114 5.98E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07635 af3543504364f61213e35683a7ad80a2 298 PANTHER PTHR30537:SF1 1 297 4.9E-169 T 22-04-2016 TOLA_RS08815 65563ea2ee7b09a3300c005a04f2d463 338 Pfam PF01032 FecCD transport family 25 332 1.1E-84 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 TOLA_RS08815 65563ea2ee7b09a3300c005a04f2d463 338 Gene3D G3DSA:1.10.3470.10 8 334 1.4E-96 T 22-04-2016 IPR029022 ABC transporter, BtuC-like TOLA_RS08815 65563ea2ee7b09a3300c005a04f2d463 338 SUPERFAMILY SSF81345 6 333 2.22E-75 T 22-04-2016 IPR029022 ABC transporter, BtuC-like TOLA_RS08815 65563ea2ee7b09a3300c005a04f2d463 338 PANTHER PTHR30472 9 338 3.5E-100 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 TOLA_RS08815 65563ea2ee7b09a3300c005a04f2d463 338 PANTHER PTHR30472:SF29 9 338 3.5E-100 T 22-04-2016 TOLA_RS07345 e3ead121b710b1c957dac5a98ead779c 327 PANTHER PTHR11082:SF26 14 326 7.8E-156 T 22-04-2016 TOLA_RS07345 e3ead121b710b1c957dac5a98ead779c 327 Hamap MF_02043 tRNA-dihydrouridine(16) synthase [dusC]. 20 322 50.428 T 22-04-2016 IPR032886 tRNA-dihydrouridine(16) synthase GO:0002943|GO:0017150 TOLA_RS07345 e3ead121b710b1c957dac5a98ead779c 327 PANTHER PTHR11082 14 326 7.8E-156 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TOLA_RS07345 e3ead121b710b1c957dac5a98ead779c 327 Gene3D G3DSA:3.20.20.70 12 252 4.0E-55 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS07345 e3ead121b710b1c957dac5a98ead779c 327 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 104 122 - T 22-04-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 TOLA_RS07345 e3ead121b710b1c957dac5a98ead779c 327 SUPERFAMILY SSF51395 14 321 1.28E-60 T 22-04-2016 TOLA_RS07345 e3ead121b710b1c957dac5a98ead779c 327 PIRSF PIRSF006621 4 327 2.2E-70 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TOLA_RS07345 e3ead121b710b1c957dac5a98ead779c 327 Pfam PF01207 Dihydrouridine synthase (Dus) 16 292 9.4E-70 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TOLA_RS07000 20754fa00f15b5dbad44fe6794287355 573 SUPERFAMILY SSF55874 426 564 7.6E-15 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS07000 20754fa00f15b5dbad44fe6794287355 573 SMART SM00387 465 567 0.0052 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS07000 20754fa00f15b5dbad44fe6794287355 573 Pfam PF07694 5TMR of 5TMR-LYT 29 198 1.6E-60 T 22-04-2016 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 TOLA_RS07000 20754fa00f15b5dbad44fe6794287355 573 Gene3D G3DSA:3.30.565.10 422 566 2.0E-15 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS07000 20754fa00f15b5dbad44fe6794287355 573 SUPERFAMILY SSF55781 238 357 5.56E-8 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS07000 20754fa00f15b5dbad44fe6794287355 573 Gene3D G3DSA:3.30.450.40 244 351 6.8E-5 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS07000 20754fa00f15b5dbad44fe6794287355 573 Pfam PF06580 Histidine kinase 373 450 3.2E-25 T 22-04-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 TOLA_RS07000 20754fa00f15b5dbad44fe6794287355 573 Pfam PF13492 GAF domain 245 358 2.6E-7 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS07000 20754fa00f15b5dbad44fe6794287355 573 PANTHER PTHR34220:SF3 4 571 1.2E-261 T 22-04-2016 TOLA_RS07000 20754fa00f15b5dbad44fe6794287355 573 PANTHER PTHR34220 4 571 1.2E-261 T 22-04-2016 TOLA_RS13170 65c67b1324d19ae8bec470a666d49d30 91 SMART SM00411 1 90 8.0E-45 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS13170 65c67b1324d19ae8bec470a666d49d30 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 22-04-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 TOLA_RS13170 65c67b1324d19ae8bec470a666d49d30 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 4.4E-19 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS13170 65c67b1324d19ae8bec470a666d49d30 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 4.4E-19 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS13170 65c67b1324d19ae8bec470a666d49d30 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 4.4E-19 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS13170 65c67b1324d19ae8bec470a666d49d30 91 SUPERFAMILY SSF47729 1 90 4.42E-34 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 TOLA_RS13170 65c67b1324d19ae8bec470a666d49d30 91 Gene3D G3DSA:4.10.520.10 1 90 1.6E-38 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 TOLA_RS13170 65c67b1324d19ae8bec470a666d49d30 91 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.1E-34 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS13170 65c67b1324d19ae8bec470a666d49d30 91 PANTHER PTHR33175 1 90 1.0E-52 T 22-04-2016 TOLA_RS13170 65c67b1324d19ae8bec470a666d49d30 91 PANTHER PTHR33175:SF4 1 90 1.0E-52 T 22-04-2016 TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 19 289 2.0E-116 T 22-04-2016 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 48 180 4.3E-21 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 SMART SM00478 52 203 1.8E-46 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 Pfam PF00633 Helix-hairpin-helix motif 113 140 6.2E-7 T 22-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 ProSitePatterns PS01155 Endonuclease III family signature. 115 144 - T 22-04-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 SUPERFAMILY SSF48150 18 237 1.02E-75 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 Gene3D G3DSA:1.10.1670.10 136 237 1.3E-36 T 22-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 Pfam PF14815 NUDIX domain 248 357 1.0E-20 T 22-04-2016 IPR029119 MutY, C-terminal TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 Gene3D G3DSA:3.90.79.10 244 357 1.2E-19 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 SUPERFAMILY SSF55811 234 357 8.92E-23 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 SMART SM00525 204 224 0.0039 T 22-04-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 PANTHER PTHR10359 19 346 3.6E-97 T 22-04-2016 TOLA_RS04930 39f8b0ab9ea208c1311ead2555e553d8 363 Gene3D G3DSA:1.10.340.30 35 135 3.0E-45 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 TOLA_RS04730 e4c916a3ecd99e7bf1decc0fbc7cd6f2 280 Gene3D G3DSA:1.25.40.10 197 280 2.7E-25 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS04730 e4c916a3ecd99e7bf1decc0fbc7cd6f2 280 Gene3D G3DSA:1.25.40.10 109 195 4.8E-23 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS04730 e4c916a3ecd99e7bf1decc0fbc7cd6f2 280 PANTHER PTHR10438:SF288 2 111 2.5E-15 T 22-04-2016 TOLA_RS04730 e4c916a3ecd99e7bf1decc0fbc7cd6f2 280 PANTHER PTHR10438:SF288 214 235 2.5E-15 T 22-04-2016 TOLA_RS04730 e4c916a3ecd99e7bf1decc0fbc7cd6f2 280 Pfam PF00085 Thioredoxin 2 104 2.0E-10 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 TOLA_RS04730 e4c916a3ecd99e7bf1decc0fbc7cd6f2 280 PANTHER PTHR10438 2 111 2.5E-15 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TOLA_RS04730 e4c916a3ecd99e7bf1decc0fbc7cd6f2 280 PANTHER PTHR10438 214 235 2.5E-15 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TOLA_RS04730 e4c916a3ecd99e7bf1decc0fbc7cd6f2 280 SUPERFAMILY SSF52833 2 110 1.26E-18 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS04730 e4c916a3ecd99e7bf1decc0fbc7cd6f2 280 Gene3D G3DSA:3.40.30.10 2 108 2.8E-16 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS04730 e4c916a3ecd99e7bf1decc0fbc7cd6f2 280 Pfam PF14559 Tetratricopeptide repeat 123 188 3.8E-13 T 22-04-2016 TOLA_RS04730 e4c916a3ecd99e7bf1decc0fbc7cd6f2 280 SUPERFAMILY SSF48452 110 251 3.57E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS04730 e4c916a3ecd99e7bf1decc0fbc7cd6f2 280 Pfam PF14561 Tetratricopeptide repeat 194 280 5.8E-24 T 22-04-2016 TOLA_RS11330 866e703169def3f8abcff62cad1f619f 254 PANTHER PTHR21485:SF4 1 247 5.4E-123 T 22-04-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 TOLA_RS11330 866e703169def3f8abcff62cad1f619f 254 PANTHER PTHR21485 1 247 5.4E-123 T 22-04-2016 TOLA_RS11330 866e703169def3f8abcff62cad1f619f 254 Gene3D G3DSA:3.90.550.10 1 248 1.7E-87 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS11330 866e703169def3f8abcff62cad1f619f 254 SUPERFAMILY SSF53448 3 247 1.04E-65 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS11330 866e703169def3f8abcff62cad1f619f 254 Hamap MF_00057 3-deoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 248 45.424 T 22-04-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 TOLA_RS11330 866e703169def3f8abcff62cad1f619f 254 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 1 241 1.5E-113 T 22-04-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 TOLA_RS11330 866e703169def3f8abcff62cad1f619f 254 Pfam PF02348 Cytidylyltransferase 4 221 5.6E-64 T 22-04-2016 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 TOLA_RS15870 15dbf99235e8c8ca9b599565d3f188a6 307 ProSitePatterns PS00770 Aminotransferases class-IV signature. 192 221 - T 22-04-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 TOLA_RS15870 15dbf99235e8c8ca9b599565d3f188a6 307 PANTHER PTHR11825 7 304 2.6E-120 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 TOLA_RS15870 15dbf99235e8c8ca9b599565d3f188a6 307 SUPERFAMILY SSF56752 3 302 6.41E-101 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 TOLA_RS15870 15dbf99235e8c8ca9b599565d3f188a6 307 PANTHER PTHR11825:SF7 7 304 2.6E-120 T 22-04-2016 TOLA_RS15870 15dbf99235e8c8ca9b599565d3f188a6 307 Pfam PF01063 Amino-transferase class IV 35 266 2.3E-52 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 TOLA_RS15870 15dbf99235e8c8ca9b599565d3f188a6 307 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 9 305 4.0E-132 T 22-04-2016 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|UniPathway: UPA00047|UniPathway: UPA00048|UniPathway: UPA00049 TOLA_RS15870 15dbf99235e8c8ca9b599565d3f188a6 307 Gene3D G3DSA:3.30.470.10 6 128 3.2E-40 T 22-04-2016 TOLA_RS15870 15dbf99235e8c8ca9b599565d3f188a6 307 Gene3D G3DSA:3.20.10.10 134 293 2.6E-56 T 22-04-2016 TOLA_RS10770 f7775df8c3fe3e695f7cf4a065629638 332 PANTHER PTHR30465:SF43 1 331 8.4E-95 T 22-04-2016 TOLA_RS10770 f7775df8c3fe3e695f7cf4a065629638 332 Gene3D G3DSA:1.10.3720.10 98 323 2.5E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10770 f7775df8c3fe3e695f7cf4a065629638 332 PANTHER PTHR30465 1 331 8.4E-95 T 22-04-2016 TOLA_RS10770 f7775df8c3fe3e695f7cf4a065629638 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 330 2.6E-29 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10770 f7775df8c3fe3e695f7cf4a065629638 332 SUPERFAMILY SSF161098 99 313 4.32E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 384 496 1.6E-11 T 22-04-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 316 322 1.7E-29 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 30 1.7E-29 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 7 19 1.7E-29 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 350 362 1.7E-29 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 36 48 1.7E-29 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 81 93 1.7E-29 T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 PANTHER PTHR11985:SF1 7 512 9.3E-182 T 22-04-2016 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 SUPERFAMILY SSF51905 1 263 8.06E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 SUPERFAMILY SSF51905 315 375 8.06E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 Pfam PF01266 FAD dependent oxidoreductase 8 326 8.7E-47 T 22-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 12 29 - T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 Gene3D G3DSA:3.50.50.60 6 304 3.4E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 355 365 - T 22-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 TOLA_RS00365 f13b016ef9e0668262eab44c98ee0a0d 512 PANTHER PTHR11985 7 512 9.3E-182 T 22-04-2016 TOLA_RS08545 460bc72e1c80fbe50669eb146fb2acc6 319 PANTHER PTHR34308:SF1 4 319 7.7E-108 T 22-04-2016 TOLA_RS08545 460bc72e1c80fbe50669eb146fb2acc6 319 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 5 302 2.6E-73 T 22-04-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 TOLA_RS08545 460bc72e1c80fbe50669eb146fb2acc6 319 PANTHER PTHR34308 4 319 7.7E-108 T 22-04-2016 TOLA_RS08545 460bc72e1c80fbe50669eb146fb2acc6 319 Pfam PF03186 CobD/Cbib protein 8 297 1.6E-106 T 22-04-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 TOLA_RS08545 460bc72e1c80fbe50669eb146fb2acc6 319 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 318 100.43 T 22-04-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 TOLA_RS00190 22c2f118659d82b1f3bff85df8da3243 317 Gene3D G3DSA:3.90.25.10 175 298 7.4E-37 T 22-04-2016 TOLA_RS00190 22c2f118659d82b1f3bff85df8da3243 317 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 316 3.3E-136 T 22-04-2016 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20|UniPathway: UPA00356 TOLA_RS00190 22c2f118659d82b1f3bff85df8da3243 317 PANTHER PTHR10366:SF469 1 317 8.0E-117 T 22-04-2016 TOLA_RS00190 22c2f118659d82b1f3bff85df8da3243 317 Gene3D G3DSA:3.40.50.720 2 174 3.9E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00190 22c2f118659d82b1f3bff85df8da3243 317 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 317 58.897 T 22-04-2016 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20|UniPathway: UPA00356 TOLA_RS00190 22c2f118659d82b1f3bff85df8da3243 317 PANTHER PTHR10366 1 317 8.0E-117 T 22-04-2016 TOLA_RS00190 22c2f118659d82b1f3bff85df8da3243 317 SUPERFAMILY SSF51735 1 315 1.51E-65 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00190 22c2f118659d82b1f3bff85df8da3243 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 245 1.0E-46 T 22-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 TOLA_RS05470 71c61aaab466fcf071a03c5d46735d16 169 SUPERFAMILY SSF50814 5 169 9.98E-52 T 22-04-2016 IPR011038 Calycin-like TOLA_RS05470 71c61aaab466fcf071a03c5d46735d16 169 Gene3D G3DSA:2.40.128.20 6 169 8.4E-58 T 22-04-2016 IPR012674 Calycin TOLA_RS05470 71c61aaab466fcf071a03c5d46735d16 169 PANTHER PTHR10612 11 169 5.8E-52 T 22-04-2016 TOLA_RS05470 71c61aaab466fcf071a03c5d46735d16 169 PRINTS PR01171 Bacterial lipocalin signature 45 61 1.2E-32 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 TOLA_RS05470 71c61aaab466fcf071a03c5d46735d16 169 PRINTS PR01171 Bacterial lipocalin signature 158 168 1.2E-32 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 TOLA_RS05470 71c61aaab466fcf071a03c5d46735d16 169 PRINTS PR01171 Bacterial lipocalin signature 28 42 1.2E-32 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 TOLA_RS05470 71c61aaab466fcf071a03c5d46735d16 169 PRINTS PR01171 Bacterial lipocalin signature 131 142 1.2E-32 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 TOLA_RS05470 71c61aaab466fcf071a03c5d46735d16 169 PRINTS PR01171 Bacterial lipocalin signature 98 112 1.2E-32 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 TOLA_RS05470 71c61aaab466fcf071a03c5d46735d16 169 PRINTS PR01171 Bacterial lipocalin signature 64 73 1.2E-32 T 22-04-2016 IPR002446 Lipocalin, bacterial GO:0005215 TOLA_RS05470 71c61aaab466fcf071a03c5d46735d16 169 ProSitePatterns PS00213 Lipocalin signature. 27 40 - T 22-04-2016 IPR022272 Lipocalin family conserved site TOLA_RS05470 71c61aaab466fcf071a03c5d46735d16 169 Pfam PF08212 Lipocalin-like domain 28 169 3.9E-46 T 22-04-2016 IPR000566 Lipocalin/cytosolic fatty-acid binding domain TOLA_RS05470 71c61aaab466fcf071a03c5d46735d16 169 PIRSF PIRSF036893 1 169 9.5E-47 T 22-04-2016 IPR022271 Lipocalin, ApoD type TOLA_RS08600 141731e9ffbe5fea8af697b060b8708e 91 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 4 47 1.0E-16 T 22-04-2016 TOLA_RS08600 141731e9ffbe5fea8af697b060b8708e 91 PANTHER PTHR33941 1 90 1.0E-45 T 22-04-2016 TOLA_RS08600 141731e9ffbe5fea8af697b060b8708e 91 Pfam PF00936 BMC domain 4 79 8.9E-30 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08600 141731e9ffbe5fea8af697b060b8708e 91 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 21 40 - T 22-04-2016 IPR020808 Bacterial microcompartments protein, conserved site TOLA_RS08600 141731e9ffbe5fea8af697b060b8708e 91 SUPERFAMILY SSF143414 3 89 6.41E-34 T 22-04-2016 TOLA_RS08600 141731e9ffbe5fea8af697b060b8708e 91 SMART SM00877 3 79 1.9E-39 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS11455 ed1ce8a2ad886675105dee2a7812b999 158 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 1.9E-31 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TOLA_RS11455 ed1ce8a2ad886675105dee2a7812b999 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 2.7E-27 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TOLA_RS11455 ed1ce8a2ad886675105dee2a7812b999 158 PANTHER PTHR30437 1 157 4.4E-69 T 22-04-2016 TOLA_RS11455 ed1ce8a2ad886675105dee2a7812b999 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 156 1.4E-58 T 22-04-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 TOLA_RS11455 ed1ce8a2ad886675105dee2a7812b999 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 22-04-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TOLA_RS11455 ed1ce8a2ad886675105dee2a7812b999 158 SUPERFAMILY SSF46557 3 78 8.5E-29 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TOLA_RS11455 ed1ce8a2ad886675105dee2a7812b999 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 22-04-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TOLA_RS11455 ed1ce8a2ad886675105dee2a7812b999 158 SUPERFAMILY SSF54534 82 157 7.32E-23 T 22-04-2016 TOLA_RS11455 ed1ce8a2ad886675105dee2a7812b999 158 PIRSF PIRSF006092 1 158 2.8E-53 T 22-04-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TOLA_RS11455 ed1ce8a2ad886675105dee2a7812b999 158 Gene3D G3DSA:3.10.50.30 81 157 5.0E-29 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TOLA_RS11455 ed1ce8a2ad886675105dee2a7812b999 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 32.96 T 22-04-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 TOLA_RS11455 ed1ce8a2ad886675105dee2a7812b999 158 Gene3D G3DSA:1.10.287.180 1 75 5.9E-35 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TOLA_RS08495 cd808db3beebebcbdebfc423cbcc3a41 241 PANTHER PTHR21091:SF121 1 151 1.3E-49 T 22-04-2016 TOLA_RS08495 cd808db3beebebcbdebfc423cbcc3a41 241 SUPERFAMILY SSF53790 1 232 5.63E-44 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS08495 cd808db3beebebcbdebfc423cbcc3a41 241 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 3 231 7.1E-76 T 22-04-2016 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 TOLA_RS08495 cd808db3beebebcbdebfc423cbcc3a41 241 Gene3D G3DSA:3.40.1010.10 1 127 6.8E-29 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 TOLA_RS08495 cd808db3beebebcbdebfc423cbcc3a41 241 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 22-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS08495 cd808db3beebebcbdebfc423cbcc3a41 241 PIRSF PIRSF036427 1 237 2.0E-70 T 22-04-2016 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 TOLA_RS08495 cd808db3beebebcbdebfc423cbcc3a41 241 PANTHER PTHR21091 1 151 1.3E-49 T 22-04-2016 TOLA_RS08495 cd808db3beebebcbdebfc423cbcc3a41 241 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 94 126 - T 22-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS08495 cd808db3beebebcbdebfc423cbcc3a41 241 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 210 3.9E-42 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS14950 414a4663dd2d6a8fae8f2afbcf313570 293 SUPERFAMILY SSF81345 14 272 3.4E-20 T 22-04-2016 IPR029022 ABC transporter, BtuC-like TOLA_RS14950 414a4663dd2d6a8fae8f2afbcf313570 293 PANTHER PTHR30477 11 292 2.5E-66 T 22-04-2016 TOLA_RS14950 414a4663dd2d6a8fae8f2afbcf313570 293 Pfam PF00950 ABC 3 transport family 17 274 1.8E-48 T 22-04-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 TOLA_RS14950 414a4663dd2d6a8fae8f2afbcf313570 293 PANTHER PTHR30477:SF3 11 292 2.5E-66 T 22-04-2016 TOLA_RS13670 78d33257f4eb2160636c016ffe103ad3 246 Pfam PF02308 MgtC family 29 156 3.3E-32 T 22-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TOLA_RS13670 78d33257f4eb2160636c016ffe103ad3 246 PRINTS PR01837 MgtC/SapB protein signature 48 66 7.3E-37 T 22-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TOLA_RS13670 78d33257f4eb2160636c016ffe103ad3 246 PRINTS PR01837 MgtC/SapB protein signature 29 48 7.3E-37 T 22-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TOLA_RS13670 78d33257f4eb2160636c016ffe103ad3 246 PRINTS PR01837 MgtC/SapB protein signature 110 134 7.3E-37 T 22-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TOLA_RS13670 78d33257f4eb2160636c016ffe103ad3 246 PRINTS PR01837 MgtC/SapB protein signature 83 105 7.3E-37 T 22-04-2016 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 TOLA_RS13670 78d33257f4eb2160636c016ffe103ad3 246 PANTHER PTHR33778 22 158 1.1E-38 T 22-04-2016 TOLA_RS13670 78d33257f4eb2160636c016ffe103ad3 246 SUPERFAMILY SSF103473 5 162 2.49E-6 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 PANTHER PTHR12815:SF11 5 678 1.4E-253 T 22-04-2016 TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 PANTHER PTHR12815:SF11 694 807 1.4E-253 T 22-04-2016 TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 PANTHER PTHR12815 5 678 1.4E-253 T 22-04-2016 TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 PANTHER PTHR12815 694 807 1.4E-253 T 22-04-2016 TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 PIRSF PIRSF006076 1 807 7.7E-249 T 22-04-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 Gene3D G3DSA:2.40.160.50 393 807 7.2E-21 T 22-04-2016 TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 Pfam PF01103 Surface antigen 451 807 1.7E-89 T 22-04-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 1 807 25.477 T 22-04-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 Pfam PF07244 Surface antigen variable number repeat 269 347 2.4E-10 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 Pfam PF07244 Surface antigen variable number repeat 350 424 1.9E-15 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 Pfam PF07244 Surface antigen variable number repeat 95 175 5.5E-11 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 Pfam PF07244 Surface antigen variable number repeat 179 266 1.2E-18 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 TOLA_RS10695 56716734f9fb9b470d9877d679fb5f60 807 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 27 807 1.9E-274 T 22-04-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 TOLA_RS00350 a73d0179279ac9659588118681015ff9 489 Gene3D G3DSA:3.40.50.300 211 370 6.3E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00350 a73d0179279ac9659588118681015ff9 489 Pfam PF00271 Helicase conserved C-terminal domain 230 338 1.6E-25 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS00350 a73d0179279ac9659588118681015ff9 489 PANTHER PTHR24031:SF0 1 475 7.2E-190 T 22-04-2016 TOLA_RS00350 a73d0179279ac9659588118681015ff9 489 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TOLA_RS00350 a73d0179279ac9659588118681015ff9 489 Gene3D G3DSA:3.40.50.300 1 210 1.7E-82 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00350 a73d0179279ac9659588118681015ff9 489 PANTHER PTHR24031 1 475 7.2E-190 T 22-04-2016 TOLA_RS00350 a73d0179279ac9659588118681015ff9 489 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 1 478 49.662 T 22-04-2016 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 TOLA_RS00350 a73d0179279ac9659588118681015ff9 489 SMART SM00487 20 221 2.2E-64 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS00350 a73d0179279ac9659588118681015ff9 489 Pfam PF00270 DEAD/DEAH box helicase 26 193 2.6E-49 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS00350 a73d0179279ac9659588118681015ff9 489 SUPERFAMILY SSF52540 73 356 5.61E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00350 a73d0179279ac9659588118681015ff9 489 SMART SM00490 257 338 8.3E-27 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS01385 dc7f319bd6a87d2a0aebe7e2fb027673 447 Pfam PF01523 Putative modulator of DNA gyrase 33 324 8.4E-49 T 22-04-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS01385 dc7f319bd6a87d2a0aebe7e2fb027673 447 PANTHER PTHR30624:SF1 6 447 9.6E-172 T 22-04-2016 TOLA_RS01385 dc7f319bd6a87d2a0aebe7e2fb027673 447 SUPERFAMILY SSF111283 14 447 4.45E-124 T 22-04-2016 TOLA_RS01385 dc7f319bd6a87d2a0aebe7e2fb027673 447 PANTHER PTHR30624 6 447 9.6E-172 T 22-04-2016 TOLA_RS07605 d171eb4bf0cb9ef9568a5d859e6996c5 385 PANTHER PTHR11496:SF65 1 385 1.2E-214 T 22-04-2016 TOLA_RS07605 d171eb4bf0cb9ef9568a5d859e6996c5 385 Gene3D G3DSA:3.40.50.1970 10 181 2.3E-57 T 22-04-2016 TOLA_RS07605 d171eb4bf0cb9ef9568a5d859e6996c5 385 PANTHER PTHR11496 1 385 1.2E-214 T 22-04-2016 TOLA_RS07605 d171eb4bf0cb9ef9568a5d859e6996c5 385 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 262 282 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS07605 d171eb4bf0cb9ef9568a5d859e6996c5 385 SUPERFAMILY SSF56796 1 382 5.23E-108 T 22-04-2016 TOLA_RS07605 d171eb4bf0cb9ef9568a5d859e6996c5 385 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 358 2.4E-91 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 TOLA_RS07605 d171eb4bf0cb9ef9568a5d859e6996c5 385 Gene3D G3DSA:1.20.1090.10 182 384 1.1E-50 T 22-04-2016 TOLA_RS00155 d1cac47c968355753031bc27cd9d40df 114 PANTHER PTHR33215 8 113 5.9E-22 T 22-04-2016 TOLA_RS00155 d1cac47c968355753031bc27cd9d40df 114 Pfam PF01527 Transposase 12 88 8.8E-16 T 22-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 TOLA_RS00155 d1cac47c968355753031bc27cd9d40df 114 SUPERFAMILY SSF46689 12 107 1.97E-18 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS00155 d1cac47c968355753031bc27cd9d40df 114 Gene3D G3DSA:1.10.10.60 14 101 1.8E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS11750 e639a912803db3838b7bffe4f662e402 448 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 52 158 5.3E-15 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS11750 e639a912803db3838b7bffe4f662e402 448 Gene3D G3DSA:1.10.3710.10 345 441 1.8E-32 T 22-04-2016 TOLA_RS11750 e639a912803db3838b7bffe4f662e402 448 Gene3D G3DSA:1.20.272.10 246 344 6.1E-42 T 22-04-2016 TOLA_RS11750 e639a912803db3838b7bffe4f662e402 448 PANTHER PTHR13779 11 447 2.4E-190 T 22-04-2016 TOLA_RS11750 e639a912803db3838b7bffe4f662e402 448 SUPERFAMILY SSF52540 12 228 5.11E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11750 e639a912803db3838b7bffe4f662e402 448 Pfam PF12002 MgsA AAA+ ATPase C terminal 265 431 1.2E-64 T 22-04-2016 IPR021886 MgsA AAA+ ATPase C-terminal TOLA_RS11750 e639a912803db3838b7bffe4f662e402 448 Gene3D G3DSA:3.40.50.300 12 152 3.2E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11750 e639a912803db3838b7bffe4f662e402 448 SMART SM00382 48 164 3.4E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS11750 e639a912803db3838b7bffe4f662e402 448 PANTHER PTHR13779:SF7 11 447 2.4E-190 T 22-04-2016 TOLA_RS11750 e639a912803db3838b7bffe4f662e402 448 Gene3D G3DSA:1.10.8.60 153 224 6.1E-10 T 22-04-2016 TOLA_RS11750 e639a912803db3838b7bffe4f662e402 448 Pfam PF16193 AAA C-terminal domain 186 264 8.1E-22 T 22-04-2016 IPR032423 AAA ATPase, C-terminal domain TOLA_RS11750 e639a912803db3838b7bffe4f662e402 448 SUPERFAMILY SSF48019 249 431 3.74E-71 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 TOLA_RS15055 16cc670a6db64073f2228ee14a0f2722 187 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 8 183 5.8E-37 T 22-04-2016 IPR010664 Lipopolysaccharide assembly, LptC-related TOLA_RS15055 16cc670a6db64073f2228ee14a0f2722 187 PIRSF PIRSF028513 1 187 2.3E-37 T 22-04-2016 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 TOLA_RS15055 16cc670a6db64073f2228ee14a0f2722 187 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 6 183 2.4E-42 T 22-04-2016 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 TOLA_RS15055 16cc670a6db64073f2228ee14a0f2722 187 Hamap MF_01915 Lipopolysaccharide export system protein LptC [lptC]. 2 186 20.845 T 22-04-2016 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 TOLA_RS15055 16cc670a6db64073f2228ee14a0f2722 187 PANTHER PTHR37481 1 178 6.3E-26 T 22-04-2016 TOLA_RS15055 16cc670a6db64073f2228ee14a0f2722 187 PANTHER PTHR37481:SF1 1 178 6.3E-26 T 22-04-2016 TOLA_RS05360 c41fdc18d3da014e60d22a983a014a6d 419 Gene3D G3DSA:3.20.20.150 4 419 7.3E-221 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS05360 c41fdc18d3da014e60d22a983a014a6d 419 Pfam PF06134 L-rhamnose isomerase (RhaA) 4 418 5.6E-222 T 22-04-2016 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14|UniPathway: UPA00541 TOLA_RS05360 c41fdc18d3da014e60d22a983a014a6d 419 TIGRFAM TIGR01748 rhaA: L-rhamnose isomerase 5 418 2.3E-227 T 22-04-2016 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14|UniPathway: UPA00541 TOLA_RS05360 c41fdc18d3da014e60d22a983a014a6d 419 Hamap MF_00541 L-rhamnose isomerase [rhaA]. 1 419 260.27 T 22-04-2016 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14|UniPathway: UPA00541 TOLA_RS05360 c41fdc18d3da014e60d22a983a014a6d 419 PANTHER PTHR30268 1 419 7.2E-213 T 22-04-2016 TOLA_RS05360 c41fdc18d3da014e60d22a983a014a6d 419 SUPERFAMILY SSF51658 4 417 6.5E-84 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS05360 c41fdc18d3da014e60d22a983a014a6d 419 ProDom PD042532 ISOMERASE L-RHAMNOSE METAL-BINDING METABOLISM RHAMNOSE MANGANESE ENZYME KINASE 3D-STRUCTURE RHAA/RHAB 20 418 0.0 T 22-04-2016 TOLA_RS14865 0e9d865d38d2d11619048f21f473f595 265 PANTHER PTHR24220 5 216 5.7E-82 T 22-04-2016 TOLA_RS14865 0e9d865d38d2d11619048f21f473f595 265 SMART SM00382 28 218 4.4E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS14865 0e9d865d38d2d11619048f21f473f595 265 SUPERFAMILY SSF52540 3 219 2.53E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14865 0e9d865d38d2d11619048f21f473f595 265 Pfam PF00005 ABC transporter 19 168 1.8E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS14865 0e9d865d38d2d11619048f21f473f595 265 Gene3D G3DSA:3.40.50.300 2 216 2.4E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14865 0e9d865d38d2d11619048f21f473f595 265 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS15035 f8f63be95d59dcc37e7ad89e189f2d57 259 PANTHER PTHR30188 1 259 1.4E-118 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 TOLA_RS15035 f8f63be95d59dcc37e7ad89e189f2d57 259 Pfam PF02405 Permease MlaE 45 255 4.7E-72 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 TOLA_RS15035 f8f63be95d59dcc37e7ad89e189f2d57 259 PANTHER PTHR30188:SF4 1 259 1.4E-118 T 22-04-2016 TOLA_RS15035 f8f63be95d59dcc37e7ad89e189f2d57 259 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 5 259 4.1E-98 T 22-04-2016 IPR003453 ABC transport permease subunit MlaE, Proteobacteria TOLA_RS15340 2bea45946196acb4e003afd801583e0d 457 Gene3D G3DSA:2.40.50.100 257 289 1.3E-10 T 22-04-2016 TOLA_RS15340 2bea45946196acb4e003afd801583e0d 457 Gene3D G3DSA:2.40.50.100 163 197 1.3E-10 T 22-04-2016 TOLA_RS15340 2bea45946196acb4e003afd801583e0d 457 PANTHER PTHR30097 43 457 2.5E-98 T 22-04-2016 TOLA_RS15340 2bea45946196acb4e003afd801583e0d 457 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 145 363 2.0E-81 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TOLA_RS15340 2bea45946196acb4e003afd801583e0d 457 SUPERFAMILY SSF111369 162 368 4.84E-17 T 22-04-2016 TOLA_RS15340 2bea45946196acb4e003afd801583e0d 457 PANTHER PTHR30097:SF3 43 457 2.5E-98 T 22-04-2016 TOLA_RS15340 2bea45946196acb4e003afd801583e0d 457 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 260 441 2.9E-33 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 TOLA_RS12765 a656f0605c419957087986821de0db1a 98 SUPERFAMILY SSF46785 4 93 1.41E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS12765 a656f0605c419957087986821de0db1a 98 PANTHER PTHR33154 1 92 1.8E-15 T 22-04-2016 TOLA_RS12765 a656f0605c419957087986821de0db1a 98 Gene3D G3DSA:1.10.10.10 3 96 1.5E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS12765 a656f0605c419957087986821de0db1a 98 SMART SM00418 8 89 2.6E-9 T 22-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TOLA_RS12765 a656f0605c419957087986821de0db1a 98 PANTHER PTHR33154:SF5 1 92 1.8E-15 T 22-04-2016 TOLA_RS12765 a656f0605c419957087986821de0db1a 98 Pfam PF12840 Helix-turn-helix domain 9 69 2.5E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS04435 0334fc458638bffadfc0de592cb72790 332 SMART SM00382 32 242 0.0023 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS04435 0334fc458638bffadfc0de592cb72790 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 323 3.4E-22 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TOLA_RS04435 0334fc458638bffadfc0de592cb72790 332 Gene3D G3DSA:3.40.50.300 2 260 1.4E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04435 0334fc458638bffadfc0de592cb72790 332 PANTHER PTHR24220:SF514 5 329 6.2E-172 T 22-04-2016 TOLA_RS04435 0334fc458638bffadfc0de592cb72790 332 PANTHER PTHR24220 5 329 6.2E-172 T 22-04-2016 TOLA_RS04435 0334fc458638bffadfc0de592cb72790 332 SUPERFAMILY SSF52540 3 268 4.6E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04435 0334fc458638bffadfc0de592cb72790 332 Pfam PF00005 ABC transporter 24 186 7.7E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS04435 0334fc458638bffadfc0de592cb72790 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 305 2.0E-16 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TOLA_RS08800 cf07c37df44c97a573a49e49f149fe2d 95 Gene3D G3DSA:2.40.240.10 3 94 4.9E-33 T 22-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 TOLA_RS08800 cf07c37df44c97a573a49e49f149fe2d 95 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 5 94 5.0E-31 T 22-04-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TOLA_RS08800 cf07c37df44c97a573a49e49f149fe2d 95 SUPERFAMILY SSF50715 3 94 2.62E-30 T 22-04-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: REACT_71 TOLA_RS08800 cf07c37df44c97a573a49e49f149fe2d 95 PANTHER PTHR33284 1 95 3.0E-34 T 22-04-2016 TOLA_RS08800 cf07c37df44c97a573a49e49f149fe2d 95 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 7 93 3.8E-21 T 22-04-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TOLA_RS08800 cf07c37df44c97a573a49e49f149fe2d 95 Pfam PF01386 Ribosomal L25p family 7 92 6.3E-24 T 22-04-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TOLA_RS08800 cf07c37df44c97a573a49e49f149fe2d 95 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 3 95 27.063 T 22-04-2016 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 34 191 35.558 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 213 336 35.003 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 PANTHER PTHR10173:SF31 315 352 4.2E-80 T 22-04-2016 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 PANTHER PTHR10173:SF31 29 179 4.2E-80 T 22-04-2016 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 35 184 7.7E-56 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 SUPERFAMILY SSF51316 216 351 8.89E-58 T 22-04-2016 IPR011057 Mss4-like TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 PANTHER PTHR10173 315 352 4.2E-80 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 PANTHER PTHR10173 29 179 4.2E-80 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 Gene3D G3DSA:3.30.1060.10 22 184 4.6E-67 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 Gene3D G3DSA:2.170.150.20 214 351 5.2E-57 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 216 344 2.2E-58 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 Pfam PF01641 SelR domain 217 335 2.2E-45 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 Pfam PF01625 Peptide methionine sulfoxide reductase 36 185 8.8E-57 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 TOLA_RS05145 868acb217d6e496a433fd1d4686e99c1 352 SUPERFAMILY SSF55068 27 196 6.02E-71 T 22-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 TOLA_RS04195 c8fb82ecefd8e4e4e5670c250da0c62a 285 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 7 281 2.1E-93 T 22-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS04195 c8fb82ecefd8e4e4e5670c250da0c62a 285 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 7 273 32.573 T 22-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS04195 c8fb82ecefd8e4e4e5670c250da0c62a 285 Pfam PF08544 GHMP kinases C terminal 197 256 8.9E-8 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain TOLA_RS04195 c8fb82ecefd8e4e4e5670c250da0c62a 285 Gene3D G3DSA:3.30.70.890 165 280 8.8E-43 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain TOLA_RS04195 c8fb82ecefd8e4e4e5670c250da0c62a 285 Gene3D G3DSA:3.30.230.10 8 161 1.7E-51 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS04195 c8fb82ecefd8e4e4e5670c250da0c62a 285 Pfam PF00288 GHMP kinases N terminal domain 90 146 1.9E-10 T 22-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 TOLA_RS04195 c8fb82ecefd8e4e4e5670c250da0c62a 285 PANTHER PTHR20861 5 277 4.0E-92 T 22-04-2016 TOLA_RS04195 c8fb82ecefd8e4e4e5670c250da0c62a 285 PANTHER PTHR20861:SF2 5 277 4.0E-92 T 22-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS04195 c8fb82ecefd8e4e4e5670c250da0c62a 285 SUPERFAMILY SSF55060 164 280 3.93E-37 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain TOLA_RS04195 c8fb82ecefd8e4e4e5670c250da0c62a 285 SUPERFAMILY SSF54211 7 160 4.63E-43 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS04195 c8fb82ecefd8e4e4e5670c250da0c62a 285 PIRSF PIRSF010376 5 281 2.7E-83 T 22-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS10600 d7f7272624385d714367ef7bffdbb1aa 312 SUPERFAMILY SSF81464 23 112 3.92E-26 T 22-04-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 TOLA_RS10600 d7f7272624385d714367ef7bffdbb1aa 312 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 145 216 7.7E-7 T 22-04-2016 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 TOLA_RS10600 d7f7272624385d714367ef7bffdbb1aa 312 PIRSF PIRSF000292 1 306 1.1E-131 T 22-04-2016 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 TOLA_RS10600 d7f7272624385d714367ef7bffdbb1aa 312 PANTHER PTHR22888:SF13 16 262 5.0E-145 T 22-04-2016 TOLA_RS10600 d7f7272624385d714367ef7bffdbb1aa 312 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 14 234 1.5E-114 T 22-04-2016 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 TOLA_RS10600 d7f7272624385d714367ef7bffdbb1aa 312 Gene3D G3DSA:2.60.40.420 117 274 2.7E-41 T 22-04-2016 IPR008972 Cupredoxin TOLA_RS10600 d7f7272624385d714367ef7bffdbb1aa 312 PANTHER PTHR22888 16 262 5.0E-145 T 22-04-2016 TOLA_RS10600 d7f7272624385d714367ef7bffdbb1aa 312 Pfam PF06481 COX Aromatic Rich Motif 234 278 1.5E-16 T 22-04-2016 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 TOLA_RS10600 d7f7272624385d714367ef7bffdbb1aa 312 SUPERFAMILY SSF49503 117 276 4.34E-50 T 22-04-2016 IPR008972 Cupredoxin TOLA_RS10600 d7f7272624385d714367ef7bffdbb1aa 312 Gene3D G3DSA:1.10.287.90 23 108 1.5E-38 T 22-04-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 TOLA_RS06795 3d076120f601e2afefc988613715fea2 283 Gene3D G3DSA:1.20.1290.10 182 281 6.1E-24 T 22-04-2016 IPR029032 AhpD-like TOLA_RS06795 3d076120f601e2afefc988613715fea2 283 Pfam PF07883 Cupin domain 78 138 5.1E-11 T 22-04-2016 IPR013096 Cupin 2, conserved barrel TOLA_RS06795 3d076120f601e2afefc988613715fea2 283 PANTHER PTHR33570 178 278 2.4E-51 T 22-04-2016 TOLA_RS06795 3d076120f601e2afefc988613715fea2 283 SUPERFAMILY SSF51182 51 166 4.74E-31 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS06795 3d076120f601e2afefc988613715fea2 283 PANTHER PTHR33570:SF1 178 278 2.4E-51 T 22-04-2016 TOLA_RS06795 3d076120f601e2afefc988613715fea2 283 SUPERFAMILY SSF69118 180 279 6.15E-29 T 22-04-2016 IPR029032 AhpD-like TOLA_RS06795 3d076120f601e2afefc988613715fea2 283 Pfam PF02627 Carboxymuconolactone decarboxylase family 191 275 6.7E-20 T 22-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS06795 3d076120f601e2afefc988613715fea2 283 Gene3D G3DSA:2.60.120.10 52 167 5.1E-31 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS12940 4fbd4064b8c2989868afbf2922147492 198 SUPERFAMILY SSF52540 22 194 1.28E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12940 4fbd4064b8c2989868afbf2922147492 198 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 7 190 3.1E-81 T 22-04-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: REACT_13433|UniPathway: UPA00140 TOLA_RS12940 4fbd4064b8c2989868afbf2922147492 198 Gene3D G3DSA:3.40.50.300 2 197 2.2E-90 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12940 4fbd4064b8c2989868afbf2922147492 198 PANTHER PTHR11055 5 197 3.5E-126 T 22-04-2016 TOLA_RS12940 4fbd4064b8c2989868afbf2922147492 198 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 23 195 39.018 T 22-04-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: REACT_13433|UniPathway: UPA00140 TOLA_RS12940 4fbd4064b8c2989868afbf2922147492 198 Pfam PF01583 Adenylylsulphate kinase 25 178 3.0E-73 T 22-04-2016 TOLA_RS01260 cff8cf037c4550fcd54667f623f61733 433 PANTHER PTHR23502:SF63 28 410 3.0E-80 T 22-04-2016 TOLA_RS01260 cff8cf037c4550fcd54667f623f61733 433 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 35 405 7.6E-61 T 22-04-2016 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 TOLA_RS01260 cff8cf037c4550fcd54667f623f61733 433 Gene3D G3DSA:1.20.1250.20 248 415 3.6E-5 T 22-04-2016 TOLA_RS01260 cff8cf037c4550fcd54667f623f61733 433 SUPERFAMILY SSF103473 23 415 1.03E-60 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS01260 cff8cf037c4550fcd54667f623f61733 433 PANTHER PTHR23502 28 410 3.0E-80 T 22-04-2016 TOLA_RS01260 cff8cf037c4550fcd54667f623f61733 433 Gene3D G3DSA:1.20.1250.20 36 221 7.9E-31 T 22-04-2016 TOLA_RS01260 cff8cf037c4550fcd54667f623f61733 433 Pfam PF07690 Major Facilitator Superfamily 42 380 3.2E-47 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS11195 210a8c7ad2a01b99de6ec97458e7d376 295 PANTHER PTHR40572 16 287 1.0E-51 T 22-04-2016 TOLA_RS11195 210a8c7ad2a01b99de6ec97458e7d376 295 SMART SM00047 127 269 3.1E-4 T 22-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 TOLA_RS11195 210a8c7ad2a01b99de6ec97458e7d376 295 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 154 280 2.9E-18 T 22-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 TOLA_RS05095 e1f8d55472ef4b829e60a57e06243250 366 TIGRFAM TIGR03169 Nterm_to_SelD: pyridine nucleotide-disulfide oxidoreductase family protein 4 363 7.0E-101 T 22-04-2016 IPR017584 Pyridine nucleotide-disulphide oxidoreductase family protein, N-terminal TOLA_RS05095 e1f8d55472ef4b829e60a57e06243250 366 SUPERFAMILY SSF51905 134 310 2.65E-25 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05095 e1f8d55472ef4b829e60a57e06243250 366 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 5.3E-7 T 22-04-2016 TOLA_RS05095 e1f8d55472ef4b829e60a57e06243250 366 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.3E-7 T 22-04-2016 TOLA_RS05095 e1f8d55472ef4b829e60a57e06243250 366 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 5.3E-7 T 22-04-2016 TOLA_RS05095 e1f8d55472ef4b829e60a57e06243250 366 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 292 1.6E-27 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05095 e1f8d55472ef4b829e60a57e06243250 366 PANTHER PTHR22912 148 308 9.7E-13 T 22-04-2016 TOLA_RS05095 e1f8d55472ef4b829e60a57e06243250 366 SUPERFAMILY SSF51905 1 172 5.33E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05095 e1f8d55472ef4b829e60a57e06243250 366 Gene3D G3DSA:3.50.50.60 141 305 4.8E-24 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05095 e1f8d55472ef4b829e60a57e06243250 366 Gene3D G3DSA:3.50.50.60 2 119 1.4E-14 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04470 be12a195794097c301bb3911c0c03a1f 229 Pfam PF00072 Response regulator receiver domain 4 113 4.0E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS04470 be12a195794097c301bb3911c0c03a1f 229 PANTHER PTHR26402:SF292 2 227 2.2E-84 T 22-04-2016 TOLA_RS04470 be12a195794097c301bb3911c0c03a1f 229 Gene3D G3DSA:3.40.50.2300 1 126 1.0E-40 T 22-04-2016 TOLA_RS04470 be12a195794097c301bb3911c0c03a1f 229 PANTHER PTHR26402 2 227 2.2E-84 T 22-04-2016 TOLA_RS04470 be12a195794097c301bb3911c0c03a1f 229 SUPERFAMILY SSF46894 132 228 3.4E-24 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TOLA_RS04470 be12a195794097c301bb3911c0c03a1f 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 4.8E-20 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS04470 be12a195794097c301bb3911c0c03a1f 229 Gene3D G3DSA:1.10.10.10 130 228 1.2E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS04470 be12a195794097c301bb3911c0c03a1f 229 SMART SM00448 2 112 1.4E-43 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS04470 be12a195794097c301bb3911c0c03a1f 229 SUPERFAMILY SSF52172 1 127 3.27E-42 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS04470 be12a195794097c301bb3911c0c03a1f 229 SMART SM00862 150 226 3.5E-22 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS07010 37b476f48e8f2eb93772796ad5cc71ff 520 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS07010 37b476f48e8f2eb93772796ad5cc71ff 520 SUPERFAMILY SSF52540 8 231 1.2E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07010 37b476f48e8f2eb93772796ad5cc71ff 520 Pfam PF00005 ABC transporter 25 172 1.1E-26 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS07010 37b476f48e8f2eb93772796ad5cc71ff 520 Pfam PF00005 ABC transporter 278 436 1.4E-16 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS07010 37b476f48e8f2eb93772796ad5cc71ff 520 PANTHER PTHR24220:SF239 10 389 4.5E-169 T 22-04-2016 TOLA_RS07010 37b476f48e8f2eb93772796ad5cc71ff 520 PANTHER PTHR24220 10 389 4.5E-169 T 22-04-2016 TOLA_RS07010 37b476f48e8f2eb93772796ad5cc71ff 520 SUPERFAMILY SSF52540 261 494 5.23E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07010 37b476f48e8f2eb93772796ad5cc71ff 520 SMART SM00382 33 221 1.5E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS07010 37b476f48e8f2eb93772796ad5cc71ff 520 SMART SM00382 286 485 0.74 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS07010 37b476f48e8f2eb93772796ad5cc71ff 520 Gene3D G3DSA:3.40.50.300 6 237 4.1E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07010 37b476f48e8f2eb93772796ad5cc71ff 520 Gene3D G3DSA:3.40.50.300 262 500 8.5E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PIRSF PIRSF016599 1 484 1.1E-192 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 Gene3D G3DSA:3.40.630.10 2 181 1.2E-98 T 22-04-2016 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 Gene3D G3DSA:3.40.630.10 396 483 1.2E-98 T 22-04-2016 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PANTHER PTHR11014 204 278 1.3E-167 T 22-04-2016 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PANTHER PTHR11014 1 185 1.3E-167 T 22-04-2016 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PANTHER PTHR11014 329 486 1.3E-167 T 22-04-2016 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PRINTS PR00934 X-His dipeptidase (M25) signature 101 119 1.2E-80 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PRINTS PR00934 X-His dipeptidase (M25) signature 80 99 1.2E-80 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PRINTS PR00934 X-His dipeptidase (M25) signature 427 443 1.2E-80 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PRINTS PR00934 X-His dipeptidase (M25) signature 250 269 1.2E-80 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PRINTS PR00934 X-His dipeptidase (M25) signature 362 380 1.2E-80 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PRINTS PR00934 X-His dipeptidase (M25) signature 206 223 1.2E-80 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PRINTS PR00934 X-His dipeptidase (M25) signature 159 177 1.2E-80 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PRINTS PR00934 X-His dipeptidase (M25) signature 449 471 1.2E-80 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PRINTS PR00934 X-His dipeptidase (M25) signature 135 152 1.2E-80 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 SUPERFAMILY SSF53187 396 481 2.02E-59 T 22-04-2016 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 SUPERFAMILY SSF53187 12 182 2.02E-59 T 22-04-2016 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PANTHER PTHR11014:SF54 204 278 1.3E-167 T 22-04-2016 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PANTHER PTHR11014:SF54 1 185 1.3E-167 T 22-04-2016 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 PANTHER PTHR11014:SF54 329 486 1.3E-167 T 22-04-2016 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 Pfam PF01546 Peptidase family M20/M25/M40 72 478 5.3E-25 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 8 481 7.0E-170 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS04120 9dcd759e0ccdbb2e1f1f2b133e94e781 486 Pfam PF07687 Peptidase dimerisation domain 209 292 3.8E-8 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain TOLA_RS04395 e513629e792e7a1809163e41aa3e8e9f 219 PANTHER PTHR10516:SF316 1 83 3.0E-43 T 22-04-2016 TOLA_RS04395 e513629e792e7a1809163e41aa3e8e9f 219 PANTHER PTHR10516:SF316 128 195 3.0E-43 T 22-04-2016 TOLA_RS04395 e513629e792e7a1809163e41aa3e8e9f 219 SUPERFAMILY SSF54534 3 139 2.75E-31 T 22-04-2016 TOLA_RS04395 e513629e792e7a1809163e41aa3e8e9f 219 PANTHER PTHR10516 1 83 3.0E-43 T 22-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type TOLA_RS04395 e513629e792e7a1809163e41aa3e8e9f 219 PANTHER PTHR10516 128 195 3.0E-43 T 22-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type TOLA_RS04395 e513629e792e7a1809163e41aa3e8e9f 219 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 85 1.1E-6 T 22-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 TOLA_RS04395 e513629e792e7a1809163e41aa3e8e9f 219 Gene3D G3DSA:3.10.50.40 3 80 3.5E-14 T 22-04-2016 TOLA_RS04395 e513629e792e7a1809163e41aa3e8e9f 219 Gene3D G3DSA:3.10.50.40 125 139 3.5E-14 T 22-04-2016 TOLA_RS01390 2cdc36fa932e823fa1c4f69b8c81fbfe 104 ProDom PD030876 UPF0265 YEEX HELIX ALPHA BFL460 UNCHARACTERIZED FN0411 HI1168 VPA1226 BCR 1 96 3.0E-29 T 22-04-2016 IPR007458 Protein of unknown function DUF496 TOLA_RS01390 2cdc36fa932e823fa1c4f69b8c81fbfe 104 PANTHER PTHR39591 1 93 7.3E-44 T 22-04-2016 TOLA_RS01390 2cdc36fa932e823fa1c4f69b8c81fbfe 104 Hamap MF_00683 UPF0265 protein YeeX [yeeX]. 1 95 22.303 T 22-04-2016 IPR007458 Protein of unknown function DUF496 TOLA_RS01390 2cdc36fa932e823fa1c4f69b8c81fbfe 104 Pfam PF04363 Protein of unknown function (DUF496) 1 92 6.8E-43 T 22-04-2016 IPR007458 Protein of unknown function DUF496 TOLA_RS01390 2cdc36fa932e823fa1c4f69b8c81fbfe 104 PIRSF PIRSF028773 1 102 1.0E-43 T 22-04-2016 IPR007458 Protein of unknown function DUF496 TOLA_RS13810 84bba63e111b1162125ff28f7994525f 223 Pfam PF01618 MotA/TolQ/ExbB proton channel family 75 202 3.3E-43 T 22-04-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 TOLA_RS13810 84bba63e111b1162125ff28f7994525f 223 PANTHER PTHR30625:SF3 1 219 4.1E-74 T 22-04-2016 TOLA_RS13810 84bba63e111b1162125ff28f7994525f 223 PANTHER PTHR30625 1 219 4.1E-74 T 22-04-2016 TOLA_RS13810 84bba63e111b1162125ff28f7994525f 223 TIGRFAM TIGR02796 tolQ: protein TolQ 2 216 9.9E-92 T 22-04-2016 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 TOLA_RS08155 1d3271197e1580aa8b68627e909c4948 413 Gene3D G3DSA:3.40.50.300 261 393 4.0E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08155 1d3271197e1580aa8b68627e909c4948 413 SUPERFAMILY SSF52540 261 379 2.98E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08155 1d3271197e1580aa8b68627e909c4948 413 Pfam PF13671 AAA domain 262 391 2.5E-18 T 22-04-2016 TOLA_RS08155 1d3271197e1580aa8b68627e909c4948 413 SUPERFAMILY SSF109604 41 144 3.18E-10 T 22-04-2016 TOLA_RS08155 1d3271197e1580aa8b68627e909c4948 413 Gene3D G3DSA:1.10.3210.10 46 142 7.5E-5 T 22-04-2016 IPR006674 HD domain TOLA_RS10335 7b0122506a6ca86fb008328c50595bb9 219 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 213 1.9E-56 T 22-04-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS10335 7b0122506a6ca86fb008328c50595bb9 219 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 217 32.063 T 22-04-2016 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS10335 7b0122506a6ca86fb008328c50595bb9 219 SUPERFAMILY SSF100950 1 147 4.34E-47 T 22-04-2016 TOLA_RS10335 7b0122506a6ca86fb008328c50595bb9 219 PANTHER PTHR11934:SF11 1 219 1.3E-129 T 22-04-2016 TOLA_RS10335 7b0122506a6ca86fb008328c50595bb9 219 Gene3D G3DSA:3.40.50.1360 4 140 7.9E-59 T 22-04-2016 TOLA_RS10335 7b0122506a6ca86fb008328c50595bb9 219 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 214 1.2E-66 T 22-04-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS10335 7b0122506a6ca86fb008328c50595bb9 219 PANTHER PTHR11934 1 219 1.3E-129 T 22-04-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS10335 7b0122506a6ca86fb008328c50595bb9 219 Gene3D G3DSA:3.30.70.260 141 196 3.1E-26 T 22-04-2016 TOLA_RS10335 7b0122506a6ca86fb008328c50595bb9 219 SUPERFAMILY SSF75445 127 198 7.98E-22 T 22-04-2016 TOLA_RS09995 5b426e42fdf96f51d68ad1f85ab652e2 230 PANTHER PTHR28047 3 227 7.1E-51 T 22-04-2016 TOLA_RS09995 5b426e42fdf96f51d68ad1f85ab652e2 230 PANTHER PTHR28047:SF1 3 227 7.1E-51 T 22-04-2016 TOLA_RS16040 8a7d5bafe26277cedbafd07cb8a921d8 811 Pfam PF01295 Adenylate cyclase, class-I 205 800 1.3E-246 T 22-04-2016 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 TOLA_RS16040 8a7d5bafe26277cedbafd07cb8a921d8 811 Pfam PF12633 Adenylate cyclase NT domain 1 177 4.6E-68 T 22-04-2016 IPR024685 Adenylate cyclase class-I, N-terminal domain KEGG: 00230+4.6.1.1 TOLA_RS16040 8a7d5bafe26277cedbafd07cb8a921d8 811 ProSitePatterns PS01093 Adenylate cyclase class-I signature 2. 578 592 - T 22-04-2016 IPR024686 Adenylate cyclase class-I, conserved site KEGG: 00230+4.6.1.1 TOLA_RS16040 8a7d5bafe26277cedbafd07cb8a921d8 811 PIRSF PIRSF001444 1 810 0.0 T 22-04-2016 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 TOLA_RS16040 8a7d5bafe26277cedbafd07cb8a921d8 811 PANTHER PTHR38760 1 802 1.2E-283 T 22-04-2016 TOLA_RS16040 8a7d5bafe26277cedbafd07cb8a921d8 811 ProSitePatterns PS01092 Adenylate cyclase class-I signature 1. 219 230 - T 22-04-2016 IPR024686 Adenylate cyclase class-I, conserved site KEGG: 00230+4.6.1.1 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 Gene3D G3DSA:2.40.30.10 301 393 6.7E-47 T 22-04-2016 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 3.5E-58 T 22-04-2016 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 SUPERFAMILY SSF52540 6 219 2.06E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 SUPERFAMILY SSF50447 205 301 1.24E-30 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.5E-24 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.5E-24 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.5E-24 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.5E-24 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.5E-24 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 145 3.7E-14 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 Gene3D G3DSA:2.40.30.10 209 298 4.8E-37 T 22-04-2016 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 PANTHER PTHR23115 1 393 4.4E-304 T 22-04-2016 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 Pfam PF03144 Elongation factor Tu domain 2 225 293 3.7E-17 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 393 6.2E-238 T 22-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 Pfam PF03143 Elongation factor Tu C-terminal domain 298 392 1.7E-33 T 22-04-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 Gene3D G3DSA:3.40.50.300 3 208 3.3E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 SUPERFAMILY SSF50465 298 393 3.17E-36 T 22-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 PANTHER PTHR23115:SF151 1 393 4.4E-304 T 22-04-2016 TOLA_RS14205 1ae6cf54d864c70d8a82a0d7c6161617 394 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 394 61.47 T 22-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 2 526 51.436 T 22-04-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 2 528 0.0 T 22-04-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 57 72 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 Pfam PF00009 Elongation factor Tu GTP binding domain 11 276 2.3E-45 T 22-04-2016 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 Gene3D G3DSA:3.30.70.870 394 463 4.4E-14 T 22-04-2016 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 PANTHER PTHR23115:SF69 250 471 1.3E-251 T 22-04-2016 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 PANTHER PTHR23115:SF69 1 183 1.3E-251 T 22-04-2016 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 Pfam PF03144 Elongation factor Tu domain 2 313 379 2.6E-10 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 SUPERFAMILY SSF52540 8 276 2.93E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 PRINTS PR00315 GTP-binding elongation factor signature 13 26 6.6E-11 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 PRINTS PR00315 GTP-binding elongation factor signature 84 94 6.6E-11 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 PRINTS PR00315 GTP-binding elongation factor signature 64 72 6.6E-11 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 PRINTS PR00315 GTP-binding elongation factor signature 136 145 6.6E-11 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 PRINTS PR00315 GTP-binding elongation factor signature 100 111 6.6E-11 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 SUPERFAMILY SSF54980 392 467 1.01E-17 T 22-04-2016 IPR009022 Elongation factor G, III-V domain TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 162 1.1E-18 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 Pfam PF16658 Class II release factor RF3, C-terminal domain 386 513 2.0E-45 T 22-04-2016 IPR032090 Peptide chain release factor 3, C-terminal TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 PANTHER PTHR23115 250 471 1.3E-251 T 22-04-2016 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 PANTHER PTHR23115 1 183 1.3E-251 T 22-04-2016 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 SUPERFAMILY SSF50447 261 392 1.19E-29 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 Gene3D G3DSA:2.40.30.10 292 393 3.9E-26 T 22-04-2016 TOLA_RS13235 a87ab3fbed5411abc07f5a643bc2842e 528 Gene3D G3DSA:3.40.50.300 6 281 2.6E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 Gene3D G3DSA:3.40.50.300 15 232 7.3E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 Gene3D G3DSA:2.40.30.10 240 326 8.6E-21 T 22-04-2016 TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 SUPERFAMILY SSF50465 330 433 1.39E-31 T 22-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 PRINTS PR00315 GTP-binding elongation factor signature 89 97 4.823225E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 PRINTS PR00315 GTP-binding elongation factor signature 109 119 4.823225E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 PRINTS PR00315 GTP-binding elongation factor signature 28 41 4.823225E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 PRINTS PR00315 GTP-binding elongation factor signature 125 136 4.823225E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 PRINTS PR00315 GTP-binding elongation factor signature 162 171 4.823225E-13 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 SUPERFAMILY SSF50447 238 326 1.79E-26 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 33 210 3.2E-14 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 SUPERFAMILY SSF52540 19 234 3.72E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 18 471 52.736 T 22-04-2016 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 27 432 1.3E-196 T 22-04-2016 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 82 97 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 Pfam PF00009 Elongation factor Tu GTP binding domain 26 225 2.5E-43 T 22-04-2016 TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 PANTHER PTHR23115 7 53 2.4E-80 T 22-04-2016 TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 PANTHER PTHR23115 73 361 2.4E-80 T 22-04-2016 TOLA_RS12945 fc63039e36dec0f6916cad8b2c36b53d 472 Gene3D G3DSA:2.40.30.10 330 434 9.9E-6 T 22-04-2016 TOLA_RS08625 1370586e3eab249b33e843ab8b888b48 347 PIRSF PIRSF036411 1 344 1.4E-110 T 22-04-2016 IPR009221 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, bifunctional PduO TOLA_RS08625 1370586e3eab249b33e843ab8b888b48 347 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 157 3.0E-41 T 22-04-2016 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 TOLA_RS08625 1370586e3eab249b33e843ab8b888b48 347 Gene3D G3DSA:1.20.1200.10 12 176 1.6E-55 T 22-04-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 TOLA_RS08625 1370586e3eab249b33e843ab8b888b48 347 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 176 2.0E-52 T 22-04-2016 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 TOLA_RS08625 1370586e3eab249b33e843ab8b888b48 347 PANTHER PTHR12213:SF0 1 195 7.1E-70 T 22-04-2016 TOLA_RS08625 1370586e3eab249b33e843ab8b888b48 347 SUPERFAMILY SSF143744 211 340 2.62E-36 T 22-04-2016 TOLA_RS08625 1370586e3eab249b33e843ab8b888b48 347 Pfam PF03928 Haem-degrading 213 338 9.6E-27 T 22-04-2016 IPR005624 Haem-degrading TOLA_RS08625 1370586e3eab249b33e843ab8b888b48 347 Pfam PF01923 Cobalamin adenosyltransferase 3 167 2.0E-55 T 22-04-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 TOLA_RS08625 1370586e3eab249b33e843ab8b888b48 347 PANTHER PTHR12213 1 195 7.1E-70 T 22-04-2016 TOLA_RS08625 1370586e3eab249b33e843ab8b888b48 347 SUPERFAMILY SSF89028 1 175 1.73E-53 T 22-04-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 TOLA_RS04900 1b682d4506058a3fd36bb84d4087944b 565 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 306 342 7.8E-4 T 22-04-2016 IPR001434 Domain of unknown function DUF11 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 PRINTS PR00046 Major sigma-70 factor signature 404 417 6.4E-31 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 PRINTS PR00046 Major sigma-70 factor signature 573 588 6.4E-31 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 PRINTS PR00046 Major sigma-70 factor signature 552 564 6.4E-31 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 PRINTS PR00046 Major sigma-70 factor signature 588 599 6.4E-31 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 PRINTS PR00046 Major sigma-70 factor signature 428 436 6.4E-31 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 404 417 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 376 612 1.4E-121 T 22-04-2016 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 SUPERFAMILY SSF88946 114 447 1.24E-94 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 SUPERFAMILY SSF88659 453 526 8.07E-22 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 Pfam PF04539 Sigma-70 region 3 459 535 3.5E-30 T 22-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 SUPERFAMILY SSF88659 510 612 1.7E-25 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 Pfam PF03979 Sigma-70 factor, region 1.1 5 79 6.9E-30 T 22-04-2016 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 Pfam PF04542 Sigma-70 region 2 380 449 1.7E-21 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 PANTHER PTHR30603 327 613 4.4E-252 T 22-04-2016 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 PANTHER PTHR30603 10 151 4.4E-252 T 22-04-2016 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 PANTHER PTHR30603:SF0 327 613 4.4E-252 T 22-04-2016 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 PANTHER PTHR30603:SF0 10 151 4.4E-252 T 22-04-2016 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 Pfam PF04546 Sigma-70, non-essential region 138 349 4.9E-68 T 22-04-2016 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 Gene3D G3DSA:1.10.601.10 111 449 1.7E-133 T 22-04-2016 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 573 599 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 Gene3D G3DSA:1.10.10.10 453 504 2.3E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 4 613 46.169 T 22-04-2016 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 Pfam PF00140 Sigma-70 factor, region 1.2 97 127 1.4E-12 T 22-04-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 376 601 4.2E-37 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 Pfam PF04545 Sigma-70, region 4 548 601 1.3E-18 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS13590 f76f87cea9a342f65ce8d674893d94ae 614 Gene3D G3DSA:1.10.10.10 545 613 2.2E-32 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS12630 8d00b204dd1d595b0ea11a5f72d7b0de 97 SUPERFAMILY SSF47413 23 89 9.57E-17 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS12630 8d00b204dd1d595b0ea11a5f72d7b0de 97 SMART SM00530 28 83 7.5E-13 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS12630 8d00b204dd1d595b0ea11a5f72d7b0de 97 PANTHER PTHR10245 25 84 9.3E-14 T 22-04-2016 TOLA_RS12630 8d00b204dd1d595b0ea11a5f72d7b0de 97 Gene3D G3DSA:1.10.260.40 23 88 3.2E-19 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS12630 8d00b204dd1d595b0ea11a5f72d7b0de 97 Pfam PF13560 Helix-turn-helix domain 24 83 5.1E-12 T 22-04-2016 TOLA_RS14490 b78934c4c09f7e7cd1042e3b784cb90b 156 SUPERFAMILY SSF75217 1 154 9.42E-49 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases TOLA_RS14490 b78934c4c09f7e7cd1042e3b784cb90b 156 PIRSF PIRSF004505 1 155 1.8E-40 T 22-04-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS14490 b78934c4c09f7e7cd1042e3b784cb90b 156 PANTHER PTHR33603 1 155 4.1E-69 T 22-04-2016 TOLA_RS14490 b78934c4c09f7e7cd1042e3b784cb90b 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 27.033 T 22-04-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS14490 b78934c4c09f7e7cd1042e3b784cb90b 156 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 156 7.3E-80 T 22-04-2016 IPR016051 Ribosomal RNA large subunit methyltransferase H GO:0005737|GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS14490 b78934c4c09f7e7cd1042e3b784cb90b 156 Gene3D G3DSA:3.40.1280.10 1 155 1.3E-53 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TOLA_RS14490 b78934c4c09f7e7cd1042e3b784cb90b 156 PANTHER PTHR33603:SF1 1 155 4.1E-69 T 22-04-2016 TOLA_RS14490 b78934c4c09f7e7cd1042e3b784cb90b 156 Pfam PF02590 Predicted SPOUT methyltransferase 1 154 2.0E-47 T 22-04-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 SUPERFAMILY SSF50249 363 447 2.98E-22 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 SUPERFAMILY SSF50249 1 112 3.35E-17 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 PANTHER PTHR10724 1 514 3.7E-273 T 22-04-2016 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 9.8E-235 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 SUPERFAMILY SSF50249 255 364 8.58E-29 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 Pfam PF00575 S1 RNA binding domain 449 520 7.4E-16 T 22-04-2016 IPR003029 S1 domain GO:0003676 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 Pfam PF00575 S1 RNA binding domain 189 260 3.2E-21 T 22-04-2016 IPR003029 S1 domain GO:0003676 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 Pfam PF00575 S1 RNA binding domain 275 347 1.5E-21 T 22-04-2016 IPR003029 S1 domain GO:0003676 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 Pfam PF00575 S1 RNA binding domain 361 434 9.7E-22 T 22-04-2016 IPR003029 S1 domain GO:0003676 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 Pfam PF00575 S1 RNA binding domain 107 171 5.5E-8 T 22-04-2016 IPR003029 S1 domain GO:0003676 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 SUPERFAMILY SSF50249 429 534 9.7E-23 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 SUPERFAMILY SSF50249 88 174 2.39E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 PIRSF PIRSF002111 1 534 9.4E-220 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 PRINTS PR00681 Ribosomal protein S1 signature 108 124 4.4E-97 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 PRINTS PR00681 Ribosomal protein S1 signature 21 39 4.4E-97 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 PRINTS PR00681 Ribosomal protein S1 signature 126 143 4.4E-97 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 PRINTS PR00681 Ribosomal protein S1 signature 84 103 4.4E-97 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 PRINTS PR00681 Ribosomal protein S1 signature 212 233 4.4E-97 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 PRINTS PR00681 Ribosomal protein S1 signature 330 348 4.4E-97 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 PRINTS PR00681 Ribosomal protein S1 signature 155 175 4.4E-97 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 PRINTS PR00681 Ribosomal protein S1 signature 39 53 4.4E-97 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 PRINTS PR00681 Ribosomal protein S1 signature 290 309 4.4E-97 T 22-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 SMART SM00316 103 171 1.1E-7 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 SMART SM00316 449 520 9.8E-20 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 SMART SM00316 275 347 6.7E-28 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 SMART SM00316 190 260 9.4E-28 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 SMART SM00316 362 434 7.1E-23 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 SMART SM00316 19 87 6.5E-4 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 Gene3D G3DSA:2.40.50.140 21 101 8.2E-10 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 Gene3D G3DSA:2.40.50.140 192 274 1.7E-30 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 SUPERFAMILY SSF50249 190 277 8.95E-27 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 Gene3D G3DSA:2.40.50.140 444 532 2.5E-20 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 Gene3D G3DSA:2.40.50.140 275 357 4.9E-30 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 Gene3D G3DSA:2.40.50.140 358 443 1.8E-26 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 PANTHER PTHR10724:SF6 1 514 3.7E-273 T 22-04-2016 TOLA_RS07940 230d2b18d8240ec2bcdbeae0c0872250 556 Gene3D G3DSA:2.40.50.140 102 172 3.4E-15 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS01915 25a5ff128872e2f3ad5b91ff413f8e02 220 Pfam PF12019 Type II transport protein GspH 46 203 3.3E-13 T 22-04-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 TOLA_RS01915 25a5ff128872e2f3ad5b91ff413f8e02 220 Gene3D G3DSA:3.55.40.10 42 214 2.0E-43 T 22-04-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 TOLA_RS01915 25a5ff128872e2f3ad5b91ff413f8e02 220 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 26 1.7E-5 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS01915 25a5ff128872e2f3ad5b91ff413f8e02 220 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 24 2.7E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS01915 25a5ff128872e2f3ad5b91ff413f8e02 220 PRINTS PR00885 Bacterial general secretion pathway protein H signature 3 17 2.0E-6 T 22-04-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 TOLA_RS01915 25a5ff128872e2f3ad5b91ff413f8e02 220 PRINTS PR00885 Bacterial general secretion pathway protein H signature 18 32 2.0E-6 T 22-04-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 TOLA_RS01915 25a5ff128872e2f3ad5b91ff413f8e02 220 SUPERFAMILY SSF54523 8 104 5.1E-9 T 22-04-2016 TOLA_RS01915 25a5ff128872e2f3ad5b91ff413f8e02 220 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 6 206 2.0E-22 T 22-04-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 TOLA_RS09110 62af3f5e076d013cbc72f0349826dfdc 325 SUPERFAMILY SSF52283 1 134 4.54E-25 T 22-04-2016 TOLA_RS09110 62af3f5e076d013cbc72f0349826dfdc 325 Gene3D G3DSA:3.40.50.720 2 114 2.8E-26 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09110 62af3f5e076d013cbc72f0349826dfdc 325 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 22-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TOLA_RS09110 62af3f5e076d013cbc72f0349826dfdc 325 PANTHER PTHR10996 1 320 5.6E-130 T 22-04-2016 TOLA_RS09110 62af3f5e076d013cbc72f0349826dfdc 325 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 148 176 - T 22-04-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TOLA_RS09110 62af3f5e076d013cbc72f0349826dfdc 325 SUPERFAMILY SSF51735 102 287 1.94E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09110 62af3f5e076d013cbc72f0349826dfdc 325 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 319 2.0E-24 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 TOLA_RS09110 62af3f5e076d013cbc72f0349826dfdc 325 Gene3D G3DSA:3.40.50.720 115 290 1.2E-64 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09110 62af3f5e076d013cbc72f0349826dfdc 325 PANTHER PTHR10996:SF118 1 320 5.6E-130 T 22-04-2016 TOLA_RS09110 62af3f5e076d013cbc72f0349826dfdc 325 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 287 2.1E-61 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TOLA_RS03405 e372726da5dc5ee507136e079b811f49 297 Pfam PF01106 NifU-like domain 223 287 2.3E-19 T 22-04-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 TOLA_RS03405 e372726da5dc5ee507136e079b811f49 297 SUPERFAMILY SSF117916 217 291 1.94E-18 T 22-04-2016 TOLA_RS03405 e372726da5dc5ee507136e079b811f49 297 PANTHER PTHR10093:SF1 1 174 2.3E-66 T 22-04-2016 TOLA_RS03405 e372726da5dc5ee507136e079b811f49 297 PIRSF PIRSF000375 1 290 3.9E-119 T 22-04-2016 IPR016217 Nitrogen fixation, NifU TOLA_RS03405 e372726da5dc5ee507136e079b811f49 297 Pfam PF04324 BFD-like [2Fe-2S] binding domain 135 184 1.9E-16 T 22-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain TOLA_RS03405 e372726da5dc5ee507136e079b811f49 297 Pfam PF01592 NifU-like N terminal domain 3 125 3.3E-52 T 22-04-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 TOLA_RS03405 e372726da5dc5ee507136e079b811f49 297 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 231 288 2.0E-16 T 22-04-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 TOLA_RS03405 e372726da5dc5ee507136e079b811f49 297 TIGRFAM TIGR02000 NifU_proper: Fe-S cluster assembly protein NifU 1 288 3.2E-138 T 22-04-2016 IPR010238 NIF system FeS cluster assembly, NifU GO:0005506|GO:0016226|GO:0051536 TOLA_RS03405 e372726da5dc5ee507136e079b811f49 297 Gene3D G3DSA:3.90.1010.10 3 127 3.1E-42 T 22-04-2016 TOLA_RS03405 e372726da5dc5ee507136e079b811f49 297 PANTHER PTHR10093 1 174 2.3E-66 T 22-04-2016 TOLA_RS03405 e372726da5dc5ee507136e079b811f49 297 SUPERFAMILY SSF82649 2 131 7.33E-43 T 22-04-2016 TOLA_RS08220 01a34e23b8bba805ac21444f0e8997f7 198 Pfam PF11951 Fungal specific transcription factor domain 71 189 1.6E-5 T 22-04-2016 IPR021858 Fungal transcription factor TOLA_RS12860 fe3d0aebfc9d07a44906f4cb3a86f8b1 149 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 2.0E-73 T 22-04-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TOLA_RS12860 fe3d0aebfc9d07a44906f4cb3a86f8b1 149 PANTHER PTHR30455 2 149 5.4E-73 T 22-04-2016 TOLA_RS12860 fe3d0aebfc9d07a44906f4cb3a86f8b1 149 PANTHER PTHR30455:SF2 2 149 5.4E-73 T 22-04-2016 TOLA_RS12860 fe3d0aebfc9d07a44906f4cb3a86f8b1 149 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 149 89.763 T 22-04-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TOLA_RS12860 fe3d0aebfc9d07a44906f4cb3a86f8b1 149 Pfam PF03477 ATP cone domain 50 136 3.4E-16 T 22-04-2016 IPR005144 ATP-cone domain TOLA_RS03415 e264beadc3c474eaa88b32b4329925db 97 SUPERFAMILY SSF143120 9 56 1.7E-6 T 22-04-2016 TOLA_RS03415 e264beadc3c474eaa88b32b4329925db 97 PANTHER PTHR33713:SF5 1 92 8.7E-23 T 22-04-2016 TOLA_RS03415 e264beadc3c474eaa88b32b4329925db 97 PANTHER PTHR33713 1 92 8.7E-23 T 22-04-2016 TOLA_RS03415 e264beadc3c474eaa88b32b4329925db 97 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 7 60 1.5E-7 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TOLA_RS00885 1e2f2625221e9572485348003b3171e5 478 Pfam PF00367 phosphotransferase system, EIIB 12 43 1.4E-12 T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS00885 1e2f2625221e9572485348003b3171e5 478 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 7 460 6.2E-206 T 22-04-2016 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 TOLA_RS00885 1e2f2625221e9572485348003b3171e5 478 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 21 38 - T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS00885 1e2f2625221e9572485348003b3171e5 478 Pfam PF02378 Phosphotransferase system, EIIC 112 404 3.2E-30 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS00885 1e2f2625221e9572485348003b3171e5 478 PANTHER PTHR30175 1 477 6.2E-256 T 22-04-2016 TOLA_RS00885 1e2f2625221e9572485348003b3171e5 478 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 30 111 1.0E-14 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS00885 1e2f2625221e9572485348003b3171e5 478 Gene3D G3DSA:3.30.1360.60 5 82 3.0E-23 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS00885 1e2f2625221e9572485348003b3171e5 478 SUPERFAMILY SSF55604 10 81 1.44E-19 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS00885 1e2f2625221e9572485348003b3171e5 478 PANTHER PTHR30175:SF4 1 477 6.2E-256 T 22-04-2016 TOLA_RS16115 0926367ac48581e9b1feefec2927450e 302 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 45 221 3.2E-57 T 22-04-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TOLA_RS16115 0926367ac48581e9b1feefec2927450e 302 PANTHER PTHR33375 1 295 1.3E-82 T 22-04-2016 TOLA_RS16115 0926367ac48581e9b1feefec2927450e 302 SMART SM00470 48 138 4.0E-34 T 22-04-2016 IPR003115 ParB/Sulfiredoxin TOLA_RS16115 0926367ac48581e9b1feefec2927450e 302 SUPERFAMILY SSF110849 47 182 4.6E-34 T 22-04-2016 IPR003115 ParB/Sulfiredoxin TOLA_RS16115 0926367ac48581e9b1feefec2927450e 302 PANTHER PTHR33375:SF1 1 295 1.3E-82 T 22-04-2016 TOLA_RS16115 0926367ac48581e9b1feefec2927450e 302 Pfam PF02195 ParB-like nuclease domain 50 138 1.5E-28 T 22-04-2016 IPR003115 ParB/Sulfiredoxin TOLA_RS16115 0926367ac48581e9b1feefec2927450e 302 Gene3D G3DSA:3.90.1530.10 39 140 3.0E-40 T 22-04-2016 TOLA_RS16115 0926367ac48581e9b1feefec2927450e 302 Gene3D G3DSA:1.10.260.40 141 185 1.5E-4 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 SUPERFAMILY SSF46977 427 528 2.62E-33 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.7E-10 T 22-04-2016 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 2.7E-10 T 22-04-2016 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 8 521 6.4E-211 T 22-04-2016 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 PANTHER PTHR11632:SF27 6 534 4.8E-265 T 22-04-2016 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 SUPERFAMILY SSF56425 239 354 8.52E-43 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 Gene3D G3DSA:3.50.50.60 350 410 2.6E-99 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 Gene3D G3DSA:3.50.50.60 2 244 2.6E-99 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 Pfam PF02910 Fumarate reductase flavoprotein C-term 442 526 3.9E-16 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 Gene3D G3DSA:3.90.700.10 245 349 2.9E-38 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 371 378 2.5E-5 T 22-04-2016 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 2.5E-5 T 22-04-2016 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 SUPERFAMILY SSF51905 4 256 6.2E-72 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 SUPERFAMILY SSF51905 357 448 6.2E-72 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 Pfam PF00890 FAD binding domain 10 393 6.0E-101 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 Gene3D G3DSA:1.20.58.100 421 523 1.9E-35 T 22-04-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 TOLA_RS04325 3cab4f41bd6360a627b50e74b0587519 537 PANTHER PTHR11632 6 534 4.8E-265 T 22-04-2016 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 PANTHER PTHR32282 1 944 0.0 T 22-04-2016 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 939 22.945 T 22-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Pfam PF00005 ABC transporter 805 859 5.8E-5 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 ProSitePatterns PS00211 ABC transporters family signature. 829 843 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Gene3D G3DSA:1.20.1580.10 693 819 1.4E-54 T 22-04-2016 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 SUPERFAMILY SSF52540 618 908 3.9E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01230 5912cabd65363d358af1134508f29841 944 PANTHER PTHR32282:SF2 1 944 0.0 T 22-04-2016 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 3 924 0.0 T 22-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Gene3D G3DSA:3.40.50.300 478 597 2.2E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Gene3D G3DSA:3.40.50.300 820 940 1.2E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Gene3D G3DSA:3.40.50.300 613 669 1.2E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Gene3D G3DSA:3.40.50.300 2 51 2.2E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01230 5912cabd65363d358af1134508f29841 944 SUPERFAMILY SSF52540 3 204 4.64E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01230 5912cabd65363d358af1134508f29841 944 SUPERFAMILY SSF52540 430 569 4.64E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Gene3D G3DSA:1.10.8.280 286 406 1.8E-43 T 22-04-2016 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Gene3D G3DSA:1.20.1580.10 251 284 1.3E-55 T 22-04-2016 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Gene3D G3DSA:1.20.1580.10 407 477 1.3E-55 T 22-04-2016 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Gene3D G3DSA:1.20.1580.10 91 129 1.3E-55 T 22-04-2016 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Gene3D G3DSA:3.30.1490.20 200 241 4.4E-26 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS01230 5912cabd65363d358af1134508f29841 944 Gene3D G3DSA:3.30.1490.20 130 153 4.4E-26 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS08685 c99cee85a0e47053887476691bda181e 332 SUPERFAMILY SSF53822 66 332 1.22E-60 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS08685 c99cee85a0e47053887476691bda181e 332 SUPERFAMILY SSF47413 4 55 3.38E-11 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS08685 c99cee85a0e47053887476691bda181e 332 SMART SM00354 5 75 6.7E-7 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS08685 c99cee85a0e47053887476691bda181e 332 Pfam PF13377 Periplasmic binding protein-like domain 173 332 8.8E-33 T 22-04-2016 TOLA_RS08685 c99cee85a0e47053887476691bda181e 332 Gene3D G3DSA:1.10.260.40 5 51 2.8E-16 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS08685 c99cee85a0e47053887476691bda181e 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 4.2E-13 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS08685 c99cee85a0e47053887476691bda181e 332 Gene3D G3DSA:3.40.50.2300 174 332 1.9E-51 T 22-04-2016 TOLA_RS08685 c99cee85a0e47053887476691bda181e 332 PANTHER PTHR30146:SF4 4 332 6.7E-81 T 22-04-2016 TOLA_RS08685 c99cee85a0e47053887476691bda181e 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS08685 c99cee85a0e47053887476691bda181e 332 Gene3D G3DSA:3.40.50.2300 66 173 1.2E-12 T 22-04-2016 TOLA_RS08685 c99cee85a0e47053887476691bda181e 332 PANTHER PTHR30146 4 332 6.7E-81 T 22-04-2016 TOLA_RS12780 3db7a9b85c4863e3ab544d5fce1d7f4b 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 308 2.7E-31 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS12780 3db7a9b85c4863e3ab544d5fce1d7f4b 311 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 8 68 1.3E-10 T 22-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TOLA_RS12780 3db7a9b85c4863e3ab544d5fce1d7f4b 311 PANTHER PTHR30465 6 310 8.6E-191 T 22-04-2016 TOLA_RS12780 3db7a9b85c4863e3ab544d5fce1d7f4b 311 SUPERFAMILY SSF161098 92 294 5.89E-27 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS12780 3db7a9b85c4863e3ab544d5fce1d7f4b 311 PANTHER PTHR30465:SF67 6 310 8.6E-191 T 22-04-2016 TOLA_RS12780 3db7a9b85c4863e3ab544d5fce1d7f4b 311 Gene3D G3DSA:1.10.3720.10 90 306 1.3E-29 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 Pfam PF00890 FAD binding domain 483 905 2.4E-86 T 22-04-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 Gene3D G3DSA:3.20.20.70 4 342 3.3E-100 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 Pfam PF04205 FMN-binding domain 398 462 1.1E-5 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 SUPERFAMILY SSF56425 719 865 5.38E-42 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 Gene3D G3DSA:3.50.50.60 861 921 7.9E-98 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 Gene3D G3DSA:3.50.50.60 480 713 7.9E-98 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 Gene3D G3DSA:3.90.700.10 719 856 2.3E-38 T 22-04-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 SMART SM00900 383 465 0.002 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 TIGRFAM TIGR01813 flavo_cyto_c: flavocytochrome c 483 916 3.9E-149 T 22-04-2016 IPR010960 Flavocytochrome c GO:0000104|GO:0055114 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 484 503 1.4E-6 T 22-04-2016 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 869 891 1.4E-6 T 22-04-2016 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 339 4.1E-74 T 22-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 SUPERFAMILY SSF51905 478 736 3.64E-58 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 SUPERFAMILY SSF51905 864 922 3.64E-58 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 SUPERFAMILY SSF51395 5 349 2.69E-97 T 22-04-2016 TOLA_RS12995 ff793e85ff72a5afc78d1a924354d993 926 PANTHER PTHR11632 482 924 2.2E-137 T 22-04-2016 TOLA_RS13735 742d9d165d5f1c223488705ea05a8d87 294 PIRSF PIRSF016020 3 294 7.1E-56 T 22-04-2016 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 TOLA_RS13735 742d9d165d5f1c223488705ea05a8d87 294 Gene3D G3DSA:2.70.98.10 10 292 1.6E-78 T 22-04-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 TOLA_RS13735 742d9d165d5f1c223488705ea05a8d87 294 SUPERFAMILY SSF74650 20 291 1.26E-59 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 TOLA_RS13735 742d9d165d5f1c223488705ea05a8d87 294 PANTHER PTHR11122 21 292 6.3E-74 T 22-04-2016 TOLA_RS13735 742d9d165d5f1c223488705ea05a8d87 294 PANTHER PTHR11122:SF14 21 292 6.3E-74 T 22-04-2016 TOLA_RS13735 742d9d165d5f1c223488705ea05a8d87 294 Pfam PF01263 Aldose 1-epimerase 29 291 2.4E-42 T 22-04-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 TOLA_RS00500 01593e146f2f35961942e67a50f4fd33 260 Pfam PF00696 Amino acid kinase family 7 237 3.2E-36 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS00500 01593e146f2f35961942e67a50f4fd33 260 Hamap MF_00082_B Acetylglutamate kinase [argB]. 3 260 25.282 T 22-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS00500 01593e146f2f35961942e67a50f4fd33 260 TIGRFAM TIGR00761 argB: acetylglutamate kinase 7 226 6.8E-59 T 22-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS00500 01593e146f2f35961942e67a50f4fd33 260 Gene3D G3DSA:3.40.1160.10 7 258 1.4E-72 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS00500 01593e146f2f35961942e67a50f4fd33 260 PANTHER PTHR23342 6 258 7.9E-66 T 22-04-2016 TOLA_RS00500 01593e146f2f35961942e67a50f4fd33 260 SUPERFAMILY SSF53633 7 257 6.81E-56 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS00500 01593e146f2f35961942e67a50f4fd33 260 PIRSF PIRSF000728 1 260 7.3E-65 T 22-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS14690 5f98b162f72cf84532760f8975e813ed 145 SMART SM00226 5 142 3.1E-48 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily TOLA_RS14690 5f98b162f72cf84532760f8975e813ed 145 SUPERFAMILY SSF52788 1 143 1.7E-40 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily TOLA_RS14690 5f98b162f72cf84532760f8975e813ed 145 Gene3D G3DSA:3.40.50.270 3 144 4.7E-41 T 22-04-2016 TOLA_RS14690 5f98b162f72cf84532760f8975e813ed 145 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 140 7.9E-37 T 22-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily TOLA_RS14690 5f98b162f72cf84532760f8975e813ed 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 77 92 1.7E-24 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TOLA_RS14690 5f98b162f72cf84532760f8975e813ed 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 43 59 1.7E-24 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TOLA_RS14690 5f98b162f72cf84532760f8975e813ed 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 114 129 1.7E-24 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TOLA_RS14690 5f98b162f72cf84532760f8975e813ed 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 7 24 1.7E-24 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TOLA_RS14690 5f98b162f72cf84532760f8975e813ed 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 99 112 1.7E-24 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TOLA_RS14690 5f98b162f72cf84532760f8975e813ed 145 PANTHER PTHR11717:SF20 1 144 1.3E-53 T 22-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TOLA_RS14690 5f98b162f72cf84532760f8975e813ed 145 PANTHER PTHR11717 1 144 1.3E-53 T 22-04-2016 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 Pfam PF05193 Peptidase M16 inactive domain 184 360 8.4E-17 T 22-04-2016 IPR007863 Peptidase M16, C-terminal TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 Pfam PF05193 Peptidase M16 inactive domain 652 823 1.1E-7 T 22-04-2016 IPR007863 Peptidase M16, C-terminal TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 Pfam PF00675 Insulinase (Peptidase family M16) 23 160 7.2E-34 T 22-04-2016 IPR011765 Peptidase M16, N-terminal TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 Pfam PF16187 Middle or third domain of peptidase_M16 372 647 3.0E-78 T 22-04-2016 IPR032632 Peptidase M16, middle/third domain TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 SUPERFAMILY SSF63411 235 462 8.21E-73 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 SUPERFAMILY SSF63411 707 901 6.46E-42 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 SUPERFAMILY SSF63411 475 700 1.57E-52 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 44 67 - T 22-04-2016 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 SUPERFAMILY SSF63411 3 228 6.42E-54 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 Gene3D G3DSA:3.30.830.10 710 924 5.0E-47 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 Gene3D G3DSA:3.30.830.10 477 709 4.9E-58 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 PANTHER PTHR11851:SF131 380 901 0.0 T 22-04-2016 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 PANTHER PTHR11851:SF131 1 363 0.0 T 22-04-2016 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 Gene3D G3DSA:3.30.830.10 5 231 1.3E-67 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 Gene3D G3DSA:3.30.830.10 244 476 1.3E-70 T 22-04-2016 IPR011237 Peptidase M16 domain GO:0046872 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 PANTHER PTHR11851 380 901 0.0 T 22-04-2016 TOLA_RS11090 43ddfa6f4f30a9e9d49d48b7a1a5fce4 929 PANTHER PTHR11851 1 363 0.0 T 22-04-2016 TOLA_RS01630 44de8d6a2bb223823279850712c001c5 174 PANTHER PTHR36570:SF2 5 168 8.0E-56 T 22-04-2016 TOLA_RS01630 44de8d6a2bb223823279850712c001c5 174 PANTHER PTHR36570 5 168 8.0E-56 T 22-04-2016 TOLA_RS01630 44de8d6a2bb223823279850712c001c5 174 Gene3D G3DSA:1.20.1550.10 3 169 1.4E-56 T 22-04-2016 IPR023380 Disulphide bond formation protein DsbB-like domain TOLA_RS01630 44de8d6a2bb223823279850712c001c5 174 SUPERFAMILY SSF158442 15 161 2.09E-38 T 22-04-2016 TOLA_RS01630 44de8d6a2bb223823279850712c001c5 174 Pfam PF02600 Disulfide bond formation protein DsbB 12 160 2.6E-41 T 22-04-2016 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 TOLA_RS01630 44de8d6a2bb223823279850712c001c5 174 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 7 168 19.872 T 22-04-2016 IPR022920 Disulphide bond formation protein DsbB TOLA_RS07520 1a00c1a3de9a29c3fd51a55cd2863d68 186 Pfam PF12464 Maltose acetyltransferase 9 59 6.6E-14 T 22-04-2016 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 TOLA_RS07520 1a00c1a3de9a29c3fd51a55cd2863d68 186 PANTHER PTHR23416 3 186 8.4E-79 T 22-04-2016 TOLA_RS07520 1a00c1a3de9a29c3fd51a55cd2863d68 186 SMART SM01266 6 60 7.3E-20 T 22-04-2016 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 TOLA_RS07520 1a00c1a3de9a29c3fd51a55cd2863d68 186 PANTHER PTHR23416:SF58 3 186 8.4E-79 T 22-04-2016 TOLA_RS07520 1a00c1a3de9a29c3fd51a55cd2863d68 186 SUPERFAMILY SSF51161 4 184 9.43E-51 T 22-04-2016 IPR011004 Trimeric LpxA-like TOLA_RS07520 1a00c1a3de9a29c3fd51a55cd2863d68 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 164 4.0E-10 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS07520 1a00c1a3de9a29c3fd51a55cd2863d68 186 Gene3D G3DSA:2.160.10.10 3 184 3.6E-59 T 22-04-2016 TOLA_RS15910 c2c3e51779ed9777b8cdb1d1de646631 342 SUPERFAMILY SSF53822 61 340 1.25E-62 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS15910 c2c3e51779ed9777b8cdb1d1de646631 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 4.3E-21 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS15910 c2c3e51779ed9777b8cdb1d1de646631 342 Gene3D G3DSA:3.40.50.2300 54 181 8.3E-30 T 22-04-2016 TOLA_RS15910 c2c3e51779ed9777b8cdb1d1de646631 342 Gene3D G3DSA:1.10.260.40 2 53 6.1E-27 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS15910 c2c3e51779ed9777b8cdb1d1de646631 342 PANTHER PTHR30146:SF48 1 341 8.6E-108 T 22-04-2016 TOLA_RS15910 c2c3e51779ed9777b8cdb1d1de646631 342 SMART SM00354 1 71 5.0E-35 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS15910 c2c3e51779ed9777b8cdb1d1de646631 342 PANTHER PTHR30146 1 341 8.6E-108 T 22-04-2016 TOLA_RS15910 c2c3e51779ed9777b8cdb1d1de646631 342 Gene3D G3DSA:3.40.50.2300 182 319 1.1E-46 T 22-04-2016 TOLA_RS15910 c2c3e51779ed9777b8cdb1d1de646631 342 SUPERFAMILY SSF47413 1 59 6.29E-19 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS15910 c2c3e51779ed9777b8cdb1d1de646631 342 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.5E-5 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS15910 c2c3e51779ed9777b8cdb1d1de646631 342 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.5E-5 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS15910 c2c3e51779ed9777b8cdb1d1de646631 342 Pfam PF13377 Periplasmic binding protein-like domain 177 339 1.4E-31 T 22-04-2016 TOLA_RS07050 a59af9b8e1a2c319a78583c366d692c2 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.3E-15 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07050 a59af9b8e1a2c319a78583c366d692c2 318 SUPERFAMILY SSF46785 7 92 9.52E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07050 a59af9b8e1a2c319a78583c366d692c2 318 Pfam PF03466 LysR substrate binding domain 93 290 9.3E-15 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS07050 a59af9b8e1a2c319a78583c366d692c2 318 PANTHER PTHR30126 6 307 1.7E-104 T 22-04-2016 TOLA_RS07050 a59af9b8e1a2c319a78583c366d692c2 318 PANTHER PTHR30126:SF19 6 307 1.7E-104 T 22-04-2016 TOLA_RS07050 a59af9b8e1a2c319a78583c366d692c2 318 Gene3D G3DSA:1.10.10.10 7 84 1.9E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07050 a59af9b8e1a2c319a78583c366d692c2 318 Gene3D G3DSA:3.40.190.10 166 255 4.1E-8 T 22-04-2016 TOLA_RS07050 a59af9b8e1a2c319a78583c366d692c2 318 SUPERFAMILY SSF53850 93 290 7.6E-19 T 22-04-2016 TOLA_RS14265 b0725edef2cd5b0576812b637ac5929b 234 Gene3D G3DSA:3.30.190.20 17 68 9.3E-45 T 22-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 TOLA_RS14265 b0725edef2cd5b0576812b637ac5929b 234 Gene3D G3DSA:3.30.190.20 161 225 9.3E-45 T 22-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 TOLA_RS14265 b0725edef2cd5b0576812b637ac5929b 234 SUPERFAMILY SSF56808 6 225 2.22E-80 T 22-04-2016 IPR023674 Ribosomal protein L1-like TOLA_RS14265 b0725edef2cd5b0576812b637ac5929b 234 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 22-04-2016 IPR023673 Ribosomal protein L1, conserved site TOLA_RS14265 b0725edef2cd5b0576812b637ac5929b 234 PANTHER PTHR23105 19 232 4.7E-79 T 22-04-2016 TOLA_RS14265 b0725edef2cd5b0576812b637ac5929b 234 Gene3D G3DSA:3.40.50.790 69 159 6.6E-41 T 22-04-2016 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich TOLA_RS14265 b0725edef2cd5b0576812b637ac5929b 234 PIRSF PIRSF002155 1 227 6.6E-77 T 22-04-2016 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 TOLA_RS14265 b0725edef2cd5b0576812b637ac5929b 234 PANTHER PTHR23105:SF5 19 232 4.7E-79 T 22-04-2016 TOLA_RS14265 b0725edef2cd5b0576812b637ac5929b 234 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.664 T 22-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TOLA_RS14265 b0725edef2cd5b0576812b637ac5929b 234 Pfam PF00687 Ribosomal protein L1p/L10e family 30 219 7.5E-50 T 22-04-2016 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein TOLA_RS14265 b0725edef2cd5b0576812b637ac5929b 234 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 1.0E-105 T 22-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.8E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.8E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.8E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.8E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.8E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 2.8E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.6E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.6E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.6E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PANTHER PTHR24322 151 183 2.8E-74 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PANTHER PTHR24322 10 135 2.8E-74 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 182 9.7E-5 T 22-04-2016 TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 241 8.1E-69 T 22-04-2016 TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PANTHER PTHR24322:SF635 151 183 2.8E-74 T 22-04-2016 TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 PANTHER PTHR24322:SF635 10 135 2.8E-74 T 22-04-2016 TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 Gene3D G3DSA:3.40.50.720 2 243 2.2E-88 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 242 2.1E-101 T 22-04-2016 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 SUPERFAMILY SSF51735 4 243 2.49E-86 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS11130 f67501088e83dfaf118f49085792ec4f 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TOLA_RS01875 51b5a5b1e7a6b07bfc2486f2d39b5d97 199 SUPERFAMILY SSF46689 9 82 4.82E-20 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS01875 51b5a5b1e7a6b07bfc2486f2d39b5d97 199 Gene3D G3DSA:1.10.357.10 9 192 3.8E-36 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 TOLA_RS01875 51b5a5b1e7a6b07bfc2486f2d39b5d97 199 Pfam PF13977 Bacterial transcriptional repressor 101 190 4.2E-8 T 22-04-2016 TOLA_RS01875 51b5a5b1e7a6b07bfc2486f2d39b5d97 199 PANTHER PTHR30055 2 199 2.2E-29 T 22-04-2016 TOLA_RS01875 51b5a5b1e7a6b07bfc2486f2d39b5d97 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.6E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS01875 51b5a5b1e7a6b07bfc2486f2d39b5d97 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.6E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS01875 51b5a5b1e7a6b07bfc2486f2d39b5d97 199 SUPERFAMILY SSF48498 101 184 1.93E-8 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TOLA_RS01875 51b5a5b1e7a6b07bfc2486f2d39b5d97 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 5.1E-16 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS02590 103076e5c6f2973c6772027718e128c9 270 Gene3D G3DSA:1.20.1080.10 23 250 1.7E-59 T 22-04-2016 IPR023271 Aquaporin-like TOLA_RS02590 103076e5c6f2973c6772027718e128c9 270 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 158 168 - T 22-04-2016 IPR024002 Formate/nitrite transporter, conserved site TOLA_RS02590 103076e5c6f2973c6772027718e128c9 270 Pfam PF01226 Formate/nitrite transporter 18 248 1.9E-55 T 22-04-2016 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 TOLA_RS02590 103076e5c6f2973c6772027718e128c9 270 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 21 251 3.1E-71 T 22-04-2016 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 TOLA_RS02590 103076e5c6f2973c6772027718e128c9 270 PANTHER PTHR30520:SF5 1 256 8.1E-111 T 22-04-2016 TOLA_RS02590 103076e5c6f2973c6772027718e128c9 270 PANTHER PTHR30520 1 256 8.1E-111 T 22-04-2016 TOLA_RS15415 d53aa229b125e312c619509992e55430 450 PIRSF PIRSF000850 2 450 3.5E-181 T 22-04-2016 IPR016270 Phospholipase D, phosphatidylserine synthase type GO:0008654|GO:0016780 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 TOLA_RS15415 d53aa229b125e312c619509992e55430 450 SUPERFAMILY SSF56024 248 401 9.1E-23 T 22-04-2016 TOLA_RS15415 d53aa229b125e312c619509992e55430 450 PANTHER PTHR12586 8 449 1.0E-195 T 22-04-2016 IPR016270 Phospholipase D, phosphatidylserine synthase type GO:0008654|GO:0016780 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 TOLA_RS15415 d53aa229b125e312c619509992e55430 450 Gene3D G3DSA:3.30.870.10 247 412 4.5E-16 T 22-04-2016 TOLA_RS15415 d53aa229b125e312c619509992e55430 450 Gene3D G3DSA:3.30.870.10 21 192 5.9E-14 T 22-04-2016 TOLA_RS15415 d53aa229b125e312c619509992e55430 450 PANTHER PTHR12586:SF3 8 449 1.0E-195 T 22-04-2016 TOLA_RS15415 d53aa229b125e312c619509992e55430 450 Pfam PF13091 PLD-like domain 256 393 9.2E-20 T 22-04-2016 IPR025202 Phospholipase D-like domain TOLA_RS15415 d53aa229b125e312c619509992e55430 450 SUPERFAMILY SSF56024 19 200 1.19E-22 T 22-04-2016 TOLA_RS15415 d53aa229b125e312c619509992e55430 450 SMART SM00155 130 156 6.6 T 22-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 TOLA_RS15415 d53aa229b125e312c619509992e55430 450 SMART SM00155 351 378 0.45 T 22-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 TOLA_RS16000 76fa78f25059acb756660ddfbb211e89 94 PANTHER PTHR40275:SF1 2 94 3.8E-25 T 22-04-2016 TOLA_RS16000 76fa78f25059acb756660ddfbb211e89 94 SUPERFAMILY SSF47413 29 90 3.17E-8 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS16000 76fa78f25059acb756660ddfbb211e89 94 PANTHER PTHR40275 2 94 3.8E-25 T 22-04-2016 TOLA_RS16000 76fa78f25059acb756660ddfbb211e89 94 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 6 92 1.5E-37 T 22-04-2016 IPR014057 Addiction module antidote protein, HI1420 TOLA_RS06445 fcd38d9c8d8bf759623b7a4d3c738648 433 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 23 421 1.3E-100 T 22-04-2016 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 TOLA_RS06445 fcd38d9c8d8bf759623b7a4d3c738648 433 PANTHER PTHR30026:SF4 1 433 4.6E-71 T 22-04-2016 TOLA_RS06445 fcd38d9c8d8bf759623b7a4d3c738648 433 Pfam PF02321 Outer membrane efflux protein 26 213 1.5E-23 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS06445 fcd38d9c8d8bf759623b7a4d3c738648 433 Pfam PF02321 Outer membrane efflux protein 233 417 2.6E-21 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS06445 fcd38d9c8d8bf759623b7a4d3c738648 433 PANTHER PTHR30026 1 433 4.6E-71 T 22-04-2016 TOLA_RS06445 fcd38d9c8d8bf759623b7a4d3c738648 433 Gene3D G3DSA:1.20.1600.10 20 421 2.6E-63 T 22-04-2016 TOLA_RS06445 fcd38d9c8d8bf759623b7a4d3c738648 433 SUPERFAMILY SSF56954 4 421 4.45E-78 T 22-04-2016 TOLA_RS08840 40efa72a35a2aa07c99f5ce39aba8c14 200 PIRSF PIRSF000495 1 200 9.7E-68 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 TOLA_RS08840 40efa72a35a2aa07c99f5ce39aba8c14 200 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 2 200 35.276 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 TOLA_RS08840 40efa72a35a2aa07c99f5ce39aba8c14 200 SUPERFAMILY SSF52317 4 199 9.17E-54 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS08840 40efa72a35a2aa07c99f5ce39aba8c14 200 Gene3D G3DSA:3.40.50.880 2 200 2.4E-71 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS08840 40efa72a35a2aa07c99f5ce39aba8c14 200 PANTHER PTHR21235 5 200 7.6E-82 T 22-04-2016 TOLA_RS08840 40efa72a35a2aa07c99f5ce39aba8c14 200 Pfam PF00117 Glutamine amidotransferase class-I 6 198 4.7E-19 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 TOLA_RS08840 40efa72a35a2aa07c99f5ce39aba8c14 200 PANTHER PTHR21235:SF1 5 200 7.6E-82 T 22-04-2016 TOLA_RS08840 40efa72a35a2aa07c99f5ce39aba8c14 200 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 200 5.5E-69 T 22-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 TOLA_RS11680 b79472587f3aab5186028f95dd21ca5a 264 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 263 41.756 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 TOLA_RS11680 b79472587f3aab5186028f95dd21ca5a 264 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 3 263 1.7E-109 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 TOLA_RS11680 b79472587f3aab5186028f95dd21ca5a 264 Gene3D G3DSA:3.20.20.60 2 263 5.9E-112 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS11680 b79472587f3aab5186028f95dd21ca5a 264 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 258 2.1E-109 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 TOLA_RS11680 b79472587f3aab5186028f95dd21ca5a 264 PIRSF PIRSF000388 1 264 2.2E-100 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 TOLA_RS11680 b79472587f3aab5186028f95dd21ca5a 264 PANTHER PTHR20881 1 264 1.0E-156 T 22-04-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 TOLA_RS11680 b79472587f3aab5186028f95dd21ca5a 264 PANTHER PTHR20881:SF3 1 264 1.0E-156 T 22-04-2016 TOLA_RS11680 b79472587f3aab5186028f95dd21ca5a 264 SUPERFAMILY SSF51621 4 263 4.71E-105 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS00035 e70cce17082fe543d4ea7777f3859154 413 PANTHER PTHR11751 11 411 1.2E-145 T 22-04-2016 TOLA_RS00035 e70cce17082fe543d4ea7777f3859154 413 PANTHER PTHR11751:SF419 11 411 1.2E-145 T 22-04-2016 TOLA_RS00035 e70cce17082fe543d4ea7777f3859154 413 SUPERFAMILY SSF53383 16 412 4.26E-68 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS00035 e70cce17082fe543d4ea7777f3859154 413 Pfam PF00155 Aminotransferase class I and II 67 401 5.0E-28 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TOLA_RS00035 e70cce17082fe543d4ea7777f3859154 413 Gene3D G3DSA:3.90.1150.10 268 412 2.0E-20 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS00035 e70cce17082fe543d4ea7777f3859154 413 Gene3D G3DSA:3.40.640.10 63 267 2.7E-42 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS00920 776455f830c42d922c7cd05a772efe1e 277 Gene3D G3DSA:3.40.190.10 116 233 4.1E-18 T 22-04-2016 TOLA_RS00920 776455f830c42d922c7cd05a772efe1e 277 SMART SM00062 37 274 2.6E-30 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS00920 776455f830c42d922c7cd05a772efe1e 277 PANTHER PTHR18966 33 272 2.5E-23 T 22-04-2016 TOLA_RS00920 776455f830c42d922c7cd05a772efe1e 277 PANTHER PTHR18966:SF191 33 272 2.5E-23 T 22-04-2016 TOLA_RS00920 776455f830c42d922c7cd05a772efe1e 277 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 272 5.5E-46 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS00920 776455f830c42d922c7cd05a772efe1e 277 Gene3D G3DSA:3.40.190.10 34 115 7.0E-31 T 22-04-2016 TOLA_RS00920 776455f830c42d922c7cd05a772efe1e 277 Gene3D G3DSA:3.40.190.10 234 275 7.0E-31 T 22-04-2016 TOLA_RS00920 776455f830c42d922c7cd05a772efe1e 277 SUPERFAMILY SSF53850 9 275 1.45E-49 T 22-04-2016 TOLA_RS05320 ed201624252b93d94ce062cc00fda9f8 275 PANTHER PTHR22789:SF4 76 274 3.8E-61 T 22-04-2016 TOLA_RS05320 ed201624252b93d94ce062cc00fda9f8 275 PANTHER PTHR22789:SF4 3 43 3.8E-61 T 22-04-2016 TOLA_RS05320 ed201624252b93d94ce062cc00fda9f8 275 SMART SM01007 15 249 2.2E-16 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal TOLA_RS05320 ed201624252b93d94ce062cc00fda9f8 275 Gene3D G3DSA:3.40.225.10 12 274 5.9E-68 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal TOLA_RS05320 ed201624252b93d94ce062cc00fda9f8 275 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 16 248 7.2E-26 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal TOLA_RS05320 ed201624252b93d94ce062cc00fda9f8 275 PANTHER PTHR22789 76 274 3.8E-61 T 22-04-2016 TOLA_RS05320 ed201624252b93d94ce062cc00fda9f8 275 PANTHER PTHR22789 3 43 3.8E-61 T 22-04-2016 TOLA_RS05320 ed201624252b93d94ce062cc00fda9f8 275 SUPERFAMILY SSF53639 7 273 3.73E-47 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 SMART SM00052 403 639 3.7E-12 T 22-04-2016 IPR001633 EAL domain TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 Pfam PF00990 Diguanylate cyclase, GGDEF domain 237 386 5.9E-13 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 Gene3D G3DSA:3.30.70.270 239 394 2.1E-19 T 22-04-2016 TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 234 389 6.8E-11 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 Pfam PF00563 EAL domain 410 632 2.5E-39 T 22-04-2016 IPR001633 EAL domain TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 SMART SM00267 226 394 4.3E-10 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 PANTHER PTHR33121:SF10 219 229 1.6E-23 T 22-04-2016 TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 PANTHER PTHR33121:SF10 356 632 1.6E-23 T 22-04-2016 TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 Gene3D G3DSA:3.20.20.450 407 633 2.1E-36 T 22-04-2016 IPR001633 EAL domain TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 SUPERFAMILY SSF141868 411 633 3.53E-36 T 22-04-2016 IPR001633 EAL domain TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 SUPERFAMILY SSF55073 243 389 4.71E-18 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 Pfam PF16448 LapD/MoxY periplasmic domain 24 146 5.0E-37 T 22-04-2016 IPR032244 LapD/MoxY, periplasmic domain TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 PANTHER PTHR33121 219 229 1.6E-23 T 22-04-2016 TOLA_RS06455 0b200f65dd2561d66b5e187e6f0547f9 640 PANTHER PTHR33121 356 632 1.6E-23 T 22-04-2016 TOLA_RS08535 9b27033d3bd790cca9bed1181be66467 378 SUPERFAMILY SSF111342 8 291 6.67E-84 T 22-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 TOLA_RS08535 9b27033d3bd790cca9bed1181be66467 378 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 24 367 7.6E-87 T 22-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 TOLA_RS08535 9b27033d3bd790cca9bed1181be66467 378 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 17 367 30.007 T 22-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 TOLA_RS08535 9b27033d3bd790cca9bed1181be66467 378 Gene3D G3DSA:3.30.2110.10 19 188 2.5E-52 T 22-04-2016 TOLA_RS08535 9b27033d3bd790cca9bed1181be66467 378 PIRSF PIRSF026782 13 374 3.4E-127 T 22-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 TOLA_RS08535 9b27033d3bd790cca9bed1181be66467 378 Pfam PF01888 CbiD 18 273 7.7E-93 T 22-04-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 TOLA_RS08535 9b27033d3bd790cca9bed1181be66467 378 PANTHER PTHR35863:SF1 6 378 3.1E-121 T 22-04-2016 TOLA_RS08535 9b27033d3bd790cca9bed1181be66467 378 PANTHER PTHR35863 6 378 3.1E-121 T 22-04-2016 TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 SUPERFAMILY SSF50249 65 127 4.71E-14 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 Pfam PF09285 Elongation factor P, C-terminal 130 186 5.3E-20 T 22-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 60 4.0E-21 T 22-04-2016 IPR013185 Translation elongation factor, KOW-like UniPathway: UPA00345 TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 122 2.1E-16 T 22-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 SUPERFAMILY SSF50249 130 187 1.63E-12 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 Hamap MF_00141 Elongation factor P [efp]. 1 187 46.599 T 22-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 SUPERFAMILY SSF50104 1 63 2.61E-17 T 22-04-2016 IPR008991 Translation protein SH3-like domain TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 Gene3D G3DSA:2.30.30.30 1 63 5.1E-22 T 22-04-2016 IPR014722 Ribosomal protein L2 domain 2 TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 Gene3D G3DSA:2.40.50.140 129 187 1.2E-21 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 TIGRFAM TIGR00038 efp: translation elongation factor P 4 187 3.5E-60 T 22-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 SMART SM01185 67 122 2.2E-19 T 22-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 PANTHER PTHR30053 1 187 2.5E-66 T 22-04-2016 TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 PIRSF PIRSF005901 1 187 1.2E-53 T 22-04-2016 IPR020599 Translation elongation factor P/YeiP UniPathway: UPA00345 TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 Gene3D G3DSA:2.40.50.140 65 127 4.3E-19 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS16140 a73aa0f7228e8c388925556b24beb3ed 187 SMART SM00841 130 186 3.9E-22 T 22-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 TOLA_RS06670 c6ae361e2d9b1b528d96cbce23281eb8 134 SUPERFAMILY SSF55811 4 113 4.47E-26 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS06670 c6ae361e2d9b1b528d96cbce23281eb8 134 Gene3D G3DSA:3.90.79.10 3 114 5.7E-29 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS06670 c6ae361e2d9b1b528d96cbce23281eb8 134 PRINTS PR00502 NUDIX hydrolase family signature 34 48 5.0E-7 T 22-04-2016 IPR020476 NUDIX hydrolase TOLA_RS06670 c6ae361e2d9b1b528d96cbce23281eb8 134 PRINTS PR00502 NUDIX hydrolase family signature 48 63 5.0E-7 T 22-04-2016 IPR020476 NUDIX hydrolase TOLA_RS06670 c6ae361e2d9b1b528d96cbce23281eb8 134 Pfam PF00293 NUDIX domain 8 111 2.3E-16 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TOLA_RS06670 c6ae361e2d9b1b528d96cbce23281eb8 134 PANTHER PTHR22769:SF14 5 112 2.4E-19 T 22-04-2016 TOLA_RS06670 c6ae361e2d9b1b528d96cbce23281eb8 134 PANTHER PTHR22769 5 112 2.4E-19 T 22-04-2016 TOLA_RS07915 23f5ef437dcc8644c177cee502c87fbc 200 Gene3D G3DSA:1.20.1540.10 21 197 2.5E-18 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TOLA_RS07915 23f5ef437dcc8644c177cee502c87fbc 200 Pfam PF01694 Rhomboid family 51 197 4.5E-15 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TOLA_RS07915 23f5ef437dcc8644c177cee502c87fbc 200 SUPERFAMILY SSF144091 18 198 1.44E-24 T 22-04-2016 TOLA_RS07915 23f5ef437dcc8644c177cee502c87fbc 200 TIGRFAM TIGR03902 rhom_GG_sort: rhombosortase 43 193 4.2E-40 T 22-04-2016 IPR023826 Rhomboid-like serine protease, proteobacteria TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 PANTHER PTHR10359:SF18 1 213 4.9E-92 T 22-04-2016 TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 22-04-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 SUPERFAMILY SSF48150 2 208 1.88E-74 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 Gene3D G3DSA:1.10.1670.10 123 208 6.1E-36 T 22-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 PANTHER PTHR10359 1 213 4.9E-92 T 22-04-2016 TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 22-04-2016 IPR004035 Endonuclease III, iron-sulphur binding site TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 Pfam PF00633 Helix-hairpin-helix motif 100 127 3.1E-7 T 22-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 4.4E-4 T 22-04-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 TIGRFAM TIGR01083 nth: endonuclease III 4 194 3.3E-88 T 22-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 Hamap MF_00942 Endonuclease III [nth]. 1 209 37.391 T 22-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 165 1.9E-20 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 PIRSF PIRSF001435 1 212 5.3E-54 T 22-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 SMART SM00525 186 206 1.6E-5 T 22-04-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 SMART SM00478 38 185 2.6E-55 T 22-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 TOLA_RS07365 c28828a91bd21faffa87a8327bbbfe69 213 Gene3D G3DSA:1.10.340.30 23 122 3.1E-34 T 22-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 TOLA_RS10040 ce7b80d63d354320102d5b0da649615f 310 PANTHER PTHR32196 27 309 1.0E-73 T 22-04-2016 TOLA_RS10040 ce7b80d63d354320102d5b0da649615f 310 Gene3D G3DSA:3.40.50.2300 24 149 6.8E-29 T 22-04-2016 TOLA_RS10040 ce7b80d63d354320102d5b0da649615f 310 Gene3D G3DSA:3.40.50.2300 150 310 1.4E-45 T 22-04-2016 TOLA_RS10040 ce7b80d63d354320102d5b0da649615f 310 PANTHER PTHR32196:SF9 27 309 1.0E-73 T 22-04-2016 TOLA_RS10040 ce7b80d63d354320102d5b0da649615f 310 Pfam PF13407 Periplasmic binding protein domain 27 287 1.2E-54 T 22-04-2016 IPR025997 Periplasmic binding protein TOLA_RS10040 ce7b80d63d354320102d5b0da649615f 310 SUPERFAMILY SSF53822 27 310 4.54E-69 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS10230 d2166a83789bcf86e944ffc61b99d7af 143 Gene3D G3DSA:3.30.70.141 1 140 1.9E-60 T 22-04-2016 TOLA_RS10230 d2166a83789bcf86e944ffc61b99d7af 143 PANTHER PTHR11349 1 143 3.9E-77 T 22-04-2016 TOLA_RS10230 d2166a83789bcf86e944ffc61b99d7af 143 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 35.138 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS10230 d2166a83789bcf86e944ffc61b99d7af 143 SUPERFAMILY SSF54919 1 141 2.49E-59 T 22-04-2016 TOLA_RS10230 d2166a83789bcf86e944ffc61b99d7af 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 3.0E-39 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS10230 d2166a83789bcf86e944ffc61b99d7af 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 3.0E-39 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS10230 d2166a83789bcf86e944ffc61b99d7af 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 3.0E-39 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS10230 d2166a83789bcf86e944ffc61b99d7af 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 3.0E-39 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS10230 d2166a83789bcf86e944ffc61b99d7af 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 3.0E-39 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS10230 d2166a83789bcf86e944ffc61b99d7af 143 Pfam PF00334 Nucleoside diphosphate kinase 4 138 1.4E-56 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS10230 d2166a83789bcf86e944ffc61b99d7af 143 SMART SM00562 3 140 1.0E-83 T 22-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TOLA_RS00525 11b5ae13d752109b38956915b4acd6e6 201 SUPERFAMILY SSF52166 10 200 1.16E-73 T 22-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 TOLA_RS00525 11b5ae13d752109b38956915b4acd6e6 201 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 6 201 34.476 T 22-04-2016 IPR013005 50S ribosomal protein uL4 TOLA_RS00525 11b5ae13d752109b38956915b4acd6e6 201 Gene3D G3DSA:3.40.1370.10 53 201 1.6E-59 T 22-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 TOLA_RS00525 11b5ae13d752109b38956915b4acd6e6 201 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 13 198 4.3E-76 T 22-04-2016 IPR013005 50S ribosomal protein uL4 TOLA_RS00525 11b5ae13d752109b38956915b4acd6e6 201 PANTHER PTHR10746 11 200 5.2E-93 T 22-04-2016 IPR013005 50S ribosomal protein uL4 TOLA_RS00525 11b5ae13d752109b38956915b4acd6e6 201 Pfam PF00573 Ribosomal protein L4/L1 family 13 198 6.6E-66 T 22-04-2016 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 3 609 2.3E-226 T 22-04-2016 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PANTHER PTHR22773 1 568 9.7E-224 T 22-04-2016 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 226 247 8.8E-55 T 22-04-2016 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 158 179 8.8E-55 T 22-04-2016 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 83 108 8.8E-55 T 22-04-2016 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 111 131 8.8E-55 T 22-04-2016 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 316 328 8.8E-55 T 22-04-2016 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 248 274 8.8E-55 T 22-04-2016 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 419 438 8.8E-55 T 22-04-2016 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 85 105 5.9E-9 T 22-04-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 359 381 5.9E-9 T 22-04-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 418 440 5.9E-9 T 22-04-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 59 83 5.9E-9 T 22-04-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 Pfam PF00361 Proton-conducting membrane transporter 134 424 1.4E-91 T 22-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 PANTHER PTHR22773:SF50 1 568 9.7E-224 T 22-04-2016 TOLA_RS13485 18f68f29d0d962fe97ca55612f9b5eb8 612 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 65 122 5.5E-21 T 22-04-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal TOLA_RS14385 93ce512d837b227bd205ff8d41b4edfd 387 PANTHER PTHR16254 1 387 4.3E-204 T 22-04-2016 TOLA_RS14385 93ce512d837b227bd205ff8d41b4edfd 387 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 16 292 8.3E-73 T 22-04-2016 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 TOLA_RS14385 93ce512d837b227bd205ff8d41b4edfd 387 Pfam PF00999 Sodium/hydrogen exchanger family 15 382 9.0E-73 T 22-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TOLA_RS14385 93ce512d837b227bd205ff8d41b4edfd 387 PANTHER PTHR16254:SF17 1 387 4.3E-204 T 22-04-2016 TOLA_RS04340 325d3a434eee4c117ae74fdfb956c1a4 320 PIRSF PIRSF005427 1 320 3.2E-76 T 22-04-2016 IPR005588 MucB/RseB TOLA_RS04340 325d3a434eee4c117ae74fdfb956c1a4 320 Pfam PF17188 MucB/RseB C-terminal domain 218 317 4.7E-24 T 22-04-2016 IPR033436 MucB/RseB, C-terminal TOLA_RS04340 325d3a434eee4c117ae74fdfb956c1a4 320 PANTHER PTHR38782:SF1 1 320 4.9E-58 T 22-04-2016 TOLA_RS04340 325d3a434eee4c117ae74fdfb956c1a4 320 Gene3D G3DSA:2.50.20.10 120 179 4.1E-4 T 22-04-2016 TOLA_RS04340 325d3a434eee4c117ae74fdfb956c1a4 320 PANTHER PTHR38782 1 320 4.9E-58 T 22-04-2016 TOLA_RS04340 325d3a434eee4c117ae74fdfb956c1a4 320 Pfam PF03888 MucB/RseB N-terminal domain 23 189 3.0E-42 T 22-04-2016 IPR033434 MucB/RseB, N-terminal TOLA_RS03490 c750ff7c66f8e4ea5a582d30aeab42f7 641 Pfam PF00593 TonB dependent receptor 400 640 3.6E-25 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 TOLA_RS03490 c750ff7c66f8e4ea5a582d30aeab42f7 641 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 144 1.3E-10 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 TOLA_RS03490 c750ff7c66f8e4ea5a582d30aeab42f7 641 PANTHER PTHR32552 6 641 2.3E-31 T 22-04-2016 TOLA_RS03490 c750ff7c66f8e4ea5a582d30aeab42f7 641 Gene3D G3DSA:2.40.170.20 150 641 7.2E-70 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 TOLA_RS03490 c750ff7c66f8e4ea5a582d30aeab42f7 641 SUPERFAMILY SSF56935 27 641 1.01E-83 T 22-04-2016 TOLA_RS03490 c750ff7c66f8e4ea5a582d30aeab42f7 641 Gene3D G3DSA:2.170.130.10 46 149 1.2E-19 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 TOLA_RS03490 c750ff7c66f8e4ea5a582d30aeab42f7 641 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 624 641 - T 22-04-2016 IPR010917 TonB-dependent receptor, conserved site TOLA_RS15950 5b0fb8ed98402e0903d11cf365d26041 228 PANTHER PTHR11922:SF45 42 201 4.7E-55 T 22-04-2016 TOLA_RS15950 5b0fb8ed98402e0903d11cf365d26041 228 PANTHER PTHR11922:SF45 222 227 4.7E-55 T 22-04-2016 TOLA_RS15950 5b0fb8ed98402e0903d11cf365d26041 228 Pfam PF00117 Glutamine amidotransferase class-I 40 182 3.3E-17 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 TOLA_RS15950 5b0fb8ed98402e0903d11cf365d26041 228 SUPERFAMILY SSF52317 1 202 4.44E-46 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS15950 5b0fb8ed98402e0903d11cf365d26041 228 PANTHER PTHR11922 42 201 4.7E-55 T 22-04-2016 TOLA_RS15950 5b0fb8ed98402e0903d11cf365d26041 228 PANTHER PTHR11922 222 227 4.7E-55 T 22-04-2016 TOLA_RS15950 5b0fb8ed98402e0903d11cf365d26041 228 Gene3D G3DSA:3.40.50.880 1 225 1.2E-58 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS06490 7f2db31119086471c4407c9b0158f646 73 Gene3D G3DSA:3.30.1910.10 3 64 1.4E-16 T 22-04-2016 TOLA_RS06490 7f2db31119086471c4407c9b0158f646 73 ProDom PD055267 YTFK Y0656 CYTOPLASMIC VP2585 VV0426 ESCHERICHIA S4534 VC2473 YPO3527 COLI 3 65 2.0E-6 T 22-04-2016 IPR009491 Protein of unknown function DUF1107 TOLA_RS06490 7f2db31119086471c4407c9b0158f646 73 Pfam PF06526 Protein of unknown function (DUF1107) 3 64 2.0E-23 T 22-04-2016 IPR009491 Protein of unknown function DUF1107 TOLA_RS02140 f667f3c947ff7d6a111b5793bf02043e 444 Gene3D G3DSA:3.30.450.20 319 441 9.1E-16 T 22-04-2016 TOLA_RS02140 f667f3c947ff7d6a111b5793bf02043e 444 Pfam PF03924 CHASE domain 88 242 2.4E-23 T 22-04-2016 IPR006189 CHASE domain TOLA_RS02140 f667f3c947ff7d6a111b5793bf02043e 444 SMART SM01079 83 244 6.1E-25 T 22-04-2016 IPR006189 CHASE domain TOLA_RS02140 f667f3c947ff7d6a111b5793bf02043e 444 SUPERFAMILY SSF55785 332 443 1.34E-13 T 22-04-2016 IPR000014 PAS domain TOLA_RS02140 f667f3c947ff7d6a111b5793bf02043e 444 Pfam PF08447 PAS fold 352 437 2.7E-11 T 22-04-2016 IPR013655 PAS fold-3 GO:0005515 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 7 305 38.693 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 PANTHER PTHR11405:SF16 1 303 1.4E-144 T 22-04-2016 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 8 303 1.2E-120 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 224 233 8.9E-36 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 262 267 8.9E-36 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 284 298 8.9E-36 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 79 88 8.9E-36 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 8.9E-36 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 PRINTS PR00101 Aspartate carbamoyltransferase signature 133 150 8.9E-36 T 22-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 147 2.1E-43 T 22-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 153 301 1.9E-33 T 22-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 PANTHER PTHR11405 1 303 1.4E-144 T 22-04-2016 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 Gene3D G3DSA:3.40.50.1370 8 143 2.6E-51 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 Gene3D G3DSA:3.40.50.1370 144 290 3.3E-57 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 3.7E-24 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 3.7E-24 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 3.7E-24 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 258 267 3.7E-24 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS14370 6e0d6540b39429ce2670483945b22ed7 307 SUPERFAMILY SSF53671 4 304 1.31E-102 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS08265 ebea45e52c6eaf5a79247b84dd0f4b37 231 Pfam PF00005 ABC transporter 19 160 4.5E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS08265 ebea45e52c6eaf5a79247b84dd0f4b37 231 PANTHER PTHR24220:SF404 3 222 1.7E-118 T 22-04-2016 TOLA_RS08265 ebea45e52c6eaf5a79247b84dd0f4b37 231 PANTHER PTHR24220 3 222 1.7E-118 T 22-04-2016 TOLA_RS08265 ebea45e52c6eaf5a79247b84dd0f4b37 231 Gene3D G3DSA:3.40.50.300 1 222 6.8E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08265 ebea45e52c6eaf5a79247b84dd0f4b37 231 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 231 1.6E-100 T 22-04-2016 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE TOLA_RS08265 ebea45e52c6eaf5a79247b84dd0f4b37 231 SUPERFAMILY SSF52540 2 221 1.95E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08265 ebea45e52c6eaf5a79247b84dd0f4b37 231 SMART SM00382 26 210 9.8E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS13340 5c305e1fb78b5879c0e641e6ea911613 189 PANTHER PTHR40278:SF1 1 187 3.0E-34 T 22-04-2016 TOLA_RS13340 5c305e1fb78b5879c0e641e6ea911613 189 Pfam PF05137 Fimbrial assembly protein (PilN) 100 176 1.6E-11 T 22-04-2016 IPR007813 Fimbrial assembly PilN TOLA_RS13340 5c305e1fb78b5879c0e641e6ea911613 189 PANTHER PTHR40278 1 187 3.0E-34 T 22-04-2016 TOLA_RS01735 c9621ef703f57f84008ef8673fad2923 162 Pfam PF03734 L,D-transpeptidase catalytic domain 26 160 2.2E-18 T 22-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 TOLA_RS01735 c9621ef703f57f84008ef8673fad2923 162 Gene3D G3DSA:2.40.440.10 24 161 1.8E-18 T 22-04-2016 TOLA_RS01735 c9621ef703f57f84008ef8673fad2923 162 PANTHER PTHR36699 20 162 1.4E-44 T 22-04-2016 TOLA_RS01735 c9621ef703f57f84008ef8673fad2923 162 SUPERFAMILY SSF141523 25 160 3.53E-24 T 22-04-2016 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 Gene3D G3DSA:2.120.10.90 530 839 1.6E-142 T 22-04-2016 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 Gene3D G3DSA:3.90.199.10 34 216 2.6E-84 T 22-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 793 839 1.4E-13 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 645 688 4.3E-8 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 588 638 6.5E-12 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 538 584 1.8E-9 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 744 789 2.3E-13 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 693 737 4.6E-16 T 22-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 SUPERFAMILY SSF101904 533 850 5.75E-115 T 22-04-2016 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 840 0.0 T 22-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 PANTHER PTHR10169 450 812 0.0 T 22-04-2016 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 PANTHER PTHR10169 2 418 0.0 T 22-04-2016 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 SMART SM00434 11 499 5.7E-299 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 506 2.1E-155 T 22-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 Gene3D G3DSA:1.10.268.10 363 497 2.4E-50 T 22-04-2016 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 843 30.475 T 22-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 SUPERFAMILY SSF56719 30 521 1.29E-185 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 Gene3D G3DSA:3.30.1360.40 236 333 3.5E-38 T 22-04-2016 IPR024946 Arginine repressor C-terminal-like domain TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 PANTHER PTHR10169:SF48 450 812 0.0 T 22-04-2016 TOLA_RS07310 3db22781dad04d73a591f03a40b74885 862 PANTHER PTHR10169:SF48 2 418 0.0 T 22-04-2016 TOLA_RS08880 e2e16bba6e0ba66dd464d9578fdada21 505 PANTHER PTHR23501:SF52 3 495 3.1E-219 T 22-04-2016 TOLA_RS08880 e2e16bba6e0ba66dd464d9578fdada21 505 Gene3D G3DSA:1.20.1250.20 262 421 6.9E-13 T 22-04-2016 TOLA_RS08880 e2e16bba6e0ba66dd464d9578fdada21 505 Gene3D G3DSA:1.20.1250.20 17 195 4.0E-29 T 22-04-2016 TOLA_RS08880 e2e16bba6e0ba66dd464d9578fdada21 505 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 489 8.1E-139 T 22-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 TOLA_RS08880 e2e16bba6e0ba66dd464d9578fdada21 505 SUPERFAMILY SSF103473 251 422 1.1E-57 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS08880 e2e16bba6e0ba66dd464d9578fdada21 505 SUPERFAMILY SSF103473 468 490 1.1E-57 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS08880 e2e16bba6e0ba66dd464d9578fdada21 505 SUPERFAMILY SSF103473 14 198 1.1E-57 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS08880 e2e16bba6e0ba66dd464d9578fdada21 505 Pfam PF07690 Major Facilitator Superfamily 19 412 2.3E-46 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS08880 e2e16bba6e0ba66dd464d9578fdada21 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 6.9E-8 T 22-04-2016 TOLA_RS08880 e2e16bba6e0ba66dd464d9578fdada21 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 6.9E-8 T 22-04-2016 TOLA_RS08880 e2e16bba6e0ba66dd464d9578fdada21 505 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 6.9E-8 T 22-04-2016 TOLA_RS08880 e2e16bba6e0ba66dd464d9578fdada21 505 PANTHER PTHR23501 3 495 3.1E-219 T 22-04-2016 TOLA_RS12855 5d6b0c19b5f460fb7d4dabdb10c7fc35 361 Gene3D G3DSA:3.40.140.10 1 122 2.8E-32 T 22-04-2016 TOLA_RS12855 5d6b0c19b5f460fb7d4dabdb10c7fc35 361 SUPERFAMILY SSF53927 1 139 3.9E-45 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 TOLA_RS12855 5d6b0c19b5f460fb7d4dabdb10c7fc35 361 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 44 82 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TOLA_RS12855 5d6b0c19b5f460fb7d4dabdb10c7fc35 361 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 1 93 1.0E-18 T 22-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 TOLA_RS12855 5d6b0c19b5f460fb7d4dabdb10c7fc35 361 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 1 356 9.0E-132 T 22-04-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525|UniPathway: UPA00275|UniPathway: UPA00275 TOLA_RS12855 5d6b0c19b5f460fb7d4dabdb10c7fc35 361 PANTHER PTHR11079 1 226 1.9E-68 T 22-04-2016 TOLA_RS12855 5d6b0c19b5f460fb7d4dabdb10c7fc35 361 PANTHER PTHR11079:SF10 1 226 1.9E-68 T 22-04-2016 TOLA_RS12855 5d6b0c19b5f460fb7d4dabdb10c7fc35 361 Gene3D G3DSA:3.40.430.10 123 358 1.3E-67 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain TOLA_RS12855 5d6b0c19b5f460fb7d4dabdb10c7fc35 361 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 140 359 3.5E-64 T 22-04-2016 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 TOLA_RS12855 5d6b0c19b5f460fb7d4dabdb10c7fc35 361 Pfam PF01872 RibD C-terminal domain 141 354 5.1E-51 T 22-04-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TOLA_RS12855 5d6b0c19b5f460fb7d4dabdb10c7fc35 361 SUPERFAMILY SSF53597 139 357 9.29E-60 T 22-04-2016 IPR024072 Dihydrofolate reductase-like domain TOLA_RS12855 5d6b0c19b5f460fb7d4dabdb10c7fc35 361 PIRSF PIRSF006769 1 361 8.8E-128 T 22-04-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525|UniPathway: UPA00275|UniPathway: UPA00275 TOLA_RS06035 f8bb9f8903f585b7685d19e72fa9285a 348 PANTHER PTHR30547 1 335 6.8E-133 T 22-04-2016 TOLA_RS06035 f8bb9f8903f585b7685d19e72fa9285a 348 PANTHER PTHR30547:SF5 1 335 6.8E-133 T 22-04-2016 TOLA_RS06035 f8bb9f8903f585b7685d19e72fa9285a 348 Pfam PF06250 Protein of unknown function (DUF1016) 15 330 2.3E-120 T 22-04-2016 IPR009362 Protein of unknown function DUF1016 TOLA_RS04865 d1b4ed86d7e5ce0e98f6e6356850545b 232 Gene3D G3DSA:3.40.50.620 5 217 6.7E-88 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS04865 d1b4ed86d7e5ce0e98f6e6356850545b 232 SUPERFAMILY SSF52402 5 216 2.65E-70 T 22-04-2016 TOLA_RS04865 d1b4ed86d7e5ce0e98f6e6356850545b 232 PIRSF PIRSF006293 4 228 1.5E-83 T 22-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 TOLA_RS04865 d1b4ed86d7e5ce0e98f6e6356850545b 232 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 6 222 51.027 T 22-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 TOLA_RS04865 d1b4ed86d7e5ce0e98f6e6356850545b 232 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 8 209 1.9E-86 T 22-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 TOLA_RS04865 d1b4ed86d7e5ce0e98f6e6356850545b 232 Pfam PF06508 Queuosine biosynthesis protein QueC 7 216 1.2E-85 T 22-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 TOLA_RS04865 d1b4ed86d7e5ce0e98f6e6356850545b 232 PANTHER PTHR11587 3 216 7.2E-102 T 22-04-2016 TOLA_RS04865 d1b4ed86d7e5ce0e98f6e6356850545b 232 PANTHER PTHR11587:SF3 3 216 7.2E-102 T 22-04-2016 TOLA_RS07040 86837cddeb724c46c259faf95e9b4205 384 Pfam PF00155 Aminotransferase class I and II 30 370 2.3E-30 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TOLA_RS07040 86837cddeb724c46c259faf95e9b4205 384 Gene3D G3DSA:3.90.1150.10 246 376 2.6E-30 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS07040 86837cddeb724c46c259faf95e9b4205 384 Gene3D G3DSA:3.40.640.10 39 245 8.5E-49 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS07040 86837cddeb724c46c259faf95e9b4205 384 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 4 375 1.0E-129 T 22-04-2016 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 TOLA_RS07040 86837cddeb724c46c259faf95e9b4205 384 SUPERFAMILY SSF53383 1 375 5.15E-90 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS07040 86837cddeb724c46c259faf95e9b4205 384 PANTHER PTHR11751:SF422 3 382 2.4E-119 T 22-04-2016 TOLA_RS07040 86837cddeb724c46c259faf95e9b4205 384 PANTHER PTHR11751 3 382 2.4E-119 T 22-04-2016 TOLA_RS03750 6eab8c847e38a25cbe5c8fcfd2f1bf3a 181 Pfam PF09374 Predicted Peptidoglycan domain 101 167 1.1E-10 T 22-04-2016 IPR018537 Peptidoglycan binding domain TOLA_RS03750 6eab8c847e38a25cbe5c8fcfd2f1bf3a 181 Gene3D G3DSA:1.20.141.10 2 170 5.4E-48 T 22-04-2016 TOLA_RS03750 6eab8c847e38a25cbe5c8fcfd2f1bf3a 181 SUPERFAMILY SSF53955 2 170 2.76E-41 T 22-04-2016 IPR023346 Lysozyme-like domain TOLA_RS03750 6eab8c847e38a25cbe5c8fcfd2f1bf3a 181 Pfam PF05838 Glycosyl hydrolase 108 7 99 2.3E-22 T 22-04-2016 IPR008565 Protein of unknown function DUF847 TOLA_RS09970 e77ab06bc7338e82bbb4d1ef0602a5c2 230 Gene3D G3DSA:1.20.120.530 73 209 4.5E-26 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal TOLA_RS09970 e77ab06bc7338e82bbb4d1ef0602a5c2 230 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 4.1E-13 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS09970 e77ab06bc7338e82bbb4d1ef0602a5c2 230 SMART SM00345 12 70 3.9E-9 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS09970 e77ab06bc7338e82bbb4d1ef0602a5c2 230 SUPERFAMILY SSF46785 7 74 1.52E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09970 e77ab06bc7338e82bbb4d1ef0602a5c2 230 SUPERFAMILY SSF48008 77 208 1.52E-21 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal TOLA_RS09970 e77ab06bc7338e82bbb4d1ef0602a5c2 230 PANTHER PTHR11751 10 96 8.8E-19 T 22-04-2016 TOLA_RS09970 e77ab06bc7338e82bbb4d1ef0602a5c2 230 Pfam PF07729 FCD domain 80 202 7.1E-18 T 22-04-2016 IPR011711 GntR, C-terminal TOLA_RS09970 e77ab06bc7338e82bbb4d1ef0602a5c2 230 Gene3D G3DSA:1.10.10.10 4 71 1.2E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09970 e77ab06bc7338e82bbb4d1ef0602a5c2 230 SMART SM00895 80 203 9.1E-17 T 22-04-2016 IPR011711 GntR, C-terminal TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 PANTHER PTHR10357:SF11 436 682 5.3E-119 T 22-04-2016 TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 PANTHER PTHR10357:SF11 225 322 5.3E-119 T 22-04-2016 TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 PANTHER PTHR10357:SF11 157 209 5.3E-119 T 22-04-2016 TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 PANTHER PTHR10357:SF11 351 412 5.3E-119 T 22-04-2016 TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 SUPERFAMILY SSF51445 142 656 5.17E-75 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 PANTHER PTHR10357 436 682 5.3E-119 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 PANTHER PTHR10357 225 322 5.3E-119 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 PANTHER PTHR10357 157 209 5.3E-119 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 PANTHER PTHR10357 351 412 5.3E-119 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 Pfam PF00128 Alpha amylase, catalytic domain 228 606 1.8E-42 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 Gene3D G3DSA:3.20.20.80 185 654 5.7E-90 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 PIRSF PIRSF036917 1 686 0.0 T 22-04-2016 IPR014635 Alpha-amylase, MalS type GO:0004556|GO:0005509|GO:0030980|GO:0042597|GO:0051692 KEGG: 00500+3.2.1.1 TOLA_RS03345 d1bf5ec3894286a51f09a75f3d1736fa 688 SMART SM00642 195 647 3.7E-76 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS12750 6ef6456a268ad7fac6812d724e242943 296 PANTHER PTHR12001:SF23 10 274 4.0E-103 T 22-04-2016 TOLA_RS12750 6ef6456a268ad7fac6812d724e242943 296 SUPERFAMILY SSF48576 3 289 2.67E-86 T 22-04-2016 IPR008949 Isoprenoid synthase domain TOLA_RS12750 6ef6456a268ad7fac6812d724e242943 296 PANTHER PTHR12001 10 274 4.0E-103 T 22-04-2016 IPR017446 Polyprenyl synthetase-related TOLA_RS12750 6ef6456a268ad7fac6812d724e242943 296 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 97 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 TOLA_RS12750 6ef6456a268ad7fac6812d724e242943 296 Gene3D G3DSA:1.10.600.10 5 294 2.4E-88 T 22-04-2016 IPR008949 Isoprenoid synthase domain TOLA_RS12750 6ef6456a268ad7fac6812d724e242943 296 Pfam PF00348 Polyprenyl synthetase 31 265 1.3E-55 T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 TOLA_RS12750 6ef6456a268ad7fac6812d724e242943 296 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 22-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 TOLA_RS16100 5792cd4228c404d156de224a42a5b4bd 75 ProSitePatterns PS00605 ATP synthase c subunit signature. 35 56 - T 22-04-2016 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site TOLA_RS16100 5792cd4228c404d156de224a42a5b4bd 75 PRINTS PR00124 ATP synthase C subunit signature 28 43 6.41E-8 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 TOLA_RS16100 5792cd4228c404d156de224a42a5b4bd 75 PRINTS PR00124 ATP synthase C subunit signature 45 70 6.41E-8 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 TOLA_RS16100 5792cd4228c404d156de224a42a5b4bd 75 PRINTS PR00124 ATP synthase C subunit signature 7 26 6.41E-8 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 TOLA_RS16100 5792cd4228c404d156de224a42a5b4bd 75 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 15 72 2.9E-30 T 22-04-2016 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TOLA_RS16100 5792cd4228c404d156de224a42a5b4bd 75 Hamap MF_01396 ATP synthase subunit c [atpH]. 4 72 14.632 T 22-04-2016 TOLA_RS16100 5792cd4228c404d156de224a42a5b4bd 75 SUPERFAMILY SSF81333 3 72 5.23E-17 T 22-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TOLA_RS16100 5792cd4228c404d156de224a42a5b4bd 75 Pfam PF00137 ATP synthase subunit C 6 63 5.1E-11 T 22-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TOLA_RS16100 5792cd4228c404d156de224a42a5b4bd 75 Gene3D G3DSA:1.20.20.10 1 72 1.2E-29 T 22-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 TOLA_RS16100 5792cd4228c404d156de224a42a5b4bd 75 PANTHER PTHR10031 5 73 8.2E-22 T 22-04-2016 TOLA_RS16250 66ef1bd6e16f109f7bee775bccde8e27 45 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 43 5.9E-24 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS16250 66ef1bd6e16f109f7bee775bccde8e27 45 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.667 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS16250 66ef1bd6e16f109f7bee775bccde8e27 45 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 22-04-2016 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS16250 66ef1bd6e16f109f7bee775bccde8e27 45 PANTHER PTHR14503 1 44 2.1E-20 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS16250 66ef1bd6e16f109f7bee775bccde8e27 45 Pfam PF00468 Ribosomal protein L34 1 43 2.1E-23 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS16250 66ef1bd6e16f109f7bee775bccde8e27 45 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 24 4.0E-6 T 22-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15515 1599ecf7e4a839c08f7591bf89f54c0f 202 ProSitePatterns PS00194 Thioredoxin family active site. 42 60 - T 22-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 TOLA_RS15515 1599ecf7e4a839c08f7591bf89f54c0f 202 PANTHER PTHR35891:SF2 1 202 7.7E-75 T 22-04-2016 TOLA_RS15515 1599ecf7e4a839c08f7591bf89f54c0f 202 PANTHER PTHR35891 1 202 7.7E-75 T 22-04-2016 TOLA_RS15515 1599ecf7e4a839c08f7591bf89f54c0f 202 Pfam PF01323 DSBA-like thioredoxin domain 42 178 3.0E-20 T 22-04-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 TOLA_RS15515 1599ecf7e4a839c08f7591bf89f54c0f 202 PIRSF PIRSF001488 1 201 1.2E-60 T 22-04-2016 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL TOLA_RS15515 1599ecf7e4a839c08f7591bf89f54c0f 202 SUPERFAMILY SSF52833 21 199 6.67E-42 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS15515 1599ecf7e4a839c08f7591bf89f54c0f 202 Gene3D G3DSA:3.40.30.10 120 199 7.0E-21 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS15515 1599ecf7e4a839c08f7591bf89f54c0f 202 Gene3D G3DSA:3.40.30.10 1 118 9.7E-37 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 672 683 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 Gene3D G3DSA:3.30.43.10 2 107 4.9E-22 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 SUPERFAMILY SSF55103 258 542 2.94E-50 T 22-04-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 Gene3D G3DSA:1.10.1060.10 517 618 6.9E-14 T 22-04-2016 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 Gene3D G3DSA:1.10.1060.10 653 705 6.9E-14 T 22-04-2016 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 PANTHER PTHR11748:SF35 249 586 1.4E-163 T 22-04-2016 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 PANTHER PTHR11748:SF35 17 198 1.4E-163 T 22-04-2016 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 PANTHER PTHR11748 249 586 1.4E-163 T 22-04-2016 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 PANTHER PTHR11748 17 198 1.4E-163 T 22-04-2016 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 SUPERFAMILY SSF56176 18 282 3.19E-50 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 Gene3D G3DSA:3.30.465.10 110 282 3.7E-39 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 Pfam PF02913 FAD linked oxidases, C-terminal domain 282 538 2.4E-59 T 22-04-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 Pfam PF13183 4Fe-4S dicluster domain 574 686 1.2E-10 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 Pfam PF01565 FAD binding domain 52 191 9.1E-33 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 SUPERFAMILY SSF46548 654 689 5.49E-7 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 TOLA_RS03080 9e7beec971300908a78c8869a6f79e8b 1016 SUPERFAMILY SSF46548 559 621 5.49E-7 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 PANTHER PTHR10457 2 384 2.6E-152 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 Pfam PF08544 GHMP kinases C terminal 281 363 3.5E-13 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 SUPERFAMILY SSF54211 3 203 5.84E-66 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 SUPERFAMILY SSF55060 204 383 7.2E-52 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 PRINTS PR00959 Mevalonate kinase family signature 162 181 2.3E-45 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 PRINTS PR00959 Mevalonate kinase family signature 25 49 2.3E-45 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 PRINTS PR00959 Mevalonate kinase family signature 119 141 2.3E-45 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 PRINTS PR00959 Mevalonate kinase family signature 330 347 2.3E-45 T 22-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 Gene3D G3DSA:3.30.230.10 5 207 1.2E-81 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 PRINTS PR00473 Galactokinase signature 92 103 4.6E-30 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 PRINTS PR00473 Galactokinase signature 112 130 4.6E-30 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 PRINTS PR00473 Galactokinase signature 27 45 4.6E-30 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 PRINTS PR00473 Galactokinase signature 265 279 4.6E-30 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 Gene3D G3DSA:3.30.70.890 208 382 1.6E-62 T 22-04-2016 IPR013750 GHMP kinase, C-terminal domain TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 Hamap MF_00246 Galactokinase [galK]. 25 383 42.963 T 22-04-2016 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 PANTHER PTHR10457:SF6 2 384 2.6E-152 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 Pfam PF00288 GHMP kinases N terminal domain 115 181 2.3E-13 T 22-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 ProSitePatterns PS00106 Galactokinase signature. 27 38 - T 22-04-2016 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 PIRSF PIRSF000530 1 384 2.2E-125 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 Pfam PF10509 Galactokinase galactose-binding signature 11 57 7.6E-24 T 22-04-2016 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 TIGRFAM TIGR00131 gal_kin: galactokinase 5 382 3.3E-142 T 22-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 TOLA_RS13400 fb6cc07af2d73ee876f6a7c56decb460 384 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 22-04-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TOLA_RS01265 7c26d30ceb3837617875990c9fb81166 146 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 146 31.732 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 TOLA_RS01265 7c26d30ceb3837617875990c9fb81166 146 Gene3D G3DSA:3.50.80.10 1 145 3.5E-52 T 22-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain TOLA_RS01265 7c26d30ceb3837617875990c9fb81166 146 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 3 144 6.9E-49 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 TOLA_RS01265 7c26d30ceb3837617875990c9fb81166 146 SUPERFAMILY SSF69500 1 145 1.96E-51 T 22-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain TOLA_RS01265 7c26d30ceb3837617875990c9fb81166 146 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 146 4.2E-64 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 TOLA_RS01265 7c26d30ceb3837617875990c9fb81166 146 PANTHER PTHR10472 2 145 8.2E-66 T 22-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 TOLA_RS11640 084a97e5dc6c52eccfa6843c4c11d4cc 203 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 37 142 6.6E-15 T 22-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 TOLA_RS11640 084a97e5dc6c52eccfa6843c4c11d4cc 203 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 90 131 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TOLA_RS11640 084a97e5dc6c52eccfa6843c4c11d4cc 203 Gene3D G3DSA:3.40.140.10 30 191 8.6E-40 T 22-04-2016 TOLA_RS11640 084a97e5dc6c52eccfa6843c4c11d4cc 203 PANTHER PTHR11079:SF77 23 178 9.7E-34 T 22-04-2016 TOLA_RS11640 084a97e5dc6c52eccfa6843c4c11d4cc 203 PANTHER PTHR11079 23 178 9.7E-34 T 22-04-2016 TOLA_RS11640 084a97e5dc6c52eccfa6843c4c11d4cc 203 SUPERFAMILY SSF53927 18 195 3.19E-38 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 TOLA_RS08025 fbef0ee5c6d451665b6dbfd0168ac407 315 SUPERFAMILY SSF144083 250 313 1.83E-20 T 22-04-2016 TOLA_RS08025 fbef0ee5c6d451665b6dbfd0168ac407 315 PANTHER PTHR21535:SF37 20 315 1.9E-94 T 22-04-2016 TOLA_RS08025 fbef0ee5c6d451665b6dbfd0168ac407 315 PANTHER PTHR21535 20 315 1.9E-94 T 22-04-2016 TOLA_RS08025 fbef0ee5c6d451665b6dbfd0168ac407 315 Gene3D G3DSA:1.20.58.340 239 315 6.8E-27 T 22-04-2016 TOLA_RS08025 fbef0ee5c6d451665b6dbfd0168ac407 315 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 20 315 7.1E-67 T 22-04-2016 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 TOLA_RS08025 fbef0ee5c6d451665b6dbfd0168ac407 315 Pfam PF01544 CorA-like Mg2+ transporter protein 27 311 7.4E-57 T 22-04-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 TOLA_RS08025 fbef0ee5c6d451665b6dbfd0168ac407 315 SUPERFAMILY SSF143865 1 254 1.96E-30 T 22-04-2016 TOLA_RS13295 684a67f9a7aad1845b65c36badc07d5f 471 SUPERFAMILY SSF52540 9 159 1.49E-8 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13295 684a67f9a7aad1845b65c36badc07d5f 471 Pfam PF13401 AAA domain 7 107 2.8E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS13295 684a67f9a7aad1845b65c36badc07d5f 471 Pfam PF05036 Sporulation related domain 389 456 2.8E-6 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 TOLA_RS06275 925bd5c440445ed5cbceff5087671b64 342 Gene3D G3DSA:3.40.190.10 129 226 6.0E-14 T 22-04-2016 TOLA_RS06275 925bd5c440445ed5cbceff5087671b64 342 PANTHER PTHR30085:SF5 13 311 3.3E-166 T 22-04-2016 TOLA_RS06275 925bd5c440445ed5cbceff5087671b64 342 SUPERFAMILY SSF53850 29 258 3.72E-43 T 22-04-2016 TOLA_RS06275 925bd5c440445ed5cbceff5087671b64 342 Gene3D G3DSA:3.40.190.10 227 241 2.0E-14 T 22-04-2016 TOLA_RS06275 925bd5c440445ed5cbceff5087671b64 342 Gene3D G3DSA:3.40.190.10 35 128 2.0E-14 T 22-04-2016 TOLA_RS06275 925bd5c440445ed5cbceff5087671b64 342 SMART SM00062 38 267 2.4E-45 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS06275 925bd5c440445ed5cbceff5087671b64 342 PANTHER PTHR30085 13 311 3.3E-166 T 22-04-2016 TOLA_RS06275 925bd5c440445ed5cbceff5087671b64 342 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 256 1.7E-26 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS15725 d439458a9ba1dfdb0fa01869816e903a 290 Pfam PF01261 Xylose isomerase-like TIM barrel 30 238 6.7E-33 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS15725 d439458a9ba1dfdb0fa01869816e903a 290 Gene3D G3DSA:3.20.20.150 11 275 3.1E-47 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS15725 d439458a9ba1dfdb0fa01869816e903a 290 PANTHER PTHR12110 3 287 1.1E-94 T 22-04-2016 TOLA_RS15725 d439458a9ba1dfdb0fa01869816e903a 290 PANTHER PTHR12110:SF17 3 287 1.1E-94 T 22-04-2016 TOLA_RS15725 d439458a9ba1dfdb0fa01869816e903a 290 TIGRFAM TIGR00542 hxl6Piso_put: putative hexulose-6-phosphate isomerase 8 287 1.2E-103 T 22-04-2016 IPR004560 L-ribulose-5-phosphate 3-epimerase GO:0005975|GO:0016861 KEGG: 00053+5.1.3.22|MetaCyc: PWY-6961|UniPathway: UPA00263 TOLA_RS15725 d439458a9ba1dfdb0fa01869816e903a 290 SUPERFAMILY SSF51658 2 281 1.7E-53 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS14280 ef5f1f2930082e8b52daac85def3a7eb 127 PANTHER PTHR33910 1 126 2.5E-26 T 22-04-2016 TOLA_RS14280 ef5f1f2930082e8b52daac85def3a7eb 127 PRINTS PR01650 Bacterial translocase SecE signature 44 65 6.8E-23 T 22-04-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 TOLA_RS14280 ef5f1f2930082e8b52daac85def3a7eb 127 PRINTS PR01650 Bacterial translocase SecE signature 65 85 6.8E-23 T 22-04-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 TOLA_RS14280 ef5f1f2930082e8b52daac85def3a7eb 127 PRINTS PR01650 Bacterial translocase SecE signature 89 109 6.8E-23 T 22-04-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 TOLA_RS14280 ef5f1f2930082e8b52daac85def3a7eb 127 PRINTS PR01650 Bacterial translocase SecE signature 109 125 6.8E-23 T 22-04-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 TOLA_RS14280 ef5f1f2930082e8b52daac85def3a7eb 127 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 70 122 3.5E-19 T 22-04-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 TOLA_RS14280 ef5f1f2930082e8b52daac85def3a7eb 127 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 70 123 3.7E-18 T 22-04-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 TOLA_RS14280 ef5f1f2930082e8b52daac85def3a7eb 127 PANTHER PTHR33910:SF1 1 126 2.5E-26 T 22-04-2016 TOLA_RS14280 ef5f1f2930082e8b52daac85def3a7eb 127 Gene3D G3DSA:1.20.5.1030 65 123 4.9E-23 T 22-04-2016 TOLA_RS14280 ef5f1f2930082e8b52daac85def3a7eb 127 Hamap MF_00422 Protein translocase subunit SecE [secE]. 66 121 12.926 T 22-04-2016 IPR022943 Preprotein translocase subunit SecE TOLA_RS00830 61d782f58a229a9a4ffb57002c2ded44 180 PANTHER PTHR13061 12 178 2.8E-67 T 22-04-2016 TOLA_RS00830 61d782f58a229a9a4ffb57002c2ded44 180 Gene3D G3DSA:2.160.10.10 4 174 1.1E-40 T 22-04-2016 TOLA_RS00830 61d782f58a229a9a4ffb57002c2ded44 180 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 96 129 2.6E-7 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS00830 61d782f58a229a9a4ffb57002c2ded44 180 SUPERFAMILY SSF51161 4 174 1.19E-41 T 22-04-2016 IPR011004 Trimeric LpxA-like TOLA_RS03930 1ac2c29ad3763008d4602f4288c29ce2 270 Gene3D G3DSA:3.40.50.720 2 82 3.8E-8 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS03930 1ac2c29ad3763008d4602f4288c29ce2 270 Gene3D G3DSA:3.40.50.720 88 214 3.5E-14 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS03930 1ac2c29ad3763008d4602f4288c29ce2 270 PANTHER PTHR10366:SF289 5 266 3.8E-28 T 22-04-2016 TOLA_RS03930 1ac2c29ad3763008d4602f4288c29ce2 270 SUPERFAMILY SSF51735 11 264 4.98E-25 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS03930 1ac2c29ad3763008d4602f4288c29ce2 270 PANTHER PTHR10366 5 266 3.8E-28 T 22-04-2016 TOLA_RS03930 1ac2c29ad3763008d4602f4288c29ce2 270 Pfam PF13460 NAD(P)H-binding 12 176 1.6E-7 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 SUPERFAMILY SSF51412 217 477 5.1E-122 T 22-04-2016 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 SUPERFAMILY SSF51412 1 90 5.1E-122 T 22-04-2016 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 295 307 - T 22-04-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Reactome: REACT_1698 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 8 454 5.3E-192 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 PIRSF PIRSF000130 1 487 8.7E-194 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 PANTHER PTHR11911 300 486 9.5E-240 T 22-04-2016 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 PANTHER PTHR11911 1 282 9.5E-240 T 22-04-2016 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 8 473 1.9E-156 T 22-04-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 Pfam PF00571 CBS domain 149 203 7.7E-6 T 22-04-2016 IPR000644 CBS domain TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 Pfam PF00571 CBS domain 95 140 3.2E-9 T 22-04-2016 IPR000644 CBS domain TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 SMART SM01240 7 473 0.0 T 22-04-2016 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 PANTHER PTHR11911:SF6 300 486 9.5E-240 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 PANTHER PTHR11911:SF6 1 282 9.5E-240 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 Gene3D G3DSA:3.20.20.70 2 485 2.3E-191 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 8 486 81.936 T 22-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 SUPERFAMILY SSF54631 94 203 3.79E-27 T 22-04-2016 TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 SMART SM00116 96 144 1.0E-8 T 22-04-2016 IPR000644 CBS domain TOLA_RS11030 99d412882e38126d2de1950bf328bb3e 487 SMART SM00116 158 206 1.6E-7 T 22-04-2016 IPR000644 CBS domain TOLA_RS01370 abf2c3b977ca8a761c758c6e01145fb4 273 Gene3D G3DSA:3.60.110.10 1 266 9.7E-84 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS01370 abf2c3b977ca8a761c758c6e01145fb4 273 SUPERFAMILY SSF56317 2 261 2.35E-77 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS01370 abf2c3b977ca8a761c758c6e01145fb4 273 PANTHER PTHR23088 1 266 3.6E-101 T 22-04-2016 TOLA_RS01370 abf2c3b977ca8a761c758c6e01145fb4 273 PANTHER PTHR23088:SF27 1 266 3.6E-101 T 22-04-2016 TOLA_RS01370 abf2c3b977ca8a761c758c6e01145fb4 273 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 150 170 - T 22-04-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site TOLA_RS01370 abf2c3b977ca8a761c758c6e01145fb4 273 Pfam PF00795 Carbon-nitrogen hydrolase 16 257 3.0E-52 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS08960 852eb966bcd900cd2a037f0bed1f016f 109 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 2 107 4.4E-36 T 22-04-2016 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 TOLA_RS08960 852eb966bcd900cd2a037f0bed1f016f 109 Gene3D G3DSA:2.102.10.10 1 108 4.6E-40 T 22-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TOLA_RS08960 852eb966bcd900cd2a037f0bed1f016f 109 Pfam PF13806 Rieske-like [2Fe-2S] domain 2 106 2.6E-37 T 22-04-2016 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 TOLA_RS08960 852eb966bcd900cd2a037f0bed1f016f 109 PANTHER PTHR40562 3 102 9.7E-28 T 22-04-2016 TOLA_RS08960 852eb966bcd900cd2a037f0bed1f016f 109 SUPERFAMILY SSF50022 1 108 9.95E-35 T 22-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TOLA_RS02880 49f422bacb992ef39541caabcbc788b4 240 PIRSF PIRSF006232 1 238 2.0E-55 T 22-04-2016 IPR012093 Pirin TOLA_RS02880 49f422bacb992ef39541caabcbc788b4 240 Gene3D G3DSA:2.60.120.10 4 233 4.9E-77 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS02880 49f422bacb992ef39541caabcbc788b4 240 SUPERFAMILY SSF51182 1 233 1.1E-77 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS02880 49f422bacb992ef39541caabcbc788b4 240 PANTHER PTHR13903:SF7 1 240 1.3E-114 T 22-04-2016 TOLA_RS02880 49f422bacb992ef39541caabcbc788b4 240 Pfam PF02678 Pirin 11 119 1.3E-35 T 22-04-2016 IPR003829 Pirin, N-terminal domain TOLA_RS02880 49f422bacb992ef39541caabcbc788b4 240 PANTHER PTHR13903 1 240 1.3E-114 T 22-04-2016 IPR012093 Pirin TOLA_RS09590 e5554590a953be3cc3a074d8cdf04214 321 PIRSF PIRSF004692 1 321 3.7E-121 T 22-04-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 TOLA_RS09590 e5554590a953be3cc3a074d8cdf04214 321 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 43 311 3.1E-113 T 22-04-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 TOLA_RS09590 e5554590a953be3cc3a074d8cdf04214 321 SUPERFAMILY SSF53697 3 255 5.34E-58 T 22-04-2016 TOLA_RS09590 e5554590a953be3cc3a074d8cdf04214 321 Pfam PF00571 CBS domain 199 256 2.2E-5 T 22-04-2016 IPR000644 CBS domain TOLA_RS09590 e5554590a953be3cc3a074d8cdf04214 321 Pfam PF00571 CBS domain 269 315 7.1E-4 T 22-04-2016 IPR000644 CBS domain TOLA_RS09590 e5554590a953be3cc3a074d8cdf04214 321 Gene3D G3DSA:3.10.580.10 190 316 2.0E-29 T 22-04-2016 TOLA_RS09590 e5554590a953be3cc3a074d8cdf04214 321 PANTHER PTHR11911:SF98 35 318 2.4E-50 T 22-04-2016 TOLA_RS09590 e5554590a953be3cc3a074d8cdf04214 321 PANTHER PTHR11911 35 318 2.4E-50 T 22-04-2016 TOLA_RS09590 e5554590a953be3cc3a074d8cdf04214 321 SUPERFAMILY SSF54631 262 318 1.34E-7 T 22-04-2016 TOLA_RS09590 e5554590a953be3cc3a074d8cdf04214 321 Pfam PF01380 SIS domain 39 169 1.0E-30 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 TOLA_RS09590 e5554590a953be3cc3a074d8cdf04214 321 Gene3D G3DSA:3.40.50.10490 8 189 7.7E-47 T 22-04-2016 TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 PANTHER PTHR10357:SF142 449 548 7.2E-230 T 22-04-2016 TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 PANTHER PTHR10357:SF142 5 384 7.2E-230 T 22-04-2016 TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 PANTHER PTHR10357:SF142 405 417 7.2E-230 T 22-04-2016 TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 Gene3D G3DSA:3.20.20.80 9 110 8.4E-122 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 Gene3D G3DSA:3.20.20.80 182 472 8.4E-122 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 SUPERFAMILY SSF51011 473 548 2.66E-17 T 22-04-2016 TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 Pfam PF16657 Maltogenic Amylase, C-terminal domain 473 527 1.1E-7 T 22-04-2016 IPR032091 Maltogenic Amylase, C-terminal TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 SUPERFAMILY SSF51445 10 470 6.81E-153 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 Gene3D G3DSA:2.60.40.1180 475 548 6.4E-21 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 Pfam PF00128 Alpha amylase, catalytic domain 34 370 9.9E-118 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 Gene3D G3DSA:3.90.400.10 111 181 3.8E-29 T 22-04-2016 TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 SMART SM00642 19 412 1.9E-151 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 PANTHER PTHR10357 449 548 7.2E-230 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 PANTHER PTHR10357 5 384 7.2E-230 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS06300 32fcb22de598f78e08ed85de3142ab2a 555 PANTHER PTHR10357 405 417 7.2E-230 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS15365 b18325ddf86470576008587d49a3c560 447 PANTHER PTHR37839:SF1 1 447 4.6E-208 T 22-04-2016 TOLA_RS15365 b18325ddf86470576008587d49a3c560 447 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 1 257 1.5E-107 T 22-04-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 TOLA_RS15365 b18325ddf86470576008587d49a3c560 447 Pfam PF11973 NQRA C-terminal domain 262 310 1.8E-19 T 22-04-2016 IPR022615 Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain GO:0016655|GO:0055114 TOLA_RS15365 b18325ddf86470576008587d49a3c560 447 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 1 447 45.329 T 22-04-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 TOLA_RS15365 b18325ddf86470576008587d49a3c560 447 PANTHER PTHR37839 1 447 4.6E-208 T 22-04-2016 TOLA_RS15365 b18325ddf86470576008587d49a3c560 447 SUPERFAMILY SSF51230 33 82 9.55E-5 T 22-04-2016 IPR011053 Single hybrid motif TOLA_RS15365 b18325ddf86470576008587d49a3c560 447 TIGRFAM TIGR01936 nqrA: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit 2 446 3.1E-181 T 22-04-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 TOLA_RS15365 b18325ddf86470576008587d49a3c560 447 Gene3D G3DSA:2.40.50.100 42 80 1.9E-4 T 22-04-2016 TOLA_RS08040 3a8dfbf73b7a6564b9690262f63c0576 257 SMART SM00382 30 229 2.2E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS08040 3a8dfbf73b7a6564b9690262f63c0576 257 Gene3D G3DSA:3.40.50.300 6 252 4.1E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08040 3a8dfbf73b7a6564b9690262f63c0576 257 SUPERFAMILY SSF52540 6 251 6.53E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08040 3a8dfbf73b7a6564b9690262f63c0576 257 PIRSF PIRSF039085 2 257 8.1E-121 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TOLA_RS08040 3a8dfbf73b7a6564b9690262f63c0576 257 PANTHER PTHR24220:SF347 7 257 9.5E-175 T 22-04-2016 TOLA_RS08040 3a8dfbf73b7a6564b9690262f63c0576 257 PANTHER PTHR24220 7 257 9.5E-175 T 22-04-2016 TOLA_RS08040 3a8dfbf73b7a6564b9690262f63c0576 257 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS08040 3a8dfbf73b7a6564b9690262f63c0576 257 Pfam PF00005 ABC transporter 22 181 3.3E-34 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS04895 8845b0f3160d72f3b804df563193368d 745 Pfam PF05548 Gametolysin peptidase M11 259 419 7.7E-10 T 22-04-2016 IPR008752 Peptidase M11, gametolysin TOLA_RS04895 8845b0f3160d72f3b804df563193368d 745 SUPERFAMILY SSF55486 289 359 9.87E-8 T 22-04-2016 TOLA_RS04895 8845b0f3160d72f3b804df563193368d 745 Gene3D G3DSA:3.40.390.10 260 354 3.0E-4 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 TOLA_RS04895 8845b0f3160d72f3b804df563193368d 745 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 546 619 4.2E-7 T 22-04-2016 IPR018905 Alpha-galactosidase, NEW3 domain TOLA_RS04895 8845b0f3160d72f3b804df563193368d 745 Gene3D G3DSA:2.60.40.10 545 635 1.6E-5 T 22-04-2016 IPR013783 Immunoglobulin-like fold TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 SMART SM00963 135 215 4.1E-22 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 SUPERFAMILY SSF52540 228 431 6.36E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 PANTHER PTHR11564:SF16 125 433 1.9E-146 T 22-04-2016 TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 SMART SM00382 229 420 9.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 Gene3D G3DSA:3.40.50.300 227 430 2.5E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 Pfam PF02881 SRP54-type protein, helical bundle domain 149 211 2.6E-11 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 Gene3D G3DSA:1.20.120.140 137 219 1.4E-29 T 22-04-2016 TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 PANTHER PTHR11564 125 433 1.9E-146 T 22-04-2016 TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 SUPERFAMILY SSF47364 130 208 6.8E-21 T 22-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 SMART SM00962 230 431 8.0E-121 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 158 430 5.5E-112 T 22-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 Pfam PF00448 SRP54-type protein, GTPase domain 231 430 5.3E-77 T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 404 417 - T 22-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 TOLA_RS15470 6f82e851439860dc20f210531eb63199 435 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 158 431 63.68 T 22-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TOLA_RS09380 6d247e14f6a8371d5f40595806f7944a 603 Gene3D G3DSA:3.20.20.70 1 282 1.5E-120 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS09380 6d247e14f6a8371d5f40595806f7944a 603 SUPERFAMILY SSF89000 297 447 1.26E-50 T 22-04-2016 TOLA_RS09380 6d247e14f6a8371d5f40595806f7944a 603 Gene3D G3DSA:2.40.50.100 534 602 1.9E-26 T 22-04-2016 TOLA_RS09380 6d247e14f6a8371d5f40595806f7944a 603 Pfam PF00364 Biotin-requiring enzyme 536 601 2.9E-19 T 22-04-2016 IPR000089 Biotin/lipoyl attachment TOLA_RS09380 6d247e14f6a8371d5f40595806f7944a 603 PANTHER PTHR18866:SF109 1 601 6.9E-249 T 22-04-2016 TOLA_RS09380 6d247e14f6a8371d5f40595806f7944a 603 Pfam PF00682 HMGL-like 5 268 6.4E-51 T 22-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 TOLA_RS09380 6d247e14f6a8371d5f40595806f7944a 603 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 7 598 4.8E-262 T 22-04-2016 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 TOLA_RS09380 6d247e14f6a8371d5f40595806f7944a 603 SUPERFAMILY SSF51569 1 300 4.58E-92 T 22-04-2016 TOLA_RS09380 6d247e14f6a8371d5f40595806f7944a 603 Pfam PF02436 Conserved carboxylase domain 292 483 2.4E-57 T 22-04-2016 IPR003379 Carboxylase, conserved domain TOLA_RS09380 6d247e14f6a8371d5f40595806f7944a 603 SUPERFAMILY SSF51230 530 601 3.93E-22 T 22-04-2016 IPR011053 Single hybrid motif TOLA_RS09380 6d247e14f6a8371d5f40595806f7944a 603 PANTHER PTHR18866 1 601 6.9E-249 T 22-04-2016 TOLA_RS07680 bd8e833bc45acabb0a13abb8b74bb91d 363 Gene3D G3DSA:3.60.15.10 65 362 5.2E-87 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS07680 bd8e833bc45acabb0a13abb8b74bb91d 363 PANTHER PTHR15032 79 363 2.8E-73 T 22-04-2016 TOLA_RS07680 bd8e833bc45acabb0a13abb8b74bb91d 363 SUPERFAMILY SSF56281 101 176 1.7E-31 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS07680 bd8e833bc45acabb0a13abb8b74bb91d 363 SUPERFAMILY SSF56281 203 349 1.7E-31 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS07680 bd8e833bc45acabb0a13abb8b74bb91d 363 PIRSF PIRSF038896 7 353 4.6E-83 T 22-04-2016 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 TOLA_RS07680 bd8e833bc45acabb0a13abb8b74bb91d 363 Pfam PF12706 Beta-lactamase superfamily domain 117 311 1.7E-34 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS07680 bd8e833bc45acabb0a13abb8b74bb91d 363 PANTHER PTHR15032:SF4 79 363 2.8E-73 T 22-04-2016 TOLA_RS04800 bad8294be9e0a669c01d5512748cd821 130 SMART SM00278 82 101 330.0 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TOLA_RS04800 bad8294be9e0a669c01d5512748cd821 130 SMART SM00278 52 71 0.02 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TOLA_RS04800 bad8294be9e0a669c01d5512748cd821 130 Gene3D G3DSA:1.10.150.280 24 96 6.3E-20 T 22-04-2016 TOLA_RS04800 bad8294be9e0a669c01d5512748cd821 130 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 41 104 3.1E-20 T 22-04-2016 IPR004509 Competence protein ComEA, helix-hairpin-helix domain TOLA_RS04800 bad8294be9e0a669c01d5512748cd821 130 PANTHER PTHR21180 24 109 8.4E-26 T 22-04-2016 TOLA_RS04800 bad8294be9e0a669c01d5512748cd821 130 Pfam PF12836 Helix-hairpin-helix motif 41 96 2.7E-21 T 22-04-2016 TOLA_RS04800 bad8294be9e0a669c01d5512748cd821 130 SUPERFAMILY SSF47781 34 105 1.09E-26 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 TOLA_RS01890 066fad1792a5dee95bb242074bf473b5 159 SUPERFAMILY SSF103054 81 157 8.63E-17 T 22-04-2016 IPR023229 Type II secretion system protein M, periplasmic domain TOLA_RS01890 066fad1792a5dee95bb242074bf473b5 159 PIRSF PIRSF006291 1 157 2.3E-43 T 22-04-2016 IPR007690 Type II secretion system, protein M GO:0006858 TOLA_RS01890 066fad1792a5dee95bb242074bf473b5 159 Pfam PF04612 Type II secretion system (T2SS), protein M 2 156 1.2E-38 T 22-04-2016 IPR007690 Type II secretion system, protein M GO:0006858 TOLA_RS01890 066fad1792a5dee95bb242074bf473b5 159 Gene3D G3DSA:3.30.1360.100 82 157 7.2E-23 T 22-04-2016 IPR023229 Type II secretion system protein M, periplasmic domain TOLA_RS02305 65bf8142cd5f3e9e9da86100b5a3d9cc 458 Gene3D G3DSA:3.30.1330.90 11 158 2.6E-52 T 22-04-2016 IPR029009 Allosteric substrate binding domain TOLA_RS02305 65bf8142cd5f3e9e9da86100b5a3d9cc 458 PANTHER PTHR30182 1 456 1.6E-226 T 22-04-2016 TOLA_RS02305 65bf8142cd5f3e9e9da86100b5a3d9cc 458 Pfam PF03313 Serine dehydratase alpha chain 186 452 3.9E-103 T 22-04-2016 IPR005130 Serine dehydratase-like, alpha subunit TOLA_RS02305 65bf8142cd5f3e9e9da86100b5a3d9cc 458 Pfam PF03315 Serine dehydratase beta chain 4 156 1.6E-55 T 22-04-2016 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 TOLA_RS02305 65bf8142cd5f3e9e9da86100b5a3d9cc 458 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 4 455 8.2E-209 T 22-04-2016 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 TOLA_RS02305 65bf8142cd5f3e9e9da86100b5a3d9cc 458 SUPERFAMILY SSF143548 17 157 8.63E-44 T 22-04-2016 IPR029009 Allosteric substrate binding domain TOLA_RS02305 65bf8142cd5f3e9e9da86100b5a3d9cc 458 PANTHER PTHR30182:SF1 1 456 1.6E-226 T 22-04-2016 TOLA_RS13150 0d93214fecbcd12f9780cb47c1f4abcf 186 SUPERFAMILY SSF55846 10 185 5.63E-67 T 22-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 TOLA_RS13150 0d93214fecbcd12f9780cb47c1f4abcf 186 Gene3D G3DSA:3.40.80.10 10 185 7.5E-68 T 22-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 TOLA_RS13150 0d93214fecbcd12f9780cb47c1f4abcf 186 PANTHER PTHR30417 8 186 5.9E-78 T 22-04-2016 TOLA_RS13150 0d93214fecbcd12f9780cb47c1f4abcf 186 PANTHER PTHR30417:SF4 8 186 5.9E-78 T 22-04-2016 TOLA_RS13150 0d93214fecbcd12f9780cb47c1f4abcf 186 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 32 173 2.7E-19 T 22-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 TOLA_RS13150 0d93214fecbcd12f9780cb47c1f4abcf 186 SMART SM00644 22 173 1.7E-54 T 22-04-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 SUPERFAMILY SSF52540 249 439 3.11E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 Pfam PF13638 PIN domain 9 151 1.7E-34 T 22-04-2016 IPR002716 PIN domain TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 SMART SM00670 7 143 1.2E-7 T 22-04-2016 IPR002716 PIN domain TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 PANTHER PTHR30473:SF2 6 184 5.2E-186 T 22-04-2016 TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 PANTHER PTHR30473:SF2 202 460 5.2E-186 T 22-04-2016 TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 Gene3D G3DSA:3.40.50.300 248 458 2.1E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 SUPERFAMILY SSF88723 106 152 3.53E-15 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 SUPERFAMILY SSF88723 7 68 3.53E-15 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 Pfam PF02562 PhoH-like protein 250 454 1.0E-51 T 22-04-2016 IPR003714 PhoH-like protein GO:0005524 TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 SMART SM00382 268 434 0.0033 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 Gene3D G3DSA:3.40.50.1010 106 150 2.7E-16 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 Gene3D G3DSA:3.40.50.1010 8 67 2.7E-16 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 PANTHER PTHR30473 6 184 5.2E-186 T 22-04-2016 TOLA_RS03435 5c14ee7c2e19117f5851f95161af6e9c 460 PANTHER PTHR30473 202 460 5.2E-186 T 22-04-2016 TOLA_RS01355 b8ba034cd1ea2764dff42b7fd4f4ba5c 192 Gene3D G3DSA:3.90.950.10 6 187 4.2E-65 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like TOLA_RS01355 b8ba034cd1ea2764dff42b7fd4f4ba5c 192 PIRSF PIRSF006305 2 191 2.3E-47 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 TOLA_RS01355 b8ba034cd1ea2764dff42b7fd4f4ba5c 192 SUPERFAMILY SSF52972 6 187 1.05E-58 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like TOLA_RS01355 b8ba034cd1ea2764dff42b7fd4f4ba5c 192 PANTHER PTHR11746 126 186 1.0E-12 T 22-04-2016 TOLA_RS01355 b8ba034cd1ea2764dff42b7fd4f4ba5c 192 Hamap MF_00528 Septum formation protein Maf [maf]. 6 192 29.825 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 TOLA_RS01355 b8ba034cd1ea2764dff42b7fd4f4ba5c 192 Pfam PF02545 Maf-like protein 7 187 1.5E-53 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 TOLA_RS01355 b8ba034cd1ea2764dff42b7fd4f4ba5c 192 TIGRFAM TIGR00172 maf: septum formation protein Maf 6 185 3.0E-50 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 TOLA_RS00790 06d43ba923276f1915af9542cb662f0f 167 PANTHER PTHR10458:SF10 1 167 7.8E-100 T 22-04-2016 TOLA_RS00790 06d43ba923276f1915af9542cb662f0f 167 PRINTS PR01576 Peptide deformylase signature 120 149 7.1E-38 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 TOLA_RS00790 06d43ba923276f1915af9542cb662f0f 167 PRINTS PR01576 Peptide deformylase signature 101 119 7.1E-38 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 TOLA_RS00790 06d43ba923276f1915af9542cb662f0f 167 PRINTS PR01576 Peptide deformylase signature 33 62 7.1E-38 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 TOLA_RS00790 06d43ba923276f1915af9542cb662f0f 167 PRINTS PR01576 Peptide deformylase signature 89 100 7.1E-38 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 TOLA_RS00790 06d43ba923276f1915af9542cb662f0f 167 SUPERFAMILY SSF56420 1 161 4.19E-61 T 22-04-2016 IPR023635 Peptide deformylase TOLA_RS00790 06d43ba923276f1915af9542cb662f0f 167 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 160 5.5E-62 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 TOLA_RS00790 06d43ba923276f1915af9542cb662f0f 167 Pfam PF01327 Polypeptide deformylase 5 152 8.2E-51 T 22-04-2016 IPR023635 Peptide deformylase TOLA_RS00790 06d43ba923276f1915af9542cb662f0f 167 Hamap MF_00163 Peptide deformylase [def]. 2 162 30.681 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 TOLA_RS00790 06d43ba923276f1915af9542cb662f0f 167 PANTHER PTHR10458 1 167 7.8E-100 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 TOLA_RS00790 06d43ba923276f1915af9542cb662f0f 167 PIRSF PIRSF004749 1 167 8.6E-55 T 22-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 TOLA_RS00790 06d43ba923276f1915af9542cb662f0f 167 Gene3D G3DSA:3.90.45.10 5 164 6.9E-63 T 22-04-2016 IPR023635 Peptide deformylase TOLA_RS02970 e4f889e02e2963dd56e3101d49dedd0a 307 PANTHER PTHR10584 1 303 1.8E-102 T 22-04-2016 TOLA_RS02970 e4f889e02e2963dd56e3101d49dedd0a 307 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 247 260 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TOLA_RS02970 e4f889e02e2963dd56e3101d49dedd0a 307 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 6 300 8.8E-111 T 22-04-2016 IPR011877 Ribokinase, bacterial type GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|UniPathway: UPA00916 TOLA_RS02970 e4f889e02e2963dd56e3101d49dedd0a 307 PRINTS PR00990 Ribokinase signature 174 189 1.7E-37 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS02970 e4f889e02e2963dd56e3101d49dedd0a 307 PRINTS PR00990 Ribokinase signature 7 28 1.7E-37 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS02970 e4f889e02e2963dd56e3101d49dedd0a 307 PRINTS PR00990 Ribokinase signature 34 53 1.7E-37 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS02970 e4f889e02e2963dd56e3101d49dedd0a 307 PRINTS PR00990 Ribokinase signature 218 229 1.7E-37 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS02970 e4f889e02e2963dd56e3101d49dedd0a 307 PRINTS PR00990 Ribokinase signature 106 119 1.7E-37 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS02970 e4f889e02e2963dd56e3101d49dedd0a 307 Gene3D G3DSA:3.40.1190.20 2 304 5.1E-98 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS02970 e4f889e02e2963dd56e3101d49dedd0a 307 Pfam PF00294 pfkB family carbohydrate kinase 3 294 3.1E-71 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB TOLA_RS02970 e4f889e02e2963dd56e3101d49dedd0a 307 SUPERFAMILY SSF53613 3 303 1.11E-84 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS02970 e4f889e02e2963dd56e3101d49dedd0a 307 PANTHER PTHR10584:SF166 1 303 1.8E-102 T 22-04-2016 TOLA_RS06770 042b4dcecf0aa42ab07d758c30c4f6e0 341 Pfam PF00326 Prolyl oligopeptidase family 260 340 1.7E-5 T 22-04-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TOLA_RS06770 042b4dcecf0aa42ab07d758c30c4f6e0 341 Gene3D G3DSA:3.40.50.1820 132 338 4.2E-36 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS06770 042b4dcecf0aa42ab07d758c30c4f6e0 341 SUPERFAMILY SSF53474 145 323 9.85E-25 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS08340 75891c2b4cedb4f7cf69c75a14c3cef0 371 PANTHER PTHR11228:SF26 27 331 3.1E-86 T 22-04-2016 TOLA_RS08340 75891c2b4cedb4f7cf69c75a14c3cef0 371 SUPERFAMILY SSF102114 84 273 7.72E-13 T 22-04-2016 TOLA_RS08340 75891c2b4cedb4f7cf69c75a14c3cef0 371 Pfam PF04055 Radical SAM superfamily 85 261 8.5E-14 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS08340 75891c2b4cedb4f7cf69c75a14c3cef0 371 PANTHER PTHR11228 27 331 3.1E-86 T 22-04-2016 TOLA_RS08340 75891c2b4cedb4f7cf69c75a14c3cef0 371 Gene3D G3DSA:3.20.20.70 89 273 4.4E-9 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS08340 75891c2b4cedb4f7cf69c75a14c3cef0 371 SMART SM00729 77 307 0.0021 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TOLA_RS10045 dae487cc07a4b4979cf008fb5e67b17d 292 Pfam PF01418 Helix-turn-helix domain, rpiR family 13 84 2.3E-19 T 22-04-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 TOLA_RS10045 dae487cc07a4b4979cf008fb5e67b17d 292 Pfam PF01380 SIS domain 133 261 2.9E-24 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 TOLA_RS10045 dae487cc07a4b4979cf008fb5e67b17d 292 SUPERFAMILY SSF53697 101 282 1.18E-41 T 22-04-2016 TOLA_RS10045 dae487cc07a4b4979cf008fb5e67b17d 292 PANTHER PTHR30514 14 274 4.4E-73 T 22-04-2016 TOLA_RS10045 dae487cc07a4b4979cf008fb5e67b17d 292 Gene3D G3DSA:3.40.50.10490 107 271 4.9E-38 T 22-04-2016 TOLA_RS10045 dae487cc07a4b4979cf008fb5e67b17d 292 PANTHER PTHR30514:SF1 14 274 4.4E-73 T 22-04-2016 TOLA_RS10045 dae487cc07a4b4979cf008fb5e67b17d 292 SUPERFAMILY SSF46689 14 83 3.94E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS10045 dae487cc07a4b4979cf008fb5e67b17d 292 Gene3D G3DSA:1.10.10.10 13 83 2.0E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09900 b51613ebe2b9348e8b9dbe4e5a843348 466 PANTHER PTHR11328 15 463 5.7E-104 T 22-04-2016 TOLA_RS09900 b51613ebe2b9348e8b9dbe4e5a843348 466 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 26 463 5.7E-99 T 22-04-2016 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 TOLA_RS09900 b51613ebe2b9348e8b9dbe4e5a843348 466 SUPERFAMILY SSF103473 27 406 7.85E-26 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS09900 b51613ebe2b9348e8b9dbe4e5a843348 466 Gene3D G3DSA:1.20.1250.20 37 222 5.0E-14 T 22-04-2016 TOLA_RS09900 b51613ebe2b9348e8b9dbe4e5a843348 466 Pfam PF13347 MFS/sugar transport protein 28 447 1.1E-80 T 22-04-2016 TOLA_RS09900 b51613ebe2b9348e8b9dbe4e5a843348 466 PANTHER PTHR11328:SF24 15 463 5.7E-104 T 22-04-2016 TOLA_RS08275 faf560c75fe4d4f5876e77ba0acd30f9 360 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 40 353 3.8E-136 T 22-04-2016 IPR017778 ABC transporter, urea, permease protein, UrtC TOLA_RS08275 faf560c75fe4d4f5876e77ba0acd30f9 360 Pfam PF02653 Branched-chain amino acid transport system / permease component 46 342 2.3E-40 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS08275 faf560c75fe4d4f5876e77ba0acd30f9 360 PANTHER PTHR30482:SF4 118 360 2.0E-160 T 22-04-2016 IPR017778 ABC transporter, urea, permease protein, UrtC TOLA_RS08275 faf560c75fe4d4f5876e77ba0acd30f9 360 PANTHER PTHR30482:SF4 31 90 2.0E-160 T 22-04-2016 IPR017778 ABC transporter, urea, permease protein, UrtC TOLA_RS08275 faf560c75fe4d4f5876e77ba0acd30f9 360 PANTHER PTHR30482 118 360 2.0E-160 T 22-04-2016 TOLA_RS08275 faf560c75fe4d4f5876e77ba0acd30f9 360 PANTHER PTHR30482 31 90 2.0E-160 T 22-04-2016 TOLA_RS00075 b76880c565b81fc8fe5ce2aabc61752e 271 PANTHER PTHR30406:SF1 1 271 3.0E-140 T 22-04-2016 TOLA_RS00075 b76880c565b81fc8fe5ce2aabc61752e 271 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 11 269 3.8E-118 T 22-04-2016 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 TOLA_RS00075 b76880c565b81fc8fe5ce2aabc61752e 271 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 9 266 4.8E-96 T 22-04-2016 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 TOLA_RS00075 b76880c565b81fc8fe5ce2aabc61752e 271 Gene3D G3DSA:1.10.3720.10 15 270 5.2E-50 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00075 b76880c565b81fc8fe5ce2aabc61752e 271 SUPERFAMILY SSF161098 9 262 5.49E-55 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00075 b76880c565b81fc8fe5ce2aabc61752e 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 267 5.4E-16 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00075 b76880c565b81fc8fe5ce2aabc61752e 271 PANTHER PTHR30406 1 271 3.0E-140 T 22-04-2016 TOLA_RS04480 5162a60c7459a352bb6fa51f0745d22f 226 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS04480 5162a60c7459a352bb6fa51f0745d22f 226 SMART SM00382 35 221 5.6E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS04480 5162a60c7459a352bb6fa51f0745d22f 226 Gene3D G3DSA:3.40.50.300 6 225 4.6E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04480 5162a60c7459a352bb6fa51f0745d22f 226 PANTHER PTHR24220 8 224 3.2E-100 T 22-04-2016 TOLA_RS04480 5162a60c7459a352bb6fa51f0745d22f 226 SUPERFAMILY SSF52540 6 224 5.71E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04480 5162a60c7459a352bb6fa51f0745d22f 226 PANTHER PTHR24220:SF509 8 224 3.2E-100 T 22-04-2016 TOLA_RS04480 5162a60c7459a352bb6fa51f0745d22f 226 Pfam PF00005 ABC transporter 26 172 7.7E-35 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS05885 80345a1dad84445df8a76f4d15211f0f 443 Gene3D G3DSA:3.90.550.10 66 318 2.7E-26 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS05885 80345a1dad84445df8a76f4d15211f0f 443 PANTHER PTHR10859 51 425 1.7E-60 T 22-04-2016 TOLA_RS05885 80345a1dad84445df8a76f4d15211f0f 443 Pfam PF13641 Glycosyltransferase like family 2 68 299 1.6E-20 T 22-04-2016 TOLA_RS05885 80345a1dad84445df8a76f4d15211f0f 443 SUPERFAMILY SSF53448 62 353 4.28E-36 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS05885 80345a1dad84445df8a76f4d15211f0f 443 PANTHER PTHR10859:SF92 51 425 1.7E-60 T 22-04-2016 TOLA_RS00980 22ebfefe8b536cda956bae4549fa3122 402 SUPERFAMILY SSF102645 186 398 1.83E-78 T 22-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 TOLA_RS00980 22ebfefe8b536cda956bae4549fa3122 402 PANTHER PTHR14359:SF20 1 402 4.3E-194 T 22-04-2016 TOLA_RS00980 22ebfefe8b536cda956bae4549fa3122 402 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 393 1.1E-153 T 22-04-2016 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|UniPathway: UPA00241|UniPathway: UPA00241 TOLA_RS00980 22ebfefe8b536cda956bae4549fa3122 402 Gene3D G3DSA:3.40.50.10300 185 399 5.5E-90 T 22-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 TOLA_RS00980 22ebfefe8b536cda956bae4549fa3122 402 PANTHER PTHR14359 1 402 4.3E-194 T 22-04-2016 TOLA_RS00980 22ebfefe8b536cda956bae4549fa3122 402 SUPERFAMILY SSF52507 3 181 3.92E-63 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 TOLA_RS00980 22ebfefe8b536cda956bae4549fa3122 402 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 188 369 2.5E-74 T 22-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 TOLA_RS00980 22ebfefe8b536cda956bae4549fa3122 402 Pfam PF02441 Flavoprotein 6 134 1.0E-33 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 TOLA_RS00980 22ebfefe8b536cda956bae4549fa3122 402 Gene3D G3DSA:3.40.50.1950 2 184 1.3E-65 T 22-04-2016 IPR003382 Flavoprotein GO:0003824 TOLA_RS15345 286042c7cf7ffa0a7ae46dae1455849c 123 Pfam PF11604 Copper binding periplasmic protein CusF 55 121 1.3E-22 T 22-04-2016 IPR021647 Copper binding periplasmic protein CusF TOLA_RS13355 394ff28b0afed7a0653a4a0798655e94 702 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 286 698 3.0E-152 T 22-04-2016 IPR013355 Type IV pilus secretin PilQ GO:0009297|GO:0009306 TOLA_RS13355 394ff28b0afed7a0653a4a0798655e94 702 PRINTS PR00811 Bacterial general secretion pathway protein D signature 686 700 7.1E-17 T 22-04-2016 IPR001775 GspD/PilQ family TOLA_RS13355 394ff28b0afed7a0653a4a0798655e94 702 PRINTS PR00811 Bacterial general secretion pathway protein D signature 449 459 7.1E-17 T 22-04-2016 IPR001775 GspD/PilQ family TOLA_RS13355 394ff28b0afed7a0653a4a0798655e94 702 PRINTS PR00811 Bacterial general secretion pathway protein D signature 535 559 7.1E-17 T 22-04-2016 IPR001775 GspD/PilQ family TOLA_RS13355 394ff28b0afed7a0653a4a0798655e94 702 PRINTS PR00811 Bacterial general secretion pathway protein D signature 663 681 7.1E-17 T 22-04-2016 IPR001775 GspD/PilQ family TOLA_RS13355 394ff28b0afed7a0653a4a0798655e94 702 Pfam PF00263 Bacterial type II and III secretion system protein 539 698 1.1E-46 T 22-04-2016 IPR004846 Type II/III secretion system GO:0009306 TOLA_RS13355 394ff28b0afed7a0653a4a0798655e94 702 Pfam PF07660 Secretin and TonB N terminus short domain 313 358 8.0E-7 T 22-04-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TOLA_RS13355 394ff28b0afed7a0653a4a0798655e94 702 Pfam PF03958 Bacterial type II/III secretion system short domain 385 449 3.1E-12 T 22-04-2016 IPR005644 NolW-like TOLA_RS13355 394ff28b0afed7a0653a4a0798655e94 702 PANTHER PTHR30604 158 698 2.1E-115 T 22-04-2016 TOLA_RS13355 394ff28b0afed7a0653a4a0798655e94 702 SMART SM00965 311 359 1.5E-8 T 22-04-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 TOLA_RS09505 dd7b7a084e7a5c8cec5f88b1ac061ab9 118 Pfam PF06923 Glucitol operon activator protein (GutM) 6 110 6.0E-29 T 22-04-2016 IPR009693 Glucitol operon activator TOLA_RS07965 4331c8da5bec905b9883d4efbf259eac 99 PANTHER PTHR33404 1 85 3.0E-27 T 22-04-2016 TOLA_RS07965 4331c8da5bec905b9883d4efbf259eac 99 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 83 9.0E-32 T 22-04-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 TOLA_RS07965 4331c8da5bec905b9883d4efbf259eac 99 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 86 20.73 T 22-04-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 TOLA_RS07965 4331c8da5bec905b9883d4efbf259eac 99 Gene3D G3DSA:3.30.1070.10 34 87 5.3E-23 T 22-04-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 TOLA_RS07965 4331c8da5bec905b9883d4efbf259eac 99 Pfam PF03776 Septum formation topological specificity factor MinE 15 82 8.0E-26 T 22-04-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 TOLA_RS07965 4331c8da5bec905b9883d4efbf259eac 99 SUPERFAMILY SSF55229 34 85 5.36E-16 T 22-04-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 TOLA_RS01595 df23aae91cab83366366ca62501b6166 276 Gene3D G3DSA:1.10.10.10 171 268 9.2E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01595 df23aae91cab83366366ca62501b6166 276 SUPERFAMILY SSF46785 172 268 2.69E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01595 df23aae91cab83366366ca62501b6166 276 Pfam PF08722 TnsA endonuclease N terminal 74 165 1.2E-25 T 22-04-2016 IPR014833 TnsA endonuclease, N-terminal TOLA_RS01595 df23aae91cab83366366ca62501b6166 276 Gene3D G3DSA:3.40.1350.10 9 168 3.7E-66 T 22-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 TOLA_RS01595 df23aae91cab83366366ca62501b6166 276 SUPERFAMILY SSF52980 9 168 2.57E-60 T 22-04-2016 IPR011335 Restriction endonuclease type II-like TOLA_RS01595 df23aae91cab83366366ca62501b6166 276 Pfam PF08721 TnsA endonuclease C terminal 167 247 3.3E-15 T 22-04-2016 IPR014832 TnsA endonuclease C-terminal TOLA_RS16225 93ea09c63d31610a2c1cbe321eaeb522 270 SUPERFAMILY SSF51905 7 270 2.14E-37 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS16225 93ea09c63d31610a2c1cbe321eaeb522 270 Gene3D G3DSA:3.50.50.60 147 264 1.5E-15 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS16225 93ea09c63d31610a2c1cbe321eaeb522 270 Gene3D G3DSA:3.40.50.720 8 146 9.6E-39 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS16225 93ea09c63d31610a2c1cbe321eaeb522 270 PANTHER PTHR22912 1 237 1.2E-20 T 22-04-2016 TOLA_RS16225 93ea09c63d31610a2c1cbe321eaeb522 270 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 36 1.8E-7 T 22-04-2016 TOLA_RS16225 93ea09c63d31610a2c1cbe321eaeb522 270 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 95 109 1.8E-7 T 22-04-2016 TOLA_RS16225 93ea09c63d31610a2c1cbe321eaeb522 270 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 241 7.7E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS16225 93ea09c63d31610a2c1cbe321eaeb522 270 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 94 112 1.5E-18 T 22-04-2016 TOLA_RS16225 93ea09c63d31610a2c1cbe321eaeb522 270 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 218 234 1.5E-18 T 22-04-2016 TOLA_RS16225 93ea09c63d31610a2c1cbe321eaeb522 270 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 1.5E-18 T 22-04-2016 TOLA_RS16225 93ea09c63d31610a2c1cbe321eaeb522 270 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.5E-18 T 22-04-2016 TOLA_RS00990 2f2b388da6cfae9ec4d6529bdd71613f 213 Pfam PF00156 Phosphoribosyl transferase domain 42 161 2.1E-12 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 TOLA_RS00990 2f2b388da6cfae9ec4d6529bdd71613f 213 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 213 36.218 T 22-04-2016 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS00990 2f2b388da6cfae9ec4d6529bdd71613f 213 SUPERFAMILY SSF53271 2 210 4.97E-49 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS00990 2f2b388da6cfae9ec4d6529bdd71613f 213 PANTHER PTHR19278 1 213 2.0E-138 T 22-04-2016 TOLA_RS00990 2f2b388da6cfae9ec4d6529bdd71613f 213 Gene3D G3DSA:3.40.50.2020 7 212 1.9E-82 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS00990 2f2b388da6cfae9ec4d6529bdd71613f 213 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 10 187 1.4E-67 T 22-04-2016 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS00990 2f2b388da6cfae9ec4d6529bdd71613f 213 PANTHER PTHR19278:SF36 1 213 2.0E-138 T 22-04-2016 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 Gene3D G3DSA:3.40.192.10 7 140 2.3E-50 T 22-04-2016 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 SUPERFAMILY SSF51735 123 280 1.23E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 PANTHER PTHR10025 1 283 2.7E-167 T 22-04-2016 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 1.1E-84 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 1.1E-84 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 239 255 1.1E-84 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 1.1E-84 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 1.1E-84 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 1.1E-84 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 1.1E-84 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 37.839 T 22-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 Gene3D G3DSA:3.40.50.720 141 264 5.2E-50 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 76 101 - T 22-04-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 SUPERFAMILY SSF53223 1 122 3.07E-39 T 22-04-2016 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 281 1.1E-67 T 22-04-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 260 268 - T 22-04-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 TOLA_RS09755 b2810cb722819ec512da555e036202ab 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 121 2.9E-38 T 22-04-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 TOLA_RS07625 daf00b5dc6f42e0513ad603cd532d3c2 306 Pfam PF03466 LysR substrate binding domain 87 287 7.1E-26 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS07625 daf00b5dc6f42e0513ad603cd532d3c2 306 PANTHER PTHR30126 1 302 1.7E-53 T 22-04-2016 TOLA_RS07625 daf00b5dc6f42e0513ad603cd532d3c2 306 PANTHER PTHR30126:SF30 1 302 1.7E-53 T 22-04-2016 TOLA_RS07625 daf00b5dc6f42e0513ad603cd532d3c2 306 Gene3D G3DSA:1.10.10.10 1 84 1.1E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07625 daf00b5dc6f42e0513ad603cd532d3c2 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.5E-15 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07625 daf00b5dc6f42e0513ad603cd532d3c2 306 SUPERFAMILY SSF46785 3 84 1.49E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07625 daf00b5dc6f42e0513ad603cd532d3c2 306 Gene3D G3DSA:3.40.190.10 88 193 2.8E-13 T 22-04-2016 TOLA_RS07625 daf00b5dc6f42e0513ad603cd532d3c2 306 SUPERFAMILY SSF53850 85 292 2.64E-26 T 22-04-2016 TOLA_RS08490 cb1222d04b3e98675521120666bbbaf9 239 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 25 236 26.324 T 22-04-2016 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 UniPathway: UPA00148 TOLA_RS08490 cb1222d04b3e98675521120666bbbaf9 239 PANTHER PTHR34229 26 232 6.6E-104 T 22-04-2016 TOLA_RS08490 cb1222d04b3e98675521120666bbbaf9 239 PANTHER PTHR34229:SF2 26 232 6.6E-104 T 22-04-2016 TOLA_RS08490 cb1222d04b3e98675521120666bbbaf9 239 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 26 231 8.3E-49 T 22-04-2016 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 UniPathway: UPA00148 TOLA_RS08490 cb1222d04b3e98675521120666bbbaf9 239 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 25 235 3.5E-95 T 22-04-2016 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 UniPathway: UPA00148 TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 Gene3D G3DSA:3.30.70.920 64 160 2.1E-33 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 PANTHER PTHR30154:SF0 3 161 3.3E-100 T 22-04-2016 TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 ProSitePatterns PS00519 AsnC-type HTH domain signature. 29 55 - T 22-04-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 SUPERFAMILY SSF46785 11 69 2.94E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 SUPERFAMILY SSF54909 73 157 1.31E-22 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 Pfam PF01037 Lrp/AsnC ligand binding domain 77 151 2.3E-24 T 22-04-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 PANTHER PTHR30154 3 161 3.3E-100 T 22-04-2016 TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 Gene3D G3DSA:1.10.10.10 12 63 1.2E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 Pfam PF13412 Winged helix-turn-helix DNA-binding 11 58 2.0E-21 T 22-04-2016 TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 38 6.1E-23 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 57 6.1E-23 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 11 27 6.1E-23 T 22-04-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 TOLA_RS11765 54cb08c037dee0c48a5025abe3de6f30 163 SMART SM00344 11 120 2.1E-54 T 22-04-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TOLA_RS14260 7c57c4f9a33422e5f29de1fe87323168 167 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 162 26.914 T 22-04-2016 IPR022973 Ribosomal protein L10 TOLA_RS14260 7c57c4f9a33422e5f29de1fe87323168 167 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 22-04-2016 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS14260 7c57c4f9a33422e5f29de1fe87323168 167 Pfam PF00466 Ribosomal protein L10 6 101 4.7E-25 T 22-04-2016 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TOLA_RS14260 7c57c4f9a33422e5f29de1fe87323168 167 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 78 155 1.0E-4 T 22-04-2016 TOLA_RS14260 7c57c4f9a33422e5f29de1fe87323168 167 SUPERFAMILY SSF160369 5 161 3.4E-48 T 22-04-2016 TOLA_RS14260 7c57c4f9a33422e5f29de1fe87323168 167 PANTHER PTHR11560 1 164 5.7E-58 T 22-04-2016 TOLA_RS00605 39a1c12a75d472e4bc3c14b22879ce1c 166 PANTHER PTHR13718 10 164 5.2E-76 T 22-04-2016 IPR000851 Ribosomal protein S5 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00605 39a1c12a75d472e4bc3c14b22879ce1c 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 10 163 5.5E-70 T 22-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TOLA_RS00605 39a1c12a75d472e4bc3c14b22879ce1c 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 35.164 T 22-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TOLA_RS00605 39a1c12a75d472e4bc3c14b22879ce1c 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 22-04-2016 IPR018192 Ribosomal protein S5, N-terminal, conserved site TOLA_RS00605 39a1c12a75d472e4bc3c14b22879ce1c 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 1.7E-29 T 22-04-2016 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 TOLA_RS00605 39a1c12a75d472e4bc3c14b22879ce1c 166 Gene3D G3DSA:3.30.230.10 78 158 8.8E-34 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS00605 39a1c12a75d472e4bc3c14b22879ce1c 166 Gene3D G3DSA:3.30.160.20 10 73 2.2E-30 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain TOLA_RS00605 39a1c12a75d472e4bc3c14b22879ce1c 166 SUPERFAMILY SSF54768 9 76 1.26E-23 T 22-04-2016 TOLA_RS00605 39a1c12a75d472e4bc3c14b22879ce1c 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 1.8E-30 T 22-04-2016 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 TOLA_RS00605 39a1c12a75d472e4bc3c14b22879ce1c 166 SUPERFAMILY SSF54211 79 158 3.03E-27 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS00150 b97d36427562bfb6fec570716e769587 198 Gene3D G3DSA:3.30.420.10 34 191 2.1E-36 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS00150 b97d36427562bfb6fec570716e769587 198 PANTHER PTHR32552 28 198 6.7E-38 T 22-04-2016 TOLA_RS00150 b97d36427562bfb6fec570716e769587 198 SUPERFAMILY SSF53098 34 195 5.94E-41 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS00150 b97d36427562bfb6fec570716e769587 198 Pfam PF00665 Integrase core domain 38 152 7.5E-31 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 TOLA_RS03610 a29a0a55cc33afeb9996d11d593908e5 588 SUPERFAMILY SSF55874 7 199 6.93E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS03610 a29a0a55cc33afeb9996d11d593908e5 588 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 22 159 3.0E-27 T 22-04-2016 TOLA_RS03610 a29a0a55cc33afeb9996d11d593908e5 588 Gene3D G3DSA:3.30.565.10 18 171 5.9E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS02830 ee6efe7e26d1f0d6e253a257e24642a5 173 Pfam PF06271 RDD family 26 161 3.4E-17 T 22-04-2016 IPR010432 RDD TOLA_RS02830 ee6efe7e26d1f0d6e253a257e24642a5 173 PANTHER PTHR36115 23 166 3.8E-20 T 22-04-2016 TOLA_RS02830 ee6efe7e26d1f0d6e253a257e24642a5 173 PANTHER PTHR36115:SF2 23 166 3.8E-20 T 22-04-2016 TOLA_RS07600 f19cc5885cae319285f42e9351e8626c 305 Gene3D G3DSA:1.10.10.10 4 80 7.7E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07600 f19cc5885cae319285f42e9351e8626c 305 PANTHER PTHR30537:SF5 1 305 7.6E-61 T 22-04-2016 TOLA_RS07600 f19cc5885cae319285f42e9351e8626c 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 6.8E-12 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07600 f19cc5885cae319285f42e9351e8626c 305 SUPERFAMILY SSF46785 5 82 1.82E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07600 f19cc5885cae319285f42e9351e8626c 305 Pfam PF03466 LysR substrate binding domain 91 287 3.5E-27 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS07600 f19cc5885cae319285f42e9351e8626c 305 PANTHER PTHR30537 1 305 7.6E-61 T 22-04-2016 TOLA_RS07600 f19cc5885cae319285f42e9351e8626c 305 Gene3D G3DSA:3.40.190.10 91 171 7.6E-15 T 22-04-2016 TOLA_RS07600 f19cc5885cae319285f42e9351e8626c 305 Gene3D G3DSA:3.40.190.10 172 258 6.9E-21 T 22-04-2016 TOLA_RS07600 f19cc5885cae319285f42e9351e8626c 305 SUPERFAMILY SSF53850 91 293 8.87E-32 T 22-04-2016 TOLA_RS05115 7fd4803c8804396ddf3d61658bbeec78 391 PANTHER PTHR30006:SF12 224 391 1.4E-142 T 22-04-2016 TOLA_RS05115 7fd4803c8804396ddf3d61658bbeec78 391 PANTHER PTHR30006:SF12 4 206 1.4E-142 T 22-04-2016 TOLA_RS05115 7fd4803c8804396ddf3d61658bbeec78 391 Pfam PF13416 Bacterial extracellular solute-binding protein 53 341 2.9E-25 T 22-04-2016 TOLA_RS05115 7fd4803c8804396ddf3d61658bbeec78 391 Gene3D G3DSA:3.40.190.10 159 313 5.3E-12 T 22-04-2016 TOLA_RS05115 7fd4803c8804396ddf3d61658bbeec78 391 PANTHER PTHR30006 224 391 1.4E-142 T 22-04-2016 TOLA_RS05115 7fd4803c8804396ddf3d61658bbeec78 391 PANTHER PTHR30006 4 206 1.4E-142 T 22-04-2016 TOLA_RS05115 7fd4803c8804396ddf3d61658bbeec78 391 SUPERFAMILY SSF53850 32 388 6.14E-38 T 22-04-2016 TOLA_RS05115 7fd4803c8804396ddf3d61658bbeec78 391 Gene3D G3DSA:3.40.190.10 314 338 5.8E-20 T 22-04-2016 TOLA_RS05115 7fd4803c8804396ddf3d61658bbeec78 391 Gene3D G3DSA:3.40.190.10 31 151 5.8E-20 T 22-04-2016 TOLA_RS05115 7fd4803c8804396ddf3d61658bbeec78 391 PIRSF PIRSF029172 1 391 1.8E-167 T 22-04-2016 IPR027020 Protein ynjB TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 Gene3D G3DSA:3.20.20.80 3 461 5.3E-169 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 Pfam PF00232 Glycosyl hydrolase family 1 3 464 5.1E-178 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 287 301 6.9E-20 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 368 376 6.9E-20 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 388 399 6.9E-20 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 409 426 6.9E-20 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 433 445 6.9E-20 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 368 376 - T 22-04-2016 IPR018120 Glycoside hydrolase family 1, active site TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 PANTHER PTHR10353:SF60 2 467 1.8E-207 T 22-04-2016 TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 22-04-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 SUPERFAMILY SSF51445 4 464 4.04E-170 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 TIGRFAM TIGR03356 BGL: beta-galactosidase 4 456 3.9E-156 T 22-04-2016 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7089|MetaCyc: PWY-7091|MetaCyc: PWY-7092 TOLA_RS15320 05ac201e7e352d67cb50df49e1ee89b0 467 PANTHER PTHR10353 2 467 1.8E-207 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS07265 c0809beae932def5fe8a3ae3c9d86c09 181 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 14 181 3.8E-92 T 22-04-2016 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 TOLA_RS07265 c0809beae932def5fe8a3ae3c9d86c09 181 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 11 181 51.087 T 22-04-2016 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 TOLA_RS07265 c0809beae932def5fe8a3ae3c9d86c09 181 Gene3D G3DSA:3.10.129.10 12 177 1.8E-59 T 22-04-2016 IPR029069 HotDog domain TOLA_RS07265 c0809beae932def5fe8a3ae3c9d86c09 181 SUPERFAMILY SSF54637 13 178 7.46E-56 T 22-04-2016 IPR029069 HotDog domain TOLA_RS07265 c0809beae932def5fe8a3ae3c9d86c09 181 Pfam PF07977 FabA-like domain 38 167 2.7E-51 T 22-04-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 Pfam PF07724 AAA domain (Cdc48 subfamily) 490 651 3.2E-49 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 Gene3D G3DSA:3.40.50.300 446 667 1.3E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 Gene3D G3DSA:1.10.8.60 355 439 7.1E-30 T 22-04-2016 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 599 613 1.1E-36 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 566 584 1.1E-36 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 537 555 1.1E-36 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 495 513 1.1E-36 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 SUPERFAMILY SSF81923 1 142 1.18E-58 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 215 306 9.7E-11 T 22-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 SMART SM01086 657 746 2.4E-37 T 22-04-2016 IPR019489 Clp ATPase, C-terminal TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 522 540 - T 22-04-2016 IPR028299 ClpA/B, conserved site 2 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 SUPERFAMILY SSF52540 173 424 6.59E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 59 4.6E-11 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 657 737 3.3E-24 T 22-04-2016 IPR019489 Clp ATPase, C-terminal TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 Gene3D G3DSA:1.10.1780.10 1 142 2.4E-42 T 22-04-2016 IPR004176 Clp, N-terminal GO:0019538 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 738 0.0 T 22-04-2016 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 Gene3D G3DSA:1.10.8.60 668 752 2.6E-32 T 22-04-2016 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 PANTHER PTHR11638 1 758 0.0 T 22-04-2016 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 PANTHER PTHR11638:SF111 1 758 0.0 T 22-04-2016 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 SUPERFAMILY SSF52540 441 746 5.18E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 306 318 - T 22-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 Gene3D G3DSA:3.40.50.300 172 353 1.1E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 SMART SM00382 210 355 2.1E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS11795 d39878fd37cac90b20bb9e47c2e45942 758 SMART SM00382 491 658 4.3E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS08485 6abf1759b3cff12d92eb6b4d529212ac 94 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 94 41.514 T 22-04-2016 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 UniPathway: UPA00148 TOLA_RS08485 6abf1759b3cff12d92eb6b4d529212ac 94 TIGRFAM TIGR01165 cbiN: cobalt transport protein 1 85 4.0E-35 T 22-04-2016 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 UniPathway: UPA00148 TOLA_RS08485 6abf1759b3cff12d92eb6b4d529212ac 94 PANTHER PTHR38662 1 87 9.1E-34 T 22-04-2016 TOLA_RS08485 6abf1759b3cff12d92eb6b4d529212ac 94 Pfam PF02553 Cobalt transport protein component CbiN 5 69 4.4E-28 T 22-04-2016 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 UniPathway: UPA00148 TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 Gene3D G3DSA:1.10.1660.10 61 136 3.1E-33 T 22-04-2016 TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 SUPERFAMILY SSF46955 6 131 6.59E-41 T 22-04-2016 IPR009061 Putative DNA-binding domain TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 Pfam PF00376 MerR family regulatory protein 7 44 3.6E-17 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 2.3E-13 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 2.3E-13 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 2.3E-13 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 PANTHER PTHR30204:SF16 1 132 1.7E-60 T 22-04-2016 TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 PANTHER PTHR30204 1 132 1.7E-60 T 22-04-2016 TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 SMART SM00422 6 75 3.0E-34 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 7 131 4.2E-52 T 22-04-2016 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 Pfam PF09278 MerR, DNA binding 49 113 2.0E-21 T 22-04-2016 IPR015358 Transcription regulator MerR, DNA binding TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 ProSitePatterns PS00552 MerR-type HTH domain signature. 9 31 - T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TOLA_RS03045 d5caa825998461d66ef621ec12a3f95a 145 Gene3D G3DSA:1.10.1660.10 5 60 8.2E-28 T 22-04-2016 TOLA_RS09410 5cf7f79856dbf2d9a08f6ae15a7a985d 284 Gene3D G3DSA:2.160.20.10 150 234 2.7E-6 T 22-04-2016 IPR012334 Pectin lyase fold TOLA_RS09410 5cf7f79856dbf2d9a08f6ae15a7a985d 284 Gene3D G3DSA:2.160.20.10 54 118 2.7E-6 T 22-04-2016 IPR012334 Pectin lyase fold TOLA_RS09410 5cf7f79856dbf2d9a08f6ae15a7a985d 284 SUPERFAMILY SSF51126 54 233 3.69E-15 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor TOLA_RS09410 5cf7f79856dbf2d9a08f6ae15a7a985d 284 Pfam PF12541 Protein of unknown function (DUF3737) 3 277 1.2E-120 T 22-04-2016 IPR022208 Protein of unknown function DUF3737 TOLA_RS12635 ed6da79a20a17abcdd12b5cf64d861b8 213 SUPERFAMILY SSF53850 10 192 9.91E-22 T 22-04-2016 TOLA_RS12635 ed6da79a20a17abcdd12b5cf64d861b8 213 Pfam PF03466 LysR substrate binding domain 10 192 1.3E-20 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS12635 ed6da79a20a17abcdd12b5cf64d861b8 213 PANTHER PTHR30346 11 210 1.0E-18 T 22-04-2016 TOLA_RS12635 ed6da79a20a17abcdd12b5cf64d861b8 213 Gene3D G3DSA:3.40.190.10 94 179 2.9E-4 T 22-04-2016 TOLA_RS12635 ed6da79a20a17abcdd12b5cf64d861b8 213 Gene3D G3DSA:3.40.190.10 10 93 1.7E-14 T 22-04-2016 TOLA_RS11865 9ab3a7cdb1858a73c2221007a6244894 208 Pfam PF04205 FMN-binding domain 103 193 2.0E-18 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 TOLA_RS11865 9ab3a7cdb1858a73c2221007a6244894 208 PIRSF PIRSF006091 8 207 1.1E-63 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 TOLA_RS11865 9ab3a7cdb1858a73c2221007a6244894 208 PANTHER PTHR36118:SF1 9 201 8.3E-48 T 22-04-2016 TOLA_RS11865 9ab3a7cdb1858a73c2221007a6244894 208 SMART SM00900 103 195 5.5E-34 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 TOLA_RS11865 9ab3a7cdb1858a73c2221007a6244894 208 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 18 196 6.5E-54 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 TOLA_RS11865 9ab3a7cdb1858a73c2221007a6244894 208 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 10 197 24.87 T 22-04-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 TOLA_RS11865 9ab3a7cdb1858a73c2221007a6244894 208 PANTHER PTHR36118 9 201 8.3E-48 T 22-04-2016 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 Gene3D G3DSA:2.40.240.10 463 549 2.2E-32 T 22-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 551 53.381 T 22-04-2016 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 PANTHER PTHR11451 7 247 3.6E-235 T 22-04-2016 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 PANTHER PTHR11451 267 551 3.6E-235 T 22-04-2016 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 28 337 1.2E-125 T 22-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 PANTHER PTHR11451:SF29 7 247 3.6E-235 T 22-04-2016 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 PANTHER PTHR11451:SF29 267 551 3.6E-235 T 22-04-2016 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 PRINTS PR00987 Glutamyl-tRNA synthetase signature 60 73 1.1E-9 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 PRINTS PR00987 Glutamyl-tRNA synthetase signature 31 43 1.1E-9 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 PRINTS PR00987 Glutamyl-tRNA synthetase signature 45 56 1.1E-9 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 PRINTS PR00987 Glutamyl-tRNA synthetase signature 210 220 1.1E-9 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 34 45 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 SUPERFAMILY SSF50715 340 549 1.57E-74 T 22-04-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: REACT_71 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 Gene3D G3DSA:2.40.240.10 348 462 2.2E-47 T 22-04-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 SUPERFAMILY SSF52374 10 337 1.63E-103 T 22-04-2016 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 Gene3D G3DSA:3.40.50.620 28 96 2.4E-43 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 Gene3D G3DSA:3.40.50.620 212 262 2.4E-43 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 28 551 2.1E-287 T 22-04-2016 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 340 530 1.1E-59 T 22-04-2016 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: REACT_71 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 Gene3D G3DSA:3.90.800.10 101 209 1.8E-47 T 22-04-2016 TOLA_RS10845 fcbd8d51e3bb60ab4273b4bf1601f03f 553 Gene3D G3DSA:1.10.1160.10 263 338 3.2E-39 T 22-04-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 TOLA_RS14045 2f65abb118a9b145e4a477163f34480a 372 Gene3D G3DSA:3.40.1130.10 67 246 7.0E-8 T 22-04-2016 TOLA_RS14045 2f65abb118a9b145e4a477163f34480a 372 PANTHER PTHR30068 7 349 2.3E-146 T 22-04-2016 TOLA_RS14045 2f65abb118a9b145e4a477163f34480a 372 PANTHER PTHR30068:SF3 7 349 2.3E-146 T 22-04-2016 TOLA_RS14045 2f65abb118a9b145e4a477163f34480a 372 Pfam PF01553 Acyltransferase 95 244 2.6E-11 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TOLA_RS14045 2f65abb118a9b145e4a477163f34480a 372 SUPERFAMILY SSF69593 94 322 1.96E-11 T 22-04-2016 TOLA_RS15665 d8c0bade0549fddea7cbe453377f498f 293 PANTHER PTHR10983:SF15 7 292 4.9E-117 T 22-04-2016 TOLA_RS15665 d8c0bade0549fddea7cbe453377f498f 293 SUPERFAMILY SSF69593 23 231 1.05E-26 T 22-04-2016 TOLA_RS15665 d8c0bade0549fddea7cbe453377f498f 293 Pfam PF01553 Acyltransferase 75 227 3.6E-12 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TOLA_RS15665 d8c0bade0549fddea7cbe453377f498f 293 SMART SM00563 88 230 6.1E-18 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TOLA_RS15665 d8c0bade0549fddea7cbe453377f498f 293 PANTHER PTHR10983 7 292 4.9E-117 T 22-04-2016 TOLA_RS05410 77cec3f75910a026899274c30e114b28 416 PANTHER PTHR24031:SF261 1 365 8.0E-172 T 22-04-2016 TOLA_RS05410 77cec3f75910a026899274c30e114b28 416 Pfam PF00271 Helicase conserved C-terminal domain 235 337 5.9E-29 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS05410 77cec3f75910a026899274c30e114b28 416 SMART SM00490 256 337 2.4E-33 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS05410 77cec3f75910a026899274c30e114b28 416 Gene3D G3DSA:3.40.50.300 1 209 6.2E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05410 77cec3f75910a026899274c30e114b28 416 Pfam PF00270 DEAD/DEAH box helicase 25 191 1.7E-49 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS05410 77cec3f75910a026899274c30e114b28 416 PANTHER PTHR24031 1 365 8.0E-172 T 22-04-2016 TOLA_RS05410 77cec3f75910a026899274c30e114b28 416 SUPERFAMILY SSF52540 73 356 2.54E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05410 77cec3f75910a026899274c30e114b28 416 SMART SM00487 20 220 1.8E-58 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS05410 77cec3f75910a026899274c30e114b28 416 Gene3D G3DSA:3.40.50.300 210 366 8.5E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05410 77cec3f75910a026899274c30e114b28 416 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 151 159 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TOLA_RS01845 7621e869c8599e8d7551ef9bb2956f1f 729 PANTHER PTHR11070 6 729 4.9E-242 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS01845 7621e869c8599e8d7551ef9bb2956f1f 729 Pfam PF13361 UvrD-like helicase C-terminal domain 280 619 3.3E-73 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TOLA_RS01845 7621e869c8599e8d7551ef9bb2956f1f 729 TIGRFAM TIGR01075 uvrD: DNA helicase II 6 727 0.0 T 22-04-2016 IPR005753 DNA helicase, ATP-dependent, UvrD type GO:0004003|GO:0005737|GO:0006268 TOLA_RS01845 7621e869c8599e8d7551ef9bb2956f1f 729 SUPERFAMILY SSF52540 5 645 1.65E-178 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01845 7621e869c8599e8d7551ef9bb2956f1f 729 Gene3D G3DSA:1.10.10.160 118 193 9.7E-23 T 22-04-2016 IPR013986 DExx box DNA helicase domain TOLA_RS01845 7621e869c8599e8d7551ef9bb2956f1f 729 Gene3D G3DSA:3.40.50.300 555 645 3.4E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01845 7621e869c8599e8d7551ef9bb2956f1f 729 Gene3D G3DSA:3.40.50.300 289 390 3.4E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01845 7621e869c8599e8d7551ef9bb2956f1f 729 Gene3D G3DSA:3.40.50.300 194 288 1.7E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01845 7621e869c8599e8d7551ef9bb2956f1f 729 Gene3D G3DSA:3.40.50.300 4 114 1.7E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01845 7621e869c8599e8d7551ef9bb2956f1f 729 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 275 2.3E-73 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TOLA_RS01845 7621e869c8599e8d7551ef9bb2956f1f 729 Gene3D G3DSA:1.10.486.10 391 544 2.2E-47 T 22-04-2016 TOLA_RS01845 7621e869c8599e8d7551ef9bb2956f1f 729 PANTHER PTHR11070:SF7 6 729 4.9E-242 T 22-04-2016 TOLA_RS05180 aaffd3de216df8dba627879532e80322 182 PANTHER PTHR30173 15 158 4.7E-22 T 22-04-2016 TOLA_RS05180 aaffd3de216df8dba627879532e80322 182 Pfam PF04542 Sigma-70 region 2 21 81 7.0E-8 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS05180 aaffd3de216df8dba627879532e80322 182 Pfam PF08281 Sigma-70, region 4 104 156 1.2E-9 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS05180 aaffd3de216df8dba627879532e80322 182 SUPERFAMILY SSF88946 16 93 4.71E-13 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS05180 aaffd3de216df8dba627879532e80322 182 SUPERFAMILY SSF88659 85 159 1.23E-9 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS05180 aaffd3de216df8dba627879532e80322 182 Gene3D G3DSA:1.10.10.10 101 160 9.1E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05180 aaffd3de216df8dba627879532e80322 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 158 2.3E-17 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS05180 aaffd3de216df8dba627879532e80322 182 Gene3D G3DSA:1.10.1740.10 17 100 3.3E-13 T 22-04-2016 TOLA_RS08950 4f246c5a6b2f26cd9c30b1bd1e2fea13 267 PANTHER PTHR10953 3 253 2.7E-81 T 22-04-2016 TOLA_RS08950 4f246c5a6b2f26cd9c30b1bd1e2fea13 267 Gene3D G3DSA:3.40.50.720 3 253 2.0E-71 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS08950 4f246c5a6b2f26cd9c30b1bd1e2fea13 267 SUPERFAMILY SSF69572 3 253 9.29E-81 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TOLA_RS08950 4f246c5a6b2f26cd9c30b1bd1e2fea13 267 Pfam PF00899 ThiF family 12 249 3.7E-60 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TOLA_RS08950 4f246c5a6b2f26cd9c30b1bd1e2fea13 267 PANTHER PTHR10953:SF158 3 253 2.7E-81 T 22-04-2016 TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 SMART SM00065 72 226 0.0015 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 Pfam PF13185 GAF domain 73 217 8.8E-10 T 22-04-2016 IPR003018 GAF domain GO:0005515 TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 PANTHER PTHR10799 1 20 4.1E-28 T 22-04-2016 TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 PANTHER PTHR10799 276 405 4.1E-28 T 22-04-2016 TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 SMART SM00267 232 406 5.5E-49 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 SUPERFAMILY SSF55781 53 241 3.49E-22 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 240 405 2.1E-48 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 Gene3D G3DSA:3.30.450.40 52 232 1.3E-22 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 Pfam PF00990 Diguanylate cyclase, GGDEF domain 244 402 4.2E-39 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 PANTHER PTHR10799:SF750 1 20 4.1E-28 T 22-04-2016 TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 PANTHER PTHR10799:SF750 276 405 4.1E-28 T 22-04-2016 TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 SUPERFAMILY SSF55073 248 405 5.76E-43 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS06085 95f10c8cd820e63076ed3451b6d445d5 406 Gene3D G3DSA:3.30.70.270 245 405 1.5E-47 T 22-04-2016 TOLA_RS07315 9a703b34a9daf6dda1e0aac32b18568c 225 SUPERFAMILY SSF141488 146 222 1.57E-6 T 22-04-2016 IPR018660 C-type lysozyme, inhibitor TOLA_RS10325 3ea2c5629dbabd9731722eb69a33b2f1 348 PANTHER PTHR30307 2 348 4.3E-181 T 22-04-2016 TOLA_RS10325 3ea2c5629dbabd9731722eb69a33b2f1 348 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 344 47.448 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS10325 3ea2c5629dbabd9731722eb69a33b2f1 348 Gene3D G3DSA:3.40.1780.10 1 62 3.0E-101 T 22-04-2016 TOLA_RS10325 3ea2c5629dbabd9731722eb69a33b2f1 348 Gene3D G3DSA:3.40.1780.10 177 344 3.0E-101 T 22-04-2016 TOLA_RS10325 3ea2c5629dbabd9731722eb69a33b2f1 348 PANTHER PTHR30307:SF0 2 348 4.3E-181 T 22-04-2016 TOLA_RS10325 3ea2c5629dbabd9731722eb69a33b2f1 348 SUPERFAMILY SSF111337 1 343 2.88E-138 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS10325 3ea2c5629dbabd9731722eb69a33b2f1 348 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 344 3.4E-151 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS10325 3ea2c5629dbabd9731722eb69a33b2f1 348 Pfam PF02547 Queuosine biosynthesis protein 3 343 3.0E-134 T 22-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS10325 3ea2c5629dbabd9731722eb69a33b2f1 348 Gene3D G3DSA:2.40.10.240 64 140 2.0E-17 T 22-04-2016 TOLA_RS05315 a21112d747ef89bd959a999b76a3ac85 512 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 497 1.9E-123 T 22-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 TOLA_RS05315 a21112d747ef89bd959a999b76a3ac85 512 Gene3D G3DSA:1.20.1250.20 272 432 1.3E-16 T 22-04-2016 TOLA_RS05315 a21112d747ef89bd959a999b76a3ac85 512 Gene3D G3DSA:1.20.1250.20 481 505 1.3E-16 T 22-04-2016 TOLA_RS05315 a21112d747ef89bd959a999b76a3ac85 512 Pfam PF07690 Major Facilitator Superfamily 25 418 6.4E-51 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS05315 a21112d747ef89bd959a999b76a3ac85 512 PANTHER PTHR23501 10 502 2.1E-234 T 22-04-2016 TOLA_RS05315 a21112d747ef89bd959a999b76a3ac85 512 Gene3D G3DSA:1.20.1250.20 22 198 3.9E-30 T 22-04-2016 TOLA_RS05315 a21112d747ef89bd959a999b76a3ac85 512 SUPERFAMILY SSF103473 476 506 8.5E-61 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS05315 a21112d747ef89bd959a999b76a3ac85 512 SUPERFAMILY SSF103473 10 202 8.5E-61 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS05315 a21112d747ef89bd959a999b76a3ac85 512 SUPERFAMILY SSF103473 257 428 8.5E-61 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS05315 a21112d747ef89bd959a999b76a3ac85 512 PANTHER PTHR23501:SF52 10 502 2.1E-234 T 22-04-2016 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 252.498 T 22-04-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 SUPERFAMILY SSF52540 90 371 4.31E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 2.3E-32 T 22-04-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 PANTHER PTHR15184:SF34 54 141 1.8E-200 T 22-04-2016 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 PANTHER PTHR15184:SF34 160 416 1.8E-200 T 22-04-2016 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 Gene3D G3DSA:2.40.50.140 49 117 1.3E-36 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 Gene3D G3DSA:3.40.50.300 132 418 1.8E-106 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 2.5E-14 T 22-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 SMART SM00959 5 47 8.5E-15 T 22-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 Gene3D G3DSA:1.10.720.10 1 47 3.3E-19 T 22-04-2016 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 SUPERFAMILY SSF68912 1 46 1.33E-10 T 22-04-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 3.3E-23 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 SUPERFAMILY SSF50249 48 125 1.03E-29 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 9.4E-221 T 22-04-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 SMART SM00357 52 118 5.0E-19 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 PANTHER PTHR15184 54 141 1.8E-200 T 22-04-2016 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 PANTHER PTHR15184 160 416 1.8E-200 T 22-04-2016 TOLA_RS13535 62ca726e69c31a834eae58519b75722d 421 SMART SM00382 170 356 4.9E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS02715 84d5ba8497a060034840bc00bb2351df 392 PANTHER PTHR30474 3 382 4.0E-158 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 TOLA_RS02715 84d5ba8497a060034840bc00bb2351df 392 PANTHER PTHR30474:SF2 3 382 4.0E-158 T 22-04-2016 TOLA_RS02715 84d5ba8497a060034840bc00bb2351df 392 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 25 378 6.6E-122 T 22-04-2016 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 TOLA_RS02715 84d5ba8497a060034840bc00bb2351df 392 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 23 385 39.19 T 22-04-2016 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 TOLA_RS02715 84d5ba8497a060034840bc00bb2351df 392 Pfam PF01098 Cell cycle protein 28 379 1.9E-110 T 22-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 TOLA_RS02715 84d5ba8497a060034840bc00bb2351df 392 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 337 361 - T 22-04-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 TOLA_RS14085 4783bbcc8f495c98ee7d8c4e4276a625 246 Gene3D G3DSA:3.60.21.10 6 238 2.4E-42 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS14085 4783bbcc8f495c98ee7d8c4e4276a625 246 SUPERFAMILY SSF56300 7 236 1.74E-37 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS14085 4783bbcc8f495c98ee7d8c4e4276a625 246 PANTHER PTHR24032 11 123 3.1E-17 T 22-04-2016 TOLA_RS14085 4783bbcc8f495c98ee7d8c4e4276a625 246 Pfam PF00149 Calcineurin-like phosphoesterase 12 205 3.5E-14 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 TOLA_RS02745 59a6b8d19832bda470babdfeb47c4aca 307 SUPERFAMILY SSF54211 134 279 2.12E-51 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS02745 59a6b8d19832bda470babdfeb47c4aca 307 Hamap MF_00388 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [lpxC]. 2 282 47.108 T 22-04-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 TOLA_RS02745 59a6b8d19832bda470babdfeb47c4aca 307 Gene3D G3DSA:3.30.230.20 3 125 2.6E-43 T 22-04-2016 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 TOLA_RS02745 59a6b8d19832bda470babdfeb47c4aca 307 PANTHER PTHR33694:SF1 1 293 7.6E-128 T 22-04-2016 TOLA_RS02745 59a6b8d19832bda470babdfeb47c4aca 307 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 294 5.2E-130 T 22-04-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 TOLA_RS02745 59a6b8d19832bda470babdfeb47c4aca 307 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 277 1.6E-106 T 22-04-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 TOLA_RS02745 59a6b8d19832bda470babdfeb47c4aca 307 Gene3D G3DSA:3.30.1700.10 129 284 4.8E-61 T 22-04-2016 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 TOLA_RS02745 59a6b8d19832bda470babdfeb47c4aca 307 SUPERFAMILY SSF54211 3 124 1.52E-40 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS02745 59a6b8d19832bda470babdfeb47c4aca 307 PANTHER PTHR33694 1 293 7.6E-128 T 22-04-2016 TOLA_RS09960 c33409915e7dfc3f6a3bbc3e7b766a77 400 PANTHER PTHR11895 20 398 2.8E-83 T 22-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TOLA_RS09960 c33409915e7dfc3f6a3bbc3e7b766a77 400 ProSitePatterns PS00571 Amidases signature. 108 139 - T 22-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TOLA_RS09960 c33409915e7dfc3f6a3bbc3e7b766a77 400 SUPERFAMILY SSF75304 22 392 8.5E-83 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TOLA_RS09960 c33409915e7dfc3f6a3bbc3e7b766a77 400 Gene3D G3DSA:3.90.1300.10 21 396 7.9E-86 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TOLA_RS09960 c33409915e7dfc3f6a3bbc3e7b766a77 400 Pfam PF01425 Amidase 264 381 1.1E-6 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TOLA_RS09960 c33409915e7dfc3f6a3bbc3e7b766a77 400 Pfam PF01425 Amidase 21 197 1.5E-48 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TOLA_RS01950 e8921a4f7be604c09ebcc7489829c442 196 Gene3D G3DSA:3.90.79.10 14 188 1.3E-39 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS01950 e8921a4f7be604c09ebcc7489829c442 196 Pfam PF00293 NUDIX domain 52 161 1.3E-13 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TOLA_RS01950 e8921a4f7be604c09ebcc7489829c442 196 SUPERFAMILY SSF55811 14 185 1.03E-37 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS01950 e8921a4f7be604c09ebcc7489829c442 196 ProSitePatterns PS00893 Nudix box signature. 86 107 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TOLA_RS01950 e8921a4f7be604c09ebcc7489829c442 196 PANTHER PTHR11839 9 182 1.3E-81 T 22-04-2016 TOLA_RS01950 e8921a4f7be604c09ebcc7489829c442 196 PANTHER PTHR11839:SF12 9 182 1.3E-81 T 22-04-2016 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 PANTHER PTHR12128 1 292 3.5E-127 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 1.9E-32 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 1.9E-32 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 1.9E-32 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 1.9E-32 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 SMART SM01130 1 290 1.1E-127 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 288 62.076 T 22-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 SUPERFAMILY SSF51569 1 291 1.67E-93 T 22-04-2016 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 PIRSF PIRSF001365 1 291 1.5E-80 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 PANTHER PTHR12128:SF34 1 292 3.5E-127 T 22-04-2016 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 22-04-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 Gene3D G3DSA:3.20.20.70 1 292 1.1E-104 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 286 9.3E-107 T 22-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 22-04-2016 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS05785 c614a022f6fa2e5a73cf68d1d9f8be41 292 Pfam PF00701 Dihydrodipicolinate synthetase family 2 286 5.9E-97 T 22-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 TOLA_RS04165 878ec79f21df75175e241143fc353811 362 Gene3D G3DSA:3.40.50.2300 76 180 6.5E-27 T 22-04-2016 TOLA_RS04165 878ec79f21df75175e241143fc353811 362 Gene3D G3DSA:3.40.50.2300 181 344 1.0E-31 T 22-04-2016 TOLA_RS04165 878ec79f21df75175e241143fc353811 362 Pfam PF00356 Bacterial regulatory proteins, lacI family 18 66 5.3E-16 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS04165 878ec79f21df75175e241143fc353811 362 SMART SM00354 16 89 7.6E-27 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS04165 878ec79f21df75175e241143fc353811 362 PANTHER PTHR30146:SF25 16 342 3.3E-72 T 22-04-2016 TOLA_RS04165 878ec79f21df75175e241143fc353811 362 SUPERFAMILY SSF53822 76 331 8.64E-43 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS04165 878ec79f21df75175e241143fc353811 362 Pfam PF13377 Periplasmic binding protein-like domain 196 344 1.2E-12 T 22-04-2016 TOLA_RS04165 878ec79f21df75175e241143fc353811 362 PANTHER PTHR30146 16 342 3.3E-72 T 22-04-2016 TOLA_RS04165 878ec79f21df75175e241143fc353811 362 SUPERFAMILY SSF47413 17 74 2.7E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS04165 878ec79f21df75175e241143fc353811 362 Gene3D G3DSA:1.10.260.40 17 75 2.5E-24 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 Gene3D G3DSA:3.30.450.20 189 312 7.7E-19 T 22-04-2016 TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 PANTHER PTHR10799 356 598 1.7E-88 T 22-04-2016 TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 PANTHER PTHR10799 46 194 1.7E-88 T 22-04-2016 TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 SMART SM00052 499 745 1.7E-119 T 22-04-2016 IPR001633 EAL domain TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 PANTHER PTHR10799:SF774 356 598 1.7E-88 T 22-04-2016 TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 PANTHER PTHR10799:SF774 46 194 1.7E-88 T 22-04-2016 TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 195 317 2.4E-9 T 22-04-2016 IPR000014 PAS domain TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 Gene3D G3DSA:3.30.70.270 325 495 6.5E-58 T 22-04-2016 TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 Pfam PF08448 PAS fold 206 313 1.7E-7 T 22-04-2016 IPR013656 PAS fold-4 TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 Pfam PF00990 Diguanylate cyclase, GGDEF domain 323 485 4.4E-49 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 SUPERFAMILY SSF55785 184 310 2.27E-14 T 22-04-2016 IPR000014 PAS domain TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 Pfam PF07694 5TMR of 5TMR-LYT 26 183 2.0E-30 T 22-04-2016 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 SMART SM00267 312 489 7.2E-59 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 Pfam PF00563 EAL domain 505 740 1.8E-76 T 22-04-2016 IPR001633 EAL domain TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 Gene3D G3DSA:3.20.20.450 502 746 3.5E-100 T 22-04-2016 IPR001633 EAL domain TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 SUPERFAMILY SSF141868 504 748 6.02E-92 T 22-04-2016 IPR001633 EAL domain TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 320 488 3.2E-44 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS15970 93bf7339db4521b60c8fc408532a6420 753 SUPERFAMILY SSF55073 328 491 1.69E-49 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS16410 a5d0b7efb1d6388b9787983a07a99ed7 94 SMART SM00360 1 73 1.6E-22 T 22-04-2016 IPR000504 RNA recognition motif domain GO:0003676 TOLA_RS16410 a5d0b7efb1d6388b9787983a07a99ed7 94 PANTHER PTHR24012 1 93 2.8E-22 T 22-04-2016 TOLA_RS16410 a5d0b7efb1d6388b9787983a07a99ed7 94 Pfam PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2 71 1.4E-19 T 22-04-2016 IPR000504 RNA recognition motif domain GO:0003676 TOLA_RS16410 a5d0b7efb1d6388b9787983a07a99ed7 94 Gene3D G3DSA:3.30.70.330 1 80 6.5E-25 T 22-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 TOLA_RS16410 a5d0b7efb1d6388b9787983a07a99ed7 94 SUPERFAMILY SSF54928 1 80 1.11E-24 T 22-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 TOLA_RS09195 85c884fc4ab3a25e4873cb65658de763 219 Pfam PF01936 NYN domain 17 130 7.5E-8 T 22-04-2016 IPR021139 NYN domain, limkain-b1-type TOLA_RS09195 85c884fc4ab3a25e4873cb65658de763 219 Gene3D G3DSA:3.40.50.1010 42 133 2.5E-4 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 SUPERFAMILY SSF56784 4 223 1.4E-52 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 49 196 7.0E-26 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 190 4.0E-16 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 Gene3D G3DSA:1.10.150.240 16 89 4.1E-20 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 59 196 1.3E-12 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 PANTHER PTHR12725:SF57 1 223 4.4E-57 T 22-04-2016 TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 PANTHER PTHR12725 1 223 4.4E-57 T 22-04-2016 TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 4 223 1.7E-76 T 22-04-2016 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 185 198 1.1E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 107 120 1.1E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 138 154 1.1E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 1.1E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS05460 e098ac2979e33b1060685ef3f4fb497f 227 Gene3D G3DSA:3.40.50.1000 90 223 1.1E-45 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS04175 2d90e3632ecbc870a9cc2b8fe566e91b 456 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 28 111 2.1E-21 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS04175 2d90e3632ecbc870a9cc2b8fe566e91b 456 Pfam PF02378 Phosphotransferase system, EIIC 110 395 5.3E-45 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS04175 2d90e3632ecbc870a9cc2b8fe566e91b 456 Pfam PF00367 phosphotransferase system, EIIB 9 41 4.2E-14 T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS04175 2d90e3632ecbc870a9cc2b8fe566e91b 456 PANTHER PTHR30175:SF7 1 456 8.2E-190 T 22-04-2016 TOLA_RS04175 2d90e3632ecbc870a9cc2b8fe566e91b 456 PANTHER PTHR30175 1 456 8.2E-190 T 22-04-2016 TOLA_RS04175 2d90e3632ecbc870a9cc2b8fe566e91b 456 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 153 437 7.7E-88 T 22-04-2016 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 TOLA_RS04175 2d90e3632ecbc870a9cc2b8fe566e91b 456 Gene3D G3DSA:3.30.1360.60 2 82 6.7E-26 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS04175 2d90e3632ecbc870a9cc2b8fe566e91b 456 SUPERFAMILY SSF55604 6 81 3.4E-20 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS04175 2d90e3632ecbc870a9cc2b8fe566e91b 456 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS04175 2d90e3632ecbc870a9cc2b8fe566e91b 456 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 4 448 2.5E-189 T 22-04-2016 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 TOLA_RS06055 b721a43d3cd902a196eb686cad29a8d4 1030 Pfam PF04851 Type III restriction enzyme, res subunit 251 422 3.5E-17 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TOLA_RS06055 b721a43d3cd902a196eb686cad29a8d4 1030 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 18 702 3.5E-164 T 22-04-2016 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 TOLA_RS06055 b721a43d3cd902a196eb686cad29a8d4 1030 SUPERFAMILY SSF52540 206 454 3.32E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06055 b721a43d3cd902a196eb686cad29a8d4 1030 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 7 197 3.8E-33 T 22-04-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 TOLA_RS06055 b721a43d3cd902a196eb686cad29a8d4 1030 SMART SM00487 247 459 2.0E-8 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS06055 b721a43d3cd902a196eb686cad29a8d4 1030 PANTHER PTHR30195:SF15 52 571 2.3E-103 T 22-04-2016 TOLA_RS06055 b721a43d3cd902a196eb686cad29a8d4 1030 PANTHER PTHR30195:SF15 591 937 2.3E-103 T 22-04-2016 TOLA_RS06055 b721a43d3cd902a196eb686cad29a8d4 1030 PANTHER PTHR30195 52 571 2.3E-103 T 22-04-2016 TOLA_RS06055 b721a43d3cd902a196eb686cad29a8d4 1030 PANTHER PTHR30195 591 937 2.3E-103 T 22-04-2016 TOLA_RS06055 b721a43d3cd902a196eb686cad29a8d4 1030 Gene3D G3DSA:3.40.50.300 255 436 4.4E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00270 230210e12ce3395d4c25ab9c7869bd34 341 PANTHER PTHR10584:SF166 8 332 1.5E-45 T 22-04-2016 TOLA_RS00270 230210e12ce3395d4c25ab9c7869bd34 341 SUPERFAMILY SSF53613 7 319 5.3E-51 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS00270 230210e12ce3395d4c25ab9c7869bd34 341 PANTHER PTHR10584 8 332 1.5E-45 T 22-04-2016 TOLA_RS00270 230210e12ce3395d4c25ab9c7869bd34 341 Gene3D G3DSA:3.40.1190.20 7 335 5.0E-57 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS00270 230210e12ce3395d4c25ab9c7869bd34 341 Pfam PF00294 pfkB family carbohydrate kinase 15 320 1.4E-38 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 PIRSF PIRSF000732 1 572 1.4E-221 T 22-04-2016 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 22-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 2 566 1.6E-247 T 22-04-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 SUPERFAMILY SSF51621 249 549 3.4E-112 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 PANTHER PTHR22931 66 550 2.9E-213 T 22-04-2016 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 Pfam PF05524 PEP-utilising enzyme, N-terminal 4 126 5.2E-31 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 250 540 7.2E-127 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 Gene3D G3DSA:3.50.30.10 134 255 8.5E-41 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 Gene3D G3DSA:1.10.274.10 24 133 6.1E-38 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 4.6E-30 T 22-04-2016 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 4.6E-30 T 22-04-2016 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 4.6E-30 T 22-04-2016 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 4.6E-30 T 22-04-2016 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 Gene3D G3DSA:3.20.20.60 256 569 5.1E-117 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 SUPERFAMILY SSF52009 125 246 1.05E-36 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 22-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 SUPERFAMILY SSF47831 25 143 1.44E-34 T 22-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 TOLA_RS03230 ff708d9d84e75aaa66f518c8577cdc4d 572 Pfam PF00391 PEP-utilising enzyme, mobile domain 152 222 2.3E-22 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 PANTHER PTHR30081 1 173 3.2E-213 T 22-04-2016 TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 PANTHER PTHR30081 315 615 3.2E-213 T 22-04-2016 TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 616 46.448 T 22-04-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 PANTHER PTHR30081 226 284 3.2E-213 T 22-04-2016 TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 SUPERFAMILY SSF82866 412 608 4.05E-42 T 22-04-2016 TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 Pfam PF07549 SecD/SecF GG Motif 115 140 1.5E-7 T 22-04-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 347 596 2.9E-78 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 123 603 3.2E-147 T 22-04-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 PANTHER PTHR30081:SF1 315 615 3.2E-213 T 22-04-2016 TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 PANTHER PTHR30081:SF1 226 284 3.2E-213 T 22-04-2016 TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 PANTHER PTHR30081:SF1 1 173 3.2E-213 T 22-04-2016 TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 Pfam PF02355 Protein export membrane protein 435 600 2.2E-19 T 22-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 Gene3D G3DSA:1.20.1640.10 412 608 5.8E-24 T 22-04-2016 TOLA_RS10310 61c70a89b6cd766b531b351708415882 617 Pfam PF13721 SecD export protein N-terminal TM region 2 103 1.9E-36 T 22-04-2016 IPR027398 SecD export protein N-terminal TM domain TOLA_RS12365 2e7e0d88a7b4235bc90b74cb68928748 242 Gene3D G3DSA:3.40.30.10 152 198 9.7E-4 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS12365 2e7e0d88a7b4235bc90b74cb68928748 242 TIGRFAM TIGR03759 conj_TIGR03759: integrating conjugative element protein, PFL_4693 family 43 239 1.0E-84 T 22-04-2016 IPR022293 Integrating conjugative element protein, PFL4693 TOLA_RS13480 9e854477f1c67f10b7a9e105789c962d 102 PANTHER PTHR11434 5 102 5.3E-57 T 22-04-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 TOLA_RS13480 9e854477f1c67f10b7a9e105789c962d 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 10 98 3.0E-22 T 22-04-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 TOLA_RS13480 9e854477f1c67f10b7a9e105789c962d 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 4 102 18.649 T 22-04-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 TOLA_RS13480 9e854477f1c67f10b7a9e105789c962d 102 PANTHER PTHR11434:SF4 5 102 5.3E-57 T 22-04-2016 TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 SMART SM00052 841 1087 4.3E-122 T 22-04-2016 IPR001633 EAL domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 SMART SM00086 494 536 2.1E-4 T 22-04-2016 IPR001610 PAC motif TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 SMART SM00086 616 658 0.0057 T 22-04-2016 IPR001610 PAC motif TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 SMART SM00091 544 610 7.7E-9 T 22-04-2016 IPR000014 PAS domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 SMART SM00091 420 487 1.0 T 22-04-2016 IPR000014 PAS domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 Gene3D G3DSA:3.30.70.270 670 837 1.7E-57 T 22-04-2016 TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 SUPERFAMILY SSF55785 552 655 2.27E-25 T 22-04-2016 IPR000014 PAS domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 Gene3D G3DSA:3.20.20.450 844 1095 5.6E-105 T 22-04-2016 IPR001633 EAL domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 PANTHER PTHR10799:SF774 6 66 4.9E-86 T 22-04-2016 TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 PANTHER PTHR10799:SF774 702 941 4.9E-86 T 22-04-2016 TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 PANTHER PTHR10799:SF774 348 525 4.9E-86 T 22-04-2016 TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 SMART SM00267 658 831 3.0E-65 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 SUPERFAMILY SSF55073 674 833 2.2E-48 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 PANTHER PTHR10799 6 66 4.9E-86 T 22-04-2016 TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 PANTHER PTHR10799 702 941 4.9E-86 T 22-04-2016 TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 PANTHER PTHR10799 348 525 4.9E-86 T 22-04-2016 TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 SUPERFAMILY SSF55785 436 545 2.79E-14 T 22-04-2016 IPR000014 PAS domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 665 829 7.1E-47 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 Gene3D G3DSA:3.30.450.20 536 651 2.1E-25 T 22-04-2016 TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 548 665 4.3E-17 T 22-04-2016 IPR000014 PAS domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 421 541 1.6E-15 T 22-04-2016 IPR000014 PAS domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 Pfam PF00563 EAL domain 848 1082 1.7E-80 T 22-04-2016 IPR001633 EAL domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 Gene3D G3DSA:3.30.450.20 432 535 4.5E-13 T 22-04-2016 TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 Pfam PF00990 Diguanylate cyclase, GGDEF domain 669 826 1.5E-49 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 Pfam PF13426 PAS domain 555 657 3.0E-14 T 22-04-2016 IPR000014 PAS domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 Pfam PF13426 PAS domain 439 534 1.2E-8 T 22-04-2016 IPR000014 PAS domain TOLA_RS02485 516842d214f53e181f244188bfebbde9 1101 SUPERFAMILY SSF141868 848 1094 7.72E-94 T 22-04-2016 IPR001633 EAL domain TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 Gene3D G3DSA:1.10.10.60 252 299 4.2E-18 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 SUPERFAMILY SSF46689 251 300 9.86E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 PANTHER PTHR11019 25 298 2.3E-106 T 22-04-2016 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 PANTHER PTHR11019:SF123 25 298 2.3E-106 T 22-04-2016 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 Pfam PF02311 AraC-like ligand binding domain 60 177 4.8E-21 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 Pfam PF12833 Helix-turn-helix domain 220 298 1.7E-20 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 SUPERFAMILY SSF46689 197 247 9.86E-7 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 SUPERFAMILY SSF51215 27 185 1.02E-32 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 251 293 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 Gene3D G3DSA:2.60.120.280 28 187 2.1E-41 T 22-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 266 281 6.4E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 281 297 6.4E-7 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 Gene3D G3DSA:1.10.10.60 195 251 6.8E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS10950 8d9f7775fb81f0c4c278d0c2278e9de8 303 SMART SM00342 214 297 1.2E-33 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS16005 75f36d10aca9dbd1dcfe37ae050e3895 309 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 10 92 1.3E-20 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TOLA_RS16005 75f36d10aca9dbd1dcfe37ae050e3895 309 SUPERFAMILY SSF56349 5 292 1.65E-54 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TOLA_RS16005 75f36d10aca9dbd1dcfe37ae050e3895 309 Pfam PF00589 Phage integrase family 115 284 2.9E-49 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS16005 75f36d10aca9dbd1dcfe37ae050e3895 309 Gene3D G3DSA:1.10.443.10 116 291 2.1E-51 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS16005 75f36d10aca9dbd1dcfe37ae050e3895 309 PANTHER PTHR30349:SF17 1 302 3.3E-136 T 22-04-2016 TOLA_RS16005 75f36d10aca9dbd1dcfe37ae050e3895 309 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 298 35.958 T 22-04-2016 IPR023009 Tyrosine recombinase XerC/XerD TOLA_RS16005 75f36d10aca9dbd1dcfe37ae050e3895 309 PANTHER PTHR30349 1 302 3.3E-136 T 22-04-2016 TOLA_RS16005 75f36d10aca9dbd1dcfe37ae050e3895 309 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 11 300 2.1E-108 T 22-04-2016 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 TOLA_RS16005 75f36d10aca9dbd1dcfe37ae050e3895 309 Gene3D G3DSA:1.10.150.130 7 103 8.3E-26 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal TOLA_RS13185 1c119916325612fcac61231fd36cf8a8 355 SUPERFAMILY SSF51726 3 353 2.35E-119 T 22-04-2016 TOLA_RS13185 1c119916325612fcac61231fd36cf8a8 355 Gene3D G3DSA:3.20.20.210 5 353 7.9E-153 T 22-04-2016 TOLA_RS13185 1c119916325612fcac61231fd36cf8a8 355 PANTHER PTHR21091:SF2 1 349 3.2E-152 T 22-04-2016 TOLA_RS13185 1c119916325612fcac61231fd36cf8a8 355 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 349 50.618 T 22-04-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 TOLA_RS13185 1c119916325612fcac61231fd36cf8a8 355 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 142 158 - T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 TOLA_RS13185 1c119916325612fcac61231fd36cf8a8 355 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 347 4.1E-137 T 22-04-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 TOLA_RS13185 1c119916325612fcac61231fd36cf8a8 355 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 TOLA_RS13185 1c119916325612fcac61231fd36cf8a8 355 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 348 9.1E-141 T 22-04-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 TOLA_RS13185 1c119916325612fcac61231fd36cf8a8 355 PANTHER PTHR21091 1 349 3.2E-152 T 22-04-2016 TOLA_RS08105 f08df260b2fb48eda34afcec6b96c649 692 Gene3D G3DSA:3.40.50.300 242 429 4.9E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08105 f08df260b2fb48eda34afcec6b96c649 692 SMART SM00487 242 447 1.1E-15 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS08105 f08df260b2fb48eda34afcec6b96c649 692 PANTHER PTHR11274 492 633 2.1E-36 T 22-04-2016 TOLA_RS08105 f08df260b2fb48eda34afcec6b96c649 692 PANTHER PTHR11274 240 469 2.1E-36 T 22-04-2016 TOLA_RS08105 f08df260b2fb48eda34afcec6b96c649 692 Pfam PF13091 PLD-like domain 31 196 1.1E-7 T 22-04-2016 IPR025202 Phospholipase D-like domain TOLA_RS08105 f08df260b2fb48eda34afcec6b96c649 692 SMART SM00490 539 621 3.3E-12 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS08105 f08df260b2fb48eda34afcec6b96c649 692 Gene3D G3DSA:3.40.50.300 503 631 2.3E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08105 f08df260b2fb48eda34afcec6b96c649 692 Pfam PF04851 Type III restriction enzyme, res subunit 245 412 1.1E-17 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TOLA_RS08105 f08df260b2fb48eda34afcec6b96c649 692 Pfam PF00271 Helicase conserved C-terminal domain 507 620 1.9E-13 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS08105 f08df260b2fb48eda34afcec6b96c649 692 SUPERFAMILY SSF52540 488 629 4.49E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08105 f08df260b2fb48eda34afcec6b96c649 692 SUPERFAMILY SSF52540 257 413 4.49E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01985 947d1d294775e13e86469b45df71a2cf 617 SUPERFAMILY SSF56935 29 615 2.01E-115 T 22-04-2016 TOLA_RS01985 947d1d294775e13e86469b45df71a2cf 617 PANTHER PTHR30069:SF10 29 593 6.2E-123 T 22-04-2016 TOLA_RS01985 947d1d294775e13e86469b45df71a2cf 617 Pfam PF00593 TonB dependent receptor 397 616 7.0E-32 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 TOLA_RS01985 947d1d294775e13e86469b45df71a2cf 617 Pfam PF07715 TonB-dependent Receptor Plug Domain 42 146 1.1E-27 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 TOLA_RS01985 947d1d294775e13e86469b45df71a2cf 617 Gene3D G3DSA:2.170.130.10 29 150 1.9E-37 T 22-04-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 TOLA_RS01985 947d1d294775e13e86469b45df71a2cf 617 Gene3D G3DSA:2.40.170.20 151 616 6.5E-83 T 22-04-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 TOLA_RS01985 947d1d294775e13e86469b45df71a2cf 617 Hamap MF_01531 Vitamin B12 transporter BtuB [btuB]. 1 617 34.292 T 22-04-2016 IPR010101 TonB-dependent vitamin B12 transporter BtuB GO:0004872|GO:0015235|GO:0015889|GO:0016020 TOLA_RS01985 947d1d294775e13e86469b45df71a2cf 617 PANTHER PTHR30069 29 593 6.2E-123 T 22-04-2016 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 26 702 1.6E-260 T 22-04-2016 IPR004811 RelA/SpoT family GO:0015969 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 Gene3D G3DSA:3.10.20.30 388 449 6.6E-22 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 SMART SM00471 41 153 1.8E-8 T 22-04-2016 IPR003607 HD/PDEase domain TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 Pfam PF04607 Region found in RelA / SpoT proteins 235 345 1.8E-35 T 22-04-2016 IPR007685 RelA/SpoT GO:0015969 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 Pfam PF02824 TGS domain 389 448 4.7E-20 T 22-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 SUPERFAMILY SSF109604 3 190 4.71E-71 T 22-04-2016 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 SUPERFAMILY SSF55021 629 707 2.65E-9 T 22-04-2016 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 Pfam PF13328 HD domain 26 175 1.3E-51 T 22-04-2016 IPR003607 HD/PDEase domain TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 SUPERFAMILY SSF81301 181 393 8.83E-62 T 22-04-2016 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 Pfam PF13291 ACT domain 626 703 7.1E-17 T 22-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 PANTHER PTHR21262 3 706 0.0 T 22-04-2016 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 SMART SM00954 235 345 2.9E-60 T 22-04-2016 IPR007685 RelA/SpoT GO:0015969 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 SUPERFAMILY SSF81271 376 448 9.59E-21 T 22-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 PANTHER PTHR21262:SF0 3 706 0.0 T 22-04-2016 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 Gene3D G3DSA:3.30.460.10 178 324 1.9E-47 T 22-04-2016 TOLA_RS00950 767bd08ce43dccaf00ad84ed8503832e 715 Gene3D G3DSA:3.30.70.260 628 701 4.3E-9 T 22-04-2016 TOLA_RS00300 5b6aedc00693b3410b4a47fb3528c149 507 Gene3D G3DSA:3.40.50.300 276 492 2.4E-47 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00300 5b6aedc00693b3410b4a47fb3528c149 507 Gene3D G3DSA:3.40.50.300 3 238 5.9E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00300 5b6aedc00693b3410b4a47fb3528c149 507 SUPERFAMILY SSF52540 276 486 1.87E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00300 5b6aedc00693b3410b4a47fb3528c149 507 PANTHER PTHR24220 9 381 5.4E-184 T 22-04-2016 TOLA_RS00300 5b6aedc00693b3410b4a47fb3528c149 507 Pfam PF00005 ABC transporter 276 426 8.7E-21 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS00300 5b6aedc00693b3410b4a47fb3528c149 507 Pfam PF00005 ABC transporter 23 172 2.5E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS00300 5b6aedc00693b3410b4a47fb3528c149 507 ProSitePatterns PS00211 ABC transporters family signature. 399 413 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS00300 5b6aedc00693b3410b4a47fb3528c149 507 SUPERFAMILY SSF52540 6 230 1.81E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00300 5b6aedc00693b3410b4a47fb3528c149 507 SMART SM00382 32 219 1.4E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS00300 5b6aedc00693b3410b4a47fb3528c149 507 SMART SM00382 281 475 1.9E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS00300 5b6aedc00693b3410b4a47fb3528c149 507 PANTHER PTHR24220:SF416 9 381 5.4E-184 T 22-04-2016 TOLA_RS16070 418bbc3dbd648a316e2624ad564cf008 140 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 90 134 1.5E-10 T 22-04-2016 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain TOLA_RS16070 418bbc3dbd648a316e2624ad564cf008 140 PANTHER PTHR13822 5 140 3.8E-38 T 22-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16070 418bbc3dbd648a316e2624ad564cf008 140 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 5 134 7.0E-41 T 22-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16070 418bbc3dbd648a316e2624ad564cf008 140 SUPERFAMILY SSF51344 5 87 1.44E-23 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16070 418bbc3dbd648a316e2624ad564cf008 140 Gene3D G3DSA:2.60.15.10 5 92 7.3E-29 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16070 418bbc3dbd648a316e2624ad564cf008 140 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 85 7.7E-28 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16070 418bbc3dbd648a316e2624ad564cf008 140 SUPERFAMILY SSF46604 90 138 1.62E-13 T 22-04-2016 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain TOLA_RS16070 418bbc3dbd648a316e2624ad564cf008 140 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 4 132 20.072 T 22-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16070 418bbc3dbd648a316e2624ad564cf008 140 Gene3D G3DSA:1.20.5.440 93 134 8.0E-20 T 22-04-2016 TOLA_RS16070 418bbc3dbd648a316e2624ad564cf008 140 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 11 91 2.0E-27 T 22-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS02195 ac52f6fff0e830f085a89a2826454f4b 299 PIRSF PIRSF005261 1 287 4.4E-77 T 22-04-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 TOLA_RS02195 ac52f6fff0e830f085a89a2826454f4b 299 PANTHER PTHR30111:SF1 4 291 6.4E-80 T 22-04-2016 TOLA_RS02195 ac52f6fff0e830f085a89a2826454f4b 299 Gene3D G3DSA:3.55.30.10 4 177 2.7E-65 T 22-04-2016 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 TOLA_RS02195 ac52f6fff0e830f085a89a2826454f4b 299 SUPERFAMILY SSF64397 6 235 8.89E-77 T 22-04-2016 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 TOLA_RS02195 ac52f6fff0e830f085a89a2826454f4b 299 SUPERFAMILY SSF118352 228 286 1.7E-17 T 22-04-2016 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 TOLA_RS02195 ac52f6fff0e830f085a89a2826454f4b 299 PANTHER PTHR30111 4 291 6.4E-80 T 22-04-2016 TOLA_RS02195 ac52f6fff0e830f085a89a2826454f4b 299 Pfam PF01430 Hsp33 protein 6 276 7.1E-87 T 22-04-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 TOLA_RS02195 ac52f6fff0e830f085a89a2826454f4b 299 Hamap MF_00117 33 kDa chaperonin [hslO]. 5 287 32.192 T 22-04-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 TOLA_RS02195 ac52f6fff0e830f085a89a2826454f4b 299 Gene3D G3DSA:1.10.287.480 182 228 8.2E-25 T 22-04-2016 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain TOLA_RS02195 ac52f6fff0e830f085a89a2826454f4b 299 Gene3D G3DSA:3.90.1280.10 229 286 4.4E-21 T 22-04-2016 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 TOLA_RS06615 b6e81e8235c8e0c707987b8417bdcfe6 115 Pfam PF07883 Cupin domain 41 96 1.3E-9 T 22-04-2016 IPR013096 Cupin 2, conserved barrel TOLA_RS06615 b6e81e8235c8e0c707987b8417bdcfe6 115 Gene3D G3DSA:2.60.120.10 17 99 3.9E-22 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS06615 b6e81e8235c8e0c707987b8417bdcfe6 115 SUPERFAMILY SSF51182 22 98 2.57E-16 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS15670 a000d071190d2debeab81ce02c8f2a64 305 PIRSF PIRSF002849 2 304 4.2E-115 T 22-04-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted TOLA_RS15670 a000d071190d2debeab81ce02c8f2a64 305 SUPERFAMILY SSF52540 6 278 2.11E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15670 a000d071190d2debeab81ce02c8f2a64 305 PANTHER PTHR11603 5 281 1.1E-142 T 22-04-2016 TOLA_RS15670 a000d071190d2debeab81ce02c8f2a64 305 Gene3D G3DSA:1.10.8.300 196 290 4.0E-24 T 22-04-2016 TOLA_RS15670 a000d071190d2debeab81ce02c8f2a64 305 SMART SM00382 36 176 7.4E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS15670 a000d071190d2debeab81ce02c8f2a64 305 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 39 168 7.2E-61 T 22-04-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TOLA_RS15670 a000d071190d2debeab81ce02c8f2a64 305 PANTHER PTHR11603:SF155 5 281 1.1E-142 T 22-04-2016 TOLA_RS15670 a000d071190d2debeab81ce02c8f2a64 305 Gene3D G3DSA:3.40.50.300 22 184 2.5E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05135 fabeeaa40ad8bf9912057cef01417d9a 212 Pfam PF16925 Bacterial transcriptional repressor C-terminal 97 210 1.4E-48 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TOLA_RS05135 fabeeaa40ad8bf9912057cef01417d9a 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 70 6.1E-10 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS05135 fabeeaa40ad8bf9912057cef01417d9a 212 Gene3D G3DSA:1.10.357.10 17 203 7.9E-39 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 TOLA_RS05135 fabeeaa40ad8bf9912057cef01417d9a 212 PANTHER PTHR30055:SF20 10 202 8.0E-41 T 22-04-2016 TOLA_RS05135 fabeeaa40ad8bf9912057cef01417d9a 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 6.4E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS05135 fabeeaa40ad8bf9912057cef01417d9a 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 6.4E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS05135 fabeeaa40ad8bf9912057cef01417d9a 212 SUPERFAMILY SSF48498 98 203 1.63E-23 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TOLA_RS05135 fabeeaa40ad8bf9912057cef01417d9a 212 PANTHER PTHR30055 10 202 8.0E-41 T 22-04-2016 TOLA_RS05135 fabeeaa40ad8bf9912057cef01417d9a 212 SUPERFAMILY SSF46689 18 93 1.49E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS04170 6dc50518ed4f7b51489ae2836749c756 471 SUPERFAMILY SSF49899 337 468 6.41E-18 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain TOLA_RS04170 6dc50518ed4f7b51489ae2836749c756 471 Gene3D G3DSA:2.60.120.560 335 465 2.3E-16 T 22-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal TOLA_RS04170 6dc50518ed4f7b51489ae2836749c756 471 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 18 444 2.2E-158 T 22-04-2016 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26|UniPathway: UPA00238 TOLA_RS04170 6dc50518ed4f7b51489ae2836749c756 471 Gene3D G3DSA:2.115.10.20 39 334 1.9E-19 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain TOLA_RS04170 6dc50518ed4f7b51489ae2836749c756 471 SUPERFAMILY SSF75005 21 337 3.77E-104 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain TOLA_RS04170 6dc50518ed4f7b51489ae2836749c756 471 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 31 44 - T 22-04-2016 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 TOLA_RS04170 6dc50518ed4f7b51489ae2836749c756 471 PANTHER PTHR30175 20 345 1.0E-99 T 22-04-2016 TOLA_RS04170 6dc50518ed4f7b51489ae2836749c756 471 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 31 336 1.7E-98 T 22-04-2016 IPR013148 Glycosyl hydrolase family 32, N-terminal TOLA_RS04170 6dc50518ed4f7b51489ae2836749c756 471 PANTHER PTHR30175:SF8 20 345 1.0E-99 T 22-04-2016 TOLA_RS04170 6dc50518ed4f7b51489ae2836749c756 471 SMART SM00640 31 433 1.0E-130 T 22-04-2016 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 TOLA_RS01515 46da0434c98d4a3854f10f588763d776 312 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 6 309 9.6E-107 T 22-04-2016 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 TOLA_RS01515 46da0434c98d4a3854f10f588763d776 312 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 6 309 9.9E-107 T 22-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TOLA_RS01515 46da0434c98d4a3854f10f588763d776 312 PANTHER PTHR10584 1 308 4.4E-110 T 22-04-2016 TOLA_RS01515 46da0434c98d4a3854f10f588763d776 312 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 249 262 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TOLA_RS01515 46da0434c98d4a3854f10f588763d776 312 Pfam PF00294 pfkB family carbohydrate kinase 27 294 2.0E-54 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB TOLA_RS01515 46da0434c98d4a3854f10f588763d776 312 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 39 63 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TOLA_RS01515 46da0434c98d4a3854f10f588763d776 312 SUPERFAMILY SSF53613 6 292 5.61E-72 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS01515 46da0434c98d4a3854f10f588763d776 312 Gene3D G3DSA:2.20.150.10 12 38 1.0E-4 T 22-04-2016 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395|UniPathway: UPA00704 TOLA_RS01515 46da0434c98d4a3854f10f588763d776 312 PANTHER PTHR10584:SF170 1 308 4.4E-110 T 22-04-2016 TOLA_RS01515 46da0434c98d4a3854f10f588763d776 312 PIRSF PIRSF000535 2 311 3.5E-99 T 22-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TOLA_RS01515 46da0434c98d4a3854f10f588763d776 312 Gene3D G3DSA:3.40.1190.20 39 311 5.3E-86 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 SUPERFAMILY SSF52440 1 112 4.6E-45 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 PANTHER PTHR18866 1 544 7.7E-282 T 22-04-2016 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 PANTHER PTHR18866 1095 1199 7.7E-282 T 22-04-2016 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 SUPERFAMILY SSF160467 802 893 5.1E-19 T 22-04-2016 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 SUPERFAMILY SSF50891 631 757 1.14E-33 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 SMART SM00797 477 767 1.6E-166 T 22-04-2016 IPR003778 Carboxyltransferase domain, subdomain A and B TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 454 772 3.0E-92 T 22-04-2016 IPR003778 Carboxyltransferase domain, subdomain A and B TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 319 2.6E-61 T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 PANTHER PTHR18866:SF91 1 544 7.7E-282 T 22-04-2016 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 PANTHER PTHR18866:SF91 1095 1199 7.7E-282 T 22-04-2016 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 SUPERFAMILY SSF51230 1123 1199 8.64E-21 T 22-04-2016 IPR011053 Single hybrid motif TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.7E-42 T 22-04-2016 IPR005481 Biotin carboxylase-like, N-terminal domain TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 22-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Pfam PF02626 Allophanate hydrolase subunit 2 478 750 6.3E-86 T 22-04-2016 IPR003778 Carboxyltransferase domain, subdomain A and B TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 SUPERFAMILY SSF56059 83 353 1.17E-59 T 22-04-2016 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Gene3D G3DSA:3.30.1490.20 129 201 1.6E-21 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Gene3D G3DSA:2.40.50.100 1128 1199 1.8E-22 T 22-04-2016 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Gene3D G3DSA:3.30.1360.40 802 881 5.7E-27 T 22-04-2016 IPR024946 Arginine repressor C-terminal-like domain TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Gene3D G3DSA:3.30.470.20 202 447 1.2E-85 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Pfam PF02785 Biotin carboxylase C-terminal domain 338 446 5.0E-31 T 22-04-2016 IPR005482 Biotin carboxylase, C-terminal TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 SMART SM00796 800 1031 3.0E-115 T 22-04-2016 IPR003833 Carboxyltransferase domain, subdomain C and D TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 TIGRFAM TIGR02712 urea_carbox: urea carboxylase 2 1199 0.0 T 22-04-2016 IPR014084 Urea carboxylase KEGG: 00220+3.5.1.54+6.3.4.6|KEGG: 00791+3.5.1.54+6.3.4.6|MetaCyc: PWY-5169|MetaCyc: PWY-5703|UniPathway: UPA00258|UniPathway: UPA00258 TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Gene3D G3DSA:2.40.100.10 917 1054 2.6E-45 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Gene3D G3DSA:2.40.100.10 630 763 3.3E-35 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Gene3D G3DSA:3.40.50.20 1 128 2.9E-45 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 SUPERFAMILY SSF51246 332 448 1.41E-32 T 22-04-2016 IPR011054 Rudiment single hybrid motif TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Pfam PF02682 Allophanate hydrolase subunit 1 801 1022 9.9E-50 T 22-04-2016 IPR003833 Carboxyltransferase domain, subdomain C and D TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 SMART SM00878 338 446 2.5E-43 T 22-04-2016 IPR005482 Biotin carboxylase, C-terminal TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 SUPERFAMILY SSF50891 917 1047 2.2E-26 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS14850 3cad0e1e5f4522839cd0b3f2a9c643d5 1200 Pfam PF00364 Biotin-requiring enzyme 1135 1198 3.6E-17 T 22-04-2016 IPR000089 Biotin/lipoyl attachment TOLA_RS02400 6177655ee6792997f3eead65d3397b6e 106 Pfam PF04269 Protein of unknown function, DUF440 6 104 5.7E-41 T 22-04-2016 IPR007376 dsDNA mimic, putative TOLA_RS02400 6177655ee6792997f3eead65d3397b6e 106 SUPERFAMILY SSF102816 5 104 5.36E-32 T 22-04-2016 IPR007376 dsDNA mimic, putative TOLA_RS02400 6177655ee6792997f3eead65d3397b6e 106 Gene3D G3DSA:3.10.450.140 7 104 1.5E-37 T 22-04-2016 IPR007376 dsDNA mimic, putative TOLA_RS02400 6177655ee6792997f3eead65d3397b6e 106 PIRSF PIRSF004916 1 105 5.9E-31 T 22-04-2016 IPR007376 dsDNA mimic, putative TOLA_RS02400 6177655ee6792997f3eead65d3397b6e 106 ProDom PD020447 UPF0263 YCIU HD0986 VV1228 UNCHARACTERIZED 3D-STRUCTURE VV13059 BCR PM0536 VC1208 7 104 3.0E-19 T 22-04-2016 IPR007376 dsDNA mimic, putative TOLA_RS11370 b452b4a95c68400495d763ed761b648b 411 Pfam PF02687 FtsX-like permease family 277 404 1.1E-17 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 TOLA_RS11370 b452b4a95c68400495d763ed761b648b 411 PANTHER PTHR30489 5 411 3.8E-155 T 22-04-2016 TOLA_RS11370 b452b4a95c68400495d763ed761b648b 411 PANTHER PTHR30489:SF8 5 411 3.8E-155 T 22-04-2016 TOLA_RS11370 b452b4a95c68400495d763ed761b648b 411 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 8 411 1.4E-137 T 22-04-2016 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 TOLA_RS11370 b452b4a95c68400495d763ed761b648b 411 Pfam PF12704 MacB-like periplasmic core domain 31 215 1.8E-14 T 22-04-2016 IPR025857 MacB-like periplasmic core domain TOLA_RS06765 0d1a577e5065109b22f0439346b473c1 300 Gene3D G3DSA:3.40.190.10 180 264 3.7E-12 T 22-04-2016 TOLA_RS06765 0d1a577e5065109b22f0439346b473c1 300 Gene3D G3DSA:3.40.190.10 94 179 2.9E-20 T 22-04-2016 TOLA_RS06765 0d1a577e5065109b22f0439346b473c1 300 SUPERFAMILY SSF53850 92 295 2.48E-42 T 22-04-2016 TOLA_RS06765 0d1a577e5065109b22f0439346b473c1 300 PANTHER PTHR30537:SF1 1 294 5.0E-151 T 22-04-2016 TOLA_RS06765 0d1a577e5065109b22f0439346b473c1 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 3.9E-20 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS06765 0d1a577e5065109b22f0439346b473c1 300 Pfam PF03466 LysR substrate binding domain 90 294 4.8E-41 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS06765 0d1a577e5065109b22f0439346b473c1 300 PANTHER PTHR30537 1 294 5.0E-151 T 22-04-2016 TOLA_RS06765 0d1a577e5065109b22f0439346b473c1 300 SUPERFAMILY SSF46785 5 114 7.58E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06765 0d1a577e5065109b22f0439346b473c1 300 Gene3D G3DSA:1.10.10.10 5 80 8.4E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08885 41886f72c301476adee0892067961694 143 SMART SM00422 1 70 3.0E-25 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TOLA_RS08885 41886f72c301476adee0892067961694 143 Gene3D G3DSA:1.10.1660.10 56 129 1.4E-24 T 22-04-2016 TOLA_RS08885 41886f72c301476adee0892067961694 143 PANTHER PTHR30204 1 112 8.3E-41 T 22-04-2016 TOLA_RS08885 41886f72c301476adee0892067961694 143 SUPERFAMILY SSF46955 1 123 9.52E-36 T 22-04-2016 IPR009061 Putative DNA-binding domain TOLA_RS08885 41886f72c301476adee0892067961694 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.1E-7 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TOLA_RS08885 41886f72c301476adee0892067961694 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.1E-7 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TOLA_RS08885 41886f72c301476adee0892067961694 143 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.1E-7 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TOLA_RS08885 41886f72c301476adee0892067961694 143 PANTHER PTHR30204:SF18 1 112 8.3E-41 T 22-04-2016 TOLA_RS08885 41886f72c301476adee0892067961694 143 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.1E-18 T 22-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TOLA_RS08885 41886f72c301476adee0892067961694 143 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 127 8.8E-50 T 22-04-2016 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 TOLA_RS08885 41886f72c301476adee0892067961694 143 Gene3D G3DSA:1.10.1660.10 1 55 1.7E-25 T 22-04-2016 TOLA_RS07525 29d9036460385e5c4e95160be7314336 220 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 216 32.886 T 22-04-2016 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67 TOLA_RS07525 29d9036460385e5c4e95160be7314336 220 PANTHER PTHR10259:SF16 1 215 1.1E-50 T 22-04-2016 TOLA_RS07525 29d9036460385e5c4e95160be7314336 220 PIRSF PIRSF023956 1 217 2.0E-66 T 22-04-2016 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67 TOLA_RS07525 29d9036460385e5c4e95160be7314336 220 SUPERFAMILY SSF53335 1 193 3.79E-43 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07525 29d9036460385e5c4e95160be7314336 220 PANTHER PTHR10259 1 215 1.1E-50 T 22-04-2016 TOLA_RS07525 29d9036460385e5c4e95160be7314336 220 Gene3D G3DSA:3.40.50.150 16 214 9.0E-48 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07525 29d9036460385e5c4e95160be7314336 220 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 215 2.0E-57 T 22-04-2016 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67 TOLA_RS02010 2e9d883615585d19f5c267f856b9ff04 317 PANTHER PTHR30606:SF5 8 317 5.8E-140 T 22-04-2016 TOLA_RS02010 2e9d883615585d19f5c267f856b9ff04 317 PIRSF PIRSF026649 9 311 9.0E-93 T 22-04-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 TOLA_RS02010 2e9d883615585d19f5c267f856b9ff04 317 PANTHER PTHR30606 8 317 5.8E-140 T 22-04-2016 TOLA_RS02010 2e9d883615585d19f5c267f856b9ff04 317 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 12 311 2.4E-125 T 22-04-2016 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24|UniPathway: UPA00030 TOLA_RS02010 2e9d883615585d19f5c267f856b9ff04 317 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 18 301 1.6E-86 T 22-04-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 TOLA_RS02010 2e9d883615585d19f5c267f856b9ff04 317 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 10 311 49.332 T 22-04-2016 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24|UniPathway: UPA00030 TOLA_RS05175 958db42c4768635da2f045780eb0aeb5 347 PANTHER PTHR34184 30 347 2.9E-155 T 22-04-2016 TOLA_RS05175 958db42c4768635da2f045780eb0aeb5 347 PANTHER PTHR34184:SF2 30 347 2.9E-155 T 22-04-2016 TOLA_RS05175 958db42c4768635da2f045780eb0aeb5 347 Pfam PF03773 Predicted permease 51 344 9.2E-75 T 22-04-2016 IPR005524 Predicted permease DUF318 TOLA_RS06210 ae9813c772451efacd162ce204549bab 318 PANTHER PTHR30238:SF0 5 313 3.0E-146 T 22-04-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 TOLA_RS06210 ae9813c772451efacd162ce204549bab 318 PANTHER PTHR30238 5 313 3.0E-146 T 22-04-2016 TOLA_RS06210 ae9813c772451efacd162ce204549bab 318 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 7 312 7.8E-122 T 22-04-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 TOLA_RS06210 ae9813c772451efacd162ce204549bab 318 Pfam PF03741 Integral membrane protein TerC family 79 282 2.6E-55 T 22-04-2016 IPR005496 Integral membrane protein TerC GO:0016021 TOLA_RS15805 d9e9a0d0da3324d749e71f9750ad395d 463 Gene3D G3DSA:1.25.40.10 53 194 2.2E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS15805 d9e9a0d0da3324d749e71f9750ad395d 463 Pfam PF03412 Peptidase C39 family 188 292 2.1E-9 T 22-04-2016 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 TOLA_RS15805 d9e9a0d0da3324d749e71f9750ad395d 463 Gene3D G3DSA:3.90.70.10 195 296 2.9E-6 T 22-04-2016 TOLA_RS15805 d9e9a0d0da3324d749e71f9750ad395d 463 SUPERFAMILY SSF48452 51 169 1.9E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS03375 24eb763a2cb859b1ef633fdf5e4de1d3 457 TIGRFAM TIGR01283 nifE: nitrogenase MoFe cofactor biosynthesis protein NifE 4 456 3.7E-210 T 22-04-2016 IPR005973 Nitrogenase MoFe cofactor biosynthesis protein NifE GO:0006461|GO:0009399 UniPathway: UPA00782 TOLA_RS03375 24eb763a2cb859b1ef633fdf5e4de1d3 457 Gene3D G3DSA:3.40.50.1980 321 457 5.3E-50 T 22-04-2016 TOLA_RS03375 24eb763a2cb859b1ef633fdf5e4de1d3 457 Gene3D G3DSA:3.40.50.1980 37 177 1.1E-42 T 22-04-2016 TOLA_RS03375 24eb763a2cb859b1ef633fdf5e4de1d3 457 PANTHER PTHR33712:SF6 30 457 1.1E-176 T 22-04-2016 TOLA_RS03375 24eb763a2cb859b1ef633fdf5e4de1d3 457 Gene3D G3DSA:3.40.50.1980 178 294 1.1E-40 T 22-04-2016 TOLA_RS03375 24eb763a2cb859b1ef633fdf5e4de1d3 457 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 37 442 5.2E-103 T 22-04-2016 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 TOLA_RS03375 24eb763a2cb859b1ef633fdf5e4de1d3 457 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 122 136 - T 22-04-2016 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TOLA_RS03375 24eb763a2cb859b1ef633fdf5e4de1d3 457 PANTHER PTHR33712 30 457 1.1E-176 T 22-04-2016 TOLA_RS03375 24eb763a2cb859b1ef633fdf5e4de1d3 457 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 55 62 - T 22-04-2016 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TOLA_RS03375 24eb763a2cb859b1ef633fdf5e4de1d3 457 SUPERFAMILY SSF53807 4 452 1.91E-133 T 22-04-2016 TOLA_RS04755 94a84dcff9024c0299939df2b6bdfbf3 195 PANTHER PTHR23407 1 195 1.1E-61 T 22-04-2016 TOLA_RS04755 94a84dcff9024c0299939df2b6bdfbf3 195 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 9 188 3.0E-42 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase TOLA_RS04755 94a84dcff9024c0299939df2b6bdfbf3 195 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 9 188 5.2E-53 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase TOLA_RS04755 94a84dcff9024c0299939df2b6bdfbf3 195 PIRSF PIRSF006806 1 191 3.2E-38 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase TOLA_RS04755 94a84dcff9024c0299939df2b6bdfbf3 195 PANTHER PTHR23407:SF1 1 195 1.1E-61 T 22-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase TOLA_RS04755 94a84dcff9024c0299939df2b6bdfbf3 195 SUPERFAMILY SSF100950 5 194 5.3E-56 T 22-04-2016 TOLA_RS04755 94a84dcff9024c0299939df2b6bdfbf3 195 Gene3D G3DSA:3.40.50.10420 8 194 8.6E-56 T 22-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain TOLA_RS03245 580733a0fab29a76cf936c5d12d90e65 514 Gene3D G3DSA:2.40.440.10 274 321 1.1E-12 T 22-04-2016 TOLA_RS03245 580733a0fab29a76cf936c5d12d90e65 514 Gene3D G3DSA:2.40.440.10 385 434 1.1E-12 T 22-04-2016 TOLA_RS03245 580733a0fab29a76cf936c5d12d90e65 514 Pfam PF03734 L,D-transpeptidase catalytic domain 276 444 6.3E-28 T 22-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 TOLA_RS03245 580733a0fab29a76cf936c5d12d90e65 514 SUPERFAMILY SSF47090 174 257 4.39E-13 T 22-04-2016 IPR002477 Peptidoglycan binding-like TOLA_RS03245 580733a0fab29a76cf936c5d12d90e65 514 Gene3D G3DSA:1.10.101.10 178 255 2.0E-14 T 22-04-2016 IPR002477 Peptidoglycan binding-like TOLA_RS03245 580733a0fab29a76cf936c5d12d90e65 514 SUPERFAMILY SSF141523 275 330 9.94E-19 T 22-04-2016 TOLA_RS03245 580733a0fab29a76cf936c5d12d90e65 514 SUPERFAMILY SSF141523 383 434 9.94E-19 T 22-04-2016 TOLA_RS03245 580733a0fab29a76cf936c5d12d90e65 514 PANTHER PTHR41533:SF1 143 502 5.4E-82 T 22-04-2016 TOLA_RS03245 580733a0fab29a76cf936c5d12d90e65 514 PANTHER PTHR41533 143 502 5.4E-82 T 22-04-2016 TOLA_RS03245 580733a0fab29a76cf936c5d12d90e65 514 Pfam PF01471 Putative peptidoglycan binding domain 215 249 5.4E-9 T 22-04-2016 IPR002477 Peptidoglycan binding-like TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 Gene3D G3DSA:3.40.1360.10 237 362 2.2E-44 T 22-04-2016 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 SMART SM00400 36 90 1.5E-34 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 Gene3D G3DSA:1.10.860.10 437 578 3.7E-34 T 22-04-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 SUPERFAMILY SSF57783 5 99 4.25E-38 T 22-04-2016 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 SMART SM00493 255 326 1.2E-16 T 22-04-2016 IPR006171 Toprim domain TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 Gene3D G3DSA:3.90.580.10 2 100 1.0E-40 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 PIRSF PIRSF002811 2 580 5.2E-146 T 22-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 Pfam PF10410 DnaB-helicase binding domain of primase 366 419 6.3E-7 T 22-04-2016 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 Gene3D G3DSA:1.20.50.20 365 412 4.5E-7 T 22-04-2016 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 TIGRFAM TIGR01391 dnaG: DNA primase 5 413 3.5E-144 T 22-04-2016 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 SMART SM00766 452 574 9.2E-24 T 22-04-2016 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 PANTHER PTHR30313 3 461 8.3E-155 T 22-04-2016 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 SUPERFAMILY SSF117023 449 577 3.14E-28 T 22-04-2016 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 Pfam PF08275 DNA primase catalytic core, N-terminal domain 124 247 1.4E-42 T 22-04-2016 IPR013264 DNA primase, catalytic core, N-terminal TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 Pfam PF13662 Toprim domain 256 321 4.0E-14 T 22-04-2016 IPR006171 Toprim domain TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 Pfam PF01807 CHC2 zinc finger 6 100 4.3E-40 T 22-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 Gene3D G3DSA:3.90.980.10 115 236 4.5E-46 T 22-04-2016 IPR013264 DNA primase, catalytic core, N-terminal TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 Hamap MF_00974 DNA primase [dnaG]. 4 575 29.045 T 22-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 SUPERFAMILY SSF56731 115 417 8.72E-109 T 22-04-2016 TOLA_RS13585 dbee6521d778bb63e4fc3917288b53af 582 Pfam PF08278 DNA primase DnaG DnaB-binding 454 572 8.8E-25 T 22-04-2016 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 TOLA_RS15830 f850138d38c427776c350a3ed1d19a4a 467 Gene3D G3DSA:3.40.50.720 5 262 3.9E-85 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS15830 f850138d38c427776c350a3ed1d19a4a 467 PANTHER PTHR30562 9 458 8.9E-182 T 22-04-2016 TOLA_RS15830 f850138d38c427776c350a3ed1d19a4a 467 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 199 435 2.9E-73 T 22-04-2016 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 TOLA_RS15830 f850138d38c427776c350a3ed1d19a4a 467 PRINTS PR00084 Mannitol dehydrogenase signature 159 172 2.4E-15 T 22-04-2016 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS15830 f850138d38c427776c350a3ed1d19a4a 467 PRINTS PR00084 Mannitol dehydrogenase signature 199 212 2.4E-15 T 22-04-2016 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS15830 f850138d38c427776c350a3ed1d19a4a 467 PRINTS PR00084 Mannitol dehydrogenase signature 229 244 2.4E-15 T 22-04-2016 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS15830 f850138d38c427776c350a3ed1d19a4a 467 PRINTS PR00084 Mannitol dehydrogenase signature 9 19 2.4E-15 T 22-04-2016 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS15830 f850138d38c427776c350a3ed1d19a4a 467 SUPERFAMILY SSF48179 265 454 1.67E-44 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS15830 f850138d38c427776c350a3ed1d19a4a 467 PANTHER PTHR30562:SF4 9 458 8.9E-182 T 22-04-2016 TOLA_RS15830 f850138d38c427776c350a3ed1d19a4a 467 Gene3D G3DSA:1.10.1040.10 265 454 7.8E-50 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TOLA_RS15830 f850138d38c427776c350a3ed1d19a4a 467 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 9 168 3.1E-36 T 22-04-2016 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 TOLA_RS15830 f850138d38c427776c350a3ed1d19a4a 467 SUPERFAMILY SSF51735 6 262 1.1E-72 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS12965 170c3eb5d4a61e39fed6ab66cb6a99e4 156 PANTHER PTHR33507 9 154 1.9E-31 T 22-04-2016 TOLA_RS12965 170c3eb5d4a61e39fed6ab66cb6a99e4 156 Gene3D G3DSA:2.40.50.140 97 151 5.5E-12 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS12965 170c3eb5d4a61e39fed6ab66cb6a99e4 156 SUPERFAMILY SSF141322 111 153 2.62E-6 T 22-04-2016 TOLA_RS12965 170c3eb5d4a61e39fed6ab66cb6a99e4 156 PANTHER PTHR33507:SF3 9 154 1.9E-31 T 22-04-2016 TOLA_RS12965 170c3eb5d4a61e39fed6ab66cb6a99e4 156 Pfam PF01957 NfeD-like C-terminal, partner-binding 16 150 5.6E-21 T 22-04-2016 IPR002810 NfeD-like, C-terminal domain TOLA_RS07690 3055ac9a578de02e3df1e863cfb54b9b 207 Gene3D G3DSA:2.50.20.10 24 197 6.3E-6 T 22-04-2016 TOLA_RS07690 3055ac9a578de02e3df1e863cfb54b9b 207 SUPERFAMILY SSF89392 120 206 6.67E-7 T 22-04-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX TOLA_RS07690 3055ac9a578de02e3df1e863cfb54b9b 207 SUPERFAMILY SSF89392 19 85 6.67E-7 T 22-04-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX TOLA_RS14330 e9faa9ce185accc8742c224b23b491e7 498 Gene3D G3DSA:3.40.50.1220 325 498 1.1E-89 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain TOLA_RS14330 e9faa9ce185accc8742c224b23b491e7 498 PIRSF PIRSF000204 1 498 2.4E-225 T 22-04-2016 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 TOLA_RS14330 e9faa9ce185accc8742c224b23b491e7 498 PANTHER PTHR10160 4 124 1.6E-235 T 22-04-2016 TOLA_RS14330 e9faa9ce185accc8742c224b23b491e7 498 PANTHER PTHR10160 158 498 1.6E-235 T 22-04-2016 TOLA_RS14330 e9faa9ce185accc8742c224b23b491e7 498 SUPERFAMILY SSF52467 325 498 2.68E-76 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain TOLA_RS14330 e9faa9ce185accc8742c224b23b491e7 498 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 496 1.7E-192 T 22-04-2016 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 TOLA_RS14340 4db9b3d7cf21eb4f1eff1e67aea95986 308 Pfam PF13511 Domain of unknown function (DUF4124) 18 53 9.3E-10 T 22-04-2016 IPR025392 Domain of unknown function DUF4124 TOLA_RS14340 4db9b3d7cf21eb4f1eff1e67aea95986 308 PANTHER PTHR21666 150 294 2.4E-25 T 22-04-2016 TOLA_RS14340 4db9b3d7cf21eb4f1eff1e67aea95986 308 Pfam PF01551 Peptidase family M23 179 279 6.5E-25 T 22-04-2016 IPR016047 Peptidase M23 TOLA_RS14340 4db9b3d7cf21eb4f1eff1e67aea95986 308 Gene3D G3DSA:2.70.70.10 146 278 3.1E-33 T 22-04-2016 TOLA_RS14340 4db9b3d7cf21eb4f1eff1e67aea95986 308 SUPERFAMILY SSF51261 146 278 2.41E-32 T 22-04-2016 IPR011055 Duplicated hybrid motif TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 SUPERFAMILY SSF63418 6 90 3.01E-18 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 Pfam PF01225 Mur ligase family, catalytic domain 17 89 7.7E-9 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 PANTHER PTHR23135 1 477 2.7E-194 T 22-04-2016 TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 Gene3D G3DSA:3.40.1190.10 92 328 3.3E-78 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 477 33.142 T 22-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 PANTHER PTHR23135:SF4 1 477 2.7E-194 T 22-04-2016 TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 Pfam PF02875 Mur ligase family, glutamate ligase domain 325 411 2.7E-24 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 15 477 9.1E-164 T 22-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 Gene3D G3DSA:3.40.1390.10 4 90 1.0E-20 T 22-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 Pfam PF08245 Mur ligase middle domain 101 305 2.6E-51 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 Gene3D G3DSA:3.90.190.20 329 471 9.7E-60 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 SUPERFAMILY SSF53244 325 477 7.94E-52 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS02695 1df11ca226e8cdde6b69f954c1c4dd16 481 SUPERFAMILY SSF53623 92 324 9.03E-73 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS13060 ea4b0f8d5edae4770b370c04a5bd82b2 342 PANTHER PTHR30469 25 334 7.9E-68 T 22-04-2016 TOLA_RS13060 ea4b0f8d5edae4770b370c04a5bd82b2 342 Gene3D G3DSA:2.40.50.100 51 82 1.0E-12 T 22-04-2016 TOLA_RS13060 ea4b0f8d5edae4770b370c04a5bd82b2 342 Gene3D G3DSA:2.40.50.100 157 186 1.0E-12 T 22-04-2016 TOLA_RS13060 ea4b0f8d5edae4770b370c04a5bd82b2 342 SUPERFAMILY SSF111369 41 255 1.44E-22 T 22-04-2016 TOLA_RS13060 ea4b0f8d5edae4770b370c04a5bd82b2 342 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 50 251 1.1E-12 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TOLA_RS13060 ea4b0f8d5edae4770b370c04a5bd82b2 342 PANTHER PTHR30469:SF15 25 334 7.9E-68 T 22-04-2016 TOLA_RS13060 ea4b0f8d5edae4770b370c04a5bd82b2 342 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 26 325 2.2E-54 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 Gene3D G3DSA:3.30.1360.120 2 120 1.8E-40 T 22-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 PANTHER PTHR11649 7 453 8.8E-165 T 22-04-2016 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 PANTHER PTHR11649:SF56 7 453 8.8E-165 T 22-04-2016 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 119 4.9E-33 T 22-04-2016 IPR018948 GTP-binding protein TrmE, N-terminal TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 215 370 1.1E-21 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 453 32.76 T 22-04-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 Pfam PF12631 MnmE helical domain 122 450 2.5E-59 T 22-04-2016 IPR025867 MnmE, helical domain TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 Pfam PF01926 50S ribosome-binding GTPase 217 304 4.5E-23 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 Gene3D G3DSA:1.20.120.430 383 453 1.8E-58 T 22-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 Gene3D G3DSA:1.20.120.430 240 270 1.8E-58 T 22-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 Gene3D G3DSA:1.20.120.430 121 181 1.8E-58 T 22-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 10 453 1.2E-101 T 22-04-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 Gene3D G3DSA:3.40.50.300 212 239 5.3E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 SUPERFAMILY SSF116878 120 219 2.48E-50 T 22-04-2016 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 SUPERFAMILY SSF116878 378 453 2.48E-50 T 22-04-2016 TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 SUPERFAMILY SSF52540 196 371 9.77E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 SUPERFAMILY SSF52540 71 162 9.77E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS16235 356103cc595957b2b4558e36826e9482 453 Gene3D G3DSA:3.40.50.300 285 374 1.4E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PANTHER PTHR22912:SF48 1 315 1.0E-161 T 22-04-2016 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 SUPERFAMILY SSF51905 2 313 4.75E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 301 3.2E-46 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 Gene3D G3DSA:3.50.50.60 234 314 3.0E-8 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PANTHER PTHR22912 1 315 1.0E-161 T 22-04-2016 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 22-04-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 Gene3D G3DSA:3.50.50.60 5 119 6.4E-34 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 3.47E-37 T 22-04-2016 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 3.47E-37 T 22-04-2016 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 3.47E-37 T 22-04-2016 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 3.47E-37 T 22-04-2016 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.47E-37 T 22-04-2016 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 Gene3D G3DSA:3.50.50.60 120 233 6.8E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 7.94E-74 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 7.94E-74 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 7.94E-74 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 7.94E-74 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 7.94E-74 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 7.94E-74 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 7.94E-74 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 7.94E-74 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 7.94E-74 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS11775 e69f3d000ef752ca05b35b708897b7c4 318 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 313 6.0E-120 T 22-04-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 TOLA_RS00675 a66448a5aeaa9957bfbffca3171b1d34 93 ProSitePatterns PS00150 Acylphosphatase signature 1. 11 21 - T 22-04-2016 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TOLA_RS00675 a66448a5aeaa9957bfbffca3171b1d34 93 SUPERFAMILY SSF54975 4 83 3.05E-27 T 22-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TOLA_RS00675 a66448a5aeaa9957bfbffca3171b1d34 93 PRINTS PR00112 Acylphosphatase signature 27 52 5.7E-6 T 22-04-2016 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TOLA_RS00675 a66448a5aeaa9957bfbffca3171b1d34 93 PRINTS PR00112 Acylphosphatase signature 6 21 5.7E-6 T 22-04-2016 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TOLA_RS00675 a66448a5aeaa9957bfbffca3171b1d34 93 Gene3D G3DSA:3.30.70.100 6 89 1.1E-29 T 22-04-2016 TOLA_RS00675 a66448a5aeaa9957bfbffca3171b1d34 93 Pfam PF00708 Acylphosphatase 5 90 8.7E-26 T 22-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TOLA_RS00675 a66448a5aeaa9957bfbffca3171b1d34 93 PANTHER PTHR10029 6 81 1.6E-28 T 22-04-2016 TOLA_RS03380 125ec2a461657f02767039ce32173a3e 460 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 20 428 1.9E-96 T 22-04-2016 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 TOLA_RS03380 125ec2a461657f02767039ce32173a3e 460 PANTHER PTHR33712:SF2 15 203 3.2E-61 T 22-04-2016 TOLA_RS03380 125ec2a461657f02767039ce32173a3e 460 PANTHER PTHR33712:SF2 223 428 3.2E-61 T 22-04-2016 TOLA_RS03380 125ec2a461657f02767039ce32173a3e 460 Gene3D G3DSA:3.40.50.1980 167 265 3.0E-24 T 22-04-2016 TOLA_RS03380 125ec2a461657f02767039ce32173a3e 460 SUPERFAMILY SSF53807 6 429 6.54E-109 T 22-04-2016 TOLA_RS03380 125ec2a461657f02767039ce32173a3e 460 TIGRFAM TIGR01285 nifN: nitrogenase molybdenum-iron cofactor biosynthesis protein NifN 2 431 2.5E-176 T 22-04-2016 IPR005975 Nitrogenase molybdenum-iron cofactor biosynthesis protein GO:0006461|GO:0009399 UniPathway: UPA00782 TOLA_RS03380 125ec2a461657f02767039ce32173a3e 460 Gene3D G3DSA:3.40.50.1980 294 404 3.7E-28 T 22-04-2016 TOLA_RS03380 125ec2a461657f02767039ce32173a3e 460 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 37 44 - T 22-04-2016 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TOLA_RS03380 125ec2a461657f02767039ce32173a3e 460 PANTHER PTHR33712 15 203 3.2E-61 T 22-04-2016 TOLA_RS03380 125ec2a461657f02767039ce32173a3e 460 PANTHER PTHR33712 223 428 3.2E-61 T 22-04-2016 TOLA_RS03380 125ec2a461657f02767039ce32173a3e 460 Gene3D G3DSA:3.40.50.1980 20 161 2.2E-37 T 22-04-2016 TOLA_RS04065 2e1ae96ee8ce1bcaf2000af65dcb3273 301 PANTHER PTHR21708 1 297 3.4E-65 T 22-04-2016 TOLA_RS04065 2e1ae96ee8ce1bcaf2000af65dcb3273 301 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 297 1.5E-64 T 22-04-2016 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 TOLA_RS04065 2e1ae96ee8ce1bcaf2000af65dcb3273 301 SUPERFAMILY SSF48179 177 295 5.78E-29 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS04065 2e1ae96ee8ce1bcaf2000af65dcb3273 301 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 175 294 3.3E-28 T 22-04-2016 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 TOLA_RS04065 2e1ae96ee8ce1bcaf2000af65dcb3273 301 Gene3D G3DSA:3.40.50.720 1 181 2.4E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04065 2e1ae96ee8ce1bcaf2000af65dcb3273 301 Gene3D G3DSA:1.10.1040.10 182 296 8.1E-35 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TOLA_RS04065 2e1ae96ee8ce1bcaf2000af65dcb3273 301 SUPERFAMILY SSF51735 1 172 5.91E-42 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04065 2e1ae96ee8ce1bcaf2000af65dcb3273 301 PANTHER PTHR21708:SF24 1 297 3.4E-65 T 22-04-2016 TOLA_RS04065 2e1ae96ee8ce1bcaf2000af65dcb3273 301 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 149 2.4E-25 T 22-04-2016 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 TOLA_RS11270 cb0eab15042bc9bd78758dfca5d2c744 220 PANTHER PTHR38108:SF1 7 220 9.8E-22 T 22-04-2016 TOLA_RS11270 cb0eab15042bc9bd78758dfca5d2c744 220 PANTHER PTHR38108 7 220 9.8E-22 T 22-04-2016 TOLA_RS11270 cb0eab15042bc9bd78758dfca5d2c744 220 Pfam PF09829 Uncharacterized protein conserved in bacteria (DUF2057) 29 215 4.6E-45 T 22-04-2016 IPR018635 Uncharacterised protein family UPF0319 TOLA_RS10350 3f848e7e6ecf0f1cc45bc8004d40e8b9 99 SUPERFAMILY SSF81301 7 90 6.27E-10 T 22-04-2016 TOLA_RS10350 3f848e7e6ecf0f1cc45bc8004d40e8b9 99 Gene3D G3DSA:3.30.460.10 2 98 3.5E-13 T 22-04-2016 TOLA_RS03965 eaaf3db72b27df5f4fcf3b036d8f9005 153 PANTHER PTHR30295 3 153 6.3E-62 T 22-04-2016 TOLA_RS03965 eaaf3db72b27df5f4fcf3b036d8f9005 153 PIRSF PIRSF005900 1 153 4.3E-44 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 TOLA_RS03965 eaaf3db72b27df5f4fcf3b036d8f9005 153 SUPERFAMILY SSF47240 3 153 1.86E-46 T 22-04-2016 IPR009078 Ferritin-like superfamily TOLA_RS03965 eaaf3db72b27df5f4fcf3b036d8f9005 153 Gene3D G3DSA:1.20.1260.10 1 153 5.0E-62 T 22-04-2016 IPR012347 Ferritin-related TOLA_RS03965 eaaf3db72b27df5f4fcf3b036d8f9005 153 PANTHER PTHR30295:SF6 3 153 6.3E-62 T 22-04-2016 TOLA_RS03965 eaaf3db72b27df5f4fcf3b036d8f9005 153 Pfam PF00210 Ferritin-like domain 16 153 2.1E-29 T 22-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TOLA_RS03965 eaaf3db72b27df5f4fcf3b036d8f9005 153 ProSitePatterns PS00819 Dps protein family signature 2. 61 75 - T 22-04-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 TOLA_RS03965 eaaf3db72b27df5f4fcf3b036d8f9005 153 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 35 51 2.7E-10 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 TOLA_RS03965 eaaf3db72b27df5f4fcf3b036d8f9005 153 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 59 75 2.7E-10 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 TOLA_RS03965 eaaf3db72b27df5f4fcf3b036d8f9005 153 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 130 148 2.7E-10 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 TOLA_RS03965 eaaf3db72b27df5f4fcf3b036d8f9005 153 ProSitePatterns PS00818 Dps protein family signature 1. 35 51 - T 22-04-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 TOLA_RS13210 233d9db72d77d98d2249e7e293c3af4f 408 TIGRFAM TIGR01696 deoB: phosphopentomutase 3 400 3.3E-162 T 22-04-2016 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 TOLA_RS13210 233d9db72d77d98d2249e7e293c3af4f 408 Pfam PF01676 Metalloenzyme superfamily 2 394 4.9E-39 T 22-04-2016 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TOLA_RS13210 233d9db72d77d98d2249e7e293c3af4f 408 Gene3D G3DSA:3.40.720.10 1 113 1.6E-68 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 TOLA_RS13210 233d9db72d77d98d2249e7e293c3af4f 408 Gene3D G3DSA:3.40.720.10 237 404 1.6E-68 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 TOLA_RS13210 233d9db72d77d98d2249e7e293c3af4f 408 SUPERFAMILY SSF143856 117 233 1.44E-48 T 22-04-2016 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 TOLA_RS13210 233d9db72d77d98d2249e7e293c3af4f 408 Gene3D G3DSA:3.30.70.1250 114 233 1.7E-51 T 22-04-2016 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 TOLA_RS13210 233d9db72d77d98d2249e7e293c3af4f 408 PANTHER PTHR21110 2 408 1.4E-143 T 22-04-2016 TOLA_RS13210 233d9db72d77d98d2249e7e293c3af4f 408 Hamap MF_00740 Phosphopentomutase [deoB]. 1 404 52.32 T 22-04-2016 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 TOLA_RS13210 233d9db72d77d98d2249e7e293c3af4f 408 SUPERFAMILY SSF53649 1 114 1.13E-70 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 TOLA_RS13210 233d9db72d77d98d2249e7e293c3af4f 408 SUPERFAMILY SSF53649 234 402 1.13E-70 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 TOLA_RS13210 233d9db72d77d98d2249e7e293c3af4f 408 PIRSF PIRSF001491 1 407 1.7E-154 T 22-04-2016 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 TOLA_RS13210 233d9db72d77d98d2249e7e293c3af4f 408 PANTHER PTHR21110:SF0 2 408 1.4E-143 T 22-04-2016 TOLA_RS07080 a40e4349672e10367c4eec1b64ae3ac5 456 PANTHER PTHR11236:SF18 4 455 7.5E-166 T 22-04-2016 TOLA_RS07080 a40e4349672e10367c4eec1b64ae3ac5 456 Pfam PF00425 chorismate binding enzyme 191 445 6.9E-97 T 22-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal TOLA_RS07080 a40e4349672e10367c4eec1b64ae3ac5 456 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 106 447 1.5E-119 T 22-04-2016 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543|UniPathway: UPA00077 TOLA_RS07080 a40e4349672e10367c4eec1b64ae3ac5 456 PRINTS PR00095 Anthranilate synthase component I signature 387 401 2.1E-16 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS07080 a40e4349672e10367c4eec1b64ae3ac5 456 PRINTS PR00095 Anthranilate synthase component I signature 307 320 2.1E-16 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS07080 a40e4349672e10367c4eec1b64ae3ac5 456 PRINTS PR00095 Anthranilate synthase component I signature 293 306 2.1E-16 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS07080 a40e4349672e10367c4eec1b64ae3ac5 456 PRINTS PR00095 Anthranilate synthase component I signature 402 416 2.1E-16 T 22-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS07080 a40e4349672e10367c4eec1b64ae3ac5 456 Pfam PF04715 Anthranilate synthase component I, N terminal region 15 152 1.3E-27 T 22-04-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS07080 a40e4349672e10367c4eec1b64ae3ac5 456 PANTHER PTHR11236 4 455 7.5E-166 T 22-04-2016 TOLA_RS07080 a40e4349672e10367c4eec1b64ae3ac5 456 SUPERFAMILY SSF56322 12 454 1.44E-142 T 22-04-2016 IPR005801 ADC synthase GO:0009058 TOLA_RS07080 a40e4349672e10367c4eec1b64ae3ac5 456 Gene3D G3DSA:3.60.120.10 8 454 2.2E-153 T 22-04-2016 IPR005801 ADC synthase GO:0009058 TOLA_RS13285 e9795e5290d00f7468f4427d21795d62 224 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS13285 e9795e5290d00f7468f4427d21795d62 224 PANTHER PTHR11749:SF7 2 223 1.4E-140 T 22-04-2016 TOLA_RS13285 e9795e5290d00f7468f4427d21795d62 224 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 216 1.5E-98 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS13285 e9795e5290d00f7468f4427d21795d62 224 SUPERFAMILY SSF51366 3 218 1.84E-76 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TOLA_RS13285 e9795e5290d00f7468f4427d21795d62 224 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS13285 e9795e5290d00f7468f4427d21795d62 224 Gene3D G3DSA:3.20.20.70 1 222 2.1E-96 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS13285 e9795e5290d00f7468f4427d21795d62 224 PANTHER PTHR11749 2 223 1.4E-140 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS13285 e9795e5290d00f7468f4427d21795d62 224 PIRSF PIRSF001461 1 224 3.7E-106 T 22-04-2016 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS13285 e9795e5290d00f7468f4427d21795d62 224 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 203 2.6E-92 T 22-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TOLA_RS03035 ce7dcf23b373d2a7634529f02317a3a4 65 Pfam PF00403 Heavy-metal-associated domain 3 61 1.4E-9 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TOLA_RS03035 ce7dcf23b373d2a7634529f02317a3a4 65 Gene3D G3DSA:3.30.70.100 2 61 5.1E-20 T 22-04-2016 TOLA_RS03035 ce7dcf23b373d2a7634529f02317a3a4 65 ProSitePatterns PS01047 Heavy-metal-associated domain. 6 35 - T 22-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TOLA_RS03035 ce7dcf23b373d2a7634529f02317a3a4 65 SUPERFAMILY SSF55008 2 62 1.96E-15 T 22-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TOLA_RS15180 e29674aa6cc5fdcbdaf47618127b458a 398 Pfam PF06965 Na+/H+ antiporter 1 7 379 5.4E-147 T 22-04-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TOLA_RS15180 e29674aa6cc5fdcbdaf47618127b458a 398 PANTHER PTHR30341:SF0 1 393 1.5E-173 T 22-04-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TOLA_RS15180 e29674aa6cc5fdcbdaf47618127b458a 398 Gene3D G3DSA:1.20.1530.10 5 384 5.4E-151 T 22-04-2016 IPR023171 Na/H antiporter domain TOLA_RS15180 e29674aa6cc5fdcbdaf47618127b458a 398 PANTHER PTHR30341 1 393 1.5E-173 T 22-04-2016 TOLA_RS15180 e29674aa6cc5fdcbdaf47618127b458a 398 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 5 385 23.248 T 22-04-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TOLA_RS15180 e29674aa6cc5fdcbdaf47618127b458a 398 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 8 379 1.2E-152 T 22-04-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TOLA_RS00935 59fe6d8c75e5f253a0fd821d318a63d3 93 SUPERFAMILY SSF54534 6 90 2.29E-28 T 22-04-2016 TOLA_RS00935 59fe6d8c75e5f253a0fd821d318a63d3 93 Pfam PF13616 PPIC-type PPIASE domain 14 90 3.3E-22 T 22-04-2016 TOLA_RS00935 59fe6d8c75e5f253a0fd821d318a63d3 93 PANTHER PTHR10657 4 92 6.7E-36 T 22-04-2016 TOLA_RS00935 59fe6d8c75e5f253a0fd821d318a63d3 93 Gene3D G3DSA:3.10.50.40 5 92 5.4E-34 T 22-04-2016 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 Gene3D G3DSA:1.10.10.350 363 461 1.1E-31 T 22-04-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 PANTHER PTHR11451 2 315 3.1E-107 T 22-04-2016 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 Gene3D G3DSA:3.90.800.10 68 180 1.0E-41 T 22-04-2016 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 3 461 34.956 T 22-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 Gene3D G3DSA:1.10.1160.10 233 315 1.2E-36 T 22-04-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 305 2.4E-119 T 22-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 SUPERFAMILY SSF52374 2 298 3.22E-115 T 22-04-2016 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 3.2E-27 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 3.2E-27 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 179 189 3.2E-27 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 3.2E-27 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 195 203 3.2E-27 T 22-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 SUPERFAMILY SSF48163 299 461 7.59E-45 T 22-04-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 PANTHER PTHR11451:SF41 2 315 3.1E-107 T 22-04-2016 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 459 5.4E-199 T 22-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 Gene3D G3DSA:3.40.50.620 2 67 2.9E-54 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS11975 4226622c1f9ae8611a466197d5e5b1aa 468 Gene3D G3DSA:3.40.50.620 181 230 2.9E-54 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS04995 2f1075f919956695e8565b024b63f0c3 172 TIGRFAM TIGR01752 flav_long: flavodoxin 2 168 6.8E-66 T 22-04-2016 IPR010086 Flavodoxin, long chain GO:0010181 TOLA_RS04995 2f1075f919956695e8565b024b63f0c3 172 PANTHER PTHR19384 1 119 1.8E-69 T 22-04-2016 TOLA_RS04995 2f1075f919956695e8565b024b63f0c3 172 PANTHER PTHR19384 141 170 1.8E-69 T 22-04-2016 TOLA_RS04995 2f1075f919956695e8565b024b63f0c3 172 SUPERFAMILY SSF52218 1 167 3.88E-46 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS04995 2f1075f919956695e8565b024b63f0c3 172 PIRSF PIRSF038996 1 171 1.6E-56 T 22-04-2016 IPR010086 Flavodoxin, long chain GO:0010181 TOLA_RS04995 2f1075f919956695e8565b024b63f0c3 172 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 22-04-2016 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 TOLA_RS04995 2f1075f919956695e8565b024b63f0c3 172 Gene3D G3DSA:3.40.50.360 1 168 2.3E-56 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS04995 2f1075f919956695e8565b024b63f0c3 172 Pfam PF00258 Flavodoxin 5 160 1.4E-25 T 22-04-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 TOLA_RS04995 2f1075f919956695e8565b024b63f0c3 172 PANTHER PTHR19384:SF73 1 119 1.8E-69 T 22-04-2016 TOLA_RS04995 2f1075f919956695e8565b024b63f0c3 172 PANTHER PTHR19384:SF73 141 170 1.8E-69 T 22-04-2016 TOLA_RS06605 81e0850f070a328afea82564f5a38733 162 PANTHER PTHR35458 1 156 2.8E-52 T 22-04-2016 TOLA_RS06605 81e0850f070a328afea82564f5a38733 162 Gene3D G3DSA:3.40.50.1010 1 153 6.1E-43 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS06605 81e0850f070a328afea82564f5a38733 162 Pfam PF01936 NYN domain 3 151 1.8E-37 T 22-04-2016 IPR021139 NYN domain, limkain-b1-type TOLA_RS06605 81e0850f070a328afea82564f5a38733 162 PANTHER PTHR35458:SF2 1 156 2.8E-52 T 22-04-2016 TOLA_RS06785 878d09d7cc71986e64f02a957b2eb8f5 215 PANTHER PTHR11732 1 210 2.8E-94 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta TOLA_RS06785 878d09d7cc71986e64f02a957b2eb8f5 215 PANTHER PTHR11732:SF269 1 210 2.8E-94 T 22-04-2016 TOLA_RS06785 878d09d7cc71986e64f02a957b2eb8f5 215 Gene3D G3DSA:3.20.20.100 1 70 1.7E-22 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS06785 878d09d7cc71986e64f02a957b2eb8f5 215 Pfam PF00248 Aldo/keto reductase family 70 203 7.0E-28 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS06785 878d09d7cc71986e64f02a957b2eb8f5 215 Pfam PF00248 Aldo/keto reductase family 16 80 2.1E-12 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS06785 878d09d7cc71986e64f02a957b2eb8f5 215 SUPERFAMILY SSF51430 1 207 6.74E-59 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS06785 878d09d7cc71986e64f02a957b2eb8f5 215 Gene3D G3DSA:3.20.20.100 71 210 1.2E-41 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS12865 16e4257e543c0db5eb4ff79abb78e2bf 417 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 52.675 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 TOLA_RS12865 16e4257e543c0db5eb4ff79abb78e2bf 417 PANTHER PTHR11680:SF9 1 416 0.0 T 22-04-2016 TOLA_RS12865 16e4257e543c0db5eb4ff79abb78e2bf 417 PANTHER PTHR11680 1 416 0.0 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 TOLA_RS12865 16e4257e543c0db5eb4ff79abb78e2bf 417 Gene3D G3DSA:3.40.640.10 37 285 5.3E-107 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS12865 16e4257e543c0db5eb4ff79abb78e2bf 417 SUPERFAMILY SSF53383 6 416 1.65E-180 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS12865 16e4257e543c0db5eb4ff79abb78e2bf 417 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 22-04-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 TOLA_RS12865 16e4257e543c0db5eb4ff79abb78e2bf 417 Pfam PF00464 Serine hydroxymethyltransferase 8 386 8.8E-182 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 TOLA_RS12865 16e4257e543c0db5eb4ff79abb78e2bf 417 Gene3D G3DSA:3.90.1150.10 286 416 4.7E-54 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS12865 16e4257e543c0db5eb4ff79abb78e2bf 417 PIRSF PIRSF000412 1 416 4.5E-169 T 22-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 SUPERFAMILY SSF53067 171 407 1.87E-68 T 22-04-2016 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 PANTHER PTHR21060:SF11 16 413 1.1E-128 T 22-04-2016 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 Pfam PF00871 Acetokinase family 16 400 9.0E-98 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 SUPERFAMILY SSF53067 16 207 7.77E-54 T 22-04-2016 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 PIRSF PIRSF000722 14 411 3.8E-123 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 PANTHER PTHR21060 16 413 1.1E-128 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 TIGRFAM TIGR00016 ackA: acetate kinase 16 403 1.9E-100 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 Gene3D G3DSA:3.30.420.40 84 216 1.6E-6 T 22-04-2016 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 Gene3D G3DSA:3.30.420.40 217 405 6.5E-63 T 22-04-2016 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 17 28 - T 22-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 PRINTS PR00471 Acetate kinase family signature 314 327 2.5E-33 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 PRINTS PR00471 Acetate kinase family signature 336 352 2.5E-33 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 PRINTS PR00471 Acetate kinase family signature 185 198 2.5E-33 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 PRINTS PR00471 Acetate kinase family signature 214 235 2.5E-33 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 PRINTS PR00471 Acetate kinase family signature 388 400 2.5E-33 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 PRINTS PR00471 Acetate kinase family signature 17 28 2.5E-33 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS12580 977bb93e3a40f201b30f81f4376dd2f2 413 Hamap MF_00020 Acetate kinase [ackA]. 1 410 139.785 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS02445 c2315a5b4fea0538b3ceb316642e1ea7 347 SUPERFAMILY SSF110997 269 338 1.31E-17 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 TOLA_RS02445 c2315a5b4fea0538b3ceb316642e1ea7 347 Gene3D G3DSA:3.30.70.1070 269 344 2.0E-22 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 TOLA_RS02445 c2315a5b4fea0538b3ceb316642e1ea7 347 Pfam PF05036 Sporulation related domain 270 337 9.7E-16 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 TOLA_RS04200 981da2713dc9cb67b2c8fa656271f527 194 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 5 191 2.9E-42 T 22-04-2016 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 TOLA_RS04200 981da2713dc9cb67b2c8fa656271f527 194 SUPERFAMILY SSF89392 18 191 1.65E-42 T 22-04-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX TOLA_RS04200 981da2713dc9cb67b2c8fa656271f527 194 PANTHER PTHR30634:SF11 8 192 3.8E-29 T 22-04-2016 TOLA_RS04200 981da2713dc9cb67b2c8fa656271f527 194 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 2 192 23.238 T 22-04-2016 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 TOLA_RS04200 981da2713dc9cb67b2c8fa656271f527 194 Gene3D G3DSA:2.50.20.10 11 192 3.4E-56 T 22-04-2016 TOLA_RS04200 981da2713dc9cb67b2c8fa656271f527 194 Pfam PF03550 Outer membrane lipoprotein LolB 43 190 1.9E-46 T 22-04-2016 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 TOLA_RS04200 981da2713dc9cb67b2c8fa656271f527 194 PANTHER PTHR30634 8 192 3.8E-29 T 22-04-2016 TOLA_RS13475 91020a41b91bb970e7b0a6d2f5f3a46e 175 PANTHER PTHR33269:SF2 1 172 1.4E-79 T 22-04-2016 TOLA_RS13475 91020a41b91bb970e7b0a6d2f5f3a46e 175 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 16 156 2.0E-32 T 22-04-2016 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 TOLA_RS13475 91020a41b91bb970e7b0a6d2f5f3a46e 175 PANTHER PTHR33269 1 172 1.4E-79 T 22-04-2016 TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 PANTHER PTHR11070 115 375 1.0E-88 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 PANTHER PTHR11070 545 878 1.0E-88 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 Pfam PF00580 UvrD/REP helicase N-terminal domain 214 661 3.5E-45 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 Gene3D G3DSA:3.40.91.30 385 438 1.5E-4 T 22-04-2016 IPR011578 Restriction endonuclease, FokI, C-terminal/endonuclease I, core GO:0003677|GO:0004536 TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 PANTHER PTHR11070:SF26 115 375 1.0E-88 T 22-04-2016 TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 PANTHER PTHR11070:SF26 545 878 1.0E-88 T 22-04-2016 TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 SUPERFAMILY SSF52540 555 865 1.42E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 SUPERFAMILY SSF52540 357 363 1.42E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 SUPERFAMILY SSF52540 212 330 1.42E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 Gene3D G3DSA:3.40.50.300 670 874 9.9E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 Pfam PF13361 UvrD-like helicase C-terminal domain 789 861 5.9E-16 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 957 983 2.1E-5 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 893 927 3.8E-4 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 Gene3D G3DSA:3.40.50.300 565 664 4.1E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06065 e5db5ea1ea750eadde6656e22d3ab838 1013 Gene3D G3DSA:3.40.50.300 212 351 4.1E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11985 ee8d6fd73856e6df8bdf9be4592879fc 242 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 68 229 5.7E-41 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS11985 ee8d6fd73856e6df8bdf9be4592879fc 242 PANTHER PTHR10799:SF710 105 231 3.7E-28 T 22-04-2016 TOLA_RS11985 ee8d6fd73856e6df8bdf9be4592879fc 242 PANTHER PTHR10799 105 231 3.7E-28 T 22-04-2016 TOLA_RS11985 ee8d6fd73856e6df8bdf9be4592879fc 242 Gene3D G3DSA:3.30.70.270 74 236 2.4E-48 T 22-04-2016 TOLA_RS11985 ee8d6fd73856e6df8bdf9be4592879fc 242 SMART SM00267 61 231 1.7E-53 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS11985 ee8d6fd73856e6df8bdf9be4592879fc 242 Pfam PF00990 Diguanylate cyclase, GGDEF domain 72 227 1.4E-42 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS11985 ee8d6fd73856e6df8bdf9be4592879fc 242 SUPERFAMILY SSF55073 77 233 6.43E-43 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS04220 b1e52a63717ae11e2d202ee78f329800 273 PANTHER PTHR31350 66 262 1.9E-27 T 22-04-2016 TOLA_RS04220 b1e52a63717ae11e2d202ee78f329800 273 Pfam PF13371 Tetratricopeptide repeat 191 263 6.1E-24 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS04220 b1e52a63717ae11e2d202ee78f329800 273 Pfam PF13369 Transglutaminase-like superfamily 42 188 8.1E-40 T 22-04-2016 IPR032698 Protein SirB1, N-terminal TOLA_RS04220 b1e52a63717ae11e2d202ee78f329800 273 PANTHER PTHR31350:SF1 66 262 1.9E-27 T 22-04-2016 TOLA_RS04220 b1e52a63717ae11e2d202ee78f329800 273 SUPERFAMILY SSF48452 194 260 2.74E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS04220 b1e52a63717ae11e2d202ee78f329800 273 Gene3D G3DSA:1.25.40.10 194 256 3.7E-6 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS00355 46dfe7f5d85da159e6d6da14448b42b3 469 Gene3D G3DSA:3.40.50.300 225 373 3.2E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00355 46dfe7f5d85da159e6d6da14448b42b3 469 SMART SM00487 32 229 2.3E-57 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS00355 46dfe7f5d85da159e6d6da14448b42b3 469 PANTHER PTHR24031:SF180 14 450 1.2E-237 T 22-04-2016 TOLA_RS00355 46dfe7f5d85da159e6d6da14448b42b3 469 PANTHER PTHR24031 14 450 1.2E-237 T 22-04-2016 TOLA_RS00355 46dfe7f5d85da159e6d6da14448b42b3 469 Pfam PF03880 DbpA RNA binding domain 396 466 6.3E-23 T 22-04-2016 IPR005580 DbpA, RNA-binding domain TOLA_RS00355 46dfe7f5d85da159e6d6da14448b42b3 469 SMART SM00490 266 347 7.1E-28 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS00355 46dfe7f5d85da159e6d6da14448b42b3 469 Pfam PF00271 Helicase conserved C-terminal domain 239 347 4.2E-26 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS00355 46dfe7f5d85da159e6d6da14448b42b3 469 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 161 169 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TOLA_RS00355 46dfe7f5d85da159e6d6da14448b42b3 469 Gene3D G3DSA:3.40.50.300 4 218 3.3E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00355 46dfe7f5d85da159e6d6da14448b42b3 469 SUPERFAMILY SSF52540 82 366 1.38E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00355 46dfe7f5d85da159e6d6da14448b42b3 469 Pfam PF00270 DEAD/DEAH box helicase 37 204 3.3E-45 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS15210 b934925a7eabf6510e4a593f2bf10a8b 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 22-04-2016 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15210 b934925a7eabf6510e4a593f2bf10a8b 115 SUPERFAMILY SSF50104 2 114 3.31E-47 T 22-04-2016 IPR008991 Translation protein SH3-like domain TOLA_RS15210 b934925a7eabf6510e4a593f2bf10a8b 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 31.39 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15210 b934925a7eabf6510e4a593f2bf10a8b 115 PIRSF PIRSF002191 1 115 1.6E-49 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15210 b934925a7eabf6510e4a593f2bf10a8b 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 1.6E-51 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15210 b934925a7eabf6510e4a593f2bf10a8b 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 1.1E-42 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15210 b934925a7eabf6510e4a593f2bf10a8b 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 1.1E-42 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15210 b934925a7eabf6510e4a593f2bf10a8b 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 1.1E-42 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15210 b934925a7eabf6510e4a593f2bf10a8b 115 PANTHER PTHR15680 1 114 8.3E-57 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15210 b934925a7eabf6510e4a593f2bf10a8b 115 Pfam PF01245 Ribosomal protein L19 3 113 1.4E-50 T 22-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 Pfam PF00224 Pyruvate kinase, barrel domain 1 340 6.4E-150 T 22-04-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 Gene3D G3DSA:3.40.1380.20 326 469 1.1E-43 T 22-04-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 SUPERFAMILY SSF50800 70 167 1.5E-28 T 22-04-2016 IPR011037 Pyruvate kinase-like, insert domain TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 PANTHER PTHR11817 1 464 5.8E-249 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 Gene3D G3DSA:2.40.33.10 73 168 1.1E-31 T 22-04-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 SUPERFAMILY SSF51621 1 74 3.45E-100 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 SUPERFAMILY SSF51621 156 338 3.45E-100 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 469 9.1E-188 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 468 5.7E-28 T 22-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 SUPERFAMILY SSF52935 324 469 2.75E-34 T 22-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 22-04-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 PRINTS PR01050 Pyruvate kinase family signature 269 293 1.2E-78 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 PRINTS PR01050 Pyruvate kinase family signature 59 75 1.2E-78 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 PRINTS PR01050 Pyruvate kinase family signature 186 200 1.2E-78 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 PRINTS PR01050 Pyruvate kinase family signature 244 268 1.2E-78 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 PRINTS PR01050 Pyruvate kinase family signature 294 312 1.2E-78 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 PRINTS PR01050 Pyruvate kinase family signature 217 243 1.2E-78 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 PRINTS PR01050 Pyruvate kinase family signature 313 329 1.2E-78 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 Gene3D G3DSA:3.20.20.60 169 325 6.1E-115 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS03110 6925a035a1571179fbca12af9842eb3d 470 Gene3D G3DSA:3.20.20.60 2 72 6.1E-115 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS03650 e9d6527e1a3a3176b4c0b2d3cac29bfc 276 Pfam PF00892 EamA-like transporter family 129 266 1.1E-6 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS03650 e9d6527e1a3a3176b4c0b2d3cac29bfc 276 SUPERFAMILY SSF103481 173 268 5.36E-6 T 22-04-2016 TOLA_RS03650 e9d6527e1a3a3176b4c0b2d3cac29bfc 276 PANTHER PTHR22911:SF27 1 274 1.3E-46 T 22-04-2016 TOLA_RS03650 e9d6527e1a3a3176b4c0b2d3cac29bfc 276 PANTHER PTHR22911 1 274 1.3E-46 T 22-04-2016 TOLA_RS10185 f79845f2c97f5418bb0fe82799c7fd73 425 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 266 378 8.5E-33 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal TOLA_RS10185 f79845f2c97f5418bb0fe82799c7fd73 425 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 420 5.7E-165 T 22-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 TOLA_RS10185 f79845f2c97f5418bb0fe82799c7fd73 425 SMART SM00825 Beta-ketoacyl synthase 6 424 3.2E-13 T 22-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TOLA_RS10185 f79845f2c97f5418bb0fe82799c7fd73 425 SUPERFAMILY SSF53901 225 422 2.23E-62 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS10185 f79845f2c97f5418bb0fe82799c7fd73 425 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 164 180 - T 22-04-2016 IPR018201 Beta-ketoacyl synthase, active site TOLA_RS10185 f79845f2c97f5418bb0fe82799c7fd73 425 PANTHER PTHR11712 1 423 8.5E-177 T 22-04-2016 TOLA_RS10185 f79845f2c97f5418bb0fe82799c7fd73 425 Gene3D G3DSA:3.40.47.10 274 423 2.4E-54 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS10185 f79845f2c97f5418bb0fe82799c7fd73 425 Gene3D G3DSA:3.40.47.10 4 267 6.3E-73 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS10185 f79845f2c97f5418bb0fe82799c7fd73 425 PIRSF PIRSF000447 1 424 4.5E-163 T 22-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 TOLA_RS10185 f79845f2c97f5418bb0fe82799c7fd73 425 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 257 1.1E-56 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal TOLA_RS10185 f79845f2c97f5418bb0fe82799c7fd73 425 SUPERFAMILY SSF53901 4 262 1.13E-73 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 SUPERFAMILY SSF55424 346 459 8.25E-20 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 1.9E-37 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 340 361 1.9E-37 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 304 311 1.9E-37 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.9E-37 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 151 1.9E-37 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 1.9E-37 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 260 274 1.9E-37 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 445 1.9E-37 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 1.9E-37 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 324 3.2E-33 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 5.8E-17 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 5.8E-17 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 275 5.8E-17 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 139 157 5.8E-17 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 Gene3D G3DSA:3.50.50.60 150 274 2.1E-16 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PANTHER PTHR22912:SF176 1 454 6.6E-88 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 450 9.4E-14 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 PANTHER PTHR22912 1 454 6.6E-88 T 22-04-2016 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 Gene3D G3DSA:3.30.390.30 348 459 1.3E-18 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 SUPERFAMILY SSF51905 99 333 4.32E-33 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 SUPERFAMILY SSF51905 1 63 4.32E-33 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 Gene3D G3DSA:3.50.50.60 275 335 3.8E-38 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS06185 c880dc84f7acacf5588da06440f40b47 474 Gene3D G3DSA:3.50.50.60 6 149 3.8E-38 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02290 2ddc3a02d7c5257b7eede84bf302bc14 347 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 59 267 2.4E-16 T 22-04-2016 IPR001761 Periplasmic binding protein/LacI sugar binding domain TOLA_RS02290 2ddc3a02d7c5257b7eede84bf302bc14 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 2.1E-18 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS02290 2ddc3a02d7c5257b7eede84bf302bc14 347 SMART SM00354 1 70 1.9E-31 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS02290 2ddc3a02d7c5257b7eede84bf302bc14 347 Gene3D G3DSA:3.40.50.2300 53 179 5.1E-24 T 22-04-2016 TOLA_RS02290 2ddc3a02d7c5257b7eede84bf302bc14 347 SUPERFAMILY SSF53822 60 322 4.93E-42 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS02290 2ddc3a02d7c5257b7eede84bf302bc14 347 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS02290 2ddc3a02d7c5257b7eede84bf302bc14 347 SUPERFAMILY SSF47413 1 58 4.44E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS02290 2ddc3a02d7c5257b7eede84bf302bc14 347 PANTHER PTHR30146 1 311 5.8E-70 T 22-04-2016 TOLA_RS02290 2ddc3a02d7c5257b7eede84bf302bc14 347 Gene3D G3DSA:1.10.260.40 2 52 2.6E-23 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS02290 2ddc3a02d7c5257b7eede84bf302bc14 347 Gene3D G3DSA:3.40.50.2300 180 311 7.9E-32 T 22-04-2016 TOLA_RS09390 7e32658b092eaa0ebf6e138618faf547 214 SUPERFAMILY SSF47413 2 61 4.83E-12 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS09390 7e32658b092eaa0ebf6e138618faf547 214 Gene3D G3DSA:2.10.109.10 118 212 2.2E-13 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain TOLA_RS09390 7e32658b092eaa0ebf6e138618faf547 214 SMART SM00530 2 53 2.9E-7 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS09390 7e32658b092eaa0ebf6e138618faf547 214 SUPERFAMILY SSF51306 119 213 8.89E-12 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C TOLA_RS09390 7e32658b092eaa0ebf6e138618faf547 214 Gene3D G3DSA:1.10.260.40 2 54 3.4E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS09390 7e32658b092eaa0ebf6e138618faf547 214 Pfam PF01381 Helix-turn-helix 2 53 1.8E-11 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS00870 88509c03450a762c57bf2de89be53a07 711 Pfam PF13489 Methyltransferase domain 495 664 2.5E-11 T 22-04-2016 TOLA_RS00870 88509c03450a762c57bf2de89be53a07 711 Gene3D G3DSA:3.40.50.150 476 676 5.0E-28 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS00870 88509c03450a762c57bf2de89be53a07 711 TIGRFAM TIGR04344 ovoA_Nterm: 5-histidylcysteine sulfoxide synthase 14 457 4.7E-206 T 22-04-2016 IPR027577 5-histidylcysteine sulfoxide synthase TOLA_RS00870 88509c03450a762c57bf2de89be53a07 711 PANTHER PTHR23150:SF24 1 494 8.2E-184 T 22-04-2016 TOLA_RS00870 88509c03450a762c57bf2de89be53a07 711 PANTHER PTHR23150 1 494 8.2E-184 T 22-04-2016 TOLA_RS00870 88509c03450a762c57bf2de89be53a07 711 SUPERFAMILY SSF53335 470 551 1.47E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS00870 88509c03450a762c57bf2de89be53a07 711 SUPERFAMILY SSF53335 582 670 1.47E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS00870 88509c03450a762c57bf2de89be53a07 711 Gene3D G3DSA:3.90.1580.10 194 461 7.9E-52 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme TOLA_RS00870 88509c03450a762c57bf2de89be53a07 711 Pfam PF12867 DinB superfamily 33 167 2.7E-10 T 22-04-2016 IPR024775 DinB-like domain TOLA_RS00870 88509c03450a762c57bf2de89be53a07 711 TIGRFAM TIGR04345 ovoA_Cterm: putative 4-mercaptohistidine N1-methyltranferase 470 710 1.5E-98 T 22-04-2016 IPR027625 Putative 4-mercaptohistidine N1-methyltranferase, OvoA C-terminal domain TOLA_RS00870 88509c03450a762c57bf2de89be53a07 711 SUPERFAMILY SSF56436 201 459 1.79E-54 T 22-04-2016 IPR016187 C-type lectin fold TOLA_RS00870 88509c03450a762c57bf2de89be53a07 711 Pfam PF03781 Sulfatase-modifying factor enzyme 1 203 457 4.1E-25 T 22-04-2016 IPR005532 Sulfatase-modifying factor enzyme TOLA_RS10225 df07970a25d31bb503a76562339877ac 274 PANTHER PTHR30035 18 273 5.4E-59 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 TOLA_RS10225 df07970a25d31bb503a76562339877ac 274 PANTHER PTHR30035:SF3 18 273 5.4E-59 T 22-04-2016 TOLA_RS10225 df07970a25d31bb503a76562339877ac 274 Pfam PF04333 MlaA lipoprotein 52 243 4.0E-62 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 TOLA_RS10225 df07970a25d31bb503a76562339877ac 274 PRINTS PR01805 VacJ lipoprotein signature 122 139 4.6E-17 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 TOLA_RS10225 df07970a25d31bb503a76562339877ac 274 PRINTS PR01805 VacJ lipoprotein signature 53 66 4.6E-17 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 TOLA_RS10225 df07970a25d31bb503a76562339877ac 274 PRINTS PR01805 VacJ lipoprotein signature 158 175 4.6E-17 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 TOLA_RS10225 df07970a25d31bb503a76562339877ac 274 PRINTS PR01805 VacJ lipoprotein signature 71 87 4.6E-17 T 22-04-2016 IPR007428 MlaA lipoprotein GO:0016020 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 Pfam PF02938 GAD domain 307 405 5.2E-31 T 22-04-2016 IPR029351 GAD domain TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 517 531 3.0E-26 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 473 489 3.0E-26 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 202 3.0E-26 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 3.0E-26 T 22-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 SUPERFAMILY SSF50249 1 105 2.48E-35 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 PANTHER PTHR22594 370 570 5.0E-254 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 PANTHER PTHR22594 1 296 5.0E-254 T 22-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 PANTHER PTHR22594:SF5 370 570 5.0E-254 T 22-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 PANTHER PTHR22594:SF5 1 296 5.0E-254 T 22-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 Pfam PF01336 OB-fold nucleic acid binding domain 18 102 7.1E-18 T 22-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 585 4.1E-267 T 22-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 1 562 37.175 T 22-04-2016 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 Gene3D G3DSA:3.30.1360.30 276 413 7.1E-49 T 22-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 SUPERFAMILY SSF55261 288 420 1.0E-46 T 22-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 SUPERFAMILY SSF55681 108 287 3.45E-107 T 22-04-2016 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 SUPERFAMILY SSF55681 419 581 3.45E-107 T 22-04-2016 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 Gene3D G3DSA:2.40.50.140 1 107 1.7E-39 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 557 9.3E-108 T 22-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 Gene3D G3DSA:3.30.930.10 131 275 1.6E-113 T 22-04-2016 TOLA_RS13855 cc44fc4a3b1d8d9ebb47a0b01537e168 588 Gene3D G3DSA:3.30.930.10 414 583 1.6E-113 T 22-04-2016 TOLA_RS00470 ee18df60422e56d238782de7af78eb3f 80 Pfam PF10678 Protein of unknown function (DUF2492) 3 79 1.7E-34 T 22-04-2016 IPR019620 Putative metal-binding protein TOLA_RS00470 ee18df60422e56d238782de7af78eb3f 80 TIGRFAM TIGR03853 matur_matur: putative metal-binding protein 4 80 6.5E-34 T 22-04-2016 IPR019620 Putative metal-binding protein TOLA_RS10640 7ef62beea161033aa3c4e78faa9bbe72 358 Pfam PF04055 Radical SAM superfamily 85 242 1.2E-15 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS10640 7ef62beea161033aa3c4e78faa9bbe72 358 PIRSF PIRSF004869 2 318 3.9E-92 T 22-04-2016 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted TOLA_RS10640 7ef62beea161033aa3c4e78faa9bbe72 358 PANTHER PTHR30352:SF5 5 344 5.7E-149 T 22-04-2016 TOLA_RS10640 7ef62beea161033aa3c4e78faa9bbe72 358 Gene3D G3DSA:3.80.30.10 126 292 7.6E-35 T 22-04-2016 TOLA_RS10640 7ef62beea161033aa3c4e78faa9bbe72 358 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 10 357 2.8E-187 T 22-04-2016 IPR027596 AmmeMemoRadiSam system radical SAM enzyme TOLA_RS10640 7ef62beea161033aa3c4e78faa9bbe72 358 SUPERFAMILY SSF102114 51 316 1.57E-38 T 22-04-2016 TOLA_RS10640 7ef62beea161033aa3c4e78faa9bbe72 358 PANTHER PTHR30352 5 344 5.7E-149 T 22-04-2016 TOLA_RS16145 3abdc6675df238966eb02d931f60be2c 388 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 9 381 3.3E-151 T 22-04-2016 IPR016633 Uncharacterised conserved protein UCP015557 TOLA_RS16145 3abdc6675df238966eb02d931f60be2c 388 PIRSF PIRSF015557 4 385 9.4E-155 T 22-04-2016 IPR016633 Uncharacterised conserved protein UCP015557 TOLA_RS16145 3abdc6675df238966eb02d931f60be2c 388 TIGRFAM TIGR03837 efp_adjacent_2: conserved hypothetical protein, PP_1857 family 9 381 5.6E-149 T 22-04-2016 IPR016633 Uncharacterised conserved protein UCP015557 TOLA_RS06900 f2294508f64d09db16268adf36077454 264 Gene3D G3DSA:3.40.50.300 7 234 7.9E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06900 f2294508f64d09db16268adf36077454 264 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS06900 f2294508f64d09db16268adf36077454 264 Pfam PF00005 ABC transporter 25 174 4.4E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS06900 f2294508f64d09db16268adf36077454 264 PANTHER PTHR24220:SF483 10 249 4.8E-131 T 22-04-2016 TOLA_RS06900 f2294508f64d09db16268adf36077454 264 PANTHER PTHR24220 10 249 4.8E-131 T 22-04-2016 TOLA_RS06900 f2294508f64d09db16268adf36077454 264 SUPERFAMILY SSF52540 7 234 2.0E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06900 f2294508f64d09db16268adf36077454 264 SMART SM00382 33 231 4.2E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 560 622 2.6E-12 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 Gene3D G3DSA:3.50.50.60 2 105 1.7E-26 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 633 757 2.4E-16 T 22-04-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PRINTS PR00397 Sirohaem Fe-binding site signature 636 654 4.0E-6 T 22-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PRINTS PR00397 Sirohaem Fe-binding site signature 679 697 4.0E-6 T 22-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 679 695 - T 22-04-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 Pfam PF04324 BFD-like [2Fe-2S] binding domain 424 471 1.3E-14 T 22-04-2016 IPR007419 BFD-like [2Fe-2S]-binding domain TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PIRSF PIRSF037149 1 835 0.0 T 22-04-2016 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 Gene3D G3DSA:3.50.50.60 106 310 1.1E-44 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 6 800 0.0 T 22-04-2016 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 UniPathway: UPA00653 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 SUPERFAMILY SSF51905 2 191 8.19E-41 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 304 8.5E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 SUPERFAMILY SSF55124 502 627 2.45E-32 T 22-04-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 2.4E-10 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 2.4E-10 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 236 250 2.4E-10 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 105 114 2.4E-10 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PANTHER PTHR11493:SF52 419 834 0.0 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PANTHER PTHR11493:SF52 2 257 0.0 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.8E-13 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 2.8E-13 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 2.8E-13 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 2.8E-13 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 2.8E-13 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 SUPERFAMILY SSF56014 633 809 5.59E-50 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 SUPERFAMILY SSF51905 143 311 9.07E-25 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 Gene3D G3DSA:3.30.413.10 634 768 1.0E-32 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PANTHER PTHR11493 419 834 0.0 T 22-04-2016 TOLA_RS02600 a756fa0d38cdbe06f56a3f5717e6f99e 849 PANTHER PTHR11493 2 257 0.0 T 22-04-2016 TOLA_RS10065 fc8c987a76295d7d74812828c74f5585 155 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 7.1E-59 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS10065 fc8c987a76295d7d74812828c74f5585 155 SUPERFAMILY SSF89623 1 144 1.7E-58 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS10065 fc8c987a76295d7d74812828c74f5585 155 Gene3D G3DSA:3.40.1400.10 1 147 3.4E-63 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS10065 fc8c987a76295d7d74812828c74f5585 155 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 144 4.0E-64 T 22-04-2016 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 TOLA_RS10065 fc8c987a76295d7d74812828c74f5585 155 Pfam PF02502 Ribose/Galactose Isomerase 3 140 1.1E-55 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS10065 fc8c987a76295d7d74812828c74f5585 155 PIRSF PIRSF005384 1 147 4.5E-59 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS10065 fc8c987a76295d7d74812828c74f5585 155 PANTHER PTHR30345 1 145 1.9E-75 T 22-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 TOLA_RS02530 220c9178e8921aca266e6d2652bf4d1c 302 PANTHER PTHR30537 1 302 1.7E-131 T 22-04-2016 TOLA_RS02530 220c9178e8921aca266e6d2652bf4d1c 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.7E-10 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS02530 220c9178e8921aca266e6d2652bf4d1c 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.7E-10 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS02530 220c9178e8921aca266e6d2652bf4d1c 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.7E-10 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS02530 220c9178e8921aca266e6d2652bf4d1c 302 PANTHER PTHR30537:SF26 1 302 1.7E-131 T 22-04-2016 TOLA_RS02530 220c9178e8921aca266e6d2652bf4d1c 302 Pfam PF03466 LysR substrate binding domain 91 289 1.5E-34 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS02530 220c9178e8921aca266e6d2652bf4d1c 302 SUPERFAMILY SSF53850 93 294 2.53E-36 T 22-04-2016 TOLA_RS02530 220c9178e8921aca266e6d2652bf4d1c 302 Gene3D G3DSA:3.40.190.10 180 260 3.6E-24 T 22-04-2016 TOLA_RS02530 220c9178e8921aca266e6d2652bf4d1c 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.1E-20 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS02530 220c9178e8921aca266e6d2652bf4d1c 302 Gene3D G3DSA:1.10.10.10 1 86 6.4E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02530 220c9178e8921aca266e6d2652bf4d1c 302 SUPERFAMILY SSF46785 3 85 1.19E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02530 220c9178e8921aca266e6d2652bf4d1c 302 Gene3D G3DSA:3.40.190.10 94 179 7.8E-31 T 22-04-2016 TOLA_RS15690 ddca82d5e49c1762719e0ef5e36d8121 475 PRINTS PR00113 Alkaline phosphatase signature 188 198 1.1E-43 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS15690 ddca82d5e49c1762719e0ef5e36d8121 475 PRINTS PR00113 Alkaline phosphatase signature 86 101 1.1E-43 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS15690 ddca82d5e49c1762719e0ef5e36d8121 475 PRINTS PR00113 Alkaline phosphatase signature 36 56 1.1E-43 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS15690 ddca82d5e49c1762719e0ef5e36d8121 475 PRINTS PR00113 Alkaline phosphatase signature 134 154 1.1E-43 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS15690 ddca82d5e49c1762719e0ef5e36d8121 475 PRINTS PR00113 Alkaline phosphatase signature 268 297 1.1E-43 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS15690 ddca82d5e49c1762719e0ef5e36d8121 475 Gene3D G3DSA:3.40.720.10 28 475 2.2E-141 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 TOLA_RS15690 ddca82d5e49c1762719e0ef5e36d8121 475 SMART SM00098 37 475 6.9E-95 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS15690 ddca82d5e49c1762719e0ef5e36d8121 475 Pfam PF00245 Alkaline phosphatase 37 474 8.3E-102 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS15690 ddca82d5e49c1762719e0ef5e36d8121 475 PANTHER PTHR11596 36 475 2.8E-148 T 22-04-2016 TOLA_RS15690 ddca82d5e49c1762719e0ef5e36d8121 475 SUPERFAMILY SSF53649 31 475 1.04E-125 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 TOLA_RS04515 72b917d3e947f330734e2db1c62e0cec 248 ProSitePatterns PS01087 Radical activating enzymes signature. 18 39 - T 22-04-2016 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 TOLA_RS04515 72b917d3e947f330734e2db1c62e0cec 248 PANTHER PTHR30352 1 248 6.4E-132 T 22-04-2016 TOLA_RS04515 72b917d3e947f330734e2db1c62e0cec 248 SUPERFAMILY SSF102114 23 220 3.53E-25 T 22-04-2016 TOLA_RS04515 72b917d3e947f330734e2db1c62e0cec 248 Gene3D G3DSA:3.80.30.10 69 246 1.9E-65 T 22-04-2016 TOLA_RS04515 72b917d3e947f330734e2db1c62e0cec 248 PANTHER PTHR30352:SF9 1 248 6.4E-132 T 22-04-2016 TOLA_RS04515 72b917d3e947f330734e2db1c62e0cec 248 Pfam PF13353 4Fe-4S single cluster domain 16 137 3.7E-19 T 22-04-2016 TOLA_RS04515 72b917d3e947f330734e2db1c62e0cec 248 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 6 240 4.5E-101 T 22-04-2016 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 TOLA_RS04515 72b917d3e947f330734e2db1c62e0cec 248 Pfam PF04055 Radical SAM superfamily 26 179 1.8E-29 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS16155 06771a6be4d3f4a1f9b916cb512bb4f5 356 Pfam PF01594 Domain of unknown function DUF20 15 345 1.1E-34 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like TOLA_RS16155 06771a6be4d3f4a1f9b916cb512bb4f5 356 PANTHER PTHR21716:SF20 4 351 9.3E-60 T 22-04-2016 TOLA_RS16155 06771a6be4d3f4a1f9b916cb512bb4f5 356 PANTHER PTHR21716 4 351 9.3E-60 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like TOLA_RS00900 288dc08540b0c1f161221505742f3c7b 220 Pfam PF13417 Glutathione S-transferase, N-terminal domain 12 82 1.3E-13 T 22-04-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TOLA_RS00900 288dc08540b0c1f161221505742f3c7b 220 SUPERFAMILY SSF52833 6 82 2.29E-18 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS00900 288dc08540b0c1f161221505742f3c7b 220 PANTHER PTHR11260:SF144 5 197 6.2E-55 T 22-04-2016 TOLA_RS00900 288dc08540b0c1f161221505742f3c7b 220 PANTHER PTHR11260 5 197 6.2E-55 T 22-04-2016 TOLA_RS00900 288dc08540b0c1f161221505742f3c7b 220 Gene3D G3DSA:3.40.30.10 12 82 1.1E-17 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS00900 288dc08540b0c1f161221505742f3c7b 220 SUPERFAMILY SSF47616 84 204 2.32E-14 T 22-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like TOLA_RS00900 288dc08540b0c1f161221505742f3c7b 220 Gene3D G3DSA:1.20.1050.10 87 207 8.5E-45 T 22-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like TOLA_RS14200 5daaf781fb4f92ab51ea575ad6e48041 153 ProSitePatterns PS01335 Methylglyoxal synthase active site. 66 74 - T 22-04-2016 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TOLA_RS14200 5daaf781fb4f92ab51ea575ad6e48041 153 PANTHER PTHR30492 3 151 8.0E-81 T 22-04-2016 TOLA_RS14200 5daaf781fb4f92ab51ea575ad6e48041 153 PIRSF PIRSF006614 9 152 1.7E-64 T 22-04-2016 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TOLA_RS14200 5daaf781fb4f92ab51ea575ad6e48041 153 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 13 132 36.823 T 22-04-2016 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TOLA_RS14200 5daaf781fb4f92ab51ea575ad6e48041 153 Pfam PF02142 MGS-like domain 27 119 2.4E-19 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain TOLA_RS14200 5daaf781fb4f92ab51ea575ad6e48041 153 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 12 152 2.6E-62 T 22-04-2016 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TOLA_RS14200 5daaf781fb4f92ab51ea575ad6e48041 153 SMART SM00851 26 119 3.0E-27 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain TOLA_RS14200 5daaf781fb4f92ab51ea575ad6e48041 153 SUPERFAMILY SSF52335 7 148 3.66E-55 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain TOLA_RS14200 5daaf781fb4f92ab51ea575ad6e48041 153 Gene3D G3DSA:3.40.50.1380 6 152 1.6E-63 T 22-04-2016 IPR011607 Methylglyoxal synthase-like domain TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 Gene3D G3DSA:1.20.1080.10 7 252 9.7E-77 T 22-04-2016 IPR023271 Aquaporin-like TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 PANTHER PTHR19139 10 252 2.7E-74 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 PANTHER PTHR19139:SF100 10 252 2.7E-74 T 22-04-2016 TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 SUPERFAMILY SSF81338 7 252 6.02E-72 T 22-04-2016 IPR023271 Aquaporin-like TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 PRINTS PR00783 Major intrinsic protein family signature 151 169 1.2E-47 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 PRINTS PR00783 Major intrinsic protein family signature 48 72 1.2E-47 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 PRINTS PR00783 Major intrinsic protein family signature 9 28 1.2E-47 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 PRINTS PR00783 Major intrinsic protein family signature 184 206 1.2E-47 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 PRINTS PR00783 Major intrinsic protein family signature 85 104 1.2E-47 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 PRINTS PR00783 Major intrinsic protein family signature 234 253 1.2E-47 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 ProSitePatterns PS00221 MIP family signature. 66 74 - T 22-04-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 Pfam PF00230 Major intrinsic protein 7 251 5.8E-60 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS09625 b1275aaa846bedc8c769e1d7a4fa0fe0 253 TIGRFAM TIGR00861 MIP: MIP family channel proteins 13 251 1.3E-62 T 22-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS09235 81265f1b5c506ba91ee4a60195e24a8b 104 Pfam PF15731 Antitoxin component of bacterial toxin-antitoxin system, MqsA 18 101 9.1E-9 T 22-04-2016 IPR032758 Antitoxin MqsA/igA-2 TOLA_RS09235 81265f1b5c506ba91ee4a60195e24a8b 104 PANTHER PTHR36511 1 102 3.0E-44 T 22-04-2016 TOLA_RS09235 81265f1b5c506ba91ee4a60195e24a8b 104 PANTHER PTHR36511:SF3 1 102 3.0E-44 T 22-04-2016 TOLA_RS09235 81265f1b5c506ba91ee4a60195e24a8b 104 Gene3D G3DSA:1.10.260.40 44 96 1.0E-16 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS09235 81265f1b5c506ba91ee4a60195e24a8b 104 SUPERFAMILY SSF47413 43 90 4.5E-8 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS03560 29b5a730d4b6ece4722495791f109f0c 131 PANTHER PTHR33337:SF11 1 131 7.1E-41 T 22-04-2016 TOLA_RS03560 29b5a730d4b6ece4722495791f109f0c 131 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 24 112 8.7E-25 T 22-04-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 TOLA_RS03560 29b5a730d4b6ece4722495791f109f0c 131 SUPERFAMILY SSF51316 1 131 5.34E-50 T 22-04-2016 IPR011057 Mss4-like TOLA_RS03560 29b5a730d4b6ece4722495791f109f0c 131 PANTHER PTHR33337 1 131 7.1E-41 T 22-04-2016 TOLA_RS03560 29b5a730d4b6ece4722495791f109f0c 131 Gene3D G3DSA:3.90.1590.10 2 130 1.1E-45 T 22-04-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 TOLA_RS00295 3229f3c32ab841023da790e94961a596 333 PANTHER PTHR32196:SF21 1 329 2.9E-113 T 22-04-2016 TOLA_RS00295 3229f3c32ab841023da790e94961a596 333 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 320 3.2E-43 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS00295 3229f3c32ab841023da790e94961a596 333 PANTHER PTHR32196 1 329 2.9E-113 T 22-04-2016 TOLA_RS06570 94293e59eb31e87e71b990b492fbeae6 627 SUPERFAMILY SSF51621 121 215 1.81E-64 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS06570 94293e59eb31e87e71b990b492fbeae6 627 SUPERFAMILY SSF51621 439 613 1.81E-64 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS06570 94293e59eb31e87e71b990b492fbeae6 627 Gene3D G3DSA:3.20.20.60 142 214 3.2E-65 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS06570 94293e59eb31e87e71b990b492fbeae6 627 Gene3D G3DSA:3.20.20.60 440 604 3.2E-65 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS06570 94293e59eb31e87e71b990b492fbeae6 627 SUPERFAMILY SSF50800 364 439 2.09E-10 T 22-04-2016 IPR011037 Pyruvate kinase-like, insert domain TOLA_RS06570 94293e59eb31e87e71b990b492fbeae6 627 Gene3D G3DSA:2.40.33.10 373 439 4.7E-15 T 22-04-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS06570 94293e59eb31e87e71b990b492fbeae6 627 PANTHER PTHR11817:SF28 36 221 3.2E-162 T 22-04-2016 TOLA_RS06570 94293e59eb31e87e71b990b492fbeae6 627 PANTHER PTHR11817:SF28 339 620 3.2E-162 T 22-04-2016 TOLA_RS06570 94293e59eb31e87e71b990b492fbeae6 627 Pfam PF00224 Pyruvate kinase, barrel domain 142 227 2.6E-10 T 22-04-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS06570 94293e59eb31e87e71b990b492fbeae6 627 Pfam PF00224 Pyruvate kinase, barrel domain 370 608 2.8E-38 T 22-04-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS06570 94293e59eb31e87e71b990b492fbeae6 627 PANTHER PTHR11817 36 221 3.2E-162 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS06570 94293e59eb31e87e71b990b492fbeae6 627 PANTHER PTHR11817 339 620 3.2E-162 T 22-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 TOLA_RS07140 32e8f25eb092afb23dc972474fec0155 231 Pfam PF00849 RNA pseudouridylate synthase 63 193 2.2E-16 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS07140 32e8f25eb092afb23dc972474fec0155 231 SMART SM00363 1 62 1.2E-5 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS07140 32e8f25eb092afb23dc972474fec0155 231 PANTHER PTHR21600:SF19 1 229 5.1E-66 T 22-04-2016 TOLA_RS07140 32e8f25eb092afb23dc972474fec0155 231 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 224 4.8E-47 T 22-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 TOLA_RS07140 32e8f25eb092afb23dc972474fec0155 231 SUPERFAMILY SSF55120 63 228 1.6E-42 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS07140 32e8f25eb092afb23dc972474fec0155 231 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 22-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 TOLA_RS07140 32e8f25eb092afb23dc972474fec0155 231 SUPERFAMILY SSF55174 1 89 4.58E-14 T 22-04-2016 TOLA_RS07140 32e8f25eb092afb23dc972474fec0155 231 Gene3D G3DSA:3.10.290.10 1 63 1.1E-17 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS07140 32e8f25eb092afb23dc972474fec0155 231 PANTHER PTHR21600 1 229 5.1E-66 T 22-04-2016 TOLA_RS07140 32e8f25eb092afb23dc972474fec0155 231 Pfam PF01479 S4 domain 1 46 5.4E-7 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS05965 d36b9e0c8f619ede28ae45fe1ef68099 832 Gene3D G3DSA:3.40.50.300 281 408 4.1E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05965 d36b9e0c8f619ede28ae45fe1ef68099 832 Gene3D G3DSA:1.10.3680.10 10 115 9.7E-9 T 22-04-2016 IPR029024 TerB-like TOLA_RS05965 d36b9e0c8f619ede28ae45fe1ef68099 832 Pfam PF01926 50S ribosome-binding GTPase 282 388 7.3E-11 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS05965 d36b9e0c8f619ede28ae45fe1ef68099 832 SUPERFAMILY SSF52540 254 461 1.12E-17 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05965 d36b9e0c8f619ede28ae45fe1ef68099 832 SUPERFAMILY SSF158682 11 126 7.72E-11 T 22-04-2016 IPR029024 TerB-like TOLA_RS05965 d36b9e0c8f619ede28ae45fe1ef68099 832 Gene3D G3DSA:3.20.20.70 140 264 3.4E-4 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS06805 4c158821a1d542c7056c61dc12fa7e42 283 SUPERFAMILY SSF51430 2 260 1.01E-87 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS06805 4c158821a1d542c7056c61dc12fa7e42 283 Gene3D G3DSA:3.20.20.100 2 263 6.4E-97 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS06805 4c158821a1d542c7056c61dc12fa7e42 283 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 120 137 - T 22-04-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TOLA_RS06805 4c158821a1d542c7056c61dc12fa7e42 283 PRINTS PR00069 Aldo-keto reductase signature 154 183 3.4E-44 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS06805 4c158821a1d542c7056c61dc12fa7e42 283 PRINTS PR00069 Aldo-keto reductase signature 120 137 3.4E-44 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS06805 4c158821a1d542c7056c61dc12fa7e42 283 PRINTS PR00069 Aldo-keto reductase signature 91 109 3.4E-44 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS06805 4c158821a1d542c7056c61dc12fa7e42 283 PRINTS PR00069 Aldo-keto reductase signature 35 59 3.4E-44 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS06805 4c158821a1d542c7056c61dc12fa7e42 283 PRINTS PR00069 Aldo-keto reductase signature 193 217 3.4E-44 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS06805 4c158821a1d542c7056c61dc12fa7e42 283 PANTHER PTHR11732:SF236 1 283 2.8E-145 T 22-04-2016 TOLA_RS06805 4c158821a1d542c7056c61dc12fa7e42 283 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 22-04-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TOLA_RS06805 4c158821a1d542c7056c61dc12fa7e42 283 PANTHER PTHR11732 1 283 2.8E-145 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta TOLA_RS06805 4c158821a1d542c7056c61dc12fa7e42 283 Pfam PF00248 Aldo/keto reductase family 15 256 5.4E-46 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 PANTHER PTHR11533 603 863 0.0 T 22-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 PANTHER PTHR11533 13 582 0.0 T 22-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 SUPERFAMILY SSF55486 204 449 1.67E-72 T 22-04-2016 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 Pfam PF01433 Peptidase family M1 22 383 1.3E-68 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 Gene3D G3DSA:1.10.390.10 307 450 1.3E-33 T 22-04-2016 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 PANTHER PTHR11533:SF152 603 863 0.0 T 22-04-2016 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 PANTHER PTHR11533:SF152 13 582 0.0 T 22-04-2016 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 Pfam PF11940 Domain of unknown function (DUF3458) 458 821 5.8E-123 T 22-04-2016 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 257 267 5.7E-9 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 125 140 5.7E-9 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 293 308 5.7E-9 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 312 324 5.7E-9 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 175 190 5.7E-9 T 22-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 863 0.0 T 22-04-2016 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 Gene3D G3DSA:1.25.50.10 540 864 2.7E-112 T 22-04-2016 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal TOLA_RS07870 aa66148298931291f729abb485b7b8fb 865 SUPERFAMILY SSF63737 7 192 1.83E-44 T 22-04-2016 TOLA_RS08655 69c5a4f64517e976b747f5c2f67f58ac 142 Gene3D G3DSA:3.40.50.300 3 141 7.8E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08655 69c5a4f64517e976b747f5c2f67f58ac 142 SUPERFAMILY SSF52540 3 141 2.39E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08655 69c5a4f64517e976b747f5c2f67f58ac 142 PANTHER PTHR40453:SF1 2 141 1.7E-28 T 22-04-2016 TOLA_RS08655 69c5a4f64517e976b747f5c2f67f58ac 142 TIGRFAM TIGR02528 EutP: ethanolamine utilization protein, EutP 2 142 1.3E-54 T 22-04-2016 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 TOLA_RS08655 69c5a4f64517e976b747f5c2f67f58ac 142 PIRSF PIRSF036409 1 142 2.0E-53 T 22-04-2016 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 TOLA_RS08655 69c5a4f64517e976b747f5c2f67f58ac 142 PANTHER PTHR40453 2 141 1.7E-28 T 22-04-2016 TOLA_RS08655 69c5a4f64517e976b747f5c2f67f58ac 142 Pfam PF10662 Ethanolamine utilisation - propanediol utilisation 1 142 4.8E-56 T 22-04-2016 IPR012381 Ethanolamine/propanediol utilisation protein, EutP/PduV GO:0005524|GO:0006576 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 SUPERFAMILY SSF46548 2 154 1.06E-40 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 469 1.5E-27 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 Gene3D G3DSA:3.50.50.60 248 411 8.2E-42 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 Gene3D G3DSA:3.40.50.720 415 486 5.0E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 Gene3D G3DSA:3.40.50.720 147 247 5.0E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 PANTHER PTHR11938 346 481 3.4E-135 T 22-04-2016 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 PANTHER PTHR11938 38 330 3.4E-135 T 22-04-2016 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 PANTHER PTHR11938:SF75 346 481 3.4E-135 T 22-04-2016 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 PANTHER PTHR11938:SF75 38 330 3.4E-135 T 22-04-2016 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 131 5.2E-26 T 22-04-2016 IPR028261 Dihydroprymidine dehydrogenase domain II TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 SUPERFAMILY SSF51971 382 482 3.41E-11 T 22-04-2016 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 487 4.3E-212 T 22-04-2016 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 Gene3D G3DSA:1.10.1060.10 3 146 4.4E-42 T 22-04-2016 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 SUPERFAMILY SSF51971 142 411 1.65E-66 T 22-04-2016 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 PRINTS PR00419 Adrenodoxin reductase family signature 297 311 1.0E-20 T 22-04-2016 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 1.0E-20 T 22-04-2016 TOLA_RS02520 2e9f1f7784916cb9a0aa6986fc42a6b3 488 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 1.0E-20 T 22-04-2016 TOLA_RS13505 2cf38bea3f4e7323c650e983f0e8770b 385 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 262 282 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS13505 2cf38bea3f4e7323c650e983f0e8770b 385 Gene3D G3DSA:3.40.50.1970 1 182 5.5E-58 T 22-04-2016 TOLA_RS13505 2cf38bea3f4e7323c650e983f0e8770b 385 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 365 9.5E-94 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 TOLA_RS13505 2cf38bea3f4e7323c650e983f0e8770b 385 PANTHER PTHR11496 1 385 9.1E-210 T 22-04-2016 TOLA_RS13505 2cf38bea3f4e7323c650e983f0e8770b 385 Gene3D G3DSA:1.20.1090.10 183 384 1.3E-52 T 22-04-2016 TOLA_RS13505 2cf38bea3f4e7323c650e983f0e8770b 385 PANTHER PTHR11496:SF65 1 385 9.1E-210 T 22-04-2016 TOLA_RS13505 2cf38bea3f4e7323c650e983f0e8770b 385 SUPERFAMILY SSF56796 1 382 1.57E-110 T 22-04-2016 TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 SUPERFAMILY SSF46785 2 87 2.34E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 Gene3D G3DSA:1.10.10.10 1 87 1.7E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 PANTHER PTHR30118 1 309 3.2E-100 T 22-04-2016 TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 PANTHER PTHR30118:SF4 1 309 3.2E-100 T 22-04-2016 TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 Pfam PF03466 LysR substrate binding domain 97 298 2.0E-23 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.7E-16 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 Gene3D G3DSA:3.40.190.10 275 303 5.2E-24 T 22-04-2016 TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 Gene3D G3DSA:3.40.190.10 90 175 5.2E-24 T 22-04-2016 TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 Gene3D G3DSA:3.40.190.10 176 271 9.3E-24 T 22-04-2016 TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 SUPERFAMILY SSF53850 90 298 2.9E-38 T 22-04-2016 TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.1E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.1E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS02470 884161e9a8d5574461ade61523d7565e 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.1E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS02780 e0f3caaf89180a83b9f9398e033f09d6 568 SUPERFAMILY SSF160246 6 141 2.88E-30 T 22-04-2016 TOLA_RS02780 e0f3caaf89180a83b9f9398e033f09d6 568 SUPERFAMILY SSF52540 168 566 9.24E-105 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02780 e0f3caaf89180a83b9f9398e033f09d6 568 Gene3D G3DSA:3.30.450.90 165 291 1.2E-51 T 22-04-2016 TOLA_RS02780 e0f3caaf89180a83b9f9398e033f09d6 568 PANTHER PTHR30258 1 566 6.1E-252 T 22-04-2016 TOLA_RS02780 e0f3caaf89180a83b9f9398e033f09d6 568 Gene3D G3DSA:3.40.50.300 298 566 7.6E-100 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02780 e0f3caaf89180a83b9f9398e033f09d6 568 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 41 143 7.1E-16 T 22-04-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 TOLA_RS02780 e0f3caaf89180a83b9f9398e033f09d6 568 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 8 566 3.1E-260 T 22-04-2016 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 TOLA_RS02780 e0f3caaf89180a83b9f9398e033f09d6 568 Pfam PF00437 Type II/IV secretion system protein 192 458 1.4E-87 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 TOLA_RS02780 e0f3caaf89180a83b9f9398e033f09d6 568 PANTHER PTHR30258:SF1 1 566 6.1E-252 T 22-04-2016 TOLA_RS02780 e0f3caaf89180a83b9f9398e033f09d6 568 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 386 400 - T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 TOLA_RS05825 684acc32a1bcc544a2fb14262e1f108b 324 SUPERFAMILY SSF53850 88 320 2.61E-42 T 22-04-2016 TOLA_RS05825 684acc32a1bcc544a2fb14262e1f108b 324 SUPERFAMILY SSF46785 1 88 6.12E-14 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05825 684acc32a1bcc544a2fb14262e1f108b 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.4E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS05825 684acc32a1bcc544a2fb14262e1f108b 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.4E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS05825 684acc32a1bcc544a2fb14262e1f108b 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.4E-8 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS05825 684acc32a1bcc544a2fb14262e1f108b 324 PANTHER PTHR30126 1 309 6.3E-209 T 22-04-2016 TOLA_RS05825 684acc32a1bcc544a2fb14262e1f108b 324 Gene3D G3DSA:1.10.10.10 1 81 3.0E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05825 684acc32a1bcc544a2fb14262e1f108b 324 Gene3D G3DSA:3.40.190.10 185 260 1.5E-28 T 22-04-2016 TOLA_RS05825 684acc32a1bcc544a2fb14262e1f108b 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 1.0E-15 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS05825 684acc32a1bcc544a2fb14262e1f108b 324 Pfam PF03466 LysR substrate binding domain 90 292 4.4E-39 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS05825 684acc32a1bcc544a2fb14262e1f108b 324 PANTHER PTHR30126:SF6 1 309 6.3E-209 T 22-04-2016 TOLA_RS05825 684acc32a1bcc544a2fb14262e1f108b 324 Gene3D G3DSA:3.40.190.10 91 184 6.7E-21 T 22-04-2016 TOLA_RS14785 5f7327c569613ae14e8ccc0869469ec0 788 PANTHER PTHR22762 8 781 4.1E-260 T 22-04-2016 TOLA_RS14785 5f7327c569613ae14e8ccc0869469ec0 788 SUPERFAMILY SSF74650 3 243 8.16E-45 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 TOLA_RS14785 5f7327c569613ae14e8ccc0869469ec0 788 Pfam PF01055 Glycosyl hydrolases family 31 238 683 5.6E-121 T 22-04-2016 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 TOLA_RS14785 5f7327c569613ae14e8ccc0869469ec0 788 SUPERFAMILY SSF51011 597 678 4.82E-20 T 22-04-2016 TOLA_RS14785 5f7327c569613ae14e8ccc0869469ec0 788 Pfam PF13802 Galactose mutarotase-like 147 213 1.7E-22 T 22-04-2016 IPR025887 Glycoside hydrolase family 31, N-terminal domain TOLA_RS14785 5f7327c569613ae14e8ccc0869469ec0 788 Pfam PF17137 Domain of unknown function (DUF5110) 700 767 3.2E-6 T 22-04-2016 IPR033403 Domain of unknown function DUF5110 TOLA_RS14785 5f7327c569613ae14e8ccc0869469ec0 788 PANTHER PTHR22762:SF7 8 781 4.1E-260 T 22-04-2016 TOLA_RS14785 5f7327c569613ae14e8ccc0869469ec0 788 SUPERFAMILY SSF51445 247 593 8.96E-72 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS10530 fdee7cfb46b527123c4fc865ed8716df 302 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 301 40.874 T 22-04-2016 IPR007476 Putative exonuclease, RdgC GO:0006310 TOLA_RS10530 fdee7cfb46b527123c4fc865ed8716df 302 PANTHER PTHR38103 2 302 1.1E-144 T 22-04-2016 TOLA_RS10530 fdee7cfb46b527123c4fc865ed8716df 302 Pfam PF04381 Putative exonuclease, RdgC 1 299 1.3E-129 T 22-04-2016 IPR007476 Putative exonuclease, RdgC GO:0006310 TOLA_RS10530 fdee7cfb46b527123c4fc865ed8716df 302 PANTHER PTHR38103:SF1 2 302 1.1E-144 T 22-04-2016 TOLA_RS00455 5eb4977dd18e427a91604d3ad1bd3b16 85 Pfam PF06667 Phage shock protein B 4 75 4.0E-27 T 22-04-2016 IPR009554 Phage shock protein B GO:0006355|GO:0009271 TOLA_RS00455 5eb4977dd18e427a91604d3ad1bd3b16 85 TIGRFAM TIGR02976 phageshock_pspB: phage shock protein B 4 75 1.1E-22 T 22-04-2016 IPR009554 Phage shock protein B GO:0006355|GO:0009271 TOLA_RS14345 b089d6b043240c9d65d048bd8656c9d7 148 Pfam PF00583 Acetyltransferase (GNAT) family 49 122 2.5E-13 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS14345 b089d6b043240c9d65d048bd8656c9d7 148 Gene3D G3DSA:3.40.630.30 1 146 7.4E-28 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS14345 b089d6b043240c9d65d048bd8656c9d7 148 SUPERFAMILY SSF55729 1 145 1.38E-27 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS14345 b089d6b043240c9d65d048bd8656c9d7 148 PANTHER PTHR23091 1 145 6.1E-26 T 22-04-2016 TOLA_RS14345 b089d6b043240c9d65d048bd8656c9d7 148 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 12 143 6.2E-37 T 22-04-2016 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 TOLA_RS14345 b089d6b043240c9d65d048bd8656c9d7 148 PANTHER PTHR23091:SF247 1 145 6.1E-26 T 22-04-2016 TOLA_RS15090 8105ab22da017e9f9abcd26f62d4f51a 91 Pfam PF00381 PTS HPr component phosphorylation site 5 84 9.8E-22 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS15090 8105ab22da017e9f9abcd26f62d4f51a 91 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 41 56 - T 22-04-2016 IPR002114 Phosphotransferase system, HPr serine phosphorylation site TOLA_RS15090 8105ab22da017e9f9abcd26f62d4f51a 91 Gene3D G3DSA:3.30.1340.10 4 89 3.4E-26 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS15090 8105ab22da017e9f9abcd26f62d4f51a 91 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 5 84 1.1E-22 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS15090 8105ab22da017e9f9abcd26f62d4f51a 91 PANTHER PTHR33705 1 91 4.4E-36 T 22-04-2016 TOLA_RS15090 8105ab22da017e9f9abcd26f62d4f51a 91 SUPERFAMILY SSF55594 5 90 3.14E-25 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS15090 8105ab22da017e9f9abcd26f62d4f51a 91 PRINTS PR00107 Phosphocarrier protein signature 55 72 3.3E-9 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS15090 8105ab22da017e9f9abcd26f62d4f51a 91 PRINTS PR00107 Phosphocarrier protein signature 15 31 3.3E-9 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS15090 8105ab22da017e9f9abcd26f62d4f51a 91 PRINTS PR00107 Phosphocarrier protein signature 40 55 3.3E-9 T 22-04-2016 IPR000032 Phosphocarrier HPr protein-like TOLA_RS15090 8105ab22da017e9f9abcd26f62d4f51a 91 PANTHER PTHR33705:SF2 1 91 4.4E-36 T 22-04-2016 TOLA_RS04375 0fd14f5786a5bb7da5dbb624cf7eabef 243 PANTHER PTHR30456 2 243 3.4E-145 T 22-04-2016 TOLA_RS04375 0fd14f5786a5bb7da5dbb624cf7eabef 243 SUPERFAMILY SSF63892 4 242 8.5E-101 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 TOLA_RS04375 0fd14f5786a5bb7da5dbb624cf7eabef 243 Gene3D G3DSA:3.20.20.70 3 242 2.4E-110 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS04375 0fd14f5786a5bb7da5dbb624cf7eabef 243 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 6 239 7.2E-103 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 TOLA_RS04375 0fd14f5786a5bb7da5dbb624cf7eabef 243 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 6 238 1.6E-103 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 TOLA_RS04375 0fd14f5786a5bb7da5dbb624cf7eabef 243 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 243 131.286 T 22-04-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 TOLA_RS04375 0fd14f5786a5bb7da5dbb624cf7eabef 243 PANTHER PTHR30456:SF0 2 243 3.4E-145 T 22-04-2016 TOLA_RS02515 652d972b25d263613ef006e68aa9f8eb 128 SUPERFAMILY SSF55729 33 121 8.83E-10 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS02515 652d972b25d263613ef006e68aa9f8eb 128 Gene3D G3DSA:3.40.630.30 33 121 6.9E-9 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS02515 652d972b25d263613ef006e68aa9f8eb 128 Pfam PF12568 Acetyltransferase (GNAT) domain 35 124 1.2E-12 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS09685 5615f360682a78f4e670f8481c9f85a1 255 Gene3D G3DSA:2.60.120.620 15 235 6.9E-27 T 22-04-2016 TOLA_RS09685 5615f360682a78f4e670f8481c9f85a1 255 PANTHER PTHR20883:SF0 14 242 7.2E-15 T 22-04-2016 TOLA_RS09685 5615f360682a78f4e670f8481c9f85a1 255 PANTHER PTHR20883 14 242 7.2E-15 T 22-04-2016 TOLA_RS09685 5615f360682a78f4e670f8481c9f85a1 255 SUPERFAMILY SSF51197 16 251 1.1E-42 T 22-04-2016 TOLA_RS09685 5615f360682a78f4e670f8481c9f85a1 255 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 27 216 3.6E-22 T 22-04-2016 IPR008775 Phytanoyl-CoA dioxygenase TOLA_RS13830 19d70e9a493ef3991380a1079184d2a5 518 PANTHER PTHR30365:SF0 378 518 4.8E-260 T 22-04-2016 TOLA_RS13830 19d70e9a493ef3991380a1079184d2a5 518 PANTHER PTHR30365:SF0 1 312 4.8E-260 T 22-04-2016 TOLA_RS13830 19d70e9a493ef3991380a1079184d2a5 518 PIRSF PIRSF006446 3 517 6.4E-150 T 22-04-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 TOLA_RS13830 19d70e9a493ef3991380a1079184d2a5 518 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 503 1.1E-178 T 22-04-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 TOLA_RS13830 19d70e9a493ef3991380a1079184d2a5 518 PANTHER PTHR30365 378 518 4.8E-260 T 22-04-2016 TOLA_RS13830 19d70e9a493ef3991380a1079184d2a5 518 PANTHER PTHR30365 1 312 4.8E-260 T 22-04-2016 TOLA_RS05210 0196e980da71f44796d455119cf313af 421 Gene3D G3DSA:3.40.190.10 312 350 3.7E-33 T 22-04-2016 TOLA_RS05210 0196e980da71f44796d455119cf313af 421 Gene3D G3DSA:3.40.190.10 23 137 3.7E-33 T 22-04-2016 TOLA_RS05210 0196e980da71f44796d455119cf313af 421 Pfam PF13416 Bacterial extracellular solute-binding protein 43 344 4.3E-27 T 22-04-2016 TOLA_RS05210 0196e980da71f44796d455119cf313af 421 Gene3D G3DSA:3.40.190.10 138 311 5.4E-10 T 22-04-2016 TOLA_RS05210 0196e980da71f44796d455119cf313af 421 SUPERFAMILY SSF53850 23 407 1.01E-56 T 22-04-2016 TOLA_RS05210 0196e980da71f44796d455119cf313af 421 PANTHER PTHR30061 5 412 1.2E-40 T 22-04-2016 TOLA_RS07925 3a6dc1384d379e792691b17c88222e31 385 Pfam PF13432 Tetratricopeptide repeat 111 164 0.002 T 22-04-2016 TOLA_RS07925 3a6dc1384d379e792691b17c88222e31 385 Gene3D G3DSA:1.25.40.10 39 245 1.1E-21 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS07925 3a6dc1384d379e792691b17c88222e31 385 Gene3D G3DSA:1.25.40.10 279 331 1.1E-21 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS07925 3a6dc1384d379e792691b17c88222e31 385 Pfam PF13176 Tetratricopeptide repeat 71 94 0.017 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS07925 3a6dc1384d379e792691b17c88222e31 385 PANTHER PTHR23083 296 334 2.5E-22 T 22-04-2016 TOLA_RS07925 3a6dc1384d379e792691b17c88222e31 385 PANTHER PTHR23083 8 263 2.5E-22 T 22-04-2016 TOLA_RS07925 3a6dc1384d379e792691b17c88222e31 385 SMART SM00028 177 210 96.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS07925 3a6dc1384d379e792691b17c88222e31 385 SMART SM00028 211 244 3.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS07925 3a6dc1384d379e792691b17c88222e31 385 SMART SM00028 69 102 66.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS07925 3a6dc1384d379e792691b17c88222e31 385 Pfam PF14559 Tetratricopeptide repeat 190 255 7.8E-12 T 22-04-2016 TOLA_RS07925 3a6dc1384d379e792691b17c88222e31 385 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 4 383 34.39 T 22-04-2016 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 TOLA_RS07925 3a6dc1384d379e792691b17c88222e31 385 SUPERFAMILY SSF81901 40 246 9.68E-16 T 22-04-2016 TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 Gene3D G3DSA:2.60.40.10 9 151 1.7E-30 T 22-04-2016 IPR013783 Immunoglobulin-like fold TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 SUPERFAMILY SSF51445 496 564 1.36E-127 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 SUPERFAMILY SSF51445 133 467 1.36E-127 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 SUPERFAMILY SSF81296 9 147 3.85E-27 T 22-04-2016 IPR014756 Immunoglobulin E-set TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 PANTHER PTHR10357:SF74 5 571 4.0E-275 T 22-04-2016 TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 PANTHER PTHR10357:SF74 588 685 4.0E-275 T 22-04-2016 TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 Pfam PF00128 Alpha amylase, catalytic domain 178 271 4.7E-16 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 SMART SM00642 158 555 2.6E-16 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 Gene3D G3DSA:2.60.40.1180 584 685 2.0E-16 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 SUPERFAMILY SSF51011 585 685 2.16E-16 T 22-04-2016 TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 PANTHER PTHR10357 5 571 4.0E-275 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 PANTHER PTHR10357 588 685 4.0E-275 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 9 650 2.3E-195 T 22-04-2016 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 UniPathway: UPA00165 TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 13 104 2.5E-9 T 22-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 TOLA_RS05325 2e40bc8e9a9eaebe7f65c50f79fe6d54 690 Gene3D G3DSA:3.20.20.80 152 565 6.3E-121 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS10240 9a6f43d2413ed616afb39e322eab3dd6 112 PRINTS PR00355 Adrenodoxin signature 60 74 6.2E-10 T 22-04-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 TOLA_RS10240 9a6f43d2413ed616afb39e322eab3dd6 112 PRINTS PR00355 Adrenodoxin signature 83 91 6.2E-10 T 22-04-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 TOLA_RS10240 9a6f43d2413ed616afb39e322eab3dd6 112 PRINTS PR00355 Adrenodoxin signature 42 52 6.2E-10 T 22-04-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 TOLA_RS10240 9a6f43d2413ed616afb39e322eab3dd6 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 91 4.6E-14 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TOLA_RS10240 9a6f43d2413ed616afb39e322eab3dd6 112 SUPERFAMILY SSF54292 4 105 1.66E-33 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TOLA_RS10240 9a6f43d2413ed616afb39e322eab3dd6 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 110 2.0E-60 T 22-04-2016 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 TOLA_RS10240 9a6f43d2413ed616afb39e322eab3dd6 112 PANTHER PTHR23426 7 112 2.8E-42 T 22-04-2016 TOLA_RS10240 9a6f43d2413ed616afb39e322eab3dd6 112 Gene3D G3DSA:3.10.20.30 5 108 6.6E-35 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS10240 9a6f43d2413ed616afb39e322eab3dd6 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 22-04-2016 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 TOLA_RS11245 ab6333c76ae99bae46bb3b90f97b40f0 200 Gene3D G3DSA:3.40.50.140 82 171 8.5E-4 T 22-04-2016 IPR006171 Toprim domain TOLA_RS11245 ab6333c76ae99bae46bb3b90f97b40f0 200 Pfam PF13662 Toprim domain 82 172 2.7E-23 T 22-04-2016 IPR006171 Toprim domain TOLA_RS11245 ab6333c76ae99bae46bb3b90f97b40f0 200 TIGRFAM TIGR00615 recR: recombination protein RecR 2 197 7.8E-74 T 22-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TOLA_RS11245 ab6333c76ae99bae46bb3b90f97b40f0 200 SMART SM00493 81 166 1.6E-16 T 22-04-2016 IPR006171 Toprim domain TOLA_RS11245 ab6333c76ae99bae46bb3b90f97b40f0 200 SUPERFAMILY SSF111304 2 199 9.15E-71 T 22-04-2016 IPR023627 Recombination protein RecR TOLA_RS11245 ab6333c76ae99bae46bb3b90f97b40f0 200 Pfam PF02132 RecR protein 41 77 3.6E-13 T 22-04-2016 IPR023628 Recombination protein RecR, C4-type zinc finger TOLA_RS11245 ab6333c76ae99bae46bb3b90f97b40f0 200 PANTHER PTHR30446 1 200 5.7E-111 T 22-04-2016 TOLA_RS11245 ab6333c76ae99bae46bb3b90f97b40f0 200 PANTHER PTHR30446:SF0 1 200 5.7E-111 T 22-04-2016 TOLA_RS11245 ab6333c76ae99bae46bb3b90f97b40f0 200 Hamap MF_00017 Recombination protein RecR [recR]. 1 199 96.1 T 22-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TOLA_RS08330 2995ddabd5d7fc2d2acaf31f30bb30c2 311 Pfam PF00892 EamA-like transporter family 165 300 7.7E-17 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS08330 2995ddabd5d7fc2d2acaf31f30bb30c2 311 Pfam PF00892 EamA-like transporter family 26 152 1.3E-17 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS08330 2995ddabd5d7fc2d2acaf31f30bb30c2 311 PANTHER PTHR12715:SF4 26 297 3.5E-44 T 22-04-2016 TOLA_RS08330 2995ddabd5d7fc2d2acaf31f30bb30c2 311 SUPERFAMILY SSF103481 53 155 5.1E-9 T 22-04-2016 TOLA_RS08330 2995ddabd5d7fc2d2acaf31f30bb30c2 311 SUPERFAMILY SSF103481 199 303 1.31E-7 T 22-04-2016 TOLA_RS08330 2995ddabd5d7fc2d2acaf31f30bb30c2 311 PANTHER PTHR12715 26 297 3.5E-44 T 22-04-2016 TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 PANTHER PTHR24321 2 252 1.6E-56 T 22-04-2016 TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 PANTHER PTHR24321:SF6 2 252 1.6E-56 T 22-04-2016 TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 Gene3D G3DSA:3.40.50.720 1 252 1.4E-91 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.8E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 3.8E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.8E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.8E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.8E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.8E-42 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 251 2.8E-73 T 22-04-2016 TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 SUPERFAMILY SSF51735 5 252 2.8E-87 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.9E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.9E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS06340 75c940e47c5863a2d971cffbcb6f2014 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.9E-10 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS07005 c1b735a42d4247b101220942c08385f5 333 Pfam PF02608 Basic membrane protein 32 323 3.5E-63 T 22-04-2016 IPR003760 Basic membrane lipoprotein GO:0005886 TOLA_RS07005 c1b735a42d4247b101220942c08385f5 333 PANTHER PTHR34296:SF2 4 322 8.4E-102 T 22-04-2016 TOLA_RS07005 c1b735a42d4247b101220942c08385f5 333 SUPERFAMILY SSF53822 41 267 6.02E-19 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS07005 c1b735a42d4247b101220942c08385f5 333 Gene3D G3DSA:3.40.50.2300 48 142 8.0E-4 T 22-04-2016 TOLA_RS07005 c1b735a42d4247b101220942c08385f5 333 Gene3D G3DSA:3.40.50.2300 143 292 8.5E-60 T 22-04-2016 TOLA_RS07005 c1b735a42d4247b101220942c08385f5 333 PANTHER PTHR34296 4 322 8.4E-102 T 22-04-2016 TOLA_RS02125 a628dc7f69d72d2728a523ae9056a501 450 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 95 106 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS02125 a628dc7f69d72d2728a523ae9056a501 450 Pfam PF13183 4Fe-4S dicluster domain 35 109 2.9E-9 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TOLA_RS02125 a628dc7f69d72d2728a523ae9056a501 450 Gene3D G3DSA:1.10.1060.10 32 117 5.6E-10 T 22-04-2016 TOLA_RS02125 a628dc7f69d72d2728a523ae9056a501 450 SUPERFAMILY SSF46548 33 113 3.14E-6 T 22-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 TOLA_RS09290 10dca5c62f4bfe6377b2981036e49f95 472 SUPERFAMILY SSF53743 4 325 3.66E-63 T 22-04-2016 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 TOLA_RS09290 10dca5c62f4bfe6377b2981036e49f95 472 PANTHER PTHR36120 5 471 3.3E-217 T 22-04-2016 TOLA_RS09290 10dca5c62f4bfe6377b2981036e49f95 472 Pfam PF02952 L-fucose isomerase, C-terminal domain 343 471 1.2E-35 T 22-04-2016 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25|UniPathway: UPA00563 TOLA_RS09290 10dca5c62f4bfe6377b2981036e49f95 472 PANTHER PTHR36120:SF1 5 471 3.3E-217 T 22-04-2016 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 PANTHER PTHR11070 784 1158 0.0 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 PANTHER PTHR11070 5 87 0.0 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 PANTHER PTHR11070 509 767 0.0 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 PANTHER PTHR11070 116 213 0.0 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 PANTHER PTHR11070 295 483 0.0 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 2 1163 14.753 T 22-04-2016 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 Gene3D G3DSA:1.10.486.10 575 720 1.4E-47 T 22-04-2016 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 Pfam PF13361 UvrD-like helicase C-terminal domain 720 798 1.0E-10 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 PANTHER PTHR11070:SF23 784 1158 0.0 T 22-04-2016 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 PANTHER PTHR11070:SF23 5 87 0.0 T 22-04-2016 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 PANTHER PTHR11070:SF23 509 767 0.0 T 22-04-2016 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 PANTHER PTHR11070:SF23 116 213 0.0 T 22-04-2016 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 PANTHER PTHR11070:SF23 295 483 0.0 T 22-04-2016 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 Pfam PF00580 UvrD/REP helicase N-terminal domain 12 432 7.2E-62 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 Gene3D G3DSA:3.40.50.300 721 859 1.1E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 Gene3D G3DSA:3.40.50.300 445 572 1.1E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 SUPERFAMILY SSF52540 514 803 5.32E-103 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 SUPERFAMILY SSF52540 320 465 5.32E-103 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 SUPERFAMILY SSF52540 116 200 5.32E-103 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 SUPERFAMILY SSF52540 8 78 5.32E-103 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 Gene3D G3DSA:3.90.320.10 880 1166 1.9E-97 T 22-04-2016 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 Gene3D G3DSA:1.10.3170.10 154 343 6.6E-52 T 22-04-2016 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 Gene3D G3DSA:3.40.50.300 118 148 3.6E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 Gene3D G3DSA:3.40.50.300 9 80 3.6E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 Gene3D G3DSA:3.40.50.300 346 444 3.6E-50 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 SUPERFAMILY SSF52980 889 1164 2.52E-85 T 22-04-2016 IPR011335 Restriction endonuclease type II-like TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 5 1162 0.0 T 22-04-2016 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 TOLA_RS00325 e4ac8700fa3ee049fb45bc7fec606f0f 1175 Pfam PF12705 PD-(D/E)XK nuclease superfamily 936 1134 6.2E-7 T 22-04-2016 TOLA_RS02595 92a1f041669686f3649124442aa168dd 109 SUPERFAMILY SSF50022 1 106 3.93E-35 T 22-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TOLA_RS02595 92a1f041669686f3649124442aa168dd 109 Gene3D G3DSA:2.102.10.10 1 106 2.0E-38 T 22-04-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TOLA_RS02595 92a1f041669686f3649124442aa168dd 109 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 2 106 1.4E-34 T 22-04-2016 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 TOLA_RS02595 92a1f041669686f3649124442aa168dd 109 PANTHER PTHR40562 3 109 6.2E-49 T 22-04-2016 TOLA_RS02595 92a1f041669686f3649124442aa168dd 109 Pfam PF13806 Rieske-like [2Fe-2S] domain 2 105 3.8E-38 T 22-04-2016 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 TOLA_RS13650 3a632c886a9842fdfa8bcf26b6db40c6 251 Pfam PF01695 IstB-like ATP binding protein 54 229 2.6E-59 T 22-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 TOLA_RS13650 3a632c886a9842fdfa8bcf26b6db40c6 251 PANTHER PTHR30050 8 240 1.0E-66 T 22-04-2016 TOLA_RS13650 3a632c886a9842fdfa8bcf26b6db40c6 251 Pfam PF08483 IstB-like ATP binding N-terminal 24 52 1.2E-10 T 22-04-2016 IPR013690 IstB-like ATP binding N-terminal TOLA_RS13650 3a632c886a9842fdfa8bcf26b6db40c6 251 PANTHER PTHR30050:SF6 8 240 1.0E-66 T 22-04-2016 TOLA_RS13650 3a632c886a9842fdfa8bcf26b6db40c6 251 Gene3D G3DSA:3.40.50.300 52 230 3.9E-29 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13650 3a632c886a9842fdfa8bcf26b6db40c6 251 SUPERFAMILY SSF52540 65 239 6.05E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13650 3a632c886a9842fdfa8bcf26b6db40c6 251 PIRSF PIRSF003073 2 250 4.7E-70 T 22-04-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein TOLA_RS11365 6f352ca0d3722f182d44f28499504895 227 Gene3D G3DSA:3.40.50.300 4 223 3.2E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11365 6f352ca0d3722f182d44f28499504895 227 SMART SM00382 34 222 8.7E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS11365 6f352ca0d3722f182d44f28499504895 227 PANTHER PTHR24220:SF111 7 223 1.5E-114 T 22-04-2016 TOLA_RS11365 6f352ca0d3722f182d44f28499504895 227 PANTHER PTHR24220 7 223 1.5E-114 T 22-04-2016 TOLA_RS11365 6f352ca0d3722f182d44f28499504895 227 Pfam PF00005 ABC transporter 25 173 6.8E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS11365 6f352ca0d3722f182d44f28499504895 227 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 5 223 1.6E-99 T 22-04-2016 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0006810|GO:0016020 TOLA_RS11365 6f352ca0d3722f182d44f28499504895 227 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS11365 6f352ca0d3722f182d44f28499504895 227 SUPERFAMILY SSF52540 5 223 2.34E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01245 b39d15396db5e10491b3279c2639d514 295 PANTHER PTHR12715:SF5 9 295 8.3E-70 T 22-04-2016 TOLA_RS01245 b39d15396db5e10491b3279c2639d514 295 SUPERFAMILY SSF103481 44 146 7.85E-12 T 22-04-2016 TOLA_RS01245 b39d15396db5e10491b3279c2639d514 295 PANTHER PTHR12715 9 295 8.3E-70 T 22-04-2016 TOLA_RS01245 b39d15396db5e10491b3279c2639d514 295 Pfam PF00892 EamA-like transporter family 155 290 1.9E-16 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS01245 b39d15396db5e10491b3279c2639d514 295 Pfam PF00892 EamA-like transporter family 8 144 9.6E-12 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS01245 b39d15396db5e10491b3279c2639d514 295 SUPERFAMILY SSF103481 194 293 2.09E-13 T 22-04-2016 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 280 334 - T 22-04-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 2.2E-95 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 2.2E-95 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 2.2E-95 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 2.2E-95 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 2.2E-95 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 2.2E-95 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 2.2E-95 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 2.2E-95 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 2.2E-95 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 2.2E-95 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 2.2E-95 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 2.2E-95 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 Gene3D G3DSA:1.20.210.10 38 589 2.1E-189 T 22-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 647 0.0 T 22-04-2016 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PANTHER PTHR10422:SF26 33 614 0.0 T 22-04-2016 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 PANTHER PTHR10422 33 614 0.0 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 503 2.9E-136 T 22-04-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS10595 d4d990785658ec41d3574d7a39c0a156 663 SUPERFAMILY SSF81442 43 559 4.45E-180 T 22-04-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 TOLA_RS13220 7e98c20de58173011a362c48ce3ac776 256 PANTHER PTHR10889 1 254 7.3E-108 T 22-04-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 TOLA_RS13220 7e98c20de58173011a362c48ce3ac776 256 PIRSF PIRSF001357 5 252 7.9E-75 T 22-04-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 TOLA_RS13220 7e98c20de58173011a362c48ce3ac776 256 Pfam PF01791 DeoC/LacD family aldolase 11 241 4.0E-39 T 22-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 TOLA_RS13220 7e98c20de58173011a362c48ce3ac776 256 Gene3D G3DSA:3.20.20.70 5 249 7.7E-90 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS13220 7e98c20de58173011a362c48ce3ac776 256 SMART SM01133 10 243 1.4E-77 T 22-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 TOLA_RS13220 7e98c20de58173011a362c48ce3ac776 256 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 11 225 4.0E-71 T 22-04-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 TOLA_RS13220 7e98c20de58173011a362c48ce3ac776 256 SUPERFAMILY SSF51569 7 243 1.78E-79 T 22-04-2016 TOLA_RS05660 b7608dc04d3cb40223c56a444bc471f0 425 Gene3D G3DSA:3.90.1150.10 303 424 1.2E-40 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS05660 b7608dc04d3cb40223c56a444bc471f0 425 PANTHER PTHR11986 1 424 2.5E-189 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS05660 b7608dc04d3cb40223c56a444bc471f0 425 Pfam PF00202 Aminotransferase class-III 14 421 5.1E-131 T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS05660 b7608dc04d3cb40223c56a444bc471f0 425 SUPERFAMILY SSF53383 20 424 1.61E-133 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS05660 b7608dc04d3cb40223c56a444bc471f0 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 22-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TOLA_RS05660 b7608dc04d3cb40223c56a444bc471f0 425 PANTHER PTHR11986:SF70 1 424 2.5E-189 T 22-04-2016 TOLA_RS05660 b7608dc04d3cb40223c56a444bc471f0 425 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 8 421 1.1E-168 T 22-04-2016 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 TOLA_RS05660 b7608dc04d3cb40223c56a444bc471f0 425 Gene3D G3DSA:3.40.640.10 58 302 1.8E-85 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS08095 6db702650dfc32707fe859dbc31c5a81 671 SUPERFAMILY SSF52540 400 628 8.63E-9 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08095 6db702650dfc32707fe859dbc31c5a81 671 SUPERFAMILY SSF52540 1 353 2.93E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08095 6db702650dfc32707fe859dbc31c5a81 671 TIGRFAM TIGR03185 DNA_S_dndD: DNA sulfur modification protein DndD 1 662 1.3E-148 T 22-04-2016 IPR017599 DNA sulphur modification protein DndD TOLA_RS08095 6db702650dfc32707fe859dbc31c5a81 671 Pfam PF13476 AAA domain 5 296 3.9E-14 T 22-04-2016 TOLA_RS08095 6db702650dfc32707fe859dbc31c5a81 671 Gene3D G3DSA:3.40.50.300 1 134 9.5E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10410 b055a8168eb9bfb375629d544aec6f9b 242 PANTHER PTHR22916:SF4 2 240 1.2E-46 T 22-04-2016 TOLA_RS10410 b055a8168eb9bfb375629d544aec6f9b 242 Pfam PF00535 Glycosyl transferase family 2 6 119 4.2E-22 T 22-04-2016 IPR001173 Glycosyltransferase 2-like TOLA_RS10410 b055a8168eb9bfb375629d544aec6f9b 242 SUPERFAMILY SSF53448 3 203 5.94E-35 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS10410 b055a8168eb9bfb375629d544aec6f9b 242 PANTHER PTHR22916 2 240 1.2E-46 T 22-04-2016 TOLA_RS10410 b055a8168eb9bfb375629d544aec6f9b 242 Gene3D G3DSA:3.90.550.10 1 138 8.9E-29 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS06050 76ef2bfad6c20d1fc478a4f85b738f72 659 Pfam PF03235 Protein of unknown function DUF262 11 213 5.8E-31 T 22-04-2016 IPR004919 Domain of unknown function DUF262 TOLA_RS06050 76ef2bfad6c20d1fc478a4f85b738f72 659 Pfam PF07510 Protein of unknown function (DUF1524) 528 650 2.4E-13 T 22-04-2016 IPR011089 Domain of unknown function DUF1524 TOLA_RS06050 76ef2bfad6c20d1fc478a4f85b738f72 659 ProDom PD062361 VC1766 YFJM PM0595 580 659 7.0E-13 T 22-04-2016 TOLA_RS06050 76ef2bfad6c20d1fc478a4f85b738f72 659 PANTHER PTHR35149:SF2 1 223 2.6E-27 T 22-04-2016 TOLA_RS06050 76ef2bfad6c20d1fc478a4f85b738f72 659 PANTHER PTHR35149 1 223 2.6E-27 T 22-04-2016 TOLA_RS12705 5ddd03b9284cd4f3260926e2c1358866 305 Pfam PF03547 Membrane transport protein 158 298 1.3E-18 T 22-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 TOLA_RS12705 5ddd03b9284cd4f3260926e2c1358866 305 Pfam PF03547 Membrane transport protein 11 144 5.9E-8 T 22-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 TOLA_RS12705 5ddd03b9284cd4f3260926e2c1358866 305 PANTHER PTHR36838:SF1 6 305 2.3E-45 T 22-04-2016 TOLA_RS12705 5ddd03b9284cd4f3260926e2c1358866 305 PANTHER PTHR36838 6 305 2.3E-45 T 22-04-2016 TOLA_RS01290 e96bc31dc08261b3a9f08c9a784fe3d1 327 TIGRFAM TIGR00825 EIIBC-GUT: PTS system, glucitol/sorbitol-specific, IIBC component 4 327 4.2E-165 T 22-04-2016 IPR004702 Phosphotransferease, sorbitol phosphotransferase enzyme II GO:0008982|GO:0009401|GO:0016021 TOLA_RS01290 e96bc31dc08261b3a9f08c9a784fe3d1 327 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 234 326 2.8E-45 T 22-04-2016 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 TOLA_RS01290 e96bc31dc08261b3a9f08c9a784fe3d1 327 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 5 179 2.8E-74 T 22-04-2016 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 TOLA_RS01290 e96bc31dc08261b3a9f08c9a784fe3d1 327 PANTHER PTHR39427 1 327 2.8E-117 T 22-04-2016 TOLA_RS00315 d356e1f5bf294b2b6f48e32146e7637a 307 SUPERFAMILY SSF141523 93 149 1.44E-28 T 22-04-2016 TOLA_RS00315 d356e1f5bf294b2b6f48e32146e7637a 307 SUPERFAMILY SSF141523 177 233 1.44E-28 T 22-04-2016 TOLA_RS00315 d356e1f5bf294b2b6f48e32146e7637a 307 Gene3D G3DSA:2.40.440.10 92 234 3.5E-35 T 22-04-2016 TOLA_RS00315 d356e1f5bf294b2b6f48e32146e7637a 307 Gene3D G3DSA:3.10.350.10 53 88 3.3E-5 T 22-04-2016 IPR018392 LysM domain TOLA_RS00315 d356e1f5bf294b2b6f48e32146e7637a 307 Pfam PF03734 L,D-transpeptidase catalytic domain 100 231 1.6E-18 T 22-04-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 TOLA_RS00315 d356e1f5bf294b2b6f48e32146e7637a 307 Pfam PF01476 LysM domain 53 88 7.3E-5 T 22-04-2016 IPR018392 LysM domain TOLA_RS00315 d356e1f5bf294b2b6f48e32146e7637a 307 PANTHER PTHR30582:SF8 1 306 1.1E-131 T 22-04-2016 TOLA_RS00315 d356e1f5bf294b2b6f48e32146e7637a 307 PANTHER PTHR30582 1 306 1.1E-131 T 22-04-2016 TOLA_RS09710 e320abdc8e37a21ba1b6539332200b64 298 Pfam PF08668 HDOD domain 137 194 1.5E-5 T 22-04-2016 IPR013976 Metal-dependent hydrolase HDOD TOLA_RS09710 e320abdc8e37a21ba1b6539332200b64 298 Gene3D G3DSA:1.10.3210.10 147 257 5.7E-8 T 22-04-2016 IPR006674 HD domain TOLA_RS09710 e320abdc8e37a21ba1b6539332200b64 298 SUPERFAMILY SSF109604 137 257 7.18E-12 T 22-04-2016 TOLA_RS09710 e320abdc8e37a21ba1b6539332200b64 298 SMART SM00471 143 227 0.0066 T 22-04-2016 IPR003607 HD/PDEase domain TOLA_RS14235 8f751bf40952e30194a529a30313c0a6 130 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 4 130 7.1E-48 T 22-04-2016 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 TOLA_RS14235 8f751bf40952e30194a529a30313c0a6 130 Pfam PF02635 DsrE/DsrF-like family 5 130 1.0E-26 T 22-04-2016 IPR003787 Sulphur relay, DsrE/F-like protein TOLA_RS14235 8f751bf40952e30194a529a30313c0a6 130 PANTHER PTHR34874 3 130 1.2E-45 T 22-04-2016 TOLA_RS14235 8f751bf40952e30194a529a30313c0a6 130 SUPERFAMILY SSF75169 1 130 4.12E-34 T 22-04-2016 IPR027396 DsrEFH-like TOLA_RS14235 8f751bf40952e30194a529a30313c0a6 130 PANTHER PTHR34874:SF1 3 130 1.2E-45 T 22-04-2016 TOLA_RS14235 8f751bf40952e30194a529a30313c0a6 130 Gene3D G3DSA:3.40.1260.10 5 130 8.3E-26 T 22-04-2016 IPR027396 DsrEFH-like TOLA_RS11140 b92c368f2634cd543c4b3b9612929f07 318 Gene3D G3DSA:3.40.47.10 3 160 1.2E-61 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS11140 b92c368f2634cd543c4b3b9612929f07 318 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 2 318 7.4E-139 T 22-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 TOLA_RS11140 b92c368f2634cd543c4b3b9612929f07 318 Gene3D G3DSA:3.40.47.10 161 317 1.3E-50 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS11140 b92c368f2634cd543c4b3b9612929f07 318 PANTHER PTHR18919 26 318 1.1E-125 T 22-04-2016 TOLA_RS11140 b92c368f2634cd543c4b3b9612929f07 318 SUPERFAMILY SSF53901 3 318 8.73E-69 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS11140 b92c368f2634cd543c4b3b9612929f07 318 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 229 318 9.7E-35 T 22-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 TOLA_RS11140 b92c368f2634cd543c4b3b9612929f07 318 PANTHER PTHR18919:SF109 26 318 1.1E-125 T 22-04-2016 TOLA_RS11140 b92c368f2634cd543c4b3b9612929f07 318 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 183 1.1E-30 T 22-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 TOLA_RS11140 b92c368f2634cd543c4b3b9612929f07 318 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 318 68.827 T 22-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 TOLA_RS03440 6bb300a3259d14938d7754c6a96b332f 231 SUPERFAMILY SSF52540 1 227 1.24E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03440 6bb300a3259d14938d7754c6a96b332f 231 SMART SM00382 24 218 2.5E-14 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS03440 6bb300a3259d14938d7754c6a96b332f 231 TIGRFAM TIGR01277 thiQ: thiamine ABC transporter, ATP-binding protein 8 210 1.6E-76 T 22-04-2016 IPR005968 Thiamine ABC transporter, ATP-binding protein ThiQ GO:0005524|GO:0006810|GO:0016021|GO:0042626 TOLA_RS03440 6bb300a3259d14938d7754c6a96b332f 231 PANTHER PTHR24220 19 229 6.2E-72 T 22-04-2016 TOLA_RS03440 6bb300a3259d14938d7754c6a96b332f 231 Gene3D G3DSA:3.40.50.300 17 229 5.2E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03440 6bb300a3259d14938d7754c6a96b332f 231 Pfam PF00005 ABC transporter 17 157 1.2E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS03440 6bb300a3259d14938d7754c6a96b332f 231 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS02650 a0321fe9aedcd0a529595459ecc95d89 493 PANTHER PTHR11730:SF17 230 493 2.4E-173 T 22-04-2016 TOLA_RS02650 a0321fe9aedcd0a529595459ecc95d89 493 PANTHER PTHR11730:SF17 34 211 2.4E-173 T 22-04-2016 TOLA_RS02650 a0321fe9aedcd0a529595459ecc95d89 493 TIGRFAM TIGR00836 amt: ammonium transporter 63 491 1.2E-127 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 TOLA_RS02650 a0321fe9aedcd0a529595459ecc95d89 493 PANTHER PTHR11730 230 493 2.4E-173 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 TOLA_RS02650 a0321fe9aedcd0a529595459ecc95d89 493 PANTHER PTHR11730 34 211 2.4E-173 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 TOLA_RS02650 a0321fe9aedcd0a529595459ecc95d89 493 SUPERFAMILY SSF111352 59 472 7.19E-121 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 TOLA_RS02650 a0321fe9aedcd0a529595459ecc95d89 493 Gene3D G3DSA:1.10.3430.10 58 472 3.5E-135 T 22-04-2016 IPR029020 Ammonium/urea transporter TOLA_RS02650 a0321fe9aedcd0a529595459ecc95d89 493 Pfam PF00909 Ammonium Transporter Family 65 491 7.8E-115 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 TOLA_RS02650 a0321fe9aedcd0a529595459ecc95d89 493 ProSitePatterns PS01219 Ammonium transporters signature. 239 264 - T 22-04-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 TOLA_RS03985 c687f4c1c82fe6361ea7c12d33c4feab 602 SUPERFAMILY SSF143975 1 416 1.11E-132 T 22-04-2016 TOLA_RS03985 c687f4c1c82fe6361ea7c12d33c4feab 602 Pfam PF00920 Dehydratase family 67 593 1.3E-149 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS03985 c687f4c1c82fe6361ea7c12d33c4feab 602 PANTHER PTHR21000:SF9 1 596 0.0 T 22-04-2016 TOLA_RS03985 c687f4c1c82fe6361ea7c12d33c4feab 602 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 2 596 2.2E-263 T 22-04-2016 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12|UniPathway: UPA00226 TOLA_RS03985 c687f4c1c82fe6361ea7c12d33c4feab 602 PANTHER PTHR21000 1 596 0.0 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS03985 c687f4c1c82fe6361ea7c12d33c4feab 602 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 503 514 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS03985 c687f4c1c82fe6361ea7c12d33c4feab 602 SUPERFAMILY SSF52016 417 597 6.51E-55 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel TOLA_RS03985 c687f4c1c82fe6361ea7c12d33c4feab 602 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 154 164 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS00260 600668e22d025a44796090abeaabe3a6 304 Pfam PF00480 ROK family 3 301 1.1E-87 T 22-04-2016 IPR000600 ROK family TOLA_RS00260 600668e22d025a44796090abeaabe3a6 304 PANTHER PTHR18964:SF123 3 299 9.6E-98 T 22-04-2016 TOLA_RS00260 600668e22d025a44796090abeaabe3a6 304 ProSitePatterns PS01125 ROK family signature. 130 157 - T 22-04-2016 IPR000600 ROK family TOLA_RS00260 600668e22d025a44796090abeaabe3a6 304 Gene3D G3DSA:3.30.420.40 133 280 1.6E-49 T 22-04-2016 TOLA_RS00260 600668e22d025a44796090abeaabe3a6 304 Gene3D G3DSA:3.30.420.40 2 132 2.2E-38 T 22-04-2016 TOLA_RS00260 600668e22d025a44796090abeaabe3a6 304 SUPERFAMILY SSF53067 3 300 1.24E-62 T 22-04-2016 TOLA_RS00260 600668e22d025a44796090abeaabe3a6 304 PANTHER PTHR18964 3 299 9.6E-98 T 22-04-2016 TOLA_RS10035 bca5ed9863067daef88b644d3d07ce2b 509 Gene3D G3DSA:3.40.50.300 261 499 9.2E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10035 bca5ed9863067daef88b644d3d07ce2b 509 Gene3D G3DSA:3.40.50.300 2 240 2.0E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10035 bca5ed9863067daef88b644d3d07ce2b 509 SUPERFAMILY SSF52540 271 504 2.0E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10035 bca5ed9863067daef88b644d3d07ce2b 509 Pfam PF00005 ABC transporter 21 174 1.9E-28 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS10035 bca5ed9863067daef88b644d3d07ce2b 509 Pfam PF00005 ABC transporter 278 436 7.8E-21 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS10035 bca5ed9863067daef88b644d3d07ce2b 509 PANTHER PTHR24220:SF416 7 391 1.8E-170 T 22-04-2016 TOLA_RS10035 bca5ed9863067daef88b644d3d07ce2b 509 SUPERFAMILY SSF52540 4 234 5.54E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10035 bca5ed9863067daef88b644d3d07ce2b 509 SMART SM00382 30 222 4.0E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS10035 bca5ed9863067daef88b644d3d07ce2b 509 SMART SM00382 287 486 0.0033 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS10035 bca5ed9863067daef88b644d3d07ce2b 509 PANTHER PTHR24220 7 391 1.8E-170 T 22-04-2016 TOLA_RS10035 bca5ed9863067daef88b644d3d07ce2b 509 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS09480 273759cd4bd781802d85e20f251ebc99 286 SUPERFAMILY SSF46689 237 284 6.27E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09480 273759cd4bd781802d85e20f251ebc99 286 Gene3D G3DSA:1.10.10.60 240 284 3.3E-19 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09480 273759cd4bd781802d85e20f251ebc99 286 PANTHER PTHR11019:SF105 24 285 5.4E-39 T 22-04-2016 TOLA_RS09480 273759cd4bd781802d85e20f251ebc99 286 PANTHER PTHR11019 24 285 5.4E-39 T 22-04-2016 TOLA_RS09480 273759cd4bd781802d85e20f251ebc99 286 Pfam PF12833 Helix-turn-helix domain 207 284 4.9E-24 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS09480 273759cd4bd781802d85e20f251ebc99 286 Gene3D G3DSA:1.10.10.60 181 239 1.6E-16 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09480 273759cd4bd781802d85e20f251ebc99 286 SUPERFAMILY SSF46689 185 234 4.17E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09480 273759cd4bd781802d85e20f251ebc99 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 253 268 5.9E-8 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS09480 273759cd4bd781802d85e20f251ebc99 286 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 268 284 5.9E-8 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS09480 273759cd4bd781802d85e20f251ebc99 286 SMART SM00342 201 284 1.4E-31 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS09480 273759cd4bd781802d85e20f251ebc99 286 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 238 280 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TOLA_RS11555 61aa4fb0c400af91d2340ac2ad94c7ea 235 Pfam PF11726 Protein of unknown function (DUF3296) 41 228 8.1E-57 T 22-04-2016 IPR021723 Inovirus Gp2 TOLA_RS01910 0f0c23db5b87d463cc7f3c089aa5e372 115 TIGRFAM TIGR01707 gspI: type II secretion system protein I 1 97 3.8E-27 T 22-04-2016 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 TOLA_RS01910 0f0c23db5b87d463cc7f3c089aa5e372 115 PANTHER PTHR38779 1 115 4.3E-35 T 22-04-2016 TOLA_RS01910 0f0c23db5b87d463cc7f3c089aa5e372 115 PANTHER PTHR38779:SF2 1 115 4.3E-35 T 22-04-2016 TOLA_RS01910 0f0c23db5b87d463cc7f3c089aa5e372 115 Pfam PF13633 Prokaryotic N-terminal methylation site 1 23 7.3E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS01910 0f0c23db5b87d463cc7f3c089aa5e372 115 Pfam PF02501 Type II secretion system (T2SS), protein I 34 112 3.5E-30 T 22-04-2016 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 TOLA_RS01910 0f0c23db5b87d463cc7f3c089aa5e372 115 SUPERFAMILY SSF54523 32 113 5.49E-29 T 22-04-2016 TOLA_RS01910 0f0c23db5b87d463cc7f3c089aa5e372 115 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 1 17 0.0012 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS01910 0f0c23db5b87d463cc7f3c089aa5e372 115 Gene3D G3DSA:3.30.1300.30 27 113 1.5E-32 T 22-04-2016 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 SMART SM00388 475 543 7.4E-19 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 SMART SM00387 589 700 1.2E-33 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 Pfam PF00072 Response regulator receiver domain 743 828 8.2E-6 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 SUPERFAMILY SSF52172 719 842 3.84E-14 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 590 697 3.6E-25 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 PANTHER PTHR24423 14 24 5.7E-80 T 22-04-2016 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 PANTHER PTHR24423 454 841 5.7E-80 T 22-04-2016 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 PANTHER PTHR24423 214 248 5.7E-80 T 22-04-2016 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 Pfam PF02743 Cache domain 168 359 1.7E-17 T 22-04-2016 IPR033479 Double Cache domain 1 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 660 678 1.1E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 644 654 1.1E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 626 640 1.1E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 PRINTS PR00344 Bacterial sensor protein C-terminal signature 684 697 1.1E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 SUPERFAMILY SSF55874 532 696 1.44E-41 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 SUPERFAMILY SSF47384 460 543 3.14E-19 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 Gene3D G3DSA:3.30.565.10 547 696 1.4E-40 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 Gene3D G3DSA:3.40.50.2300 717 841 6.9E-16 T 22-04-2016 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 Gene3D G3DSA:1.10.287.130 469 538 6.5E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 Pfam PF00512 His Kinase A (phospho-acceptor) domain 476 542 8.0E-15 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 Gene3D G3DSA:3.30.450.20 213 294 5.1E-22 T 22-04-2016 TOLA_RS06515 05f709cf6f3fb81d4cf910f746f9d2a5 845 Gene3D G3DSA:3.30.450.20 326 373 5.1E-22 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 SMART SM00450 473 568 4.8E-16 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 SUPERFAMILY SSF51905 2 198 6.94E-43 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 SUPERFAMILY SSF55424 345 467 3.44E-33 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PANTHER PTHR22912:SF140 2 223 4.5E-179 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PANTHER PTHR22912:SF140 242 462 4.5E-179 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 1.9E-23 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.9E-23 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 1.9E-23 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.9E-23 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.9E-23 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 Pfam PF00581 Rhodanese-like domain 484 564 4.9E-9 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 Gene3D G3DSA:3.50.50.60 2 112 6.5E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 350 451 4.1E-13 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 Gene3D G3DSA:3.40.250.10 485 566 2.7E-20 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 SUPERFAMILY SSF52821 462 564 1.23E-21 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 Gene3D G3DSA:3.30.390.30 357 467 4.7E-41 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 327 1.2E-54 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 SUPERFAMILY SSF51905 153 340 2.71E-29 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 Gene3D G3DSA:3.50.50.60 113 337 1.1E-54 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 2.5E-16 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 2.5E-16 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.5E-16 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 2.5E-16 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PANTHER PTHR22912 2 223 4.5E-179 T 22-04-2016 TOLA_RS05655 9df40bf581acf99f891a08ab01124007 569 PANTHER PTHR22912 242 462 4.5E-179 T 22-04-2016 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 ProSitePatterns PS00756 Protein secY signature 2. 171 188 - T 22-04-2016 IPR030659 SecY conserved site TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 Pfam PF00344 SecY translocase 76 417 6.5E-114 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 Hamap MF_01465 Protein translocase subunit SecY [secY]. 10 433 28.521 T 22-04-2016 IPR026593 Protein translocase subunit SecY TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 20 429 2.6E-133 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 SUPERFAMILY SSF103491 16 424 5.62E-128 T 22-04-2016 IPR023201 SecY subunit domain TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 270 289 8.3E-94 T 22-04-2016 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 75 95 8.3E-94 T 22-04-2016 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 315 337 8.3E-94 T 22-04-2016 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 178 201 8.3E-94 T 22-04-2016 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 402 420 8.3E-94 T 22-04-2016 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 370 388 8.3E-94 T 22-04-2016 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 116 139 8.3E-94 T 22-04-2016 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 23 41 8.3E-94 T 22-04-2016 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 PRINTS PR00303 Preprotein translocase SecY subunit signature 152 177 8.3E-94 T 22-04-2016 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 PANTHER PTHR10906 17 443 5.0E-217 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 PANTHER PTHR10906:SF2 17 443 5.0E-217 T 22-04-2016 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 PIRSF PIRSF004557 12 440 1.8E-118 T 22-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 ProSitePatterns PS00755 Protein secY signature 1. 76 95 - T 22-04-2016 IPR030659 SecY conserved site TOLA_RS00620 3ed020b8ecdf319c81ff63d0cc6139da 443 Gene3D G3DSA:1.10.3370.10 16 437 3.5E-159 T 22-04-2016 IPR023201 SecY subunit domain TOLA_RS07150 c60a5b9671851f0bd23c139cf938d464 213 Pfam PF13460 NAD(P)H-binding 7 198 3.0E-32 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS07150 c60a5b9671851f0bd23c139cf938d464 213 SUPERFAMILY SSF51735 1 211 1.95E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS07150 c60a5b9671851f0bd23c139cf938d464 213 PANTHER PTHR15020 1 213 2.6E-67 T 22-04-2016 TOLA_RS07150 c60a5b9671851f0bd23c139cf938d464 213 PANTHER PTHR15020:SF29 1 213 2.6E-67 T 22-04-2016 TOLA_RS07150 c60a5b9671851f0bd23c139cf938d464 213 Gene3D G3DSA:3.40.50.720 1 213 5.1E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09905 e3b3948de40be9e122ca21097ca06279 655 Gene3D G3DSA:1.50.10.10 70 305 2.9E-24 T 22-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 TOLA_RS09905 e3b3948de40be9e122ca21097ca06279 655 PANTHER PTHR31151:SF1 10 241 2.3E-253 T 22-04-2016 TOLA_RS09905 e3b3948de40be9e122ca21097ca06279 655 PANTHER PTHR31151:SF1 267 652 2.3E-253 T 22-04-2016 TOLA_RS09905 e3b3948de40be9e122ca21097ca06279 655 PANTHER PTHR31151 10 241 2.3E-253 T 22-04-2016 TOLA_RS09905 e3b3948de40be9e122ca21097ca06279 655 PANTHER PTHR31151 267 652 2.3E-253 T 22-04-2016 TOLA_RS09905 e3b3948de40be9e122ca21097ca06279 655 SUPERFAMILY SSF48208 16 427 3.16E-41 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 TOLA_RS09905 e3b3948de40be9e122ca21097ca06279 655 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 13 564 4.8E-172 T 22-04-2016 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 TOLA_RS09345 f625d5ed4d4fd324e53c71be949ee1a1 221 PANTHER PTHR36438 1 217 2.0E-81 T 22-04-2016 TOLA_RS09345 f625d5ed4d4fd324e53c71be949ee1a1 221 Gene3D G3DSA:1.20.120.520 66 217 3.7E-25 T 22-04-2016 TOLA_RS09345 f625d5ed4d4fd324e53c71be949ee1a1 221 Pfam PF04405 Domain of Unknown function (DUF542) 5 59 5.5E-22 T 22-04-2016 IPR019903 Repair of iron centres family TOLA_RS09345 f625d5ed4d4fd324e53c71be949ee1a1 221 Pfam PF01814 Hemerythrin HHE cation binding domain 80 215 1.5E-24 T 22-04-2016 IPR012312 Haemerythrin-like TOLA_RS09345 f625d5ed4d4fd324e53c71be949ee1a1 221 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 8 216 1.2E-77 T 22-04-2016 IPR019903 Repair of iron centres family TOLA_RS09345 f625d5ed4d4fd324e53c71be949ee1a1 221 PANTHER PTHR36438:SF1 1 217 2.0E-81 T 22-04-2016 TOLA_RS00820 359dbba3e517bced0c0c11b41ce296c2 186 Pfam PF01300 Telomere recombination 10 186 2.5E-45 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 TOLA_RS00820 359dbba3e517bced0c0c11b41ce296c2 186 PANTHER PTHR17490:SF8 1 181 3.1E-100 T 22-04-2016 TOLA_RS00820 359dbba3e517bced0c0c11b41ce296c2 186 SUPERFAMILY SSF55821 2 183 1.5E-56 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TOLA_RS00820 359dbba3e517bced0c0c11b41ce296c2 186 PANTHER PTHR17490 1 181 3.1E-100 T 22-04-2016 TOLA_RS00820 359dbba3e517bced0c0c11b41ce296c2 186 Gene3D G3DSA:3.90.870.10 3 186 2.0E-57 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TOLA_RS00820 359dbba3e517bced0c0c11b41ce296c2 186 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 2 184 39.95 T 22-04-2016 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 TOLA_RS00820 359dbba3e517bced0c0c11b41ce296c2 186 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 3 184 2.0E-40 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 TOLA_RS11085 56b36421c52a188391c0daa17a7d802e 152 SUPERFAMILY SSF53254 1 118 1.15E-21 T 22-04-2016 IPR029033 Histidine phosphatase superfamily TOLA_RS11085 56b36421c52a188391c0daa17a7d802e 152 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 146 8.9E-38 T 22-04-2016 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0008969 KEGG: 00051+3.1.3.-|KEGG: 00332+3.1.3.-|KEGG: 00565+3.1.3.-|KEGG: 00600+3.1.3.-|KEGG: 00730+3.1.3.-|KEGG: 00740+3.1.3.-|KEGG: 00760+3.1.3.- TOLA_RS11085 56b36421c52a188391c0daa17a7d802e 152 Gene3D G3DSA:3.40.50.1240 1 149 3.1E-39 T 22-04-2016 IPR029033 Histidine phosphatase superfamily TOLA_RS11085 56b36421c52a188391c0daa17a7d802e 152 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 75 2.2E-10 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 TOLA_RS11085 56b36421c52a188391c0daa17a7d802e 152 PANTHER PTHR23029:SF1 1 75 3.0E-16 T 22-04-2016 TOLA_RS11085 56b36421c52a188391c0daa17a7d802e 152 PANTHER PTHR23029 1 75 3.0E-16 T 22-04-2016 TOLA_RS11085 56b36421c52a188391c0daa17a7d802e 152 SMART SM00855 2 112 6.6E-9 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 TOLA_RS00210 c005fefa9a6be5415632130fd2dab22c 369 PANTHER PTHR24220 5 343 8.9E-180 T 22-04-2016 TOLA_RS00210 c005fefa9a6be5415632130fd2dab22c 369 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS00210 c005fefa9a6be5415632130fd2dab22c 369 PANTHER PTHR24220:SF572 5 343 8.9E-180 T 22-04-2016 TOLA_RS00210 c005fefa9a6be5415632130fd2dab22c 369 Pfam PF00005 ABC transporter 20 161 3.5E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS00210 c005fefa9a6be5415632130fd2dab22c 369 SUPERFAMILY SSF52540 4 244 5.86E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00210 c005fefa9a6be5415632130fd2dab22c 369 SMART SM00382 28 211 9.3E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS00210 c005fefa9a6be5415632130fd2dab22c 369 SUPERFAMILY SSF50331 236 363 7.02E-31 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS00210 c005fefa9a6be5415632130fd2dab22c 369 Gene3D G3DSA:3.40.50.300 4 235 1.3E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00210 c005fefa9a6be5415632130fd2dab22c 369 Gene3D G3DSA:2.40.50.140 288 345 8.1E-24 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS00210 c005fefa9a6be5415632130fd2dab22c 369 Pfam PF08402 TOBE domain 281 353 1.2E-11 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 TOLA_RS00210 c005fefa9a6be5415632130fd2dab22c 369 Gene3D G3DSA:2.40.50.100 347 361 7.7E-27 T 22-04-2016 TOLA_RS00210 c005fefa9a6be5415632130fd2dab22c 369 Gene3D G3DSA:2.40.50.100 239 287 7.7E-27 T 22-04-2016 TOLA_RS09835 06f8c86a608f6f56be6bfddef5e60369 316 Gene3D G3DSA:1.10.10.60 199 256 4.2E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09835 06f8c86a608f6f56be6bfddef5e60369 316 Pfam PF12833 Helix-turn-helix domain 225 299 1.1E-17 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS09835 06f8c86a608f6f56be6bfddef5e60369 316 SMART SM00342 219 302 1.3E-20 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS09835 06f8c86a608f6f56be6bfddef5e60369 316 Gene3D G3DSA:1.10.10.60 257 299 3.9E-9 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09835 06f8c86a608f6f56be6bfddef5e60369 316 Pfam PF06719 AraC-type transcriptional regulator N-terminus 40 188 2.3E-40 T 22-04-2016 IPR009594 Transcription regulator HTH, AraC, N-terminal TOLA_RS09835 06f8c86a608f6f56be6bfddef5e60369 316 PANTHER PTHR11019 40 310 1.9E-78 T 22-04-2016 TOLA_RS09835 06f8c86a608f6f56be6bfddef5e60369 316 SUPERFAMILY SSF46689 255 300 5.82E-8 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09835 06f8c86a608f6f56be6bfddef5e60369 316 SUPERFAMILY SSF46689 202 252 2.24E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09835 06f8c86a608f6f56be6bfddef5e60369 316 PANTHER PTHR11019:SF81 40 310 1.9E-78 T 22-04-2016 TOLA_RS05335 5579c50445224d7a66ec029226d3cced 526 PANTHER PTHR34987 70 523 2.7E-38 T 22-04-2016 TOLA_RS05335 5579c50445224d7a66ec029226d3cced 526 PANTHER PTHR34987:SF1 70 523 2.7E-38 T 22-04-2016 TOLA_RS05335 5579c50445224d7a66ec029226d3cced 526 SUPERFAMILY SSF48208 191 520 1.06E-38 T 22-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 TOLA_RS05335 5579c50445224d7a66ec029226d3cced 526 Pfam PF05592 Bacterial alpha-L-rhamnosidase 145 522 2.0E-27 T 22-04-2016 IPR008902 Bacterial alpha-L-rhamnosidase TOLA_RS14405 d9ee9cfbc8e44a9a7b55e0c2d4f9dd3e 618 ProSitePatterns PS01276 Peptidase family U32 signature. 160 178 - T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS14405 d9ee9cfbc8e44a9a7b55e0c2d4f9dd3e 618 Pfam PF01136 Peptidase family U32 78 303 3.5E-71 T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS14405 d9ee9cfbc8e44a9a7b55e0c2d4f9dd3e 618 PANTHER PTHR30217:SF10 1 613 1.1E-213 T 22-04-2016 TOLA_RS14405 d9ee9cfbc8e44a9a7b55e0c2d4f9dd3e 618 Pfam PF12392 Collagenase 382 496 2.9E-27 T 22-04-2016 IPR020988 Peptidase U32, collagenase KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS14405 d9ee9cfbc8e44a9a7b55e0c2d4f9dd3e 618 PANTHER PTHR30217 1 613 1.1E-213 T 22-04-2016 TOLA_RS02200 5f9ad5d86e6bb1b8cca77fbcb83687ef 132 PIRSF PIRSF016821 7 132 1.6E-41 T 22-04-2016 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 TOLA_RS02200 5f9ad5d86e6bb1b8cca77fbcb83687ef 132 PANTHER PTHR11079 6 102 2.5E-27 T 22-04-2016 TOLA_RS02200 5f9ad5d86e6bb1b8cca77fbcb83687ef 132 PANTHER PTHR11079:SF70 6 102 2.5E-27 T 22-04-2016 TOLA_RS02200 5f9ad5d86e6bb1b8cca77fbcb83687ef 132 Gene3D G3DSA:3.10.290.10 9 104 1.1E-35 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS02200 5f9ad5d86e6bb1b8cca77fbcb83687ef 132 SMART SM00363 10 75 9.3E-10 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS02200 5f9ad5d86e6bb1b8cca77fbcb83687ef 132 SUPERFAMILY SSF55174 10 105 5.36E-29 T 22-04-2016 TOLA_RS02200 5f9ad5d86e6bb1b8cca77fbcb83687ef 132 Pfam PF01479 S4 domain 11 55 1.4E-12 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS16210 f4c7e520263e868f3ad30e9e1674a8e5 335 PANTHER PTHR30004:SF6 3 335 2.4E-125 T 22-04-2016 TOLA_RS16210 f4c7e520263e868f3ad30e9e1674a8e5 335 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 36 322 3.8E-89 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 TOLA_RS16210 f4c7e520263e868f3ad30e9e1674a8e5 335 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 5 330 29.036 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 TOLA_RS16210 f4c7e520263e868f3ad30e9e1674a8e5 335 SUPERFAMILY SSF53659 7 330 1.86E-91 T 22-04-2016 TOLA_RS16210 f4c7e520263e868f3ad30e9e1674a8e5 335 Gene3D G3DSA:3.40.718.10 4 328 1.0E-108 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 TOLA_RS16210 f4c7e520263e868f3ad30e9e1674a8e5 335 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 9 327 3.2E-88 T 22-04-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 TOLA_RS16210 f4c7e520263e868f3ad30e9e1674a8e5 335 PANTHER PTHR30004 3 335 2.4E-125 T 22-04-2016 TOLA_RS09445 25d3c3168e5ec717bd6d78f1c560f7ff 170 Pfam PF13463 Winged helix DNA-binding domain 52 117 2.0E-18 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS09445 25d3c3168e5ec717bd6d78f1c560f7ff 170 Gene3D G3DSA:1.10.10.10 30 160 2.8E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09445 25d3c3168e5ec717bd6d78f1c560f7ff 170 SUPERFAMILY SSF46785 25 161 1.42E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09445 25d3c3168e5ec717bd6d78f1c560f7ff 170 PIRSF PIRSF036158 1 170 9.9E-62 T 22-04-2016 IPR014601 Transcriptional regulator with MarR-type HTH domain TOLA_RS15530 c17aec3df76b693dd637aa51548115f3 470 Pfam PF02614 Glucuronate isomerase 1 465 4.0E-216 T 22-04-2016 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248|UniPathway: UPA00246 TOLA_RS15530 c17aec3df76b693dd637aa51548115f3 470 SUPERFAMILY SSF51556 3 466 1.63E-176 T 22-04-2016 IPR032466 Metal-dependent hydrolase TOLA_RS15530 c17aec3df76b693dd637aa51548115f3 470 Gene3D G3DSA:1.10.2020.10 46 137 1.9E-39 T 22-04-2016 IPR023177 Uronate isomerase, domain 2 GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248|UniPathway: UPA00246 TOLA_RS15530 c17aec3df76b693dd637aa51548115f3 470 PANTHER PTHR30068:SF4 2 469 1.6E-271 T 22-04-2016 TOLA_RS15530 c17aec3df76b693dd637aa51548115f3 470 Gene3D G3DSA:3.20.20.140 4 44 1.4E-159 T 22-04-2016 TOLA_RS15530 c17aec3df76b693dd637aa51548115f3 470 Gene3D G3DSA:3.20.20.140 139 466 1.4E-159 T 22-04-2016 TOLA_RS15530 c17aec3df76b693dd637aa51548115f3 470 PANTHER PTHR30068 2 469 1.6E-271 T 22-04-2016 TOLA_RS15530 c17aec3df76b693dd637aa51548115f3 470 Hamap MF_00675 Uronate isomerase [uxaC]. 2 467 48.276 T 22-04-2016 IPR003766 Uronate isomerase GO:0006064|GO:0008880 KEGG: 00040+5.3.1.12|MetaCyc: PWY-7247|MetaCyc: PWY-7248|UniPathway: UPA00246 TOLA_RS01545 dbf4e2e88e1c8b20c2ece4f0c7e4b4fe 659 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS01545 dbf4e2e88e1c8b20c2ece4f0c7e4b4fe 659 Pfam PF12704 MacB-like periplasmic core domain 284 502 3.3E-36 T 22-04-2016 IPR025857 MacB-like periplasmic core domain TOLA_RS01545 dbf4e2e88e1c8b20c2ece4f0c7e4b4fe 659 Pfam PF02687 FtsX-like permease family 539 652 1.4E-21 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 TOLA_RS01545 dbf4e2e88e1c8b20c2ece4f0c7e4b4fe 659 PANTHER PTHR24220:SF86 11 232 7.2E-102 T 22-04-2016 TOLA_RS01545 dbf4e2e88e1c8b20c2ece4f0c7e4b4fe 659 Pfam PF00005 ABC transporter 29 177 3.9E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS01545 dbf4e2e88e1c8b20c2ece4f0c7e4b4fe 659 SUPERFAMILY SSF52540 9 231 8.22E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01545 dbf4e2e88e1c8b20c2ece4f0c7e4b4fe 659 SMART SM00382 38 225 4.5E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS01545 dbf4e2e88e1c8b20c2ece4f0c7e4b4fe 659 Gene3D G3DSA:3.40.50.300 8 229 4.9E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01545 dbf4e2e88e1c8b20c2ece4f0c7e4b4fe 659 PANTHER PTHR24220 11 232 7.2E-102 T 22-04-2016 TOLA_RS07210 072cc5a2d1059b9167d9e4484bc07567 517 SUPERFAMILY SSF51126 159 417 1.14E-23 T 22-04-2016 IPR011050 Pectin lyase fold/virulence factor TOLA_RS07210 072cc5a2d1059b9167d9e4484bc07567 517 SMART SM00710 248 269 4800.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07210 072cc5a2d1059b9167d9e4484bc07567 517 SMART SM00710 319 341 1400.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07210 072cc5a2d1059b9167d9e4484bc07567 517 SMART SM00710 270 292 580.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07210 072cc5a2d1059b9167d9e4484bc07567 517 SMART SM00710 366 388 22.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07210 072cc5a2d1059b9167d9e4484bc07567 517 SMART SM00710 343 365 170.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07210 072cc5a2d1059b9167d9e4484bc07567 517 SMART SM00710 389 411 6400.0 T 22-04-2016 IPR006626 Parallel beta-helix repeat TOLA_RS07210 072cc5a2d1059b9167d9e4484bc07567 517 Gene3D G3DSA:2.160.20.10 312 484 8.1E-10 T 22-04-2016 IPR012334 Pectin lyase fold TOLA_RS07210 072cc5a2d1059b9167d9e4484bc07567 517 Pfam PF05048 Periplasmic copper-binding protein (NosD) 243 402 8.8E-13 T 22-04-2016 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain TOLA_RS07210 072cc5a2d1059b9167d9e4484bc07567 517 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 336 380 1.1E-4 T 22-04-2016 IPR022441 Parallel beta-helix repeat-2 TOLA_RS10855 d25fcd530e336e995ee83b02cac9fdd6 266 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 247 40.591 T 22-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 TOLA_RS10855 d25fcd530e336e995ee83b02cac9fdd6 266 PANTHER PTHR11280 1 260 1.9E-169 T 22-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 TOLA_RS10855 d25fcd530e336e995ee83b02cac9fdd6 266 Gene3D G3DSA:3.40.50.1360 1 260 2.1E-107 T 22-04-2016 TOLA_RS10855 d25fcd530e336e995ee83b02cac9fdd6 266 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 15 221 1.1E-16 T 22-04-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 TOLA_RS10855 d25fcd530e336e995ee83b02cac9fdd6 266 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 125 143 - T 22-04-2016 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 TOLA_RS10855 d25fcd530e336e995ee83b02cac9fdd6 266 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 259 1.2E-127 T 22-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 TOLA_RS10855 d25fcd530e336e995ee83b02cac9fdd6 266 SUPERFAMILY SSF100950 1 262 1.99E-102 T 22-04-2016 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 SUPERFAMILY SSF53732 2 465 1.24E-166 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PANTHER PTHR11670 1 307 5.2E-275 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PANTHER PTHR11670 327 465 5.2E-275 T 22-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PRINTS PR00415 Aconitase family signature 133 148 3.4E-48 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PRINTS PR00415 Aconitase family signature 209 222 3.4E-48 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PRINTS PR00415 Aconitase family signature 195 208 3.4E-48 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PRINTS PR00415 Aconitase family signature 286 300 3.4E-48 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PRINTS PR00415 Aconitase family signature 82 95 3.4E-48 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PRINTS PR00415 Aconitase family signature 399 412 3.4E-48 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PRINTS PR00415 Aconitase family signature 119 132 3.4E-48 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PRINTS PR00415 Aconitase family signature 108 116 3.4E-48 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PRINTS PR00415 Aconitase family signature 343 354 3.4E-48 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 Gene3D G3DSA:3.30.499.10 330 465 4.4E-64 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 465 3.8E-259 T 22-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PANTHER PTHR11670:SF38 1 307 5.2E-275 T 22-04-2016 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 PANTHER PTHR11670:SF38 327 465 5.2E-275 T 22-04-2016 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 465 59.98 T 22-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 Gene3D G3DSA:3.40.1060.10 166 280 1.2E-40 T 22-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 2.9E-156 T 22-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 Gene3D G3DSA:3.30.499.10 2 158 2.4E-23 T 22-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS03500 0dbb5077ad5c7eca0412ec6f3bb73177 465 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 22-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 TOLA_RS00825 86d28e35752c6778b29408dd320b849b 273 SUPERFAMILY SSF51735 102 268 2.01E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00825 86d28e35752c6778b29408dd320b849b 273 PANTHER PTHR21089 1 270 5.1E-143 T 22-04-2016 TOLA_RS00825 86d28e35752c6778b29408dd320b849b 273 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 88 6.0E-25 T 22-04-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS00825 86d28e35752c6778b29408dd320b849b 273 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 269 32.438 T 22-04-2016 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS00825 86d28e35752c6778b29408dd320b849b 273 PANTHER PTHR21089:SF2 1 270 5.1E-143 T 22-04-2016 TOLA_RS00825 86d28e35752c6778b29408dd320b849b 273 SUPERFAMILY SSF53223 1 101 7.48E-32 T 22-04-2016 TOLA_RS00825 86d28e35752c6778b29408dd320b849b 273 Gene3D G3DSA:3.40.192.10 1 107 1.1E-37 T 22-04-2016 TOLA_RS00825 86d28e35752c6778b29408dd320b849b 273 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 113 191 1.8E-13 T 22-04-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TOLA_RS00825 86d28e35752c6778b29408dd320b849b 273 Gene3D G3DSA:3.40.50.720 108 244 1.3E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00825 86d28e35752c6778b29408dd320b849b 273 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 270 1.2E-84 T 22-04-2016 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 Gene3D G3DSA:2.60.34.10 390 531 7.4E-72 T 22-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 Pfam PF00012 Hsp70 protein 4 602 3.9E-260 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 Gene3D G3DSA:1.20.1270.10 532 601 8.5E-25 T 22-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 Gene3D G3DSA:3.30.30.30 53 106 3.4E-27 T 22-04-2016 TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 PRINTS PR00301 70kDa heat shock protein signature 138 158 3.4E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 PRINTS PR00301 70kDa heat shock protein signature 334 350 3.4E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 PRINTS PR00301 70kDa heat shock protein signature 469 485 3.4E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 PRINTS PR00301 70kDa heat shock protein signature 388 407 3.4E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 PRINTS PR00301 70kDa heat shock protein signature 31 43 3.4E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 PRINTS PR00301 70kDa heat shock protein signature 198 208 3.4E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 PRINTS PR00301 70kDa heat shock protein signature 365 385 3.4E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 PRINTS PR00301 70kDa heat shock protein signature 54 62 3.4E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 PRINTS PR00301 70kDa heat shock protein signature 3 16 3.4E-78 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 603 9.8E-290 T 22-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 Gene3D G3DSA:3.30.420.40 119 192 2.6E-62 T 22-04-2016 TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 Gene3D G3DSA:3.30.420.40 4 52 2.6E-62 T 22-04-2016 TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 SUPERFAMILY SSF53067 4 182 2.73E-64 T 22-04-2016 TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 PANTHER PTHR19375 2 643 0.0 T 22-04-2016 TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 PANTHER PTHR19375:SF173 2 643 0.0 T 22-04-2016 TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 SUPERFAMILY SSF100920 384 540 1.19E-61 T 22-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 SUPERFAMILY SSF53067 187 382 6.17E-68 T 22-04-2016 TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 Gene3D G3DSA:3.90.640.10 230 314 2.4E-31 T 22-04-2016 TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 639 36.525 T 22-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 Gene3D G3DSA:3.30.420.40 193 229 3.1E-33 T 22-04-2016 TOLA_RS11465 75b3f7c986af5e6639cc22c2bdac4b92 644 Gene3D G3DSA:3.30.420.40 319 361 3.1E-33 T 22-04-2016 TOLA_RS04360 680a5c4b631fdde2f2978120de84be36 223 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 219 30.67 T 22-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 TOLA_RS04360 680a5c4b631fdde2f2978120de84be36 223 Gene3D G3DSA:3.30.160.20 152 222 7.9E-28 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain TOLA_RS04360 680a5c4b631fdde2f2978120de84be36 223 SMART SM00535 20 148 5.3E-58 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 TOLA_RS04360 680a5c4b631fdde2f2978120de84be36 223 SUPERFAMILY SSF54768 108 222 3.3E-28 T 22-04-2016 TOLA_RS04360 680a5c4b631fdde2f2978120de84be36 223 SMART SM00358 155 223 1.2E-21 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain TOLA_RS04360 680a5c4b631fdde2f2978120de84be36 223 SUPERFAMILY SSF69065 4 158 2.27E-52 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 TOLA_RS04360 680a5c4b631fdde2f2978120de84be36 223 Pfam PF00035 Double-stranded RNA binding motif 155 222 1.2E-15 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain TOLA_RS04360 680a5c4b631fdde2f2978120de84be36 223 Pfam PF14622 Ribonuclease-III-like 18 139 5.6E-34 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 TOLA_RS04360 680a5c4b631fdde2f2978120de84be36 223 PANTHER PTHR11207 2 222 2.9E-97 T 22-04-2016 TOLA_RS04360 680a5c4b631fdde2f2978120de84be36 223 Gene3D G3DSA:1.10.1520.10 3 146 2.7E-49 T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 TOLA_RS04360 680a5c4b631fdde2f2978120de84be36 223 ProSitePatterns PS00517 Ribonuclease III family signature. 37 45 - T 22-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 TOLA_RS04360 680a5c4b631fdde2f2978120de84be36 223 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 8 222 1.8E-75 T 22-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 TOLA_RS02355 84465cce1acdeb442bf71f2961cefd07 101 PANTHER PTHR34581 2 101 3.0E-40 T 22-04-2016 TOLA_RS02355 84465cce1acdeb442bf71f2961cefd07 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 3.2E-18 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS02355 84465cce1acdeb442bf71f2961cefd07 101 Gene3D G3DSA:3.40.50.270 1 101 2.6E-38 T 22-04-2016 TOLA_RS02355 84465cce1acdeb442bf71f2961cefd07 101 SUPERFAMILY SSF52794 1 101 4.45E-35 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS02355 84465cce1acdeb442bf71f2961cefd07 101 PANTHER PTHR34581:SF2 2 101 3.0E-40 T 22-04-2016 TOLA_RS10955 8a008e0d09e46b44f306637cdfb30619 332 PANTHER PTHR32196 1 329 5.9E-189 T 22-04-2016 TOLA_RS10955 8a008e0d09e46b44f306637cdfb30619 332 PANTHER PTHR32196:SF37 1 329 5.9E-189 T 22-04-2016 TOLA_RS10955 8a008e0d09e46b44f306637cdfb30619 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 319 3.3E-42 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS12105 18891ee10de7cfa5572e105ef11c4018 432 Gene3D G3DSA:3.40.440.10 196 266 3.5E-72 T 22-04-2016 TOLA_RS12105 18891ee10de7cfa5572e105ef11c4018 432 Gene3D G3DSA:3.40.440.10 3 94 3.5E-72 T 22-04-2016 TOLA_RS12105 18891ee10de7cfa5572e105ef11c4018 432 PANTHER PTHR11846 1 429 1.6E-257 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 TOLA_RS12105 18891ee10de7cfa5572e105ef11c4018 432 Gene3D G3DSA:1.10.300.10 103 195 1.1E-37 T 22-04-2016 TOLA_RS12105 18891ee10de7cfa5572e105ef11c4018 432 SUPERFAMILY SSF52540 4 430 1.59E-181 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12105 18891ee10de7cfa5572e105ef11c4018 432 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 22-04-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 TOLA_RS12105 18891ee10de7cfa5572e105ef11c4018 432 Gene3D G3DSA:3.90.170.10 267 426 5.9E-66 T 22-04-2016 TOLA_RS12105 18891ee10de7cfa5572e105ef11c4018 432 Pfam PF00709 Adenylosuccinate synthetase 5 423 5.1E-177 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 TOLA_RS12105 18891ee10de7cfa5572e105ef11c4018 432 SMART SM00788 4 425 2.3E-297 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 TOLA_RS12105 18891ee10de7cfa5572e105ef11c4018 432 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 430 1.3E-195 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 TOLA_RS12105 18891ee10de7cfa5572e105ef11c4018 432 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 22-04-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|UniPathway: UPA00075 TOLA_RS12105 18891ee10de7cfa5572e105ef11c4018 432 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 432 215.391 T 22-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 TOLA_RS14745 2b03cef5bfe573cd25407859d24b8b3a 151 Pfam PF01381 Helix-turn-helix 60 96 1.4E-8 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS14745 2b03cef5bfe573cd25407859d24b8b3a 151 SUPERFAMILY SSF47413 57 99 3.67E-10 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS14745 2b03cef5bfe573cd25407859d24b8b3a 151 Gene3D G3DSA:1.10.260.40 57 98 4.6E-12 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS14745 2b03cef5bfe573cd25407859d24b8b3a 151 SMART SM00530 59 113 4.8E-4 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS09780 cfe2046623a8f92a5d26dd475d1efd4c 246 Gene3D G3DSA:3.60.21.10 1 125 8.5E-22 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS09780 cfe2046623a8f92a5d26dd475d1efd4c 246 Gene3D G3DSA:3.60.21.10 173 204 8.5E-22 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS09780 cfe2046623a8f92a5d26dd475d1efd4c 246 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 242 117.741 T 22-04-2016 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54|UniPathway: UPA00359 TOLA_RS09780 cfe2046623a8f92a5d26dd475d1efd4c 246 SUPERFAMILY SSF56300 2 230 2.66E-25 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS09780 cfe2046623a8f92a5d26dd475d1efd4c 246 PANTHER PTHR34990 1 243 1.6E-104 T 22-04-2016 TOLA_RS09780 cfe2046623a8f92a5d26dd475d1efd4c 246 Pfam PF00149 Calcineurin-like phosphoesterase 4 199 3.6E-8 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 TOLA_RS09780 cfe2046623a8f92a5d26dd475d1efd4c 246 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 4 232 2.6E-95 T 22-04-2016 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54|UniPathway: UPA00359 TOLA_RS09780 cfe2046623a8f92a5d26dd475d1efd4c 246 PANTHER PTHR34990:SF1 1 243 1.6E-104 T 22-04-2016 TOLA_RS00590 1181c72e5dc6c96fadc8804af0479819 130 SUPERFAMILY SSF56047 5 129 8.9E-46 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00590 1181c72e5dc6c96fadc8804af0479819 130 PANTHER PTHR11758 1 130 8.9E-60 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00590 1181c72e5dc6c96fadc8804af0479819 130 Pfam PF00410 Ribosomal protein S8 5 129 7.2E-47 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00590 1181c72e5dc6c96fadc8804af0479819 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00590 1181c72e5dc6c96fadc8804af0479819 130 Gene3D G3DSA:3.30.1490.10 75 129 2.0E-27 T 22-04-2016 TOLA_RS00590 1181c72e5dc6c96fadc8804af0479819 130 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 130 31.574 T 22-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00590 1181c72e5dc6c96fadc8804af0479819 130 Gene3D G3DSA:3.30.1370.30 2 72 2.0E-27 T 22-04-2016 TOLA_RS14715 cc0109d10950f1fb9833fad9eefe7b5e 268 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 6 251 7.2E-46 T 22-04-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 TOLA_RS14715 cc0109d10950f1fb9833fad9eefe7b5e 268 SUPERFAMILY SSF53213 3 258 1.7E-91 T 22-04-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 TOLA_RS14715 cc0109d10950f1fb9833fad9eefe7b5e 268 Gene3D G3DSA:3.40.830.10 1 258 2.8E-95 T 22-04-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 TOLA_RS14715 cc0109d10950f1fb9833fad9eefe7b5e 268 PIRSF PIRSF006157 1 259 2.7E-91 T 22-04-2016 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA type GO:0008270|GO:0016701|GO:0055114 TOLA_RS14715 cc0109d10950f1fb9833fad9eefe7b5e 268 PANTHER PTHR30096 1 261 3.6E-101 T 22-04-2016 TOLA_RS04975 51c38f263309701fc6119302589d5f24 368 PANTHER PTHR30486 1 351 1.0E-148 T 22-04-2016 TOLA_RS04975 51c38f263309701fc6119302589d5f24 368 SUPERFAMILY SSF52540 5 337 1.14E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04975 51c38f263309701fc6119302589d5f24 368 Gene3D G3DSA:3.40.50.300 114 343 3.4E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04975 51c38f263309701fc6119302589d5f24 368 PANTHER PTHR30486:SF3 1 351 1.0E-148 T 22-04-2016 TOLA_RS04975 51c38f263309701fc6119302589d5f24 368 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 344 7.6E-124 T 22-04-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 TOLA_RS04975 51c38f263309701fc6119302589d5f24 368 Pfam PF00437 Type II/IV secretion system protein 119 269 2.8E-38 T 22-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 TOLA_RS11790 a89c7b8388102c1e262ebb6db5f1df97 72 SUPERFAMILY SSF50249 1 70 4.46E-28 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS11790 a89c7b8388102c1e262ebb6db5f1df97 72 Gene3D G3DSA:2.40.50.140 1 71 5.8E-38 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS11790 a89c7b8388102c1e262ebb6db5f1df97 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.956 T 22-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TOLA_RS11790 a89c7b8388102c1e262ebb6db5f1df97 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 4.2E-38 T 22-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TOLA_RS11790 a89c7b8388102c1e262ebb6db5f1df97 72 PANTHER PTHR33370 1 72 6.1E-49 T 22-04-2016 TOLA_RS11790 a89c7b8388102c1e262ebb6db5f1df97 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.0E-26 T 22-04-2016 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 TOLA_RS11790 a89c7b8388102c1e262ebb6db5f1df97 72 SMART SM00316 4 72 1.6E-6 T 22-04-2016 IPR022967 RNA-binding domain, S1 TOLA_RS10000 93085cc5343b8810d88283f69894ed46 307 SUPERFAMILY SSF88713 4 301 6.67E-92 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TOLA_RS10000 93085cc5343b8810d88283f69894ed46 307 Pfam PF01522 Polysaccharide deacetylase 75 164 3.5E-13 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 TOLA_RS10000 93085cc5343b8810d88283f69894ed46 307 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 4 300 1.0E-159 T 22-04-2016 IPR017625 Putative urate catabolism protein TOLA_RS10000 93085cc5343b8810d88283f69894ed46 307 PANTHER PTHR10587:SF72 8 298 2.6E-158 T 22-04-2016 TOLA_RS10000 93085cc5343b8810d88283f69894ed46 307 PANTHER PTHR10587 8 298 2.6E-158 T 22-04-2016 TOLA_RS10000 93085cc5343b8810d88283f69894ed46 307 Gene3D G3DSA:3.20.20.370 4 301 3.0E-104 T 22-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 TOLA_RS01535 0d3053b4d7009b4102df82c010b37010 456 PANTHER PTHR11206:SF48 11 445 1.4E-150 T 22-04-2016 TOLA_RS01535 0d3053b4d7009b4102df82c010b37010 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 18 417 5.1E-62 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 TOLA_RS01535 0d3053b4d7009b4102df82c010b37010 456 PIRSF PIRSF006603 7 452 7.9E-79 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 TOLA_RS01535 0d3053b4d7009b4102df82c010b37010 456 Pfam PF01554 MatE 243 404 2.0E-25 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 TOLA_RS01535 0d3053b4d7009b4102df82c010b37010 456 Pfam PF01554 MatE 18 177 5.7E-28 T 22-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 TOLA_RS01535 0d3053b4d7009b4102df82c010b37010 456 PANTHER PTHR11206 11 445 1.4E-150 T 22-04-2016 TOLA_RS02005 177477b9207b7ca60fa05040625369eb 244 ProSitePatterns PS00162 Alpha-carbonic anhydrases signature. 114 130 - T 22-04-2016 IPR018338 Carbonic anhydrase, alpha-class, conserved site GO:0004089|GO:0006730|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TOLA_RS02005 177477b9207b7ca60fa05040625369eb 244 PANTHER PTHR18952:SF122 19 243 2.9E-75 T 22-04-2016 TOLA_RS02005 177477b9207b7ca60fa05040625369eb 244 SMART SM01057 26 243 1.9E-96 T 22-04-2016 IPR001148 Alpha carbonic anhydrase TOLA_RS02005 177477b9207b7ca60fa05040625369eb 244 Gene3D G3DSA:3.10.200.10 24 242 2.7E-67 T 22-04-2016 IPR001148 Alpha carbonic anhydrase TOLA_RS02005 177477b9207b7ca60fa05040625369eb 244 SUPERFAMILY SSF51069 25 242 3.09E-73 T 22-04-2016 IPR001148 Alpha carbonic anhydrase TOLA_RS02005 177477b9207b7ca60fa05040625369eb 244 Pfam PF00194 Eukaryotic-type carbonic anhydrase 25 242 2.3E-46 T 22-04-2016 IPR001148 Alpha carbonic anhydrase TOLA_RS02005 177477b9207b7ca60fa05040625369eb 244 PANTHER PTHR18952 19 243 2.9E-75 T 22-04-2016 IPR023561 Carbonic anhydrase, alpha-class TOLA_RS07100 6b6f908f40c24a4e30dddf91e3a036fe 468 PANTHER PTHR24031 1 375 1.8E-139 T 22-04-2016 TOLA_RS07100 6b6f908f40c24a4e30dddf91e3a036fe 468 Pfam PF00271 Helicase conserved C-terminal domain 236 341 5.8E-27 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS07100 6b6f908f40c24a4e30dddf91e3a036fe 468 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TOLA_RS07100 6b6f908f40c24a4e30dddf91e3a036fe 468 Pfam PF00270 DEAD/DEAH box helicase 25 196 1.2E-45 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS07100 6b6f908f40c24a4e30dddf91e3a036fe 468 Gene3D G3DSA:3.40.50.300 2 220 3.0E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07100 6b6f908f40c24a4e30dddf91e3a036fe 468 SMART SM00490 260 341 8.6E-32 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS07100 6b6f908f40c24a4e30dddf91e3a036fe 468 SMART SM00487 20 223 1.2E-50 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS07100 6b6f908f40c24a4e30dddf91e3a036fe 468 Gene3D G3DSA:3.40.50.300 221 366 1.1E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07100 6b6f908f40c24a4e30dddf91e3a036fe 468 SUPERFAMILY SSF52540 33 353 3.08E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12545 3f6ab454729b1fb44ccd0185bd6ca90f 922 SMART SM00382 37 258 6.6E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS12545 3f6ab454729b1fb44ccd0185bd6ca90f 922 SMART SM00382 302 487 1.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS12545 3f6ab454729b1fb44ccd0185bd6ca90f 922 PANTHER PTHR24220:SF388 14 397 6.0E-227 T 22-04-2016 TOLA_RS12545 3f6ab454729b1fb44ccd0185bd6ca90f 922 Gene3D G3DSA:3.40.50.300 11 242 5.8E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12545 3f6ab454729b1fb44ccd0185bd6ca90f 922 Gene3D G3DSA:3.40.50.300 274 501 6.8E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12545 3f6ab454729b1fb44ccd0185bd6ca90f 922 Pfam PF12698 ABC-2 family transporter protein 581 914 2.5E-39 T 22-04-2016 TOLA_RS12545 3f6ab454729b1fb44ccd0185bd6ca90f 922 PANTHER PTHR24220 14 397 6.0E-227 T 22-04-2016 TOLA_RS12545 3f6ab454729b1fb44ccd0185bd6ca90f 922 Pfam PF00005 ABC transporter 294 437 2.5E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS12545 3f6ab454729b1fb44ccd0185bd6ca90f 922 Pfam PF00005 ABC transporter 28 175 8.7E-27 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS12545 3f6ab454729b1fb44ccd0185bd6ca90f 922 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS12545 3f6ab454729b1fb44ccd0185bd6ca90f 922 SUPERFAMILY SSF52540 277 498 1.11E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12545 3f6ab454729b1fb44ccd0185bd6ca90f 922 SUPERFAMILY SSF52540 14 239 6.29E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08645 c71039fb231a358c33f7d8b2d7f5072b 182 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 95 158 7.0E-13 T 22-04-2016 TOLA_RS08645 c71039fb231a358c33f7d8b2d7f5072b 182 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 1 63 1.0E-16 T 22-04-2016 TOLA_RS08645 c71039fb231a358c33f7d8b2d7f5072b 182 Pfam PF00936 BMC domain 96 173 2.3E-20 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08645 c71039fb231a358c33f7d8b2d7f5072b 182 Pfam PF00936 BMC domain 4 76 5.2E-21 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08645 c71039fb231a358c33f7d8b2d7f5072b 182 PANTHER PTHR33941:SF3 66 181 1.2E-35 T 22-04-2016 TOLA_RS08645 c71039fb231a358c33f7d8b2d7f5072b 182 PIRSF PIRSF034834 1 182 5.6E-66 T 22-04-2016 IPR011238 Polyhedral organelle shell protein PduT TOLA_RS08645 c71039fb231a358c33f7d8b2d7f5072b 182 SUPERFAMILY SSF143414 3 91 3.01E-22 T 22-04-2016 TOLA_RS08645 c71039fb231a358c33f7d8b2d7f5072b 182 SMART SM00877 3 77 1.8E-22 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08645 c71039fb231a358c33f7d8b2d7f5072b 182 SMART SM00877 95 173 5.8E-24 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08645 c71039fb231a358c33f7d8b2d7f5072b 182 SUPERFAMILY SSF143414 95 181 2.62E-22 T 22-04-2016 TOLA_RS08645 c71039fb231a358c33f7d8b2d7f5072b 182 PANTHER PTHR33941 66 181 1.2E-35 T 22-04-2016 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 SUPERFAMILY SSF82693 40 131 2.09E-23 T 22-04-2016 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 SUPERFAMILY SSF82714 183 264 7.98E-16 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 SUPERFAMILY SSF82714 700 783 2.35E-17 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 Gene3D G3DSA:3.30.2090.10 699 785 1.3E-18 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.3E-77 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 2.3E-77 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.3E-77 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 2.3E-77 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 2.3E-77 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 603 617 2.3E-77 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 2.3E-77 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 2.3E-77 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 2.3E-77 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 SUPERFAMILY SSF82866 785 1004 2.22E-40 T 22-04-2016 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 Gene3D G3DSA:3.30.2090.10 183 264 3.2E-17 T 22-04-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 SUPERFAMILY SSF82693 267 323 4.58E-22 T 22-04-2016 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 SUPERFAMILY SSF82693 137 181 4.58E-22 T 22-04-2016 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 Pfam PF00873 AcrB/AcrD/AcrF family 4 1001 2.1E-261 T 22-04-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 Gene3D G3DSA:3.30.70.1430 40 140 7.3E-28 T 22-04-2016 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 PANTHER PTHR32063 1 1014 0.0 T 22-04-2016 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 PANTHER PTHR32063:SF28 1 1014 0.0 T 22-04-2016 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 SUPERFAMILY SSF82693 553 649 4.18E-16 T 22-04-2016 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 Gene3D G3DSA:3.30.70.1430 556 649 2.1E-12 T 22-04-2016 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 SUPERFAMILY SSF82866 290 489 9.68E-48 T 22-04-2016 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 Gene3D G3DSA:1.10.3850.10 793 1003 1.4E-48 T 22-04-2016 TOLA_RS14920 ed07dd7bd27d1d2c4a144c2775d4708d 1024 Gene3D G3DSA:1.20.1640.10 284 497 2.8E-56 T 22-04-2016 TOLA_RS05640 8878a95fedb8964d62838948aa09fecb 217 PANTHER PTHR21327 1 214 1.3E-146 T 22-04-2016 TOLA_RS05640 8878a95fedb8964d62838948aa09fecb 217 PANTHER PTHR21327:SF15 1 214 1.3E-146 T 22-04-2016 TOLA_RS05640 8878a95fedb8964d62838948aa09fecb 217 Gene3D G3DSA:3.90.870.10 11 214 1.4E-92 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TOLA_RS05640 8878a95fedb8964d62838948aa09fecb 217 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 11 213 41.478 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS05640 8878a95fedb8964d62838948aa09fecb 217 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 17 208 4.1E-82 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS05640 8878a95fedb8964d62838948aa09fecb 217 SUPERFAMILY SSF55821 8 211 3.43E-84 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TOLA_RS05640 8878a95fedb8964d62838948aa09fecb 217 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 13 208 1.3E-81 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS02130 08cc17852df5ed95d2099d30da39ecc8 310 PANTHER PTHR10584 2 307 2.4E-101 T 22-04-2016 TOLA_RS02130 08cc17852df5ed95d2099d30da39ecc8 310 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 4 307 1.6E-92 T 22-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TOLA_RS02130 08cc17852df5ed95d2099d30da39ecc8 310 Pfam PF00294 pfkB family carbohydrate kinase 21 296 7.3E-55 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB TOLA_RS02130 08cc17852df5ed95d2099d30da39ecc8 310 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TOLA_RS02130 08cc17852df5ed95d2099d30da39ecc8 310 PANTHER PTHR10584:SF54 2 307 2.4E-101 T 22-04-2016 TOLA_RS02130 08cc17852df5ed95d2099d30da39ecc8 310 SUPERFAMILY SSF53613 4 297 1.87E-62 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS02130 08cc17852df5ed95d2099d30da39ecc8 310 PIRSF PIRSF000535 1 310 3.0E-92 T 22-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 TOLA_RS02130 08cc17852df5ed95d2099d30da39ecc8 310 Gene3D G3DSA:3.40.1190.20 35 306 2.8E-71 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS02130 08cc17852df5ed95d2099d30da39ecc8 310 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 38 62 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 SUPERFAMILY SSF55874 6 218 1.31E-72 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 SUPERFAMILY SSF56719 395 561 8.11E-86 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 SUPERFAMILY SSF56719 731 796 8.11E-86 T 22-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 SUPERFAMILY SSF54211 221 393 3.6E-60 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 SMART SM00433 36 798 5.1E-260 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 SMART SM00387 32 176 1.6E-28 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 734 794 5.2E-30 T 22-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 Pfam PF00204 DNA gyrase B 221 391 5.2E-60 T 22-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 Pfam PF01751 Toprim domain 420 532 1.4E-17 T 22-04-2016 IPR006171 Toprim domain TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PANTHER PTHR10169 2 554 4.4E-304 T 22-04-2016 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PANTHER PTHR10169 723 805 4.4E-304 T 22-04-2016 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 174 9.1E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR00418 DNA topoisomerase II family signature 737 753 3.3E-71 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR00418 DNA topoisomerase II family signature 114 128 3.3E-71 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR00418 DNA topoisomerase II family signature 506 523 3.3E-71 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR00418 DNA topoisomerase II family signature 269 282 3.3E-71 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR00418 DNA topoisomerase II family signature 526 538 3.3E-71 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR00418 DNA topoisomerase II family signature 488 504 3.3E-71 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR00418 DNA topoisomerase II family signature 71 84 3.3E-71 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR00418 DNA topoisomerase II family signature 36 51 3.3E-71 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR00418 DNA topoisomerase II family signature 421 435 3.3E-71 T 22-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 Gene3D G3DSA:3.30.565.10 16 218 3.5E-87 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR01159 DNA gyrase subunit B signature 361 375 6.9E-86 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR01159 DNA gyrase subunit B signature 774 790 6.9E-86 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR01159 DNA gyrase subunit B signature 375 395 6.9E-86 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR01159 DNA gyrase subunit B signature 6 16 6.9E-86 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR01159 DNA gyrase subunit B signature 471 480 6.9E-86 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR01159 DNA gyrase subunit B signature 758 770 6.9E-86 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR01159 DNA gyrase subunit B signature 243 261 6.9E-86 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR01159 DNA gyrase subunit B signature 196 209 6.9E-86 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR01159 DNA gyrase subunit B signature 313 329 6.9E-86 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR01159 DNA gyrase subunit B signature 220 242 6.9E-86 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 PRINTS PR01159 DNA gyrase subunit B signature 181 196 6.9E-86 T 22-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 3 805 104.918 T 22-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 Gene3D G3DSA:3.30.230.10 220 393 7.1E-78 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 ProSitePatterns PS00177 DNA topoisomerase II signature. 423 431 - T 22-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 6 805 2.1E-304 T 22-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 Gene3D G3DSA:3.40.50.670 405 551 5.0E-99 T 22-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00020 49b083c850eeec3ac99a21f95f85c153 805 Gene3D G3DSA:3.40.50.670 719 787 5.0E-99 T 22-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 TOLA_RS00905 5f5533917153731809d090e7366c4067 422 PANTHER PTHR11808 5 234 1.9E-238 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS00905 5f5533917153731809d090e7366c4067 422 PANTHER PTHR11808 264 422 1.9E-238 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS00905 5f5533917153731809d090e7366c4067 422 SUPERFAMILY SSF53383 1 421 7.5E-127 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS00905 5f5533917153731809d090e7366c4067 422 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS00905 5f5533917153731809d090e7366c4067 422 PIRSF PIRSF001434 1 422 2.3E-131 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS00905 5f5533917153731809d090e7366c4067 422 Gene3D G3DSA:3.40.640.10 2 285 1.4E-117 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS00905 5f5533917153731809d090e7366c4067 422 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 421 4.1E-142 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS00905 5f5533917153731809d090e7366c4067 422 PANTHER PTHR11808:SF12 5 234 1.9E-238 T 22-04-2016 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 TOLA_RS00905 5f5533917153731809d090e7366c4067 422 PANTHER PTHR11808:SF12 264 422 1.9E-238 T 22-04-2016 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 TOLA_RS00905 5f5533917153731809d090e7366c4067 422 Gene3D G3DSA:3.90.1150.10 287 421 5.9E-52 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS00905 5f5533917153731809d090e7366c4067 422 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 4 421 2.0E-196 T 22-04-2016 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 TOLA_RS10635 de9a7f1732f920f4a343c7fc82a5dcfa 633 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 164 247 4.5E-32 T 22-04-2016 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 TOLA_RS10635 de9a7f1732f920f4a343c7fc82a5dcfa 633 Pfam PF02378 Phosphotransferase system, EIIC 289 565 1.6E-10 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS10635 de9a7f1732f920f4a343c7fc82a5dcfa 633 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 274 617 5.4E-85 T 22-04-2016 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 TOLA_RS10635 de9a7f1732f920f4a343c7fc82a5dcfa 633 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 166 254 1.4E-18 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS10635 de9a7f1732f920f4a343c7fc82a5dcfa 633 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 5 130 1.4E-37 T 22-04-2016 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS10635 de9a7f1732f920f4a343c7fc82a5dcfa 633 SUPERFAMILY SSF55804 1 146 1.07E-35 T 22-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 TOLA_RS10635 de9a7f1732f920f4a343c7fc82a5dcfa 633 SUPERFAMILY SSF52794 163 259 7.32E-36 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS10635 de9a7f1732f920f4a343c7fc82a5dcfa 633 PANTHER PTHR30505:SF1 42 589 9.2E-299 T 22-04-2016 TOLA_RS10635 de9a7f1732f920f4a343c7fc82a5dcfa 633 Gene3D G3DSA:3.40.50.2300 159 260 3.1E-41 T 22-04-2016 TOLA_RS10635 de9a7f1732f920f4a343c7fc82a5dcfa 633 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 146 2.3E-32 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS10635 de9a7f1732f920f4a343c7fc82a5dcfa 633 Gene3D G3DSA:3.40.930.10 1 147 8.6E-46 T 22-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS10635 de9a7f1732f920f4a343c7fc82a5dcfa 633 PANTHER PTHR30505 42 589 9.2E-299 T 22-04-2016 TOLA_RS02935 711d625f7d7b6b227a94f431d126ac04 218 PANTHER PTHR33594:SF1 1 218 1.3E-51 T 22-04-2016 TOLA_RS02935 711d625f7d7b6b227a94f431d126ac04 218 SUPERFAMILY SSF109604 10 218 1.37E-60 T 22-04-2016 TOLA_RS02935 711d625f7d7b6b227a94f431d126ac04 218 PANTHER PTHR33594 1 218 1.3E-51 T 22-04-2016 TOLA_RS02935 711d625f7d7b6b227a94f431d126ac04 218 Gene3D G3DSA:1.10.3210.10 9 151 2.2E-40 T 22-04-2016 IPR006674 HD domain TOLA_RS02935 711d625f7d7b6b227a94f431d126ac04 218 Gene3D G3DSA:1.10.3210.10 190 218 2.2E-40 T 22-04-2016 IPR006674 HD domain TOLA_RS02935 711d625f7d7b6b227a94f431d126ac04 218 SMART SM00471 28 147 3.4E-10 T 22-04-2016 IPR003607 HD/PDEase domain TOLA_RS02935 711d625f7d7b6b227a94f431d126ac04 218 Pfam PF01966 HD domain 34 137 2.9E-13 T 22-04-2016 IPR006674 HD domain TOLA_RS07195 760983dbb0fdbb011dc67272fdc80d15 490 ProDom PD339107 ALGINATE ALG8 BIOSYNTHESIS TRANSFERASE TRANSMEMBRANE MEMBRANE 2.4.1.- GLYCOSYL GLYCOSYLTRANSFERASE PRECURSOR 8 475 0.0 T 22-04-2016 TOLA_RS07195 760983dbb0fdbb011dc67272fdc80d15 490 Pfam PF13641 Glycosyltransferase like family 2 82 339 4.3E-62 T 22-04-2016 TOLA_RS07195 760983dbb0fdbb011dc67272fdc80d15 490 SUPERFAMILY SSF53448 148 403 8.53E-12 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS01110 66a9be5c020d314778414dbd07ad7d89 244 Gene3D G3DSA:3.60.40.10 12 242 8.8E-56 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TOLA_RS01110 66a9be5c020d314778414dbd07ad7d89 244 SUPERFAMILY SSF81606 11 242 4.84E-56 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TOLA_RS01110 66a9be5c020d314778414dbd07ad7d89 244 SMART SM00332 2 241 5.8E-20 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TOLA_RS01110 66a9be5c020d314778414dbd07ad7d89 244 PANTHER PTHR13832 13 242 2.8E-29 T 22-04-2016 IPR015655 Protein phosphatase 2C family GO:0004722|GO:0006470 KEGG: 04660+3.1.3.16 TOLA_RS01110 66a9be5c020d314778414dbd07ad7d89 244 SMART SM00331 12 243 2.3E-21 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TOLA_RS01110 66a9be5c020d314778414dbd07ad7d89 244 PANTHER PTHR13832:SF226 13 242 2.8E-29 T 22-04-2016 TOLA_RS01110 66a9be5c020d314778414dbd07ad7d89 244 Pfam PF13672 Protein phosphatase 2C 18 203 8.8E-11 T 22-04-2016 TOLA_RS10965 b622d7332506bd63da0812b9a4bd20d0 327 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 27 319 3.4E-80 T 22-04-2016 IPR001761 Periplasmic binding protein/LacI sugar binding domain TOLA_RS10965 b622d7332506bd63da0812b9a4bd20d0 327 PIRSF PIRSF002816 2 327 2.1E-148 T 22-04-2016 IPR026266 L-arabinose-binding periplasmic protein GO:0042882 TOLA_RS10965 b622d7332506bd63da0812b9a4bd20d0 327 Gene3D G3DSA:3.40.50.2300 149 296 3.4E-49 T 22-04-2016 TOLA_RS10965 b622d7332506bd63da0812b9a4bd20d0 327 PANTHER PTHR30036:SF1 1 327 8.0E-97 T 22-04-2016 TOLA_RS10965 b622d7332506bd63da0812b9a4bd20d0 327 PANTHER PTHR30036 1 327 8.0E-97 T 22-04-2016 TOLA_RS10965 b622d7332506bd63da0812b9a4bd20d0 327 Gene3D G3DSA:3.40.50.2300 26 148 3.8E-41 T 22-04-2016 TOLA_RS10965 b622d7332506bd63da0812b9a4bd20d0 327 SUPERFAMILY SSF53822 26 324 2.16E-64 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS14810 28334ae96c98e995534f957c98671ce2 473 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 13 447 3.3E-135 T 22-04-2016 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 TOLA_RS14810 28334ae96c98e995534f957c98671ce2 473 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 63 88 - T 22-04-2016 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 TOLA_RS14810 28334ae96c98e995534f957c98671ce2 473 PANTHER PTHR11328:SF35 7 448 2.1E-171 T 22-04-2016 TOLA_RS14810 28334ae96c98e995534f957c98671ce2 473 PANTHER PTHR11328 7 448 2.1E-171 T 22-04-2016 TOLA_RS14810 28334ae96c98e995534f957c98671ce2 473 Gene3D G3DSA:1.20.1250.20 10 213 8.7E-13 T 22-04-2016 TOLA_RS14810 28334ae96c98e995534f957c98671ce2 473 Gene3D G3DSA:1.20.1250.20 229 437 1.7E-16 T 22-04-2016 TOLA_RS14810 28334ae96c98e995534f957c98671ce2 473 SUPERFAMILY SSF103473 6 437 7.32E-39 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS14810 28334ae96c98e995534f957c98671ce2 473 Pfam PF13347 MFS/sugar transport protein 14 434 5.5E-99 T 22-04-2016 TOLA_RS07035 0caa428ecb0d2acd8d5aa054aa7010c3 333 Gene3D G3DSA:3.40.190.10 259 326 2.7E-52 T 22-04-2016 TOLA_RS07035 0caa428ecb0d2acd8d5aa054aa7010c3 333 Gene3D G3DSA:3.40.190.10 33 116 2.7E-52 T 22-04-2016 TOLA_RS07035 0caa428ecb0d2acd8d5aa054aa7010c3 333 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 21 327 1.2E-93 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family TOLA_RS07035 0caa428ecb0d2acd8d5aa054aa7010c3 333 Pfam PF16868 NMT1-like family 38 325 6.7E-89 T 22-04-2016 IPR011852 TRAP transporter solute receptor, TAXI family TOLA_RS07035 0caa428ecb0d2acd8d5aa054aa7010c3 333 Gene3D G3DSA:3.40.190.10 125 258 1.5E-32 T 22-04-2016 TOLA_RS07035 0caa428ecb0d2acd8d5aa054aa7010c3 333 PANTHER PTHR30024:SF13 1 328 2.6E-79 T 22-04-2016 TOLA_RS07035 0caa428ecb0d2acd8d5aa054aa7010c3 333 PANTHER PTHR30024 1 328 2.6E-79 T 22-04-2016 TOLA_RS07035 0caa428ecb0d2acd8d5aa054aa7010c3 333 SUPERFAMILY SSF53850 33 327 2.7E-73 T 22-04-2016 TOLA_RS03475 906df0de7a196d9b25fe51582e6344e4 316 PANTHER PTHR30472 15 316 7.7E-106 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 TOLA_RS03475 906df0de7a196d9b25fe51582e6344e4 316 PANTHER PTHR30472:SF19 15 316 7.7E-106 T 22-04-2016 TOLA_RS03475 906df0de7a196d9b25fe51582e6344e4 316 SUPERFAMILY SSF81345 7 313 4.71E-53 T 22-04-2016 IPR029022 ABC transporter, BtuC-like TOLA_RS03475 906df0de7a196d9b25fe51582e6344e4 316 Pfam PF01032 FecCD transport family 25 312 7.7E-54 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 TOLA_RS03475 906df0de7a196d9b25fe51582e6344e4 316 Gene3D G3DSA:1.10.3470.10 20 314 8.0E-58 T 22-04-2016 IPR029022 ABC transporter, BtuC-like TOLA_RS00250 324e9d28426f28c7130179298ec1f0f6 811 PANTHER PTHR11468 17 807 0.0 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 TOLA_RS00250 324e9d28426f28c7130179298ec1f0f6 811 Gene3D G3DSA:3.40.50.2000 14 477 7.8E-181 T 22-04-2016 TOLA_RS00250 324e9d28426f28c7130179298ec1f0f6 811 PIRSF PIRSF000460 3 810 4.1E-202 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 TOLA_RS00250 324e9d28426f28c7130179298ec1f0f6 811 Pfam PF00343 Carbohydrate phosphorylase 104 808 0.0 T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 TOLA_RS00250 324e9d28426f28c7130179298ec1f0f6 811 Gene3D G3DSA:3.40.50.2000 478 794 3.4E-133 T 22-04-2016 TOLA_RS00250 324e9d28426f28c7130179298ec1f0f6 811 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 16 808 0.0 T 22-04-2016 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 TOLA_RS00250 324e9d28426f28c7130179298ec1f0f6 811 PANTHER PTHR11468:SF10 17 807 0.0 T 22-04-2016 TOLA_RS00250 324e9d28426f28c7130179298ec1f0f6 811 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 653 665 - T 22-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 TOLA_RS00250 324e9d28426f28c7130179298ec1f0f6 811 SUPERFAMILY SSF53756 14 809 2.59E-293 T 22-04-2016 TOLA_RS07045 906e8ce983682a674f68043a023e5fdd 389 SUPERFAMILY SSF103473 17 386 3.4E-47 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS07045 906e8ce983682a674f68043a023e5fdd 389 Pfam PF07690 Major Facilitator Superfamily 19 353 2.6E-32 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS07045 906e8ce983682a674f68043a023e5fdd 389 PANTHER PTHR23535:SF2 1 389 9.1E-131 T 22-04-2016 TOLA_RS07045 906e8ce983682a674f68043a023e5fdd 389 Gene3D G3DSA:1.20.1250.20 211 386 1.8E-21 T 22-04-2016 TOLA_RS07045 906e8ce983682a674f68043a023e5fdd 389 Gene3D G3DSA:1.20.1250.20 17 195 2.6E-18 T 22-04-2016 TOLA_RS07045 906e8ce983682a674f68043a023e5fdd 389 PANTHER PTHR23535 1 389 9.1E-131 T 22-04-2016 TOLA_RS13740 44dc065b5b7049324866d6c8c93fc1e3 353 Hamap MF_00567 Quinolinate synthase A [nadA]. 1 347 65.74 T 22-04-2016 IPR023513 Quinolinate synthase A, type 1 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 TOLA_RS13740 44dc065b5b7049324866d6c8c93fc1e3 353 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 26 341 1.2E-117 T 22-04-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 TOLA_RS13740 44dc065b5b7049324866d6c8c93fc1e3 353 PANTHER PTHR30573 1 346 6.2E-156 T 22-04-2016 TOLA_RS13740 44dc065b5b7049324866d6c8c93fc1e3 353 Pfam PF02445 Quinolinate synthetase A protein 32 340 1.9E-105 T 22-04-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 TOLA_RS13740 44dc065b5b7049324866d6c8c93fc1e3 353 SUPERFAMILY SSF142754 28 341 4.84E-108 T 22-04-2016 TOLA_RS12870 7f6393dd7da2f5adff7b912f031cf78a 152 Gene3D G3DSA:3.40.50.9100 5 147 4.8E-68 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 TOLA_RS12870 7f6393dd7da2f5adff7b912f031cf78a 152 ProSitePatterns PS01029 Dehydroquinase class II signature. 10 27 - T 22-04-2016 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 TOLA_RS12870 7f6393dd7da2f5adff7b912f031cf78a 152 PANTHER PTHR21272 2 152 1.3E-93 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 TOLA_RS12870 7f6393dd7da2f5adff7b912f031cf78a 152 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 152 75.545 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 TOLA_RS12870 7f6393dd7da2f5adff7b912f031cf78a 152 SUPERFAMILY SSF52304 6 148 4.71E-63 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 TOLA_RS12870 7f6393dd7da2f5adff7b912f031cf78a 152 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 6 145 6.2E-65 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 TOLA_RS12870 7f6393dd7da2f5adff7b912f031cf78a 152 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 20 143 1.0E-54 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 TOLA_RS12870 7f6393dd7da2f5adff7b912f031cf78a 152 Pfam PF01220 Dehydroquinase class II 6 142 1.6E-59 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 TOLA_RS12870 7f6393dd7da2f5adff7b912f031cf78a 152 PIRSF PIRSF001399 3 149 3.1E-60 T 22-04-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 TOLA_RS03090 9ad5fd8795dfe538daf35dd0ddb2a4a9 642 SUPERFAMILY SSF52540 77 364 4.68E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03090 9ad5fd8795dfe538daf35dd0ddb2a4a9 642 Pfam PF00271 Helicase conserved C-terminal domain 234 342 1.3E-28 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS03090 9ad5fd8795dfe538daf35dd0ddb2a4a9 642 Gene3D G3DSA:3.40.50.300 4 208 1.6E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03090 9ad5fd8795dfe538daf35dd0ddb2a4a9 642 SMART SM00490 261 342 3.1E-34 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS03090 9ad5fd8795dfe538daf35dd0ddb2a4a9 642 PANTHER PTHR24031 5 522 3.3E-227 T 22-04-2016 TOLA_RS03090 9ad5fd8795dfe538daf35dd0ddb2a4a9 642 PANTHER PTHR24031:SF261 5 522 3.3E-227 T 22-04-2016 TOLA_RS03090 9ad5fd8795dfe538daf35dd0ddb2a4a9 642 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 3 572 45.135 T 22-04-2016 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 TOLA_RS03090 9ad5fd8795dfe538daf35dd0ddb2a4a9 642 Pfam PF00270 DEAD/DEAH box helicase 33 198 3.8E-49 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS03090 9ad5fd8795dfe538daf35dd0ddb2a4a9 642 Gene3D G3DSA:3.40.50.300 209 378 6.4E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03090 9ad5fd8795dfe538daf35dd0ddb2a4a9 642 Pfam PF03880 DbpA RNA binding domain 500 570 1.8E-22 T 22-04-2016 IPR005580 DbpA, RNA-binding domain TOLA_RS03090 9ad5fd8795dfe538daf35dd0ddb2a4a9 642 SMART SM00487 27 225 2.6E-59 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS03090 9ad5fd8795dfe538daf35dd0ddb2a4a9 642 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 156 164 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TOLA_RS07945 a5e475a55b2edef190a854eac9a532da 230 Pfam PF02224 Cytidylate kinase 10 223 8.2E-73 T 22-04-2016 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 TOLA_RS07945 a5e475a55b2edef190a854eac9a532da 230 TIGRFAM TIGR00017 cmk: cytidylate kinase 8 221 3.5E-78 T 22-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 TOLA_RS07945 a5e475a55b2edef190a854eac9a532da 230 SUPERFAMILY SSF52540 8 225 1.22E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07945 a5e475a55b2edef190a854eac9a532da 230 Gene3D G3DSA:3.40.50.300 8 223 5.8E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07945 a5e475a55b2edef190a854eac9a532da 230 PANTHER PTHR21299 8 227 4.7E-73 T 22-04-2016 TOLA_RS07945 a5e475a55b2edef190a854eac9a532da 230 Hamap MF_00238 Cytidylate kinase [cmk]. 8 226 33.383 T 22-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 TOLA_RS06165 6d168163c68f4b3af3c83ca952009e7a 140 SUPERFAMILY SSF46785 4 131 3.51E-43 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06165 6d168163c68f4b3af3c83ca952009e7a 140 PANTHER PTHR33202 3 140 2.9E-40 T 22-04-2016 TOLA_RS06165 6d168163c68f4b3af3c83ca952009e7a 140 Pfam PF01475 Ferric uptake regulator family 9 127 2.2E-42 T 22-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TOLA_RS06165 6d168163c68f4b3af3c83ca952009e7a 140 Gene3D G3DSA:1.10.10.10 3 80 6.1E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10475 4bc2a530c89e870f911fb25d3aa8e0fe 548 PANTHER PTHR30425 188 546 9.4E-244 T 22-04-2016 TOLA_RS10475 4bc2a530c89e870f911fb25d3aa8e0fe 548 SUPERFAMILY SSF161098 274 530 5.89E-35 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10475 4bc2a530c89e870f911fb25d3aa8e0fe 548 PANTHER PTHR30425:SF7 188 546 9.4E-244 T 22-04-2016 TOLA_RS10475 4bc2a530c89e870f911fb25d3aa8e0fe 548 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 316 541 1.3E-16 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10475 4bc2a530c89e870f911fb25d3aa8e0fe 548 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 280 540 7.8E-75 T 22-04-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 TOLA_RS10475 4bc2a530c89e870f911fb25d3aa8e0fe 548 Gene3D G3DSA:1.10.3720.10 27 43 8.5E-49 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10475 4bc2a530c89e870f911fb25d3aa8e0fe 548 Gene3D G3DSA:1.10.3720.10 283 544 8.5E-49 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 PANTHER PTHR21060:SF15 2 397 1.1E-265 T 22-04-2016 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 TIGRFAM TIGR00016 ackA: acetate kinase 1 397 2.1E-173 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 SUPERFAMILY SSF53067 158 396 2.11E-85 T 22-04-2016 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 PRINTS PR00471 Acetate kinase family signature 174 187 7.5E-46 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 PRINTS PR00471 Acetate kinase family signature 323 339 7.5E-46 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 PRINTS PR00471 Acetate kinase family signature 378 390 7.5E-46 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 PRINTS PR00471 Acetate kinase family signature 300 313 7.5E-46 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 PRINTS PR00471 Acetate kinase family signature 6 17 7.5E-46 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 PRINTS PR00471 Acetate kinase family signature 204 225 7.5E-46 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 22-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 204 221 - T 22-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 SUPERFAMILY SSF53067 4 197 3.75E-65 T 22-04-2016 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 Gene3D G3DSA:3.30.420.40 5 205 3.4E-10 T 22-04-2016 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 Pfam PF00871 Acetokinase family 6 391 1.6E-167 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 PIRSF PIRSF000722 2 398 2.7E-147 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 Hamap MF_00020 Acetate kinase [ackA]. 1 398 186.502 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 PANTHER PTHR21060 2 397 1.1E-265 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS04505 9bd7f8f0f6fe47073fb4d267bcf33f26 398 Gene3D G3DSA:3.30.420.40 206 396 2.2E-75 T 22-04-2016 TOLA_RS00975 46d9d1c801392a041d4de9e1b32fb6c0 224 Gene3D G3DSA:1.10.150.20 47 78 7.4E-4 T 22-04-2016 TOLA_RS00975 46d9d1c801392a041d4de9e1b32fb6c0 224 Gene3D G3DSA:3.40.140.10 101 224 4.2E-48 T 22-04-2016 TOLA_RS00975 46d9d1c801392a041d4de9e1b32fb6c0 224 Pfam PF04002 RadC-like JAB domain 104 222 6.2E-43 T 22-04-2016 IPR025657 RadC-like JAB domain TOLA_RS00975 46d9d1c801392a041d4de9e1b32fb6c0 224 SUPERFAMILY SSF47781 17 90 3.71E-12 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 TOLA_RS00975 46d9d1c801392a041d4de9e1b32fb6c0 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 224 1.8E-74 T 22-04-2016 IPR001405 RadC protein TOLA_RS00975 46d9d1c801392a041d4de9e1b32fb6c0 224 PANTHER PTHR30471:SF5 1 224 5.6E-141 T 22-04-2016 TOLA_RS00975 46d9d1c801392a041d4de9e1b32fb6c0 224 PANTHER PTHR30471 1 224 5.6E-141 T 22-04-2016 TOLA_RS00975 46d9d1c801392a041d4de9e1b32fb6c0 224 SUPERFAMILY SSF102712 112 190 3.27E-7 T 22-04-2016 TOLA_RS00975 46d9d1c801392a041d4de9e1b32fb6c0 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 22-04-2016 IPR020891 Uncharacterised protein family UPF0758, conserved site TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 344 2.0E-63 T 22-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 Gene3D G3DSA:3.40.50.300 78 345 2.0E-108 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 75 6.4E-19 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 SMART SM00382 144 407 1.3E-4 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 SUPERFAMILY SSF52540 79 350 3.61E-90 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 462 56.406 T 22-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 335 344 - T 22-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 PANTHER PTHR15184 1 462 0.0 T 22-04-2016 TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 PANTHER PTHR15184:SF44 1 462 0.0 T 22-04-2016 TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 SUPERFAMILY SSF50615 1 76 7.06E-24 T 22-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 Gene3D G3DSA:1.10.1140.10 347 462 5.1E-58 T 22-04-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 462 3.1E-259 T 22-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 Gene3D G3DSA:2.40.10.170 2 76 9.1E-28 T 22-04-2016 TOLA_RS16075 4dfb7e9171a988d045ed1b0a25a8a1d3 462 SUPERFAMILY SSF47917 347 461 4.45E-54 T 22-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS03505 86f3f5cf3554ab87c6efaf72ccd0cd7a 364 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 246 265 - T 22-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 TOLA_RS03505 86f3f5cf3554ab87c6efaf72ccd0cd7a 364 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 5 345 7.1E-164 T 22-04-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 TOLA_RS03505 86f3f5cf3554ab87c6efaf72ccd0cd7a 364 Gene3D G3DSA:3.40.718.10 2 361 1.8E-128 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 TOLA_RS03505 86f3f5cf3554ab87c6efaf72ccd0cd7a 364 PANTHER PTHR11835 3 364 4.7E-201 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 TOLA_RS03505 86f3f5cf3554ab87c6efaf72ccd0cd7a 364 SMART SM01329 5 357 9.3E-194 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 TOLA_RS03505 86f3f5cf3554ab87c6efaf72ccd0cd7a 364 PANTHER PTHR11835:SF35 3 364 4.7E-201 T 22-04-2016 TOLA_RS03505 86f3f5cf3554ab87c6efaf72ccd0cd7a 364 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 4 361 50.578 T 22-04-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 TOLA_RS03505 86f3f5cf3554ab87c6efaf72ccd0cd7a 364 SUPERFAMILY SSF53659 2 362 6.12E-121 T 22-04-2016 TOLA_RS03505 86f3f5cf3554ab87c6efaf72ccd0cd7a 364 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 357 9.1E-133 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 TOLA_RS08385 bd70ad3bedc8ff1db246cf9405e39145 97 PANTHER PTHR33336 1 95 4.0E-16 T 22-04-2016 TOLA_RS08385 bd70ad3bedc8ff1db246cf9405e39145 97 SUPERFAMILY SSF54909 1 93 1.65E-23 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel TOLA_RS08385 bd70ad3bedc8ff1db246cf9405e39145 97 Gene3D G3DSA:3.30.70.900 2 92 3.7E-25 T 22-04-2016 TOLA_RS08385 bd70ad3bedc8ff1db246cf9405e39145 97 PANTHER PTHR33336:SF5 1 95 4.0E-16 T 22-04-2016 TOLA_RS08385 bd70ad3bedc8ff1db246cf9405e39145 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 6 71 1.9E-14 T 22-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 SMART SM00345 11 70 6.9E-22 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 PANTHER PTHR11751 12 96 8.3E-53 T 22-04-2016 TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 70 1.9E-19 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 TIGRFAM TIGR02812 fadR_gamma: fatty acid metabolism transcriptional regulator FadR 1 231 1.3E-108 T 22-04-2016 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 Gene3D G3DSA:1.20.120.530 79 231 3.4E-51 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 SUPERFAMILY SSF48008 79 229 4.84E-53 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 Hamap MF_00696 Fatty acid metabolism regulator protein [fadR]. 1 237 133.512 T 22-04-2016 IPR014178 Fatty acid response transcription factor FadR GO:0000062|GO:0003677|GO:0003700|GO:0019217 TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 PANTHER PTHR11751:SF402 12 96 8.3E-53 T 22-04-2016 TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 Gene3D G3DSA:1.10.10.10 10 75 3.3E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 3.3E-9 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 3.3E-9 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 SUPERFAMILY SSF46785 10 74 2.34E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11285 bb770d9fedc11e710c42d25a8b31d691 237 Pfam PF07840 FadR C-terminal domain 71 232 1.9E-63 T 22-04-2016 IPR028374 FadR, C-terminal domain GO:0000062|GO:0019217 TOLA_RS07980 f80a47da4d76d88d026413bcd3f2726f 325 PANTHER PTHR38687 151 325 1.9E-24 T 22-04-2016 TOLA_RS07980 f80a47da4d76d88d026413bcd3f2726f 325 Pfam PF05036 Sporulation related domain 248 308 8.3E-12 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 TOLA_RS07980 f80a47da4d76d88d026413bcd3f2726f 325 PANTHER PTHR38687 2 107 1.9E-24 T 22-04-2016 TOLA_RS07980 f80a47da4d76d88d026413bcd3f2726f 325 PANTHER PTHR38687:SF1 2 107 1.9E-24 T 22-04-2016 TOLA_RS07980 f80a47da4d76d88d026413bcd3f2726f 325 Gene3D G3DSA:3.30.70.1070 247 318 1.3E-17 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 TOLA_RS07980 f80a47da4d76d88d026413bcd3f2726f 325 PANTHER PTHR38687:SF1 151 325 1.9E-24 T 22-04-2016 TOLA_RS07980 f80a47da4d76d88d026413bcd3f2726f 325 SUPERFAMILY SSF110997 247 317 7.06E-16 T 22-04-2016 IPR007730 Sporulation-related domain GO:0042834 TOLA_RS10305 ce608ce51356bd9f443a6a15653a41b5 314 PANTHER PTHR30081 11 313 2.3E-86 T 22-04-2016 TOLA_RS10305 ce608ce51356bd9f443a6a15653a41b5 314 SUPERFAMILY SSF82866 76 292 5.23E-40 T 22-04-2016 TOLA_RS10305 ce608ce51356bd9f443a6a15653a41b5 314 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 39 284 2.1E-83 T 22-04-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 TOLA_RS10305 ce608ce51356bd9f443a6a15653a41b5 314 Gene3D G3DSA:1.20.1640.10 127 293 7.5E-26 T 22-04-2016 TOLA_RS10305 ce608ce51356bd9f443a6a15653a41b5 314 Pfam PF02355 Protein export membrane protein 112 292 4.6E-68 T 22-04-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TOLA_RS10305 ce608ce51356bd9f443a6a15653a41b5 314 PRINTS PR01755 Bacterial translocase SecF protein signature 38 53 1.6E-31 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TOLA_RS10305 ce608ce51356bd9f443a6a15653a41b5 314 PRINTS PR01755 Bacterial translocase SecF protein signature 152 166 1.6E-31 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TOLA_RS10305 ce608ce51356bd9f443a6a15653a41b5 314 PRINTS PR01755 Bacterial translocase SecF protein signature 232 247 1.6E-31 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TOLA_RS10305 ce608ce51356bd9f443a6a15653a41b5 314 PRINTS PR01755 Bacterial translocase SecF protein signature 200 218 1.6E-31 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TOLA_RS10305 ce608ce51356bd9f443a6a15653a41b5 314 Pfam PF07549 SecD/SecF GG Motif 35 60 2.5E-11 T 22-04-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site TOLA_RS10305 ce608ce51356bd9f443a6a15653a41b5 314 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 11 295 28.621 T 22-04-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 TOLA_RS10305 ce608ce51356bd9f443a6a15653a41b5 314 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 116 281 3.3E-56 T 22-04-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TOLA_RS09090 560b944d6f465e7c913c100dfd44f35f 382 Gene3D G3DSA:3.40.50.1970 9 184 4.1E-55 T 22-04-2016 TOLA_RS09090 560b944d6f465e7c913c100dfd44f35f 382 Gene3D G3DSA:1.20.1090.10 187 382 7.9E-43 T 22-04-2016 TOLA_RS09090 560b944d6f465e7c913c100dfd44f35f 382 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 359 3.4E-91 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 TOLA_RS09090 560b944d6f465e7c913c100dfd44f35f 382 SUPERFAMILY SSF56796 2 381 2.36E-99 T 22-04-2016 TOLA_RS09090 560b944d6f465e7c913c100dfd44f35f 382 PANTHER PTHR11496 1 382 4.3E-96 T 22-04-2016 TOLA_RS08980 8bacda34d3a75d9b03c8a90f4541945b 305 Pfam PF03466 LysR substrate binding domain 91 295 5.9E-41 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS08980 8bacda34d3a75d9b03c8a90f4541945b 305 PANTHER PTHR30537 1 301 4.3E-93 T 22-04-2016 TOLA_RS08980 8bacda34d3a75d9b03c8a90f4541945b 305 PANTHER PTHR30537:SF5 1 301 4.3E-93 T 22-04-2016 TOLA_RS08980 8bacda34d3a75d9b03c8a90f4541945b 305 Gene3D G3DSA:3.40.190.10 180 262 2.1E-7 T 22-04-2016 TOLA_RS08980 8bacda34d3a75d9b03c8a90f4541945b 305 SUPERFAMILY SSF46785 5 85 6.53E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08980 8bacda34d3a75d9b03c8a90f4541945b 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 2.9E-15 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS08980 8bacda34d3a75d9b03c8a90f4541945b 305 SUPERFAMILY SSF53850 90 297 1.99E-41 T 22-04-2016 TOLA_RS08980 8bacda34d3a75d9b03c8a90f4541945b 305 Gene3D G3DSA:1.10.10.10 6 86 8.8E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08980 8bacda34d3a75d9b03c8a90f4541945b 305 Gene3D G3DSA:3.40.190.10 94 179 2.1E-20 T 22-04-2016 TOLA_RS12550 42f522c1f258e3220836ee26c7448fe0 376 PANTHER PTHR30294 4 375 4.1E-220 T 22-04-2016 TOLA_RS12550 42f522c1f258e3220836ee26c7448fe0 376 Pfam PF12698 ABC-2 family transporter protein 28 365 3.1E-35 T 22-04-2016 TOLA_RS12550 42f522c1f258e3220836ee26c7448fe0 376 PANTHER PTHR30294:SF22 4 375 4.1E-220 T 22-04-2016 TOLA_RS08400 1e7ecf5b8a3baca150db6babcf03d687 337 PANTHER PTHR30344:SF1 137 333 2.7E-38 T 22-04-2016 TOLA_RS08400 1e7ecf5b8a3baca150db6babcf03d687 337 Gene3D G3DSA:2.130.10.10 11 334 2.5E-41 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 TOLA_RS08400 1e7ecf5b8a3baca150db6babcf03d687 337 Pfam PF10282 Lactonase, 7-bladed beta-propeller 13 333 1.9E-46 T 22-04-2016 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31|UniPathway: UPA00115 TOLA_RS08400 1e7ecf5b8a3baca150db6babcf03d687 337 SUPERFAMILY SSF50974 136 317 5.75E-22 T 22-04-2016 IPR011045 Nitrous oxide reductase, N-terminal TOLA_RS08400 1e7ecf5b8a3baca150db6babcf03d687 337 PANTHER PTHR30344 137 333 2.7E-38 T 22-04-2016 TOLA_RS08585 75b89469748c09914e9e68f209ea58b1 172 PIRSF PIRSF018505 1 172 6.6E-74 T 22-04-2016 IPR003207 Propanediol/glycerol dehydratase, small subunit KEGG: 00640+4.2.1.28|MetaCyc: PWY-7013|UniPathway: UPA00621 TOLA_RS08585 75b89469748c09914e9e68f209ea58b1 172 SUPERFAMILY SSF47148 38 172 3.27E-62 T 22-04-2016 IPR003207 Propanediol/glycerol dehydratase, small subunit KEGG: 00640+4.2.1.28|MetaCyc: PWY-7013|UniPathway: UPA00621 TOLA_RS08585 75b89469748c09914e9e68f209ea58b1 172 Pfam PF02287 Dehydratase small subunit 38 169 2.2E-62 T 22-04-2016 IPR003207 Propanediol/glycerol dehydratase, small subunit KEGG: 00640+4.2.1.28|MetaCyc: PWY-7013|UniPathway: UPA00621 TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 PANTHER PTHR32305:SF6 407 662 2.7E-36 T 22-04-2016 TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 PANTHER PTHR32305:SF6 257 383 2.7E-36 T 22-04-2016 TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 PANTHER PTHR32305:SF6 1 233 2.7E-36 T 22-04-2016 TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 576 651 1.4E-20 T 22-04-2016 IPR022385 Rhs repeat-associated core GO:0097264 TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 97 127 1.2E-8 T 22-04-2016 IPR006530 YD repeat TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 3 40 2.8E-9 T 22-04-2016 IPR006530 YD repeat TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 108 149 9.1E-9 T 22-04-2016 IPR006530 YD repeat TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 153 187 2.3E-7 T 22-04-2016 IPR006530 YD repeat TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 PANTHER PTHR32305 407 662 2.7E-36 T 22-04-2016 TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 PANTHER PTHR32305 257 383 2.7E-36 T 22-04-2016 TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 PANTHER PTHR32305 1 233 2.7E-36 T 22-04-2016 TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 Pfam PF05593 RHS Repeat 3 39 1.5E-8 T 22-04-2016 IPR031325 RHS repeat TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 Pfam PF05593 RHS Repeat 95 123 1.9E-5 T 22-04-2016 IPR031325 RHS repeat TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 Pfam PF05593 RHS Repeat 265 299 1.0E-5 T 22-04-2016 IPR031325 RHS repeat TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 Pfam PF05593 RHS Repeat 154 186 2.7E-5 T 22-04-2016 IPR031325 RHS repeat TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 Pfam PF05593 RHS Repeat 129 165 5.1E-6 T 22-04-2016 IPR031325 RHS repeat TOLA_RS15790 a1af6918808cd37db9b95ee5fa7013e7 792 Pfam PF05593 RHS Repeat 46 82 1.4E-8 T 22-04-2016 IPR031325 RHS repeat TOLA_RS16315 80093b7b252715872dfc5d80fb049667 203 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 154 1.4E-27 T 22-04-2016 IPR007404 LexA-binding, inner membrane-associated putative hydrolase TOLA_RS16315 80093b7b252715872dfc5d80fb049667 203 PANTHER PTHR35531:SF1 34 164 4.6E-17 T 22-04-2016 TOLA_RS16315 80093b7b252715872dfc5d80fb049667 203 PANTHER PTHR35531 34 164 4.6E-17 T 22-04-2016 TOLA_RS06950 ffc1f73a35111594780b91ceb54054e5 325 Pfam PF09614 CRISPR-associated protein (Cas_Csy2) 5 306 5.2E-106 T 22-04-2016 IPR013398 CRISPR-associated protein Csy2 TOLA_RS06950 ffc1f73a35111594780b91ceb54054e5 325 TIGRFAM TIGR02565 cas_Csy2: CRISPR type I-F/YPEST-associated protein Csy2 4 306 2.4E-94 T 22-04-2016 IPR013398 CRISPR-associated protein Csy2 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 SUPERFAMILY SSF47226 764 895 4.71E-17 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 Pfam PF09984 Uncharacterised signal transduction histidine kinase domain (DUF2222) 31 174 1.5E-52 T 22-04-2016 IPR019247 Histidine kinase BarA, N-terminal TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 Gene3D G3DSA:1.10.287.130 282 351 1.2E-18 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 Pfam PF00512 His Kinase A (phospho-acceptor) domain 291 355 2.0E-19 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 SMART SM00304 198 250 1.4E-6 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 SUPERFAMILY SSF158472 200 248 3.4E-5 T 22-04-2016 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 402 518 8.8E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 Gene3D G3DSA:3.30.565.10 356 523 1.6E-47 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 Pfam PF01627 Hpt domain 815 891 2.3E-7 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 SUPERFAMILY SSF55874 344 521 6.02E-47 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 SUPERFAMILY SSF47384 275 356 1.06E-21 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 SMART SM00388 290 355 7.5E-24 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 Pfam PF00072 Response regulator receiver domain 670 779 3.9E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 Gene3D G3DSA:3.40.50.2300 667 774 5.3E-37 T 22-04-2016 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 SUPERFAMILY SSF52172 667 794 1.85E-33 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 PANTHER PTHR24423:SF540 6 13 3.3E-150 T 22-04-2016 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 PANTHER PTHR24423:SF540 192 230 3.3E-150 T 22-04-2016 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 PANTHER PTHR24423:SF540 269 522 3.3E-150 T 22-04-2016 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 PANTHER PTHR24423:SF540 612 824 3.3E-150 T 22-04-2016 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 Pfam PF00672 HAMP domain 179 246 1.0E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 472 1.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 458 1.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 516 1.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 497 1.0E-16 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 SMART SM00448 668 781 7.8E-33 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 SMART SM00073 806 904 0.0037 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 SMART SM00387 402 519 8.5E-39 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 PANTHER PTHR24423 6 13 3.3E-150 T 22-04-2016 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 PANTHER PTHR24423 192 230 3.3E-150 T 22-04-2016 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 PANTHER PTHR24423 269 522 3.3E-150 T 22-04-2016 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 PANTHER PTHR24423 612 824 3.3E-150 T 22-04-2016 TOLA_RS14040 a5eac86652109defcee0bda6831ba633 908 Gene3D G3DSA:1.20.120.160 775 906 1.2E-13 T 22-04-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 TOLA_RS13435 ed690b762fb4cd1e0ce79ec583ef0121 135 PANTHER PTHR11058 10 123 2.0E-61 T 22-04-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 TOLA_RS13435 ed690b762fb4cd1e0ce79ec583ef0121 135 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 3 120 20.335 T 22-04-2016 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 TOLA_RS13435 ed690b762fb4cd1e0ce79ec583ef0121 135 PANTHER PTHR11058:SF5 10 123 2.0E-61 T 22-04-2016 TOLA_RS13435 ed690b762fb4cd1e0ce79ec583ef0121 135 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 23 119 1.4E-33 T 22-04-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 TOLA_RS08565 146efc7ba92548815830dcdb33e62e86 94 SUPERFAMILY SSF143414 4 90 4.05E-32 T 22-04-2016 TOLA_RS08565 146efc7ba92548815830dcdb33e62e86 94 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 1 50 6.0E-20 T 22-04-2016 TOLA_RS08565 146efc7ba92548815830dcdb33e62e86 94 PANTHER PTHR33941 1 93 9.7E-42 T 22-04-2016 TOLA_RS08565 146efc7ba92548815830dcdb33e62e86 94 Pfam PF00936 BMC domain 5 80 1.6E-29 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08565 146efc7ba92548815830dcdb33e62e86 94 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 22 41 - T 22-04-2016 IPR020808 Bacterial microcompartments protein, conserved site TOLA_RS08565 146efc7ba92548815830dcdb33e62e86 94 SMART SM00877 4 80 1.1E-35 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS03590 1c662793bc459be58586a1c7af03d0b4 186 Pfam PF00782 Dual specificity phosphatase, catalytic domain 84 174 2.7E-8 T 22-04-2016 IPR000340 Dual specificity phosphatase, catalytic domain GO:0006470|GO:0008138 TOLA_RS03590 1c662793bc459be58586a1c7af03d0b4 186 SUPERFAMILY SSF52799 39 178 5.85E-33 T 22-04-2016 IPR029021 Protein-tyrosine phosphatase-like TOLA_RS03590 1c662793bc459be58586a1c7af03d0b4 186 PANTHER PTHR23339:SF64 12 186 8.3E-25 T 22-04-2016 TOLA_RS03590 1c662793bc459be58586a1c7af03d0b4 186 Gene3D G3DSA:3.90.190.10 24 180 2.4E-38 T 22-04-2016 IPR029021 Protein-tyrosine phosphatase-like TOLA_RS03590 1c662793bc459be58586a1c7af03d0b4 186 PANTHER PTHR23339 12 186 8.3E-25 T 22-04-2016 TOLA_RS03590 1c662793bc459be58586a1c7af03d0b4 186 SMART SM00404 87 185 4.0E-4 T 22-04-2016 IPR003595 Protein-tyrosine phosphatase, catalytic TOLA_RS13690 448a6935904eb27753855b60c337039d 205 SUPERFAMILY SSF109604 11 200 1.75E-45 T 22-04-2016 TOLA_RS13690 448a6935904eb27753855b60c337039d 205 SMART SM00471 33 158 8.1E-6 T 22-04-2016 IPR003607 HD/PDEase domain TOLA_RS13690 448a6935904eb27753855b60c337039d 205 ProDom PD353566 UPF0207 HYDROLASE HD PHOSPHOHYDROLASE METAL-DEPENDENT SUBDOMAIN YFBR PHOSPHOHYDROLASE NUCLEOTIDE-BINDING NUCLEOSIDE 87 191 6.0E-30 T 22-04-2016 TOLA_RS13690 448a6935904eb27753855b60c337039d 205 PANTHER PTHR11845 1 197 1.1E-36 T 22-04-2016 TOLA_RS13690 448a6935904eb27753855b60c337039d 205 Hamap MF_01100 5'-deoxynucleotidase YfbR [yfbR]. 10 202 41.215 T 22-04-2016 IPR022971 5'-deoxynucleotidase YfbR KEGG: 00240+3.1.3.89 TOLA_RS13690 448a6935904eb27753855b60c337039d 205 Gene3D G3DSA:1.10.3210.10 10 201 4.3E-49 T 22-04-2016 IPR006674 HD domain TOLA_RS13690 448a6935904eb27753855b60c337039d 205 Pfam PF13023 HD domain 18 163 1.8E-20 T 22-04-2016 IPR006674 HD domain TOLA_RS09600 3541d2bbc3b75c83b4fd1d1467050153 273 PANTHER PTHR31756 1 272 2.1E-104 T 22-04-2016 TOLA_RS09600 3541d2bbc3b75c83b4fd1d1467050153 273 PANTHER PTHR31756:SF3 1 272 2.1E-104 T 22-04-2016 TOLA_RS09600 3541d2bbc3b75c83b4fd1d1467050153 273 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 2 273 66.398 T 22-04-2016 IPR026530 Phosphoenolpyruvate synthase regulatory protein TOLA_RS09600 3541d2bbc3b75c83b4fd1d1467050153 273 Pfam PF03618 Kinase/pyrophosphorylase 5 264 1.7E-70 T 22-04-2016 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 Gene3D G3DSA:1.10.1040.10 183 329 1.6E-56 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 PIRSF PIRSF000114 2 334 1.3E-96 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 SUPERFAMILY SSF48179 183 334 2.38E-55 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 59 86 1.9E-40 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 9 26 1.9E-40 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 1.9E-40 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 135 155 1.9E-40 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 1.9E-40 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 1.9E-40 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 PANTHER PTHR11728 8 334 3.5E-132 T 22-04-2016 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 SUPERFAMILY SSF51735 7 181 5.7E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 Gene3D G3DSA:3.40.50.720 8 181 5.4E-52 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 322 6.7E-51 T 22-04-2016 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 8 162 5.5E-48 T 22-04-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 TOLA_RS02635 ffe4914e74d0d4872938c68d38dbfc28 334 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 5 325 36.865 T 22-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 TOLA_RS05070 dc69fe79d6838d77177377fa61a4d19b 101 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 11 100 1.9E-9 T 22-04-2016 IPR008407 Branched-chain amino acid transport, AzlD TOLA_RS02215 7f06c13a49a84b001acf8419a6e25a5e 192 SMART SM00749 129 192 2.5E-8 T 22-04-2016 IPR014004 Transport-associated and nodulation domain, bacteria TOLA_RS02215 7f06c13a49a84b001acf8419a6e25a5e 192 SMART SM00749 51 114 150.0 T 22-04-2016 IPR014004 Transport-associated and nodulation domain, bacteria TOLA_RS02215 7f06c13a49a84b001acf8419a6e25a5e 192 PANTHER PTHR34606 2 191 3.1E-62 T 22-04-2016 TOLA_RS02215 7f06c13a49a84b001acf8419a6e25a5e 192 Pfam PF04972 BON domain 124 189 5.0E-17 T 22-04-2016 IPR007055 BON domain TOLA_RS02215 7f06c13a49a84b001acf8419a6e25a5e 192 Pfam PF04972 BON domain 46 114 1.1E-8 T 22-04-2016 IPR007055 BON domain TOLA_RS02215 7f06c13a49a84b001acf8419a6e25a5e 192 PANTHER PTHR34606:SF4 2 191 3.1E-62 T 22-04-2016 TOLA_RS04670 c55f5b29771ec5e56a7da8e469426ce1 256 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 2 256 40.186 T 22-04-2016 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386|UniPathway: UPA00619 TOLA_RS04670 c55f5b29771ec5e56a7da8e469426ce1 256 SMART SM00849 12 168 5.7E-33 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS04670 c55f5b29771ec5e56a7da8e469426ce1 256 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 5 255 6.9E-90 T 22-04-2016 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386|UniPathway: UPA00619 TOLA_RS04670 c55f5b29771ec5e56a7da8e469426ce1 256 PANTHER PTHR11935 1 255 8.7E-83 T 22-04-2016 TOLA_RS04670 c55f5b29771ec5e56a7da8e469426ce1 256 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 169 255 1.1E-20 T 22-04-2016 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386|UniPathway: UPA00619 TOLA_RS04670 c55f5b29771ec5e56a7da8e469426ce1 256 Gene3D G3DSA:3.60.15.10 4 255 3.5E-80 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS04670 c55f5b29771ec5e56a7da8e469426ce1 256 PANTHER PTHR11935:SF7 1 255 8.7E-83 T 22-04-2016 TOLA_RS04670 c55f5b29771ec5e56a7da8e469426ce1 256 SUPERFAMILY SSF56281 2 254 1.44E-65 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS04670 c55f5b29771ec5e56a7da8e469426ce1 256 Pfam PF00753 Metallo-beta-lactamase superfamily 14 168 4.8E-20 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS04670 c55f5b29771ec5e56a7da8e469426ce1 256 PIRSF PIRSF005457 1 256 1.5E-82 T 22-04-2016 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386|UniPathway: UPA00619 TOLA_RS01225 a86f27f9ab24bac6ba39da47b1744abb 190 Hamap MF_00984 Single-stranded DNA-binding protein. 5 112 38.891 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 TOLA_RS01225 a86f27f9ab24bac6ba39da47b1744abb 190 Pfam PF00436 Single-strand binding protein family 5 108 5.6E-45 T 22-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 TOLA_RS01225 a86f27f9ab24bac6ba39da47b1744abb 190 PANTHER PTHR10302 1 190 1.6E-61 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 TOLA_RS01225 a86f27f9ab24bac6ba39da47b1744abb 190 SUPERFAMILY SSF50249 3 190 1.13E-60 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS01225 a86f27f9ab24bac6ba39da47b1744abb 190 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 190 6.7E-64 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 TOLA_RS01225 a86f27f9ab24bac6ba39da47b1744abb 190 Gene3D G3DSA:2.40.50.140 1 122 6.7E-59 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS01225 a86f27f9ab24bac6ba39da47b1744abb 190 Gene3D G3DSA:2.40.50.140 170 190 6.7E-59 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS00080 bea03200ba14ddbda1f5aaf66a9e2822 361 SMART SM00382 27 214 3.1E-20 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS00080 bea03200ba14ddbda1f5aaf66a9e2822 361 Gene3D G3DSA:3.40.50.300 3 241 3.6E-82 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00080 bea03200ba14ddbda1f5aaf66a9e2822 361 SUPERFAMILY SSF50331 240 349 3.85E-8 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS00080 bea03200ba14ddbda1f5aaf66a9e2822 361 Pfam PF00005 ABC transporter 18 164 1.9E-37 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS00080 bea03200ba14ddbda1f5aaf66a9e2822 361 PANTHER PTHR24220:SF123 329 344 1.1E-136 T 22-04-2016 TOLA_RS00080 bea03200ba14ddbda1f5aaf66a9e2822 361 PANTHER PTHR24220:SF123 4 279 1.1E-136 T 22-04-2016 TOLA_RS00080 bea03200ba14ddbda1f5aaf66a9e2822 361 SUPERFAMILY SSF52540 3 246 5.86E-88 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00080 bea03200ba14ddbda1f5aaf66a9e2822 361 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS00080 bea03200ba14ddbda1f5aaf66a9e2822 361 PANTHER PTHR24220 329 344 1.1E-136 T 22-04-2016 TOLA_RS00080 bea03200ba14ddbda1f5aaf66a9e2822 361 PANTHER PTHR24220 4 279 1.1E-136 T 22-04-2016 TOLA_RS00080 bea03200ba14ddbda1f5aaf66a9e2822 361 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 241 3.0E-120 T 22-04-2016 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 TOLA_RS00080 bea03200ba14ddbda1f5aaf66a9e2822 361 Pfam PF12857 TOBE-like domain 288 347 4.4E-13 T 22-04-2016 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 TOLA_RS02710 cb782ce3a3adac8484dd09cad76f2133 430 Gene3D G3DSA:3.40.1190.10 89 291 2.2E-67 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02710 cb782ce3a3adac8484dd09cad76f2133 430 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 3 428 7.4E-130 T 22-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS02710 cb782ce3a3adac8484dd09cad76f2133 430 SUPERFAMILY SSF53623 90 289 1.83E-56 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02710 cb782ce3a3adac8484dd09cad76f2133 430 SUPERFAMILY SSF53244 291 430 5.95E-44 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS02710 cb782ce3a3adac8484dd09cad76f2133 430 Gene3D G3DSA:3.90.190.20 293 427 1.4E-42 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS02710 cb782ce3a3adac8484dd09cad76f2133 430 Gene3D G3DSA:3.40.50.720 2 87 6.1E-23 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS02710 cb782ce3a3adac8484dd09cad76f2133 430 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 2 430 34.937 T 22-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS02710 cb782ce3a3adac8484dd09cad76f2133 430 PANTHER PTHR23135:SF2 1 430 1.7E-160 T 22-04-2016 TOLA_RS02710 cb782ce3a3adac8484dd09cad76f2133 430 Pfam PF08245 Mur ligase middle domain 105 272 7.8E-30 T 22-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 TOLA_RS02710 cb782ce3a3adac8484dd09cad76f2133 430 Pfam PF02875 Mur ligase family, glutamate ligase domain 293 364 2.9E-9 T 22-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 TOLA_RS02710 cb782ce3a3adac8484dd09cad76f2133 430 SUPERFAMILY SSF51984 2 89 2.88E-19 T 22-04-2016 TOLA_RS02710 cb782ce3a3adac8484dd09cad76f2133 430 PANTHER PTHR23135 1 430 1.7E-160 T 22-04-2016 TOLA_RS04045 4acda42e67e7105fc34538ca8f36b49d 200 SUPERFAMILY SSF52833 1 84 7.78E-19 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS04045 4acda42e67e7105fc34538ca8f36b49d 200 Gene3D G3DSA:3.40.30.10 1 87 2.4E-28 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS04045 4acda42e67e7105fc34538ca8f36b49d 200 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 74 3.5E-10 T 22-04-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TOLA_RS04045 4acda42e67e7105fc34538ca8f36b49d 200 SUPERFAMILY SSF47616 81 197 6.13E-26 T 22-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like TOLA_RS04045 4acda42e67e7105fc34538ca8f36b49d 200 Gene3D G3DSA:1.20.1050.10 88 187 3.2E-32 T 22-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like TOLA_RS04045 4acda42e67e7105fc34538ca8f36b49d 200 PANTHER PTHR11260:SF154 1 195 1.6E-77 T 22-04-2016 TOLA_RS04045 4acda42e67e7105fc34538ca8f36b49d 200 PANTHER PTHR11260 1 195 1.6E-77 T 22-04-2016 TOLA_RS04045 4acda42e67e7105fc34538ca8f36b49d 200 Pfam PF00043 Glutathione S-transferase, C-terminal domain 103 188 3.3E-10 T 22-04-2016 IPR004046 Glutathione S-transferase, C-terminal TOLA_RS06160 70d7465f3ca13262f2e2517160958302 93 Gene3D G3DSA:1.10.10.10 33 82 4.5E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06160 70d7465f3ca13262f2e2517160958302 93 Hamap MF_00674 UPF0251 protein . 2 93 22.572 T 22-04-2016 IPR002852 Uncharacterised protein family UPF0251 TOLA_RS06160 70d7465f3ca13262f2e2517160958302 93 PANTHER PTHR37478 1 89 1.6E-26 T 22-04-2016 TOLA_RS06160 70d7465f3ca13262f2e2517160958302 93 SUPERFAMILY SSF88659 33 81 3.27E-5 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS06160 70d7465f3ca13262f2e2517160958302 93 PANTHER PTHR37478:SF1 1 89 1.6E-26 T 22-04-2016 TOLA_RS06160 70d7465f3ca13262f2e2517160958302 93 Pfam PF02001 Protein of unknown function DUF134 2 90 1.5E-22 T 22-04-2016 IPR002852 Uncharacterised protein family UPF0251 TOLA_RS00700 581ef42648a6135450ed5ff6e1a272e7 239 Gene3D G3DSA:3.90.1200.10 177 237 2.7E-7 T 22-04-2016 TOLA_RS00700 581ef42648a6135450ed5ff6e1a272e7 239 SUPERFAMILY SSF56112 47 211 1.2E-17 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS00700 581ef42648a6135450ed5ff6e1a272e7 239 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 32 235 2.4E-61 T 22-04-2016 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 TOLA_RS00700 581ef42648a6135450ed5ff6e1a272e7 239 Gene3D G3DSA:1.10.510.10 105 176 8.1E-9 T 22-04-2016 TOLA_RS00700 581ef42648a6135450ed5ff6e1a272e7 239 Hamap MF_00521 3-deoxy-D-manno-octulosonic acid kinase [kdkA]. 1 237 34.621 T 22-04-2016 IPR022826 3-deoxy-D-manno-octulosonic acid kinase GO:0016773 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.1.166|MetaCyc: PWY-7675|MetaCyc: PWY-7676|UniPathway: UPA00958 TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 Pfam PF00027 Cyclic nucleotide-binding domain 51 132 3.1E-16 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 SMART SM00419 187 235 1.3E-15 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 SUPERFAMILY SSF51206 23 162 7.99E-31 T 22-04-2016 IPR018490 Cyclic nucleotide-binding-like TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 ProSitePatterns PS00042 Crp-type HTH domain signature. 195 218 - T 22-04-2016 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 PANTHER PTHR24567 5 249 9.4E-117 T 22-04-2016 TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 PANTHER PTHR24567:SF28 5 249 9.4E-117 T 22-04-2016 TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 SMART SM00100 30 151 8.6E-18 T 22-04-2016 IPR000595 Cyclic nucleotide-binding domain TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 Gene3D G3DSA:1.10.10.10 170 244 2.2E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 Pfam PF13545 Crp-like helix-turn-helix domain 168 242 1.9E-17 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 Gene3D G3DSA:2.60.120.10 18 169 2.2E-40 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 SUPERFAMILY SSF46785 165 244 8.91E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 193 209 5.4E-12 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TOLA_RS11180 650a1703a3940aab2e2b2d8fdecfe30a 252 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 209 224 5.4E-12 T 22-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 22-04-2016 IPR020583 Inositol monophosphatase, metal-binding site TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 Gene3D G3DSA:3.40.190.80 152 260 2.9E-39 T 22-04-2016 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 PANTHER PTHR20854 1 260 4.0E-103 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 198 210 2.0E-30 T 22-04-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 156 182 2.0E-30 T 22-04-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 2.0E-30 T 22-04-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 2.0E-30 T 22-04-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 8.5E-61 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 8.5E-61 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 8.5E-61 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 8.5E-61 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 8.5E-61 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 8.5E-61 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 PANTHER PTHR20854:SF4 1 260 4.0E-103 T 22-04-2016 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 Pfam PF00459 Inositol monophosphatase family 2 261 1.1E-72 T 22-04-2016 IPR000760 Inositol monophosphatase GO:0046854 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 SUPERFAMILY SSF56655 1 261 1.44E-89 T 22-04-2016 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 Gene3D G3DSA:3.30.540.10 2 151 1.5E-54 T 22-04-2016 TOLA_RS10550 059d967a31789ae91e2a8657b4431fd2 267 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 211 225 - T 22-04-2016 IPR020550 Inositol monophosphatase, conserved site GO:0046854 TOLA_RS12075 4de064bc81ebd43fd8d784c30421734c 239 PANTHER PTHR34390:SF2 1 237 1.5E-97 T 22-04-2016 TOLA_RS12075 4de064bc81ebd43fd8d784c30421734c 239 Pfam PF06738 Putative threonine/serine exporter 1 231 4.9E-65 T 22-04-2016 IPR010619 Putative threonine/serine exporter TOLA_RS12075 4de064bc81ebd43fd8d784c30421734c 239 PANTHER PTHR34390 1 237 1.5E-97 T 22-04-2016 TOLA_RS10495 3e0b539e02a1d4de4ec80fff83e47c61 164 Pfam PF14437 MafB19-like deaminase 8 152 1.5E-31 T 22-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 TOLA_RS10495 3e0b539e02a1d4de4ec80fff83e47c61 164 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 11 152 48.061 T 22-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 TOLA_RS10495 3e0b539e02a1d4de4ec80fff83e47c61 164 SUPERFAMILY SSF53927 4 156 5.86E-57 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 TOLA_RS10495 3e0b539e02a1d4de4ec80fff83e47c61 164 Gene3D G3DSA:3.40.140.10 3 150 8.2E-59 T 22-04-2016 TOLA_RS10495 3e0b539e02a1d4de4ec80fff83e47c61 164 PANTHER PTHR11079 3 155 1.3E-47 T 22-04-2016 TOLA_RS10495 3e0b539e02a1d4de4ec80fff83e47c61 164 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 93 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TOLA_RS10560 cd7845ce3a97d2b5bff3c4b74095128e 186 SUPERFAMILY SSF51182 61 183 4.75E-21 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS10560 cd7845ce3a97d2b5bff3c4b74095128e 186 Pfam PF07883 Cupin domain 111 177 1.8E-11 T 22-04-2016 IPR013096 Cupin 2, conserved barrel TOLA_RS10560 cd7845ce3a97d2b5bff3c4b74095128e 186 Gene3D G3DSA:1.10.260.40 3 73 2.9E-22 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS10560 cd7845ce3a97d2b5bff3c4b74095128e 186 SUPERFAMILY SSF47413 3 69 2.12E-16 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS10560 cd7845ce3a97d2b5bff3c4b74095128e 186 Gene3D G3DSA:2.60.120.10 95 184 7.4E-29 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS10560 cd7845ce3a97d2b5bff3c4b74095128e 186 PANTHER PTHR10245 1 183 2.5E-48 T 22-04-2016 TOLA_RS10560 cd7845ce3a97d2b5bff3c4b74095128e 186 Pfam PF01381 Helix-turn-helix 12 64 6.7E-14 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS10560 cd7845ce3a97d2b5bff3c4b74095128e 186 PANTHER PTHR10245:SF9 1 183 2.5E-48 T 22-04-2016 TOLA_RS10560 cd7845ce3a97d2b5bff3c4b74095128e 186 SMART SM00530 11 66 6.3E-13 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS14140 d585660a6e92d14f53b5d15b9112ac3e 161 PANTHER PTHR37952:SF2 1 148 1.4E-56 T 22-04-2016 TOLA_RS14140 d585660a6e92d14f53b5d15b9112ac3e 161 PIRSF PIRSF003174 1 160 1.0E-54 T 22-04-2016 IPR010292 Uncharacterised protein family CreA TOLA_RS14140 d585660a6e92d14f53b5d15b9112ac3e 161 PANTHER PTHR37952 1 148 1.4E-56 T 22-04-2016 TOLA_RS14140 d585660a6e92d14f53b5d15b9112ac3e 161 Pfam PF05981 CreA protein 24 149 5.4E-50 T 22-04-2016 IPR010292 Uncharacterised protein family CreA TOLA_RS06815 7be8f29583c279c68e4ffa7da91ce3f9 421 Pfam PF13416 Bacterial extracellular solute-binding protein 47 351 2.1E-30 T 22-04-2016 TOLA_RS06815 7be8f29583c279c68e4ffa7da91ce3f9 421 SUPERFAMILY SSF53850 27 408 1.81E-57 T 22-04-2016 TOLA_RS06815 7be8f29583c279c68e4ffa7da91ce3f9 421 Gene3D G3DSA:3.40.190.10 156 339 6.0E-34 T 22-04-2016 TOLA_RS06815 7be8f29583c279c68e4ffa7da91ce3f9 421 Gene3D G3DSA:3.40.190.10 31 155 1.2E-7 T 22-04-2016 TOLA_RS06815 7be8f29583c279c68e4ffa7da91ce3f9 421 PANTHER PTHR30061 1 415 1.9E-45 T 22-04-2016 TOLA_RS10500 2a7947e9692bd1164e02e6e3f584bf43 324 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 5 310 7.6E-85 T 22-04-2016 IPR011862 Phosphate binding protein GO:0006810 TOLA_RS10500 2a7947e9692bd1164e02e6e3f584bf43 324 PANTHER PTHR30570:SF5 40 322 1.8E-164 T 22-04-2016 TOLA_RS10500 2a7947e9692bd1164e02e6e3f584bf43 324 Pfam PF12849 PBP superfamily domain 40 295 1.0E-31 T 22-04-2016 IPR024370 PBP domain TOLA_RS10500 2a7947e9692bd1164e02e6e3f584bf43 324 SUPERFAMILY SSF53850 38 323 8.54E-72 T 22-04-2016 TOLA_RS10500 2a7947e9692bd1164e02e6e3f584bf43 324 Gene3D G3DSA:3.40.190.10 124 267 4.4E-35 T 22-04-2016 TOLA_RS10500 2a7947e9692bd1164e02e6e3f584bf43 324 Gene3D G3DSA:3.40.190.10 44 121 3.5E-11 T 22-04-2016 TOLA_RS10500 2a7947e9692bd1164e02e6e3f584bf43 324 Gene3D G3DSA:3.40.190.10 268 319 3.5E-11 T 22-04-2016 TOLA_RS10500 2a7947e9692bd1164e02e6e3f584bf43 324 PANTHER PTHR30570 40 322 1.8E-164 T 22-04-2016 TOLA_RS07650 6af87488077bc7b26ef5c1eb129a509a 328 Pfam PF00248 Aldo/keto reductase family 16 305 6.9E-70 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS07650 6af87488077bc7b26ef5c1eb129a509a 328 SUPERFAMILY SSF51430 1 314 3.14E-93 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS07650 6af87488077bc7b26ef5c1eb129a509a 328 PANTHER PTHR11732 1 324 2.2E-169 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta TOLA_RS07650 6af87488077bc7b26ef5c1eb129a509a 328 Gene3D G3DSA:3.20.20.100 1 322 8.8E-105 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS07650 6af87488077bc7b26ef5c1eb129a509a 328 PRINTS PR00069 Aldo-keto reductase signature 239 263 5.8E-6 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS07650 6af87488077bc7b26ef5c1eb129a509a 328 PRINTS PR00069 Aldo-keto reductase signature 106 124 5.8E-6 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS07650 6af87488077bc7b26ef5c1eb129a509a 328 PRINTS PR00069 Aldo-keto reductase signature 43 67 5.8E-6 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS07650 6af87488077bc7b26ef5c1eb129a509a 328 PANTHER PTHR11732:SF215 1 324 2.2E-169 T 22-04-2016 TOLA_RS10075 631e634039a4b58515be4ef3156af644 259 Gene3D G3DSA:3.40.190.10 16 140 2.8E-35 T 22-04-2016 TOLA_RS10075 631e634039a4b58515be4ef3156af644 259 SUPERFAMILY SSF53850 6 253 8.62E-50 T 22-04-2016 TOLA_RS10075 631e634039a4b58515be4ef3156af644 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 252 4.3E-43 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS10075 631e634039a4b58515be4ef3156af644 259 SMART SM00062 34 254 1.4E-32 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS10075 631e634039a4b58515be4ef3156af644 259 PANTHER PTHR18966:SF191 20 250 7.3E-40 T 22-04-2016 TOLA_RS10075 631e634039a4b58515be4ef3156af644 259 Gene3D G3DSA:3.40.190.10 141 203 3.9E-9 T 22-04-2016 TOLA_RS10075 631e634039a4b58515be4ef3156af644 259 PANTHER PTHR18966 20 250 7.3E-40 T 22-04-2016 TOLA_RS15585 532dcc1b0493c595d37ae354340c2f96 355 SUPERFAMILY SSF47413 1 63 6.97E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS15585 532dcc1b0493c595d37ae354340c2f96 355 PANTHER PTHR10245 1 273 1.3E-22 T 22-04-2016 TOLA_RS15585 532dcc1b0493c595d37ae354340c2f96 355 Pfam PF06114 Domain of unknown function (DUF955) 155 270 1.2E-15 T 22-04-2016 IPR010359 HTH domain, IrrE-type TOLA_RS15585 532dcc1b0493c595d37ae354340c2f96 355 PANTHER PTHR10245:SF22 1 273 1.3E-22 T 22-04-2016 TOLA_RS15585 532dcc1b0493c595d37ae354340c2f96 355 Pfam PF01381 Helix-turn-helix 8 59 1.2E-9 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS15585 532dcc1b0493c595d37ae354340c2f96 355 SMART SM00530 5 60 1.5E-11 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS15585 532dcc1b0493c595d37ae354340c2f96 355 Gene3D G3DSA:1.10.260.40 1 72 9.8E-16 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS01805 f03d25f94c6e6a9e9200970fdc8bd00e 720 Pfam PF05954 Phage late control gene D protein (GPD) 30 322 2.2E-67 T 22-04-2016 TOLA_RS01805 f03d25f94c6e6a9e9200970fdc8bd00e 720 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 24 497 3.9E-106 T 22-04-2016 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein TOLA_RS01805 f03d25f94c6e6a9e9200970fdc8bd00e 720 SUPERFAMILY SSF69279 11 186 5.44E-48 T 22-04-2016 TOLA_RS01805 f03d25f94c6e6a9e9200970fdc8bd00e 720 SUPERFAMILY SSF69279 192 356 3.23E-26 T 22-04-2016 TOLA_RS01805 f03d25f94c6e6a9e9200970fdc8bd00e 720 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 13 515 9.1E-164 T 22-04-2016 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset TOLA_RS01805 f03d25f94c6e6a9e9200970fdc8bd00e 720 Gene3D G3DSA:2.40.50.230 364 444 5.6E-37 T 22-04-2016 IPR006531 Gp5 N-terminal TOLA_RS01805 f03d25f94c6e6a9e9200970fdc8bd00e 720 PANTHER PTHR32305 1 618 5.0E-122 T 22-04-2016 TOLA_RS01805 f03d25f94c6e6a9e9200970fdc8bd00e 720 SUPERFAMILY SSF69349 435 616 2.9E-37 T 22-04-2016 TOLA_RS01805 f03d25f94c6e6a9e9200970fdc8bd00e 720 SUPERFAMILY SSF69255 357 445 1.91E-32 T 22-04-2016 TOLA_RS01805 f03d25f94c6e6a9e9200970fdc8bd00e 720 PANTHER PTHR32305:SF11 1 618 5.0E-122 T 22-04-2016 TOLA_RS01805 f03d25f94c6e6a9e9200970fdc8bd00e 720 Gene3D G3DSA:3.55.50.10 98 191 1.2E-27 T 22-04-2016 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 SUPERFAMILY SSF52540 6 288 2.16E-105 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 Gene3D G3DSA:3.40.50.300 6 293 7.8E-103 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 6.3E-32 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 Gene3D G3DSA:3.30.230.10 489 604 3.7E-47 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 Hamap MF_00054_B Elongation factor G [fusA]. 6 697 110.519 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 Gene3D G3DSA:3.30.70.870 411 485 8.8E-39 T 22-04-2016 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 PANTHER PTHR23115 3 184 0.0 T 22-04-2016 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.4E-16 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 PRINTS PR00315 GTP-binding elongation factor signature 85 95 1.4E-16 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.4E-16 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 PRINTS PR00315 GTP-binding elongation factor signature 137 146 1.4E-16 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 PRINTS PR00315 GTP-binding elongation factor signature 101 112 1.4E-16 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 SUPERFAMILY SSF54980 609 696 4.41E-30 T 22-04-2016 IPR009022 Elongation factor G, III-V domain TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 Pfam PF00679 Elongation factor G C-terminus 606 691 1.0E-30 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 Pfam PF03144 Elongation factor Tu domain 2 329 396 1.2E-15 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 SUPERFAMILY SSF54980 409 486 5.04E-25 T 22-04-2016 IPR009022 Elongation factor G, III-V domain TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 2.8E-67 T 22-04-2016 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 Pfam PF03764 Elongation factor G, domain IV 484 604 1.3E-46 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 Pfam PF14492 Elongation Factor G, domain II 409 483 8.6E-34 T 22-04-2016 IPR009022 Elongation factor G, III-V domain TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 SMART SM00838 606 693 1.5E-58 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 Gene3D G3DSA:3.30.70.240 605 691 6.6E-33 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 SMART SM00889 485 604 3.2E-70 T 22-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 PANTHER PTHR23115 261 289 0.0 T 22-04-2016 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 PANTHER PTHR23115 308 697 0.0 T 22-04-2016 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 SUPERFAMILY SSF54211 484 605 7.33E-42 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 PANTHER PTHR23115:SF66 261 289 0.0 T 22-04-2016 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 PANTHER PTHR23115:SF66 3 184 0.0 T 22-04-2016 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 PANTHER PTHR23115:SF66 308 697 0.0 T 22-04-2016 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 698 0.0 T 22-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 Gene3D G3DSA:2.40.30.10 311 410 3.2E-36 T 22-04-2016 TOLA_RS14210 2085cb9c899c69940c9279d4998306d2 700 SUPERFAMILY SSF50447 271 409 2.04E-34 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain TOLA_RS13020 b51cd3eb807e59a3f5f4ad70b39c2ab3 332 Gene3D G3DSA:3.40.190.10 125 279 1.1E-59 T 22-04-2016 TOLA_RS13020 b51cd3eb807e59a3f5f4ad70b39c2ab3 332 PANTHER PTHR30006:SF4 1 332 2.8E-165 T 22-04-2016 TOLA_RS13020 b51cd3eb807e59a3f5f4ad70b39c2ab3 332 PANTHER PTHR30006 1 332 2.8E-165 T 22-04-2016 TOLA_RS13020 b51cd3eb807e59a3f5f4ad70b39c2ab3 332 PIRSF PIRSF002825 4 332 1.9E-92 T 22-04-2016 IPR026045 Ferric binding protein TOLA_RS13020 b51cd3eb807e59a3f5f4ad70b39c2ab3 332 SUPERFAMILY SSF53850 19 329 3.43E-77 T 22-04-2016 TOLA_RS13020 b51cd3eb807e59a3f5f4ad70b39c2ab3 332 Gene3D G3DSA:3.40.190.10 18 124 6.1E-22 T 22-04-2016 TOLA_RS13020 b51cd3eb807e59a3f5f4ad70b39c2ab3 332 Pfam PF13343 Bacterial extracellular solute-binding protein 68 292 8.5E-22 T 22-04-2016 TOLA_RS08270 3540c7c7d6577e7406df60a8cdd74d36 260 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 16 257 3.9E-117 T 22-04-2016 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD TOLA_RS08270 3540c7c7d6577e7406df60a8cdd74d36 260 Pfam PF00005 ABC transporter 32 187 1.9E-26 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS08270 3540c7c7d6577e7406df60a8cdd74d36 260 SUPERFAMILY SSF52540 16 256 1.01E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08270 3540c7c7d6577e7406df60a8cdd74d36 260 PANTHER PTHR24220:SF366 18 257 2.9E-129 T 22-04-2016 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD TOLA_RS08270 3540c7c7d6577e7406df60a8cdd74d36 260 PANTHER PTHR24220 18 257 2.9E-129 T 22-04-2016 TOLA_RS08270 3540c7c7d6577e7406df60a8cdd74d36 260 Gene3D G3DSA:3.40.50.300 15 256 3.3E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08270 3540c7c7d6577e7406df60a8cdd74d36 260 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 235 256 2.6E-9 T 22-04-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TOLA_RS01180 b0801b2b5f61ba25d05cbd2a71cec8c7 389 PANTHER PTHR18964:SF123 54 337 2.5E-27 T 22-04-2016 TOLA_RS01180 b0801b2b5f61ba25d05cbd2a71cec8c7 389 Pfam PF00480 ROK family 125 353 8.3E-30 T 22-04-2016 IPR000600 ROK family TOLA_RS01180 b0801b2b5f61ba25d05cbd2a71cec8c7 389 Gene3D G3DSA:3.30.420.40 219 353 3.5E-31 T 22-04-2016 TOLA_RS01180 b0801b2b5f61ba25d05cbd2a71cec8c7 389 SUPERFAMILY SSF46785 8 60 1.1E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01180 b0801b2b5f61ba25d05cbd2a71cec8c7 389 SUPERFAMILY SSF53067 206 357 3.24E-30 T 22-04-2016 TOLA_RS01180 b0801b2b5f61ba25d05cbd2a71cec8c7 389 Gene3D G3DSA:1.10.10.10 6 73 9.1E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01180 b0801b2b5f61ba25d05cbd2a71cec8c7 389 PANTHER PTHR18964 54 337 2.5E-27 T 22-04-2016 TOLA_RS01180 b0801b2b5f61ba25d05cbd2a71cec8c7 389 Gene3D G3DSA:3.30.420.40 76 218 4.3E-12 T 22-04-2016 TOLA_RS03940 a9afbe60736770eed28563a6796777b4 765 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 23 636 2.9E-262 T 22-04-2016 IPR022946 Uncharacterised protein family UPF0313 TOLA_RS03940 a9afbe60736770eed28563a6796777b4 765 Gene3D G3DSA:3.80.30.20 366 615 1.6E-47 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe TOLA_RS03940 a9afbe60736770eed28563a6796777b4 765 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 22 704 47.995 T 22-04-2016 IPR022946 Uncharacterised protein family UPF0313 TOLA_RS03940 a9afbe60736770eed28563a6796777b4 765 SMART SM00729 368 618 6.7E-5 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TOLA_RS03940 a9afbe60736770eed28563a6796777b4 765 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 372 392 - T 22-04-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 TOLA_RS03940 a9afbe60736770eed28563a6796777b4 765 Pfam PF04055 Radical SAM superfamily 372 577 2.2E-21 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS03940 a9afbe60736770eed28563a6796777b4 765 PANTHER PTHR32331 2 719 0.0 T 22-04-2016 TOLA_RS03940 a9afbe60736770eed28563a6796777b4 765 Pfam PF08497 Radical SAM N-terminal 23 371 4.6E-144 T 22-04-2016 IPR013704 Uncharacterised protein family UPF0313, N-terminal TOLA_RS03940 a9afbe60736770eed28563a6796777b4 765 Pfam PF11842 Domain of unknown function (DUF3362) 586 723 3.0E-37 T 22-04-2016 IPR024560 Uncharacterised protein family UPF0313, C-terminal TOLA_RS03940 a9afbe60736770eed28563a6796777b4 765 SUPERFAMILY SSF102114 465 634 2.49E-11 T 22-04-2016 TOLA_RS03940 a9afbe60736770eed28563a6796777b4 765 SUPERFAMILY SSF102114 371 435 2.49E-11 T 22-04-2016 TOLA_RS03940 a9afbe60736770eed28563a6796777b4 765 PANTHER PTHR32331:SF3 2 719 0.0 T 22-04-2016 TOLA_RS14885 a9d4c2dc15c514bba5739a6118272d96 230 PANTHER PTHR18901 9 216 9.1E-59 T 22-04-2016 TOLA_RS14885 a9d4c2dc15c514bba5739a6118272d96 230 Gene3D G3DSA:3.40.50.1000 98 222 4.5E-44 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS14885 a9d4c2dc15c514bba5739a6118272d96 230 Gene3D G3DSA:3.40.50.1000 5 24 4.5E-44 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS14885 a9d4c2dc15c514bba5739a6118272d96 230 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 81 191 6.9E-14 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS14885 a9d4c2dc15c514bba5739a6118272d96 230 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 98 188 9.6E-6 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS14885 a9d4c2dc15c514bba5739a6118272d96 230 ProSitePatterns PS01228 Hypothetical cof family signature 1. 12 23 - T 22-04-2016 IPR000150 Cof protein GO:0016787 TOLA_RS14885 a9d4c2dc15c514bba5739a6118272d96 230 SUPERFAMILY SSF56784 10 221 1.12E-49 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS14885 a9d4c2dc15c514bba5739a6118272d96 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 194 5.5E-34 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS05620 ced08a149e607bcfdfc23d9518a717e8 383 Gene3D G3DSA:3.90.1150.10 267 379 5.7E-33 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS05620 ced08a149e607bcfdfc23d9518a717e8 383 Pfam PF00155 Aminotransferase class I and II 39 375 2.4E-53 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TOLA_RS05620 ced08a149e607bcfdfc23d9518a717e8 383 SUPERFAMILY SSF53383 7 381 2.53E-102 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS05620 ced08a149e607bcfdfc23d9518a717e8 383 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 231 240 - T 22-04-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 TOLA_RS05620 ced08a149e607bcfdfc23d9518a717e8 383 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 1 380 46.449 T 22-04-2016 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147|UniPathway: UPA00078 TOLA_RS05620 ced08a149e607bcfdfc23d9518a717e8 383 Gene3D G3DSA:3.40.640.10 57 266 2.5E-79 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS05620 ced08a149e607bcfdfc23d9518a717e8 383 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 18 377 3.6E-136 T 22-04-2016 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147|UniPathway: UPA00078 TOLA_RS05620 ced08a149e607bcfdfc23d9518a717e8 383 PANTHER PTHR13693 5 383 3.5E-162 T 22-04-2016 TOLA_RS05620 ced08a149e607bcfdfc23d9518a717e8 383 PANTHER PTHR13693:SF53 5 383 3.5E-162 T 22-04-2016 TOLA_RS13520 7be2068485c98189204891d5df5a1869 501 SUPERFAMILY SSF109604 309 497 4.81E-43 T 22-04-2016 TOLA_RS13520 7be2068485c98189204891d5df5a1869 501 SUPERFAMILY SSF53067 9 128 1.72E-32 T 22-04-2016 TOLA_RS13520 7be2068485c98189204891d5df5a1869 501 SUPERFAMILY SSF53067 134 304 5.47E-39 T 22-04-2016 TOLA_RS13520 7be2068485c98189204891d5df5a1869 501 PIRSF PIRSF001267 1 499 4.1E-173 T 22-04-2016 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40|UniPathway: UPA00908 TOLA_RS13520 7be2068485c98189204891d5df5a1869 501 Gene3D G3DSA:3.30.420.150 130 305 1.1E-45 T 22-04-2016 TOLA_RS13520 7be2068485c98189204891d5df5a1869 501 Gene3D G3DSA:3.30.420.40 5 127 3.1E-39 T 22-04-2016 TOLA_RS13520 7be2068485c98189204891d5df5a1869 501 Pfam PF02541 Ppx/GppA phosphatase family 25 304 3.5E-81 T 22-04-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40|UniPathway: UPA00908 TOLA_RS13520 7be2068485c98189204891d5df5a1869 501 PANTHER PTHR30005 1 493 1.1E-211 T 22-04-2016 TOLA_RS13520 7be2068485c98189204891d5df5a1869 501 Hamap MF_01550 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [gppA]. 1 497 55.427 T 22-04-2016 IPR023709 Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase GO:0008894|GO:0015974 KEGG: 00230+3.6.1.40|UniPathway: UPA00908 TOLA_RS13520 7be2068485c98189204891d5df5a1869 501 PANTHER PTHR30005:SF2 1 493 1.1E-211 T 22-04-2016 TOLA_RS06395 a6a293db38ffaf161444af21760b7099 243 PANTHER PTHR30027:SF3 1 243 2.6E-97 T 22-04-2016 TOLA_RS06395 a6a293db38ffaf161444af21760b7099 243 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 4 242 2.8E-78 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS06395 a6a293db38ffaf161444af21760b7099 243 SUPERFAMILY SSF75217 75 242 1.79E-51 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases TOLA_RS06395 a6a293db38ffaf161444af21760b7099 243 Gene3D G3DSA:2.40.240.20 1 70 8.4E-26 T 22-04-2016 TOLA_RS06395 a6a293db38ffaf161444af21760b7099 243 SUPERFAMILY SSF88697 2 69 7.46E-17 T 22-04-2016 IPR015947 PUA-like domain TOLA_RS06395 a6a293db38ffaf161444af21760b7099 243 Pfam PF04452 RNA methyltransferase 18 236 6.8E-73 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS06395 a6a293db38ffaf161444af21760b7099 243 Gene3D G3DSA:3.40.1280.10 75 242 3.5E-58 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TOLA_RS06395 a6a293db38ffaf161444af21760b7099 243 PIRSF PIRSF015601 3 242 4.1E-52 T 22-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS06395 a6a293db38ffaf161444af21760b7099 243 PANTHER PTHR30027 1 243 2.6E-97 T 22-04-2016 TOLA_RS15060 15f7e5c766a0bf2f058f0aec3815e653 172 Gene3D G3DSA:2.60.450.10 24 158 9.3E-31 T 22-04-2016 TOLA_RS15060 15f7e5c766a0bf2f058f0aec3815e653 172 PANTHER PTHR36504 12 165 1.1E-40 T 22-04-2016 TOLA_RS15060 15f7e5c766a0bf2f058f0aec3815e653 172 Pfam PF03968 OstA-like protein 33 141 2.4E-25 T 22-04-2016 IPR005653 Organic solvent tolerance-like, N-terminal TOLA_RS15060 15f7e5c766a0bf2f058f0aec3815e653 172 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 22 161 1.3E-44 T 22-04-2016 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 TOLA_RS15060 15f7e5c766a0bf2f058f0aec3815e653 172 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 3 161 22.508 T 22-04-2016 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 TOLA_RS01310 6e66afad38f534fdf3656d0d9a0379c1 254 SMART SM01134 74 235 9.2E-68 T 22-04-2016 TOLA_RS01310 6e66afad38f534fdf3656d0d9a0379c1 254 Gene3D G3DSA:1.10.10.10 7 63 8.2E-10 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01310 6e66afad38f534fdf3656d0d9a0379c1 254 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 8.7E-15 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS01310 6e66afad38f534fdf3656d0d9a0379c1 254 PANTHER PTHR30363 1 253 2.9E-93 T 22-04-2016 TOLA_RS01310 6e66afad38f534fdf3656d0d9a0379c1 254 SMART SM00420 6 58 9.5E-13 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS01310 6e66afad38f534fdf3656d0d9a0379c1 254 Gene3D G3DSA:3.40.50.1360 77 225 5.9E-16 T 22-04-2016 TOLA_RS01310 6e66afad38f534fdf3656d0d9a0379c1 254 PANTHER PTHR30363:SF15 1 253 2.9E-93 T 22-04-2016 TOLA_RS01310 6e66afad38f534fdf3656d0d9a0379c1 254 SUPERFAMILY SSF100950 76 235 9.16E-34 T 22-04-2016 TOLA_RS01310 6e66afad38f534fdf3656d0d9a0379c1 254 SUPERFAMILY SSF46785 6 67 4.56E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01310 6e66afad38f534fdf3656d0d9a0379c1 254 Pfam PF00455 DeoR C terminal sensor domain 76 234 6.8E-49 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain TOLA_RS00070 8b4726d64bebfe02df4303a25791cd42 287 SUPERFAMILY SSF161098 29 272 2.34E-54 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00070 8b4726d64bebfe02df4303a25791cd42 287 PANTHER PTHR30406 10 286 1.3E-147 T 22-04-2016 TOLA_RS00070 8b4726d64bebfe02df4303a25791cd42 287 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 16 277 1.1E-92 T 22-04-2016 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 TOLA_RS00070 8b4726d64bebfe02df4303a25791cd42 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 278 3.3E-23 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00070 8b4726d64bebfe02df4303a25791cd42 287 Gene3D G3DSA:1.10.3720.10 27 276 1.3E-49 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00070 8b4726d64bebfe02df4303a25791cd42 287 PANTHER PTHR30406:SF6 10 286 1.3E-147 T 22-04-2016 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 TOLA_RS00070 8b4726d64bebfe02df4303a25791cd42 287 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 17 279 2.9E-121 T 22-04-2016 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 TOLA_RS06850 880816a4450626ace37c16f500ed1239 449 PIRSF PIRSF006060 1 441 2.0E-74 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 TOLA_RS06850 880816a4450626ace37c16f500ed1239 449 PANTHER PTHR11785:SF346 10 446 3.7E-199 T 22-04-2016 TOLA_RS06850 880816a4450626ace37c16f500ed1239 449 Pfam PF13520 Amino acid permease 22 401 1.5E-43 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 TOLA_RS06850 880816a4450626ace37c16f500ed1239 449 PANTHER PTHR11785 10 446 3.7E-199 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 TOLA_RS09965 1a81fb02b5f1a8dd5b846790fd5aea03 282 PANTHER PTHR30514:SF4 5 277 2.0E-44 T 22-04-2016 TOLA_RS09965 1a81fb02b5f1a8dd5b846790fd5aea03 282 SUPERFAMILY SSF53697 101 251 1.22E-11 T 22-04-2016 TOLA_RS09965 1a81fb02b5f1a8dd5b846790fd5aea03 282 Gene3D G3DSA:3.40.50.10490 66 249 2.4E-11 T 22-04-2016 TOLA_RS09965 1a81fb02b5f1a8dd5b846790fd5aea03 282 Pfam PF01380 SIS domain 128 229 3.1E-8 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 TOLA_RS09965 1a81fb02b5f1a8dd5b846790fd5aea03 282 PANTHER PTHR30514 5 277 2.0E-44 T 22-04-2016 TOLA_RS09965 1a81fb02b5f1a8dd5b846790fd5aea03 282 Gene3D G3DSA:1.10.10.10 5 65 1.6E-16 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09965 1a81fb02b5f1a8dd5b846790fd5aea03 282 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 75 2.3E-11 T 22-04-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 TOLA_RS09965 1a81fb02b5f1a8dd5b846790fd5aea03 282 SUPERFAMILY SSF46689 5 79 1.58E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS11305 e8fb56ae1f7a05fedc8183dbf8e3363f 389 PIRSF PIRSF001554 1 388 7.0E-152 T 22-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 TOLA_RS11305 e8fb56ae1f7a05fedc8183dbf8e3363f 389 Pfam PF08442 ATP-grasp domain 2 203 2.4E-80 T 22-04-2016 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS11305 e8fb56ae1f7a05fedc8183dbf8e3363f 389 Gene3D G3DSA:3.30.1490.20 22 93 2.9E-34 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS11305 e8fb56ae1f7a05fedc8183dbf8e3363f 389 Pfam PF00549 CoA-ligase 262 382 2.0E-24 T 22-04-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS11305 e8fb56ae1f7a05fedc8183dbf8e3363f 389 SUPERFAMILY SSF52210 239 384 1.7E-51 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS11305 e8fb56ae1f7a05fedc8183dbf8e3363f 389 Gene3D G3DSA:3.40.50.261 240 383 5.0E-65 T 22-04-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS11305 e8fb56ae1f7a05fedc8183dbf8e3363f 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 3.0E-173 T 22-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 TOLA_RS11305 e8fb56ae1f7a05fedc8183dbf8e3363f 389 PANTHER PTHR11815 1 389 9.2E-234 T 22-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 TOLA_RS11305 e8fb56ae1f7a05fedc8183dbf8e3363f 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 281 - T 22-04-2016 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 TOLA_RS11305 e8fb56ae1f7a05fedc8183dbf8e3363f 389 Gene3D G3DSA:3.30.470.20 94 239 3.0E-56 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS11305 e8fb56ae1f7a05fedc8183dbf8e3363f 389 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 42.016 T 22-04-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 TOLA_RS11305 e8fb56ae1f7a05fedc8183dbf8e3363f 389 SUPERFAMILY SSF56059 1 238 2.75E-80 T 22-04-2016 TOLA_RS09275 b4ad97ee0ebb8af7b54210af32982228 315 Gene3D G3DSA:3.40.50.1360 59 314 9.4E-73 T 22-04-2016 TOLA_RS09275 b4ad97ee0ebb8af7b54210af32982228 315 SUPERFAMILY SSF100950 63 314 3.93E-64 T 22-04-2016 TOLA_RS09275 b4ad97ee0ebb8af7b54210af32982228 315 Pfam PF04198 Putative sugar-binding domain 64 315 5.4E-59 T 22-04-2016 IPR007324 Sugar-binding domain, putative GO:0030246 TOLA_RS09275 b4ad97ee0ebb8af7b54210af32982228 315 SUPERFAMILY SSF46785 8 65 1.7E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09275 b4ad97ee0ebb8af7b54210af32982228 315 Gene3D G3DSA:1.10.10.10 20 58 6.4E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09275 b4ad97ee0ebb8af7b54210af32982228 315 PANTHER PTHR34294 6 315 8.2E-73 T 22-04-2016 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 6.7E-70 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 PIRSF PIRSF002162 1 177 6.6E-41 T 22-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 PANTHER PTHR11655 1 176 1.1E-80 T 22-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 Pfam PF00347 Ribosomal protein L6 90 164 7.8E-18 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 Pfam PF00347 Ribosomal protein L6 11 82 1.1E-15 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 34.92 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 PANTHER PTHR11655:SF14 1 176 1.1E-80 T 22-04-2016 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 22-04-2016 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 SUPERFAMILY SSF56053 1 82 1.7E-22 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 Gene3D G3DSA:3.90.930.12 2 82 2.3E-26 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 Gene3D G3DSA:3.90.930.12 83 177 3.7E-38 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 1.8E-32 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 1.8E-32 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 1.8E-32 T 22-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS00595 eb6b296e7f2b141e516b47272f505e66 177 SUPERFAMILY SSF56053 83 177 1.57E-33 T 22-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 TOLA_RS08575 82de285255edc4fa8eaa411cb8864d36 554 ProDom PD025428 SUBUNIT GLYCEROL DEHYDRATASE LARGE LYASE DHAB ALPHA DIOL B12-DEPENDENT METABOLISM 8 549 0.0 T 22-04-2016 IPR003206 Diol/glycerol dehydratase, large subunit GO:0008152|GO:0016836|GO:0031419|GO:0050215 TOLA_RS08575 82de285255edc4fa8eaa411cb8864d36 554 Gene3D G3DSA:3.20.20.350 1 553 0.0 T 22-04-2016 IPR003206 Diol/glycerol dehydratase, large subunit GO:0008152|GO:0016836|GO:0031419|GO:0050215 TOLA_RS08575 82de285255edc4fa8eaa411cb8864d36 554 PIRSF PIRSF018507 1 554 0.0 T 22-04-2016 IPR003206 Diol/glycerol dehydratase, large subunit GO:0008152|GO:0016836|GO:0031419|GO:0050215 TOLA_RS08575 82de285255edc4fa8eaa411cb8864d36 554 SUPERFAMILY SSF51703 1 553 1.29E-292 T 22-04-2016 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 TOLA_RS08575 82de285255edc4fa8eaa411cb8864d36 554 Pfam PF02286 Dehydratase large subunit 1 551 0.0 T 22-04-2016 IPR003206 Diol/glycerol dehydratase, large subunit GO:0008152|GO:0016836|GO:0031419|GO:0050215 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 PANTHER PTHR11496:SF79 360 866 0.0 T 22-04-2016 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 Gene3D G3DSA:3.40.309.10 225 273 7.3E-28 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 Gene3D G3DSA:3.40.309.10 309 404 7.3E-28 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 Pfam PF00465 Iron-containing alcohol dehydrogenase 457 848 5.6E-109 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 Gene3D G3DSA:3.40.50.1970 450 642 1.3E-57 T 22-04-2016 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 SUPERFAMILY SSF56796 451 863 3.93E-111 T 22-04-2016 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 Gene3D G3DSA:1.20.1090.10 643 863 6.9E-66 T 22-04-2016 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 PIRSF PIRSF000111 1 865 0.0 T 22-04-2016 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00592+1.1.1.1|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00650+1.2.1.10|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7085|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7180|MetaCyc: PWY-7396 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 631 659 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 719 739 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 PANTHER PTHR11496 360 866 0.0 T 22-04-2016 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 Pfam PF00171 Aldehyde dehydrogenase family 4 268 7.6E-27 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 SUPERFAMILY SSF53720 6 453 3.14E-85 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 TOLA_RS11050 d191d0aba02b240a0e6eace7f9c0d520 889 Gene3D G3DSA:3.40.605.10 2 224 1.9E-25 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 TOLA_RS15845 29c7dcd1ac454f3998ddefbbd687d8b4 317 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS15845 29c7dcd1ac454f3998ddefbbd687d8b4 317 PANTHER PTHR10683 2 316 3.8E-166 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS15845 29c7dcd1ac454f3998ddefbbd687d8b4 317 Pfam PF00923 Transaldolase 14 311 4.6E-100 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS15845 29c7dcd1ac454f3998ddefbbd687d8b4 317 Hamap MF_00492 Transaldolase [tal]. 2 316 50.256 T 22-04-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS15845 29c7dcd1ac454f3998ddefbbd687d8b4 317 TIGRFAM TIGR00874 talAB: transaldolase 4 315 3.6E-145 T 22-04-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS15845 29c7dcd1ac454f3998ddefbbd687d8b4 317 PANTHER PTHR10683:SF18 2 316 3.8E-166 T 22-04-2016 TOLA_RS15845 29c7dcd1ac454f3998ddefbbd687d8b4 317 ProSitePatterns PS00958 Transaldolase active site. 129 146 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS15845 29c7dcd1ac454f3998ddefbbd687d8b4 317 Gene3D G3DSA:3.20.20.70 3 314 6.8E-126 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS15845 29c7dcd1ac454f3998ddefbbd687d8b4 317 SUPERFAMILY SSF51569 2 315 2.83E-112 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 191 2.5E-85 T 22-04-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 SUPERFAMILY SSF52317 1 191 1.94E-54 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 Pfam PF00117 Glutamine amidotransferase class-I 3 190 3.8E-54 T 22-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 7.3E-14 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 7.3E-14 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 7.3E-14 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PANTHER PTHR11922:SF7 1 191 2.4E-94 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PANTHER PTHR11922 1 191 2.4E-94 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 Gene3D G3DSA:3.40.50.880 1 191 7.9E-67 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 7.2E-6 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 7.2E-6 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PRINTS PR00097 Anthranilate synthase component II signature 2 16 3.2E-37 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PRINTS PR00097 Anthranilate synthase component II signature 169 182 3.2E-37 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PRINTS PR00097 Anthranilate synthase component II signature 119 131 3.2E-37 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PRINTS PR00097 Anthranilate synthase component II signature 47 56 3.2E-37 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PRINTS PR00097 Anthranilate synthase component II signature 99 107 3.2E-37 T 22-04-2016 TOLA_RS14075 6d0fe5718a56098405c0e96d0a303f3f 192 PRINTS PR00097 Anthranilate synthase component II signature 74 85 3.2E-37 T 22-04-2016 TOLA_RS09025 ec07ad29298a9f627d446ae0736f5df6 197 SMART SM00987 28 184 1.5E-29 T 22-04-2016 TOLA_RS09025 ec07ad29298a9f627d446ae0736f5df6 197 PANTHER PTHR42160 1 194 1.7E-87 T 22-04-2016 TOLA_RS09025 ec07ad29298a9f627d446ae0736f5df6 197 SMART SM00986 28 184 1.5E-29 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like TOLA_RS09025 ec07ad29298a9f627d446ae0736f5df6 197 PANTHER PTHR42160:SF1 1 194 1.7E-87 T 22-04-2016 TOLA_RS09025 ec07ad29298a9f627d446ae0736f5df6 197 Gene3D G3DSA:3.40.470.10 3 191 3.2E-46 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like TOLA_RS09025 ec07ad29298a9f627d446ae0736f5df6 197 SUPERFAMILY SSF52141 3 191 2.06E-57 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like TOLA_RS09025 ec07ad29298a9f627d446ae0736f5df6 197 Pfam PF03167 Uracil DNA glycosylase superfamily 32 183 3.2E-26 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like TOLA_RS11070 8c38a8561dde6e43b4a8f02682c7aa3a 311 SUPERFAMILY SSF53335 16 296 1.3E-54 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS11070 8c38a8561dde6e43b4a8f02682c7aa3a 311 Gene3D G3DSA:3.40.50.150 108 297 6.5E-56 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS11070 8c38a8561dde6e43b4a8f02682c7aa3a 311 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 6 301 51.911 T 22-04-2016 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 TOLA_RS11070 8c38a8561dde6e43b4a8f02682c7aa3a 311 Gene3D G3DSA:1.10.8.10 15 106 2.9E-6 T 22-04-2016 TOLA_RS11070 8c38a8561dde6e43b4a8f02682c7aa3a 311 Pfam PF05175 Methyltransferase small domain 131 218 8.3E-14 T 22-04-2016 IPR007848 Methyltransferase small domain GO:0008168 TOLA_RS11070 8c38a8561dde6e43b4a8f02682c7aa3a 311 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 14 296 2.1E-129 T 22-04-2016 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 TOLA_RS11070 8c38a8561dde6e43b4a8f02682c7aa3a 311 PANTHER PTHR18895:SF66 1 299 2.6E-154 T 22-04-2016 TOLA_RS11070 8c38a8561dde6e43b4a8f02682c7aa3a 311 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 15 301 4.4E-85 T 22-04-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 TOLA_RS11070 8c38a8561dde6e43b4a8f02682c7aa3a 311 PANTHER PTHR18895 1 299 2.6E-154 T 22-04-2016 TOLA_RS11070 8c38a8561dde6e43b4a8f02682c7aa3a 311 PIRSF PIRSF037167 2 308 1.7E-140 T 22-04-2016 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 TOLA_RS11070 8c38a8561dde6e43b4a8f02682c7aa3a 311 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 205 211 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TOLA_RS14240 e9980f0fb65bbc57fec3792fd4fc9577 128 Pfam PF01042 Endoribonuclease L-PSP 9 125 1.1E-44 T 22-04-2016 IPR006175 YjgF/YER057c/UK114 family TOLA_RS14240 e9980f0fb65bbc57fec3792fd4fc9577 128 Gene3D G3DSA:3.30.1330.40 3 126 7.0E-53 T 22-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like TOLA_RS14240 e9980f0fb65bbc57fec3792fd4fc9577 128 PANTHER PTHR11803 1 128 3.6E-57 T 22-04-2016 IPR006175 YjgF/YER057c/UK114 family TOLA_RS14240 e9980f0fb65bbc57fec3792fd4fc9577 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 125 9.7E-55 T 22-04-2016 IPR006056 RidA family TOLA_RS14240 e9980f0fb65bbc57fec3792fd4fc9577 128 SUPERFAMILY SSF55298 2 126 4.56E-49 T 22-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like TOLA_RS04265 5f957399d9432fb1061f32ceba16131d 594 Pfam PF00005 ABC transporter 368 511 4.6E-24 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS04265 5f957399d9432fb1061f32ceba16131d 594 Pfam PF00664 ABC transporter transmembrane region 26 295 3.6E-35 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS04265 5f957399d9432fb1061f32ceba16131d 594 SMART SM00382 374 557 1.1E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS04265 5f957399d9432fb1061f32ceba16131d 594 Gene3D G3DSA:3.40.50.300 354 580 2.5E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04265 5f957399d9432fb1061f32ceba16131d 594 ProSitePatterns PS00211 ABC transporters family signature. 483 497 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS04265 5f957399d9432fb1061f32ceba16131d 594 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 22 552 1.9E-174 T 22-04-2016 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 TOLA_RS04265 5f957399d9432fb1061f32ceba16131d 594 SUPERFAMILY SSF90123 11 329 9.94E-48 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS04265 5f957399d9432fb1061f32ceba16131d 594 PANTHER PTHR24221 1 590 1.0E-279 T 22-04-2016 TOLA_RS04265 5f957399d9432fb1061f32ceba16131d 594 PANTHER PTHR24221:SF261 1 590 1.0E-279 T 22-04-2016 TOLA_RS04265 5f957399d9432fb1061f32ceba16131d 594 SUPERFAMILY SSF52540 344 578 2.22E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04265 5f957399d9432fb1061f32ceba16131d 594 Gene3D G3DSA:1.20.1560.10 19 329 5.5E-40 T 22-04-2016 TOLA_RS10790 45e3e140b0d6d363b708a944c44d5c15 300 SUPERFAMILY SSF46689 235 285 3.76E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS10790 45e3e140b0d6d363b708a944c44d5c15 300 PANTHER PTHR11019:SF136 19 289 2.0E-65 T 22-04-2016 TOLA_RS10790 45e3e140b0d6d363b708a944c44d5c15 300 SUPERFAMILY SSF46689 182 231 1.97E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS10790 45e3e140b0d6d363b708a944c44d5c15 300 SMART SM00342 198 281 2.1E-22 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS10790 45e3e140b0d6d363b708a944c44d5c15 300 Gene3D G3DSA:2.60.120.10 20 89 9.3E-4 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS10790 45e3e140b0d6d363b708a944c44d5c15 300 Gene3D G3DSA:1.10.10.60 179 233 2.7E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS10790 45e3e140b0d6d363b708a944c44d5c15 300 Gene3D G3DSA:1.10.10.60 234 284 1.5E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS10790 45e3e140b0d6d363b708a944c44d5c15 300 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 250 265 4.9E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS10790 45e3e140b0d6d363b708a944c44d5c15 300 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 265 281 4.9E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS10790 45e3e140b0d6d363b708a944c44d5c15 300 Pfam PF12833 Helix-turn-helix domain 205 281 8.4E-18 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS10790 45e3e140b0d6d363b708a944c44d5c15 300 PANTHER PTHR11019 19 289 2.0E-65 T 22-04-2016 TOLA_RS10280 c771fbed789bddca30a7abb1335da6c9 173 Gene3D G3DSA:3.30.1050.10 66 136 1.9E-10 T 22-04-2016 IPR003033 SCP2 sterol-binding domain TOLA_RS10280 c771fbed789bddca30a7abb1335da6c9 173 PIRSF PIRSF025550 1 172 3.5E-65 T 22-04-2016 IPR016830 Uncharacterised conserved protein UCP025550, lipid carrier protein, YhbT TOLA_RS10280 c771fbed789bddca30a7abb1335da6c9 173 Pfam PF02036 SCP-2 sterol transfer family 42 133 1.3E-16 T 22-04-2016 IPR003033 SCP2 sterol-binding domain TOLA_RS10280 c771fbed789bddca30a7abb1335da6c9 173 PANTHER PTHR10094 3 145 9.6E-53 T 22-04-2016 TOLA_RS10280 c771fbed789bddca30a7abb1335da6c9 173 SUPERFAMILY SSF55718 45 139 5.18E-17 T 22-04-2016 IPR003033 SCP2 sterol-binding domain TOLA_RS10280 c771fbed789bddca30a7abb1335da6c9 173 PANTHER PTHR10094:SF16 3 145 9.6E-53 T 22-04-2016 TOLA_RS03465 5bad52a76bea9b4ceb628370b7142342 569 Gene3D G3DSA:1.20.1560.10 32 346 2.8E-11 T 22-04-2016 TOLA_RS03465 5bad52a76bea9b4ceb628370b7142342 569 Pfam PF00005 ABC transporter 386 518 1.6E-19 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS03465 5bad52a76bea9b4ceb628370b7142342 569 ProSitePatterns PS00211 ABC transporters family signature. 490 504 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS03465 5bad52a76bea9b4ceb628370b7142342 569 Pfam PF06472 ABC transporter transmembrane region 2 10 301 2.7E-64 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS03465 5bad52a76bea9b4ceb628370b7142342 569 SUPERFAMILY SSF52540 357 559 1.07E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03465 5bad52a76bea9b4ceb628370b7142342 569 PANTHER PTHR11384 12 568 5.4E-204 T 22-04-2016 TOLA_RS03465 5bad52a76bea9b4ceb628370b7142342 569 Gene3D G3DSA:3.40.50.300 370 548 1.1E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03465 5bad52a76bea9b4ceb628370b7142342 569 SUPERFAMILY SSF90123 14 347 9.29E-25 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS03465 5bad52a76bea9b4ceb628370b7142342 569 PANTHER PTHR11384:SF3 12 568 5.4E-204 T 22-04-2016 TOLA_RS03465 5bad52a76bea9b4ceb628370b7142342 569 SMART SM00382 394 559 3.6E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS12535 d1a05cf6d86134842afae6b131e86430 495 PANTHER PTHR30203:SF15 15 492 1.9E-133 T 22-04-2016 TOLA_RS12535 d1a05cf6d86134842afae6b131e86430 495 Gene3D G3DSA:2.20.200.10 109 150 8.5E-24 T 22-04-2016 TOLA_RS12535 d1a05cf6d86134842afae6b131e86430 495 Gene3D G3DSA:2.20.200.10 323 358 8.5E-24 T 22-04-2016 TOLA_RS12535 d1a05cf6d86134842afae6b131e86430 495 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 20 473 2.5E-118 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 TOLA_RS12535 d1a05cf6d86134842afae6b131e86430 495 Pfam PF02321 Outer membrane efflux protein 73 263 2.6E-24 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS12535 d1a05cf6d86134842afae6b131e86430 495 Pfam PF02321 Outer membrane efflux protein 291 471 2.1E-33 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS12535 d1a05cf6d86134842afae6b131e86430 495 PANTHER PTHR30203 15 492 1.9E-133 T 22-04-2016 TOLA_RS12535 d1a05cf6d86134842afae6b131e86430 495 SUPERFAMILY SSF56954 12 473 6.54E-117 T 22-04-2016 TOLA_RS12535 d1a05cf6d86134842afae6b131e86430 495 Gene3D G3DSA:1.20.1600.10 62 99 1.3E-104 T 22-04-2016 TOLA_RS12535 d1a05cf6d86134842afae6b131e86430 495 Gene3D G3DSA:1.20.1600.10 360 474 1.3E-104 T 22-04-2016 TOLA_RS12535 d1a05cf6d86134842afae6b131e86430 495 Gene3D G3DSA:1.20.1600.10 151 322 1.3E-104 T 22-04-2016 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 Pfam PF00141 Peroxidase 70 397 4.2E-49 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 Pfam PF00141 Peroxidase 406 698 1.2E-36 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 11 724 0.0 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 267 290 8.3E-51 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 67 92 8.3E-51 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 478 504 8.3E-51 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 52 65 8.3E-51 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 26 48 8.3E-51 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 Gene3D G3DSA:1.10.520.10 239 251 1.9E-75 T 22-04-2016 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 Gene3D G3DSA:1.10.520.10 47 201 1.9E-75 T 22-04-2016 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 Gene3D G3DSA:1.10.520.10 434 578 7.2E-56 T 22-04-2016 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 Gene3D G3DSA:1.10.520.10 702 723 7.2E-56 T 22-04-2016 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 PANTHER PTHR30555:SF0 1 723 0.0 T 22-04-2016 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 ProSitePatterns PS00436 Peroxidases active site signature. 90 101 - T 22-04-2016 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 Gene3D G3DSA:1.10.420.10 579 699 7.2E-44 T 22-04-2016 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 PRINTS PR00458 Haem peroxidase superfamily signature 259 274 1.8E-18 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 PRINTS PR00458 Haem peroxidase superfamily signature 150 167 1.8E-18 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 PRINTS PR00458 Haem peroxidase superfamily signature 318 333 1.8E-18 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 PRINTS PR00458 Haem peroxidase superfamily signature 90 104 1.8E-18 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 PRINTS PR00458 Haem peroxidase superfamily signature 168 180 1.8E-18 T 22-04-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 Gene3D G3DSA:1.10.420.10 310 409 1.4E-45 T 22-04-2016 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 Gene3D G3DSA:1.10.420.10 252 274 1.4E-45 T 22-04-2016 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 PANTHER PTHR30555 1 723 0.0 T 22-04-2016 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 SUPERFAMILY SSF48113 18 431 2.95E-152 T 22-04-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 SUPERFAMILY SSF48113 432 722 5.45E-111 T 22-04-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 TOLA_RS05125 8fef35199fc1ed7a818fc7e40553c744 724 Hamap MF_01961 Catalase-peroxidase [katG]. 7 724 39.926 T 22-04-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 TOLA_RS07845 d9a6d5bfa53b2f68c92ce3fe3616d511 183 PANTHER PTHR35602:SF2 1 182 4.0E-116 T 22-04-2016 TOLA_RS07845 d9a6d5bfa53b2f68c92ce3fe3616d511 183 Hamap MF_01047 UPF0227 protein YcfP [ycfP]. 1 178 47.602 T 22-04-2016 IPR022987 Uncharacterised protein family UPF0227 TOLA_RS07845 d9a6d5bfa53b2f68c92ce3fe3616d511 183 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 177 9.1E-59 T 22-04-2016 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA TOLA_RS07845 d9a6d5bfa53b2f68c92ce3fe3616d511 183 PANTHER PTHR35602 1 182 4.0E-116 T 22-04-2016 TOLA_RS01215 47df52346eced5f17f22dda50e196123 600 PANTHER PTHR21000 1 599 0.0 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS01215 47df52346eced5f17f22dda50e196123 600 Pfam PF00920 Dehydratase family 65 593 3.8E-147 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS01215 47df52346eced5f17f22dda50e196123 600 SUPERFAMILY SSF52016 417 596 3.53E-54 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel TOLA_RS01215 47df52346eced5f17f22dda50e196123 600 SUPERFAMILY SSF143975 1 407 1.44E-131 T 22-04-2016 TOLA_RS01215 47df52346eced5f17f22dda50e196123 600 PANTHER PTHR21000:SF9 1 599 0.0 T 22-04-2016 TOLA_RS01215 47df52346eced5f17f22dda50e196123 600 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 5 596 1.5E-255 T 22-04-2016 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12|UniPathway: UPA00226 TOLA_RS01215 47df52346eced5f17f22dda50e196123 600 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 503 514 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS01215 47df52346eced5f17f22dda50e196123 600 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 154 164 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS15685 9d7a26dcf2e16be5727e76e6989df97c 119 Pfam PF04342 Putative member of DMT superfamily (DUF486) 8 111 3.0E-46 T 22-04-2016 IPR007437 Putative member of DMT superfamily TOLA_RS15685 9d7a26dcf2e16be5727e76e6989df97c 119 PANTHER PTHR38482 1 116 3.3E-60 T 22-04-2016 TOLA_RS15685 9d7a26dcf2e16be5727e76e6989df97c 119 PIRSF PIRSF021239 1 114 5.8E-55 T 22-04-2016 IPR007437 Putative member of DMT superfamily TOLA_RS07400 2dd636c161ea817ea1e436b0ce7b7f07 295 PANTHER PTHR12715 1 283 1.5E-55 T 22-04-2016 TOLA_RS07400 2dd636c161ea817ea1e436b0ce7b7f07 295 SUPERFAMILY SSF103481 33 135 6.93E-17 T 22-04-2016 TOLA_RS07400 2dd636c161ea817ea1e436b0ce7b7f07 295 Pfam PF00892 EamA-like transporter family 2 131 1.7E-23 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS07400 2dd636c161ea817ea1e436b0ce7b7f07 295 Pfam PF00892 EamA-like transporter family 146 276 5.5E-22 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS07400 2dd636c161ea817ea1e436b0ce7b7f07 295 SUPERFAMILY SSF103481 181 281 4.18E-16 T 22-04-2016 TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 SUPERFAMILY SSF50129 3 188 1.52E-75 T 22-04-2016 IPR011032 GroES-like TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 Gene3D G3DSA:3.40.50.720 193 312 3.7E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 SUPERFAMILY SSF50129 321 372 9.42E-13 T 22-04-2016 IPR011032 GroES-like TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 Gene3D G3DSA:3.90.180.10 3 192 7.1E-70 T 22-04-2016 IPR011032 GroES-like TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 22-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 5 371 3.7E-226 T 22-04-2016 IPR014183 Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00040+1.1.1.-|KEGG: 00051+1.1.1.-|KEGG: 00071+1.1.1.1|KEGG: 00140+1.1.1.-|KEGG: 00240+1.1.1.-|KEGG: 00253+1.1.1.-|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00362+1.1.1.-|KEGG: 00363+1.1.1.-|KEGG: 00365+1.1.1.-|KEGG: 00400+1.1.1.-|KEGG: 00520+1.1.1.-|KEGG: 00523+1.1.1.-|KEGG: 00591+1.1.1.-|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00622+1.1.1.-|KEGG: 00625+1.1.1.1+1.1.1.-|KEGG: 00626+1.1.1.1|KEGG: 00633+1.1.1.-|KEGG: 00640+1.1.1.-|KEGG: 00650+1.1.1.-|KEGG: 00680+1.1.1.284+1.1.1.-|KEGG: 00720+1.1.1.-|KEGG: 00750+1.1.1.-|KEGG: 00830+1.1.1.1+1.1.1.-|KEGG: 00950+1.1.1.-|KEGG: 00966+1.1.1.-|KEGG: 00980+1.1.1.1|KEGG: 00981+1.1.1.-|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 Pfam PF00107 Zinc-binding dehydrogenase 200 319 2.6E-23 T 22-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 157 4.5E-26 T 22-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 SUPERFAMILY SSF51735 163 337 2.56E-48 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 PANTHER PTHR11695:SF560 131 374 2.8E-215 T 22-04-2016 TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 PANTHER PTHR11695:SF560 18 111 2.8E-215 T 22-04-2016 TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 PANTHER PTHR11695 131 374 2.8E-215 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 TOLA_RS14735 26f13fa3e543c3812e319bd8b1bc3043 374 PANTHER PTHR11695 18 111 2.8E-215 T 22-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 TOLA_RS11115 48cde40924ccf07e6a69640744f99794 269 PANTHER PTHR11825 12 249 4.7E-73 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 TOLA_RS11115 48cde40924ccf07e6a69640744f99794 269 Gene3D G3DSA:3.20.10.10 125 262 3.8E-40 T 22-04-2016 TOLA_RS11115 48cde40924ccf07e6a69640744f99794 269 Pfam PF01063 Amino-transferase class IV 24 247 4.7E-43 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 TOLA_RS11115 48cde40924ccf07e6a69640744f99794 269 SUPERFAMILY SSF56752 2 257 2.62E-66 T 22-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 TOLA_RS11115 48cde40924ccf07e6a69640744f99794 269 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 3 263 6.6E-101 T 22-04-2016 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543|UniPathway: UPA00077 TOLA_RS11115 48cde40924ccf07e6a69640744f99794 269 Gene3D G3DSA:3.30.470.10 1 107 3.4E-30 T 22-04-2016 TOLA_RS11115 48cde40924ccf07e6a69640744f99794 269 PANTHER PTHR11825:SF55 12 249 4.7E-73 T 22-04-2016 TOLA_RS04540 efa30334f75410418d439bd60d18e0fc 373 Pfam PF04055 Radical SAM superfamily 109 283 1.4E-17 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS04540 efa30334f75410418d439bd60d18e0fc 373 PANTHER PTHR30544 1 373 1.8E-196 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS04540 efa30334f75410418d439bd60d18e0fc 373 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 3 358 2.7E-160 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS04540 efa30334f75410418d439bd60d18e0fc 373 PIRSF PIRSF006004 3 367 1.5E-143 T 22-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS04540 efa30334f75410418d439bd60d18e0fc 373 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 5 353 73.126 T 22-04-2016 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TOLA_RS04540 efa30334f75410418d439bd60d18e0fc 373 SUPERFAMILY SSF102114 102 312 3.53E-13 T 22-04-2016 TOLA_RS04540 efa30334f75410418d439bd60d18e0fc 373 PANTHER PTHR30544:SF5 1 373 1.8E-196 T 22-04-2016 TOLA_RS04540 efa30334f75410418d439bd60d18e0fc 373 Gene3D G3DSA:3.20.20.70 106 322 1.3E-13 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS07420 19c8b0c3db86036b04408b9db48e05f7 253 PANTHER PTHR30269 3 251 4.3E-93 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 TOLA_RS07420 19c8b0c3db86036b04408b9db48e05f7 253 PANTHER PTHR30269:SF0 3 251 4.3E-93 T 22-04-2016 TOLA_RS07420 19c8b0c3db86036b04408b9db48e05f7 253 Pfam PF01925 Sulfite exporter TauE/SafE 11 246 1.4E-46 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 TOLA_RS02420 b786a10846da99b8e7211a6beb701ef5 383 Pfam PF12832 MFS_1 like family 14 353 9.0E-44 T 22-04-2016 IPR024989 Major facilitator superfamily associated domain TOLA_RS02420 b786a10846da99b8e7211a6beb701ef5 383 SUPERFAMILY SSF103473 5 376 8.5E-34 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS02420 b786a10846da99b8e7211a6beb701ef5 383 Gene3D G3DSA:1.20.1250.20 195 373 1.2E-22 T 22-04-2016 TOLA_RS02420 b786a10846da99b8e7211a6beb701ef5 383 Gene3D G3DSA:1.20.1250.20 7 171 3.2E-12 T 22-04-2016 TOLA_RS02420 b786a10846da99b8e7211a6beb701ef5 383 PANTHER PTHR23522 1 373 6.2E-83 T 22-04-2016 TOLA_RS02420 b786a10846da99b8e7211a6beb701ef5 383 PIRSF PIRSF004925 1 383 3.2E-104 T 22-04-2016 IPR026032 Probable 3-phenylpropionic acid transporter TOLA_RS02420 b786a10846da99b8e7211a6beb701ef5 383 PANTHER PTHR23522:SF3 1 373 6.2E-83 T 22-04-2016 TOLA_RS00410 143e377c6c19ace3736814b14e11688a 368 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 264 355 5.1E-15 T 22-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal TOLA_RS00410 143e377c6c19ace3736814b14e11688a 368 SUPERFAMILY SSF52540 12 200 4.25E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00410 143e377c6c19ace3736814b14e11688a 368 SMART SM00833 264 358 4.8E-12 T 22-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal TOLA_RS00410 143e377c6c19ace3736814b14e11688a 368 PANTHER PTHR13748 257 356 2.1E-73 T 22-04-2016 TOLA_RS00410 143e377c6c19ace3736814b14e11688a 368 PANTHER PTHR13748 12 221 2.1E-73 T 22-04-2016 TOLA_RS00410 143e377c6c19ace3736814b14e11688a 368 Gene3D G3DSA:3.40.50.300 12 209 9.0E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00410 143e377c6c19ace3736814b14e11688a 368 Gene3D G3DSA:3.30.1220.10 259 355 5.2E-19 T 22-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal TOLA_RS00410 143e377c6c19ace3736814b14e11688a 368 SUPERFAMILY SSF90002 264 355 2.09E-17 T 22-04-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal TOLA_RS00410 143e377c6c19ace3736814b14e11688a 368 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 14 193 4.1E-46 T 22-04-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 Pfam PF00005 ABC transporter 28 187 4.9E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 Pfam PF00005 ABC transporter 308 459 1.1E-29 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 510 537 0.15 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 268 9.3E-4 T 22-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 SUPERFAMILY SSF52540 298 530 7.59E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 SMART SM00382 36 240 5.4E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 SMART SM00382 316 508 2.3E-17 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 PANTHER PTHR24220 9 416 2.6E-166 T 22-04-2016 TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 Gene3D G3DSA:3.40.50.300 278 532 4.6E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 PANTHER PTHR24220:SF574 9 416 2.6E-166 T 22-04-2016 TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 SUPERFAMILY SSF52540 7 259 3.04E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10780 6135c6c7afbecf9343ad690fdffe727d 539 Gene3D G3DSA:3.40.50.300 5 262 2.8E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14195 39c6423d19f7b3848318d16adac19ae6 243 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 1 240 4.1E-86 T 22-04-2016 IPR017689 Outer membrane protein assembly factor BamD TOLA_RS14195 39c6423d19f7b3848318d16adac19ae6 243 Gene3D G3DSA:1.25.40.10 21 238 4.6E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS14195 39c6423d19f7b3848318d16adac19ae6 243 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 1 236 43.689 T 22-04-2016 IPR017689 Outer membrane protein assembly factor BamD TOLA_RS14195 39c6423d19f7b3848318d16adac19ae6 243 SUPERFAMILY SSF48452 21 110 1.06E-11 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS14195 39c6423d19f7b3848318d16adac19ae6 243 Pfam PF13525 Outer membrane lipoprotein 22 228 4.8E-76 T 22-04-2016 TOLA_RS14195 39c6423d19f7b3848318d16adac19ae6 243 PANTHER PTHR37423 1 241 1.3E-92 T 22-04-2016 TOLA_RS08975 918835529fab67ad02562334eec134b9 489 TIGRFAM TIGR00886 2A0108: nitrite transporter 17 434 3.0E-97 T 22-04-2016 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 TOLA_RS08975 918835529fab67ad02562334eec134b9 489 Gene3D G3DSA:1.20.1250.20 16 200 7.9E-27 T 22-04-2016 TOLA_RS08975 918835529fab67ad02562334eec134b9 489 SUPERFAMILY SSF103473 275 473 2.18E-55 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS08975 918835529fab67ad02562334eec134b9 489 SUPERFAMILY SSF103473 12 204 2.18E-55 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS08975 918835529fab67ad02562334eec134b9 489 Gene3D G3DSA:1.20.1250.20 294 473 1.2E-22 T 22-04-2016 TOLA_RS08975 918835529fab67ad02562334eec134b9 489 PANTHER PTHR23515:SF2 5 218 1.2E-87 T 22-04-2016 TOLA_RS08975 918835529fab67ad02562334eec134b9 489 PANTHER PTHR23515:SF2 276 471 1.2E-87 T 22-04-2016 TOLA_RS08975 918835529fab67ad02562334eec134b9 489 Pfam PF07690 Major Facilitator Superfamily 23 437 1.3E-35 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS08975 918835529fab67ad02562334eec134b9 489 PANTHER PTHR23515 5 218 1.2E-87 T 22-04-2016 TOLA_RS08975 918835529fab67ad02562334eec134b9 489 PANTHER PTHR23515 276 471 1.2E-87 T 22-04-2016 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 ProSitePatterns PS00966 Phosphomannose isomerase type I signature 2. 257 282 - T 22-04-2016 IPR018050 Phosphomannose isomerase, type I, conserved site GO:0004476 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 PANTHER PTHR10309:SF0 1 373 7.6E-117 T 22-04-2016 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 Gene3D G3DSA:1.10.441.10 140 233 1.4E-25 T 22-04-2016 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 Gene3D G3DSA:1.10.441.10 276 300 1.4E-25 T 22-04-2016 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 PANTHER PTHR10309 1 373 7.6E-117 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 Gene3D G3DSA:2.60.120.10 8 139 3.4E-60 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 Gene3D G3DSA:2.60.120.10 240 275 3.4E-60 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 SUPERFAMILY SSF51182 1 375 1.5E-96 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 PIRSF PIRSF001480 1 389 1.9E-97 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 1.4E-65 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 PRINTS PR00714 Phosphomannose isomerase type I signature 125 148 1.4E-65 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 PRINTS PR00714 Phosphomannose isomerase type I signature 276 295 1.4E-65 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 PRINTS PR00714 Phosphomannose isomerase type I signature 80 101 1.4E-65 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 PRINTS PR00714 Phosphomannose isomerase type I signature 238 257 1.4E-65 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 PRINTS PR00714 Phosphomannose isomerase type I signature 222 237 1.4E-65 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 PRINTS PR00714 Phosphomannose isomerase type I signature 257 276 1.4E-65 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 1.4E-65 T 22-04-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|UniPathway: UPA00126 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 1 387 2.0E-95 T 22-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 Gene3D G3DSA:2.60.120.10 322 387 2.1E-9 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS12735 7871219465ea725d777e3b7dd7a94346 392 Pfam PF01238 Phosphomannose isomerase type I 1 357 1.5E-82 T 22-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 TOLA_RS00995 5a2f4135fee74a68b4e50a8121fbf168 237 SUPERFAMILY SSF54211 1 181 1.67E-46 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS00995 5a2f4135fee74a68b4e50a8121fbf168 237 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 5.9E-115 T 22-04-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 TOLA_RS00995 5a2f4135fee74a68b4e50a8121fbf168 237 Hamap MF_00564 Ribonuclease PH [rph]. 1 237 49.019 T 22-04-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 TOLA_RS00995 5a2f4135fee74a68b4e50a8121fbf168 237 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 1.5E-23 T 22-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 TOLA_RS00995 5a2f4135fee74a68b4e50a8121fbf168 237 SUPERFAMILY SSF55666 153 236 2.62E-26 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 TOLA_RS00995 5a2f4135fee74a68b4e50a8121fbf168 237 PANTHER PTHR11953:SF0 1 236 2.9E-87 T 22-04-2016 TOLA_RS00995 5a2f4135fee74a68b4e50a8121fbf168 237 Pfam PF03725 3' exoribonuclease family, domain 2 158 224 5.1E-12 T 22-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 TOLA_RS00995 5a2f4135fee74a68b4e50a8121fbf168 237 Gene3D G3DSA:3.30.230.70 5 236 4.1E-37 T 22-04-2016 IPR027408 PNPase/RNase PH domain TOLA_RS00995 5a2f4135fee74a68b4e50a8121fbf168 237 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 22-04-2016 IPR018336 Ribonuclease PH, conserved site TOLA_RS00995 5a2f4135fee74a68b4e50a8121fbf168 237 PANTHER PTHR11953 1 236 2.9E-87 T 22-04-2016 TOLA_RS14965 dcbf01c7d2984801b8921465cc1b7c66 115 Hamap MF_01888 Regulator of ribonuclease activity B [rraB]. 2 115 29.313 T 22-04-2016 IPR016716 Regulator of ribonuclease activity B TOLA_RS14965 dcbf01c7d2984801b8921465cc1b7c66 115 PIRSF PIRSF018193 1 115 5.0E-46 T 22-04-2016 IPR016716 Regulator of ribonuclease activity B TOLA_RS14965 dcbf01c7d2984801b8921465cc1b7c66 115 Pfam PF06877 Regulator of ribonuclease activity B 10 111 8.5E-31 T 22-04-2016 IPR009671 Regulator of ribonuclease activity B domain TOLA_RS14965 dcbf01c7d2984801b8921465cc1b7c66 115 Gene3D G3DSA:3.30.70.970 2 114 3.6E-43 T 22-04-2016 IPR009671 Regulator of ribonuclease activity B domain TOLA_RS14965 dcbf01c7d2984801b8921465cc1b7c66 115 SUPERFAMILY SSF89946 2 114 3.53E-36 T 22-04-2016 IPR009671 Regulator of ribonuclease activity B domain TOLA_RS05690 04a819e84759bd88b4b73ddd9e68509e 364 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS05690 04a819e84759bd88b4b73ddd9e68509e 364 SUPERFAMILY SSF50331 241 360 1.64E-15 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS05690 04a819e84759bd88b4b73ddd9e68509e 364 SMART SM00382 33 216 7.3E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS05690 04a819e84759bd88b4b73ddd9e68509e 364 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 39 358 2.3E-114 T 22-04-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 TOLA_RS05690 04a819e84759bd88b4b73ddd9e68509e 364 Pfam PF00005 ABC transporter 25 166 4.6E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS05690 04a819e84759bd88b4b73ddd9e68509e 364 SUPERFAMILY SSF52540 8 245 4.62E-86 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05690 04a819e84759bd88b4b73ddd9e68509e 364 Gene3D G3DSA:3.40.50.300 2 243 2.6E-79 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05690 04a819e84759bd88b4b73ddd9e68509e 364 PANTHER PTHR24220 9 364 1.2E-190 T 22-04-2016 TOLA_RS05690 04a819e84759bd88b4b73ddd9e68509e 364 Pfam PF08402 TOBE domain 283 360 5.0E-14 T 22-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 TOLA_RS05690 04a819e84759bd88b4b73ddd9e68509e 364 PANTHER PTHR24220:SF402 9 364 1.2E-190 T 22-04-2016 TOLA_RS13555 572dca3ddc9b719b51b3bb47e655aad3 410 Hamap MF_01262 CCA-adding enzyme [cca]. 1 401 43.845 T 22-04-2016 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 TOLA_RS13555 572dca3ddc9b719b51b3bb47e655aad3 410 SUPERFAMILY SSF81891 120 358 1.22E-54 T 22-04-2016 TOLA_RS13555 572dca3ddc9b719b51b3bb47e655aad3 410 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 149 212 5.8E-15 T 22-04-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain TOLA_RS13555 572dca3ddc9b719b51b3bb47e655aad3 410 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 407 52.182 T 22-04-2016 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 TOLA_RS13555 572dca3ddc9b719b51b3bb47e655aad3 410 Pfam PF01966 HD domain 242 327 1.6E-6 T 22-04-2016 IPR006674 HD domain TOLA_RS13555 572dca3ddc9b719b51b3bb47e655aad3 410 Pfam PF01743 Poly A polymerase head domain 3 122 9.1E-18 T 22-04-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 TOLA_RS13555 572dca3ddc9b719b51b3bb47e655aad3 410 PANTHER PTHR13734 1 325 2.4E-71 T 22-04-2016 TOLA_RS13555 572dca3ddc9b719b51b3bb47e655aad3 410 SUPERFAMILY SSF81301 2 119 4.58E-29 T 22-04-2016 TOLA_RS13555 572dca3ddc9b719b51b3bb47e655aad3 410 Gene3D G3DSA:3.30.460.10 2 121 3.0E-28 T 22-04-2016 TOLA_RS13555 572dca3ddc9b719b51b3bb47e655aad3 410 Gene3D G3DSA:1.10.3090.10 122 359 3.6E-57 T 22-04-2016 TOLA_RS13555 572dca3ddc9b719b51b3bb47e655aad3 410 PIRSF PIRSF000813 1 407 6.6E-191 T 22-04-2016 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 TOLA_RS15885 530b79aeff6591249851f64a09ea3095 196 Pfam PF11769 Protein of unknown function (DUF3313) 16 184 1.1E-13 T 22-04-2016 IPR021747 Protein of unknown function DUF3313 TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 SUPERFAMILY SSF56327 170 452 1.55E-37 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 PANTHER PTHR32092 1 453 8.9E-75 T 22-04-2016 TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 Gene3D G3DSA:3.90.110.10 169 452 1.2E-43 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 Pfam PF02056 Family 4 glycosyl hydrolase 4 186 1.8E-46 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 SUPERFAMILY SSF51735 4 171 9.24E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 198 425 2.3E-32 T 22-04-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 Gene3D G3DSA:3.40.50.720 2 164 1.6E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 4.5E-27 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 PRINTS PR00732 Glycosyl hydrolase family 4 signature 140 157 4.5E-27 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 PRINTS PR00732 Glycosyl hydrolase family 4 signature 73 89 4.5E-27 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 PRINTS PR00732 Glycosyl hydrolase family 4 signature 111 131 4.5E-27 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 PRINTS PR00732 Glycosyl hydrolase family 4 signature 166 177 4.5E-27 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 PRINTS PR00732 Glycosyl hydrolase family 4 signature 192 204 4.5E-27 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS10220 d5d8dff1ef57d861a883acf7a05f3f0b 453 PRINTS PR00732 Glycosyl hydrolase family 4 signature 4 19 4.5E-27 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS02070 2f0141338f1f45676572504c1a9f6079 191 Gene3D G3DSA:3.40.50.1820 3 186 2.4E-21 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS02070 2f0141338f1f45676572504c1a9f6079 191 SUPERFAMILY SSF53474 3 189 3.05E-21 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS02070 2f0141338f1f45676572504c1a9f6079 191 PANTHER PTHR35602 1 191 2.5E-85 T 22-04-2016 TOLA_RS02070 2f0141338f1f45676572504c1a9f6079 191 Pfam PF05728 Uncharacterised protein family (UPF0227) 5 189 2.1E-59 T 22-04-2016 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA TOLA_RS02070 2f0141338f1f45676572504c1a9f6079 191 PANTHER PTHR35602:SF3 1 191 2.5E-85 T 22-04-2016 TOLA_RS04180 f4e5db7391d284be0791ef39c5c5befb 305 PANTHER PTHR24220 5 304 1.6E-175 T 22-04-2016 TOLA_RS04180 f4e5db7391d284be0791ef39c5c5befb 305 SUPERFAMILY SSF52540 4 232 7.14E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04180 f4e5db7391d284be0791ef39c5c5befb 305 Pfam PF00005 ABC transporter 20 164 1.1E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS04180 f4e5db7391d284be0791ef39c5c5befb 305 PANTHER PTHR24220:SF305 5 304 1.6E-175 T 22-04-2016 TOLA_RS04180 f4e5db7391d284be0791ef39c5c5befb 305 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS04180 f4e5db7391d284be0791ef39c5c5befb 305 Gene3D G3DSA:3.40.50.300 3 227 5.7E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04180 f4e5db7391d284be0791ef39c5c5befb 305 SMART SM00382 29 212 4.5E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS11480 767b46a6d4a8080cb1d745252e462886 555 SUPERFAMILY SSF52540 284 505 1.36E-26 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11480 767b46a6d4a8080cb1d745252e462886 555 SUPERFAMILY SSF52540 3 50 1.36E-26 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11480 767b46a6d4a8080cb1d745252e462886 555 Gene3D G3DSA:3.40.50.300 432 497 7.1E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11480 767b46a6d4a8080cb1d745252e462886 555 Gene3D G3DSA:3.40.50.300 317 349 7.1E-6 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11480 767b46a6d4a8080cb1d745252e462886 555 Gene3D G3DSA:3.40.50.300 1 206 4.2E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11480 767b46a6d4a8080cb1d745252e462886 555 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 513 1.1E-20 T 22-04-2016 IPR003395 RecF/RecN/SMC, N-terminal TOLA_RS11480 767b46a6d4a8080cb1d745252e462886 555 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 552 5.4E-165 T 22-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 TOLA_RS11480 767b46a6d4a8080cb1d745252e462886 555 PANTHER PTHR11059 2 553 3.1E-175 T 22-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 TOLA_RS11480 767b46a6d4a8080cb1d745252e462886 555 SUPERFAMILY SSF52540 1 217 1.69E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11480 767b46a6d4a8080cb1d745252e462886 555 PIRSF PIRSF003128 1 555 4.6E-158 T 22-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 TOLA_RS00175 76c385e971ccb5bbe9c53f12ed5bd72e 355 PANTHER PTHR30160 1 355 1.4E-147 T 22-04-2016 TOLA_RS00175 76c385e971ccb5bbe9c53f12ed5bd72e 355 PANTHER PTHR30160:SF12 1 355 1.4E-147 T 22-04-2016 TOLA_RS00175 76c385e971ccb5bbe9c53f12ed5bd72e 355 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 74 303 3.3E-57 T 22-04-2016 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 TOLA_RS00175 76c385e971ccb5bbe9c53f12ed5bd72e 355 Gene3D G3DSA:3.40.50.2000 164 345 1.2E-45 T 22-04-2016 TOLA_RS00175 76c385e971ccb5bbe9c53f12ed5bd72e 355 SUPERFAMILY SSF53756 11 344 6.75E-83 T 22-04-2016 TOLA_RS00175 76c385e971ccb5bbe9c53f12ed5bd72e 355 Gene3D G3DSA:3.40.50.2000 13 152 2.6E-26 T 22-04-2016 TOLA_RS14525 b8e189c8235f7fc4a8c0cc3a357c50a9 87 PANTHER PTHR38036:SF1 1 87 4.1E-32 T 22-04-2016 TOLA_RS14525 b8e189c8235f7fc4a8c0cc3a357c50a9 87 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 1 87 25.636 T 22-04-2016 IPR007454 Uncharacterised protein family UPF0250 TOLA_RS14525 b8e189c8235f7fc4a8c0cc3a357c50a9 87 PANTHER PTHR38036 1 87 4.1E-32 T 22-04-2016 TOLA_RS14525 b8e189c8235f7fc4a8c0cc3a357c50a9 87 Gene3D G3DSA:3.30.70.1460 2 87 4.2E-33 T 22-04-2016 IPR027471 YbeD-like domain TOLA_RS14525 b8e189c8235f7fc4a8c0cc3a357c50a9 87 SUPERFAMILY SSF117991 1 87 3.01E-30 T 22-04-2016 IPR027471 YbeD-like domain TOLA_RS14525 b8e189c8235f7fc4a8c0cc3a357c50a9 87 Pfam PF04359 Protein of unknown function (DUF493) 7 87 3.4E-28 T 22-04-2016 IPR007454 Uncharacterised protein family UPF0250 TOLA_RS01810 71684cd4ee8f63a71e2d3303d1ae373b 172 Gene3D G3DSA:2.30.110.20 1 167 1.6E-34 T 22-04-2016 IPR008514 Type VI secretion system effector, Hcp TOLA_RS01810 71684cd4ee8f63a71e2d3303d1ae373b 172 Pfam PF05638 Type VI secretion system effector, Hcp 6 155 4.5E-34 T 22-04-2016 IPR008514 Type VI secretion system effector, Hcp TOLA_RS01810 71684cd4ee8f63a71e2d3303d1ae373b 172 PANTHER PTHR34319 1 172 1.1E-72 T 22-04-2016 TOLA_RS01810 71684cd4ee8f63a71e2d3303d1ae373b 172 SUPERFAMILY SSF141452 3 169 1.09E-44 T 22-04-2016 IPR008514 Type VI secretion system effector, Hcp TOLA_RS01810 71684cd4ee8f63a71e2d3303d1ae373b 172 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 1 168 1.1E-66 T 22-04-2016 IPR008514 Type VI secretion system effector, Hcp TOLA_RS08900 ea9f46cb83d16aa20ca48022fd349674 137 Gene3D G3DSA:3.40.630.30 29 123 3.0E-17 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS08900 ea9f46cb83d16aa20ca48022fd349674 137 SUPERFAMILY SSF55729 13 124 3.74E-14 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS08900 ea9f46cb83d16aa20ca48022fd349674 137 Pfam PF13673 Acetyltransferase (GNAT) domain 35 127 6.6E-9 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS12070 eaf9b9cf086585b3e5c196e9865bf258 155 PANTHER PTHR34390 1 155 1.4E-35 T 22-04-2016 TOLA_RS12070 eaf9b9cf086585b3e5c196e9865bf258 155 Pfam PF12821 Threonine/Serine exporter, ThrE 12 146 3.5E-34 T 22-04-2016 IPR024528 Threonine/Serine exporter, ThrE TOLA_RS13570 3116795c99f262eb2ea668ac485bd60a 196 Pfam PF02660 Glycerol-3-phosphate acyltransferase 4 177 4.3E-51 T 22-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 TOLA_RS13570 3116795c99f262eb2ea668ac485bd60a 196 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 187 1.0E-66 T 22-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 TOLA_RS13570 3116795c99f262eb2ea668ac485bd60a 196 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 1 186 18.167 T 22-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 TOLA_RS13570 3116795c99f262eb2ea668ac485bd60a 196 PANTHER PTHR30309:SF0 4 188 6.2E-82 T 22-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 TOLA_RS13570 3116795c99f262eb2ea668ac485bd60a 196 SMART SM01207 3 178 4.6E-84 T 22-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 TOLA_RS13570 3116795c99f262eb2ea668ac485bd60a 196 PANTHER PTHR30309 4 188 6.2E-82 T 22-04-2016 TOLA_RS15255 e54e0814076c130eca1cf80ffd421713 274 Gene3D G3DSA:3.40.50.1860 14 182 5.1E-46 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS15255 e54e0814076c130eca1cf80ffd421713 274 PANTHER PTHR21198:SF2 6 273 1.4E-87 T 22-04-2016 TOLA_RS15255 e54e0814076c130eca1cf80ffd421713 274 TIGRFAM TIGR00067 glut_race: glutamate racemase 15 254 1.4E-66 T 22-04-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS15255 e54e0814076c130eca1cf80ffd421713 274 PANTHER PTHR21198 6 273 1.4E-87 T 22-04-2016 TOLA_RS15255 e54e0814076c130eca1cf80ffd421713 274 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 80 88 - T 22-04-2016 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS15255 e54e0814076c130eca1cf80ffd421713 274 SUPERFAMILY SSF53681 14 116 1.05E-30 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS15255 e54e0814076c130eca1cf80ffd421713 274 SUPERFAMILY SSF53681 118 254 3.27E-30 T 22-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS15255 e54e0814076c130eca1cf80ffd421713 274 Pfam PF01177 Asp/Glu/Hydantoin racemase 17 224 2.2E-25 T 22-04-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS15255 e54e0814076c130eca1cf80ffd421713 274 Hamap MF_00258 Glutamate racemase [murI]. 13 264 31.546 T 22-04-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS15255 e54e0814076c130eca1cf80ffd421713 274 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 191 201 - T 22-04-2016 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS08735 1b21310d409dd04a833d22614c32cb9b 316 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 34 164 2.4E-62 T 22-04-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TOLA_RS08735 1b21310d409dd04a833d22614c32cb9b 316 SUPERFAMILY SSF52540 8 289 1.31E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08735 1b21310d409dd04a833d22614c32cb9b 316 PIRSF PIRSF002849 1 316 1.1E-124 T 22-04-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted TOLA_RS08735 1b21310d409dd04a833d22614c32cb9b 316 PANTHER PTHR11603:SF148 3 315 2.6E-137 T 22-04-2016 TOLA_RS08735 1b21310d409dd04a833d22614c32cb9b 316 PANTHER PTHR11603 3 315 2.6E-137 T 22-04-2016 TOLA_RS08735 1b21310d409dd04a833d22614c32cb9b 316 Gene3D G3DSA:1.10.8.300 199 313 6.7E-39 T 22-04-2016 TOLA_RS08735 1b21310d409dd04a833d22614c32cb9b 316 Gene3D G3DSA:3.40.50.300 15 180 2.1E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS16010 2eb2f9b921134317de6fe6c4a7693f17 232 Pfam PF04340 Protein of unknown function, DUF484 11 225 3.4E-41 T 22-04-2016 IPR007435 Protein of unknown function DUF484 TOLA_RS16010 2eb2f9b921134317de6fe6c4a7693f17 232 PANTHER PTHR38765 1 232 7.7E-44 T 22-04-2016 TOLA_RS07865 81c341789b1c8af2702a73c76627cf00 337 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 293 313 - T 22-04-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 TOLA_RS07865 81c341789b1c8af2702a73c76627cf00 337 Gene3D G3DSA:3.20.20.70 2 336 2.7E-129 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS07865 81c341789b1c8af2702a73c76627cf00 337 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 3 337 51.453 T 22-04-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS07865 81c341789b1c8af2702a73c76627cf00 337 Pfam PF01180 Dihydroorotate dehydrogenase 48 337 7.1E-93 T 22-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TOLA_RS07865 81c341789b1c8af2702a73c76627cf00 337 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 81 100 - T 22-04-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 TOLA_RS07865 81c341789b1c8af2702a73c76627cf00 337 SUPERFAMILY SSF51395 2 336 2.8E-108 T 22-04-2016 TOLA_RS07865 81c341789b1c8af2702a73c76627cf00 337 PIRSF PIRSF000164 15 337 3.8E-98 T 22-04-2016 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Reactome: REACT_1698 TOLA_RS07865 81c341789b1c8af2702a73c76627cf00 337 PANTHER PTHR11938 14 335 4.4E-105 T 22-04-2016 TOLA_RS07865 81c341789b1c8af2702a73c76627cf00 337 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 4 337 4.0E-151 T 22-04-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS15115 74f382e523b10f0237fd3a7d28e4832c 660 SUPERFAMILY SSF50998 322 410 3.61E-6 T 22-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TOLA_RS15115 74f382e523b10f0237fd3a7d28e4832c 660 SUPERFAMILY SSF50998 151 233 3.61E-6 T 22-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TOLA_RS15115 74f382e523b10f0237fd3a7d28e4832c 660 Pfam PF05567 Neisseria PilC beta-propeller domain 174 420 4.9E-25 T 22-04-2016 IPR008707 PilC beta-propeller domain TOLA_RS14635 345f3b14575eeeb5b9faa4a9ea83a1c6 334 SUPERFAMILY SSF51735 2 333 1.13E-88 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14635 345f3b14575eeeb5b9faa4a9ea83a1c6 334 Gene3D G3DSA:3.90.25.10 184 333 3.9E-27 T 22-04-2016 TOLA_RS14635 345f3b14575eeeb5b9faa4a9ea83a1c6 334 PANTHER PTHR10366 2 334 1.0E-178 T 22-04-2016 TOLA_RS14635 345f3b14575eeeb5b9faa4a9ea83a1c6 334 PANTHER PTHR10366:SF77 2 334 1.0E-178 T 22-04-2016 TOLA_RS14635 345f3b14575eeeb5b9faa4a9ea83a1c6 334 Gene3D G3DSA:3.40.50.720 2 183 5.9E-52 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14635 345f3b14575eeeb5b9faa4a9ea83a1c6 334 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 3.0E-29 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 TOLA_RS14635 345f3b14575eeeb5b9faa4a9ea83a1c6 334 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 3.0E-29 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 TOLA_RS14635 345f3b14575eeeb5b9faa4a9ea83a1c6 334 PRINTS PR01713 Nucleotide sugar epimerase signature 256 271 3.0E-29 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 TOLA_RS14635 345f3b14575eeeb5b9faa4a9ea83a1c6 334 PRINTS PR01713 Nucleotide sugar epimerase signature 295 312 3.0E-29 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 TOLA_RS14635 345f3b14575eeeb5b9faa4a9ea83a1c6 334 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 324 6.5E-56 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10275 fa042f0cb11ff0261a2a7f41d6b822ec 242 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 237 2.8E-84 T 22-04-2016 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 TOLA_RS10275 fa042f0cb11ff0261a2a7f41d6b822ec 242 PANTHER PTHR12029 4 179 1.6E-42 T 22-04-2016 TOLA_RS10275 fa042f0cb11ff0261a2a7f41d6b822ec 242 Pfam PF00588 SpoU rRNA Methylase family 5 154 7.8E-35 T 22-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TOLA_RS10275 fa042f0cb11ff0261a2a7f41d6b822ec 242 PIRSF PIRSF004808 1 242 2.7E-76 T 22-04-2016 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 TOLA_RS10275 fa042f0cb11ff0261a2a7f41d6b822ec 242 SUPERFAMILY SSF75217 4 176 1.57E-39 T 22-04-2016 IPR029028 Alpha/beta knot methyltransferases TOLA_RS10275 fa042f0cb11ff0261a2a7f41d6b822ec 242 Gene3D G3DSA:3.40.1280.10 4 168 1.9E-35 T 22-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TOLA_RS06105 76d4b67274588b7260feb3ed2f50a4fd 190 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 4 182 8.8E-54 T 22-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TOLA_RS06105 76d4b67274588b7260feb3ed2f50a4fd 190 Pfam PF02669 K+-transporting ATPase, c chain 5 182 4.1E-64 T 22-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TOLA_RS06105 76d4b67274588b7260feb3ed2f50a4fd 190 PIRSF PIRSF001296 1 186 2.1E-65 T 22-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TOLA_RS06105 76d4b67274588b7260feb3ed2f50a4fd 190 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 1 183 31.111 T 22-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TOLA_RS06105 76d4b67274588b7260feb3ed2f50a4fd 190 PANTHER PTHR30042 1 190 4.4E-72 T 22-04-2016 TOLA_RS06105 76d4b67274588b7260feb3ed2f50a4fd 190 PANTHER PTHR30042:SF2 1 190 4.4E-72 T 22-04-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 TOLA_RS04610 bcae37cd45bec2883ab707260625bc9d 255 Gene3D G3DSA:3.40.190.10 210 252 6.3E-44 T 22-04-2016 TOLA_RS04610 bcae37cd45bec2883ab707260625bc9d 255 Gene3D G3DSA:3.40.190.10 22 111 6.3E-44 T 22-04-2016 TOLA_RS04610 bcae37cd45bec2883ab707260625bc9d 255 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 7 248 6.4E-77 T 22-04-2016 IPR005768 Lysine-arginine-ornithine-binding periplasmic protein GO:0005215|GO:0006810|GO:0030288 TOLA_RS04610 bcae37cd45bec2883ab707260625bc9d 255 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 26 249 7.0E-60 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS04610 bcae37cd45bec2883ab707260625bc9d 255 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 48 61 - T 22-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 TOLA_RS04610 bcae37cd45bec2883ab707260625bc9d 255 SUPERFAMILY SSF53850 1 252 5.79E-68 T 22-04-2016 TOLA_RS04610 bcae37cd45bec2883ab707260625bc9d 255 PANTHER PTHR18966 21 248 1.3E-63 T 22-04-2016 TOLA_RS04610 bcae37cd45bec2883ab707260625bc9d 255 SMART SM00062 25 251 2.2E-63 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS04610 bcae37cd45bec2883ab707260625bc9d 255 PANTHER PTHR18966:SF152 21 248 1.3E-63 T 22-04-2016 TOLA_RS04610 bcae37cd45bec2883ab707260625bc9d 255 Gene3D G3DSA:3.40.190.10 115 208 5.9E-19 T 22-04-2016 TOLA_RS05350 f7f9459099c5408c22dcc6224c57fc11 104 SUPERFAMILY SSF54909 1 103 4.54E-39 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel TOLA_RS05350 f7f9459099c5408c22dcc6224c57fc11 104 TIGRFAM TIGR02625 YiiL_rotase: L-rhamnose mutarotase 3 103 2.9E-52 T 22-04-2016 IPR013448 L-rhamnose mutarotase GO:0005737|GO:0016857|GO:0019299 UniPathway: UPA00125 TOLA_RS05350 f7f9459099c5408c22dcc6224c57fc11 104 PANTHER PTHR34389:SF2 1 103 5.3E-51 T 22-04-2016 TOLA_RS05350 f7f9459099c5408c22dcc6224c57fc11 104 Hamap MF_01663 L-rhamnose mutarotase [rhaM]. 1 104 32.56 T 22-04-2016 IPR013448 L-rhamnose mutarotase GO:0005737|GO:0016857|GO:0019299 UniPathway: UPA00125 TOLA_RS05350 f7f9459099c5408c22dcc6224c57fc11 104 Pfam PF05336 Domain of unknown function (DUF718) 3 103 2.5E-30 T 22-04-2016 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 UniPathway: UPA00125 TOLA_RS05350 f7f9459099c5408c22dcc6224c57fc11 104 PANTHER PTHR34389 1 103 5.3E-51 T 22-04-2016 TOLA_RS13175 feafc31f2506e132c7be37e44e497dcb 192 Pfam PF04222 Protein of unknown function (DUF416) 6 190 2.8E-64 T 22-04-2016 IPR007338 Protein of unknown function DUF416 TOLA_RS13175 feafc31f2506e132c7be37e44e497dcb 192 Gene3D G3DSA:1.20.1590.10 4 191 5.6E-61 T 22-04-2016 IPR023381 YP001051499.1-like domain TOLA_RS01420 449eeb6c6dd4a70726dfa9f3805838c2 152 PANTHER PTHR12735:SF26 31 152 8.5E-29 T 22-04-2016 TOLA_RS01420 449eeb6c6dd4a70726dfa9f3805838c2 152 SUPERFAMILY SSF82649 18 148 1.67E-34 T 22-04-2016 TOLA_RS01420 449eeb6c6dd4a70726dfa9f3805838c2 152 Pfam PF02657 Fe-S metabolism associated domain 28 145 3.8E-34 T 22-04-2016 IPR003808 Fe-S metabolism associated domain, SufE-like UniPathway: UPA00266 TOLA_RS01420 449eeb6c6dd4a70726dfa9f3805838c2 152 Gene3D G3DSA:3.90.1010.10 20 149 8.3E-38 T 22-04-2016 TOLA_RS01420 449eeb6c6dd4a70726dfa9f3805838c2 152 PANTHER PTHR12735 31 152 8.5E-29 T 22-04-2016 TOLA_RS07330 4023985d7975880adf3efd02b47c2eef 99 Gene3D G3DSA:3.30.70.120 21 80 5.4E-4 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TOLA_RS07330 4023985d7975880adf3efd02b47c2eef 99 SUPERFAMILY SSF54913 8 97 3.34E-18 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 30 92 1.2E-13 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 Gene3D G3DSA:1.10.10.10 14 149 3.7E-42 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 Gene3D G3DSA:2.40.50.100 211 277 4.4E-25 T 22-04-2016 TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 PIRSF PIRSF005763 11 287 2.0E-85 T 22-04-2016 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 SUPERFAMILY SSF50331 218 284 4.86E-19 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 SUPERFAMILY SSF46785 26 112 3.95E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 PANTHER PTHR30432 23 125 8.4E-46 T 22-04-2016 TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 PANTHER PTHR30432 142 287 8.4E-46 T 22-04-2016 TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 Pfam PF03459 TOBE domain 149 212 5.3E-17 T 22-04-2016 IPR005116 Transport-associated OB, type 1 TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 Pfam PF03459 TOBE domain 221 282 8.5E-11 T 22-04-2016 IPR005116 Transport-associated OB, type 1 TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 SUPERFAMILY SSF50331 147 215 1.68E-20 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 218 283 1.3E-16 T 22-04-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 147 215 2.9E-24 T 22-04-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 TOLA_RS06135 33c26b52ed70f0bf3937e394f65bee09 288 Gene3D G3DSA:2.40.50.100 150 210 1.4E-25 T 22-04-2016 TOLA_RS15660 67a7f3059b18f02440effc7a4e0efe14 302 PANTHER PTHR22604 1 300 2.0E-96 T 22-04-2016 TOLA_RS15660 67a7f3059b18f02440effc7a4e0efe14 302 Gene3D G3DSA:3.30.360.10 129 301 4.2E-55 T 22-04-2016 TOLA_RS15660 67a7f3059b18f02440effc7a4e0efe14 302 PANTHER PTHR22604:SF126 1 300 2.0E-96 T 22-04-2016 TOLA_RS15660 67a7f3059b18f02440effc7a4e0efe14 302 SUPERFAMILY SSF51735 3 137 5.03E-41 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS15660 67a7f3059b18f02440effc7a4e0efe14 302 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 121 1.9E-24 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 TOLA_RS15660 67a7f3059b18f02440effc7a4e0efe14 302 SUPERFAMILY SSF55347 123 262 4.36E-35 T 22-04-2016 TOLA_RS15660 67a7f3059b18f02440effc7a4e0efe14 302 Gene3D G3DSA:3.40.50.720 1 128 9.5E-35 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS12840 d0788df752656419c9daf786783e8c4e 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 13 151 1.1E-56 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS12840 d0788df752656419c9daf786783e8c4e 156 SUPERFAMILY SSF52121 3 154 1.07E-59 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS12840 d0788df752656419c9daf786783e8c4e 156 PANTHER PTHR21058 1 154 5.4E-73 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS12840 d0788df752656419c9daf786783e8c4e 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 14 151 1.4E-56 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS12840 d0788df752656419c9daf786783e8c4e 156 Gene3D G3DSA:3.40.50.960 2 152 2.8E-64 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS12840 d0788df752656419c9daf786783e8c4e 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 154 31.348 T 22-04-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS04315 edf9b75a7db98d83ec73715ef20ce6e5 298 Gene3D G3DSA:3.30.70.1400 20 104 3.9E-32 T 22-04-2016 TOLA_RS04315 edf9b75a7db98d83ec73715ef20ce6e5 298 PANTHER PTHR22602 13 284 1.1E-60 T 22-04-2016 TOLA_RS04315 edf9b75a7db98d83ec73715ef20ce6e5 298 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 161 225 2.4E-25 T 22-04-2016 IPR017703 YgfZ/GcvT conserved site TOLA_RS04315 edf9b75a7db98d83ec73715ef20ce6e5 298 PANTHER PTHR22602:SF0 13 284 1.1E-60 T 22-04-2016 TOLA_RS04315 edf9b75a7db98d83ec73715ef20ce6e5 298 SUPERFAMILY SSF103025 5 216 7.69E-56 T 22-04-2016 TOLA_RS04315 edf9b75a7db98d83ec73715ef20ce6e5 298 SUPERFAMILY SSF101790 217 298 2.03E-17 T 22-04-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain TOLA_RS04315 edf9b75a7db98d83ec73715ef20ce6e5 298 Pfam PF01571 Aminomethyltransferase folate-binding domain 20 123 5.7E-10 T 22-04-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal TOLA_RS02665 357697068af566594f7d921498dc5825 161 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 154 29.523 T 22-04-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 TOLA_RS02665 357697068af566594f7d921498dc5825 161 PIRSF PIRSF006092 1 157 9.9E-51 T 22-04-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TOLA_RS02665 357697068af566594f7d921498dc5825 161 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 1.0E-25 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TOLA_RS02665 357697068af566594f7d921498dc5825 161 PANTHER PTHR30437 1 161 2.5E-91 T 22-04-2016 TOLA_RS02665 357697068af566594f7d921498dc5825 161 PANTHER PTHR30437:SF6 1 161 2.5E-91 T 22-04-2016 TOLA_RS02665 357697068af566594f7d921498dc5825 161 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 2 156 2.0E-74 T 22-04-2016 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 TOLA_RS02665 357697068af566594f7d921498dc5825 161 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 22-04-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TOLA_RS02665 357697068af566594f7d921498dc5825 161 Gene3D G3DSA:3.10.50.30 76 156 2.5E-31 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TOLA_RS02665 357697068af566594f7d921498dc5825 161 Hamap MF_00930 Transcription elongation factor GreB [greB]. 1 156 53.046 T 22-04-2016 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 TOLA_RS02665 357697068af566594f7d921498dc5825 161 SUPERFAMILY SSF54534 80 156 4.05E-24 T 22-04-2016 TOLA_RS02665 357697068af566594f7d921498dc5825 161 Gene3D G3DSA:1.10.287.180 1 75 5.7E-26 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TOLA_RS02665 357697068af566594f7d921498dc5825 161 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 81 155 1.8E-25 T 22-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TOLA_RS02665 357697068af566594f7d921498dc5825 161 SUPERFAMILY SSF46557 3 78 5.1E-26 T 22-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TOLA_RS02665 357697068af566594f7d921498dc5825 161 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 6 153 2.3E-42 T 22-04-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 PIRSF PIRSF005763 11 281 2.2E-88 T 22-04-2016 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 SUPERFAMILY SSF50331 142 210 2.31E-19 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 SUPERFAMILY SSF46785 23 117 2.38E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 SUPERFAMILY SSF50331 213 279 5.59E-18 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 30 92 7.4E-14 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 Gene3D G3DSA:2.40.50.100 145 207 5.9E-24 T 22-04-2016 TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 Gene3D G3DSA:2.40.50.100 208 275 4.8E-24 T 22-04-2016 TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 Gene3D G3DSA:1.10.10.10 11 144 6.3E-43 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 142 210 1.1E-21 T 22-04-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 213 278 1.4E-16 T 22-04-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 Pfam PF03459 TOBE domain 216 277 7.2E-12 T 22-04-2016 IPR005116 Transport-associated OB, type 1 TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 Pfam PF03459 TOBE domain 144 207 1.1E-15 T 22-04-2016 IPR005116 Transport-associated OB, type 1 TOLA_RS01570 aa5fa7937ef68f6527fb86506ff37a19 283 PANTHER PTHR30432 23 282 5.3E-46 T 22-04-2016 TOLA_RS04605 bca306656bd8c95ca7a9c7308d853dc3 256 SUPERFAMILY SSF52540 7 251 3.59E-75 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04605 bca306656bd8c95ca7a9c7308d853dc3 256 Gene3D G3DSA:3.40.50.300 7 253 2.6E-80 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04605 bca306656bd8c95ca7a9c7308d853dc3 256 Pfam PF00005 ABC transporter 22 181 4.4E-31 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS04605 bca306656bd8c95ca7a9c7308d853dc3 256 SMART SM00382 31 229 3.8E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS04605 bca306656bd8c95ca7a9c7308d853dc3 256 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS04605 bca306656bd8c95ca7a9c7308d853dc3 256 PANTHER PTHR24220:SF472 8 254 7.9E-150 T 22-04-2016 TOLA_RS04605 bca306656bd8c95ca7a9c7308d853dc3 256 PANTHER PTHR24220 8 254 7.9E-150 T 22-04-2016 TOLA_RS04605 bca306656bd8c95ca7a9c7308d853dc3 256 PIRSF PIRSF039085 3 256 3.9E-116 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TOLA_RS09250 7596661eeff111b4759e41b718604e92 154 PANTHER PTHR33221:SF4 2 151 1.4E-59 T 22-04-2016 TOLA_RS09250 7596661eeff111b4759e41b718604e92 154 Pfam PF02082 Transcriptional regulator 1 82 1.9E-21 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type TOLA_RS09250 7596661eeff111b4759e41b718604e92 154 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 22-04-2016 IPR030489 Transcription regulator Rrf2-type, conserved site TOLA_RS09250 7596661eeff111b4759e41b718604e92 154 PANTHER PTHR33221 2 151 1.4E-59 T 22-04-2016 TOLA_RS09250 7596661eeff111b4759e41b718604e92 154 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 1.5E-30 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type TOLA_RS09250 7596661eeff111b4759e41b718604e92 154 SUPERFAMILY SSF46785 2 133 2.03E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09250 7596661eeff111b4759e41b718604e92 154 Gene3D G3DSA:1.10.10.10 1 137 3.8E-33 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09830 c30085171d34828648fe394009a62444 368 PANTHER PTHR17630 71 368 5.1E-99 T 22-04-2016 TOLA_RS09830 c30085171d34828648fe394009a62444 368 Gene3D G3DSA:3.40.50.1820 71 368 3.6E-76 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS09830 c30085171d34828648fe394009a62444 368 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 79 213 8.3E-7 T 22-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 TOLA_RS09830 c30085171d34828648fe394009a62444 368 PANTHER PTHR17630:SF49 71 368 5.1E-99 T 22-04-2016 TOLA_RS09830 c30085171d34828648fe394009a62444 368 SUPERFAMILY SSF53474 36 210 3.03E-47 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS09830 c30085171d34828648fe394009a62444 368 SUPERFAMILY SSF53474 239 266 3.03E-47 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS09830 c30085171d34828648fe394009a62444 368 SUPERFAMILY SSF53474 296 368 3.03E-47 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS08475 2cc4e7f8c3a1492c0dc02713c32525ce 274 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS08475 2cc4e7f8c3a1492c0dc02713c32525ce 274 PANTHER PTHR24220:SF66 4 249 3.9E-81 T 22-04-2016 TOLA_RS08475 2cc4e7f8c3a1492c0dc02713c32525ce 274 Gene3D G3DSA:3.40.50.300 3 228 6.6E-66 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08475 2cc4e7f8c3a1492c0dc02713c32525ce 274 Pfam PF00005 ABC transporter 19 167 5.7E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS08475 2cc4e7f8c3a1492c0dc02713c32525ce 274 PANTHER PTHR24220 4 249 3.9E-81 T 22-04-2016 TOLA_RS08475 2cc4e7f8c3a1492c0dc02713c32525ce 274 SMART SM00382 28 211 1.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS08475 2cc4e7f8c3a1492c0dc02713c32525ce 274 SUPERFAMILY SSF52540 3 226 1.11E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08475 2cc4e7f8c3a1492c0dc02713c32525ce 274 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 12 201 7.9E-84 T 22-04-2016 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 TOLA_RS14110 fd1d90b9a2af276c1ba839812042d47e 263 Gene3D G3DSA:1.10.3130.10 10 145 5.4E-48 T 22-04-2016 TOLA_RS14110 fd1d90b9a2af276c1ba839812042d47e 263 SMART SM00971 12 116 5.0E-59 T 22-04-2016 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 TOLA_RS14110 fd1d90b9a2af276c1ba839812042d47e 263 PANTHER PTHR23416 8 262 3.8E-141 T 22-04-2016 TOLA_RS14110 fd1d90b9a2af276c1ba839812042d47e 263 Pfam PF06426 Serine acetyltransferase, N-terminal 13 116 8.5E-38 T 22-04-2016 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 TOLA_RS14110 fd1d90b9a2af276c1ba839812042d47e 263 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 205 233 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 TOLA_RS14110 fd1d90b9a2af276c1ba839812042d47e 263 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 84 245 3.6E-74 T 22-04-2016 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 TOLA_RS14110 fd1d90b9a2af276c1ba839812042d47e 263 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 196 229 2.0E-9 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS14110 fd1d90b9a2af276c1ba839812042d47e 263 SUPERFAMILY SSF51161 11 249 6.93E-65 T 22-04-2016 IPR011004 Trimeric LpxA-like TOLA_RS14110 fd1d90b9a2af276c1ba839812042d47e 263 PANTHER PTHR23416:SF2 8 262 3.8E-141 T 22-04-2016 TOLA_RS14110 fd1d90b9a2af276c1ba839812042d47e 263 Gene3D G3DSA:2.160.10.10 146 249 1.5E-31 T 22-04-2016 TOLA_RS12230 f876f159cb163fbe86f156a618bdc163 133 SUPERFAMILY SSF50249 3 121 5.83E-25 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS12230 f876f159cb163fbe86f156a618bdc163 133 Gene3D G3DSA:2.40.50.140 8 113 2.8E-21 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS12230 f876f159cb163fbe86f156a618bdc163 133 PIRSF PIRSF002070 1 133 5.0E-20 T 22-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 TOLA_RS12230 f876f159cb163fbe86f156a618bdc163 133 Pfam PF00436 Single-strand binding protein family 9 109 1.5E-11 T 22-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 TOLA_RS04545 323b465698a944709fa1d6f064e7f76b 258 Pfam PF14559 Tetratricopeptide repeat 156 215 1.1E-7 T 22-04-2016 TOLA_RS04545 323b465698a944709fa1d6f064e7f76b 258 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 10 245 1.3E-67 T 22-04-2016 IPR013360 Pilus biogenesis/stability type IV, PilW TOLA_RS04545 323b465698a944709fa1d6f064e7f76b 258 Gene3D G3DSA:1.25.40.10 42 233 2.8E-28 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS04545 323b465698a944709fa1d6f064e7f76b 258 Pfam PF13431 Tetratricopeptide repeat 65 97 6.0E-5 T 22-04-2016 TOLA_RS04545 323b465698a944709fa1d6f064e7f76b 258 SMART SM00028 42 75 0.047 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS04545 323b465698a944709fa1d6f064e7f76b 258 SMART SM00028 76 109 55.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS04545 323b465698a944709fa1d6f064e7f76b 258 SMART SM00028 146 179 0.24 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS04545 323b465698a944709fa1d6f064e7f76b 258 SMART SM00028 110 143 280.0 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS04545 323b465698a944709fa1d6f064e7f76b 258 PANTHER PTHR23083 46 250 3.2E-24 T 22-04-2016 TOLA_RS04545 323b465698a944709fa1d6f064e7f76b 258 SUPERFAMILY SSF48452 43 255 2.62E-19 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS06655 4be301a1508cb9438ddd57591a76c63c 314 PANTHER PTHR12715:SF21 1 303 3.3E-118 T 22-04-2016 TOLA_RS06655 4be301a1508cb9438ddd57591a76c63c 314 Pfam PF00892 EamA-like transporter family 3 136 9.4E-15 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS06655 4be301a1508cb9438ddd57591a76c63c 314 SUPERFAMILY SSF103481 39 143 3.47E-8 T 22-04-2016 TOLA_RS06655 4be301a1508cb9438ddd57591a76c63c 314 PANTHER PTHR12715 1 303 3.3E-118 T 22-04-2016 TOLA_RS06655 4be301a1508cb9438ddd57591a76c63c 314 SUPERFAMILY SSF103481 219 304 5.62E-5 T 22-04-2016 TOLA_RS10705 97a04aa50c08ca6fce84cb04325d54a2 398 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3 396 3.6E-164 T 22-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS10705 97a04aa50c08ca6fce84cb04325d54a2 398 PIRSF PIRSF006205 1 397 2.4E-154 T 22-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS10705 97a04aa50c08ca6fce84cb04325d54a2 398 SUPERFAMILY SSF55347 126 274 3.14E-63 T 22-04-2016 TOLA_RS10705 97a04aa50c08ca6fce84cb04325d54a2 398 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 146 239 7.8E-38 T 22-04-2016 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS10705 97a04aa50c08ca6fce84cb04325d54a2 398 Gene3D G3DSA:1.10.1740.10 312 395 5.4E-30 T 22-04-2016 TOLA_RS10705 97a04aa50c08ca6fce84cb04325d54a2 398 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 392 46.822 T 22-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS10705 97a04aa50c08ca6fce84cb04325d54a2 398 SUPERFAMILY SSF51735 3 150 1.88E-46 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10705 97a04aa50c08ca6fce84cb04325d54a2 398 Gene3D G3DSA:3.40.50.720 1 150 4.2E-54 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10705 97a04aa50c08ca6fce84cb04325d54a2 398 PANTHER PTHR30525 1 397 3.9E-220 T 22-04-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS10705 97a04aa50c08ca6fce84cb04325d54a2 398 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 132 1.7E-46 T 22-04-2016 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS10705 97a04aa50c08ca6fce84cb04325d54a2 398 Pfam PF13288 DXP reductoisomerase C-terminal domain 271 386 1.0E-40 T 22-04-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS10705 97a04aa50c08ca6fce84cb04325d54a2 398 SUPERFAMILY SSF69055 302 395 1.07E-31 T 22-04-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS01560 fdbde77835903a1b7da0a3866ede9286 361 SUPERFAMILY SSF50331 260 359 3.4E-16 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS01560 fdbde77835903a1b7da0a3866ede9286 361 SUPERFAMILY SSF52540 10 225 3.34E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01560 fdbde77835903a1b7da0a3866ede9286 361 Gene3D G3DSA:2.40.50.100 284 357 2.5E-17 T 22-04-2016 TOLA_RS01560 fdbde77835903a1b7da0a3866ede9286 361 Pfam PF03459 TOBE domain 297 359 1.1E-14 T 22-04-2016 IPR005116 Transport-associated OB, type 1 TOLA_RS01560 fdbde77835903a1b7da0a3866ede9286 361 PANTHER PTHR24220 2 229 5.3E-95 T 22-04-2016 TOLA_RS01560 fdbde77835903a1b7da0a3866ede9286 361 PANTHER PTHR24220:SF284 2 229 5.3E-95 T 22-04-2016 TOLA_RS01560 fdbde77835903a1b7da0a3866ede9286 361 Gene3D G3DSA:3.40.50.300 18 226 4.4E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01560 fdbde77835903a1b7da0a3866ede9286 361 SMART SM00382 25 211 3.6E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS01560 fdbde77835903a1b7da0a3866ede9286 361 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 5 359 7.9E-131 T 22-04-2016 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 TOLA_RS01560 fdbde77835903a1b7da0a3866ede9286 361 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS01560 fdbde77835903a1b7da0a3866ede9286 361 Pfam PF00005 ABC transporter 19 162 1.4E-25 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 253 1.9E-21 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 22-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 364 5.7E-33 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 3.5E-14 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 3.5E-14 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 3.5E-14 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 Gene3D G3DSA:3.40.120.10 250 361 1.3E-32 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 SUPERFAMILY SSF53738 155 254 3.06E-31 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 Gene3D G3DSA:3.40.120.10 175 249 5.7E-28 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 134 5.6E-46 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 PANTHER PTHR22573 2 440 4.2E-171 T 22-04-2016 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 440 5.4E-196 T 22-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 439 9.1E-15 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 Gene3D G3DSA:3.30.310.50 362 440 2.3E-17 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 443 47.904 T 22-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 Gene3D G3DSA:3.40.120.10 3 152 2.8E-49 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 SUPERFAMILY SSF53738 257 364 2.28E-31 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 SUPERFAMILY SSF53738 2 180 1.49E-49 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 PANTHER PTHR22573:SF15 2 440 4.2E-171 T 22-04-2016 TOLA_RS11430 b982f372bbe24b4baa61946455db475a 444 SUPERFAMILY SSF55957 357 443 4.32E-21 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS08710 72d96d8be639f895d3594e33b2721a0b 503 SUPERFAMILY SSF51011 372 502 3.06E-30 T 22-04-2016 TOLA_RS08710 72d96d8be639f895d3594e33b2721a0b 503 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 290 495 1.1E-39 T 22-04-2016 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55|UniPathway: UPA00667 TOLA_RS08710 72d96d8be639f895d3594e33b2721a0b 503 PANTHER PTHR31776 319 502 4.0E-205 T 22-04-2016 TOLA_RS08710 72d96d8be639f895d3594e33b2721a0b 503 PANTHER PTHR31776 264 298 4.0E-205 T 22-04-2016 TOLA_RS08710 72d96d8be639f895d3594e33b2721a0b 503 PANTHER PTHR31776 16 244 4.0E-205 T 22-04-2016 TOLA_RS08710 72d96d8be639f895d3594e33b2721a0b 503 Gene3D G3DSA:3.20.20.80 36 301 1.1E-33 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS08710 72d96d8be639f895d3594e33b2721a0b 503 SUPERFAMILY SSF51445 16 381 6.69E-114 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS08710 72d96d8be639f895d3594e33b2721a0b 503 PANTHER PTHR31776:SF1 319 502 4.0E-205 T 22-04-2016 TOLA_RS08710 72d96d8be639f895d3594e33b2721a0b 503 PANTHER PTHR31776:SF1 264 298 4.0E-205 T 22-04-2016 TOLA_RS08710 72d96d8be639f895d3594e33b2721a0b 503 PANTHER PTHR31776:SF1 16 244 4.0E-205 T 22-04-2016 TOLA_RS08710 72d96d8be639f895d3594e33b2721a0b 503 SMART SM00813 290 495 7.2E-72 T 22-04-2016 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55|UniPathway: UPA00667 TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 Pfam PF01515 Phosphate acetyl/butaryl transferase 395 709 2.3E-126 T 22-04-2016 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 SUPERFAMILY SSF53659 396 713 2.92E-94 T 22-04-2016 TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 Pfam PF13500 AAA domain 3 234 5.7E-43 T 22-04-2016 TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 Gene3D G3DSA:3.40.50.10750 528 686 6.7E-68 T 22-04-2016 TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 PIRSF PIRSF006107 1 718 0.0 T 22-04-2016 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 SUPERFAMILY SSF75138 233 357 4.19E-26 T 22-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 Pfam PF07085 DRTGG domain 237 348 2.8E-30 T 22-04-2016 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 PANTHER PTHR23406:SF3 182 715 8.0E-56 T 22-04-2016 TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 Gene3D G3DSA:3.40.50.300 3 230 5.2E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 PANTHER PTHR23406 182 715 8.0E-56 T 22-04-2016 TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 Gene3D G3DSA:3.40.1390.20 231 369 9.7E-32 T 22-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 410 709 3.4E-134 T 22-04-2016 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 TOLA_RS04500 25bed5b6e189faafbd153fe21c722f0d 718 SUPERFAMILY SSF52540 3 244 1.24E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15315 0da524f55b983ca2c5b8386533388958 113 Gene3D G3DSA:1.20.58.80 10 108 7.1E-36 T 22-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15315 0da524f55b983ca2c5b8386533388958 113 SUPERFAMILY SSF46973 9 106 4.97E-33 T 22-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15315 0da524f55b983ca2c5b8386533388958 113 PANTHER PTHR34382 2 113 2.1E-37 T 22-04-2016 TOLA_RS15315 0da524f55b983ca2c5b8386533388958 113 PANTHER PTHR34382:SF2 2 113 2.1E-37 T 22-04-2016 TOLA_RS15315 0da524f55b983ca2c5b8386533388958 113 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 14 106 9.3E-32 T 22-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15315 0da524f55b983ca2c5b8386533388958 113 PIRSF PIRSF000699 3 113 2.3E-31 T 22-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15275 bad60681cd47b8b227e2200a97b36d63 489 SUPERFAMILY SSF143968 323 487 1.7E-68 T 22-04-2016 TOLA_RS15275 bad60681cd47b8b227e2200a97b36d63 489 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 455 5.2E-174 T 22-04-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 TOLA_RS15275 bad60681cd47b8b227e2200a97b36d63 489 SUPERFAMILY SSF50475 3 322 2.16E-124 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 TOLA_RS15275 bad60681cd47b8b227e2200a97b36d63 489 PANTHER PTHR30108:SF1 1 489 5.1E-268 T 22-04-2016 TOLA_RS15275 bad60681cd47b8b227e2200a97b36d63 489 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 431 2.1E-169 T 22-04-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 TOLA_RS15275 bad60681cd47b8b227e2200a97b36d63 489 Gene3D G3DSA:1.20.5.570 455 488 1.3E-19 T 22-04-2016 TOLA_RS15275 bad60681cd47b8b227e2200a97b36d63 489 Gene3D G3DSA:3.40.1670.10 337 454 3.3E-55 T 22-04-2016 TOLA_RS15275 bad60681cd47b8b227e2200a97b36d63 489 PANTHER PTHR30108 1 489 5.1E-268 T 22-04-2016 TOLA_RS15275 bad60681cd47b8b227e2200a97b36d63 489 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 487 72.509 T 22-04-2016 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 TOLA_RS03370 91ac61732fa60252852cfea23a9180f2 228 PANTHER PTHR33937 96 222 3.1E-29 T 22-04-2016 TOLA_RS03370 91ac61732fa60252852cfea23a9180f2 228 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 105 195 5.5E-15 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS03370 91ac61732fa60252852cfea23a9180f2 228 Gene3D G3DSA:3.30.420.130 93 209 1.1E-34 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS03370 91ac61732fa60252852cfea23a9180f2 228 PANTHER PTHR33937:SF1 96 222 3.1E-29 T 22-04-2016 TOLA_RS03370 91ac61732fa60252852cfea23a9180f2 228 SUPERFAMILY SSF53146 94 209 1.57E-28 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS01650 a8023729792c5a6c1598c2d7e53c9340 325 Pfam PF03595 Voltage-dependent anion channel 19 313 8.7E-59 T 22-04-2016 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 TOLA_RS01650 a8023729792c5a6c1598c2d7e53c9340 325 PANTHER PTHR37955 9 321 6.5E-36 T 22-04-2016 TOLA_RS01650 a8023729792c5a6c1598c2d7e53c9340 325 PANTHER PTHR37955:SF1 9 321 6.5E-36 T 22-04-2016 TOLA_RS02950 ae2db4cfd42822dc34455488a6c99a94 139 SUPERFAMILY SSF102546 1 139 7.06E-43 T 22-04-2016 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 TOLA_RS02950 ae2db4cfd42822dc34455488a6c99a94 139 PANTHER PTHR37831:SF1 2 139 4.8E-62 T 22-04-2016 TOLA_RS02950 ae2db4cfd42822dc34455488a6c99a94 139 Pfam PF05025 RbsD / FucU transport protein family 1 138 2.9E-48 T 22-04-2016 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 TOLA_RS02950 ae2db4cfd42822dc34455488a6c99a94 139 Hamap MF_01661 D-ribose pyranase [rbsD]. 1 139 32.621 T 22-04-2016 IPR023064 D-ribose pyranase GO:0016872 UniPathway: UPA00916 TOLA_RS02950 ae2db4cfd42822dc34455488a6c99a94 139 PANTHER PTHR37831 2 139 4.8E-62 T 22-04-2016 TOLA_RS02950 ae2db4cfd42822dc34455488a6c99a94 139 Gene3D G3DSA:3.40.1650.10 1 139 1.4E-38 T 22-04-2016 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 TOLA_RS09565 3c3de725f934e774d5fa815d38d6c86e 60 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 5 60 3.5E-17 T 22-04-2016 IPR012933 HicA mRNA interferase family GO:0003729 TOLA_RS09565 3c3de725f934e774d5fa815d38d6c86e 60 SUPERFAMILY SSF54786 1 60 1.69E-15 T 22-04-2016 TOLA_RS09565 3c3de725f934e774d5fa815d38d6c86e 60 Gene3D G3DSA:3.30.920.30 1 60 1.3E-20 T 22-04-2016 TOLA_RS03545 ae91e7758a2aa9e376174f5897be8858 75 Pfam PF13275 S4 domain 4 68 3.8E-26 T 22-04-2016 TOLA_RS03545 ae91e7758a2aa9e376174f5897be8858 75 SUPERFAMILY SSF55174 1 67 6.15E-20 T 22-04-2016 TOLA_RS03545 ae91e7758a2aa9e376174f5897be8858 75 PANTHER PTHR32319 5 70 9.3E-25 T 22-04-2016 TOLA_RS03545 ae91e7758a2aa9e376174f5897be8858 75 PANTHER PTHR32319:SF3 5 70 9.3E-25 T 22-04-2016 TOLA_RS03545 ae91e7758a2aa9e376174f5897be8858 75 Gene3D G3DSA:3.10.290.10 1 68 1.2E-28 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS07390 61dd5390b97027e5f69ca331ad98144b 185 PANTHER PTHR11938:SF64 4 184 1.4E-79 T 22-04-2016 TOLA_RS07390 61dd5390b97027e5f69ca331ad98144b 185 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 1 184 1.4E-82 T 22-04-2016 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 TOLA_RS07390 61dd5390b97027e5f69ca331ad98144b 185 PIRSF PIRSF005784 3 185 1.9E-83 T 22-04-2016 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 TOLA_RS07390 61dd5390b97027e5f69ca331ad98144b 185 Hamap MF_00463 Electron transport complex subunit RsxB [rsxB]. 4 183 41.915 T 22-04-2016 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 TOLA_RS07390 61dd5390b97027e5f69ca331ad98144b 185 SUPERFAMILY SSF54862 37 168 3.35E-29 T 22-04-2016 TOLA_RS07390 61dd5390b97027e5f69ca331ad98144b 185 PANTHER PTHR11938 4 184 1.4E-79 T 22-04-2016 TOLA_RS07390 61dd5390b97027e5f69ca331ad98144b 185 Gene3D G3DSA:1.10.1060.10 41 119 4.1E-4 T 22-04-2016 TOLA_RS07390 61dd5390b97027e5f69ca331ad98144b 185 Pfam PF14697 4Fe-4S dicluster domain 108 162 2.0E-16 T 22-04-2016 TOLA_RS07390 61dd5390b97027e5f69ca331ad98144b 185 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 115 126 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS07390 61dd5390b97027e5f69ca331ad98144b 185 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 145 156 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS07390 61dd5390b97027e5f69ca331ad98144b 185 Gene3D G3DSA:3.30.70.20 120 174 5.2E-16 T 22-04-2016 TOLA_RS07390 61dd5390b97027e5f69ca331ad98144b 185 Pfam PF04060 Putative Fe-S cluster 44 75 1.6E-14 T 22-04-2016 IPR007202 4Fe-4S domain GO:0051536 TOLA_RS06990 fdcc7a989b76ebba01e86834d8177d54 606 PANTHER PTHR30252:SF3 3 544 1.4E-231 T 22-04-2016 TOLA_RS06990 fdcc7a989b76ebba01e86834d8177d54 606 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 417 538 2.6E-27 T 22-04-2016 IPR025299 CstA, C-terminal domain TOLA_RS06990 fdcc7a989b76ebba01e86834d8177d54 606 PANTHER PTHR30252 3 544 1.4E-231 T 22-04-2016 TOLA_RS06990 fdcc7a989b76ebba01e86834d8177d54 606 Pfam PF02554 Carbon starvation protein CstA 4 369 1.6E-134 T 22-04-2016 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 10 252 5.9E-67 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 PANTHER PTHR30481:SF3 2 277 4.5E-109 T 22-04-2016 TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 Gene3D G3DSA:3.40.50.150 1 59 5.1E-49 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 Gene3D G3DSA:3.40.50.150 160 267 5.1E-49 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 PIRSF PIRSF000398 1 273 5.3E-65 T 22-04-2016 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 Gene3D G3DSA:1.10.1020.10 60 156 1.8E-34 T 22-04-2016 IPR023095 Adenine-specific methyltransferase, domain 2 GO:0009007 TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 TIGRFAM TIGR00571 dam: DNA adenine methylase 5 267 1.1E-92 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 50 63 2.3E-17 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 31 45 2.3E-17 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 175 187 2.3E-17 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 10 26 2.3E-17 T 22-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 PANTHER PTHR30481 2 277 4.5E-109 T 22-04-2016 TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 SUPERFAMILY SSF53335 5 267 2.24E-71 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS13290 8c0656f903f9b8c4b1503c03938bc0ae 279 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 178 184 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TOLA_RS13995 0f05083218807dac29dc2819a8ced499 347 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 1 337 27.549 T 22-04-2016 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS13995 0f05083218807dac29dc2819a8ced499 347 PANTHER PTHR13326 3 335 4.9E-55 T 22-04-2016 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS13995 0f05083218807dac29dc2819a8ced499 347 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 73 86 - T 22-04-2016 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS13995 0f05083218807dac29dc2819a8ced499 347 SUPERFAMILY SSF55120 3 334 5.61E-89 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS13995 0f05083218807dac29dc2819a8ced499 347 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 13 168 1.1E-35 T 22-04-2016 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS13995 0f05083218807dac29dc2819a8ced499 347 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 186 332 7.2E-23 T 22-04-2016 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS15695 fe9a50ff5438ef5125e5650655f8b6cb 457 PANTHER PTHR11596 24 457 1.1E-162 T 22-04-2016 TOLA_RS15695 fe9a50ff5438ef5125e5650655f8b6cb 457 PRINTS PR00113 Alkaline phosphatase signature 135 155 4.8E-40 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS15695 fe9a50ff5438ef5125e5650655f8b6cb 457 PRINTS PR00113 Alkaline phosphatase signature 189 199 4.8E-40 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS15695 fe9a50ff5438ef5125e5650655f8b6cb 457 PRINTS PR00113 Alkaline phosphatase signature 25 45 4.8E-40 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS15695 fe9a50ff5438ef5125e5650655f8b6cb 457 PRINTS PR00113 Alkaline phosphatase signature 273 302 4.8E-40 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS15695 fe9a50ff5438ef5125e5650655f8b6cb 457 Pfam PF00245 Alkaline phosphatase 25 456 2.4E-109 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS15695 fe9a50ff5438ef5125e5650655f8b6cb 457 Gene3D G3DSA:3.40.720.10 14 456 9.1E-152 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 TOLA_RS15695 fe9a50ff5438ef5125e5650655f8b6cb 457 SUPERFAMILY SSF53649 16 456 1.83E-135 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 TOLA_RS15695 fe9a50ff5438ef5125e5650655f8b6cb 457 SMART SM00098 26 457 5.6E-111 T 22-04-2016 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00627+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TOLA_RS05005 6fb96c96b33b4301bdf99b6e4c7df551 540 Pfam PF13598 Domain of unknown function (DUF4139) 223 533 2.2E-82 T 22-04-2016 IPR011935 Conserved hypothetical protein CHP02231 TOLA_RS05005 6fb96c96b33b4301bdf99b6e4c7df551 540 Pfam PF13600 N-terminal domain of unknown function (DUF4140) 34 130 3.7E-19 T 22-04-2016 IPR025554 Domain of unknown function DUF4140 TOLA_RS05005 6fb96c96b33b4301bdf99b6e4c7df551 540 PANTHER PTHR31005:SF1 2 537 1.2E-72 T 22-04-2016 TOLA_RS05005 6fb96c96b33b4301bdf99b6e4c7df551 540 TIGRFAM TIGR02231 TIGR02231: conserved hypothetical protein 30 537 3.3E-97 T 22-04-2016 IPR011935 Conserved hypothetical protein CHP02231 TOLA_RS05005 6fb96c96b33b4301bdf99b6e4c7df551 540 PANTHER PTHR31005 2 537 1.2E-72 T 22-04-2016 TOLA_RS13015 6fc09415bf30a1c0b53ba5b22061f451 544 SUPERFAMILY SSF161098 289 537 4.91E-32 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS13015 6fc09415bf30a1c0b53ba5b22061f451 544 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 264 8.6E-15 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS13015 6fc09415bf30a1c0b53ba5b22061f451 544 PANTHER PTHR30183:SF2 9 392 1.4E-194 T 22-04-2016 TOLA_RS13015 6fc09415bf30a1c0b53ba5b22061f451 544 PANTHER PTHR30183:SF2 409 544 1.4E-194 T 22-04-2016 TOLA_RS13015 6fc09415bf30a1c0b53ba5b22061f451 544 Gene3D G3DSA:1.10.3720.10 15 265 3.9E-36 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS13015 6fc09415bf30a1c0b53ba5b22061f451 544 Gene3D G3DSA:1.10.3720.10 294 541 1.2E-21 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS13015 6fc09415bf30a1c0b53ba5b22061f451 544 SUPERFAMILY SSF161098 10 265 4.32E-43 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS13015 6fc09415bf30a1c0b53ba5b22061f451 544 PANTHER PTHR30183 9 392 1.4E-194 T 22-04-2016 TOLA_RS13015 6fc09415bf30a1c0b53ba5b22061f451 544 PANTHER PTHR30183 409 544 1.4E-194 T 22-04-2016 TOLA_RS00180 345dd46defe37f042dcbe20459290321 341 Gene3D G3DSA:3.40.50.2000 167 341 1.5E-56 T 22-04-2016 TOLA_RS00180 345dd46defe37f042dcbe20459290321 341 PANTHER PTHR30160 1 341 4.4E-101 T 22-04-2016 TOLA_RS00180 345dd46defe37f042dcbe20459290321 341 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 4 341 8.1E-149 T 22-04-2016 IPR011910 Lipopolysaccharide heptosyltransferase II GO:0009103|GO:0016757 KEGG: 00231+2.-.-.-|UniPathway: UPA00958 TOLA_RS00180 345dd46defe37f042dcbe20459290321 341 PANTHER PTHR30160:SF7 1 341 4.4E-101 T 22-04-2016 TOLA_RS00180 345dd46defe37f042dcbe20459290321 341 Gene3D G3DSA:3.40.50.2000 3 140 1.0E-50 T 22-04-2016 TOLA_RS00180 345dd46defe37f042dcbe20459290321 341 SUPERFAMILY SSF53756 4 340 4.39E-98 T 22-04-2016 TOLA_RS00180 345dd46defe37f042dcbe20459290321 341 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 70 323 1.8E-74 T 22-04-2016 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 Pfam PF13541 Subunit ChlI of Mg-chelatase 345 430 1.8E-9 T 22-04-2016 TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 Pfam PF13481 AAA domain 71 222 9.0E-15 T 22-04-2016 TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 PANTHER PTHR32472 1 454 4.8E-216 T 22-04-2016 TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 SUPERFAMILY SSF52540 70 289 2.33E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 Gene3D G3DSA:3.40.50.300 59 277 2.3E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 SUPERFAMILY SSF54211 303 454 1.14E-43 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 SUPERFAMILY SSF54211 255 269 1.14E-43 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 451 1.2E-215 T 22-04-2016 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 SMART SM00382 91 245 2.2E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 Gene3D G3DSA:3.30.230.10 286 454 3.4E-38 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 PRINTS PR01874 DNA repair protein radA signature 213 241 4.1E-91 T 22-04-2016 TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 PRINTS PR01874 DNA repair protein radA signature 83 111 4.1E-91 T 22-04-2016 TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 PRINTS PR01874 DNA repair protein radA signature 10 34 4.1E-91 T 22-04-2016 TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 PRINTS PR01874 DNA repair protein radA signature 174 198 4.1E-91 T 22-04-2016 TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 PRINTS PR01874 DNA repair protein radA signature 248 274 4.1E-91 T 22-04-2016 TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 PRINTS PR01874 DNA repair protein radA signature 322 345 4.1E-91 T 22-04-2016 TOLA_RS13195 df3678e14c8e5887298160baeb70c557 454 PRINTS PR01874 DNA repair protein radA signature 124 141 4.1E-91 T 22-04-2016 TOLA_RS14315 d51fb6a9012f45be88ac4da3d42ebb60 346 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 209 333 2.5E-35 T 22-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS14315 d51fb6a9012f45be88ac4da3d42ebb60 346 Pfam PF01565 FAD binding domain 45 148 4.7E-18 T 22-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TOLA_RS14315 d51fb6a9012f45be88ac4da3d42ebb60 346 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 9 334 7.7E-92 T 22-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS14315 d51fb6a9012f45be88ac4da3d42ebb60 346 PANTHER PTHR21071:SF6 1 341 6.3E-159 T 22-04-2016 TOLA_RS14315 d51fb6a9012f45be88ac4da3d42ebb60 346 PANTHER PTHR21071 1 341 6.3E-159 T 22-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS14315 d51fb6a9012f45be88ac4da3d42ebb60 346 Gene3D G3DSA:3.90.78.10 234 344 6.0E-44 T 22-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS14315 d51fb6a9012f45be88ac4da3d42ebb60 346 SUPERFAMILY SSF56194 208 342 5.36E-47 T 22-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS14315 d51fb6a9012f45be88ac4da3d42ebb60 346 Gene3D G3DSA:3.30.43.10 8 73 4.6E-17 T 22-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 TOLA_RS14315 d51fb6a9012f45be88ac4da3d42ebb60 346 Gene3D G3DSA:3.30.465.10 77 233 2.6E-52 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 TOLA_RS14315 d51fb6a9012f45be88ac4da3d42ebb60 346 SUPERFAMILY SSF56176 7 200 9.81E-41 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 TOLA_RS14315 d51fb6a9012f45be88ac4da3d42ebb60 346 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 346 82.666 T 22-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS02105 783922e0dc6ffaa5b9ebfbb4d3f40cf3 433 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 20 429 4.0E-157 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 TOLA_RS02105 783922e0dc6ffaa5b9ebfbb4d3f40cf3 433 PIRSF PIRSF015658 1 431 1.2E-172 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 TOLA_RS02105 783922e0dc6ffaa5b9ebfbb4d3f40cf3 433 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 19 425 2.6E-185 T 22-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 TOLA_RS02105 783922e0dc6ffaa5b9ebfbb4d3f40cf3 433 PANTHER PTHR35806 1 65 2.1E-199 T 22-04-2016 TOLA_RS02105 783922e0dc6ffaa5b9ebfbb4d3f40cf3 433 PANTHER PTHR35806 94 433 2.1E-199 T 22-04-2016 TOLA_RS15925 9d4280d358026ca09ec74532770f2932 434 Pfam PF02378 Phosphotransferase system, EIIC 30 349 1.5E-52 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS15925 9d4280d358026ca09ec74532770f2932 434 PIRSF PIRSF006351 2 432 1.8E-134 T 22-04-2016 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 TOLA_RS15925 9d4280d358026ca09ec74532770f2932 434 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 14 424 1.1E-110 T 22-04-2016 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 TOLA_RS15925 9d4280d358026ca09ec74532770f2932 434 PANTHER PTHR33989 1 434 3.7E-152 T 22-04-2016 TOLA_RS14355 ed4d61a636c69a3f6612f344e26fec8a 546 SMART SM00382 38 187 2.8E-6 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS14355 ed4d61a636c69a3f6612f344e26fec8a 546 PANTHER PTHR32204 1 527 9.7E-117 T 22-04-2016 TOLA_RS14355 ed4d61a636c69a3f6612f344e26fec8a 546 Pfam PF07728 AAA domain (dynein-related subfamily) 42 171 1.5E-22 T 22-04-2016 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TOLA_RS14355 ed4d61a636c69a3f6612f344e26fec8a 546 SUPERFAMILY SSF52540 22 296 1.63E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14355 ed4d61a636c69a3f6612f344e26fec8a 546 Gene3D G3DSA:3.40.50.300 25 184 7.8E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS14355 ed4d61a636c69a3f6612f344e26fec8a 546 Pfam PF12592 Protein of unknown function (DUF3763) 467 528 2.0E-19 T 22-04-2016 IPR022547 ATPase, RavA, C-terminal GO:0016820 TOLA_RS15065 954b21bd5360b6f2ba8a2db63dbcf03b 241 Pfam PF00005 ABC transporter 20 166 6.6E-35 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS15065 954b21bd5360b6f2ba8a2db63dbcf03b 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS15065 954b21bd5360b6f2ba8a2db63dbcf03b 241 PANTHER PTHR24220:SF497 5 237 5.5E-145 T 22-04-2016 TOLA_RS15065 954b21bd5360b6f2ba8a2db63dbcf03b 241 PANTHER PTHR24220 5 237 5.5E-145 T 22-04-2016 TOLA_RS15065 954b21bd5360b6f2ba8a2db63dbcf03b 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 215 236 7.6E-8 T 22-04-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TOLA_RS15065 954b21bd5360b6f2ba8a2db63dbcf03b 241 Gene3D G3DSA:3.40.50.300 2 234 1.8E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15065 954b21bd5360b6f2ba8a2db63dbcf03b 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 4 241 8.7E-121 T 22-04-2016 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 TOLA_RS15065 954b21bd5360b6f2ba8a2db63dbcf03b 241 SUPERFAMILY SSF52540 3 236 1.39E-64 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15065 954b21bd5360b6f2ba8a2db63dbcf03b 241 SMART SM00382 28 202 8.9E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS08320 6cd171df3124e3cc5089f996ec3e349b 229 PANTHER PTHR30614 1 229 1.5E-56 T 22-04-2016 TOLA_RS08320 6cd171df3124e3cc5089f996ec3e349b 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 120 1.3E-14 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 TOLA_RS08320 6cd171df3124e3cc5089f996ec3e349b 229 SUPERFAMILY SSF161098 10 211 3.92E-34 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08320 6cd171df3124e3cc5089f996ec3e349b 229 Gene3D G3DSA:1.10.3720.10 9 224 2.7E-31 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08320 6cd171df3124e3cc5089f996ec3e349b 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 216 4.7E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS01415 8b21cd07d67ac500db44fa34d583deb2 408 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 218 237 - T 22-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TOLA_RS01415 8b21cd07d67ac500db44fa34d583deb2 408 Gene3D G3DSA:3.90.1150.10 285 401 2.4E-25 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS01415 8b21cd07d67ac500db44fa34d583deb2 408 SUPERFAMILY SSF53383 4 404 1.75E-122 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS01415 8b21cd07d67ac500db44fa34d583deb2 408 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 8 406 1.7E-164 T 22-04-2016 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 TOLA_RS01415 8b21cd07d67ac500db44fa34d583deb2 408 PANTHER PTHR11601:SF17 7 408 1.8E-183 T 22-04-2016 TOLA_RS01415 8b21cd07d67ac500db44fa34d583deb2 408 PIRSF PIRSF005572 23 408 4.1E-58 T 22-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 TOLA_RS01415 8b21cd07d67ac500db44fa34d583deb2 408 Pfam PF00266 Aminotransferase class-V 26 395 1.9E-145 T 22-04-2016 IPR000192 Aminotransferase class V domain TOLA_RS01415 8b21cd07d67ac500db44fa34d583deb2 408 Gene3D G3DSA:3.40.640.10 37 284 7.4E-89 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS01415 8b21cd07d67ac500db44fa34d583deb2 408 PANTHER PTHR11601 7 408 1.8E-183 T 22-04-2016 TOLA_RS02255 f8e4930068343f63a0815c8e9149b595 248 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 2 244 32.035 T 22-04-2016 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 TOLA_RS02255 f8e4930068343f63a0815c8e9149b595 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 71 84 2.0E-5 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS02255 f8e4930068343f63a0815c8e9149b595 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 2.0E-5 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS02255 f8e4930068343f63a0815c8e9149b595 248 PRINTS PR00111 Alpha/beta hydrolase fold signature 28 43 2.0E-5 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS02255 f8e4930068343f63a0815c8e9149b595 248 PANTHER PTHR10992:SF698 4 245 1.4E-47 T 22-04-2016 TOLA_RS02255 f8e4930068343f63a0815c8e9149b595 248 Gene3D G3DSA:3.40.50.1820 2 244 2.9E-52 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS02255 f8e4930068343f63a0815c8e9149b595 248 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 3 244 1.2E-76 T 22-04-2016 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 TOLA_RS02255 f8e4930068343f63a0815c8e9149b595 248 Pfam PF12697 Alpha/beta hydrolase family 6 237 2.6E-18 T 22-04-2016 IPR000073 Alpha/beta hydrolase fold-1 TOLA_RS02255 f8e4930068343f63a0815c8e9149b595 248 SUPERFAMILY SSF53474 2 244 4.82E-43 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS02255 f8e4930068343f63a0815c8e9149b595 248 PANTHER PTHR10992 4 245 1.4E-47 T 22-04-2016 TOLA_RS04630 c72926bd36b47b2c4a842581ad480a5e 268 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 267 3.2E-99 T 22-04-2016 TOLA_RS04630 c72926bd36b47b2c4a842581ad480a5e 268 PANTHER PTHR22748:SF7 1 267 2.4E-129 T 22-04-2016 TOLA_RS04630 c72926bd36b47b2c4a842581ad480a5e 268 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 260 9.0E-28 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase TOLA_RS04630 c72926bd36b47b2c4a842581ad480a5e 268 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 22-04-2016 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 TOLA_RS04630 c72926bd36b47b2c4a842581ad480a5e 268 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 267 2.5E-86 T 22-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 TOLA_RS04630 c72926bd36b47b2c4a842581ad480a5e 268 Gene3D G3DSA:3.60.10.10 1 267 1.3E-80 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase TOLA_RS04630 c72926bd36b47b2c4a842581ad480a5e 268 PANTHER PTHR22748 1 267 2.4E-129 T 22-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 TOLA_RS04630 c72926bd36b47b2c4a842581ad480a5e 268 SUPERFAMILY SSF56219 1 267 3.4E-82 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase TOLA_RS09070 4bbf0b3956a5114a96372c4f91fc943f 105 Gene3D G3DSA:3.40.50.720 1 96 3.7E-17 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09070 4bbf0b3956a5114a96372c4f91fc943f 105 SUPERFAMILY SSF51735 1 98 2.78E-16 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09070 4bbf0b3956a5114a96372c4f91fc943f 105 Pfam PF13460 NAD(P)H-binding 8 96 1.9E-18 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09520 fb2253f4959f408e2f6c54caf43f26e2 327 TIGRFAM TIGR00825 EIIBC-GUT: PTS system, glucitol/sorbitol-specific, IIBC component 4 327 4.2E-165 T 22-04-2016 IPR004702 Phosphotransferease, sorbitol phosphotransferase enzyme II GO:0008982|GO:0009401|GO:0016021 TOLA_RS09520 fb2253f4959f408e2f6c54caf43f26e2 327 Pfam PF07663 Sorbitol phosphotransferase enzyme II C-terminus 234 326 2.8E-45 T 22-04-2016 IPR011638 Sorbitol phosphotransferase enzyme II, C-terminal GO:0008982|GO:0009401|GO:0016021 TOLA_RS09520 fb2253f4959f408e2f6c54caf43f26e2 327 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 5 179 5.0E-75 T 22-04-2016 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 TOLA_RS09520 fb2253f4959f408e2f6c54caf43f26e2 327 PANTHER PTHR39427 1 327 6.1E-117 T 22-04-2016 TOLA_RS03325 f83691be863e20578fddeba952ffa02d 443 Gene3D G3DSA:3.90.550.10 66 318 2.2E-26 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS03325 f83691be863e20578fddeba952ffa02d 443 PANTHER PTHR10859:SF92 51 425 2.6E-59 T 22-04-2016 TOLA_RS03325 f83691be863e20578fddeba952ffa02d 443 PANTHER PTHR10859 51 425 2.6E-59 T 22-04-2016 TOLA_RS03325 f83691be863e20578fddeba952ffa02d 443 Pfam PF13641 Glycosyltransferase like family 2 68 299 1.7E-20 T 22-04-2016 TOLA_RS03325 f83691be863e20578fddeba952ffa02d 443 SUPERFAMILY SSF53448 62 352 7.5E-37 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS08085 b731009ff60711a8392fbd6256fc3611 358 Pfam PF14072 DNA-sulfur modification-associated 12 345 2.1E-123 T 22-04-2016 IPR017642 DNA sulphur modification protein DndB TOLA_RS08085 b731009ff60711a8392fbd6256fc3611 358 TIGRFAM TIGR03187 DGQHR: DGQHR domain 14 289 1.9E-83 T 22-04-2016 IPR017601 DGQHR-containing domain TOLA_RS08085 b731009ff60711a8392fbd6256fc3611 358 TIGRFAM TIGR03233 DNA_S_dndB: DNA sulfur modification protein DndB 8 357 2.3E-145 T 22-04-2016 IPR017642 DNA sulphur modification protein DndB TOLA_RS02945 75d60abe195a4929a40092f43a170a52 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 247 260 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TOLA_RS02945 75d60abe195a4929a40092f43a170a52 308 TIGRFAM TIGR02152 D_ribokin_bact: ribokinase 6 300 8.3E-112 T 22-04-2016 IPR011877 Ribokinase, bacterial type GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|UniPathway: UPA00916 TOLA_RS02945 75d60abe195a4929a40092f43a170a52 308 PANTHER PTHR10584 1 305 3.2E-107 T 22-04-2016 TOLA_RS02945 75d60abe195a4929a40092f43a170a52 308 Gene3D G3DSA:3.40.1190.20 2 305 7.8E-100 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS02945 75d60abe195a4929a40092f43a170a52 308 PANTHER PTHR10584:SF166 1 305 3.2E-107 T 22-04-2016 TOLA_RS02945 75d60abe195a4929a40092f43a170a52 308 SUPERFAMILY SSF53613 3 303 3.27E-87 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS02945 75d60abe195a4929a40092f43a170a52 308 Pfam PF00294 pfkB family carbohydrate kinase 3 295 3.4E-72 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB TOLA_RS02945 75d60abe195a4929a40092f43a170a52 308 PRINTS PR00990 Ribokinase signature 218 229 7.8E-37 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS02945 75d60abe195a4929a40092f43a170a52 308 PRINTS PR00990 Ribokinase signature 174 189 7.8E-37 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS02945 75d60abe195a4929a40092f43a170a52 308 PRINTS PR00990 Ribokinase signature 34 53 7.8E-37 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS02945 75d60abe195a4929a40092f43a170a52 308 PRINTS PR00990 Ribokinase signature 7 28 7.8E-37 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS02945 75d60abe195a4929a40092f43a170a52 308 PRINTS PR00990 Ribokinase signature 106 119 7.8E-37 T 22-04-2016 IPR002139 Ribokinase GO:0004747|GO:0006014 TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 Gene3D G3DSA:1.10.530.10 95 257 4.2E-47 T 22-04-2016 TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 SUPERFAMILY SSF54106 353 397 5.89E-12 T 22-04-2016 IPR018392 LysM domain TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 SUPERFAMILY SSF53955 99 251 2.25E-42 T 22-04-2016 IPR023346 Lysozyme-like domain TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 Pfam PF01476 LysM domain 421 462 1.7E-13 T 22-04-2016 IPR018392 LysM domain TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 Pfam PF01476 LysM domain 355 396 1.2E-14 T 22-04-2016 IPR018392 LysM domain TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 SMART SM00257 420 463 1.4E-14 T 22-04-2016 IPR018392 LysM domain TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 SMART SM00257 354 397 5.8E-15 T 22-04-2016 IPR018392 LysM domain TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 PANTHER PTHR21666:SF206 355 462 1.3E-137 T 22-04-2016 TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 PANTHER PTHR21666:SF206 51 333 1.3E-137 T 22-04-2016 TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 PANTHER PTHR21666 355 462 1.3E-137 T 22-04-2016 TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 PANTHER PTHR21666 51 333 1.3E-137 T 22-04-2016 TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 Gene3D G3DSA:3.10.350.10 418 462 5.0E-18 T 22-04-2016 IPR018392 LysM domain TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 Gene3D G3DSA:3.10.350.10 354 396 8.6E-18 T 22-04-2016 IPR018392 LysM domain TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 Pfam PF01464 Transglycosylase SLT domain 110 215 5.4E-26 T 22-04-2016 IPR008258 Transglycosylase SLT domain 1 TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 SUPERFAMILY SSF54106 420 462 1.11E-11 T 22-04-2016 IPR018392 LysM domain TOLA_RS04665 53492f2d558709c985bf52f281fd3dc3 469 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 120 148 - T 22-04-2016 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 TOLA_RS03910 45c57b8dc114d146a0f96578bab3e363 197 Gene3D G3DSA:3.40.50.10070 96 192 1.7E-5 T 22-04-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 TOLA_RS03910 45c57b8dc114d146a0f96578bab3e363 197 PANTHER PTHR40593 51 197 1.0E-20 T 22-04-2016 TOLA_RS03910 45c57b8dc114d146a0f96578bab3e363 197 SUPERFAMILY SSF52964 96 190 3.66E-5 T 22-04-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 TOLA_RS03910 45c57b8dc114d146a0f96578bab3e363 197 Pfam PF13036 Peptidoglycan-synthase activator LpoB 18 195 8.5E-32 T 22-04-2016 IPR014094 Penicillin-binding protein activator LpoB TOLA_RS03910 45c57b8dc114d146a0f96578bab3e363 197 TIGRFAM TIGR02722 lp_: uncharacterized lipoprotein 12 197 7.7E-33 T 22-04-2016 IPR014094 Penicillin-binding protein activator LpoB TOLA_RS10200 d6f150d2e172e0cf6dd6c97f5e390cdb 209 SUPERFAMILY SSF53254 9 201 9.42E-39 T 22-04-2016 IPR029033 Histidine phosphatase superfamily TOLA_RS10200 d6f150d2e172e0cf6dd6c97f5e390cdb 209 SMART SM00855 9 158 1.9E-13 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 TOLA_RS10200 d6f150d2e172e0cf6dd6c97f5e390cdb 209 PANTHER PTHR23029 24 188 2.0E-32 T 22-04-2016 TOLA_RS10200 d6f150d2e172e0cf6dd6c97f5e390cdb 209 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 12 188 1.1E-37 T 22-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 TOLA_RS10200 d6f150d2e172e0cf6dd6c97f5e390cdb 209 Gene3D G3DSA:3.40.50.1240 7 188 7.7E-38 T 22-04-2016 IPR029033 Histidine phosphatase superfamily TOLA_RS10200 d6f150d2e172e0cf6dd6c97f5e390cdb 209 TIGRFAM TIGR03162 ribazole_cobC: alpha-ribazole phosphatase 10 186 5.9E-50 T 22-04-2016 IPR017578 Alpha-ribazole phosphatase, CobC GO:0009236|GO:0043755 KEGG: 00860+3.1.3.73|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 TOLA_RS10200 d6f150d2e172e0cf6dd6c97f5e390cdb 209 PANTHER PTHR23029:SF1 24 188 2.0E-32 T 22-04-2016 TOLA_RS10085 3d900acb593e3821d153ba10ba17e2c7 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 106 5.2E-29 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 TOLA_RS10085 3d900acb593e3821d153ba10ba17e2c7 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 213 7.5E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10085 3d900acb593e3821d153ba10ba17e2c7 218 Gene3D G3DSA:1.10.3720.10 9 213 4.4E-44 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10085 3d900acb593e3821d153ba10ba17e2c7 218 PANTHER PTHR30614 7 218 3.6E-86 T 22-04-2016 TOLA_RS10085 3d900acb593e3821d153ba10ba17e2c7 218 SUPERFAMILY SSF161098 13 198 1.7E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 342 362 - T 22-04-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PIRSF PIRSF000238 1 519 3.4E-266 T 22-04-2016 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 Pfam PF13192 Thioredoxin domain 125 195 5.0E-8 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 SUPERFAMILY SSF52833 1 102 3.13E-31 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 Gene3D G3DSA:3.50.50.60 338 439 1.6E-29 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PANTHER PTHR22912 199 512 1.0E-203 T 22-04-2016 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 SUPERFAMILY SSF51905 206 511 4.14E-49 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 Gene3D G3DSA:3.50.50.60 213 337 2.2E-25 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 246 261 2.0E-61 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 335 347 2.0E-61 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 276 2.0E-61 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 313 321 2.0E-61 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 350 374 2.0E-61 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 402 418 2.0E-61 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 441 462 2.0E-61 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 476 494 2.0E-61 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 214 236 2.0E-61 T 22-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 354 372 2.1E-38 T 22-04-2016 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 439 455 2.1E-38 T 22-04-2016 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 312 330 2.1E-38 T 22-04-2016 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 466 488 2.1E-38 T 22-04-2016 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 234 2.1E-38 T 22-04-2016 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 PANTHER PTHR22912:SF107 199 512 1.0E-203 T 22-04-2016 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 Gene3D G3DSA:3.50.50.60 440 511 4.7E-10 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 SUPERFAMILY SSF52833 105 197 8.22E-23 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 515 9.6E-246 T 22-04-2016 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 Gene3D G3DSA:3.40.30.10 1 94 4.2E-33 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 213 499 1.1E-45 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS02925 2cacccf693605146b2316ae545b4c121 521 Gene3D G3DSA:3.40.30.10 104 197 1.2E-36 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS10765 494b4f20516088d19a5231c588ce288a 683 SUPERFAMILY SSF53850 105 653 1.03E-77 T 22-04-2016 TOLA_RS10765 494b4f20516088d19a5231c588ce288a 683 Gene3D G3DSA:3.10.105.10 419 628 6.3E-27 T 22-04-2016 TOLA_RS10765 494b4f20516088d19a5231c588ce288a 683 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 158 560 9.5E-60 T 22-04-2016 IPR000914 Solute-binding protein family 5 domain TOLA_RS10765 494b4f20516088d19a5231c588ce288a 683 PANTHER PTHR30290 106 670 1.1E-61 T 22-04-2016 TOLA_RS10765 494b4f20516088d19a5231c588ce288a 683 Gene3D G3DSA:3.90.76.10 146 270 5.4E-26 T 22-04-2016 TOLA_RS10765 494b4f20516088d19a5231c588ce288a 683 Gene3D G3DSA:3.40.190.10 278 418 8.0E-14 T 22-04-2016 TOLA_RS02705 5e6c679c140aa499611033bd50c8e9a1 360 ProSitePatterns PS01348 MraY family signature 2. 189 200 - T 22-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS02705 5e6c679c140aa499611033bd50c8e9a1 360 PANTHER PTHR22926:SF5 2 360 1.9E-182 T 22-04-2016 TOLA_RS02705 5e6c679c140aa499611033bd50c8e9a1 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 38 360 3.3E-150 T 22-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS02705 5e6c679c140aa499611033bd50c8e9a1 360 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 22-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS02705 5e6c679c140aa499611033bd50c8e9a1 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 1.5E-5 T 22-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS02705 5e6c679c140aa499611033bd50c8e9a1 360 PANTHER PTHR22926 2 360 1.9E-182 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS02705 5e6c679c140aa499611033bd50c8e9a1 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 358 25.168 T 22-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS02705 5e6c679c140aa499611033bd50c8e9a1 360 Pfam PF00953 Glycosyl transferase family 4 99 283 6.6E-36 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS06735 74b8dcc93372343adf3ded31a43998cd 140 PANTHER PTHR35535:SF1 27 120 1.1E-16 T 22-04-2016 TOLA_RS06735 74b8dcc93372343adf3ded31a43998cd 140 PANTHER PTHR35535 27 120 1.1E-16 T 22-04-2016 TOLA_RS06735 74b8dcc93372343adf3ded31a43998cd 140 Pfam PF03724 META domain 29 133 8.2E-27 T 22-04-2016 IPR005184 Domain of unknown function DUF306, Meta/HslJ TOLA_RS13550 311f8082977691940ef5f4de7d6806d1 518 SMART SM00382 42 195 5.3E-5 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS13550 311f8082977691940ef5f4de7d6806d1 518 Gene3D G3DSA:1.10.101.10 452 509 2.5E-8 T 22-04-2016 IPR002477 Peptidoglycan binding-like TOLA_RS13550 311f8082977691940ef5f4de7d6806d1 518 PANTHER PTHR35894:SF2 2 518 6.6E-171 T 22-04-2016 TOLA_RS13550 311f8082977691940ef5f4de7d6806d1 518 SUPERFAMILY SSF52540 9 261 1.02E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13550 311f8082977691940ef5f4de7d6806d1 518 Gene3D G3DSA:3.40.50.300 26 184 1.3E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13550 311f8082977691940ef5f4de7d6806d1 518 Pfam PF01471 Putative peptidoglycan binding domain 453 505 9.1E-9 T 22-04-2016 IPR002477 Peptidoglycan binding-like TOLA_RS13550 311f8082977691940ef5f4de7d6806d1 518 SUPERFAMILY SSF47090 453 510 1.04E-7 T 22-04-2016 IPR002477 Peptidoglycan binding-like TOLA_RS13550 311f8082977691940ef5f4de7d6806d1 518 PANTHER PTHR35894 2 518 6.6E-171 T 22-04-2016 TOLA_RS13550 311f8082977691940ef5f4de7d6806d1 518 Pfam PF13401 AAA domain 42 171 5.7E-23 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 Pfam PF01726 LexA DNA binding domain 1 65 5.6E-30 T 22-04-2016 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 Gene3D G3DSA:2.10.109.10 79 202 6.0E-43 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 Gene3D G3DSA:1.10.10.10 1 69 2.0E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 TIGRFAM TIGR00498 lexA: repressor LexA 1 203 3.7E-80 T 22-04-2016 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 Pfam PF00717 Peptidase S24-like 117 183 7.4E-14 T 22-04-2016 IPR019759 Peptidase S24/S26A/S26B TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 SUPERFAMILY SSF51306 79 202 2.27E-35 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 SUPERFAMILY SSF46785 3 69 1.11E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 Hamap MF_00015 LexA repressor [lexA]. 3 203 32.874 T 22-04-2016 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 PANTHER PTHR33516 1 206 1.5E-103 T 22-04-2016 TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 PANTHER PTHR33516:SF2 1 206 1.5E-103 T 22-04-2016 TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 125 136 3.2E-13 T 22-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 154 166 3.2E-13 T 22-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 TOLA_RS00755 838b5d89339eff0e3bf999b4d8d9d73d 206 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 114 124 3.2E-13 T 22-04-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 TOLA_RS05525 78afca0fbfd8860a5adc8e5030de7457 380 PANTHER PTHR22976 3 367 4.1E-186 T 22-04-2016 TOLA_RS05525 78afca0fbfd8860a5adc8e5030de7457 380 Pfam PF04055 Radical SAM superfamily 86 230 5.4E-8 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS05525 78afca0fbfd8860a5adc8e5030de7457 380 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 260 362 1.6E-24 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 TOLA_RS05525 78afca0fbfd8860a5adc8e5030de7457 380 TIGRFAM TIGR02351 thiH: thiazole biosynthesis protein ThiH 2 368 9.3E-159 T 22-04-2016 IPR012726 Thiazole biosynthesis ThiH GO:0005506|GO:0009228|GO:0051539 KEGG: 00730+4.1.99.19|MetaCyc: PWY-6892|UniPathway: UPA00060 TOLA_RS05525 78afca0fbfd8860a5adc8e5030de7457 380 SMART SM00876 260 363 2.3E-34 T 22-04-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 TOLA_RS05525 78afca0fbfd8860a5adc8e5030de7457 380 Gene3D G3DSA:3.20.20.70 45 362 2.2E-47 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS05525 78afca0fbfd8860a5adc8e5030de7457 380 SUPERFAMILY SSF102114 45 333 4.45E-53 T 22-04-2016 TOLA_RS05525 78afca0fbfd8860a5adc8e5030de7457 380 PANTHER PTHR22976:SF17 3 367 4.1E-186 T 22-04-2016 TOLA_RS07765 6d45746d035b2f786fc43dd6d301fd36 201 SUPERFAMILY SSF52218 1 198 5.94E-48 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS07765 6d45746d035b2f786fc43dd6d301fd36 201 Pfam PF02525 Flavodoxin-like fold 3 196 3.0E-42 T 22-04-2016 IPR003680 Flavodoxin-like fold TOLA_RS07765 6d45746d035b2f786fc43dd6d301fd36 201 PANTHER PTHR10204 1 200 4.1E-71 T 22-04-2016 TOLA_RS07765 6d45746d035b2f786fc43dd6d301fd36 201 Gene3D G3DSA:3.40.50.360 1 197 5.3E-59 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS07765 6d45746d035b2f786fc43dd6d301fd36 201 PANTHER PTHR10204:SF16 1 200 4.1E-71 T 22-04-2016 TOLA_RS07765 6d45746d035b2f786fc43dd6d301fd36 201 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 198 29.116 T 22-04-2016 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 TOLA_RS08755 369a619e687712393d273fe4fa7aeefc 482 Pfam PF00515 Tetratricopeptide repeat 383 414 2.9E-9 T 22-04-2016 IPR001440 Tetratricopeptide repeat 1 GO:0005515 TOLA_RS08755 369a619e687712393d273fe4fa7aeefc 482 SMART SM00028 381 414 4.2E-8 T 22-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 TOLA_RS08755 369a619e687712393d273fe4fa7aeefc 482 Pfam PF13519 von Willebrand factor type A domain 90 196 1.0E-12 T 22-04-2016 IPR002035 von Willebrand factor, type A TOLA_RS08755 369a619e687712393d273fe4fa7aeefc 482 SUPERFAMILY SSF48452 339 461 1.16E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS08755 369a619e687712393d273fe4fa7aeefc 482 SUPERFAMILY SSF53300 106 226 6.47E-13 T 22-04-2016 IPR002035 von Willebrand factor, type A TOLA_RS08755 369a619e687712393d273fe4fa7aeefc 482 Gene3D G3DSA:1.25.40.10 329 460 2.6E-16 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS06845 97bd8c547aaea3cd41e8d479c575cf32 269 Pfam PF00795 Carbon-nitrogen hydrolase 5 238 8.0E-41 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS06845 97bd8c547aaea3cd41e8d479c575cf32 269 PANTHER PTHR23088 1 260 3.1E-59 T 22-04-2016 TOLA_RS06845 97bd8c547aaea3cd41e8d479c575cf32 269 PANTHER PTHR23088:SF27 1 260 3.1E-59 T 22-04-2016 TOLA_RS06845 97bd8c547aaea3cd41e8d479c575cf32 269 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 136 156 - T 22-04-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site TOLA_RS06845 97bd8c547aaea3cd41e8d479c575cf32 269 Gene3D G3DSA:3.60.110.10 1 256 2.6E-65 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS06845 97bd8c547aaea3cd41e8d479c575cf32 269 SUPERFAMILY SSF56317 1 249 1.7E-63 T 22-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 TOLA_RS06315 06acb92fc5b31ff00c413281de94ce1e 333 Gene3D G3DSA:1.10.3720.10 33 317 2.3E-63 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06315 06acb92fc5b31ff00c413281de94ce1e 333 PANTHER PTHR30406:SF2 8 333 6.9E-98 T 22-04-2016 TOLA_RS06315 06acb92fc5b31ff00c413281de94ce1e 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 317 1.3E-23 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06315 06acb92fc5b31ff00c413281de94ce1e 333 SUPERFAMILY SSF161098 97 314 1.14E-59 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06315 06acb92fc5b31ff00c413281de94ce1e 333 PANTHER PTHR30406 8 333 6.9E-98 T 22-04-2016 TOLA_RS12695 9eeac8e6476eac3e652626ae546cb04d 116 Gene3D G3DSA:1.20.1300.10 2 115 3.7E-43 T 22-04-2016 TOLA_RS12695 9eeac8e6476eac3e652626ae546cb04d 116 SUPERFAMILY SSF81343 2 114 5.4E-38 T 22-04-2016 TOLA_RS12695 9eeac8e6476eac3e652626ae546cb04d 116 ProDom PD015693 FUMARATE MEMBRANE REDUCTASE D SUBUNIT INNER TRANSMEMBRANE HYDROPHOBIC REDUCTASE POLYPEPTIDE 2 115 2.0E-19 T 22-04-2016 IPR003418 Fumarate reductase, D subunit GO:0006106|GO:0016020 TOLA_RS12695 9eeac8e6476eac3e652626ae546cb04d 116 Pfam PF02313 Fumarate reductase subunit D 1 112 5.4E-45 T 22-04-2016 IPR003418 Fumarate reductase, D subunit GO:0006106|GO:0016020 TOLA_RS12695 9eeac8e6476eac3e652626ae546cb04d 116 PIRSF PIRSF000179 1 115 2.6E-43 T 22-04-2016 IPR003418 Fumarate reductase, D subunit GO:0006106|GO:0016020 TOLA_RS04655 17958c355e7f5e29ae7efd01d06669ce 110 Pfam PF08921 Domain of unknown function (DUF1904) 1 109 3.4E-32 T 22-04-2016 IPR015017 Protein of unknown function DUF1904 TOLA_RS04655 17958c355e7f5e29ae7efd01d06669ce 110 Gene3D G3DSA:3.30.429.10 1 110 2.0E-40 T 22-04-2016 TOLA_RS04655 17958c355e7f5e29ae7efd01d06669ce 110 SUPERFAMILY SSF55331 1 110 3.51E-31 T 22-04-2016 IPR014347 Tautomerase/MIF superfamily TOLA_RS01485 a56b6870aa96f05088a4f76b3b7a0317 561 Pfam PF00990 Diguanylate cyclase, GGDEF domain 383 542 8.7E-47 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS01485 a56b6870aa96f05088a4f76b3b7a0317 561 Gene3D G3DSA:3.40.190.10 121 187 9.3E-4 T 22-04-2016 TOLA_RS01485 a56b6870aa96f05088a4f76b3b7a0317 561 PANTHER PTHR31528 1 336 1.0E-49 T 22-04-2016 IPR027939 NMT1/THI5 family GO:0009228 UniPathway: UPA00060 TOLA_RS01485 a56b6870aa96f05088a4f76b3b7a0317 561 Gene3D G3DSA:3.30.70.270 384 549 2.4E-52 T 22-04-2016 TOLA_RS01485 a56b6870aa96f05088a4f76b3b7a0317 561 SUPERFAMILY SSF53850 41 272 7.88E-25 T 22-04-2016 TOLA_RS01485 a56b6870aa96f05088a4f76b3b7a0317 561 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 379 545 7.8E-49 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS01485 a56b6870aa96f05088a4f76b3b7a0317 561 SUPERFAMILY SSF55073 387 547 4.63E-47 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS01485 a56b6870aa96f05088a4f76b3b7a0317 561 Pfam PF09084 NMT1/THI5 like 45 256 7.6E-46 T 22-04-2016 IPR015168 SsuA/THI5-like TOLA_RS01485 a56b6870aa96f05088a4f76b3b7a0317 561 SMART SM00267 371 546 5.5E-62 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 Gene3D G3DSA:3.40.120.10 172 254 1.3E-29 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 SUPERFAMILY SSF53738 153 261 1.15E-27 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 SUPERFAMILY SSF53738 5 176 3.83E-39 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 Gene3D G3DSA:3.30.310.50 374 453 4.2E-16 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 209 222 2.7E-30 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 170 189 2.7E-30 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 238 253 2.7E-30 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 2.7E-30 T 22-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 263 373 8.6E-26 T 22-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 153 258 6.7E-24 T 22-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 134 8.7E-32 T 22-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 PANTHER PTHR22573:SF18 7 454 5.8E-186 T 22-04-2016 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 Gene3D G3DSA:3.40.120.10 255 368 1.3E-39 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 Gene3D G3DSA:3.40.120.10 7 139 1.0E-33 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 440 3.1E-8 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 SUPERFAMILY SSF55957 373 440 2.96E-16 T 22-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 SUPERFAMILY SSF53738 263 367 4.71E-32 T 22-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 92 101 - T 22-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TOLA_RS10415 ac47dba7b6ab35c8f5394c2c776d74dc 456 PANTHER PTHR22573 7 454 5.8E-186 T 22-04-2016 TOLA_RS14535 a02ddad2ffbe86ed464110ffad1bcfe0 321 PIRSF PIRSF005963 6 321 4.9E-129 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 TOLA_RS14535 a02ddad2ffbe86ed464110ffad1bcfe0 321 SUPERFAMILY SSF102114 49 315 5.49E-65 T 22-04-2016 TOLA_RS14535 a02ddad2ffbe86ed464110ffad1bcfe0 321 Pfam PF04055 Radical SAM superfamily 91 251 6.4E-15 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS14535 a02ddad2ffbe86ed464110ffad1bcfe0 321 SMART SM00729 84 293 2.7E-15 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TOLA_RS14535 a02ddad2ffbe86ed464110ffad1bcfe0 321 Hamap MF_00206 Lipoyl synthase [lipA]. 1 321 153.192 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 TOLA_RS14535 a02ddad2ffbe86ed464110ffad1bcfe0 321 PANTHER PTHR10949 10 321 1.6E-174 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 TOLA_RS14535 a02ddad2ffbe86ed464110ffad1bcfe0 321 Gene3D G3DSA:3.20.20.70 53 312 4.4E-68 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS14535 a02ddad2ffbe86ed464110ffad1bcfe0 321 TIGRFAM TIGR00510 lipA: lipoyl synthase 21 321 3.4E-146 T 22-04-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 TOLA_RS14535 a02ddad2ffbe86ed464110ffad1bcfe0 321 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 29 73 5.5E-7 T 22-04-2016 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 TOLA_RS00200 9a701f28f29ac444e509f8af9dc67227 291 Pfam PF07148 Maltose operon periplasmic protein precursor (MalM) 67 200 5.4E-50 T 22-04-2016 IPR010794 Maltose operon periplasmic GO:0008643|GO:0042597 TOLA_RS04330 d0bd819c77c822bb345b2ce5b31ae01f 194 PANTHER PTHR30173 1 191 7.3E-55 T 22-04-2016 TOLA_RS04330 d0bd819c77c822bb345b2ce5b31ae01f 194 Pfam PF08281 Sigma-70, region 4 132 180 1.0E-19 T 22-04-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS04330 d0bd819c77c822bb345b2ce5b31ae01f 194 SUPERFAMILY SSF88659 125 186 1.63E-18 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS04330 d0bd819c77c822bb345b2ce5b31ae01f 194 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 1 190 9.7E-94 T 22-04-2016 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS04330 d0bd819c77c822bb345b2ce5b31ae01f 194 Gene3D G3DSA:1.10.1740.10 6 111 6.7E-36 T 22-04-2016 TOLA_RS04330 d0bd819c77c822bb345b2ce5b31ae01f 194 Gene3D G3DSA:1.10.10.10 125 187 5.6E-26 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS04330 d0bd819c77c822bb345b2ce5b31ae01f 194 Pfam PF04542 Sigma-70 region 2 25 92 7.1E-18 T 22-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS04330 d0bd819c77c822bb345b2ce5b31ae01f 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 185 1.1E-33 T 22-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS04330 d0bd819c77c822bb345b2ce5b31ae01f 194 PANTHER PTHR30173:SF1 1 191 7.3E-55 T 22-04-2016 TOLA_RS04330 d0bd819c77c822bb345b2ce5b31ae01f 194 SUPERFAMILY SSF88946 7 108 3.92E-30 T 22-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS12445 89225bd770e9339c1552821a432179ce 168 PANTHER PTHR30471 31 168 2.7E-65 T 22-04-2016 TOLA_RS12445 89225bd770e9339c1552821a432179ce 168 SUPERFAMILY SSF102712 57 134 5.75E-5 T 22-04-2016 TOLA_RS12445 89225bd770e9339c1552821a432179ce 168 Gene3D G3DSA:3.40.140.10 45 168 2.4E-47 T 22-04-2016 TOLA_RS12445 89225bd770e9339c1552821a432179ce 168 TIGRFAM TIGR00608 radc: DNA repair protein RadC 31 168 1.9E-41 T 22-04-2016 IPR001405 RadC protein TOLA_RS12445 89225bd770e9339c1552821a432179ce 168 Pfam PF04002 RadC-like JAB domain 48 166 1.2E-41 T 22-04-2016 IPR025657 RadC-like JAB domain TOLA_RS12445 89225bd770e9339c1552821a432179ce 168 PANTHER PTHR30471:SF5 31 168 2.7E-65 T 22-04-2016 TOLA_RS03515 73d4d891f3a8c3f8bdc12b67bc7769ac 519 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 2 501 41.807 T 22-04-2016 IPR003846 Uncharacterised protein family UPF0061 TOLA_RS03515 73d4d891f3a8c3f8bdc12b67bc7769ac 519 PANTHER PTHR32057 1 519 2.1E-207 T 22-04-2016 TOLA_RS03515 73d4d891f3a8c3f8bdc12b67bc7769ac 519 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 26 485 4.5E-135 T 22-04-2016 IPR003846 Uncharacterised protein family UPF0061 TOLA_RS07470 30ce26140f4b83795ed9867008c896c4 75 ProSitePatterns PS00194 Thioredoxin family active site. 19 37 - T 22-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 TOLA_RS07470 30ce26140f4b83795ed9867008c896c4 75 Gene3D G3DSA:3.40.30.10 3 70 1.1E-20 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS07470 30ce26140f4b83795ed9867008c896c4 75 SUPERFAMILY SSF52833 3 67 3.57E-21 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS07470 30ce26140f4b83795ed9867008c896c4 75 PIRSF PIRSF000077 1 75 3.5E-22 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TOLA_RS07470 30ce26140f4b83795ed9867008c896c4 75 PANTHER PTHR10438:SF266 4 66 4.3E-20 T 22-04-2016 TOLA_RS07470 30ce26140f4b83795ed9867008c896c4 75 Pfam PF00085 Thioredoxin 3 70 1.8E-19 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 TOLA_RS07470 30ce26140f4b83795ed9867008c896c4 75 PANTHER PTHR10438 4 66 4.3E-20 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TOLA_RS05805 1a589316601ae5e95ae34ae923ab4e20 115 PANTHER PTHR30041:SF3 3 115 3.5E-32 T 22-04-2016 TOLA_RS05805 1a589316601ae5e95ae34ae923ab4e20 115 PANTHER PTHR30041 3 115 3.5E-32 T 22-04-2016 TOLA_RS05805 1a589316601ae5e95ae34ae923ab4e20 115 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 113 5.2E-28 T 22-04-2016 IPR006504 Transcriptional regulator Spx/MgsR TOLA_RS05805 1a589316601ae5e95ae34ae923ab4e20 115 Pfam PF03960 ArsC family 10 111 1.3E-13 T 22-04-2016 IPR006660 Arsenate reductase-like TOLA_RS05805 1a589316601ae5e95ae34ae923ab4e20 115 SUPERFAMILY SSF52833 3 114 2.17E-32 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS05805 1a589316601ae5e95ae34ae923ab4e20 115 Gene3D G3DSA:3.40.30.10 3 114 8.8E-39 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS14435 5eab30ea16d0cec502418c06a5be0ae6 106 SUPERFAMILY SSF54913 2 104 2.37E-39 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta TOLA_RS14435 5eab30ea16d0cec502418c06a5be0ae6 106 Gene3D G3DSA:3.30.70.830 2 105 4.7E-43 T 22-04-2016 TOLA_RS14435 5eab30ea16d0cec502418c06a5be0ae6 106 PANTHER PTHR23419 5 104 5.9E-47 T 22-04-2016 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 TOLA_RS14435 5eab30ea16d0cec502418c06a5be0ae6 106 Pfam PF03091 CutA1 divalent ion tolerance protein 5 103 1.4E-38 T 22-04-2016 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 TOLA_RS00985 d8de24ccfce923a7593f068a3a01361a 151 Gene3D G3DSA:2.70.40.10 5 150 5.7E-56 T 22-04-2016 IPR029054 dUTPase-like TOLA_RS00985 d8de24ccfce923a7593f068a3a01361a 151 PANTHER PTHR11241 1 150 2.0E-55 T 22-04-2016 TOLA_RS00985 d8de24ccfce923a7593f068a3a01361a 151 SUPERFAMILY SSF51283 1 150 4.71E-57 T 22-04-2016 IPR029054 dUTPase-like TOLA_RS00985 d8de24ccfce923a7593f068a3a01361a 151 Pfam PF00692 dUTPase 16 149 3.0E-43 T 22-04-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 TOLA_RS00985 d8de24ccfce923a7593f068a3a01361a 151 TIGRFAM TIGR00576 dut: dUTP diphosphatase 9 150 5.3E-50 T 22-04-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|UniPathway: UPA00610 TOLA_RS00985 d8de24ccfce923a7593f068a3a01361a 151 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 150 34.493 T 22-04-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|UniPathway: UPA00610 TOLA_RS06075 626ba3cd644d96a98f8081433fbfd317 327 PANTHER PTHR13504:SF32 38 313 3.4E-42 T 22-04-2016 TOLA_RS06075 626ba3cd644d96a98f8081433fbfd317 327 SUPERFAMILY SSF140931 79 254 2.49E-42 T 22-04-2016 IPR003812 Fido domain TOLA_RS06075 626ba3cd644d96a98f8081433fbfd317 327 Gene3D G3DSA:1.10.3290.10 18 251 1.8E-58 T 22-04-2016 IPR003812 Fido domain TOLA_RS06075 626ba3cd644d96a98f8081433fbfd317 327 Pfam PF13412 Winged helix-turn-helix DNA-binding 272 310 1.1E-7 T 22-04-2016 TOLA_RS06075 626ba3cd644d96a98f8081433fbfd317 327 Pfam PF02661 Fic/DOC family 100 196 6.2E-23 T 22-04-2016 IPR003812 Fido domain TOLA_RS06075 626ba3cd644d96a98f8081433fbfd317 327 Gene3D G3DSA:1.10.10.10 272 310 7.7E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06075 626ba3cd644d96a98f8081433fbfd317 327 SUPERFAMILY SSF46785 270 325 3.0E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06075 626ba3cd644d96a98f8081433fbfd317 327 PANTHER PTHR13504 38 313 3.4E-42 T 22-04-2016 TOLA_RS00740 700d81da344f544d95d809d9e79d237e 276 Gene3D G3DSA:1.20.1540.10 95 265 1.2E-31 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TOLA_RS00740 700d81da344f544d95d809d9e79d237e 276 PANTHER PTHR22936:SF30 64 270 7.2E-46 T 22-04-2016 TOLA_RS00740 700d81da344f544d95d809d9e79d237e 276 TIGRFAM TIGR04239 rhombo_GlpG: rhomboid family protease GlpG 3 269 3.3E-101 T 22-04-2016 IPR023662 Rhomboid protease GlpG GO:0004252|GO:0006508|GO:0016021 TOLA_RS00740 700d81da344f544d95d809d9e79d237e 276 Pfam PF01694 Rhomboid family 129 266 1.3E-29 T 22-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TOLA_RS00740 700d81da344f544d95d809d9e79d237e 276 PANTHER PTHR22936 64 270 7.2E-46 T 22-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 TOLA_RS00740 700d81da344f544d95d809d9e79d237e 276 SUPERFAMILY SSF144091 95 266 6.67E-35 T 22-04-2016 TOLA_RS00740 700d81da344f544d95d809d9e79d237e 276 Pfam PF12122 Cytoplasmic N-terminal domain of rhomboid serine protease 1 72 5.4E-21 T 22-04-2016 IPR022732 Peptidase S54, GlpG peptidase, N-terminal GO:0004252|GO:0016021 TOLA_RS05570 25497494490774f949d81467302fe231 180 PANTHER PTHR38106:SF1 1 180 3.5E-56 T 22-04-2016 TOLA_RS05570 25497494490774f949d81467302fe231 180 Pfam PF04352 ProQ/FINO family 8 114 3.0E-39 T 22-04-2016 IPR016103 ProQ/FinO domain TOLA_RS05570 25497494490774f949d81467302fe231 180 PANTHER PTHR38106 1 180 3.5E-56 T 22-04-2016 TOLA_RS05570 25497494490774f949d81467302fe231 180 Gene3D G3DSA:1.10.1710.10 26 109 3.9E-34 T 22-04-2016 IPR016103 ProQ/FinO domain TOLA_RS05570 25497494490774f949d81467302fe231 180 Hamap MF_00749 RNA chaperone ProQ [proQ]. 2 179 24.997 T 22-04-2016 IPR023529 RNA chaperone ProQ GO:0003723|GO:0010608|GO:0033592|GO:0034057 TOLA_RS05570 25497494490774f949d81467302fe231 180 SUPERFAMILY SSF48657 3 109 7.06E-36 T 22-04-2016 IPR016103 ProQ/FinO domain TOLA_RS05570 25497494490774f949d81467302fe231 180 SMART SM00945 5 119 1.5E-54 T 22-04-2016 IPR016103 ProQ/FinO domain TOLA_RS02640 20744eeb839d817f079c596cf68591a0 192 Pfam PF01106 NifU-like domain 111 173 5.3E-19 T 22-04-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 TOLA_RS02640 20744eeb839d817f079c596cf68591a0 192 PANTHER PTHR10072:SF37 1 97 3.0E-79 T 22-04-2016 TOLA_RS02640 20744eeb839d817f079c596cf68591a0 192 PANTHER PTHR10072:SF37 147 189 3.0E-79 T 22-04-2016 TOLA_RS02640 20744eeb839d817f079c596cf68591a0 192 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 118 181 4.0E-23 T 22-04-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 TOLA_RS02640 20744eeb839d817f079c596cf68591a0 192 SUPERFAMILY SSF89360 1 97 5.69E-21 T 22-04-2016 IPR000361 FeS cluster biogenesis TOLA_RS02640 20744eeb839d817f079c596cf68591a0 192 PANTHER PTHR10072 1 97 3.0E-79 T 22-04-2016 TOLA_RS02640 20744eeb839d817f079c596cf68591a0 192 PANTHER PTHR10072 147 189 3.0E-79 T 22-04-2016 TOLA_RS02640 20744eeb839d817f079c596cf68591a0 192 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 98 6.5E-11 T 22-04-2016 IPR000361 FeS cluster biogenesis TOLA_RS02640 20744eeb839d817f079c596cf68591a0 192 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 1 192 45.046 T 22-04-2016 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 TOLA_RS02640 20744eeb839d817f079c596cf68591a0 192 SUPERFAMILY SSF117916 95 174 5.89E-22 T 22-04-2016 TOLA_RS02640 20744eeb839d817f079c596cf68591a0 192 Gene3D G3DSA:2.60.300.12 1 97 1.3E-17 T 22-04-2016 IPR000361 FeS cluster biogenesis TOLA_RS02640 20744eeb839d817f079c596cf68591a0 192 TIGRFAM TIGR03341 YhgI_GntY: IscR-regulated protein YhgI 2 192 5.3E-96 T 22-04-2016 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 TOLA_RS01600 823620193d39a71dadcea8465488520e 695 Pfam PF00665 Integrase core domain 266 405 3.5E-14 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 TOLA_RS01600 823620193d39a71dadcea8465488520e 695 SUPERFAMILY SSF53098 266 453 2.85E-11 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS01600 823620193d39a71dadcea8465488520e 695 Gene3D G3DSA:3.30.420.10 265 453 5.4E-14 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS04460 4d80a1b5d30480be02dea1dd1b916f75 355 PANTHER PTHR39342 1 353 4.8E-72 T 22-04-2016 TOLA_RS04460 4d80a1b5d30480be02dea1dd1b916f75 355 Pfam PF05128 Domain of unknown function (DUF697) 179 337 9.2E-48 T 22-04-2016 IPR021147 Protein of unknown function DUF697 TOLA_RS04460 4d80a1b5d30480be02dea1dd1b916f75 355 TIGRFAM TIGR01620 hyp_HI0043: TIGR01620 family protein 74 337 2.5E-70 T 22-04-2016 IPR006507 Uncharacterised protein family UPF0283 TOLA_RS04460 4d80a1b5d30480be02dea1dd1b916f75 355 PANTHER PTHR39342:SF1 1 353 4.8E-72 T 22-04-2016 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 Gene3D G3DSA:3.40.50.20 4 102 1.7E-18 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 Gene3D G3DSA:3.30.1490.20 132 195 3.0E-17 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 271 299 - T 22-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 PIRSF PIRSF039102 1 330 2.3E-78 T 22-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 329 32.863 T 22-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 327 8.8E-93 T 22-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 Pfam PF07478 D-ala D-ala ligase C-terminus 124 325 1.3E-54 T 22-04-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 Gene3D G3DSA:3.30.470.20 104 122 1.5E-40 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 Gene3D G3DSA:3.30.470.20 196 327 1.5E-40 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 82 93 - T 22-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 SUPERFAMILY SSF56059 115 325 2.12E-46 T 22-04-2016 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 Pfam PF01820 D-ala D-ala ligase N-terminus 6 105 2.9E-16 T 22-04-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 PANTHER PTHR23132:SF8 1 326 9.9E-110 T 22-04-2016 TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 SUPERFAMILY SSF52440 4 114 1.15E-23 T 22-04-2016 IPR016185 Pre-ATP-grasp domain TOLA_RS01235 7cff1cbe0b9704b3cbcd1befa0c4865d 330 PANTHER PTHR23132 1 326 9.9E-110 T 22-04-2016 TOLA_RS05625 96de7a1891ed060c7f5cc00be5e68de4 257 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 5 257 29.667 T 22-04-2016 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519|UniPathway: UPA00078 TOLA_RS05625 96de7a1891ed060c7f5cc00be5e68de4 257 SUPERFAMILY SSF53335 12 195 1.61E-34 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS05625 96de7a1891ed060c7f5cc00be5e68de4 257 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 13 256 1.5E-62 T 22-04-2016 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519|UniPathway: UPA00078 TOLA_RS05625 96de7a1891ed060c7f5cc00be5e68de4 257 PANTHER PTHR10108:SF855 14 179 1.8E-30 T 22-04-2016 TOLA_RS05625 96de7a1891ed060c7f5cc00be5e68de4 257 Pfam PF08241 Methyltransferase domain 48 139 1.6E-22 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 TOLA_RS05625 96de7a1891ed060c7f5cc00be5e68de4 257 PANTHER PTHR10108 14 179 1.8E-30 T 22-04-2016 TOLA_RS05625 96de7a1891ed060c7f5cc00be5e68de4 257 Gene3D G3DSA:3.40.50.150 12 237 2.0E-33 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07025 bf55c9f17a9cfda4a6ab09312e7aead6 355 Gene3D G3DSA:3.20.20.70 10 349 3.7E-146 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS07025 bf55c9f17a9cfda4a6ab09312e7aead6 355 SUPERFAMILY SSF51569 8 347 2.2E-133 T 22-04-2016 TOLA_RS07025 bf55c9f17a9cfda4a6ab09312e7aead6 355 Pfam PF00793 DAHP synthetase I family 42 340 2.6E-96 T 22-04-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 TOLA_RS07025 bf55c9f17a9cfda4a6ab09312e7aead6 355 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 9 348 8.3E-155 T 22-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 TOLA_RS07025 bf55c9f17a9cfda4a6ab09312e7aead6 355 PANTHER PTHR21225 1 349 1.3E-211 T 22-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 TOLA_RS07025 bf55c9f17a9cfda4a6ab09312e7aead6 355 PIRSF PIRSF001361 1 354 5.2E-158 T 22-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 TOLA_RS04210 0ff6cacc6bebcc2cdaa0ef2251948ed3 362 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 360 5.6E-164 T 22-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 TOLA_RS04210 0ff6cacc6bebcc2cdaa0ef2251948ed3 362 Gene3D G3DSA:3.30.160.20 217 291 1.3E-36 T 22-04-2016 IPR014720 Double-stranded RNA-binding domain TOLA_RS04210 0ff6cacc6bebcc2cdaa0ef2251948ed3 362 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TOLA_RS04210 0ff6cacc6bebcc2cdaa0ef2251948ed3 362 PANTHER PTHR11075 1 358 1.6E-174 T 22-04-2016 TOLA_RS04210 0ff6cacc6bebcc2cdaa0ef2251948ed3 362 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 359 40.117 T 22-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 TOLA_RS04210 0ff6cacc6bebcc2cdaa0ef2251948ed3 362 PANTHER PTHR11075:SF9 1 358 1.6E-174 T 22-04-2016 TOLA_RS04210 0ff6cacc6bebcc2cdaa0ef2251948ed3 362 Pfam PF00472 RF-1 domain 218 323 7.2E-41 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TOLA_RS04210 0ff6cacc6bebcc2cdaa0ef2251948ed3 362 SMART SM00937 67 180 1.3E-63 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 TOLA_RS04210 0ff6cacc6bebcc2cdaa0ef2251948ed3 362 SUPERFAMILY SSF75620 12 355 9.55E-136 T 22-04-2016 TOLA_RS04210 0ff6cacc6bebcc2cdaa0ef2251948ed3 362 Pfam PF03462 PCRF domain 13 205 4.2E-74 T 22-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 TOLA_RS04210 0ff6cacc6bebcc2cdaa0ef2251948ed3 362 Gene3D G3DSA:1.20.58.410 7 95 1.0E-22 T 22-04-2016 TOLA_RS10385 b8e607e576525b69f403f8ef75733983 565 Pfam PF11846 Virulence factor membrane-bound polymerase, C-terminal 372 551 1.0E-33 T 22-04-2016 IPR021797 Virulence factor membrane-bound polymerase, C-terminal TOLA_RS10385 b8e607e576525b69f403f8ef75733983 565 Pfam PF04932 O-Antigen ligase 207 350 3.4E-8 T 22-04-2016 IPR007016 O-antigen ligase-related TOLA_RS09885 9f766287dca80706ba890ed66e611bbe 346 Gene3D G3DSA:3.40.50.2300 175 331 4.0E-50 T 22-04-2016 TOLA_RS09885 9f766287dca80706ba890ed66e611bbe 346 SUPERFAMILY SSF53822 54 331 6.42E-70 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS09885 9f766287dca80706ba890ed66e611bbe 346 PANTHER PTHR32196 54 344 9.4E-50 T 22-04-2016 TOLA_RS09885 9f766287dca80706ba890ed66e611bbe 346 Gene3D G3DSA:3.40.50.2300 55 174 6.1E-27 T 22-04-2016 TOLA_RS09885 9f766287dca80706ba890ed66e611bbe 346 Pfam PF13407 Periplasmic binding protein domain 58 311 2.6E-55 T 22-04-2016 IPR025997 Periplasmic binding protein TOLA_RS09885 9f766287dca80706ba890ed66e611bbe 346 PANTHER PTHR32196:SF9 54 344 9.4E-50 T 22-04-2016 TOLA_RS09435 ce84538367877a5541755799c521bcd2 310 PANTHER PTHR18866 145 262 5.2E-35 T 22-04-2016 TOLA_RS09435 ce84538367877a5541755799c521bcd2 310 SUPERFAMILY SSF50891 173 288 1.82E-13 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS09435 ce84538367877a5541755799c521bcd2 310 PANTHER PTHR18866:SF74 145 262 5.2E-35 T 22-04-2016 TOLA_RS09435 ce84538367877a5541755799c521bcd2 310 Gene3D G3DSA:2.40.100.10 174 295 7.9E-10 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS09435 ce84538367877a5541755799c521bcd2 310 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 2 306 1.8E-102 T 22-04-2016 IPR003778 Carboxyltransferase domain, subdomain A and B TOLA_RS09435 ce84538367877a5541755799c521bcd2 310 SMART SM00797 23 298 5.2E-127 T 22-04-2016 IPR003778 Carboxyltransferase domain, subdomain A and B TOLA_RS09435 ce84538367877a5541755799c521bcd2 310 Pfam PF02626 Allophanate hydrolase subunit 2 25 281 2.6E-88 T 22-04-2016 IPR003778 Carboxyltransferase domain, subdomain A and B TOLA_RS06575 e223dbe33e15ec794f9f04a75528c6da 91 Pfam PF13417 Glutathione S-transferase, N-terminal domain 14 89 1.1E-10 T 22-04-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TOLA_RS06575 e223dbe33e15ec794f9f04a75528c6da 91 SUPERFAMILY SSF52833 12 89 3.43E-15 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS06575 e223dbe33e15ec794f9f04a75528c6da 91 Gene3D G3DSA:3.40.30.10 20 89 6.6E-18 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS01455 6c83304c12ba4fa0ddc6762a8af3a1d9 197 SUPERFAMILY SSF159594 26 186 9.15E-25 T 22-04-2016 TOLA_RS01455 6c83304c12ba4fa0ddc6762a8af3a1d9 197 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 33 183 6.6E-36 T 22-04-2016 IPR005586 ABC-type transport auxiliary lipoprotein component TOLA_RS01455 6c83304c12ba4fa0ddc6762a8af3a1d9 197 Gene3D G3DSA:3.40.50.10610 16 188 7.6E-14 T 22-04-2016 IPR005586 ABC-type transport auxiliary lipoprotein component TOLA_RS06715 1bf8efd3096c51ec93a2f4eb1f97a23e 182 SUPERFAMILY SSF52980 2 177 9.92E-70 T 22-04-2016 IPR011335 Restriction endonuclease type II-like TOLA_RS06715 1bf8efd3096c51ec93a2f4eb1f97a23e 182 PANTHER PTHR38784:SF1 1 182 1.5E-85 T 22-04-2016 TOLA_RS06715 1bf8efd3096c51ec93a2f4eb1f97a23e 182 PANTHER PTHR38784 1 182 1.5E-85 T 22-04-2016 TOLA_RS06715 1bf8efd3096c51ec93a2f4eb1f97a23e 182 Gene3D G3DSA:3.10.640.10 1 177 5.6E-77 T 22-04-2016 TOLA_RS06715 1bf8efd3096c51ec93a2f4eb1f97a23e 182 SMART SM01322 1 176 1.2E-118 T 22-04-2016 IPR009822 YaeQ TOLA_RS06715 1bf8efd3096c51ec93a2f4eb1f97a23e 182 Pfam PF07152 YaeQ protein 1 172 7.1E-74 T 22-04-2016 IPR009822 YaeQ TOLA_RS06715 1bf8efd3096c51ec93a2f4eb1f97a23e 182 PIRSF PIRSF011484 1 179 1.9E-66 T 22-04-2016 IPR009822 YaeQ TOLA_RS14255 9d1e1afb3beefd6b9defae8556cfe973 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 48 1.8E-16 T 22-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS14255 9d1e1afb3beefd6b9defae8556cfe973 121 Gene3D G3DSA:3.30.1390.10 51 121 1.7E-32 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TOLA_RS14255 9d1e1afb3beefd6b9defae8556cfe973 121 Gene3D G3DSA:1.20.5.710 2 50 4.8E-22 T 22-04-2016 TOLA_RS14255 9d1e1afb3beefd6b9defae8556cfe973 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 121 1.3E-44 T 22-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS14255 9d1e1afb3beefd6b9defae8556cfe973 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 1.1E-29 T 22-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 TOLA_RS14255 9d1e1afb3beefd6b9defae8556cfe973 121 SUPERFAMILY SSF54736 50 121 3.14E-24 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TOLA_RS14255 9d1e1afb3beefd6b9defae8556cfe973 121 SUPERFAMILY SSF48300 3 57 4.05E-16 T 22-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS14255 9d1e1afb3beefd6b9defae8556cfe973 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 121 9.0E-15 T 22-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 TOLA_RS14255 9d1e1afb3beefd6b9defae8556cfe973 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 121 25.078 T 22-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS14005 f0ba0c20fc602b0bc8762cfac25e760a 227 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 3 224 30.936 T 22-04-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS14005 f0ba0c20fc602b0bc8762cfac25e760a 227 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 223 2.7E-78 T 22-04-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS14005 f0ba0c20fc602b0bc8762cfac25e760a 227 Gene3D G3DSA:3.90.550.10 2 225 1.9E-76 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS14005 f0ba0c20fc602b0bc8762cfac25e760a 227 PANTHER PTHR32125:SF4 1 227 5.3E-79 T 22-04-2016 TOLA_RS14005 f0ba0c20fc602b0bc8762cfac25e760a 227 SUPERFAMILY SSF53448 4 222 6.93E-62 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS14005 f0ba0c20fc602b0bc8762cfac25e760a 227 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 6 221 1.2E-75 T 22-04-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS14005 f0ba0c20fc602b0bc8762cfac25e760a 227 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 97 104 - T 22-04-2016 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS14005 f0ba0c20fc602b0bc8762cfac25e760a 227 PANTHER PTHR32125 1 227 5.3E-79 T 22-04-2016 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 690 4.7E-179 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 PANTHER PTHR11649:SF37 661 728 1.1E-236 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 PANTHER PTHR11649:SF37 260 608 1.1E-236 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 PANTHER PTHR11649:SF37 4 147 1.1E-236 T 22-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 Gene3D G3DSA:3.40.50.300 5 165 2.8E-33 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 PANTHER PTHR11649 661 728 1.1E-236 T 22-04-2016 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 PANTHER PTHR11649 260 608 1.1E-236 T 22-04-2016 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 PANTHER PTHR11649 4 147 1.1E-236 T 22-04-2016 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 155 7.7E-12 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 53 68 4.8E-5 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.8E-5 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 SUPERFAMILY SSF52540 5 162 2.17E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 Pfam PF02421 Ferrous iron transport protein B 4 154 1.0E-59 T 22-04-2016 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 Pfam PF07664 Ferrous iron transport protein B C terminus 453 505 2.5E-17 T 22-04-2016 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 Pfam PF07670 Nucleoside recognition 350 440 9.0E-12 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 TOLA_RS10900 816b07d2ac4d0114b93d8e79b9a808fc 759 Pfam PF07670 Nucleoside recognition 511 693 2.1E-33 T 22-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 TOLA_RS04595 2a7afd46c312f2c005a91d6b32a1d33a 180 Pfam PF01814 Hemerythrin HHE cation binding domain 2 136 3.4E-13 T 22-04-2016 IPR012312 Haemerythrin-like TOLA_RS04595 2a7afd46c312f2c005a91d6b32a1d33a 180 Gene3D G3DSA:1.20.120.520 2 155 8.7E-21 T 22-04-2016 TOLA_RS11390 27244ddcf6d6efc255d1e76060d636d1 324 PANTHER PTHR13767:SF2 2 310 5.5E-130 T 22-04-2016 TOLA_RS11390 27244ddcf6d6efc255d1e76060d636d1 324 SUPERFAMILY SSF88697 252 311 1.74E-13 T 22-04-2016 IPR015947 PUA-like domain TOLA_RS11390 27244ddcf6d6efc255d1e76060d636d1 324 Gene3D G3DSA:2.30.130.10 252 311 2.8E-26 T 22-04-2016 IPR015947 PUA-like domain TOLA_RS11390 27244ddcf6d6efc255d1e76060d636d1 324 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 182 249 2.0E-22 T 22-04-2016 IPR032819 tRNA pseudouridylate synthase B, C-terminal TOLA_RS11390 27244ddcf6d6efc255d1e76060d636d1 324 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 253 310 3.7E-19 T 22-04-2016 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS11390 27244ddcf6d6efc255d1e76060d636d1 324 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 12 310 19.089 T 22-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS11390 27244ddcf6d6efc255d1e76060d636d1 324 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 34 181 2.8E-59 T 22-04-2016 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 TOLA_RS11390 27244ddcf6d6efc255d1e76060d636d1 324 PANTHER PTHR13767 2 310 5.5E-130 T 22-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS11390 27244ddcf6d6efc255d1e76060d636d1 324 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 13 220 3.0E-84 T 22-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS11390 27244ddcf6d6efc255d1e76060d636d1 324 SUPERFAMILY SSF55120 12 249 6.62E-84 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS08765 97d5c87ae5e66d9fe03086d08ccd624a 106 Gene3D G3DSA:4.10.520.10 2 93 7.4E-35 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 TOLA_RS08765 97d5c87ae5e66d9fe03086d08ccd624a 106 SMART SM00411 3 92 4.2E-40 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS08765 97d5c87ae5e66d9fe03086d08ccd624a 106 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 1 97 30.025 T 22-04-2016 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355|GO:0006417 TOLA_RS08765 97d5c87ae5e66d9fe03086d08ccd624a 106 PANTHER PTHR33175 2 99 5.6E-53 T 22-04-2016 TOLA_RS08765 97d5c87ae5e66d9fe03086d08ccd624a 106 SUPERFAMILY SSF47729 3 93 8.1E-31 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 TOLA_RS08765 97d5c87ae5e66d9fe03086d08ccd624a 106 PANTHER PTHR33175:SF2 2 99 5.6E-53 T 22-04-2016 TOLA_RS08765 97d5c87ae5e66d9fe03086d08ccd624a 106 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 48 67 - T 22-04-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 TOLA_RS08765 97d5c87ae5e66d9fe03086d08ccd624a 106 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 6.8E-17 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS08765 97d5c87ae5e66d9fe03086d08ccd624a 106 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 6.8E-17 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS08765 97d5c87ae5e66d9fe03086d08ccd624a 106 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 6.8E-17 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS08765 97d5c87ae5e66d9fe03086d08ccd624a 106 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 2 95 3.8E-49 T 22-04-2016 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355|GO:0006417 TOLA_RS08765 97d5c87ae5e66d9fe03086d08ccd624a 106 Pfam PF00216 Bacterial DNA-binding protein 3 91 3.4E-31 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS14910 b46c3cd762ac643452e4d93c350bdf6b 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 56 - T 22-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TOLA_RS14910 b46c3cd762ac643452e4d93c350bdf6b 192 SUPERFAMILY SSF46689 8 80 1.4E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS14910 b46c3cd762ac643452e4d93c350bdf6b 192 Gene3D G3DSA:1.10.357.10 8 190 4.0E-29 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 TOLA_RS14910 b46c3cd762ac643452e4d93c350bdf6b 192 Pfam PF16295 Tetracycline repressor, C-terminal all-alpha domain 92 189 2.6E-8 T 22-04-2016 IPR032551 HTH-type transcriptional repressor, C-terminal TOLA_RS14910 b46c3cd762ac643452e4d93c350bdf6b 192 PANTHER PTHR30055 4 189 6.6E-35 T 22-04-2016 TOLA_RS14910 b46c3cd762ac643452e4d93c350bdf6b 192 PANTHER PTHR30055:SF82 4 189 6.6E-35 T 22-04-2016 TOLA_RS14910 b46c3cd762ac643452e4d93c350bdf6b 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 4.8E-10 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS14910 b46c3cd762ac643452e4d93c350bdf6b 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 4.8E-10 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS14910 b46c3cd762ac643452e4d93c350bdf6b 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 6.4E-17 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS15815 fa44503000ffa8ea9e478591a14b9928 173 PANTHER PTHR35812:SF2 31 173 1.0E-11 T 22-04-2016 TOLA_RS15815 fa44503000ffa8ea9e478591a14b9928 173 Pfam PF07603 Protein of unknown function (DUF1566) 44 170 7.6E-32 T 22-04-2016 IPR011460 Protein of unknown function DUF1566 TOLA_RS15815 fa44503000ffa8ea9e478591a14b9928 173 PANTHER PTHR35812 31 173 1.0E-11 T 22-04-2016 TOLA_RS11785 a229e5ef5cb26363ae59d6aad1122820 247 SUPERFAMILY SSF55729 77 235 2.47E-23 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS11785 a229e5ef5cb26363ae59d6aad1122820 247 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 1 233 39.376 T 22-04-2016 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic TOLA_RS11785 a229e5ef5cb26363ae59d6aad1122820 247 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 14 84 3.7E-17 T 22-04-2016 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 TOLA_RS11785 a229e5ef5cb26363ae59d6aad1122820 247 PANTHER PTHR21367:SF0 7 230 5.6E-70 T 22-04-2016 TOLA_RS11785 a229e5ef5cb26363ae59d6aad1122820 247 PIRSF PIRSF037208 1 243 2.2E-88 T 22-04-2016 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic TOLA_RS11785 a229e5ef5cb26363ae59d6aad1122820 247 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 104 224 9.5E-37 T 22-04-2016 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 TOLA_RS11785 a229e5ef5cb26363ae59d6aad1122820 247 PANTHER PTHR21367 7 230 5.6E-70 T 22-04-2016 IPR030700 Arginine-tRNA-protein transferase TOLA_RS11810 9015ef38f91e0e47c5d71bf0f7b63548 417 SUPERFAMILY SSF53659 4 416 2.5E-145 T 22-04-2016 TOLA_RS11810 9015ef38f91e0e47c5d71bf0f7b63548 417 PANTHER PTHR11835 189 256 4.9E-240 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 TOLA_RS11810 9015ef38f91e0e47c5d71bf0f7b63548 417 PANTHER PTHR11835 1 165 4.9E-240 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 TOLA_RS11810 9015ef38f91e0e47c5d71bf0f7b63548 417 PANTHER PTHR11835 276 417 4.9E-240 T 22-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 TOLA_RS11810 9015ef38f91e0e47c5d71bf0f7b63548 417 SMART SM01329 29 413 1.6E-174 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 TOLA_RS11810 9015ef38f91e0e47c5d71bf0f7b63548 417 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 30 412 1.8E-114 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 TOLA_RS11810 9015ef38f91e0e47c5d71bf0f7b63548 417 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 304 323 - T 22-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 TOLA_RS11810 9015ef38f91e0e47c5d71bf0f7b63548 417 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 1 417 4.4E-231 T 22-04-2016 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 TOLA_RS11810 9015ef38f91e0e47c5d71bf0f7b63548 417 PANTHER PTHR11835:SF52 189 256 4.9E-240 T 22-04-2016 TOLA_RS11810 9015ef38f91e0e47c5d71bf0f7b63548 417 PANTHER PTHR11835:SF52 1 165 4.9E-240 T 22-04-2016 TOLA_RS11810 9015ef38f91e0e47c5d71bf0f7b63548 417 PANTHER PTHR11835:SF52 276 417 4.9E-240 T 22-04-2016 TOLA_RS11810 9015ef38f91e0e47c5d71bf0f7b63548 417 Gene3D G3DSA:3.40.718.10 12 417 2.1E-163 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 TOLA_RS03355 1207983297a66fafdd541d9eb22f9b71 482 TIGRFAM TIGR01282 nifD: nitrogenase molybdenum-iron protein alpha chain 12 478 9.9E-262 T 22-04-2016 IPR005972 Nitrogenase molybdenum-iron protein alpha chain GO:0009399|GO:0016163|GO:0016612|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 TOLA_RS03355 1207983297a66fafdd541d9eb22f9b71 482 Pfam PF00148 Nitrogenase component 1 type Oxidoreductase 62 466 3.5E-110 T 22-04-2016 IPR000510 Nitrogenase/oxidoreductase, component 1 GO:0016491|GO:0055114 TOLA_RS03355 1207983297a66fafdd541d9eb22f9b71 482 Gene3D G3DSA:3.40.50.1980 311 353 6.2E-4 T 22-04-2016 TOLA_RS03355 1207983297a66fafdd541d9eb22f9b71 482 SUPERFAMILY SSF53807 7 479 5.29E-162 T 22-04-2016 TOLA_RS03355 1207983297a66fafdd541d9eb22f9b71 482 PANTHER PTHR33712:SF4 19 479 2.3E-294 T 22-04-2016 TOLA_RS03355 1207983297a66fafdd541d9eb22f9b71 482 Gene3D G3DSA:3.40.50.1980 214 310 1.4E-51 T 22-04-2016 TOLA_RS03355 1207983297a66fafdd541d9eb22f9b71 482 Gene3D G3DSA:3.40.50.1980 354 481 8.5E-63 T 22-04-2016 TOLA_RS03355 1207983297a66fafdd541d9eb22f9b71 482 TIGRFAM TIGR01862 N2-ase-Ialpha: nitrogenase component I, alpha chain 27 472 1.5E-195 T 22-04-2016 IPR010143 Nitrogenase component 1, alpha chain GO:0009399|GO:0016163|GO:0051536|GO:0055114 KEGG: 00625+1.18.6.1|KEGG: 00910+1.18.6.1 TOLA_RS03355 1207983297a66fafdd541d9eb22f9b71 482 Gene3D G3DSA:3.40.50.1980 11 166 4.5E-68 T 22-04-2016 TOLA_RS03355 1207983297a66fafdd541d9eb22f9b71 482 ProSitePatterns PS00090 Nitrogenases component 1 alpha and beta subunits signature 2. 152 166 - T 22-04-2016 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TOLA_RS03355 1207983297a66fafdd541d9eb22f9b71 482 ProSitePatterns PS00699 Nitrogenases component 1 alpha and beta subunits signature 1. 81 88 - T 22-04-2016 IPR000318 Nitrogenase component 1, conserved site GO:0009399|GO:0016163 TOLA_RS03355 1207983297a66fafdd541d9eb22f9b71 482 PANTHER PTHR33712 19 479 2.3E-294 T 22-04-2016 TOLA_RS12570 385384614e66f4064cb4498710aa6de0 473 SUPERFAMILY SSF54637 19 150 9.44E-19 T 22-04-2016 IPR029069 HotDog domain TOLA_RS12570 385384614e66f4064cb4498710aa6de0 473 Gene3D G3DSA:3.40.50.10750 282 438 4.4E-49 T 22-04-2016 TOLA_RS12570 385384614e66f4064cb4498710aa6de0 473 PANTHER PTHR23406 305 442 5.9E-14 T 22-04-2016 TOLA_RS12570 385384614e66f4064cb4498710aa6de0 473 PANTHER PTHR23406:SF1 305 442 5.9E-14 T 22-04-2016 TOLA_RS12570 385384614e66f4064cb4498710aa6de0 473 SUPERFAMILY SSF53659 175 467 4.11E-68 T 22-04-2016 TOLA_RS12570 385384614e66f4064cb4498710aa6de0 473 Gene3D G3DSA:3.10.129.10 22 147 3.7E-23 T 22-04-2016 IPR029069 HotDog domain TOLA_RS12570 385384614e66f4064cb4498710aa6de0 473 Pfam PF01515 Phosphate acetyl/butaryl transferase 247 461 3.6E-42 T 22-04-2016 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 TOLA_RS13135 3251bd7c303d246759422073d4ef88ad 444 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 111 136 - T 22-04-2016 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TOLA_RS13135 3251bd7c303d246759422073d4ef88ad 444 PANTHER PTHR13794:SF47 172 429 5.9E-245 T 22-04-2016 TOLA_RS13135 3251bd7c303d246759422073d4ef88ad 444 PANTHER PTHR13794:SF47 6 151 5.9E-245 T 22-04-2016 TOLA_RS13135 3251bd7c303d246759422073d4ef88ad 444 SUPERFAMILY SSF51604 138 414 2.83E-85 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS13135 3251bd7c303d246759422073d4ef88ad 444 Gene3D G3DSA:3.20.20.120 124 396 2.5E-103 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS13135 3251bd7c303d246759422073d4ef88ad 444 SMART SM00922 184 284 2.9E-16 T 22-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TOLA_RS13135 3251bd7c303d246759422073d4ef88ad 444 PANTHER PTHR13794 172 429 5.9E-245 T 22-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 TOLA_RS13135 3251bd7c303d246759422073d4ef88ad 444 PANTHER PTHR13794 6 151 5.9E-245 T 22-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 TOLA_RS13135 3251bd7c303d246759422073d4ef88ad 444 SUPERFAMILY SSF54826 6 136 7.24E-30 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TOLA_RS13135 3251bd7c303d246759422073d4ef88ad 444 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 30 136 9.1E-7 T 22-04-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TOLA_RS13135 3251bd7c303d246759422073d4ef88ad 444 Gene3D G3DSA:3.30.390.10 8 123 8.5E-15 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TOLA_RS13135 3251bd7c303d246759422073d4ef88ad 444 Pfam PF13378 Enolase C-terminal domain-like 189 403 2.2E-39 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS15630 abd3d7b4009ec0e8b221083825c7ca14 160 PANTHER PTHR34986 2 155 4.1E-41 T 22-04-2016 TOLA_RS15630 abd3d7b4009ec0e8b221083825c7ca14 160 SUPERFAMILY SSF51197 1 153 2.42E-34 T 22-04-2016 TOLA_RS15630 abd3d7b4009ec0e8b221083825c7ca14 160 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 1 150 4.4E-37 T 22-04-2016 IPR004375 YhcH/YjgK/YiaL family TOLA_RS15630 abd3d7b4009ec0e8b221083825c7ca14 160 Gene3D G3DSA:2.60.120.370 1 151 9.0E-40 T 22-04-2016 IPR004375 YhcH/YjgK/YiaL family TOLA_RS15630 abd3d7b4009ec0e8b221083825c7ca14 160 PANTHER PTHR34986:SF1 2 155 4.1E-41 T 22-04-2016 TOLA_RS15630 abd3d7b4009ec0e8b221083825c7ca14 160 Pfam PF04074 Domain of unknown function (DUF386) 1 149 9.1E-36 T 22-04-2016 IPR004375 YhcH/YjgK/YiaL family TOLA_RS01685 b4b6b414ee6a02511343a42e144ad15d 197 PANTHER PTHR10108:SF838 1 167 7.7E-47 T 22-04-2016 TOLA_RS01685 b4b6b414ee6a02511343a42e144ad15d 197 Pfam PF13649 Methyltransferase domain 34 126 3.7E-11 T 22-04-2016 TOLA_RS01685 b4b6b414ee6a02511343a42e144ad15d 197 SUPERFAMILY SSF53335 2 175 4.22E-30 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS01685 b4b6b414ee6a02511343a42e144ad15d 197 PANTHER PTHR10108 1 167 7.7E-47 T 22-04-2016 TOLA_RS01685 b4b6b414ee6a02511343a42e144ad15d 197 Gene3D G3DSA:3.40.50.150 2 173 1.6E-25 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS01050 669b554252c535510e848a1726199da9 164 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 7 159 3.1E-51 T 22-04-2016 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 TOLA_RS01050 669b554252c535510e848a1726199da9 164 PANTHER PTHR35850:SF2 1 161 2.1E-74 T 22-04-2016 TOLA_RS01050 669b554252c535510e848a1726199da9 164 PIRSF PIRSF028301 1 164 6.1E-53 T 22-04-2016 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 TOLA_RS01050 669b554252c535510e848a1726199da9 164 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 4 160 2.7E-50 T 22-04-2016 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 TOLA_RS01050 669b554252c535510e848a1726199da9 164 PANTHER PTHR35850 1 161 2.1E-74 T 22-04-2016 TOLA_RS13710 c063969573fa800cbacca086ef898d42 132 PANTHER PTHR10173 8 127 5.3E-63 T 22-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 TOLA_RS13710 c063969573fa800cbacca086ef898d42 132 PANTHER PTHR10173:SF18 8 127 5.3E-63 T 22-04-2016 TOLA_RS13710 c063969573fa800cbacca086ef898d42 132 Pfam PF01641 SelR domain 8 125 2.6E-54 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 TOLA_RS13710 c063969573fa800cbacca086ef898d42 132 SUPERFAMILY SSF51316 7 129 1.53E-59 T 22-04-2016 IPR011057 Mss4-like TOLA_RS13710 c063969573fa800cbacca086ef898d42 132 Gene3D G3DSA:2.170.150.20 4 129 5.7E-62 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 TOLA_RS13710 c063969573fa800cbacca086ef898d42 132 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 129 7.8E-55 T 22-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 TOLA_RS15400 6160835336d5562e586069b17e80c31d 246 Hamap MF_01523 Ribosomal RNA small subunit methyltransferase J [rsmJ]. 1 245 39.847 T 22-04-2016 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 TOLA_RS15400 6160835336d5562e586069b17e80c31d 246 PANTHER PTHR36112:SF1 16 245 1.8E-126 T 22-04-2016 TOLA_RS15400 6160835336d5562e586069b17e80c31d 246 PANTHER PTHR36112 16 245 1.8E-126 T 22-04-2016 TOLA_RS15400 6160835336d5562e586069b17e80c31d 246 Gene3D G3DSA:3.40.1630.10 1 53 1.8E-16 T 22-04-2016 TOLA_RS15400 6160835336d5562e586069b17e80c31d 246 Gene3D G3DSA:3.40.50.150 54 244 1.1E-78 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS15400 6160835336d5562e586069b17e80c31d 246 SUPERFAMILY SSF53335 3 245 3.73E-77 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS15400 6160835336d5562e586069b17e80c31d 246 Pfam PF04445 Putative SAM-dependent methyltransferase 20 243 8.9E-106 T 22-04-2016 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 TOLA_RS07750 51e49d4ef34b9c5ff4c769248a96c47c 981 SMART SM00304 371 424 0.0075 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS07750 51e49d4ef34b9c5ff4c769248a96c47c 981 Pfam PF00672 HAMP domain 353 420 1.9E-8 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS07750 51e49d4ef34b9c5ff4c769248a96c47c 981 Gene3D G3DSA:3.30.450.20 168 226 7.5E-17 T 22-04-2016 TOLA_RS07750 51e49d4ef34b9c5ff4c769248a96c47c 981 Gene3D G3DSA:3.30.450.20 84 121 7.5E-17 T 22-04-2016 TOLA_RS07750 51e49d4ef34b9c5ff4c769248a96c47c 981 SUPERFAMILY SSF109604 600 744 5.97E-8 T 22-04-2016 TOLA_RS07750 51e49d4ef34b9c5ff4c769248a96c47c 981 Pfam PF13487 HD domain 832 897 1.7E-24 T 22-04-2016 TOLA_RS07750 51e49d4ef34b9c5ff4c769248a96c47c 981 SUPERFAMILY SSF109604 831 940 1.38E-8 T 22-04-2016 TOLA_RS07750 51e49d4ef34b9c5ff4c769248a96c47c 981 SUPERFAMILY SSF55781 436 588 2.08E-7 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS07750 51e49d4ef34b9c5ff4c769248a96c47c 981 SMART SM00471 603 915 0.0021 T 22-04-2016 IPR003607 HD/PDEase domain TOLA_RS07750 51e49d4ef34b9c5ff4c769248a96c47c 981 Gene3D G3DSA:1.10.3210.10 592 673 1.4E-6 T 22-04-2016 IPR006674 HD domain TOLA_RS07750 51e49d4ef34b9c5ff4c769248a96c47c 981 Gene3D G3DSA:3.30.450.40 425 589 1.3E-6 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS11200 f9110bcb05f4f0825309cf1ee8b8d7c9 314 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 14 301 3.0E-69 T 22-04-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 TOLA_RS11200 f9110bcb05f4f0825309cf1ee8b8d7c9 314 Hamap MF_01944 Lipid A biosynthesis myristoyltransferase [lpxM]. 1 307 48.038 T 22-04-2016 IPR011921 Lipid A biosynthesis myristoyltransferase GO:0009103|GO:0009276|GO:0016021|GO:0016747 KEGG: 00540+2.3.1.243|KEGG: 00600+2.3.1.24|UniPathway: UPA00030|UniPathway: UPA00360 TOLA_RS11200 f9110bcb05f4f0825309cf1ee8b8d7c9 314 PIRSF PIRSF026649 8 311 2.8E-90 T 22-04-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 TOLA_RS11200 f9110bcb05f4f0825309cf1ee8b8d7c9 314 TIGRFAM TIGR02208 lipid_A_msbB: lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 9 311 3.6E-102 T 22-04-2016 IPR011921 Lipid A biosynthesis myristoyltransferase GO:0009103|GO:0009276|GO:0016021|GO:0016747 KEGG: 00540+2.3.1.243|KEGG: 00600+2.3.1.24|UniPathway: UPA00030|UniPathway: UPA00360 TOLA_RS11200 f9110bcb05f4f0825309cf1ee8b8d7c9 314 PANTHER PTHR30606:SF4 6 312 1.0E-103 T 22-04-2016 TOLA_RS11200 f9110bcb05f4f0825309cf1ee8b8d7c9 314 PANTHER PTHR30606 6 312 1.0E-103 T 22-04-2016 TOLA_RS01315 622e66f9e726f85ebf0c7d4ef3168ea4 151 Gene3D G3DSA:1.10.10.10 4 149 2.3E-43 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01315 622e66f9e726f85ebf0c7d4ef3168ea4 151 PANTHER PTHR33164 3 147 4.8E-55 T 22-04-2016 TOLA_RS01315 622e66f9e726f85ebf0c7d4ef3168ea4 151 SUPERFAMILY SSF46785 3 146 3.42E-35 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01315 622e66f9e726f85ebf0c7d4ef3168ea4 151 Pfam PF01047 MarR family 40 96 7.8E-18 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS01315 622e66f9e726f85ebf0c7d4ef3168ea4 151 PANTHER PTHR33164:SF5 3 147 4.8E-55 T 22-04-2016 TOLA_RS01315 622e66f9e726f85ebf0c7d4ef3168ea4 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 4.3E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS01315 622e66f9e726f85ebf0c7d4ef3168ea4 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 4.3E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS01315 622e66f9e726f85ebf0c7d4ef3168ea4 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 4.3E-8 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS01315 622e66f9e726f85ebf0c7d4ef3168ea4 151 SMART SM00347 33 131 9.0E-24 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 Gene3D G3DSA:3.40.50.620 4 222 1.7E-152 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 Gene3D G3DSA:3.40.50.620 617 646 1.7E-152 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 Gene3D G3DSA:3.40.50.620 425 573 1.7E-152 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 857 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 SUPERFAMILY SSF50677 226 415 8.27E-59 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PANTHER PTHR11946 240 571 0.0 T 22-04-2016 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PANTHER PTHR11946 614 857 0.0 T 22-04-2016 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PANTHER PTHR11946 1 206 0.0 T 22-04-2016 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 SUPERFAMILY SSF52374 4 226 9.05E-142 T 22-04-2016 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 SUPERFAMILY SSF52374 416 666 9.05E-142 T 22-04-2016 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 Gene3D G3DSA:3.90.740.10 223 424 5.4E-60 T 22-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 SUPERFAMILY SSF47323 662 857 1.81E-32 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PANTHER PTHR11946:SF7 240 571 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PANTHER PTHR11946:SF7 614 857 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PANTHER PTHR11946:SF7 1 206 0.0 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 Gene3D G3DSA:1.10.730.10 647 793 4.0E-43 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 4.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 4.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 4.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 4.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 4.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 4.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 4.9E-52 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 Pfam PF08264 Anticodon-binding domain of tRNA 698 819 9.1E-15 T 22-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 404 2.7E-78 T 22-04-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 171 2.3E-28 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 617 650 9.6E-7 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 418 572 1.0E-7 T 22-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS14470 189ba4d798e84ca29747d9f95a952c03 858 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 857 23.151 T 22-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 TOLA_RS08140 8c2e20554067712dc82f940b426fcca8 393 PANTHER PTHR30349:SF20 94 391 1.5E-27 T 22-04-2016 TOLA_RS08140 8c2e20554067712dc82f940b426fcca8 393 Gene3D G3DSA:1.10.443.10 206 377 1.3E-28 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS08140 8c2e20554067712dc82f940b426fcca8 393 Gene3D G3DSA:1.10.150.130 95 183 1.6E-8 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal TOLA_RS08140 8c2e20554067712dc82f940b426fcca8 393 Pfam PF00589 Phage integrase family 232 372 8.4E-14 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS08140 8c2e20554067712dc82f940b426fcca8 393 Pfam PF12167 Domain of unknown function (DUF3596) 2 63 9.7E-19 T 22-04-2016 IPR022000 Domain of unknown function (DUF3596) TOLA_RS08140 8c2e20554067712dc82f940b426fcca8 393 SUPERFAMILY SSF56349 94 380 1.32E-50 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TOLA_RS08140 8c2e20554067712dc82f940b426fcca8 393 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 95 150 7.5E-10 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TOLA_RS08140 8c2e20554067712dc82f940b426fcca8 393 PANTHER PTHR30349 94 391 1.5E-27 T 22-04-2016 TOLA_RS14655 7347d927b118a94f81e807bcd150b845 293 Gene3D G3DSA:3.90.550.10 7 238 9.9E-12 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS14655 7347d927b118a94f81e807bcd150b845 293 SUPERFAMILY SSF53448 7 260 3.49E-25 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS14655 7347d927b118a94f81e807bcd150b845 293 Pfam PF00535 Glycosyl transferase family 2 7 123 1.4E-8 T 22-04-2016 IPR001173 Glycosyltransferase 2-like TOLA_RS04385 eb0a874214369dc93e73f495f08a3df6 282 PANTHER PTHR37426 2 281 2.0E-113 T 22-04-2016 TOLA_RS04385 eb0a874214369dc93e73f495f08a3df6 282 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 275 2.9E-81 T 22-04-2016 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 TOLA_RS04385 eb0a874214369dc93e73f495f08a3df6 282 SUPERFAMILY SSF53335 9 277 1.41E-91 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04385 eb0a874214369dc93e73f495f08a3df6 282 Gene3D G3DSA:3.40.50.150 1 277 9.7E-109 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04385 eb0a874214369dc93e73f495f08a3df6 282 PANTHER PTHR37426:SF1 2 281 2.0E-113 T 22-04-2016 TOLA_RS04385 eb0a874214369dc93e73f495f08a3df6 282 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 267 42.119 T 22-04-2016 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 TOLA_RS08010 9c1209153b7e170af45ff5521c1ba824 373 Gene3D G3DSA:3.40.50.720 102 258 4.3E-28 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS08010 9c1209153b7e170af45ff5521c1ba824 373 SUPERFAMILY SSF51735 93 257 2.33E-27 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS08010 9c1209153b7e170af45ff5521c1ba824 373 PANTHER PTHR10996:SF111 1 330 2.8E-136 T 22-04-2016 TOLA_RS08010 9c1209153b7e170af45ff5521c1ba824 373 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 256 5.1E-24 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TOLA_RS08010 9c1209153b7e170af45ff5521c1ba824 373 SUPERFAMILY SSF52283 4 102 1.81E-22 T 22-04-2016 TOLA_RS08010 9c1209153b7e170af45ff5521c1ba824 373 PANTHER PTHR10996 1 330 2.8E-136 T 22-04-2016 TOLA_RS08010 9c1209153b7e170af45ff5521c1ba824 373 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 27 257 5.5E-20 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 TOLA_RS08010 9c1209153b7e170af45ff5521c1ba824 373 Gene3D G3DSA:3.40.50.720 1 101 8.4E-28 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS08010 9c1209153b7e170af45ff5521c1ba824 373 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 1 357 46.842 T 22-04-2016 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181|UniPathway: UPA00244 TOLA_RS08010 9c1209153b7e170af45ff5521c1ba824 373 Pfam PF11890 Domain of unknown function (DUF3410) 289 367 5.0E-26 T 22-04-2016 IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain GO:0046983 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181|UniPathway: UPA00244 TOLA_RS12555 8249f2249240cddd8b0069a98c6306ac 153 Pfam PF09361 Phasin protein 11 102 2.5E-7 T 22-04-2016 IPR018968 Phasin TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 PANTHER PTHR24093:SF49 13 593 0.0 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 PANTHER PTHR24093:SF49 631 688 0.0 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 313 319 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 SUPERFAMILY SSF56784 373 410 2.0E-37 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 SUPERFAMILY SSF56784 299 323 2.0E-37 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 SUPERFAMILY SSF56784 441 565 2.0E-37 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 SUPERFAMILY SSF81665 208 305 1.7E-12 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 SUPERFAMILY SSF81665 29 103 1.7E-12 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 SUPERFAMILY SSF81665 571 667 1.7E-12 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 SUPERFAMILY SSF81653 113 207 8.89E-21 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 8 686 40.308 T 22-04-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 Gene3D G3DSA:2.70.150.10 42 208 8.0E-22 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 Pfam PF00702 haloacid dehalogenase-like hydrolase 307 536 1.1E-35 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 Gene3D G3DSA:3.40.50.1000 449 569 2.8E-35 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 154 168 3.8E-24 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 545 557 3.8E-24 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 469 479 3.8E-24 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 522 541 3.8E-24 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 311 325 3.8E-24 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 Pfam PF00122 E1-E2 ATPase 72 302 1.5E-38 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 2 683 0.0 T 22-04-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 PANTHER PTHR24093 13 593 0.0 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 PANTHER PTHR24093 631 688 0.0 T 22-04-2016 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 Gene3D G3DSA:3.40.1110.10 322 448 2.0E-52 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 379 610 2.5E-47 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS06100 df4c41dfc8ae4be6a3883bd0224164d2 688 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 72 333 6.5E-31 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS02860 91011efe495f15aede90ca7b7d034bdb 297 SUPERFAMILY SSF53850 90 294 3.44E-43 T 22-04-2016 TOLA_RS02860 91011efe495f15aede90ca7b7d034bdb 297 PANTHER PTHR30537 1 292 8.2E-113 T 22-04-2016 TOLA_RS02860 91011efe495f15aede90ca7b7d034bdb 297 Gene3D G3DSA:3.40.190.10 92 177 1.5E-21 T 22-04-2016 TOLA_RS02860 91011efe495f15aede90ca7b7d034bdb 297 PANTHER PTHR30537:SF5 1 292 8.2E-113 T 22-04-2016 TOLA_RS02860 91011efe495f15aede90ca7b7d034bdb 297 SUPERFAMILY SSF46785 4 84 7.69E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02860 91011efe495f15aede90ca7b7d034bdb 297 Pfam PF03466 LysR substrate binding domain 90 292 1.1E-40 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS02860 91011efe495f15aede90ca7b7d034bdb 297 Gene3D G3DSA:1.10.10.10 3 84 6.5E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02860 91011efe495f15aede90ca7b7d034bdb 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.8E-18 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS02860 91011efe495f15aede90ca7b7d034bdb 297 Gene3D G3DSA:3.40.190.10 178 258 1.9E-8 T 22-04-2016 TOLA_RS09330 f5665e012d00027ff837b035cb62cfa3 317 PANTHER PTHR10683 2 316 4.0E-168 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS09330 f5665e012d00027ff837b035cb62cfa3 317 Pfam PF00923 Transaldolase 14 311 8.4E-101 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS09330 f5665e012d00027ff837b035cb62cfa3 317 TIGRFAM TIGR00874 talAB: transaldolase 4 315 3.2E-147 T 22-04-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS09330 f5665e012d00027ff837b035cb62cfa3 317 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS09330 f5665e012d00027ff837b035cb62cfa3 317 Hamap MF_00492 Transaldolase [tal]. 2 316 50.99 T 22-04-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS09330 f5665e012d00027ff837b035cb62cfa3 317 PANTHER PTHR10683:SF18 2 316 4.0E-168 T 22-04-2016 TOLA_RS09330 f5665e012d00027ff837b035cb62cfa3 317 SUPERFAMILY SSF51569 2 315 1.47E-113 T 22-04-2016 TOLA_RS09330 f5665e012d00027ff837b035cb62cfa3 317 Gene3D G3DSA:3.20.20.70 3 314 5.9E-128 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS09330 f5665e012d00027ff837b035cb62cfa3 317 ProSitePatterns PS00958 Transaldolase active site. 129 146 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS02270 e0aa09b3bb063444cad988eeba4e4b87 306 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 18 302 3.4E-86 T 22-04-2016 TOLA_RS02270 e0aa09b3bb063444cad988eeba4e4b87 306 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 9 303 20.108 T 22-04-2016 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 TOLA_RS02270 e0aa09b3bb063444cad988eeba4e4b87 306 PANTHER PTHR13929 4 305 3.8E-65 T 22-04-2016 TOLA_RS02270 e0aa09b3bb063444cad988eeba4e4b87 306 PIRSF PIRSF005355 1 306 1.2E-79 T 22-04-2016 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 TOLA_RS02270 e0aa09b3bb063444cad988eeba4e4b87 306 Pfam PF01040 UbiA prenyltransferase family 28 283 2.4E-37 T 22-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 TOLA_RS02270 e0aa09b3bb063444cad988eeba4e4b87 306 PANTHER PTHR13929:SF0 4 305 3.8E-65 T 22-04-2016 TOLA_RS15385 aab5f487e8a35cc61c8f9c835fe1daea 198 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 198 29.152 T 22-04-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 TOLA_RS15385 aab5f487e8a35cc61c8f9c835fe1daea 198 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 196 6.0E-57 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 TOLA_RS15385 aab5f487e8a35cc61c8f9c835fe1daea 198 PANTHER PTHR30335 2 198 4.1E-140 T 22-04-2016 TOLA_RS15385 aab5f487e8a35cc61c8f9c835fe1daea 198 PANTHER PTHR30335:SF1 2 198 4.1E-140 T 22-04-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 TOLA_RS15385 aab5f487e8a35cc61c8f9c835fe1daea 198 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 2 196 9.8E-103 T 22-04-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 TOLA_RS15385 aab5f487e8a35cc61c8f9c835fe1daea 198 PIRSF PIRSF006102 1 198 1.0E-60 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 TOLA_RS00495 13e0bc638d30c09744e3f1acc8f7fa9d 335 Gene3D G3DSA:3.30.360.10 165 309 8.2E-49 T 22-04-2016 TOLA_RS00495 13e0bc638d30c09744e3f1acc8f7fa9d 335 SUPERFAMILY SSF55347 156 309 3.52E-50 T 22-04-2016 TOLA_RS00495 13e0bc638d30c09744e3f1acc8f7fa9d 335 PANTHER PTHR32338 1 335 4.9E-144 T 22-04-2016 TOLA_RS00495 13e0bc638d30c09744e3f1acc8f7fa9d 335 SUPERFAMILY SSF51735 2 185 1.58E-40 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00495 13e0bc638d30c09744e3f1acc8f7fa9d 335 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 335 37.008 T 22-04-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS00495 13e0bc638d30c09744e3f1acc8f7fa9d 335 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 151 167 - T 22-04-2016 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS00495 13e0bc638d30c09744e3f1acc8f7fa9d 335 SMART SM00859 3 148 2.4E-46 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TOLA_RS00495 13e0bc638d30c09744e3f1acc8f7fa9d 335 Gene3D G3DSA:3.40.50.720 1 164 8.7E-55 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS00495 13e0bc638d30c09744e3f1acc8f7fa9d 335 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 147 1.4E-27 T 22-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TOLA_RS00495 13e0bc638d30c09744e3f1acc8f7fa9d 335 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 334 2.8E-114 T 22-04-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS00495 13e0bc638d30c09744e3f1acc8f7fa9d 335 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 165 312 9.8E-12 T 22-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS06540 53231bef9003364a4e15b09a83cc973b 586 Pfam PF00005 ABC transporter 355 503 7.7E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS06540 53231bef9003364a4e15b09a83cc973b 586 SUPERFAMILY SSF90123 7 319 1.44E-63 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS06540 53231bef9003364a4e15b09a83cc973b 586 Gene3D G3DSA:1.20.1560.10 7 319 1.1E-63 T 22-04-2016 TOLA_RS06540 53231bef9003364a4e15b09a83cc973b 586 PANTHER PTHR24221 4 584 4.0E-170 T 22-04-2016 TOLA_RS06540 53231bef9003364a4e15b09a83cc973b 586 SMART SM00382 364 550 8.6E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS06540 53231bef9003364a4e15b09a83cc973b 586 Pfam PF00664 ABC transporter transmembrane region 30 294 5.8E-39 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS06540 53231bef9003364a4e15b09a83cc973b 586 Gene3D G3DSA:3.40.50.300 345 568 4.0E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06540 53231bef9003364a4e15b09a83cc973b 586 SUPERFAMILY SSF52540 348 575 3.55E-76 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06540 53231bef9003364a4e15b09a83cc973b 586 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS12055 7137e30b5dc50ff3ddd3739f2159d654 123 PANTHER PTHR14289 2 123 7.2E-42 T 22-04-2016 TOLA_RS12055 7137e30b5dc50ff3ddd3739f2159d654 123 SUPERFAMILY SSF110069 2 123 2.88E-42 T 22-04-2016 IPR007474 ApaG domain TOLA_RS12055 7137e30b5dc50ff3ddd3739f2159d654 123 Pfam PF04379 Protein of unknown function (DUF525) 15 99 7.0E-33 T 22-04-2016 IPR007474 ApaG domain TOLA_RS12055 7137e30b5dc50ff3ddd3739f2159d654 123 Gene3D G3DSA:2.60.40.1470 3 122 3.4E-42 T 22-04-2016 IPR007474 ApaG domain TOLA_RS10170 8ba9fe033cd0e1c22691eaf9a3c8f85d 557 SUPERFAMILY SSF56112 199 435 9.99E-27 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS10170 8ba9fe033cd0e1c22691eaf9a3c8f85d 557 SUPERFAMILY SSF56112 101 164 9.99E-27 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS10170 8ba9fe033cd0e1c22691eaf9a3c8f85d 557 Gene3D G3DSA:3.90.1200.10 158 216 2.1E-4 T 22-04-2016 TOLA_RS10170 8ba9fe033cd0e1c22691eaf9a3c8f85d 557 PANTHER PTHR10566:SF10 30 552 4.6E-149 T 22-04-2016 TOLA_RS10170 8ba9fe033cd0e1c22691eaf9a3c8f85d 557 Pfam PF03109 ABC1 family 118 237 4.1E-31 T 22-04-2016 IPR004147 UbiB domain TOLA_RS10170 8ba9fe033cd0e1c22691eaf9a3c8f85d 557 Gene3D G3DSA:3.90.1200.10 274 371 3.7E-10 T 22-04-2016 TOLA_RS10170 8ba9fe033cd0e1c22691eaf9a3c8f85d 557 PANTHER PTHR10566 30 552 4.6E-149 T 22-04-2016 TOLA_RS12615 81b1208546cd04b5f6fc0f71e2b8c5a5 452 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 381 444 2.6E-14 T 22-04-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TOLA_RS12615 81b1208546cd04b5f6fc0f71e2b8c5a5 452 Pfam PF10996 Beta-Casp domain 248 367 2.6E-21 T 22-04-2016 IPR022712 Beta-Casp domain TOLA_RS12615 81b1208546cd04b5f6fc0f71e2b8c5a5 452 PANTHER PTHR11203:SF11 1 452 3.9E-108 T 22-04-2016 TOLA_RS12615 81b1208546cd04b5f6fc0f71e2b8c5a5 452 Pfam PF12706 Beta-lactamase superfamily domain 25 213 2.5E-13 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS12615 81b1208546cd04b5f6fc0f71e2b8c5a5 452 SMART SM01027 248 367 3.8E-48 T 22-04-2016 IPR022712 Beta-Casp domain TOLA_RS12615 81b1208546cd04b5f6fc0f71e2b8c5a5 452 SUPERFAMILY SSF56281 2 446 7.21E-127 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS12615 81b1208546cd04b5f6fc0f71e2b8c5a5 452 PANTHER PTHR11203 1 452 3.9E-108 T 22-04-2016 TOLA_RS12615 81b1208546cd04b5f6fc0f71e2b8c5a5 452 SMART SM00849 14 224 9.0E-9 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS12615 81b1208546cd04b5f6fc0f71e2b8c5a5 452 Gene3D G3DSA:3.60.15.10 4 101 2.6E-47 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS12615 81b1208546cd04b5f6fc0f71e2b8c5a5 452 Gene3D G3DSA:3.60.15.10 136 255 2.6E-47 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS10080 24be0130a253b7d19c41d282cd68b755 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 207 3.5E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10080 24be0130a253b7d19c41d282cd68b755 222 SUPERFAMILY SSF161098 16 202 1.74E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10080 24be0130a253b7d19c41d282cd68b755 222 PANTHER PTHR30614 1 222 1.2E-93 T 22-04-2016 TOLA_RS10080 24be0130a253b7d19c41d282cd68b755 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 2.4E-31 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 TOLA_RS10080 24be0130a253b7d19c41d282cd68b755 222 PANTHER PTHR30614:SF18 1 222 1.2E-93 T 22-04-2016 TOLA_RS10080 24be0130a253b7d19c41d282cd68b755 222 Gene3D G3DSA:1.10.3720.10 13 207 3.7E-43 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04615 f41cf5040f4497408491a48d8a85ff8b 246 PANTHER PTHR30133 3 246 5.3E-140 T 22-04-2016 TOLA_RS04615 f41cf5040f4497408491a48d8a85ff8b 246 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 73 2.2E-15 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 TOLA_RS04615 f41cf5040f4497408491a48d8a85ff8b 246 Gene3D G3DSA:1.10.3720.10 113 240 1.4E-44 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04615 f41cf5040f4497408491a48d8a85ff8b 246 Gene3D G3DSA:1.10.3720.10 10 81 1.4E-44 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04615 f41cf5040f4497408491a48d8a85ff8b 246 SUPERFAMILY SSF161098 110 227 3.66E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04615 f41cf5040f4497408491a48d8a85ff8b 246 SUPERFAMILY SSF161098 11 78 3.66E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04615 f41cf5040f4497408491a48d8a85ff8b 246 PANTHER PTHR30133:SF3 3 246 5.3E-140 T 22-04-2016 TOLA_RS04615 f41cf5040f4497408491a48d8a85ff8b 246 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 237 1.1E-23 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09135 07fc58d21a9323dd9c1e64838fce4b9b 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 59 4.8E-11 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS09135 07fc58d21a9323dd9c1e64838fce4b9b 343 Gene3D G3DSA:3.40.50.2300 66 184 1.7E-42 T 22-04-2016 TOLA_RS09135 07fc58d21a9323dd9c1e64838fce4b9b 343 Gene3D G3DSA:1.10.260.40 12 65 1.1E-18 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS09135 07fc58d21a9323dd9c1e64838fce4b9b 343 PANTHER PTHR30146 11 341 3.9E-94 T 22-04-2016 TOLA_RS09135 07fc58d21a9323dd9c1e64838fce4b9b 343 PANTHER PTHR30146:SF27 11 341 3.9E-94 T 22-04-2016 TOLA_RS09135 07fc58d21a9323dd9c1e64838fce4b9b 343 SMART SM00354 11 82 8.0E-23 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS09135 07fc58d21a9323dd9c1e64838fce4b9b 343 SUPERFAMILY SSF53822 69 332 5.57E-56 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS09135 07fc58d21a9323dd9c1e64838fce4b9b 343 Pfam PF13377 Periplasmic binding protein-like domain 179 341 5.1E-21 T 22-04-2016 TOLA_RS09135 07fc58d21a9323dd9c1e64838fce4b9b 343 Gene3D G3DSA:3.40.50.2300 185 322 9.0E-26 T 22-04-2016 TOLA_RS09135 07fc58d21a9323dd9c1e64838fce4b9b 343 SUPERFAMILY SSF47413 11 70 1.05E-12 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS07695 13d06c5bfe37e95aade3ba9ebbc152fa 160 SUPERFAMILY SSF55961 1 137 1.06E-18 T 22-04-2016 TOLA_RS07695 13d06c5bfe37e95aade3ba9ebbc152fa 160 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 112 2.7E-5 T 22-04-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain TOLA_RS07695 13d06c5bfe37e95aade3ba9ebbc152fa 160 Gene3D G3DSA:3.30.530.20 2 118 2.7E-6 T 22-04-2016 IPR023393 START-like domain TOLA_RS05830 408c984771a598faf8eebd2a69abf6ff 410 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 386 2.4E-79 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 TOLA_RS05830 408c984771a598faf8eebd2a69abf6ff 410 SUPERFAMILY SSF56796 2 390 3.52E-93 T 22-04-2016 TOLA_RS05830 408c984771a598faf8eebd2a69abf6ff 410 Gene3D G3DSA:3.40.50.1970 1 207 3.0E-56 T 22-04-2016 TOLA_RS05830 408c984771a598faf8eebd2a69abf6ff 410 PANTHER PTHR11496:SF65 1 157 5.0E-183 T 22-04-2016 TOLA_RS05830 408c984771a598faf8eebd2a69abf6ff 410 PANTHER PTHR11496:SF65 182 410 5.0E-183 T 22-04-2016 TOLA_RS05830 408c984771a598faf8eebd2a69abf6ff 410 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 287 307 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS05830 408c984771a598faf8eebd2a69abf6ff 410 PANTHER PTHR11496 1 157 5.0E-183 T 22-04-2016 TOLA_RS05830 408c984771a598faf8eebd2a69abf6ff 410 PANTHER PTHR11496 182 410 5.0E-183 T 22-04-2016 TOLA_RS05830 408c984771a598faf8eebd2a69abf6ff 410 Gene3D G3DSA:1.20.1090.10 208 409 2.3E-49 T 22-04-2016 TOLA_RS07165 8bf3e790563260ab4a8c58dc7257aefb 301 Pfam PF08902 Domain of unknown function (DUF1848) 2 270 4.2E-102 T 22-04-2016 IPR014998 Protein of unknown function DUF1848 TOLA_RS12115 5271f3890f950816272ae40dc30d690a 390 PRINTS PR00721 Stomatin signature 78 100 1.9E-5 T 22-04-2016 IPR001972 Stomatin family GO:0016020 TOLA_RS12115 5271f3890f950816272ae40dc30d690a 390 PRINTS PR00721 Stomatin signature 181 204 1.9E-5 T 22-04-2016 IPR001972 Stomatin family GO:0016020 TOLA_RS12115 5271f3890f950816272ae40dc30d690a 390 PRINTS PR00721 Stomatin signature 125 146 1.9E-5 T 22-04-2016 IPR001972 Stomatin family GO:0016020 TOLA_RS12115 5271f3890f950816272ae40dc30d690a 390 SMART SM00244 71 231 2.6E-41 T 22-04-2016 IPR001107 Band 7 domain TOLA_RS12115 5271f3890f950816272ae40dc30d690a 390 SUPERFAMILY SSF117892 104 236 5.1E-21 T 22-04-2016 IPR001107 Band 7 domain TOLA_RS12115 5271f3890f950816272ae40dc30d690a 390 Pfam PF01145 SPFH domain / Band 7 family 75 247 5.3E-27 T 22-04-2016 IPR001107 Band 7 domain TOLA_RS12115 5271f3890f950816272ae40dc30d690a 390 PANTHER PTHR10264 5 369 6.1E-153 T 22-04-2016 IPR001972 Stomatin family GO:0016020 TOLA_RS12115 5271f3890f950816272ae40dc30d690a 390 TIGRFAM TIGR01933 hflK: HflK protein 73 334 2.3E-111 T 22-04-2016 IPR010201 HflK GO:0016021 TOLA_RS12115 5271f3890f950816272ae40dc30d690a 390 PANTHER PTHR10264:SF51 5 369 6.1E-153 T 22-04-2016 IPR010201 HflK GO:0016021 TOLA_RS12115 5271f3890f950816272ae40dc30d690a 390 Pfam PF12221 Bacterial membrane protein N terminal 1 49 4.0E-13 T 22-04-2016 IPR020980 Menbrane protein HflK, N-terminal TOLA_RS10130 39d1702b0e6a8435494a6954df6ed259 221 SUPERFAMILY SSF69118 8 216 1.6E-38 T 22-04-2016 IPR029032 AhpD-like TOLA_RS10130 39d1702b0e6a8435494a6954df6ed259 221 Gene3D G3DSA:1.20.1290.10 132 194 4.1E-11 T 22-04-2016 IPR029032 AhpD-like TOLA_RS10130 39d1702b0e6a8435494a6954df6ed259 221 Gene3D G3DSA:1.20.1290.10 7 83 5.0E-10 T 22-04-2016 IPR029032 AhpD-like TOLA_RS10130 39d1702b0e6a8435494a6954df6ed259 221 PANTHER PTHR33570:SF4 130 195 4.0E-12 T 22-04-2016 TOLA_RS10130 39d1702b0e6a8435494a6954df6ed259 221 Pfam PF02627 Carboxymuconolactone decarboxylase family 128 212 1.8E-11 T 22-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS10130 39d1702b0e6a8435494a6954df6ed259 221 PANTHER PTHR33570 130 195 4.0E-12 T 22-04-2016 TOLA_RS10925 df6fd738eeed3f597d47b16f4256e218 442 SUPERFAMILY SSF55729 299 419 2.4E-20 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS10925 df6fd738eeed3f597d47b16f4256e218 442 Pfam PF00583 Acetyltransferase (GNAT) family 341 414 2.8E-9 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS10925 df6fd738eeed3f597d47b16f4256e218 442 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 442 215.012 T 22-04-2016 IPR010167 Amino-acid N-acetyltransferase (ArgA) GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068 TOLA_RS10925 df6fd738eeed3f597d47b16f4256e218 442 PANTHER PTHR30602 1 442 8.4E-254 T 22-04-2016 TOLA_RS10925 df6fd738eeed3f597d47b16f4256e218 442 Pfam PF00696 Amino acid kinase family 27 268 1.9E-26 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS10925 df6fd738eeed3f597d47b16f4256e218 442 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 9 442 1.4E-188 T 22-04-2016 IPR010167 Amino-acid N-acetyltransferase (ArgA) GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068 TOLA_RS10925 df6fd738eeed3f597d47b16f4256e218 442 SUPERFAMILY SSF53633 9 293 4.84E-66 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS10925 df6fd738eeed3f597d47b16f4256e218 442 Gene3D G3DSA:3.40.630.30 296 440 7.5E-41 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS10925 df6fd738eeed3f597d47b16f4256e218 442 PANTHER PTHR30602:SF3 1 442 8.4E-254 T 22-04-2016 TOLA_RS10925 df6fd738eeed3f597d47b16f4256e218 442 PIRSF PIRSF000423 1 442 1.1E-196 T 22-04-2016 IPR010167 Amino-acid N-acetyltransferase (ArgA) GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068 TOLA_RS10925 df6fd738eeed3f597d47b16f4256e218 442 Gene3D G3DSA:3.40.1160.10 24 291 1.3E-64 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS07495 c537464c6803d47d9d9cd4e14c2aabea 356 PANTHER PTHR32196 1 349 1.7E-73 T 22-04-2016 TOLA_RS07495 c537464c6803d47d9d9cd4e14c2aabea 356 Pfam PF02653 Branched-chain amino acid transport system / permease component 61 335 1.8E-40 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS07495 c537464c6803d47d9d9cd4e14c2aabea 356 PANTHER PTHR32196:SF22 1 349 1.7E-73 T 22-04-2016 TOLA_RS07960 352d228249a311ff3e2465dc08023593 270 SUPERFAMILY SSF52540 1 268 1.28E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07960 352d228249a311ff3e2465dc08023593 270 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 268 3.8E-112 T 22-04-2016 IPR010223 ATP binding protein MinD, bacterial-type GO:0000918|GO:0016887 TOLA_RS07960 352d228249a311ff3e2465dc08023593 270 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 217 1.4E-28 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TOLA_RS07960 352d228249a311ff3e2465dc08023593 270 PANTHER PTHR13696 1 258 2.4E-93 T 22-04-2016 TOLA_RS07960 352d228249a311ff3e2465dc08023593 270 PIRSF PIRSF003092 1 270 2.2E-98 T 22-04-2016 IPR025501 ATP binding protein MinD TOLA_RS07960 352d228249a311ff3e2465dc08023593 270 PANTHER PTHR13696:SF1 1 258 2.4E-93 T 22-04-2016 TOLA_RS07960 352d228249a311ff3e2465dc08023593 270 Gene3D G3DSA:3.40.50.300 1 248 7.3E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04790 4c84ddfe259bad4f554bb2e4355830c6 334 PANTHER PTHR26402 4 106 3.3E-32 T 22-04-2016 TOLA_RS04790 4c84ddfe259bad4f554bb2e4355830c6 334 SMART SM00448 4 116 1.1E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS04790 4c84ddfe259bad4f554bb2e4355830c6 334 Gene3D G3DSA:3.40.50.2300 4 119 1.8E-28 T 22-04-2016 TOLA_RS04790 4c84ddfe259bad4f554bb2e4355830c6 334 Pfam PF00072 Response regulator receiver domain 6 109 4.7E-22 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS04790 4c84ddfe259bad4f554bb2e4355830c6 334 SUPERFAMILY SSF52172 1 117 4.7E-32 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 Gene3D G3DSA:3.40.50.1370 1 136 1.6E-46 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 140 5.7E-42 T 22-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 PANTHER PTHR11405 1 302 3.2E-109 T 22-04-2016 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 147 298 1.8E-43 T 22-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 Gene3D G3DSA:3.40.50.1370 137 287 1.7E-50 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 9.5E-19 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 45 64 9.5E-19 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 9.5E-19 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 SUPERFAMILY SSF53671 1 301 4.32E-86 T 22-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 279 290 7.9E-22 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 218 228 7.9E-22 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 116 130 7.9E-22 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 43 57 7.9E-22 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 76 89 7.9E-22 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 2 300 1.6E-97 T 22-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TOLA_RS00505 da0f74535a52b2bbb0de08da89c76005 303 PANTHER PTHR11405:SF1 1 302 3.2E-109 T 22-04-2016 TOLA_RS10375 c54308313f90d40d9aec0b33c088ac0b 293 Pfam PF00483 Nucleotidyl transferase 2 235 8.8E-69 T 22-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 TOLA_RS10375 c54308313f90d40d9aec0b33c088ac0b 293 PANTHER PTHR22572 2 269 1.2E-171 T 22-04-2016 TOLA_RS10375 c54308313f90d40d9aec0b33c088ac0b 293 Gene3D G3DSA:3.90.550.10 1 262 1.1E-67 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS10375 c54308313f90d40d9aec0b33c088ac0b 293 PANTHER PTHR22572:SF105 2 269 1.2E-171 T 22-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 TOLA_RS10375 c54308313f90d40d9aec0b33c088ac0b 293 SUPERFAMILY SSF53448 1 287 3.03E-91 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS10375 c54308313f90d40d9aec0b33c088ac0b 293 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 4.8E-152 T 22-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 TOLA_RS09415 ab730ecc5828ccde623a36bad6007296 401 Gene3D G3DSA:1.20.1250.20 21 198 4.9E-27 T 22-04-2016 TOLA_RS09415 ab730ecc5828ccde623a36bad6007296 401 Gene3D G3DSA:1.20.1250.20 220 392 2.3E-13 T 22-04-2016 TOLA_RS09415 ab730ecc5828ccde623a36bad6007296 401 Pfam PF07690 Major Facilitator Superfamily 25 336 3.4E-29 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS09415 ab730ecc5828ccde623a36bad6007296 401 PANTHER PTHR23501:SF28 18 394 4.8E-142 T 22-04-2016 TOLA_RS09415 ab730ecc5828ccde623a36bad6007296 401 SUPERFAMILY SSF103473 16 394 2.22E-51 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS09415 ab730ecc5828ccde623a36bad6007296 401 PANTHER PTHR23501 18 394 4.8E-142 T 22-04-2016 TOLA_RS01250 bc5beb3760950455ed81026b805eb2eb 239 SUPERFAMILY SSF56784 9 236 1.63E-42 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS01250 bc5beb3760950455ed81026b805eb2eb 239 Gene3D G3DSA:3.40.50.1000 9 233 8.6E-33 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS01250 bc5beb3760950455ed81026b805eb2eb 239 Pfam PF13419 Haloacid dehalogenase-like hydrolase 15 207 2.7E-16 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS01250 bc5beb3760950455ed81026b805eb2eb 239 PANTHER PTHR12725 1 237 3.2E-51 T 22-04-2016 TOLA_RS01250 bc5beb3760950455ed81026b805eb2eb 239 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 198 1.5E-8 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS01250 bc5beb3760950455ed81026b805eb2eb 239 PANTHER PTHR12725:SF65 1 237 3.2E-51 T 22-04-2016 TOLA_RS07975 8e28e6f76350e76af964553e368b94f6 252 SUPERFAMILY SSF102705 1 251 2.49E-79 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TOLA_RS07975 8e28e6f76350e76af964553e368b94f6 252 Gene3D G3DSA:3.40.1390.30 109 218 7.2E-26 T 22-04-2016 TOLA_RS07975 8e28e6f76350e76af964553e368b94f6 252 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 251 2.0E-59 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TOLA_RS07975 8e28e6f76350e76af964553e368b94f6 252 PANTHER PTHR13799 1 249 2.2E-76 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TOLA_RS07975 8e28e6f76350e76af964553e368b94f6 252 Gene3D G3DSA:3.40.1390.30 1 108 5.3E-38 T 22-04-2016 TOLA_RS07975 8e28e6f76350e76af964553e368b94f6 252 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 240 2.9E-60 T 22-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TOLA_RS14460 4f24d3dbfc87485bd3f60cb02bc10400 281 PANTHER PTHR21581:SF8 34 272 1.8E-74 T 22-04-2016 TOLA_RS14460 4f24d3dbfc87485bd3f60cb02bc10400 281 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 32 255 5.1E-59 T 22-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 TOLA_RS14460 4f24d3dbfc87485bd3f60cb02bc10400 281 Gene3D G3DSA:3.40.710.10 30 272 4.5E-67 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS14460 4f24d3dbfc87485bd3f60cb02bc10400 281 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 112 129 2.1E-11 T 22-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TOLA_RS14460 4f24d3dbfc87485bd3f60cb02bc10400 281 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 139 152 2.1E-11 T 22-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TOLA_RS14460 4f24d3dbfc87485bd3f60cb02bc10400 281 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 62 73 2.1E-11 T 22-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TOLA_RS14460 4f24d3dbfc87485bd3f60cb02bc10400 281 SUPERFAMILY SSF56601 34 274 6.14E-58 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS14460 4f24d3dbfc87485bd3f60cb02bc10400 281 PANTHER PTHR21581 34 272 1.8E-74 T 22-04-2016 TOLA_RS09270 5686c12553f3d13c4d6892a2ae9a99b2 214 Pfam PF08241 Methyltransferase domain 44 129 2.1E-19 T 22-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 TOLA_RS09270 5686c12553f3d13c4d6892a2ae9a99b2 214 Gene3D G3DSA:3.40.50.150 5 179 1.7E-35 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS09270 5686c12553f3d13c4d6892a2ae9a99b2 214 PANTHER PTHR10108 7 208 1.2E-29 T 22-04-2016 TOLA_RS09270 5686c12553f3d13c4d6892a2ae9a99b2 214 SUPERFAMILY SSF53335 5 177 7.59E-34 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS10070 adfd972948eb0280f515e224e824b5ae 124 Gene3D G3DSA:3.10.450.50 1 124 7.0E-58 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS10070 adfd972948eb0280f515e224e824b5ae 124 SUPERFAMILY SSF54427 2 123 3.02E-38 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS10070 adfd972948eb0280f515e224e824b5ae 124 Pfam PF11533 Protein of unknown function (DUF3225) 1 123 2.9E-59 T 22-04-2016 IPR024507 Protein of unknown function DUF3225 TOLA_RS12605 613a40dcdcc7b01f81a388df015a2250 298 SMART SM01400 4 118 9.8E-30 T 22-04-2016 TOLA_RS12605 613a40dcdcc7b01f81a388df015a2250 298 SUPERFAMILY SSF53271 9 159 1.84E-35 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS12605 613a40dcdcc7b01f81a388df015a2250 298 Gene3D G3DSA:3.40.50.2020 158 277 6.2E-22 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS12605 613a40dcdcc7b01f81a388df015a2250 298 PANTHER PTHR10210:SF32 6 279 2.3E-46 T 22-04-2016 TOLA_RS12605 613a40dcdcc7b01f81a388df015a2250 298 SUPERFAMILY SSF53271 159 287 1.7E-25 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS12605 613a40dcdcc7b01f81a388df015a2250 298 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 6 290 1.1E-55 T 22-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 TOLA_RS12605 613a40dcdcc7b01f81a388df015a2250 298 PANTHER PTHR10210 6 279 2.3E-46 T 22-04-2016 TOLA_RS12605 613a40dcdcc7b01f81a388df015a2250 298 Gene3D G3DSA:3.40.50.2020 6 157 1.8E-30 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS12605 613a40dcdcc7b01f81a388df015a2250 298 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 7 115 1.5E-17 T 22-04-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 TOLA_RS12605 613a40dcdcc7b01f81a388df015a2250 298 Pfam PF00156 Phosphoribosyl transferase domain 151 248 7.6E-16 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 TOLA_RS10390 e903319a4941426a50722dd764363251 480 PANTHER PTHR30576:SF4 58 480 9.9E-156 T 22-04-2016 TOLA_RS10390 e903319a4941426a50722dd764363251 480 TIGRFAM TIGR03022 WbaP_sugtrans: undecaprenyl-phosphate galactose phosphotransferase WbaP 17 480 6.1E-164 T 22-04-2016 IPR017472 Undecaprenyl-phosphate galactose phosphotransferase, WbaP GO:0000271|GO:0005886|GO:0016021|GO:0016740 TOLA_RS10390 e903319a4941426a50722dd764363251 480 Pfam PF02397 Bacterial sugar transferase 284 474 2.4E-55 T 22-04-2016 IPR003362 Bacterial sugar transferase TOLA_RS10390 e903319a4941426a50722dd764363251 480 PANTHER PTHR30576 58 480 9.9E-156 T 22-04-2016 TOLA_RS10390 e903319a4941426a50722dd764363251 480 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 20 480 1.0E-115 T 22-04-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase TOLA_RS07705 46807808377cb37663c47de884fcb07d 101 Pfam PF11006 Protein of unknown function (DUF2845) 21 97 2.0E-17 T 22-04-2016 IPR021268 Protein of unknown function DUF2845 TOLA_RS06695 eba4daadb389f20590589a3d869b29b4 239 Gene3D G3DSA:3.40.50.1010 2 143 7.6E-29 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS06695 eba4daadb389f20590589a3d869b29b4 239 Pfam PF12872 OST-HTH/LOTUS domain 158 227 2.6E-16 T 22-04-2016 IPR025605 OST-HTH/LOTUS domain TOLA_RS06695 eba4daadb389f20590589a3d869b29b4 239 Pfam PF01936 NYN domain 6 141 2.1E-31 T 22-04-2016 IPR021139 NYN domain, limkain-b1-type TOLA_RS06695 eba4daadb389f20590589a3d869b29b4 239 PANTHER PTHR35811 2 238 6.9E-60 T 22-04-2016 TOLA_RS06695 eba4daadb389f20590589a3d869b29b4 239 PANTHER PTHR35811:SF1 2 238 6.9E-60 T 22-04-2016 TOLA_RS11520 81ebb2fa0c3e44159d58f00acec5b70c 594 Gene3D G3DSA:3.40.50.300 396 575 8.0E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11520 81ebb2fa0c3e44159d58f00acec5b70c 594 Gene3D G3DSA:3.40.50.300 129 221 8.0E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11520 81ebb2fa0c3e44159d58f00acec5b70c 594 SUPERFAMILY SSF52540 393 575 1.68E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11520 81ebb2fa0c3e44159d58f00acec5b70c 594 SUPERFAMILY SSF52540 122 275 1.68E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11520 81ebb2fa0c3e44159d58f00acec5b70c 594 PANTHER PTHR30121 322 571 3.0E-26 T 22-04-2016 TOLA_RS11520 81ebb2fa0c3e44159d58f00acec5b70c 594 PANTHER PTHR30121 41 284 3.0E-26 T 22-04-2016 TOLA_RS11520 81ebb2fa0c3e44159d58f00acec5b70c 594 Pfam PF01935 Domain of unknown function DUF87 130 276 5.7E-19 T 22-04-2016 IPR002789 Helicase HerA, central domain TOLA_RS10605 0a5cce570aa17cbc270f586b9a0482ea 372 Gene3D G3DSA:1.10.3210.10 183 341 4.9E-18 T 22-04-2016 IPR006674 HD domain TOLA_RS10605 0a5cce570aa17cbc270f586b9a0482ea 372 Gene3D G3DSA:3.30.450.40 12 152 8.6E-9 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS10605 0a5cce570aa17cbc270f586b9a0482ea 372 SMART SM00471 179 327 4.4E-8 T 22-04-2016 IPR003607 HD/PDEase domain TOLA_RS10605 0a5cce570aa17cbc270f586b9a0482ea 372 SUPERFAMILY SSF55781 33 152 4.66E-12 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS10605 0a5cce570aa17cbc270f586b9a0482ea 372 SUPERFAMILY SSF109604 178 356 1.73E-28 T 22-04-2016 TOLA_RS10605 0a5cce570aa17cbc270f586b9a0482ea 372 Pfam PF01966 HD domain 185 317 1.1E-18 T 22-04-2016 IPR006674 HD domain TOLA_RS05920 c6d769a86eb5df447be072af33e1a690 294 SUPERFAMILY SSF116734 99 294 1.39E-31 T 22-04-2016 TOLA_RS05920 c6d769a86eb5df447be072af33e1a690 294 Pfam PF01420 Type I restriction modification DNA specificity domain 13 77 8.0E-14 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TOLA_RS05920 c6d769a86eb5df447be072af33e1a690 294 Pfam PF01420 Type I restriction modification DNA specificity domain 99 275 4.0E-17 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TOLA_RS05920 c6d769a86eb5df447be072af33e1a690 294 SUPERFAMILY SSF116734 9 95 6.54E-19 T 22-04-2016 TOLA_RS05920 c6d769a86eb5df447be072af33e1a690 294 PANTHER PTHR30408 5 109 3.9E-18 T 22-04-2016 TOLA_RS05920 c6d769a86eb5df447be072af33e1a690 294 PANTHER PTHR30408:SF2 5 109 3.9E-18 T 22-04-2016 TOLA_RS01625 188ae094b627cc41cb39f2d50f81e934 123 Pfam PF01925 Sulfite exporter TauE/SafE 8 116 1.4E-21 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 TOLA_RS01625 188ae094b627cc41cb39f2d50f81e934 123 PANTHER PTHR30269:SF9 1 120 1.9E-25 T 22-04-2016 TOLA_RS01625 188ae094b627cc41cb39f2d50f81e934 123 PANTHER PTHR30269 1 120 1.9E-25 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 TOLA_RS10265 9ad187fbcfcd81a48add1178bc473d76 404 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 395 54.268 T 22-04-2016 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|UniPathway: UPA00266 TOLA_RS10265 9ad187fbcfcd81a48add1178bc473d76 404 Gene3D G3DSA:3.40.640.10 17 253 4.6E-96 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS10265 9ad187fbcfcd81a48add1178bc473d76 404 PANTHER PTHR11601 4 404 2.1E-230 T 22-04-2016 TOLA_RS10265 9ad187fbcfcd81a48add1178bc473d76 404 SUPERFAMILY SSF53383 5 391 5.79E-113 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS10265 9ad187fbcfcd81a48add1178bc473d76 404 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 1 404 9.5E-229 T 22-04-2016 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|UniPathway: UPA00266 TOLA_RS10265 9ad187fbcfcd81a48add1178bc473d76 404 Pfam PF00266 Aminotransferase class-V 5 368 1.6E-87 T 22-04-2016 IPR000192 Aminotransferase class V domain TOLA_RS10265 9ad187fbcfcd81a48add1178bc473d76 404 PANTHER PTHR11601:SF45 4 404 2.1E-230 T 22-04-2016 TOLA_RS10265 9ad187fbcfcd81a48add1178bc473d76 404 PIRSF PIRSF005572 2 384 8.6E-133 T 22-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 TOLA_RS10265 9ad187fbcfcd81a48add1178bc473d76 404 Gene3D G3DSA:3.90.1150.10 254 374 5.2E-51 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS10265 9ad187fbcfcd81a48add1178bc473d76 404 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 22-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TOLA_RS06980 315cd7d229bf31fea815b017806b2210 198 PANTHER PTHR12725 2 192 3.4E-35 T 22-04-2016 TOLA_RS06980 315cd7d229bf31fea815b017806b2210 198 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 48 180 5.1E-15 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS06980 315cd7d229bf31fea815b017806b2210 198 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 163 2.7E-7 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS06980 315cd7d229bf31fea815b017806b2210 198 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 125 141 2.7E-7 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS06980 315cd7d229bf31fea815b017806b2210 198 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 2.7E-7 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS06980 315cd7d229bf31fea815b017806b2210 198 Pfam PF13419 Haloacid dehalogenase-like hydrolase 54 179 5.5E-11 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS06980 315cd7d229bf31fea815b017806b2210 198 PANTHER PTHR12725:SF63 2 192 3.4E-35 T 22-04-2016 TOLA_RS06980 315cd7d229bf31fea815b017806b2210 198 Gene3D G3DSA:3.40.50.1000 2 193 2.0E-36 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS06980 315cd7d229bf31fea815b017806b2210 198 SUPERFAMILY SSF56784 3 192 5.41E-37 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 PANTHER PTHR11669 1 370 2.3E-173 T 22-04-2016 TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 PANTHER PTHR11669 425 497 2.3E-173 T 22-04-2016 TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 626 748 1.5E-23 T 22-04-2016 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 PANTHER PTHR11669:SF0 1 370 2.3E-173 T 22-04-2016 TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 PANTHER PTHR11669:SF0 425 497 2.3E-173 T 22-04-2016 TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 SMART SM00382 37 178 1.1E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 3.9E-5 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 3.9E-5 T 22-04-2016 IPR001270 ClpA/B family GO:0005524 TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 Gene3D G3DSA:1.20.272.10 243 361 3.2E-39 T 22-04-2016 TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 355 2.4E-134 T 22-04-2016 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 SUPERFAMILY SSF48019 243 361 2.55E-28 T 22-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 Gene3D G3DSA:3.40.50.300 15 166 1.6E-68 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 Pfam PF13177 DNA polymerase III, delta subunit 20 178 8.4E-46 T 22-04-2016 TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 Gene3D G3DSA:1.10.8.60 167 242 6.6E-32 T 22-04-2016 TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 SUPERFAMILY SSF52540 34 223 2.29E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11255 c910d0158ec8e11c6493e378774bf422 760 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 359 6.5E-28 T 22-04-2016 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 TOLA_RS14640 7650f1fcb83239fb86ab625a381a6fc7 130 PANTHER PTHR10491 14 113 3.2E-15 T 22-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family TOLA_RS14640 7650f1fcb83239fb86ab625a381a6fc7 130 Pfam PF04321 RmlD substrate binding domain 11 116 1.1E-23 T 22-04-2016 IPR029903 RmlD-like substrate binding domain TOLA_RS14640 7650f1fcb83239fb86ab625a381a6fc7 130 SUPERFAMILY SSF51735 10 122 4.23E-23 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14640 7650f1fcb83239fb86ab625a381a6fc7 130 Gene3D G3DSA:3.40.50.720 10 120 1.5E-18 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS06325 6671e33e7a255ac3352554f0c4de17a1 310 SUPERFAMILY SSF46785 6 81 9.36E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06325 6671e33e7a255ac3352554f0c4de17a1 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.1E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS06325 6671e33e7a255ac3352554f0c4de17a1 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.1E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS06325 6671e33e7a255ac3352554f0c4de17a1 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.1E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS06325 6671e33e7a255ac3352554f0c4de17a1 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 7.1E-17 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS06325 6671e33e7a255ac3352554f0c4de17a1 310 Gene3D G3DSA:1.10.10.10 7 80 4.1E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06325 6671e33e7a255ac3352554f0c4de17a1 310 PANTHER PTHR30126 3 309 6.3E-40 T 22-04-2016 TOLA_RS06325 6671e33e7a255ac3352554f0c4de17a1 310 Pfam PF03466 LysR substrate binding domain 89 302 9.3E-19 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS06325 6671e33e7a255ac3352554f0c4de17a1 310 Gene3D G3DSA:3.40.190.10 93 208 2.8E-12 T 22-04-2016 TOLA_RS06325 6671e33e7a255ac3352554f0c4de17a1 310 SUPERFAMILY SSF53850 89 300 1.71E-26 T 22-04-2016 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 PANTHER PTHR19370:SF89 17 265 2.5E-77 T 22-04-2016 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 PRINTS PR00406 Cytochrome B5 reductase signature 122 141 6.6E-8 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 PRINTS PR00406 Cytochrome B5 reductase signature 61 68 6.6E-8 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 PRINTS PR00406 Cytochrome B5 reductase signature 98 112 6.6E-8 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 PRINTS PR00406 Cytochrome B5 reductase signature 213 221 6.6E-8 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 PRINTS PR00406 Cytochrome B5 reductase signature 159 170 6.6E-8 T 22-04-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 SUPERFAMILY SSF52343 101 243 7.2E-36 T 22-04-2016 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 PANTHER PTHR19370 17 265 2.5E-77 T 22-04-2016 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 159 170 1.1E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 122 141 1.1E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 42 52 1.1E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 61 68 1.1E-5 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 Gene3D G3DSA:3.10.20.30 242 346 5.4E-26 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 295 303 - T 22-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 SUPERFAMILY SSF54292 235 347 9.31E-24 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 276 339 8.9E-12 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 SUPERFAMILY SSF63380 7 113 7.74E-25 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 Gene3D G3DSA:3.40.50.80 117 241 2.3E-34 T 22-04-2016 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 Gene3D G3DSA:2.40.30.10 13 112 1.4E-25 T 22-04-2016 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 Pfam PF00175 Oxidoreductase NAD-binding domain 125 224 1.7E-14 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TOLA_RS02605 2966af6c961fadf819e8a8f12b2ec23d 347 Pfam PF00970 Oxidoreductase FAD-binding domain 19 110 1.2E-13 T 22-04-2016 IPR008333 Oxidoreductase, FAD-binding domain TOLA_RS06370 c2ed381d3be53f8bb7b842ecfca764d6 229 SMART SM00382 32 223 7.7E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS06370 c2ed381d3be53f8bb7b842ecfca764d6 229 Pfam PF00005 ABC transporter 23 173 7.4E-34 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS06370 c2ed381d3be53f8bb7b842ecfca764d6 229 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS06370 c2ed381d3be53f8bb7b842ecfca764d6 229 PANTHER PTHR24220 5 220 4.3E-91 T 22-04-2016 TOLA_RS06370 c2ed381d3be53f8bb7b842ecfca764d6 229 PANTHER PTHR24220:SF578 5 220 4.3E-91 T 22-04-2016 TOLA_RS06370 c2ed381d3be53f8bb7b842ecfca764d6 229 SUPERFAMILY SSF52540 3 225 3.92E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06370 c2ed381d3be53f8bb7b842ecfca764d6 229 Gene3D G3DSA:3.40.50.300 3 226 6.8E-69 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09620 da9c3e725a86564fe1550dd981ea35af 227 Pfam PF00923 Transaldolase 4 203 1.3E-46 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS09620 da9c3e725a86564fe1550dd981ea35af 227 PANTHER PTHR10683:SF11 1 221 1.1E-71 T 22-04-2016 TOLA_RS09620 da9c3e725a86564fe1550dd981ea35af 227 Gene3D G3DSA:3.20.20.70 3 216 9.4E-59 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS09620 da9c3e725a86564fe1550dd981ea35af 227 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS09620 da9c3e725a86564fe1550dd981ea35af 227 PANTHER PTHR10683 1 221 1.1E-71 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS09620 da9c3e725a86564fe1550dd981ea35af 227 SUPERFAMILY SSF51569 2 218 1.87E-62 T 22-04-2016 TOLA_RS04475 1d0dfaa1fdb5ddef9e00098e81dae26c 205 Gene3D G3DSA:3.40.50.1110 20 199 2.1E-49 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain TOLA_RS04475 1d0dfaa1fdb5ddef9e00098e81dae26c 205 PANTHER PTHR30383 20 199 4.7E-39 T 22-04-2016 TOLA_RS04475 1d0dfaa1fdb5ddef9e00098e81dae26c 205 SUPERFAMILY SSF52266 20 198 4.73E-46 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain TOLA_RS04475 1d0dfaa1fdb5ddef9e00098e81dae26c 205 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 21 31 - T 22-04-2016 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 TOLA_RS04475 1d0dfaa1fdb5ddef9e00098e81dae26c 205 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 24 181 2.1E-20 T 22-04-2016 IPR013830 SGNH hydrolase-type esterase domain TOLA_RS03425 71c93b4fb3c476a78c8d833e19393777 623 Pfam PF08378 Nuclease-related domain 21 124 3.3E-6 T 22-04-2016 IPR011528 Nuclease-related domain, NERD TOLA_RS03425 71c93b4fb3c476a78c8d833e19393777 623 Gene3D G3DSA:3.40.50.300 221 429 6.3E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03425 71c93b4fb3c476a78c8d833e19393777 623 Gene3D G3DSA:3.40.50.300 430 594 5.4E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03425 71c93b4fb3c476a78c8d833e19393777 623 Pfam PF00580 UvrD/REP helicase N-terminal domain 358 402 1.9E-5 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TOLA_RS03425 71c93b4fb3c476a78c8d833e19393777 623 SUPERFAMILY SSF52540 217 594 8.69E-37 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 ProSitePatterns PS00894 DeoR-type HTH domain signature. 9 43 - T 22-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 PANTHER PTHR30363 3 248 6.9E-58 T 22-04-2016 TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 SMART SM00420 9 61 1.4E-15 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 Gene3D G3DSA:1.10.10.10 3 59 1.4E-8 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 SUPERFAMILY SSF46785 7 65 1.17E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 SMART SM01134 74 239 4.2E-54 T 22-04-2016 TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 Pfam PF08220 DeoR-like helix-turn-helix domain 9 61 2.0E-15 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 PANTHER PTHR30363:SF1 3 248 6.9E-58 T 22-04-2016 TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 Gene3D G3DSA:3.40.50.1360 78 213 3.8E-7 T 22-04-2016 TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 41 59 2.7E-7 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 27 41 2.7E-7 T 22-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 SUPERFAMILY SSF100950 77 233 6.17E-26 T 22-04-2016 TOLA_RS02295 98d5af7d90ad02bf324ba043ec807dfd 258 Pfam PF00455 DeoR C terminal sensor domain 77 231 9.4E-42 T 22-04-2016 IPR014036 DeoR C-terminal sensor domain TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 PANTHER PTHR30425 576 745 5.6E-155 T 22-04-2016 TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 PANTHER PTHR30425 374 510 5.6E-155 T 22-04-2016 TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 SUPERFAMILY SSF50978 182 389 4.95E-8 T 22-04-2016 IPR017986 WD40-repeat-containing domain GO:0005515 TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 SUPERFAMILY SSF161098 514 731 2.22E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 SUPERFAMILY SSF161098 436 541 1.26E-6 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 463 739 3.0E-10 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 Gene3D G3DSA:2.130.10.10 223 399 4.3E-6 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 Gene3D G3DSA:2.130.10.10 115 151 4.3E-6 T 22-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 Gene3D G3DSA:1.10.3720.10 426 508 1.6E-44 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 Gene3D G3DSA:1.10.3720.10 581 742 1.6E-44 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 Gene3D G3DSA:1.10.3720.10 33 55 1.6E-44 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 PANTHER PTHR30425:SF3 576 745 5.6E-155 T 22-04-2016 TOLA_RS10480 866e526e2e723fee9c4b89ec9e48a861 745 PANTHER PTHR30425:SF3 374 510 5.6E-155 T 22-04-2016 TOLA_RS00240 caac7d4bf091b6a50f357106bac7ccce 319 Gene3D G3DSA:3.60.15.10 53 309 4.8E-74 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS00240 caac7d4bf091b6a50f357106bac7ccce 319 PANTHER PTHR15032 57 311 3.9E-93 T 22-04-2016 TOLA_RS00240 caac7d4bf091b6a50f357106bac7ccce 319 PIRSF PIRSF038896 14 310 3.1E-95 T 22-04-2016 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 TOLA_RS00240 caac7d4bf091b6a50f357106bac7ccce 319 Pfam PF12706 Beta-lactamase superfamily domain 74 265 1.1E-39 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS00240 caac7d4bf091b6a50f357106bac7ccce 319 PANTHER PTHR15032:SF4 57 311 3.9E-93 T 22-04-2016 TOLA_RS00240 caac7d4bf091b6a50f357106bac7ccce 319 SUPERFAMILY SSF56281 58 291 1.21E-39 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS00915 84f2e4917cc1425637e35a1463956b36 256 Gene3D G3DSA:1.10.3720.10 49 250 3.1E-48 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00915 84f2e4917cc1425637e35a1463956b36 256 SUPERFAMILY SSF161098 49 242 7.98E-44 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00915 84f2e4917cc1425637e35a1463956b36 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 248 5.8E-22 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00915 84f2e4917cc1425637e35a1463956b36 256 PANTHER PTHR30614 7 256 8.9E-71 T 22-04-2016 TOLA_RS00915 84f2e4917cc1425637e35a1463956b36 256 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 51 145 1.8E-25 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 TOLA_RS03975 5538486d283db359f1a340b9621d4903 333 Gene3D G3DSA:3.40.50.2300 176 332 7.8E-42 T 22-04-2016 TOLA_RS03975 5538486d283db359f1a340b9621d4903 333 SMART SM00354 7 77 7.5E-25 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS03975 5538486d283db359f1a340b9621d4903 333 PANTHER PTHR30146:SF2 6 333 1.7E-159 T 22-04-2016 TOLA_RS03975 5538486d283db359f1a340b9621d4903 333 SUPERFAMILY SSF53822 64 318 4.91E-59 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS03975 5538486d283db359f1a340b9621d4903 333 SUPERFAMILY SSF47413 6 65 8.19E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS03975 5538486d283db359f1a340b9621d4903 333 Gene3D G3DSA:1.10.260.40 6 61 5.8E-17 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS03975 5538486d283db359f1a340b9621d4903 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 2.8E-15 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS03975 5538486d283db359f1a340b9621d4903 333 Gene3D G3DSA:3.40.50.2300 64 175 9.9E-40 T 22-04-2016 TOLA_RS03975 5538486d283db359f1a340b9621d4903 333 PANTHER PTHR30146 6 333 1.7E-159 T 22-04-2016 TOLA_RS03975 5538486d283db359f1a340b9621d4903 333 Pfam PF13377 Periplasmic binding protein-like domain 175 332 5.7E-27 T 22-04-2016 TOLA_RS10835 8ae982d3f0a1dd0aee665b4bcf0499a0 259 Gene3D G3DSA:1.10.287.460 30 132 2.0E-34 T 22-04-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 TOLA_RS10835 8ae982d3f0a1dd0aee665b4bcf0499a0 259 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 27 147 3.0E-35 T 22-04-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 TOLA_RS10835 8ae982d3f0a1dd0aee665b4bcf0499a0 259 Gene3D G3DSA:3.10.50.40 133 243 4.4E-45 T 22-04-2016 TOLA_RS10835 8ae982d3f0a1dd0aee665b4bcf0499a0 259 PANTHER PTHR10516 96 106 9.1E-57 T 22-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type TOLA_RS10835 8ae982d3f0a1dd0aee665b4bcf0499a0 259 PANTHER PTHR10516 125 243 9.1E-57 T 22-04-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type TOLA_RS10835 8ae982d3f0a1dd0aee665b4bcf0499a0 259 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 154 241 1.9E-27 T 22-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 TOLA_RS10835 8ae982d3f0a1dd0aee665b4bcf0499a0 259 SUPERFAMILY SSF54534 37 243 3.82E-62 T 22-04-2016 TOLA_RS10835 8ae982d3f0a1dd0aee665b4bcf0499a0 259 PANTHER PTHR10516:SF320 96 106 9.1E-57 T 22-04-2016 TOLA_RS10835 8ae982d3f0a1dd0aee665b4bcf0499a0 259 PANTHER PTHR10516:SF320 125 243 9.1E-57 T 22-04-2016 TOLA_RS15220 80f9c049900a31032e06a383346119b6 173 Pfam PF05239 PRC-barrel domain 96 167 1.2E-10 T 22-04-2016 IPR027275 PRC-barrel domain TOLA_RS15220 80f9c049900a31032e06a383346119b6 173 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 5 173 1.1E-57 T 22-04-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TOLA_RS15220 80f9c049900a31032e06a383346119b6 173 Gene3D G3DSA:2.40.30.60 3 91 4.0E-32 T 22-04-2016 IPR002676 RimM protein GO:0006364 TOLA_RS15220 80f9c049900a31032e06a383346119b6 173 SUPERFAMILY SSF50346 97 173 3.14E-20 T 22-04-2016 IPR011033 PRC-barrel-like TOLA_RS15220 80f9c049900a31032e06a383346119b6 173 PANTHER PTHR33692 2 171 6.1E-63 T 22-04-2016 TOLA_RS15220 80f9c049900a31032e06a383346119b6 173 Gene3D G3DSA:2.30.30.240 97 173 2.0E-30 T 22-04-2016 TOLA_RS15220 80f9c049900a31032e06a383346119b6 173 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 4 173 24.825 T 22-04-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TOLA_RS15220 80f9c049900a31032e06a383346119b6 173 SUPERFAMILY SSF50447 5 90 2.35E-25 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain TOLA_RS15220 80f9c049900a31032e06a383346119b6 173 Pfam PF01782 RimM N-terminal domain 6 87 3.8E-26 T 22-04-2016 IPR002676 RimM protein GO:0006364 TOLA_RS11650 504d33cee82e2cc6ed30315a37b2cc23 149 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 109 141 1.0E-10 T 22-04-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 TOLA_RS11650 504d33cee82e2cc6ed30315a37b2cc23 149 PANTHER PTHR33823:SF2 6 148 1.2E-67 T 22-04-2016 TOLA_RS11650 504d33cee82e2cc6ed30315a37b2cc23 149 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 30 138 1.4E-51 T 22-04-2016 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 TOLA_RS11650 504d33cee82e2cc6ed30315a37b2cc23 149 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 26 148 29.648 T 22-04-2016 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 TOLA_RS11650 504d33cee82e2cc6ed30315a37b2cc23 149 SUPERFAMILY SSF57716 109 147 5.42E-10 T 22-04-2016 TOLA_RS11650 504d33cee82e2cc6ed30315a37b2cc23 149 PRINTS PR00618 DksA/TraR zinc finger signature 124 136 8.0E-5 T 22-04-2016 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria TOLA_RS11650 504d33cee82e2cc6ed30315a37b2cc23 149 PRINTS PR00618 DksA/TraR zinc finger signature 112 123 8.0E-5 T 22-04-2016 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria TOLA_RS11650 504d33cee82e2cc6ed30315a37b2cc23 149 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 112 136 - T 22-04-2016 IPR020458 Zinc finger, DksA/TraR C4-type conserved site TOLA_RS11650 504d33cee82e2cc6ed30315a37b2cc23 149 PANTHER PTHR33823 6 148 1.2E-67 T 22-04-2016 TOLA_RS11650 504d33cee82e2cc6ed30315a37b2cc23 149 SUPERFAMILY SSF109635 8 108 6.41E-37 T 22-04-2016 TOLA_RS01775 180dc30939d670f03243ec9921f02837 212 PANTHER PTHR11649 10 211 9.6E-55 T 22-04-2016 TOLA_RS01775 180dc30939d670f03243ec9921f02837 212 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 12 195 7.8E-73 T 22-04-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0000917|GO:0005525 TOLA_RS01775 180dc30939d670f03243ec9921f02837 212 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 16 199 27.516 T 22-04-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0000917|GO:0005525 TOLA_RS01775 180dc30939d670f03243ec9921f02837 212 Pfam PF01926 50S ribosome-binding GTPase 30 148 2.8E-19 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS01775 180dc30939d670f03243ec9921f02837 212 SUPERFAMILY SSF52540 7 199 2.72E-34 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01775 180dc30939d670f03243ec9921f02837 212 Gene3D G3DSA:3.40.50.300 12 200 3.0E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00770 dd0ea4972206edf8ea844e1351558345 480 PIRSF PIRSF006247 1 480 3.3E-164 T 22-04-2016 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 TOLA_RS00770 dd0ea4972206edf8ea844e1351558345 480 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 85 463 9.7E-107 T 22-04-2016 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 TOLA_RS00770 dd0ea4972206edf8ea844e1351558345 480 Pfam PF02386 Cation transport protein 63 472 6.0E-57 T 22-04-2016 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 TOLA_RS00770 dd0ea4972206edf8ea844e1351558345 480 PANTHER PTHR32024:SF3 1 480 4.1E-239 T 22-04-2016 TOLA_RS00770 dd0ea4972206edf8ea844e1351558345 480 PANTHER PTHR32024 1 480 4.1E-239 T 22-04-2016 TOLA_RS03990 bf2f16be3d68b0b68507b17964f7b6bf 174 Gene3D G3DSA:3.40.50.300 2 167 3.7E-72 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03990 bf2f16be3d68b0b68507b17964f7b6bf 174 PANTHER PTHR11603 1 167 3.2E-85 T 22-04-2016 TOLA_RS03990 bf2f16be3d68b0b68507b17964f7b6bf 174 Pfam PF01202 Shikimate kinase 12 121 1.1E-11 T 22-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 TOLA_RS03990 bf2f16be3d68b0b68507b17964f7b6bf 174 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 6 165 4.5E-67 T 22-04-2016 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530|UniPathway: UPA00792 TOLA_RS03990 bf2f16be3d68b0b68507b17964f7b6bf 174 SUPERFAMILY SSF52540 3 167 1.31E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07480 9cb8efdd6151a236a14490eb4e82ea31 396 SUPERFAMILY SSF53383 1 395 1.82E-117 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS07480 9cb8efdd6151a236a14490eb4e82ea31 396 PANTHER PTHR11879 1 396 1.9E-247 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 TOLA_RS07480 9cb8efdd6151a236a14490eb4e82ea31 396 PRINTS PR00799 Aspartate aminotransferase signature 273 298 9.3E-41 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 TOLA_RS07480 9cb8efdd6151a236a14490eb4e82ea31 396 PRINTS PR00799 Aspartate aminotransferase signature 341 359 9.3E-41 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 TOLA_RS07480 9cb8efdd6151a236a14490eb4e82ea31 396 PRINTS PR00799 Aspartate aminotransferase signature 175 194 9.3E-41 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 TOLA_RS07480 9cb8efdd6151a236a14490eb4e82ea31 396 PRINTS PR00799 Aspartate aminotransferase signature 206 218 9.3E-41 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 TOLA_RS07480 9cb8efdd6151a236a14490eb4e82ea31 396 PANTHER PTHR11879:SF11 1 396 1.9E-247 T 22-04-2016 TOLA_RS07480 9cb8efdd6151a236a14490eb4e82ea31 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 243 256 - T 22-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 TOLA_RS07480 9cb8efdd6151a236a14490eb4e82ea31 396 Pfam PF00155 Aminotransferase class I and II 26 391 8.9E-86 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TOLA_RS07480 9cb8efdd6151a236a14490eb4e82ea31 396 Gene3D G3DSA:3.40.640.10 46 315 1.8E-105 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS10370 fc02de1e1b8208c8e757b6feb0e8dfa4 182 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 169 1.0E-73 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TOLA_RS10370 fc02de1e1b8208c8e757b6feb0e8dfa4 182 Gene3D G3DSA:2.60.120.10 1 178 5.7E-83 T 22-04-2016 IPR014710 RmlC-like jelly roll fold TOLA_RS10370 fc02de1e1b8208c8e757b6feb0e8dfa4 182 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 3.5E-76 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TOLA_RS10370 fc02de1e1b8208c8e757b6feb0e8dfa4 182 PANTHER PTHR21047 1 178 1.9E-77 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TOLA_RS10370 fc02de1e1b8208c8e757b6feb0e8dfa4 182 SUPERFAMILY SSF51182 1 179 3.56E-78 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS10370 fc02de1e1b8208c8e757b6feb0e8dfa4 182 PANTHER PTHR21047:SF2 1 178 1.9E-77 T 22-04-2016 TOLA_RS10370 fc02de1e1b8208c8e757b6feb0e8dfa4 182 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 178 3.7E-81 T 22-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TOLA_RS00695 f735038b8ad8eb1b11e73549a4b2802d 308 Pfam PF13432 Tetratricopeptide repeat 205 258 8.3E-9 T 22-04-2016 TOLA_RS00695 f735038b8ad8eb1b11e73549a4b2802d 308 Gene3D G3DSA:1.25.40.10 208 290 2.2E-15 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS00695 f735038b8ad8eb1b11e73549a4b2802d 308 SUPERFAMILY SSF48452 210 291 1.21E-12 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS00695 f735038b8ad8eb1b11e73549a4b2802d 308 Pfam PF13529 Peptidase_C39 like family 37 149 4.2E-11 T 22-04-2016 TOLA_RS10195 25d6b95c4df953e803654f068cbcc5a0 343 PANTHER PTHR21712 6 343 5.1E-111 T 22-04-2016 TOLA_RS10195 25d6b95c4df953e803654f068cbcc5a0 343 Gene3D G3DSA:1.10.1610.10 4 68 3.9E-24 T 22-04-2016 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 TOLA_RS10195 25d6b95c4df953e803654f068cbcc5a0 343 Pfam PF02277 Phosphoribosyltransferase 7 341 1.4E-133 T 22-04-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 TOLA_RS10195 25d6b95c4df953e803654f068cbcc5a0 343 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 12 341 4.3E-131 T 22-04-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 TOLA_RS10195 25d6b95c4df953e803654f068cbcc5a0 343 PANTHER PTHR21712:SF4 6 343 5.1E-111 T 22-04-2016 TOLA_RS10195 25d6b95c4df953e803654f068cbcc5a0 343 SUPERFAMILY SSF52733 5 342 1.14E-115 T 22-04-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 TOLA_RS10195 25d6b95c4df953e803654f068cbcc5a0 343 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 9 343 35.217 T 22-04-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 TOLA_RS10195 25d6b95c4df953e803654f068cbcc5a0 343 Gene3D G3DSA:3.40.50.10210 69 324 1.4E-109 T 22-04-2016 TOLA_RS00520 eddf838ec25c45e3182e1068242b0aa7 212 Pfam PF00297 Ribosomal protein L3 101 183 4.6E-12 T 22-04-2016 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00520 eddf838ec25c45e3182e1068242b0aa7 212 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 210 39.772 T 22-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00520 eddf838ec25c45e3182e1068242b0aa7 212 SUPERFAMILY SSF50447 1 211 8.03E-81 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain TOLA_RS00520 eddf838ec25c45e3182e1068242b0aa7 212 PANTHER PTHR11229 1 211 7.2E-116 T 22-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00520 eddf838ec25c45e3182e1068242b0aa7 212 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 207 3.2E-89 T 22-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00520 eddf838ec25c45e3182e1068242b0aa7 212 ProSitePatterns PS00474 Ribosomal protein L3 signature. 104 127 - T 22-04-2016 IPR019926 Ribosomal protein L3, conserved site TOLA_RS00520 eddf838ec25c45e3182e1068242b0aa7 212 Gene3D G3DSA:4.10.960.10 78 160 2.3E-33 T 22-04-2016 TOLA_RS00520 eddf838ec25c45e3182e1068242b0aa7 212 Gene3D G3DSA:2.40.30.10 4 33 3.1E-8 T 22-04-2016 TOLA_RS00520 eddf838ec25c45e3182e1068242b0aa7 212 Gene3D G3DSA:2.40.30.10 161 210 3.1E-8 T 22-04-2016 TOLA_RS07110 b8f5c7545b65d1148b2d07e0c1eef928 216 SUPERFAMILY SSF56784 4 210 4.14E-51 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS07110 b8f5c7545b65d1148b2d07e0c1eef928 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 185 2.4E-31 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS07110 b8f5c7545b65d1148b2d07e0c1eef928 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 73 186 3.8E-11 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS07110 b8f5c7545b65d1148b2d07e0c1eef928 216 PANTHER PTHR18901:SF34 1 210 1.7E-60 T 22-04-2016 TOLA_RS07110 b8f5c7545b65d1148b2d07e0c1eef928 216 Gene3D G3DSA:3.40.50.1000 1 16 4.3E-38 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS07110 b8f5c7545b65d1148b2d07e0c1eef928 216 Gene3D G3DSA:3.40.50.1000 90 212 4.3E-38 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS07110 b8f5c7545b65d1148b2d07e0c1eef928 216 Gene3D G3DSA:1.10.150.240 17 84 1.1E-25 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 TOLA_RS07110 b8f5c7545b65d1148b2d07e0c1eef928 216 PANTHER PTHR18901 1 210 1.7E-60 T 22-04-2016 TOLA_RS01220 f21a6bb17487734e00c148fc7dc1bf4f 215 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 39 48 - T 22-04-2016 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562|UniPathway: UPA00227|UniPathway: UPA00856 TOLA_RS01220 f21a6bb17487734e00c148fc7dc1bf4f 215 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 10 209 1.3E-80 T 22-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TOLA_RS01220 f21a6bb17487734e00c148fc7dc1bf4f 215 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 127 140 - T 22-04-2016 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TOLA_RS01220 f21a6bb17487734e00c148fc7dc1bf4f 215 Pfam PF01081 KDPG and KHG aldolase 12 202 1.2E-75 T 22-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TOLA_RS01220 f21a6bb17487734e00c148fc7dc1bf4f 215 PANTHER PTHR30246 1 215 4.1E-106 T 22-04-2016 TOLA_RS01220 f21a6bb17487734e00c148fc7dc1bf4f 215 PANTHER PTHR30246:SF0 1 215 4.1E-106 T 22-04-2016 TOLA_RS01220 f21a6bb17487734e00c148fc7dc1bf4f 215 SUPERFAMILY SSF51569 4 211 8.24E-71 T 22-04-2016 TOLA_RS01220 f21a6bb17487734e00c148fc7dc1bf4f 215 Gene3D G3DSA:3.20.20.70 6 214 5.3E-80 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS04140 6fa45efd2a1cd52954481a1d1f6ad626 154 PANTHER PTHR39563 2 152 8.6E-93 T 22-04-2016 TOLA_RS04140 6fa45efd2a1cd52954481a1d1f6ad626 154 SUPERFAMILY SSF53271 3 145 2.96E-27 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS04140 6fa45efd2a1cd52954481a1d1f6ad626 154 Gene3D G3DSA:3.40.50.2020 1 145 3.0E-41 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS04140 6fa45efd2a1cd52954481a1d1f6ad626 154 Pfam PF00156 Phosphoribosyl transferase domain 15 141 5.0E-16 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 TOLA_RS04140 6fa45efd2a1cd52954481a1d1f6ad626 154 Hamap MF_01903 Xanthine phosphoribosyltransferase [gpt]. 1 153 39.665 T 22-04-2016 IPR023747 Xanthine-guanine phosphoribosyltransferase GO:0000310 KEGG: 00230+2.4.2.22|UniPathway: UPA00602 TOLA_RS03025 dffad13cd252e90fbe2822c62f689392 410 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 168 394 1.8E-70 T 22-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 TOLA_RS03025 dffad13cd252e90fbe2822c62f689392 410 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 7 394 7.0E-140 T 22-04-2016 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 TOLA_RS03025 dffad13cd252e90fbe2822c62f689392 410 SUPERFAMILY SSF51690 120 393 6.08E-81 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 TOLA_RS03025 dffad13cd252e90fbe2822c62f689392 410 PIRSF PIRSF000484 1 396 3.7E-62 T 22-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 TOLA_RS03025 dffad13cd252e90fbe2822c62f689392 410 PANTHER PTHR11098 7 395 6.2E-149 T 22-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 TOLA_RS03025 dffad13cd252e90fbe2822c62f689392 410 SUPERFAMILY SSF54675 7 136 4.71E-36 T 22-04-2016 TOLA_RS03025 dffad13cd252e90fbe2822c62f689392 410 PANTHER PTHR11098:SF16 7 395 6.2E-149 T 22-04-2016 TOLA_RS03025 dffad13cd252e90fbe2822c62f689392 410 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 3 396 43.453 T 22-04-2016 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 TOLA_RS03025 dffad13cd252e90fbe2822c62f689392 410 Gene3D G3DSA:3.20.140.10 6 393 5.7E-130 T 22-04-2016 TOLA_RS03285 9f14c504260f97a43eac052608e48e7c 468 Pfam PF06097 Bacterial protein of unknown function (DUF945) 162 460 6.6E-17 T 22-04-2016 IPR010352 Protein of unknown function DUF945 TOLA_RS13560 43611015c23e760704ac31085b17f7da 162 SUPERFAMILY SSF55083 1 151 2.09E-40 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS13560 43611015c23e760704ac31085b17f7da 162 PANTHER PTHR20941 1 162 3.8E-56 T 22-04-2016 TOLA_RS13560 43611015c23e760704ac31085b17f7da 162 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 129 1.1E-24 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS13560 43611015c23e760704ac31085b17f7da 162 PANTHER PTHR20941:SF12 1 162 3.8E-56 T 22-04-2016 TOLA_RS13560 43611015c23e760704ac31085b17f7da 162 Gene3D G3DSA:3.30.70.560 3 150 6.7E-38 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS13560 43611015c23e760704ac31085b17f7da 162 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 129 1.5E-24 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS02625 970e1fdf7425723adc4c7a1c72b41dfa 143 SMART SM00450 40 138 2.4E-22 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS02625 970e1fdf7425723adc4c7a1c72b41dfa 143 PANTHER PTHR12231:SF138 48 143 2.0E-32 T 22-04-2016 TOLA_RS02625 970e1fdf7425723adc4c7a1c72b41dfa 143 Gene3D G3DSA:3.40.250.10 24 141 9.1E-32 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS02625 970e1fdf7425723adc4c7a1c72b41dfa 143 SUPERFAMILY SSF52821 15 140 7.6E-34 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS02625 970e1fdf7425723adc4c7a1c72b41dfa 143 PANTHER PTHR12231 48 143 2.0E-32 T 22-04-2016 TOLA_RS02625 970e1fdf7425723adc4c7a1c72b41dfa 143 Pfam PF00581 Rhodanese-like domain 44 134 8.7E-20 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS00640 e6b151c9721c3fe19f4a42c9994907f0 206 Gene3D G3DSA:1.10.1050.10 1 102 1.1E-42 T 22-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 TOLA_RS00640 e6b151c9721c3fe19f4a42c9994907f0 206 SMART SM00363 96 160 9.2E-20 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS00640 e6b151c9721c3fe19f4a42c9994907f0 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 3.3E-31 T 22-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 TOLA_RS00640 e6b151c9721c3fe19f4a42c9994907f0 206 PANTHER PTHR11831:SF4 1 206 2.7E-96 T 22-04-2016 TOLA_RS00640 e6b151c9721c3fe19f4a42c9994907f0 206 Gene3D G3DSA:3.10.290.10 103 190 8.5E-33 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS00640 e6b151c9721c3fe19f4a42c9994907f0 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 22-04-2016 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 TOLA_RS00640 e6b151c9721c3fe19f4a42c9994907f0 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 36.544 T 22-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TOLA_RS00640 e6b151c9721c3fe19f4a42c9994907f0 206 PANTHER PTHR11831 1 206 2.7E-96 T 22-04-2016 IPR022801 Ribosomal protein S4/S9 TOLA_RS00640 e6b151c9721c3fe19f4a42c9994907f0 206 Pfam PF01479 S4 domain 97 143 5.2E-19 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS00640 e6b151c9721c3fe19f4a42c9994907f0 206 SMART SM01390 3 95 1.4E-50 T 22-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 TOLA_RS00640 e6b151c9721c3fe19f4a42c9994907f0 206 SUPERFAMILY SSF55174 3 206 1.31E-73 T 22-04-2016 TOLA_RS00640 e6b151c9721c3fe19f4a42c9994907f0 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 1.7E-86 T 22-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TOLA_RS13850 55d5e61cdd6ceab3f61e9b3e7a3779f9 247 Gene3D G3DSA:1.10.10.200 1 78 6.5E-34 T 22-04-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like TOLA_RS13850 55d5e61cdd6ceab3f61e9b3e7a3779f9 247 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 236 1.2E-100 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like TOLA_RS13850 55d5e61cdd6ceab3f61e9b3e7a3779f9 247 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 238 36.299 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like TOLA_RS13850 55d5e61cdd6ceab3f61e9b3e7a3779f9 247 SUPERFAMILY SSF75625 3 244 7.46E-96 T 22-04-2016 IPR029072 YebC-like TOLA_RS13850 55d5e61cdd6ceab3f61e9b3e7a3779f9 247 Gene3D G3DSA:3.30.1270.10 83 134 7.2E-40 T 22-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 TOLA_RS13850 55d5e61cdd6ceab3f61e9b3e7a3779f9 247 Gene3D G3DSA:3.30.1270.10 211 246 7.2E-40 T 22-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 TOLA_RS13850 55d5e61cdd6ceab3f61e9b3e7a3779f9 247 Gene3D G3DSA:3.30.70.980 135 204 1.8E-29 T 22-04-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 TOLA_RS13850 55d5e61cdd6ceab3f61e9b3e7a3779f9 247 Pfam PF01709 Transcriptional regulator 5 235 2.4E-92 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like TOLA_RS13850 55d5e61cdd6ceab3f61e9b3e7a3779f9 247 PANTHER PTHR12532 1 240 6.3E-118 T 22-04-2016 IPR002876 Transcriptional regulator TACO1-like TOLA_RS08375 5702af8abca2eb258d191b3cb5a89997 306 Gene3D G3DSA:3.40.190.10 98 183 1.1E-19 T 22-04-2016 TOLA_RS08375 5702af8abca2eb258d191b3cb5a89997 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 4.9E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS08375 5702af8abca2eb258d191b3cb5a89997 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 4.9E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS08375 5702af8abca2eb258d191b3cb5a89997 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 4.9E-7 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS08375 5702af8abca2eb258d191b3cb5a89997 306 Gene3D G3DSA:1.10.10.10 10 89 1.2E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08375 5702af8abca2eb258d191b3cb5a89997 306 SUPERFAMILY SSF53850 96 302 4.16E-42 T 22-04-2016 TOLA_RS08375 5702af8abca2eb258d191b3cb5a89997 306 PANTHER PTHR30537:SF5 2 304 9.2E-101 T 22-04-2016 TOLA_RS08375 5702af8abca2eb258d191b3cb5a89997 306 SUPERFAMILY SSF46785 13 91 5.96E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08375 5702af8abca2eb258d191b3cb5a89997 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 69 2.1E-19 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS08375 5702af8abca2eb258d191b3cb5a89997 306 Gene3D G3DSA:3.40.190.10 184 267 1.2E-4 T 22-04-2016 TOLA_RS08375 5702af8abca2eb258d191b3cb5a89997 306 Pfam PF03466 LysR substrate binding domain 95 299 4.1E-41 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS08375 5702af8abca2eb258d191b3cb5a89997 306 PANTHER PTHR30537 2 304 9.2E-101 T 22-04-2016 TOLA_RS09695 466cc16b02c2c141ee5beeace35ba3c5 68 Gene3D G3DSA:1.10.260.40 1 67 1.7E-14 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS09695 466cc16b02c2c141ee5beeace35ba3c5 68 SUPERFAMILY SSF47413 2 66 4.64E-9 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS09695 466cc16b02c2c141ee5beeace35ba3c5 68 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 5 67 4.0E-17 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 PANTHER PTHR21060 2 400 2.2E-260 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 PANTHER PTHR21060:SF15 2 400 2.2E-260 T 22-04-2016 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 Gene3D G3DSA:3.30.420.40 206 396 2.0E-75 T 22-04-2016 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 PRINTS PR00471 Acetate kinase family signature 378 390 1.0E-46 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 PRINTS PR00471 Acetate kinase family signature 300 313 1.0E-46 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 PRINTS PR00471 Acetate kinase family signature 174 187 1.0E-46 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 PRINTS PR00471 Acetate kinase family signature 204 225 1.0E-46 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 PRINTS PR00471 Acetate kinase family signature 6 17 1.0E-46 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 PRINTS PR00471 Acetate kinase family signature 323 339 1.0E-46 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 SUPERFAMILY SSF53067 158 397 5.68E-85 T 22-04-2016 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 6 17 - T 22-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 204 221 - T 22-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 Pfam PF00871 Acetokinase family 6 391 3.3E-167 T 22-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 Hamap MF_00020 Acetate kinase [ackA]. 1 400 184.652 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 TIGRFAM TIGR00016 ackA: acetate kinase 1 397 1.2E-173 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 PIRSF PIRSF000722 2 400 3.8E-148 T 22-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 SUPERFAMILY SSF53067 4 197 2.52E-65 T 22-04-2016 TOLA_RS09635 6d91ff66a736e5cff9cd28b8022878f0 400 Gene3D G3DSA:3.30.420.40 116 205 3.4E-9 T 22-04-2016 TOLA_RS08100 5ee34241ce200ec93c6197d2ec2441d7 115 Pfam PF08870 Domain of unknown function (DUF1832) 5 108 4.3E-32 T 22-04-2016 IPR014969 DNA sulphur modification protein DndE TOLA_RS08100 5ee34241ce200ec93c6197d2ec2441d7 115 TIGRFAM TIGR03184 DNA_S_dndE: DNA sulfur modification protein DndE 6 104 2.9E-26 T 22-04-2016 IPR014969 DNA sulphur modification protein DndE TOLA_RS12370 f5a3dd450bd3dbf7e3032cca57617415 196 Pfam PF01464 Transglycosylase SLT domain 37 158 5.7E-7 T 22-04-2016 IPR008258 Transglycosylase SLT domain 1 TOLA_RS12370 f5a3dd450bd3dbf7e3032cca57617415 196 SUPERFAMILY SSF53955 104 181 1.32E-16 T 22-04-2016 IPR023346 Lysozyme-like domain TOLA_RS12370 f5a3dd450bd3dbf7e3032cca57617415 196 SUPERFAMILY SSF53955 34 76 1.32E-16 T 22-04-2016 IPR023346 Lysozyme-like domain TOLA_RS12370 f5a3dd450bd3dbf7e3032cca57617415 196 Gene3D G3DSA:1.10.530.10 35 181 4.9E-13 T 22-04-2016 TOLA_RS03720 df377d457a2a4dc756f9ed3b9ee30819 228 Pfam PF10979 Protein of unknown function (DUF2786) 5 43 9.7E-16 T 22-04-2016 IPR024498 Domain of unknown function DUF2786 TOLA_RS03720 df377d457a2a4dc756f9ed3b9ee30819 228 PIRSF PIRSF028111 1 228 9.5E-73 T 22-04-2016 IPR016868 Bacteriophage B3, Orf5 TOLA_RS05000 d00d8ecbb17bea69d639407c98b23268 298 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 10 298 1.2E-117 T 22-04-2016 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 TOLA_RS05000 d00d8ecbb17bea69d639407c98b23268 298 Gene3D G3DSA:1.10.443.10 114 289 2.0E-54 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS05000 d00d8ecbb17bea69d639407c98b23268 298 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 5 298 62.485 T 22-04-2016 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 TOLA_RS05000 d00d8ecbb17bea69d639407c98b23268 298 PANTHER PTHR30349 8 298 6.0E-115 T 22-04-2016 TOLA_RS05000 d00d8ecbb17bea69d639407c98b23268 298 SUPERFAMILY SSF56349 109 296 1.62E-54 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TOLA_RS05000 d00d8ecbb17bea69d639407c98b23268 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 91 5.0E-23 T 22-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TOLA_RS05000 d00d8ecbb17bea69d639407c98b23268 298 Pfam PF00589 Phage integrase family 114 284 3.1E-52 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS05000 d00d8ecbb17bea69d639407c98b23268 298 PANTHER PTHR30349:SF5 8 298 6.0E-115 T 22-04-2016 TOLA_RS05000 d00d8ecbb17bea69d639407c98b23268 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 298 31.089 T 22-04-2016 IPR023009 Tyrosine recombinase XerC/XerD TOLA_RS05000 d00d8ecbb17bea69d639407c98b23268 298 Gene3D G3DSA:1.10.150.130 7 100 6.4E-27 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal TOLA_RS05000 d00d8ecbb17bea69d639407c98b23268 298 SUPERFAMILY SSF47823 5 101 9.81E-36 T 22-04-2016 IPR010998 Integrase, Lambda-type, N-terminal TOLA_RS11500 b6b1e25b8e324170862344ccbc433a86 160 ProSitePatterns PS01317 SsrA-binding protein. 32 44 - T 22-04-2016 IPR020081 SsrA-binding protein, conserved site TOLA_RS11500 b6b1e25b8e324170862344ccbc433a86 160 Gene3D G3DSA:2.40.280.10 13 133 1.9E-49 T 22-04-2016 IPR023620 Small protein B TOLA_RS11500 b6b1e25b8e324170862344ccbc433a86 160 SUPERFAMILY SSF74982 8 138 9.68E-51 T 22-04-2016 IPR023620 Small protein B TOLA_RS11500 b6b1e25b8e324170862344ccbc433a86 160 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 14 138 1.0E-44 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 TOLA_RS11500 b6b1e25b8e324170862344ccbc433a86 160 TIGRFAM TIGR00086 smpB: SsrA-binding protein 14 156 1.5E-55 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 TOLA_RS11500 b6b1e25b8e324170862344ccbc433a86 160 Hamap MF_00023 SsrA-binding protein [smpB]. 1 160 73.779 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 TOLA_RS11500 b6b1e25b8e324170862344ccbc433a86 160 PANTHER PTHR30308:SF2 1 160 2.5E-84 T 22-04-2016 TOLA_RS11500 b6b1e25b8e324170862344ccbc433a86 160 Pfam PF01668 SmpB protein 13 75 2.9E-28 T 22-04-2016 IPR000037 SsrA-binding protein GO:0003723 TOLA_RS11500 b6b1e25b8e324170862344ccbc433a86 160 PANTHER PTHR30308 1 160 2.5E-84 T 22-04-2016 TOLA_RS07620 a7485d745f7671ba60c621e63db5138a 366 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 345 1.0E-65 T 22-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 TOLA_RS07620 a7485d745f7671ba60c621e63db5138a 366 SUPERFAMILY SSF51395 5 352 1.7E-108 T 22-04-2016 TOLA_RS07620 a7485d745f7671ba60c621e63db5138a 366 Gene3D G3DSA:3.20.20.70 2 348 1.8E-116 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS07620 a7485d745f7671ba60c621e63db5138a 366 PANTHER PTHR22893 7 350 9.4E-137 T 22-04-2016 TOLA_RS07620 a7485d745f7671ba60c621e63db5138a 366 PANTHER PTHR22893:SF7 7 350 9.4E-137 T 22-04-2016 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 SUPERFAMILY SSF50447 165 288 2.91E-28 T 22-04-2016 IPR009000 Translation protein, beta-barrel domain TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 22-04-2016 IPR031157 Tr-type G domain, conserved site TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 Pfam PF00679 Elongation factor G C-terminus 399 483 4.3E-20 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 176 1.5E-19 T 22-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 Gene3D G3DSA:2.40.30.10 193 289 2.0E-22 T 22-04-2016 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 SMART SM00838 398 486 0.0033 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 Pfam PF00009 Elongation factor Tu GTP binding domain 2 181 1.7E-54 T 22-04-2016 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 SUPERFAMILY SSF54980 399 493 1.49E-25 T 22-04-2016 IPR009022 Elongation factor G, III-V domain TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 SUPERFAMILY SSF52540 2 205 7.28E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 PANTHER PTHR23115 397 595 1.1E-273 T 22-04-2016 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 PANTHER PTHR23115 2 373 1.1E-273 T 22-04-2016 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 PRINTS PR00315 GTP-binding elongation factor signature 90 101 4.0E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 PRINTS PR00315 GTP-binding elongation factor signature 74 84 4.0E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 PRINTS PR00315 GTP-binding elongation factor signature 6 19 4.0E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 PRINTS PR00315 GTP-binding elongation factor signature 49 57 4.0E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 PRINTS PR00315 GTP-binding elongation factor signature 126 135 4.0E-14 T 22-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 Gene3D G3DSA:3.30.70.870 291 369 5.2E-26 T 22-04-2016 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 Pfam PF03144 Elongation factor Tu domain 2 205 275 6.0E-10 T 22-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 PANTHER PTHR23115:SF175 397 595 1.1E-273 T 22-04-2016 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 PANTHER PTHR23115:SF175 2 373 1.1E-273 T 22-04-2016 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 Gene3D G3DSA:3.30.70.240 401 489 3.9E-21 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 Gene3D G3DSA:3.40.50.300 2 192 1.2E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 TIGRFAM TIGR01393 lepA: elongation factor 4 2 594 1.4E-303 T 22-04-2016 IPR006297 Elongation factor 4 GO:0005525 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 307.492 T 22-04-2016 IPR006297 Elongation factor 4 GO:0005525 TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 Pfam PF06421 GTP-binding protein LepA C-terminus 487 592 3.2E-49 T 22-04-2016 IPR013842 GTP-binding protein LepA, C-terminal TOLA_RS04350 5a0cfbae08b7a9f1366dd22e8b3012e2 598 SUPERFAMILY SSF54980 292 370 1.44E-18 T 22-04-2016 IPR009022 Elongation factor G, III-V domain TOLA_RS08540 f9f81e716d170bdc3da768ba3fe70900 214 Gene3D G3DSA:3.40.50.10230 3 212 2.9E-78 T 22-04-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 TOLA_RS08540 f9f81e716d170bdc3da768ba3fe70900 214 Pfam PF02570 Precorrin-8X methylmutase 10 208 2.0E-72 T 22-04-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 TOLA_RS08540 f9f81e716d170bdc3da768ba3fe70900 214 SUPERFAMILY SSF63965 10 212 5.49E-67 T 22-04-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 TOLA_RS08540 f9f81e716d170bdc3da768ba3fe70900 214 PANTHER PTHR32439 1 213 4.4E-70 T 22-04-2016 TOLA_RS12375 b1588f6f1eb610b3d234b4d495ec4f75 181 Pfam PF11072 Protein of unknown function (DUF2859) 33 179 8.6E-58 T 22-04-2016 IPR021300 Integrating conjugative element protein, PFL4695 TOLA_RS12375 b1588f6f1eb610b3d234b4d495ec4f75 181 TIGRFAM TIGR03765 ICE_PFL_4695: integrating conjugative element protein, PFL_4695 family 77 181 1.2E-44 T 22-04-2016 IPR021300 Integrating conjugative element protein, PFL4695 TOLA_RS03605 88a3a2932a5093e30c5d96fa68e4225a 164 Pfam PF13673 Acetyltransferase (GNAT) domain 84 148 6.1E-9 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS03605 88a3a2932a5093e30c5d96fa68e4225a 164 PANTHER PTHR36449 1 163 1.6E-56 T 22-04-2016 TOLA_RS03605 88a3a2932a5093e30c5d96fa68e4225a 164 Gene3D G3DSA:3.40.630.30 35 149 1.7E-17 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS03605 88a3a2932a5093e30c5d96fa68e4225a 164 SUPERFAMILY SSF55729 15 146 2.02E-13 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS06960 dede45ac871dcf7125398994b1ddee52 184 TIGRFAM TIGR02563 cas_Csy4: CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST 3 184 2.4E-50 T 22-04-2016 IPR013396 CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST GO:0004519|GO:0043571 TOLA_RS06960 dede45ac871dcf7125398994b1ddee52 184 Pfam PF09618 CRISPR-associated protein (Cas_Csy4) 4 184 8.0E-59 T 22-04-2016 IPR013396 CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST GO:0004519|GO:0043571 TOLA_RS05945 6edd462e93ad2e0edc682a88c35157c8 257 ProDom PD315856 ORF119 CPE0798 YOXB 21 221 3.0E-62 T 22-04-2016 IPR020530 Uncharacterised protein family, YoxB TOLA_RS00930 41853d71c59bf7b6a4c6a9e5d17003a8 297 PIRSF PIRSF037505 2 297 2.3E-11 T 22-04-2016 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 UniPathway: UPA00051 TOLA_RS00930 41853d71c59bf7b6a4c6a9e5d17003a8 297 Pfam PF02574 Homocysteine S-methyltransferase 6 294 4.6E-60 T 22-04-2016 IPR003726 Homocysteine-binding domain TOLA_RS00930 41853d71c59bf7b6a4c6a9e5d17003a8 297 PANTHER PTHR11103 2 294 1.1E-50 T 22-04-2016 TOLA_RS00930 41853d71c59bf7b6a4c6a9e5d17003a8 297 PANTHER PTHR11103:SF7 2 294 1.1E-50 T 22-04-2016 TOLA_RS00930 41853d71c59bf7b6a4c6a9e5d17003a8 297 Gene3D G3DSA:3.20.20.330 3 297 2.3E-77 T 22-04-2016 IPR003726 Homocysteine-binding domain TOLA_RS00930 41853d71c59bf7b6a4c6a9e5d17003a8 297 SUPERFAMILY SSF82282 3 297 3.01E-82 T 22-04-2016 IPR003726 Homocysteine-binding domain TOLA_RS04690 5d41df1f23b3ecc510c27e002ecaabda 192 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 190 36.755 T 22-04-2016 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478|UniPathway: UPA00041 TOLA_RS04690 5d41df1f23b3ecc510c27e002ecaabda 192 PANTHER PTHR30390:SF6 2 190 5.3E-85 T 22-04-2016 TOLA_RS04690 5d41df1f23b3ecc510c27e002ecaabda 192 SUPERFAMILY SSF53697 1 189 9.22E-52 T 22-04-2016 TOLA_RS04690 5d41df1f23b3ecc510c27e002ecaabda 192 TIGRFAM TIGR00441 gmhA: phosphoheptose isomerase 35 187 1.3E-76 T 22-04-2016 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478|UniPathway: UPA00041 TOLA_RS04690 5d41df1f23b3ecc510c27e002ecaabda 192 Gene3D G3DSA:3.40.50.10490 1 190 1.6E-61 T 22-04-2016 TOLA_RS04690 5d41df1f23b3ecc510c27e002ecaabda 192 PANTHER PTHR30390 2 190 5.3E-85 T 22-04-2016 TOLA_RS04690 5d41df1f23b3ecc510c27e002ecaabda 192 Pfam PF13580 SIS domain 24 146 5.1E-30 T 22-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 TOLA_RS13525 9ed69771e0a0e6ed36da9b47c50a464a 425 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 163 171 - T 22-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TOLA_RS13525 9ed69771e0a0e6ed36da9b47c50a464a 425 Gene3D G3DSA:3.40.50.300 9 222 1.3E-67 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13525 9ed69771e0a0e6ed36da9b47c50a464a 425 PANTHER PTHR24031 1 390 2.8E-252 T 22-04-2016 TOLA_RS13525 9ed69771e0a0e6ed36da9b47c50a464a 425 Gene3D G3DSA:3.40.50.300 223 380 3.3E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13525 9ed69771e0a0e6ed36da9b47c50a464a 425 Pfam PF00270 DEAD/DEAH box helicase 33 207 7.8E-43 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS13525 9ed69771e0a0e6ed36da9b47c50a464a 425 PANTHER PTHR24031:SF173 1 390 2.8E-252 T 22-04-2016 TOLA_RS13525 9ed69771e0a0e6ed36da9b47c50a464a 425 SMART SM00490 270 351 2.6E-33 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS13525 9ed69771e0a0e6ed36da9b47c50a464a 425 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 8 389 49.691 T 22-04-2016 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 TOLA_RS13525 9ed69771e0a0e6ed36da9b47c50a464a 425 Pfam PF00271 Helicase conserved C-terminal domain 243 351 2.2E-29 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS13525 9ed69771e0a0e6ed36da9b47c50a464a 425 SUPERFAMILY SSF52540 84 363 2.82E-70 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13525 9ed69771e0a0e6ed36da9b47c50a464a 425 SMART SM00487 28 234 2.4E-50 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS10580 2ef90c9e39b269001963941bf9ceae13 296 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 1 283 17.807 T 22-04-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 UniPathway: UPA00834 TOLA_RS10580 2ef90c9e39b269001963941bf9ceae13 296 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 56 78 - T 22-04-2016 IPR030470 UbiA prenyltransferase conserved site TOLA_RS10580 2ef90c9e39b269001963941bf9ceae13 296 Pfam PF01040 UbiA prenyltransferase family 18 267 1.8E-58 T 22-04-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 TOLA_RS10580 2ef90c9e39b269001963941bf9ceae13 296 PANTHER PTHR11048:SF20 1 286 1.6E-140 T 22-04-2016 TOLA_RS10580 2ef90c9e39b269001963941bf9ceae13 296 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 3 281 3.2E-89 T 22-04-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 UniPathway: UPA00834 TOLA_RS10580 2ef90c9e39b269001963941bf9ceae13 296 PANTHER PTHR11048 1 286 1.6E-140 T 22-04-2016 TOLA_RS06905 75bec0b51757e2f3714a47d42e6d61b0 381 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 135 376 1.5E-66 T 22-04-2016 IPR003453 ABC transport permease subunit MlaE, Proteobacteria TOLA_RS06905 75bec0b51757e2f3714a47d42e6d61b0 381 Pfam PF02405 Permease MlaE 166 374 5.4E-68 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 TOLA_RS06905 75bec0b51757e2f3714a47d42e6d61b0 381 PANTHER PTHR30188:SF3 38 381 9.3E-142 T 22-04-2016 TOLA_RS06905 75bec0b51757e2f3714a47d42e6d61b0 381 PANTHER PTHR30188 38 381 9.3E-142 T 22-04-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 TOLA_RS00480 067f2546f366ca931180850a649d9de8 195 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 4 188 5.0E-31 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TOLA_RS00480 067f2546f366ca931180850a649d9de8 195 PANTHER PTHR33508 1 194 3.0E-79 T 22-04-2016 TOLA_RS00480 067f2546f366ca931180850a649d9de8 195 PANTHER PTHR33508:SF4 1 194 3.0E-79 T 22-04-2016 TOLA_RS00480 067f2546f366ca931180850a649d9de8 195 Pfam PF01914 MarC family integral membrane protein 3 191 4.2E-52 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 Pfam PF00717 Peptidase S24-like 86 165 9.9E-22 T 22-04-2016 IPR019759 Peptidase S24/S26A/S26B TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 Gene3D G3DSA:2.10.109.10 239 280 3.9E-55 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 Gene3D G3DSA:2.10.109.10 77 153 3.9E-55 T 22-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 65 279 4.2E-49 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 SUPERFAMILY SSF51306 78 304 2.88E-72 T 22-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 Pfam PF10502 Signal peptidase, peptidase S26 235 277 6.0E-7 T 22-04-2016 IPR019533 Peptidase S26 TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 ProSitePatterns PS00760 Signal peptidases I lysine active site. 146 158 - T 22-04-2016 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 ProSitePatterns PS00501 Signal peptidases I serine active site. 89 96 - T 22-04-2016 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: REACT_15380 TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 Gene3D G3DSA:2.170.230.10 154 238 3.5E-23 T 22-04-2016 IPR019766 Peptidase S26A, all-beta subdomain TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 80 96 8.4E-26 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 239 258 8.4E-26 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 144 156 8.4E-26 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 PANTHER PTHR12383 221 283 2.7E-98 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 PANTHER PTHR12383 3 190 2.7E-98 T 22-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 PANTHER PTHR12383:SF27 221 283 2.7E-98 T 22-04-2016 TOLA_RS04355 a09f99d34949d9d15fc63d2d0a9309eb 306 PANTHER PTHR12383:SF27 3 190 2.7E-98 T 22-04-2016 TOLA_RS11435 9b59e511a9c31425a2a327203afe4331 280 Gene3D G3DSA:3.20.20.20 12 274 7.4E-108 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 TOLA_RS11435 9b59e511a9c31425a2a327203afe4331 280 PANTHER PTHR20941 1 276 5.0E-120 T 22-04-2016 TOLA_RS11435 9b59e511a9c31425a2a327203afe4331 280 SUPERFAMILY SSF51717 8 274 7.98E-102 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 TOLA_RS11435 9b59e511a9c31425a2a327203afe4331 280 Pfam PF00809 Pterin binding enzyme 18 256 1.6E-87 T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 TOLA_RS11435 9b59e511a9c31425a2a327203afe4331 280 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 17 268 2.1E-102 T 22-04-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614|UniPathway: UPA00077 TOLA_RS11435 9b59e511a9c31425a2a327203afe4331 280 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 17 32 - T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 TOLA_RS11435 9b59e511a9c31425a2a327203afe4331 280 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 51 64 - T 22-04-2016 IPR000489 Pterin-binding domain GO:0042558 TOLA_RS11435 9b59e511a9c31425a2a327203afe4331 280 PANTHER PTHR20941:SF1 1 276 5.0E-120 T 22-04-2016 TOLA_RS03825 01132c89a8bcd83510991472d000befb 139 Pfam PF07030 Protein of unknown function (DUF1320) 3 123 4.2E-38 T 22-04-2016 IPR009752 Bacteriophage Mu, Gp36 TOLA_RS03410 8aede41426891743fd8745c09c1833c1 401 SUPERFAMILY SSF53383 3 375 3.32E-105 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS03410 8aede41426891743fd8745c09c1833c1 401 PANTHER PTHR11601:SF45 2 383 1.1E-163 T 22-04-2016 TOLA_RS03410 8aede41426891743fd8745c09c1833c1 401 Gene3D G3DSA:3.40.640.10 16 247 4.7E-88 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS03410 8aede41426891743fd8745c09c1833c1 401 Gene3D G3DSA:3.90.1150.10 248 370 2.7E-45 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS03410 8aede41426891743fd8745c09c1833c1 401 TIGRFAM TIGR03402 FeS_nifS: cysteine desulfurase NifS 4 382 2.5E-186 T 22-04-2016 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal GO:0006520|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 TOLA_RS03410 8aede41426891743fd8745c09c1833c1 401 Pfam PF00266 Aminotransferase class-V 4 365 1.1E-91 T 22-04-2016 IPR000192 Aminotransferase class V domain TOLA_RS03410 8aede41426891743fd8745c09c1833c1 401 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 22-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TOLA_RS03410 8aede41426891743fd8745c09c1833c1 401 PANTHER PTHR11601 2 383 1.1E-163 T 22-04-2016 TOLA_RS03410 8aede41426891743fd8745c09c1833c1 401 PIRSF PIRSF005572 1 380 1.7E-125 T 22-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 TOLA_RS02645 4be379b922f30e8b3beb42d3998f230a 236 SUPERFAMILY SSF53271 48 231 3.93E-31 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS02645 4be379b922f30e8b3beb42d3998f230a 236 PANTHER PTHR11907 21 231 6.0E-50 T 22-04-2016 TOLA_RS02645 4be379b922f30e8b3beb42d3998f230a 236 Gene3D G3DSA:3.40.50.2020 59 232 3.9E-27 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS02645 4be379b922f30e8b3beb42d3998f230a 236 PANTHER PTHR11907:SF9 21 231 6.0E-50 T 22-04-2016 TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 8 388 1.4E-123 T 22-04-2016 IPR017687 Outer membrane protein assembly factor BamB TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 PANTHER PTHR32303:SF8 8 381 1.8E-110 T 22-04-2016 TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 Gene3D G3DSA:2.140.10.10 7 390 3.3E-72 T 22-04-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 SMART SM00564 249 280 30.0 T 22-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 SMART SM00564 328 359 1.3 T 22-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 SMART SM00564 112 144 2.3E-4 T 22-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 SMART SM00564 63 94 3.3E-6 T 22-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 SMART SM00564 288 318 210.0 T 22-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 SMART SM00564 153 184 1.3E-5 T 22-04-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 Pfam PF13360 PQQ-like domain 76 316 5.4E-50 T 22-04-2016 IPR002372 Pyrrolo-quinoline quinone repeat TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 SUPERFAMILY SSF50998 17 382 6.41E-82 T 22-04-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 PANTHER PTHR32303 8 381 1.8E-110 T 22-04-2016 TOLA_RS04570 8b5e1f4a2e02d7c28995f222444a4ccb 392 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 3 390 36.646 T 22-04-2016 IPR017687 Outer membrane protein assembly factor BamB TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 PANTHER PTHR32494 15 420 1.5E-162 T 22-04-2016 TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 PANTHER PTHR32494:SF5 15 420 1.5E-162 T 22-04-2016 TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 Pfam PF01546 Peptidase family M20/M25/M40 83 410 1.4E-23 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 30 409 3.2E-112 T 22-04-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 Gene3D G3DSA:3.40.630.10 355 412 5.9E-98 T 22-04-2016 TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 Gene3D G3DSA:3.40.630.10 11 231 5.9E-98 T 22-04-2016 TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 82 91 - T 22-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 Gene3D G3DSA:3.30.70.360 232 332 1.3E-34 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 PIRSF PIRSF001235 9 416 5.5E-127 T 22-04-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 SUPERFAMILY SSF55031 219 332 3.66E-25 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 Pfam PF07687 Peptidase dimerisation domain 218 315 1.3E-4 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 SUPERFAMILY SSF53187 27 229 1.74E-73 T 22-04-2016 TOLA_RS09940 a00767d6044f292277ab2b1ce3be8bf3 422 SUPERFAMILY SSF53187 340 412 1.74E-73 T 22-04-2016 TOLA_RS14215 009f9028a3ba6c7fdeac70e0d4b1d8c8 156 PANTHER PTHR11205 1 156 3.1E-96 T 22-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 TOLA_RS14215 009f9028a3ba6c7fdeac70e0d4b1d8c8 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 3.4E-67 T 22-04-2016 IPR023798 Ribosomal protein S7 domain TOLA_RS14215 009f9028a3ba6c7fdeac70e0d4b1d8c8 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 22-04-2016 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 TOLA_RS14215 009f9028a3ba6c7fdeac70e0d4b1d8c8 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 3.9E-71 T 22-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TOLA_RS14215 009f9028a3ba6c7fdeac70e0d4b1d8c8 156 SUPERFAMILY SSF47973 6 149 2.22E-60 T 22-04-2016 IPR023798 Ribosomal protein S7 domain TOLA_RS14215 009f9028a3ba6c7fdeac70e0d4b1d8c8 156 Gene3D G3DSA:1.10.455.10 8 156 9.2E-68 T 22-04-2016 IPR023798 Ribosomal protein S7 domain TOLA_RS14215 009f9028a3ba6c7fdeac70e0d4b1d8c8 156 PIRSF PIRSF002122 3 156 3.9E-63 T 22-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 TOLA_RS14215 009f9028a3ba6c7fdeac70e0d4b1d8c8 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.945 T 22-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TOLA_RS05220 e837452c0b771357b45ea0905ad6db8a 303 Gene3D G3DSA:1.10.3720.10 37 290 9.3E-55 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05220 e837452c0b771357b45ea0905ad6db8a 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 297 1.1E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05220 e837452c0b771357b45ea0905ad6db8a 303 SUPERFAMILY SSF161098 35 303 4.32E-59 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05220 e837452c0b771357b45ea0905ad6db8a 303 PANTHER PTHR32243 24 303 2.1E-71 T 22-04-2016 TOLA_RS06095 53a02faae3eab61586d877a1c148a304 566 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 4 561 1.9E-219 T 22-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TOLA_RS06095 53a02faae3eab61586d877a1c148a304 566 Pfam PF03814 Potassium-transporting ATPase A subunit 12 560 2.2E-224 T 22-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TOLA_RS06095 53a02faae3eab61586d877a1c148a304 566 PIRSF PIRSF001294 1 564 2.3E-218 T 22-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TOLA_RS06095 53a02faae3eab61586d877a1c148a304 566 PANTHER PTHR30607 2 566 1.4E-270 T 22-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TOLA_RS06095 53a02faae3eab61586d877a1c148a304 566 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 562 33.661 T 22-04-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 TOLA_RS12470 c902f7912ef9bc34cf4a80fbc79900f1 506 Pfam PF07916 TraG-like protein, N-terminal region 10 488 5.6E-103 T 22-04-2016 IPR012931 TraG-like, N-terminal TOLA_RS07910 5611103b171bd671b2534cd1548e57d1 135 Pfam PF00816 H-NS histone family 32 125 2.4E-19 T 22-04-2016 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 TOLA_RS07910 5611103b171bd671b2534cd1548e57d1 135 Gene3D G3DSA:4.10.430.10 89 133 2.9E-23 T 22-04-2016 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 TOLA_RS07910 5611103b171bd671b2534cd1548e57d1 135 PANTHER PTHR38097 2 134 4.7E-52 T 22-04-2016 TOLA_RS07910 5611103b171bd671b2534cd1548e57d1 135 Gene3D G3DSA:1.10.287.1050 1 58 2.1E-18 T 22-04-2016 IPR027454 Histone-like protein H-NS family, oligomerisation domain GO:0046983 TOLA_RS07910 5611103b171bd671b2534cd1548e57d1 135 SMART SM00528 85 132 2.1E-19 T 22-04-2016 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 TOLA_RS07910 5611103b171bd671b2534cd1548e57d1 135 SUPERFAMILY SSF81273 90 133 1.29E-11 T 22-04-2016 TOLA_RS07910 5611103b171bd671b2534cd1548e57d1 135 SUPERFAMILY SSF81273 2 58 3.53E-15 T 22-04-2016 TOLA_RS07910 5611103b171bd671b2534cd1548e57d1 135 PIRSF PIRSF002096 1 132 3.8E-51 T 22-04-2016 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 TOLA_RS07910 5611103b171bd671b2534cd1548e57d1 135 PANTHER PTHR38097:SF2 2 134 4.7E-52 T 22-04-2016 TOLA_RS11145 f6d1971fd0f78e98073574d44e888efd 329 Gene3D G3DSA:3.40.718.10 1 321 1.7E-116 T 22-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 TOLA_RS11145 f6d1971fd0f78e98073574d44e888efd 329 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 322 1.1E-100 T 22-04-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 TOLA_RS11145 f6d1971fd0f78e98073574d44e888efd 329 SUPERFAMILY SSF53659 1 321 7.81E-91 T 22-04-2016 TOLA_RS11145 f6d1971fd0f78e98073574d44e888efd 329 PIRSF PIRSF002465 1 328 8.8E-113 T 22-04-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 TOLA_RS11145 f6d1971fd0f78e98073574d44e888efd 329 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 329 125.5 T 22-04-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 TOLA_RS11145 f6d1971fd0f78e98073574d44e888efd 329 PANTHER PTHR30100 1 329 1.6E-111 T 22-04-2016 TOLA_RS11145 f6d1971fd0f78e98073574d44e888efd 329 Pfam PF02504 Fatty acid synthesis protein 1 314 1.4E-92 T 22-04-2016 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 UniPathway: UPA00085 TOLA_RS11145 f6d1971fd0f78e98073574d44e888efd 329 PANTHER PTHR30100:SF1 1 329 1.6E-111 T 22-04-2016 TOLA_RS10465 8463202c45e8cee4a252db94d26effea 230 PANTHER PTHR10010 1 225 2.2E-85 T 22-04-2016 TOLA_RS10465 8463202c45e8cee4a252db94d26effea 230 Gene3D G3DSA:1.20.58.220 124 226 1.1E-32 T 22-04-2016 TOLA_RS10465 8463202c45e8cee4a252db94d26effea 230 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 10 218 1.1E-71 T 22-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TOLA_RS10465 8463202c45e8cee4a252db94d26effea 230 PANTHER PTHR10010:SF14 1 225 2.2E-85 T 22-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TOLA_RS10465 8463202c45e8cee4a252db94d26effea 230 Gene3D G3DSA:1.20.58.220 6 112 4.9E-35 T 22-04-2016 TOLA_RS10465 8463202c45e8cee4a252db94d26effea 230 Pfam PF01895 PhoU domain 24 109 4.4E-19 T 22-04-2016 IPR026022 PhoU domain TOLA_RS10465 8463202c45e8cee4a252db94d26effea 230 Pfam PF01895 PhoU domain 124 208 7.6E-19 T 22-04-2016 IPR026022 PhoU domain TOLA_RS10465 8463202c45e8cee4a252db94d26effea 230 SUPERFAMILY SSF109755 10 226 7.95E-69 T 22-04-2016 TOLA_RS10465 8463202c45e8cee4a252db94d26effea 230 PIRSF PIRSF003107 4 223 1.2E-68 T 22-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TOLA_RS01065 06f4c3476ee144b520bde7b5616a55fe 585 PANTHER PTHR35370:SF4 3 585 1.5E-182 T 22-04-2016 TOLA_RS01065 06f4c3476ee144b520bde7b5616a55fe 585 Pfam PF05947 Type VI secretion system, ImpG, VasA, VC_A0110 5 583 3.4E-170 T 22-04-2016 IPR010272 Type VI secretion system, TssF-like TOLA_RS01065 06f4c3476ee144b520bde7b5616a55fe 585 PANTHER PTHR35370 3 585 1.5E-182 T 22-04-2016 TOLA_RS01065 06f4c3476ee144b520bde7b5616a55fe 585 PIRSF PIRSF028304 1 585 1.7E-160 T 22-04-2016 IPR010272 Type VI secretion system, TssF-like TOLA_RS01065 06f4c3476ee144b520bde7b5616a55fe 585 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 3 584 9.7E-166 T 22-04-2016 IPR010272 Type VI secretion system, TssF-like TOLA_RS02040 66a22473afb072cdc6e56ef89327b135 308 Pfam PF00005 ABC transporter 23 165 2.6E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS02040 66a22473afb072cdc6e56ef89327b135 308 PANTHER PTHR24220:SF0 289 296 2.9E-102 T 22-04-2016 TOLA_RS02040 66a22473afb072cdc6e56ef89327b135 308 PANTHER PTHR24220:SF0 9 227 2.9E-102 T 22-04-2016 TOLA_RS02040 66a22473afb072cdc6e56ef89327b135 308 SUPERFAMILY SSF52540 4 230 2.55E-65 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02040 66a22473afb072cdc6e56ef89327b135 308 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS02040 66a22473afb072cdc6e56ef89327b135 308 PANTHER PTHR24220 289 296 2.9E-102 T 22-04-2016 TOLA_RS02040 66a22473afb072cdc6e56ef89327b135 308 PANTHER PTHR24220 9 227 2.9E-102 T 22-04-2016 TOLA_RS02040 66a22473afb072cdc6e56ef89327b135 308 Gene3D G3DSA:3.40.50.300 3 232 1.6E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02040 66a22473afb072cdc6e56ef89327b135 308 SMART SM00382 32 211 1.4E-11 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS06200 d6ee945321624a6f2df302c95daf1c5d 277 TIGRFAM TIGR01334 modD: modD protein 5 272 8.2E-75 T 22-04-2016 IPR006242 Putative pyrophosphorylase ModD GO:0016763 KEGG: 00230+2.4.2.-|KEGG: 00514+2.4.2.- TOLA_RS06200 d6ee945321624a6f2df302c95daf1c5d 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 107 271 8.8E-29 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 TOLA_RS06200 d6ee945321624a6f2df302c95daf1c5d 277 SUPERFAMILY SSF51690 107 273 7.06E-38 T 22-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 TOLA_RS06200 d6ee945321624a6f2df302c95daf1c5d 277 Gene3D G3DSA:3.20.20.70 127 263 4.8E-35 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS06200 d6ee945321624a6f2df302c95daf1c5d 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 105 6.7E-20 T 22-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 TOLA_RS06200 d6ee945321624a6f2df302c95daf1c5d 277 PIRSF PIRSF006250 3 275 9.4E-56 T 22-04-2016 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD TOLA_RS06200 d6ee945321624a6f2df302c95daf1c5d 277 Gene3D G3DSA:3.90.1170.20 5 126 1.8E-27 T 22-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 TOLA_RS06200 d6ee945321624a6f2df302c95daf1c5d 277 PANTHER PTHR11948 1 266 1.6E-39 T 22-04-2016 TOLA_RS06200 d6ee945321624a6f2df302c95daf1c5d 277 PANTHER PTHR11948:SF1 1 266 1.6E-39 T 22-04-2016 TOLA_RS06200 d6ee945321624a6f2df302c95daf1c5d 277 SUPERFAMILY SSF54675 4 106 5.89E-20 T 22-04-2016 TOLA_RS08355 e6a956cc7345e78b6f7872d97bd37b4f 319 SUPERFAMILY SSF52833 42 160 4.28E-14 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS08355 e6a956cc7345e78b6f7872d97bd37b4f 319 PANTHER PTHR32419 6 314 3.3E-143 T 22-04-2016 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 TOLA_RS08355 e6a956cc7345e78b6f7872d97bd37b4f 319 Pfam PF13409 Glutathione S-transferase, N-terminal domain 62 157 1.7E-21 T 22-04-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TOLA_RS08355 e6a956cc7345e78b6f7872d97bd37b4f 319 PIRSF PIRSF015753 5 318 1.4E-115 T 22-04-2016 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 TOLA_RS08355 e6a956cc7345e78b6f7872d97bd37b4f 319 SUPERFAMILY SSF47616 168 298 7.24E-24 T 22-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like TOLA_RS08355 e6a956cc7345e78b6f7872d97bd37b4f 319 Gene3D G3DSA:3.40.30.10 43 177 3.3E-17 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS08355 e6a956cc7345e78b6f7872d97bd37b4f 319 Gene3D G3DSA:1.20.1050.10 178 289 5.3E-19 T 22-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like TOLA_RS08355 e6a956cc7345e78b6f7872d97bd37b4f 319 Pfam PF13410 Glutathione S-transferase, C-terminal domain 203 276 1.4E-11 T 22-04-2016 TOLA_RS08355 e6a956cc7345e78b6f7872d97bd37b4f 319 PANTHER PTHR32419:SF6 6 314 3.3E-143 T 22-04-2016 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 39 452 9.8E-159 T 22-04-2016 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 Pfam PF13180 PDZ domain 379 434 6.7E-9 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 Pfam PF13180 PDZ domain 277 357 5.7E-16 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 SMART SM00228 269 348 2.7E-13 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 SMART SM00228 373 446 3.8E-9 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 SUPERFAMILY SSF50156 217 243 2.53E-23 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 Gene3D G3DSA:2.30.42.10 387 452 7.6E-17 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 Gene3D G3DSA:2.30.42.10 268 361 8.2E-29 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 SUPERFAMILY SSF50156 283 361 2.53E-23 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 PANTHER PTHR22939:SF101 1 454 9.6E-180 T 22-04-2016 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 Gene3D G3DSA:2.40.10.10 155 267 2.2E-44 T 22-04-2016 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 PRINTS PR00834 HtrA/DegQ protease family signature 306 318 9.0E-57 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 PRINTS PR00834 HtrA/DegQ protease family signature 102 114 9.0E-57 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 PRINTS PR00834 HtrA/DegQ protease family signature 198 215 9.0E-57 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 PRINTS PR00834 HtrA/DegQ protease family signature 123 143 9.0E-57 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 PRINTS PR00834 HtrA/DegQ protease family signature 220 237 9.0E-57 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 PRINTS PR00834 HtrA/DegQ protease family signature 163 187 9.0E-57 T 22-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 SUPERFAMILY SSF50156 386 451 1.58E-14 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 SUPERFAMILY SSF50494 89 274 2.64E-64 T 22-04-2016 IPR009003 Peptidase S1, PA clan TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 SUPERFAMILY SSF50494 22 58 2.64E-64 T 22-04-2016 IPR009003 Peptidase S1, PA clan TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 PANTHER PTHR22939 1 454 9.6E-180 T 22-04-2016 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 Gene3D G3DSA:2.40.10.10 37 154 1.6E-34 T 22-04-2016 TOLA_RS15000 fe998e03ac41f0ef2c1e25db3675bee3 454 Pfam PF13365 Trypsin-like peptidase domain 92 227 3.1E-31 T 22-04-2016 TOLA_RS08225 82a6a39dd549af0f8333cfd77ae85bf7 207 PIRSF PIRSF005624 1 206 1.7E-50 T 22-04-2016 TOLA_RS08225 82a6a39dd549af0f8333cfd77ae85bf7 207 Hamap MF_01389 Urease accessory protein UreG [ureG]. 6 204 46.551 T 22-04-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 TOLA_RS08225 82a6a39dd549af0f8333cfd77ae85bf7 207 Gene3D G3DSA:3.40.50.300 8 197 2.4E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08225 82a6a39dd549af0f8333cfd77ae85bf7 207 SUPERFAMILY SSF52540 4 200 6.93E-36 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08225 82a6a39dd549af0f8333cfd77ae85bf7 207 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 8 200 2.0E-99 T 22-04-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 TOLA_RS08225 82a6a39dd549af0f8333cfd77ae85bf7 207 PANTHER PTHR31715 7 197 6.3E-121 T 22-04-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 TOLA_RS08225 82a6a39dd549af0f8333cfd77ae85bf7 207 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 10 179 5.4E-41 T 22-04-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain TOLA_RS09105 784bdab878028947c70efd5d3558d874 426 PANTHER PTHR11662:SF3 10 411 4.4E-115 T 22-04-2016 TOLA_RS09105 784bdab878028947c70efd5d3558d874 426 Gene3D G3DSA:1.20.1250.20 12 205 1.4E-42 T 22-04-2016 TOLA_RS09105 784bdab878028947c70efd5d3558d874 426 SUPERFAMILY SSF103473 5 413 3.79E-88 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS09105 784bdab878028947c70efd5d3558d874 426 Gene3D G3DSA:1.20.1250.20 224 412 2.7E-35 T 22-04-2016 TOLA_RS09105 784bdab878028947c70efd5d3558d874 426 Pfam PF07690 Major Facilitator Superfamily 18 375 1.4E-58 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS09105 784bdab878028947c70efd5d3558d874 426 PANTHER PTHR11662 10 411 4.4E-115 T 22-04-2016 TOLA_RS09105 784bdab878028947c70efd5d3558d874 426 PIRSF PIRSF002808 8 425 1.6E-36 T 22-04-2016 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 TOLA_RS12020 31ab15d603ec8736f0a4110353844f2a 277 SUPERFAMILY SSF46565 135 273 3.56E-28 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS12020 31ab15d603ec8736f0a4110353844f2a 277 Gene3D G3DSA:1.10.3680.10 21 214 1.2E-27 T 22-04-2016 IPR029024 TerB-like TOLA_RS12020 31ab15d603ec8736f0a4110353844f2a 277 Pfam PF05099 Tellurite resistance protein TerB 47 174 2.3E-12 T 22-04-2016 IPR007791 Co-chaperone DjlA, N-terminal TOLA_RS12020 31ab15d603ec8736f0a4110353844f2a 277 Gene3D G3DSA:1.10.287.110 215 272 2.6E-16 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS12020 31ab15d603ec8736f0a4110353844f2a 277 SMART SM00271 210 275 7.8E-18 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS12020 31ab15d603ec8736f0a4110353844f2a 277 Pfam PF00226 DnaJ domain 211 272 5.0E-12 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS12020 31ab15d603ec8736f0a4110353844f2a 277 PRINTS PR00625 DnaJ domain signature 231 246 1.8E-9 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS12020 31ab15d603ec8736f0a4110353844f2a 277 PRINTS PR00625 DnaJ domain signature 213 231 1.8E-9 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS12020 31ab15d603ec8736f0a4110353844f2a 277 PRINTS PR00625 DnaJ domain signature 255 275 1.8E-9 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS02065 b4f4d4fcc97e1a0166b3b8c72b85c848 273 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 14 259 38.686 T 22-04-2016 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 TOLA_RS02065 b4f4d4fcc97e1a0166b3b8c72b85c848 273 SUPERFAMILY SSF56300 15 270 3.94E-61 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS02065 b4f4d4fcc97e1a0166b3b8c72b85c848 273 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 204 259 8.0E-14 T 22-04-2016 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 TOLA_RS02065 b4f4d4fcc97e1a0166b3b8c72b85c848 273 PANTHER PTHR12905:SF7 50 273 2.1E-91 T 22-04-2016 TOLA_RS02065 b4f4d4fcc97e1a0166b3b8c72b85c848 273 PANTHER PTHR12905:SF7 5 34 2.1E-91 T 22-04-2016 TOLA_RS02065 b4f4d4fcc97e1a0166b3b8c72b85c848 273 PANTHER PTHR12905 5 34 2.1E-91 T 22-04-2016 TOLA_RS02065 b4f4d4fcc97e1a0166b3b8c72b85c848 273 Pfam PF00149 Calcineurin-like phosphoesterase 15 204 7.5E-18 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 TOLA_RS02065 b4f4d4fcc97e1a0166b3b8c72b85c848 273 PANTHER PTHR12905 50 273 2.1E-91 T 22-04-2016 TOLA_RS02065 b4f4d4fcc97e1a0166b3b8c72b85c848 273 Gene3D G3DSA:3.60.21.10 13 255 2.6E-41 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS15640 a317327ddc062a02164a9ed5585d752b 311 PANTHER PTHR10584:SF57 1 304 2.4E-147 T 22-04-2016 TOLA_RS15640 a317327ddc062a02164a9ed5585d752b 311 Gene3D G3DSA:3.40.1190.20 2 300 9.7E-73 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS15640 a317327ddc062a02164a9ed5585d752b 311 SUPERFAMILY SSF53613 3 302 3.9E-71 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS15640 a317327ddc062a02164a9ed5585d752b 311 PANTHER PTHR10584 1 304 2.4E-147 T 22-04-2016 TOLA_RS15640 a317327ddc062a02164a9ed5585d752b 311 Pfam PF00294 pfkB family carbohydrate kinase 5 303 4.3E-64 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB TOLA_RS15640 a317327ddc062a02164a9ed5585d752b 311 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 257 270 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TOLA_RS00560 0844bb910c65c050c520980cbbdca7d6 63 SUPERFAMILY SSF46561 1 61 1.44E-22 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00560 0844bb910c65c050c520980cbbdca7d6 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 18.599 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00560 0844bb910c65c050c520980cbbdca7d6 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 2.7E-23 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00560 0844bb910c65c050c520980cbbdca7d6 63 Pfam PF00831 Ribosomal L29 protein 4 60 3.4E-24 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00560 0844bb910c65c050c520980cbbdca7d6 63 Gene3D G3DSA:1.10.287.310 1 60 3.4E-28 T 22-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00560 0844bb910c65c050c520980cbbdca7d6 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 22-04-2016 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00560 0844bb910c65c050c520980cbbdca7d6 63 PANTHER PTHR10916 1 63 4.3E-28 T 22-04-2016 TOLA_RS11265 cd5852ed150c1dda1e7e6523d8d7df20 322 Gene3D G3DSA:2.40.160.10 21 322 1.7E-26 T 22-04-2016 IPR023614 Porin domain TOLA_RS11265 cd5852ed150c1dda1e7e6523d8d7df20 322 SUPERFAMILY SSF56935 30 322 1.68E-28 T 22-04-2016 TOLA_RS16245 cfb3099931a94da673dc23ce7f2e2fda 119 Pfam PF00825 Ribonuclease P 7 113 1.4E-31 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TOLA_RS16245 cfb3099931a94da673dc23ce7f2e2fda 119 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 7 116 18.317 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TOLA_RS16245 cfb3099931a94da673dc23ce7f2e2fda 119 SUPERFAMILY SSF54211 6 117 4.8E-31 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS16245 cfb3099931a94da673dc23ce7f2e2fda 119 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 17 106 5.0E-23 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TOLA_RS16245 cfb3099931a94da673dc23ce7f2e2fda 119 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 7 114 3.4E-30 T 22-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TOLA_RS16245 cfb3099931a94da673dc23ce7f2e2fda 119 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 57 71 - T 22-04-2016 IPR020539 Ribonuclease P, conserved site GO:0004526 TOLA_RS16245 cfb3099931a94da673dc23ce7f2e2fda 119 PANTHER PTHR33992 4 116 5.4E-38 T 22-04-2016 TOLA_RS16245 cfb3099931a94da673dc23ce7f2e2fda 119 Gene3D G3DSA:3.30.230.10 6 117 1.5E-34 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS10700 db62cc38756725c6e6302b1371c43246 449 PANTHER PTHR22939 198 449 1.9E-82 T 22-04-2016 TOLA_RS10700 db62cc38756725c6e6302b1371c43246 449 SMART SM00228 210 279 1.1E-9 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS10700 db62cc38756725c6e6302b1371c43246 449 SMART SM00228 115 186 4.7E-4 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS10700 db62cc38756725c6e6302b1371c43246 449 PANTHER PTHR22939:SF78 198 449 1.9E-82 T 22-04-2016 TOLA_RS10700 db62cc38756725c6e6302b1371c43246 449 Pfam PF13180 PDZ domain 225 286 2.0E-7 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS10700 db62cc38756725c6e6302b1371c43246 449 Gene3D G3DSA:2.30.42.10 201 289 9.0E-18 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS10700 db62cc38756725c6e6302b1371c43246 449 Gene3D G3DSA:2.30.42.10 96 184 5.1E-14 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS10700 db62cc38756725c6e6302b1371c43246 449 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 5 448 2.6E-134 T 22-04-2016 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 TOLA_RS10700 db62cc38756725c6e6302b1371c43246 449 Pfam PF02163 Peptidase family M50 11 437 4.5E-84 T 22-04-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 TOLA_RS10700 db62cc38756725c6e6302b1371c43246 449 SUPERFAMILY SSF50156 88 187 8.68E-15 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS10700 db62cc38756725c6e6302b1371c43246 449 SUPERFAMILY SSF50156 209 291 1.04E-15 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS01205 e10f8d785c91689b09773e313f7f5246 332 PANTHER PTHR30146:SF37 5 332 2.1E-174 T 22-04-2016 TOLA_RS01205 e10f8d785c91689b09773e313f7f5246 332 Gene3D G3DSA:3.40.50.2300 62 171 1.8E-33 T 22-04-2016 TOLA_RS01205 e10f8d785c91689b09773e313f7f5246 332 Gene3D G3DSA:3.40.50.2300 172 331 1.6E-31 T 22-04-2016 TOLA_RS01205 e10f8d785c91689b09773e313f7f5246 332 SUPERFAMILY SSF53822 62 320 5.1E-48 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS01205 e10f8d785c91689b09773e313f7f5246 332 SMART SM00354 5 75 4.6E-26 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS01205 e10f8d785c91689b09773e313f7f5246 332 Gene3D G3DSA:1.10.260.40 4 59 7.7E-18 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS01205 e10f8d785c91689b09773e313f7f5246 332 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 7.2E-18 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS01205 e10f8d785c91689b09773e313f7f5246 332 PANTHER PTHR30146 5 332 2.1E-174 T 22-04-2016 TOLA_RS01205 e10f8d785c91689b09773e313f7f5246 332 SUPERFAMILY SSF47413 4 63 5.57E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS01205 e10f8d785c91689b09773e313f7f5246 332 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS01205 e10f8d785c91689b09773e313f7f5246 332 Pfam PF13377 Periplasmic binding protein-like domain 181 331 1.2E-21 T 22-04-2016 TOLA_RS04855 04711775db1d19bd4a0dffcc968c0d04 206 PANTHER PTHR17490 1 205 2.7E-92 T 22-04-2016 TOLA_RS04855 04711775db1d19bd4a0dffcc968c0d04 206 PANTHER PTHR17490:SF7 1 205 2.7E-92 T 22-04-2016 TOLA_RS04855 04711775db1d19bd4a0dffcc968c0d04 206 SUPERFAMILY SSF55821 1 203 1.04E-61 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TOLA_RS04855 04711775db1d19bd4a0dffcc968c0d04 206 Gene3D G3DSA:3.90.870.10 2 202 4.8E-62 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TOLA_RS04855 04711775db1d19bd4a0dffcc968c0d04 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 4.1E-68 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 TOLA_RS04855 04711775db1d19bd4a0dffcc968c0d04 206 Pfam PF01300 Telomere recombination 23 198 1.1E-43 T 22-04-2016 IPR006070 YrdC-like domain GO:0003725 TOLA_RS09955 7d2a563e443aff30678a655822c0bd0c 539 PANTHER PTHR11686 10 533 3.8E-132 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 TOLA_RS09955 7d2a563e443aff30678a655822c0bd0c 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 31 56 2.3E-16 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 TOLA_RS09955 7d2a563e443aff30678a655822c0bd0c 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 366 384 2.3E-16 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 TOLA_RS09955 7d2a563e443aff30678a655822c0bd0c 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 251 270 2.3E-16 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 TOLA_RS09955 7d2a563e443aff30678a655822c0bd0c 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 102 120 2.3E-16 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 TOLA_RS09955 7d2a563e443aff30678a655822c0bd0c 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 342 360 2.3E-16 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 TOLA_RS09955 7d2a563e443aff30678a655822c0bd0c 539 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 222 238 2.3E-16 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 TOLA_RS09955 7d2a563e443aff30678a655822c0bd0c 539 PANTHER PTHR11686:SF8 10 533 3.8E-132 T 22-04-2016 TOLA_RS09955 7d2a563e443aff30678a655822c0bd0c 539 Pfam PF01019 Gamma-glutamyltranspeptidase 24 523 1.4E-111 T 22-04-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 TOLA_RS09955 7d2a563e443aff30678a655822c0bd0c 539 SUPERFAMILY SSF56235 7 526 5.75E-132 T 22-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TOLA_RS10960 a5d0b053ab45d0cbd94a7bbc95fa06b7 499 PANTHER PTHR24220:SF516 9 381 1.6E-185 T 22-04-2016 TOLA_RS10960 a5d0b053ab45d0cbd94a7bbc95fa06b7 499 PANTHER PTHR24220 9 381 1.6E-185 T 22-04-2016 TOLA_RS10960 a5d0b053ab45d0cbd94a7bbc95fa06b7 499 Gene3D G3DSA:3.40.50.300 6 226 5.4E-61 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10960 a5d0b053ab45d0cbd94a7bbc95fa06b7 499 SUPERFAMILY SSF52540 6 224 3.8E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10960 a5d0b053ab45d0cbd94a7bbc95fa06b7 499 SMART SM00382 32 235 2.5E-8 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS10960 a5d0b053ab45d0cbd94a7bbc95fa06b7 499 SMART SM00382 281 476 0.002 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS10960 a5d0b053ab45d0cbd94a7bbc95fa06b7 499 Gene3D G3DSA:3.40.50.300 274 485 7.4E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10960 a5d0b053ab45d0cbd94a7bbc95fa06b7 499 SUPERFAMILY SSF52540 257 478 1.78E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10960 a5d0b053ab45d0cbd94a7bbc95fa06b7 499 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS10960 a5d0b053ab45d0cbd94a7bbc95fa06b7 499 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS10960 a5d0b053ab45d0cbd94a7bbc95fa06b7 499 Pfam PF00005 ABC transporter 274 427 3.9E-18 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS10960 a5d0b053ab45d0cbd94a7bbc95fa06b7 499 Pfam PF00005 ABC transporter 23 172 3.5E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS05110 e39b496e47647f4faba9a3d6569a90a6 409 SUPERFAMILY SSF161098 166 395 4.32E-21 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05110 e39b496e47647f4faba9a3d6569a90a6 409 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 244 392 8.3E-7 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05110 e39b496e47647f4faba9a3d6569a90a6 409 SUPERFAMILY SSF161098 40 140 6.28E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05110 e39b496e47647f4faba9a3d6569a90a6 409 Gene3D G3DSA:1.10.3720.10 14 144 1.1E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05110 e39b496e47647f4faba9a3d6569a90a6 409 Gene3D G3DSA:1.10.3720.10 168 397 4.1E-15 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05110 e39b496e47647f4faba9a3d6569a90a6 409 PANTHER PTHR30183 10 407 7.6E-89 T 22-04-2016 TOLA_RS05110 e39b496e47647f4faba9a3d6569a90a6 409 PANTHER PTHR30183:SF6 10 407 7.6E-89 T 22-04-2016 TOLA_RS00160 9e23d6880f38b4b61d727a91c96439d2 361 Pfam PF13439 Glycosyltransferase Family 4 25 176 1.0E-14 T 22-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain TOLA_RS00160 9e23d6880f38b4b61d727a91c96439d2 361 SUPERFAMILY SSF53756 19 324 3.14E-48 T 22-04-2016 TOLA_RS00160 9e23d6880f38b4b61d727a91c96439d2 361 Pfam PF00534 Glycosyl transferases group 1 189 328 3.7E-15 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 TOLA_RS00160 9e23d6880f38b4b61d727a91c96439d2 361 PANTHER PTHR12526 24 99 3.3E-29 T 22-04-2016 TOLA_RS00160 9e23d6880f38b4b61d727a91c96439d2 361 PANTHER PTHR12526 121 323 3.3E-29 T 22-04-2016 TOLA_RS00160 9e23d6880f38b4b61d727a91c96439d2 361 Gene3D G3DSA:3.40.50.2000 160 325 2.4E-20 T 22-04-2016 TOLA_RS03050 3b0f83515d6b33d179fffbcf8bdf90b6 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 5.7E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS03050 3b0f83515d6b33d179fffbcf8bdf90b6 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 5.7E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS03050 3b0f83515d6b33d179fffbcf8bdf90b6 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 9.7E-13 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS03050 3b0f83515d6b33d179fffbcf8bdf90b6 222 PANTHER PTHR30055 2 179 6.7E-20 T 22-04-2016 TOLA_RS03050 3b0f83515d6b33d179fffbcf8bdf90b6 222 SUPERFAMILY SSF46689 6 84 1.49E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS03050 3b0f83515d6b33d179fffbcf8bdf90b6 222 Gene3D G3DSA:1.10.10.60 9 55 6.3E-20 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS03050 3b0f83515d6b33d179fffbcf8bdf90b6 222 Pfam PF09209 Domain of unknown function (DUF1956) 95 217 3.5E-20 T 22-04-2016 IPR015292 Transcription regulator YbiH, C-terminal TOLA_RS03050 3b0f83515d6b33d179fffbcf8bdf90b6 222 Gene3D G3DSA:1.10.357.10 56 218 2.8E-45 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 TOLA_RS03050 3b0f83515d6b33d179fffbcf8bdf90b6 222 SUPERFAMILY SSF48498 87 217 1.07E-20 T 22-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 PANTHER PTHR11458 1 335 1.6E-188 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 PIRSF PIRSF001415 3 336 4.8E-148 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 SUPERFAMILY SSF51569 7 335 2.05E-144 T 22-04-2016 TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 307 326 4.1E-57 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 129 143 4.1E-57 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 160 179 4.1E-57 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 277 292 4.1E-57 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 252 268 4.1E-57 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 198 217 4.1E-57 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 Pfam PF00490 Delta-aminolevulinic acid dehydratase 12 332 6.5E-140 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 SMART SM01004 9 333 4.8E-241 T 22-04-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 252 264 - T 22-04-2016 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS01745 bf8a4e0d504af67958d027fe0c340c71 336 Gene3D G3DSA:3.20.20.70 7 335 2.9E-151 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS06005 e2393eadc62ccbc6054b1b22e661013a 401 SMART SM00922 163 269 2.2E-7 T 22-04-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TOLA_RS06005 e2393eadc62ccbc6054b1b22e661013a 401 Gene3D G3DSA:3.30.390.10 3 162 1.0E-42 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TOLA_RS06005 e2393eadc62ccbc6054b1b22e661013a 401 PANTHER PTHR13794:SF59 25 401 1.3E-296 T 22-04-2016 TOLA_RS06005 e2393eadc62ccbc6054b1b22e661013a 401 Pfam PF13378 Enolase C-terminal domain-like 185 392 1.1E-36 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS06005 e2393eadc62ccbc6054b1b22e661013a 401 Hamap MF_01288 L-rhamnonate dehydratase [rhmD]. 1 401 78.656 T 22-04-2016 IPR023444 L-rhamnonate dehydratase GO:0050032 KEGG: 00051+4.2.1.90|MetaCyc: PWY-6713|MetaCyc: PWY-6714 TOLA_RS06005 e2393eadc62ccbc6054b1b22e661013a 401 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 67 157 3.1E-7 T 22-04-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TOLA_RS06005 e2393eadc62ccbc6054b1b22e661013a 401 SUPERFAMILY SSF54826 41 158 8.61E-23 T 22-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TOLA_RS06005 e2393eadc62ccbc6054b1b22e661013a 401 SUPERFAMILY SSF51604 145 398 5.11E-55 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS06005 e2393eadc62ccbc6054b1b22e661013a 401 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 132 157 - T 22-04-2016 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 TOLA_RS06005 e2393eadc62ccbc6054b1b22e661013a 401 PANTHER PTHR13794 25 401 1.3E-296 T 22-04-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 TOLA_RS06005 e2393eadc62ccbc6054b1b22e661013a 401 Gene3D G3DSA:3.20.20.120 163 390 8.2E-56 T 22-04-2016 IPR029065 Enolase C-terminal domain-like TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 399 410 - T 22-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 Gene3D G3DSA:3.20.20.60 466 771 9.4E-103 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 Pfam PF00391 PEP-utilising enzyme, mobile domain 369 440 7.2E-26 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 679 697 - T 22-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 466 770 2.6E-59 T 22-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 SUPERFAMILY SSF56059 2 369 1.65E-104 T 22-04-2016 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 2 772 0.0 T 22-04-2016 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 SUPERFAMILY SSF51621 452 771 6.28E-96 T 22-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 Gene3D G3DSA:3.30.1490.20 2 180 7.9E-64 T 22-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 SUPERFAMILY SSF52009 334 452 3.79E-34 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 6 332 4.9E-119 T 22-04-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 Gene3D G3DSA:3.50.30.10 359 458 2.9E-35 T 22-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 PANTHER PTHR22931 270 772 0.0 T 22-04-2016 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 PANTHER PTHR22931 1 254 0.0 T 22-04-2016 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 Gene3D G3DSA:3.30.470.20 182 335 7.4E-62 T 22-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 PANTHER PTHR22931:SF7 270 772 0.0 T 22-04-2016 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 PANTHER PTHR22931:SF7 1 254 0.0 T 22-04-2016 TOLA_RS06730 d33d5b0986227a0455da0bd1d498113e 772 PIRSF PIRSF000854 1 772 0.0 T 22-04-2016 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|UniPathway: UPA00138 TOLA_RS04405 d5618e56c14d4f7d9d37bc85a753cf54 174 PANTHER PTHR19384 141 172 5.3E-88 T 22-04-2016 TOLA_RS04405 d5618e56c14d4f7d9d37bc85a753cf54 174 PANTHER PTHR19384 1 120 5.3E-88 T 22-04-2016 TOLA_RS04405 d5618e56c14d4f7d9d37bc85a753cf54 174 PIRSF PIRSF038996 1 172 5.7E-67 T 22-04-2016 IPR010086 Flavodoxin, long chain GO:0010181 TOLA_RS04405 d5618e56c14d4f7d9d37bc85a753cf54 174 TIGRFAM TIGR01752 flav_long: flavodoxin 4 168 5.2E-70 T 22-04-2016 IPR010086 Flavodoxin, long chain GO:0010181 TOLA_RS04405 d5618e56c14d4f7d9d37bc85a753cf54 174 Gene3D G3DSA:3.40.50.360 1 169 1.2E-61 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS04405 d5618e56c14d4f7d9d37bc85a753cf54 174 SUPERFAMILY SSF52218 4 170 2.99E-52 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS04405 d5618e56c14d4f7d9d37bc85a753cf54 174 Pfam PF00258 Flavodoxin 6 160 4.5E-30 T 22-04-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 TOLA_RS04405 d5618e56c14d4f7d9d37bc85a753cf54 174 PANTHER PTHR19384:SF77 141 172 5.3E-88 T 22-04-2016 TOLA_RS04405 d5618e56c14d4f7d9d37bc85a753cf54 174 PANTHER PTHR19384:SF77 1 120 5.3E-88 T 22-04-2016 TOLA_RS04405 d5618e56c14d4f7d9d37bc85a753cf54 174 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 22-04-2016 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 SUPERFAMILY SSF53335 137 429 5.63E-70 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 Gene3D G3DSA:1.10.940.10 2 146 1.2E-40 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 PANTHER PTHR22807:SF30 35 429 5.4E-120 T 22-04-2016 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 219 233 1.3E-29 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 365 381 1.3E-29 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 248 258 1.3E-29 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 412 429 1.3E-29 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 315 327 1.3E-29 T 22-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 Pfam PF01029 NusB family 1 123 6.8E-23 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 SUPERFAMILY SSF48013 1 146 5.1E-34 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 4 430 4.7E-142 T 22-04-2016 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 PANTHER PTHR22807 35 429 5.4E-120 T 22-04-2016 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 Pfam PF01189 16S rRNA methyltransferase RsmB/F 237 427 4.0E-71 T 22-04-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 Gene3D G3DSA:3.40.50.150 229 429 4.3E-57 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 314 325 - T 22-04-2016 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS00780 d5298efe212da4987831a1e6a1503bc1 433 Gene3D G3DSA:3.30.70.1170 170 227 1.4E-22 T 22-04-2016 TOLA_RS10665 25d313f99311099f38b30fcb4bfe8c48 197 Gene3D G3DSA:3.30.420.10 11 152 2.9E-49 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS10665 25d313f99311099f38b30fcb4bfe8c48 197 Pfam PF01351 Ribonuclease HII 13 189 1.8E-42 T 22-04-2016 IPR024567 Ribonuclease HII/HIII domain TOLA_RS10665 25d313f99311099f38b30fcb4bfe8c48 197 SUPERFAMILY SSF53098 4 194 5.92E-71 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS10665 25d313f99311099f38b30fcb4bfe8c48 197 PANTHER PTHR10954 1 195 7.6E-85 T 22-04-2016 IPR001352 Ribonuclease HII/HIII GO:0003723|GO:0004523 TOLA_RS10665 25d313f99311099f38b30fcb4bfe8c48 197 Hamap MF_00052_B Ribonuclease HII [rnhB]. 11 190 39.047 T 22-04-2016 IPR022898 Ribonuclease HII GO:0004523 TOLA_RS00805 a7b892dbdd01025e8fde512e1f5a0285 157 PANTHER PTHR38692:SF1 1 157 4.7E-71 T 22-04-2016 TOLA_RS00805 a7b892dbdd01025e8fde512e1f5a0285 157 PANTHER PTHR38692 1 157 4.7E-71 T 22-04-2016 TOLA_RS00805 a7b892dbdd01025e8fde512e1f5a0285 157 Pfam PF04361 Protein of unknown function (DUF494) 1 153 3.6E-58 T 22-04-2016 IPR007456 Smg TOLA_RS00805 a7b892dbdd01025e8fde512e1f5a0285 157 Hamap MF_00598 Protein Smg [smg]. 1 157 30.553 T 22-04-2016 IPR007456 Smg TOLA_RS16385 5e4b0b1fb3e2882ac7c78c8454914336 178 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS16385 5e4b0b1fb3e2882ac7c78c8454914336 178 SUPERFAMILY SSF54523 8 147 6.12E-15 T 22-04-2016 TOLA_RS16385 5e4b0b1fb3e2882ac7c78c8454914336 178 Pfam PF12019 Type II transport protein GspH 43 152 1.9E-10 T 22-04-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 TOLA_RS16385 5e4b0b1fb3e2882ac7c78c8454914336 178 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 27 1.1E-4 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS16385 5e4b0b1fb3e2882ac7c78c8454914336 178 Pfam PF13633 Prokaryotic N-terminal methylation site 6 31 3.3E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS14390 59e82edc9fdc2d74dc31ce96ae3e3f57 170 PANTHER PTHR35603:SF1 1 166 3.3E-23 T 22-04-2016 TOLA_RS14390 59e82edc9fdc2d74dc31ce96ae3e3f57 170 PANTHER PTHR35603 1 166 3.3E-23 T 22-04-2016 TOLA_RS14390 59e82edc9fdc2d74dc31ce96ae3e3f57 170 Pfam PF05433 Glycine zipper 2TM domain 70 111 1.3E-6 T 22-04-2016 IPR008816 Glycine zipper 2TM domain GO:0019867 TOLA_RS08945 33515903ba4b67aa65e065f3ff794752 336 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 14 336 36.703 T 22-04-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS08945 33515903ba4b67aa65e065f3ff794752 336 Gene3D G3DSA:3.20.20.70 14 304 9.6E-71 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS08945 33515903ba4b67aa65e065f3ff794752 336 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 14 336 1.2E-101 T 22-04-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS08945 33515903ba4b67aa65e065f3ff794752 336 PANTHER PTHR22960 5 292 4.0E-119 T 22-04-2016 TOLA_RS08945 33515903ba4b67aa65e065f3ff794752 336 SUPERFAMILY SSF102114 16 285 2.75E-70 T 22-04-2016 TOLA_RS08945 33515903ba4b67aa65e065f3ff794752 336 Pfam PF06463 Molybdenum Cofactor Synthesis C 193 319 8.8E-36 T 22-04-2016 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS08945 33515903ba4b67aa65e065f3ff794752 336 SMART SM00729 23 229 1.1E-7 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TOLA_RS08945 33515903ba4b67aa65e065f3ff794752 336 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 29 40 - T 22-04-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 TOLA_RS08945 33515903ba4b67aa65e065f3ff794752 336 Pfam PF13353 4Fe-4S single cluster domain 30 132 8.9E-9 T 22-04-2016 TOLA_RS08945 33515903ba4b67aa65e065f3ff794752 336 Pfam PF04055 Radical SAM superfamily 28 187 8.6E-28 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS11645 5097662dd290b276bdcce042b1e6fabf 178 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 3 168 19.537 T 22-04-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TOLA_RS11645 5097662dd290b276bdcce042b1e6fabf 178 PANTHER PTHR35561 1 170 3.4E-35 T 22-04-2016 TOLA_RS11645 5097662dd290b276bdcce042b1e6fabf 178 Gene3D G3DSA:3.90.1140.10 4 173 4.7E-39 T 22-04-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase TOLA_RS11645 5097662dd290b276bdcce042b1e6fabf 178 PANTHER PTHR35561:SF1 1 170 3.4E-35 T 22-04-2016 TOLA_RS11645 5097662dd290b276bdcce042b1e6fabf 178 Pfam PF13563 2'-5' RNA ligase superfamily 25 129 2.8E-12 T 22-04-2016 TOLA_RS11645 5097662dd290b276bdcce042b1e6fabf 178 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 4 168 2.0E-32 T 22-04-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TOLA_RS11645 5097662dd290b276bdcce042b1e6fabf 178 SUPERFAMILY SSF55144 4 169 8.72E-36 T 22-04-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase TOLA_RS04880 6edb98e713d3be69f69506fc0c9c15d2 459 PANTHER PTHR37957 166 309 4.7E-14 T 22-04-2016 TOLA_RS04880 6edb98e713d3be69f69506fc0c9c15d2 459 Pfam PF13449 Esterase-like activity of phytase 54 397 2.0E-51 T 22-04-2016 IPR027372 Phytase-like domain TOLA_RS00580 ae9d04b569c22e496a09d7f39c8d667d 179 Gene3D G3DSA:3.30.1440.10 2 179 3.8E-80 T 22-04-2016 IPR022803 Ribosomal protein L5 domain TOLA_RS00580 ae9d04b569c22e496a09d7f39c8d667d 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 22-04-2016 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00580 ae9d04b569c22e496a09d7f39c8d667d 179 Pfam PF00281 Ribosomal protein L5 24 80 1.6E-28 T 22-04-2016 IPR031310 Ribosomal protein L5, N-terminal TOLA_RS00580 ae9d04b569c22e496a09d7f39c8d667d 179 PIRSF PIRSF002161 1 179 1.1E-66 T 22-04-2016 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00580 ae9d04b569c22e496a09d7f39c8d667d 179 PANTHER PTHR11994 1 178 1.2E-100 T 22-04-2016 TOLA_RS00580 ae9d04b569c22e496a09d7f39c8d667d 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 44.682 T 22-04-2016 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00580 ae9d04b569c22e496a09d7f39c8d667d 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 1.5E-41 T 22-04-2016 IPR031309 Ribosomal protein L5, C-terminal TOLA_RS00580 ae9d04b569c22e496a09d7f39c8d667d 179 SUPERFAMILY SSF55282 4 179 4.47E-79 T 22-04-2016 IPR022803 Ribosomal protein L5 domain TOLA_RS07725 5d516dd38075f4caa7577be7bf6f1b04 346 SUPERFAMILY SSF46689 294 344 2.6E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS07725 5d516dd38075f4caa7577be7bf6f1b04 346 Pfam PF12833 Helix-turn-helix domain 266 343 1.2E-14 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS07725 5d516dd38075f4caa7577be7bf6f1b04 346 Gene3D G3DSA:1.10.10.60 294 344 3.1E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS07725 5d516dd38075f4caa7577be7bf6f1b04 346 SMART SM00342 259 341 1.7E-15 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS07725 5d516dd38075f4caa7577be7bf6f1b04 346 PANTHER PTHR11019 245 345 5.0E-14 T 22-04-2016 TOLA_RS01435 d7263702d731ca24ae918058e5427b99 258 Gene3D G3DSA:3.90.550.10 14 188 2.7E-22 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS01435 d7263702d731ca24ae918058e5427b99 258 PANTHER PTHR10859:SF49 13 243 1.2E-63 T 22-04-2016 TOLA_RS01435 d7263702d731ca24ae918058e5427b99 258 PANTHER PTHR10859 13 243 1.2E-63 T 22-04-2016 TOLA_RS01435 d7263702d731ca24ae918058e5427b99 258 SUPERFAMILY SSF53448 11 233 1.62E-38 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS01435 d7263702d731ca24ae918058e5427b99 258 Pfam PF00535 Glycosyl transferase family 2 17 180 1.5E-24 T 22-04-2016 IPR001173 Glycosyltransferase 2-like TOLA_RS15125 d756a9d65f636a98be1e31648550aace 305 Pfam PF16074 Type IV Pilus-assembly protein W 175 297 1.8E-16 T 22-04-2016 IPR032092 Type IV Pilus-assembly protein W GO:0043683 TOLA_RS10785 6207c47cb242f88c13920eef0d5617f4 334 PANTHER PTHR11732 14 330 2.2E-167 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta TOLA_RS10785 6207c47cb242f88c13920eef0d5617f4 334 SUPERFAMILY SSF51430 14 329 6.15E-88 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS10785 6207c47cb242f88c13920eef0d5617f4 334 PANTHER PTHR11732:SF191 14 330 2.2E-167 T 22-04-2016 TOLA_RS10785 6207c47cb242f88c13920eef0d5617f4 334 Gene3D G3DSA:3.20.20.100 13 329 3.3E-85 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS10785 6207c47cb242f88c13920eef0d5617f4 334 Pfam PF00248 Aldo/keto reductase family 29 329 1.1E-68 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS12960 10294124d4eaecf0b63c8ad6d85e0b91 306 PANTHER PTHR10264 8 302 5.1E-117 T 22-04-2016 IPR001972 Stomatin family GO:0016020 TOLA_RS12960 10294124d4eaecf0b63c8ad6d85e0b91 306 PANTHER PTHR10264:SF27 8 302 5.1E-117 T 22-04-2016 TOLA_RS12960 10294124d4eaecf0b63c8ad6d85e0b91 306 PRINTS PR00721 Stomatin signature 111 128 1.5E-28 T 22-04-2016 IPR001972 Stomatin family GO:0016020 TOLA_RS12960 10294124d4eaecf0b63c8ad6d85e0b91 306 PRINTS PR00721 Stomatin signature 76 97 1.5E-28 T 22-04-2016 IPR001972 Stomatin family GO:0016020 TOLA_RS12960 10294124d4eaecf0b63c8ad6d85e0b91 306 PRINTS PR00721 Stomatin signature 155 173 1.5E-28 T 22-04-2016 IPR001972 Stomatin family GO:0016020 TOLA_RS12960 10294124d4eaecf0b63c8ad6d85e0b91 306 PRINTS PR00721 Stomatin signature 174 195 1.5E-28 T 22-04-2016 IPR001972 Stomatin family GO:0016020 TOLA_RS12960 10294124d4eaecf0b63c8ad6d85e0b91 306 PRINTS PR00721 Stomatin signature 131 154 1.5E-28 T 22-04-2016 IPR001972 Stomatin family GO:0016020 TOLA_RS12960 10294124d4eaecf0b63c8ad6d85e0b91 306 SMART SM00244 21 179 4.7E-56 T 22-04-2016 IPR001107 Band 7 domain TOLA_RS12960 10294124d4eaecf0b63c8ad6d85e0b91 306 Pfam PF01145 SPFH domain / Band 7 family 25 194 3.3E-32 T 22-04-2016 IPR001107 Band 7 domain TOLA_RS12960 10294124d4eaecf0b63c8ad6d85e0b91 306 SUPERFAMILY SSF117892 52 186 1.7E-39 T 22-04-2016 IPR001107 Band 7 domain TOLA_RS12960 10294124d4eaecf0b63c8ad6d85e0b91 306 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 22-04-2016 IPR018080 Band 7/stomatin-like, conserved site TOLA_RS01120 cdd554ea0057615219a3cc068c303211 703 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 32 550 1.9E-162 T 22-04-2016 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset TOLA_RS01120 cdd554ea0057615219a3cc068c303211 703 SUPERFAMILY SSF69279 211 394 3.4E-26 T 22-04-2016 TOLA_RS01120 cdd554ea0057615219a3cc068c303211 703 Gene3D G3DSA:2.40.50.230 401 482 5.1E-38 T 22-04-2016 IPR006531 Gp5 N-terminal TOLA_RS01120 cdd554ea0057615219a3cc068c303211 703 SUPERFAMILY SSF69255 394 482 3.14E-33 T 22-04-2016 TOLA_RS01120 cdd554ea0057615219a3cc068c303211 703 Gene3D G3DSA:3.55.50.10 116 208 1.6E-32 T 22-04-2016 TOLA_RS01120 cdd554ea0057615219a3cc068c303211 703 PANTHER PTHR32305:SF11 21 663 6.8E-147 T 22-04-2016 TOLA_RS01120 cdd554ea0057615219a3cc068c303211 703 PANTHER PTHR32305 21 663 6.8E-147 T 22-04-2016 TOLA_RS01120 cdd554ea0057615219a3cc068c303211 703 Pfam PF05954 Phage late control gene D protein (GPD) 48 359 2.5E-68 T 22-04-2016 TOLA_RS01120 cdd554ea0057615219a3cc068c303211 703 SUPERFAMILY SSF69349 472 654 7.77E-35 T 22-04-2016 TOLA_RS01120 cdd554ea0057615219a3cc068c303211 703 SUPERFAMILY SSF69279 29 205 4.36E-52 T 22-04-2016 TOLA_RS01120 cdd554ea0057615219a3cc068c303211 703 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 40 534 4.6E-114 T 22-04-2016 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein TOLA_RS12990 5f1dc7a7a1432d3506143dd2553bf91c 500 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 38 495 1.6E-147 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 TOLA_RS12990 5f1dc7a7a1432d3506143dd2553bf91c 500 PIRSF PIRSF002457 8 500 4.5E-138 T 22-04-2016 IPR030676 Citrate carrier CitT-related TOLA_RS12990 5f1dc7a7a1432d3506143dd2553bf91c 500 Pfam PF00939 Sodium:sulfate symporter transmembrane region 24 499 2.1E-148 T 22-04-2016 IPR001898 Sodium/sulphate symporter GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 TOLA_RS12990 5f1dc7a7a1432d3506143dd2553bf91c 500 PANTHER PTHR10283:SF13 108 499 2.5E-165 T 22-04-2016 IPR030676 Citrate carrier CitT-related TOLA_RS12990 5f1dc7a7a1432d3506143dd2553bf91c 500 PANTHER PTHR10283:SF13 14 92 2.5E-165 T 22-04-2016 IPR030676 Citrate carrier CitT-related TOLA_RS12990 5f1dc7a7a1432d3506143dd2553bf91c 500 PANTHER PTHR10283 108 499 2.5E-165 T 22-04-2016 TOLA_RS12990 5f1dc7a7a1432d3506143dd2553bf91c 500 PANTHER PTHR10283 14 92 2.5E-165 T 22-04-2016 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 92 345 1.1E-52 T 22-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01180 Arginine decarboxylase signature 173 194 1.2E-71 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01180 Arginine decarboxylase signature 465 486 1.2E-71 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01180 Arginine decarboxylase signature 197 219 1.2E-71 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01180 Arginine decarboxylase signature 543 564 1.2E-71 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01180 Arginine decarboxylase signature 147 162 1.2E-71 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01180 Arginine decarboxylase signature 324 341 1.2E-71 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01180 Arginine decarboxylase signature 90 104 1.2E-71 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01180 Arginine decarboxylase signature 490 515 1.2E-71 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01180 Arginine decarboxylase signature 66 81 1.2E-71 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 SUPERFAMILY SSF51419 66 346 4.74E-66 T 22-04-2016 IPR029066 PLP-binding barrel TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 98 116 1.7E-12 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 334 353 1.7E-12 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 543 556 1.7E-12 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 240 253 1.7E-12 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 278 291 - T 22-04-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Reactome: REACT_13 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 Gene3D G3DSA:3.20.20.10 68 333 1.5E-59 T 22-04-2016 IPR029066 PLP-binding barrel TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 453 561 1.3E-22 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 SUPERFAMILY SSF50621 461 571 3.31E-7 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PIRSF PIRSF001336 1 635 2.0E-241 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 Gene3D G3DSA:2.40.37.10 456 587 1.9E-11 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 Gene3D G3DSA:2.40.37.10 334 357 1.9E-11 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 2 634 40.797 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 TIGRFAM TIGR01273 speA: arginine decarboxylase 4 633 4.6E-250 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PANTHER PTHR11482 440 598 1.1E-238 T 22-04-2016 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PANTHER PTHR11482 1 365 1.1E-238 T 22-04-2016 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PANTHER PTHR11482:SF36 440 598 1.1E-238 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS01990 bceeb30a27372e80a476bf7fcc103c25 635 PANTHER PTHR11482:SF36 1 365 1.1E-238 T 22-04-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 186 789 2.7E-169 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 249 770 1.8E-88 T 22-04-2016 IPR001757 P-type ATPase GO:0016021 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 SUPERFAMILY SSF56784 537 786 7.15E-56 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 SUPERFAMILY SSF56784 478 498 7.15E-56 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PANTHER PTHR24093 114 789 1.6E-223 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PANTHER PTHR24093 37 81 1.6E-223 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PRINTS PR00943 Copper-transporting ATPase signature 656 673 1.0E-16 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PRINTS PR00943 Copper-transporting ATPase signature 401 415 1.0E-16 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PRINTS PR00943 Copper-transporting ATPase signature 190 209 1.0E-16 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PRINTS PR00943 Copper-transporting ATPase signature 752 766 1.0E-16 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PRINTS PR00943 Copper-transporting ATPase signature 267 285 1.0E-16 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PRINTS PR00943 Copper-transporting ATPase signature 463 478 1.0E-16 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 626 636 7.2E-28 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 480 494 7.2E-28 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 702 714 7.2E-28 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 604 615 7.2E-28 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 328 342 7.2E-28 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 679 698 7.2E-28 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 Gene3D G3DSA:1.10.620.20 37 80 1.3E-4 T 22-04-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 SUPERFAMILY SSF81653 281 378 2.22E-26 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 482 488 - T 22-04-2016 IPR018303 P-type ATPase, phosphorylation site TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PANTHER PTHR24093:SF332 114 789 1.6E-223 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 PANTHER PTHR24093:SF332 37 81 1.6E-223 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 SMART SM00746 37 74 2.8E-12 T 22-04-2016 IPR011017 TRASH domain TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 Pfam PF00122 E1-E2 ATPase 249 471 1.3E-66 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 Pfam PF04945 YHS domain 36 80 1.8E-18 T 22-04-2016 IPR007029 YHS domain TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 SUPERFAMILY SSF81665 728 775 9.29E-13 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 SUPERFAMILY SSF81665 379 474 9.29E-13 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 SUPERFAMILY SSF81665 265 281 9.29E-13 T 22-04-2016 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 Gene3D G3DSA:2.70.150.10 207 378 2.5E-30 T 22-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 Gene3D G3DSA:3.40.50.1000 607 748 7.3E-52 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 Gene3D G3DSA:3.40.50.1000 451 494 7.3E-52 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 SUPERFAMILY SSF47240 33 81 2.05E-8 T 22-04-2016 IPR009078 Ferritin-like superfamily TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 205 788 5.7E-180 T 22-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 Gene3D G3DSA:3.40.1110.10 495 606 2.4E-21 T 22-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 TOLA_RS10095 43210954fe5da382b4f27ff3701aeb62 793 Pfam PF00702 haloacid dehalogenase-like hydrolase 476 693 2.3E-39 T 22-04-2016 TOLA_RS07145 7034ba522e20f610e8ada8a7161d1c1b 203 Pfam PF09186 Domain of unknown function (DUF1949) 142 195 2.1E-7 T 22-04-2016 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal TOLA_RS07145 7034ba522e20f610e8ada8a7161d1c1b 203 Pfam PF01205 Uncharacterized protein family UPF0029 19 125 3.2E-28 T 22-04-2016 IPR001498 Impact, N-terminal TOLA_RS07145 7034ba522e20f610e8ada8a7161d1c1b 203 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 195 3.5E-55 T 22-04-2016 IPR015796 Impact family, bacterial/archaeal TOLA_RS07145 7034ba522e20f610e8ada8a7161d1c1b 203 Gene3D G3DSA:3.30.230.30 5 128 8.2E-43 T 22-04-2016 IPR001498 Impact, N-terminal TOLA_RS07145 7034ba522e20f610e8ada8a7161d1c1b 203 SUPERFAMILY SSF54980 136 200 3.17E-10 T 22-04-2016 IPR009022 Elongation factor G, III-V domain TOLA_RS07145 7034ba522e20f610e8ada8a7161d1c1b 203 Gene3D G3DSA:3.30.70.240 136 202 5.8E-11 T 22-04-2016 IPR000640 Translation elongation factor EFG, V domain TOLA_RS07145 7034ba522e20f610e8ada8a7161d1c1b 203 PANTHER PTHR16301 1 191 2.1E-53 T 22-04-2016 IPR023582 Impact family TOLA_RS07145 7034ba522e20f610e8ada8a7161d1c1b 203 SUPERFAMILY SSF54211 2 129 1.21E-40 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS07145 7034ba522e20f610e8ada8a7161d1c1b 203 PANTHER PTHR16301:SF0 1 191 2.1E-53 T 22-04-2016 TOLA_RS08520 3a94298ec937da95004b5a1e707f23f7 257 Gene3D G3DSA:3.40.1010.10 9 117 2.0E-28 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 TOLA_RS08520 3a94298ec937da95004b5a1e707f23f7 257 SUPERFAMILY SSF53790 7 255 1.27E-63 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS08520 3a94298ec937da95004b5a1e707f23f7 257 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 10 255 2.4E-99 T 22-04-2016 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 TOLA_RS08520 3a94298ec937da95004b5a1e707f23f7 257 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 13 27 - T 22-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS08520 3a94298ec937da95004b5a1e707f23f7 257 PANTHER PTHR21091 10 215 3.1E-70 T 22-04-2016 TOLA_RS08520 3a94298ec937da95004b5a1e707f23f7 257 Gene3D G3DSA:3.30.950.10 118 236 1.3E-37 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 TOLA_RS08520 3a94298ec937da95004b5a1e707f23f7 257 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 215 2.4E-39 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS08520 3a94298ec937da95004b5a1e707f23f7 257 PANTHER PTHR21091:SF17 10 215 3.1E-70 T 22-04-2016 TOLA_RS05085 956905bba11785e53acd471b537931fb 300 SUPERFAMILY SSF46785 6 85 7.95E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05085 956905bba11785e53acd471b537931fb 300 SUPERFAMILY SSF53850 90 298 2.71E-38 T 22-04-2016 TOLA_RS05085 956905bba11785e53acd471b537931fb 300 Gene3D G3DSA:1.10.10.10 6 86 6.6E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05085 956905bba11785e53acd471b537931fb 300 Pfam PF03466 LysR substrate binding domain 90 297 9.6E-35 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS05085 956905bba11785e53acd471b537931fb 300 PANTHER PTHR30537:SF8 1 298 9.3E-90 T 22-04-2016 TOLA_RS05085 956905bba11785e53acd471b537931fb 300 PANTHER PTHR30537 1 298 9.3E-90 T 22-04-2016 TOLA_RS05085 956905bba11785e53acd471b537931fb 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.7E-17 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS05085 956905bba11785e53acd471b537931fb 300 Gene3D G3DSA:3.40.190.10 93 193 1.4E-29 T 22-04-2016 TOLA_RS02395 dade00997f6b53dd1051237d001169d0 302 PANTHER PTHR30213:SF0 1 291 3.7E-67 T 22-04-2016 TOLA_RS02395 dade00997f6b53dd1051237d001169d0 302 PANTHER PTHR30213 1 291 3.7E-67 T 22-04-2016 TOLA_RS02395 dade00997f6b53dd1051237d001169d0 302 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 24 292 21.126 T 22-04-2016 IPR023679 Uncharacterised protein family UPF0761, bacterial TOLA_RS02395 dade00997f6b53dd1051237d001169d0 302 Pfam PF03631 Virulence factor BrkB 40 286 2.2E-54 T 22-04-2016 IPR017039 Virulence factor BrkB TOLA_RS02395 dade00997f6b53dd1051237d001169d0 302 PIRSF PIRSF035875 11 299 1.5E-54 T 22-04-2016 IPR017039 Virulence factor BrkB TOLA_RS02395 dade00997f6b53dd1051237d001169d0 302 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 29 287 3.2E-69 T 22-04-2016 IPR017039 Virulence factor BrkB TOLA_RS04030 90082028dd7e351b24cd6112188a49fe 246 Hamap MF_01589 tRNA (cmo5U34)-methyltransferase [cmoA]. 1 240 43.228 T 22-04-2016 IPR005271 tRNA (cmo5U34)-methyltransferase GO:0002098|GO:0016300 TOLA_RS04030 90082028dd7e351b24cd6112188a49fe 246 PANTHER PTHR10108 1 239 7.7E-103 T 22-04-2016 TOLA_RS04030 90082028dd7e351b24cd6112188a49fe 246 Pfam PF13649 Methyltransferase domain 60 156 6.8E-14 T 22-04-2016 TOLA_RS04030 90082028dd7e351b24cd6112188a49fe 246 PIRSF PIRSF006325 1 241 7.2E-119 T 22-04-2016 IPR005271 tRNA (cmo5U34)-methyltransferase GO:0002098|GO:0016300 TOLA_RS04030 90082028dd7e351b24cd6112188a49fe 246 Gene3D G3DSA:3.40.50.150 17 240 1.9E-64 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04030 90082028dd7e351b24cd6112188a49fe 246 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 2 240 9.9E-115 T 22-04-2016 IPR005271 tRNA (cmo5U34)-methyltransferase GO:0002098|GO:0016300 TOLA_RS04030 90082028dd7e351b24cd6112188a49fe 246 SUPERFAMILY SSF53335 18 240 7.12E-40 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04030 90082028dd7e351b24cd6112188a49fe 246 PANTHER PTHR10108:SF809 1 239 7.7E-103 T 22-04-2016 TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 55 2.3E-6 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 25 39 2.3E-6 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 PANTHER PTHR11751 2 68 1.2E-23 T 22-04-2016 TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 65 1.1E-18 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 Gene3D G3DSA:1.10.10.10 2 62 1.7E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 PANTHER PTHR11751:SF292 2 68 1.2E-23 T 22-04-2016 TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 Gene3D G3DSA:3.40.1410.10 63 177 3.6E-32 T 22-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 SUPERFAMILY SSF64288 54 178 3.14E-28 T 22-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 Pfam PF07702 UTRA domain 88 176 3.3E-17 T 22-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 SUPERFAMILY SSF46785 2 71 5.68E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 PANTHER PTHR11751 115 138 1.2E-23 T 22-04-2016 TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 PANTHER PTHR11751:SF292 115 138 1.2E-23 T 22-04-2016 TOLA_RS13500 ea9429ed980a24cc27ab19346f5a469a 182 SMART SM00345 6 65 3.1E-16 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS01870 2666cd381ef6e2f9c9c9fc7d5ebe9f0c 396 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 66 297 2.4E-14 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TOLA_RS01870 2666cd381ef6e2f9c9c9fc7d5ebe9f0c 396 SUPERFAMILY SSF111369 54 302 7.59E-88 T 22-04-2016 TOLA_RS01870 2666cd381ef6e2f9c9c9fc7d5ebe9f0c 396 PANTHER PTHR30158:SF3 1 393 3.1E-167 T 22-04-2016 TOLA_RS01870 2666cd381ef6e2f9c9c9fc7d5ebe9f0c 396 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 43 379 7.2E-83 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 TOLA_RS01870 2666cd381ef6e2f9c9c9fc7d5ebe9f0c 396 Gene3D G3DSA:2.40.50.100 68 101 1.1E-27 T 22-04-2016 TOLA_RS01870 2666cd381ef6e2f9c9c9fc7d5ebe9f0c 396 Gene3D G3DSA:2.40.50.100 176 211 1.1E-27 T 22-04-2016 TOLA_RS01870 2666cd381ef6e2f9c9c9fc7d5ebe9f0c 396 PANTHER PTHR30158 1 393 3.1E-167 T 22-04-2016 TOLA_RS01870 2666cd381ef6e2f9c9c9fc7d5ebe9f0c 396 Pfam PF00529 HlyD membrane-fusion protein of T1SS 201 364 7.8E-9 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 TOLA_RS14100 1865778465075ba9f04c9480ec5e5c27 69 Pfam PF06005 Protein of unknown function (DUF904) 1 64 5.6E-24 T 22-04-2016 IPR009252 Cell division protein ZapB GO:0000917|GO:0005737|GO:0043093 TOLA_RS14100 1865778465075ba9f04c9480ec5e5c27 69 Gene3D G3DSA:1.20.5.370 27 56 5.2E-4 T 22-04-2016 IPR014751 DNA repair protein XRCC4, C-terminal GO:0003677|GO:0006302|GO:0006310 TOLA_RS14100 1865778465075ba9f04c9480ec5e5c27 69 Hamap MF_01196 Cell division protein ZapB [zapB]. 1 65 16.425 T 22-04-2016 IPR009252 Cell division protein ZapB GO:0000917|GO:0005737|GO:0043093 TOLA_RS13165 419e4503d60b1fcd6ed52360fa8df500 457 Pfam PF01235 Sodium:alanine symporter family 54 446 2.5E-139 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS13165 419e4503d60b1fcd6ed52360fa8df500 457 PANTHER PTHR30330:SF3 1 443 4.2E-219 T 22-04-2016 TOLA_RS13165 419e4503d60b1fcd6ed52360fa8df500 457 PANTHER PTHR30330 1 443 4.2E-219 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS13165 419e4503d60b1fcd6ed52360fa8df500 457 TIGRFAM TIGR00835 agcS: amino acid carrier protein 14 437 3.6E-154 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS13165 419e4503d60b1fcd6ed52360fa8df500 457 PRINTS PR00175 Sodium/alanine symporter signature 350 372 1.9E-53 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS13165 419e4503d60b1fcd6ed52360fa8df500 457 PRINTS PR00175 Sodium/alanine symporter signature 409 429 1.9E-53 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS13165 419e4503d60b1fcd6ed52360fa8df500 457 PRINTS PR00175 Sodium/alanine symporter signature 182 200 1.9E-53 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS13165 419e4503d60b1fcd6ed52360fa8df500 457 PRINTS PR00175 Sodium/alanine symporter signature 90 112 1.9E-53 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS13165 419e4503d60b1fcd6ed52360fa8df500 457 PRINTS PR00175 Sodium/alanine symporter signature 210 229 1.9E-53 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS13165 419e4503d60b1fcd6ed52360fa8df500 457 PRINTS PR00175 Sodium/alanine symporter signature 305 323 1.9E-53 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS13165 419e4503d60b1fcd6ed52360fa8df500 457 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 90 105 - T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS13490 cec4052d1220f78fe222b8d15613630b 506 PANTHER PTHR22773:SF40 3 486 2.6E-185 T 22-04-2016 TOLA_RS13490 cec4052d1220f78fe222b8d15613630b 506 Pfam PF00361 Proton-conducting membrane transporter 134 431 6.4E-69 T 22-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 TOLA_RS13490 cec4052d1220f78fe222b8d15613630b 506 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 4 487 6.0E-175 T 22-04-2016 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 TOLA_RS13490 cec4052d1220f78fe222b8d15613630b 506 PANTHER PTHR22773 3 486 2.6E-185 T 22-04-2016 TOLA_RS13490 cec4052d1220f78fe222b8d15613630b 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 140 159 9.1E-38 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 TOLA_RS13490 cec4052d1220f78fe222b8d15613630b 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 175 199 9.1E-38 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 TOLA_RS13490 cec4052d1220f78fe222b8d15613630b 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 390 416 9.1E-38 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 TOLA_RS13490 cec4052d1220f78fe222b8d15613630b 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 338 357 9.1E-38 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 TOLA_RS13490 cec4052d1220f78fe222b8d15613630b 506 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 250 274 9.1E-38 T 22-04-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 TOLA_RS12145 47cd80b6ea7c7b86209ce244a126f4bc 155 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 140 8.6E-48 T 22-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 TOLA_RS12145 47cd80b6ea7c7b86209ce244a126f4bc 155 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 10 131 1.2E-40 T 22-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 TOLA_RS12145 47cd80b6ea7c7b86209ce244a126f4bc 155 SUPERFAMILY SSF52540 28 127 2.74E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12145 47cd80b6ea7c7b86209ce244a126f4bc 155 Gene3D G3DSA:3.40.50.300 7 151 6.1E-49 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12145 47cd80b6ea7c7b86209ce244a126f4bc 155 PANTHER PTHR33540 5 152 1.7E-46 T 22-04-2016 TOLA_RS00430 8117d43d866270c58a829b3586fd564c 198 PANTHER PTHR10204 1 195 1.1E-65 T 22-04-2016 TOLA_RS00430 8117d43d866270c58a829b3586fd564c 198 Gene3D G3DSA:3.40.50.360 1 181 7.2E-46 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS00430 8117d43d866270c58a829b3586fd564c 198 SUPERFAMILY SSF52218 1 187 4.03E-49 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS00430 8117d43d866270c58a829b3586fd564c 198 PANTHER PTHR10204:SF42 1 195 1.1E-65 T 22-04-2016 TOLA_RS00430 8117d43d866270c58a829b3586fd564c 198 Pfam PF02525 Flavodoxin-like fold 2 171 2.1E-43 T 22-04-2016 IPR003680 Flavodoxin-like fold TOLA_RS01055 430eddcd53e67b68e5a828aa4be3ef6a 491 PANTHER PTHR35565 16 491 0.0 T 22-04-2016 TOLA_RS01055 430eddcd53e67b68e5a828aa4be3ef6a 491 PANTHER PTHR35565:SF1 16 491 0.0 T 22-04-2016 TOLA_RS01055 430eddcd53e67b68e5a828aa4be3ef6a 491 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 17 489 1.0E-216 T 22-04-2016 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath TOLA_RS01055 430eddcd53e67b68e5a828aa4be3ef6a 491 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 65 489 7.2E-183 T 22-04-2016 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath TOLA_RS04565 37e278fe9282619393512d66c4c444b9 216 PIRSF PIRSF006170 1 209 1.7E-56 T 22-04-2016 IPR026039 Uncharacterised protein family UPF0070 TOLA_RS04565 37e278fe9282619393512d66c4c444b9 216 PANTHER PTHR38035 2 205 9.8E-61 T 22-04-2016 TOLA_RS04565 37e278fe9282619393512d66c4c444b9 216 Pfam PF09976 Tetratricopeptide repeat-like domain 15 204 6.1E-61 T 22-04-2016 IPR018704 Tetratricopeptide repeat-like domain TOLA_RS04565 37e278fe9282619393512d66c4c444b9 216 SUPERFAMILY SSF48452 90 190 3.8E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS04565 37e278fe9282619393512d66c4c444b9 216 Gene3D G3DSA:1.25.40.10 92 193 2.0E-5 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS02210 1b0040df36d76aa4c5fc3d7a9672c045 142 PANTHER PTHR37486:SF1 1 142 1.6E-68 T 22-04-2016 TOLA_RS02210 1b0040df36d76aa4c5fc3d7a9672c045 142 PANTHER PTHR37486 1 142 1.6E-68 T 22-04-2016 TOLA_RS02210 1b0040df36d76aa4c5fc3d7a9672c045 142 Gene3D G3DSA:2.30.30.220 1 106 1.8E-48 T 22-04-2016 IPR007481 Stringent starvation protein B TOLA_RS02210 1b0040df36d76aa4c5fc3d7a9672c045 142 SUPERFAMILY SSF101738 1 112 6.8E-47 T 22-04-2016 IPR007481 Stringent starvation protein B TOLA_RS02210 1b0040df36d76aa4c5fc3d7a9672c045 142 PIRSF PIRSF005276 1 142 1.5E-55 T 22-04-2016 IPR007481 Stringent starvation protein B TOLA_RS02210 1b0040df36d76aa4c5fc3d7a9672c045 142 Pfam PF04386 Stringent starvation protein B 4 142 2.7E-38 T 22-04-2016 IPR007481 Stringent starvation protein B TOLA_RS09015 b3068b22da5ddd7fec800f8352f2eb21 253 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 212 1.1E-47 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS09015 b3068b22da5ddd7fec800f8352f2eb21 253 Gene3D G3DSA:3.40.1010.10 2 118 2.5E-42 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 TOLA_RS09015 b3068b22da5ddd7fec800f8352f2eb21 253 PANTHER PTHR21091:SF16 1 212 1.8E-71 T 22-04-2016 TOLA_RS09015 b3068b22da5ddd7fec800f8352f2eb21 253 Gene3D G3DSA:3.30.950.10 119 244 3.9E-37 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 TOLA_RS09015 b3068b22da5ddd7fec800f8352f2eb21 253 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 22-04-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS09015 b3068b22da5ddd7fec800f8352f2eb21 253 SUPERFAMILY SSF53790 1 242 1.22E-69 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS09015 b3068b22da5ddd7fec800f8352f2eb21 253 PANTHER PTHR21091 1 212 1.8E-71 T 22-04-2016 TOLA_RS09015 b3068b22da5ddd7fec800f8352f2eb21 253 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 238 1.8E-86 T 22-04-2016 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 TOLA_RS14530 f7518e0ed39e087d5c262a34059ffd23 225 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 71 86 - T 22-04-2016 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 TOLA_RS14530 f7518e0ed39e087d5c262a34059ffd23 225 SUPERFAMILY SSF55681 4 206 1.08E-69 T 22-04-2016 TOLA_RS14530 f7518e0ed39e087d5c262a34059ffd23 225 Gene3D G3DSA:3.90.1550.10 4 203 1.4E-71 T 22-04-2016 TOLA_RS14530 f7518e0ed39e087d5c262a34059ffd23 225 Hamap MF_00013 Octanoyltransferase [lipB]. 5 206 37.559 T 22-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 TOLA_RS14530 f7518e0ed39e087d5c262a34059ffd23 225 Pfam PF03099 Biotin/lipoate A/B protein ligase family 57 159 1.5E-7 T 22-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 TOLA_RS14530 f7518e0ed39e087d5c262a34059ffd23 225 PANTHER PTHR10993 6 217 7.2E-78 T 22-04-2016 TOLA_RS14530 f7518e0ed39e087d5c262a34059ffd23 225 PIRSF PIRSF016262 2 214 3.5E-60 T 22-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 TOLA_RS14530 f7518e0ed39e087d5c262a34059ffd23 225 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 27 203 4.0E-64 T 22-04-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 TOLA_RS14530 f7518e0ed39e087d5c262a34059ffd23 225 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 75 128 2.0E-16 T 22-04-2016 TOLA_RS12970 2f2effb87ebf379a259ec1b00c7df764 329 PANTHER PTHR11540 1 317 5.4E-157 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TOLA_RS12970 2f2effb87ebf379a259ec1b00c7df764 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 146 158 - T 22-04-2016 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: REACT_474 TOLA_RS12970 2f2effb87ebf379a259ec1b00c7df764 329 TIGRFAM TIGR01772 MDH_euk_gproteo: malate dehydrogenase, NAD-dependent 2 311 1.1E-118 T 22-04-2016 IPR010097 Malate dehydrogenase, type 1 GO:0006108|GO:0030060|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 TOLA_RS12970 2f2effb87ebf379a259ec1b00c7df764 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 147 310 7.3E-42 T 22-04-2016 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 TOLA_RS12970 2f2effb87ebf379a259ec1b00c7df764 329 SUPERFAMILY SSF56327 146 309 7.57E-41 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TOLA_RS12970 2f2effb87ebf379a259ec1b00c7df764 329 PIRSF PIRSF000102 1 312 1.1E-55 T 22-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TOLA_RS12970 2f2effb87ebf379a259ec1b00c7df764 329 SUPERFAMILY SSF51735 1 145 6.15E-35 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS12970 2f2effb87ebf379a259ec1b00c7df764 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 1 145 1.0E-40 T 22-04-2016 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 TOLA_RS12970 2f2effb87ebf379a259ec1b00c7df764 329 Gene3D G3DSA:3.40.50.720 1 146 4.3E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS12970 2f2effb87ebf379a259ec1b00c7df764 329 PANTHER PTHR11540:SF22 1 317 5.4E-157 T 22-04-2016 TOLA_RS12970 2f2effb87ebf379a259ec1b00c7df764 329 Gene3D G3DSA:3.90.110.10 147 310 3.5E-56 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TOLA_RS10380 460bb97b35a1089ef2f58252d63b7c48 295 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 3 290 8.7E-103 T 22-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family TOLA_RS10380 460bb97b35a1089ef2f58252d63b7c48 295 Gene3D G3DSA:3.40.50.720 2 195 1.7E-38 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10380 460bb97b35a1089ef2f58252d63b7c48 295 PANTHER PTHR10491:SF4 2 290 1.2E-96 T 22-04-2016 TOLA_RS10380 460bb97b35a1089ef2f58252d63b7c48 295 Pfam PF04321 RmlD substrate binding domain 3 291 9.6E-109 T 22-04-2016 IPR029903 RmlD-like substrate binding domain TOLA_RS10380 460bb97b35a1089ef2f58252d63b7c48 295 SUPERFAMILY SSF51735 3 292 6.35E-100 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS10380 460bb97b35a1089ef2f58252d63b7c48 295 PANTHER PTHR10491 2 290 1.2E-96 T 22-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family TOLA_RS10380 460bb97b35a1089ef2f58252d63b7c48 295 Gene3D G3DSA:3.90.25.10 221 283 4.6E-31 T 22-04-2016 TOLA_RS11805 35598999e89f515638b458b859d2cb0e 72 PIRSF PIRSF002599 1 72 6.5E-23 T 22-04-2016 IPR012156 Cold shock, CspA GO:0003676 TOLA_RS11805 35598999e89f515638b458b859d2cb0e 72 PANTHER PTHR11544 1 66 3.2E-40 T 22-04-2016 TOLA_RS11805 35598999e89f515638b458b859d2cb0e 72 SMART SM00357 3 67 7.7E-26 T 22-04-2016 IPR011129 Cold shock protein GO:0003676 TOLA_RS11805 35598999e89f515638b458b859d2cb0e 72 Gene3D G3DSA:2.40.50.140 1 65 1.2E-29 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS11805 35598999e89f515638b458b859d2cb0e 72 SUPERFAMILY SSF50249 1 66 1.69E-23 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS11805 35598999e89f515638b458b859d2cb0e 72 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 22-04-2016 IPR019844 Cold-shock conserved site TOLA_RS11805 35598999e89f515638b458b859d2cb0e 72 TIGRFAM TIGR02381 cspD: cold shock domain protein CspD 1 67 4.0E-38 T 22-04-2016 IPR012751 CspD, cold shock GO:0003676|GO:0005737|GO:0006355|GO:0006950 TOLA_RS11805 35598999e89f515638b458b859d2cb0e 72 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 4.6E-28 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOLA_RS11805 35598999e89f515638b458b859d2cb0e 72 PANTHER PTHR11544:SF52 1 66 3.2E-40 T 22-04-2016 TOLA_RS11805 35598999e89f515638b458b859d2cb0e 72 PRINTS PR00050 Cold shock protein signature 40 58 1.9E-15 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOLA_RS11805 35598999e89f515638b458b859d2cb0e 72 PRINTS PR00050 Cold shock protein signature 25 34 1.9E-15 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOLA_RS11805 35598999e89f515638b458b859d2cb0e 72 PRINTS PR00050 Cold shock protein signature 4 19 1.9E-15 T 22-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 35 282 6.0E-72 T 22-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 286 390 1.7E-17 T 22-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 191 204 2.9E-26 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 78 90 2.9E-26 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 370 383 2.9E-26 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 271 290 2.9E-26 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 58 76 2.9E-26 T 22-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 PRINTS PR01181 Diaminopimelate decarboxylase signature 76 93 1.3E-29 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 PRINTS PR01181 Diaminopimelate decarboxylase signature 380 402 1.3E-29 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 PRINTS PR01181 Diaminopimelate decarboxylase signature 299 317 1.3E-29 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 PRINTS PR01181 Diaminopimelate decarboxylase signature 165 174 1.3E-29 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 Gene3D G3DSA:2.40.37.10 269 414 3.2E-47 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 Gene3D G3DSA:3.20.20.10 37 268 1.2E-83 T 22-04-2016 IPR029066 PLP-binding barrel TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 PANTHER PTHR11482:SF5 4 416 2.8E-178 T 22-04-2016 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 58 76 - T 22-04-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 SUPERFAMILY SSF50621 255 414 8.79E-53 T 22-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 16 413 40.863 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 6 411 2.1E-163 T 22-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 PANTHER PTHR11482 4 416 2.8E-178 T 22-04-2016 TOLA_RS16020 24added85f2a53c9166f7b1d9badbc0f 416 SUPERFAMILY SSF51419 27 283 1.6E-82 T 22-04-2016 IPR029066 PLP-binding barrel TOLA_RS10105 e356cf5e3800f8f854afec4e63df1a80 317 SUPERFAMILY SSF46785 9 115 4.54E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10105 e356cf5e3800f8f854afec4e63df1a80 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 65 6.0E-17 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10105 e356cf5e3800f8f854afec4e63df1a80 317 Pfam PF03466 LysR substrate binding domain 93 299 7.1E-36 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS10105 e356cf5e3800f8f854afec4e63df1a80 317 PANTHER PTHR30537:SF5 1 316 7.7E-93 T 22-04-2016 TOLA_RS10105 e356cf5e3800f8f854afec4e63df1a80 317 SUPERFAMILY SSF53850 91 302 4.89E-38 T 22-04-2016 TOLA_RS10105 e356cf5e3800f8f854afec4e63df1a80 317 Gene3D G3DSA:3.40.190.10 96 180 3.8E-22 T 22-04-2016 TOLA_RS10105 e356cf5e3800f8f854afec4e63df1a80 317 Gene3D G3DSA:1.10.10.10 10 87 9.1E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10105 e356cf5e3800f8f854afec4e63df1a80 317 Gene3D G3DSA:3.40.190.10 181 264 1.2E-5 T 22-04-2016 TOLA_RS10105 e356cf5e3800f8f854afec4e63df1a80 317 PANTHER PTHR30537 1 316 7.7E-93 T 22-04-2016 TOLA_RS01465 522a005248379587ef4845d91881b6d9 433 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 12 415 1.7E-116 T 22-04-2016 IPR005219 Conserved hypothetical protein CHP00155 TOLA_RS01465 522a005248379587ef4845d91881b6d9 433 PANTHER PTHR30462 19 422 5.2E-154 T 22-04-2016 TOLA_RS01465 522a005248379587ef4845d91881b6d9 433 PANTHER PTHR30462:SF3 19 422 5.2E-154 T 22-04-2016 TOLA_RS01465 522a005248379587ef4845d91881b6d9 433 Pfam PF04403 Paraquat-inducible protein A 57 207 5.9E-38 T 22-04-2016 IPR007498 Paraquat-inducible protein A TOLA_RS01465 522a005248379587ef4845d91881b6d9 433 Pfam PF04403 Paraquat-inducible protein A 261 416 7.6E-59 T 22-04-2016 IPR007498 Paraquat-inducible protein A TOLA_RS04680 13f9eb47e2f60e7719384ac3dad7583b 154 Hamap MF_00042 Ribonuclease H [rnhA]. 2 150 36.403 T 22-04-2016 IPR022892 Ribonuclease H GO:0004523 TOLA_RS04680 13f9eb47e2f60e7719384ac3dad7583b 154 SUPERFAMILY SSF53098 4 141 1.52E-56 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS04680 13f9eb47e2f60e7719384ac3dad7583b 154 PANTHER PTHR10642 4 141 1.5E-58 T 22-04-2016 TOLA_RS04680 13f9eb47e2f60e7719384ac3dad7583b 154 Pfam PF00075 RNase H 3 141 1.1E-51 T 22-04-2016 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 TOLA_RS04680 13f9eb47e2f60e7719384ac3dad7583b 154 Gene3D G3DSA:3.30.420.10 3 142 2.9E-59 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS00165 8ded4a7ed2275db52e68d8ea2d2e5c03 344 PANTHER PTHR12526 16 344 5.2E-48 T 22-04-2016 TOLA_RS00165 8ded4a7ed2275db52e68d8ea2d2e5c03 344 SUPERFAMILY SSF53756 8 344 7.07E-64 T 22-04-2016 TOLA_RS00165 8ded4a7ed2275db52e68d8ea2d2e5c03 344 Pfam PF00534 Glycosyl transferases group 1 165 322 2.4E-32 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 TOLA_RS00165 8ded4a7ed2275db52e68d8ea2d2e5c03 344 Gene3D G3DSA:3.40.50.2000 167 321 7.5E-25 T 22-04-2016 TOLA_RS01100 465dd636e24cd310185a02de1bb7e746 288 PANTHER PTHR30329:SF7 119 278 1.3E-44 T 22-04-2016 TOLA_RS01100 465dd636e24cd310185a02de1bb7e746 288 Pfam PF09850 Type VI secretion system protein DotU 62 263 6.2E-60 T 22-04-2016 IPR017732 Type IV / VI secretion system, DotU TOLA_RS01100 465dd636e24cd310185a02de1bb7e746 288 PANTHER PTHR30329 119 278 1.3E-44 T 22-04-2016 TOLA_RS01100 465dd636e24cd310185a02de1bb7e746 288 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 61 269 5.8E-61 T 22-04-2016 IPR017732 Type IV / VI secretion system, DotU TOLA_RS11510 fbe134e43b28d91b44b1e74a8301b98c 128 SUPERFAMILY SSF81593 4 118 2.28E-31 T 22-04-2016 TOLA_RS11510 fbe134e43b28d91b44b1e74a8301b98c 128 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 6 122 1.4E-28 T 22-04-2016 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 TOLA_RS11510 fbe134e43b28d91b44b1e74a8301b98c 128 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 9 120 6.7E-29 T 22-04-2016 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 TOLA_RS11510 fbe134e43b28d91b44b1e74a8301b98c 128 Gene3D G3DSA:1.20.120.330 3 123 2.3E-35 T 22-04-2016 TOLA_RS02230 dd08f80d41143067895f123616661286 619 PANTHER PTHR38038:SF1 1 607 2.1E-97 T 22-04-2016 TOLA_RS02230 dd08f80d41143067895f123616661286 619 Pfam PF04348 LppC putative lipoprotein 43 600 1.4E-98 T 22-04-2016 IPR007443 Penicillin-binding protein activator LpoA TOLA_RS02230 dd08f80d41143067895f123616661286 619 SUPERFAMILY SSF53822 265 603 3.67E-65 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS02230 dd08f80d41143067895f123616661286 619 Gene3D G3DSA:3.40.50.2300 264 366 2.6E-50 T 22-04-2016 TOLA_RS02230 dd08f80d41143067895f123616661286 619 Gene3D G3DSA:3.40.50.2300 529 592 2.6E-50 T 22-04-2016 TOLA_RS02230 dd08f80d41143067895f123616661286 619 PANTHER PTHR38038 1 607 2.1E-97 T 22-04-2016 TOLA_RS02230 dd08f80d41143067895f123616661286 619 Gene3D G3DSA:3.40.50.2300 367 528 1.6E-35 T 22-04-2016 TOLA_RS12885 2b721812666b049853835ec5d80e27fa 437 SUPERFAMILY SSF55604 345 413 7.45E-6 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS12885 2b721812666b049853835ec5d80e27fa 437 Gene3D G3DSA:3.30.1360.60 345 416 1.2E-5 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS03130 43221f01c6668d21e1686b094ea6cbff 208 Pfam PF01810 LysE type translocator 16 205 2.6E-34 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS03130 43221f01c6668d21e1686b094ea6cbff 208 PIRSF PIRSF006324 1 208 5.8E-51 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS03130 43221f01c6668d21e1686b094ea6cbff 208 PANTHER PTHR30086:SF3 2 208 5.6E-63 T 22-04-2016 TOLA_RS03130 43221f01c6668d21e1686b094ea6cbff 208 PANTHER PTHR30086 2 208 5.6E-63 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS11530 59b087583e1825cb39712894d7e6d8c9 1009 Pfam PF04851 Type III restriction enzyme, res subunit 293 491 9.9E-15 T 22-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TOLA_RS11530 59b087583e1825cb39712894d7e6d8c9 1009 PANTHER PTHR30195 469 956 0.0 T 22-04-2016 TOLA_RS11530 59b087583e1825cb39712894d7e6d8c9 1009 PANTHER PTHR30195 1 444 0.0 T 22-04-2016 TOLA_RS11530 59b087583e1825cb39712894d7e6d8c9 1009 Gene3D G3DSA:3.40.50.300 279 494 6.1E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11530 59b087583e1825cb39712894d7e6d8c9 1009 SMART SM00487 289 513 7.9E-11 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS11530 59b087583e1825cb39712894d7e6d8c9 1009 PANTHER PTHR30195:SF13 469 956 0.0 T 22-04-2016 TOLA_RS11530 59b087583e1825cb39712894d7e6d8c9 1009 PANTHER PTHR30195:SF13 1 444 0.0 T 22-04-2016 TOLA_RS11530 59b087583e1825cb39712894d7e6d8c9 1009 SUPERFAMILY SSF52540 260 538 1.87E-24 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11530 59b087583e1825cb39712894d7e6d8c9 1009 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 134 229 4.2E-13 T 22-04-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 TOLA_RS08750 b270ecdbffa342501aa71a2e853d835b 316 PANTHER PTHR22550:SF12 1 314 4.8E-94 T 22-04-2016 TOLA_RS08750 b270ecdbffa342501aa71a2e853d835b 316 SMART SM00327 86 279 2.8E-22 T 22-04-2016 IPR002035 von Willebrand factor, type A TOLA_RS08750 b270ecdbffa342501aa71a2e853d835b 316 SUPERFAMILY SSF53300 85 275 1.08E-35 T 22-04-2016 IPR002035 von Willebrand factor, type A TOLA_RS08750 b270ecdbffa342501aa71a2e853d835b 316 PANTHER PTHR22550 1 314 4.8E-94 T 22-04-2016 TOLA_RS08750 b270ecdbffa342501aa71a2e853d835b 316 Gene3D G3DSA:3.40.50.410 87 275 4.8E-26 T 22-04-2016 IPR002035 von Willebrand factor, type A TOLA_RS08750 b270ecdbffa342501aa71a2e853d835b 316 Pfam PF00092 von Willebrand factor type A domain 88 274 1.1E-25 T 22-04-2016 IPR002035 von Willebrand factor, type A TOLA_RS03595 cec367c9bbb300c637f66b57d20fa379 248 PIRSF PIRSF034653 1 248 3.3E-119 T 22-04-2016 IPR017031 Predicted S-adenosyl-L-methionine dependent methyltransferase, YjhP-type TOLA_RS03595 cec367c9bbb300c637f66b57d20fa379 248 Pfam PF13847 Methyltransferase domain 36 157 5.3E-11 T 22-04-2016 IPR025714 Methyltransferase domain TOLA_RS03595 cec367c9bbb300c637f66b57d20fa379 248 Gene3D G3DSA:3.40.50.150 10 246 7.5E-50 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS03595 cec367c9bbb300c637f66b57d20fa379 248 SUPERFAMILY SSF53335 5 247 2.3E-45 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS03595 cec367c9bbb300c637f66b57d20fa379 248 PANTHER PTHR10108 21 148 2.1E-65 T 22-04-2016 TOLA_RS03595 cec367c9bbb300c637f66b57d20fa379 248 PANTHER PTHR10108 174 248 2.1E-65 T 22-04-2016 TOLA_RS03595 cec367c9bbb300c637f66b57d20fa379 248 PANTHER PTHR10108:SF893 21 148 2.1E-65 T 22-04-2016 TOLA_RS03595 cec367c9bbb300c637f66b57d20fa379 248 PANTHER PTHR10108:SF893 174 248 2.1E-65 T 22-04-2016 TOLA_RS12720 489eb377f8c28fc62450cf7d8ec0b0a8 76 TIGRFAM TIGR00165 S18: ribosomal protein bS18 4 72 4.1E-37 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12720 489eb377f8c28fc62450cf7d8ec0b0a8 76 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 72 5.0E-22 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12720 489eb377f8c28fc62450cf7d8ec0b0a8 76 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 1.0E-18 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12720 489eb377f8c28fc62450cf7d8ec0b0a8 76 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 1.0E-18 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12720 489eb377f8c28fc62450cf7d8ec0b0a8 76 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 1.0E-18 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12720 489eb377f8c28fc62450cf7d8ec0b0a8 76 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 1.0E-18 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12720 489eb377f8c28fc62450cf7d8ec0b0a8 76 PANTHER PTHR13479 3 72 4.6E-31 T 22-04-2016 TOLA_RS12720 489eb377f8c28fc62450cf7d8ec0b0a8 76 Pfam PF01084 Ribosomal protein S18 19 68 2.4E-25 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12720 489eb377f8c28fc62450cf7d8ec0b0a8 76 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 22-04-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12720 489eb377f8c28fc62450cf7d8ec0b0a8 76 Gene3D G3DSA:4.10.640.10 8 73 1.0E-31 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12720 489eb377f8c28fc62450cf7d8ec0b0a8 76 SUPERFAMILY SSF46911 3 72 3.01E-28 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12720 489eb377f8c28fc62450cf7d8ec0b0a8 76 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 20.898 T 22-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS04820 78d20e478d824e892e2ed35be8c1652e 268 Gene3D G3DSA:3.20.20.70 1 266 7.1E-93 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS04820 78d20e478d824e892e2ed35be8c1652e 268 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 22-04-2016 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 TOLA_RS04820 78d20e478d824e892e2ed35be8c1652e 268 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 263 5.4E-97 T 22-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 TOLA_RS04820 78d20e478d824e892e2ed35be8c1652e 268 SUPERFAMILY SSF51366 1 266 3.11E-87 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TOLA_RS04820 78d20e478d824e892e2ed35be8c1652e 268 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 265 36.702 T 22-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 TOLA_RS04820 78d20e478d824e892e2ed35be8c1652e 268 Pfam PF00290 Tryptophan synthase alpha chain 8 266 6.3E-92 T 22-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 TOLA_RS15355 380d073b009124a791123d267a038a85 279 Pfam PF01261 Xylose isomerase-like TIM barrel 19 238 2.3E-38 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS15355 380d073b009124a791123d267a038a85 279 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 279 42.294 T 22-04-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TOLA_RS15355 380d073b009124a791123d267a038a85 279 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 215 231 - T 22-04-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 TOLA_RS15355 380d073b009124a791123d267a038a85 279 PANTHER PTHR21445:SF0 1 278 9.0E-146 T 22-04-2016 TOLA_RS15355 380d073b009124a791123d267a038a85 279 Gene3D G3DSA:3.20.20.150 1 278 1.4E-115 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS15355 380d073b009124a791123d267a038a85 279 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 2 277 6.2E-106 T 22-04-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TOLA_RS15355 380d073b009124a791123d267a038a85 279 SUPERFAMILY SSF51658 1 278 2.49E-98 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS15355 380d073b009124a791123d267a038a85 279 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 22-04-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 TOLA_RS15355 380d073b009124a791123d267a038a85 279 PANTHER PTHR21445 1 278 9.0E-146 T 22-04-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TOLA_RS15355 380d073b009124a791123d267a038a85 279 SMART SM00518 3 279 1.5E-121 T 22-04-2016 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TOLA_RS15355 380d073b009124a791123d267a038a85 279 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 22-04-2016 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 TOLA_RS09385 3fbe38f88b8e432878a7a7c9a21b1aca 542 Gene3D G3DSA:3.40.720.10 289 486 3.6E-14 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 TOLA_RS09385 3fbe38f88b8e432878a7a7c9a21b1aca 542 Pfam PF08019 Domain of unknown function (DUF1705) 55 205 2.6E-46 T 22-04-2016 IPR012549 Domain of unknown function DUF1705 GO:0016021 TOLA_RS09385 3fbe38f88b8e432878a7a7c9a21b1aca 542 PANTHER PTHR30443 1 540 4.2E-238 T 22-04-2016 TOLA_RS09385 3fbe38f88b8e432878a7a7c9a21b1aca 542 Pfam PF00884 Sulfatase 233 522 2.2E-48 T 22-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 TOLA_RS09385 3fbe38f88b8e432878a7a7c9a21b1aca 542 PANTHER PTHR30443:SF0 1 540 4.2E-238 T 22-04-2016 TOLA_RS09385 3fbe38f88b8e432878a7a7c9a21b1aca 542 SUPERFAMILY SSF53649 275 486 1.87E-20 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 TOLA_RS11800 5207490cf1fbe0b53cc846de35ceb4e1 104 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 22 100 4.2E-36 T 22-04-2016 IPR003769 Adaptor protein ClpS, core GO:0030163 TOLA_RS11800 5207490cf1fbe0b53cc846de35ceb4e1 104 Gene3D G3DSA:3.30.1390.10 7 104 5.8E-46 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TOLA_RS11800 5207490cf1fbe0b53cc846de35ceb4e1 104 PANTHER PTHR33473 15 104 7.5E-41 T 22-04-2016 TOLA_RS11800 5207490cf1fbe0b53cc846de35ceb4e1 104 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 7 99 29.637 T 22-04-2016 IPR022935 ATP-dependent Clp protease adaptor protein ClpS TOLA_RS11800 5207490cf1fbe0b53cc846de35ceb4e1 104 SUPERFAMILY SSF54736 19 103 9.42E-35 T 22-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TOLA_RS06380 7561b1a71b324e7800b4dd948bbf3f88 146 Pfam PF03652 Holliday junction resolvase 9 139 3.3E-41 T 22-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TOLA_RS06380 7561b1a71b324e7800b4dd948bbf3f88 146 PANTHER PTHR33317 9 140 2.3E-42 T 22-04-2016 TOLA_RS06380 7561b1a71b324e7800b4dd948bbf3f88 146 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 10 139 3.1E-52 T 22-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TOLA_RS06380 7561b1a71b324e7800b4dd948bbf3f88 146 Gene3D G3DSA:3.30.420.140 8 141 1.8E-45 T 22-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 TOLA_RS06380 7561b1a71b324e7800b4dd948bbf3f88 146 SUPERFAMILY SSF53098 8 140 6.07E-42 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS06380 7561b1a71b324e7800b4dd948bbf3f88 146 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 7 142 25.683 T 22-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TOLA_RS06380 7561b1a71b324e7800b4dd948bbf3f88 146 SMART SM00732 7 107 2.8E-37 T 22-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 Gene3D G3DSA:3.20.20.80 146 569 1.1E-104 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 PANTHER PTHR10357:SF74 6 573 1.1E-261 T 22-04-2016 TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 PANTHER PTHR10357:SF74 603 654 1.1E-261 T 22-04-2016 TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 14 101 1.1E-18 T 22-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 10 656 5.2E-263 T 22-04-2016 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 UniPathway: UPA00165 TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 SUPERFAMILY SSF81296 10 140 1.96E-44 T 22-04-2016 IPR014756 Immunoglobulin E-set TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 SUPERFAMILY SSF51445 127 465 1.99E-123 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 SUPERFAMILY SSF51445 494 568 1.99E-123 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 SUPERFAMILY SSF51011 586 663 2.01E-17 T 22-04-2016 TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 Pfam PF00128 Alpha amylase, catalytic domain 182 345 2.0E-12 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 PANTHER PTHR10357 6 573 1.1E-261 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 PANTHER PTHR10357 603 654 1.1E-261 T 22-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 SMART SM00642 152 562 5.1E-7 T 22-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 Gene3D G3DSA:2.60.40.10 10 145 2.9E-49 T 22-04-2016 IPR013783 Immunoglobulin-like fold TOLA_RS13715 fd9030e34ad9e78e9b0822a1084b0796 695 Gene3D G3DSA:2.60.40.1180 586 661 1.8E-18 T 22-04-2016 IPR013780 Glycosyl hydrolase, all-beta TOLA_RS08005 7c3c5fd743aba7940526c37627a85506 320 Gene3D G3DSA:3.30.360.10 139 297 5.9E-23 T 22-04-2016 TOLA_RS08005 7c3c5fd743aba7940526c37627a85506 320 SUPERFAMILY SSF55347 128 300 8.0E-24 T 22-04-2016 TOLA_RS08005 7c3c5fd743aba7940526c37627a85506 320 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 136 299 6.1E-10 T 22-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 TOLA_RS08005 7c3c5fd743aba7940526c37627a85506 320 SUPERFAMILY SSF51735 3 150 1.13E-8 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS08005 7c3c5fd743aba7940526c37627a85506 320 Gene3D G3DSA:3.40.50.720 1 138 2.1E-14 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS06500 ad3df05f8d047008506b3ab0f3b0e975 159 Gene3D G3DSA:3.40.630.30 1 147 7.6E-20 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS06500 ad3df05f8d047008506b3ab0f3b0e975 159 Pfam PF00583 Acetyltransferase (GNAT) family 51 137 9.9E-9 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS06500 ad3df05f8d047008506b3ab0f3b0e975 159 SUPERFAMILY SSF55729 1 159 1.22E-21 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS07715 64d70b81fc4b5289252037b286769be7 374 Pfam PF13406 Transglycosylase SLT domain 60 354 6.5E-89 T 22-04-2016 IPR031304 Transglycosylase SLT domain 2 TOLA_RS07715 64d70b81fc4b5289252037b286769be7 374 SUPERFAMILY SSF53955 56 359 1.01E-89 T 22-04-2016 IPR023346 Lysozyme-like domain TOLA_RS07715 64d70b81fc4b5289252037b286769be7 374 PANTHER PTHR30163:SF0 1 360 8.4E-164 T 22-04-2016 TOLA_RS07715 64d70b81fc4b5289252037b286769be7 374 PANTHER PTHR30163 1 360 8.4E-164 T 22-04-2016 IPR011757 Lytic transglycosylase MltB TOLA_RS07715 64d70b81fc4b5289252037b286769be7 374 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 65 357 8.4E-115 T 22-04-2016 IPR011757 Lytic transglycosylase MltB TOLA_RS07715 64d70b81fc4b5289252037b286769be7 374 Gene3D G3DSA:1.10.530.10 249 360 1.1E-54 T 22-04-2016 TOLA_RS07715 64d70b81fc4b5289252037b286769be7 374 Gene3D G3DSA:1.10.530.10 115 168 1.1E-54 T 22-04-2016 TOLA_RS03145 1649090da6c0df33debe4f581671c1e0 365 Gene3D G3DSA:3.40.50.2000 229 299 1.5E-5 T 22-04-2016 TOLA_RS03145 1649090da6c0df33debe4f581671c1e0 365 SUPERFAMILY SSF53756 1 321 1.06E-13 T 22-04-2016 TOLA_RS03145 1649090da6c0df33debe4f581671c1e0 365 Pfam PF13528 Glycosyl transferase family 1 1 299 2.4E-40 T 22-04-2016 TOLA_RS03145 1649090da6c0df33debe4f581671c1e0 365 Gene3D G3DSA:3.40.50.2000 9 167 2.1E-5 T 22-04-2016 TOLA_RS03145 1649090da6c0df33debe4f581671c1e0 365 TIGRFAM TIGR00661 MJ1255: conserved hypothetical protein 2 310 8.5E-78 T 22-04-2016 IPR005262 Conserved hypothetical protein CHP00661 KEGG: 00540+2.4.-.- TOLA_RS01945 ae16ce2bac2bd49343c52527b9e9ed1f 282 TIGRFAM TIGR01713 typeII_sec_gspC: type II secretion system protein C 22 279 6.8E-65 T 22-04-2016 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 TOLA_RS01945 ae16ce2bac2bd49343c52527b9e9ed1f 282 Pfam PF11356 Type II secretion system protein C 25 163 9.3E-31 T 22-04-2016 IPR024961 Type II secretion system protein C, N-terminal TOLA_RS01945 ae16ce2bac2bd49343c52527b9e9ed1f 282 ProSitePatterns PS01141 Bacterial type II secretion system protein C signature. 217 243 - T 22-04-2016 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 TOLA_RS01945 ae16ce2bac2bd49343c52527b9e9ed1f 282 Gene3D G3DSA:2.30.42.10 226 277 9.0E-7 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS01945 ae16ce2bac2bd49343c52527b9e9ed1f 282 PRINTS PR00810 Bacterial general secretion pathway protein C signature 233 243 8.9E-6 T 22-04-2016 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 TOLA_RS01945 ae16ce2bac2bd49343c52527b9e9ed1f 282 PRINTS PR00810 Bacterial general secretion pathway protein C signature 100 109 8.9E-6 T 22-04-2016 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 TOLA_RS01945 ae16ce2bac2bd49343c52527b9e9ed1f 282 SUPERFAMILY SSF50156 184 278 1.73E-16 T 22-04-2016 IPR001478 PDZ domain GO:0005515 TOLA_RS03530 0f1a8c5a95503d6af2f60236708e8d74 402 Pfam PF04230 Polysaccharide pyruvyl transferase 157 329 1.4E-16 T 22-04-2016 IPR007345 Polysaccharide pyruvyl transferase TOLA_RS10680 1ecb3b23cf906f806a4f105cc8537977 151 Pfam PF07977 FabA-like domain 17 144 6.1E-41 T 22-04-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 TOLA_RS10680 1ecb3b23cf906f806a4f105cc8537977 151 PANTHER PTHR30272 3 151 2.2E-79 T 22-04-2016 TOLA_RS10680 1ecb3b23cf906f806a4f105cc8537977 151 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 8 149 6.4E-60 T 22-04-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 TOLA_RS10680 1ecb3b23cf906f806a4f105cc8537977 151 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 8 151 35.465 T 22-04-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 TOLA_RS10680 1ecb3b23cf906f806a4f105cc8537977 151 Gene3D G3DSA:3.10.129.10 3 149 5.3E-60 T 22-04-2016 IPR029069 HotDog domain TOLA_RS10680 1ecb3b23cf906f806a4f105cc8537977 151 SUPERFAMILY SSF54637 7 149 3.48E-50 T 22-04-2016 IPR029069 HotDog domain TOLA_RS02085 6dba6afee5fcc7178c1885a7a6db2e01 559 SUPERFAMILY SSF52091 438 543 5.49E-20 T 22-04-2016 IPR002645 STAS domain TOLA_RS02085 6dba6afee5fcc7178c1885a7a6db2e01 559 PANTHER PTHR11814:SF112 16 559 8.3E-250 T 22-04-2016 TOLA_RS02085 6dba6afee5fcc7178c1885a7a6db2e01 559 PANTHER PTHR11814 16 559 8.3E-250 T 22-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 TOLA_RS02085 6dba6afee5fcc7178c1885a7a6db2e01 559 Pfam PF01740 STAS domain 439 539 5.8E-19 T 22-04-2016 IPR002645 STAS domain TOLA_RS02085 6dba6afee5fcc7178c1885a7a6db2e01 559 Pfam PF00916 Sulfate permease family 21 384 6.9E-93 T 22-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 TOLA_RS02085 6dba6afee5fcc7178c1885a7a6db2e01 559 TIGRFAM TIGR00815 sulP: sulfate permease 18 539 1.4E-114 T 22-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 TOLA_RS02085 6dba6afee5fcc7178c1885a7a6db2e01 559 Gene3D G3DSA:3.30.750.24 438 544 7.5E-19 T 22-04-2016 IPR002645 STAS domain TOLA_RS07075 f8e19dc6b63a907d8114a4cbf622b01b 188 SUPERFAMILY SSF55811 27 180 4.87E-30 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS07075 f8e19dc6b63a907d8114a4cbf622b01b 188 Pfam PF00293 NUDIX domain 29 142 1.4E-12 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TOLA_RS07075 f8e19dc6b63a907d8114a4cbf622b01b 188 ProSitePatterns PS01293 Nudix CoA signature. 46 66 - T 22-04-2016 IPR000059 NUDIX hydrolase, NudL, conserved site GO:0000287|GO:0009132|GO:0016818|GO:0030145 TOLA_RS07075 f8e19dc6b63a907d8114a4cbf622b01b 188 PANTHER PTHR12992 25 185 4.5E-46 T 22-04-2016 TOLA_RS07075 f8e19dc6b63a907d8114a4cbf622b01b 188 Gene3D G3DSA:3.90.79.10 21 185 1.1E-36 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS01820 9f811f5cd917bc8abd9029a631e99862 418 Pfam PF00375 Sodium:dicarboxylate symporter family 17 396 7.8E-61 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01820 9f811f5cd917bc8abd9029a631e99862 418 Gene3D G3DSA:1.10.3860.10 11 399 1.1E-80 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01820 9f811f5cd917bc8abd9029a631e99862 418 SUPERFAMILY SSF118215 17 398 1.57E-92 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01820 9f811f5cd917bc8abd9029a631e99862 418 PRINTS PR00173 Glutamate-aspartate symporter signature 324 343 1.9E-14 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01820 9f811f5cd917bc8abd9029a631e99862 418 PRINTS PR00173 Glutamate-aspartate symporter signature 187 206 1.9E-14 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01820 9f811f5cd917bc8abd9029a631e99862 418 PRINTS PR00173 Glutamate-aspartate symporter signature 289 315 1.9E-14 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01820 9f811f5cd917bc8abd9029a631e99862 418 PRINTS PR00173 Glutamate-aspartate symporter signature 15 35 1.9E-14 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01820 9f811f5cd917bc8abd9029a631e99862 418 PANTHER PTHR11958:SF68 7 418 1.9E-232 T 22-04-2016 TOLA_RS01820 9f811f5cd917bc8abd9029a631e99862 418 PANTHER PTHR11958 7 418 1.9E-232 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01820 9f811f5cd917bc8abd9029a631e99862 418 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 5 406 36.22 T 22-04-2016 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 TOLA_RS00440 c953f3975264e23db6a7d2da8b46f198 99 Gene3D G3DSA:3.30.70.860 28 96 1.4E-12 T 22-04-2016 TOLA_RS00440 c953f3975264e23db6a7d2da8b46f198 99 PANTHER PTHR38769 1 99 2.6E-14 T 22-04-2016 TOLA_RS00440 c953f3975264e23db6a7d2da8b46f198 99 Pfam PF04175 Protein of unknown function (DUF406) 8 96 1.7E-28 T 22-04-2016 IPR005272 Conserved hypothetical protein CHP00743 TOLA_RS00440 c953f3975264e23db6a7d2da8b46f198 99 PANTHER PTHR38769:SF1 1 99 2.6E-14 T 22-04-2016 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 PANTHER PTHR30222 20 324 6.4E-50 T 22-04-2016 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 Gene3D G3DSA:3.40.190.10 19 120 7.0E-23 T 22-04-2016 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 Gene3D G3DSA:3.40.190.10 265 303 7.0E-23 T 22-04-2016 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 241 260 1.3E-18 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 24 40 1.3E-18 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 40 61 1.3E-18 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 111 127 1.3E-18 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 284 310 1.3E-18 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 175 1.3E-18 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 PANTHER PTHR30222:SF5 20 324 6.4E-50 T 22-04-2016 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 Gene3D G3DSA:3.40.190.10 121 264 3.0E-37 T 22-04-2016 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 SUPERFAMILY SSF53850 20 324 1.47E-59 T 22-04-2016 TOLA_RS00025 7ba2fa50fb8546fbe77b481a19c96e1a 337 Pfam PF13416 Bacterial extracellular solute-binding protein 35 303 4.1E-26 T 22-04-2016 TOLA_RS06810 1279d0141d46b8bfd0fbdba795f598d1 302 Gene3D G3DSA:3.30.420.40 103 296 4.8E-53 T 22-04-2016 TOLA_RS06810 1279d0141d46b8bfd0fbdba795f598d1 302 PANTHER PTHR18964:SF121 1 161 7.3E-54 T 22-04-2016 TOLA_RS06810 1279d0141d46b8bfd0fbdba795f598d1 302 PANTHER PTHR18964:SF121 179 298 7.3E-54 T 22-04-2016 TOLA_RS06810 1279d0141d46b8bfd0fbdba795f598d1 302 PANTHER PTHR18964 1 161 7.3E-54 T 22-04-2016 TOLA_RS06810 1279d0141d46b8bfd0fbdba795f598d1 302 PANTHER PTHR18964 179 298 7.3E-54 T 22-04-2016 TOLA_RS06810 1279d0141d46b8bfd0fbdba795f598d1 302 Gene3D G3DSA:3.30.420.40 1 102 1.4E-24 T 22-04-2016 TOLA_RS06810 1279d0141d46b8bfd0fbdba795f598d1 302 Pfam PF00480 ROK family 4 290 1.3E-40 T 22-04-2016 IPR000600 ROK family TOLA_RS06810 1279d0141d46b8bfd0fbdba795f598d1 302 SUPERFAMILY SSF53067 1 297 7.69E-51 T 22-04-2016 TOLA_RS01010 3ceb84e0d3f8caf62499ab4ea44e9426 329 PANTHER PTHR10799 3 148 5.8E-12 T 22-04-2016 TOLA_RS01010 3ceb84e0d3f8caf62499ab4ea44e9426 329 Pfam PF00990 Diguanylate cyclase, GGDEF domain 159 315 5.0E-31 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS01010 3ceb84e0d3f8caf62499ab4ea44e9426 329 PANTHER PTHR10799:SF750 3 148 5.8E-12 T 22-04-2016 TOLA_RS01010 3ceb84e0d3f8caf62499ab4ea44e9426 329 Gene3D G3DSA:3.30.70.270 161 320 1.2E-37 T 22-04-2016 TOLA_RS01010 3ceb84e0d3f8caf62499ab4ea44e9426 329 SUPERFAMILY SSF55073 164 318 1.1E-33 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS01010 3ceb84e0d3f8caf62499ab4ea44e9426 329 SMART SM00267 148 319 5.7E-29 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS01010 3ceb84e0d3f8caf62499ab4ea44e9426 329 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 158 318 4.8E-31 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS01010 3ceb84e0d3f8caf62499ab4ea44e9426 329 PANTHER PTHR10799 192 322 5.8E-12 T 22-04-2016 TOLA_RS01010 3ceb84e0d3f8caf62499ab4ea44e9426 329 PANTHER PTHR10799:SF750 192 322 5.8E-12 T 22-04-2016 TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 Pfam PF16188 C-terminal region of peptidase_M24 539 597 2.7E-19 T 22-04-2016 IPR032416 Peptidase M24, C-terminal domain TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 Pfam PF16189 Creatinase/Prolidase N-terminal domain 151 311 8.2E-34 T 22-04-2016 TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 SUPERFAMILY SSF53092 8 135 7.32E-17 T 22-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 Pfam PF00557 Metallopeptidase family M24 314 528 2.4E-44 T 22-04-2016 IPR000994 Peptidase M24, structural domain TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 SUPERFAMILY SSF55920 308 563 1.28E-55 T 22-04-2016 IPR000994 Peptidase M24, structural domain TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 PANTHER PTHR10804:SF105 287 595 4.0E-205 T 22-04-2016 TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 PANTHER PTHR10804:SF105 6 183 4.0E-205 T 22-04-2016 TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 PANTHER PTHR10804 287 595 4.0E-205 T 22-04-2016 TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 PANTHER PTHR10804 6 183 4.0E-205 T 22-04-2016 TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 Pfam PF01321 Creatinase/Prolidase N-terminal domain 10 141 2.7E-19 T 22-04-2016 IPR000587 Creatinase, N-terminal GO:0016787 TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 Gene3D G3DSA:3.40.350.10 175 289 7.5E-5 T 22-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 Gene3D G3DSA:3.40.350.10 8 138 6.8E-23 T 22-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TOLA_RS15410 26cb9eaddbec629f459bb301eacd0447 597 Gene3D G3DSA:3.90.230.10 306 564 1.9E-57 T 22-04-2016 IPR000994 Peptidase M24, structural domain TOLA_RS11675 67e156c93b9d40d76411c37ae10c4a3f 161 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 134 8.5E-37 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS11675 67e156c93b9d40d76411c37ae10c4a3f 161 PANTHER PTHR20941:SF10 1 159 1.4E-69 T 22-04-2016 TOLA_RS11675 67e156c93b9d40d76411c37ae10c4a3f 161 PANTHER PTHR20941 1 159 1.4E-69 T 22-04-2016 TOLA_RS11675 67e156c93b9d40d76411c37ae10c4a3f 161 Gene3D G3DSA:3.30.70.560 3 154 4.3E-57 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS11675 67e156c93b9d40d76411c37ae10c4a3f 161 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS11675 67e156c93b9d40d76411c37ae10c4a3f 161 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 134 7.6E-44 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS11675 67e156c93b9d40d76411c37ae10c4a3f 161 SUPERFAMILY SSF55083 1 156 3.66E-53 T 22-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS15985 8142ce331f45642bdd228e3c9ab27b43 432 PANTHER PTHR37419:SF3 4 430 1.5E-126 T 22-04-2016 TOLA_RS15985 8142ce331f45642bdd228e3c9ab27b43 432 PANTHER PTHR37419 4 430 1.5E-126 T 22-04-2016 TOLA_RS15985 8142ce331f45642bdd228e3c9ab27b43 432 Pfam PF07805 HipA-like N-terminal domain 150 236 6.7E-21 T 22-04-2016 IPR012894 HipA, N-terminal subdomain 2 TOLA_RS15985 8142ce331f45642bdd228e3c9ab27b43 432 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 3 103 5.1E-32 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 TOLA_RS15985 8142ce331f45642bdd228e3c9ab27b43 432 Pfam PF07804 HipA-like C-terminal domain 247 399 1.8E-31 T 22-04-2016 IPR012893 HipA-like, C-terminal TOLA_RS15985 8142ce331f45642bdd228e3c9ab27b43 432 Pfam PF13657 HipA N-terminal domain 4 103 3.7E-26 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 TOLA_RS02455 9b79963ffe0d9f750d2147d2fd61d676 194 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 3 108 1.1E-10 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 TOLA_RS02455 9b79963ffe0d9f750d2147d2fd61d676 194 SMART SM00464 2 186 0.0024 T 22-04-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 TOLA_RS02455 9b79963ffe0d9f750d2147d2fd61d676 194 SUPERFAMILY SSF88697 1 184 1.32E-41 T 22-04-2016 IPR015947 PUA-like domain TOLA_RS10630 618265f3add2e00cfb02fd4346c1553d 273 SMART SM00880 16 271 5.0E-16 T 22-04-2016 IPR007899 CHAD domain TOLA_RS10630 618265f3add2e00cfb02fd4346c1553d 273 Pfam PF05235 CHAD domain 18 234 2.8E-23 T 22-04-2016 IPR007899 CHAD domain TOLA_RS14855 551815f7347dc1a72ea260c10f9acccf 212 PANTHER PTHR31527 7 212 1.1E-58 T 22-04-2016 TOLA_RS14855 551815f7347dc1a72ea260c10f9acccf 212 PANTHER PTHR31527:SF0 7 212 1.1E-58 T 22-04-2016 TOLA_RS14855 551815f7347dc1a72ea260c10f9acccf 212 TIGRFAM TIGR03424 urea_degr_1: urea carboxylase-associated protein 1 12 211 3.5E-102 T 22-04-2016 IPR017791 Urea carboxylase-associated protein 1 TOLA_RS14855 551815f7347dc1a72ea260c10f9acccf 212 Pfam PF09347 Domain of unknown function (DUF1989) 16 185 2.0E-65 T 22-04-2016 IPR018959 Domain of unknown function DUF1989 TOLA_RS06365 c55d0a69ee756db41a106bf13e94b48a 414 PANTHER PTHR30489 1 414 1.7E-42 T 22-04-2016 TOLA_RS06365 c55d0a69ee756db41a106bf13e94b48a 414 Pfam PF02687 FtsX-like permease family 287 407 4.6E-19 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 TOLA_RS06365 c55d0a69ee756db41a106bf13e94b48a 414 Pfam PF12704 MacB-like periplasmic core domain 19 244 4.9E-10 T 22-04-2016 IPR025857 MacB-like periplasmic core domain TOLA_RS08185 7c384ab9925944af10929b58d07fe84a 251 SUPERFAMILY SSF52540 66 239 2.79E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08185 7c384ab9925944af10929b58d07fe84a 251 PIRSF PIRSF003073 1 250 3.2E-71 T 22-04-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein TOLA_RS08185 7c384ab9925944af10929b58d07fe84a 251 PANTHER PTHR30050 8 240 9.0E-68 T 22-04-2016 TOLA_RS08185 7c384ab9925944af10929b58d07fe84a 251 PANTHER PTHR30050:SF6 8 240 9.0E-68 T 22-04-2016 TOLA_RS08185 7c384ab9925944af10929b58d07fe84a 251 Pfam PF01695 IstB-like ATP binding protein 54 229 2.4E-60 T 22-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 TOLA_RS08185 7c384ab9925944af10929b58d07fe84a 251 Gene3D G3DSA:3.40.50.300 52 230 1.3E-27 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08185 7c384ab9925944af10929b58d07fe84a 251 Pfam PF08483 IstB-like ATP binding N-terminal 24 52 1.2E-10 T 22-04-2016 IPR013690 IstB-like ATP binding N-terminal TOLA_RS01980 942158e795253b9e9af9b7ccd0115b92 367 SUPERFAMILY SSF53335 11 366 1.72E-47 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS01980 942158e795253b9e9af9b7ccd0115b92 367 PANTHER PTHR11061:SF25 11 367 4.0E-202 T 22-04-2016 TOLA_RS01980 942158e795253b9e9af9b7ccd0115b92 367 TIGRFAM TIGR02143 trmA_only: tRNA (uracil(54)-C(5))-methyltransferase 11 367 3.8E-176 T 22-04-2016 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 TOLA_RS01980 942158e795253b9e9af9b7ccd0115b92 367 PANTHER PTHR11061 11 367 4.0E-202 T 22-04-2016 TOLA_RS01980 942158e795253b9e9af9b7ccd0115b92 367 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 300 329 - T 22-04-2016 IPR030390 RNA methyltransferase TrmA, active site TOLA_RS01980 942158e795253b9e9af9b7ccd0115b92 367 Gene3D G3DSA:3.40.50.150 157 365 2.5E-40 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS01980 942158e795253b9e9af9b7ccd0115b92 367 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 11 367 2.9E-175 T 22-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TOLA_RS01980 942158e795253b9e9af9b7ccd0115b92 367 Hamap MF_01011 tRNA/tmRNA (uracil-C(5))-methyltransferase [trmA]. 4 367 43.303 T 22-04-2016 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 TOLA_RS05895 0962fceb824c847c5fceb9be7e27f2f0 254 SUPERFAMILY SSF49899 34 224 9.5E-6 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain TOLA_RS12895 669a0825c5e7189ed41167d8c43b1f2e 322 SUPERFAMILY SSF51395 11 318 4.58E-88 T 22-04-2016 TOLA_RS12895 669a0825c5e7189ed41167d8c43b1f2e 322 PIRSF PIRSF006621 1 322 1.0E-101 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TOLA_RS12895 669a0825c5e7189ed41167d8c43b1f2e 322 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 319 2.4E-127 T 22-04-2016 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 TOLA_RS12895 669a0825c5e7189ed41167d8c43b1f2e 322 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 22-04-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 TOLA_RS12895 669a0825c5e7189ed41167d8c43b1f2e 322 Gene3D G3DSA:1.10.1200.80 255 319 5.5E-18 T 22-04-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 TOLA_RS12895 669a0825c5e7189ed41167d8c43b1f2e 322 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 321 48.074 T 22-04-2016 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 TOLA_RS12895 669a0825c5e7189ed41167d8c43b1f2e 322 Pfam PF01207 Dihydrouridine synthase (Dus) 13 317 5.9E-107 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TOLA_RS12895 669a0825c5e7189ed41167d8c43b1f2e 322 PANTHER PTHR11082 1 317 1.1E-139 T 22-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TOLA_RS12895 669a0825c5e7189ed41167d8c43b1f2e 322 PANTHER PTHR11082:SF25 1 317 1.1E-139 T 22-04-2016 TOLA_RS12895 669a0825c5e7189ed41167d8c43b1f2e 322 Gene3D G3DSA:3.20.20.70 8 243 7.4E-81 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS12030 718b073c35eed0909f3bfe1b117e6f1f 327 PANTHER PTHR33540:SF1 11 321 2.0E-92 T 22-04-2016 TOLA_RS12030 718b073c35eed0909f3bfe1b117e6f1f 327 Gene3D G3DSA:3.90.1200.10 89 321 2.6E-60 T 22-04-2016 TOLA_RS12030 718b073c35eed0909f3bfe1b117e6f1f 327 SUPERFAMILY SSF56112 7 300 3.59E-48 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS12030 718b073c35eed0909f3bfe1b117e6f1f 327 Pfam PF01636 Phosphotransferase enzyme family 23 237 1.1E-23 T 22-04-2016 IPR002575 Aminoglycoside phosphotransferase TOLA_RS12030 718b073c35eed0909f3bfe1b117e6f1f 327 Gene3D G3DSA:3.30.200.20 1 87 2.7E-21 T 22-04-2016 TOLA_RS12030 718b073c35eed0909f3bfe1b117e6f1f 327 PANTHER PTHR33540 11 321 2.0E-92 T 22-04-2016 TOLA_RS08720 ca03dfdf7a3f2f5bec9fe2fde0c5612b 338 SMART SM00342 255 336 8.6E-20 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS08720 ca03dfdf7a3f2f5bec9fe2fde0c5612b 338 Gene3D G3DSA:1.10.10.60 293 337 1.3E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS08720 ca03dfdf7a3f2f5bec9fe2fde0c5612b 338 Pfam PF12833 Helix-turn-helix domain 260 337 5.0E-17 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS08720 ca03dfdf7a3f2f5bec9fe2fde0c5612b 338 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 290 332 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TOLA_RS08720 ca03dfdf7a3f2f5bec9fe2fde0c5612b 338 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 305 320 1.1E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS08720 ca03dfdf7a3f2f5bec9fe2fde0c5612b 338 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 320 336 1.1E-5 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS08720 ca03dfdf7a3f2f5bec9fe2fde0c5612b 338 PANTHER PTHR11019 256 338 1.3E-18 T 22-04-2016 TOLA_RS08720 ca03dfdf7a3f2f5bec9fe2fde0c5612b 338 SUPERFAMILY SSF46689 290 337 5.83E-12 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS12200 8c160cdeb5ce40ba787b7c3200c93b73 578 SUPERFAMILY SSF110849 37 137 5.23E-9 T 22-04-2016 IPR003115 ParB/Sulfiredoxin TOLA_RS12200 8c160cdeb5ce40ba787b7c3200c93b73 578 Gene3D G3DSA:3.90.1530.10 34 102 1.1E-5 T 22-04-2016 TOLA_RS12200 8c160cdeb5ce40ba787b7c3200c93b73 578 Pfam PF02195 ParB-like nuclease domain 39 101 2.6E-4 T 22-04-2016 IPR003115 ParB/Sulfiredoxin TOLA_RS12200 8c160cdeb5ce40ba787b7c3200c93b73 578 TIGRFAM TIGR03764 ICE_PFGI_1_parB: integrating conjugative element, PFGI_1 class, ParB family protein 28 290 4.6E-115 T 22-04-2016 IPR022304 Integrating conjugative element, PFGI-1, ParB TOLA_RS15440 3b2fafd66c6e1ede2442c20855cc5a4d 292 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 11 290 33.951 T 22-04-2016 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 TOLA_RS15440 3b2fafd66c6e1ede2442c20855cc5a4d 292 SUPERFAMILY SSF53335 12 290 4.63E-77 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS15440 3b2fafd66c6e1ede2442c20855cc5a4d 292 PANTHER PTHR11558 13 289 1.2E-80 T 22-04-2016 TOLA_RS15440 3b2fafd66c6e1ede2442c20855cc5a4d 292 Pfam PF01564 Spermine/spermidine synthase 18 242 7.7E-55 T 22-04-2016 TOLA_RS15440 3b2fafd66c6e1ede2442c20855cc5a4d 292 Gene3D G3DSA:3.40.50.150 63 290 5.9E-67 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS15440 3b2fafd66c6e1ede2442c20855cc5a4d 292 Gene3D G3DSA:2.30.140.10 12 62 3.8E-15 T 22-04-2016 TOLA_RS05260 ee279454eeebfb77de1d185bf8888535 576 PANTHER PTHR37323:SF1 1 576 1.2E-92 T 22-04-2016 TOLA_RS05260 ee279454eeebfb77de1d185bf8888535 576 Gene3D G3DSA:3.40.630.30 317 442 1.3E-6 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS05260 ee279454eeebfb77de1d185bf8888535 576 SUPERFAMILY SSF55729 309 465 8.48E-25 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS05260 ee279454eeebfb77de1d185bf8888535 576 Gene3D G3DSA:3.40.1130.10 66 194 5.0E-4 T 22-04-2016 TOLA_RS05260 ee279454eeebfb77de1d185bf8888535 576 SMART SM00563 76 193 5.1E-7 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TOLA_RS05260 ee279454eeebfb77de1d185bf8888535 576 PANTHER PTHR37323 1 576 1.2E-92 T 22-04-2016 TOLA_RS05260 ee279454eeebfb77de1d185bf8888535 576 SUPERFAMILY SSF69593 62 257 3.4E-15 T 22-04-2016 TOLA_RS05260 ee279454eeebfb77de1d185bf8888535 576 Pfam PF13444 Acetyltransferase (GNAT) domain 321 422 1.5E-24 T 22-04-2016 TOLA_RS05260 ee279454eeebfb77de1d185bf8888535 576 Pfam PF01553 Acyltransferase 66 191 8.7E-11 T 22-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TOLA_RS09475 06b0ea06ba9b48325adccbd9a154c340 301 SUPERFAMILY SSF103481 191 287 8.76E-10 T 22-04-2016 TOLA_RS09475 06b0ea06ba9b48325adccbd9a154c340 301 Pfam PF00892 EamA-like transporter family 4 134 5.4E-13 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS09475 06b0ea06ba9b48325adccbd9a154c340 301 Pfam PF00892 EamA-like transporter family 150 283 6.9E-13 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS09475 06b0ea06ba9b48325adccbd9a154c340 301 PANTHER PTHR32322:SF8 1 280 1.8E-53 T 22-04-2016 TOLA_RS09475 06b0ea06ba9b48325adccbd9a154c340 301 PANTHER PTHR32322 1 280 1.8E-53 T 22-04-2016 TOLA_RS09475 06b0ea06ba9b48325adccbd9a154c340 301 SUPERFAMILY SSF103481 35 137 8.5E-14 T 22-04-2016 TOLA_RS11075 bb8d15d7ac611877a4656f45ff6ad135 174 Hamap MF_01042 UPF0115 protein YfcN [yfcN]. 1 172 38.899 T 22-04-2016 IPR022990 Uncharacterised protein family UPF0115 TOLA_RS11075 bb8d15d7ac611877a4656f45ff6ad135 174 SUPERFAMILY SSF160443 94 168 3.66E-11 T 22-04-2016 IPR002625 Smr domain TOLA_RS11075 bb8d15d7ac611877a4656f45ff6ad135 174 PANTHER PTHR35562:SF1 1 171 2.7E-95 T 22-04-2016 TOLA_RS11075 bb8d15d7ac611877a4656f45ff6ad135 174 Pfam PF01713 Smr domain 96 170 9.9E-20 T 22-04-2016 IPR002625 Smr domain TOLA_RS11075 bb8d15d7ac611877a4656f45ff6ad135 174 PANTHER PTHR35562 1 171 2.7E-95 T 22-04-2016 TOLA_RS11075 bb8d15d7ac611877a4656f45ff6ad135 174 SMART SM00463 93 171 4.9E-21 T 22-04-2016 IPR002625 Smr domain TOLA_RS02850 d8766fce2265cdccc552ef21c7066bf8 153 PANTHER PTHR38767 2 152 2.5E-44 T 22-04-2016 TOLA_RS02850 d8766fce2265cdccc552ef21c7066bf8 153 Gene3D G3DSA:3.40.50.10110 1 147 1.5E-48 T 22-04-2016 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 TOLA_RS02850 d8766fce2265cdccc552ef21c7066bf8 153 SUPERFAMILY SSF102400 1 147 5.1E-40 T 22-04-2016 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 TOLA_RS02850 d8766fce2265cdccc552ef21c7066bf8 153 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 144 1.2E-38 T 22-04-2016 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 136 155 7.62E-65 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 72 95 7.62E-65 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 52 70 7.62E-65 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 191 211 7.62E-65 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 304 330 7.62E-65 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 Gene3D G3DSA:3.30.420.40 10 163 8.8E-47 T 22-04-2016 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 Gene3D G3DSA:3.30.420.40 164 190 1.0E-33 T 22-04-2016 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 Gene3D G3DSA:3.30.420.40 267 321 1.0E-33 T 22-04-2016 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 PANTHER PTHR19375:SF117 9 330 1.7E-187 T 22-04-2016 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 Gene3D G3DSA:3.90.640.10 191 263 3.9E-31 T 22-04-2016 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 339 5.6E-167 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 Pfam PF06723 MreB/Mbl protein 11 338 2.8E-149 T 22-04-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 PANTHER PTHR19375 9 330 1.7E-187 T 22-04-2016 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 SUPERFAMILY SSF53067 153 339 6.65E-50 T 22-04-2016 TOLA_RS01340 aa1c8b1095356a26facec251c68fa31a 347 SUPERFAMILY SSF53067 9 152 7.37E-38 T 22-04-2016 TOLA_RS08285 7af6d2d34f444a0500cb37246e7df655 422 PANTHER PTHR30483:SF8 22 407 4.6E-201 T 22-04-2016 TOLA_RS08285 7af6d2d34f444a0500cb37246e7df655 422 SUPERFAMILY SSF53822 26 395 5.35E-93 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS08285 7af6d2d34f444a0500cb37246e7df655 422 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 27 391 1.8E-173 T 22-04-2016 IPR017777 ABC transporter, urea, substrate-binding, UrtA TOLA_RS08285 7af6d2d34f444a0500cb37246e7df655 422 Pfam PF13433 Periplasmic binding protein domain 27 394 1.1E-171 T 22-04-2016 TOLA_RS08285 7af6d2d34f444a0500cb37246e7df655 422 PANTHER PTHR30483 22 407 4.6E-201 T 22-04-2016 TOLA_RS08285 7af6d2d34f444a0500cb37246e7df655 422 Gene3D G3DSA:3.40.50.2300 142 332 1.9E-74 T 22-04-2016 TOLA_RS08285 7af6d2d34f444a0500cb37246e7df655 422 Gene3D G3DSA:3.40.50.2300 26 141 4.8E-4 T 22-04-2016 TOLA_RS09875 2efb7d6b6fa498dad06175e6e719eedd 323 PANTHER PTHR32196 21 321 1.2E-99 T 22-04-2016 TOLA_RS09875 2efb7d6b6fa498dad06175e6e719eedd 323 PANTHER PTHR32196:SF21 21 321 1.2E-99 T 22-04-2016 TOLA_RS09875 2efb7d6b6fa498dad06175e6e719eedd 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 49 314 3.1E-47 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS10750 6aa4eec4220a5c71511e25ce4afc4931 275 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 272 56.581 T 22-04-2016 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117|UniPathway: UPA00034 TOLA_RS10750 6aa4eec4220a5c71511e25ce4afc4931 275 Gene3D G3DSA:2.160.10.10 89 255 2.9E-60 T 22-04-2016 TOLA_RS10750 6aa4eec4220a5c71511e25ce4afc4931 275 PANTHER PTHR19136:SF52 13 273 3.3E-126 T 22-04-2016 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117|UniPathway: UPA00034 TOLA_RS10750 6aa4eec4220a5c71511e25ce4afc4931 275 Gene3D G3DSA:1.10.166.10 1 70 1.1E-31 T 22-04-2016 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117|UniPathway: UPA00034 TOLA_RS10750 6aa4eec4220a5c71511e25ce4afc4931 275 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 4 273 5.6E-147 T 22-04-2016 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117|UniPathway: UPA00034 TOLA_RS10750 6aa4eec4220a5c71511e25ce4afc4931 275 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 175 209 5.3E-13 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS10750 6aa4eec4220a5c71511e25ce4afc4931 275 PANTHER PTHR19136 13 273 3.3E-126 T 22-04-2016 TOLA_RS10750 6aa4eec4220a5c71511e25ce4afc4931 275 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 22-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 TOLA_RS10750 6aa4eec4220a5c71511e25ce4afc4931 275 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 166 1.3E-4 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS10750 6aa4eec4220a5c71511e25ce4afc4931 275 SUPERFAMILY SSF51161 2 256 1.94E-76 T 22-04-2016 IPR011004 Trimeric LpxA-like TOLA_RS10750 6aa4eec4220a5c71511e25ce4afc4931 275 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 3 69 4.7E-26 T 22-04-2016 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117|UniPathway: UPA00034 TOLA_RS08505 0db5bb454f7a5e1abf399c73c09d1acb 265 PANTHER PTHR36925 1 261 2.0E-72 T 22-04-2016 TOLA_RS08505 0db5bb454f7a5e1abf399c73c09d1acb 265 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 4 257 1.2E-57 T 22-04-2016 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 TOLA_RS08505 0db5bb454f7a5e1abf399c73c09d1acb 265 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 5 247 1.2E-74 T 22-04-2016 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 TOLA_RS08240 fb547f7edd8f76d9b631bbfc8f00f84e 188 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 143 22.528 T 22-04-2016 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 TOLA_RS08240 fb547f7edd8f76d9b631bbfc8f00f84e 188 SUPERFAMILY SSF69287 1 71 8.11E-14 T 22-04-2016 IPR004029 UreE urease accessory, N-terminal TOLA_RS08240 fb547f7edd8f76d9b631bbfc8f00f84e 188 Pfam PF02814 UreE urease accessory protein, N-terminal domain 20 68 1.0E-11 T 22-04-2016 IPR004029 UreE urease accessory, N-terminal TOLA_RS08240 fb547f7edd8f76d9b631bbfc8f00f84e 188 Gene3D G3DSA:3.30.70.790 76 146 6.1E-29 T 22-04-2016 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 TOLA_RS08240 fb547f7edd8f76d9b631bbfc8f00f84e 188 SMART SM00988 1 68 2.2E-15 T 22-04-2016 IPR004029 UreE urease accessory, N-terminal TOLA_RS08240 fb547f7edd8f76d9b631bbfc8f00f84e 188 Pfam PF05194 UreE urease accessory protein, C-terminal domain 76 165 5.9E-24 T 22-04-2016 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 TOLA_RS08240 fb547f7edd8f76d9b631bbfc8f00f84e 188 Gene3D G3DSA:2.60.260.20 1 75 1.1E-29 T 22-04-2016 TOLA_RS08240 fb547f7edd8f76d9b631bbfc8f00f84e 188 SUPERFAMILY SSF69737 76 142 7.46E-20 T 22-04-2016 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 TOLA_RS12845 86ac1bf8657be716354157c243377334 368 PIRSF PIRSF001259 1 368 4.9E-123 T 22-04-2016 TOLA_RS12845 86ac1bf8657be716354157c243377334 368 PANTHER PTHR21327 1 366 2.3E-150 T 22-04-2016 TOLA_RS12845 86ac1bf8657be716354157c243377334 368 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 3 199 3.0E-75 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS12845 86ac1bf8657be716354157c243377334 368 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 9.5E-84 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS12845 86ac1bf8657be716354157c243377334 368 SUPERFAMILY SSF55821 2 203 2.52E-86 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TOLA_RS12845 86ac1bf8657be716354157c243377334 368 Pfam PF00925 GTP cyclohydrolase II 209 366 7.5E-36 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 TOLA_RS12845 86ac1bf8657be716354157c243377334 368 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 39.096 T 22-04-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS12845 86ac1bf8657be716354157c243377334 368 Gene3D G3DSA:3.90.870.10 1 209 5.5E-99 T 22-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TOLA_RS12845 86ac1bf8657be716354157c243377334 368 PANTHER PTHR21327:SF6 1 366 2.3E-150 T 22-04-2016 TOLA_RS12845 86ac1bf8657be716354157c243377334 368 SUPERFAMILY SSF142695 205 366 4.71E-43 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 TOLA_RS13980 d726fcd305f8e97a549c092d131aa448 378 PANTHER PTHR21666:SF222 259 376 7.4E-53 T 22-04-2016 TOLA_RS13980 d726fcd305f8e97a549c092d131aa448 378 Pfam PF01551 Peptidase family M23 277 371 2.6E-29 T 22-04-2016 IPR016047 Peptidase M23 TOLA_RS13980 d726fcd305f8e97a549c092d131aa448 378 Gene3D G3DSA:3.10.350.10 88 131 5.2E-11 T 22-04-2016 IPR018392 LysM domain TOLA_RS13980 d726fcd305f8e97a549c092d131aa448 378 Gene3D G3DSA:3.10.350.10 152 194 2.3E-8 T 22-04-2016 IPR018392 LysM domain TOLA_RS13980 d726fcd305f8e97a549c092d131aa448 378 Gene3D G3DSA:2.70.70.10 238 376 2.9E-39 T 22-04-2016 TOLA_RS13980 d726fcd305f8e97a549c092d131aa448 378 PANTHER PTHR21666 259 376 7.4E-53 T 22-04-2016 TOLA_RS13980 d726fcd305f8e97a549c092d131aa448 378 SUPERFAMILY SSF51261 155 375 4.5E-48 T 22-04-2016 IPR011055 Duplicated hybrid motif TOLA_RS13980 d726fcd305f8e97a549c092d131aa448 378 Pfam PF01476 LysM domain 153 196 2.3E-6 T 22-04-2016 IPR018392 LysM domain TOLA_RS13980 d726fcd305f8e97a549c092d131aa448 378 Pfam PF01476 LysM domain 90 131 1.5E-8 T 22-04-2016 IPR018392 LysM domain TOLA_RS13980 d726fcd305f8e97a549c092d131aa448 378 SMART SM00257 89 133 1.4E-9 T 22-04-2016 IPR018392 LysM domain TOLA_RS13980 d726fcd305f8e97a549c092d131aa448 378 SMART SM00257 152 196 1.7E-6 T 22-04-2016 IPR018392 LysM domain TOLA_RS13980 d726fcd305f8e97a549c092d131aa448 378 SUPERFAMILY SSF54106 89 131 1.28E-7 T 22-04-2016 IPR018392 LysM domain TOLA_RS13085 c70c0997f1c1ff48765e6aa2cf7f1100 290 PIRSF PIRSF000103 2 290 4.2E-74 T 22-04-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 TOLA_RS13085 c70c0997f1c1ff48765e6aa2cf7f1100 290 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 168 286 1.3E-31 T 22-04-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 TOLA_RS13085 c70c0997f1c1ff48765e6aa2cf7f1100 290 PANTHER PTHR22981:SF49 2 290 1.3E-139 T 22-04-2016 TOLA_RS13085 c70c0997f1c1ff48765e6aa2cf7f1100 290 SUPERFAMILY SSF48179 167 289 4.53E-38 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS13085 c70c0997f1c1ff48765e6aa2cf7f1100 290 PANTHER PTHR22981 2 290 1.3E-139 T 22-04-2016 TOLA_RS13085 c70c0997f1c1ff48765e6aa2cf7f1100 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 165 5.1E-48 T 22-04-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 TOLA_RS13085 c70c0997f1c1ff48765e6aa2cf7f1100 290 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 8 21 - T 22-04-2016 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 TOLA_RS13085 c70c0997f1c1ff48765e6aa2cf7f1100 290 SUPERFAMILY SSF51735 5 167 1.91E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS13085 c70c0997f1c1ff48765e6aa2cf7f1100 290 Gene3D G3DSA:3.40.50.720 4 165 2.1E-52 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS13085 c70c0997f1c1ff48765e6aa2cf7f1100 290 Gene3D G3DSA:1.10.1040.10 168 289 6.2E-40 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TOLA_RS04160 cca9712ad7fffacf417635d8bf68d397 176 PANTHER PTHR22573:SF56 1 175 9.5E-76 T 22-04-2016 TOLA_RS04160 cca9712ad7fffacf417635d8bf68d397 176 Gene3D G3DSA:3.40.50.2020 2 174 2.0E-74 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS04160 cca9712ad7fffacf417635d8bf68d397 176 PANTHER PTHR22573 1 175 9.5E-76 T 22-04-2016 TOLA_RS04160 cca9712ad7fffacf417635d8bf68d397 176 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 7 172 1.3E-68 T 22-04-2016 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620|UniPathway: UPA00591 TOLA_RS04160 cca9712ad7fffacf417635d8bf68d397 176 SUPERFAMILY SSF53271 2 175 2.49E-51 T 22-04-2016 IPR029057 Phosphoribosyltransferase-like TOLA_RS04160 cca9712ad7fffacf417635d8bf68d397 176 Pfam PF00156 Phosphoribosyl transferase domain 15 159 6.8E-23 T 22-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 TOLA_RS10535 6e60081cc21ce28d5585476cff9ab757 454 Pfam PF16325 Peptidase family U32 C-terminal domain 358 439 6.5E-22 T 22-04-2016 IPR032525 Peptidase family U32, C-terminal KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS10535 6e60081cc21ce28d5585476cff9ab757 454 PANTHER PTHR30217:SF6 245 452 1.3E-233 T 22-04-2016 TOLA_RS10535 6e60081cc21ce28d5585476cff9ab757 454 PANTHER PTHR30217:SF6 1 206 1.3E-233 T 22-04-2016 TOLA_RS10535 6e60081cc21ce28d5585476cff9ab757 454 PANTHER PTHR30217 245 452 1.3E-233 T 22-04-2016 TOLA_RS10535 6e60081cc21ce28d5585476cff9ab757 454 PANTHER PTHR30217 1 206 1.3E-233 T 22-04-2016 TOLA_RS10535 6e60081cc21ce28d5585476cff9ab757 454 Pfam PF01136 Peptidase family U32 75 341 5.7E-97 T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS10535 6e60081cc21ce28d5585476cff9ab757 454 ProSitePatterns PS01276 Peptidase family U32 signature. 162 180 - T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS10670 50b8735e648413e69c62097945ec88fe 393 SUPERFAMILY SSF53756 18 389 2.55E-32 T 22-04-2016 TOLA_RS10670 50b8735e648413e69c62097945ec88fe 393 Gene3D G3DSA:3.40.50.2000 171 301 1.4E-6 T 22-04-2016 TOLA_RS10670 50b8735e648413e69c62097945ec88fe 393 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 16 390 41.899 T 22-04-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 TOLA_RS10670 50b8735e648413e69c62097945ec88fe 393 PANTHER PTHR30372 2 393 1.2E-134 T 22-04-2016 TOLA_RS10670 50b8735e648413e69c62097945ec88fe 393 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 14 387 7.4E-146 T 22-04-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 TOLA_RS10670 50b8735e648413e69c62097945ec88fe 393 PANTHER PTHR30372:SF0 2 393 1.2E-134 T 22-04-2016 TOLA_RS10670 50b8735e648413e69c62097945ec88fe 393 Pfam PF02684 Lipid-A-disaccharide synthetase 19 385 3.7E-131 T 22-04-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 TOLA_RS11450 28c788bd0f6b0b273c7046724c4af4a2 97 SUPERFAMILY SSF75471 1 95 9.55E-31 T 22-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 TOLA_RS11450 28c788bd0f6b0b273c7046724c4af4a2 97 Gene3D G3DSA:3.30.110.60 1 94 1.9E-32 T 22-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 TOLA_RS11450 28c788bd0f6b0b273c7046724c4af4a2 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 3 96 9.8E-37 T 22-04-2016 IPR017924 RNA-binding protein YhbY GO:0003723 TOLA_RS11450 28c788bd0f6b0b273c7046724c4af4a2 97 PANTHER PTHR31846 1 97 3.6E-37 T 22-04-2016 TOLA_RS11450 28c788bd0f6b0b273c7046724c4af4a2 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 97 1.0E-32 T 22-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 TOLA_RS11450 28c788bd0f6b0b273c7046724c4af4a2 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 1.2E-20 T 22-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 TOLA_RS11450 28c788bd0f6b0b273c7046724c4af4a2 97 SMART SM01103 3 86 7.2E-39 T 22-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 TOLA_RS11850 148d881ff85b4ab185a2b2125ca4f649 183 Pfam PF14697 4Fe-4S dicluster domain 103 155 2.1E-11 T 22-04-2016 TOLA_RS11850 148d881ff85b4ab185a2b2125ca4f649 183 SUPERFAMILY SSF54862 37 160 1.62E-23 T 22-04-2016 TOLA_RS11850 148d881ff85b4ab185a2b2125ca4f649 183 PANTHER PTHR11938 7 160 2.1E-32 T 22-04-2016 TOLA_RS11850 148d881ff85b4ab185a2b2125ca4f649 183 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 140 151 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS11850 148d881ff85b4ab185a2b2125ca4f649 183 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 8 163 9.9E-53 T 22-04-2016 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 TOLA_RS11850 148d881ff85b4ab185a2b2125ca4f649 183 Gene3D G3DSA:3.30.70.20 47 115 9.2E-5 T 22-04-2016 TOLA_RS11850 148d881ff85b4ab185a2b2125ca4f649 183 Pfam PF04060 Putative Fe-S cluster 43 75 1.3E-8 T 22-04-2016 IPR007202 4Fe-4S domain GO:0051536 TOLA_RS11850 148d881ff85b4ab185a2b2125ca4f649 183 Gene3D G3DSA:3.30.70.20 116 161 1.6E-13 T 22-04-2016 TOLA_RS11850 148d881ff85b4ab185a2b2125ca4f649 183 PANTHER PTHR11938:SF64 7 160 2.1E-32 T 22-04-2016 TOLA_RS11850 148d881ff85b4ab185a2b2125ca4f649 183 Hamap MF_00463 Electron transport complex subunit RsxB [rsxB]. 3 182 33.01 T 22-04-2016 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 TOLA_RS08670 75fe4131d2bdf7912eaa8caf9aa9c024 359 PANTHER PTHR11751:SF338 1 350 1.3E-88 T 22-04-2016 TOLA_RS08670 75fe4131d2bdf7912eaa8caf9aa9c024 359 Pfam PF00155 Aminotransferase class I and II 24 350 3.8E-45 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TOLA_RS08670 75fe4131d2bdf7912eaa8caf9aa9c024 359 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 7 352 3.1E-104 T 22-04-2016 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443|UniPathway: UPA00148 TOLA_RS08670 75fe4131d2bdf7912eaa8caf9aa9c024 359 SUPERFAMILY SSF53383 6 355 1.48E-81 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS08670 75fe4131d2bdf7912eaa8caf9aa9c024 359 Gene3D G3DSA:3.90.1150.10 256 356 3.5E-31 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS08670 75fe4131d2bdf7912eaa8caf9aa9c024 359 Gene3D G3DSA:3.40.640.10 38 255 1.7E-64 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS08670 75fe4131d2bdf7912eaa8caf9aa9c024 359 PANTHER PTHR11751 1 350 1.3E-88 T 22-04-2016 TOLA_RS08670 75fe4131d2bdf7912eaa8caf9aa9c024 359 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 212 225 - T 22-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 TOLA_RS00600 146e79e6151036eac6c0c85d37c4ad36 117 Gene3D G3DSA:3.30.420.100 24 117 4.1E-34 T 22-04-2016 TOLA_RS00600 146e79e6151036eac6c0c85d37c4ad36 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 117 6.1E-42 T 22-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00600 146e79e6151036eac6c0c85d37c4ad36 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 24.7 T 22-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00600 146e79e6151036eac6c0c85d37c4ad36 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 117 1.0E-40 T 22-04-2016 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00600 146e79e6151036eac6c0c85d37c4ad36 117 PANTHER PTHR12899 1 117 7.6E-42 T 22-04-2016 TOLA_RS00600 146e79e6151036eac6c0c85d37c4ad36 117 SUPERFAMILY SSF53137 3 115 2.14E-48 T 22-04-2016 TOLA_RS03900 84e015d826fe4b3bc20a66d33ebd2234 292 Gene3D G3DSA:3.30.479.10 152 289 4.0E-21 T 22-04-2016 TOLA_RS03900 84e015d826fe4b3bc20a66d33ebd2234 292 Gene3D G3DSA:3.30.479.10 15 140 4.3E-19 T 22-04-2016 TOLA_RS03900 84e015d826fe4b3bc20a66d33ebd2234 292 SUPERFAMILY SSF55620 1 154 7.78E-28 T 22-04-2016 TOLA_RS03900 84e015d826fe4b3bc20a66d33ebd2234 292 SUPERFAMILY SSF55620 151 289 3.39E-27 T 22-04-2016 TOLA_RS03900 84e015d826fe4b3bc20a66d33ebd2234 292 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 150 279 1.2E-7 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein TOLA_RS03900 84e015d826fe4b3bc20a66d33ebd2234 292 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 24 138 1.5E-7 T 22-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein TOLA_RS14360 566c8cf48eaedfa5f4266b1ee284c76a 479 PANTHER PTHR36846 1 479 3.3E-79 T 22-04-2016 TOLA_RS14360 566c8cf48eaedfa5f4266b1ee284c76a 479 SUPERFAMILY SSF53300 314 463 3.89E-18 T 22-04-2016 IPR002035 von Willebrand factor, type A TOLA_RS14360 566c8cf48eaedfa5f4266b1ee284c76a 479 SMART SM00327 317 479 0.0041 T 22-04-2016 IPR002035 von Willebrand factor, type A TOLA_RS14360 566c8cf48eaedfa5f4266b1ee284c76a 479 Pfam PF05762 VWA domain containing CoxE-like protein 314 444 3.0E-7 T 22-04-2016 IPR008912 Uncharacterised protein family CoxE-like TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 84 298 2.2E-78 T 22-04-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 PANTHER PTHR31637:SF0 1 512 2.1E-280 T 22-04-2016 TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 Gene3D G3DSA:3.40.1450.10 80 310 1.2E-92 T 22-04-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 SUPERFAMILY SSF53649 5 79 1.13E-74 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 SUPERFAMILY SSF53649 310 508 1.13E-74 T 22-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 PANTHER PTHR31637 1 512 2.1E-280 T 22-04-2016 TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 6 509 6.5E-225 T 22-04-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 6 510 48.916 T 22-04-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 SUPERFAMILY SSF64158 79 309 1.57E-81 T 22-04-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 Pfam PF01676 Metalloenzyme superfamily 6 498 9.4E-79 T 22-04-2016 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 Gene3D G3DSA:3.40.720.10 314 509 3.7E-90 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 Gene3D G3DSA:3.40.720.10 5 79 3.7E-90 T 22-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 TOLA_RS02620 cf3d9eefebcec14cf0e6742f2b6b92da 512 PIRSF PIRSF001492 1 512 2.1E-202 T 22-04-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 TOLA_RS14830 5bfb419033ea3062d14774ad0f26d228 451 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 13 447 2.6E-134 T 22-04-2016 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 TOLA_RS14830 5bfb419033ea3062d14774ad0f26d228 451 PANTHER PTHR11328:SF35 2 448 3.4E-166 T 22-04-2016 TOLA_RS14830 5bfb419033ea3062d14774ad0f26d228 451 PANTHER PTHR11328 2 448 3.4E-166 T 22-04-2016 TOLA_RS14830 5bfb419033ea3062d14774ad0f26d228 451 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 63 88 - T 22-04-2016 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 TOLA_RS14830 5bfb419033ea3062d14774ad0f26d228 451 Gene3D G3DSA:1.20.1250.20 230 439 4.0E-17 T 22-04-2016 TOLA_RS14830 5bfb419033ea3062d14774ad0f26d228 451 Gene3D G3DSA:1.20.1250.20 10 215 1.2E-12 T 22-04-2016 TOLA_RS14830 5bfb419033ea3062d14774ad0f26d228 451 SUPERFAMILY SSF103473 1 436 2.35E-38 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS14830 5bfb419033ea3062d14774ad0f26d228 451 Pfam PF13347 MFS/sugar transport protein 14 434 7.4E-96 T 22-04-2016 TOLA_RS11760 80309a063d10e2cf86d9954baea8ebb0 870 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 14 184 4.2E-40 T 22-04-2016 IPR025199 DNA translocase FtsK, 4TM region TOLA_RS11760 80309a063d10e2cf86d9954baea8ebb0 870 Gene3D G3DSA:3.40.50.300 459 765 7.5E-96 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11760 80309a063d10e2cf86d9954baea8ebb0 870 PANTHER PTHR22683:SF41 325 865 1.7E-295 T 22-04-2016 TOLA_RS11760 80309a063d10e2cf86d9954baea8ebb0 870 SUPERFAMILY SSF46785 802 865 1.5E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11760 80309a063d10e2cf86d9954baea8ebb0 870 SUPERFAMILY SSF52540 458 771 5.31E-51 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11760 80309a063d10e2cf86d9954baea8ebb0 870 SMART SM00843 802 867 1.2E-40 T 22-04-2016 IPR018541 FtsK gamma domain TOLA_RS11760 80309a063d10e2cf86d9954baea8ebb0 870 Pfam PF01580 FtsK/SpoIIIE family 485 698 1.1E-70 T 22-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TOLA_RS11760 80309a063d10e2cf86d9954baea8ebb0 870 PANTHER PTHR22683 325 865 1.7E-295 T 22-04-2016 TOLA_RS11760 80309a063d10e2cf86d9954baea8ebb0 870 Pfam PF09397 Ftsk gamma domain 804 864 7.9E-28 T 22-04-2016 IPR018541 FtsK gamma domain TOLA_RS02225 b9eef63aa055b4592f2d415365d7375e 124 SUPERFAMILY SSF52980 14 119 1.53E-18 T 22-04-2016 IPR011335 Restriction endonuclease type II-like TOLA_RS02225 b9eef63aa055b4592f2d415365d7375e 124 Pfam PF02021 Uncharacterised protein family UPF0102 20 111 3.1E-25 T 22-04-2016 IPR003509 Uncharacterised protein family UPF0102 TOLA_RS02225 b9eef63aa055b4592f2d415365d7375e 124 PANTHER PTHR34039 9 124 1.2E-33 T 22-04-2016 TOLA_RS02225 b9eef63aa055b4592f2d415365d7375e 124 PANTHER PTHR34039:SF1 9 124 1.2E-33 T 22-04-2016 TOLA_RS02225 b9eef63aa055b4592f2d415365d7375e 124 Gene3D G3DSA:3.40.1350.10 20 124 1.4E-33 T 22-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 TOLA_RS02225 b9eef63aa055b4592f2d415365d7375e 124 Hamap MF_00048 UPF0102 protein YraN [yraN]. 13 124 19.85 T 22-04-2016 IPR003509 Uncharacterised protein family UPF0102 TOLA_RS02225 b9eef63aa055b4592f2d415365d7375e 124 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 10 123 8.0E-34 T 22-04-2016 IPR003509 Uncharacterised protein family UPF0102 TOLA_RS16065 fd86cab4c77696e408e897fb8c292bac 406 Pfam PF00909 Ammonium Transporter Family 20 398 1.7E-89 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 TOLA_RS16065 fd86cab4c77696e408e897fb8c292bac 406 PANTHER PTHR11730:SF6 4 403 2.9E-115 T 22-04-2016 TOLA_RS16065 fd86cab4c77696e408e897fb8c292bac 406 SUPERFAMILY SSF111352 14 381 1.18E-93 T 22-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 TOLA_RS16065 fd86cab4c77696e408e897fb8c292bac 406 Gene3D G3DSA:1.10.3430.10 13 381 8.3E-91 T 22-04-2016 IPR029020 Ammonium/urea transporter TOLA_RS16065 fd86cab4c77696e408e897fb8c292bac 406 PANTHER PTHR11730 4 403 2.9E-115 T 22-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 TOLA_RS13800 75e3932f8838021ff31719fcd172dd68 349 Gene3D G3DSA:3.30.1150.10 268 345 4.6E-22 T 22-04-2016 TOLA_RS13800 75e3932f8838021ff31719fcd172dd68 349 TIGRFAM TIGR02794 tolA_full: protein TolA 4 347 3.0E-65 T 22-04-2016 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 TOLA_RS13800 75e3932f8838021ff31719fcd172dd68 349 SUPERFAMILY SSF74653 267 341 2.35E-16 T 22-04-2016 TOLA_RS13800 75e3932f8838021ff31719fcd172dd68 349 Pfam PF06519 TolA C-terminal 269 338 4.6E-19 T 22-04-2016 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 TOLA_RS15140 de00c071ec1c8c1539afb4e0d3f15e0e 310 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 286 39.659 T 22-04-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 TOLA_RS15140 de00c071ec1c8c1539afb4e0d3f15e0e 310 Pfam PF02401 LytB protein 3 282 7.8E-97 T 22-04-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 TOLA_RS15140 de00c071ec1c8c1539afb4e0d3f15e0e 310 PANTHER PTHR30426 1 310 6.3E-161 T 22-04-2016 TOLA_RS15140 de00c071ec1c8c1539afb4e0d3f15e0e 310 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 284 1.1E-105 T 22-04-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 TOLA_RS12000 ea66298fa3a31ea1af63d627e9fcce1c 675 SMART SM00331 443 666 1.0E-4 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TOLA_RS12000 ea66298fa3a31ea1af63d627e9fcce1c 675 Gene3D G3DSA:3.30.450.20 173 311 6.1E-9 T 22-04-2016 TOLA_RS12000 ea66298fa3a31ea1af63d627e9fcce1c 675 Pfam PF00672 HAMP domain 318 386 9.5E-11 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS12000 ea66298fa3a31ea1af63d627e9fcce1c 675 SUPERFAMILY SSF158472 339 387 1.09E-7 T 22-04-2016 TOLA_RS12000 ea66298fa3a31ea1af63d627e9fcce1c 675 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 467 662 9.8E-19 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TOLA_RS12000 ea66298fa3a31ea1af63d627e9fcce1c 675 SMART SM00304 338 390 2.1E-7 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS12000 ea66298fa3a31ea1af63d627e9fcce1c 675 PANTHER PTHR32089 3 666 3.5E-75 T 22-04-2016 TOLA_RS12000 ea66298fa3a31ea1af63d627e9fcce1c 675 SUPERFAMILY SSF81606 453 661 3.92E-5 T 22-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TOLA_RS12000 ea66298fa3a31ea1af63d627e9fcce1c 675 PANTHER PTHR32089:SF27 3 666 3.5E-75 T 22-04-2016 TOLA_RS07305 13e65bf9d7cbfd228b02dfcf0c5d2e9c 232 Gene3D G3DSA:3.40.50.150 18 215 1.2E-43 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07305 13e65bf9d7cbfd228b02dfcf0c5d2e9c 232 Pfam PF13489 Methyltransferase domain 48 197 1.2E-24 T 22-04-2016 TOLA_RS07305 13e65bf9d7cbfd228b02dfcf0c5d2e9c 232 SUPERFAMILY SSF53335 11 227 9.71E-46 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07305 13e65bf9d7cbfd228b02dfcf0c5d2e9c 232 PANTHER PTHR10108 2 226 1.0E-120 T 22-04-2016 TOLA_RS07305 13e65bf9d7cbfd228b02dfcf0c5d2e9c 232 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 5 231 38.979 T 22-04-2016 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|UniPathway: UPA00232 TOLA_RS07305 13e65bf9d7cbfd228b02dfcf0c5d2e9c 232 PANTHER PTHR10108:SF910 2 226 1.0E-120 T 22-04-2016 TOLA_RS07305 13e65bf9d7cbfd228b02dfcf0c5d2e9c 232 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 7 224 1.4E-88 T 22-04-2016 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|UniPathway: UPA00232 TOLA_RS06545 302e39778d0204ac1d2b2a01771e0c46 256 PIRSF PIRSF018455 1 256 6.3E-93 T 22-04-2016 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 TOLA_RS06545 302e39778d0204ac1d2b2a01771e0c46 256 Pfam PF03411 Penicillin-insensitive murein endopeptidase 18 251 2.8E-90 T 22-04-2016 IPR005073 Peptidase M74, penicillin-insensitive murein endopeptidase GO:0004252|GO:0006508|GO:0030288 TOLA_RS06545 302e39778d0204ac1d2b2a01771e0c46 256 SUPERFAMILY SSF55166 4 254 2.59E-85 T 22-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain TOLA_RS06545 302e39778d0204ac1d2b2a01771e0c46 256 Gene3D G3DSA:3.30.1380.10 3 254 1.3E-90 T 22-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain TOLA_RS02490 cea611d88cdf1de6d37bc14673e007da 723 TIGRFAM TIGR00595 priA: primosomal protein N' 212 719 8.8E-191 T 22-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 TOLA_RS02490 cea611d88cdf1de6d37bc14673e007da 723 Gene3D G3DSA:3.40.50.300 191 373 2.4E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02490 cea611d88cdf1de6d37bc14673e007da 723 Pfam PF00270 DEAD/DEAH box helicase 198 354 5.8E-14 T 22-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TOLA_RS02490 cea611d88cdf1de6d37bc14673e007da 723 Hamap MF_00983 Probable primosomal protein N' [priA]. 1 721 23.857 T 22-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 TOLA_RS02490 cea611d88cdf1de6d37bc14673e007da 723 SMART SM00487 187 386 2.4E-17 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS02490 cea611d88cdf1de6d37bc14673e007da 723 Pfam PF00271 Helicase conserved C-terminal domain 487 579 2.7E-6 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS02490 cea611d88cdf1de6d37bc14673e007da 723 SUPERFAMILY SSF52540 187 364 4.27E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02490 cea611d88cdf1de6d37bc14673e007da 723 SUPERFAMILY SSF52540 451 601 6.03E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02490 cea611d88cdf1de6d37bc14673e007da 723 Gene3D G3DSA:3.40.50.300 448 624 1.4E-30 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02490 cea611d88cdf1de6d37bc14673e007da 723 SMART SM00490 483 580 5.4E-12 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS02490 cea611d88cdf1de6d37bc14673e007da 723 PANTHER PTHR30580 1 722 1.8E-256 T 22-04-2016 TOLA_RS07500 faeffe57f759b879dd2bb23096941b17 506 SUPERFAMILY SSF52540 7 220 1.03E-59 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07500 faeffe57f759b879dd2bb23096941b17 506 PANTHER PTHR24220:SF239 9 384 8.1E-159 T 22-04-2016 TOLA_RS07500 faeffe57f759b879dd2bb23096941b17 506 SMART SM00382 32 226 3.2E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS07500 faeffe57f759b879dd2bb23096941b17 506 Gene3D G3DSA:3.40.50.300 7 222 1.8E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07500 faeffe57f759b879dd2bb23096941b17 506 Gene3D G3DSA:3.40.50.300 254 497 7.6E-38 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07500 faeffe57f759b879dd2bb23096941b17 506 PANTHER PTHR24220 9 384 8.1E-159 T 22-04-2016 TOLA_RS07500 faeffe57f759b879dd2bb23096941b17 506 SUPERFAMILY SSF52540 257 489 2.44E-35 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07500 faeffe57f759b879dd2bb23096941b17 506 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS07500 faeffe57f759b879dd2bb23096941b17 506 Pfam PF00005 ABC transporter 274 429 3.8E-10 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS07500 faeffe57f759b879dd2bb23096941b17 506 Pfam PF00005 ABC transporter 24 170 3.8E-35 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS07935 dbb5dffef6013dd8f58003b9a161bead 93 Pfam PF00216 Bacterial DNA-binding protein 1 91 8.6E-31 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS07935 dbb5dffef6013dd8f58003b9a161bead 93 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 92 8.0E-44 T 22-04-2016 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 TOLA_RS07935 dbb5dffef6013dd8f58003b9a161bead 93 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 22-04-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 TOLA_RS07935 dbb5dffef6013dd8f58003b9a161bead 93 SUPERFAMILY SSF47729 1 91 8.83E-30 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 TOLA_RS07935 dbb5dffef6013dd8f58003b9a161bead 93 PANTHER PTHR33175:SF5 1 93 1.8E-47 T 22-04-2016 TOLA_RS07935 dbb5dffef6013dd8f58003b9a161bead 93 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 92 28.893 T 22-04-2016 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 TOLA_RS07935 dbb5dffef6013dd8f58003b9a161bead 93 SMART SM00411 1 91 7.1E-42 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS07935 dbb5dffef6013dd8f58003b9a161bead 93 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 9.7E-19 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS07935 dbb5dffef6013dd8f58003b9a161bead 93 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 9.7E-19 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS07935 dbb5dffef6013dd8f58003b9a161bead 93 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 9.7E-19 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS07935 dbb5dffef6013dd8f58003b9a161bead 93 Gene3D G3DSA:4.10.520.10 1 92 1.8E-34 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 TOLA_RS07935 dbb5dffef6013dd8f58003b9a161bead 93 PANTHER PTHR33175 1 93 1.8E-47 T 22-04-2016 TOLA_RS09320 07fdcef4bfbc6422ad1db4876e41c784 202 Pfam PF10054 Predicted periplasmic lipoprotein (DUF2291) 14 199 1.1E-35 T 22-04-2016 IPR014582 Uncharacterised conserved protein UCP033535, periplasmic lipoprotein TOLA_RS09320 07fdcef4bfbc6422ad1db4876e41c784 202 SUPERFAMILY SSF141318 49 199 8.24E-35 T 22-04-2016 TOLA_RS09320 07fdcef4bfbc6422ad1db4876e41c784 202 PIRSF PIRSF033535 2 202 5.9E-37 T 22-04-2016 IPR014582 Uncharacterised conserved protein UCP033535, periplasmic lipoprotein TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 PANTHER PTHR19375:SF182 301 420 9.3E-83 T 22-04-2016 TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 PANTHER PTHR19375:SF182 65 248 9.3E-83 T 22-04-2016 TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 PANTHER PTHR19375:SF182 1 44 9.3E-83 T 22-04-2016 TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 22-04-2016 IPR018181 Heat shock protein 70, conserved site TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 Gene3D G3DSA:3.30.420.40 198 220 3.0E-11 T 22-04-2016 TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 Gene3D G3DSA:3.30.420.40 353 402 3.0E-11 T 22-04-2016 TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 SUPERFAMILY SSF53067 2 184 1.19E-23 T 22-04-2016 TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 PANTHER PTHR19375 301 420 9.3E-83 T 22-04-2016 TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 PANTHER PTHR19375 65 248 9.3E-83 T 22-04-2016 TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 PANTHER PTHR19375 1 44 9.3E-83 T 22-04-2016 TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 Gene3D G3DSA:3.30.420.40 3 197 9.6E-28 T 22-04-2016 TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 Pfam PF00012 Hsp70 protein 3 209 2.9E-13 T 22-04-2016 IPR013126 Heat shock protein 70 family TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 SUPERFAMILY SSF53067 307 426 4.68E-28 T 22-04-2016 TOLA_RS09175 1bf67dd0b9b7db9783ab71ec019d7e72 429 SUPERFAMILY SSF53067 189 255 4.68E-28 T 22-04-2016 TOLA_RS15370 672f20c2e3f54742215f73989064049a 411 PANTHER PTHR30578:SF1 3 411 1.9E-245 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 TOLA_RS15370 672f20c2e3f54742215f73989064049a 411 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 3 407 6.8E-191 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 TOLA_RS15370 672f20c2e3f54742215f73989064049a 411 Pfam PF03116 NQR2, RnfD, RnfE family 42 404 5.8E-105 T 22-04-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 TOLA_RS15370 672f20c2e3f54742215f73989064049a 411 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 2 411 36.034 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 TOLA_RS15370 672f20c2e3f54742215f73989064049a 411 PANTHER PTHR30578 3 411 1.9E-245 T 22-04-2016 TOLA_RS15370 672f20c2e3f54742215f73989064049a 411 PIRSF PIRSF016055 1 411 4.1E-193 T 22-04-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 SUPERFAMILY SSF47240 1 154 2.03E-41 T 22-04-2016 IPR009078 Ferritin-like superfamily TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 PANTHER PTHR30295:SF9 1 154 3.1E-40 T 22-04-2016 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 PANTHER PTHR30295 1 154 3.1E-40 T 22-04-2016 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 PRINTS PR00601 Bacterioferritin signature 65 85 5.5E-55 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 PRINTS PR00601 Bacterioferritin signature 107 127 5.5E-55 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 PRINTS PR00601 Bacterioferritin signature 23 43 5.5E-55 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 PRINTS PR00601 Bacterioferritin signature 3 22 5.5E-55 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 PRINTS PR00601 Bacterioferritin signature 128 149 5.5E-55 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 PRINTS PR00601 Bacterioferritin signature 86 106 5.5E-55 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 PRINTS PR00601 Bacterioferritin signature 44 64 5.5E-55 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 Gene3D G3DSA:1.20.1260.10 1 154 1.4E-50 T 22-04-2016 IPR012347 Ferritin-related TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 PIRSF PIRSF002560 1 154 2.1E-60 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 TIGRFAM TIGR00754 bfr: bacterioferritin 1 154 1.3E-62 T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 Pfam PF00210 Ferritin-like domain 8 142 6.0E-31 T 22-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TOLA_RS15960 cd4e18472164bd5ba6a6d7fe9edded0e 154 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 22-04-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TOLA_RS00345 b2f7317904e72accb8c0d00caed1a645 140 Pfam PF12802 MarR family 36 93 9.8E-9 T 22-04-2016 TOLA_RS00345 b2f7317904e72accb8c0d00caed1a645 140 SMART SM00347 30 130 6.7E-12 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS00345 b2f7317904e72accb8c0d00caed1a645 140 Gene3D G3DSA:1.10.10.10 6 140 3.0E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00345 b2f7317904e72accb8c0d00caed1a645 140 SUPERFAMILY SSF46785 11 136 2.6E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07125 d0cc60b2e8d33a399c89d8097660187c 289 SUPERFAMILY SSF56112 29 269 4.08E-22 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS07125 d0cc60b2e8d33a399c89d8097660187c 289 PIRSF PIRSF006221 1 287 6.3E-46 T 22-04-2016 IPR016477 Fructosamine/Ketosamine-3-kinase TOLA_RS07125 d0cc60b2e8d33a399c89d8097660187c 289 PANTHER PTHR12149 107 266 7.7E-32 T 22-04-2016 TOLA_RS07125 d0cc60b2e8d33a399c89d8097660187c 289 Gene3D G3DSA:3.90.1200.10 105 252 1.6E-9 T 22-04-2016 TOLA_RS07125 d0cc60b2e8d33a399c89d8097660187c 289 Pfam PF03881 Fructosamine kinase 1 270 2.9E-60 T 22-04-2016 IPR016477 Fructosamine/Ketosamine-3-kinase TOLA_RS07125 d0cc60b2e8d33a399c89d8097660187c 289 PANTHER PTHR12149:SF8 107 266 7.7E-32 T 22-04-2016 TOLA_RS11695 d4ccc99dd7d8f83467e3135cace944be 197 PANTHER PTHR17224 7 195 1.3E-83 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TOLA_RS11695 d4ccc99dd7d8f83467e3135cace944be 197 SUPERFAMILY SSF53178 5 194 2.49E-71 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TOLA_RS11695 d4ccc99dd7d8f83467e3135cace944be 197 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 6 192 6.2E-68 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TOLA_RS11695 d4ccc99dd7d8f83467e3135cace944be 197 Gene3D G3DSA:3.40.50.1470 2 193 1.9E-73 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TOLA_RS11695 d4ccc99dd7d8f83467e3135cace944be 197 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 112 122 - T 22-04-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 TOLA_RS11695 d4ccc99dd7d8f83467e3135cace944be 197 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 5 184 35.833 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TOLA_RS11695 d4ccc99dd7d8f83467e3135cace944be 197 Pfam PF01195 Peptidyl-tRNA hydrolase 7 189 1.5E-55 T 22-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TOLA_RS04430 a2fd0c2cf1c7e8b6c068734940705608 261 SMART SM00382 40 229 6.6E-19 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS04430 a2fd0c2cf1c7e8b6c068734940705608 261 PANTHER PTHR24220 8 255 1.7E-109 T 22-04-2016 TOLA_RS04430 a2fd0c2cf1c7e8b6c068734940705608 261 Gene3D G3DSA:3.40.50.300 2 253 2.3E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04430 a2fd0c2cf1c7e8b6c068734940705608 261 Pfam PF00005 ABC transporter 31 179 2.1E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS04430 a2fd0c2cf1c7e8b6c068734940705608 261 PANTHER PTHR24220:SF81 8 255 1.7E-109 T 22-04-2016 TOLA_RS04430 a2fd0c2cf1c7e8b6c068734940705608 261 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS04430 a2fd0c2cf1c7e8b6c068734940705608 261 SUPERFAMILY SSF52540 5 255 3.15E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08470 e2dd83acf3bafda851cf167721f9ae0f 518 Gene3D G3DSA:3.40.50.880 257 466 3.4E-30 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS08470 e2dd83acf3bafda851cf167721f9ae0f 518 SUPERFAMILY SSF52317 257 451 9.17E-35 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS08470 e2dd83acf3bafda851cf167721f9ae0f 518 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 503 2.3E-163 T 22-04-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 TOLA_RS08470 e2dd83acf3bafda851cf167721f9ae0f 518 Gene3D G3DSA:3.40.50.300 4 239 1.2E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08470 e2dd83acf3bafda851cf167721f9ae0f 518 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 511 182.147 T 22-04-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 TOLA_RS08470 e2dd83acf3bafda851cf167721f9ae0f 518 SUPERFAMILY SSF52540 1 228 5.0E-54 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08470 e2dd83acf3bafda851cf167721f9ae0f 518 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 258 455 3.6E-55 T 22-04-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 TOLA_RS08470 e2dd83acf3bafda851cf167721f9ae0f 518 PANTHER PTHR21343 1 508 5.8E-218 T 22-04-2016 TOLA_RS08470 e2dd83acf3bafda851cf167721f9ae0f 518 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 228 9.8E-30 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TOLA_RS08470 e2dd83acf3bafda851cf167721f9ae0f 518 PANTHER PTHR21343:SF1 1 508 5.8E-218 T 22-04-2016 TOLA_RS11340 a13d247baf612f244994509d557922a4 326 PANTHER PTHR30160 1 322 3.9E-93 T 22-04-2016 TOLA_RS11340 a13d247baf612f244994509d557922a4 326 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 13 317 1.3E-116 T 22-04-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 TOLA_RS11340 a13d247baf612f244994509d557922a4 326 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 19 313 1.6E-87 T 22-04-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 TOLA_RS11340 a13d247baf612f244994509d557922a4 326 SUPERFAMILY SSF52540 46 157 2.16E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11340 a13d247baf612f244994509d557922a4 326 PANTHER PTHR30160:SF13 1 322 3.9E-93 T 22-04-2016 TOLA_RS11340 a13d247baf612f244994509d557922a4 326 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 1 318 41.129 T 22-04-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 TOLA_RS11340 a13d247baf612f244994509d557922a4 326 Gene3D G3DSA:3.40.50.300 44 147 1.4E-5 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 Pfam PF13286 Phosphohydrolase-associated domain 407 449 3.6E-5 T 22-04-2016 IPR026875 Phosphohydrolase-associated domain TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 SUPERFAMILY SSF109604 213 329 7.85E-50 T 22-04-2016 TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 SUPERFAMILY SSF109604 363 449 7.85E-50 T 22-04-2016 TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 SUPERFAMILY SSF109604 150 183 7.85E-50 T 22-04-2016 TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 SUPERFAMILY SSF109604 25 118 7.85E-50 T 22-04-2016 TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 Pfam PF01966 HD domain 59 134 5.0E-8 T 22-04-2016 IPR006674 HD domain TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 Gene3D G3DSA:1.10.3210.10 10 106 3.9E-51 T 22-04-2016 IPR006674 HD domain TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 Gene3D G3DSA:1.10.3210.10 151 230 3.9E-51 T 22-04-2016 IPR006674 HD domain TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 26 452 9.3E-89 T 22-04-2016 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 SMART SM00471 55 244 2.6E-8 T 22-04-2016 IPR003607 HD/PDEase domain TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 PANTHER PTHR11373 26 126 2.9E-51 T 22-04-2016 TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 PANTHER PTHR11373 150 299 2.9E-51 T 22-04-2016 TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 Gene3D G3DSA:1.10.3410.10 231 340 3.0E-21 T 22-04-2016 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 Gene3D G3DSA:1.10.3550.10 107 143 5.4E-23 T 22-04-2016 IPR027432 Deoxyguanosinetriphosphate triphosphohydrolase, C-terminal domain TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 Gene3D G3DSA:1.10.3550.10 341 453 5.4E-23 T 22-04-2016 IPR027432 Deoxyguanosinetriphosphate triphosphohydrolase, C-terminal domain TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 PANTHER PTHR11373:SF29 26 126 2.9E-51 T 22-04-2016 TOLA_RS03195 44861086fa99c8044aad712914f73e89 455 PANTHER PTHR11373:SF29 150 299 2.9E-51 T 22-04-2016 TOLA_RS01680 749779a7c334268cd2928c37e773b04e 202 PANTHER PTHR10108:SF933 5 142 3.8E-14 T 22-04-2016 TOLA_RS01680 749779a7c334268cd2928c37e773b04e 202 SUPERFAMILY SSF53335 3 201 1.27E-29 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS01680 749779a7c334268cd2928c37e773b04e 202 Pfam PF13489 Methyltransferase domain 22 174 2.0E-15 T 22-04-2016 TOLA_RS01680 749779a7c334268cd2928c37e773b04e 202 PANTHER PTHR10108 5 142 3.8E-14 T 22-04-2016 TOLA_RS01680 749779a7c334268cd2928c37e773b04e 202 Gene3D G3DSA:3.40.50.150 3 201 1.4E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS03740 edaed9ce6f1d812265f062e8669d411a 140 Gene3D G3DSA:1.10.10.60 33 82 1.2E-6 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS03740 edaed9ce6f1d812265f062e8669d411a 140 Pfam PF08765 Mor transcription activator family 33 138 8.7E-30 T 22-04-2016 IPR014875 Mor transcription activator TOLA_RS03740 edaed9ce6f1d812265f062e8669d411a 140 PANTHER PTHR37812 24 139 2.1E-16 T 22-04-2016 TOLA_RS03740 edaed9ce6f1d812265f062e8669d411a 140 Gene3D G3DSA:1.10.10.60 83 139 3.7E-24 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS03740 edaed9ce6f1d812265f062e8669d411a 140 SUPERFAMILY SSF46689 34 127 3.94E-21 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS03740 edaed9ce6f1d812265f062e8669d411a 140 PANTHER PTHR37812:SF1 24 139 2.1E-16 T 22-04-2016 TOLA_RS00450 c99ab3058d521f1e6b0b04e8e85cd6f5 123 Pfam PF04024 PspC domain 6 62 2.4E-14 T 22-04-2016 IPR007168 Phage shock protein, PspC, N-terminal TOLA_RS00450 c99ab3058d521f1e6b0b04e8e85cd6f5 123 TIGRFAM TIGR02978 phageshock_pspC: phage shock protein C 6 123 8.9E-34 T 22-04-2016 IPR014320 Phage shock protein, PspC TOLA_RS01045 24c015464ee02b3e00566b1f858373e3 513 PANTHER PTHR37024 12 499 1.7E-60 T 22-04-2016 TOLA_RS01045 24c015464ee02b3e00566b1f858373e3 513 Pfam PF06812 ImpA, N-terminal, type VI secretion system 18 125 1.0E-26 T 22-04-2016 IPR010657 ImpA, N-terminal TOLA_RS01045 24c015464ee02b3e00566b1f858373e3 513 PANTHER PTHR37024:SF1 12 499 1.7E-60 T 22-04-2016 TOLA_RS01045 24c015464ee02b3e00566b1f858373e3 513 TIGRFAM TIGR03362 VI_chp_7: type VI secretion-associated protein, VC_A0119 family 19 481 1.9E-90 T 22-04-2016 IPR017739 Type VI secretion system-associated, VCA0119 TOLA_RS01045 24c015464ee02b3e00566b1f858373e3 513 Pfam PF16989 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ 223 480 2.9E-74 T 22-04-2016 IPR017739 Type VI secretion system-associated, VCA0119 TOLA_RS06860 740bbc2522933e34b554f94e16247518 169 PANTHER PTHR28255:SF1 1 167 1.8E-35 T 22-04-2016 TOLA_RS06860 740bbc2522933e34b554f94e16247518 169 SUPERFAMILY SSF143744 16 154 1.26E-22 T 22-04-2016 TOLA_RS06860 740bbc2522933e34b554f94e16247518 169 PANTHER PTHR28255 1 167 1.8E-35 T 22-04-2016 TOLA_RS06860 740bbc2522933e34b554f94e16247518 169 PIRSF PIRSF008757 1 165 2.1E-48 T 22-04-2016 IPR010371 Uncharacterised protein family UPF0303 TOLA_RS06860 740bbc2522933e34b554f94e16247518 169 Pfam PF03928 Haem-degrading 25 151 5.5E-27 T 22-04-2016 IPR005624 Haem-degrading TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PANTHER PTHR22912:SF160 1 460 3.9E-265 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 456 2.3E-34 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PIRSF PIRSF000350 1 470 3.5E-87 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 7 461 1.7E-147 T 22-04-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 3.1E-71 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 3.1E-71 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 3.1E-71 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 3.1E-71 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 3.1E-71 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 3.1E-71 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 3.1E-71 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 151 3.1E-71 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 3.1E-71 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.6E-42 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 1.6E-42 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 1.6E-42 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 1.6E-42 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 139 157 1.6E-42 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 Gene3D G3DSA:3.50.50.60 153 272 9.2E-35 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 Gene3D G3DSA:3.30.390.30 338 463 2.4E-44 T 22-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 Gene3D G3DSA:3.50.50.60 6 150 4.1E-66 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 Gene3D G3DSA:3.50.50.60 273 337 4.1E-66 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 329 2.5E-64 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 PANTHER PTHR22912 1 460 3.9E-265 T 22-04-2016 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 SUPERFAMILY SSF51905 7 382 5.7E-59 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 22-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TOLA_RS13090 a87a8a2601e44f1068777c5aa565bd79 475 SUPERFAMILY SSF55424 344 467 2.41E-38 T 22-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 TOLA_RS01660 c5d20865c8eee06c82c4c208d91e5fdd 114 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 41 89 9.7E-11 T 22-04-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS01660 c5d20865c8eee06c82c4c208d91e5fdd 114 SUPERFAMILY SSF69118 5 110 4.71E-28 T 22-04-2016 IPR029032 AhpD-like TOLA_RS01660 c5d20865c8eee06c82c4c208d91e5fdd 114 PANTHER PTHR33930:SF2 3 110 5.5E-28 T 22-04-2016 TOLA_RS01660 c5d20865c8eee06c82c4c208d91e5fdd 114 PANTHER PTHR33930 3 110 5.5E-28 T 22-04-2016 TOLA_RS01660 c5d20865c8eee06c82c4c208d91e5fdd 114 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 106 1.2E-20 T 22-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS01660 c5d20865c8eee06c82c4c208d91e5fdd 114 Gene3D G3DSA:1.20.1290.10 3 112 1.3E-34 T 22-04-2016 IPR029032 AhpD-like TOLA_RS08855 6f53bbf75aa023da44230d3b209324bc 206 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 10 206 37.679 T 22-04-2016 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19|UniPathway: UPA00031|UniPathway: UPA00031 TOLA_RS08855 6f53bbf75aa023da44230d3b209324bc 206 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 58 107 2.0E-16 T 22-04-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 TOLA_RS08855 6f53bbf75aa023da44230d3b209324bc 206 SUPERFAMILY SSF141734 11 116 3.14E-43 T 22-04-2016 TOLA_RS08855 6f53bbf75aa023da44230d3b209324bc 206 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 118 201 2.5E-32 T 22-04-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31|UniPathway: UPA00031 TOLA_RS08855 6f53bbf75aa023da44230d3b209324bc 206 SUPERFAMILY SSF101386 117 205 1.44E-25 T 22-04-2016 TOLA_RS08855 6f53bbf75aa023da44230d3b209324bc 206 PANTHER PTHR21256 12 205 2.4E-107 T 22-04-2016 TOLA_RS08855 6f53bbf75aa023da44230d3b209324bc 206 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 115 201 20.001 T 22-04-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31|UniPathway: UPA00031 TOLA_RS08855 6f53bbf75aa023da44230d3b209324bc 206 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 119 205 2.3E-18 T 22-04-2016 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31|UniPathway: UPA00031 TOLA_RS08855 6f53bbf75aa023da44230d3b209324bc 206 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 35 107 1.2E-29 T 22-04-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 Pfam PF00579 tRNA synthetases class I (W and Y) 4 285 2.1E-85 T 22-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 66 85 3.3E-28 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 195 205 3.3E-28 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 3.3E-28 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 142 163 3.3E-28 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 22-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 PANTHER PTHR10055 2 334 2.2E-182 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 331 42.171 T 22-04-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 SUPERFAMILY SSF52374 5 330 8.44E-98 T 22-04-2016 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 PANTHER PTHR10055:SF10 2 334 2.2E-182 T 22-04-2016 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 Gene3D G3DSA:1.10.240.10 206 324 3.7E-22 T 22-04-2016 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 330 1.1E-114 T 22-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 TOLA_RS13275 c8c39f82781723376cb04c625074df63 334 Gene3D G3DSA:3.40.50.620 4 205 4.3E-89 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS10715 ee09453094ae9a610d7e1ad6188d9a77 259 Gene3D G3DSA:3.40.1180.10 7 250 4.0E-101 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 TOLA_RS10715 ee09453094ae9a610d7e1ad6188d9a77 259 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 15 243 40.19 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 TOLA_RS10715 ee09453094ae9a610d7e1ad6188d9a77 259 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 188 205 - T 22-04-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 TOLA_RS10715 ee09453094ae9a610d7e1ad6188d9a77 259 PANTHER PTHR10291 6 255 5.4E-129 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 TOLA_RS10715 ee09453094ae9a610d7e1ad6188d9a77 259 SUPERFAMILY SSF64005 13 236 6.54E-90 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 TOLA_RS10715 ee09453094ae9a610d7e1ad6188d9a77 259 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 15 242 1.6E-98 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 TOLA_RS10715 ee09453094ae9a610d7e1ad6188d9a77 259 Pfam PF01255 Putative undecaprenyl diphosphate synthase 22 242 8.4E-82 T 22-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 Gene3D G3DSA:2.60.40.320 181 274 1.0E-21 T 22-04-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 13 178 1.6E-41 T 22-04-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 PANTHER PTHR10066 2 593 1.6E-272 T 22-04-2016 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 325 350 - T 22-04-2016 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 Pfam PF00703 Glycosyl hydrolases family 2 182 273 1.4E-8 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 Gene3D G3DSA:2.60.120.260 3 179 1.4E-55 T 22-04-2016 IPR008979 Galactose-binding domain-like TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 Gene3D G3DSA:3.20.20.80 276 591 7.3E-79 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 PANTHER PTHR10066:SF67 2 593 1.6E-272 T 22-04-2016 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 SUPERFAMILY SSF49303 183 274 2.3E-17 T 22-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 275 593 1.7E-89 T 22-04-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 SUPERFAMILY SSF51445 275 591 2.29E-87 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 PRINTS PR00132 Glycosyl hydrolase family 2 signature 315 333 2.1E-16 T 22-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 PRINTS PR00132 Glycosyl hydrolase family 2 signature 401 416 2.1E-16 T 22-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 PRINTS PR00132 Glycosyl hydrolase family 2 signature 500 515 2.1E-16 T 22-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 PRINTS PR00132 Glycosyl hydrolase family 2 signature 284 298 2.1E-16 T 22-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TOLA_RS14835 ad667ea5979d7c8a12a63d5f2c30b922 604 SUPERFAMILY SSF49785 2 180 1.98E-55 T 22-04-2016 IPR008979 Galactose-binding domain-like TOLA_RS12395 5ae270f45972eb72b52dad4c954043d7 125 Pfam PF09686 Plasmid protein of unknown function (Plasmid_RAQPRD) 36 109 1.3E-27 T 22-04-2016 IPR019110 Uncharacterised protein family, RAQPRD TOLA_RS12395 5ae270f45972eb72b52dad4c954043d7 125 TIGRFAM TIGR01690 ICE_RAQPRD: integrative conjugative element protein, RAQPRD family 16 111 4.8E-33 T 22-04-2016 IPR019110 Uncharacterised protein family, RAQPRD TOLA_RS08530 27167439888d2802dacbb025a7c5d208 201 SUPERFAMILY SSF53790 1 198 1.44E-36 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS08530 27167439888d2802dacbb025a7c5d208 201 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 177 1.7E-24 T 22-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 TOLA_RS08530 27167439888d2802dacbb025a7c5d208 201 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 4 195 2.5E-53 T 22-04-2016 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 TOLA_RS08530 27167439888d2802dacbb025a7c5d208 201 Gene3D G3DSA:3.40.1010.10 1 103 4.4E-23 T 22-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 TOLA_RS08530 27167439888d2802dacbb025a7c5d208 201 Gene3D G3DSA:3.30.950.10 104 198 7.6E-23 T 22-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 TOLA_RS15475 eba7bcb036810db7a2273771d07c2201 204 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 15 199 4.5E-59 T 22-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS15475 eba7bcb036810db7a2273771d07c2201 204 PANTHER PTHR18895:SF60 21 200 4.3E-49 T 22-04-2016 TOLA_RS15475 eba7bcb036810db7a2273771d07c2201 204 Pfam PF03602 Conserved hypothetical protein 95 21 197 1.8E-60 T 22-04-2016 TOLA_RS15475 eba7bcb036810db7a2273771d07c2201 204 PIRSF PIRSF004553 20 201 3.2E-54 T 22-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TOLA_RS15475 eba7bcb036810db7a2273771d07c2201 204 PANTHER PTHR18895 21 200 4.3E-49 T 22-04-2016 TOLA_RS15475 eba7bcb036810db7a2273771d07c2201 204 Gene3D G3DSA:3.40.50.150 16 200 3.3E-66 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS15475 eba7bcb036810db7a2273771d07c2201 204 SUPERFAMILY SSF53335 20 198 4.84E-48 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS11930 db1f53fc3c855d2ff8995945b680abd4 341 Pfam PF01758 Sodium Bile acid symporter family 47 242 2.1E-46 T 22-04-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 TOLA_RS11930 db1f53fc3c855d2ff8995945b680abd4 341 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 1 329 5.6E-127 T 22-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TOLA_RS11930 db1f53fc3c855d2ff8995945b680abd4 341 PIRSF PIRSF005508 1 341 7.9E-125 T 22-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TOLA_RS11930 db1f53fc3c855d2ff8995945b680abd4 341 PANTHER PTHR10361 1 340 1.2E-124 T 22-04-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 TOLA_RS11930 db1f53fc3c855d2ff8995945b680abd4 341 PANTHER PTHR10361:SF31 1 340 1.2E-124 T 22-04-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TOLA_RS09100 81a0d05201289c4778bae9121e75ab57 332 SUPERFAMILY SSF53613 12 319 2.14E-81 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS09100 81a0d05201289c4778bae9121e75ab57 332 PANTHER PTHR10584 1 332 1.2E-102 T 22-04-2016 TOLA_RS09100 81a0d05201289c4778bae9121e75ab57 332 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 265 278 - T 22-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TOLA_RS09100 81a0d05201289c4778bae9121e75ab57 332 Pfam PF00294 pfkB family carbohydrate kinase 13 313 2.1E-57 T 22-04-2016 IPR011611 Carbohydrate kinase PfkB TOLA_RS09100 81a0d05201289c4778bae9121e75ab57 332 PANTHER PTHR10584:SF186 1 332 1.2E-102 T 22-04-2016 TOLA_RS09100 81a0d05201289c4778bae9121e75ab57 332 Gene3D G3DSA:3.40.1190.20 7 321 4.6E-86 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS02545 747ac02e07c89d815381736d7498a5c6 450 Gene3D G3DSA:3.30.1850.10 1 108 3.6E-51 T 22-04-2016 IPR027820 Domain of unknown function DUF4478 TOLA_RS02545 747ac02e07c89d815381736d7498a5c6 450 Gene3D G3DSA:3.40.50.450 121 448 8.4E-122 T 22-04-2016 TOLA_RS02545 747ac02e07c89d815381736d7498a5c6 450 PANTHER PTHR31223 83 338 1.3E-162 T 22-04-2016 TOLA_RS02545 747ac02e07c89d815381736d7498a5c6 450 PANTHER PTHR31223 355 380 1.3E-162 T 22-04-2016 TOLA_RS02545 747ac02e07c89d815381736d7498a5c6 450 SUPERFAMILY SSF102405 119 325 3.36E-41 T 22-04-2016 TOLA_RS02545 747ac02e07c89d815381736d7498a5c6 450 Pfam PF14793 Domain of unknown function (DUF4478) 4 108 2.0E-47 T 22-04-2016 IPR027820 Domain of unknown function DUF4478 TOLA_RS02545 747ac02e07c89d815381736d7498a5c6 450 PANTHER PTHR31223:SF12 83 338 1.3E-162 T 22-04-2016 TOLA_RS02545 747ac02e07c89d815381736d7498a5c6 450 PANTHER PTHR31223:SF12 355 380 1.3E-162 T 22-04-2016 TOLA_RS02545 747ac02e07c89d815381736d7498a5c6 450 Pfam PF03641 Possible lysine decarboxylase 186 323 6.5E-29 T 22-04-2016 IPR031100 LOG family TOLA_RS02545 747ac02e07c89d815381736d7498a5c6 450 Pfam PF11892 Domain of unknown function (DUF3412) 329 448 8.5E-59 T 22-04-2016 IPR021826 Protein of unknown function DUF3412 TOLA_RS10250 f3952e559f92f7b5b1fa609ef575d045 171 SUPERFAMILY SSF47144 77 170 1.16E-24 T 22-04-2016 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 TOLA_RS10250 f3952e559f92f7b5b1fa609ef575d045 171 Pfam PF00226 DnaJ domain 2 70 6.2E-7 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS10250 f3952e559f92f7b5b1fa609ef575d045 171 Gene3D G3DSA:1.20.1280.20 81 170 1.3E-28 T 22-04-2016 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 TOLA_RS10250 f3952e559f92f7b5b1fa609ef575d045 171 SUPERFAMILY SSF46565 2 74 3.53E-16 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS10250 f3952e559f92f7b5b1fa609ef575d045 171 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 15 168 3.4E-46 T 22-04-2016 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 TOLA_RS10250 f3952e559f92f7b5b1fa609ef575d045 171 SMART SM00271 1 66 1.6E-8 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS10250 f3952e559f92f7b5b1fa609ef575d045 171 Gene3D G3DSA:1.10.287.110 2 78 4.4E-23 T 22-04-2016 IPR001623 DnaJ domain TOLA_RS10250 f3952e559f92f7b5b1fa609ef575d045 171 PANTHER PTHR14021:SF15 1 171 6.0E-48 T 22-04-2016 TOLA_RS10250 f3952e559f92f7b5b1fa609ef575d045 171 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 1 169 23.589 T 22-04-2016 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 TOLA_RS10250 f3952e559f92f7b5b1fa609ef575d045 171 PANTHER PTHR14021 1 171 6.0E-48 T 22-04-2016 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 TOLA_RS10250 f3952e559f92f7b5b1fa609ef575d045 171 Pfam PF07743 HSCB C-terminal oligomerisation domain 88 162 3.3E-18 T 22-04-2016 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 TOLA_RS15750 62096f3fc902d873212019b5de4ef5c2 232 SUPERFAMILY SSF53639 1 222 6.28E-64 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal TOLA_RS15750 62096f3fc902d873212019b5de4ef5c2 232 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 198 2.2E-41 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal TOLA_RS15750 62096f3fc902d873212019b5de4ef5c2 232 PANTHER PTHR22789:SF8 1 230 7.5E-136 T 22-04-2016 TOLA_RS15750 62096f3fc902d873212019b5de4ef5c2 232 PANTHER PTHR22789 1 230 7.5E-136 T 22-04-2016 TOLA_RS15750 62096f3fc902d873212019b5de4ef5c2 232 Gene3D G3DSA:3.40.225.10 2 230 1.6E-67 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal TOLA_RS15750 62096f3fc902d873212019b5de4ef5c2 232 SMART SM01007 7 198 1.6E-64 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal TOLA_RS12165 12657778c8d0cd9cf9a130448447c850 301 PANTHER PTHR10264 20 263 5.2E-47 T 22-04-2016 IPR001972 Stomatin family GO:0016020 TOLA_RS12165 12657778c8d0cd9cf9a130448447c850 301 PANTHER PTHR10264:SF78 20 263 5.2E-47 T 22-04-2016 TOLA_RS12165 12657778c8d0cd9cf9a130448447c850 301 SUPERFAMILY SSF117892 67 202 3.14E-10 T 22-04-2016 IPR001107 Band 7 domain TOLA_RS12165 12657778c8d0cd9cf9a130448447c850 301 Pfam PF01145 SPFH domain / Band 7 family 40 210 7.5E-23 T 22-04-2016 IPR001107 Band 7 domain TOLA_RS12165 12657778c8d0cd9cf9a130448447c850 301 SMART SM00244 36 197 5.6E-13 T 22-04-2016 IPR001107 Band 7 domain TOLA_RS13430 2ec3da84c3c293584807f5aeb78e6f94 329 SUPERFAMILY SSF53822 25 328 3.37E-80 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS13430 2ec3da84c3c293584807f5aeb78e6f94 329 PANTHER PTHR30036:SF2 1 328 4.5E-133 T 22-04-2016 TOLA_RS13430 2ec3da84c3c293584807f5aeb78e6f94 329 Gene3D G3DSA:3.40.50.2300 25 141 1.3E-28 T 22-04-2016 TOLA_RS13430 2ec3da84c3c293584807f5aeb78e6f94 329 PANTHER PTHR30036 1 328 4.5E-133 T 22-04-2016 TOLA_RS13430 2ec3da84c3c293584807f5aeb78e6f94 329 Pfam PF13407 Periplasmic binding protein domain 27 298 2.4E-64 T 22-04-2016 IPR025997 Periplasmic binding protein TOLA_RS13430 2ec3da84c3c293584807f5aeb78e6f94 329 Gene3D G3DSA:3.40.50.2300 142 292 6.4E-49 T 22-04-2016 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 Gene3D G3DSA:1.10.287.610 100 152 3.2E-27 T 22-04-2016 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 42.128 T 22-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 Pfam PF00318 Ribosomal protein S2 9 223 6.1E-96 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 226 1.0E-108 T 22-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 Gene3D G3DSA:3.40.50.10490 158 231 7.8E-68 T 22-04-2016 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 Gene3D G3DSA:3.40.50.10490 23 99 7.8E-68 T 22-04-2016 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 22-04-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 SUPERFAMILY SSF52313 6 228 1.44E-97 T 22-04-2016 IPR023591 Ribosomal protein S2, flavodoxin-like domain TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 PANTHER PTHR12534 1 229 4.4E-123 T 22-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 PRINTS PR00395 Ribosomal protein S2 signature 37 46 6.1E-39 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 PRINTS PR00395 Ribosomal protein S2 signature 196 210 6.1E-39 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 PRINTS PR00395 Ribosomal protein S2 signature 87 104 6.1E-39 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 PRINTS PR00395 Ribosomal protein S2 signature 175 186 6.1E-39 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 PRINTS PR00395 Ribosomal protein S2 signature 6 24 6.1E-39 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 PRINTS PR00395 Ribosomal protein S2 signature 158 175 6.1E-39 T 22-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS10735 63117a0dddf62e45410ffbb4158532ce 242 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 22-04-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TOLA_RS10125 934e485bbf37b30adda30f4b2b139e1f 336 Pfam PF00248 Aldo/keto reductase family 15 310 1.4E-62 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS10125 934e485bbf37b30adda30f4b2b139e1f 336 SUPERFAMILY SSF51430 1 313 3.93E-90 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS10125 934e485bbf37b30adda30f4b2b139e1f 336 PANTHER PTHR11732 1 336 2.7E-134 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta TOLA_RS10125 934e485bbf37b30adda30f4b2b139e1f 336 Gene3D G3DSA:3.20.20.100 10 318 4.2E-89 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS10125 934e485bbf37b30adda30f4b2b139e1f 336 PANTHER PTHR11732:SF273 1 336 2.7E-134 T 22-04-2016 TOLA_RS05035 ea28c6372699f84b09400afcfbd15159 135 Pfam PF08859 DGC domain 10 114 3.2E-32 T 22-04-2016 IPR014958 DGC TOLA_RS05035 ea28c6372699f84b09400afcfbd15159 135 PIRSF PIRSF037181 1 134 1.4E-49 T 22-04-2016 IPR014958 DGC TOLA_RS05265 1b1567067032c43e6bceb7dc74c07bb3 267 PANTHER PTHR22726 22 256 3.2E-68 T 22-04-2016 TOLA_RS05265 1b1567067032c43e6bceb7dc74c07bb3 267 Gene3D G3DSA:3.30.2010.10 55 141 8.6E-19 T 22-04-2016 TOLA_RS05265 1b1567067032c43e6bceb7dc74c07bb3 267 Pfam PF01435 Peptidase family M48 65 244 1.5E-39 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TOLA_RS09450 7fd7e74d0b00f266073e21a43271c7a3 273 PANTHER PTHR18966 33 254 5.7E-28 T 22-04-2016 TOLA_RS09450 7fd7e74d0b00f266073e21a43271c7a3 273 PANTHER PTHR18966:SF191 33 254 5.7E-28 T 22-04-2016 TOLA_RS09450 7fd7e74d0b00f266073e21a43271c7a3 273 Gene3D G3DSA:3.40.190.10 108 215 1.0E-11 T 22-04-2016 TOLA_RS09450 7fd7e74d0b00f266073e21a43271c7a3 273 SUPERFAMILY SSF53850 8 255 5.51E-42 T 22-04-2016 TOLA_RS09450 7fd7e74d0b00f266073e21a43271c7a3 273 Gene3D G3DSA:3.40.190.10 30 107 2.8E-24 T 22-04-2016 TOLA_RS09450 7fd7e74d0b00f266073e21a43271c7a3 273 Gene3D G3DSA:3.40.190.10 218 256 2.8E-24 T 22-04-2016 TOLA_RS09450 7fd7e74d0b00f266073e21a43271c7a3 273 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 255 8.2E-41 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS09450 7fd7e74d0b00f266073e21a43271c7a3 273 SMART SM00062 32 258 1.1E-24 T 22-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 Gene3D G3DSA:1.10.3860.10 1 408 1.4E-114 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 Pfam PF00375 Sodium:dicarboxylate symporter family 6 402 1.7E-108 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 PRINTS PR00173 Glutamate-aspartate symporter signature 357 377 3.2E-42 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 PRINTS PR00173 Glutamate-aspartate symporter signature 330 349 3.2E-42 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 PRINTS PR00173 Glutamate-aspartate symporter signature 195 214 3.2E-42 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 PRINTS PR00173 Glutamate-aspartate symporter signature 148 170 3.2E-42 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 3.2E-42 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 PRINTS PR00173 Glutamate-aspartate symporter signature 51 71 3.2E-42 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 PRINTS PR00173 Glutamate-aspartate symporter signature 295 321 3.2E-42 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 3.2E-42 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 PANTHER PTHR11958:SF26 1 409 9.5E-164 T 22-04-2016 IPR033380 Glutamate-aspartate symport protein GltP/GltT GO:0015293|GO:0015810|GO:0015813|GO:0016021 TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 SUPERFAMILY SSF118215 6 404 7.85E-113 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS01005 9a16cc787d1773e56f6210022a3f4227 430 PANTHER PTHR11958 1 409 9.5E-164 T 22-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 TOLA_RS10725 0dd5e1cb532442ab2f86a60485be30f0 244 Hamap MF_01220_B Uridylate kinase [pyrH]. 7 240 43.098 T 22-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 TOLA_RS10725 0dd5e1cb532442ab2f86a60485be30f0 244 PANTHER PTHR21499 9 239 2.1E-109 T 22-04-2016 TOLA_RS10725 0dd5e1cb532442ab2f86a60485be30f0 244 PIRSF PIRSF005650 4 244 9.7E-89 T 22-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 TOLA_RS10725 0dd5e1cb532442ab2f86a60485be30f0 244 PANTHER PTHR21499:SF23 9 239 2.1E-109 T 22-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 TOLA_RS10725 0dd5e1cb532442ab2f86a60485be30f0 244 Pfam PF00696 Amino acid kinase family 10 219 1.8E-26 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS10725 0dd5e1cb532442ab2f86a60485be30f0 244 Gene3D G3DSA:3.40.1160.10 4 240 4.4E-85 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS10725 0dd5e1cb532442ab2f86a60485be30f0 244 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 240 3.8E-101 T 22-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 TOLA_RS10725 0dd5e1cb532442ab2f86a60485be30f0 244 SUPERFAMILY SSF53633 8 240 2.75E-71 T 22-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 TOLA_RS14080 306d1df248484ced3b0a94ca7ac255a0 123 PANTHER PTHR33747:SF1 1 123 1.9E-14 T 22-04-2016 TOLA_RS14080 306d1df248484ced3b0a94ca7ac255a0 123 SUPERFAMILY SSF54427 1 95 1.4E-23 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS14080 306d1df248484ced3b0a94ca7ac255a0 123 SUPERFAMILY SSF103642 103 123 1.96E-7 T 22-04-2016 TOLA_RS14080 306d1df248484ced3b0a94ca7ac255a0 123 PANTHER PTHR33747 1 123 1.9E-14 T 22-04-2016 TOLA_RS14080 306d1df248484ced3b0a94ca7ac255a0 123 Pfam PF02810 SEC-C motif 107 123 1.7E-9 T 22-04-2016 IPR004027 SEC-C motif TOLA_RS14080 306d1df248484ced3b0a94ca7ac255a0 123 Gene3D G3DSA:3.10.450.50 1 123 3.9E-35 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS04215 1b4e2158655cbdd4e7e11c2b69d9a236 282 PANTHER PTHR18895:SF64 1 276 1.2E-106 T 22-04-2016 TOLA_RS04215 1b4e2158655cbdd4e7e11c2b69d9a236 282 Pfam PF05175 Methyltransferase small domain 106 191 9.5E-16 T 22-04-2016 IPR007848 Methyltransferase small domain GO:0008168 TOLA_RS04215 1b4e2158655cbdd4e7e11c2b69d9a236 282 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 23 272 6.6E-92 T 22-04-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 TOLA_RS04215 1b4e2158655cbdd4e7e11c2b69d9a236 282 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 9 274 1.3E-76 T 22-04-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 TOLA_RS04215 1b4e2158655cbdd4e7e11c2b69d9a236 282 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 181 187 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TOLA_RS04215 1b4e2158655cbdd4e7e11c2b69d9a236 282 PANTHER PTHR18895 1 276 1.2E-106 T 22-04-2016 TOLA_RS04215 1b4e2158655cbdd4e7e11c2b69d9a236 282 Gene3D G3DSA:3.40.50.150 86 276 7.0E-67 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04215 1b4e2158655cbdd4e7e11c2b69d9a236 282 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 276 44.459 T 22-04-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 TOLA_RS04215 1b4e2158655cbdd4e7e11c2b69d9a236 282 SUPERFAMILY SSF53335 4 273 7.49E-56 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04215 1b4e2158655cbdd4e7e11c2b69d9a236 282 Gene3D G3DSA:1.10.8.10 1 84 7.4E-27 T 22-04-2016 TOLA_RS01380 ad087e1508daa0b482d083da86736122 174 PANTHER PTHR38101:SF1 8 173 4.3E-61 T 22-04-2016 TOLA_RS01380 ad087e1508daa0b482d083da86736122 174 SUPERFAMILY SSF158710 27 170 2.09E-49 T 22-04-2016 TOLA_RS01380 ad087e1508daa0b482d083da86736122 174 Gene3D G3DSA:1.10.60.30 103 173 1.0E-27 T 22-04-2016 IPR023153 PSPTO4464-like domain TOLA_RS01380 ad087e1508daa0b482d083da86736122 174 Pfam PF04751 Protein of unknown function (DUF615) 15 167 3.9E-53 T 22-04-2016 IPR006839 Ribosome-associated, YjgA TOLA_RS01380 ad087e1508daa0b482d083da86736122 174 PANTHER PTHR38101 8 173 4.3E-61 T 22-04-2016 TOLA_RS01380 ad087e1508daa0b482d083da86736122 174 PIRSF PIRSF016183 1 174 3.5E-61 T 22-04-2016 IPR006839 Ribosome-associated, YjgA TOLA_RS01380 ad087e1508daa0b482d083da86736122 174 Gene3D G3DSA:1.10.60.30 26 100 1.1E-27 T 22-04-2016 IPR023153 PSPTO4464-like domain TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 132 141 2.3E-6 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 107 126 2.3E-6 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 31 41 2.3E-6 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 47 54 2.3E-6 T 22-04-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 SUPERFAMILY SSF52343 100 230 3.93E-34 T 22-04-2016 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 Pfam PF00970 Oxidoreductase FAD-binding domain 22 96 1.0E-5 T 22-04-2016 IPR008333 Oxidoreductase, FAD-binding domain TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 SUPERFAMILY SSF63380 8 97 2.32E-17 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 Gene3D G3DSA:3.40.50.80 100 230 1.8E-34 T 22-04-2016 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 PANTHER PTHR19370:SF119 6 232 8.7E-79 T 22-04-2016 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 PRINTS PR00410 Phenol hydroxylase reductase family signature 31 43 4.7E-14 T 22-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 PRINTS PR00410 Phenol hydroxylase reductase family signature 91 100 4.7E-14 T 22-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 141 4.7E-14 T 22-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 PRINTS PR00410 Phenol hydroxylase reductase family signature 47 54 4.7E-14 T 22-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 PRINTS PR00410 Phenol hydroxylase reductase family signature 107 126 4.7E-14 T 22-04-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 Pfam PF00175 Oxidoreductase NAD-binding domain 108 211 4.3E-18 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 Gene3D G3DSA:2.40.30.10 6 98 2.0E-22 T 22-04-2016 TOLA_RS15280 95488af005a3b44f3b7cf4b19d9eafdd 232 PANTHER PTHR19370 6 232 8.7E-79 T 22-04-2016 TOLA_RS11575 377829c361a193961499a37c1826b94f 327 Pfam PF09588 YqaJ-like viral recombinase domain 22 157 1.4E-33 T 22-04-2016 IPR019080 YqaJ viral recombinase TOLA_RS11575 377829c361a193961499a37c1826b94f 327 Gene3D G3DSA:3.90.320.10 15 201 1.0E-34 T 22-04-2016 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 TOLA_RS11575 377829c361a193961499a37c1826b94f 327 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 16 168 2.1E-40 T 22-04-2016 IPR017482 Putative phage-type endonuclease TOLA_RS11575 377829c361a193961499a37c1826b94f 327 SUPERFAMILY SSF52980 9 202 2.68E-40 T 22-04-2016 IPR011335 Restriction endonuclease type II-like TOLA_RS02045 b4abf8fdb0cd03723068bea4179625b8 318 Gene3D G3DSA:2.40.50.100 33 65 8.0E-11 T 22-04-2016 TOLA_RS02045 b4abf8fdb0cd03723068bea4179625b8 318 Gene3D G3DSA:2.40.50.100 192 223 8.0E-11 T 22-04-2016 TOLA_RS02045 b4abf8fdb0cd03723068bea4179625b8 318 PANTHER PTHR32347 1 315 7.0E-59 T 22-04-2016 TOLA_RS02045 b4abf8fdb0cd03723068bea4179625b8 318 Pfam PF13533 Biotin-lipoyl like 33 82 1.4E-9 T 22-04-2016 TOLA_RS02045 b4abf8fdb0cd03723068bea4179625b8 318 SUPERFAMILY SSF111369 31 87 3.66E-7 T 22-04-2016 TOLA_RS02045 b4abf8fdb0cd03723068bea4179625b8 318 Pfam PF13437 HlyD family secretion protein 197 306 7.0E-18 T 22-04-2016 TOLA_RS02045 b4abf8fdb0cd03723068bea4179625b8 318 PANTHER PTHR32347:SF15 1 315 7.0E-59 T 22-04-2016 TOLA_RS05955 6e8164012907563f791b0c1a0bc2dd66 375 Pfam PF09623 CRISPR-associated protein NE0113 (Cas_NE0113) 12 224 3.6E-56 T 22-04-2016 IPR019092 CRISPR-assoc protein, NE0113/Csx13 TOLA_RS05955 6e8164012907563f791b0c1a0bc2dd66 375 TIGRFAM TIGR02584 cas_NE0113: CRISPR-associated protein, NE0113 family 4 202 2.0E-65 T 22-04-2016 IPR013413 CRISPR-associated protein, NE0113 TOLA_RS09010 cd31b44c4c3c88a897f517b03674b814 186 SMART SM01012 126 181 2.2E-16 T 22-04-2016 IPR005561 ANTAR domain GO:0003723 TOLA_RS09010 cd31b44c4c3c88a897f517b03674b814 186 Gene3D G3DSA:1.10.10.10 129 183 1.5E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09010 cd31b44c4c3c88a897f517b03674b814 186 SUPERFAMILY SSF52172 4 181 4.22E-20 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS09010 cd31b44c4c3c88a897f517b03674b814 186 Pfam PF03861 ANTAR domain 129 181 4.1E-15 T 22-04-2016 IPR005561 ANTAR domain GO:0003723 TOLA_RS15310 b033ce01c17248e4373348ca8e66b238 434 PIRSF PIRSF006351 2 432 7.8E-136 T 22-04-2016 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 TOLA_RS15310 b033ce01c17248e4373348ca8e66b238 434 PANTHER PTHR33989 1 433 3.3E-152 T 22-04-2016 TOLA_RS15310 b033ce01c17248e4373348ca8e66b238 434 Pfam PF02378 Phosphotransferase system, EIIC 30 349 1.6E-53 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS15310 b033ce01c17248e4373348ca8e66b238 434 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 14 424 3.0E-111 T 22-04-2016 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 TOLA_RS15310 b033ce01c17248e4373348ca8e66b238 434 PANTHER PTHR33989:SF4 1 433 3.3E-152 T 22-04-2016 TOLA_RS15545 ecb1c4ce05c0b01e418007f564e36b24 181 PIRSF PIRSF011443 11 181 6.4E-53 T 22-04-2016 IPR026267 Inner membrane protein YgjV TOLA_RS15545 ecb1c4ce05c0b01e418007f564e36b24 181 Pfam PF10688 Bacterial inner membrane protein 16 172 1.5E-51 T 22-04-2016 IPR019629 Uncharacterised protein family HI1736/YgjV TOLA_RS00540 0b8dc39bccdef809230dab8a9f8a83d4 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 6.6E-47 T 22-04-2016 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 TOLA_RS00540 0b8dc39bccdef809230dab8a9f8a83d4 92 PIRSF PIRSF002144 1 92 3.7E-32 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00540 0b8dc39bccdef809230dab8a9f8a83d4 92 Gene3D G3DSA:3.30.860.10 1 91 1.7E-41 T 22-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 TOLA_RS00540 0b8dc39bccdef809230dab8a9f8a83d4 92 PANTHER PTHR11880 1 92 7.3E-58 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00540 0b8dc39bccdef809230dab8a9f8a83d4 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 22-04-2016 IPR020934 Ribosomal protein S19 conserved site GO:0003723 TOLA_RS00540 0b8dc39bccdef809230dab8a9f8a83d4 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.866 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00540 0b8dc39bccdef809230dab8a9f8a83d4 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 5.0E-25 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00540 0b8dc39bccdef809230dab8a9f8a83d4 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 5.0E-25 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00540 0b8dc39bccdef809230dab8a9f8a83d4 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 5.0E-25 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 TOLA_RS00540 0b8dc39bccdef809230dab8a9f8a83d4 92 SUPERFAMILY SSF54570 3 84 3.01E-35 T 22-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 TOLA_RS00540 0b8dc39bccdef809230dab8a9f8a83d4 92 Pfam PF00203 Ribosomal protein S19 3 83 1.1E-37 T 22-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 121 314 2.0E-45 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 PANTHER PTHR30620:SF18 656 808 5.6E-215 T 22-04-2016 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 PANTHER PTHR30620:SF18 49 71 5.6E-215 T 22-04-2016 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 PANTHER PTHR30620:SF18 484 630 5.6E-215 T 22-04-2016 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 PANTHER PTHR30620:SF18 106 463 5.6E-215 T 22-04-2016 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 SUPERFAMILY SSF51445 40 403 1.37E-83 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 PRINTS PR00133 Glycosyl hydrolase family 3 signature 196 212 2.1E-22 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 PRINTS PR00133 Glycosyl hydrolase family 3 signature 227 243 2.1E-22 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 PRINTS PR00133 Glycosyl hydrolase family 3 signature 297 315 2.1E-22 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 PRINTS PR00133 Glycosyl hydrolase family 3 signature 111 127 2.1E-22 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 Pfam PF14310 Fibronectin type III-like domain 724 795 2.7E-21 T 22-04-2016 IPR026891 Fibronectin type III-like domain TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 PANTHER PTHR30620 656 808 5.6E-215 T 22-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 PANTHER PTHR30620 49 71 5.6E-215 T 22-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 PANTHER PTHR30620 484 630 5.6E-215 T 22-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 PANTHER PTHR30620 106 463 5.6E-215 T 22-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 404 684 5.5E-40 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 Gene3D G3DSA:3.20.20.300 43 375 1.1E-89 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 SMART SM01217 724 795 1.7E-25 T 22-04-2016 IPR026891 Fibronectin type III-like domain TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 SUPERFAMILY SSF52279 501 618 6.02E-39 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 SUPERFAMILY SSF52279 665 687 6.02E-39 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 SUPERFAMILY SSF52279 404 474 6.02E-39 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 Gene3D G3DSA:3.40.50.1700 392 466 1.4E-49 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 Gene3D G3DSA:3.40.50.1700 498 618 1.4E-49 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS08715 93d68bbfc38000b575bb6495ec450642 837 Gene3D G3DSA:3.40.50.1700 665 683 1.4E-49 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 PANTHER PTHR22777:SF14 1 513 3.4E-206 T 22-04-2016 TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 Pfam PF00571 CBS domain 309 361 7.6E-5 T 22-04-2016 IPR000644 CBS domain TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 Pfam PF00571 CBS domain 374 422 2.7E-7 T 22-04-2016 IPR000644 CBS domain TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 SMART SM00116 374 422 6.0 T 22-04-2016 IPR000644 CBS domain TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 SMART SM00116 311 361 0.51 T 22-04-2016 IPR000644 CBS domain TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 Gene3D G3DSA:3.10.580.10 288 416 3.2E-17 T 22-04-2016 TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 PANTHER PTHR22777 1 513 3.4E-206 T 22-04-2016 TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 Pfam PF03471 Transporter associated domain 437 514 1.3E-18 T 22-04-2016 IPR005170 Transporter-associated domain TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 SUPERFAMILY SSF56176 431 513 4.36E-18 T 22-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 Gene3D G3DSA:3.30.465.10 417 513 1.7E-21 T 22-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 SUPERFAMILY SSF54631 289 424 1.39E-24 T 22-04-2016 TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 SMART SM01091 436 515 1.6E-20 T 22-04-2016 IPR005170 Transporter-associated domain TOLA_RS04000 a87f3ad9191367c1893831436bb7c35e 517 Pfam PF03741 Integral membrane protein TerC family 15 204 3.4E-48 T 22-04-2016 IPR005496 Integral membrane protein TerC GO:0016021 TOLA_RS14060 7c0663a5211d723872c8c8b26d095d90 79 ProDom PD026997 UPF0270 YHEU SO0879 3D-STRUCTURE LYASE PLU0398 YPO0179/Y3960/YP0178 ENOLASE HD0737 PSPTO1630 1 68 1.0E-20 T 22-04-2016 IPR010648 Uncharacterised protein family UPF0270 TOLA_RS14060 7c0663a5211d723872c8c8b26d095d90 79 SUPERFAMILY SSF118001 1 70 3.4E-27 T 22-04-2016 IPR010648 Uncharacterised protein family UPF0270 TOLA_RS14060 7c0663a5211d723872c8c8b26d095d90 79 Pfam PF06794 Uncharacterised protein family (UPF0270) 1 68 7.8E-34 T 22-04-2016 IPR010648 Uncharacterised protein family UPF0270 TOLA_RS14060 7c0663a5211d723872c8c8b26d095d90 79 PIRSF PIRSF006169 1 73 2.0E-33 T 22-04-2016 IPR010648 Uncharacterised protein family UPF0270 TOLA_RS14060 7c0663a5211d723872c8c8b26d095d90 79 Gene3D G3DSA:1.10.10.610 1 71 4.8E-34 T 22-04-2016 IPR010648 Uncharacterised protein family UPF0270 TOLA_RS02915 3cda3aaf776b4112beb15a2a0609e57b 462 PANTHER PTHR30330:SF3 1 445 1.6E-210 T 22-04-2016 TOLA_RS02915 3cda3aaf776b4112beb15a2a0609e57b 462 Pfam PF01235 Sodium:alanine symporter family 56 451 2.6E-142 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS02915 3cda3aaf776b4112beb15a2a0609e57b 462 PANTHER PTHR30330 1 445 1.6E-210 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS02915 3cda3aaf776b4112beb15a2a0609e57b 462 PRINTS PR00175 Sodium/alanine symporter signature 93 115 1.3E-51 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS02915 3cda3aaf776b4112beb15a2a0609e57b 462 PRINTS PR00175 Sodium/alanine symporter signature 309 327 1.3E-51 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS02915 3cda3aaf776b4112beb15a2a0609e57b 462 PRINTS PR00175 Sodium/alanine symporter signature 214 233 1.3E-51 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS02915 3cda3aaf776b4112beb15a2a0609e57b 462 PRINTS PR00175 Sodium/alanine symporter signature 353 375 1.3E-51 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS02915 3cda3aaf776b4112beb15a2a0609e57b 462 PRINTS PR00175 Sodium/alanine symporter signature 186 204 1.3E-51 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS02915 3cda3aaf776b4112beb15a2a0609e57b 462 PRINTS PR00175 Sodium/alanine symporter signature 412 432 1.3E-51 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS02915 3cda3aaf776b4112beb15a2a0609e57b 462 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 443 1.2E-146 T 22-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TOLA_RS02765 ccc03a405cda1c64d9d878b325196e32 205 PANTHER PTHR10695 1 184 2.9E-76 T 22-04-2016 TOLA_RS02765 ccc03a405cda1c64d9d878b325196e32 205 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 3 184 2.4E-61 T 22-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 TOLA_RS02765 ccc03a405cda1c64d9d878b325196e32 205 Pfam PF01121 Dephospho-CoA kinase 3 176 1.0E-70 T 22-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 TOLA_RS02765 ccc03a405cda1c64d9d878b325196e32 205 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 193 27.84 T 22-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 TOLA_RS02765 ccc03a405cda1c64d9d878b325196e32 205 SUPERFAMILY SSF52540 1 184 1.12E-40 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02765 ccc03a405cda1c64d9d878b325196e32 205 Gene3D G3DSA:3.40.50.300 1 196 3.0E-73 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10945 559b901658daecac60dd9822581550a9 173 Pfam PF13420 Acetyltransferase (GNAT) domain 12 156 2.6E-17 T 22-04-2016 TOLA_RS10945 559b901658daecac60dd9822581550a9 173 PANTHER PTHR23091:SF187 1 172 7.8E-71 T 22-04-2016 TOLA_RS10945 559b901658daecac60dd9822581550a9 173 SUPERFAMILY SSF55729 9 164 3.66E-31 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS10945 559b901658daecac60dd9822581550a9 173 Gene3D G3DSA:3.40.630.30 9 165 2.5E-35 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS10945 559b901658daecac60dd9822581550a9 173 PANTHER PTHR23091 1 172 7.8E-71 T 22-04-2016 TOLA_RS07370 d64c071c344faef594335af7bc2063d6 223 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 2 202 1.9E-83 T 22-04-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 TOLA_RS07370 d64c071c344faef594335af7bc2063d6 223 Pfam PF02508 Rnf-Nqr subunit, membrane protein 2 194 2.3E-66 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 TOLA_RS07370 d64c071c344faef594335af7bc2063d6 223 PANTHER PTHR30586 1 214 3.3E-125 T 22-04-2016 TOLA_RS07370 d64c071c344faef594335af7bc2063d6 223 Hamap MF_00478 Electron transport complex subunit RsxE [rsxE]. 1 204 27.021 T 22-04-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 TOLA_RS07370 d64c071c344faef594335af7bc2063d6 223 PIRSF PIRSF006102 1 212 4.5E-77 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 TOLA_RS07370 d64c071c344faef594335af7bc2063d6 223 PANTHER PTHR30586:SF0 1 214 3.3E-125 T 22-04-2016 IPR010968 Electron transport complex, RsxE GO:0016020|GO:0022900 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 SUPERFAMILY SSF54680 421 497 4.45E-14 T 22-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 SMART SM00941 434 501 8.2E-15 T 22-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 207 222 - T 22-04-2016 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 437 495 2.4E-8 T 22-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 Gene3D G3DSA:3.90.1170.30 419 496 1.9E-13 T 22-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 Gene3D G3DSA:3.40.1030.10 167 417 2.8E-71 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 Pfam PF00591 Glycosyl transferase family, a/b domain 173 401 1.1E-14 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 SUPERFAMILY SSF47648 101 167 9.94E-13 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 Pfam PF02885 Glycosyl transferase family, helical bundle domain 109 162 1.0E-8 T 22-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 Hamap MF_00703 Putative thymidine phosphorylase. 13 505 64.053 T 22-04-2016 IPR028579 Putative thymidine phosphorylase KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 Gene3D G3DSA:1.20.970.10 101 165 1.7E-13 T 22-04-2016 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 SUPERFAMILY SSF52418 167 419 3.4E-71 T 22-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 PANTHER PTHR10515 75 505 1.5E-120 T 22-04-2016 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 PANTHER PTHR10515:SF0 75 505 1.5E-120 T 22-04-2016 TOLA_RS12620 2f8d21e47493ac610cc03ddebf524b83 505 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 16 495 5.0E-175 T 22-04-2016 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 TOLA_RS16135 be1986f9f4d6b6ed0ab0cf30dbe61ae6 151 PRINTS PR00369 Flavodoxin signature 55 66 4.1E-8 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TOLA_RS16135 be1986f9f4d6b6ed0ab0cf30dbe61ae6 151 PRINTS PR00369 Flavodoxin signature 5 18 4.1E-8 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TOLA_RS16135 be1986f9f4d6b6ed0ab0cf30dbe61ae6 151 PRINTS PR00369 Flavodoxin signature 86 96 4.1E-8 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TOLA_RS16135 be1986f9f4d6b6ed0ab0cf30dbe61ae6 151 PRINTS PR00369 Flavodoxin signature 110 129 4.1E-8 T 22-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 TOLA_RS16135 be1986f9f4d6b6ed0ab0cf30dbe61ae6 151 Pfam PF00258 Flavodoxin 6 142 5.2E-26 T 22-04-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 TOLA_RS16135 be1986f9f4d6b6ed0ab0cf30dbe61ae6 151 PANTHER PTHR19384:SF81 1 151 2.0E-37 T 22-04-2016 TOLA_RS16135 be1986f9f4d6b6ed0ab0cf30dbe61ae6 151 PANTHER PTHR19384 1 151 2.0E-37 T 22-04-2016 TOLA_RS16135 be1986f9f4d6b6ed0ab0cf30dbe61ae6 151 SUPERFAMILY SSF52218 1 147 2.67E-39 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS16135 be1986f9f4d6b6ed0ab0cf30dbe61ae6 151 Gene3D G3DSA:3.40.50.360 1 146 3.1E-39 T 22-04-2016 IPR029039 Flavoprotein-like domain TOLA_RS15905 432fc3aa628ad1cecadef48fa5e28194 490 Gene3D G3DSA:1.20.1250.20 270 423 1.8E-6 T 22-04-2016 TOLA_RS15905 432fc3aa628ad1cecadef48fa5e28194 490 Gene3D G3DSA:1.20.1250.20 21 191 4.2E-14 T 22-04-2016 TOLA_RS15905 432fc3aa628ad1cecadef48fa5e28194 490 Pfam PF07690 Major Facilitator Superfamily 21 383 6.6E-25 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS15905 432fc3aa628ad1cecadef48fa5e28194 490 PANTHER PTHR23501 9 489 8.4E-32 T 22-04-2016 TOLA_RS15905 432fc3aa628ad1cecadef48fa5e28194 490 SUPERFAMILY SSF103473 253 424 4.84E-34 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS15905 432fc3aa628ad1cecadef48fa5e28194 490 SUPERFAMILY SSF103473 13 200 4.84E-34 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS05510 803b04b5bc10ac10557120fc03e8d199 264 Pfam PF00899 ThiF family 13 243 4.2E-55 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TOLA_RS05510 803b04b5bc10ac10557120fc03e8d199 264 SUPERFAMILY SSF69572 4 246 1.96E-73 T 22-04-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TOLA_RS05510 803b04b5bc10ac10557120fc03e8d199 264 PANTHER PTHR10953 1 246 4.8E-101 T 22-04-2016 TOLA_RS05510 803b04b5bc10ac10557120fc03e8d199 264 PANTHER PTHR10953:SF158 1 246 4.8E-101 T 22-04-2016 TOLA_RS05510 803b04b5bc10ac10557120fc03e8d199 264 Gene3D G3DSA:3.40.50.720 5 247 1.1E-65 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS04555 ba41d34831cad4b961f45baf4729bd2e 375 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 10 350 2.5E-128 T 22-04-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 TOLA_RS04555 ba41d34831cad4b961f45baf4729bd2e 375 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 8 360 34.907 T 22-04-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 TOLA_RS04555 ba41d34831cad4b961f45baf4729bd2e 375 SUPERFAMILY SSF56014 267 354 7.07E-12 T 22-04-2016 TOLA_RS04555 ba41d34831cad4b961f45baf4729bd2e 375 Pfam PF04551 GcpE protein 14 354 7.4E-134 T 22-04-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 TOLA_RS04555 ba41d34831cad4b961f45baf4729bd2e 375 SUPERFAMILY SSF51717 16 209 2.51E-10 T 22-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 TOLA_RS04555 ba41d34831cad4b961f45baf4729bd2e 375 PIRSF PIRSF004640 2 364 1.3E-147 T 22-04-2016 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 TOLA_RS04555 ba41d34831cad4b961f45baf4729bd2e 375 PANTHER PTHR30454 3 370 6.7E-215 T 22-04-2016 TOLA_RS04555 ba41d34831cad4b961f45baf4729bd2e 375 Gene3D G3DSA:3.20.20.70 32 133 2.5E-8 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS15375 924c47a19bd0480ebd5c3cc28ff0e072 257 SMART SM00900 142 240 3.2E-27 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 TOLA_RS15375 924c47a19bd0480ebd5c3cc28ff0e072 257 TIGRFAM TIGR01938 nqrC: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit 6 248 2.4E-83 T 22-04-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 TOLA_RS15375 924c47a19bd0480ebd5c3cc28ff0e072 257 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 6 252 35.722 T 22-04-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 TOLA_RS15375 924c47a19bd0480ebd5c3cc28ff0e072 257 PIRSF PIRSF009437 1 255 2.8E-95 T 22-04-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 TOLA_RS15375 924c47a19bd0480ebd5c3cc28ff0e072 257 PANTHER PTHR37838:SF1 1 257 2.2E-95 T 22-04-2016 TOLA_RS15375 924c47a19bd0480ebd5c3cc28ff0e072 257 Pfam PF04205 FMN-binding domain 142 234 3.4E-14 T 22-04-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 TOLA_RS15375 924c47a19bd0480ebd5c3cc28ff0e072 257 PANTHER PTHR37838 1 257 2.2E-95 T 22-04-2016 TOLA_RS15050 df2a0891a2a846d6817968065711e0f5 185 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 24 136 1.6E-12 T 22-04-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA TOLA_RS15050 df2a0891a2a846d6817968065711e0f5 185 Gene3D G3DSA:3.40.50.1000 15 174 8.7E-47 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS15050 df2a0891a2a846d6817968065711e0f5 185 Pfam PF08282 haloacid dehalogenase-like hydrolase 92 157 5.2E-9 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS15050 df2a0891a2a846d6817968065711e0f5 185 SUPERFAMILY SSF56784 21 177 5.73E-43 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS15050 df2a0891a2a846d6817968065711e0f5 185 PANTHER PTHR21485 16 178 9.9E-57 T 22-04-2016 TOLA_RS15050 df2a0891a2a846d6817968065711e0f5 185 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 23 174 4.9E-57 T 22-04-2016 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 TOLA_RS15050 df2a0891a2a846d6817968065711e0f5 185 PIRSF PIRSF006118 10 185 5.6E-70 T 22-04-2016 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 TOLA_RS13515 a79229f24fbaf329f63512a5236ef2e5 527 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 463 480 - T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS13515 a79229f24fbaf329f63512a5236ef2e5 527 Pfam PF02378 Phosphotransferase system, EIIC 10 345 1.7E-74 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS13515 a79229f24fbaf329f63512a5236ef2e5 527 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 408 510 1.3E-23 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS13515 a79229f24fbaf329f63512a5236ef2e5 527 PANTHER PTHR30009:SF12 2 526 1.1E-272 T 22-04-2016 TOLA_RS13515 a79229f24fbaf329f63512a5236ef2e5 527 PANTHER PTHR30009 2 526 1.1E-272 T 22-04-2016 TOLA_RS13515 a79229f24fbaf329f63512a5236ef2e5 527 Gene3D G3DSA:3.30.1360.60 447 525 5.6E-26 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS13515 a79229f24fbaf329f63512a5236ef2e5 527 TIGRFAM TIGR02005 PTS-IIBC-alpha: PTS system, alpha-glucoside-specific IIBC component 3 524 7.6E-266 T 22-04-2016 IPR010975 Phosphotransferase system, alpha-glucoside-specific IIBC component GO:0008982|GO:0009401 TOLA_RS13515 a79229f24fbaf329f63512a5236ef2e5 527 SUPERFAMILY SSF55604 450 524 7.72E-19 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS13515 a79229f24fbaf329f63512a5236ef2e5 527 Pfam PF00367 phosphotransferase system, EIIB 453 484 1.3E-13 T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS15855 9a4661f7b4cb1dbf1ff279ee078cc15d 175 Pfam PF05618 Putative ATP-dependant zinc protease 35 168 1.3E-37 T 22-04-2016 TOLA_RS15855 9a4661f7b4cb1dbf1ff279ee078cc15d 175 SUPERFAMILY SSF50630 35 168 2.64E-36 T 22-04-2016 IPR021109 Aspartic peptidase domain TOLA_RS15855 9a4661f7b4cb1dbf1ff279ee078cc15d 175 PANTHER PTHR38037 27 175 4.2E-39 T 22-04-2016 TOLA_RS15855 9a4661f7b4cb1dbf1ff279ee078cc15d 175 Gene3D G3DSA:2.40.70.10 34 162 2.4E-36 T 22-04-2016 IPR021109 Aspartic peptidase domain TOLA_RS12675 b7a2ec3db11f7071fe82d7bbeb84c913 291 PANTHER PTHR10067 2 290 2.9E-111 T 22-04-2016 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 TOLA_RS12675 b7a2ec3db11f7071fe82d7bbeb84c913 291 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 51 283 2.6E-84 T 22-04-2016 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 TOLA_RS12675 b7a2ec3db11f7071fe82d7bbeb84c913 291 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 12 286 47.696 T 22-04-2016 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 TOLA_RS12675 b7a2ec3db11f7071fe82d7bbeb84c913 291 Pfam PF02666 Phosphatidylserine decarboxylase 65 282 5.5E-61 T 22-04-2016 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 TOLA_RS03665 d0aa41437a2f8a4f4f6a1ff8bd14b96b 741 Pfam PF00665 Integrase core domain 287 401 7.1E-18 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 TOLA_RS03665 d0aa41437a2f8a4f4f6a1ff8bd14b96b 741 Pfam PF02316 Mu DNA-binding domain 9 69 2.8E-15 T 22-04-2016 IPR003314 Mu-type HTH domain GO:0003677 TOLA_RS03665 d0aa41437a2f8a4f4f6a1ff8bd14b96b 741 SUPERFAMILY SSF46955 1 68 1.65E-15 T 22-04-2016 IPR009061 Putative DNA-binding domain TOLA_RS03665 d0aa41437a2f8a4f4f6a1ff8bd14b96b 741 Pfam PF09299 Mu transposase, C-terminal 504 553 2.6E-4 T 22-04-2016 IPR015378 Transposase-like, Mu, C-terminal TOLA_RS03665 d0aa41437a2f8a4f4f6a1ff8bd14b96b 741 Gene3D G3DSA:1.10.10.10 1 67 5.5E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS03665 d0aa41437a2f8a4f4f6a1ff8bd14b96b 741 SUPERFAMILY SSF53098 285 407 2.28E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS03665 d0aa41437a2f8a4f4f6a1ff8bd14b96b 741 SUPERFAMILY SSF53098 444 480 2.28E-23 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS03665 d0aa41437a2f8a4f4f6a1ff8bd14b96b 741 Gene3D G3DSA:3.30.420.10 448 477 2.1E-29 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS03665 d0aa41437a2f8a4f4f6a1ff8bd14b96b 741 Gene3D G3DSA:3.30.420.10 286 415 2.1E-29 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS04950 55c1e8008fd0e3c32ca7c7cafb2d6d8f 96 PANTHER PTHR13420 11 86 2.1E-25 T 22-04-2016 TOLA_RS04950 55c1e8008fd0e3c32ca7c7cafb2d6d8f 96 Gene3D G3DSA:3.30.1200.10 5 91 5.6E-32 T 22-04-2016 IPR003746 Protein of unknown function DUF167 TOLA_RS04950 55c1e8008fd0e3c32ca7c7cafb2d6d8f 96 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 5 88 2.0E-27 T 22-04-2016 IPR005228 Conserved hypothetical protein CHP00251 TOLA_RS04950 55c1e8008fd0e3c32ca7c7cafb2d6d8f 96 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 11 81 7.2E-28 T 22-04-2016 IPR003746 Protein of unknown function DUF167 TOLA_RS04950 55c1e8008fd0e3c32ca7c7cafb2d6d8f 96 SUPERFAMILY SSF69786 4 89 2.35E-32 T 22-04-2016 IPR003746 Protein of unknown function DUF167 TOLA_RS04950 55c1e8008fd0e3c32ca7c7cafb2d6d8f 96 Hamap MF_00634 UPF0235 protein YggU [yggU]. 7 95 20.668 T 22-04-2016 IPR003746 Protein of unknown function DUF167 TOLA_RS04950 55c1e8008fd0e3c32ca7c7cafb2d6d8f 96 SMART SM01152 7 83 5.7E-39 T 22-04-2016 IPR003746 Protein of unknown function DUF167 TOLA_RS06090 c2f50790dd1309881bc82154a0102a3c 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 1.9E-9 T 22-04-2016 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 TOLA_RS06090 c2f50790dd1309881bc82154a0102a3c 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 3.5E-7 T 22-04-2016 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 TOLA_RS07700 daeb3bb35012614905890417f0a61ef4 497 SUPERFAMILY SSF51905 1 276 8.42E-22 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS07700 daeb3bb35012614905890417f0a61ef4 497 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 6 495 7.7E-224 T 22-04-2016 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254|UniPathway: UPA00223 TOLA_RS07700 daeb3bb35012614905890417f0a61ef4 497 PANTHER PTHR13847:SF214 7 404 4.7E-160 T 22-04-2016 TOLA_RS07700 daeb3bb35012614905890417f0a61ef4 497 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 2 495 47.072 T 22-04-2016 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254|UniPathway: UPA00223 TOLA_RS07700 daeb3bb35012614905890417f0a61ef4 497 Gene3D G3DSA:3.50.50.60 5 97 1.8E-21 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS07700 daeb3bb35012614905890417f0a61ef4 497 Gene3D G3DSA:3.50.50.60 148 334 1.8E-21 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS07700 daeb3bb35012614905890417f0a61ef4 497 PANTHER PTHR13847 7 404 4.7E-160 T 22-04-2016 TOLA_RS07700 daeb3bb35012614905890417f0a61ef4 497 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 6 492 9.2E-198 T 22-04-2016 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254|UniPathway: UPA00223 TOLA_RS01605 90fd834ccca6d46d5bbe8fa6de9c974c 553 Pfam PF11426 Tn7 transposition regulator TnsC 506 552 2.3E-23 T 22-04-2016 IPR021542 Tn7 transposition regulator TnsC TOLA_RS01605 90fd834ccca6d46d5bbe8fa6de9c974c 553 Gene3D G3DSA:3.40.50.300 113 269 9.9E-10 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01605 90fd834ccca6d46d5bbe8fa6de9c974c 553 SMART SM00382 128 297 3.9E-7 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS01605 90fd834ccca6d46d5bbe8fa6de9c974c 553 SUPERFAMILY SSF52540 92 376 1.59E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS01605 90fd834ccca6d46d5bbe8fa6de9c974c 553 Pfam PF13401 AAA domain 127 275 1.1E-29 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS13645 54e32fda2fda59b8afdd431f5e89b3f2 513 Gene3D G3DSA:3.30.420.10 139 304 9.5E-10 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS13645 54e32fda2fda59b8afdd431f5e89b3f2 513 PANTHER PTHR35004:SF2 6 458 3.4E-104 T 22-04-2016 TOLA_RS13645 54e32fda2fda59b8afdd431f5e89b3f2 513 SUPERFAMILY SSF53098 141 303 1.26E-8 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS13645 54e32fda2fda59b8afdd431f5e89b3f2 513 Pfam PF00665 Integrase core domain 138 269 5.7E-19 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 TOLA_RS13645 54e32fda2fda59b8afdd431f5e89b3f2 513 PANTHER PTHR35004 6 458 3.4E-104 T 22-04-2016 TOLA_RS05480 29b1c65a114e9b74c0c6a3ab8ab8c047 124 Gene3D G3DSA:3.10.180.10 9 121 2.3E-16 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TOLA_RS05480 29b1c65a114e9b74c0c6a3ab8ab8c047 124 SUPERFAMILY SSF54593 11 123 6.85E-18 T 22-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TOLA_RS11475 a69fc5990b2fb569c9c08798629e9669 294 Gene3D G3DSA:2.60.200.30 150 263 1.4E-42 T 22-04-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 TOLA_RS11475 a69fc5990b2fb569c9c08798629e9669 294 Gene3D G3DSA:3.40.50.10330 4 149 2.3E-39 T 22-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 TOLA_RS11475 a69fc5990b2fb569c9c08798629e9669 294 PANTHER PTHR20275 5 290 8.2E-107 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 TOLA_RS11475 a69fc5990b2fb569c9c08798629e9669 294 Pfam PF01513 ATP-NAD kinase 61 271 2.9E-64 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 TOLA_RS11475 a69fc5990b2fb569c9c08798629e9669 294 SUPERFAMILY SSF111331 8 290 3.4E-92 T 22-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain TOLA_RS11475 a69fc5990b2fb569c9c08798629e9669 294 Hamap MF_00361 NAD kinase [nadK]. 6 289 33.778 T 22-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 TOLA_RS00265 70a02ab048c0d5d547285e23105516de 246 PANTHER PTHR26402:SF292 3 243 1.8E-72 T 22-04-2016 TOLA_RS00265 70a02ab048c0d5d547285e23105516de 246 Pfam PF00072 Response regulator receiver domain 5 112 9.7E-25 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS00265 70a02ab048c0d5d547285e23105516de 246 SMART SM00448 3 115 6.3E-35 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS00265 70a02ab048c0d5d547285e23105516de 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 236 1.3E-23 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS00265 70a02ab048c0d5d547285e23105516de 246 Gene3D G3DSA:3.40.50.2300 2 127 4.7E-37 T 22-04-2016 TOLA_RS00265 70a02ab048c0d5d547285e23105516de 246 SUPERFAMILY SSF46894 138 237 3.68E-25 T 22-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TOLA_RS00265 70a02ab048c0d5d547285e23105516de 246 Gene3D G3DSA:1.10.10.10 141 239 5.6E-28 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00265 70a02ab048c0d5d547285e23105516de 246 SUPERFAMILY SSF52172 2 130 7.68E-35 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS00265 70a02ab048c0d5d547285e23105516de 246 SMART SM00862 160 236 1.9E-22 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS00265 70a02ab048c0d5d547285e23105516de 246 PANTHER PTHR26402 3 243 1.8E-72 T 22-04-2016 TOLA_RS10270 b19fb84ac88fda34d88985d83981377e 168 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 134 6.0E-66 T 22-04-2016 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 TOLA_RS10270 b19fb84ac88fda34d88985d83981377e 168 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 22-04-2016 IPR030489 Transcription regulator Rrf2-type, conserved site TOLA_RS10270 b19fb84ac88fda34d88985d83981377e 168 PANTHER PTHR33221 2 152 4.0E-67 T 22-04-2016 TOLA_RS10270 b19fb84ac88fda34d88985d83981377e 168 Gene3D G3DSA:1.10.10.10 1 141 2.7E-32 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10270 b19fb84ac88fda34d88985d83981377e 168 PANTHER PTHR33221:SF1 2 152 4.0E-67 T 22-04-2016 TOLA_RS10270 b19fb84ac88fda34d88985d83981377e 168 Pfam PF02082 Transcriptional regulator 1 83 9.4E-27 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type TOLA_RS10270 b19fb84ac88fda34d88985d83981377e 168 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 7.9E-46 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type TOLA_RS10270 b19fb84ac88fda34d88985d83981377e 168 SUPERFAMILY SSF46785 2 133 6.96E-35 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06975 6d5b62ddb88edabac6b0a8c6f01b08b3 410 SUPERFAMILY SSF55021 338 409 1.29E-15 T 22-04-2016 TOLA_RS06975 6d5b62ddb88edabac6b0a8c6f01b08b3 410 SUPERFAMILY SSF52283 7 134 8.72E-50 T 22-04-2016 TOLA_RS06975 6d5b62ddb88edabac6b0a8c6f01b08b3 410 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 13 326 1.0E-37 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 TOLA_RS06975 6d5b62ddb88edabac6b0a8c6f01b08b3 410 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 22-04-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TOLA_RS06975 6d5b62ddb88edabac6b0a8c6f01b08b3 410 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 22-04-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TOLA_RS06975 6d5b62ddb88edabac6b0a8c6f01b08b3 410 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 294 1.4E-53 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TOLA_RS06975 6d5b62ddb88edabac6b0a8c6f01b08b3 410 PANTHER PTHR10996:SF18 1 370 5.7E-234 T 22-04-2016 IPR029015 D-3-phosphoglycerate dehydrogenase, type2 GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|UniPathway: UPA00135 TOLA_RS06975 6d5b62ddb88edabac6b0a8c6f01b08b3 410 PANTHER PTHR10996 1 370 5.7E-234 T 22-04-2016 TOLA_RS06975 6d5b62ddb88edabac6b0a8c6f01b08b3 410 Gene3D G3DSA:3.30.70.260 324 409 7.1E-27 T 22-04-2016 TOLA_RS06975 6d5b62ddb88edabac6b0a8c6f01b08b3 410 Gene3D G3DSA:3.40.50.720 120 297 9.4E-64 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS06975 6d5b62ddb88edabac6b0a8c6f01b08b3 410 Gene3D G3DSA:3.40.50.720 8 119 2.8E-36 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS06975 6d5b62ddb88edabac6b0a8c6f01b08b3 410 SUPERFAMILY SSF51735 108 295 2.15E-57 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS15145 8ecaadc6d400ab3fbb07b3d83140cbe3 163 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 100 115 2.78E-17 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 TOLA_RS15145 8ecaadc6d400ab3fbb07b3d83140cbe3 163 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 137 153 2.78E-17 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 TOLA_RS15145 8ecaadc6d400ab3fbb07b3d83140cbe3 163 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 52 60 2.78E-17 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 TOLA_RS15145 8ecaadc6d400ab3fbb07b3d83140cbe3 163 PANTHER PTHR33695:SF1 8 163 3.3E-53 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 TOLA_RS15145 8ecaadc6d400ab3fbb07b3d83140cbe3 163 TIGRFAM TIGR00077 lspA: signal peptidase II 6 160 1.8E-45 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 TOLA_RS15145 8ecaadc6d400ab3fbb07b3d83140cbe3 163 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 6 162 16.871 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 TOLA_RS15145 8ecaadc6d400ab3fbb07b3d83140cbe3 163 Pfam PF01252 Signal peptidase (SPase) II 15 156 3.9E-36 T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 TOLA_RS15145 8ecaadc6d400ab3fbb07b3d83140cbe3 163 ProSitePatterns PS00855 Signal peptidases II signature. 103 115 - T 22-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 TOLA_RS15145 8ecaadc6d400ab3fbb07b3d83140cbe3 163 PANTHER PTHR33695 8 163 3.3E-53 T 22-04-2016 TOLA_RS07850 fac3deeec52e89d19d2780d69a100d94 334 SUPERFAMILY SSF51445 2 285 2.42E-90 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS07850 fac3deeec52e89d19d2780d69a100d94 334 PANTHER PTHR30480 4 292 2.1E-131 T 22-04-2016 TOLA_RS07850 fac3deeec52e89d19d2780d69a100d94 334 Gene3D G3DSA:3.20.20.300 3 283 7.1E-97 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS07850 fac3deeec52e89d19d2780d69a100d94 334 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 7 282 2.4E-88 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS07850 fac3deeec52e89d19d2780d69a100d94 334 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 3 330 50.607 T 22-04-2016 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|UniPathway: UPA00544 TOLA_RS07850 fac3deeec52e89d19d2780d69a100d94 334 PANTHER PTHR30480:SF7 4 292 2.1E-131 T 22-04-2016 TOLA_RS07850 fac3deeec52e89d19d2780d69a100d94 334 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 232 249 - T 22-04-2016 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 TOLA_RS06310 ad05a6c1319fb11a780915c51060b2ba 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 274 1.5E-15 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06310 ad05a6c1319fb11a780915c51060b2ba 281 SUPERFAMILY SSF161098 8 281 7.98E-67 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06310 ad05a6c1319fb11a780915c51060b2ba 281 PANTHER PTHR32243 3 281 2.0E-96 T 22-04-2016 TOLA_RS06310 ad05a6c1319fb11a780915c51060b2ba 281 PANTHER PTHR32243:SF18 3 281 2.0E-96 T 22-04-2016 TOLA_RS06310 ad05a6c1319fb11a780915c51060b2ba 281 Gene3D G3DSA:1.10.3720.10 4 268 7.4E-58 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08550 d42736c492a90a42e8ecf6cf2d8f16df 457 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 251 442 7.6E-41 T 22-04-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 TOLA_RS08550 d42736c492a90a42e8ecf6cf2d8f16df 457 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 1 443 44.281 T 22-04-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 TOLA_RS08550 d42736c492a90a42e8ecf6cf2d8f16df 457 Gene3D G3DSA:3.40.50.880 258 455 5.0E-26 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS08550 d42736c492a90a42e8ecf6cf2d8f16df 457 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 193 2.6E-29 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TOLA_RS08550 d42736c492a90a42e8ecf6cf2d8f16df 457 PANTHER PTHR21343:SF6 1 235 8.5E-182 T 22-04-2016 TOLA_RS08550 d42736c492a90a42e8ecf6cf2d8f16df 457 PANTHER PTHR21343:SF6 253 457 8.5E-182 T 22-04-2016 TOLA_RS08550 d42736c492a90a42e8ecf6cf2d8f16df 457 PANTHER PTHR21343 1 235 8.5E-182 T 22-04-2016 TOLA_RS08550 d42736c492a90a42e8ecf6cf2d8f16df 457 PANTHER PTHR21343 253 457 8.5E-182 T 22-04-2016 TOLA_RS08550 d42736c492a90a42e8ecf6cf2d8f16df 457 SUPERFAMILY SSF52317 250 451 1.64E-33 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS08550 d42736c492a90a42e8ecf6cf2d8f16df 457 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 5 445 5.8E-143 T 22-04-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 TOLA_RS08550 d42736c492a90a42e8ecf6cf2d8f16df 457 SUPERFAMILY SSF52540 1 197 2.32E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08550 d42736c492a90a42e8ecf6cf2d8f16df 457 Gene3D G3DSA:3.40.50.300 1 195 8.3E-31 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11900 2a4663bd32aebf581739062f1a3af986 279 Gene3D G3DSA:3.10.50.40 130 257 9.2E-24 T 22-04-2016 TOLA_RS11900 2a4663bd32aebf581739062f1a3af986 279 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 178 198 - T 22-04-2016 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site TOLA_RS11900 2a4663bd32aebf581739062f1a3af986 279 SUPERFAMILY SSF109998 14 156 3.34E-16 T 22-04-2016 IPR027304 Trigger factor/SurA domain TOLA_RS11900 2a4663bd32aebf581739062f1a3af986 279 Pfam PF00639 PPIC-type PPIASE domain 143 237 1.7E-14 T 22-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 TOLA_RS11900 2a4663bd32aebf581739062f1a3af986 279 SUPERFAMILY SSF54534 129 237 7.85E-21 T 22-04-2016 TOLA_RS11900 2a4663bd32aebf581739062f1a3af986 279 PANTHER PTHR10657:SF11 39 277 2.5E-30 T 22-04-2016 TOLA_RS11900 2a4663bd32aebf581739062f1a3af986 279 TIGRFAM TIGR02933 nifM_nitrog: nitrogen fixation protein NifM 7 274 2.7E-64 T 22-04-2016 IPR014282 Nitrogen fixation protein NifM TOLA_RS11900 2a4663bd32aebf581739062f1a3af986 279 PANTHER PTHR10657 39 277 2.5E-30 T 22-04-2016 TOLA_RS07930 2773f6f0f4a14d9c61160151b385b75f 94 Pfam PF06305 Protein of unknown function (DUF1049) 27 88 4.1E-13 T 22-04-2016 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 TOLA_RS07930 2773f6f0f4a14d9c61160151b385b75f 94 Gene3D G3DSA:1.20.1070.10 10 87 4.8E-4 T 22-04-2016 TOLA_RS07930 2773f6f0f4a14d9c61160151b385b75f 94 Hamap MF_01948 Lipopolysaccharide assembly protein A [lapA]. 4 93 15.729 T 22-04-2016 IPR032906 Lipopolysaccharide assembly protein A GO:0005886|GO:0008653 TOLA_RS07815 14e48655e8130c86ab867f0cb0cfb137 461 PANTHER PTHR11785:SF337 10 433 1.8E-133 T 22-04-2016 TOLA_RS07815 14e48655e8130c86ab867f0cb0cfb137 461 TIGRFAM TIGR00908 2A0305: ethanolamine permease 7 448 5.0E-191 T 22-04-2016 IPR004757 Ethanolamine permease TOLA_RS07815 14e48655e8130c86ab867f0cb0cfb137 461 PANTHER PTHR11785 10 433 1.8E-133 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 TOLA_RS07815 14e48655e8130c86ab867f0cb0cfb137 461 Pfam PF13520 Amino acid permease 17 421 8.2E-40 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 TOLA_RS07815 14e48655e8130c86ab867f0cb0cfb137 461 PIRSF PIRSF006060 1 459 5.8E-71 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 TOLA_RS03550 77eed912db5e7297b4ea65a3a55ade49 163 Gene3D G3DSA:1.10.720.30 17 74 3.9E-29 T 22-04-2016 IPR003034 SAP domain TOLA_RS03550 77eed912db5e7297b4ea65a3a55ade49 163 Pfam PF09905 Uncharacterized conserved protein (DUF2132) 8 70 9.7E-32 T 22-04-2016 IPR018668 DNA-binding protein VF530-like, bacteria GO:0003677 TOLA_RS11815 4f2e4d632f8f7489ced4305f0b44cfdf 151 PANTHER PTHR22769:SF14 5 139 4.9E-24 T 22-04-2016 TOLA_RS11815 4f2e4d632f8f7489ced4305f0b44cfdf 151 Pfam PF00293 NUDIX domain 8 121 1.1E-14 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TOLA_RS11815 4f2e4d632f8f7489ced4305f0b44cfdf 151 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TOLA_RS11815 4f2e4d632f8f7489ced4305f0b44cfdf 151 PRINTS PR00502 NUDIX hydrolase family signature 32 46 6.8E-5 T 22-04-2016 IPR020476 NUDIX hydrolase TOLA_RS11815 4f2e4d632f8f7489ced4305f0b44cfdf 151 PRINTS PR00502 NUDIX hydrolase family signature 46 61 6.8E-5 T 22-04-2016 IPR020476 NUDIX hydrolase TOLA_RS11815 4f2e4d632f8f7489ced4305f0b44cfdf 151 SUPERFAMILY SSF55811 2 142 2.71E-28 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS11815 4f2e4d632f8f7489ced4305f0b44cfdf 151 Gene3D G3DSA:3.90.79.10 2 148 2.0E-32 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS11815 4f2e4d632f8f7489ced4305f0b44cfdf 151 PANTHER PTHR22769 5 139 4.9E-24 T 22-04-2016 TOLA_RS09515 5662ae4d0cc8b93eb0fcd6dee10ac0b4 121 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 5 115 5.7E-39 T 22-04-2016 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS09515 5662ae4d0cc8b93eb0fcd6dee10ac0b4 121 PANTHER PTHR40398 2 119 4.5E-36 T 22-04-2016 TOLA_RS09515 5662ae4d0cc8b93eb0fcd6dee10ac0b4 121 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 6 118 5.0E-31 T 22-04-2016 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS09515 5662ae4d0cc8b93eb0fcd6dee10ac0b4 121 Gene3D G3DSA:2.40.33.40 1 119 1.1E-42 T 22-04-2016 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS09515 5662ae4d0cc8b93eb0fcd6dee10ac0b4 121 SUPERFAMILY SSF141530 3 118 8.63E-38 T 22-04-2016 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS05305 35849e0eb7397a48d9289d63e13a2733 483 SUPERFAMILY SSF56954 16 479 8.37E-91 T 22-04-2016 TOLA_RS05305 35849e0eb7397a48d9289d63e13a2733 483 Gene3D G3DSA:2.20.200.10 327 362 2.5E-22 T 22-04-2016 TOLA_RS05305 35849e0eb7397a48d9289d63e13a2733 483 Gene3D G3DSA:2.20.200.10 115 153 2.5E-22 T 22-04-2016 TOLA_RS05305 35849e0eb7397a48d9289d63e13a2733 483 PANTHER PTHR30203:SF6 1 479 2.3E-153 T 22-04-2016 TOLA_RS05305 35849e0eb7397a48d9289d63e13a2733 483 PANTHER PTHR30203 1 479 2.3E-153 T 22-04-2016 TOLA_RS05305 35849e0eb7397a48d9289d63e13a2733 483 Gene3D G3DSA:1.20.1600.10 154 326 1.7E-82 T 22-04-2016 TOLA_RS05305 35849e0eb7397a48d9289d63e13a2733 483 Gene3D G3DSA:1.20.1600.10 62 102 1.7E-82 T 22-04-2016 TOLA_RS05305 35849e0eb7397a48d9289d63e13a2733 483 Gene3D G3DSA:1.20.1600.10 364 477 1.7E-82 T 22-04-2016 TOLA_RS05305 35849e0eb7397a48d9289d63e13a2733 483 Pfam PF02321 Outer membrane efflux protein 76 266 6.5E-18 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS05305 35849e0eb7397a48d9289d63e13a2733 483 Pfam PF02321 Outer membrane efflux protein 299 461 1.7E-25 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS05305 35849e0eb7397a48d9289d63e13a2733 483 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 23 477 4.0E-146 T 22-04-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 TOLA_RS11625 70d77e2844828f5d6699463fea03dd7a 323 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 6 310 3.8E-75 T 22-04-2016 IPR004481 Sodium/potassium/calcium exchanger Reactome: REACT_15518 TOLA_RS11625 70d77e2844828f5d6699463fea03dd7a 323 Pfam PF01699 Sodium/calcium exchanger protein 5 141 2.0E-24 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 TOLA_RS11625 70d77e2844828f5d6699463fea03dd7a 323 Pfam PF01699 Sodium/calcium exchanger protein 177 317 9.6E-30 T 22-04-2016 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: REACT_15518 TOLA_RS11625 70d77e2844828f5d6699463fea03dd7a 323 PANTHER PTHR10846 19 318 2.3E-54 T 22-04-2016 IPR004481 Sodium/potassium/calcium exchanger Reactome: REACT_15518 TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 PANTHER PTHR23359 1 213 4.1E-107 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 SUPERFAMILY SSF52540 1 208 1.46E-45 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 PRINTS PR00094 Adenylate kinase signature 32 46 7.2E-36 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 PRINTS PR00094 Adenylate kinase signature 4 17 7.2E-36 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 PRINTS PR00094 Adenylate kinase signature 81 97 7.2E-36 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 PRINTS PR00094 Adenylate kinase signature 156 171 7.2E-36 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 PRINTS PR00094 Adenylate kinase signature 173 187 7.2E-36 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 TIGRFAM TIGR01351 adk: adenylate kinase 2 210 1.4E-74 T 22-04-2016 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 Pfam PF00406 Adenylate kinase 5 186 1.9E-58 T 22-04-2016 TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 Hamap MF_00235 Adenylate kinase [adk]. 1 214 51.195 T 22-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 Gene3D G3DSA:3.40.50.300 1 209 3.4E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11235 aa456b4d6f36bedab0b19d0e8e2bdc1f 214 Pfam PF05191 Adenylate kinase, active site lid 123 158 4.4E-14 T 22-04-2016 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 TOLA_RS07655 1b86cf2b868c44881dd6c8f6e3581bc4 109 SUPERFAMILY SSF54909 10 101 9.08E-20 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel TOLA_RS07655 1b86cf2b868c44881dd6c8f6e3581bc4 109 PANTHER PTHR33336 10 93 2.7E-13 T 22-04-2016 TOLA_RS07655 1b86cf2b868c44881dd6c8f6e3581bc4 109 Pfam PF03992 Antibiotic biosynthesis monooxygenase 13 83 1.3E-9 T 22-04-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain TOLA_RS07655 1b86cf2b868c44881dd6c8f6e3581bc4 109 Gene3D G3DSA:3.30.70.900 9 101 1.7E-21 T 22-04-2016 TOLA_RS09595 7d4ea6713ca5bb0d33aa8c5f19550972 329 Gene3D G3DSA:3.40.50.720 1 142 9.0E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09595 7d4ea6713ca5bb0d33aa8c5f19550972 329 SUPERFAMILY SSF51735 2 152 3.56E-43 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09595 7d4ea6713ca5bb0d33aa8c5f19550972 329 PANTHER PTHR22604 1 319 1.5E-105 T 22-04-2016 TOLA_RS09595 7d4ea6713ca5bb0d33aa8c5f19550972 329 PANTHER PTHR22604:SF76 1 319 1.5E-105 T 22-04-2016 TOLA_RS09595 7d4ea6713ca5bb0d33aa8c5f19550972 329 Gene3D G3DSA:3.30.360.10 143 327 3.9E-65 T 22-04-2016 TOLA_RS09595 7d4ea6713ca5bb0d33aa8c5f19550972 329 SUPERFAMILY SSF55347 135 291 3.27E-27 T 22-04-2016 TOLA_RS09595 7d4ea6713ca5bb0d33aa8c5f19550972 329 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 119 4.2E-25 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 TOLA_RS00205 da9cff40d1dcfc5180f8330e228a4d54 410 SUPERFAMILY SSF56935 25 410 5.95E-142 T 22-04-2016 TOLA_RS00205 da9cff40d1dcfc5180f8330e228a4d54 410 ProDom PD008788 PORIN MEMBRANE PRECURSOR SIGNAL MALTOPORIN OUTER ION TRANSMEMBRANE RECEPTOR LAMB 31 405 8.0E-158 T 22-04-2016 IPR003192 Porin, LamB type GO:0006810|GO:0016020 TOLA_RS00205 da9cff40d1dcfc5180f8330e228a4d54 410 Pfam PF02264 LamB porin 27 410 4.7E-142 T 22-04-2016 IPR003192 Porin, LamB type GO:0006810|GO:0016020 TOLA_RS00205 da9cff40d1dcfc5180f8330e228a4d54 410 Gene3D G3DSA:2.40.170.10 25 410 2.4E-157 T 22-04-2016 IPR003192 Porin, LamB type GO:0006810|GO:0016020 TOLA_RS00205 da9cff40d1dcfc5180f8330e228a4d54 410 PANTHER PTHR38762 1 410 4.1E-175 T 22-04-2016 TOLA_RS13440 a137405a9a734947f08ca5f316cbb2a7 223 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 45 181 7.5E-67 T 22-04-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 TOLA_RS13440 a137405a9a734947f08ca5f316cbb2a7 223 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 147 163 - T 22-04-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 TOLA_RS13440 a137405a9a734947f08ca5f316cbb2a7 223 Gene3D G3DSA:3.40.50.700 50 178 1.1E-29 T 22-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 TOLA_RS13440 a137405a9a734947f08ca5f316cbb2a7 223 PANTHER PTHR11995:SF14 2 219 1.4E-127 T 22-04-2016 TOLA_RS13440 a137405a9a734947f08ca5f316cbb2a7 223 PANTHER PTHR11995 2 219 1.4E-127 T 22-04-2016 TOLA_RS13440 a137405a9a734947f08ca5f316cbb2a7 223 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 67 173 2.0E-20 T 22-04-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 TOLA_RS13440 a137405a9a734947f08ca5f316cbb2a7 223 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 23 180 41.824 T 22-04-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 TOLA_RS13440 a137405a9a734947f08ca5f316cbb2a7 223 SUPERFAMILY SSF56770 42 188 5.76E-62 T 22-04-2016 TOLA_RS02955 1d329d1466dc0227a7b6773ba4013242 500 Gene3D G3DSA:3.40.50.300 268 485 2.4E-52 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02955 1d329d1466dc0227a7b6773ba4013242 500 Gene3D G3DSA:3.40.50.300 2 233 4.2E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02955 1d329d1466dc0227a7b6773ba4013242 500 Pfam PF00005 ABC transporter 21 169 2.5E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS02955 1d329d1466dc0227a7b6773ba4013242 500 Pfam PF00005 ABC transporter 269 422 3.9E-23 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS02955 1d329d1466dc0227a7b6773ba4013242 500 SMART SM00382 277 471 1.4E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS02955 1d329d1466dc0227a7b6773ba4013242 500 SMART SM00382 29 248 8.8E-9 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS02955 1d329d1466dc0227a7b6773ba4013242 500 SUPERFAMILY SSF52540 268 482 1.74E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02955 1d329d1466dc0227a7b6773ba4013242 500 SUPERFAMILY SSF52540 3 229 7.39E-57 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02955 1d329d1466dc0227a7b6773ba4013242 500 ProSitePatterns PS00211 ABC transporters family signature. 395 409 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS02955 1d329d1466dc0227a7b6773ba4013242 500 PANTHER PTHR24220 6 377 9.9E-202 T 22-04-2016 TOLA_RS02955 1d329d1466dc0227a7b6773ba4013242 500 PANTHER PTHR24220:SF416 6 377 9.9E-202 T 22-04-2016 TOLA_RS06040 e96f9d4160126f07ff3b202491fee7c4 445 Pfam PF01420 Type I restriction modification DNA specificity domain 243 415 1.6E-17 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TOLA_RS06040 e96f9d4160126f07ff3b202491fee7c4 445 Pfam PF01420 Type I restriction modification DNA specificity domain 21 205 2.8E-13 T 22-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TOLA_RS06040 e96f9d4160126f07ff3b202491fee7c4 445 PANTHER PTHR30408 232 435 1.6E-24 T 22-04-2016 TOLA_RS06040 e96f9d4160126f07ff3b202491fee7c4 445 PANTHER PTHR30408:SF2 232 435 1.6E-24 T 22-04-2016 TOLA_RS06040 e96f9d4160126f07ff3b202491fee7c4 445 SUPERFAMILY SSF116734 7 222 4.41E-44 T 22-04-2016 TOLA_RS06040 e96f9d4160126f07ff3b202491fee7c4 445 SUPERFAMILY SSF116734 230 436 2.62E-41 T 22-04-2016 TOLA_RS04070 320144cf34658af47d2b7c6ce060882e 160 SUPERFAMILY SSF89963 88 160 7.32E-29 T 22-04-2016 IPR007551 Protein of unknown function DUF520 TOLA_RS04070 320144cf34658af47d2b7c6ce060882e 160 PANTHER PTHR30476 1 160 1.2E-91 T 22-04-2016 TOLA_RS04070 320144cf34658af47d2b7c6ce060882e 160 Gene3D G3DSA:3.30.70.990 9 94 3.2E-34 T 22-04-2016 TOLA_RS04070 320144cf34658af47d2b7c6ce060882e 160 Gene3D G3DSA:3.30.70.860 95 160 1.8E-33 T 22-04-2016 TOLA_RS04070 320144cf34658af47d2b7c6ce060882e 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 29.52 T 22-04-2016 IPR007551 Protein of unknown function DUF520 TOLA_RS04070 320144cf34658af47d2b7c6ce060882e 160 SUPERFAMILY SSF89963 2 86 1.03E-31 T 22-04-2016 IPR007551 Protein of unknown function DUF520 TOLA_RS04070 320144cf34658af47d2b7c6ce060882e 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 1.2E-64 T 22-04-2016 IPR007551 Protein of unknown function DUF520 TOLA_RS04070 320144cf34658af47d2b7c6ce060882e 160 PANTHER PTHR30476:SF0 1 160 1.2E-91 T 22-04-2016 TOLA_RS05820 5062641d153af4078457ac7e5b5714a1 89 Gene3D G3DSA:1.10.260.40 11 74 9.3E-13 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS05820 5062641d153af4078457ac7e5b5714a1 89 Pfam PF01381 Helix-turn-helix 12 57 2.8E-7 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS05820 5062641d153af4078457ac7e5b5714a1 89 SMART SM00530 11 68 2.6E-5 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS05820 5062641d153af4078457ac7e5b5714a1 89 SUPERFAMILY SSF47413 6 62 2.15E-10 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS00230 a6edcb550146f0574295b6a7f0c3ca6d 86 Gene3D G3DSA:3.40.1620.10 1 48 9.7E-11 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TOLA_RS00230 a6edcb550146f0574295b6a7f0c3ca6d 86 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 60 2.1E-11 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TOLA_RS00230 a6edcb550146f0574295b6a7f0c3ca6d 86 SUPERFAMILY SSF143120 1 75 3.4E-15 T 22-04-2016 TOLA_RS00230 a6edcb550146f0574295b6a7f0c3ca6d 86 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 63 5.0E-15 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TOLA_RS06535 cb624b95f493db5de7a9a71ab93418df 574 PANTHER PTHR24221 466 571 1.5E-169 T 22-04-2016 TOLA_RS06535 cb624b95f493db5de7a9a71ab93418df 574 PANTHER PTHR24221 2 445 1.5E-169 T 22-04-2016 TOLA_RS06535 cb624b95f493db5de7a9a71ab93418df 574 Gene3D G3DSA:1.20.1560.10 7 321 4.9E-68 T 22-04-2016 TOLA_RS06535 cb624b95f493db5de7a9a71ab93418df 574 SMART SM00382 360 539 6.9E-10 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS06535 cb624b95f493db5de7a9a71ab93418df 574 SUPERFAMILY SSF52540 324 570 2.15E-79 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06535 cb624b95f493db5de7a9a71ab93418df 574 Gene3D G3DSA:3.40.50.300 334 564 2.6E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06535 cb624b95f493db5de7a9a71ab93418df 574 Pfam PF00005 ABC transporter 351 499 9.4E-35 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS06535 cb624b95f493db5de7a9a71ab93418df 574 SUPERFAMILY SSF90123 7 322 4.05E-65 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS06535 cb624b95f493db5de7a9a71ab93418df 574 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS06535 cb624b95f493db5de7a9a71ab93418df 574 Pfam PF00664 ABC transporter transmembrane region 21 291 1.3E-34 T 22-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TOLA_RS13990 520e29cb080e2eb305c3e1510a18eec9 248 PANTHER PTHR30457 1 243 2.8E-93 T 22-04-2016 TOLA_RS13990 520e29cb080e2eb305c3e1510a18eec9 248 Pfam PF01975 Survival protein SurE 3 181 4.3E-58 T 22-04-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 TOLA_RS13990 520e29cb080e2eb305c3e1510a18eec9 248 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 232 4.1E-73 T 22-04-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 TOLA_RS13990 520e29cb080e2eb305c3e1510a18eec9 248 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 247 40.265 T 22-04-2016 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 TOLA_RS13990 520e29cb080e2eb305c3e1510a18eec9 248 SUPERFAMILY SSF64167 1 244 1.26E-84 T 22-04-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 TOLA_RS13990 520e29cb080e2eb305c3e1510a18eec9 248 Gene3D G3DSA:3.40.1210.10 1 244 2.5E-88 T 22-04-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 PIRSF PIRSF000106 36 476 4.3E-90 T 22-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 SUPERFAMILY SSF53223 88 236 1.73E-57 T 22-04-2016 TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 SMART SM00919 238 460 6.7E-111 T 22-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 Pfam PF03949 Malic enzyme, NAD binding domain 240 459 6.7E-24 T 22-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 SUPERFAMILY SSF51735 238 470 1.97E-72 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 PRINTS PR00072 Malic enzyme signature 234 250 2.6E-7 T 22-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 PRINTS PR00072 Malic enzyme signature 155 177 2.6E-7 T 22-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 PRINTS PR00072 Malic enzyme signature 265 281 2.6E-7 T 22-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 PANTHER PTHR23406 10 468 6.5E-178 T 22-04-2016 TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 PANTHER PTHR23406:SF23 10 468 6.5E-178 T 22-04-2016 TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 Gene3D G3DSA:3.40.50.10380 92 235 5.4E-56 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 Gene3D G3DSA:3.40.50.720 236 471 8.1E-76 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 Pfam PF00390 Malic enzyme, N-terminal domain 95 226 1.0E-30 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TOLA_RS01140 f3f04f1467abf01f62e8e71d3dd12e93 477 SMART SM01274 93 226 1.1E-84 T 22-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 Gene3D G3DSA:3.40.50.1700 495 663 3.8E-50 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 Gene3D G3DSA:3.40.50.1700 385 460 3.8E-50 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 103 364 2.9E-48 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 PANTHER PTHR30620:SF18 479 787 1.1E-215 T 22-04-2016 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 PANTHER PTHR30620:SF18 2 454 1.1E-215 T 22-04-2016 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 398 664 2.5E-39 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 Pfam PF14310 Fibronectin type III-like domain 701 772 1.4E-21 T 22-04-2016 IPR026891 Fibronectin type III-like domain TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 Gene3D G3DSA:3.20.20.300 37 374 2.3E-89 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 PRINTS PR00133 Glycosyl hydrolase family 3 signature 103 119 6.9E-29 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 PRINTS PR00133 Glycosyl hydrolase family 3 signature 283 301 6.9E-29 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 PRINTS PR00133 Glycosyl hydrolase family 3 signature 213 229 6.9E-29 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 PRINTS PR00133 Glycosyl hydrolase family 3 signature 136 155 6.9E-29 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 PRINTS PR00133 Glycosyl hydrolase family 3 signature 182 198 6.9E-29 T 22-04-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 SUPERFAMILY SSF52279 645 667 3.4E-40 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 SUPERFAMILY SSF52279 498 615 3.4E-40 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 SUPERFAMILY SSF52279 398 468 3.4E-40 T 22-04-2016 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 PANTHER PTHR30620 479 787 1.1E-215 T 22-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 PANTHER PTHR30620 2 454 1.1E-215 T 22-04-2016 IPR026892 Glycoside hydrolase family 3 GO:0004553 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 SUPERFAMILY SSF51445 38 397 9.79E-81 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 283 300 - T 22-04-2016 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 TOLA_RS07720 f23358b76ff43d28f498a5ceef9d8063 814 SMART SM01217 701 772 2.1E-25 T 22-04-2016 IPR026891 Fibronectin type III-like domain TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 Gene3D G3DSA:3.30.450.20 137 262 1.6E-15 T 22-04-2016 TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 Pfam PF08448 PAS fold 144 251 2.1E-10 T 22-04-2016 IPR013656 PAS fold-4 TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 258 421 1.2E-47 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 PANTHER PTHR10799 237 420 2.7E-27 T 22-04-2016 TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 Pfam PF00990 Diguanylate cyclase, GGDEF domain 261 417 4.9E-43 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 SUPERFAMILY SSF55785 121 242 9.6E-12 T 22-04-2016 IPR000014 PAS domain TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 Pfam PF12860 PAS fold 22 130 1.1E-7 T 22-04-2016 TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 SMART SM00267 250 421 6.1E-58 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 SUPERFAMILY SSF55073 266 421 4.63E-47 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 137 257 1.9E-8 T 22-04-2016 IPR000014 PAS domain TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 SMART SM00091 137 203 0.0013 T 22-04-2016 IPR000014 PAS domain TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 Gene3D G3DSA:3.30.70.270 263 422 1.6E-51 T 22-04-2016 TOLA_RS16340 5d82a36266a0256d76ea0a5a04d2dbf1 423 PANTHER PTHR10799:SF750 237 420 2.7E-27 T 22-04-2016 TOLA_RS03220 c93ee522fe06452c2a7a3d52187c142d 424 SUPERFAMILY SSF53686 1 423 1.96E-127 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TOLA_RS03220 c93ee522fe06452c2a7a3d52187c142d 424 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 92 366 4.5E-23 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TOLA_RS03220 c93ee522fe06452c2a7a3d52187c142d 424 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 95 109 - T 22-04-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TOLA_RS03220 c93ee522fe06452c2a7a3d52187c142d 424 PANTHER PTHR10314 25 424 4.9E-132 T 22-04-2016 TOLA_RS03220 c93ee522fe06452c2a7a3d52187c142d 424 Pfam PF14821 Threonine synthase N terminus 7 78 8.3E-7 T 22-04-2016 IPR029144 Threonine synthase, N-terminal TOLA_RS03220 c93ee522fe06452c2a7a3d52187c142d 424 Gene3D G3DSA:3.90.1380.10 1 82 4.5E-15 T 22-04-2016 IPR029144 Threonine synthase, N-terminal TOLA_RS03220 c93ee522fe06452c2a7a3d52187c142d 424 TIGRFAM TIGR00260 thrC: threonine synthase 58 393 3.7E-113 T 22-04-2016 IPR004450 Threonine synthase-like TOLA_RS03220 c93ee522fe06452c2a7a3d52187c142d 424 Gene3D G3DSA:3.40.50.1100 104 193 6.9E-13 T 22-04-2016 TOLA_RS03220 c93ee522fe06452c2a7a3d52187c142d 424 Gene3D G3DSA:3.40.50.1100 325 399 1.4E-12 T 22-04-2016 TOLA_RS03220 c93ee522fe06452c2a7a3d52187c142d 424 Gene3D G3DSA:3.40.50.1100 194 316 8.7E-52 T 22-04-2016 TOLA_RS03220 c93ee522fe06452c2a7a3d52187c142d 424 PANTHER PTHR10314:SF1 25 424 4.9E-132 T 22-04-2016 TOLA_RS14840 e7222150c0e5a59dcf657c3eca316771 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.5E-9 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS14840 e7222150c0e5a59dcf657c3eca316771 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.5E-9 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS14840 e7222150c0e5a59dcf657c3eca316771 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.5E-9 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS14840 e7222150c0e5a59dcf657c3eca316771 308 SUPERFAMILY SSF46785 1 82 9.85E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14840 e7222150c0e5a59dcf657c3eca316771 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.5E-23 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS14840 e7222150c0e5a59dcf657c3eca316771 308 Gene3D G3DSA:1.10.10.10 1 83 1.6E-29 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14840 e7222150c0e5a59dcf657c3eca316771 308 Gene3D G3DSA:3.40.190.10 88 174 9.9E-23 T 22-04-2016 TOLA_RS14840 e7222150c0e5a59dcf657c3eca316771 308 Gene3D G3DSA:3.40.190.10 175 262 3.1E-21 T 22-04-2016 TOLA_RS14840 e7222150c0e5a59dcf657c3eca316771 308 PANTHER PTHR30346 1 308 6.0E-82 T 22-04-2016 TOLA_RS14840 e7222150c0e5a59dcf657c3eca316771 308 SUPERFAMILY SSF53850 91 295 1.21E-29 T 22-04-2016 TOLA_RS14840 e7222150c0e5a59dcf657c3eca316771 308 Pfam PF03466 LysR substrate binding domain 89 291 5.0E-30 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS02805 83c5f506695135539958f7cf4d90c0ea 83 PANTHER PTHR33713 1 72 2.0E-28 T 22-04-2016 TOLA_RS02805 83c5f506695135539958f7cf4d90c0ea 83 PANTHER PTHR33713:SF1 1 72 2.0E-28 T 22-04-2016 TOLA_RS08620 4b125ab7d5043a89b24d3fc891fa9c87 95 PANTHER PTHR36539 1 91 2.6E-36 T 22-04-2016 TOLA_RS08620 4b125ab7d5043a89b24d3fc891fa9c87 95 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 11 87 4.0E-18 T 22-04-2016 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml TOLA_RS08620 4b125ab7d5043a89b24d3fc891fa9c87 95 Gene3D G3DSA:2.40.50.220 1 91 1.8E-33 T 22-04-2016 IPR023414 Ethanolamine utilization protein-like domain TOLA_RS08620 4b125ab7d5043a89b24d3fc891fa9c87 95 SUPERFAMILY SSF159133 1 91 4.97E-27 T 22-04-2016 IPR023414 Ethanolamine utilization protein-like domain TOLA_RS08620 4b125ab7d5043a89b24d3fc891fa9c87 95 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 87 2.3E-32 T 22-04-2016 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml TOLA_RS08620 4b125ab7d5043a89b24d3fc891fa9c87 95 PANTHER PTHR36539:SF1 1 91 2.6E-36 T 22-04-2016 TOLA_RS09460 a412ffbd47461a673cb07c2c2c2d555e 222 SMART SM00895 86 209 2.3E-7 T 22-04-2016 IPR011711 GntR, C-terminal TOLA_RS09460 a412ffbd47461a673cb07c2c2c2d555e 222 Gene3D G3DSA:1.10.10.10 5 77 1.5E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09460 a412ffbd47461a673cb07c2c2c2d555e 222 SUPERFAMILY SSF46785 9 80 1.76E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09460 a412ffbd47461a673cb07c2c2c2d555e 222 SMART SM00345 18 76 1.4E-12 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS09460 a412ffbd47461a673cb07c2c2c2d555e 222 Gene3D G3DSA:1.20.120.530 81 219 3.9E-31 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal TOLA_RS09460 a412ffbd47461a673cb07c2c2c2d555e 222 PANTHER PTHR11751:SF436 12 102 4.1E-22 T 22-04-2016 TOLA_RS09460 a412ffbd47461a673cb07c2c2c2d555e 222 Pfam PF07729 FCD domain 86 208 4.2E-14 T 22-04-2016 IPR011711 GntR, C-terminal TOLA_RS09460 a412ffbd47461a673cb07c2c2c2d555e 222 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 76 6.2E-16 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS09460 a412ffbd47461a673cb07c2c2c2d555e 222 PANTHER PTHR11751 12 102 4.1E-22 T 22-04-2016 TOLA_RS09460 a412ffbd47461a673cb07c2c2c2d555e 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 9.4E-6 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS09460 a412ffbd47461a673cb07c2c2c2d555e 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 9.4E-6 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS09460 a412ffbd47461a673cb07c2c2c2d555e 222 SUPERFAMILY SSF48008 82 217 3.92E-23 T 22-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal TOLA_RS06665 7431d6779f507d3f09a4a0c5253a028a 98 Gene3D G3DSA:1.20.5.780 12 93 6.9E-22 T 22-04-2016 TOLA_RS06665 7431d6779f507d3f09a4a0c5253a028a 98 PANTHER PTHR35401 16 98 2.1E-25 T 22-04-2016 TOLA_RS06665 7431d6779f507d3f09a4a0c5253a028a 98 PANTHER PTHR35401:SF1 16 98 2.1E-25 T 22-04-2016 TOLA_RS06665 7431d6779f507d3f09a4a0c5253a028a 98 Pfam PF08681 Protein of unknown function (DUF1778) 16 92 1.6E-25 T 22-04-2016 IPR014795 Vibrio phage ICP1, Orf50 TOLA_RS06665 7431d6779f507d3f09a4a0c5253a028a 98 SUPERFAMILY SSF47598 13 90 3.11E-21 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 TOLA_RS06565 e774d0803e0146e57f1ef4ce6696425c 109 Gene3D G3DSA:3.40.30.10 16 105 2.2E-15 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS06565 e774d0803e0146e57f1ef4ce6696425c 109 PANTHER PTHR10438 21 104 8.8E-12 T 22-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TOLA_RS06565 e774d0803e0146e57f1ef4ce6696425c 109 SUPERFAMILY SSF52833 14 104 3.15E-20 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS06565 e774d0803e0146e57f1ef4ce6696425c 109 Pfam PF00085 Thioredoxin 15 103 5.3E-12 T 22-04-2016 IPR013766 Thioredoxin domain GO:0045454 TOLA_RS08700 9de39923202aa33aad1ec6af66c89e23 293 PANTHER PTHR30193 1 291 6.2E-85 T 22-04-2016 TOLA_RS08700 9de39923202aa33aad1ec6af66c89e23 293 SUPERFAMILY SSF161098 54 278 7.46E-56 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08700 9de39923202aa33aad1ec6af66c89e23 293 PANTHER PTHR30193:SF6 1 291 6.2E-85 T 22-04-2016 TOLA_RS08700 9de39923202aa33aad1ec6af66c89e23 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 286 8.9E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08700 9de39923202aa33aad1ec6af66c89e23 293 Gene3D G3DSA:1.10.3720.10 60 288 8.3E-57 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS04735 d27ddac4db78740ed1fae255c1519b77 232 SUPERFAMILY SSF56214 8 88 6.41E-17 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 TOLA_RS04735 d27ddac4db78740ed1fae255c1519b77 232 Gene3D G3DSA:3.90.470.20 13 108 5.5E-25 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 TOLA_RS04735 d27ddac4db78740ed1fae255c1519b77 232 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 95 183 1.6E-14 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 TOLA_RS04735 d27ddac4db78740ed1fae255c1519b77 232 PANTHER PTHR12215 1 176 2.4E-35 T 22-04-2016 TOLA_RS04735 d27ddac4db78740ed1fae255c1519b77 232 SUPERFAMILY SSF56214 95 169 1.17E-20 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 TOLA_RS04735 d27ddac4db78740ed1fae255c1519b77 232 PANTHER PTHR12215:SF10 1 176 2.4E-35 T 22-04-2016 TOLA_RS04735 d27ddac4db78740ed1fae255c1519b77 232 Gene3D G3DSA:3.90.470.20 109 168 3.1E-18 T 22-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 TOLA_RS11670 d0facdf43bc29925d4b9b1390e8a369e 508 Pfam PF01743 Poly A polymerase head domain 90 219 3.6E-37 T 22-04-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 TOLA_RS11670 d0facdf43bc29925d4b9b1390e8a369e 508 PANTHER PTHR13734 57 350 1.8E-127 T 22-04-2016 TOLA_RS11670 d0facdf43bc29925d4b9b1390e8a369e 508 Gene3D G3DSA:3.30.460.10 60 216 3.7E-49 T 22-04-2016 TOLA_RS11670 d0facdf43bc29925d4b9b1390e8a369e 508 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 247 308 1.6E-19 T 22-04-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain TOLA_RS11670 d0facdf43bc29925d4b9b1390e8a369e 508 SUPERFAMILY SSF81301 60 216 2.83E-40 T 22-04-2016 TOLA_RS11670 d0facdf43bc29925d4b9b1390e8a369e 508 PANTHER PTHR13734:SF47 57 350 1.8E-127 T 22-04-2016 TOLA_RS11670 d0facdf43bc29925d4b9b1390e8a369e 508 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 52 501 37.818 T 22-04-2016 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 TOLA_RS11670 d0facdf43bc29925d4b9b1390e8a369e 508 Gene3D G3DSA:1.10.3090.10 217 455 1.9E-44 T 22-04-2016 TOLA_RS11670 d0facdf43bc29925d4b9b1390e8a369e 508 SUPERFAMILY SSF81891 219 455 3.14E-44 T 22-04-2016 TOLA_RS11670 d0facdf43bc29925d4b9b1390e8a369e 508 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 58 491 8.6E-154 T 22-04-2016 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 TOLA_RS11670 d0facdf43bc29925d4b9b1390e8a369e 508 Pfam PF12626 Polymerase A arginine-rich C-terminus 365 496 1.4E-33 T 22-04-2016 IPR025866 Polymerase A arginine-rich C-terminal domain TOLA_RS01160 fe5096b381bcc0940305691d95aa4ba4 266 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 261 1.9E-104 T 22-04-2016 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TOLA_RS01160 fe5096b381bcc0940305691d95aa4ba4 266 PANTHER PTHR20858 2 265 2.7E-123 T 22-04-2016 TOLA_RS01160 fe5096b381bcc0940305691d95aa4ba4 266 Gene3D G3DSA:3.40.1190.20 3 261 4.6E-105 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS01160 fe5096b381bcc0940305691d95aa4ba4 266 SUPERFAMILY SSF53613 1 265 5.77E-84 T 22-04-2016 IPR029056 Ribokinase-like TOLA_RS01160 fe5096b381bcc0940305691d95aa4ba4 266 Pfam PF08543 Phosphomethylpyrimidine kinase 12 259 6.0E-98 T 22-04-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 TOLA_RS01160 fe5096b381bcc0940305691d95aa4ba4 266 PANTHER PTHR20858:SF17 2 265 2.7E-123 T 22-04-2016 TOLA_RS07380 8b8f39fdc3806cfd25b3268d895329fc 348 PANTHER PTHR30578 1 348 6.6E-122 T 22-04-2016 TOLA_RS07380 8b8f39fdc3806cfd25b3268d895329fc 348 Pfam PF03116 NQR2, RnfD, RnfE family 6 347 1.0E-95 T 22-04-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 TOLA_RS07380 8b8f39fdc3806cfd25b3268d895329fc 348 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 3 348 25.981 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 TOLA_RS07380 8b8f39fdc3806cfd25b3268d895329fc 348 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 8 348 3.7E-125 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 TOLA_RS07380 8b8f39fdc3806cfd25b3268d895329fc 348 PANTHER PTHR30578:SF0 1 348 6.6E-122 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 TOLA_RS16125 c00be36f3d593bac744f189963fc5fe0 209 Gene3D G3DSA:3.40.50.150 7 207 1.8E-69 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS16125 c00be36f3d593bac744f189963fc5fe0 209 PIRSF PIRSF003078 1 208 4.9E-65 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TOLA_RS16125 c00be36f3d593bac744f189963fc5fe0 209 Pfam PF02527 rRNA small subunit methyltransferase G 23 202 2.8E-59 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TOLA_RS16125 c00be36f3d593bac744f189963fc5fe0 209 PANTHER PTHR31760 7 207 3.5E-82 T 22-04-2016 TOLA_RS16125 c00be36f3d593bac744f189963fc5fe0 209 SUPERFAMILY SSF53335 7 207 1.32E-41 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS16125 c00be36f3d593bac744f189963fc5fe0 209 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 16 204 28.276 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TOLA_RS16125 c00be36f3d593bac744f189963fc5fe0 209 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 29 207 6.1E-57 T 22-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TOLA_RS16125 c00be36f3d593bac744f189963fc5fe0 209 PANTHER PTHR31760:SF0 7 207 3.5E-82 T 22-04-2016 TOLA_RS07555 6a61b74a9d8fa90bd73fa64bfb00399b 477 Pfam PF00232 Glycosyl hydrolase family 1 2 474 5.1E-136 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS07555 6a61b74a9d8fa90bd73fa64bfb00399b 477 PANTHER PTHR10353:SF35 4 477 2.4E-242 T 22-04-2016 TOLA_RS07555 6a61b74a9d8fa90bd73fa64bfb00399b 477 SUPERFAMILY SSF51445 1 475 6.55E-164 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS07555 6a61b74a9d8fa90bd73fa64bfb00399b 477 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 22-04-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TOLA_RS07555 6a61b74a9d8fa90bd73fa64bfb00399b 477 Gene3D G3DSA:3.20.20.80 4 475 2.8E-153 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS07555 6a61b74a9d8fa90bd73fa64bfb00399b 477 PANTHER PTHR10353 4 477 2.4E-242 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS07555 6a61b74a9d8fa90bd73fa64bfb00399b 477 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 371 379 - T 22-04-2016 IPR018120 Glycoside hydrolase family 1, active site TOLA_RS07555 6a61b74a9d8fa90bd73fa64bfb00399b 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 439 451 3.9E-17 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS07555 6a61b74a9d8fa90bd73fa64bfb00399b 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 371 379 3.9E-17 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS07555 6a61b74a9d8fa90bd73fa64bfb00399b 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 305 319 3.9E-17 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS07555 6a61b74a9d8fa90bd73fa64bfb00399b 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 414 431 3.9E-17 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS07555 6a61b74a9d8fa90bd73fa64bfb00399b 477 PRINTS PR00131 Glycosyl hydrolase family 1 signature 392 403 3.9E-17 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS06450 11bc6bb615486379eee7e57836caab9b 241 PANTHER PTHR39327 34 241 1.4E-74 T 22-04-2016 TOLA_RS06450 11bc6bb615486379eee7e57836caab9b 241 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 77 180 7.7E-11 T 22-04-2016 IPR010319 Transglutaminase-like cysteine peptidase, predicted TOLA_RS06450 11bc6bb615486379eee7e57836caab9b 241 PANTHER PTHR39327:SF1 34 241 1.4E-74 T 22-04-2016 TOLA_RS08570 ebea9376c36abd244d2ac7f1ba6970dd 268 PANTHER PTHR40609:SF2 37 268 3.0E-182 T 22-04-2016 TOLA_RS08570 ebea9376c36abd244d2ac7f1ba6970dd 268 PANTHER PTHR40609 37 268 3.0E-182 T 22-04-2016 TOLA_RS08570 ebea9376c36abd244d2ac7f1ba6970dd 268 TIGRFAM TIGR04501 microcomp_PduB: microcompartment protein PduB 44 268 1.2E-121 T 22-04-2016 IPR030984 Microcompartment protein PduB GO:0005198 TOLA_RS08570 ebea9376c36abd244d2ac7f1ba6970dd 268 Pfam PF00936 BMC domain 78 151 3.2E-12 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08570 ebea9376c36abd244d2ac7f1ba6970dd 268 Pfam PF00936 BMC domain 184 254 1.7E-14 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08570 ebea9376c36abd244d2ac7f1ba6970dd 268 SUPERFAMILY SSF143414 183 263 5.36E-12 T 22-04-2016 TOLA_RS08570 ebea9376c36abd244d2ac7f1ba6970dd 268 SUPERFAMILY SSF143414 77 155 2.09E-9 T 22-04-2016 TOLA_RS08570 ebea9376c36abd244d2ac7f1ba6970dd 268 SMART SM00877 77 159 6.4E-11 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08570 ebea9376c36abd244d2ac7f1ba6970dd 268 SMART SM00877 183 260 1.8E-15 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08570 ebea9376c36abd244d2ac7f1ba6970dd 268 PIRSF PIRSF012290 36 268 4.1E-105 T 22-04-2016 IPR009193 Polyhedral organelle shell protein, EutL/PduB type GO:0009605 TOLA_RS10215 58c01943be7719f80b3592b44bc986f0 307 Gene3D G3DSA:1.10.10.10 5 82 9.1E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10215 58c01943be7719f80b3592b44bc986f0 307 SUPERFAMILY SSF46785 4 80 1.82E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10215 58c01943be7719f80b3592b44bc986f0 307 SUPERFAMILY SSF53850 86 295 1.92E-25 T 22-04-2016 TOLA_RS10215 58c01943be7719f80b3592b44bc986f0 307 PANTHER PTHR30346 1 307 5.2E-41 T 22-04-2016 TOLA_RS10215 58c01943be7719f80b3592b44bc986f0 307 Pfam PF03466 LysR substrate binding domain 86 298 4.8E-19 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS10215 58c01943be7719f80b3592b44bc986f0 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 1.3E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10215 58c01943be7719f80b3592b44bc986f0 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 1.3E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10215 58c01943be7719f80b3592b44bc986f0 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 1.3E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10215 58c01943be7719f80b3592b44bc986f0 307 Gene3D G3DSA:3.40.190.10 92 183 2.9E-10 T 22-04-2016 TOLA_RS10215 58c01943be7719f80b3592b44bc986f0 307 Gene3D G3DSA:3.40.190.10 184 267 2.0E-5 T 22-04-2016 TOLA_RS10215 58c01943be7719f80b3592b44bc986f0 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 60 2.6E-16 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS00925 e2910f16247f22a69a127defa52d2385 523 PANTHER PTHR10283:SF93 194 509 5.4E-254 T 22-04-2016 TOLA_RS00925 e2910f16247f22a69a127defa52d2385 523 PANTHER PTHR10283:SF93 12 167 5.4E-254 T 22-04-2016 TOLA_RS00925 e2910f16247f22a69a127defa52d2385 523 Hamap MF_01599 Na(+)/H(+) antiporter NhaB [nhaB]. 1 523 332.126 T 22-04-2016 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 TOLA_RS00925 e2910f16247f22a69a127defa52d2385 523 TIGRFAM TIGR00774 NhaB: Na+/H+ antiporter NhaB 1 510 1.1E-258 T 22-04-2016 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 TOLA_RS00925 e2910f16247f22a69a127defa52d2385 523 Pfam PF06450 Bacterial Na+/H+ antiporter B (NhaB) 1 510 5.1E-259 T 22-04-2016 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 TOLA_RS00925 e2910f16247f22a69a127defa52d2385 523 PANTHER PTHR10283 194 509 5.4E-254 T 22-04-2016 TOLA_RS00925 e2910f16247f22a69a127defa52d2385 523 PANTHER PTHR10283 12 167 5.4E-254 T 22-04-2016 TOLA_RS10985 9c2043a12a8f063a98563c93872d6e54 317 Gene3D G3DSA:3.20.20.70 3 314 1.1E-127 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS10985 9c2043a12a8f063a98563c93872d6e54 317 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS10985 9c2043a12a8f063a98563c93872d6e54 317 TIGRFAM TIGR00874 talAB: transaldolase 4 315 2.3E-147 T 22-04-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS10985 9c2043a12a8f063a98563c93872d6e54 317 Pfam PF00923 Transaldolase 14 311 3.0E-100 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS10985 9c2043a12a8f063a98563c93872d6e54 317 PANTHER PTHR10683 2 316 4.6E-169 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS10985 9c2043a12a8f063a98563c93872d6e54 317 PANTHER PTHR10683:SF18 2 316 4.6E-169 T 22-04-2016 TOLA_RS10985 9c2043a12a8f063a98563c93872d6e54 317 Hamap MF_00492 Transaldolase [tal]. 2 316 50.736 T 22-04-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS10985 9c2043a12a8f063a98563c93872d6e54 317 ProSitePatterns PS00958 Transaldolase active site. 129 146 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS10985 9c2043a12a8f063a98563c93872d6e54 317 SUPERFAMILY SSF51569 2 315 8.37E-113 T 22-04-2016 TOLA_RS13260 b63093d5186ce5ea45403e64c962abd1 132 SUPERFAMILY SSF47175 27 130 9.3E-25 T 22-04-2016 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 TOLA_RS13260 b63093d5186ce5ea45403e64c962abd1 132 Gene3D G3DSA:1.20.120.10 26 130 1.6E-31 T 22-04-2016 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 TOLA_RS13260 b63093d5186ce5ea45403e64c962abd1 132 PIRSF PIRSF000029 1 130 1.2E-30 T 22-04-2016 IPR009155 Cytochrome b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900|GO:0042597 TOLA_RS13260 b63093d5186ce5ea45403e64c962abd1 132 Pfam PF07361 Cytochrome b562 27 129 6.6E-27 T 22-04-2016 IPR009155 Cytochrome b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900|GO:0042597 TOLA_RS11160 e362eb6ed1ac1087a4361af5d92324a5 195 PANTHER PTHR11746:SF102 124 186 3.3E-29 T 22-04-2016 TOLA_RS11160 e362eb6ed1ac1087a4361af5d92324a5 195 PANTHER PTHR11746 124 186 3.3E-29 T 22-04-2016 TOLA_RS11160 e362eb6ed1ac1087a4361af5d92324a5 195 Pfam PF02545 Maf-like protein 6 187 2.7E-44 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 TOLA_RS11160 e362eb6ed1ac1087a4361af5d92324a5 195 SUPERFAMILY SSF52972 3 187 4.84E-56 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like TOLA_RS11160 e362eb6ed1ac1087a4361af5d92324a5 195 PIRSF PIRSF006305 1 194 2.5E-39 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 TOLA_RS11160 e362eb6ed1ac1087a4361af5d92324a5 195 Gene3D G3DSA:3.90.950.10 5 190 6.0E-55 T 22-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like TOLA_RS11160 e362eb6ed1ac1087a4361af5d92324a5 195 TIGRFAM TIGR00172 maf: septum formation protein Maf 4 186 9.2E-54 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 TOLA_RS11160 e362eb6ed1ac1087a4361af5d92324a5 195 Hamap MF_00528 Septum formation protein Maf [maf]. 5 193 28.244 T 22-04-2016 IPR003697 Maf-like protein GO:0005737 TOLA_RS13200 c2e86b087367515b2d7fc78415ddc772 332 PANTHER PTHR10000 113 329 5.6E-89 T 22-04-2016 TOLA_RS13200 c2e86b087367515b2d7fc78415ddc772 332 Gene3D G3DSA:1.10.150.210 130 181 4.2E-27 T 22-04-2016 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|UniPathway: UPA00135 TOLA_RS13200 c2e86b087367515b2d7fc78415ddc772 332 SUPERFAMILY SSF56784 119 319 4.34E-48 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13200 c2e86b087367515b2d7fc78415ddc772 332 Pfam PF00702 haloacid dehalogenase-like hydrolase 120 291 7.9E-18 T 22-04-2016 TOLA_RS13200 c2e86b087367515b2d7fc78415ddc772 332 Gene3D G3DSA:3.40.50.1000 182 310 1.6E-37 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13200 c2e86b087367515b2d7fc78415ddc772 332 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 115 323 2.2E-78 T 22-04-2016 TOLA_RS13200 c2e86b087367515b2d7fc78415ddc772 332 PANTHER PTHR10000:SF7 113 329 5.6E-89 T 22-04-2016 TOLA_RS13200 c2e86b087367515b2d7fc78415ddc772 332 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 120 291 3.4E-26 T 22-04-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 TOLA_RS04370 76b6601d5844895f0ae484a8ba6d1d4f 239 Pfam PF02565 Recombination protein O C terminal 84 228 6.0E-15 T 22-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TOLA_RS04370 76b6601d5844895f0ae484a8ba6d1d4f 239 TIGRFAM TIGR00613 reco: DNA repair protein RecO 9 230 1.9E-24 T 22-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TOLA_RS04370 76b6601d5844895f0ae484a8ba6d1d4f 239 SUPERFAMILY SSF57863 86 150 5.49E-5 T 22-04-2016 TOLA_RS04370 76b6601d5844895f0ae484a8ba6d1d4f 239 Hamap MF_00201 DNA repair protein RecO [recO]. 3 233 20.287 T 22-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TOLA_RS04370 76b6601d5844895f0ae484a8ba6d1d4f 239 SUPERFAMILY SSF50249 7 77 2.57E-13 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS04370 76b6601d5844895f0ae484a8ba6d1d4f 239 Pfam PF11967 Recombination protein O N terminal 7 78 7.9E-20 T 22-04-2016 IPR022572 DNA replication/recombination mediator RecO, N-terminal TOLA_RS04370 76b6601d5844895f0ae484a8ba6d1d4f 239 PANTHER PTHR33991 3 237 3.7E-42 T 22-04-2016 TOLA_RS04370 76b6601d5844895f0ae484a8ba6d1d4f 239 Gene3D G3DSA:2.40.50.140 9 77 2.4E-8 T 22-04-2016 IPR012340 Nucleic acid-binding, OB-fold TOLA_RS05995 073bdc20dd020f1453bbd4b914525e5e 434 Gene3D G3DSA:1.10.443.10 244 406 8.5E-23 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS05995 073bdc20dd020f1453bbd4b914525e5e 434 Pfam PF00589 Phage integrase family 265 407 3.0E-15 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS05995 073bdc20dd020f1453bbd4b914525e5e 434 Pfam PF13356 Domain of unknown function (DUF4102) 6 93 6.4E-10 T 22-04-2016 IPR025166 Domain of unknown function DUF4102 TOLA_RS05995 073bdc20dd020f1453bbd4b914525e5e 434 SUPERFAMILY SSF56349 112 416 1.96E-33 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TOLA_RS05995 073bdc20dd020f1453bbd4b914525e5e 434 PANTHER PTHR30629:SF4 1 144 4.8E-80 T 22-04-2016 TOLA_RS05995 073bdc20dd020f1453bbd4b914525e5e 434 PANTHER PTHR30629:SF4 166 434 4.8E-80 T 22-04-2016 TOLA_RS05995 073bdc20dd020f1453bbd4b914525e5e 434 PANTHER PTHR30629 1 144 4.8E-80 T 22-04-2016 TOLA_RS05995 073bdc20dd020f1453bbd4b914525e5e 434 PANTHER PTHR30629 166 434 4.8E-80 T 22-04-2016 TOLA_RS09210 4001a44cce6fed807b0c1112889512f2 92 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 2 89 1.5E-16 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TOLA_RS09210 4001a44cce6fed807b0c1112889512f2 92 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 1 89 2.7E-12 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TOLA_RS09210 4001a44cce6fed807b0c1112889512f2 92 PANTHER PTHR33755:SF6 1 92 3.6E-36 T 22-04-2016 TOLA_RS09210 4001a44cce6fed807b0c1112889512f2 92 PANTHER PTHR33755 1 92 3.6E-36 T 22-04-2016 TOLA_RS08255 b0562afd6ad8200d056263bb7ac9d16c 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 35.539 T 22-04-2016 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08255 b0562afd6ad8200d056263bb7ac9d16c 100 SUPERFAMILY SSF54111 1 99 1.44E-46 T 22-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08255 b0562afd6ad8200d056263bb7ac9d16c 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 1.0E-33 T 22-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08255 b0562afd6ad8200d056263bb7ac9d16c 100 PANTHER PTHR33569:SF1 2 100 3.2E-46 T 22-04-2016 TOLA_RS08255 b0562afd6ad8200d056263bb7ac9d16c 100 Pfam PF00547 Urease, gamma subunit 1 99 6.4E-48 T 22-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08255 b0562afd6ad8200d056263bb7ac9d16c 100 PANTHER PTHR33569 2 100 3.2E-46 T 22-04-2016 TOLA_RS08255 b0562afd6ad8200d056263bb7ac9d16c 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 5.6E-53 T 22-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08255 b0562afd6ad8200d056263bb7ac9d16c 100 Gene3D G3DSA:3.30.280.10 1 99 1.8E-49 T 22-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS08255 b0562afd6ad8200d056263bb7ac9d16c 100 PIRSF PIRSF001223 1 100 1.4E-51 T 22-04-2016 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 TOLA_RS00665 3965dc0ea94ac12a51a1678bcefa172e 386 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 380 4.1E-146 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS00665 3965dc0ea94ac12a51a1678bcefa172e 386 Gene3D G3DSA:3.90.1150.10 247 381 3.2E-52 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS00665 3965dc0ea94ac12a51a1678bcefa172e 386 TIGRFAM TIGR02080 O_succ_thio_ly: O-succinylhomoserine (thiol)-lyase 5 382 8.1E-196 T 22-04-2016 IPR011821 O-succinylhomoserine (thiol)-lyase KEGG: 00270+2.5.1.48|KEGG: 00450+2.5.1.48|KEGG: 00920+2.5.1.48|UniPathway: UPA00051 TOLA_RS00665 3965dc0ea94ac12a51a1678bcefa172e 386 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 190 204 - T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS00665 3965dc0ea94ac12a51a1678bcefa172e 386 PANTHER PTHR11808 5 385 8.2E-191 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS00665 3965dc0ea94ac12a51a1678bcefa172e 386 Gene3D G3DSA:3.40.640.10 6 246 1.2E-89 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS00665 3965dc0ea94ac12a51a1678bcefa172e 386 SUPERFAMILY SSF53383 6 381 7.23E-120 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS00665 3965dc0ea94ac12a51a1678bcefa172e 386 PIRSF PIRSF001434 1 384 1.1E-137 T 22-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 TOLA_RS00665 3965dc0ea94ac12a51a1678bcefa172e 386 PANTHER PTHR11808:SF15 5 385 8.2E-191 T 22-04-2016 TOLA_RS15135 80b31642dea6c0fc904e14cfa2ae6892 134 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 29 117 3.6E-17 T 22-04-2016 IPR031982 Type IV minor pilin ComP TOLA_RS15135 80b31642dea6c0fc904e14cfa2ae6892 134 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 26 1.0E-6 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS15135 80b31642dea6c0fc904e14cfa2ae6892 134 Gene3D G3DSA:3.30.700.10 9 104 9.7E-12 T 22-04-2016 TOLA_RS15135 80b31642dea6c0fc904e14cfa2ae6892 134 PANTHER PTHR30093:SF4 6 103 1.8E-15 T 22-04-2016 TOLA_RS15135 80b31642dea6c0fc904e14cfa2ae6892 134 SUPERFAMILY SSF54523 9 126 1.73E-17 T 22-04-2016 TOLA_RS15135 80b31642dea6c0fc904e14cfa2ae6892 134 PRINTS PR00813 Bacterial general secretion pathway protein G signature 43 61 7.8E-6 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 TOLA_RS15135 80b31642dea6c0fc904e14cfa2ae6892 134 PRINTS PR00813 Bacterial general secretion pathway protein G signature 7 32 7.8E-6 T 22-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 TOLA_RS15135 80b31642dea6c0fc904e14cfa2ae6892 134 PANTHER PTHR30093 6 103 1.8E-15 T 22-04-2016 TOLA_RS15135 80b31642dea6c0fc904e14cfa2ae6892 134 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS03775 3805f3aced8bcd0c910d9267fef94a24 95 Gene3D G3DSA:1.10.10.10 5 72 1.2E-4 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS03775 3805f3aced8bcd0c910d9267fef94a24 95 SUPERFAMILY SSF46785 4 74 6.98E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11535 c35a4f8cdfa542d0326d0b89bff5160b 331 Gene3D G3DSA:1.10.10.10 276 315 1.9E-7 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11535 c35a4f8cdfa542d0326d0b89bff5160b 331 SUPERFAMILY SSF46785 275 328 5.66E-6 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS11535 c35a4f8cdfa542d0326d0b89bff5160b 331 Gene3D G3DSA:1.10.3290.10 19 253 9.4E-58 T 22-04-2016 IPR003812 Fido domain TOLA_RS11535 c35a4f8cdfa542d0326d0b89bff5160b 331 Pfam PF02661 Fic/DOC family 101 196 4.3E-23 T 22-04-2016 IPR003812 Fido domain TOLA_RS11535 c35a4f8cdfa542d0326d0b89bff5160b 331 PANTHER PTHR13504:SF32 38 313 4.3E-42 T 22-04-2016 TOLA_RS11535 c35a4f8cdfa542d0326d0b89bff5160b 331 Pfam PF13412 Winged helix-turn-helix DNA-binding 276 315 4.2E-6 T 22-04-2016 TOLA_RS11535 c35a4f8cdfa542d0326d0b89bff5160b 331 SUPERFAMILY SSF140931 79 255 2.35E-42 T 22-04-2016 IPR003812 Fido domain TOLA_RS11535 c35a4f8cdfa542d0326d0b89bff5160b 331 PANTHER PTHR13504 38 313 4.3E-42 T 22-04-2016 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 Gene3D G3DSA:1.10.287.80 236 282 2.9E-31 T 22-04-2016 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 Gene3D G3DSA:1.10.287.80 202 235 5.3E-37 T 22-04-2016 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 Gene3D G3DSA:1.10.287.80 19 60 5.3E-37 T 22-04-2016 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 PANTHER PTHR11693 1 287 4.4E-131 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 Gene3D G3DSA:3.40.1380.10 63 191 1.7E-42 T 22-04-2016 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 Pfam PF00231 ATP synthase 5 286 8.4E-91 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 273 286 - T 22-04-2016 IPR023632 ATPase, F1 complex, gamma subunit conserved site TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 287 1.0E-109 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 9.24E-39 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 PRINTS PR00126 ATP synthase gamma subunit signature 265 286 9.24E-39 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 9.24E-39 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 PRINTS PR00126 ATP synthase gamma subunit signature 234 253 9.24E-39 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 287 36.406 T 22-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 TOLA_RS16080 4e3adf581dcdd8795f62c335187db4a0 287 SUPERFAMILY SSF52943 2 287 5.23E-97 T 22-04-2016 IPR023633 ATPase, F1 complex, gamma subunit domain TOLA_RS03790 8231a040fb87cad2cc2bf5c4c8ab9b3a 521 Pfam PF06074 Protein of unknown function (DUF935) 3 515 1.1E-196 T 22-04-2016 IPR009279 Protein of unknown function DUF935 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 PRINTS PR00344 Bacterial sensor protein C-terminal signature 818 832 6.9E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 PRINTS PR00344 Bacterial sensor protein C-terminal signature 853 871 6.9E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 PRINTS PR00344 Bacterial sensor protein C-terminal signature 836 846 6.9E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 PRINTS PR00344 Bacterial sensor protein C-terminal signature 877 890 6.9E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 Gene3D G3DSA:3.40.50.2300 915 1033 2.6E-27 T 22-04-2016 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 Pfam PF00512 His Kinase A (phospho-acceptor) domain 669 735 5.5E-17 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 SUPERFAMILY SSF52172 916 1039 7.12E-28 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 PANTHER PTHR24423:SF382 491 528 1.3E-113 T 22-04-2016 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 PANTHER PTHR24423:SF382 6 35 1.3E-113 T 22-04-2016 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 PANTHER PTHR24423:SF382 648 1069 1.3E-113 T 22-04-2016 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 Pfam PF00072 Response regulator receiver domain 918 1027 7.3E-21 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 PANTHER PTHR24423 491 528 1.3E-113 T 22-04-2016 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 PANTHER PTHR24423 6 35 1.3E-113 T 22-04-2016 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 PANTHER PTHR24423 648 1069 1.3E-113 T 22-04-2016 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 782 889 2.4E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 SMART SM00387 782 893 1.4E-32 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 Gene3D G3DSA:3.30.565.10 736 890 8.9E-44 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 Gene3D G3DSA:1.10.287.130 662 731 2.0E-14 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 SUPERFAMILY SSF55874 725 889 4.71E-43 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 SUPERFAMILY SSF47384 655 736 1.0E-19 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 SMART SM00448 916 1027 3.6E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS08290 d710c5f99b771da730d4161a96ad3c73 1125 SMART SM00388 669 735 5.4E-21 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS08365 d3205502da2f8f10b7ddc4867ac1bc00 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 62 7.1E-16 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS08365 d3205502da2f8f10b7ddc4867ac1bc00 303 PANTHER PTHR30537 1 301 1.3E-100 T 22-04-2016 TOLA_RS08365 d3205502da2f8f10b7ddc4867ac1bc00 303 Gene3D G3DSA:3.40.190.10 92 192 3.0E-25 T 22-04-2016 TOLA_RS08365 d3205502da2f8f10b7ddc4867ac1bc00 303 SUPERFAMILY SSF53850 88 296 1.07E-45 T 22-04-2016 TOLA_RS08365 d3205502da2f8f10b7ddc4867ac1bc00 303 Pfam PF03466 LysR substrate binding domain 88 293 5.7E-44 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS08365 d3205502da2f8f10b7ddc4867ac1bc00 303 Gene3D G3DSA:1.10.10.10 8 86 8.8E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08365 d3205502da2f8f10b7ddc4867ac1bc00 303 PANTHER PTHR30537:SF5 1 301 1.3E-100 T 22-04-2016 TOLA_RS08365 d3205502da2f8f10b7ddc4867ac1bc00 303 SUPERFAMILY SSF46785 6 111 1.14E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14740 7cf846d6503644c5b56c97ec1243352e 292 SUPERFAMILY SSF46785 7 112 1.61E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14740 7cf846d6503644c5b56c97ec1243352e 292 Gene3D G3DSA:3.40.190.10 178 256 2.9E-19 T 22-04-2016 TOLA_RS14740 7cf846d6503644c5b56c97ec1243352e 292 Pfam PF03466 LysR substrate binding domain 89 287 9.2E-51 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS14740 7cf846d6503644c5b56c97ec1243352e 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 63 2.4E-18 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS14740 7cf846d6503644c5b56c97ec1243352e 292 Gene3D G3DSA:1.10.10.10 8 87 2.7E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14740 7cf846d6503644c5b56c97ec1243352e 292 PANTHER PTHR30537:SF10 1 288 2.2E-143 T 22-04-2016 TOLA_RS14740 7cf846d6503644c5b56c97ec1243352e 292 SUPERFAMILY SSF53850 89 289 7.78E-52 T 22-04-2016 TOLA_RS14740 7cf846d6503644c5b56c97ec1243352e 292 Gene3D G3DSA:3.40.190.10 92 177 4.5E-24 T 22-04-2016 TOLA_RS14740 7cf846d6503644c5b56c97ec1243352e 292 PANTHER PTHR30537 1 288 2.2E-143 T 22-04-2016 TOLA_RS13625 7cbd792188558e6e37d5c08ed61936cb 237 PANTHER PTHR36180:SF1 15 122 5.1E-31 T 22-04-2016 TOLA_RS13625 7cbd792188558e6e37d5c08ed61936cb 237 Pfam PF08346 AntA/AntB antirepressor 20 93 2.1E-29 T 22-04-2016 IPR013557 AntA/AntB antirepressor TOLA_RS13625 7cbd792188558e6e37d5c08ed61936cb 237 PANTHER PTHR36180 15 122 5.1E-31 T 22-04-2016 TOLA_RS14680 5d1880928836fa01c1ead39a86dc11ff 351 Hamap MF_02030 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase [wecA]. 7 350 26.907 T 22-04-2016 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530|UniPathway: UPA00281 TOLA_RS14680 5d1880928836fa01c1ead39a86dc11ff 351 PANTHER PTHR22926 7 351 5.2E-75 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS14680 5d1880928836fa01c1ead39a86dc11ff 351 Pfam PF00953 Glycosyl transferase family 4 74 232 1.5E-28 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS14680 5d1880928836fa01c1ead39a86dc11ff 351 PANTHER PTHR22926:SF3 7 351 5.2E-75 T 22-04-2016 TOLA_RS14680 5d1880928836fa01c1ead39a86dc11ff 351 TIGRFAM TIGR02380 ECA_wecA: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase 7 347 2.1E-119 T 22-04-2016 IPR012750 Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase GO:0000287|GO:0009103|GO:0009276|GO:0016021|GO:0016780|GO:0030145 MetaCyc: PWY-7290|MetaCyc: PWY-7530|UniPathway: UPA00281 TOLA_RS16360 f76a07784d83541a0b8dea657a06975c 392 Gene3D G3DSA:3.30.70.270 226 389 8.7E-56 T 22-04-2016 TOLA_RS16360 f76a07784d83541a0b8dea657a06975c 392 PANTHER PTHR10799:SF686 258 385 1.3E-30 T 22-04-2016 TOLA_RS16360 f76a07784d83541a0b8dea657a06975c 392 PANTHER PTHR10799:SF686 53 173 1.3E-30 T 22-04-2016 TOLA_RS16360 f76a07784d83541a0b8dea657a06975c 392 Pfam PF00990 Diguanylate cyclase, GGDEF domain 224 384 1.7E-48 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16360 f76a07784d83541a0b8dea657a06975c 392 SMART SM00267 213 388 6.1E-60 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS16360 f76a07784d83541a0b8dea657a06975c 392 PANTHER PTHR10799 258 385 1.3E-30 T 22-04-2016 TOLA_RS16360 f76a07784d83541a0b8dea657a06975c 392 PANTHER PTHR10799 53 173 1.3E-30 T 22-04-2016 TOLA_RS16360 f76a07784d83541a0b8dea657a06975c 392 SUPERFAMILY SSF55073 229 388 1.26E-47 T 22-04-2016 IPR029787 Nucleotide cyclase TOLA_RS16360 f76a07784d83541a0b8dea657a06975c 392 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 222 386 1.9E-52 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS12420 3ff7fb847ae464c98cd4510a879d7abb 300 Pfam PF11920 Protein of unknown function (DUF3438) 8 280 2.2E-127 T 22-04-2016 IPR021844 Integrating conjugative element protein, PFL4704 TOLA_RS12420 3ff7fb847ae464c98cd4510a879d7abb 300 TIGRFAM TIGR03749 conj_TIGR03749: integrating conjugative element protein, PFL_4704 family 13 271 6.0E-113 T 22-04-2016 IPR021844 Integrating conjugative element protein, PFL4704 TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 PANTHER PTHR22855:SF42 1 317 8.9E-128 T 22-04-2016 TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 SUPERFAMILY SSF52096 5 317 1.13E-103 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 150 3.9E-64 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 199 208 1.7E-49 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 115 133 1.7E-49 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 155 168 1.7E-49 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 90 101 1.7E-49 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 136 152 1.7E-49 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 171 184 1.7E-49 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 318 50.268 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 PANTHER PTHR22855 1 317 8.9E-128 T 22-04-2016 TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 Gene3D G3DSA:3.90.226.10 58 286 1.1E-50 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS10655 882c2e19d8bbd3713b31fa4760ed6a25 318 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 1 318 2.4E-162 T 22-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 TOLA_RS06240 9f6293ac8456cf98c3775f9b9fb9f498 567 SUPERFAMILY SSF53335 96 566 1.88E-136 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS06240 9f6293ac8456cf98c3775f9b9fb9f498 567 SUPERFAMILY SSF53335 10 49 1.88E-136 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS06240 9f6293ac8456cf98c3775f9b9fb9f498 567 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 353 377 8.4E-20 T 22-04-2016 TOLA_RS06240 9f6293ac8456cf98c3775f9b9fb9f498 567 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 237 251 8.4E-20 T 22-04-2016 TOLA_RS06240 9f6293ac8456cf98c3775f9b9fb9f498 567 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 319 331 8.4E-20 T 22-04-2016 TOLA_RS06240 9f6293ac8456cf98c3775f9b9fb9f498 567 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 214 230 8.4E-20 T 22-04-2016 TOLA_RS06240 9f6293ac8456cf98c3775f9b9fb9f498 567 Gene3D G3DSA:3.40.50.150 216 465 9.8E-32 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS06240 9f6293ac8456cf98c3775f9b9fb9f498 567 Pfam PF12161 HsdM N-terminal domain 12 178 9.3E-23 T 22-04-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain TOLA_RS06240 9f6293ac8456cf98c3775f9b9fb9f498 567 Pfam PF02384 N-6 DNA Methylase 190 526 1.4E-113 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TOLA_RS06240 9f6293ac8456cf98c3775f9b9fb9f498 567 PANTHER PTHR30408 166 546 2.1E-181 T 22-04-2016 TOLA_RS06240 9f6293ac8456cf98c3775f9b9fb9f498 567 PANTHER PTHR30408:SF8 166 546 2.1E-181 T 22-04-2016 TOLA_RS10020 b63eedf9b91b87879d46438a2bdeadbc 303 PANTHER PTHR18964:SF10 9 300 1.3E-45 T 22-04-2016 TOLA_RS10020 b63eedf9b91b87879d46438a2bdeadbc 303 PANTHER PTHR18964 9 300 1.3E-45 T 22-04-2016 TOLA_RS10020 b63eedf9b91b87879d46438a2bdeadbc 303 Gene3D G3DSA:3.30.420.40 146 274 6.2E-32 T 22-04-2016 TOLA_RS10020 b63eedf9b91b87879d46438a2bdeadbc 303 Pfam PF00480 ROK family 9 297 1.5E-67 T 22-04-2016 IPR000600 ROK family TOLA_RS10020 b63eedf9b91b87879d46438a2bdeadbc 303 SUPERFAMILY SSF53067 9 297 3.58E-42 T 22-04-2016 TOLA_RS10020 b63eedf9b91b87879d46438a2bdeadbc 303 Gene3D G3DSA:3.30.420.40 6 145 4.9E-20 T 22-04-2016 TOLA_RS16260 da566a0af635d6268b15eb1621ce0a2b 251 Gene3D G3DSA:1.10.260.40 9 70 7.2E-6 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS16260 da566a0af635d6268b15eb1621ce0a2b 251 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 11 65 3.4E-8 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS16260 da566a0af635d6268b15eb1621ce0a2b 251 SUPERFAMILY SSF47413 5 65 7.16E-7 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS16260 da566a0af635d6268b15eb1621ce0a2b 251 SMART SM00530 10 64 0.0011 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS09000 601fae3ab9c8a4c505e90d7e98285198 312 PANTHER PTHR30151:SF7 98 312 2.5E-91 T 22-04-2016 TOLA_RS09000 601fae3ab9c8a4c505e90d7e98285198 312 PANTHER PTHR30151:SF7 6 58 2.5E-91 T 22-04-2016 TOLA_RS09000 601fae3ab9c8a4c505e90d7e98285198 312 Gene3D G3DSA:1.10.3720.10 95 303 3.5E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09000 601fae3ab9c8a4c505e90d7e98285198 312 PANTHER PTHR30151 98 312 2.5E-91 T 22-04-2016 TOLA_RS09000 601fae3ab9c8a4c505e90d7e98285198 312 PANTHER PTHR30151 6 58 2.5E-91 T 22-04-2016 TOLA_RS09000 601fae3ab9c8a4c505e90d7e98285198 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 289 7.2E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09000 601fae3ab9c8a4c505e90d7e98285198 312 SUPERFAMILY SSF161098 96 293 5.36E-24 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09640 bf4ae9bdb85286cffe1728295127d6e3 282 Gene3D G3DSA:1.10.10.60 229 279 6.3E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09640 bf4ae9bdb85286cffe1728295127d6e3 282 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 229 271 - T 22-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 TOLA_RS09640 bf4ae9bdb85286cffe1728295127d6e3 282 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 275 2.0E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS09640 bf4ae9bdb85286cffe1728295127d6e3 282 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 244 259 2.0E-6 T 22-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 TOLA_RS09640 bf4ae9bdb85286cffe1728295127d6e3 282 PANTHER PTHR11019:SF11 36 282 5.9E-57 T 22-04-2016 TOLA_RS09640 bf4ae9bdb85286cffe1728295127d6e3 282 SUPERFAMILY SSF46689 177 225 1.52E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09640 bf4ae9bdb85286cffe1728295127d6e3 282 Gene3D G3DSA:1.10.10.60 173 228 4.0E-14 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09640 bf4ae9bdb85286cffe1728295127d6e3 282 PANTHER PTHR11019 36 282 5.9E-57 T 22-04-2016 TOLA_RS09640 bf4ae9bdb85286cffe1728295127d6e3 282 SUPERFAMILY SSF46689 228 278 1.34E-13 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09640 bf4ae9bdb85286cffe1728295127d6e3 282 SMART SM00342 192 275 5.6E-32 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS09640 bf4ae9bdb85286cffe1728295127d6e3 282 Pfam PF12833 Helix-turn-helix domain 198 275 1.2E-20 T 22-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 TOLA_RS09045 70ecbc7ca4b029953e2460449614bbde 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 287 1.7E-64 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TOLA_RS09045 70ecbc7ca4b029953e2460449614bbde 324 Gene3D G3DSA:3.40.50.720 113 287 1.1E-68 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09045 70ecbc7ca4b029953e2460449614bbde 324 SUPERFAMILY SSF51735 100 288 8.29E-61 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09045 70ecbc7ca4b029953e2460449614bbde 324 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 148 176 - T 22-04-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TOLA_RS09045 70ecbc7ca4b029953e2460449614bbde 324 Gene3D G3DSA:3.40.50.720 2 112 1.3E-30 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS09045 70ecbc7ca4b029953e2460449614bbde 324 PANTHER PTHR10996:SF118 1 324 2.1E-138 T 22-04-2016 TOLA_RS09045 70ecbc7ca4b029953e2460449614bbde 324 SUPERFAMILY SSF52283 1 134 2.76E-29 T 22-04-2016 TOLA_RS09045 70ecbc7ca4b029953e2460449614bbde 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 319 4.9E-27 T 22-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 TOLA_RS09045 70ecbc7ca4b029953e2460449614bbde 324 PANTHER PTHR10996 1 324 2.1E-138 T 22-04-2016 TOLA_RS15195 def7d4e3ab2b4842d0ec6009057a45e5 174 PANTHER PTHR23114 1 159 4.2E-57 T 22-04-2016 TOLA_RS15195 def7d4e3ab2b4842d0ec6009057a45e5 174 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 157 36.996 T 22-04-2016 IPR022927 RNA pyrophosphohydrolase RppH TOLA_RS15195 def7d4e3ab2b4842d0ec6009057a45e5 174 Pfam PF00293 NUDIX domain 7 147 5.9E-26 T 22-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TOLA_RS15195 def7d4e3ab2b4842d0ec6009057a45e5 174 PRINTS PR00502 NUDIX hydrolase family signature 33 47 7.2E-8 T 22-04-2016 IPR020476 NUDIX hydrolase TOLA_RS15195 def7d4e3ab2b4842d0ec6009057a45e5 174 PRINTS PR00502 NUDIX hydrolase family signature 47 62 7.2E-8 T 22-04-2016 IPR020476 NUDIX hydrolase TOLA_RS15195 def7d4e3ab2b4842d0ec6009057a45e5 174 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 22-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TOLA_RS15195 def7d4e3ab2b4842d0ec6009057a45e5 174 SUPERFAMILY SSF55811 7 155 3.66E-33 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS15195 def7d4e3ab2b4842d0ec6009057a45e5 174 Gene3D G3DSA:3.90.79.10 5 152 6.0E-32 T 22-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TOLA_RS10120 c9544d7002b61658dc90507a036f2c81 297 Gene3D G3DSA:3.40.190.10 87 153 3.5E-4 T 22-04-2016 TOLA_RS10120 c9544d7002b61658dc90507a036f2c81 297 Pfam PF03466 LysR substrate binding domain 90 294 8.2E-31 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS10120 c9544d7002b61658dc90507a036f2c81 297 SUPERFAMILY SSF46785 5 90 2.61E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10120 c9544d7002b61658dc90507a036f2c81 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 5.9E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10120 c9544d7002b61658dc90507a036f2c81 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 5.9E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10120 c9544d7002b61658dc90507a036f2c81 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 5.9E-6 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10120 c9544d7002b61658dc90507a036f2c81 297 SUPERFAMILY SSF53850 91 294 4.89E-37 T 22-04-2016 TOLA_RS10120 c9544d7002b61658dc90507a036f2c81 297 Gene3D G3DSA:3.40.190.10 163 265 8.0E-19 T 22-04-2016 TOLA_RS10120 c9544d7002b61658dc90507a036f2c81 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.6E-19 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS10120 c9544d7002b61658dc90507a036f2c81 297 PANTHER PTHR30537:SF1 1 296 2.0E-163 T 22-04-2016 TOLA_RS10120 c9544d7002b61658dc90507a036f2c81 297 PANTHER PTHR30537 1 296 2.0E-163 T 22-04-2016 TOLA_RS10120 c9544d7002b61658dc90507a036f2c81 297 Gene3D G3DSA:1.10.10.10 5 86 4.7E-23 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS04765 ef80a661169fea2892f95feabd2a2e35 188 PANTHER PTHR37528 1 188 1.8E-31 T 22-04-2016 TOLA_RS04765 ef80a661169fea2892f95feabd2a2e35 188 SUPERFAMILY SSF101327 8 174 8.37E-35 T 22-04-2016 IPR011978 Uncharacterised protein family UPF0149 TOLA_RS04765 ef80a661169fea2892f95feabd2a2e35 188 Pfam PF03695 Uncharacterised protein family (UPF0149) 13 175 3.3E-31 T 22-04-2016 IPR011978 Uncharacterised protein family UPF0149 TOLA_RS15995 83dbf870d1eb7dc67f62970079c74456 489 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 244 432 5.1E-56 T 22-04-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 TOLA_RS15995 83dbf870d1eb7dc67f62970079c74456 489 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 1 475 1.1E-148 T 22-04-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 TOLA_RS15995 83dbf870d1eb7dc67f62970079c74456 489 Gene3D G3DSA:3.40.50.300 1 236 1.3E-48 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15995 83dbf870d1eb7dc67f62970079c74456 489 PANTHER PTHR21343:SF1 1 480 3.8E-220 T 22-04-2016 TOLA_RS15995 83dbf870d1eb7dc67f62970079c74456 489 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 483 202.057 T 22-04-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 TOLA_RS15995 83dbf870d1eb7dc67f62970079c74456 489 SUPERFAMILY SSF52540 1 239 2.13E-55 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15995 83dbf870d1eb7dc67f62970079c74456 489 PANTHER PTHR21343 1 480 3.8E-220 T 22-04-2016 TOLA_RS15995 83dbf870d1eb7dc67f62970079c74456 489 SUPERFAMILY SSF52317 245 442 3.97E-38 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS15995 83dbf870d1eb7dc67f62970079c74456 489 Gene3D G3DSA:3.40.50.880 243 442 2.7E-28 T 22-04-2016 IPR029062 Class I glutamine amidotransferase-like TOLA_RS15995 83dbf870d1eb7dc67f62970079c74456 489 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 1 224 5.9E-29 T 22-04-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TOLA_RS03125 b368ee2f8758f06d8eced2ed10bf24bd 182 Pfam PF04891 NifQ 19 179 4.5E-47 T 22-04-2016 IPR006975 NifQ GO:0009399|GO:0030151 TOLA_RS07610 803799a0b0cacd1385de08b729605f7e 283 PRINTS PR01438 Universal stress protein signature 261 283 8.9E-10 T 22-04-2016 IPR006015 Universal stress protein A TOLA_RS07610 803799a0b0cacd1385de08b729605f7e 283 PRINTS PR01438 Universal stress protein signature 243 255 8.9E-10 T 22-04-2016 IPR006015 Universal stress protein A TOLA_RS07610 803799a0b0cacd1385de08b729605f7e 283 PRINTS PR01438 Universal stress protein signature 167 185 8.9E-10 T 22-04-2016 IPR006015 Universal stress protein A TOLA_RS07610 803799a0b0cacd1385de08b729605f7e 283 Pfam PF00582 Universal stress protein family 215 283 9.2E-10 T 22-04-2016 IPR006016 UspA GO:0006950 TOLA_RS07610 803799a0b0cacd1385de08b729605f7e 283 Pfam PF00582 Universal stress protein family 3 159 1.1E-9 T 22-04-2016 IPR006016 UspA GO:0006950 TOLA_RS07610 803799a0b0cacd1385de08b729605f7e 283 SUPERFAMILY SSF52402 167 283 3.1E-18 T 22-04-2016 TOLA_RS07610 803799a0b0cacd1385de08b729605f7e 283 Gene3D G3DSA:3.40.50.620 210 283 5.0E-16 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS07610 803799a0b0cacd1385de08b729605f7e 283 Gene3D G3DSA:3.40.50.620 2 159 1.8E-16 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS07610 803799a0b0cacd1385de08b729605f7e 283 SUPERFAMILY SSF52402 2 159 3.85E-14 T 22-04-2016 TOLA_RS15945 5a6cbac3b406efec45fbe7639ecd7934 532 PRINTS PR00878 Cholinesterase signature 132 161 2.0E-5 T 22-04-2016 IPR000997 Cholinesterase GO:0004104 TOLA_RS15945 5a6cbac3b406efec45fbe7639ecd7934 532 PRINTS PR00878 Cholinesterase signature 441 453 2.0E-5 T 22-04-2016 IPR000997 Cholinesterase GO:0004104 TOLA_RS15945 5a6cbac3b406efec45fbe7639ecd7934 532 PANTHER PTHR11559 11 508 1.4E-151 T 22-04-2016 TOLA_RS15945 5a6cbac3b406efec45fbe7639ecd7934 532 Gene3D G3DSA:3.40.50.1820 27 531 3.6E-141 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS15945 5a6cbac3b406efec45fbe7639ecd7934 532 Pfam PF00135 Carboxylesterase family 31 509 2.0E-116 T 22-04-2016 IPR002018 Carboxylesterase, type B TOLA_RS15945 5a6cbac3b406efec45fbe7639ecd7934 532 SUPERFAMILY SSF53474 31 529 4.36E-123 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS04850 49d2eddb72b28e397b9488a4f15736ce 287 Pfam PF02811 PHP domain 4 85 1.5E-7 T 22-04-2016 IPR004013 PHP domain GO:0003824 TOLA_RS04850 49d2eddb72b28e397b9488a4f15736ce 287 PANTHER PTHR30007:SF4 1 272 5.1E-86 T 22-04-2016 TOLA_RS04850 49d2eddb72b28e397b9488a4f15736ce 287 SMART SM00481 3 70 3.3E-17 T 22-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 TOLA_RS04850 49d2eddb72b28e397b9488a4f15736ce 287 PANTHER PTHR30007 1 272 5.1E-86 T 22-04-2016 TOLA_RS04850 49d2eddb72b28e397b9488a4f15736ce 287 SUPERFAMILY SSF89550 165 275 8.24E-52 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 TOLA_RS04850 49d2eddb72b28e397b9488a4f15736ce 287 SUPERFAMILY SSF89550 1 83 8.24E-52 T 22-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 TOLA_RS04850 49d2eddb72b28e397b9488a4f15736ce 287 Gene3D G3DSA:3.20.20.140 157 266 1.7E-42 T 22-04-2016 TOLA_RS04850 49d2eddb72b28e397b9488a4f15736ce 287 Gene3D G3DSA:3.20.20.140 1 88 1.7E-42 T 22-04-2016 TOLA_RS08305 a9f171ed08608b51e83b1f15df4258bd 266 Gene3D G3DSA:3.40.50.300 16 261 1.2E-78 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08305 a9f171ed08608b51e83b1f15df4258bd 266 PIRSF PIRSF039085 12 266 4.7E-115 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TOLA_RS08305 a9f171ed08608b51e83b1f15df4258bd 266 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS08305 a9f171ed08608b51e83b1f15df4258bd 266 Pfam PF00005 ABC transporter 31 190 9.3E-33 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS08305 a9f171ed08608b51e83b1f15df4258bd 266 PANTHER PTHR24220:SF472 17 262 1.2E-138 T 22-04-2016 TOLA_RS08305 a9f171ed08608b51e83b1f15df4258bd 266 SMART SM00382 40 238 3.3E-15 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS08305 a9f171ed08608b51e83b1f15df4258bd 266 PANTHER PTHR24220 17 262 1.2E-138 T 22-04-2016 TOLA_RS08305 a9f171ed08608b51e83b1f15df4258bd 266 SUPERFAMILY SSF52540 16 260 6.44E-74 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04025 b4dee9d979078fc1e84eb1daa862455e 326 Hamap MF_01590 tRNA (mo5U34)-methyltransferase [cmoB]. 12 322 54.348 T 22-04-2016 IPR010017 tRNA (mo5U34)-methyltransferase GO:0002098|GO:0016300 TOLA_RS04025 b4dee9d979078fc1e84eb1daa862455e 326 PANTHER PTHR10108:SF847 53 324 1.5E-129 T 22-04-2016 TOLA_RS04025 b4dee9d979078fc1e84eb1daa862455e 326 SUPERFAMILY SSF53335 91 323 1.91E-34 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04025 b4dee9d979078fc1e84eb1daa862455e 326 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 7 321 1.3E-151 T 22-04-2016 IPR010017 tRNA (mo5U34)-methyltransferase GO:0002098|GO:0016300 TOLA_RS04025 b4dee9d979078fc1e84eb1daa862455e 326 PANTHER PTHR10108 53 324 1.5E-129 T 22-04-2016 TOLA_RS04025 b4dee9d979078fc1e84eb1daa862455e 326 Pfam PF08003 Protein of unknown function (DUF1698) 7 321 4.1E-157 T 22-04-2016 IPR027555 tRNA (mo5U34)-methyltransferase-like TOLA_RS04025 b4dee9d979078fc1e84eb1daa862455e 326 Gene3D G3DSA:3.40.50.150 97 282 2.2E-26 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS07285 cb778e7332f626aa5773ae579731bfae 92 Gene3D G3DSA:3.10.20.30 3 81 4.6E-19 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS07285 cb778e7332f626aa5773ae579731bfae 92 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 75 1.9E-11 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TOLA_RS07285 cb778e7332f626aa5773ae579731bfae 92 SUPERFAMILY SSF54292 3 82 3.41E-21 T 22-04-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 TOLA_RS07285 cb778e7332f626aa5773ae579731bfae 92 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 36 44 - T 22-04-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TOLA_RS15825 f43b548035972a4764a79ffa8ba53442 316 PANTHER PTHR34294:SF2 1 313 1.5E-114 T 22-04-2016 TOLA_RS15825 f43b548035972a4764a79ffa8ba53442 316 SUPERFAMILY SSF88659 16 47 9.48E-5 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15825 f43b548035972a4764a79ffa8ba53442 316 SUPERFAMILY SSF100950 58 314 1.09E-61 T 22-04-2016 TOLA_RS15825 f43b548035972a4764a79ffa8ba53442 316 Pfam PF04198 Putative sugar-binding domain 58 314 4.3E-64 T 22-04-2016 IPR007324 Sugar-binding domain, putative GO:0030246 TOLA_RS15825 f43b548035972a4764a79ffa8ba53442 316 PANTHER PTHR34294 1 313 1.5E-114 T 22-04-2016 TOLA_RS15825 f43b548035972a4764a79ffa8ba53442 316 Gene3D G3DSA:3.40.50.1360 56 313 7.9E-72 T 22-04-2016 TOLA_RS08525 8f3d982b27e2e004c11eae68100fd865 192 PANTHER PTHR14741:SF34 1 146 1.4E-41 T 22-04-2016 TOLA_RS08525 8f3d982b27e2e004c11eae68100fd865 192 Pfam PF03602 Conserved hypothetical protein 95 8 89 5.8E-8 T 22-04-2016 TOLA_RS08525 8f3d982b27e2e004c11eae68100fd865 192 SUPERFAMILY SSF53335 3 147 2.79E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS08525 8f3d982b27e2e004c11eae68100fd865 192 PANTHER PTHR14741 1 146 1.4E-41 T 22-04-2016 TOLA_RS08525 8f3d982b27e2e004c11eae68100fd865 192 Gene3D G3DSA:3.40.50.150 5 185 1.0E-28 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS08525 8f3d982b27e2e004c11eae68100fd865 192 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 13 132 3.0E-38 T 22-04-2016 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 TOLA_RS02730 45059d47f31df8bae5cd02bbda896b49 278 PANTHER PTHR35851:SF1 9 274 2.6E-54 T 22-04-2016 TOLA_RS02730 45059d47f31df8bae5cd02bbda896b49 278 PANTHER PTHR35851 9 274 2.6E-54 T 22-04-2016 TOLA_RS02730 45059d47f31df8bae5cd02bbda896b49 278 Pfam PF08478 POTRA domain, FtsQ-type 65 134 1.2E-16 T 22-04-2016 IPR013685 Polypeptide-transport-associated, FtsQ-type TOLA_RS02730 45059d47f31df8bae5cd02bbda896b49 278 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 34 257 19.993 T 22-04-2016 IPR026579 Cell division protein FtsQ GO:0000917 TOLA_RS02730 45059d47f31df8bae5cd02bbda896b49 278 Pfam PF03799 Cell division protein FtsQ 138 249 3.9E-22 T 22-04-2016 IPR005548 Cell division protein FtsQ/DivIB TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 SUPERFAMILY SSF53187 10 182 1.36E-60 T 22-04-2016 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 SUPERFAMILY SSF53187 397 481 1.36E-60 T 22-04-2016 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PANTHER PTHR11014:SF54 7 185 2.0E-160 T 22-04-2016 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PANTHER PTHR11014:SF54 204 279 2.0E-160 T 22-04-2016 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PANTHER PTHR11014:SF54 330 487 2.0E-160 T 22-04-2016 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PRINTS PR00934 X-His dipeptidase (M25) signature 428 444 2.9E-78 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PRINTS PR00934 X-His dipeptidase (M25) signature 251 270 2.9E-78 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PRINTS PR00934 X-His dipeptidase (M25) signature 206 223 2.9E-78 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PRINTS PR00934 X-His dipeptidase (M25) signature 363 381 2.9E-78 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PRINTS PR00934 X-His dipeptidase (M25) signature 159 177 2.9E-78 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PRINTS PR00934 X-His dipeptidase (M25) signature 135 152 2.9E-78 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PRINTS PR00934 X-His dipeptidase (M25) signature 450 472 2.9E-78 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PRINTS PR00934 X-His dipeptidase (M25) signature 101 119 2.9E-78 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PRINTS PR00934 X-His dipeptidase (M25) signature 80 99 2.9E-78 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PANTHER PTHR11014 7 185 2.0E-160 T 22-04-2016 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PANTHER PTHR11014 204 279 2.0E-160 T 22-04-2016 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PANTHER PTHR11014 330 487 2.0E-160 T 22-04-2016 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 Gene3D G3DSA:3.40.630.10 5 181 1.3E-101 T 22-04-2016 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 Gene3D G3DSA:3.40.630.10 397 483 1.3E-101 T 22-04-2016 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 Pfam PF01546 Peptidase family M20/M25/M40 72 479 1.7E-22 T 22-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 PIRSF PIRSF016599 1 485 4.7E-187 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 TIGRFAM TIGR01893 aa-his-dipept: Xaa-His dipeptidase 9 482 2.6E-168 T 22-04-2016 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 TOLA_RS02885 40356fd2792fd0066169b8cf29023a51 487 Pfam PF07687 Peptidase dimerisation domain 212 291 1.0E-4 T 22-04-2016 IPR011650 Peptidase M20, dimerisation domain TOLA_RS05150 1012f117459be15484900a3386230105 129 Pfam PF01219 Prokaryotic diacylglycerol kinase 21 121 2.1E-31 T 22-04-2016 IPR000829 Diacylglycerol kinase, prokaryotic GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 TOLA_RS05150 1012f117459be15484900a3386230105 129 PANTHER PTHR34299 1 129 8.4E-29 T 22-04-2016 TOLA_RS05150 1012f117459be15484900a3386230105 129 PANTHER PTHR34299:SF1 1 129 8.4E-29 T 22-04-2016 TOLA_RS05150 1012f117459be15484900a3386230105 129 Gene3D G3DSA:1.10.3830.10 12 125 2.4E-34 T 22-04-2016 TOLA_RS16130 2771e2ec3bd4ed08c177a3f625b8ec05 629 SUPERFAMILY SSF51905 97 261 1.57E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS16130 2771e2ec3bd4ed08c177a3f625b8ec05 629 SUPERFAMILY SSF51905 6 66 1.57E-50 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS16130 2771e2ec3bd4ed08c177a3f625b8ec05 629 Pfam PF13932 GidA associated domain 403 616 3.6E-71 T 22-04-2016 IPR026904 GidA associated domain 3 TOLA_RS16130 2771e2ec3bd4ed08c177a3f625b8ec05 629 Pfam PF01134 Glucose inhibited division protein A 8 398 5.6E-167 T 22-04-2016 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 TOLA_RS16130 2771e2ec3bd4ed08c177a3f625b8ec05 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 22-04-2016 IPR020595 MnmG-related, conserved site TOLA_RS16130 2771e2ec3bd4ed08c177a3f625b8ec05 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 624 42.194 T 22-04-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 TOLA_RS16130 2771e2ec3bd4ed08c177a3f625b8ec05 629 PANTHER PTHR11806 1 629 0.0 T 22-04-2016 TOLA_RS16130 2771e2ec3bd4ed08c177a3f625b8ec05 629 PANTHER PTHR11806:SF0 1 629 0.0 T 22-04-2016 TOLA_RS16130 2771e2ec3bd4ed08c177a3f625b8ec05 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 22-04-2016 IPR020595 MnmG-related, conserved site TOLA_RS16130 2771e2ec3bd4ed08c177a3f625b8ec05 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 622 3.3E-280 T 22-04-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 TOLA_RS16130 2771e2ec3bd4ed08c177a3f625b8ec05 629 SMART SM01228 546 617 1.1E-43 T 22-04-2016 TOLA_RS16130 2771e2ec3bd4ed08c177a3f625b8ec05 629 Gene3D G3DSA:3.50.50.60 6 233 3.7E-52 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS13870 9c2fe5e0002d9c34d8c31da489533a7b 348 PANTHER PTHR30473:SF1 2 348 1.1E-190 T 22-04-2016 TOLA_RS13870 9c2fe5e0002d9c34d8c31da489533a7b 348 SUPERFAMILY SSF52540 123 299 3.46E-41 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13870 9c2fe5e0002d9c34d8c31da489533a7b 348 Gene3D G3DSA:3.40.50.300 124 327 1.4E-87 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS13870 9c2fe5e0002d9c34d8c31da489533a7b 348 PANTHER PTHR30473 2 348 1.1E-190 T 22-04-2016 TOLA_RS13870 9c2fe5e0002d9c34d8c31da489533a7b 348 Pfam PF02562 PhoH-like protein 124 327 6.5E-95 T 22-04-2016 IPR003714 PhoH-like protein GO:0005524 TOLA_RS05770 08dd2c2c7b58397f54a7cb65653e7aa2 123 Pfam PF04138 GtrA-like protein 12 122 1.6E-17 T 22-04-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 TOLA_RS03480 62b1f439036f860dc9934e3194ab0d24 319 Pfam PF01032 FecCD transport family 13 314 1.4E-65 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 TOLA_RS03480 62b1f439036f860dc9934e3194ab0d24 319 PANTHER PTHR30472:SF27 1 319 2.4E-140 T 22-04-2016 TOLA_RS03480 62b1f439036f860dc9934e3194ab0d24 319 PANTHER PTHR30472 1 319 2.4E-140 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 TOLA_RS03480 62b1f439036f860dc9934e3194ab0d24 319 Gene3D G3DSA:1.10.3470.10 4 316 2.2E-67 T 22-04-2016 IPR029022 ABC transporter, BtuC-like TOLA_RS03480 62b1f439036f860dc9934e3194ab0d24 319 SUPERFAMILY SSF81345 4 314 5.75E-64 T 22-04-2016 IPR029022 ABC transporter, BtuC-like TOLA_RS14795 38994d79aba4e9fa78d6a2904312c0b9 252 PANTHER PTHR33362 2 250 3.0E-106 T 22-04-2016 TOLA_RS14795 38994d79aba4e9fa78d6a2904312c0b9 252 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 2 242 2.8E-63 T 22-04-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TOLA_RS14795 38994d79aba4e9fa78d6a2904312c0b9 252 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 2 247 4.2E-81 T 22-04-2016 IPR004681 TRAP transporter permease protein GO:0016021 TOLA_RS14795 38994d79aba4e9fa78d6a2904312c0b9 252 PANTHER PTHR33362:SF2 2 250 3.0E-106 T 22-04-2016 TOLA_RS08740 2980f36a3c0c4322e5dea90397c8bf2f 292 PANTHER PTHR33608 33 292 1.1E-62 T 22-04-2016 TOLA_RS08740 2980f36a3c0c4322e5dea90397c8bf2f 292 PANTHER PTHR33608:SF6 33 292 1.1E-62 T 22-04-2016 TOLA_RS08740 2980f36a3c0c4322e5dea90397c8bf2f 292 SUPERFAMILY SSF53300 81 205 6.67E-6 T 22-04-2016 IPR002035 von Willebrand factor, type A TOLA_RS08740 2980f36a3c0c4322e5dea90397c8bf2f 292 Pfam PF01882 Protein of unknown function DUF58 45 129 1.1E-22 T 22-04-2016 IPR002881 Domain of unknown function DUF58 TOLA_RS02575 4a7a1643fb35627911268e90908390d0 111 PANTHER PTHR39586 1 107 5.2E-30 T 22-04-2016 TOLA_RS02575 4a7a1643fb35627911268e90908390d0 111 Pfam PF04287 tRNA pseudouridine synthase C 5 100 3.4E-33 T 22-04-2016 IPR023376 YqcC-like domain TOLA_RS02575 4a7a1643fb35627911268e90908390d0 111 Gene3D G3DSA:1.20.1440.40 2 102 2.3E-34 T 22-04-2016 IPR023376 YqcC-like domain TOLA_RS02575 4a7a1643fb35627911268e90908390d0 111 PIRSF PIRSF006257 1 106 1.3E-33 T 22-04-2016 IPR007384 Protein of unknown function UCP006257 TOLA_RS02575 4a7a1643fb35627911268e90908390d0 111 SUPERFAMILY SSF158452 2 105 7.45E-36 T 22-04-2016 IPR023376 YqcC-like domain TOLA_RS03765 cb9f65f0ebddd8e26e7cef54f7d67bf1 76 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 35 66 2.7E-7 T 22-04-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 TOLA_RS03765 cb9f65f0ebddd8e26e7cef54f7d67bf1 76 SUPERFAMILY SSF57716 36 70 3.85E-6 T 22-04-2016 TOLA_RS03765 cb9f65f0ebddd8e26e7cef54f7d67bf1 76 PANTHER PTHR38777:SF1 1 74 3.7E-12 T 22-04-2016 TOLA_RS03765 cb9f65f0ebddd8e26e7cef54f7d67bf1 76 PANTHER PTHR38777 1 74 3.7E-12 T 22-04-2016 TOLA_RS15450 efb143f790f51fe5f39bc05388f79f53 220 PANTHER PTHR11002:SF20 2 208 7.9E-117 T 22-04-2016 TOLA_RS15450 efb143f790f51fe5f39bc05388f79f53 220 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 42 49 - T 22-04-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TOLA_RS15450 efb143f790f51fe5f39bc05388f79f53 220 Pfam PF00484 Carbonic anhydrase 37 188 8.0E-54 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TOLA_RS15450 efb143f790f51fe5f39bc05388f79f53 220 SUPERFAMILY SSF53056 3 211 8.5E-77 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TOLA_RS15450 efb143f790f51fe5f39bc05388f79f53 220 SMART SM00947 30 193 2.2E-70 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TOLA_RS15450 efb143f790f51fe5f39bc05388f79f53 220 PANTHER PTHR11002 2 208 7.9E-117 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TOLA_RS15450 efb143f790f51fe5f39bc05388f79f53 220 Gene3D G3DSA:3.40.1050.10 4 204 1.1E-77 T 22-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TOLA_RS15450 efb143f790f51fe5f39bc05388f79f53 220 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 22-04-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TOLA_RS03085 9642ec09f6afcbd466fd60d1896cd0e0 144 SUPERFAMILY SSF54637 3 135 4.54E-28 T 22-04-2016 IPR029069 HotDog domain TOLA_RS03085 9642ec09f6afcbd466fd60d1896cd0e0 144 PANTHER PTHR12418:SF33 1 144 3.2E-55 T 22-04-2016 TOLA_RS03085 9642ec09f6afcbd466fd60d1896cd0e0 144 Gene3D G3DSA:3.10.129.10 1 139 6.9E-49 T 22-04-2016 IPR029069 HotDog domain TOLA_RS03085 9642ec09f6afcbd466fd60d1896cd0e0 144 Pfam PF03061 Thioesterase superfamily 49 125 9.1E-13 T 22-04-2016 IPR006683 Thioesterase domain TOLA_RS03085 9642ec09f6afcbd466fd60d1896cd0e0 144 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 133 1.2E-40 T 22-04-2016 IPR003736 Phenylacetic acid degradation-related domain TOLA_RS03085 9642ec09f6afcbd466fd60d1896cd0e0 144 PANTHER PTHR12418 1 144 3.2E-55 T 22-04-2016 TOLA_RS11685 ec069e1baa5c77d06791bd5c94c4a9bd 288 Gene3D G3DSA:3.40.50.620 3 176 4.7E-79 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS11685 ec069e1baa5c77d06791bd5c94c4a9bd 288 SUPERFAMILY SSF52374 3 282 1.07E-103 T 22-04-2016 TOLA_RS11685 ec069e1baa5c77d06791bd5c94c4a9bd 288 PANTHER PTHR21299 3 288 6.7E-132 T 22-04-2016 TOLA_RS11685 ec069e1baa5c77d06791bd5c94c4a9bd 288 PANTHER PTHR21299:SF1 3 288 6.7E-132 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 TOLA_RS11685 ec069e1baa5c77d06791bd5c94c4a9bd 288 Pfam PF02569 Pantoate-beta-alanine ligase 3 279 1.9E-100 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 TOLA_RS11685 ec069e1baa5c77d06791bd5c94c4a9bd 288 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 23 67 3.8E-10 T 22-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TOLA_RS11685 ec069e1baa5c77d06791bd5c94c4a9bd 288 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 282 1.1E-106 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 TOLA_RS11685 ec069e1baa5c77d06791bd5c94c4a9bd 288 Gene3D G3DSA:3.30.1300.10 181 283 4.5E-25 T 22-04-2016 TOLA_RS11685 ec069e1baa5c77d06791bd5c94c4a9bd 288 Hamap MF_00158 Pantothenate synthetase [panC]. 2 281 39.138 T 22-04-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 TOLA_RS00185 3325c683e37357fb5b227430a5a0f17b 416 Pfam PF04932 O-Antigen ligase 182 337 9.5E-21 T 22-04-2016 IPR007016 O-antigen ligase-related TOLA_RS00185 3325c683e37357fb5b227430a5a0f17b 416 PANTHER PTHR37422 6 407 4.5E-39 T 22-04-2016 TOLA_RS00185 3325c683e37357fb5b227430a5a0f17b 416 PANTHER PTHR37422:SF2 6 407 4.5E-39 T 22-04-2016 TOLA_RS15445 2604bcd5bfb49f3172b17361a06f50b1 45 Pfam PF08085 Entericidin EcnA/B family 18 38 2.4E-10 T 22-04-2016 IPR012556 Entericidin A/B GO:0009636|GO:0016020 TOLA_RS02000 7627387a667b5c03290141cdd6cafe9e 158 SUPERFAMILY SSF102114 23 109 2.35E-9 T 22-04-2016 TOLA_RS02000 7627387a667b5c03290141cdd6cafe9e 158 ProSitePatterns PS01087 Radical activating enzymes signature. 14 35 - T 22-04-2016 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 TOLA_RS02000 7627387a667b5c03290141cdd6cafe9e 158 PIRSF PIRSF000368 1 158 6.7E-60 T 22-04-2016 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 KEGG: 00351+1.97.1.-|KEGG: 00361+1.97.1.-|KEGG: 00363+1.97.1.-|KEGG: 00625+1.97.1.- TOLA_RS02000 7627387a667b5c03290141cdd6cafe9e 158 PANTHER PTHR30352:SF2 1 155 8.7E-70 T 22-04-2016 TOLA_RS02000 7627387a667b5c03290141cdd6cafe9e 158 Pfam PF13353 4Fe-4S single cluster domain 12 151 7.1E-54 T 22-04-2016 TOLA_RS02000 7627387a667b5c03290141cdd6cafe9e 158 Gene3D G3DSA:3.20.20.70 22 114 4.2E-10 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS02000 7627387a667b5c03290141cdd6cafe9e 158 PANTHER PTHR30352 1 155 8.7E-70 T 22-04-2016 TOLA_RS02000 7627387a667b5c03290141cdd6cafe9e 158 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 3 153 7.3E-61 T 22-04-2016 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 KEGG: 00351+1.97.1.-|KEGG: 00361+1.97.1.-|KEGG: 00363+1.97.1.-|KEGG: 00625+1.97.1.- TOLA_RS14970 9eae49453779d14233b73500bede7d10 169 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 8.0E-50 T 22-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TOLA_RS14970 9eae49453779d14233b73500bede7d10 169 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 121 140 8.0E-50 T 22-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TOLA_RS14970 9eae49453779d14233b73500bede7d10 169 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 8.0E-50 T 22-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TOLA_RS14970 9eae49453779d14233b73500bede7d10 169 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 77 95 8.0E-50 T 22-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TOLA_RS14970 9eae49453779d14233b73500bede7d10 169 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 8.0E-50 T 22-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TOLA_RS14970 9eae49453779d14233b73500bede7d10 169 PIRSF PIRSF006160 1 162 1.7E-64 T 22-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TOLA_RS14970 9eae49453779d14233b73500bede7d10 169 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 159 35.272 T 22-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TOLA_RS14970 9eae49453779d14233b73500bede7d10 169 Gene3D G3DSA:3.30.1360.80 1 167 1.1E-72 T 22-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TOLA_RS14970 9eae49453779d14233b73500bede7d10 169 SUPERFAMILY SSF63411 4 162 4.49E-65 T 22-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TOLA_RS14970 9eae49453779d14233b73500bede7d10 169 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 153 3.1E-60 T 22-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TOLA_RS14970 9eae49453779d14233b73500bede7d10 169 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 154 2.0E-68 T 22-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TOLA_RS14970 9eae49453779d14233b73500bede7d10 169 PANTHER PTHR35799 2 169 4.7E-99 T 22-04-2016 TOLA_RS06635 eef5ae3b2b5703b27dfc22583957f553 150 PANTHER PTHR23091 1 146 1.3E-13 T 22-04-2016 TOLA_RS06635 eef5ae3b2b5703b27dfc22583957f553 150 SUPERFAMILY SSF55729 4 124 2.62E-18 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS06635 eef5ae3b2b5703b27dfc22583957f553 150 Pfam PF13508 Acetyltransferase (GNAT) domain 40 124 7.0E-11 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS06635 eef5ae3b2b5703b27dfc22583957f553 150 Gene3D G3DSA:3.40.630.30 14 135 6.6E-30 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS16305 0b6b3f822fefd26e4707062f7d0c6458 1145 PANTHER PTHR38812:SF1 19 1122 1.0E-25 T 22-04-2016 TOLA_RS16305 0b6b3f822fefd26e4707062f7d0c6458 1145 PANTHER PTHR38812 19 1122 1.0E-25 T 22-04-2016 TOLA_RS16305 0b6b3f822fefd26e4707062f7d0c6458 1145 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 277 350 1.4E-17 T 22-04-2016 IPR013491 Caudovirus, tape measure, N-terminal TOLA_RS03970 8df298f2fa473394db00e88f62370f69 135 Pfam PF06146 Phosphate-starvation-inducible E 46 111 4.3E-17 T 22-04-2016 IPR020948 Phosphate-starvation-induced PsiE-like TOLA_RS03970 8df298f2fa473394db00e88f62370f69 135 PIRSF PIRSF029598 1 130 1.1E-32 T 22-04-2016 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 TOLA_RS03970 8df298f2fa473394db00e88f62370f69 135 PANTHER PTHR37819 1 134 1.6E-29 T 22-04-2016 TOLA_RS03970 8df298f2fa473394db00e88f62370f69 135 PANTHER PTHR37819:SF1 1 134 1.6E-29 T 22-04-2016 TOLA_RS07155 ea28d947848001228feef86dc6ea52d8 296 SUPERFAMILY SSF53850 91 293 1.47E-33 T 22-04-2016 TOLA_RS07155 ea28d947848001228feef86dc6ea52d8 296 Gene3D G3DSA:3.40.190.10 95 194 1.2E-18 T 22-04-2016 TOLA_RS07155 ea28d947848001228feef86dc6ea52d8 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 4.7E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07155 ea28d947848001228feef86dc6ea52d8 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 4.7E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07155 ea28d947848001228feef86dc6ea52d8 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 4.7E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07155 ea28d947848001228feef86dc6ea52d8 296 SUPERFAMILY SSF46785 7 86 6.14E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07155 ea28d947848001228feef86dc6ea52d8 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 8.8E-20 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS07155 ea28d947848001228feef86dc6ea52d8 296 Gene3D G3DSA:1.10.10.10 6 84 8.0E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07155 ea28d947848001228feef86dc6ea52d8 296 Pfam PF03466 LysR substrate binding domain 91 289 4.9E-32 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS07155 ea28d947848001228feef86dc6ea52d8 296 PANTHER PTHR30537 1 295 4.4E-85 T 22-04-2016 TOLA_RS15980 d3b4e4611bc9c5d8cbd605803b320ca7 83 SMART SM00530 12 67 4.1E-8 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS15980 d3b4e4611bc9c5d8cbd605803b320ca7 83 SUPERFAMILY SSF47413 5 71 7.68E-18 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS15980 d3b4e4611bc9c5d8cbd605803b320ca7 83 Gene3D G3DSA:1.10.260.40 8 70 8.8E-13 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS15980 d3b4e4611bc9c5d8cbd605803b320ca7 83 Pfam PF01381 Helix-turn-helix 13 64 1.3E-10 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS02835 9c3fe514bc562fe2c1d1f1dc08dd21ec 356 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 354 3.3E-127 T 22-04-2016 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 TOLA_RS02835 9c3fe514bc562fe2c1d1f1dc08dd21ec 356 PANTHER PTHR33529 1 355 1.1E-121 T 22-04-2016 TOLA_RS02835 9c3fe514bc562fe2c1d1f1dc08dd21ec 356 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 354 1.9E-69 T 22-04-2016 IPR005495 Permease LptG/LptF-related GO:0016021 TOLA_RS02835 9c3fe514bc562fe2c1d1f1dc08dd21ec 356 PANTHER PTHR33529:SF1 1 355 1.1E-121 T 22-04-2016 TOLA_RS06640 716015ba6e6457f5370683db334e7074 316 PANTHER PTHR11079 41 316 9.7E-92 T 22-04-2016 TOLA_RS06640 716015ba6e6457f5370683db334e7074 316 SUPERFAMILY SSF55120 100 311 5.96E-47 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS06640 716015ba6e6457f5370683db334e7074 316 PANTHER PTHR11079:SF61 41 316 9.7E-92 T 22-04-2016 TOLA_RS06640 716015ba6e6457f5370683db334e7074 316 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 154 168 - T 22-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS06640 716015ba6e6457f5370683db334e7074 316 Pfam PF00849 RNA pseudouridylate synthase 115 262 2.9E-25 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS15935 91009e4adf23bf4ea8100a7a9293158e 469 Pfam PF00232 Glycosyl hydrolase family 1 7 467 6.4E-148 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15935 91009e4adf23bf4ea8100a7a9293158e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 366 374 7.0E-14 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15935 91009e4adf23bf4ea8100a7a9293158e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 408 425 7.0E-14 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15935 91009e4adf23bf4ea8100a7a9293158e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 432 444 7.0E-14 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15935 91009e4adf23bf4ea8100a7a9293158e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 289 303 7.0E-14 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15935 91009e4adf23bf4ea8100a7a9293158e 469 PRINTS PR00131 Glycosyl hydrolase family 1 signature 387 398 7.0E-14 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS15935 91009e4adf23bf4ea8100a7a9293158e 469 PANTHER PTHR10353:SF60 9 468 1.2E-186 T 22-04-2016 TOLA_RS15935 91009e4adf23bf4ea8100a7a9293158e 469 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 13 27 - T 22-04-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TOLA_RS15935 91009e4adf23bf4ea8100a7a9293158e 469 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 366 374 - T 22-04-2016 IPR018120 Glycoside hydrolase family 1, active site TOLA_RS15935 91009e4adf23bf4ea8100a7a9293158e 469 Gene3D G3DSA:3.20.20.80 7 468 1.9E-150 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS15935 91009e4adf23bf4ea8100a7a9293158e 469 SUPERFAMILY SSF51445 7 467 1.93E-159 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS15935 91009e4adf23bf4ea8100a7a9293158e 469 PANTHER PTHR10353 9 468 1.2E-186 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 SUPERFAMILY SSF51735 1 249 2.75E-78 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 8.5E-65 T 22-04-2016 TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 Gene3D G3DSA:3.40.50.720 2 249 1.0E-81 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PANTHER PTHR24322:SF330 157 189 1.8E-48 T 22-04-2016 TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PANTHER PTHR24322:SF330 12 141 1.8E-48 T 22-04-2016 TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.1E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.1E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.1E-9 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PANTHER PTHR24322 157 189 1.8E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PANTHER PTHR24322 12 141 1.8E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.2E-44 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.2E-44 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.2E-44 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.2E-44 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.2E-44 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.2E-44 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12575 241450cff2050b2d1c0daea5f5d3c445 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TOLA_RS14505 762136384a02240f594de4e0c2bba673 323 Gene3D G3DSA:1.10.530.10 204 319 1.9E-54 T 22-04-2016 TOLA_RS14505 762136384a02240f594de4e0c2bba673 323 Gene3D G3DSA:1.10.530.10 67 122 1.9E-54 T 22-04-2016 TOLA_RS14505 762136384a02240f594de4e0c2bba673 323 PANTHER PTHR30163 4 320 1.1E-113 T 22-04-2016 IPR011757 Lytic transglycosylase MltB TOLA_RS14505 762136384a02240f594de4e0c2bba673 323 Pfam PF13406 Transglycosylase SLT domain 25 314 6.6E-94 T 22-04-2016 IPR031304 Transglycosylase SLT domain 2 TOLA_RS14505 762136384a02240f594de4e0c2bba673 323 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 31 316 3.0E-104 T 22-04-2016 IPR011757 Lytic transglycosylase MltB TOLA_RS14505 762136384a02240f594de4e0c2bba673 323 SUPERFAMILY SSF53955 10 319 3.75E-82 T 22-04-2016 IPR023346 Lysozyme-like domain TOLA_RS14505 762136384a02240f594de4e0c2bba673 323 PANTHER PTHR30163:SF0 4 320 1.1E-113 T 22-04-2016 TOLA_RS00720 387895c01b12af43492f301d21408b8f 415 PANTHER PTHR30482 57 413 1.6E-172 T 22-04-2016 TOLA_RS00720 387895c01b12af43492f301d21408b8f 415 PANTHER PTHR30482:SF9 57 413 1.6E-172 T 22-04-2016 TOLA_RS00720 387895c01b12af43492f301d21408b8f 415 Pfam PF11862 Domain of unknown function (DUF3382) 2 99 2.2E-16 T 22-04-2016 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal TOLA_RS00720 387895c01b12af43492f301d21408b8f 415 Pfam PF02653 Branched-chain amino acid transport system / permease component 111 396 4.2E-55 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS01750 ab60f4cac1aabdac9252e0abf125e50c 543 PANTHER PTHR10566:SF79 5 467 4.7E-265 T 22-04-2016 TOLA_RS01750 ab60f4cac1aabdac9252e0abf125e50c 543 SUPERFAMILY SSF56112 94 158 3.02E-46 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS01750 ab60f4cac1aabdac9252e0abf125e50c 543 SUPERFAMILY SSF56112 192 435 3.02E-46 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS01750 ab60f4cac1aabdac9252e0abf125e50c 543 PANTHER PTHR10566 5 467 4.7E-265 T 22-04-2016 TOLA_RS01750 ab60f4cac1aabdac9252e0abf125e50c 543 Pfam PF03109 ABC1 family 112 230 2.1E-34 T 22-04-2016 IPR004147 UbiB domain TOLA_RS01750 ab60f4cac1aabdac9252e0abf125e50c 543 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 7 444 4.6E-175 T 22-04-2016 IPR010232 Probable protein kinase UbiB GO:0006744 UniPathway: UPA00232 TOLA_RS01750 ab60f4cac1aabdac9252e0abf125e50c 543 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 3 537 54.814 T 22-04-2016 IPR010232 Probable protein kinase UbiB GO:0006744 UniPathway: UPA00232 TOLA_RS08780 53520aa2d2de3bd29d0215e5b4ad895d 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 4.2E-51 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 TOLA_RS08780 53520aa2d2de3bd29d0215e5b4ad895d 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.737 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 TOLA_RS08780 53520aa2d2de3bd29d0215e5b4ad895d 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.2E-42 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 TOLA_RS08780 53520aa2d2de3bd29d0215e5b4ad895d 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.2E-42 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 TOLA_RS08780 53520aa2d2de3bd29d0215e5b4ad895d 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.2E-42 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 TOLA_RS08780 53520aa2d2de3bd29d0215e5b4ad895d 118 PANTHER PTHR10986 2 117 8.3E-67 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 TOLA_RS08780 53520aa2d2de3bd29d0215e5b4ad895d 118 Gene3D G3DSA:1.10.1900.20 55 117 2.6E-31 T 22-04-2016 TOLA_RS08780 53520aa2d2de3bd29d0215e5b4ad895d 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 TOLA_RS08780 53520aa2d2de3bd29d0215e5b4ad895d 118 Pfam PF00453 Ribosomal protein L20 3 109 1.6E-49 T 22-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 TOLA_RS08780 53520aa2d2de3bd29d0215e5b4ad895d 118 PANTHER PTHR10986:SF12 2 117 8.3E-67 T 22-04-2016 TOLA_RS08780 53520aa2d2de3bd29d0215e5b4ad895d 118 SUPERFAMILY SSF74731 2 117 1.44E-50 T 22-04-2016 TOLA_RS08780 53520aa2d2de3bd29d0215e5b4ad895d 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 2.0E-13 T 22-04-2016 TOLA_RS10575 762de3a1484c8f29da33191584359c07 456 Pfam PF07690 Major Facilitator Superfamily 20 354 2.2E-40 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS10575 762de3a1484c8f29da33191584359c07 456 PANTHER PTHR23510:SF6 1 400 3.6E-202 T 22-04-2016 TOLA_RS10575 762de3a1484c8f29da33191584359c07 456 Gene3D G3DSA:1.20.1250.20 212 393 7.0E-22 T 22-04-2016 TOLA_RS10575 762de3a1484c8f29da33191584359c07 456 Gene3D G3DSA:1.20.1250.20 12 195 2.0E-33 T 22-04-2016 TOLA_RS10575 762de3a1484c8f29da33191584359c07 456 SUPERFAMILY SSF103473 3 392 5.62E-61 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS10575 762de3a1484c8f29da33191584359c07 456 PANTHER PTHR23510 1 400 3.6E-202 T 22-04-2016 TOLA_RS01670 fc15a870e4b9183e2eca5419781a0353 280 SUPERFAMILY SSF56281 3 105 7.08E-34 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS01670 fc15a870e4b9183e2eca5419781a0353 280 SUPERFAMILY SSF56281 139 264 7.08E-34 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS01670 fc15a870e4b9183e2eca5419781a0353 280 Pfam PF00753 Metallo-beta-lactamase superfamily 31 159 1.5E-9 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS01670 fc15a870e4b9183e2eca5419781a0353 280 SMART SM00849 23 249 0.0013 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS01670 fc15a870e4b9183e2eca5419781a0353 280 PANTHER PTHR13754:SF13 4 277 5.4E-60 T 22-04-2016 TOLA_RS01670 fc15a870e4b9183e2eca5419781a0353 280 PANTHER PTHR13754 4 277 5.4E-60 T 22-04-2016 TOLA_RS01670 fc15a870e4b9183e2eca5419781a0353 280 Gene3D G3DSA:3.60.15.10 5 114 2.1E-32 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS01670 fc15a870e4b9183e2eca5419781a0353 280 Gene3D G3DSA:3.60.15.10 148 268 2.1E-32 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS11665 33a10ee3e99941f0ae827be36b4a52de 373 Gene3D G3DSA:2.40.50.100 63 96 3.0E-19 T 22-04-2016 TOLA_RS11665 33a10ee3e99941f0ae827be36b4a52de 373 Gene3D G3DSA:2.40.50.100 171 203 3.0E-19 T 22-04-2016 TOLA_RS11665 33a10ee3e99941f0ae827be36b4a52de 373 PANTHER PTHR30469:SF0 1 373 1.5E-80 T 22-04-2016 TOLA_RS11665 33a10ee3e99941f0ae827be36b4a52de 373 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 364 5.5E-82 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 TOLA_RS11665 33a10ee3e99941f0ae827be36b4a52de 373 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 54 284 5.4E-15 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TOLA_RS11665 33a10ee3e99941f0ae827be36b4a52de 373 PANTHER PTHR30469 1 373 1.5E-80 T 22-04-2016 TOLA_RS11665 33a10ee3e99941f0ae827be36b4a52de 373 SUPERFAMILY SSF111369 53 288 4.84E-54 T 22-04-2016 TOLA_RS08630 8f9a6792a9fa195f37e2dabf0d507415 467 SUPERFAMILY SSF53720 33 458 2.36E-56 T 22-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 TOLA_RS08630 8f9a6792a9fa195f37e2dabf0d507415 467 PANTHER PTHR11699:SF68 31 421 6.5E-157 T 22-04-2016 TOLA_RS08630 8f9a6792a9fa195f37e2dabf0d507415 467 Gene3D G3DSA:3.40.605.10 36 253 6.0E-22 T 22-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 TOLA_RS08630 8f9a6792a9fa195f37e2dabf0d507415 467 PIRSF PIRSF036410 1 467 1.3E-208 T 22-04-2016 IPR012408 Acetaldehyde/propionaldehyde dehydrogenase, EutE/PduP-related UniPathway: UPA00560 TOLA_RS08630 8f9a6792a9fa195f37e2dabf0d507415 467 Pfam PF00171 Aldehyde dehydrogenase family 20 421 3.2E-25 T 22-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 TOLA_RS08630 8f9a6792a9fa195f37e2dabf0d507415 467 Gene3D G3DSA:3.40.309.10 254 427 1.4E-22 T 22-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 TOLA_RS08630 8f9a6792a9fa195f37e2dabf0d507415 467 PANTHER PTHR11699 31 421 6.5E-157 T 22-04-2016 TOLA_RS12835 75b8ed3d59debac1f9ca821cf8c69b9a 138 PANTHER PTHR11078 1 134 7.5E-49 T 22-04-2016 IPR011605 NusB antitermination factor GO:0006353 TOLA_RS12835 75b8ed3d59debac1f9ca821cf8c69b9a 138 SUPERFAMILY SSF48013 4 134 2.49E-42 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TOLA_RS12835 75b8ed3d59debac1f9ca821cf8c69b9a 138 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 5 133 3.8E-45 T 22-04-2016 IPR011605 NusB antitermination factor GO:0006353 TOLA_RS12835 75b8ed3d59debac1f9ca821cf8c69b9a 138 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 4 135 23.775 T 22-04-2016 IPR011605 NusB antitermination factor GO:0006353 TOLA_RS12835 75b8ed3d59debac1f9ca821cf8c69b9a 138 Pfam PF01029 NusB family 7 132 5.9E-36 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TOLA_RS12835 75b8ed3d59debac1f9ca821cf8c69b9a 138 Gene3D G3DSA:1.10.940.10 5 134 1.5E-43 T 22-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TOLA_RS07175 ca166cd095d02b851b9ffadae46368c3 247 PANTHER PTHR11228:SF26 1 204 4.3E-58 T 22-04-2016 TOLA_RS07175 ca166cd095d02b851b9ffadae46368c3 247 Gene3D G3DSA:3.20.20.70 27 191 5.4E-5 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS07175 ca166cd095d02b851b9ffadae46368c3 247 Pfam PF04055 Radical SAM superfamily 22 185 1.7E-13 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS07175 ca166cd095d02b851b9ffadae46368c3 247 SUPERFAMILY SSF102114 21 193 2.88E-10 T 22-04-2016 TOLA_RS07175 ca166cd095d02b851b9ffadae46368c3 247 SMART SM00729 18 225 3.9E-4 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TOLA_RS07175 ca166cd095d02b851b9ffadae46368c3 247 PANTHER PTHR11228 1 204 4.3E-58 T 22-04-2016 TOLA_RS15175 783aac555efbcbd95930657b4d66f968 298 Gene3D G3DSA:3.40.190.10 201 256 5.8E-4 T 22-04-2016 TOLA_RS15175 783aac555efbcbd95930657b4d66f968 298 Gene3D G3DSA:3.40.190.10 92 200 1.5E-4 T 22-04-2016 TOLA_RS15175 783aac555efbcbd95930657b4d66f968 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 5.0E-16 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS15175 783aac555efbcbd95930657b4d66f968 298 SUPERFAMILY SSF46785 3 83 5.18E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15175 783aac555efbcbd95930657b4d66f968 298 SUPERFAMILY SSF53850 92 287 1.86E-25 T 22-04-2016 TOLA_RS15175 783aac555efbcbd95930657b4d66f968 298 Gene3D G3DSA:1.10.10.10 4 82 5.6E-21 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15175 783aac555efbcbd95930657b4d66f968 298 Pfam PF03466 LysR substrate binding domain 90 287 6.1E-16 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS15175 783aac555efbcbd95930657b4d66f968 298 PANTHER PTHR30293 2 298 7.8E-181 T 22-04-2016 TOLA_RS15175 783aac555efbcbd95930657b4d66f968 298 PANTHER PTHR30293:SF2 2 298 7.8E-181 T 22-04-2016 TOLA_RS16300 ece23bd1539b2a9c17556c160172a592 141 Pfam PF11743 Protein of unknown function (DUF3301) 4 94 1.2E-19 T 22-04-2016 IPR021732 Protein of unknown function DUF3301 TOLA_RS08990 ed7b402223d2ecdeca00d1ed8b06a9e3 371 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 339 3.2E-83 T 22-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 TOLA_RS08990 ed7b402223d2ecdeca00d1ed8b06a9e3 371 Gene3D G3DSA:3.20.20.70 2 365 1.0E-125 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS08990 ed7b402223d2ecdeca00d1ed8b06a9e3 371 PANTHER PTHR22893 1 366 9.1E-158 T 22-04-2016 TOLA_RS08990 ed7b402223d2ecdeca00d1ed8b06a9e3 371 SUPERFAMILY SSF51395 1 366 1.21E-114 T 22-04-2016 TOLA_RS08990 ed7b402223d2ecdeca00d1ed8b06a9e3 371 PANTHER PTHR22893:SF14 1 366 9.1E-158 T 22-04-2016 TOLA_RS08935 47ee9ec6e77f80f158d418d42fb024f2 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 12 152 3.0E-39 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS08935 47ee9ec6e77f80f158d418d42fb024f2 170 SMART SM00852 14 158 9.8E-29 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS08935 47ee9ec6e77f80f158d418d42fb024f2 170 PANTHER PTHR10192 4 170 5.8E-95 T 22-04-2016 TOLA_RS08935 47ee9ec6e77f80f158d418d42fb024f2 170 Gene3D G3DSA:3.40.980.10 7 167 4.8E-51 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS08935 47ee9ec6e77f80f158d418d42fb024f2 170 PIRSF PIRSF006443 1 166 2.5E-66 T 22-04-2016 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 UniPathway: UPA00344 TOLA_RS08935 47ee9ec6e77f80f158d418d42fb024f2 170 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 7 168 2.2E-87 T 22-04-2016 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 UniPathway: UPA00344 TOLA_RS08935 47ee9ec6e77f80f158d418d42fb024f2 170 SUPERFAMILY SSF53218 7 169 3.27E-48 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS08935 47ee9ec6e77f80f158d418d42fb024f2 170 Pfam PF00994 Probable molybdopterin binding domain 14 155 3.0E-35 T 22-04-2016 IPR001453 MoaB/Mog domain TOLA_RS08935 47ee9ec6e77f80f158d418d42fb024f2 170 PANTHER PTHR10192:SF18 4 170 5.8E-95 T 22-04-2016 TOLA_RS13985 51199ad374a6a717cce029882e2b8702 204 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 1 204 37.059 T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TOLA_RS13985 51199ad374a6a717cce029882e2b8702 204 Gene3D G3DSA:3.40.50.150 8 201 1.8E-59 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS13985 51199ad374a6a717cce029882e2b8702 204 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 5 203 3.3E-75 T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TOLA_RS13985 51199ad374a6a717cce029882e2b8702 204 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 126 141 - T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TOLA_RS13985 51199ad374a6a717cce029882e2b8702 204 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 5 202 8.6E-66 T 22-04-2016 TOLA_RS13985 51199ad374a6a717cce029882e2b8702 204 SUPERFAMILY SSF53335 10 201 6.54E-42 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS13985 51199ad374a6a717cce029882e2b8702 204 PANTHER PTHR11579 5 199 6.6E-80 T 22-04-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TOLA_RS07760 5295257f55c8eff6d75fc4c5a3b1c170 398 Gene3D G3DSA:3.40.640.10 45 315 1.8E-102 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS07760 5295257f55c8eff6d75fc4c5a3b1c170 398 PANTHER PTHR11879 1 398 1.0E-219 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 TOLA_RS07760 5295257f55c8eff6d75fc4c5a3b1c170 398 SUPERFAMILY SSF53383 1 396 8.48E-118 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS07760 5295257f55c8eff6d75fc4c5a3b1c170 398 PRINTS PR00799 Aspartate aminotransferase signature 273 298 2.6E-38 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 TOLA_RS07760 5295257f55c8eff6d75fc4c5a3b1c170 398 PRINTS PR00799 Aspartate aminotransferase signature 206 218 2.6E-38 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 TOLA_RS07760 5295257f55c8eff6d75fc4c5a3b1c170 398 PRINTS PR00799 Aspartate aminotransferase signature 341 359 2.6E-38 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 TOLA_RS07760 5295257f55c8eff6d75fc4c5a3b1c170 398 PRINTS PR00799 Aspartate aminotransferase signature 175 194 2.6E-38 T 22-04-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 TOLA_RS07760 5295257f55c8eff6d75fc4c5a3b1c170 398 Pfam PF00155 Aminotransferase class I and II 27 391 5.7E-78 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TOLA_RS07760 5295257f55c8eff6d75fc4c5a3b1c170 398 PANTHER PTHR11879:SF7 1 398 1.0E-219 T 22-04-2016 TOLA_RS15330 0ea97769fa2c6ddd68035b453bbac3f4 340 SUPERFAMILY SSF47413 1 60 1.5E-18 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS15330 0ea97769fa2c6ddd68035b453bbac3f4 340 Gene3D G3DSA:1.10.260.40 2 57 1.7E-27 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS15330 0ea97769fa2c6ddd68035b453bbac3f4 340 Gene3D G3DSA:3.40.50.2300 168 328 1.6E-53 T 22-04-2016 TOLA_RS15330 0ea97769fa2c6ddd68035b453bbac3f4 340 PANTHER PTHR30146 1 338 5.5E-128 T 22-04-2016 TOLA_RS15330 0ea97769fa2c6ddd68035b453bbac3f4 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 8.9E-6 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS15330 0ea97769fa2c6ddd68035b453bbac3f4 340 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 8.9E-6 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS15330 0ea97769fa2c6ddd68035b453bbac3f4 340 SMART SM00354 1 71 5.3E-35 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS15330 0ea97769fa2c6ddd68035b453bbac3f4 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.6E-21 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS15330 0ea97769fa2c6ddd68035b453bbac3f4 340 PANTHER PTHR30146:SF48 1 338 5.5E-128 T 22-04-2016 TOLA_RS15330 0ea97769fa2c6ddd68035b453bbac3f4 340 Pfam PF13377 Periplasmic binding protein-like domain 169 328 1.1E-35 T 22-04-2016 TOLA_RS15330 0ea97769fa2c6ddd68035b453bbac3f4 340 Gene3D G3DSA:3.40.50.2300 58 167 3.4E-41 T 22-04-2016 TOLA_RS15330 0ea97769fa2c6ddd68035b453bbac3f4 340 SUPERFAMILY SSF53822 61 330 1.3E-77 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 Pfam PF01043 SecA preprotein cross-linking domain 232 358 3.0E-38 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 Gene3D G3DSA:1.10.3060.10 648 830 5.2E-60 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 Gene3D G3DSA:3.40.50.300 369 416 5.8E-125 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 Gene3D G3DSA:3.40.50.300 2 228 5.8E-125 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 SUPERFAMILY SSF52540 416 618 4.07E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 832 19.901 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 Gene3D G3DSA:3.40.50.300 417 619 1.3E-89 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 SUPERFAMILY SSF81886 620 840 3.53E-82 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 SUPERFAMILY SSF81886 883 895 3.53E-82 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 SUPERFAMILY SSF81767 227 368 6.67E-42 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 PRINTS PR00906 SecA protein signature 117 127 5.8E-73 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 PRINTS PR00906 SecA protein signature 170 190 5.8E-73 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 PRINTS PR00906 SecA protein signature 413 426 5.8E-73 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 PRINTS PR00906 SecA protein signature 101 115 5.8E-73 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 PRINTS PR00906 SecA protein signature 63 87 5.8E-73 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 PRINTS PR00906 SecA protein signature 339 361 5.8E-73 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 PRINTS PR00906 SecA protein signature 376 393 5.8E-73 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 PANTHER PTHR30612 1 520 0.0 T 22-04-2016 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 PANTHER PTHR30612 550 907 0.0 T 22-04-2016 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 SUPERFAMILY SSF52540 368 415 1.52E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 SUPERFAMILY SSF52540 5 228 1.52E-83 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 ProSitePatterns PS01312 SecA family signature. 500 515 - T 22-04-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 817 0.0 T 22-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 Pfam PF02810 SEC-C motif 887 905 1.8E-10 T 22-04-2016 IPR004027 SEC-C motif TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 Pfam PF07517 SecA DEAD-like domain 7 402 2.4E-131 T 22-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 Pfam PF07516 SecA Wing and Scaffold domain 617 829 6.5E-70 T 22-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 SMART SM00957 6 402 5.8E-303 T 22-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 Gene3D G3DSA:3.90.1440.10 230 368 3.0E-44 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 TOLA_RS02750 697d3eb94009e884267b06aebb190ab6 907 SMART SM00958 228 358 6.3E-81 T 22-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 TOLA_RS02920 1b63e907e962911214f0b6d6008a6493 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 4.3E-6 T 22-04-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS02920 1b63e907e962911214f0b6d6008a6493 187 Pfam PF00578 AhpC/TSA family 6 132 3.1E-36 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS02920 1b63e907e962911214f0b6d6008a6493 187 PIRSF PIRSF000239 1 187 1.4E-57 T 22-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 TOLA_RS02920 1b63e907e962911214f0b6d6008a6493 187 Gene3D G3DSA:3.40.30.10 4 184 1.3E-65 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS02920 1b63e907e962911214f0b6d6008a6493 187 SUPERFAMILY SSF52833 1 186 1.28E-59 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS02920 1b63e907e962911214f0b6d6008a6493 187 PANTHER PTHR10681 1 187 6.2E-96 T 22-04-2016 TOLA_RS02920 1b63e907e962911214f0b6d6008a6493 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 6.0E-104 T 22-04-2016 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS02920 1b63e907e962911214f0b6d6008a6493 187 PANTHER PTHR10681:SF121 1 187 6.2E-96 T 22-04-2016 TOLA_RS07435 31acd91cd01a54ae5f9e1ebdc193caab 251 SUPERFAMILY SSF51351 1 248 1.44E-88 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 TOLA_RS07435 31acd91cd01a54ae5f9e1ebdc193caab 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 38.962 T 22-04-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 TOLA_RS07435 31acd91cd01a54ae5f9e1ebdc193caab 251 PANTHER PTHR21139 1 250 1.1E-114 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 TOLA_RS07435 31acd91cd01a54ae5f9e1ebdc193caab 251 Gene3D G3DSA:3.20.20.70 1 250 7.8E-96 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS07435 31acd91cd01a54ae5f9e1ebdc193caab 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 239 7.7E-65 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 TOLA_RS07435 31acd91cd01a54ae5f9e1ebdc193caab 251 Pfam PF00121 Triosephosphate isomerase 5 246 6.4E-87 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 TOLA_RS07435 31acd91cd01a54ae5f9e1ebdc193caab 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 22-04-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 TOLA_RS09430 bab736f9d0c01ab6ed2157ff325cff85 251 PANTHER PTHR30292:SF0 1 251 6.3E-132 T 22-04-2016 TOLA_RS09430 bab736f9d0c01ab6ed2157ff325cff85 251 PANTHER PTHR30292 1 251 6.3E-132 T 22-04-2016 TOLA_RS09430 bab736f9d0c01ab6ed2157ff325cff85 251 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 47.339 T 22-04-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF TOLA_RS09430 bab736f9d0c01ab6ed2157ff325cff85 251 SUPERFAMILY SSF88713 3 250 1.48E-102 T 22-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TOLA_RS09430 bab736f9d0c01ab6ed2157ff325cff85 251 Pfam PF03746 LamB/YcsF family 4 241 1.2E-106 T 22-04-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 SUPERFAMILY SSF109604 345 491 9.94E-16 T 22-04-2016 TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 PANTHER PTHR30075 1 690 0.0 T 22-04-2016 TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 Pfam PF05746 DALR anticodon binding domain 582 682 1.6E-8 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 Gene3D G3DSA:1.10.730.10 582 678 1.0E-5 T 22-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 2.8E-35 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 394 413 2.8E-35 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 246 261 2.8E-35 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 7 20 2.8E-35 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 318 334 2.8E-35 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 3 688 25.892 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 1 689 5.7E-293 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 6 551 2.3E-207 T 22-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TOLA_RS00040 4e7be3224e00dfee9bdb0349e982f49d 690 SMART SM00836 585 685 0.0038 T 22-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TOLA_RS12850 4bc5e5dc284027ca9b6dac0564a8847c 219 PIRSF PIRSF000498 1 212 5.7E-76 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS12850 4bc5e5dc284027ca9b6dac0564a8847c 219 SUPERFAMILY SSF63380 1 88 5.27E-23 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TOLA_RS12850 4bc5e5dc284027ca9b6dac0564a8847c 219 SUPERFAMILY SSF63380 93 194 1.53E-31 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TOLA_RS12850 4bc5e5dc284027ca9b6dac0564a8847c 219 Pfam PF00677 Lumazine binding domain 100 184 7.1E-21 T 22-04-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS12850 4bc5e5dc284027ca9b6dac0564a8847c 219 Pfam PF00677 Lumazine binding domain 3 87 5.4E-19 T 22-04-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS12850 4bc5e5dc284027ca9b6dac0564a8847c 219 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 204 3.9E-65 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS12850 4bc5e5dc284027ca9b6dac0564a8847c 219 Gene3D G3DSA:2.40.30.20 105 194 4.5E-31 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS12850 4bc5e5dc284027ca9b6dac0564a8847c 219 Gene3D G3DSA:2.40.30.20 5 104 1.4E-28 T 22-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TOLA_RS12850 4bc5e5dc284027ca9b6dac0564a8847c 219 PANTHER PTHR21098 1 219 5.0E-103 T 22-04-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 PANTHER PTHR22912 1 321 9.9E-98 T 22-04-2016 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 Gene3D G3DSA:3.50.50.60 4 107 2.1E-19 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 SUPERFAMILY SSF51905 3 305 1.56E-36 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 282 6.8E-47 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 Gene3D G3DSA:3.50.50.60 108 297 2.9E-39 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 PANTHER PTHR22912:SF130 1 321 9.9E-98 T 22-04-2016 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 8.2E-15 T 22-04-2016 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 8.2E-15 T 22-04-2016 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 8.2E-15 T 22-04-2016 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 279 8.2E-15 T 22-04-2016 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 279 1.7E-18 T 22-04-2016 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.7E-18 T 22-04-2016 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.7E-18 T 22-04-2016 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.7E-18 T 22-04-2016 TOLA_RS09260 6ffa713c82c40000e8dfb4496a067a04 381 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.7E-18 T 22-04-2016 TOLA_RS16090 280f784844a45e5e0d956ca0d1451257 177 PANTHER PTHR11910 7 176 1.1E-53 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 TOLA_RS16090 280f784844a45e5e0d956ca0d1451257 177 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 137 156 - T 22-04-2016 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 TOLA_RS16090 280f784844a45e5e0d956ca0d1451257 177 PRINTS PR00125 ATP synthase delta subunit signature 150 168 1.4E-29 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 TOLA_RS16090 280f784844a45e5e0d956ca0d1451257 177 PRINTS PR00125 ATP synthase delta subunit signature 135 150 1.4E-29 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 TOLA_RS16090 280f784844a45e5e0d956ca0d1451257 177 PRINTS PR00125 ATP synthase delta subunit signature 85 99 1.4E-29 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 TOLA_RS16090 280f784844a45e5e0d956ca0d1451257 177 PRINTS PR00125 ATP synthase delta subunit signature 7 26 1.4E-29 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 TOLA_RS16090 280f784844a45e5e0d956ca0d1451257 177 PRINTS PR00125 ATP synthase delta subunit signature 74 85 1.4E-29 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 TOLA_RS16090 280f784844a45e5e0d956ca0d1451257 177 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 177 18.722 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 TOLA_RS16090 280f784844a45e5e0d956ca0d1451257 177 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 175 1.1E-52 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 TOLA_RS16090 280f784844a45e5e0d956ca0d1451257 177 SUPERFAMILY SSF47928 3 105 2.22E-25 T 22-04-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain TOLA_RS16090 280f784844a45e5e0d956ca0d1451257 177 Gene3D G3DSA:1.10.520.20 3 105 2.5E-33 T 22-04-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain TOLA_RS16090 280f784844a45e5e0d956ca0d1451257 177 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 175 1.2E-51 T 22-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 TOLA_RS07630 8a3a6e8d7081b315a41af8e9d731369b 310 SUPERFAMILY SSF53686 3 304 6.42E-70 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TOLA_RS07630 8a3a6e8d7081b315a41af8e9d731369b 310 Gene3D G3DSA:3.40.50.1100 20 91 2.0E-5 T 22-04-2016 TOLA_RS07630 8a3a6e8d7081b315a41af8e9d731369b 310 PANTHER PTHR10314 3 301 2.7E-136 T 22-04-2016 TOLA_RS07630 8a3a6e8d7081b315a41af8e9d731369b 310 PANTHER PTHR10314:SF85 3 301 2.7E-136 T 22-04-2016 TOLA_RS07630 8a3a6e8d7081b315a41af8e9d731369b 310 Gene3D G3DSA:3.40.50.1100 92 308 9.4E-61 T 22-04-2016 TOLA_RS07630 8a3a6e8d7081b315a41af8e9d731369b 310 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 5 289 1.2E-66 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 Gene3D G3DSA:3.30.200.20 202 270 7.7E-9 T 22-04-2016 TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 Pfam PF07714 Protein tyrosine kinase 208 386 2.1E-12 T 22-04-2016 IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain GO:0004672|GO:0006468 TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 SMART SM00364 36 55 1.3 T 22-04-2016 TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 SMART SM00364 104 123 180.0 T 22-04-2016 TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 SMART SM00364 59 78 180.0 T 22-04-2016 TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 SMART SM00364 127 146 73.0 T 22-04-2016 TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 SMART SM00364 150 169 590.0 T 22-04-2016 TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 214 240 - T 22-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 PANTHER PTHR23155 27 187 7.6E-57 T 22-04-2016 TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 Gene3D G3DSA:1.10.510.10 271 385 2.5E-11 T 22-04-2016 TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 Pfam PF13855 Leucine rich repeat 130 185 2.4E-6 T 22-04-2016 IPR001611 Leucine-rich repeat GO:0005515 TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 SUPERFAMILY SSF52058 13 189 1.31E-36 T 22-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 Gene3D G3DSA:3.80.10.10 23 191 1.3E-36 T 22-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 SUPERFAMILY SSF56112 203 445 1.64E-24 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 Pfam PF12799 Leucine Rich repeats (2 copies) 38 75 7.8E-8 T 22-04-2016 IPR025875 Leucine rich repeat 4 TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 SMART SM00369 35 58 15.0 T 22-04-2016 IPR003591 Leucine-rich repeat, typical subtype TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 SMART SM00369 59 82 19.0 T 22-04-2016 IPR003591 Leucine-rich repeat, typical subtype TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 SMART SM00369 105 127 19.0 T 22-04-2016 IPR003591 Leucine-rich repeat, typical subtype TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 SMART SM00369 128 150 18.0 T 22-04-2016 IPR003591 Leucine-rich repeat, typical subtype TOLA_RS11010 1cd89a9deb95dffa6866a249812e11e8 455 PANTHER PTHR23155:SF644 27 187 7.6E-57 T 22-04-2016 TOLA_RS00065 ea55de72c1cadcbde3edd1ccdf3c5533 175 SUPERFAMILY SSF53474 2 164 2.92E-28 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS00065 ea55de72c1cadcbde3edd1ccdf3c5533 175 Gene3D G3DSA:3.40.50.1820 1 164 3.9E-37 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS00065 ea55de72c1cadcbde3edd1ccdf3c5533 175 Pfam PF06821 Serine hydrolase 4 165 1.3E-48 T 22-04-2016 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 KEGG: 00231+3.-.-.-|KEGG: 00563+3.-.-.-|KEGG: 00983+3.-.-.- TOLA_RS09820 27917bd55cebf0359c0997b1ec336b1d 382 Gene3D G3DSA:1.20.1090.10 187 382 9.3E-47 T 22-04-2016 TOLA_RS09820 27917bd55cebf0359c0997b1ec336b1d 382 Gene3D G3DSA:3.40.50.1970 1 184 6.5E-57 T 22-04-2016 TOLA_RS09820 27917bd55cebf0359c0997b1ec336b1d 382 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 366 1.0E-92 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 TOLA_RS09820 27917bd55cebf0359c0997b1ec336b1d 382 PANTHER PTHR11496 1 382 1.3E-102 T 22-04-2016 TOLA_RS09820 27917bd55cebf0359c0997b1ec336b1d 382 SUPERFAMILY SSF56796 1 381 1.96E-104 T 22-04-2016 TOLA_RS12700 e292ab9fe7545fc24ffd649678bdef7c 347 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 338 5.7E-77 T 22-04-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 TOLA_RS12700 e292ab9fe7545fc24ffd649678bdef7c 347 Hamap MF_00596 GMP reductase [guaC]. 1 345 54.968 T 22-04-2016 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: REACT_1698 TOLA_RS12700 e292ab9fe7545fc24ffd649678bdef7c 347 SUPERFAMILY SSF51412 6 336 3.66E-98 T 22-04-2016 TOLA_RS12700 e292ab9fe7545fc24ffd649678bdef7c 347 PANTHER PTHR11911 1 163 1.3E-203 T 22-04-2016 TOLA_RS12700 e292ab9fe7545fc24ffd649678bdef7c 347 PANTHER PTHR11911 181 346 1.3E-203 T 22-04-2016 TOLA_RS12700 e292ab9fe7545fc24ffd649678bdef7c 347 TIGRFAM TIGR01305 GMP_reduct_1: guanosine monophosphate reductase 2 344 3.2E-188 T 22-04-2016 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: REACT_1698 TOLA_RS12700 e292ab9fe7545fc24ffd649678bdef7c 347 Gene3D G3DSA:3.20.20.70 2 343 2.2E-110 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS12700 e292ab9fe7545fc24ffd649678bdef7c 347 PANTHER PTHR11911:SF66 1 163 1.3E-203 T 22-04-2016 TOLA_RS12700 e292ab9fe7545fc24ffd649678bdef7c 347 PANTHER PTHR11911:SF66 181 346 1.3E-203 T 22-04-2016 TOLA_RS12700 e292ab9fe7545fc24ffd649678bdef7c 347 SMART SM01240 7 344 8.8E-135 T 22-04-2016 TOLA_RS12700 e292ab9fe7545fc24ffd649678bdef7c 347 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 176 188 - T 22-04-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Reactome: REACT_1698 TOLA_RS12700 e292ab9fe7545fc24ffd649678bdef7c 347 PIRSF PIRSF000235 1 347 2.6E-193 T 22-04-2016 IPR005993 GMP reductase GO:0003920|GO:0009117|GO:1902560 KEGG: 00230+1.7.1.7|Reactome: REACT_1698 TOLA_RS10775 b69c4df775fe29e8cfc1b6774b9b7d6c 374 Gene3D G3DSA:1.10.3720.10 155 370 3.8E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10775 b69c4df775fe29e8cfc1b6774b9b7d6c 374 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 73 4.0E-15 T 22-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TOLA_RS10775 b69c4df775fe29e8cfc1b6774b9b7d6c 374 PANTHER PTHR30465 18 128 3.3E-93 T 22-04-2016 TOLA_RS10775 b69c4df775fe29e8cfc1b6774b9b7d6c 374 PANTHER PTHR30465 148 374 3.3E-93 T 22-04-2016 TOLA_RS10775 b69c4df775fe29e8cfc1b6774b9b7d6c 374 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 183 370 7.2E-21 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10775 b69c4df775fe29e8cfc1b6774b9b7d6c 374 SUPERFAMILY SSF161098 160 356 4.06E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS10775 b69c4df775fe29e8cfc1b6774b9b7d6c 374 PANTHER PTHR30465:SF33 18 128 3.3E-93 T 22-04-2016 TOLA_RS10775 b69c4df775fe29e8cfc1b6774b9b7d6c 374 PANTHER PTHR30465:SF33 148 374 3.3E-93 T 22-04-2016 TOLA_RS06320 fc58f0f6d9d5a6897e8bc50f8c70c928 422 Gene3D G3DSA:3.40.190.10 152 351 4.2E-64 T 22-04-2016 TOLA_RS06320 fc58f0f6d9d5a6897e8bc50f8c70c928 422 Gene3D G3DSA:3.40.190.10 32 151 1.5E-17 T 22-04-2016 TOLA_RS06320 fc58f0f6d9d5a6897e8bc50f8c70c928 422 SUPERFAMILY SSF53850 24 395 2.17E-81 T 22-04-2016 TOLA_RS06320 fc58f0f6d9d5a6897e8bc50f8c70c928 422 Pfam PF13416 Bacterial extracellular solute-binding protein 44 355 7.8E-33 T 22-04-2016 TOLA_RS06320 fc58f0f6d9d5a6897e8bc50f8c70c928 422 PANTHER PTHR30061 44 416 8.6E-60 T 22-04-2016 TOLA_RS07395 8e075e1ff5463f3df337f8033733bcf4 193 Pfam PF02508 Rnf-Nqr subunit, membrane protein 5 191 1.3E-60 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 TOLA_RS07395 8e075e1ff5463f3df337f8033733bcf4 193 PANTHER PTHR30335 2 193 5.0E-116 T 22-04-2016 TOLA_RS07395 8e075e1ff5463f3df337f8033733bcf4 193 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 3 191 2.7E-81 T 22-04-2016 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 TOLA_RS07395 8e075e1ff5463f3df337f8033733bcf4 193 Hamap MF_00459 Electron transport complex subunit RsxA [rsxA]. 2 191 25.438 T 22-04-2016 IPR011293 Electron transport complex, subunit RnfA/RsxA GO:0022900 TOLA_RS07395 8e075e1ff5463f3df337f8033733bcf4 193 PIRSF PIRSF006102 1 193 4.4E-60 T 22-04-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 TOLA_RS07395 8e075e1ff5463f3df337f8033733bcf4 193 PANTHER PTHR30335:SF0 2 193 5.0E-116 T 22-04-2016 TOLA_RS12430 f308e011f8c8223ad93a77a2251730e8 144 TIGRFAM TIGR03751 conj_TIGR03751: conjugative transfer region lipoprotein, TIGR03751 family 13 141 1.8E-52 T 22-04-2016 IPR022262 Lipoprotein, putative TOLA_RS16205 7a829c499246c440c165aa4fb9b68b66 571 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 384 558 1.6E-30 T 22-04-2016 IPR031475 Putative nucleotide-binding C-terminal domain TOLA_RS16205 7a829c499246c440c165aa4fb9b68b66 571 SUPERFAMILY SSF142764 130 564 2.62E-83 T 22-04-2016 TOLA_RS16205 7a829c499246c440c165aa4fb9b68b66 571 Pfam PF07005 Putative sugar-binding N-terminal domain 130 355 5.1E-53 T 22-04-2016 IPR010737 Putative sugar-binding, N-terminal domain TOLA_RS16205 7a829c499246c440c165aa4fb9b68b66 571 Pfam PF03612 Sorbitol phosphotransferase enzyme II N-terminus 6 123 6.7E-51 T 22-04-2016 IPR011618 Sorbitol phosphotransferase enzyme II, N-terminal GO:0008982|GO:0009401|GO:0016021 TOLA_RS16205 7a829c499246c440c165aa4fb9b68b66 571 PANTHER PTHR39427 1 122 2.7E-38 T 22-04-2016 TOLA_RS04955 f9623cf6dda2cfbc5d190ef870949a91 183 PANTHER PTHR33219:SF5 1 183 1.3E-71 T 22-04-2016 TOLA_RS04955 f9623cf6dda2cfbc5d190ef870949a91 183 PANTHER PTHR33219 1 183 1.3E-71 T 22-04-2016 TOLA_RS04955 f9623cf6dda2cfbc5d190ef870949a91 183 Pfam PF02325 YGGT family 107 170 6.1E-18 T 22-04-2016 IPR003425 CCB3/YggT GO:0016020 TOLA_RS04955 f9623cf6dda2cfbc5d190ef870949a91 183 Pfam PF02325 YGGT family 10 77 1.1E-20 T 22-04-2016 IPR003425 CCB3/YggT GO:0016020 TOLA_RS01095 afae1b6da7e30caec8a0171200054564 447 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 16 444 7.3E-136 T 22-04-2016 IPR010263 Type VI secretion protein, VC_A0114 TOLA_RS01095 afae1b6da7e30caec8a0171200054564 447 PANTHER PTHR35566:SF1 1 447 3.1E-129 T 22-04-2016 TOLA_RS01095 afae1b6da7e30caec8a0171200054564 447 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 2 446 3.9E-129 T 22-04-2016 IPR010263 Type VI secretion protein, VC_A0114 TOLA_RS01095 afae1b6da7e30caec8a0171200054564 447 PANTHER PTHR35566 1 447 3.1E-129 T 22-04-2016 TOLA_RS10510 7c78f0cf1a5bedbf11bac2f72d840cb1 229 Gene3D G3DSA:1.10.10.10 128 226 5.4E-35 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10510 7c78f0cf1a5bedbf11bac2f72d840cb1 229 SMART SM00448 3 116 1.6E-45 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS10510 7c78f0cf1a5bedbf11bac2f72d840cb1 229 SMART SM00862 150 225 1.6E-25 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS10510 7c78f0cf1a5bedbf11bac2f72d840cb1 229 SUPERFAMILY SSF52172 3 183 1.25E-43 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS10510 7c78f0cf1a5bedbf11bac2f72d840cb1 229 PANTHER PTHR26402 3 229 1.1E-144 T 22-04-2016 TOLA_RS10510 7c78f0cf1a5bedbf11bac2f72d840cb1 229 Gene3D G3DSA:3.40.50.2300 2 127 4.0E-42 T 22-04-2016 TOLA_RS10510 7c78f0cf1a5bedbf11bac2f72d840cb1 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 225 1.1E-26 T 22-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TOLA_RS10510 7c78f0cf1a5bedbf11bac2f72d840cb1 229 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 226 7.6E-112 T 22-04-2016 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 TOLA_RS10510 7c78f0cf1a5bedbf11bac2f72d840cb1 229 Pfam PF00072 Response regulator receiver domain 5 117 4.6E-28 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS10510 7c78f0cf1a5bedbf11bac2f72d840cb1 229 PANTHER PTHR26402:SF576 3 229 1.1E-144 T 22-04-2016 TOLA_RS06760 ce1f560b8d92e27273882f7d4dcb849e 475 Gene3D G3DSA:1.20.1250.20 268 461 9.3E-20 T 22-04-2016 TOLA_RS06760 ce1f560b8d92e27273882f7d4dcb849e 475 PANTHER PTHR23501 7 458 1.5E-111 T 22-04-2016 TOLA_RS06760 ce1f560b8d92e27273882f7d4dcb849e 475 Pfam PF07690 Major Facilitator Superfamily 15 407 2.2E-44 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS06760 ce1f560b8d92e27273882f7d4dcb849e 475 SUPERFAMILY SSF103473 245 459 1.02E-61 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS06760 ce1f560b8d92e27273882f7d4dcb849e 475 SUPERFAMILY SSF103473 7 195 1.02E-61 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS06760 ce1f560b8d92e27273882f7d4dcb849e 475 Gene3D G3DSA:1.20.1250.20 8 191 1.2E-19 T 22-04-2016 TOLA_RS09950 b5d8d6993dfe62f4696d7b8b066068d3 257 PANTHER PTHR30269 1 257 2.3E-51 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 TOLA_RS09950 b5d8d6993dfe62f4696d7b8b066068d3 257 Pfam PF01925 Sulfite exporter TauE/SafE 2 252 2.3E-47 T 22-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 TOLA_RS09950 b5d8d6993dfe62f4696d7b8b066068d3 257 PANTHER PTHR30269:SF18 1 257 2.3E-51 T 22-04-2016 TOLA_RS10970 2e7d1208540404f0b52504c4ff7087e9 558 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 293 503 2.1E-38 T 22-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TOLA_RS10970 2e7d1208540404f0b52504c4ff7087e9 558 Hamap MF_00520 Ribulokinase [araB]. 3 556 50.307 T 22-04-2016 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16|UniPathway: UPA00145 TOLA_RS10970 2e7d1208540404f0b52504c4ff7087e9 558 PANTHER PTHR10196 1 552 0.0 T 22-04-2016 TOLA_RS10970 2e7d1208540404f0b52504c4ff7087e9 558 SUPERFAMILY SSF53067 290 551 5.18E-46 T 22-04-2016 TOLA_RS10970 2e7d1208540404f0b52504c4ff7087e9 558 Gene3D G3DSA:3.30.420.40 290 551 3.3E-50 T 22-04-2016 TOLA_RS10970 2e7d1208540404f0b52504c4ff7087e9 558 SUPERFAMILY SSF53067 6 286 5.96E-22 T 22-04-2016 TOLA_RS10970 2e7d1208540404f0b52504c4ff7087e9 558 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 5 549 8.0E-217 T 22-04-2016 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16|UniPathway: UPA00145 TOLA_RS10970 2e7d1208540404f0b52504c4ff7087e9 558 PANTHER PTHR10196:SF62 1 552 0.0 T 22-04-2016 TOLA_RS10970 2e7d1208540404f0b52504c4ff7087e9 558 Gene3D G3DSA:3.30.420.40 2 284 8.8E-32 T 22-04-2016 TOLA_RS15730 76e0c261408d61b219f80e560d844e06 274 PANTHER PTHR10000 3 274 1.7E-66 T 22-04-2016 TOLA_RS15730 76e0c261408d61b219f80e560d844e06 274 Gene3D G3DSA:3.40.50.1000 176 272 6.1E-47 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS15730 76e0c261408d61b219f80e560d844e06 274 Gene3D G3DSA:3.40.50.1000 3 72 6.1E-47 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS15730 76e0c261408d61b219f80e560d844e06 274 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 240 2.6E-19 T 22-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 TOLA_RS15730 76e0c261408d61b219f80e560d844e06 274 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 268 2.1E-51 T 22-04-2016 IPR000150 Cof protein GO:0016787 TOLA_RS15730 76e0c261408d61b219f80e560d844e06 274 PANTHER PTHR10000:SF8 3 274 1.7E-66 T 22-04-2016 TOLA_RS15730 76e0c261408d61b219f80e560d844e06 274 SUPERFAMILY SSF56784 3 272 3.09E-61 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS15730 76e0c261408d61b219f80e560d844e06 274 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 268 3.0E-57 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS15730 76e0c261408d61b219f80e560d844e06 274 ProSitePatterns PS01229 Hypothetical cof family signature 2. 221 243 - T 22-04-2016 TOLA_RS13725 a54e36211fad56ff414a392768b565ba 730 Pfam PF02446 4-alpha-glucanotransferase 184 701 4.1E-126 T 22-04-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TOLA_RS13725 a54e36211fad56ff414a392768b565ba 730 PANTHER PTHR32438 14 598 3.0E-175 T 22-04-2016 TOLA_RS13725 a54e36211fad56ff414a392768b565ba 730 PANTHER PTHR32438 617 730 3.0E-175 T 22-04-2016 TOLA_RS13725 a54e36211fad56ff414a392768b565ba 730 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 137 717 1.3E-185 T 22-04-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TOLA_RS13725 a54e36211fad56ff414a392768b565ba 730 PANTHER PTHR32438:SF5 14 598 3.0E-175 T 22-04-2016 TOLA_RS13725 a54e36211fad56ff414a392768b565ba 730 PANTHER PTHR32438:SF5 617 730 3.0E-175 T 22-04-2016 TOLA_RS13725 a54e36211fad56ff414a392768b565ba 730 Gene3D G3DSA:3.20.20.80 649 709 1.1E-155 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS13725 a54e36211fad56ff414a392768b565ba 730 Gene3D G3DSA:3.20.20.80 175 610 1.1E-155 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS13725 a54e36211fad56ff414a392768b565ba 730 SUPERFAMILY SSF51445 168 597 3.08E-146 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS13725 a54e36211fad56ff414a392768b565ba 730 SUPERFAMILY SSF51445 636 723 3.08E-146 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS04965 21844b91a0bc7baed4a009771b374aac 233 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 80 94 - T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 TOLA_RS04965 21844b91a0bc7baed4a009771b374aac 233 SUPERFAMILY SSF51419 1 228 1.05E-83 T 22-04-2016 IPR029066 PLP-binding barrel TOLA_RS04965 21844b91a0bc7baed4a009771b374aac 233 Gene3D G3DSA:3.20.20.10 1 232 1.7E-92 T 22-04-2016 IPR029066 PLP-binding barrel TOLA_RS04965 21844b91a0bc7baed4a009771b374aac 233 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 230 8.8E-86 T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 TOLA_RS04965 21844b91a0bc7baed4a009771b374aac 233 PIRSF PIRSF004848 1 233 5.0E-80 T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 TOLA_RS04965 21844b91a0bc7baed4a009771b374aac 233 PANTHER PTHR10146 1 232 1.0E-100 T 22-04-2016 IPR011078 Uncharacterised protein family UPF0001 TOLA_RS04965 21844b91a0bc7baed4a009771b374aac 233 Pfam PF01168 Alanine racemase, N-terminal domain 10 230 2.4E-30 T 22-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 TOLA_RS06170 ef516d31d294053e2a3c201b51e7e79d 179 Gene3D G3DSA:3.30.420.130 1 98 3.8E-17 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS06170 ef516d31d294053e2a3c201b51e7e79d 179 SUPERFAMILY SSF53146 1 108 1.96E-16 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS06170 ef516d31d294053e2a3c201b51e7e79d 179 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 9 94 6.4E-11 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS07825 121c2e8fc2a604bb73510aca67b4d8c0 264 PANTHER PTHR39330 1 259 3.3E-99 T 22-04-2016 TOLA_RS07825 121c2e8fc2a604bb73510aca67b4d8c0 264 PIRSF PIRSF018982 1 252 2.2E-98 T 22-04-2016 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 TOLA_RS07825 121c2e8fc2a604bb73510aca67b4d8c0 264 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 9 242 2.8E-94 T 22-04-2016 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 TOLA_RS02555 1bb712be2b0ba9dcf29efd47d95cd223 283 PIRSF PIRSF004750 9 283 1.4E-125 T 22-04-2016 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS02555 1bb712be2b0ba9dcf29efd47d95cd223 283 PANTHER PTHR34354:SF1 5 283 6.9E-94 T 22-04-2016 TOLA_RS02555 1bb712be2b0ba9dcf29efd47d95cd223 283 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 283 157.223 T 22-04-2016 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS02555 1bb712be2b0ba9dcf29efd47d95cd223 283 PANTHER PTHR34354 5 283 6.9E-94 T 22-04-2016 TOLA_RS02555 1bb712be2b0ba9dcf29efd47d95cd223 283 Pfam PF14489 QueF-like protein 197 271 1.8E-25 T 22-04-2016 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS02555 1bb712be2b0ba9dcf29efd47d95cd223 283 Gene3D G3DSA:3.30.1130.10 24 137 3.7E-40 T 22-04-2016 TOLA_RS02555 1bb712be2b0ba9dcf29efd47d95cd223 283 Gene3D G3DSA:3.30.1130.10 146 283 3.4E-53 T 22-04-2016 TOLA_RS02555 1bb712be2b0ba9dcf29efd47d95cd223 283 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 24 133 3.1E-47 T 22-04-2016 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS02555 1bb712be2b0ba9dcf29efd47d95cd223 283 TIGRFAM TIGR03138 QueF: queuine synthase 14 283 1.2E-125 T 22-04-2016 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS02555 1bb712be2b0ba9dcf29efd47d95cd223 283 SUPERFAMILY SSF55620 187 268 3.48E-10 T 22-04-2016 TOLA_RS14000 770dee36e65bd18d399c23176a2b0a9c 160 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 22-04-2016 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS14000 770dee36e65bd18d399c23176a2b0a9c 160 Pfam PF02542 YgbB family 2 155 5.0E-63 T 22-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS14000 770dee36e65bd18d399c23176a2b0a9c 160 SUPERFAMILY SSF69765 1 157 4.97E-64 T 22-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS14000 770dee36e65bd18d399c23176a2b0a9c 160 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 35.185 T 22-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS14000 770dee36e65bd18d399c23176a2b0a9c 160 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 156 1.4E-66 T 22-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS14000 770dee36e65bd18d399c23176a2b0a9c 160 PANTHER PTHR32125 1 160 2.3E-60 T 22-04-2016 TOLA_RS14000 770dee36e65bd18d399c23176a2b0a9c 160 Gene3D G3DSA:3.30.1330.50 1 157 3.0E-69 T 22-04-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 TOLA_RS10135 df86be751fe5cc1429471fbec3533db5 387 PANTHER PTHR23501:SF79 5 387 1.4E-108 T 22-04-2016 TOLA_RS10135 df86be751fe5cc1429471fbec3533db5 387 Gene3D G3DSA:1.20.1250.20 205 381 3.8E-17 T 22-04-2016 TOLA_RS10135 df86be751fe5cc1429471fbec3533db5 387 Gene3D G3DSA:1.20.1250.20 9 190 1.8E-20 T 22-04-2016 TOLA_RS10135 df86be751fe5cc1429471fbec3533db5 387 SUPERFAMILY SSF103473 5 381 2.62E-48 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS10135 df86be751fe5cc1429471fbec3533db5 387 PANTHER PTHR23501 5 387 1.4E-108 T 22-04-2016 TOLA_RS10135 df86be751fe5cc1429471fbec3533db5 387 Pfam PF07690 Major Facilitator Superfamily 14 321 1.5E-31 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS02310 f9913d197a4709a9f828ac76fbd88312 349 PANTHER PTHR30505:SF1 4 336 1.3E-122 T 22-04-2016 TOLA_RS02310 f9913d197a4709a9f828ac76fbd88312 349 Pfam PF02378 Phosphotransferase system, EIIC 19 274 5.4E-15 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS02310 f9913d197a4709a9f828ac76fbd88312 349 PANTHER PTHR30505 4 336 1.3E-122 T 22-04-2016 TOLA_RS02310 f9913d197a4709a9f828ac76fbd88312 349 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 7 337 2.9E-93 T 22-04-2016 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 TOLA_RS06145 a93c4fa638c652530d077b0e89afceb6 142 Gene3D G3DSA:2.40.50.100 1 69 1.5E-26 T 22-04-2016 TOLA_RS06145 a93c4fa638c652530d077b0e89afceb6 142 Gene3D G3DSA:2.40.50.100 72 140 5.6E-25 T 22-04-2016 TOLA_RS06145 a93c4fa638c652530d077b0e89afceb6 142 Pfam PF03459 TOBE domain 4 66 2.9E-15 T 22-04-2016 IPR005116 Transport-associated OB, type 1 TOLA_RS06145 a93c4fa638c652530d077b0e89afceb6 142 Pfam PF03459 TOBE domain 76 138 4.8E-13 T 22-04-2016 IPR005116 Transport-associated OB, type 1 TOLA_RS06145 a93c4fa638c652530d077b0e89afceb6 142 SUPERFAMILY SSF50331 74 140 3.16E-17 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS06145 a93c4fa638c652530d077b0e89afceb6 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 1 68 1.0E-21 T 22-04-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 TOLA_RS06145 a93c4fa638c652530d077b0e89afceb6 142 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 74 140 6.4E-18 T 22-04-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 TOLA_RS06145 a93c4fa638c652530d077b0e89afceb6 142 SUPERFAMILY SSF50331 1 71 4.62E-20 T 22-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal TOLA_RS04310 fc8ed5eea85c64b4c9dc19cb37bd1c71 480 Pfam PF02378 Phosphotransferase system, EIIC 12 323 3.6E-79 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS04310 fc8ed5eea85c64b4c9dc19cb37bd1c71 480 Pfam PF00367 phosphotransferase system, EIIB 407 439 8.5E-14 T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS04310 fc8ed5eea85c64b4c9dc19cb37bd1c71 480 PANTHER PTHR30009 5 477 1.6E-237 T 22-04-2016 TOLA_RS04310 fc8ed5eea85c64b4c9dc19cb37bd1c71 480 Gene3D G3DSA:3.30.1360.60 402 478 4.5E-27 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS04310 fc8ed5eea85c64b4c9dc19cb37bd1c71 480 SUPERFAMILY SSF55604 404 476 9.68E-21 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS04310 fc8ed5eea85c64b4c9dc19cb37bd1c71 480 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 1 478 9.4E-213 T 22-04-2016 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0015758|GO:0016021 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS04310 fc8ed5eea85c64b4c9dc19cb37bd1c71 480 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 380 463 6.7E-21 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS04310 fc8ed5eea85c64b4c9dc19cb37bd1c71 480 PANTHER PTHR30009:SF2 5 477 1.6E-237 T 22-04-2016 TOLA_RS04310 fc8ed5eea85c64b4c9dc19cb37bd1c71 480 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 417 434 - T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS01500 bcad2befffc4ff74159b828cc865bb90 178 Pfam PF05068 Mannitol repressor 10 172 1.9E-56 T 22-04-2016 IPR007761 Mannitol repressor TOLA_RS01500 bcad2befffc4ff74159b828cc865bb90 178 SUPERFAMILY SSF158668 7 172 2.88E-54 T 22-04-2016 TOLA_RS01500 bcad2befffc4ff74159b828cc865bb90 178 PANTHER PTHR37941 9 175 1.6E-26 T 22-04-2016 TOLA_RS01500 bcad2befffc4ff74159b828cc865bb90 178 Gene3D G3DSA:1.20.120.330 6 173 2.0E-54 T 22-04-2016 TOLA_RS07215 18b394d92df8138a9e739022059a63c6 453 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 55 305 8.5E-69 T 22-04-2016 IPR031811 AlgX, SGNH hydrolase-like domain KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.-|UniPathway: UPA00286 TOLA_RS07215 18b394d92df8138a9e739022059a63c6 453 Pfam PF16824 C-terminal carbohydrate-binding module 326 443 9.6E-17 T 22-04-2016 IPR031798 Alginate biosynthesis protein AlgX, C-terminal carbohydrate-binding module KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.-|UniPathway: UPA00286 TOLA_RS04410 41a9a04d17c5e4648e6eefeb3d5a19fd 97 Gene3D G3DSA:1.10.1220.10 50 90 6.8E-4 T 22-04-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TOLA_RS04410 41a9a04d17c5e4648e6eefeb3d5a19fd 97 Pfam PF01402 Ribbon-helix-helix protein, copG family 52 88 2.5E-6 T 22-04-2016 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TOLA_RS15185 a454d6db51db8979c8ae6f60a95c2f34 283 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 283 2.1E-43 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 TOLA_RS15185 a454d6db51db8979c8ae6f60a95c2f34 283 Gene3D G3DSA:3.30.572.10 1 283 2.9E-79 T 22-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 TOLA_RS15185 a454d6db51db8979c8ae6f60a95c2f34 283 Hamap MF_00008 Thymidylate synthase [thyA]. 1 283 33.333 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 TOLA_RS15185 a454d6db51db8979c8ae6f60a95c2f34 283 PRINTS PR00108 Thymidylate synthase family signature 44 65 1.1E-13 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 TOLA_RS15185 a454d6db51db8979c8ae6f60a95c2f34 283 PRINTS PR00108 Thymidylate synthase family signature 173 199 1.1E-13 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 TOLA_RS15185 a454d6db51db8979c8ae6f60a95c2f34 283 PRINTS PR00108 Thymidylate synthase family signature 129 148 1.1E-13 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 TOLA_RS15185 a454d6db51db8979c8ae6f60a95c2f34 283 PRINTS PR00108 Thymidylate synthase family signature 211 228 1.1E-13 T 22-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 TOLA_RS15185 a454d6db51db8979c8ae6f60a95c2f34 283 Pfam PF00303 Thymidylate synthase 2 283 9.8E-75 T 22-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 TOLA_RS15185 a454d6db51db8979c8ae6f60a95c2f34 283 PANTHER PTHR11548 1 283 9.6E-103 T 22-04-2016 TOLA_RS15185 a454d6db51db8979c8ae6f60a95c2f34 283 SUPERFAMILY SSF55831 1 283 3.01E-93 T 22-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 TOLA_RS13230 8de89811b48a635370844c81d79ba062 269 SUPERFAMILY SSF69917 61 269 9.42E-22 T 22-04-2016 IPR020080 Outer membrane adhesin/peptidase omptin GO:0004190 TOLA_RS13230 8de89811b48a635370844c81d79ba062 269 Gene3D G3DSA:2.40.128.100 131 269 2.1E-11 T 22-04-2016 IPR009876 Outer membrane adhesin OpcA TOLA_RS13230 8de89811b48a635370844c81d79ba062 269 Pfam PF13505 Outer membrane protein beta-barrel domain 15 215 1.7E-10 T 22-04-2016 IPR027385 Outer membrane protein beta-barrel TOLA_RS02185 1cf28050d3017e3828f28b37bfe4fce9 707 SUPERFAMILY SSF51998 123 688 5.8E-193 T 22-04-2016 TOLA_RS02185 1cf28050d3017e3828f28b37bfe4fce9 707 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 117 706 1.0E-200 T 22-04-2016 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 TOLA_RS02185 1cf28050d3017e3828f28b37bfe4fce9 707 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 118 706 2.7E-179 T 22-04-2016 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 TOLA_RS02185 1cf28050d3017e3828f28b37bfe4fce9 707 Gene3D G3DSA:3.20.70.20 126 686 8.4E-182 T 22-04-2016 TOLA_RS02185 1cf28050d3017e3828f28b37bfe4fce9 707 ProSitePatterns PS00850 Glycine radical domain signature. 677 685 - T 22-04-2016 IPR019777 Formate C-acetyltransferase glycine radical, conserved site TOLA_RS02185 1cf28050d3017e3828f28b37bfe4fce9 707 PANTHER PTHR21075 1 707 4.5E-295 T 22-04-2016 TOLA_RS02185 1cf28050d3017e3828f28b37bfe4fce9 707 Pfam PF03477 ATP cone domain 7 91 2.8E-19 T 22-04-2016 IPR005144 ATP-cone domain TOLA_RS04455 fb5abf7e2cedc7034c97627948783cbc 470 Pfam PF04317 YcjX-like family, DUF463 26 469 9.0E-170 T 22-04-2016 IPR007413 Protein of unknown function DUF463, YcjX-like protein TOLA_RS04455 fb5abf7e2cedc7034c97627948783cbc 470 PANTHER PTHR38605:SF1 4 470 4.6E-163 T 22-04-2016 TOLA_RS04455 fb5abf7e2cedc7034c97627948783cbc 470 PANTHER PTHR38605 4 470 4.6E-163 T 22-04-2016 TOLA_RS04455 fb5abf7e2cedc7034c97627948783cbc 470 PIRSF PIRSF019381 2 470 1.5E-168 T 22-04-2016 IPR007413 Protein of unknown function DUF463, YcjX-like protein TOLA_RS11350 64ed87993981f4a2a9cbfb7918c40b69 738 SUPERFAMILY SSF56281 478 701 1.14E-40 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS11350 64ed87993981f4a2a9cbfb7918c40b69 738 Gene3D G3DSA:3.60.15.10 478 695 3.4E-31 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS11350 64ed87993981f4a2a9cbfb7918c40b69 738 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 70 696 1.2E-121 T 22-04-2016 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 TOLA_RS11350 64ed87993981f4a2a9cbfb7918c40b69 738 PANTHER PTHR30619:SF2 1 727 8.1E-161 T 22-04-2016 TOLA_RS11350 64ed87993981f4a2a9cbfb7918c40b69 738 SMART SM00849 490 674 2.7E-5 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS11350 64ed87993981f4a2a9cbfb7918c40b69 738 PANTHER PTHR30619 1 727 8.1E-161 T 22-04-2016 TOLA_RS11350 64ed87993981f4a2a9cbfb7918c40b69 738 Pfam PF13567 Domain of unknown function (DUF4131) 11 159 7.8E-15 T 22-04-2016 IPR025405 Domain of unknown function DUF4131 TOLA_RS11350 64ed87993981f4a2a9cbfb7918c40b69 738 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 216 384 2.4E-30 T 22-04-2016 IPR004477 ComEC/Rec2-related protein TOLA_RS11350 64ed87993981f4a2a9cbfb7918c40b69 738 Pfam PF03772 Competence protein 194 450 1.1E-55 T 22-04-2016 IPR004477 ComEC/Rec2-related protein TOLA_RS03400 d807e9b370ec2cf4371226e64dc8e8b6 116 SUPERFAMILY SSF89360 1 91 3.34E-11 T 22-04-2016 IPR000361 FeS cluster biogenesis TOLA_RS03400 d807e9b370ec2cf4371226e64dc8e8b6 116 Gene3D G3DSA:2.60.300.12 1 90 7.2E-10 T 22-04-2016 IPR000361 FeS cluster biogenesis TOLA_RS11290 5ebaa44a184e39e2fcf8efa7facf0a22 110 Gene3D G3DSA:3.40.30.10 7 101 8.1E-33 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS11290 5ebaa44a184e39e2fcf8efa7facf0a22 110 Pfam PF00462 Glutaredoxin 16 80 1.9E-18 T 22-04-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 TOLA_RS11290 5ebaa44a184e39e2fcf8efa7facf0a22 110 SUPERFAMILY SSF52833 1 103 1.95E-35 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS11290 5ebaa44a184e39e2fcf8efa7facf0a22 110 PANTHER PTHR10293 1 100 2.5E-56 T 22-04-2016 IPR004480 Monothiol glutaredoxin-related TOLA_RS11290 5ebaa44a184e39e2fcf8efa7facf0a22 110 PIRSF PIRSF005894 1 107 9.8E-52 T 22-04-2016 IPR014434 Monothiol glutaredoxin TOLA_RS11290 5ebaa44a184e39e2fcf8efa7facf0a22 110 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 100 2.5E-46 T 22-04-2016 IPR004480 Monothiol glutaredoxin-related TOLA_RS10340 1c0c6ca690c6a4b1d8ca1a547b6884e0 342 Pfam PF00953 Glycosyl transferase family 4 77 225 1.1E-30 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS10340 1c0c6ca690c6a4b1d8ca1a547b6884e0 342 PANTHER PTHR22926 1 317 3.8E-39 T 22-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS10340 1c0c6ca690c6a4b1d8ca1a547b6884e0 342 PANTHER PTHR22926:SF3 1 317 3.8E-39 T 22-04-2016 TOLA_RS03815 238edd1c0a8f520d50ba3acf244e389d 302 Pfam PF10124 Mu-like prophage major head subunit gpT 9 302 2.0E-128 T 22-04-2016 IPR018774 Bacteriophage Mu, GpT TOLA_RS16055 86e4c761af39f02fb7865f07b6abf550 356 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 27 350 1.3E-82 T 22-04-2016 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX TOLA_RS16055 86e4c761af39f02fb7865f07b6abf550 356 PANTHER PTHR38043 30 349 1.5E-61 T 22-04-2016 TOLA_RS15325 bf603e2937042e716491d35983a26ce3 86 Pfam PF04193 PQ loop repeat 6 61 2.6E-12 T 22-04-2016 IPR006603 PQ-loop repeat TOLA_RS02535 bd8cd16668a9e18e8a3d5dced8237d30 366 PANTHER PTHR37524 1 359 3.5E-179 T 22-04-2016 TOLA_RS02535 bd8cd16668a9e18e8a3d5dced8237d30 366 Hamap MF_01551 Ribosomal RNA large subunit methyltransferase M [rlmM]. 1 354 80.425 T 22-04-2016 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 TOLA_RS02535 bd8cd16668a9e18e8a3d5dced8237d30 366 PANTHER PTHR37524:SF2 1 359 3.5E-179 T 22-04-2016 TOLA_RS02535 bd8cd16668a9e18e8a3d5dced8237d30 366 SUPERFAMILY SSF53335 183 295 2.29E-12 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS02535 bd8cd16668a9e18e8a3d5dced8237d30 366 PIRSF PIRSF028774 1 359 6.8E-170 T 22-04-2016 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 TOLA_RS02535 bd8cd16668a9e18e8a3d5dced8237d30 366 Gene3D G3DSA:3.40.50.150 183 295 1.3E-12 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS02535 bd8cd16668a9e18e8a3d5dced8237d30 366 Pfam PF01728 FtsJ-like methyltransferase 185 256 4.6E-7 T 22-04-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 TOLA_RS07355 4901f91dd19a6712fb2abe92d1f16ac1 421 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 11 402 3.6E-118 T 22-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 TOLA_RS07355 4901f91dd19a6712fb2abe92d1f16ac1 421 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 327 347 - T 22-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 TOLA_RS07355 4901f91dd19a6712fb2abe92d1f16ac1 421 PANTHER PTHR11119:SF49 1 420 6.3E-160 T 22-04-2016 TOLA_RS07355 4901f91dd19a6712fb2abe92d1f16ac1 421 Pfam PF00860 Permease family 16 378 5.2E-93 T 22-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 TOLA_RS07355 4901f91dd19a6712fb2abe92d1f16ac1 421 PANTHER PTHR11119 1 420 6.3E-160 T 22-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 48 6.5E-16 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 PANTHER PTHR32248 1 484 1.2E-179 T 22-04-2016 TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 PIRSF PIRSF000774 1 484 3.6E-158 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 Pfam PF04552 Sigma-54, DNA binding domain 324 482 4.9E-73 T 22-04-2016 IPR007634 RNA polymerase sigma factor 54, DNA-binding TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 Pfam PF04963 Sigma-54 factor, core binding domain 119 310 7.7E-62 T 22-04-2016 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 481 2.5E-162 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 PANTHER PTHR32248:SF4 1 484 1.2E-179 T 22-04-2016 TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 PRINTS PR00045 Sigma-54 factor signature 193 210 5.6E-32 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 PRINTS PR00045 Sigma-54 factor signature 399 410 5.6E-32 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 PRINTS PR00045 Sigma-54 factor signature 457 475 5.6E-32 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 PRINTS PR00045 Sigma-54 factor signature 383 395 5.6E-32 T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 462 469 - T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 TOLA_RS15070 3a3b1ee214037e45aa498d84efcec5c1 484 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 371 390 - T 22-04-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 TOLA_RS07535 3bda6e5dd9ff463d37d27a5cfc3c6e9f 103 Pfam PF11342 Protein of unknown function (DUF3144) 19 95 9.1E-29 T 22-04-2016 IPR021490 Protein of unknown function DUF3144 TOLA_RS09285 d21d83bae1846035631cc6c811eb5da3 148 Gene3D G3DSA:3.40.1650.10 1 147 3.1E-46 T 22-04-2016 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 TOLA_RS09285 d21d83bae1846035631cc6c811eb5da3 148 PANTHER PTHR31690 1 148 8.2E-42 T 22-04-2016 TOLA_RS09285 d21d83bae1846035631cc6c811eb5da3 148 SUPERFAMILY SSF102546 1 147 4.84E-41 T 22-04-2016 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 TOLA_RS09285 d21d83bae1846035631cc6c811eb5da3 148 Pfam PF05025 RbsD / FucU transport protein family 3 146 4.6E-31 T 22-04-2016 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 TOLA_RS15610 6ae4466810fa32df9561eb5b37430d2b 592 Pfam PF13649 Methyltransferase domain 42 137 9.2E-14 T 22-04-2016 TOLA_RS15610 6ae4466810fa32df9561eb5b37430d2b 592 SUPERFAMILY SSF53335 22 177 1.23E-26 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS15610 6ae4466810fa32df9561eb5b37430d2b 592 Gene3D G3DSA:3.40.50.150 20 187 1.0E-25 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS15610 6ae4466810fa32df9561eb5b37430d2b 592 Pfam PF13395 HNH endonuclease 486 523 1.2E-5 T 22-04-2016 IPR003615 HNH nuclease TOLA_RS11560 6f886961cd470b1cf66b9acda12d62b1 481 Pfam PF13148 Protein of unknown function (DUF3987) 32 398 1.4E-92 T 22-04-2016 IPR025048 Protein of unknown function DUF3987) TOLA_RS07805 ba068fbdc05a8c43530c8824af63733d 370 Gene3D G3DSA:2.60.120.650 2 193 1.5E-38 T 22-04-2016 TOLA_RS07805 ba068fbdc05a8c43530c8824af63733d 370 Pfam PF08007 Cupin superfamily protein 1 295 1.1E-85 T 22-04-2016 IPR003347 JmjC domain TOLA_RS07805 ba068fbdc05a8c43530c8824af63733d 370 PANTHER PTHR13096 1 303 2.0E-43 T 22-04-2016 TOLA_RS07805 ba068fbdc05a8c43530c8824af63733d 370 SMART SM00558 80 203 5.1E-6 T 22-04-2016 IPR003347 JmjC domain TOLA_RS07805 ba068fbdc05a8c43530c8824af63733d 370 SUPERFAMILY SSF51197 1 270 2.06E-64 T 22-04-2016 TOLA_RS13410 4306a73d859b6815c7346f5a2c0c459b 337 PRINTS PR01713 Nucleotide sugar epimerase signature 294 311 1.1E-7 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 TOLA_RS13410 4306a73d859b6815c7346f5a2c0c459b 337 PRINTS PR01713 Nucleotide sugar epimerase signature 255 270 1.1E-7 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 TOLA_RS13410 4306a73d859b6815c7346f5a2c0c459b 337 PRINTS PR01713 Nucleotide sugar epimerase signature 230 245 1.1E-7 T 22-04-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 TOLA_RS13410 4306a73d859b6815c7346f5a2c0c459b 337 PANTHER PTHR10366:SF39 2 337 1.1E-155 T 22-04-2016 TOLA_RS13410 4306a73d859b6815c7346f5a2c0c459b 337 Gene3D G3DSA:3.90.25.10 179 231 9.2E-56 T 22-04-2016 TOLA_RS13410 4306a73d859b6815c7346f5a2c0c459b 337 Gene3D G3DSA:3.90.25.10 263 336 9.2E-56 T 22-04-2016 TOLA_RS13410 4306a73d859b6815c7346f5a2c0c459b 337 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 334 1.4E-142 T 22-04-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|UniPathway: UPA00214 TOLA_RS13410 4306a73d859b6815c7346f5a2c0c459b 337 Gene3D G3DSA:3.40.50.720 1 178 8.5E-53 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS13410 4306a73d859b6815c7346f5a2c0c459b 337 PANTHER PTHR10366 2 337 1.1E-155 T 22-04-2016 TOLA_RS13410 4306a73d859b6815c7346f5a2c0c459b 337 SUPERFAMILY SSF51735 1 336 4.98E-99 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS13410 4306a73d859b6815c7346f5a2c0c459b 337 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 3.1E-68 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS13300 57a7b5e97fbbc53c0e856a8ba9a9783c 358 Pfam PF01761 3-dehydroquinate synthase 65 323 2.6E-110 T 22-04-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 TOLA_RS13300 57a7b5e97fbbc53c0e856a8ba9a9783c 358 Gene3D G3DSA:3.40.50.1970 3 170 2.1E-66 T 22-04-2016 TOLA_RS13300 57a7b5e97fbbc53c0e856a8ba9a9783c 358 PIRSF PIRSF001455 3 357 4.0E-108 T 22-04-2016 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 TOLA_RS13300 57a7b5e97fbbc53c0e856a8ba9a9783c 358 SUPERFAMILY SSF56796 4 354 7.46E-119 T 22-04-2016 TOLA_RS13300 57a7b5e97fbbc53c0e856a8ba9a9783c 358 PANTHER PTHR21090 2 356 2.8E-199 T 22-04-2016 TOLA_RS13300 57a7b5e97fbbc53c0e856a8ba9a9783c 358 Gene3D G3DSA:1.20.1090.10 171 355 4.0E-69 T 22-04-2016 TOLA_RS13300 57a7b5e97fbbc53c0e856a8ba9a9783c 358 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 356 43.794 T 22-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 TOLA_RS13300 57a7b5e97fbbc53c0e856a8ba9a9783c 358 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 350 7.4E-121 T 22-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 TOLA_RS15525 2328990cde6fe65bdeb45b4aaacc9f92 430 SUPERFAMILY SSF103473 5 412 2.22E-82 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS15525 2328990cde6fe65bdeb45b4aaacc9f92 430 Pfam PF07690 Major Facilitator Superfamily 17 378 6.9E-60 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS15525 2328990cde6fe65bdeb45b4aaacc9f92 430 PIRSF PIRSF002808 1 429 4.8E-43 T 22-04-2016 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 TOLA_RS15525 2328990cde6fe65bdeb45b4aaacc9f92 430 Gene3D G3DSA:1.20.1250.20 9 202 4.9E-50 T 22-04-2016 TOLA_RS15525 2328990cde6fe65bdeb45b4aaacc9f92 430 PANTHER PTHR11662:SF285 3 413 1.3E-212 T 22-04-2016 TOLA_RS15525 2328990cde6fe65bdeb45b4aaacc9f92 430 Gene3D G3DSA:1.20.1250.20 221 413 5.1E-25 T 22-04-2016 TOLA_RS15525 2328990cde6fe65bdeb45b4aaacc9f92 430 PANTHER PTHR11662 3 413 1.3E-212 T 22-04-2016 TOLA_RS10175 18701fe424e56f23aba53af222745bd4 347 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 269 281 9.7E-5 T 22-04-2016 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related TOLA_RS10175 18701fe424e56f23aba53af222745bd4 347 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 282 295 9.7E-5 T 22-04-2016 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related TOLA_RS10175 18701fe424e56f23aba53af222745bd4 347 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 125 135 9.7E-5 T 22-04-2016 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related TOLA_RS10175 18701fe424e56f23aba53af222745bd4 347 SUPERFAMILY SSF51430 12 326 9.43E-89 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS10175 18701fe424e56f23aba53af222745bd4 347 PANTHER PTHR11732:SF191 12 331 3.4E-180 T 22-04-2016 TOLA_RS10175 18701fe424e56f23aba53af222745bd4 347 Gene3D G3DSA:3.20.20.100 12 328 6.7E-88 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS10175 18701fe424e56f23aba53af222745bd4 347 PANTHER PTHR11732 12 331 3.4E-180 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta TOLA_RS10175 18701fe424e56f23aba53af222745bd4 347 Pfam PF00248 Aldo/keto reductase family 27 324 1.2E-69 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS07835 a9a59f925130c583c1363ff2fb9df893 187 PANTHER PTHR30178 2 187 7.4E-114 T 22-04-2016 TOLA_RS07835 a9a59f925130c583c1363ff2fb9df893 187 Pfam PF01184 GPR1/FUN34/yaaH family 2 175 5.9E-42 T 22-04-2016 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 TOLA_RS07835 a9a59f925130c583c1363ff2fb9df893 187 ProSitePatterns PS01114 GPR1/FUN34/yaaH family signature. 7 16 - T 22-04-2016 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 TOLA_RS07835 a9a59f925130c583c1363ff2fb9df893 187 PANTHER PTHR30178:SF6 2 187 7.4E-114 T 22-04-2016 TOLA_RS07055 969e7b14b54365179b724702c9c4e4d2 339 Gene3D G3DSA:3.90.226.10 90 196 2.2E-33 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS07055 969e7b14b54365179b724702c9c4e4d2 339 Gene3D G3DSA:3.90.226.10 262 292 2.2E-33 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS07055 969e7b14b54365179b724702c9c4e4d2 339 SUPERFAMILY SSF52096 90 200 5.97E-29 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS07055 969e7b14b54365179b724702c9c4e4d2 339 SUPERFAMILY SSF52096 231 290 5.97E-29 T 22-04-2016 IPR029045 ClpP/crotonase-like domain TOLA_RS07055 969e7b14b54365179b724702c9c4e4d2 339 Pfam PF01343 Peptidase family S49 153 300 5.0E-45 T 22-04-2016 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TOLA_RS07055 969e7b14b54365179b724702c9c4e4d2 339 PANTHER PTHR33209:SF2 1 333 2.0E-166 T 22-04-2016 TOLA_RS07055 969e7b14b54365179b724702c9c4e4d2 339 Pfam PF08496 Peptidase family S49 N-terminal 3 149 1.1E-52 T 22-04-2016 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 TOLA_RS07055 969e7b14b54365179b724702c9c4e4d2 339 PANTHER PTHR33209 1 333 2.0E-166 T 22-04-2016 TOLA_RS01270 4669c6cc113079a1368f4fb97d4be31b 235 Pfam PF01564 Spermine/spermidine synthase 42 207 3.1E-8 T 22-04-2016 TOLA_RS01270 4669c6cc113079a1368f4fb97d4be31b 235 SUPERFAMILY SSF53335 18 223 3.82E-34 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS01270 4669c6cc113079a1368f4fb97d4be31b 235 Gene3D G3DSA:3.40.50.150 32 224 1.3E-40 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS14875 94506b8bcbd50349cef28232f863705e 358 Pfam PF13379 NMT1-like family 45 259 6.6E-9 T 22-04-2016 TOLA_RS14875 94506b8bcbd50349cef28232f863705e 358 PANTHER PTHR30024 11 290 2.5E-13 T 22-04-2016 TOLA_RS14875 94506b8bcbd50349cef28232f863705e 358 Gene3D G3DSA:3.40.190.10 130 239 3.7E-13 T 22-04-2016 TOLA_RS14875 94506b8bcbd50349cef28232f863705e 358 TIGRFAM TIGR03427 ABC_peri_uca: ABC transporter periplasmic binding protein, urea carboxylase region 32 358 2.3E-169 T 22-04-2016 IPR017793 ABC transporter, urea utilisation-associated, substrate-binding protein TOLA_RS14875 94506b8bcbd50349cef28232f863705e 358 SUPERFAMILY SSF53850 39 245 2.81E-36 T 22-04-2016 TOLA_RS15930 672f1a798e15625c07b35505c24fbef1 101 Gene3D G3DSA:3.40.50.270 1 101 1.6E-38 T 22-04-2016 TOLA_RS15930 672f1a798e15625c07b35505c24fbef1 101 SUPERFAMILY SSF52794 1 101 2.38E-36 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS15930 672f1a798e15625c07b35505c24fbef1 101 PANTHER PTHR34581 2 101 7.7E-41 T 22-04-2016 TOLA_RS15930 672f1a798e15625c07b35505c24fbef1 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 7.4E-25 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS15930 672f1a798e15625c07b35505c24fbef1 101 PANTHER PTHR34581:SF2 2 101 7.7E-41 T 22-04-2016 TOLA_RS09240 644df3f738da86209e7528568c39ef57 143 PANTHER PTHR30353:SF12 1 142 5.9E-53 T 22-04-2016 TOLA_RS09240 644df3f738da86209e7528568c39ef57 143 PANTHER PTHR30353 1 142 5.9E-53 T 22-04-2016 IPR032818 DedA family TOLA_RS09240 644df3f738da86209e7528568c39ef57 143 Pfam PF09335 SNARE associated Golgi protein 22 140 6.4E-16 T 22-04-2016 IPR032816 SNARE associated Golgi protein TOLA_RS09240 644df3f738da86209e7528568c39ef57 143 ProDom PD085709 MEMBRANE RP436 UNCHARACTERIZED INTEGRAL PREDICTED TRANSMEMBRANE 4 116 2.0E-4 T 22-04-2016 IPR020143 Uncharacterised protein family, RP436 TOLA_RS13030 eb10434812cbae763b11a582654a6a21 122 Pfam PF06062 Uncharacterised protein family (UPF0231) 1 119 3.0E-37 T 22-04-2016 IPR008249 Uncharacterised protein family UPF0231 TOLA_RS13030 eb10434812cbae763b11a582654a6a21 122 ProDom PD020773 UPF0231 YACL UNCHARACTERISED UCP006287 VC0605 UNCHARACTERIZED 3'REGION VV2750 BCR OXIDASE 4 119 1.0E-17 T 22-04-2016 IPR008249 Uncharacterised protein family UPF0231 TOLA_RS13030 eb10434812cbae763b11a582654a6a21 122 PIRSF PIRSF006287 1 122 2.0E-32 T 22-04-2016 IPR008249 Uncharacterised protein family UPF0231 TOLA_RS06675 36f4b2e67d2ed39889ff6ff7a30b6735 279 Gene3D G3DSA:3.40.250.10 3 136 6.8E-34 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS06675 36f4b2e67d2ed39889ff6ff7a30b6735 279 SUPERFAMILY SSF52821 2 138 1.28E-32 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS06675 36f4b2e67d2ed39889ff6ff7a30b6735 279 ProSitePatterns PS00683 Rhodanese C-terminal signature. 259 269 - T 22-04-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 TOLA_RS06675 36f4b2e67d2ed39889ff6ff7a30b6735 279 Gene3D G3DSA:3.40.250.10 152 278 8.5E-35 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS06675 36f4b2e67d2ed39889ff6ff7a30b6735 279 PANTHER PTHR11364 3 279 9.1E-90 T 22-04-2016 TOLA_RS06675 36f4b2e67d2ed39889ff6ff7a30b6735 279 SUPERFAMILY SSF52821 159 278 4.98E-30 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS06675 36f4b2e67d2ed39889ff6ff7a30b6735 279 SMART SM00450 6 130 6.0E-17 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS06675 36f4b2e67d2ed39889ff6ff7a30b6735 279 SMART SM00450 155 275 5.1E-18 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS06675 36f4b2e67d2ed39889ff6ff7a30b6735 279 Pfam PF00581 Rhodanese-like domain 7 126 1.2E-11 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS06675 36f4b2e67d2ed39889ff6ff7a30b6735 279 Pfam PF00581 Rhodanese-like domain 157 270 2.5E-9 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS08480 00ef68a85404361a617ef68d81a08684 225 PANTHER PTHR34857:SF1 1 225 3.2E-63 T 22-04-2016 TOLA_RS08480 00ef68a85404361a617ef68d81a08684 225 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 17 216 8.6E-49 T 22-04-2016 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 TOLA_RS08480 00ef68a85404361a617ef68d81a08684 225 PANTHER PTHR34857 1 225 3.2E-63 T 22-04-2016 TOLA_RS08480 00ef68a85404361a617ef68d81a08684 225 Pfam PF02361 Cobalt transport protein 12 221 2.2E-40 T 22-04-2016 IPR003339 ABC/ECF transporter, transmembrane component TOLA_RS02205 859a1f17a673d246922ccab3240fa4aa 210 SUPERFAMILY SSF52833 11 85 5.21E-21 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS02205 859a1f17a673d246922ccab3240fa4aa 210 Gene3D G3DSA:3.40.30.10 8 98 1.4E-26 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS02205 859a1f17a673d246922ccab3240fa4aa 210 Pfam PF02798 Glutathione S-transferase, N-terminal domain 10 80 3.2E-14 T 22-04-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TOLA_RS02205 859a1f17a673d246922ccab3240fa4aa 210 Pfam PF00043 Glutathione S-transferase, C-terminal domain 101 192 1.2E-10 T 22-04-2016 IPR004046 Glutathione S-transferase, C-terminal TOLA_RS02205 859a1f17a673d246922ccab3240fa4aa 210 PANTHER PTHR11260 9 206 3.9E-114 T 22-04-2016 TOLA_RS02205 859a1f17a673d246922ccab3240fa4aa 210 PANTHER PTHR11260:SF44 9 206 3.9E-114 T 22-04-2016 TOLA_RS02205 859a1f17a673d246922ccab3240fa4aa 210 SUPERFAMILY SSF47616 81 206 2.98E-25 T 22-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like TOLA_RS02205 859a1f17a673d246922ccab3240fa4aa 210 Gene3D G3DSA:1.20.1050.10 99 206 4.6E-18 T 22-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like TOLA_RS11190 ba642fac6cf1117f00bdc93dad00fe5a 302 Gene3D G3DSA:3.40.50.620 20 204 1.5E-22 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS11190 ba642fac6cf1117f00bdc93dad00fe5a 302 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 7 268 58.009 T 22-04-2016 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 TOLA_RS11190 ba642fac6cf1117f00bdc93dad00fe5a 302 PANTHER PTHR11807:SF16 7 263 3.6E-119 T 22-04-2016 TOLA_RS11190 ba642fac6cf1117f00bdc93dad00fe5a 302 SUPERFAMILY SSF52402 14 232 2.12E-54 T 22-04-2016 TOLA_RS11190 ba642fac6cf1117f00bdc93dad00fe5a 302 PIRSF PIRSF004976 2 269 4.6E-76 T 22-04-2016 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 TOLA_RS11190 ba642fac6cf1117f00bdc93dad00fe5a 302 PANTHER PTHR11807 7 263 3.6E-119 T 22-04-2016 TOLA_RS11190 ba642fac6cf1117f00bdc93dad00fe5a 302 Pfam PF01171 PP-loop family 39 202 1.9E-14 T 22-04-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal TOLA_RS12625 afcce5ec328580930adae33ee78a25dd 296 Pfam PF03466 LysR substrate binding domain 87 294 1.2E-36 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS12625 afcce5ec328580930adae33ee78a25dd 296 Gene3D G3DSA:3.40.190.10 89 175 5.8E-21 T 22-04-2016 TOLA_RS12625 afcce5ec328580930adae33ee78a25dd 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.7E-10 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS12625 afcce5ec328580930adae33ee78a25dd 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.7E-10 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS12625 afcce5ec328580930adae33ee78a25dd 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.7E-10 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS12625 afcce5ec328580930adae33ee78a25dd 296 SUPERFAMILY SSF46785 1 85 5.05E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS12625 afcce5ec328580930adae33ee78a25dd 296 Gene3D G3DSA:3.40.190.10 176 261 3.1E-18 T 22-04-2016 TOLA_RS12625 afcce5ec328580930adae33ee78a25dd 296 PANTHER PTHR30346 1 294 7.3E-89 T 22-04-2016 TOLA_RS12625 afcce5ec328580930adae33ee78a25dd 296 Gene3D G3DSA:1.10.10.10 1 85 9.0E-31 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS12625 afcce5ec328580930adae33ee78a25dd 296 PANTHER PTHR30346:SF6 1 294 7.3E-89 T 22-04-2016 TOLA_RS12625 afcce5ec328580930adae33ee78a25dd 296 SUPERFAMILY SSF53850 88 295 9.15E-37 T 22-04-2016 TOLA_RS12625 afcce5ec328580930adae33ee78a25dd 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.4E-21 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS03735 3f9e0e8aaadd2ecc67e7a526604bc89c 194 Pfam PF06252 Protein of unknown function (DUF1018) 23 151 4.4E-32 T 22-04-2016 IPR009363 Bacteriophage Mu, Gp16 TOLA_RS11890 32e734b6e98a24918d37bafe6710c3f5 411 PIRSF PIRSF006060 1 401 9.6E-55 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 TOLA_RS11890 32e734b6e98a24918d37bafe6710c3f5 411 PANTHER PTHR11785:SF415 4 383 1.5E-84 T 22-04-2016 TOLA_RS11890 32e734b6e98a24918d37bafe6710c3f5 411 PANTHER PTHR11785 4 383 1.5E-84 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 TOLA_RS11890 32e734b6e98a24918d37bafe6710c3f5 411 Pfam PF13520 Amino acid permease 8 396 9.7E-37 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 TOLA_RS01755 7261ff7fe3ee705e98d1426b9b2b07a3 206 Pfam PF02036 SCP-2 sterol transfer family 18 114 3.1E-10 T 22-04-2016 IPR003033 SCP2 sterol-binding domain TOLA_RS01755 7261ff7fe3ee705e98d1426b9b2b07a3 206 PANTHER PTHR38693:SF1 1 205 7.1E-38 T 22-04-2016 TOLA_RS01755 7261ff7fe3ee705e98d1426b9b2b07a3 206 PANTHER PTHR38693 1 205 7.1E-38 T 22-04-2016 TOLA_RS15880 e37f3dcaea4f490370382fa1230c1b65 511 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 10 508 3.2E-237 T 22-04-2016 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 TOLA_RS15880 e37f3dcaea4f490370382fa1230c1b65 511 PANTHER PTHR10314:SF30 3 363 2.4E-196 T 22-04-2016 TOLA_RS15880 e37f3dcaea4f490370382fa1230c1b65 511 Gene3D G3DSA:3.40.50.1100 75 329 1.5E-81 T 22-04-2016 TOLA_RS15880 e37f3dcaea4f490370382fa1230c1b65 511 PANTHER PTHR10314 3 363 2.4E-196 T 22-04-2016 TOLA_RS15880 e37f3dcaea4f490370382fa1230c1b65 511 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 48 61 - T 22-04-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TOLA_RS15880 e37f3dcaea4f490370382fa1230c1b65 511 SUPERFAMILY SSF53686 20 359 2.88E-104 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TOLA_RS15880 e37f3dcaea4f490370382fa1230c1b65 511 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 324 414 9.6E-24 T 22-04-2016 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 TOLA_RS15880 e37f3dcaea4f490370382fa1230c1b65 511 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 421 508 1.7E-25 T 22-04-2016 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 TOLA_RS15880 e37f3dcaea4f490370382fa1230c1b65 511 SUPERFAMILY SSF55021 415 508 3.05E-26 T 22-04-2016 TOLA_RS15880 e37f3dcaea4f490370382fa1230c1b65 511 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 311 2.8E-81 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TOLA_RS15880 e37f3dcaea4f490370382fa1230c1b65 511 Gene3D G3DSA:3.40.1020.10 335 508 1.0E-52 T 22-04-2016 TOLA_RS11585 dcd1a0fae0b76d17dbdcc3f389774271 115 Gene3D G3DSA:1.10.260.40 13 106 3.3E-16 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS11585 dcd1a0fae0b76d17dbdcc3f389774271 115 Pfam PF01381 Helix-turn-helix 17 71 2.0E-12 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS11585 dcd1a0fae0b76d17dbdcc3f389774271 115 SMART SM00530 16 71 2.6E-11 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS11585 dcd1a0fae0b76d17dbdcc3f389774271 115 SUPERFAMILY SSF47413 10 76 4.79E-15 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS03005 e8e4db2523ba47bdfad5b2f518a11d86 367 Pfam PF03702 Uncharacterised protein family (UPF0075) 3 366 2.6E-148 T 22-04-2016 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17|UniPathway: UPA00343|UniPathway: UPA00544 TOLA_RS03005 e8e4db2523ba47bdfad5b2f518a11d86 367 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 2 366 41.356 T 22-04-2016 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17|UniPathway: UPA00343|UniPathway: UPA00544 TOLA_RS03005 e8e4db2523ba47bdfad5b2f518a11d86 367 PANTHER PTHR30605:SF0 1 367 7.4E-160 T 22-04-2016 TOLA_RS03005 e8e4db2523ba47bdfad5b2f518a11d86 367 SUPERFAMILY SSF53067 141 338 1.94E-29 T 22-04-2016 TOLA_RS03005 e8e4db2523ba47bdfad5b2f518a11d86 367 SUPERFAMILY SSF53067 66 111 1.94E-29 T 22-04-2016 TOLA_RS03005 e8e4db2523ba47bdfad5b2f518a11d86 367 SUPERFAMILY SSF53067 3 34 1.94E-29 T 22-04-2016 TOLA_RS03005 e8e4db2523ba47bdfad5b2f518a11d86 367 PANTHER PTHR30605 1 367 7.4E-160 T 22-04-2016 TOLA_RS03005 e8e4db2523ba47bdfad5b2f518a11d86 367 Gene3D G3DSA:3.30.420.40 2 195 2.2E-74 T 22-04-2016 TOLA_RS13790 a20d3d7c36d5b08db3e0f5f039b93f0d 171 PANTHER PTHR30128 51 171 7.9E-50 T 22-04-2016 TOLA_RS13790 a20d3d7c36d5b08db3e0f5f039b93f0d 171 ProSitePatterns PS01068 OmpA-like domain. 103 147 - T 22-04-2016 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 TOLA_RS13790 a20d3d7c36d5b08db3e0f5f039b93f0d 171 SUPERFAMILY SSF103088 62 170 2.22E-32 T 22-04-2016 IPR006665 OmpA-like domain TOLA_RS13790 a20d3d7c36d5b08db3e0f5f039b93f0d 171 PANTHER PTHR30128:SF18 51 171 7.9E-50 T 22-04-2016 TOLA_RS13790 a20d3d7c36d5b08db3e0f5f039b93f0d 171 Gene3D G3DSA:3.30.1330.60 58 169 8.7E-31 T 22-04-2016 IPR006665 OmpA-like domain TOLA_RS13790 a20d3d7c36d5b08db3e0f5f039b93f0d 171 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 69 171 2.3E-41 T 22-04-2016 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 TOLA_RS13790 a20d3d7c36d5b08db3e0f5f039b93f0d 171 PRINTS PR01021 OMPA domain signature 101 116 1.7E-15 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TOLA_RS13790 a20d3d7c36d5b08db3e0f5f039b93f0d 171 PRINTS PR01021 OMPA domain signature 71 93 1.7E-15 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TOLA_RS13790 a20d3d7c36d5b08db3e0f5f039b93f0d 171 PRINTS PR01021 OMPA domain signature 116 132 1.7E-15 T 22-04-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 TOLA_RS13790 a20d3d7c36d5b08db3e0f5f039b93f0d 171 Pfam PF00691 OmpA family 70 164 5.0E-22 T 22-04-2016 IPR006665 OmpA-like domain TOLA_RS03670 399c8781df6d5ac2c0839a903e1983fd 241 Gene3D G3DSA:3.40.50.300 13 162 5.3E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03670 399c8781df6d5ac2c0839a903e1983fd 241 SUPERFAMILY SSF52540 13 228 5.4E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03670 399c8781df6d5ac2c0839a903e1983fd 241 Pfam PF13401 AAA domain 29 145 3.9E-21 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS03670 399c8781df6d5ac2c0839a903e1983fd 241 SMART SM00382 28 157 0.0035 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS08745 dcd3ea911b745d24a56fb5111e3b781e 154 Pfam PF14316 Domain of unknown function (DUF4381) 7 146 9.6E-22 T 22-04-2016 IPR025489 Protein of unknown function (DUF4381 TOLA_RS14125 d4af1c3b612b8a91404e4ce1298b8e1c 308 PANTHER PTHR30193:SF5 21 305 2.6E-136 T 22-04-2016 TOLA_RS14125 d4af1c3b612b8a91404e4ce1298b8e1c 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 303 1.8E-18 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS14125 d4af1c3b612b8a91404e4ce1298b8e1c 308 Gene3D G3DSA:1.10.3720.10 19 295 1.3E-50 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS14125 d4af1c3b612b8a91404e4ce1298b8e1c 308 PANTHER PTHR30193 21 305 2.6E-136 T 22-04-2016 TOLA_RS14125 d4af1c3b612b8a91404e4ce1298b8e1c 308 SUPERFAMILY SSF161098 19 300 4.49E-56 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS14645 67a282190802e1fc8a43b6cfb81f47d4 289 Pfam PF14305 TupA-like ATPgrasp 44 284 4.1E-45 T 22-04-2016 IPR029465 TupA-like ATPgrasp protein TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 SUPERFAMILY SSF52518 1 171 3.68E-63 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 SUPERFAMILY SSF52518 358 546 6.61E-64 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 Gene3D G3DSA:3.40.50.970 1 170 3.7E-74 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 PANTHER PTHR18968:SF116 1 549 7.3E-259 T 22-04-2016 TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 412 431 - T 22-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 375 523 1.7E-47 T 22-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 168 3.2E-58 T 22-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 PANTHER PTHR18968 1 549 7.3E-259 T 22-04-2016 TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 Gene3D G3DSA:3.40.50.970 339 538 7.5E-72 T 22-04-2016 IPR029061 Thiamin diphosphate-binding fold TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 SUPERFAMILY SSF52467 184 344 7.06E-55 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 1 547 4.8E-213 T 22-04-2016 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 187 322 1.4E-41 T 22-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TOLA_RS15860 327bdb8665e297673a13275b4c53d5f6 549 Gene3D G3DSA:3.40.50.1220 185 338 4.1E-55 T 22-04-2016 IPR029035 DHS-like NAD/FAD-binding domain TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PIRSF PIRSF019574 1 366 2.8E-139 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PANTHER PTHR30222 12 366 2.9E-173 T 22-04-2016 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PANTHER PTHR30222:SF11 12 366 2.9E-173 T 22-04-2016 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 Pfam PF13416 Bacterial extracellular solute-binding protein 43 319 2.5E-31 T 22-04-2016 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 Gene3D G3DSA:3.40.190.10 37 135 1.6E-9 T 22-04-2016 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 Gene3D G3DSA:3.40.190.10 136 314 6.2E-74 T 22-04-2016 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 75 89 5.8E-65 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 265 284 5.8E-65 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 124 140 5.8E-65 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 32 48 5.8E-65 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 155 169 5.8E-65 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 91 104 5.8E-65 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 178 197 5.8E-65 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 310 336 5.8E-65 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 48 69 5.8E-65 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 215 234 5.8E-65 T 22-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TOLA_RS14135 15fc2283424af071d1ab3c03b5d3083b 366 SUPERFAMILY SSF53850 26 365 1.22E-101 T 22-04-2016 TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 3.7E-176 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 SUPERFAMILY SSF81271 279 359 1.22E-35 T 22-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 Gene3D G3DSA:1.10.150.300 131 200 1.1E-28 T 22-04-2016 IPR023192 TGS-like domain TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 Pfam PF01926 50S ribosome-binding GTPase 5 120 3.5E-21 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 SUPERFAMILY SSF52540 3 301 1.24E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 PIRSF PIRSF006641 1 363 2.7E-159 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 Gene3D G3DSA:3.40.50.300 201 267 1.2E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 Gene3D G3DSA:3.40.50.300 4 130 1.2E-43 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 2.3E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 2.3E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 2.3E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 2.3E-34 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 PANTHER PTHR23305 1 363 2.3E-216 T 22-04-2016 TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 47.173 T 22-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 5.9E-39 T 22-04-2016 IPR013029 Domain of unknown function DUF933 TOLA_RS11700 39efd5915db94b14ea0f2fc4a1e79572 363 Gene3D G3DSA:3.10.20.30 268 363 2.1E-49 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS10110 509af9fb8c9c2bb07b5af7e5d392fcd2 99 PANTHER PTHR41521 1 98 3.3E-20 T 22-04-2016 TOLA_RS10110 509af9fb8c9c2bb07b5af7e5d392fcd2 99 SUPERFAMILY SSF54909 4 97 8.94E-27 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel TOLA_RS10110 509af9fb8c9c2bb07b5af7e5d392fcd2 99 Gene3D G3DSA:3.30.70.900 4 97 1.2E-31 T 22-04-2016 TOLA_RS10110 509af9fb8c9c2bb07b5af7e5d392fcd2 99 Pfam PF07045 Domain of unknown function (DUF1330) 4 97 5.0E-31 T 22-04-2016 IPR010753 Domain of unknown function DUF1330 TOLA_RS12205 638c60d35c8c3115f1ee7734a50954e9 186 Pfam PF11198 Protein of unknown function (DUF2857) 8 182 1.5E-59 T 22-04-2016 IPR021364 Protein of unknown function DUF2857 TOLA_RS04940 4db5ee62e51de3ab944f388d5b429c47 381 SMART SM00729 6 222 1.5E-50 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TOLA_RS04940 4db5ee62e51de3ab944f388d5b429c47 381 PANTHER PTHR13932 5 381 2.3E-205 T 22-04-2016 TOLA_RS04940 4db5ee62e51de3ab944f388d5b429c47 381 SUPERFAMILY SSF102114 5 379 4.32E-108 T 22-04-2016 TOLA_RS04940 4db5ee62e51de3ab944f388d5b429c47 381 Pfam PF04055 Radical SAM superfamily 11 175 2.4E-16 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS04940 4db5ee62e51de3ab944f388d5b429c47 381 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 371 3.7E-128 T 22-04-2016 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00071+1.3.99.-|KEGG: 00280+1.3.99.-|KEGG: 00281+1.3.99.-|KEGG: 00362+1.3.99.-|KEGG: 00626+1.3.99.-|KEGG: 00930+1.3.99.- TOLA_RS04940 4db5ee62e51de3ab944f388d5b429c47 381 Gene3D G3DSA:3.80.30.20 7 239 4.1E-25 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe TOLA_RS04940 4db5ee62e51de3ab944f388d5b429c47 381 PANTHER PTHR13932:SF7 5 381 2.3E-205 T 22-04-2016 TOLA_RS04940 4db5ee62e51de3ab944f388d5b429c47 381 Pfam PF06969 HemN C-terminal domain 307 367 7.0E-10 T 22-04-2016 IPR010723 HemN, C-terminal TOLA_RS12305 5921b7cedd20bdfa8e06c0edbbd35823 230 Pfam PF11679 Protein of unknown function (DUF3275) 13 220 7.8E-94 T 22-04-2016 IPR021693 Protein of unknown function DUF3275 TOLA_RS05310 c7bbe125e958f2258bfd519d59fededb 399 PANTHER PTHR30386 18 379 1.2E-156 T 22-04-2016 TOLA_RS05310 c7bbe125e958f2258bfd519d59fededb 399 Gene3D G3DSA:2.40.50.100 246 281 5.1E-18 T 22-04-2016 TOLA_RS05310 c7bbe125e958f2258bfd519d59fededb 399 Gene3D G3DSA:2.40.50.100 65 97 5.1E-18 T 22-04-2016 TOLA_RS05310 c7bbe125e958f2258bfd519d59fededb 399 PANTHER PTHR30386:SF6 18 379 1.2E-156 T 22-04-2016 TOLA_RS05310 c7bbe125e958f2258bfd519d59fededb 399 SUPERFAMILY SSF111369 58 121 7.32E-9 T 22-04-2016 TOLA_RS05310 c7bbe125e958f2258bfd519d59fededb 399 Pfam PF13533 Biotin-lipoyl like 66 111 1.7E-10 T 22-04-2016 TOLA_RS05310 c7bbe125e958f2258bfd519d59fededb 399 Pfam PF13437 HlyD family secretion protein 248 369 3.0E-15 T 22-04-2016 TOLA_RS05310 c7bbe125e958f2258bfd519d59fededb 399 SUPERFAMILY SSF111369 194 298 4.45E-10 T 22-04-2016 TOLA_RS05310 c7bbe125e958f2258bfd519d59fededb 399 SUPERFAMILY SSF111369 138 196 4.58E-5 T 22-04-2016 TOLA_RS11220 405997d23d74b1b383b8a83e37c02b9d 228 PANTHER PTHR30249:SF5 2 228 8.6E-80 T 22-04-2016 TOLA_RS11220 405997d23d74b1b383b8a83e37c02b9d 228 Pfam PF04172 LrgB-like family 10 222 2.8E-75 T 22-04-2016 IPR007300 CidB/LrgB family TOLA_RS11220 405997d23d74b1b383b8a83e37c02b9d 228 PANTHER PTHR30249 2 228 8.6E-80 T 22-04-2016 TOLA_RS00405 595c4fea82a37cd97e96e8672aa6d50d 186 PANTHER PTHR13061 5 179 1.4E-58 T 22-04-2016 TOLA_RS00405 595c4fea82a37cd97e96e8672aa6d50d 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 79 111 4.9E-6 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS00405 595c4fea82a37cd97e96e8672aa6d50d 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 44 5.3E-5 T 22-04-2016 IPR001451 Hexapeptide repeat TOLA_RS00405 595c4fea82a37cd97e96e8672aa6d50d 186 PANTHER PTHR13061:SF8 5 179 1.4E-58 T 22-04-2016 TOLA_RS00405 595c4fea82a37cd97e96e8672aa6d50d 186 Gene3D G3DSA:2.160.10.10 9 157 9.1E-36 T 22-04-2016 TOLA_RS00405 595c4fea82a37cd97e96e8672aa6d50d 186 SUPERFAMILY SSF51161 7 138 7.35E-31 T 22-04-2016 IPR011004 Trimeric LpxA-like TOLA_RS01295 8b12f1fb06214f7321b41fb92ac5c794 121 PANTHER PTHR40398 2 119 5.2E-36 T 22-04-2016 TOLA_RS01295 8b12f1fb06214f7321b41fb92ac5c794 121 Pfam PF03829 PTS system glucitol/sorbitol-specific IIA component 5 115 3.7E-39 T 22-04-2016 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS01295 8b12f1fb06214f7321b41fb92ac5c794 121 SUPERFAMILY SSF141530 3 118 4.45E-38 T 22-04-2016 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS01295 8b12f1fb06214f7321b41fb92ac5c794 121 Gene3D G3DSA:2.40.33.40 1 119 5.2E-43 T 22-04-2016 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS01295 8b12f1fb06214f7321b41fb92ac5c794 121 ProDom PD015842 PTS IIA COMPONENT GLUCITOL/SORBITOL-SPECIFIC SYSTEM ENZYME TRANSFERASE SYSTEM PHOSPHOTRANSFERASE EIIA 6 118 7.0E-31 T 22-04-2016 IPR004716 Phosphotransferase system, glucitol/sorbitol-specific IIA component GO:0005737|GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS04075 6dc403591f45851b42a9c26af305ff1e 412 TIGRFAM TIGR00901 2A0125: AmpG-like permease 26 364 2.3E-115 T 22-04-2016 IPR004752 AmpG-like permease/Acetyl-coenzyme A transporter 1 GO:0016020 TOLA_RS04075 6dc403591f45851b42a9c26af305ff1e 412 Pfam PF07690 Major Facilitator Superfamily 19 367 1.5E-21 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS04075 6dc403591f45851b42a9c26af305ff1e 412 PANTHER PTHR12778 3 400 3.4E-94 T 22-04-2016 TOLA_RS04075 6dc403591f45851b42a9c26af305ff1e 412 SUPERFAMILY SSF103473 5 408 6.93E-41 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS04075 6dc403591f45851b42a9c26af305ff1e 412 Gene3D G3DSA:1.20.1250.20 226 409 5.3E-16 T 22-04-2016 TOLA_RS04075 6dc403591f45851b42a9c26af305ff1e 412 Gene3D G3DSA:1.20.1250.20 13 199 4.3E-15 T 22-04-2016 TOLA_RS14860 23f03b73a9b62c8a012e4d0484d8ee03 240 PANTHER PTHR31527:SF0 3 232 1.6E-24 T 22-04-2016 TOLA_RS14860 23f03b73a9b62c8a012e4d0484d8ee03 240 TIGRFAM TIGR03425 urea_degr_2: urea carboxylase-associated protein 2 5 235 4.1E-97 T 22-04-2016 IPR017792 Urea carboxylase-associated protein 2 TOLA_RS14860 23f03b73a9b62c8a012e4d0484d8ee03 240 PANTHER PTHR31527 3 232 1.6E-24 T 22-04-2016 TOLA_RS14860 23f03b73a9b62c8a012e4d0484d8ee03 240 Pfam PF09347 Domain of unknown function (DUF1989) 10 180 9.9E-53 T 22-04-2016 IPR018959 Domain of unknown function DUF1989 TOLA_RS14725 59d12efd37f2851052ae84707170f196 105 Gene3D G3DSA:2.30.30.110 3 105 9.3E-35 T 22-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor TOLA_RS14725 59d12efd37f2851052ae84707170f196 105 ProDom PD012578 PLASMID TOXIN CCDB CYTOTOXIC LETB POST-SEGREGATION SYSTEM CCDB-LIKE GYRASE FUSED-CCDB 18 104 5.0E-36 T 22-04-2016 IPR002712 Toxin CcdB GO:0006276|GO:0008657 TOLA_RS14725 59d12efd37f2851052ae84707170f196 105 Pfam PF01845 CcdB protein 3 104 4.3E-33 T 22-04-2016 IPR002712 Toxin CcdB GO:0006276|GO:0008657 TOLA_RS14725 59d12efd37f2851052ae84707170f196 105 SUPERFAMILY SSF50118 3 105 1.37E-29 T 22-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor TOLA_RS08500 a5af5ef37ab02175494b34c1d7877882 263 Pfam PF06180 Cobalt chelatase (CbiK) 3 257 5.8E-98 T 22-04-2016 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 TOLA_RS08500 a5af5ef37ab02175494b34c1d7877882 263 PIRSF PIRSF033579 1 263 3.5E-103 T 22-04-2016 IPR010388 Anaerobic cobalt chelatase GO:0016852|GO:0019251 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 TOLA_RS08500 a5af5ef37ab02175494b34c1d7877882 263 Gene3D G3DSA:3.40.50.1400 1 150 6.6E-41 T 22-04-2016 TOLA_RS08500 a5af5ef37ab02175494b34c1d7877882 263 Gene3D G3DSA:3.40.50.1400 151 241 1.5E-22 T 22-04-2016 TOLA_RS08500 a5af5ef37ab02175494b34c1d7877882 263 SUPERFAMILY SSF53800 2 257 3.92E-81 T 22-04-2016 TOLA_RS08380 c04c463e7704b0a266b4ad48ca542caa 66 Pfam PF01361 Tautomerase enzyme 2 58 1.4E-19 T 22-04-2016 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 TOLA_RS08380 c04c463e7704b0a266b4ad48ca542caa 66 Gene3D G3DSA:3.30.429.20 1 60 2.7E-22 T 22-04-2016 TOLA_RS08380 c04c463e7704b0a266b4ad48ca542caa 66 SUPERFAMILY SSF55331 2 61 1.83E-18 T 22-04-2016 IPR014347 Tautomerase/MIF superfamily TOLA_RS08380 c04c463e7704b0a266b4ad48ca542caa 66 PANTHER PTHR35530 1 60 3.6E-14 T 22-04-2016 TOLA_RS08380 c04c463e7704b0a266b4ad48ca542caa 66 ProDom PD004816 MACROPHAGE MIGRATION INHIBITORY FACTOR TAUTOMERASE MIF PHENYLPYRUVATE CYTOKINE RESPONSE INFLAMMATORY 4 55 0.003 T 22-04-2016 IPR001398 Macrophage migration inhibitory factor TOLA_RS02030 713519a5d22d9c7f6d55b3964fbb8e63 437 PANTHER PTHR30026:SF3 5 434 4.8E-118 T 22-04-2016 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 TOLA_RS02030 713519a5d22d9c7f6d55b3964fbb8e63 437 Gene3D G3DSA:1.20.1600.10 20 426 6.5E-74 T 22-04-2016 TOLA_RS02030 713519a5d22d9c7f6d55b3964fbb8e63 437 PANTHER PTHR30026 5 434 4.8E-118 T 22-04-2016 TOLA_RS02030 713519a5d22d9c7f6d55b3964fbb8e63 437 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 20 431 1.1E-108 T 22-04-2016 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 TOLA_RS02030 713519a5d22d9c7f6d55b3964fbb8e63 437 Pfam PF02321 Outer membrane efflux protein 230 419 8.5E-31 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS02030 713519a5d22d9c7f6d55b3964fbb8e63 437 Pfam PF02321 Outer membrane efflux protein 24 206 1.6E-22 T 22-04-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 TOLA_RS02030 713519a5d22d9c7f6d55b3964fbb8e63 437 SUPERFAMILY SSF56954 1 424 7.32E-83 T 22-04-2016 TOLA_RS02980 dd9dd9bb5d91f7bb094e9db66f95b144 314 Pfam PF03747 ADP-ribosylglycohydrolase 10 274 8.4E-69 T 22-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 TOLA_RS02980 dd9dd9bb5d91f7bb094e9db66f95b144 314 SUPERFAMILY SSF101478 3 297 3.92E-75 T 22-04-2016 IPR005502 ADP-ribosylation/Crystallin J1 TOLA_RS02980 dd9dd9bb5d91f7bb094e9db66f95b144 314 PANTHER PTHR16222 5 297 7.9E-66 T 22-04-2016 TOLA_RS02980 dd9dd9bb5d91f7bb094e9db66f95b144 314 PANTHER PTHR16222:SF12 5 297 7.9E-66 T 22-04-2016 TOLA_RS09675 7de14c6c2830938a8660cbaaca2ea106 354 Pfam PF02378 Phosphotransferase system, EIIC 17 279 1.6E-11 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS09675 7de14c6c2830938a8660cbaaca2ea106 354 PANTHER PTHR30505 1 354 1.3E-144 T 22-04-2016 TOLA_RS09675 7de14c6c2830938a8660cbaaca2ea106 354 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 9 332 9.3E-86 T 22-04-2016 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 TOLA_RS09675 7de14c6c2830938a8660cbaaca2ea106 354 PANTHER PTHR30505:SF1 1 354 1.3E-144 T 22-04-2016 TOLA_RS06290 72af1d69d011b1c0ea5f58f8a2d79b45 250 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS06290 72af1d69d011b1c0ea5f58f8a2d79b45 250 Pfam PF00005 ABC transporter 25 173 2.8E-38 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS06290 72af1d69d011b1c0ea5f58f8a2d79b45 250 PANTHER PTHR24220:SF490 11 250 7.0E-176 T 22-04-2016 TOLA_RS06290 72af1d69d011b1c0ea5f58f8a2d79b45 250 PANTHER PTHR24220 11 250 7.0E-176 T 22-04-2016 TOLA_RS06290 72af1d69d011b1c0ea5f58f8a2d79b45 250 SMART SM00382 34 221 1.1E-13 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS06290 72af1d69d011b1c0ea5f58f8a2d79b45 250 SUPERFAMILY SSF52540 9 241 4.15E-81 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06290 72af1d69d011b1c0ea5f58f8a2d79b45 250 Gene3D G3DSA:3.40.50.300 9 244 1.6E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06290 72af1d69d011b1c0ea5f58f8a2d79b45 250 PIRSF PIRSF039085 6 249 1.4E-109 T 22-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TOLA_RS09085 6349ee302013262708f2412d99af8089 301 Gene3D G3DSA:1.10.10.10 6 79 5.4E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09085 6349ee302013262708f2412d99af8089 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.3E-14 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS09085 6349ee302013262708f2412d99af8089 301 SUPERFAMILY SSF46785 6 83 5.46E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS09085 6349ee302013262708f2412d99af8089 301 PANTHER PTHR30537 1 297 8.8E-66 T 22-04-2016 TOLA_RS09085 6349ee302013262708f2412d99af8089 301 Pfam PF03466 LysR substrate binding domain 91 293 1.3E-33 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS09085 6349ee302013262708f2412d99af8089 301 Gene3D G3DSA:3.40.190.10 95 178 4.8E-20 T 22-04-2016 TOLA_RS09085 6349ee302013262708f2412d99af8089 301 SUPERFAMILY SSF53850 91 296 5.74E-35 T 22-04-2016 TOLA_RS09085 6349ee302013262708f2412d99af8089 301 Gene3D G3DSA:3.40.190.10 179 262 6.9E-13 T 22-04-2016 TOLA_RS05190 644e2f041ae9999c8647f2ab0741f805 142 PIRSF PIRSF016789 5 127 7.7E-45 T 22-04-2016 IPR007401 Protein of unknown function DUF454 TOLA_RS05190 644e2f041ae9999c8647f2ab0741f805 142 Pfam PF04304 Protein of unknown function (DUF454) 6 121 2.4E-43 T 22-04-2016 IPR007401 Protein of unknown function DUF454 TOLA_RS05190 644e2f041ae9999c8647f2ab0741f805 142 PANTHER PTHR35813 1 129 5.8E-45 T 22-04-2016 TOLA_RS05190 644e2f041ae9999c8647f2ab0741f805 142 PANTHER PTHR35813:SF1 1 129 5.8E-45 T 22-04-2016 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 SUPERFAMILY SSF53748 3 383 2.59E-144 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 383 38.764 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 6.8E-82 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 PRINTS PR00477 Phosphoglycerate kinase family signature 359 376 6.8E-82 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 PRINTS PR00477 Phosphoglycerate kinase family signature 336 347 6.8E-82 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 6.8E-82 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 6.8E-82 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 6.8E-82 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 6.8E-82 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 6.8E-82 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 PRINTS PR00477 Phosphoglycerate kinase family signature 303 328 6.8E-82 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 Gene3D G3DSA:3.40.50.1270 175 371 2.4E-80 T 22-04-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 PANTHER PTHR11406 1 387 1.5E-196 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 Gene3D G3DSA:3.40.50.1260 5 174 2.5E-63 T 22-04-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 22-04-2016 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 Pfam PF00162 Phosphoglycerate kinase 6 373 8.3E-137 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS06425 943172eb81a7363f4f42eb69efbbc431 387 PIRSF PIRSF000724 1 387 1.3E-133 T 22-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 TOLA_RS13110 aeff4a00e42f6b9fe42c0e12da4992f4 386 PANTHER PTHR33744 5 384 1.5E-150 T 22-04-2016 TOLA_RS13110 aeff4a00e42f6b9fe42c0e12da4992f4 386 PANTHER PTHR33744:SF1 5 384 1.5E-150 T 22-04-2016 TOLA_RS13110 aeff4a00e42f6b9fe42c0e12da4992f4 386 Pfam PF13556 PucR C-terminal helix-turn-helix domain 323 382 3.3E-21 T 22-04-2016 IPR025736 PucR C-terminal helix-turn-helix domain TOLA_RS13110 aeff4a00e42f6b9fe42c0e12da4992f4 386 Gene3D G3DSA:1.10.10.60 339 358 2.3E-5 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS13110 aeff4a00e42f6b9fe42c0e12da4992f4 386 Pfam PF05651 Putative sugar diacid recognition 6 138 1.2E-49 T 22-04-2016 IPR008599 Putative sugar diacid recognition TOLA_RS07450 94317bdca03e3d0fceb9d043ba14ead2 445 Pfam PF03882 MukF winged-helix domain 9 120 8.7E-50 T 22-04-2016 IPR033439 Chromosome partition protein MukF, winged-helix domain TOLA_RS07450 94317bdca03e3d0fceb9d043ba14ead2 445 SUPERFAMILY SSF140570 123 285 9.94E-61 T 22-04-2016 IPR033440 Chromosome partition protein MukF, middle domain TOLA_RS07450 94317bdca03e3d0fceb9d043ba14ead2 445 Pfam PF17192 MukF middle domain 125 285 2.6E-74 T 22-04-2016 IPR033440 Chromosome partition protein MukF, middle domain TOLA_RS07450 94317bdca03e3d0fceb9d043ba14ead2 445 SUPERFAMILY SSF46785 12 120 1.41E-35 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07450 94317bdca03e3d0fceb9d043ba14ead2 445 Pfam PF17193 MukF C-terminal domain 287 445 6.6E-75 T 22-04-2016 IPR033441 Chromosome partition protein MukF, C-terminal domain TOLA_RS07450 94317bdca03e3d0fceb9d043ba14ead2 445 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 78 - T 22-04-2016 IPR010916 TonB box, conserved site TOLA_RS07450 94317bdca03e3d0fceb9d043ba14ead2 445 Gene3D G3DSA:1.10.10.10 27 121 1.1E-35 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS16375 78470cf7815f9255796de9e7132a6afc 143 Gene3D G3DSA:3.40.630.30 1 140 3.1E-18 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS16375 78470cf7815f9255796de9e7132a6afc 143 SUPERFAMILY SSF55729 1 139 5.68E-17 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS16375 78470cf7815f9255796de9e7132a6afc 143 Pfam PF13508 Acetyltransferase (GNAT) domain 50 121 3.3E-9 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS15645 d941a8e1af7d880a4465b67ee29f9360 207 Gene3D G3DSA:3.20.20.70 2 206 4.1E-77 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS15645 d941a8e1af7d880a4465b67ee29f9360 207 Pfam PF01081 KDPG and KHG aldolase 6 198 6.5E-70 T 22-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TOLA_RS15645 d941a8e1af7d880a4465b67ee29f9360 207 PANTHER PTHR30246:SF5 1 203 1.5E-115 T 22-04-2016 TOLA_RS15645 d941a8e1af7d880a4465b67ee29f9360 207 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 36 45 - T 22-04-2016 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562|UniPathway: UPA00227|UniPathway: UPA00856 TOLA_RS15645 d941a8e1af7d880a4465b67ee29f9360 207 PANTHER PTHR30246 1 203 1.5E-115 T 22-04-2016 TOLA_RS15645 d941a8e1af7d880a4465b67ee29f9360 207 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 6 204 1.4E-81 T 22-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TOLA_RS15645 d941a8e1af7d880a4465b67ee29f9360 207 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 124 137 - T 22-04-2016 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 TOLA_RS15645 d941a8e1af7d880a4465b67ee29f9360 207 SUPERFAMILY SSF51569 3 205 1.06E-66 T 22-04-2016 TOLA_RS15920 f1cfbd300bd4f0220d7cc3de8702cdb1 109 PIRSF PIRSF000699 1 105 4.4E-32 T 22-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15920 f1cfbd300bd4f0220d7cc3de8702cdb1 109 Gene3D G3DSA:1.20.58.80 2 99 5.7E-38 T 22-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15920 f1cfbd300bd4f0220d7cc3de8702cdb1 109 PANTHER PTHR34382:SF2 1 106 1.7E-37 T 22-04-2016 TOLA_RS15920 f1cfbd300bd4f0220d7cc3de8702cdb1 109 SUPERFAMILY SSF46973 1 98 2.22E-34 T 22-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15920 f1cfbd300bd4f0220d7cc3de8702cdb1 109 PANTHER PTHR34382 1 106 1.7E-37 T 22-04-2016 TOLA_RS15920 f1cfbd300bd4f0220d7cc3de8702cdb1 109 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 6 98 1.4E-33 T 22-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS15360 1f4ebcc5271ab3a6e96f2a6576e998e5 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 1.4E-24 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS15360 1f4ebcc5271ab3a6e96f2a6576e998e5 101 PANTHER PTHR34581 2 101 1.9E-44 T 22-04-2016 TOLA_RS15360 1f4ebcc5271ab3a6e96f2a6576e998e5 101 Gene3D G3DSA:3.40.50.270 1 101 1.4E-39 T 22-04-2016 TOLA_RS15360 1f4ebcc5271ab3a6e96f2a6576e998e5 101 PANTHER PTHR34581:SF2 2 101 1.9E-44 T 22-04-2016 TOLA_RS15360 1f4ebcc5271ab3a6e96f2a6576e998e5 101 SUPERFAMILY SSF52794 1 101 1.46E-36 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS09115 c91bf8609f6aa5fe8e608532f4d12748 602 PANTHER PTHR21000:SF9 1 596 0.0 T 22-04-2016 TOLA_RS09115 c91bf8609f6aa5fe8e608532f4d12748 602 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 2 596 6.1E-265 T 22-04-2016 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12|UniPathway: UPA00226 TOLA_RS09115 c91bf8609f6aa5fe8e608532f4d12748 602 PANTHER PTHR21000 1 596 0.0 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS09115 c91bf8609f6aa5fe8e608532f4d12748 602 SUPERFAMILY SSF143975 1 416 6.41E-134 T 22-04-2016 TOLA_RS09115 c91bf8609f6aa5fe8e608532f4d12748 602 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 503 514 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS09115 c91bf8609f6aa5fe8e608532f4d12748 602 Pfam PF00920 Dehydratase family 66 593 1.5E-149 T 22-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS09115 c91bf8609f6aa5fe8e608532f4d12748 602 SUPERFAMILY SSF52016 417 597 1.8E-53 T 22-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel TOLA_RS09115 c91bf8609f6aa5fe8e608532f4d12748 602 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 154 164 - T 22-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 TOLA_RS04650 bd270dab6247b21389e821076dc24a46 305 Pfam PF01963 TraB family 42 300 1.7E-60 T 22-04-2016 IPR002816 Pheromone shutdown, TraB TOLA_RS04650 bd270dab6247b21389e821076dc24a46 305 PANTHER PTHR40590 15 302 2.1E-41 T 22-04-2016 TOLA_RS05560 8b9a1367f249cd0f53b03006ee5b268e 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 7.1E-32 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS05560 8b9a1367f249cd0f53b03006ee5b268e 90 SMART SM00411 1 90 9.0E-41 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS05560 8b9a1367f249cd0f53b03006ee5b268e 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.9E-18 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS05560 8b9a1367f249cd0f53b03006ee5b268e 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.9E-18 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS05560 8b9a1367f249cd0f53b03006ee5b268e 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.9E-18 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS05560 8b9a1367f249cd0f53b03006ee5b268e 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 22-04-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 TOLA_RS05560 8b9a1367f249cd0f53b03006ee5b268e 90 SUPERFAMILY SSF47729 1 90 3.24E-30 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 TOLA_RS05560 8b9a1367f249cd0f53b03006ee5b268e 90 Gene3D G3DSA:4.10.520.10 1 90 1.2E-35 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 TOLA_RS05560 8b9a1367f249cd0f53b03006ee5b268e 90 PANTHER PTHR33175 1 90 1.7E-41 T 22-04-2016 TOLA_RS09255 e868c893861208331e6581d702639822 247 PANTHER PTHR19370 4 231 1.3E-75 T 22-04-2016 TOLA_RS09255 e868c893861208331e6581d702639822 247 SUPERFAMILY SSF52343 103 247 2.49E-35 T 22-04-2016 TOLA_RS09255 e868c893861208331e6581d702639822 247 Pfam PF00175 Oxidoreductase NAD-binding domain 111 221 9.6E-17 T 22-04-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TOLA_RS09255 e868c893861208331e6581d702639822 247 Pfam PF00970 Oxidoreductase FAD-binding domain 13 90 1.2E-7 T 22-04-2016 IPR008333 Oxidoreductase, FAD-binding domain TOLA_RS09255 e868c893861208331e6581d702639822 247 SUPERFAMILY SSF63380 3 97 7.17E-23 T 22-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TOLA_RS09255 e868c893861208331e6581d702639822 247 Gene3D G3DSA:3.40.50.80 97 247 2.4E-41 T 22-04-2016 TOLA_RS09255 e868c893861208331e6581d702639822 247 Gene3D G3DSA:2.40.30.10 2 96 1.2E-24 T 22-04-2016 TOLA_RS09255 e868c893861208331e6581d702639822 247 PANTHER PTHR19370:SF98 4 231 1.3E-75 T 22-04-2016 TOLA_RS04860 0b739af57c396254026d145a0890988e 348 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 105 119 - T 22-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 TOLA_RS04860 0b739af57c396254026d145a0890988e 348 SUPERFAMILY SSF55120 67 231 6.72E-44 T 22-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS04860 0b739af57c396254026d145a0890988e 348 Pfam PF00849 RNA pseudouridylate synthase 67 197 2.1E-17 T 22-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TOLA_RS04860 0b739af57c396254026d145a0890988e 348 Gene3D G3DSA:3.10.290.10 3 57 1.2E-17 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS04860 0b739af57c396254026d145a0890988e 348 SUPERFAMILY SSF55174 5 97 3.24E-18 T 22-04-2016 TOLA_RS04860 0b739af57c396254026d145a0890988e 348 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 71 231 3.8E-59 T 22-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 TOLA_RS04860 0b739af57c396254026d145a0890988e 348 PANTHER PTHR21600:SF2 1 308 4.4E-102 T 22-04-2016 TOLA_RS04860 0b739af57c396254026d145a0890988e 348 SMART SM00363 3 65 7.3E-11 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS04860 0b739af57c396254026d145a0890988e 348 Pfam PF01479 S4 domain 4 48 2.6E-13 T 22-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 TOLA_RS04860 0b739af57c396254026d145a0890988e 348 PANTHER PTHR21600 1 308 4.4E-102 T 22-04-2016 TOLA_RS11205 6f70c798fab560881ef3968b7e4e1537 331 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 8 326 2.6E-113 T 22-04-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 TOLA_RS11205 6f70c798fab560881ef3968b7e4e1537 331 PANTHER PTHR11409 1 331 7.2E-162 T 22-04-2016 TOLA_RS11205 6f70c798fab560881ef3968b7e4e1537 331 SUPERFAMILY SSF51556 4 327 1.05E-88 T 22-04-2016 IPR032466 Metal-dependent hydrolase TOLA_RS11205 6f70c798fab560881ef3968b7e4e1537 331 Pfam PF00962 Adenosine/AMP deaminase 8 324 7.8E-73 T 22-04-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 TOLA_RS11205 6f70c798fab560881ef3968b7e4e1537 331 Gene3D G3DSA:3.20.20.140 4 327 1.6E-101 T 22-04-2016 TOLA_RS11205 6f70c798fab560881ef3968b7e4e1537 331 Hamap MF_01962 Adenine deaminase. 4 316 84.97 T 22-04-2016 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 TOLA_RS11205 6f70c798fab560881ef3968b7e4e1537 331 PANTHER PTHR11409:SF41 1 331 7.2E-162 T 22-04-2016 TOLA_RS14760 e879f655fd3c70ff8679b92f4f91d57a 127 PANTHER PTHR10584 6 67 5.5E-15 T 22-04-2016 TOLA_RS14760 e879f655fd3c70ff8679b92f4f91d57a 127 Pfam PF04241 Protein of unknown function (DUF423) 20 106 1.1E-28 T 22-04-2016 IPR006696 Protein of unknown function DUF423 TOLA_RS14760 e879f655fd3c70ff8679b92f4f91d57a 127 PANTHER PTHR10584:SF191 6 67 5.5E-15 T 22-04-2016 TOLA_RS00310 2285d6300d8cb19bf08be64ddffdfb6b 82 PIRSF PIRSF002855 1 82 2.5E-20 T 22-04-2016 IPR016367 Murein-lipoprotein TOLA_RS00310 2285d6300d8cb19bf08be64ddffdfb6b 82 PANTHER PTHR38763 1 82 4.2E-13 T 22-04-2016 TOLA_RS00310 2285d6300d8cb19bf08be64ddffdfb6b 82 Pfam PF04728 Lipoprotein leucine-zipper 25 82 2.2E-16 T 22-04-2016 IPR006817 Lipoprotein leucine-zipper GO:0019867 TOLA_RS00310 2285d6300d8cb19bf08be64ddffdfb6b 82 SUPERFAMILY SSF58042 20 81 1.2E-15 T 22-04-2016 TOLA_RS01695 55bc62fd4570a14465622cadcd551727 153 Pfam PF00210 Ferritin-like domain 17 153 2.1E-30 T 22-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TOLA_RS01695 55bc62fd4570a14465622cadcd551727 153 Gene3D G3DSA:1.20.1260.10 1 153 3.0E-62 T 22-04-2016 IPR012347 Ferritin-related TOLA_RS01695 55bc62fd4570a14465622cadcd551727 153 PANTHER PTHR30295:SF6 3 153 9.8E-63 T 22-04-2016 TOLA_RS01695 55bc62fd4570a14465622cadcd551727 153 PANTHER PTHR30295 3 153 9.8E-63 T 22-04-2016 TOLA_RS01695 55bc62fd4570a14465622cadcd551727 153 ProSitePatterns PS00819 Dps protein family signature 2. 61 75 - T 22-04-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 TOLA_RS01695 55bc62fd4570a14465622cadcd551727 153 ProSitePatterns PS00818 Dps protein family signature 1. 35 51 - T 22-04-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 TOLA_RS01695 55bc62fd4570a14465622cadcd551727 153 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 35 51 1.6E-10 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 TOLA_RS01695 55bc62fd4570a14465622cadcd551727 153 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 130 148 1.6E-10 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 TOLA_RS01695 55bc62fd4570a14465622cadcd551727 153 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 59 75 1.6E-10 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 TOLA_RS01695 55bc62fd4570a14465622cadcd551727 153 SUPERFAMILY SSF47240 3 153 1.25E-46 T 22-04-2016 IPR009078 Ferritin-like superfamily TOLA_RS01695 55bc62fd4570a14465622cadcd551727 153 PIRSF PIRSF005900 1 153 9.0E-45 T 22-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 TOLA_RS06885 501f75d30b677fcb29c429b80f3263b9 365 Pfam PF01594 Domain of unknown function DUF20 17 345 3.4E-41 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like TOLA_RS06885 501f75d30b677fcb29c429b80f3263b9 365 PANTHER PTHR21716 8 348 1.1E-58 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like TOLA_RS06885 501f75d30b677fcb29c429b80f3263b9 365 PANTHER PTHR21716:SF20 8 348 1.1E-58 T 22-04-2016 TOLA_RS06155 092490fbbfdf6dd68151f8c933a640a4 174 PANTHER PTHR36570:SF2 1 170 1.3E-56 T 22-04-2016 TOLA_RS06155 092490fbbfdf6dd68151f8c933a640a4 174 Pfam PF02600 Disulfide bond formation protein DsbB 12 160 1.0E-40 T 22-04-2016 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 TOLA_RS06155 092490fbbfdf6dd68151f8c933a640a4 174 PANTHER PTHR36570 1 170 1.3E-56 T 22-04-2016 TOLA_RS06155 092490fbbfdf6dd68151f8c933a640a4 174 SUPERFAMILY SSF158442 15 161 9.68E-40 T 22-04-2016 TOLA_RS06155 092490fbbfdf6dd68151f8c933a640a4 174 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 7 168 19.927 T 22-04-2016 IPR022920 Disulphide bond formation protein DsbB TOLA_RS06155 092490fbbfdf6dd68151f8c933a640a4 174 Gene3D G3DSA:1.20.1550.10 4 168 1.5E-55 T 22-04-2016 IPR023380 Disulphide bond formation protein DsbB-like domain TOLA_RS03385 b9dc93f847cf569287381bb066730796 151 SUPERFAMILY SSF53146 14 128 2.22E-27 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS03385 b9dc93f847cf569287381bb066730796 151 Gene3D G3DSA:3.30.420.130 13 132 3.1E-31 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS03385 b9dc93f847cf569287381bb066730796 151 PANTHER PTHR33937 18 120 2.9E-15 T 22-04-2016 TOLA_RS03385 b9dc93f847cf569287381bb066730796 151 PANTHER PTHR33937:SF1 18 120 2.9E-15 T 22-04-2016 TOLA_RS03385 b9dc93f847cf569287381bb066730796 151 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 28 119 2.1E-16 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS11970 ddb89c9cb038c236c8de56354205adf9 217 SUPERFAMILY SSF56935 15 217 4.76E-5 T 22-04-2016 TOLA_RS11970 ddb89c9cb038c236c8de56354205adf9 217 TIGRFAM TIGR04219 OMP_w_GlyGly: outer membrane protein 4 217 2.5E-60 T 22-04-2016 IPR026387 Outer membrane protein TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 PRINTS PR00084 Mannitol dehydrogenase signature 222 235 1.5E-17 T 22-04-2016 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 PRINTS PR00084 Mannitol dehydrogenase signature 183 196 1.5E-17 T 22-04-2016 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 PRINTS PR00084 Mannitol dehydrogenase signature 31 41 1.5E-17 T 22-04-2016 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 PRINTS PR00084 Mannitol dehydrogenase signature 252 267 1.5E-17 T 22-04-2016 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0008152|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 ProSitePatterns PS00974 Mannitol dehydrogenases signature. 222 234 - T 22-04-2016 IPR023027 Mannitol dehydrogenase, conserved site GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 221 466 5.3E-89 T 22-04-2016 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 SUPERFAMILY SSF51735 10 285 9.45E-92 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 PANTHER PTHR30562:SF7 1 491 3.9E-228 T 22-04-2016 TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 Gene3D G3DSA:3.40.50.720 10 285 1.1E-105 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 Gene3D G3DSA:1.10.1040.10 286 490 2.1E-71 T 22-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 SUPERFAMILY SSF48179 287 490 1.9E-64 T 22-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 PANTHER PTHR30562 1 491 3.9E-228 T 22-04-2016 TOLA_RS14770 926ad130533b6dc7b7b9c24fb1c1d490 491 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 30 192 2.6E-44 T 22-04-2016 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 TOLA_RS01640 a115a2c2bdac4bb1dd3527eae031ed6b 181 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 9 96 1.3E-10 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS01640 a115a2c2bdac4bb1dd3527eae031ed6b 181 SUPERFAMILY SSF53146 1 103 1.7E-16 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS01640 a115a2c2bdac4bb1dd3527eae031ed6b 181 Gene3D G3DSA:3.30.420.130 1 98 1.6E-16 T 22-04-2016 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TOLA_RS08120 22d2924c2253f81f89b7b3788ba5825c 680 Pfam PF13476 AAA domain 6 251 6.4E-12 T 22-04-2016 TOLA_RS08120 22d2924c2253f81f89b7b3788ba5825c 680 Gene3D G3DSA:3.40.1140.10 553 630 4.4E-20 T 22-04-2016 TOLA_RS08120 22d2924c2253f81f89b7b3788ba5825c 680 Gene3D G3DSA:3.40.1140.10 1 102 4.4E-20 T 22-04-2016 TOLA_RS08120 22d2924c2253f81f89b7b3788ba5825c 680 SUPERFAMILY SSF52540 1 315 2.15E-18 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08120 22d2924c2253f81f89b7b3788ba5825c 680 SUPERFAMILY SSF52540 1 56 7.63E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08120 22d2924c2253f81f89b7b3788ba5825c 680 SUPERFAMILY SSF52540 412 626 7.63E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09925 94ea0e387d7f305197cf993eb0766cdb 479 Gene3D G3DSA:3.40.50.980 3 140 7.1E-24 T 22-04-2016 TOLA_RS09925 94ea0e387d7f305197cf993eb0766cdb 479 Gene3D G3DSA:3.40.50.980 141 309 1.5E-26 T 22-04-2016 TOLA_RS09925 94ea0e387d7f305197cf993eb0766cdb 479 Gene3D G3DSA:2.30.38.10 320 365 1.5E-4 T 22-04-2016 TOLA_RS09925 94ea0e387d7f305197cf993eb0766cdb 479 SUPERFAMILY SSF56801 2 473 1.18E-82 T 22-04-2016 TOLA_RS09925 94ea0e387d7f305197cf993eb0766cdb 479 Gene3D G3DSA:3.30.300.30 369 463 5.2E-4 T 22-04-2016 TOLA_RS09925 94ea0e387d7f305197cf993eb0766cdb 479 Pfam PF00501 AMP-binding enzyme 9 368 1.9E-56 T 22-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 TOLA_RS09925 94ea0e387d7f305197cf993eb0766cdb 479 ProSitePatterns PS00455 Putative AMP-binding domain signature. 135 146 - T 22-04-2016 IPR020845 AMP-binding, conserved site TOLA_RS09925 94ea0e387d7f305197cf993eb0766cdb 479 PANTHER PTHR24096 1 444 6.1E-66 T 22-04-2016 TOLA_RS14750 775723aae82ea39e5ddf121b19cbf230 198 PIRSF PIRSF020606 1 197 2.2E-75 T 22-04-2016 IPR014509 Uncharacterised conserved protein UCP020606 TOLA_RS14750 775723aae82ea39e5ddf121b19cbf230 198 Pfam PF09997 Predicted membrane protein (DUF2238) 35 175 1.4E-56 T 22-04-2016 IPR014509 Uncharacterised conserved protein UCP020606 TOLA_RS06915 c5bb4a790bb03ccdd37f02e08eb16e23 414 PANTHER PTHR30489 87 413 5.2E-54 T 22-04-2016 TOLA_RS06915 c5bb4a790bb03ccdd37f02e08eb16e23 414 PANTHER PTHR30489 1 60 5.2E-54 T 22-04-2016 TOLA_RS06915 c5bb4a790bb03ccdd37f02e08eb16e23 414 Pfam PF12704 MacB-like periplasmic core domain 19 254 1.9E-19 T 22-04-2016 IPR025857 MacB-like periplasmic core domain TOLA_RS06915 c5bb4a790bb03ccdd37f02e08eb16e23 414 Pfam PF02687 FtsX-like permease family 285 401 4.8E-17 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 TOLA_RS09005 136153bf4072feaee1f8c1538c3c4f01 454 SUPERFAMILY SSF53850 33 123 4.19E-19 T 22-04-2016 TOLA_RS09005 136153bf4072feaee1f8c1538c3c4f01 454 SUPERFAMILY SSF53850 159 347 4.19E-19 T 22-04-2016 TOLA_RS09005 136153bf4072feaee1f8c1538c3c4f01 454 PANTHER PTHR30024:SF7 163 433 4.5E-129 T 22-04-2016 TOLA_RS09005 136153bf4072feaee1f8c1538c3c4f01 454 PANTHER PTHR30024:SF7 1 137 4.5E-129 T 22-04-2016 TOLA_RS09005 136153bf4072feaee1f8c1538c3c4f01 454 PANTHER PTHR30024 163 433 4.5E-129 T 22-04-2016 TOLA_RS09005 136153bf4072feaee1f8c1538c3c4f01 454 PANTHER PTHR30024 1 137 4.5E-129 T 22-04-2016 TOLA_RS09005 136153bf4072feaee1f8c1538c3c4f01 454 Pfam PF13379 NMT1-like family 28 308 1.1E-102 T 22-04-2016 TOLA_RS14585 f4df44dddaace2b53bcaccdbaa5ed8b3 100 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 92 6.2E-18 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TOLA_RS14585 f4df44dddaace2b53bcaccdbaa5ed8b3 100 PANTHER PTHR33755 1 97 3.9E-42 T 22-04-2016 TOLA_RS14585 f4df44dddaace2b53bcaccdbaa5ed8b3 100 PANTHER PTHR33755:SF5 1 97 3.9E-42 T 22-04-2016 TOLA_RS06140 850e49f99b293692c99b4400a86abb76 251 Pfam PF13531 Bacterial extracellular solute-binding protein 27 249 8.5E-46 T 22-04-2016 TOLA_RS06140 850e49f99b293692c99b4400a86abb76 251 Gene3D G3DSA:3.40.190.10 116 210 2.3E-36 T 22-04-2016 TOLA_RS06140 850e49f99b293692c99b4400a86abb76 251 Gene3D G3DSA:3.40.190.10 24 115 7.1E-13 T 22-04-2016 TOLA_RS06140 850e49f99b293692c99b4400a86abb76 251 Gene3D G3DSA:3.40.190.10 211 249 7.1E-13 T 22-04-2016 TOLA_RS06140 850e49f99b293692c99b4400a86abb76 251 PANTHER PTHR30632:SF0 23 250 3.2E-38 T 22-04-2016 TOLA_RS06140 850e49f99b293692c99b4400a86abb76 251 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 31 248 3.1E-73 T 22-04-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 TOLA_RS06140 850e49f99b293692c99b4400a86abb76 251 PIRSF PIRSF004846 6 251 1.1E-53 T 22-04-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 TOLA_RS06140 850e49f99b293692c99b4400a86abb76 251 PANTHER PTHR30632 23 250 3.2E-38 T 22-04-2016 TOLA_RS06140 850e49f99b293692c99b4400a86abb76 251 SUPERFAMILY SSF53850 24 250 4.18E-58 T 22-04-2016 TOLA_RS14090 9d8f1d63eca51443163de42f14dfa1e5 441 Pfam PF07690 Major Facilitator Superfamily 66 374 7.6E-24 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS14090 9d8f1d63eca51443163de42f14dfa1e5 441 PANTHER PTHR23508 15 426 1.0E-232 T 22-04-2016 TOLA_RS14090 9d8f1d63eca51443163de42f14dfa1e5 441 Gene3D G3DSA:1.20.1250.20 257 432 3.9E-13 T 22-04-2016 TOLA_RS14090 9d8f1d63eca51443163de42f14dfa1e5 441 SUPERFAMILY SSF103473 20 432 1.31E-60 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS14090 9d8f1d63eca51443163de42f14dfa1e5 441 Gene3D G3DSA:1.20.1250.20 23 229 1.3E-19 T 22-04-2016 TOLA_RS14090 9d8f1d63eca51443163de42f14dfa1e5 441 PANTHER PTHR23508:SF5 15 426 1.0E-232 T 22-04-2016 TOLA_RS14440 94e242865c04d852acbf11690de30053 576 PANTHER PTHR32234 35 575 3.1E-155 T 22-04-2016 TOLA_RS14440 94e242865c04d852acbf11690de30053 576 PANTHER PTHR32234:SF0 35 575 3.1E-155 T 22-04-2016 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 TOLA_RS14440 94e242865c04d852acbf11690de30053 576 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 1 571 32.256 T 22-04-2016 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 TOLA_RS14440 94e242865c04d852acbf11690de30053 576 Pfam PF11412 Disulphide bond corrector protein DsbC 36 145 2.6E-26 T 22-04-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain TOLA_RS14440 94e242865c04d852acbf11690de30053 576 Gene3D G3DSA:2.60.40.1250 33 147 2.0E-35 T 22-04-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain TOLA_RS14440 94e242865c04d852acbf11690de30053 576 SUPERFAMILY SSF74863 35 146 1.57E-31 T 22-04-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain TOLA_RS14440 94e242865c04d852acbf11690de30053 576 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 184 388 3.4E-15 T 22-04-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 TOLA_RS14440 94e242865c04d852acbf11690de30053 576 SUPERFAMILY SSF52833 453 569 1.52E-20 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS14440 94e242865c04d852acbf11690de30053 576 Gene3D G3DSA:3.40.30.10 458 570 2.0E-30 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS14440 94e242865c04d852acbf11690de30053 576 ProSitePatterns PS00194 Thioredoxin family active site. 479 497 - T 22-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 TOLA_RS14440 94e242865c04d852acbf11690de30053 576 Pfam PF13899 Thioredoxin-like 463 544 4.3E-13 T 22-04-2016 TOLA_RS03185 aa0cb41fdb745464ca996d271f63ffcc 308 PANTHER PTHR11135 1 290 1.1E-138 T 22-04-2016 TOLA_RS03185 aa0cb41fdb745464ca996d271f63ffcc 308 SMART SM00729 23 247 1.9E-38 T 22-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TOLA_RS03185 aa0cb41fdb745464ca996d271f63ffcc 308 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 6 300 3.5E-129 T 22-04-2016 IPR005911 Protein YhcC-like GO:0051536 TOLA_RS03185 aa0cb41fdb745464ca996d271f63ffcc 308 Gene3D G3DSA:3.80.30.20 23 252 1.2E-32 T 22-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe TOLA_RS03185 aa0cb41fdb745464ca996d271f63ffcc 308 SUPERFAMILY SSF102114 13 255 5.49E-45 T 22-04-2016 TOLA_RS03185 aa0cb41fdb745464ca996d271f63ffcc 308 PANTHER PTHR11135:SF1 1 290 1.1E-138 T 22-04-2016 IPR005911 Protein YhcC-like GO:0051536 TOLA_RS03185 aa0cb41fdb745464ca996d271f63ffcc 308 Pfam PF04055 Radical SAM superfamily 43 201 1.7E-12 T 22-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TOLA_RS03185 aa0cb41fdb745464ca996d271f63ffcc 308 Pfam PF16199 Radical_SAM C-terminal domain 209 288 3.8E-22 T 22-04-2016 IPR032432 Radical SAM, C-terminal extension TOLA_RS00735 34494e64fc147bc55898a1db3b4cefa6 106 SMART SM00450 7 102 8.1E-19 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS00735 34494e64fc147bc55898a1db3b4cefa6 106 Pfam PF00581 Rhodanese-like domain 11 97 9.8E-14 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS00735 34494e64fc147bc55898a1db3b4cefa6 106 SUPERFAMILY SSF52821 1 101 6.42E-27 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS00735 34494e64fc147bc55898a1db3b4cefa6 106 Gene3D G3DSA:3.40.250.10 2 99 8.6E-27 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS00735 34494e64fc147bc55898a1db3b4cefa6 106 Hamap MF_01009 Thiosulfate sulfurtransferase GlpE [glpE]. 2 106 29.538 T 22-04-2016 IPR023695 Thiosulfate sulfurtransferase, bacterial GO:0004792|GO:0005737 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 TOLA_RS06630 1807c18533769bdc41cf0453bdd50d3b 209 PIRSF PIRSF006324 1 207 2.5E-51 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS06630 1807c18533769bdc41cf0453bdd50d3b 209 PANTHER PTHR30086 1 209 2.3E-86 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS06630 1807c18533769bdc41cf0453bdd50d3b 209 Pfam PF01810 LysE type translocator 16 202 5.9E-32 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS06630 1807c18533769bdc41cf0453bdd50d3b 209 PANTHER PTHR30086:SF14 1 209 2.3E-86 T 22-04-2016 TOLA_RS04020 a0c73a1a1349fec33a553fa6ca60ab4a 341 PANTHER PTHR38037 113 259 3.2E-38 T 22-04-2016 TOLA_RS04020 a0c73a1a1349fec33a553fa6ca60ab4a 341 Gene3D G3DSA:2.40.70.10 115 240 2.4E-40 T 22-04-2016 IPR021109 Aspartic peptidase domain TOLA_RS04020 a0c73a1a1349fec33a553fa6ca60ab4a 341 SUPERFAMILY SSF50630 117 246 8.81E-38 T 22-04-2016 IPR021109 Aspartic peptidase domain TOLA_RS04020 a0c73a1a1349fec33a553fa6ca60ab4a 341 Pfam PF05618 Putative ATP-dependant zinc protease 117 248 3.2E-35 T 22-04-2016 TOLA_RS13685 b4890583f72a57675ce7b9b1b7270bda 404 Gene3D G3DSA:3.40.640.10 55 279 3.3E-66 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS13685 b4890583f72a57675ce7b9b1b7270bda 404 Pfam PF00155 Aminotransferase class I and II 35 394 7.6E-48 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TOLA_RS13685 b4890583f72a57675ce7b9b1b7270bda 404 SUPERFAMILY SSF53383 6 402 5.17E-97 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS13685 b4890583f72a57675ce7b9b1b7270bda 404 PANTHER PTHR11751:SF303 9 400 9.8E-189 T 22-04-2016 TOLA_RS13685 b4890583f72a57675ce7b9b1b7270bda 404 PANTHER PTHR11751 9 400 9.8E-189 T 22-04-2016 TOLA_RS13685 b4890583f72a57675ce7b9b1b7270bda 404 Gene3D G3DSA:3.90.1150.10 280 403 5.2E-44 T 22-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TOLA_RS06550 b8f858a99a698418897537a6c22b2f52 323 SUPERFAMILY SSF51735 2 155 1.82E-17 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS06550 b8f858a99a698418897537a6c22b2f52 323 SUPERFAMILY SSF55347 119 248 9.37E-6 T 22-04-2016 TOLA_RS06550 b8f858a99a698418897537a6c22b2f52 323 PANTHER PTHR22604:SF123 4 173 1.3E-14 T 22-04-2016 TOLA_RS06550 b8f858a99a698418897537a6c22b2f52 323 Gene3D G3DSA:3.40.50.720 2 170 5.9E-19 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS06550 b8f858a99a698418897537a6c22b2f52 323 PANTHER PTHR22604 4 173 1.3E-14 T 22-04-2016 TOLA_RS06550 b8f858a99a698418897537a6c22b2f52 323 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 103 1.0E-7 T 22-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 TOLA_RS12715 4fac9ee081cad4f5c403bed8d8b0bd40 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 148 3.7E-26 T 22-04-2016 IPR020069 Ribosomal protein L9, C-terminal TOLA_RS12715 4fac9ee081cad4f5c403bed8d8b0bd40 149 SUPERFAMILY SSF55653 60 149 2.49E-26 T 22-04-2016 IPR020069 Ribosomal protein L9, C-terminal TOLA_RS12715 4fac9ee081cad4f5c403bed8d8b0bd40 149 PANTHER PTHR21368 1 149 5.9E-51 T 22-04-2016 IPR000244 Ribosomal protein L9 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12715 4fac9ee081cad4f5c403bed8d8b0bd40 149 SUPERFAMILY SSF55658 1 57 1.73E-17 T 22-04-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal TOLA_RS12715 4fac9ee081cad4f5c403bed8d8b0bd40 149 Gene3D G3DSA:3.10.430.100 61 149 9.9E-29 T 22-04-2016 IPR020069 Ribosomal protein L9, C-terminal TOLA_RS12715 4fac9ee081cad4f5c403bed8d8b0bd40 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 5.2E-52 T 22-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12715 4fac9ee081cad4f5c403bed8d8b0bd40 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 1.2E-19 T 22-04-2016 IPR020070 Ribosomal protein L9, N-terminal TOLA_RS12715 4fac9ee081cad4f5c403bed8d8b0bd40 149 Gene3D G3DSA:3.40.5.10 1 52 6.8E-23 T 22-04-2016 IPR020070 Ribosomal protein L9, N-terminal TOLA_RS12715 4fac9ee081cad4f5c403bed8d8b0bd40 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 25.019 T 22-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12715 4fac9ee081cad4f5c403bed8d8b0bd40 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 22-04-2016 IPR020070 Ribosomal protein L9, N-terminal TOLA_RS13695 afa061a22984eb8aaa19b279b111ab9f 184 PANTHER PTHR23026:SF107 5 167 2.5E-75 T 22-04-2016 TOLA_RS13695 afa061a22984eb8aaa19b279b111ab9f 184 Pfam PF00881 Nitroreductase family 11 163 4.1E-24 T 22-04-2016 IPR029479 Nitroreductase TOLA_RS13695 afa061a22984eb8aaa19b279b111ab9f 184 PANTHER PTHR23026 5 167 2.5E-75 T 22-04-2016 TOLA_RS13695 afa061a22984eb8aaa19b279b111ab9f 184 Gene3D G3DSA:3.40.109.10 3 183 2.5E-37 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 TOLA_RS13695 afa061a22984eb8aaa19b279b111ab9f 184 SUPERFAMILY SSF55469 6 183 1.05E-37 T 22-04-2016 IPR000415 Nitroreductase-like GO:0016491 TOLA_RS13695 afa061a22984eb8aaa19b279b111ab9f 184 PIRSF PIRSF000232 1 184 7.4E-62 T 22-04-2016 IPR026021 Putative NAD(P)H nitroreductase YdjA-like KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- TOLA_RS02360 8e083a0b7477b6721b6f914711af8be2 435 Pfam PF02378 Phosphotransferase system, EIIC 34 353 1.1E-54 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS02360 8e083a0b7477b6721b6f914711af8be2 435 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 18 425 4.1E-102 T 22-04-2016 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 TOLA_RS02360 8e083a0b7477b6721b6f914711af8be2 435 PIRSF PIRSF006351 6 433 6.8E-121 T 22-04-2016 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 TOLA_RS02360 8e083a0b7477b6721b6f914711af8be2 435 PANTHER PTHR33989 4 429 8.6E-128 T 22-04-2016 TOLA_RS06705 e5603f73abc56441df584c4a25ba6d37 275 PIRSF PIRSF012524 1 275 1.4E-71 T 22-04-2016 IPR014464 Conserved virulence factor B TOLA_RS06705 e5603f73abc56441df584c4a25ba6d37 275 Pfam PF13509 S1 domain 4 63 1.3E-15 T 22-04-2016 TOLA_RS06705 e5603f73abc56441df584c4a25ba6d37 275 Pfam PF13509 S1 domain 70 128 1.1E-8 T 22-04-2016 TOLA_RS06705 e5603f73abc56441df584c4a25ba6d37 275 PANTHER PTHR37296 1 274 1.4E-90 T 22-04-2016 TOLA_RS07505 e3a780b9a3d97edaeea70df9264074ed 698 SUPERFAMILY SSF52540 381 685 1.16E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07505 e3a780b9a3d97edaeea70df9264074ed 698 SUPERFAMILY SSF52540 199 329 1.16E-77 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07505 e3a780b9a3d97edaeea70df9264074ed 698 PANTHER PTHR11070:SF26 170 687 6.1E-119 T 22-04-2016 TOLA_RS07505 e3a780b9a3d97edaeea70df9264074ed 698 Pfam PF00580 UvrD/REP helicase N-terminal domain 202 484 6.4E-38 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TOLA_RS07505 e3a780b9a3d97edaeea70df9264074ed 698 Gene3D G3DSA:3.40.50.300 201 340 4.9E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07505 e3a780b9a3d97edaeea70df9264074ed 698 Gene3D G3DSA:3.40.50.300 391 489 4.9E-56 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07505 e3a780b9a3d97edaeea70df9264074ed 698 Pfam PF12462 DNA helicase IV / RNA helicase N terminal 5 166 2.2E-34 T 22-04-2016 IPR022161 DNA helicase IV, N-terminal domain TOLA_RS07505 e3a780b9a3d97edaeea70df9264074ed 698 PANTHER PTHR11070 170 687 6.1E-119 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS07505 e3a780b9a3d97edaeea70df9264074ed 698 Gene3D G3DSA:3.40.50.300 127 200 1.1E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07505 e3a780b9a3d97edaeea70df9264074ed 698 Gene3D G3DSA:3.40.50.300 596 685 1.1E-23 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07505 e3a780b9a3d97edaeea70df9264074ed 698 Pfam PF13361 UvrD-like helicase C-terminal domain 597 671 6.3E-15 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TOLA_RS15625 50d7eed304548a97fbef0de91d9f9079 335 Hamap MF_00070 2-keto-3-deoxygluconate permease [kdgT]. 1 318 36.477 T 22-04-2016 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 TOLA_RS15625 50d7eed304548a97fbef0de91d9f9079 335 Pfam PF03812 2-keto-3-deoxygluconate permease 3 312 1.2E-112 T 22-04-2016 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 TOLA_RS15625 50d7eed304548a97fbef0de91d9f9079 335 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 26 313 9.0E-100 T 22-04-2016 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 TOLA_RS15625 50d7eed304548a97fbef0de91d9f9079 335 TIGRFAM TIGR00793 kdgT: 2-keto-3-deoxygluconate transporter 1 313 4.6E-161 T 22-04-2016 IPR018395 2-keto-3-deoxygluconate permease, subgroup GO:0008643|GO:0015649|GO:0016021|GO:0046411 TOLA_RS06060 1cb11abbf2e790837faae2445319586b 238 PANTHER PTHR30399 1 238 1.4E-41 T 22-04-2016 TOLA_RS06060 1cb11abbf2e790837faae2445319586b 238 Pfam PF01863 Protein of unknown function DUF45 22 228 3.0E-60 T 22-04-2016 IPR002725 Protein of unknown function DUF45 TOLA_RS13225 1a68ad31e8884a0024dc1d911b4d19b3 256 PANTHER PTHR10060 1 256 2.2E-84 T 22-04-2016 IPR001130 TatD family GO:0016788 TOLA_RS13225 1a68ad31e8884a0024dc1d911b4d19b3 256 SUPERFAMILY SSF51556 2 254 1.09E-75 T 22-04-2016 IPR032466 Metal-dependent hydrolase TOLA_RS13225 1a68ad31e8884a0024dc1d911b4d19b3 256 Gene3D G3DSA:3.20.20.140 1 254 3.1E-78 T 22-04-2016 TOLA_RS13225 1a68ad31e8884a0024dc1d911b4d19b3 256 Pfam PF01026 TatD related DNase 3 252 7.0E-64 T 22-04-2016 IPR001130 TatD family GO:0016788 TOLA_RS13225 1a68ad31e8884a0024dc1d911b4d19b3 256 PIRSF PIRSF005902 1 256 3.2E-64 T 22-04-2016 IPR001130 TatD family GO:0016788 TOLA_RS13225 1a68ad31e8884a0024dc1d911b4d19b3 256 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 22-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 TOLA_RS04525 99c553e5b0ad9da73873c48ea7e144b6 276 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 162 172 - T 22-04-2016 IPR024002 Formate/nitrite transporter, conserved site TOLA_RS04525 99c553e5b0ad9da73873c48ea7e144b6 276 Pfam PF01226 Formate/nitrite transporter 18 270 8.8E-72 T 22-04-2016 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 TOLA_RS04525 99c553e5b0ad9da73873c48ea7e144b6 276 Gene3D G3DSA:1.20.1080.10 29 274 3.2E-83 T 22-04-2016 IPR023271 Aquaporin-like TOLA_RS04525 99c553e5b0ad9da73873c48ea7e144b6 276 TIGRFAM TIGR04060 formate_focA: formate transporter FocA 16 273 5.2E-115 T 22-04-2016 IPR023999 Formate transporter FocA, putative GO:0015499|GO:0015724|GO:0016021 TOLA_RS04525 99c553e5b0ad9da73873c48ea7e144b6 276 PANTHER PTHR30520 8 222 1.7E-99 T 22-04-2016 TOLA_RS04525 99c553e5b0ad9da73873c48ea7e144b6 276 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 26 272 5.9E-81 T 22-04-2016 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 TOLA_RS04525 99c553e5b0ad9da73873c48ea7e144b6 276 PANTHER PTHR30520 239 274 1.7E-99 T 22-04-2016 TOLA_RS04525 99c553e5b0ad9da73873c48ea7e144b6 276 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 77 86 - T 22-04-2016 IPR024002 Formate/nitrite transporter, conserved site TOLA_RS04525 99c553e5b0ad9da73873c48ea7e144b6 276 PANTHER PTHR30520:SF4 239 274 1.7E-99 T 22-04-2016 TOLA_RS04525 99c553e5b0ad9da73873c48ea7e144b6 276 PANTHER PTHR30520:SF4 8 222 1.7E-99 T 22-04-2016 TOLA_RS12455 68c60e0e21a58e10005f4e05b819888c 310 Pfam PF06834 TraU protein 31 298 3.7E-73 T 22-04-2016 IPR009649 TraU TOLA_RS12455 68c60e0e21a58e10005f4e05b819888c 310 TIGRFAM TIGR03756 conj_TIGR03756: integrating conjugative element protein, PFL_4710 family 24 308 4.2E-134 T 22-04-2016 IPR026331 Integrating conjugative element protein PFL_4710 TOLA_RS06920 9ef29c05a6bf5e6d2458600065a3181f 341 SUPERFAMILY SSF111369 46 242 2.48E-16 T 22-04-2016 TOLA_RS06920 9ef29c05a6bf5e6d2458600065a3181f 341 Pfam PF00529 HlyD membrane-fusion protein of T1SS 18 315 1.4E-7 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 TOLA_RS06920 9ef29c05a6bf5e6d2458600065a3181f 341 PANTHER PTHR30469 25 341 6.8E-50 T 22-04-2016 TOLA_RS06920 9ef29c05a6bf5e6d2458600065a3181f 341 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 42 245 1.1E-21 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TOLA_RS06920 9ef29c05a6bf5e6d2458600065a3181f 341 Gene3D G3DSA:2.40.50.100 63 88 7.9E-9 T 22-04-2016 TOLA_RS06920 9ef29c05a6bf5e6d2458600065a3181f 341 Gene3D G3DSA:2.40.50.100 149 180 7.9E-9 T 22-04-2016 TOLA_RS06920 9ef29c05a6bf5e6d2458600065a3181f 341 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 30 331 3.1E-56 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 TOLA_RS13495 7948f58bb50b0ad26223d28c6391226b 489 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 477 7.9E-127 T 22-04-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 TOLA_RS13495 7948f58bb50b0ad26223d28c6391226b 489 PANTHER PTHR22773:SF41 1 489 1.4E-159 T 22-04-2016 TOLA_RS13495 7948f58bb50b0ad26223d28c6391226b 489 PANTHER PTHR22773 1 489 1.4E-159 T 22-04-2016 TOLA_RS13495 7948f58bb50b0ad26223d28c6391226b 489 Pfam PF00361 Proton-conducting membrane transporter 122 422 5.5E-71 T 22-04-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 TOLA_RS13495 7948f58bb50b0ad26223d28c6391226b 489 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 478 17.39 T 22-04-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 TOLA_RS05375 0f8eb0d10e983f2624b6e633c6cffc27 383 Gene3D G3DSA:3.40.50.1970 2 184 3.0E-51 T 22-04-2016 TOLA_RS05375 0f8eb0d10e983f2624b6e633c6cffc27 383 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 260 280 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS05375 0f8eb0d10e983f2624b6e633c6cffc27 383 Gene3D G3DSA:1.20.1090.10 185 383 8.2E-71 T 22-04-2016 TOLA_RS05375 0f8eb0d10e983f2624b6e633c6cffc27 383 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 375 3.2E-114 T 22-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 TOLA_RS05375 0f8eb0d10e983f2624b6e633c6cffc27 383 PANTHER PTHR11496:SF74 1 382 1.2E-179 T 22-04-2016 TOLA_RS05375 0f8eb0d10e983f2624b6e633c6cffc27 383 SUPERFAMILY SSF56796 5 382 3.27E-118 T 22-04-2016 TOLA_RS05375 0f8eb0d10e983f2624b6e633c6cffc27 383 PANTHER PTHR11496 1 382 1.2E-179 T 22-04-2016 TOLA_RS05375 0f8eb0d10e983f2624b6e633c6cffc27 383 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 173 201 - T 22-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TOLA_RS14025 d544f435b65c275c30ba9f520607199c 265 TIGRFAM TIGR00444 mazG: MazG family protein 13 262 2.5E-106 T 22-04-2016 IPR011551 NTP pyrophosphohydrolase MazG TOLA_RS14025 d544f435b65c275c30ba9f520607199c 265 Gene3D G3DSA:1.10.287.1080 136 223 5.9E-13 T 22-04-2016 TOLA_RS14025 d544f435b65c275c30ba9f520607199c 265 Gene3D G3DSA:1.10.287.1080 12 75 6.0E-8 T 22-04-2016 TOLA_RS14025 d544f435b65c275c30ba9f520607199c 265 SUPERFAMILY SSF101386 140 242 1.44E-24 T 22-04-2016 TOLA_RS14025 d544f435b65c275c30ba9f520607199c 265 SUPERFAMILY SSF101386 5 106 1.96E-24 T 22-04-2016 TOLA_RS14025 d544f435b65c275c30ba9f520607199c 265 PANTHER PTHR30522 7 265 1.0E-121 T 22-04-2016 TOLA_RS14025 d544f435b65c275c30ba9f520607199c 265 PANTHER PTHR30522:SF0 7 265 1.0E-121 T 22-04-2016 IPR011551 NTP pyrophosphohydrolase MazG TOLA_RS14025 d544f435b65c275c30ba9f520607199c 265 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 103 2.9E-27 T 22-04-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TOLA_RS14025 d544f435b65c275c30ba9f520607199c 265 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 171 231 3.7E-8 T 22-04-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TOLA_RS14450 fa942b76653aea16c5d3cef8837f31b0 449 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 298 317 4.7E-14 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TOLA_RS14450 fa942b76653aea16c5d3cef8837f31b0 449 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 384 404 4.7E-14 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TOLA_RS14450 fa942b76653aea16c5d3cef8837f31b0 449 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 427 447 4.7E-14 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TOLA_RS14450 fa942b76653aea16c5d3cef8837f31b0 449 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 4.7E-14 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TOLA_RS14450 fa942b76653aea16c5d3cef8837f31b0 449 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 4.7E-14 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TOLA_RS14450 fa942b76653aea16c5d3cef8837f31b0 449 PANTHER PTHR11616 4 446 6.0E-133 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TOLA_RS14450 fa942b76653aea16c5d3cef8837f31b0 449 Pfam PF00209 Sodium:neurotransmitter symporter family 5 122 7.8E-22 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TOLA_RS14450 fa942b76653aea16c5d3cef8837f31b0 449 Pfam PF00209 Sodium:neurotransmitter symporter family 151 446 2.6E-30 T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TOLA_RS14450 fa942b76653aea16c5d3cef8837f31b0 449 PANTHER PTHR11616:SF167 4 446 6.0E-133 T 22-04-2016 TOLA_RS14450 fa942b76653aea16c5d3cef8837f31b0 449 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 22-04-2016 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TOLA_RS14450 fa942b76653aea16c5d3cef8837f31b0 449 SUPERFAMILY SSF161070 4 446 1.57E-128 T 22-04-2016 TOLA_RS00705 dee52a0eb6fe69f43aa2c1f7681e06ae 418 PANTHER PTHR23417 128 138 7.4E-115 T 22-04-2016 TOLA_RS00705 dee52a0eb6fe69f43aa2c1f7681e06ae 418 PANTHER PTHR23417 1 109 7.4E-115 T 22-04-2016 TOLA_RS00705 dee52a0eb6fe69f43aa2c1f7681e06ae 418 PANTHER PTHR23417 188 417 7.4E-115 T 22-04-2016 TOLA_RS00705 dee52a0eb6fe69f43aa2c1f7681e06ae 418 SUPERFAMILY SSF53756 56 400 4.71E-18 T 22-04-2016 TOLA_RS00705 dee52a0eb6fe69f43aa2c1f7681e06ae 418 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 33 209 3.1E-65 T 22-04-2016 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675|UniPathway: UPA00958 TOLA_RS00705 dee52a0eb6fe69f43aa2c1f7681e06ae 418 PANTHER PTHR23417:SF2 128 138 7.4E-115 T 22-04-2016 TOLA_RS00705 dee52a0eb6fe69f43aa2c1f7681e06ae 418 PANTHER PTHR23417:SF2 1 109 7.4E-115 T 22-04-2016 TOLA_RS00705 dee52a0eb6fe69f43aa2c1f7681e06ae 418 PANTHER PTHR23417:SF2 188 417 7.4E-115 T 22-04-2016 TOLA_RS00705 dee52a0eb6fe69f43aa2c1f7681e06ae 418 Pfam PF00534 Glycosyl transferases group 1 233 392 2.8E-6 T 22-04-2016 IPR001296 Glycosyl transferase, family 1 TOLA_RS01255 8af3927182040e5c42a5078f78348ce2 315 Gene3D G3DSA:3.40.190.10 180 260 7.0E-12 T 22-04-2016 TOLA_RS01255 8af3927182040e5c42a5078f78348ce2 315 Gene3D G3DSA:1.10.10.10 2 79 3.5E-22 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS01255 8af3927182040e5c42a5078f78348ce2 315 PANTHER PTHR30126 1 309 1.1E-120 T 22-04-2016 TOLA_RS01255 8af3927182040e5c42a5078f78348ce2 315 Gene3D G3DSA:3.40.190.10 89 179 4.3E-18 T 22-04-2016 TOLA_RS01255 8af3927182040e5c42a5078f78348ce2 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.5E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS01255 8af3927182040e5c42a5078f78348ce2 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.5E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS01255 8af3927182040e5c42a5078f78348ce2 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.5E-5 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS01255 8af3927182040e5c42a5078f78348ce2 315 SUPERFAMILY SSF53850 87 289 2.17E-33 T 22-04-2016 TOLA_RS01255 8af3927182040e5c42a5078f78348ce2 315 Pfam PF03466 LysR substrate binding domain 86 273 1.3E-33 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS01255 8af3927182040e5c42a5078f78348ce2 315 PANTHER PTHR30126:SF10 1 309 1.1E-120 T 22-04-2016 TOLA_RS01255 8af3927182040e5c42a5078f78348ce2 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.8E-17 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS01255 8af3927182040e5c42a5078f78348ce2 315 SUPERFAMILY SSF46785 2 86 3.08E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS13420 2dfb59028dacb464ab16f3307e3f4697 333 Pfam PF02653 Branched-chain amino acid transport system / permease component 39 322 3.5E-48 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS13420 2dfb59028dacb464ab16f3307e3f4697 333 PANTHER PTHR32196 1 333 1.6E-215 T 22-04-2016 TOLA_RS13420 2dfb59028dacb464ab16f3307e3f4697 333 PANTHER PTHR32196:SF18 1 333 1.6E-215 T 22-04-2016 IPR030158 Galactoside transport system permease protein MglC GO:0008643|GO:0016021 TOLA_RS10300 6b8e2367f8ced7c5fc892cb6b1f3cb1a 124 SMART SM00450 22 119 2.2E-17 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS10300 6b8e2367f8ced7c5fc892cb6b1f3cb1a 124 Pfam PF00581 Rhodanese-like domain 24 115 7.4E-16 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS10300 6b8e2367f8ced7c5fc892cb6b1f3cb1a 124 PANTHER PTHR12231 30 122 2.9E-14 T 22-04-2016 TOLA_RS10300 6b8e2367f8ced7c5fc892cb6b1f3cb1a 124 Gene3D G3DSA:3.40.250.10 8 122 2.0E-31 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS10300 6b8e2367f8ced7c5fc892cb6b1f3cb1a 124 SUPERFAMILY SSF52821 4 122 1.7E-34 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS02315 89547e4abdebe7750ad449f70a07e31c 99 Gene3D G3DSA:3.40.50.2300 1 97 2.4E-40 T 22-04-2016 TOLA_RS02315 89547e4abdebe7750ad449f70a07e31c 99 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 95 1.2E-18 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS02315 89547e4abdebe7750ad449f70a07e31c 99 SUPERFAMILY SSF52794 2 98 2.96E-35 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS02315 89547e4abdebe7750ad449f70a07e31c 99 PANTHER PTHR30505:SF0 1 96 2.0E-39 T 22-04-2016 TOLA_RS02315 89547e4abdebe7750ad449f70a07e31c 99 PANTHER PTHR30505 1 96 2.0E-39 T 22-04-2016 TOLA_RS02315 89547e4abdebe7750ad449f70a07e31c 99 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 88 4.9E-34 T 22-04-2016 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 TOLA_RS03055 ddf44cc802ab4cb820398877984ed7a7 376 PANTHER PTHR30294:SF22 1 371 2.7E-181 T 22-04-2016 TOLA_RS03055 ddf44cc802ab4cb820398877984ed7a7 376 Pfam PF12698 ABC-2 family transporter protein 25 364 2.8E-34 T 22-04-2016 TOLA_RS03055 ddf44cc802ab4cb820398877984ed7a7 376 PANTHER PTHR30294 1 371 2.7E-181 T 22-04-2016 TOLA_RS06700 f509c12ff643d7bb47c85b7a133e7884 266 Pfam PF10899 Putative abortive phage resistance protein AbiGi, antitoxin 83 167 1.4E-5 T 22-04-2016 IPR021223 Abortive phage resistance protein AbiGi TOLA_RS13000 cc9a6b1738a63c90772d5e7b2dfd142b 321 PIRSF PIRSF006268 2 316 5.2E-90 T 22-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 TOLA_RS13000 cc9a6b1738a63c90772d5e7b2dfd142b 321 Pfam PF02424 ApbE family 15 294 1.0E-76 T 22-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 TOLA_RS13000 cc9a6b1738a63c90772d5e7b2dfd142b 321 SUPERFAMILY SSF143631 7 307 1.28E-88 T 22-04-2016 IPR003374 ApbE-like domain TOLA_RS13000 cc9a6b1738a63c90772d5e7b2dfd142b 321 PANTHER PTHR30040 5 318 9.5E-92 T 22-04-2016 TOLA_RS13000 cc9a6b1738a63c90772d5e7b2dfd142b 321 PANTHER PTHR30040:SF2 5 318 9.5E-92 T 22-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 TOLA_RS03935 284608a3f4615dbfba5499b999540fef 281 SUPERFAMILY SSF56219 54 276 3.01E-20 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase TOLA_RS03935 284608a3f4615dbfba5499b999540fef 281 Gene3D G3DSA:3.60.10.10 54 206 3.2E-6 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase TOLA_RS03935 284608a3f4615dbfba5499b999540fef 281 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 61 266 4.1E-7 T 22-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase TOLA_RS07660 fefe626f38efaae11a9eccfa1b9ccb1f 211 Pfam PF02627 Carboxymuconolactone decarboxylase family 7 66 1.7E-6 T 22-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS07660 fefe626f38efaae11a9eccfa1b9ccb1f 211 Pfam PF02627 Carboxymuconolactone decarboxylase family 123 206 8.6E-10 T 22-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS07660 fefe626f38efaae11a9eccfa1b9ccb1f 211 PANTHER PTHR33570 1 208 1.4E-14 T 22-04-2016 TOLA_RS07660 fefe626f38efaae11a9eccfa1b9ccb1f 211 Gene3D G3DSA:1.20.1290.10 6 78 3.5E-11 T 22-04-2016 IPR029032 AhpD-like TOLA_RS07660 fefe626f38efaae11a9eccfa1b9ccb1f 211 Gene3D G3DSA:1.20.1290.10 122 208 3.8E-10 T 22-04-2016 IPR029032 AhpD-like TOLA_RS07660 fefe626f38efaae11a9eccfa1b9ccb1f 211 SUPERFAMILY SSF69118 6 209 4.97E-43 T 22-04-2016 IPR029032 AhpD-like TOLA_RS05160 ba4d7b67b1c54fbfa393d27fad7f18e2 483 Pfam PF03773 Predicted permease 17 446 4.5E-69 T 22-04-2016 IPR005524 Predicted permease DUF318 TOLA_RS05160 ba4d7b67b1c54fbfa393d27fad7f18e2 483 PANTHER PTHR34184 17 188 1.1E-93 T 22-04-2016 TOLA_RS05160 ba4d7b67b1c54fbfa393d27fad7f18e2 483 PANTHER PTHR34184 293 465 1.1E-93 T 22-04-2016 TOLA_RS05160 ba4d7b67b1c54fbfa393d27fad7f18e2 483 PANTHER PTHR34184:SF3 17 188 1.1E-93 T 22-04-2016 TOLA_RS05160 ba4d7b67b1c54fbfa393d27fad7f18e2 483 PANTHER PTHR34184:SF3 293 465 1.1E-93 T 22-04-2016 TOLA_RS01975 8e312e4c5b556b50eb0a8978234fed72 143 Pfam PF00011 Hsp20/alpha crystallin family 43 143 1.6E-24 T 22-04-2016 IPR002068 Alpha crystallin/Hsp20 domain TOLA_RS01975 8e312e4c5b556b50eb0a8978234fed72 143 SUPERFAMILY SSF49764 7 142 1.07E-35 T 22-04-2016 IPR008978 HSP20-like chaperone TOLA_RS01975 8e312e4c5b556b50eb0a8978234fed72 143 PANTHER PTHR11527:SF118 6 142 1.0E-30 T 22-04-2016 TOLA_RS01975 8e312e4c5b556b50eb0a8978234fed72 143 PANTHER PTHR11527 6 142 1.0E-30 T 22-04-2016 IPR031107 Small heat shock protein HSP20 TOLA_RS01975 8e312e4c5b556b50eb0a8978234fed72 143 Gene3D G3DSA:2.60.40.790 2 142 6.5E-39 T 22-04-2016 IPR008978 HSP20-like chaperone TOLA_RS03705 4d1a61362c513a071f5d119bd0c0caae 91 SUPERFAMILY SSF47729 1 90 6.33E-25 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 TOLA_RS03705 4d1a61362c513a071f5d119bd0c0caae 91 Gene3D G3DSA:4.10.520.10 1 91 1.1E-26 T 22-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 TOLA_RS03705 4d1a61362c513a071f5d119bd0c0caae 91 SMART SM00411 1 90 4.1E-23 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS03705 4d1a61362c513a071f5d119bd0c0caae 91 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.1E-25 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS03705 4d1a61362c513a071f5d119bd0c0caae 91 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 3.6E-11 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS03705 4d1a61362c513a071f5d119bd0c0caae 91 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 3.6E-11 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS03705 4d1a61362c513a071f5d119bd0c0caae 91 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 3.6E-11 T 22-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TOLA_RS03705 4d1a61362c513a071f5d119bd0c0caae 91 PANTHER PTHR33175 1 90 3.1E-25 T 22-04-2016 TOLA_RS00475 ac82ab4fcabe22bc5fe22dd1c492ed42 180 SUPERFAMILY SSF56925 46 173 6.8E-5 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 TOLA_RS00475 ac82ab4fcabe22bc5fe22dd1c492ed42 180 Gene3D G3DSA:2.40.160.20 31 180 2.1E-43 T 22-04-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 TOLA_RS00475 ac82ab4fcabe22bc5fe22dd1c492ed42 180 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 46 177 1.1E-21 T 22-04-2016 IPR018550 Lipid A 3-O-deacylase-related TOLA_RS00475 ac82ab4fcabe22bc5fe22dd1c492ed42 180 PIRSF PIRSF029681 2 180 1.1E-39 T 22-04-2016 IPR018550 Lipid A 3-O-deacylase-related TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 7 15 - T 22-04-2016 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 Gene3D G3DSA:3.40.50.1170 3 194 1.5E-79 T 22-04-2016 IPR027474 L-asparaginase, N-terminal TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 Pfam PF00710 Asparaginase, N-terminal 4 189 4.2E-67 T 22-04-2016 IPR027474 L-asparaginase, N-terminal TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 PIRSF PIRSF001220 1 333 4.8E-95 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 Gene3D G3DSA:3.40.50.40 210 334 1.1E-48 T 22-04-2016 IPR027473 L-asparaginase, C-terminal domain TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 SMART SM00870 4 322 2.4E-141 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 SUPERFAMILY SSF53774 1 334 8.9E-113 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 PANTHER PTHR11707 1 334 2.3E-220 T 22-04-2016 TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 PIRSF PIRSF500176 1 331 1.3E-110 T 22-04-2016 TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 2 334 7.3E-115 T 22-04-2016 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 PANTHER PTHR11707:SF31 1 334 2.3E-220 T 22-04-2016 TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 83 93 - T 22-04-2016 IPR027475 Asparaginase/glutaminase, active site 2 TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 PRINTS PR00139 Asparaginase/glutaminase family signature 5 16 9.1E-16 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 PRINTS PR00139 Asparaginase/glutaminase family signature 259 277 9.1E-16 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 TOLA_RS13705 b88ca524a8163b1937978db325ed674a 335 PRINTS PR00139 Asparaginase/glutaminase family signature 82 100 9.1E-16 T 22-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 TOLA_RS00650 d236935d604bb62be33264fe37b46841 128 SUPERFAMILY SSF64263 1 119 1.57E-51 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00650 d236935d604bb62be33264fe37b46841 128 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 116 7.9E-49 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00650 d236935d604bb62be33264fe37b46841 128 Gene3D G3DSA:3.90.1030.10 1 116 3.2E-51 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00650 d236935d604bb62be33264fe37b46841 128 Pfam PF01196 Ribosomal protein L17 20 116 5.1E-35 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00650 d236935d604bb62be33264fe37b46841 128 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00650 d236935d604bb62be33264fe37b46841 128 PANTHER PTHR14413 1 121 1.6E-70 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00650 d236935d604bb62be33264fe37b46841 128 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 27.04 T 22-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS16060 68d410a5e551e25c10052910d3e64247 389 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 2 387 1.6E-95 T 22-04-2016 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 UniPathway: UPA00252 TOLA_RS16060 68d410a5e551e25c10052910d3e64247 389 Gene3D G3DSA:1.25.40.10 274 387 7.2E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS16060 68d410a5e551e25c10052910d3e64247 389 Gene3D G3DSA:1.25.40.10 88 209 5.5E-7 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS16060 68d410a5e551e25c10052910d3e64247 389 Pfam PF07219 HemY protein N-terminus 26 132 2.2E-31 T 22-04-2016 IPR010817 HemY, N-terminal UniPathway: UPA00252 TOLA_RS16060 68d410a5e551e25c10052910d3e64247 389 SUPERFAMILY SSF48452 86 226 1.67E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS16060 68d410a5e551e25c10052910d3e64247 389 SUPERFAMILY SSF48452 310 360 1.67E-9 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS12095 fb0b86e87b8d9237a1304d66dc72ce19 103 PANTHER PTHR21349 1 101 5.6E-44 T 22-04-2016 TOLA_RS12095 fb0b86e87b8d9237a1304d66dc72ce19 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 4.6E-44 T 22-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12095 fb0b86e87b8d9237a1304d66dc72ce19 103 SUPERFAMILY SSF141091 1 102 8.89E-38 T 22-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 TOLA_RS12095 fb0b86e87b8d9237a1304d66dc72ce19 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 2.4E-39 T 22-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 TOLA_RS12095 fb0b86e87b8d9237a1304d66dc72ce19 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 22-04-2016 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12095 fb0b86e87b8d9237a1304d66dc72ce19 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.361 T 22-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS07515 550b6f74e8429dba81116a32d47ecac6 167 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 1 165 3.5E-66 T 22-04-2016 IPR020761 Uncharacterised protein family UPF0114, bacteria TOLA_RS07515 550b6f74e8429dba81116a32d47ecac6 167 PANTHER PTHR38596:SF1 1 162 4.5E-89 T 22-04-2016 TOLA_RS07515 550b6f74e8429dba81116a32d47ecac6 167 Pfam PF03350 Uncharacterized protein family, UPF0114 9 125 5.7E-34 T 22-04-2016 IPR005134 Uncharacterised protein family UPF0114 TOLA_RS07515 550b6f74e8429dba81116a32d47ecac6 167 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 167 87.087 T 22-04-2016 IPR020765 Uncharacterised protein family UPF0114, gammaproteobacteria GO:0005886 TOLA_RS07515 550b6f74e8429dba81116a32d47ecac6 167 PANTHER PTHR38596 1 162 4.5E-89 T 22-04-2016 TOLA_RS01130 511a44bbffe6ada2911ab0dcaa5caac9 225 Pfam PF00043 Glutathione S-transferase, C-terminal domain 130 192 4.0E-11 T 22-04-2016 IPR004046 Glutathione S-transferase, C-terminal TOLA_RS01130 511a44bbffe6ada2911ab0dcaa5caac9 225 PANTHER PTHR11260:SF178 4 198 3.0E-59 T 22-04-2016 TOLA_RS01130 511a44bbffe6ada2911ab0dcaa5caac9 225 Gene3D G3DSA:3.40.30.10 1 78 1.1E-26 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS01130 511a44bbffe6ada2911ab0dcaa5caac9 225 Gene3D G3DSA:1.20.1050.10 79 196 9.8E-45 T 22-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like TOLA_RS01130 511a44bbffe6ada2911ab0dcaa5caac9 225 SUPERFAMILY SSF52833 1 80 6.28E-23 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS01130 511a44bbffe6ada2911ab0dcaa5caac9 225 PANTHER PTHR11260 4 198 3.0E-59 T 22-04-2016 TOLA_RS01130 511a44bbffe6ada2911ab0dcaa5caac9 225 SUPERFAMILY SSF47616 73 200 1.2E-33 T 22-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like TOLA_RS01130 511a44bbffe6ada2911ab0dcaa5caac9 225 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 76 1.0E-13 T 22-04-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 TOLA_RS09470 85ebc595ad786a90f2682a7451d9dc40 503 Gene3D G3DSA:2.40.10.10 253 298 1.2E-4 T 22-04-2016 TOLA_RS09470 85ebc595ad786a90f2682a7451d9dc40 503 SUPERFAMILY SSF50494 233 301 3.69E-9 T 22-04-2016 IPR009003 Peptidase S1, PA clan TOLA_RS09470 85ebc595ad786a90f2682a7451d9dc40 503 SUPERFAMILY SSF50494 333 463 3.69E-9 T 22-04-2016 IPR009003 Peptidase S1, PA clan TOLA_RS09470 85ebc595ad786a90f2682a7451d9dc40 503 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 272 277 - T 22-04-2016 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 TOLA_RS08145 22eee32f2d530873f1200fbcf6204b7f 285 Gene3D G3DSA:1.10.3210.10 140 189 9.8E-10 T 22-04-2016 IPR006674 HD domain TOLA_RS08145 22eee32f2d530873f1200fbcf6204b7f 285 SUPERFAMILY SSF109604 132 191 3.14E-11 T 22-04-2016 TOLA_RS08145 22eee32f2d530873f1200fbcf6204b7f 285 TIGRFAM TIGR00277 HDIG: HDIG domain 140 187 4.0E-9 T 22-04-2016 IPR006675 HDIG domain TOLA_RS08145 22eee32f2d530873f1200fbcf6204b7f 285 Pfam PF01966 HD domain 144 189 1.5E-7 T 22-04-2016 IPR006674 HD domain TOLA_RS00810 8832db0f4fa5ddcd6b7ed978c5e279a9 190 PANTHER PTHR11390 1 188 3.9E-75 T 22-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TOLA_RS00810 8832db0f4fa5ddcd6b7ed978c5e279a9 190 SUPERFAMILY SSF57783 66 102 4.59E-11 T 22-04-2016 TOLA_RS00810 8832db0f4fa5ddcd6b7ed978c5e279a9 190 SUPERFAMILY SSF57783 18 59 3.57E-11 T 22-04-2016 TOLA_RS00810 8832db0f4fa5ddcd6b7ed978c5e279a9 190 Gene3D G3DSA:3.30.65.10 23 59 1.8E-11 T 22-04-2016 TOLA_RS00810 8832db0f4fa5ddcd6b7ed978c5e279a9 190 Gene3D G3DSA:3.30.65.10 115 147 6.3E-7 T 22-04-2016 TOLA_RS00810 8832db0f4fa5ddcd6b7ed978c5e279a9 190 Gene3D G3DSA:3.30.65.10 66 100 1.6E-12 T 22-04-2016 TOLA_RS00810 8832db0f4fa5ddcd6b7ed978c5e279a9 190 PANTHER PTHR11390:SF26 1 188 3.9E-75 T 22-04-2016 TOLA_RS00810 8832db0f4fa5ddcd6b7ed978c5e279a9 190 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 70 101 6.3E-14 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 TOLA_RS00810 8832db0f4fa5ddcd6b7ed978c5e279a9 190 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 21 57 1.1E-15 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 TOLA_RS00810 8832db0f4fa5ddcd6b7ed978c5e279a9 190 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 156 177 5.2E-4 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 TOLA_RS00810 8832db0f4fa5ddcd6b7ed978c5e279a9 190 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 115 152 8.9E-14 T 22-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 TOLA_RS06940 7d9641f8155d40ac491c44aace8f3f52 1102 SUPERFAMILY SSF52540 715 802 1.82E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06940 7d9641f8155d40ac491c44aace8f3f52 1102 SUPERFAMILY SSF52540 430 477 1.82E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06940 7d9641f8155d40ac491c44aace8f3f52 1102 SUPERFAMILY SSF52540 534 631 1.82E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06940 7d9641f8155d40ac491c44aace8f3f52 1102 SUPERFAMILY SSF52540 832 885 1.82E-15 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06940 7d9641f8155d40ac491c44aace8f3f52 1102 TIGRFAM TIGR02562 cas3_yersinia: CRISPR-associated helicase Cas3, subtype I-F/YPEST 1 1098 0.0 T 22-04-2016 IPR013395 Helicase Cas3, CRISPR-associated, Yersinia-type TOLA_RS06940 7d9641f8155d40ac491c44aace8f3f52 1102 Gene3D G3DSA:3.40.50.300 394 509 4.7E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS06940 7d9641f8155d40ac491c44aace8f3f52 1102 Gene3D G3DSA:3.40.50.300 556 632 4.7E-4 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 381 488 1.2E-16 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 Pfam PF00672 HAMP domain 214 279 6.5E-10 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 434 1.8E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 469 1.8E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 488 1.8E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 448 1.8E-11 T 22-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 PANTHER PTHR24423 228 488 7.8E-41 T 22-04-2016 TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 SMART SM00388 283 341 0.0017 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 SUPERFAMILY SSF47384 267 329 3.73E-9 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 Gene3D G3DSA:3.30.565.10 344 489 6.5E-29 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 SMART SM00387 380 490 1.7E-23 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 SUPERFAMILY SSF55874 345 489 6.68E-31 T 22-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 SMART SM00304 230 282 9.2E-6 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 PANTHER PTHR24423:SF533 228 488 7.8E-41 T 22-04-2016 TOLA_RS00100 26d635f9c6f612c517ba47809e1e6c0d 490 Gene3D G3DSA:1.10.287.130 273 333 1.2E-10 T 22-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TOLA_RS13945 b27b8077f3e1f10410398e426f21c8dd 64 Pfam PF02599 Global regulator protein family 1 52 1.5E-26 T 22-04-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 TOLA_RS13945 b27b8077f3e1f10410398e426f21c8dd 64 Hamap MF_00167 Carbon storage regulator [csrA]. 1 62 21.087 T 22-04-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 TOLA_RS13945 b27b8077f3e1f10410398e426f21c8dd 64 PANTHER PTHR34984:SF1 1 56 8.1E-32 T 22-04-2016 TOLA_RS13945 b27b8077f3e1f10410398e426f21c8dd 64 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 3.0E-20 T 22-04-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 TOLA_RS13945 b27b8077f3e1f10410398e426f21c8dd 64 SUPERFAMILY SSF117130 1 54 4.58E-21 T 22-04-2016 TOLA_RS13945 b27b8077f3e1f10410398e426f21c8dd 64 PANTHER PTHR34984 1 56 8.1E-32 T 22-04-2016 TOLA_RS13945 b27b8077f3e1f10410398e426f21c8dd 64 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 57 5.3E-30 T 22-04-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 TOLA_RS11860 627b04599ed51175c6f4ab30d27d0194 326 PANTHER PTHR30578 1 326 1.1E-103 T 22-04-2016 TOLA_RS11860 627b04599ed51175c6f4ab30d27d0194 326 Pfam PF03116 NQR2, RnfD, RnfE family 5 318 1.9E-102 T 22-04-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 TOLA_RS11860 627b04599ed51175c6f4ab30d27d0194 326 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 1 320 24.786 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 TOLA_RS11860 627b04599ed51175c6f4ab30d27d0194 326 PANTHER PTHR30578:SF0 1 326 1.1E-103 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 TOLA_RS11860 627b04599ed51175c6f4ab30d27d0194 326 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 6 318 2.4E-107 T 22-04-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 TOLA_RS15635 fd3652f1256e9477b38c0254b52d1a88 269 SUPERFAMILY SSF55781 80 260 7.36E-53 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS15635 fd3652f1256e9477b38c0254b52d1a88 269 Gene3D G3DSA:3.30.450.40 89 262 5.7E-66 T 22-04-2016 IPR029016 GAF domain-like TOLA_RS15635 fd3652f1256e9477b38c0254b52d1a88 269 PANTHER PTHR30136 1 269 2.6E-108 T 22-04-2016 TOLA_RS15635 fd3652f1256e9477b38c0254b52d1a88 269 SMART SM00346 16 105 7.9E-33 T 22-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TOLA_RS15635 fd3652f1256e9477b38c0254b52d1a88 269 SUPERFAMILY SSF46785 16 88 1.33E-15 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS15635 fd3652f1256e9477b38c0254b52d1a88 269 PANTHER PTHR30136:SF7 1 269 2.6E-108 T 22-04-2016 TOLA_RS15635 fd3652f1256e9477b38c0254b52d1a88 269 Pfam PF09339 IclR helix-turn-helix domain 18 68 2.9E-13 T 22-04-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TOLA_RS15635 fd3652f1256e9477b38c0254b52d1a88 269 Pfam PF01614 Bacterial transcriptional regulator 132 257 1.9E-42 T 22-04-2016 IPR014757 Transcription regulator IclR, C-terminal TOLA_RS15635 fd3652f1256e9477b38c0254b52d1a88 269 Gene3D G3DSA:1.10.10.10 14 88 8.9E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS07290 7a9cbd6cb27d1cd426188ea9c6d7fdf3 377 Gene3D G3DSA:1.10.620.20 3 341 1.1E-123 T 22-04-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 TOLA_RS07290 7a9cbd6cb27d1cd426188ea9c6d7fdf3 377 PANTHER PTHR23409 197 377 8.4E-258 T 22-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 TOLA_RS07290 7a9cbd6cb27d1cd426188ea9c6d7fdf3 377 PANTHER PTHR23409 1 173 8.4E-258 T 22-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 TOLA_RS07290 7a9cbd6cb27d1cd426188ea9c6d7fdf3 377 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 115 131 - T 22-04-2016 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 TOLA_RS07290 7a9cbd6cb27d1cd426188ea9c6d7fdf3 377 SUPERFAMILY SSF47240 3 342 2.23E-112 T 22-04-2016 IPR009078 Ferritin-like superfamily TOLA_RS07290 7a9cbd6cb27d1cd426188ea9c6d7fdf3 377 PANTHER PTHR23409:SF23 197 377 8.4E-258 T 22-04-2016 TOLA_RS07290 7a9cbd6cb27d1cd426188ea9c6d7fdf3 377 PANTHER PTHR23409:SF23 1 173 8.4E-258 T 22-04-2016 TOLA_RS07290 7a9cbd6cb27d1cd426188ea9c6d7fdf3 377 Pfam PF00268 Ribonucleotide reductase, small chain 32 333 2.3E-46 T 22-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 TOLA_RS00585 31a1b18aaee1bb8b2bccc451fd530555 101 PANTHER PTHR19836 1 101 4.5E-61 T 22-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00585 31a1b18aaee1bb8b2bccc451fd530555 101 SUPERFAMILY SSF57716 2 101 4.13E-38 T 22-04-2016 TOLA_RS00585 31a1b18aaee1bb8b2bccc451fd530555 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 9.6E-28 T 22-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00585 31a1b18aaee1bb8b2bccc451fd530555 101 ProSitePatterns PS00527 Ribosomal protein S14 signature. 63 85 - T 22-04-2016 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 TOLA_RS00585 31a1b18aaee1bb8b2bccc451fd530555 101 Gene3D G3DSA:4.10.830.10 41 101 2.4E-32 T 22-04-2016 TOLA_RS00585 31a1b18aaee1bb8b2bccc451fd530555 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.203 T 22-04-2016 IPR023036 Ribosomal protein S14, bacterial/plastid TOLA_RS08650 e001430e0107fd16689732cedfdce9ac 116 SUPERFAMILY SSF143414 44 107 9.55E-14 T 22-04-2016 TOLA_RS08650 e001430e0107fd16689732cedfdce9ac 116 PANTHER PTHR40449:SF2 1 116 2.8E-73 T 22-04-2016 TOLA_RS08650 e001430e0107fd16689732cedfdce9ac 116 PIRSF PIRSF012296 1 116 1.1E-57 T 22-04-2016 IPR009307 Ethanolamine utilisation EutS GO:0006580 TOLA_RS08650 e001430e0107fd16689732cedfdce9ac 116 Pfam PF00936 BMC domain 45 103 6.0E-12 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08650 e001430e0107fd16689732cedfdce9ac 116 SMART SM00877 44 116 6.6E-17 T 22-04-2016 IPR000249 Microcompartment protein, bacteria TOLA_RS08650 e001430e0107fd16689732cedfdce9ac 116 PANTHER PTHR40449 1 116 2.8E-73 T 22-04-2016 TOLA_RS09985 fd9fd51d6a1df41d779c07aa8f2c8e25 287 PANTHER PTHR30193:SF10 9 286 3.0E-77 T 22-04-2016 TOLA_RS09985 fd9fd51d6a1df41d779c07aa8f2c8e25 287 Gene3D G3DSA:1.10.3720.10 16 281 3.4E-42 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09985 fd9fd51d6a1df41d779c07aa8f2c8e25 287 SUPERFAMILY SSF161098 20 276 2.22E-46 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09985 fd9fd51d6a1df41d779c07aa8f2c8e25 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 278 1.4E-9 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09985 fd9fd51d6a1df41d779c07aa8f2c8e25 287 PANTHER PTHR30193 9 286 3.0E-77 T 22-04-2016 TOLA_RS16050 e51ad6caf0085e545e6bc7a8c4881811 241 SUPERFAMILY SSF69618 2 240 2.35E-47 T 22-04-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS16050 e51ad6caf0085e545e6bc7a8c4881811 241 Gene3D G3DSA:3.40.50.10090 4 112 2.4E-12 T 22-04-2016 TOLA_RS16050 e51ad6caf0085e545e6bc7a8c4881811 241 Gene3D G3DSA:3.40.50.10090 118 239 2.4E-10 T 22-04-2016 TOLA_RS16050 e51ad6caf0085e545e6bc7a8c4881811 241 PANTHER PTHR38042:SF1 1 239 4.7E-54 T 22-04-2016 TOLA_RS16050 e51ad6caf0085e545e6bc7a8c4881811 241 PANTHER PTHR38042 1 239 4.7E-54 T 22-04-2016 TOLA_RS16050 e51ad6caf0085e545e6bc7a8c4881811 241 Pfam PF02602 Uroporphyrinogen-III synthase HemD 14 226 5.3E-38 T 22-04-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 TOLA_RS12690 c75c8abed878f5516cded416dfa4425a 134 SUPERFAMILY SSF81343 6 132 8.67E-42 T 22-04-2016 TOLA_RS12690 c75c8abed878f5516cded416dfa4425a 134 Gene3D G3DSA:1.20.1300.10 6 132 4.8E-48 T 22-04-2016 TOLA_RS12690 c75c8abed878f5516cded416dfa4425a 134 PIRSF PIRSF000180 5 133 6.4E-39 T 22-04-2016 IPR003510 Fumarate reductase, subunit C GO:0016020 TOLA_RS12690 c75c8abed878f5516cded416dfa4425a 134 ProDom PD015900 FUMARATE MEMBRANE REDUCTASE C SUBUNIT TRANSMEMBRANE INNER HYDROPHOBIC REDUCTASE POLYPEPTIDE 11 113 2.0E-20 T 22-04-2016 IPR003510 Fumarate reductase, subunit C GO:0016020 TOLA_RS12690 c75c8abed878f5516cded416dfa4425a 134 Pfam PF02300 Fumarate reductase subunit C 6 131 1.8E-49 T 22-04-2016 IPR003510 Fumarate reductase, subunit C GO:0016020 TOLA_RS12415 2e3759a8bdb37585f18bf54a71bac825 226 Pfam PF11444 Protein of unknown function (DUF2895) 6 206 9.5E-89 T 22-04-2016 IPR021548 Protein of unknown function DUF2895 TOLA_RS12415 2e3759a8bdb37585f18bf54a71bac825 226 TIGRFAM TIGR03746 conj_TIGR03746: integrating conjugative element protein, PFL_4703 family 4 207 4.8E-94 T 22-04-2016 IPR021548 Protein of unknown function DUF2895 TOLA_RS06660 53cc23061e685ab1537b312c49af44e1 165 SUPERFAMILY SSF55729 18 147 2.52E-14 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS06660 53cc23061e685ab1537b312c49af44e1 165 PANTHER PTHR36449 1 165 2.1E-41 T 22-04-2016 TOLA_RS06660 53cc23061e685ab1537b312c49af44e1 165 Gene3D G3DSA:3.40.630.30 24 149 1.3E-13 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS06660 53cc23061e685ab1537b312c49af44e1 165 Pfam PF13508 Acetyltransferase (GNAT) domain 42 144 8.2E-9 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS01905 f47ea95deb675c13ea709b75176c16b7 215 Pfam PF13633 Prokaryotic N-terminal methylation site 11 36 2.2E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS01905 f47ea95deb675c13ea709b75176c16b7 215 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 33 3.4E-7 T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS01905 f47ea95deb675c13ea709b75176c16b7 215 PANTHER PTHR39583:SF1 4 202 2.7E-44 T 22-04-2016 TOLA_RS01905 f47ea95deb675c13ea709b75176c16b7 215 Gene3D G3DSA:2.10.70.20 157 204 9.0E-21 T 22-04-2016 TOLA_RS01905 f47ea95deb675c13ea709b75176c16b7 215 Pfam PF11612 Type II secretion system (T2SS), protein J 64 200 2.6E-41 T 22-04-2016 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 TOLA_RS01905 f47ea95deb675c13ea709b75176c16b7 215 TIGRFAM TIGR01711 gspJ: type II secretion system protein J 13 202 2.1E-71 T 22-04-2016 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 TOLA_RS01905 f47ea95deb675c13ea709b75176c16b7 215 PANTHER PTHR39583 4 202 2.7E-44 T 22-04-2016 TOLA_RS01905 f47ea95deb675c13ea709b75176c16b7 215 SUPERFAMILY SSF54523 45 204 5.76E-52 T 22-04-2016 TOLA_RS01905 f47ea95deb675c13ea709b75176c16b7 215 Gene3D G3DSA:3.10.610.10 43 154 1.9E-38 T 22-04-2016 TOLA_RS01905 f47ea95deb675c13ea709b75176c16b7 215 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 22-04-2016 IPR012902 Prokaryotic N-terminal methylation site TOLA_RS01285 258a8e1f4adc217e9d7253911a74c376 184 PIRSF PIRSF038321 1 181 1.0E-88 T 22-04-2016 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 TOLA_RS01285 258a8e1f4adc217e9d7253911a74c376 184 PANTHER PTHR40399 2 182 5.2E-96 T 22-04-2016 TOLA_RS01285 258a8e1f4adc217e9d7253911a74c376 184 TIGRFAM TIGR00821 EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component 1 180 1.6E-101 T 22-04-2016 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 TOLA_RS01285 258a8e1f4adc217e9d7253911a74c376 184 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 6 170 7.6E-76 T 22-04-2016 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 TOLA_RS09525 258a8e1f4adc217e9d7253911a74c376 184 PIRSF PIRSF038321 1 181 1.0E-88 T 22-04-2016 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 TOLA_RS09525 258a8e1f4adc217e9d7253911a74c376 184 PANTHER PTHR40399 2 182 5.2E-96 T 22-04-2016 TOLA_RS09525 258a8e1f4adc217e9d7253911a74c376 184 TIGRFAM TIGR00821 EII-GUT: PTS system, glucitol/sorbitol-specific, IIC component 1 180 1.6E-101 T 22-04-2016 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 TOLA_RS09525 258a8e1f4adc217e9d7253911a74c376 184 Pfam PF03608 PTS system enzyme II sorbitol-specific factor 6 170 7.6E-76 T 22-04-2016 IPR004699 Phosphotransferase system, enzyme II sorbitol-specific factor GO:0009401|GO:0016021 TOLA_RS03450 48a5a1537fb7e276352c0f999d480f6b 325 Gene3D G3DSA:3.40.190.10 20 126 2.1E-27 T 22-04-2016 TOLA_RS03450 48a5a1537fb7e276352c0f999d480f6b 325 Gene3D G3DSA:3.40.190.10 253 283 2.1E-27 T 22-04-2016 TOLA_RS03450 48a5a1537fb7e276352c0f999d480f6b 325 Pfam PF13343 Bacterial extracellular solute-binding protein 74 295 4.8E-13 T 22-04-2016 TOLA_RS03450 48a5a1537fb7e276352c0f999d480f6b 325 SUPERFAMILY SSF53850 21 319 1.67E-56 T 22-04-2016 TOLA_RS03450 48a5a1537fb7e276352c0f999d480f6b 325 TIGRFAM TIGR01276 thiB: thiamin/thiamin pyrophosphate ABC transporter, thiamin/thiamin pyrophospate-binding protein 4 324 2.9E-139 T 22-04-2016 IPR005967 Proteobacterial thiamine ABC transporter, periplasmic binding protein GO:0005524|GO:0015888|GO:0030288|GO:0048502 TOLA_RS03450 48a5a1537fb7e276352c0f999d480f6b 325 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 18 319 5.9E-127 T 22-04-2016 IPR005948 Thiamine ABC transporter periplasmic binding protein GO:0005215|GO:0006810|GO:0015888|GO:0030288|GO:0030975 TOLA_RS03450 48a5a1537fb7e276352c0f999d480f6b 325 PANTHER PTHR30006 15 324 4.5E-111 T 22-04-2016 TOLA_RS03450 48a5a1537fb7e276352c0f999d480f6b 325 Gene3D G3DSA:3.40.190.10 127 252 1.7E-4 T 22-04-2016 TOLA_RS03450 48a5a1537fb7e276352c0f999d480f6b 325 PANTHER PTHR30006:SF3 15 324 4.5E-111 T 22-04-2016 TOLA_RS11905 63275175a166352974a904deecfadacb 154 Pfam PF04319 NifZ domain 2 73 1.9E-29 T 22-04-2016 IPR007415 Nitrogenase MoFe maturation protein, NifZ GO:0009399 TOLA_RS05355 d2a3d813e4e2d94d9ef95ed98dbc14d9 344 Pfam PF06379 L-rhamnose-proton symport protein (RhaT) 2 342 7.4E-144 T 22-04-2016 IPR004673 L-rhamnose-proton symport, RhaT GO:0008645|GO:0015153|GO:0016021 TOLA_RS07220 dd34c18d186d69709d261234137f7186 384 SUPERFAMILY SSF48230 111 355 4.85E-30 T 22-04-2016 IPR008929 Chondroitin AC/alginate lyase TOLA_RS07220 dd34c18d186d69709d261234137f7186 384 Pfam PF05426 Alginate lyase 54 296 5.0E-50 T 22-04-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 TOLA_RS07220 dd34c18d186d69709d261234137f7186 384 Gene3D G3DSA:1.50.10.110 2 355 5.5E-76 T 22-04-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 TOLA_RS05670 252ea288ec17bde57dbe1777facbe5bb 308 Gene3D G3DSA:3.40.190.10 103 199 8.5E-15 T 22-04-2016 TOLA_RS05670 252ea288ec17bde57dbe1777facbe5bb 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 75 1.1E-13 T 22-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TOLA_RS05670 252ea288ec17bde57dbe1777facbe5bb 308 SUPERFAMILY SSF53850 102 306 1.86E-24 T 22-04-2016 TOLA_RS05670 252ea288ec17bde57dbe1777facbe5bb 308 SUPERFAMILY SSF46785 16 98 6.35E-17 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05670 252ea288ec17bde57dbe1777facbe5bb 308 PANTHER PTHR30126 15 305 1.7E-68 T 22-04-2016 TOLA_RS05670 252ea288ec17bde57dbe1777facbe5bb 308 PANTHER PTHR30126:SF16 15 305 1.7E-68 T 22-04-2016 TOLA_RS05670 252ea288ec17bde57dbe1777facbe5bb 308 Pfam PF03466 LysR substrate binding domain 102 303 1.6E-23 T 22-04-2016 IPR005119 LysR, substrate-binding TOLA_RS05670 252ea288ec17bde57dbe1777facbe5bb 308 Gene3D G3DSA:1.10.10.10 16 95 4.7E-20 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14185 de783ca8dd40029bf66beb5b654e7890 245 PANTHER PTHR30616 1 243 2.4E-126 T 22-04-2016 TOLA_RS14185 de783ca8dd40029bf66beb5b654e7890 245 SUPERFAMILY SSF64438 3 241 1.78E-89 T 22-04-2016 IPR011324 Cytotoxic necrotizing factor-like, catalytic TOLA_RS14185 de783ca8dd40029bf66beb5b654e7890 245 PANTHER PTHR30616:SF3 1 243 2.4E-126 T 22-04-2016 TOLA_RS14185 de783ca8dd40029bf66beb5b654e7890 245 Gene3D G3DSA:3.60.140.10 3 241 4.5E-100 T 22-04-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase TOLA_RS14185 de783ca8dd40029bf66beb5b654e7890 245 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 32 241 9.6E-68 T 22-04-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase TOLA_RS14185 de783ca8dd40029bf66beb5b654e7890 245 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 19 240 3.2E-78 T 22-04-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase TOLA_RS14600 bb468b15a2b3f1b3b2024790ee6f762f 89 Gene3D G3DSA:1.20.5.780 2 81 4.4E-19 T 22-04-2016 TOLA_RS14600 bb468b15a2b3f1b3b2024790ee6f762f 89 SUPERFAMILY SSF47598 2 80 3.34E-17 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 TOLA_RS14600 bb468b15a2b3f1b3b2024790ee6f762f 89 Pfam PF08681 Protein of unknown function (DUF1778) 5 81 7.8E-20 T 22-04-2016 IPR014795 Vibrio phage ICP1, Orf50 TOLA_RS15030 06d2f7dba33fd8000fd59ee5e358f9bc 171 Pfam PF02470 MlaD protein 38 117 2.6E-19 T 22-04-2016 IPR003399 Mce/MlaD TOLA_RS15030 06d2f7dba33fd8000fd59ee5e358f9bc 171 PANTHER PTHR33371 1 152 2.5E-45 T 22-04-2016 TOLA_RS15030 06d2f7dba33fd8000fd59ee5e358f9bc 171 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 4 152 1.0E-54 T 22-04-2016 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 TOLA_RS05530 5d4f23b2dd8c749b3f139127a8bfae9d 119 Pfam PF01740 STAS domain 3 94 1.6E-13 T 22-04-2016 IPR002645 STAS domain TOLA_RS05530 5d4f23b2dd8c749b3f139127a8bfae9d 119 Gene3D G3DSA:3.30.750.24 3 103 1.1E-22 T 22-04-2016 IPR002645 STAS domain TOLA_RS05530 5d4f23b2dd8c749b3f139127a8bfae9d 119 SUPERFAMILY SSF52091 2 97 1.53E-19 T 22-04-2016 IPR002645 STAS domain TOLA_RS05530 5d4f23b2dd8c749b3f139127a8bfae9d 119 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 3 93 1.4E-15 T 22-04-2016 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 TOLA_RS05530 5d4f23b2dd8c749b3f139127a8bfae9d 119 PANTHER PTHR33495 1 106 3.7E-16 T 22-04-2016 TOLA_RS08850 344c838d6453a85cbb6d24e915180f47 257 Gene3D G3DSA:3.20.20.70 4 256 8.1E-86 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS08850 344c838d6453a85cbb6d24e915180f47 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 256 4.3E-111 T 22-04-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 TOLA_RS08850 344c838d6453a85cbb6d24e915180f47 257 PANTHER PTHR21235:SF2 1 257 6.0E-111 T 22-04-2016 TOLA_RS08850 344c838d6453a85cbb6d24e915180f47 257 SUPERFAMILY SSF51366 1 256 7.38E-71 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TOLA_RS08850 344c838d6453a85cbb6d24e915180f47 257 Pfam PF00977 Histidine biosynthesis protein 5 239 2.1E-75 T 22-04-2016 IPR006062 Histidine biosynthesis GO:0000105 TOLA_RS08850 344c838d6453a85cbb6d24e915180f47 257 PANTHER PTHR21235 1 257 6.0E-111 T 22-04-2016 TOLA_RS08850 344c838d6453a85cbb6d24e915180f47 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 256 43.821 T 22-04-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 TOLA_RS14520 58d120150d285bae8afb672488ec60e3 413 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 303 393 4.6E-22 T 22-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS14520 58d120150d285bae8afb672488ec60e3 413 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 85 96 2.5E-16 T 22-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TOLA_RS14520 58d120150d285bae8afb672488ec60e3 413 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 141 158 2.5E-16 T 22-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TOLA_RS14520 58d120150d285bae8afb672488ec60e3 413 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 168 181 2.5E-16 T 22-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 TOLA_RS14520 58d120150d285bae8afb672488ec60e3 413 PANTHER PTHR21581 52 413 1.2E-151 T 22-04-2016 TOLA_RS14520 58d120150d285bae8afb672488ec60e3 413 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 52 282 1.8E-87 T 22-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 TOLA_RS14520 58d120150d285bae8afb672488ec60e3 413 Gene3D G3DSA:3.40.710.10 49 302 7.9E-96 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS14520 58d120150d285bae8afb672488ec60e3 413 Gene3D G3DSA:2.60.410.10 303 393 1.5E-27 T 22-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS14520 58d120150d285bae8afb672488ec60e3 413 SUPERFAMILY SSF56601 2 303 5.0E-82 T 22-04-2016 IPR012338 Beta-lactamase/transpeptidase-like TOLA_RS14520 58d120150d285bae8afb672488ec60e3 413 PANTHER PTHR21581:SF4 52 413 1.2E-151 T 22-04-2016 TOLA_RS14520 58d120150d285bae8afb672488ec60e3 413 SMART SM00936 303 393 1.8E-29 T 22-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS14520 58d120150d285bae8afb672488ec60e3 413 SUPERFAMILY SSF69189 303 395 1.92E-23 T 22-04-2016 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS04685 0c596817d020f859482f3def96509969 249 Pfam PF00929 Exonuclease 10 176 9.6E-39 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III TOLA_RS04685 0c596817d020f859482f3def96509969 249 PANTHER PTHR30231 4 249 2.9E-125 T 22-04-2016 TOLA_RS04685 0c596817d020f859482f3def96509969 249 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 8 228 3.9E-78 T 22-04-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS04685 0c596817d020f859482f3def96509969 249 SMART SM00479 8 185 7.8E-52 T 22-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III TOLA_RS04685 0c596817d020f859482f3def96509969 249 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 8 245 2.4E-95 T 22-04-2016 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS04685 0c596817d020f859482f3def96509969 249 PANTHER PTHR30231:SF0 4 249 2.9E-125 T 22-04-2016 TOLA_RS04685 0c596817d020f859482f3def96509969 249 Gene3D G3DSA:3.30.420.10 3 187 7.5E-65 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS04685 0c596817d020f859482f3def96509969 249 SUPERFAMILY SSF53098 4 186 3.08E-55 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS03580 11e5371c7ee93d1b8e0a75beeeb2314f 157 PANTHER PTHR41377 3 151 1.3E-56 T 22-04-2016 TOLA_RS03580 11e5371c7ee93d1b8e0a75beeeb2314f 157 PIRSF PIRSF008546 7 148 5.3E-56 T 22-04-2016 IPR014937 Protein of unknown function DUF1810 TOLA_RS03580 11e5371c7ee93d1b8e0a75beeeb2314f 157 PANTHER PTHR41377:SF1 3 151 1.3E-56 T 22-04-2016 TOLA_RS03580 11e5371c7ee93d1b8e0a75beeeb2314f 157 SUPERFAMILY SSF140736 12 146 6.15E-55 T 22-04-2016 TOLA_RS03580 11e5371c7ee93d1b8e0a75beeeb2314f 157 Pfam PF08837 Protein of unknown function (DUF1810) 12 145 2.6E-56 T 22-04-2016 IPR014937 Protein of unknown function DUF1810 TOLA_RS03960 8c17bfc5af0cbc1034f4561ec35eb39c 259 Pfam PF02535 ZIP Zinc transporter 113 254 3.7E-19 T 22-04-2016 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 TOLA_RS03960 8c17bfc5af0cbc1034f4561ec35eb39c 259 PANTHER PTHR11040:SF33 3 259 4.1E-71 T 22-04-2016 TOLA_RS03960 8c17bfc5af0cbc1034f4561ec35eb39c 259 PANTHER PTHR11040 3 259 4.1E-71 T 22-04-2016 TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 PRINTS PR00811 Bacterial general secretion pathway protein D signature 444 468 4.7E-39 T 22-04-2016 IPR001775 GspD/PilQ family TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 PRINTS PR00811 Bacterial general secretion pathway protein D signature 364 374 4.7E-39 T 22-04-2016 IPR001775 GspD/PilQ family TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 PRINTS PR00811 Bacterial general secretion pathway protein D signature 606 620 4.7E-39 T 22-04-2016 IPR001775 GspD/PilQ family TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 PRINTS PR00811 Bacterial general secretion pathway protein D signature 479 489 4.7E-39 T 22-04-2016 IPR001775 GspD/PilQ family TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 PRINTS PR00811 Bacterial general secretion pathway protein D signature 583 601 4.7E-39 T 22-04-2016 IPR001775 GspD/PilQ family TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 Pfam PF00263 Bacterial type II and III secretion system protein 448 619 5.5E-52 T 22-04-2016 IPR004846 Type II/III secretion system GO:0009306 TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 Pfam PF03958 Bacterial type II/III secretion system short domain 127 186 8.8E-11 T 22-04-2016 IPR005644 NolW-like TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 Pfam PF03958 Bacterial type II/III secretion system short domain 192 260 7.7E-13 T 22-04-2016 IPR005644 NolW-like TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 Pfam PF03958 Bacterial type II/III secretion system short domain 266 364 4.1E-20 T 22-04-2016 IPR005644 NolW-like TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 31 626 3.9E-176 T 22-04-2016 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 564 597 - T 22-04-2016 IPR004845 Type II secretion system GspD, conserved site GO:0008565 TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 PANTHER PTHR30332 26 658 6.6E-265 T 22-04-2016 TOLA_RS01935 d042da6438a8ae03453d0c0eabe69cb1 685 PANTHER PTHR30332:SF3 26 658 6.6E-265 T 22-04-2016 TOLA_RS12425 28b8d2ba6d75f790a9947a0fd229938c 469 TIGRFAM TIGR03752 conj_TIGR03752: integrating conjugative element protein, PFL_4705 family 2 459 1.2E-182 T 22-04-2016 IPR021207 Integrating conjugative element protein, PFL4705 TOLA_RS00875 c6aec0d6ae11d6499d1fc8183474bc4b 135 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 11 132 8.3E-42 T 22-04-2016 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 TOLA_RS00875 c6aec0d6ae11d6499d1fc8183474bc4b 135 PANTHER PTHR11644 11 135 1.1E-54 T 22-04-2016 TOLA_RS00875 c6aec0d6ae11d6499d1fc8183474bc4b 135 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 10 103 6.0E-16 T 22-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 TOLA_RS00875 c6aec0d6ae11d6499d1fc8183474bc4b 135 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 59 98 - T 22-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TOLA_RS00875 c6aec0d6ae11d6499d1fc8183474bc4b 135 Gene3D G3DSA:3.40.140.10 5 134 5.0E-47 T 22-04-2016 TOLA_RS00875 c6aec0d6ae11d6499d1fc8183474bc4b 135 SUPERFAMILY SSF53927 9 133 2.01E-41 T 22-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 TOLA_RS16380 c9b879bbce32f5e22c7948c963e560ce 161 SUPERFAMILY SSF55729 7 137 1.46E-22 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS16380 c9b879bbce32f5e22c7948c963e560ce 161 PANTHER PTHR13256 7 143 1.8E-18 T 22-04-2016 TOLA_RS16380 c9b879bbce32f5e22c7948c963e560ce 161 Pfam PF13302 Acetyltransferase (GNAT) domain 6 133 1.0E-19 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS16380 c9b879bbce32f5e22c7948c963e560ce 161 Gene3D G3DSA:3.40.630.30 4 142 3.2E-24 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS13620 49e7daf4adbcaaf2f3e07471944b7d1b 913 Pfam PF13362 Toprim domain 223 316 4.0E-14 T 22-04-2016 IPR006171 Toprim domain TOLA_RS13620 49e7daf4adbcaaf2f3e07471944b7d1b 913 SMART SM00778 33 72 8.7E-17 T 22-04-2016 IPR013237 Bacteriophage T7, Gp4, DNA primase/helicase, N-terminal GO:0003896|GO:0004386|GO:0008270 KEGG: 00520+2.7.7.- TOLA_RS13620 49e7daf4adbcaaf2f3e07471944b7d1b 913 Pfam PF06048 Domain of unknown function (DUF927) 362 637 3.7E-58 T 22-04-2016 IPR009270 Domain of unknown function DUF927 TOLA_RS13620 49e7daf4adbcaaf2f3e07471944b7d1b 913 Pfam PF08273 Zinc-binding domain of primase-helicase 33 72 5.8E-17 T 22-04-2016 IPR013237 Bacteriophage T7, Gp4, DNA primase/helicase, N-terminal GO:0003896|GO:0004386|GO:0008270 KEGG: 00520+2.7.7.- TOLA_RS13620 49e7daf4adbcaaf2f3e07471944b7d1b 913 SUPERFAMILY SSF57783 32 97 4.08E-6 T 22-04-2016 TOLA_RS13620 49e7daf4adbcaaf2f3e07471944b7d1b 913 Gene3D G3DSA:3.40.1360.10 214 325 7.1E-6 T 22-04-2016 TOLA_RS10015 b05780c37d1f26b518b9b84156c16f16 250 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 8 225 2.3E-67 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TOLA_RS10015 b05780c37d1f26b518b9b84156c16f16 250 PANTHER PTHR30371:SF0 7 237 8.1E-90 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TOLA_RS10015 b05780c37d1f26b518b9b84156c16f16 250 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 220 2.7E-60 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TOLA_RS10015 b05780c37d1f26b518b9b84156c16f16 250 PANTHER PTHR30371 7 237 8.1E-90 T 22-04-2016 TOLA_RS10015 b05780c37d1f26b518b9b84156c16f16 250 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 237 17.302 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TOLA_RS10015 b05780c37d1f26b518b9b84156c16f16 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 84 102 1.4E-42 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TOLA_RS10015 b05780c37d1f26b518b9b84156c16f16 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 7 34 1.4E-42 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TOLA_RS10015 b05780c37d1f26b518b9b84156c16f16 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 153 181 1.4E-42 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TOLA_RS10015 b05780c37d1f26b518b9b84156c16f16 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 102 128 1.4E-42 T 22-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TOLA_RS04825 e8b245b725e85fd993574a9be62b4f95 397 Gene3D G3DSA:3.40.50.1100 176 392 4.3E-93 T 22-04-2016 TOLA_RS04825 e8b245b725e85fd993574a9be62b4f95 397 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 390 50.083 T 22-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 TOLA_RS04825 e8b245b725e85fd993574a9be62b4f95 397 Gene3D G3DSA:3.40.50.1100 96 175 3.2E-21 T 22-04-2016 TOLA_RS04825 e8b245b725e85fd993574a9be62b4f95 397 PIRSF PIRSF001413 2 395 2.8E-166 T 22-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 TOLA_RS04825 e8b245b725e85fd993574a9be62b4f95 397 SUPERFAMILY SSF53686 5 388 5.76E-144 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TOLA_RS04825 e8b245b725e85fd993574a9be62b4f95 397 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 79 93 - T 22-04-2016 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 TOLA_RS04825 e8b245b725e85fd993574a9be62b4f95 397 PANTHER PTHR10314 6 391 7.1E-226 T 22-04-2016 TOLA_RS04825 e8b245b725e85fd993574a9be62b4f95 397 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 7 389 2.8E-188 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 TOLA_RS04825 e8b245b725e85fd993574a9be62b4f95 397 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 51 373 1.0E-51 T 22-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TOLA_RS04825 e8b245b725e85fd993574a9be62b4f95 397 PANTHER PTHR10314:SF3 6 391 7.1E-226 T 22-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 TOLA_RS12160 e92c986a3f1a2f9f1023ab93cf832e9d 247 Pfam PF00480 ROK family 4 165 4.5E-23 T 22-04-2016 IPR000600 ROK family TOLA_RS12160 e92c986a3f1a2f9f1023ab93cf832e9d 247 Gene3D G3DSA:3.30.420.40 105 245 1.3E-34 T 22-04-2016 TOLA_RS12160 e92c986a3f1a2f9f1023ab93cf832e9d 247 PANTHER PTHR18964 1 246 7.6E-56 T 22-04-2016 TOLA_RS12160 e92c986a3f1a2f9f1023ab93cf832e9d 247 SUPERFAMILY SSF53067 1 245 1.09E-37 T 22-04-2016 TOLA_RS12160 e92c986a3f1a2f9f1023ab93cf832e9d 247 PANTHER PTHR18964:SF138 1 246 7.6E-56 T 22-04-2016 TOLA_RS12160 e92c986a3f1a2f9f1023ab93cf832e9d 247 Gene3D G3DSA:3.30.420.40 1 104 1.9E-37 T 22-04-2016 TOLA_RS14055 c9c00b13b7c0f85598476d8c5573c990 462 Gene3D G3DSA:1.10.10.10 9 79 1.5E-24 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14055 c9c00b13b7c0f85598476d8c5573c990 462 PANTHER PTHR11751:SF413 78 433 1.2E-58 T 22-04-2016 TOLA_RS14055 c9c00b13b7c0f85598476d8c5573c990 462 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 1.6E-16 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS14055 c9c00b13b7c0f85598476d8c5573c990 462 Gene3D G3DSA:3.40.640.10 129 346 2.5E-49 T 22-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TOLA_RS14055 c9c00b13b7c0f85598476d8c5573c990 462 PANTHER PTHR11751 78 433 1.2E-58 T 22-04-2016 TOLA_RS14055 c9c00b13b7c0f85598476d8c5573c990 462 SMART SM00345 18 77 2.6E-18 T 22-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TOLA_RS14055 c9c00b13b7c0f85598476d8c5573c990 462 Pfam PF00155 Aminotransferase class I and II 119 438 3.6E-18 T 22-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TOLA_RS14055 c9c00b13b7c0f85598476d8c5573c990 462 SUPERFAMILY SSF53383 81 453 1.57E-67 T 22-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase TOLA_RS14055 c9c00b13b7c0f85598476d8c5573c990 462 SUPERFAMILY SSF46785 9 86 3.2E-19 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02770 e38014fb0eb2a03870f9c9faf26d06d8 291 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 21 128 7.8E-33 T 22-04-2016 IPR010627 Peptidase A24A, N-terminal KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- TOLA_RS02770 e38014fb0eb2a03870f9c9faf26d06d8 291 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 228 243 3.6E-29 T 22-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- TOLA_RS02770 e38014fb0eb2a03870f9c9faf26d06d8 291 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 216 227 3.6E-29 T 22-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- TOLA_RS02770 e38014fb0eb2a03870f9c9faf26d06d8 291 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 148 165 3.6E-29 T 22-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- TOLA_RS02770 e38014fb0eb2a03870f9c9faf26d06d8 291 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 205 215 3.6E-29 T 22-04-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- TOLA_RS02770 e38014fb0eb2a03870f9c9faf26d06d8 291 PANTHER PTHR30487 3 39 2.8E-107 T 22-04-2016 TOLA_RS02770 e38014fb0eb2a03870f9c9faf26d06d8 291 PANTHER PTHR30487 62 288 2.8E-107 T 22-04-2016 TOLA_RS02770 e38014fb0eb2a03870f9c9faf26d06d8 291 Pfam PF01478 Type IV leader peptidase family 139 248 1.2E-28 T 22-04-2016 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 TOLA_RS02770 e38014fb0eb2a03870f9c9faf26d06d8 291 PANTHER PTHR30487:SF0 3 39 2.8E-107 T 22-04-2016 TOLA_RS02770 e38014fb0eb2a03870f9c9faf26d06d8 291 PANTHER PTHR30487:SF0 62 288 2.8E-107 T 22-04-2016 TOLA_RS06895 4a8bf2cd66c55c98298c30dc0f82aff4 312 PANTHER PTHR36698:SF2 2 312 2.8E-80 T 22-04-2016 TOLA_RS06895 4a8bf2cd66c55c98298c30dc0f82aff4 312 PANTHER PTHR36698 2 312 2.8E-80 T 22-04-2016 TOLA_RS06895 4a8bf2cd66c55c98298c30dc0f82aff4 312 Pfam PF02470 MlaD protein 42 113 1.7E-12 T 22-04-2016 IPR003399 Mce/MlaD TOLA_RS01150 f8df5f620fa05e82c4c4e51a98aeaf87 240 PIRSF PIRSF006171 1 231 2.5E-82 T 22-04-2016 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 TOLA_RS01150 f8df5f620fa05e82c4c4e51a98aeaf87 240 SUPERFAMILY SSF52172 3 165 5.83E-33 T 22-04-2016 IPR011006 CheY-like superfamily TOLA_RS01150 f8df5f620fa05e82c4c4e51a98aeaf87 240 SMART SM00448 2 117 1.3E-26 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS01150 f8df5f620fa05e82c4c4e51a98aeaf87 240 Pfam PF00072 Response regulator receiver domain 4 117 1.1E-23 T 22-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 TOLA_RS01150 f8df5f620fa05e82c4c4e51a98aeaf87 240 Gene3D G3DSA:3.40.50.2300 2 136 7.8E-29 T 22-04-2016 TOLA_RS01150 f8df5f620fa05e82c4c4e51a98aeaf87 240 PANTHER PTHR26402:SF522 2 189 1.0E-54 T 22-04-2016 TOLA_RS01150 f8df5f620fa05e82c4c4e51a98aeaf87 240 PANTHER PTHR26402 2 189 1.0E-54 T 22-04-2016 TOLA_RS14580 aaa95dbc1947ef49e938d91c708c21a3 80 Gene3D G3DSA:3.40.1620.10 1 49 4.5E-5 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TOLA_RS14580 aaa95dbc1947ef49e938d91c708c21a3 80 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 69 4.6E-18 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TOLA_RS14580 aaa95dbc1947ef49e938d91c708c21a3 80 SUPERFAMILY SSF143120 1 80 4.05E-20 T 22-04-2016 TOLA_RS14580 aaa95dbc1947ef49e938d91c708c21a3 80 PANTHER PTHR33713:SF6 1 69 3.3E-16 T 22-04-2016 TOLA_RS14580 aaa95dbc1947ef49e938d91c708c21a3 80 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 54 3.3E-8 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TOLA_RS14580 aaa95dbc1947ef49e938d91c708c21a3 80 PANTHER PTHR33713 1 69 3.3E-16 T 22-04-2016 TOLA_RS08000 ca10bcad9b95719d9e1b1dd90308360b 685 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 641 684 2.9E-12 T 22-04-2016 IPR020011 Motility protein FimV, C-terminal TOLA_RS08000 ca10bcad9b95719d9e1b1dd90308360b 685 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 71 144 1.2E-14 T 22-04-2016 IPR020012 Motility protein FimV, N-terminal TOLA_RS10975 3b0de04bbdb108689abea5bde1e12a60 232 SUPERFAMILY SSF53639 3 221 1.96E-67 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal TOLA_RS10975 3b0de04bbdb108689abea5bde1e12a60 232 Gene3D G3DSA:3.40.225.10 3 229 2.6E-69 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal TOLA_RS10975 3b0de04bbdb108689abea5bde1e12a60 232 PANTHER PTHR22789 3 229 2.1E-125 T 22-04-2016 TOLA_RS10975 3b0de04bbdb108689abea5bde1e12a60 232 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 195 1.3E-43 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal TOLA_RS10975 3b0de04bbdb108689abea5bde1e12a60 232 SMART SM01007 8 196 4.3E-66 T 22-04-2016 IPR001303 Class II aldolase/adducin N-terminal TOLA_RS10975 3b0de04bbdb108689abea5bde1e12a60 232 PANTHER PTHR22789:SF8 3 229 2.1E-125 T 22-04-2016 TOLA_RS02110 b8b5163d4ca4fdc63e3fc22a58449d49 172 PANTHER PTHR33164 4 171 1.8E-33 T 22-04-2016 TOLA_RS02110 b8b5163d4ca4fdc63e3fc22a58449d49 172 SMART SM00347 44 147 1.4E-24 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS02110 b8b5163d4ca4fdc63e3fc22a58449d49 172 PANTHER PTHR33164:SF4 4 171 1.8E-33 T 22-04-2016 TOLA_RS02110 b8b5163d4ca4fdc63e3fc22a58449d49 172 Gene3D G3DSA:1.10.10.10 10 163 1.0E-39 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02110 b8b5163d4ca4fdc63e3fc22a58449d49 172 Pfam PF01047 MarR family 51 111 9.0E-15 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS02110 b8b5163d4ca4fdc63e3fc22a58449d49 172 ProSitePatterns PS01117 MarR-type HTH domain signature. 86 120 - T 22-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site TOLA_RS02110 b8b5163d4ca4fdc63e3fc22a58449d49 172 SUPERFAMILY SSF46785 10 161 7.49E-35 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS02110 b8b5163d4ca4fdc63e3fc22a58449d49 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 87 8.3E-10 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS02110 b8b5163d4ca4fdc63e3fc22a58449d49 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 123 8.3E-10 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS02110 b8b5163d4ca4fdc63e3fc22a58449d49 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 103 8.3E-10 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS02110 b8b5163d4ca4fdc63e3fc22a58449d49 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 137 157 8.3E-10 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS08210 6045ec9e08a3f208d875a25f1d0cac79 1038 SUPERFAMILY SSF56349 401 641 2.88E-11 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TOLA_RS08210 6045ec9e08a3f208d875a25f1d0cac79 1038 Gene3D G3DSA:1.10.443.10 493 713 4.5E-9 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS00710 fab04611a344e33f57e536a09ab9dc35 371 SUPERFAMILY SSF53822 27 365 1.45E-89 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS00710 fab04611a344e33f57e536a09ab9dc35 371 Pfam PF13458 Periplasmic binding protein 28 365 1.5E-58 T 22-04-2016 IPR028081 Leucine-binding protein domain TOLA_RS00710 fab04611a344e33f57e536a09ab9dc35 371 PANTHER PTHR30483:SF16 1 361 6.0E-175 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TOLA_RS00710 fab04611a344e33f57e536a09ab9dc35 371 Gene3D G3DSA:3.40.50.2300 27 227 1.5E-65 T 22-04-2016 TOLA_RS00710 fab04611a344e33f57e536a09ab9dc35 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 3.6E-51 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TOLA_RS00710 fab04611a344e33f57e536a09ab9dc35 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 3.6E-51 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TOLA_RS00710 fab04611a344e33f57e536a09ab9dc35 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 257 275 3.6E-51 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TOLA_RS00710 fab04611a344e33f57e536a09ab9dc35 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 280 293 3.6E-51 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TOLA_RS00710 fab04611a344e33f57e536a09ab9dc35 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 331 346 3.6E-51 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TOLA_RS00710 fab04611a344e33f57e536a09ab9dc35 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 91 101 3.6E-51 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TOLA_RS00710 fab04611a344e33f57e536a09ab9dc35 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 70 88 3.6E-51 T 22-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TOLA_RS00710 fab04611a344e33f57e536a09ab9dc35 371 PANTHER PTHR30483 1 361 6.0E-175 T 22-04-2016 TOLA_RS01125 22fc6cd11323da2f7a3f5780156ecb00 536 Pfam PF04262 Glutamate-cysteine ligase 12 385 1.3E-161 T 22-04-2016 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA00142 TOLA_RS01125 22fc6cd11323da2f7a3f5780156ecb00 536 SUPERFAMILY SSF55931 9 520 4.58E-189 T 22-04-2016 TOLA_RS01125 22fc6cd11323da2f7a3f5780156ecb00 536 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 22 522 4.1E-191 T 22-04-2016 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA00142 TOLA_RS01125 22fc6cd11323da2f7a3f5780156ecb00 536 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 536 207.605 T 22-04-2016 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA00142 TOLA_RS01125 22fc6cd11323da2f7a3f5780156ecb00 536 PANTHER PTHR38761 4 530 4.7E-239 T 22-04-2016 TOLA_RS14845 56789792cbde4bf1ab73c866114472c8 600 SUPERFAMILY SSF75304 5 445 1.96E-108 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TOLA_RS14845 56789792cbde4bf1ab73c866114472c8 600 Pfam PF01425 Amidase 24 437 1.3E-78 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TOLA_RS14845 56789792cbde4bf1ab73c866114472c8 600 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 38 595 1.9E-243 T 22-04-2016 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 TOLA_RS14845 56789792cbde4bf1ab73c866114472c8 600 Gene3D G3DSA:3.90.1300.10 5 448 4.0E-106 T 22-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TOLA_RS14845 56789792cbde4bf1ab73c866114472c8 600 PANTHER PTHR11895 5 454 1.4E-180 T 22-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TOLA_RS14845 56789792cbde4bf1ab73c866114472c8 600 Gene3D G3DSA:3.10.490.10 475 543 1.9E-5 T 22-04-2016 IPR013024 Butirosin biosynthesis, BtrG-like TOLA_RS14845 56789792cbde4bf1ab73c866114472c8 600 PANTHER PTHR11895:SF24 5 454 1.4E-180 T 22-04-2016 TOLA_RS01955 068439611924cdcce4d2dc97dfcb98bd 234 SUPERFAMILY SSF51445 91 191 1.29E-8 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS01955 068439611924cdcce4d2dc97dfcb98bd 234 Pfam PF11340 Protein of unknown function (DUF3142) 87 178 3.5E-16 T 22-04-2016 IPR021488 Protein of unknown function DUF3142 TOLA_RS01955 068439611924cdcce4d2dc97dfcb98bd 234 Gene3D G3DSA:3.20.20.80 113 190 1.4E-5 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS05675 567985e98746c62a5b92876a6ea5c1e9 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 259 8.0E-15 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05675 567985e98746c62a5b92876a6ea5c1e9 274 Gene3D G3DSA:1.10.3720.10 19 268 3.8E-58 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05675 567985e98746c62a5b92876a6ea5c1e9 274 PANTHER PTHR30193 23 274 4.0E-85 T 22-04-2016 TOLA_RS05675 567985e98746c62a5b92876a6ea5c1e9 274 PANTHER PTHR30193:SF20 23 274 4.0E-85 T 22-04-2016 TOLA_RS05675 567985e98746c62a5b92876a6ea5c1e9 274 SUPERFAMILY SSF161098 11 266 6.17E-58 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS15105 94d8493f905e9d519cf087de7ed20c60 258 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 8 250 6.9E-78 T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 TOLA_RS15105 94d8493f905e9d519cf087de7ed20c60 258 PANTHER PTHR30589:SF0 1 258 3.0E-77 T 22-04-2016 TOLA_RS15105 94d8493f905e9d519cf087de7ed20c60 258 PANTHER PTHR30589 1 258 3.0E-77 T 22-04-2016 TOLA_RS15105 94d8493f905e9d519cf087de7ed20c60 258 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 TOLA_RS15105 94d8493f905e9d519cf087de7ed20c60 258 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 256 6.7E-54 T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 TOLA_RS15105 94d8493f905e9d519cf087de7ed20c60 258 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 5 256 17.461 T 22-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 TOLA_RS15010 cabb9ac267e0479f165b54aaae245af5 419 Gene3D G3DSA:3.65.10.10 220 416 9.5E-61 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 TOLA_RS15010 cabb9ac267e0479f165b54aaae245af5 419 PANTHER PTHR21090 1 419 2.6E-221 T 22-04-2016 TOLA_RS15010 cabb9ac267e0479f165b54aaae245af5 419 Gene3D G3DSA:3.65.10.10 21 219 3.8E-69 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 TOLA_RS15010 cabb9ac267e0479f165b54aaae245af5 419 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 4.1E-183 T 22-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS15010 cabb9ac267e0479f165b54aaae245af5 419 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 46.528 T 22-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 TOLA_RS15010 cabb9ac267e0479f165b54aaae245af5 419 SUPERFAMILY SSF55205 1 418 3.53E-145 T 22-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TOLA_RS15010 cabb9ac267e0479f165b54aaae245af5 419 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 405 3.8E-128 T 22-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 TOLA_RS16215 622692c6ad65c07b9f9e9511e9e812e3 261 Pfam PF00121 Triosephosphate isomerase 4 251 2.5E-81 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 TOLA_RS16215 622692c6ad65c07b9f9e9511e9e812e3 261 SUPERFAMILY SSF51351 1 255 5.11E-80 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 TOLA_RS16215 622692c6ad65c07b9f9e9511e9e812e3 261 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 241 2.2E-47 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 TOLA_RS16215 622692c6ad65c07b9f9e9511e9e812e3 261 PANTHER PTHR21139 1 258 7.3E-85 T 22-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 TOLA_RS16215 622692c6ad65c07b9f9e9511e9e812e3 261 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 255 34.08 T 22-04-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 TOLA_RS16215 622692c6ad65c07b9f9e9511e9e812e3 261 PANTHER PTHR21139:SF2 1 258 7.3E-85 T 22-04-2016 TOLA_RS16215 622692c6ad65c07b9f9e9511e9e812e3 261 Gene3D G3DSA:3.20.20.70 1 257 2.3E-88 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS05100 d67fd7aa3ea6f08497d3dbdb7f804035 204 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 89 - T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TOLA_RS05100 d67fd7aa3ea6f08497d3dbdb7f804035 204 Pfam PF01066 CDP-alcohol phosphatidyltransferase 28 89 4.4E-8 T 22-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TOLA_RS10885 2245672590b76ddfae0e2ece3d97d20c 486 Gene3D G3DSA:2.60.120.560 299 461 6.0E-11 T 22-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal TOLA_RS10885 2245672590b76ddfae0e2ece3d97d20c 486 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 12 25 - T 22-04-2016 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 TOLA_RS10885 2245672590b76ddfae0e2ece3d97d20c 486 Gene3D G3DSA:2.130.10.140 66 254 5.6E-8 T 22-04-2016 TOLA_RS10885 2245672590b76ddfae0e2ece3d97d20c 486 SMART SM00640 12 446 1.2E-119 T 22-04-2016 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 TOLA_RS10885 2245672590b76ddfae0e2ece3d97d20c 486 Gene3D G3DSA:2.115.10.20 18 65 2.4E-4 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain TOLA_RS10885 2245672590b76ddfae0e2ece3d97d20c 486 SUPERFAMILY SSF75005 4 323 5.02E-100 T 22-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain TOLA_RS10885 2245672590b76ddfae0e2ece3d97d20c 486 PANTHER PTHR30175 4 465 6.5E-120 T 22-04-2016 TOLA_RS10885 2245672590b76ddfae0e2ece3d97d20c 486 PANTHER PTHR30175:SF0 4 465 6.5E-120 T 22-04-2016 TOLA_RS10885 2245672590b76ddfae0e2ece3d97d20c 486 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 12 320 2.0E-95 T 22-04-2016 IPR013148 Glycosyl hydrolase family 32, N-terminal TOLA_RS10885 2245672590b76ddfae0e2ece3d97d20c 486 SUPERFAMILY SSF49899 344 463 1.66E-8 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain TOLA_RS09785 f2b47a8af60ecfc4bdf418e3eeb36f30 71 Gene3D G3DSA:1.10.10.60 13 67 6.9E-25 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS09785 f2b47a8af60ecfc4bdf418e3eeb36f30 71 PANTHER PTHR32071 13 70 4.4E-21 T 22-04-2016 TOLA_RS09785 f2b47a8af60ecfc4bdf418e3eeb36f30 71 PANTHER PTHR32071:SF3 13 70 4.4E-21 T 22-04-2016 TOLA_RS09785 f2b47a8af60ecfc4bdf418e3eeb36f30 71 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 19 67 7.8E-28 T 22-04-2016 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 TOLA_RS09785 f2b47a8af60ecfc4bdf418e3eeb36f30 71 SUPERFAMILY SSF46689 12 66 3.99E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS04715 099f243a3030c1744b96f3410c3089d3 233 Gene3D G3DSA:1.10.8.60 167 232 2.9E-28 T 22-04-2016 TOLA_RS04715 099f243a3030c1744b96f3410c3089d3 233 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 43 63 3.4E-5 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like TOLA_RS04715 099f243a3030c1744b96f3410c3089d3 233 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 131 158 3.4E-5 T 22-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like TOLA_RS04715 099f243a3030c1744b96f3410c3089d3 233 Gene3D G3DSA:3.40.50.300 4 163 7.3E-39 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04715 099f243a3030c1744b96f3410c3089d3 233 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 6 232 3.8E-85 T 22-04-2016 IPR017788 DnaA regulatory inactivator Hda GO:0032297 TOLA_RS04715 099f243a3030c1744b96f3410c3089d3 233 PANTHER PTHR30050:SF5 1 232 8.4E-94 T 22-04-2016 TOLA_RS04715 099f243a3030c1744b96f3410c3089d3 233 SUPERFAMILY SSF52540 13 211 2.95E-25 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS04715 099f243a3030c1744b96f3410c3089d3 233 PANTHER PTHR30050 1 232 8.4E-94 T 22-04-2016 TOLA_RS04715 099f243a3030c1744b96f3410c3089d3 233 Pfam PF00308 Bacterial dnaA protein 17 212 4.9E-13 T 22-04-2016 IPR013317 Chromosomal replication initiator protein DnaA TOLA_RS05520 519fc9dbd20e070d94e24ee3985444dd 259 Gene3D G3DSA:3.20.20.70 3 255 7.0E-63 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS05520 519fc9dbd20e070d94e24ee3985444dd 259 PANTHER PTHR34266:SF2 1 259 4.7E-151 T 22-04-2016 TOLA_RS05520 519fc9dbd20e070d94e24ee3985444dd 259 Pfam PF05690 Thiazole biosynthesis protein ThiG 6 250 8.3E-109 T 22-04-2016 TOLA_RS05520 519fc9dbd20e070d94e24ee3985444dd 259 PANTHER PTHR34266 1 259 4.7E-151 T 22-04-2016 TOLA_RS05520 519fc9dbd20e070d94e24ee3985444dd 259 SUPERFAMILY SSF110399 4 238 1.01E-83 T 22-04-2016 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892|UniPathway: UPA00060 TOLA_RS05520 519fc9dbd20e070d94e24ee3985444dd 259 Hamap MF_00443 Thiazole synthase [thiG]. 4 256 42.258 T 22-04-2016 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892|UniPathway: UPA00060 TOLA_RS10825 0cbf11a0a492632ed6abffa51cd7b1b0 96 PANTHER PTHR37828 1 96 2.4E-20 T 22-04-2016 TOLA_RS10825 0cbf11a0a492632ed6abffa51cd7b1b0 96 Gene3D G3DSA:3.30.70.1060 2 83 1.5E-7 T 22-04-2016 TOLA_RS10825 0cbf11a0a492632ed6abffa51cd7b1b0 96 PANTHER PTHR37828:SF1 1 96 2.4E-20 T 22-04-2016 TOLA_RS10825 0cbf11a0a492632ed6abffa51cd7b1b0 96 SUPERFAMILY SSF54909 1 84 1.56E-17 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel TOLA_RS10825 0cbf11a0a492632ed6abffa51cd7b1b0 96 Pfam PF03795 YCII-related domain 6 81 1.6E-10 T 22-04-2016 IPR005545 YCII-related TOLA_RS00145 e79451e37577ccf826a02f25fcdc3684 265 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 91 190 5.4E-8 T 22-04-2016 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 TOLA_RS00145 e79451e37577ccf826a02f25fcdc3684 265 SUPERFAMILY SSF56112 33 192 1.12E-8 T 22-04-2016 IPR011009 Protein kinase-like domain TOLA_RS05680 99fbb96bf79045d15569e442f13f7932 419 PANTHER PTHR30193 179 419 6.7E-146 T 22-04-2016 TOLA_RS05680 99fbb96bf79045d15569e442f13f7932 419 PANTHER PTHR30193 7 75 6.7E-146 T 22-04-2016 TOLA_RS05680 99fbb96bf79045d15569e442f13f7932 419 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 220 410 7.6E-9 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05680 99fbb96bf79045d15569e442f13f7932 419 SUPERFAMILY SSF161098 195 407 1.06E-43 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05680 99fbb96bf79045d15569e442f13f7932 419 PANTHER PTHR30193:SF8 179 419 6.7E-146 T 22-04-2016 TOLA_RS05680 99fbb96bf79045d15569e442f13f7932 419 PANTHER PTHR30193:SF8 7 75 6.7E-146 T 22-04-2016 TOLA_RS05680 99fbb96bf79045d15569e442f13f7932 419 Gene3D G3DSA:1.10.3720.10 37 63 3.4E-47 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05680 99fbb96bf79045d15569e442f13f7932 419 Gene3D G3DSA:1.10.3720.10 183 413 3.4E-47 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09825 6140d76dde79e6463985904aff50a3a8 166 Pfam PF04126 Cyclophilin-like 51 152 2.8E-5 T 22-04-2016 IPR025658 Cyclophilin TM1367-like domain TOLA_RS09825 6140d76dde79e6463985904aff50a3a8 166 SUPERFAMILY SSF50891 51 164 5.69E-22 T 22-04-2016 IPR029000 Cyclophilin-like domain TOLA_RS15405 079b25b55d09065c393ae9f353d21454 679 SUPERFAMILY SSF55486 1 677 2.41E-212 T 22-04-2016 TOLA_RS15405 079b25b55d09065c393ae9f353d21454 679 Pfam PF01432 Peptidase family M3 222 677 1.6E-162 T 22-04-2016 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 TOLA_RS15405 079b25b55d09065c393ae9f353d21454 679 PANTHER PTHR11804:SF8 2 678 0.0 T 22-04-2016 TOLA_RS15405 079b25b55d09065c393ae9f353d21454 679 Gene3D G3DSA:1.10.1370.10 505 678 8.3E-141 T 22-04-2016 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 TOLA_RS15405 079b25b55d09065c393ae9f353d21454 679 Gene3D G3DSA:1.10.1370.10 140 349 8.3E-141 T 22-04-2016 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 TOLA_RS15405 079b25b55d09065c393ae9f353d21454 679 PANTHER PTHR11804 2 678 0.0 T 22-04-2016 TOLA_RS15405 079b25b55d09065c393ae9f353d21454 679 Gene3D G3DSA:3.40.390.10 360 504 2.3E-60 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 TOLA_RS15405 079b25b55d09065c393ae9f353d21454 679 Gene3D G3DSA:1.20.1050.40 10 138 2.0E-25 T 22-04-2016 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal TOLA_RS04745 d482ed0d417cf8ff4927dcf6f3e17a70 77 Hamap MF_00816 UPF0352 protein YejL [yejL]. 1 71 19.846 T 22-04-2016 IPR009857 Uncharacterised protein family UPF0352 TOLA_RS04745 d482ed0d417cf8ff4927dcf6f3e17a70 77 ProDom PD027794 UPF0352 YEJL NTHI1007 CPS_2611 VF1649 VV1166 HD1515 VP2129 YPO1261/Y2923/YP0880 ECA2748 1 69 2.0E-14 T 22-04-2016 IPR009857 Uncharacterised protein family UPF0352 TOLA_RS04745 d482ed0d417cf8ff4927dcf6f3e17a70 77 PIRSF PIRSF006188 1 72 1.2E-25 T 22-04-2016 IPR009857 Uncharacterised protein family UPF0352 TOLA_RS04745 d482ed0d417cf8ff4927dcf6f3e17a70 77 Pfam PF07208 Protein of unknown function (DUF1414) 26 69 6.7E-20 T 22-04-2016 IPR009857 Uncharacterised protein family UPF0352 TOLA_RS04745 d482ed0d417cf8ff4927dcf6f3e17a70 77 SUPERFAMILY SSF158651 1 73 2.22E-25 T 22-04-2016 TOLA_RS04745 d482ed0d417cf8ff4927dcf6f3e17a70 77 Gene3D G3DSA:1.10.3390.10 1 72 9.8E-29 T 22-04-2016 IPR023202 YejL-like domain TOLA_RS08090 cb92c24273ac6364c22638d734145682 543 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 47 227 4.3E-8 T 22-04-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 TOLA_RS08090 cb92c24273ac6364c22638d734145682 543 Gene3D G3DSA:3.40.50.620 41 231 5.4E-22 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS08090 cb92c24273ac6364c22638d734145682 543 PANTHER PTHR23293 287 351 3.4E-21 T 22-04-2016 TOLA_RS08090 cb92c24273ac6364c22638d734145682 543 PANTHER PTHR23293 45 226 3.4E-21 T 22-04-2016 TOLA_RS08090 cb92c24273ac6364c22638d734145682 543 PANTHER PTHR23293 257 268 3.4E-21 T 22-04-2016 TOLA_RS08090 cb92c24273ac6364c22638d734145682 543 PANTHER PTHR23293:SF6 287 351 3.4E-21 T 22-04-2016 TOLA_RS08090 cb92c24273ac6364c22638d734145682 543 PANTHER PTHR23293:SF6 45 226 3.4E-21 T 22-04-2016 TOLA_RS08090 cb92c24273ac6364c22638d734145682 543 PANTHER PTHR23293:SF6 257 268 3.4E-21 T 22-04-2016 TOLA_RS08090 cb92c24273ac6364c22638d734145682 543 SUPERFAMILY SSF52402 37 230 1.41E-20 T 22-04-2016 TOLA_RS12110 f2795414f117ce9856edddcf512555b1 296 PIRSF PIRSF005651 1 296 1.2E-97 T 22-04-2016 IPR010200 HflC GO:0016021|GO:0052547 TOLA_RS12110 f2795414f117ce9856edddcf512555b1 296 PANTHER PTHR10264:SF80 5 290 6.6E-101 T 22-04-2016 TOLA_RS12110 f2795414f117ce9856edddcf512555b1 296 SUPERFAMILY SSF117892 57 193 1.44E-26 T 22-04-2016 IPR001107 Band 7 domain TOLA_RS12110 f2795414f117ce9856edddcf512555b1 296 TIGRFAM TIGR01932 hflC: HflC protein 158 288 3.0E-52 T 22-04-2016 IPR010200 HflC GO:0016021|GO:0052547 TOLA_RS12110 f2795414f117ce9856edddcf512555b1 296 TIGRFAM TIGR01932 hflC: HflC protein 1 151 2.2E-53 T 22-04-2016 IPR010200 HflC GO:0016021|GO:0052547 TOLA_RS12110 f2795414f117ce9856edddcf512555b1 296 SMART SM00244 18 188 2.0E-43 T 22-04-2016 IPR001107 Band 7 domain TOLA_RS12110 f2795414f117ce9856edddcf512555b1 296 PANTHER PTHR10264 5 290 6.6E-101 T 22-04-2016 IPR001972 Stomatin family GO:0016020 TOLA_RS12110 f2795414f117ce9856edddcf512555b1 296 Pfam PF01145 SPFH domain / Band 7 family 22 203 8.6E-32 T 22-04-2016 IPR001107 Band 7 domain TOLA_RS07570 5a84b85b0e31d7784373a9434038efbe 255 Gene3D G3DSA:3.40.50.300 3 230 5.1E-60 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07570 5a84b85b0e31d7784373a9434038efbe 255 Pfam PF00005 ABC transporter 18 165 3.0E-30 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS07570 5a84b85b0e31d7784373a9434038efbe 255 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS07570 5a84b85b0e31d7784373a9434038efbe 255 SUPERFAMILY SSF52540 2 228 9.71E-58 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS07570 5a84b85b0e31d7784373a9434038efbe 255 SMART SM00382 26 214 1.2E-12 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS07570 5a84b85b0e31d7784373a9434038efbe 255 PANTHER PTHR24220:SF266 3 243 5.4E-106 T 22-04-2016 TOLA_RS07570 5a84b85b0e31d7784373a9434038efbe 255 PANTHER PTHR24220 3 243 5.4E-106 T 22-04-2016 TOLA_RS14820 217f8c7d46940e444e8245a8be5368f2 242 Pfam PF13795 HupE / UreJ protein 58 209 2.0E-52 T 22-04-2016 IPR032809 Putative HupE/UreJ protein TOLA_RS01165 6b4b12c988576ba1e48cbfee4aadcbb2 211 Gene3D G3DSA:3.20.20.70 2 208 2.6E-65 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS01165 6b4b12c988576ba1e48cbfee4aadcbb2 211 Pfam PF02581 Thiamine monophosphate synthase/TENI 7 189 2.2E-57 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01165 6b4b12c988576ba1e48cbfee4aadcbb2 211 SUPERFAMILY SSF51391 3 206 1.44E-60 T 22-04-2016 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01165 6b4b12c988576ba1e48cbfee4aadcbb2 211 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 5 207 25.707 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01165 6b4b12c988576ba1e48cbfee4aadcbb2 211 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 6 201 2.2E-58 T 22-04-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 TOLA_RS01165 6b4b12c988576ba1e48cbfee4aadcbb2 211 PANTHER PTHR20857:SF15 1 211 8.0E-62 T 22-04-2016 TOLA_RS01165 6b4b12c988576ba1e48cbfee4aadcbb2 211 PANTHER PTHR20857 1 211 8.0E-62 T 22-04-2016 TOLA_RS02275 fa2a0e05f1c954d9b4c02abb6118136e 206 Pfam PF01810 LysE type translocator 15 201 1.7E-31 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS02275 fa2a0e05f1c954d9b4c02abb6118136e 206 PIRSF PIRSF006324 1 206 1.1E-51 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS02275 fa2a0e05f1c954d9b4c02abb6118136e 206 PANTHER PTHR30086 1 201 2.2E-79 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS02275 fa2a0e05f1c954d9b4c02abb6118136e 206 PANTHER PTHR30086:SF14 1 201 2.2E-79 T 22-04-2016 TOLA_RS11920 e7de3f59ed23aa654535a07efcbde974 460 ProSitePatterns PS00218 Amino acid permeases signature. 42 72 - T 22-04-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 TOLA_RS11920 e7de3f59ed23aa654535a07efcbde974 460 PANTHER PTHR11785 6 444 1.6E-274 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 TOLA_RS11920 e7de3f59ed23aa654535a07efcbde974 460 Gene3D G3DSA:3.40.50.1820 37 72 7.7E-4 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS11920 e7de3f59ed23aa654535a07efcbde974 460 PANTHER PTHR11785:SF26 6 444 1.6E-274 T 22-04-2016 TOLA_RS11920 e7de3f59ed23aa654535a07efcbde974 460 Pfam PF00324 Amino acid permease 17 418 4.2E-115 T 22-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 TOLA_RS11920 e7de3f59ed23aa654535a07efcbde974 460 PIRSF PIRSF006060 1 448 1.2E-72 T 22-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 TOLA_RS09080 3a3fb4072d0cb18bae3236e9a1642ae1 116 SUPERFAMILY SSF54427 2 114 1.05E-22 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS09080 3a3fb4072d0cb18bae3236e9a1642ae1 116 Pfam PF13577 SnoaL-like domain 3 113 2.4E-19 T 22-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain TOLA_RS09080 3a3fb4072d0cb18bae3236e9a1642ae1 116 Gene3D G3DSA:3.10.450.50 2 115 5.1E-22 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS09670 e6ad9d1510ab2263754ba16f7f859125 106 PANTHER PTHR30505:SF0 3 98 7.6E-40 T 22-04-2016 TOLA_RS09670 e6ad9d1510ab2263754ba16f7f859125 106 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 5 89 3.1E-39 T 22-04-2016 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 TOLA_RS09670 e6ad9d1510ab2263754ba16f7f859125 106 SUPERFAMILY SSF52794 3 101 6.63E-35 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS09670 e6ad9d1510ab2263754ba16f7f859125 106 PANTHER PTHR30505 3 98 7.6E-40 T 22-04-2016 TOLA_RS09670 e6ad9d1510ab2263754ba16f7f859125 106 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 6 94 2.6E-20 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS09670 e6ad9d1510ab2263754ba16f7f859125 106 Gene3D G3DSA:3.40.50.2300 2 101 1.6E-40 T 22-04-2016 TOLA_RS13395 259e8455f0636f36f0cfb6e499252558 326 Gene3D G3DSA:2.70.98.10 3 323 4.2E-100 T 22-04-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 TOLA_RS13395 259e8455f0636f36f0cfb6e499252558 326 Pfam PF01263 Aldose 1-epimerase 4 322 3.7E-73 T 22-04-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 TOLA_RS13395 259e8455f0636f36f0cfb6e499252558 326 PANTHER PTHR10091:SF0 3 326 6.3E-117 T 22-04-2016 TOLA_RS13395 259e8455f0636f36f0cfb6e499252558 326 PANTHER PTHR10091 3 326 6.3E-117 T 22-04-2016 TOLA_RS13395 259e8455f0636f36f0cfb6e499252558 326 PIRSF PIRSF005096 1 326 4.9E-102 T 22-04-2016 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317|UniPathway: UPA00242 TOLA_RS13395 259e8455f0636f36f0cfb6e499252558 326 SUPERFAMILY SSF74650 3 323 1.63E-92 T 22-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 TOLA_RS07200 23af86af8ea5135532eaab73857263b5 395 Pfam PF07238 PilZ domain 15 114 1.6E-4 T 22-04-2016 IPR009875 PilZ domain GO:0035438 TOLA_RS07200 23af86af8ea5135532eaab73857263b5 395 Gene3D G3DSA:2.40.10.220 12 119 2.1E-5 T 22-04-2016 TOLA_RS07200 23af86af8ea5135532eaab73857263b5 395 SUPERFAMILY SSF141371 9 129 5.3E-7 T 22-04-2016 TOLA_RS07200 23af86af8ea5135532eaab73857263b5 395 Gene3D G3DSA:2.40.50.100 209 293 9.3E-4 T 22-04-2016 TOLA_RS07200 23af86af8ea5135532eaab73857263b5 395 Pfam PF13437 HlyD family secretion protein 261 358 1.4E-4 T 22-04-2016 TOLA_RS02160 64938612810de2409776315073ecb7d5 299 PANTHER PTHR30389:SF3 4 297 1.0E-167 T 22-04-2016 TOLA_RS02160 64938612810de2409776315073ecb7d5 299 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 11 282 8.7E-97 T 22-04-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 TOLA_RS02160 64938612810de2409776315073ecb7d5 299 PANTHER PTHR30389 4 297 1.0E-167 T 22-04-2016 TOLA_RS02160 64938612810de2409776315073ecb7d5 299 Pfam PF05681 Fumarate hydratase (Fumerase) 14 281 2.5E-75 T 22-04-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 TOLA_RS14620 f489b1eca26736f64f50a3a4fe02a725 134 SUPERFAMILY SSF47413 34 98 5.91E-12 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS14620 f489b1eca26736f64f50a3a4fe02a725 134 SMART SM00530 34 89 1.1E-5 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS14620 f489b1eca26736f64f50a3a4fe02a725 134 Pfam PF01381 Helix-turn-helix 39 86 4.0E-8 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS14620 f489b1eca26736f64f50a3a4fe02a725 134 Gene3D G3DSA:1.10.260.40 40 88 2.4E-10 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS03300 9005eb5ed79679704f1510ef029dfe11 196 PANTHER PTHR41729 3 196 2.3E-66 T 22-04-2016 TOLA_RS03300 9005eb5ed79679704f1510ef029dfe11 196 PANTHER PTHR41729:SF1 3 196 2.3E-66 T 22-04-2016 TOLA_RS03300 9005eb5ed79679704f1510ef029dfe11 196 Pfam PF13875 Domain of unknown function (DUF4202) 9 191 3.3E-74 T 22-04-2016 IPR025255 Protein of unknown function DUF4202 TOLA_RS09465 c141a3eb4b6ffe577d632f02303613bf 290 PANTHER PTHR31527 1 281 7.3E-91 T 22-04-2016 TOLA_RS09465 c141a3eb4b6ffe577d632f02303613bf 290 Pfam PF09347 Domain of unknown function (DUF1989) 41 215 1.2E-64 T 22-04-2016 IPR018959 Domain of unknown function DUF1989 TOLA_RS09465 c141a3eb4b6ffe577d632f02303613bf 290 PANTHER PTHR31527:SF0 1 281 7.3E-91 T 22-04-2016 TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 Gene3D G3DSA:1.20.1250.20 261 473 6.2E-19 T 22-04-2016 TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 PANTHER PTHR23501:SF1 4 468 1.2E-211 T 22-04-2016 TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 SUPERFAMILY SSF103473 247 468 3.27E-66 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 SUPERFAMILY SSF103473 9 197 3.27E-66 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 108 128 3.4E-8 T 22-04-2016 TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 3.4E-8 T 22-04-2016 TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 3.4E-8 T 22-04-2016 TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 3.4E-8 T 22-04-2016 TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 PRINTS PR01036 Tetracycline resistance protein TetB signature 202 220 3.4E-8 T 22-04-2016 TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 417 2.4E-79 T 22-04-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 Gene3D G3DSA:1.20.1250.20 16 196 1.0E-32 T 22-04-2016 TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 Pfam PF07690 Major Facilitator Superfamily 19 408 5.8E-51 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS00910 e2f075bba49ab3a7c97ae59b03378652 482 PANTHER PTHR23501 4 468 1.2E-211 T 22-04-2016 TOLA_RS10050 68dcd308531c7813a61a4d038bc5be80 530 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 463 480 - T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS10050 68dcd308531c7813a61a4d038bc5be80 530 Pfam PF02378 Phosphotransferase system, EIIC 14 355 9.1E-88 T 22-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 TOLA_RS10050 68dcd308531c7813a61a4d038bc5be80 530 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 417 509 2.0E-21 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS10050 68dcd308531c7813a61a4d038bc5be80 530 Pfam PF00367 phosphotransferase system, EIIB 453 485 1.5E-12 T 22-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 TOLA_RS10050 68dcd308531c7813a61a4d038bc5be80 530 Gene3D G3DSA:3.30.1360.60 447 524 3.3E-27 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS10050 68dcd308531c7813a61a4d038bc5be80 530 SUPERFAMILY SSF55604 451 524 8.11E-22 T 22-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 TOLA_RS10050 68dcd308531c7813a61a4d038bc5be80 530 PANTHER PTHR30009:SF2 6 524 1.9E-173 T 22-04-2016 TOLA_RS10050 68dcd308531c7813a61a4d038bc5be80 530 PANTHER PTHR30009 6 524 1.9E-173 T 22-04-2016 TOLA_RS04085 4f47e5c61429fe7ea423d03970f221a6 190 Pfam PF03923 Uncharacterized lipoprotein 43 187 1.1E-23 T 22-04-2016 IPR005619 Uncharacterised protein family, YajG TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 SMART SM00465 17 98 2.0E-23 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 SUPERFAMILY SSF46600 190 243 5.49E-13 T 22-04-2016 IPR001943 UVR domain GO:0005515 TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 Gene3D G3DSA:1.10.150.20 557 610 3.6E-20 T 22-04-2016 TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 385 543 9.7E-47 T 22-04-2016 IPR001162 UvrC family homology region TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 Pfam PF01541 GIY-YIG catalytic domain 18 93 2.0E-12 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 Pfam PF02151 UvrB/uvrC motif 205 238 4.7E-9 T 22-04-2016 IPR001943 UVR domain GO:0005515 TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 SMART SM00278 589 608 0.18 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 SMART SM00278 557 576 0.26 T 22-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 Gene3D G3DSA:3.40.1440.10 17 97 1.3E-10 T 22-04-2016 IPR027299 GIY-YIG domain TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 PANTHER PTHR30562:SF1 7 609 3.5E-277 T 22-04-2016 TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 10 589 8.9E-204 T 22-04-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 Pfam PF14520 Helix-hairpin-helix domain 558 608 1.4E-8 T 22-04-2016 TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 SUPERFAMILY SSF82771 17 100 9.42E-24 T 22-04-2016 IPR000305 GIY-YIG nuclease superfamily TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 608 28.738 T 22-04-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 Gene3D G3DSA:4.10.860.10 183 243 1.0E-17 T 22-04-2016 IPR001943 UVR domain GO:0005515 TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 SUPERFAMILY SSF47781 522 610 1.18E-21 T 22-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 TOLA_RS07880 2e1e5e8f00c14e538aa022f703f1807a 610 PANTHER PTHR30562 7 609 3.5E-277 T 22-04-2016 TOLA_RS06600 038ac2e65ebe42a377054edadf42af01 136 Pfam PF00472 RF-1 domain 7 132 8.5E-26 T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TOLA_RS06600 038ac2e65ebe42a377054edadf42af01 136 Gene3D G3DSA:3.30.160.200 3 107 6.7E-34 T 22-04-2016 TOLA_RS06600 038ac2e65ebe42a377054edadf42af01 136 SUPERFAMILY SSF75620 6 114 1.1E-11 T 22-04-2016 TOLA_RS06600 038ac2e65ebe42a377054edadf42af01 136 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 22-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TOLA_RS06600 038ac2e65ebe42a377054edadf42af01 136 PANTHER PTHR11075 5 135 4.6E-41 T 22-04-2016 TOLA_RS15020 c52efedba8ae188b9feb029f13cd0356 86 Gene3D G3DSA:3.30.750.24 2 83 6.1E-13 T 22-04-2016 IPR002645 STAS domain TOLA_RS15020 c52efedba8ae188b9feb029f13cd0356 86 PANTHER PTHR35849:SF1 1 81 3.0E-14 T 22-04-2016 TOLA_RS15020 c52efedba8ae188b9feb029f13cd0356 86 Pfam PF13466 STAS domain 1 77 8.8E-17 T 22-04-2016 IPR002645 STAS domain TOLA_RS15020 c52efedba8ae188b9feb029f13cd0356 86 PANTHER PTHR35849 1 81 3.0E-14 T 22-04-2016 TOLA_RS15020 c52efedba8ae188b9feb029f13cd0356 86 SUPERFAMILY SSF52091 2 84 2.55E-14 T 22-04-2016 IPR002645 STAS domain TOLA_RS10520 4afdea32a4c590f0b1f503af7f09608d 411 SUPERFAMILY SSF56300 2 348 1.29E-47 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS10520 4afdea32a4c590f0b1f503af7f09608d 411 Gene3D G3DSA:3.60.21.10 2 281 2.4E-54 T 22-04-2016 IPR029052 Metallo-dependent phosphatase-like TOLA_RS10520 4afdea32a4c590f0b1f503af7f09608d 411 Pfam PF00149 Calcineurin-like phosphoesterase 2 233 3.5E-15 T 22-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 TOLA_RS10520 4afdea32a4c590f0b1f503af7f09608d 411 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 285 387 1.5E-12 T 22-04-2016 IPR026843 Nuclease SbcCD subunit D, C-terminal domain TOLA_RS10520 4afdea32a4c590f0b1f503af7f09608d 411 PANTHER PTHR30337 1 354 2.0E-66 T 22-04-2016 TOLA_RS10520 4afdea32a4c590f0b1f503af7f09608d 411 PANTHER PTHR30337:SF0 1 354 2.0E-66 T 22-04-2016 TOLA_RS10520 4afdea32a4c590f0b1f503af7f09608d 411 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 2 258 3.6E-55 T 22-04-2016 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 TOLA_RS08875 3bee918bc3f55f9653d6646b90915548 396 SUPERFAMILY SSF111369 57 142 9.42E-9 T 22-04-2016 TOLA_RS08875 3bee918bc3f55f9653d6646b90915548 396 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 287 8.9E-19 T 22-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TOLA_RS08875 3bee918bc3f55f9653d6646b90915548 396 PANTHER PTHR30386 14 373 1.1E-157 T 22-04-2016 TOLA_RS08875 3bee918bc3f55f9653d6646b90915548 396 PANTHER PTHR30386:SF6 14 373 1.1E-157 T 22-04-2016 TOLA_RS08875 3bee918bc3f55f9653d6646b90915548 396 SUPERFAMILY SSF111369 158 266 4.58E-8 T 22-04-2016 TOLA_RS08875 3bee918bc3f55f9653d6646b90915548 396 Pfam PF00529 HlyD membrane-fusion protein of T1SS 106 342 9.3E-10 T 22-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 TOLA_RS08875 3bee918bc3f55f9653d6646b90915548 396 Gene3D G3DSA:2.40.50.100 212 245 3.9E-16 T 22-04-2016 TOLA_RS08875 3bee918bc3f55f9653d6646b90915548 396 Gene3D G3DSA:2.40.50.100 59 91 3.9E-16 T 22-04-2016 TOLA_RS12760 9e8c878c60eac1e4acd120db57f3aad7 141 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 116 1.1E-43 T 22-04-2016 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 TOLA_RS12760 9e8c878c60eac1e4acd120db57f3aad7 141 Pfam PF03960 ArsC family 7 114 3.2E-17 T 22-04-2016 IPR006660 Arsenate reductase-like TOLA_RS12760 9e8c878c60eac1e4acd120db57f3aad7 141 PANTHER PTHR30041 1 136 4.6E-52 T 22-04-2016 TOLA_RS12760 9e8c878c60eac1e4acd120db57f3aad7 141 SUPERFAMILY SSF52833 4 138 1.6E-39 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS12760 9e8c878c60eac1e4acd120db57f3aad7 141 PANTHER PTHR30041:SF0 1 136 4.6E-52 T 22-04-2016 TOLA_RS12760 9e8c878c60eac1e4acd120db57f3aad7 141 Gene3D G3DSA:3.40.30.10 1 140 1.9E-61 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS09400 53a343fd4c7f241fd15eede5fcdac7b3 368 Gene3D G3DSA:3.60.15.10 69 362 2.2E-93 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS09400 53a343fd4c7f241fd15eede5fcdac7b3 368 SUPERFAMILY SSF56281 204 349 8.39E-35 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS09400 53a343fd4c7f241fd15eede5fcdac7b3 368 SUPERFAMILY SSF56281 102 177 8.39E-35 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS09400 53a343fd4c7f241fd15eede5fcdac7b3 368 Pfam PF12706 Beta-lactamase superfamily domain 120 311 1.4E-37 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS09400 53a343fd4c7f241fd15eede5fcdac7b3 368 PANTHER PTHR15032:SF4 18 361 1.6E-80 T 22-04-2016 TOLA_RS09400 53a343fd4c7f241fd15eede5fcdac7b3 368 PANTHER PTHR15032 18 361 1.6E-80 T 22-04-2016 TOLA_RS05045 f2fd5552888e0bc04a83b292ef2d8e0d 140 Gene3D G3DSA:1.10.10.10 9 133 8.2E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05045 f2fd5552888e0bc04a83b292ef2d8e0d 140 Pfam PF12802 MarR family 32 92 2.6E-13 T 22-04-2016 TOLA_RS05045 f2fd5552888e0bc04a83b292ef2d8e0d 140 PANTHER PTHR33164 8 134 3.3E-17 T 22-04-2016 TOLA_RS05045 f2fd5552888e0bc04a83b292ef2d8e0d 140 SUPERFAMILY SSF46785 8 133 3.0E-25 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05045 f2fd5552888e0bc04a83b292ef2d8e0d 140 SMART SM00347 26 129 8.2E-13 T 22-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TOLA_RS10905 959977d8b6eff554287f8cbacb3b0052 75 PANTHER PTHR33238 1 72 9.7E-16 T 22-04-2016 TOLA_RS10905 959977d8b6eff554287f8cbacb3b0052 75 Pfam PF04023 FeoA domain 1 73 6.8E-16 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TOLA_RS10905 959977d8b6eff554287f8cbacb3b0052 75 SUPERFAMILY SSF50037 4 73 9.61E-17 T 22-04-2016 IPR008988 Transcriptional repressor, C-terminal TOLA_RS10905 959977d8b6eff554287f8cbacb3b0052 75 SMART SM00899 1 74 1.7E-18 T 22-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TOLA_RS07485 fa6e5afdaf0c663d026bc1d3a7a8005f 360 Pfam PF02608 Basic membrane protein 31 311 1.9E-48 T 22-04-2016 IPR003760 Basic membrane lipoprotein GO:0005886 TOLA_RS07485 fa6e5afdaf0c663d026bc1d3a7a8005f 360 PANTHER PTHR34296 8 351 7.4E-140 T 22-04-2016 TOLA_RS07485 fa6e5afdaf0c663d026bc1d3a7a8005f 360 Gene3D G3DSA:3.40.50.2300 27 166 1.6E-44 T 22-04-2016 TOLA_RS07485 fa6e5afdaf0c663d026bc1d3a7a8005f 360 Gene3D G3DSA:3.40.50.2300 180 228 4.7E-4 T 22-04-2016 TOLA_RS07485 fa6e5afdaf0c663d026bc1d3a7a8005f 360 PANTHER PTHR34296:SF1 8 351 7.4E-140 T 22-04-2016 TOLA_RS07485 fa6e5afdaf0c663d026bc1d3a7a8005f 360 SUPERFAMILY SSF53822 180 229 1.39E-5 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS10285 2da41a10ceb5931acc146ec8128b04df 331 PANTHER PTHR30217:SF3 240 330 5.3E-209 T 22-04-2016 TOLA_RS10285 2da41a10ceb5931acc146ec8128b04df 331 PANTHER PTHR30217:SF3 1 218 5.3E-209 T 22-04-2016 TOLA_RS10285 2da41a10ceb5931acc146ec8128b04df 331 PANTHER PTHR30217 240 330 5.3E-209 T 22-04-2016 TOLA_RS10285 2da41a10ceb5931acc146ec8128b04df 331 PANTHER PTHR30217 1 218 5.3E-209 T 22-04-2016 TOLA_RS10285 2da41a10ceb5931acc146ec8128b04df 331 Pfam PF01136 Peptidase family U32 76 330 4.1E-70 T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS10285 2da41a10ceb5931acc146ec8128b04df 331 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS05990 b1e1d6dc757b1cbaf50386f9ab817c1a 78 SUPERFAMILY SSF46955 18 73 2.93E-5 T 22-04-2016 IPR009061 Putative DNA-binding domain TOLA_RS08435 25d753e1c7c109da604778f02832c58e 286 SMART SM00849 23 249 5.2E-5 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS08435 25d753e1c7c109da604778f02832c58e 286 SUPERFAMILY SSF56281 3 105 1.27E-35 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS08435 25d753e1c7c109da604778f02832c58e 286 SUPERFAMILY SSF56281 139 265 1.27E-35 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS08435 25d753e1c7c109da604778f02832c58e 286 PANTHER PTHR13754 4 277 4.2E-62 T 22-04-2016 TOLA_RS08435 25d753e1c7c109da604778f02832c58e 286 PANTHER PTHR13754:SF13 4 277 4.2E-62 T 22-04-2016 TOLA_RS08435 25d753e1c7c109da604778f02832c58e 286 Pfam PF00753 Metallo-beta-lactamase superfamily 24 90 9.9E-13 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS08435 25d753e1c7c109da604778f02832c58e 286 Gene3D G3DSA:3.60.15.10 6 270 4.6E-34 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS06030 e9fd67ef8f40354e93aff5d4aa815305 805 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 75 444 2.3E-76 T 22-04-2016 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 TOLA_RS06030 e9fd67ef8f40354e93aff5d4aa815305 805 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 295 319 5.9E-21 T 22-04-2016 TOLA_RS06030 e9fd67ef8f40354e93aff5d4aa815305 805 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 158 174 5.9E-21 T 22-04-2016 TOLA_RS06030 e9fd67ef8f40354e93aff5d4aa815305 805 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 258 270 5.9E-21 T 22-04-2016 TOLA_RS06030 e9fd67ef8f40354e93aff5d4aa815305 805 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 186 200 5.9E-21 T 22-04-2016 TOLA_RS06030 e9fd67ef8f40354e93aff5d4aa815305 805 PANTHER PTHR30408 136 453 7.4E-97 T 22-04-2016 TOLA_RS06030 e9fd67ef8f40354e93aff5d4aa815305 805 Pfam PF02384 N-6 DNA Methylase 135 443 1.1E-103 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TOLA_RS06030 e9fd67ef8f40354e93aff5d4aa815305 805 Gene3D G3DSA:3.40.50.150 160 391 9.2E-36 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS06030 e9fd67ef8f40354e93aff5d4aa815305 805 PANTHER PTHR30408:SF4 136 453 7.4E-97 T 22-04-2016 TOLA_RS06030 e9fd67ef8f40354e93aff5d4aa815305 805 SUPERFAMILY SSF53335 7 487 4.37E-128 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS06030 e9fd67ef8f40354e93aff5d4aa815305 805 Pfam PF12161 HsdM N-terminal domain 8 121 2.4E-17 T 22-04-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain TOLA_RS06030 e9fd67ef8f40354e93aff5d4aa815305 805 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 261 267 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TOLA_RS05215 7b62054af4e9eadb84c2a2e234b50405 291 PANTHER PTHR30193 1 291 5.8E-96 T 22-04-2016 TOLA_RS05215 7b62054af4e9eadb84c2a2e234b50405 291 Gene3D G3DSA:1.10.3720.10 60 289 4.8E-61 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05215 7b62054af4e9eadb84c2a2e234b50405 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 287 8.9E-19 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05215 7b62054af4e9eadb84c2a2e234b50405 291 SUPERFAMILY SSF161098 54 282 5.1E-61 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS05215 7b62054af4e9eadb84c2a2e234b50405 291 PANTHER PTHR30193:SF6 1 291 5.8E-96 T 22-04-2016 TOLA_RS05215 7b62054af4e9eadb84c2a2e234b50405 291 Gene3D G3DSA:1.20.58.370 12 39 2.2E-4 T 22-04-2016 TOLA_RS15265 9c91d9622820a845eb43736890c86a38 88 Pfam PF06288 Protein of unknown function (DUF1040) 1 86 4.5E-42 T 22-04-2016 IPR009383 Protein of unknown function DUF1040 TOLA_RS15265 9c91d9622820a845eb43736890c86a38 88 ProDom PD029038 YIHD CYTOPLASMIC ENZYME Y3814 GLYCOGEN YPO0013A HI0845 DIRECT ORF1 UNCHARACTERIZED 1 87 8.0E-19 T 22-04-2016 IPR009383 Protein of unknown function DUF1040 TOLA_RS03290 8e0b64611b9f9256192b7f1178e16e29 436 Pfam PF06097 Bacterial protein of unknown function (DUF945) 15 435 1.1E-12 T 22-04-2016 IPR010352 Protein of unknown function DUF945 TOLA_RS12595 14932b2edf0b415b4be0998e2451895c 164 PRINTS PR01438 Universal stress protein signature 124 146 1.56E-17 T 22-04-2016 IPR006015 Universal stress protein A TOLA_RS12595 14932b2edf0b415b4be0998e2451895c 164 PRINTS PR01438 Universal stress protein signature 2 20 1.56E-17 T 22-04-2016 IPR006015 Universal stress protein A TOLA_RS12595 14932b2edf0b415b4be0998e2451895c 164 PRINTS PR01438 Universal stress protein signature 106 118 1.56E-17 T 22-04-2016 IPR006015 Universal stress protein A TOLA_RS12595 14932b2edf0b415b4be0998e2451895c 164 PANTHER PTHR31964 1 152 3.8E-26 T 22-04-2016 TOLA_RS12595 14932b2edf0b415b4be0998e2451895c 164 Pfam PF00582 Universal stress protein family 1 146 1.4E-26 T 22-04-2016 IPR006016 UspA GO:0006950 TOLA_RS12595 14932b2edf0b415b4be0998e2451895c 164 Gene3D G3DSA:3.40.50.620 1 149 1.3E-33 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS12595 14932b2edf0b415b4be0998e2451895c 164 SUPERFAMILY SSF52402 1 148 5.86E-33 T 22-04-2016 TOLA_RS05845 a428cae7a225d973fbf7d6c73018deb1 326 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 15 168 1.5E-41 T 22-04-2016 IPR017482 Putative phage-type endonuclease TOLA_RS05845 a428cae7a225d973fbf7d6c73018deb1 326 Pfam PF09588 YqaJ-like viral recombinase domain 22 157 7.0E-34 T 22-04-2016 IPR019080 YqaJ viral recombinase TOLA_RS05845 a428cae7a225d973fbf7d6c73018deb1 326 Gene3D G3DSA:3.90.320.10 17 199 6.0E-34 T 22-04-2016 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 TOLA_RS05845 a428cae7a225d973fbf7d6c73018deb1 326 SUPERFAMILY SSF52980 17 200 3.22E-37 T 22-04-2016 IPR011335 Restriction endonuclease type II-like TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 PANTHER PTHR10799 472 734 1.6E-19 T 22-04-2016 TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 PANTHER PTHR10799 221 254 1.6E-19 T 22-04-2016 TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 PANTHER PTHR10799 68 174 1.6E-19 T 22-04-2016 TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 PANTHER PTHR10799 347 424 1.6E-19 T 22-04-2016 TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 SUPERFAMILY SSF52540 349 411 1.05E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 SUPERFAMILY SSF52540 72 162 1.05E-20 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 Pfam PF00271 Helicase conserved C-terminal domain 587 697 5.8E-7 T 22-04-2016 IPR001650 Helicase, C-terminal TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 PANTHER PTHR10799:SF756 472 734 1.6E-19 T 22-04-2016 TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 PANTHER PTHR10799:SF756 221 254 1.6E-19 T 22-04-2016 TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 PANTHER PTHR10799:SF756 68 174 1.6E-19 T 22-04-2016 TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 PANTHER PTHR10799:SF756 347 424 1.6E-19 T 22-04-2016 TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 SMART SM00487 72 430 1.7E-6 T 22-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 Gene3D G3DSA:3.40.50.300 582 706 6.1E-12 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 Gene3D G3DSA:3.40.50.300 348 406 8.2E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 Gene3D G3DSA:3.40.50.300 66 190 8.2E-22 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 SUPERFAMILY SSF52540 573 738 5.08E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12335 27cccd592b5e1387714e2d94b89515a6 761 SUPERFAMILY SSF52540 353 410 5.08E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03120 dd51076c759c54f742f010393e1efe7a 68 Pfam PF13187 4Fe-4S dicluster domain 8 58 2.2E-6 T 22-04-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TOLA_RS03120 dd51076c759c54f742f010393e1efe7a 68 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 22-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TOLA_RS03120 dd51076c759c54f742f010393e1efe7a 68 Gene3D G3DSA:3.30.70.20 5 65 6.9E-15 T 22-04-2016 TOLA_RS03120 dd51076c759c54f742f010393e1efe7a 68 SUPERFAMILY SSF54862 6 64 3.76E-14 T 22-04-2016 TOLA_RS05750 7e69f1da726ba92091ae90b542df5c7e 149 PANTHER PTHR30574 2 135 1.2E-29 T 22-04-2016 TOLA_RS05750 7e69f1da726ba92091ae90b542df5c7e 149 PANTHER PTHR30574:SF1 2 135 1.2E-29 T 22-04-2016 TOLA_RS11545 61aea3c7eb983bd90e590cf9ba094a28 797 PANTHER PTHR30195:SF10 10 787 4.3E-301 T 22-04-2016 TOLA_RS11545 61aea3c7eb983bd90e590cf9ba094a28 797 SUPERFAMILY SSF53335 80 543 1.74E-116 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS11545 61aea3c7eb983bd90e590cf9ba094a28 797 SUPERFAMILY SSF53335 7 47 1.74E-116 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS11545 61aea3c7eb983bd90e590cf9ba094a28 797 Pfam PF12161 HsdM N-terminal domain 9 149 5.2E-22 T 22-04-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain TOLA_RS11545 61aea3c7eb983bd90e590cf9ba094a28 797 Pfam PF02384 N-6 DNA Methylase 177 491 9.7E-62 T 22-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TOLA_RS11545 61aea3c7eb983bd90e590cf9ba094a28 797 Gene3D G3DSA:3.40.50.150 199 469 1.4E-32 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS11545 61aea3c7eb983bd90e590cf9ba094a28 797 PANTHER PTHR30195 10 787 4.3E-301 T 22-04-2016 TOLA_RS11545 61aea3c7eb983bd90e590cf9ba094a28 797 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 303 315 4.7E-13 T 22-04-2016 TOLA_RS11545 61aea3c7eb983bd90e590cf9ba094a28 797 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 227 241 4.7E-13 T 22-04-2016 TOLA_RS11545 61aea3c7eb983bd90e590cf9ba094a28 797 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 197 213 4.7E-13 T 22-04-2016 TOLA_RS11545 61aea3c7eb983bd90e590cf9ba094a28 797 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 306 312 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TOLA_RS00955 931c1b22d61d4e31942a85aefe366346 94 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 3.4E-28 T 22-04-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS00955 931c1b22d61d4e31942a85aefe366346 94 SMART SM01409 8 61 7.0E-16 T 22-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS00955 931c1b22d61d4e31942a85aefe366346 94 Gene3D G3DSA:3.90.940.10 1 77 1.6E-16 T 22-04-2016 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS00955 931c1b22d61d4e31942a85aefe366346 94 Pfam PF01192 RNA polymerase Rpb6 10 59 3.8E-17 T 22-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS00955 931c1b22d61d4e31942a85aefe366346 94 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 17.338 T 22-04-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS00955 931c1b22d61d4e31942a85aefe366346 94 SUPERFAMILY SSF63562 1 77 3.14E-25 T 22-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TOLA_RS00955 931c1b22d61d4e31942a85aefe366346 94 PANTHER PTHR34476 2 91 8.7E-30 T 22-04-2016 TOLA_RS07020 e9611bba2557020249e6664e11bf287f 321 PANTHER PTHR32196:SF40 6 321 1.2E-97 T 22-04-2016 TOLA_RS07020 e9611bba2557020249e6664e11bf287f 321 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 297 2.5E-35 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS07020 e9611bba2557020249e6664e11bf287f 321 PANTHER PTHR32196 6 321 1.2E-97 T 22-04-2016 TOLA_RS01345 62ad528666e854976e5cf09636ccff18 291 PANTHER PTHR34138:SF1 1 276 2.0E-77 T 22-04-2016 TOLA_RS01345 62ad528666e854976e5cf09636ccff18 291 Pfam PF04085 rod shape-determining protein MreC 124 269 2.5E-38 T 22-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 TOLA_RS01345 62ad528666e854976e5cf09636ccff18 291 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 2 274 2.3E-82 T 22-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 TOLA_RS01345 62ad528666e854976e5cf09636ccff18 291 PIRSF PIRSF038471 2 279 9.3E-78 T 22-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 TOLA_RS01345 62ad528666e854976e5cf09636ccff18 291 PANTHER PTHR34138 1 276 2.0E-77 T 22-04-2016 TOLA_RS03955 b657878cf1699bd3c3d328d45c882cfc 105 Hamap MF_02117 N(2)-fixation sustaining protein CowN [cowN]. 14 105 25.7 T 22-04-2016 IPR024899 Nitrogen fixation-sustaining protein CowN GO:0009399 TOLA_RS04590 ec8568ed82c0ea8af7b7c29ebac2481f 223 PANTHER PTHR11264:SF10 3 219 9.8E-161 T 22-04-2016 TOLA_RS04590 ec8568ed82c0ea8af7b7c29ebac2481f 223 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 1 218 40.175 T 22-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 TOLA_RS04590 ec8568ed82c0ea8af7b7c29ebac2481f 223 Pfam PF03167 Uracil DNA glycosylase superfamily 50 206 2.9E-25 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like TOLA_RS04590 ec8568ed82c0ea8af7b7c29ebac2481f 223 SMART SM00987 46 207 1.1E-38 T 22-04-2016 TOLA_RS04590 ec8568ed82c0ea8af7b7c29ebac2481f 223 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 54 63 - T 22-04-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 TOLA_RS04590 ec8568ed82c0ea8af7b7c29ebac2481f 223 PANTHER PTHR11264 3 219 9.8E-161 T 22-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 TOLA_RS04590 ec8568ed82c0ea8af7b7c29ebac2481f 223 SMART SM00986 46 207 1.1E-38 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like TOLA_RS04590 ec8568ed82c0ea8af7b7c29ebac2481f 223 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 2 210 1.1E-87 T 22-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 TOLA_RS04590 ec8568ed82c0ea8af7b7c29ebac2481f 223 Gene3D G3DSA:3.40.470.10 2 219 1.7E-100 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like TOLA_RS04590 ec8568ed82c0ea8af7b7c29ebac2481f 223 SUPERFAMILY SSF52141 3 219 6.32E-96 T 22-04-2016 IPR005122 Uracil-DNA glycosylase-like TOLA_RS09230 5ccbeb52683b13a845c4d10325f4ea0c 110 Pfam PF06296 RelE toxin of RelE / RelB toxin-antitoxin system 15 105 2.6E-8 T 22-04-2016 IPR009387 Toxin HigB-2 TOLA_RS09230 5ccbeb52683b13a845c4d10325f4ea0c 110 PIRSF PIRSF039032 1 110 1.8E-42 T 22-04-2016 IPR009387 Toxin HigB-2 TOLA_RS11015 622751d5d2a785f48cf8e2b1205544e3 405 Gene3D G3DSA:1.20.1250.20 217 397 1.9E-12 T 22-04-2016 TOLA_RS11015 622751d5d2a785f48cf8e2b1205544e3 405 Gene3D G3DSA:1.20.1250.20 21 201 1.3E-24 T 22-04-2016 TOLA_RS11015 622751d5d2a785f48cf8e2b1205544e3 405 PANTHER PTHR23502:SF19 3 389 2.0E-95 T 22-04-2016 TOLA_RS11015 622751d5d2a785f48cf8e2b1205544e3 405 Pfam PF07690 Major Facilitator Superfamily 32 367 1.8E-39 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS11015 622751d5d2a785f48cf8e2b1205544e3 405 SUPERFAMILY SSF103473 19 397 1.22E-60 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS11015 622751d5d2a785f48cf8e2b1205544e3 405 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 23 395 4.4E-84 T 22-04-2016 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 TOLA_RS11015 622751d5d2a785f48cf8e2b1205544e3 405 PANTHER PTHR23502 3 389 2.0E-95 T 22-04-2016 TOLA_RS06280 32a4fab641e7adf5fcac48d8879c814f 397 SUPERFAMILY SSF161098 88 155 1.36E-12 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06280 32a4fab641e7adf5fcac48d8879c814f 397 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 229 391 4.2E-13 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06280 32a4fab641e7adf5fcac48d8879c814f 397 Gene3D G3DSA:1.10.3720.10 87 155 9.8E-14 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06280 32a4fab641e7adf5fcac48d8879c814f 397 Gene3D G3DSA:1.10.3720.10 186 391 6.5E-33 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06280 32a4fab641e7adf5fcac48d8879c814f 397 PANTHER PTHR30085:SF1 255 397 1.2E-152 T 22-04-2016 TOLA_RS06280 32a4fab641e7adf5fcac48d8879c814f 397 PANTHER PTHR30085:SF1 15 176 1.2E-152 T 22-04-2016 TOLA_RS06280 32a4fab641e7adf5fcac48d8879c814f 397 SUPERFAMILY SSF161098 186 378 3.53E-26 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06280 32a4fab641e7adf5fcac48d8879c814f 397 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 87 150 2.0E-16 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 TOLA_RS06280 32a4fab641e7adf5fcac48d8879c814f 397 PANTHER PTHR30085 255 397 1.2E-152 T 22-04-2016 TOLA_RS06280 32a4fab641e7adf5fcac48d8879c814f 397 PANTHER PTHR30085 15 176 1.2E-152 T 22-04-2016 TOLA_RS02165 1a0499efde47fad9342718a95cea32ac 202 PANTHER PTHR30389 1 198 2.2E-96 T 22-04-2016 TOLA_RS02165 1a0499efde47fad9342718a95cea32ac 202 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 12 178 6.3E-67 T 22-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TOLA_RS02165 1a0499efde47fad9342718a95cea32ac 202 SUPERFAMILY SSF117457 3 177 3.79E-59 T 22-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TOLA_RS02165 1a0499efde47fad9342718a95cea32ac 202 Gene3D G3DSA:3.20.130.10 2 178 3.9E-70 T 22-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TOLA_RS02165 1a0499efde47fad9342718a95cea32ac 202 Pfam PF05683 Fumarase C-terminus 9 178 6.2E-42 T 22-04-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TOLA_RS08730 97c4d354da8cb1aff9892e6b8f46e398 173 PANTHER PTHR36570 1 170 6.8E-71 T 22-04-2016 TOLA_RS08730 97c4d354da8cb1aff9892e6b8f46e398 173 Pfam PF02600 Disulfide bond formation protein DsbB 12 160 7.1E-45 T 22-04-2016 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 TOLA_RS08730 97c4d354da8cb1aff9892e6b8f46e398 173 SUPERFAMILY SSF158442 15 161 4.05E-44 T 22-04-2016 TOLA_RS08730 97c4d354da8cb1aff9892e6b8f46e398 173 Gene3D G3DSA:1.20.1550.10 1 167 4.8E-61 T 22-04-2016 IPR023380 Disulphide bond formation protein DsbB-like domain TOLA_RS08730 97c4d354da8cb1aff9892e6b8f46e398 173 PANTHER PTHR36570:SF2 1 170 6.8E-71 T 22-04-2016 TOLA_RS08730 97c4d354da8cb1aff9892e6b8f46e398 173 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 7 168 21.952 T 22-04-2016 IPR022920 Disulphide bond formation protein DsbB TOLA_RS03315 d8d3cbe153c4ba4c46583b6756c33e7b 307 SUPERFAMILY SSF51735 91 272 4.04E-47 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS03315 d8d3cbe153c4ba4c46583b6756c33e7b 307 Gene3D G3DSA:3.40.50.720 92 273 2.8E-53 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS03315 d8d3cbe153c4ba4c46583b6756c33e7b 307 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 102 272 1.2E-46 T 22-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TOLA_RS03315 d8d3cbe153c4ba4c46583b6756c33e7b 307 PANTHER PTHR10996 44 303 9.7E-88 T 22-04-2016 TOLA_RS03315 d8d3cbe153c4ba4c46583b6756c33e7b 307 PANTHER PTHR10996:SF114 44 303 9.7E-88 T 22-04-2016 TOLA_RS09055 3a0d7c9604234003047de0588d353ee9 398 Pfam PF07690 Major Facilitator Superfamily 21 230 2.4E-23 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS09055 3a0d7c9604234003047de0588d353ee9 398 Pfam PF07690 Major Facilitator Superfamily 244 389 1.1E-14 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS09055 3a0d7c9604234003047de0588d353ee9 398 Gene3D G3DSA:1.20.1250.20 16 198 3.1E-25 T 22-04-2016 TOLA_RS09055 3a0d7c9604234003047de0588d353ee9 398 Gene3D G3DSA:1.20.1250.20 238 391 1.7E-21 T 22-04-2016 TOLA_RS09055 3a0d7c9604234003047de0588d353ee9 398 PANTHER PTHR23518:SF2 11 398 6.1E-111 T 22-04-2016 TOLA_RS09055 3a0d7c9604234003047de0588d353ee9 398 SUPERFAMILY SSF103473 11 391 1.83E-59 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS09055 3a0d7c9604234003047de0588d353ee9 398 PANTHER PTHR23518 11 398 6.1E-111 T 22-04-2016 TOLA_RS15025 fa09317fc2313d7cb7e40aad56f72e19 212 PANTHER PTHR36573 1 212 1.5E-62 T 22-04-2016 TOLA_RS15025 fa09317fc2313d7cb7e40aad56f72e19 212 PIRSF PIRSF004649 1 211 1.5E-59 T 22-04-2016 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC TOLA_RS15025 fa09317fc2313d7cb7e40aad56f72e19 212 Gene3D G3DSA:1.10.10.640 173 203 1.6E-14 T 22-04-2016 IPR023094 Toluene tolerance protein, alpha-helical TOLA_RS15025 fa09317fc2313d7cb7e40aad56f72e19 212 Gene3D G3DSA:1.10.10.640 76 112 1.6E-14 T 22-04-2016 IPR023094 Toluene tolerance protein, alpha-helical TOLA_RS15025 fa09317fc2313d7cb7e40aad56f72e19 212 Pfam PF05494 MlaC protein 34 199 2.4E-51 T 22-04-2016 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC TOLA_RS15025 fa09317fc2313d7cb7e40aad56f72e19 212 Gene3D G3DSA:3.10.450.50 115 172 1.1E-21 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS15025 fa09317fc2313d7cb7e40aad56f72e19 212 Gene3D G3DSA:3.10.450.50 27 71 1.1E-21 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS15595 90470ed376a187d2a6b37dbd36a92156 345 Pfam PF04116 Fatty acid hydroxylase superfamily 139 284 1.1E-27 T 22-04-2016 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 TOLA_RS15595 90470ed376a187d2a6b37dbd36a92156 345 PANTHER PTHR11863:SF2 213 285 1.7E-16 T 22-04-2016 TOLA_RS15595 90470ed376a187d2a6b37dbd36a92156 345 PANTHER PTHR11863:SF2 128 197 1.7E-16 T 22-04-2016 TOLA_RS15595 90470ed376a187d2a6b37dbd36a92156 345 PANTHER PTHR11863 213 285 1.7E-16 T 22-04-2016 TOLA_RS15595 90470ed376a187d2a6b37dbd36a92156 345 PANTHER PTHR11863 128 197 1.7E-16 T 22-04-2016 TOLA_RS15760 6f44a5599166945fa852a54fdf48c543 317 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS15760 6f44a5599166945fa852a54fdf48c543 317 Gene3D G3DSA:3.20.20.70 3 314 1.3E-126 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS15760 6f44a5599166945fa852a54fdf48c543 317 PANTHER PTHR10683 2 316 8.9E-169 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS15760 6f44a5599166945fa852a54fdf48c543 317 SUPERFAMILY SSF51569 2 315 1.47E-112 T 22-04-2016 TOLA_RS15760 6f44a5599166945fa852a54fdf48c543 317 Pfam PF00923 Transaldolase 14 311 2.0E-100 T 22-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS15760 6f44a5599166945fa852a54fdf48c543 317 Hamap MF_00492 Transaldolase [tal]. 2 316 50.741 T 22-04-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS15760 6f44a5599166945fa852a54fdf48c543 317 TIGRFAM TIGR00874 talAB: transaldolase 4 315 2.0E-146 T 22-04-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS15760 6f44a5599166945fa852a54fdf48c543 317 ProSitePatterns PS00958 Transaldolase active site. 129 146 - T 22-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 TOLA_RS15760 6f44a5599166945fa852a54fdf48c543 317 PANTHER PTHR10683:SF18 2 316 8.9E-169 T 22-04-2016 TOLA_RS12405 8194a1c9f557aeb2749092a4dd93078c 120 Pfam PF11190 Protein of unknown function (DUF2976) 33 119 2.7E-33 T 22-04-2016 IPR021356 Integrating conjugative element protein PFL4702 TOLA_RS12405 8194a1c9f557aeb2749092a4dd93078c 120 TIGRFAM TIGR03745 conj_TIGR03745: integrating conjugative element membrane protein, PFL_4702 family 17 120 6.4E-45 T 22-04-2016 IPR021356 Integrating conjugative element protein PFL4702 TOLA_RS02875 14fe6c684246426a5d19d7a5161f53d5 192 Gene3D G3DSA:2.40.128.110 25 192 4.2E-52 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TOLA_RS02875 14fe6c684246426a5d19d7a5161f53d5 192 PANTHER PTHR34406 1 192 2.6E-44 T 22-04-2016 TOLA_RS02875 14fe6c684246426a5d19d7a5161f53d5 192 SUPERFAMILY SSF101874 24 192 1.57E-51 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TOLA_RS02875 14fe6c684246426a5d19d7a5161f53d5 192 Pfam PF04264 YceI-like domain 28 189 1.0E-37 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TOLA_RS02875 14fe6c684246426a5d19d7a5161f53d5 192 SMART SM00867 27 190 5.7E-62 T 22-04-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TOLA_RS02875 14fe6c684246426a5d19d7a5161f53d5 192 PANTHER PTHR34406:SF1 1 192 2.6E-44 T 22-04-2016 TOLA_RS12460 c89ecb3cd0acae4526d1a54c9c1923e1 465 TIGRFAM TIGR03755 conj_TIGR03755: integrating conjugative element protein, PFL_4711 family 49 458 3.1E-177 T 22-04-2016 IPR021204 Integrating conjugative element protein, PFL4711 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 341 1.6E-63 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 Gene3D G3DSA:3.50.50.60 2 137 2.6E-21 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 Gene3D G3DSA:3.50.50.60 175 354 7.0E-28 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 175 193 4.0E-14 T 22-04-2016 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 4.0E-14 T 22-04-2016 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 4.0E-14 T 22-04-2016 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 320 4.0E-14 T 22-04-2016 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 PANTHER PTHR22912 2 40 4.0E-31 T 22-04-2016 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 PANTHER PTHR22912 58 153 4.0E-31 T 22-04-2016 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 PANTHER PTHR22912 211 365 4.0E-31 T 22-04-2016 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 PANTHER PTHR22912 174 195 4.0E-31 T 22-04-2016 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.4E-10 T 22-04-2016 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 313 320 2.4E-10 T 22-04-2016 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 175 200 2.4E-10 T 22-04-2016 TOLA_RS07840 5d67df21402529e45f79cf387cc637b7 437 SUPERFAMILY SSF51905 1 344 2.79E-31 T 22-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 Pfam PF14849 YidC periplasmic domain 63 347 2.7E-80 T 22-04-2016 IPR028053 Membrane insertase YidC, N-terminal TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 356 1.7E-101 T 22-04-2016 IPR028053 Membrane insertase YidC, N-terminal TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 Pfam PF02096 60Kd inner membrane protein 358 535 1.1E-60 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PRINTS PR01900 YidC translocation/secretion protein signature 492 516 7.7E-28 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PRINTS PR01900 YidC translocation/secretion protein signature 472 487 7.7E-28 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PRINTS PR01900 YidC translocation/secretion protein signature 343 359 7.7E-28 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PRINTS PR00701 60kDa inner membrane protein signature 503 526 1.4E-93 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PRINTS PR00701 60kDa inner membrane protein signature 2 23 1.4E-93 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PRINTS PR00701 60kDa inner membrane protein signature 466 488 1.4E-93 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PRINTS PR00701 60kDa inner membrane protein signature 328 348 1.4E-93 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PRINTS PR00701 60kDa inner membrane protein signature 248 263 1.4E-93 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PRINTS PR00701 60kDa inner membrane protein signature 158 178 1.4E-93 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PRINTS PR00701 60kDa inner membrane protein signature 215 233 1.4E-93 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PRINTS PR00701 60kDa inner membrane protein signature 68 89 1.4E-93 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PRINTS PR00701 60kDa inner membrane protein signature 419 442 1.4E-93 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 539 24.887 T 22-04-2016 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 357 536 2.2E-71 T 22-04-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PANTHER PTHR12428 165 549 3.3E-127 T 22-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TOLA_RS16240 956a590cc1223adb2a68cb38560f72f3 549 PANTHER PTHR12428:SF14 165 549 3.3E-127 T 22-04-2016 TOLA_RS04110 9044380daf66e5f41447cddc42d2b86d 302 SUPERFAMILY SSF51430 10 299 8.12E-69 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS04110 9044380daf66e5f41447cddc42d2b86d 302 PANTHER PTHR11732:SF10 2 301 5.2E-145 T 22-04-2016 TOLA_RS04110 9044380daf66e5f41447cddc42d2b86d 302 Pfam PF00248 Aldo/keto reductase family 19 294 3.0E-57 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS04110 9044380daf66e5f41447cddc42d2b86d 302 Gene3D G3DSA:3.20.20.100 10 300 7.8E-60 T 22-04-2016 IPR023210 NADP-dependent oxidoreductase domain TOLA_RS04110 9044380daf66e5f41447cddc42d2b86d 302 PANTHER PTHR11732 2 301 5.2E-145 T 22-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta TOLA_RS04110 9044380daf66e5f41447cddc42d2b86d 302 PRINTS PR00069 Aldo-keto reductase signature 114 132 1.4E-7 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS04110 9044380daf66e5f41447cddc42d2b86d 302 PRINTS PR00069 Aldo-keto reductase signature 145 162 1.4E-7 T 22-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TOLA_RS01335 1a7838d735da0e252c7e654d5e5f0710 346 Pfam PF09925 Predicted membrane protein (DUF2157) 13 122 2.1E-8 T 22-04-2016 IPR018677 Domain of unknown function DUF2157 TOLA_RS10470 4e3787e857e3a85b70ba177261c53b11 272 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 26 272 1.0E-127 T 22-04-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 TOLA_RS10470 4e3787e857e3a85b70ba177261c53b11 272 Gene3D G3DSA:3.40.50.300 24 266 2.5E-71 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10470 4e3787e857e3a85b70ba177261c53b11 272 Pfam PF00005 ABC transporter 43 197 1.1E-32 T 22-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TOLA_RS10470 4e3787e857e3a85b70ba177261c53b11 272 PANTHER PTHR24220:SF585 27 271 1.0E-142 T 22-04-2016 TOLA_RS10470 4e3787e857e3a85b70ba177261c53b11 272 SUPERFAMILY SSF52540 22 260 6.63E-63 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS10470 4e3787e857e3a85b70ba177261c53b11 272 SMART SM00382 50 253 3.3E-16 T 22-04-2016 IPR003593 AAA+ ATPase domain TOLA_RS10470 4e3787e857e3a85b70ba177261c53b11 272 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 22-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TOLA_RS10470 4e3787e857e3a85b70ba177261c53b11 272 PANTHER PTHR24220 27 271 1.0E-142 T 22-04-2016 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 PANTHER PTHR10520 5 271 2.0E-126 T 22-04-2016 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 PIRSF PIRSF036480 1 278 2.8E-108 T 22-04-2016 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 SUPERFAMILY SSF55021 4 60 6.87E-7 T 22-04-2016 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 105 132 9.0E-58 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 38 50 9.0E-58 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 83 105 9.0E-58 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 229 251 9.0E-58 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 9.0E-58 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 276 9.0E-58 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 Gene3D G3DSA:3.30.70.260 2 68 2.1E-10 T 22-04-2016 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 Gene3D G3DSA:3.40.50.170 81 274 3.6E-52 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 SUPERFAMILY SSF53328 82 278 5.36E-56 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 277 44.368 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 Pfam PF00551 Formyl transferase 82 259 6.7E-43 T 22-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 PANTHER PTHR10520:SF7 5 271 2.0E-126 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 TOLA_RS03295 a4264c547943219842e74b85def813ac 278 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 4 277 7.0E-116 T 22-04-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 TOLA_RS01275 a18e9308f7d7d98b1ff55720a69f4566 675 Pfam PF05170 AsmA family 440 590 3.3E-12 T 22-04-2016 IPR007844 AsmA TOLA_RS04300 19edf5ceff0b349f9e7d001f8dcf29e7 286 SUPERFAMILY SSF54427 164 283 1.27E-14 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS04300 19edf5ceff0b349f9e7d001f8dcf29e7 286 PANTHER PTHR41542:SF1 1 286 2.0E-67 T 22-04-2016 TOLA_RS04300 19edf5ceff0b349f9e7d001f8dcf29e7 286 PANTHER PTHR41542 1 286 2.0E-67 T 22-04-2016 TOLA_RS04300 19edf5ceff0b349f9e7d001f8dcf29e7 286 Pfam PF04280 Tim44-like domain 165 284 7.0E-15 T 22-04-2016 IPR007379 Tim44-like domain TOLA_RS04300 19edf5ceff0b349f9e7d001f8dcf29e7 286 SMART SM00978 154 285 6.8E-34 T 22-04-2016 IPR007379 Tim44-like domain TOLA_RS02810 6facb32b6050056a2147ef04a77b9eb0 93 PANTHER PTHR35601 1 93 1.2E-42 T 22-04-2016 TOLA_RS02810 6facb32b6050056a2147ef04a77b9eb0 93 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 5 84 3.3E-9 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TOLA_RS02810 6facb32b6050056a2147ef04a77b9eb0 93 PANTHER PTHR35601:SF2 1 93 1.2E-42 T 22-04-2016 TOLA_RS02810 6facb32b6050056a2147ef04a77b9eb0 93 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 82 4.8E-12 T 22-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TOLA_RS02810 6facb32b6050056a2147ef04a77b9eb0 93 SUPERFAMILY SSF143011 1 83 1.83E-23 T 22-04-2016 TOLA_RS13045 b12d92ddc164a5423a9f0fabfb8930ca 105 SUPERFAMILY SSF54913 1 100 6.34E-26 T 22-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta TOLA_RS13045 b12d92ddc164a5423a9f0fabfb8930ca 105 Pfam PF02641 Uncharacterized ACR, COG1993 5 85 1.1E-15 T 22-04-2016 IPR003793 Domain of unknown function DUF190 TOLA_RS13045 b12d92ddc164a5423a9f0fabfb8930ca 105 Gene3D G3DSA:3.30.70.120 1 104 1.3E-27 T 22-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TOLA_RS08610 91df34d4244805ca24801bbd9d36a0d0 209 PANTHER PTHR39453 1 204 8.4E-91 T 22-04-2016 TOLA_RS08610 91df34d4244805ca24801bbd9d36a0d0 209 Pfam PF06130 Phosphate propanoyltransferase 130 196 4.7E-17 T 22-04-2016 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420|UniPathway: UPA00621 TOLA_RS08610 91df34d4244805ca24801bbd9d36a0d0 209 Pfam PF06130 Phosphate propanoyltransferase 23 100 6.5E-28 T 22-04-2016 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420|UniPathway: UPA00621 TOLA_RS08610 91df34d4244805ca24801bbd9d36a0d0 209 PIRSF PIRSF010130 1 209 1.9E-85 T 22-04-2016 IPR008300 Phosphate propanoyltransferase GO:0016747 KEGG: 00561+2.3.1.22|KEGG: 00640+2.3.1.222|MetaCyc: PWY-5437|MetaCyc: PWY-7013|MetaCyc: PWY-7420|UniPathway: UPA00621 TOLA_RS08610 91df34d4244805ca24801bbd9d36a0d0 209 PANTHER PTHR39453:SF1 1 204 8.4E-91 T 22-04-2016 TOLA_RS07440 56d4d6d89a81dd77aa1cdfcb22736cc8 250 Pfam PF02698 DUF218 domain 79 242 6.9E-24 T 22-04-2016 IPR003848 Domain of unknown function DUF218 TOLA_RS07440 56d4d6d89a81dd77aa1cdfcb22736cc8 250 Gene3D G3DSA:3.40.50.620 74 208 1.3E-12 T 22-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TOLA_RS07440 56d4d6d89a81dd77aa1cdfcb22736cc8 250 PANTHER PTHR30336 1 249 8.0E-48 T 22-04-2016 TOLA_RS07440 56d4d6d89a81dd77aa1cdfcb22736cc8 250 PANTHER PTHR30336:SF1 1 249 8.0E-48 T 22-04-2016 TOLA_RS16220 01d37d1a747f4a44f75c59f5d41370d2 320 Pfam PF04198 Putative sugar-binding domain 61 315 3.6E-78 T 22-04-2016 IPR007324 Sugar-binding domain, putative GO:0030246 TOLA_RS16220 01d37d1a747f4a44f75c59f5d41370d2 320 PANTHER PTHR34294:SF5 5 320 2.4E-104 T 22-04-2016 TOLA_RS16220 01d37d1a747f4a44f75c59f5d41370d2 320 Gene3D G3DSA:1.10.10.10 24 58 6.5E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS16220 01d37d1a747f4a44f75c59f5d41370d2 320 Gene3D G3DSA:3.40.50.1360 64 318 9.7E-76 T 22-04-2016 TOLA_RS16220 01d37d1a747f4a44f75c59f5d41370d2 320 PANTHER PTHR34294 5 320 2.4E-104 T 22-04-2016 TOLA_RS16220 01d37d1a747f4a44f75c59f5d41370d2 320 SUPERFAMILY SSF100950 65 315 9.57E-69 T 22-04-2016 TOLA_RS02775 a10e4f7babcd981f06159574467b551d 418 Pfam PF00482 Type II secretion system (T2SS), protein F 84 206 5.2E-32 T 22-04-2016 IPR018076 Type II secretion system F domain TOLA_RS02775 a10e4f7babcd981f06159574467b551d 418 Pfam PF00482 Type II secretion system (T2SS), protein F 288 409 2.8E-28 T 22-04-2016 IPR018076 Type II secretion system F domain TOLA_RS02775 a10e4f7babcd981f06159574467b551d 418 PRINTS PR00812 Bacterial general secretion pathway protein F signature 398 417 1.1E-19 T 22-04-2016 IPR003004 GspF/PilC family TOLA_RS02775 a10e4f7babcd981f06159574467b551d 418 PRINTS PR00812 Bacterial general secretion pathway protein F signature 178 206 1.1E-19 T 22-04-2016 IPR003004 GspF/PilC family TOLA_RS02775 a10e4f7babcd981f06159574467b551d 418 PRINTS PR00812 Bacterial general secretion pathway protein F signature 382 396 1.1E-19 T 22-04-2016 IPR003004 GspF/PilC family TOLA_RS02775 a10e4f7babcd981f06159574467b551d 418 PRINTS PR00812 Bacterial general secretion pathway protein F signature 79 91 1.1E-19 T 22-04-2016 IPR003004 GspF/PilC family TOLA_RS02775 a10e4f7babcd981f06159574467b551d 418 PANTHER PTHR30012:SF0 22 418 7.2E-159 T 22-04-2016 TOLA_RS02775 a10e4f7babcd981f06159574467b551d 418 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 178 206 - T 22-04-2016 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 TOLA_RS02775 a10e4f7babcd981f06159574467b551d 418 PANTHER PTHR30012 22 418 7.2E-159 T 22-04-2016 TOLA_RS15480 d960e74525199cf5516142c7cc1d585f 106 Pfam PF06611 Protein of unknown function (DUF1145) 5 56 1.6E-7 T 22-04-2016 IPR009525 Protein of unknown function DUF1145 TOLA_RS06855 43a13e65705b4af48b99b0871c57a009 277 PANTHER PTHR35811 5 250 3.3E-56 T 22-04-2016 TOLA_RS06855 43a13e65705b4af48b99b0871c57a009 277 Pfam PF01936 NYN domain 18 151 5.3E-30 T 22-04-2016 IPR021139 NYN domain, limkain-b1-type TOLA_RS06855 43a13e65705b4af48b99b0871c57a009 277 Pfam PF12872 OST-HTH/LOTUS domain 203 266 5.4E-16 T 22-04-2016 IPR025605 OST-HTH/LOTUS domain TOLA_RS06855 43a13e65705b4af48b99b0871c57a009 277 PANTHER PTHR35811:SF1 5 250 3.3E-56 T 22-04-2016 TOLA_RS06855 43a13e65705b4af48b99b0871c57a009 277 Gene3D G3DSA:3.40.50.1010 12 153 5.2E-28 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS03795 328f1702a236f46ed2f4a16939efbb58 488 Pfam PF04233 Phage Mu protein F like protein 55 167 8.7E-12 T 22-04-2016 IPR006528 Phage head morphogenesis domain TOLA_RS03795 328f1702a236f46ed2f4a16939efbb58 488 SUPERFAMILY SSF55486 354 477 4.54E-10 T 22-04-2016 TOLA_RS03795 328f1702a236f46ed2f4a16939efbb58 488 Gene3D G3DSA:3.40.390.10 404 478 4.7E-6 T 22-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 TOLA_RS04725 5ec3523fd98164b617c4dc93b3a8af6c 358 Pfam PF01594 Domain of unknown function DUF20 20 345 2.4E-66 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like TOLA_RS04725 5ec3523fd98164b617c4dc93b3a8af6c 358 PANTHER PTHR21716 7 355 2.1E-123 T 22-04-2016 IPR002549 Transmembrane protein TqsA-like TOLA_RS04725 5ec3523fd98164b617c4dc93b3a8af6c 358 PANTHER PTHR21716:SF19 7 355 2.1E-123 T 22-04-2016 TOLA_RS13325 cc45fee039dec8be7ae4dbbfac5d8561 507 Pfam PF02369 Bacterial Ig-like domain (group 1) 72 150 1.8E-8 T 22-04-2016 IPR003344 Big-1 (bacterial Ig-like domain 1) domain TOLA_RS13325 cc45fee039dec8be7ae4dbbfac5d8561 507 Gene3D G3DSA:2.60.40.920 74 151 2.6E-8 T 22-04-2016 IPR003344 Big-1 (bacterial Ig-like domain 1) domain TOLA_RS13325 cc45fee039dec8be7ae4dbbfac5d8561 507 SUPERFAMILY SSF49373 73 148 6.02E-9 T 22-04-2016 IPR008964 Invasin/intimin cell-adhesion fragments TOLA_RS09495 983399c06e6709f7e1f4aa669211c245 83 Pfam PF01381 Helix-turn-helix 14 64 2.5E-8 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS09495 983399c06e6709f7e1f4aa669211c245 83 SMART SM00530 11 66 1.3E-6 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS09495 983399c06e6709f7e1f4aa669211c245 83 SUPERFAMILY SSF47413 5 65 6.48E-12 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS09495 983399c06e6709f7e1f4aa669211c245 83 Gene3D G3DSA:1.10.260.40 6 64 2.2E-12 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS09325 ae811b8375a1cea167eaa4130e4c060a 312 Gene3D G3DSA:3.40.50.2300 143 304 5.1E-48 T 22-04-2016 TOLA_RS09325 ae811b8375a1cea167eaa4130e4c060a 312 Pfam PF13407 Periplasmic binding protein domain 28 283 4.3E-57 T 22-04-2016 IPR025997 Periplasmic binding protein TOLA_RS09325 ae811b8375a1cea167eaa4130e4c060a 312 PANTHER PTHR32196:SF9 28 297 4.8E-79 T 22-04-2016 TOLA_RS09325 ae811b8375a1cea167eaa4130e4c060a 312 SUPERFAMILY SSF53822 25 304 8.39E-75 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS09325 ae811b8375a1cea167eaa4130e4c060a 312 Gene3D G3DSA:3.40.50.2300 27 142 4.3E-33 T 22-04-2016 TOLA_RS09325 ae811b8375a1cea167eaa4130e4c060a 312 PANTHER PTHR32196 28 297 4.8E-79 T 22-04-2016 TOLA_RS02865 d64053792f8e72514a3f0908098a4f16 180 PANTHER PTHR30529 1 178 3.5E-60 T 22-04-2016 TOLA_RS02865 d64053792f8e72514a3f0908098a4f16 180 Pfam PF01292 Prokaryotic cytochrome b561 4 175 7.0E-30 T 22-04-2016 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 TOLA_RS02865 d64053792f8e72514a3f0908098a4f16 180 Gene3D G3DSA:1.20.950.20 91 159 0.001 T 22-04-2016 TOLA_RS02865 d64053792f8e72514a3f0908098a4f16 180 PANTHER PTHR30529:SF5 1 178 3.5E-60 T 22-04-2016 TOLA_RS02865 d64053792f8e72514a3f0908098a4f16 180 SUPERFAMILY SSF81342 3 176 1.18E-39 T 22-04-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 TOLA_RS00765 4802f89811ba2337197cc76a4149d0d8 151 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 4.3E-35 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type TOLA_RS00765 4802f89811ba2337197cc76a4149d0d8 151 Gene3D G3DSA:1.10.10.10 1 134 6.6E-40 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS00765 4802f89811ba2337197cc76a4149d0d8 151 PANTHER PTHR33221 2 151 1.2E-54 T 22-04-2016 TOLA_RS00765 4802f89811ba2337197cc76a4149d0d8 151 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 22-04-2016 IPR030489 Transcription regulator Rrf2-type, conserved site TOLA_RS00765 4802f89811ba2337197cc76a4149d0d8 151 PANTHER PTHR33221:SF4 2 151 1.2E-54 T 22-04-2016 TOLA_RS00765 4802f89811ba2337197cc76a4149d0d8 151 Pfam PF02082 Transcriptional regulator 1 80 9.7E-24 T 22-04-2016 IPR000944 Transcription regulator Rrf2-type TOLA_RS00765 4802f89811ba2337197cc76a4149d0d8 151 SUPERFAMILY SSF46785 2 132 1.02E-30 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS14595 b27431ce9f2996c493b803bac6ae9a2f 177 Pfam PF00583 Acetyltransferase (GNAT) family 95 153 4.9E-7 T 22-04-2016 IPR000182 GNAT domain GO:0008080 TOLA_RS14595 b27431ce9f2996c493b803bac6ae9a2f 177 SUPERFAMILY SSF55729 60 156 2.88E-13 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS14595 b27431ce9f2996c493b803bac6ae9a2f 177 PANTHER PTHR36449 1 175 8.5E-52 T 22-04-2016 TOLA_RS14595 b27431ce9f2996c493b803bac6ae9a2f 177 Gene3D G3DSA:3.40.630.30 90 169 3.7E-12 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS15085 2a8522487d594b875ee6f3d70ce10c53 288 PANTHER PTHR30448 1 283 8.7E-133 T 22-04-2016 TOLA_RS15085 2a8522487d594b875ee6f3d70ce10c53 288 PANTHER PTHR30448:SF0 1 283 8.7E-133 T 22-04-2016 TOLA_RS15085 2a8522487d594b875ee6f3d70ce10c53 288 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 283 40.182 T 22-04-2016 IPR005337 RapZ-like family GO:0005524 TOLA_RS15085 2a8522487d594b875ee6f3d70ce10c53 288 Pfam PF03668 P-loop ATPase protein family 1 283 2.2E-109 T 22-04-2016 IPR005337 RapZ-like family GO:0005524 TOLA_RS15085 2a8522487d594b875ee6f3d70ce10c53 288 PIRSF PIRSF005052 1 286 3.7E-108 T 22-04-2016 IPR005337 RapZ-like family GO:0005524 TOLA_RS15085 2a8522487d594b875ee6f3d70ce10c53 288 Gene3D G3DSA:3.40.50.300 1 153 1.8E-14 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS15085 2a8522487d594b875ee6f3d70ce10c53 288 SUPERFAMILY SSF52540 1 153 6.74E-13 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS09165 20815b430b0247e285ae594ac37eb9e7 145 Gene3D G3DSA:3.10.450.50 23 143 3.8E-29 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS09165 20815b430b0247e285ae594ac37eb9e7 145 Pfam PF14534 Domain of unknown function (DUF4440) 34 135 7.0E-14 T 22-04-2016 IPR027843 Domain of unknown function DUF4440 TOLA_RS09165 20815b430b0247e285ae594ac37eb9e7 145 SUPERFAMILY SSF54427 28 140 4.75E-21 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS00625 33c320cc1e27141e5450be5c77c3d2cf 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 3.3E-23 T 22-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00625 33c320cc1e27141e5450be5c77c3d2cf 37 PANTHER PTHR18804 1 37 1.8E-17 T 22-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00625 33c320cc1e27141e5450be5c77c3d2cf 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 3.0E-8 T 22-04-2016 TOLA_RS00625 33c320cc1e27141e5450be5c77c3d2cf 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.791 T 22-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00625 33c320cc1e27141e5450be5c77c3d2cf 37 Pfam PF00444 Ribosomal protein L36 1 37 1.5E-18 T 22-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00625 33c320cc1e27141e5450be5c77c3d2cf 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 22-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS00625 33c320cc1e27141e5450be5c77c3d2cf 37 SUPERFAMILY SSF57840 1 37 1.7E-16 T 22-04-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS07550 65eadac60d1914ef121e48632d8d033b 101 PANTHER PTHR34581 2 100 1.4E-40 T 22-04-2016 TOLA_RS07550 65eadac60d1914ef121e48632d8d033b 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 2.8E-24 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS07550 65eadac60d1914ef121e48632d8d033b 101 PANTHER PTHR34581:SF2 2 100 1.4E-40 T 22-04-2016 TOLA_RS07550 65eadac60d1914ef121e48632d8d033b 101 SUPERFAMILY SSF52794 1 100 2.56E-35 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS07550 65eadac60d1914ef121e48632d8d033b 101 Gene3D G3DSA:3.40.50.270 1 100 7.5E-38 T 22-04-2016 TOLA_RS12495 ad7be0c8d986e03c117bd232176c2410 79 SUPERFAMILY SSF51735 2 73 6.88E-13 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS12495 ad7be0c8d986e03c117bd232176c2410 79 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 2 71 2.4E-10 T 22-04-2016 TOLA_RS12495 ad7be0c8d986e03c117bd232176c2410 79 Gene3D G3DSA:3.40.50.720 2 74 8.7E-14 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS14730 5957d103a1d5756b89c607a130b0948c 279 Pfam PF00756 Putative esterase 24 272 5.1E-64 T 22-04-2016 IPR000801 Putative esterase TOLA_RS14730 5957d103a1d5756b89c607a130b0948c 279 PANTHER PTHR10061 3 279 3.0E-169 T 22-04-2016 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801 TOLA_RS14730 5957d103a1d5756b89c607a130b0948c 279 SUPERFAMILY SSF53474 4 277 1.22E-90 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS14730 5957d103a1d5756b89c607a130b0948c 279 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 6 275 6.0E-126 T 22-04-2016 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801 TOLA_RS14730 5957d103a1d5756b89c607a130b0948c 279 Gene3D G3DSA:3.40.50.1820 4 277 3.1E-78 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS03810 38094e9d80885734a1070215ccc8a346 363 PIRSF PIRSF016624 4 363 1.8E-112 T 22-04-2016 IPR012106 Protease, Mu phage/prophage I type TOLA_RS03810 38094e9d80885734a1070215ccc8a346 363 Pfam PF10123 Mu-like prophage I protein 25 358 4.1E-105 T 22-04-2016 IPR012106 Protease, Mu phage/prophage I type TOLA_RS01060 865a37cefa4a222d031516435f1e61f0 137 Gene3D G3DSA:3.10.450.40 20 124 2.3E-13 T 22-04-2016 TOLA_RS01060 865a37cefa4a222d031516435f1e61f0 137 SUPERFAMILY SSF160719 23 127 2.88E-20 T 22-04-2016 TOLA_RS01060 865a37cefa4a222d031516435f1e61f0 137 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 4 127 5.4E-30 T 22-04-2016 IPR017737 Type VI secretion system, lysozyme-related protein TOLA_RS01060 865a37cefa4a222d031516435f1e61f0 137 Pfam PF04965 Gene 25-like lysozyme 25 112 6.8E-15 T 22-04-2016 IPR007048 GpW/Gp25/anti-adapter protein IraD TOLA_RS10320 a3ffbcb92c31c860fbfac876216ead09 373 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 3 368 3.8E-187 T 22-04-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS10320 a3ffbcb92c31c860fbfac876216ead09 373 Gene3D G3DSA:3.20.20.105 1 367 9.9E-172 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS10320 a3ffbcb92c31c860fbfac876216ead09 373 SUPERFAMILY SSF51713 1 364 1.31E-163 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS10320 a3ffbcb92c31c860fbfac876216ead09 373 Pfam PF01702 Queuine tRNA-ribosyltransferase 126 361 6.5E-93 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS10320 a3ffbcb92c31c860fbfac876216ead09 373 PANTHER PTHR21148:SF26 1 364 1.0E-185 T 22-04-2016 TOLA_RS10320 a3ffbcb92c31c860fbfac876216ead09 373 PANTHER PTHR21148 1 364 1.0E-185 T 22-04-2016 TOLA_RS10320 a3ffbcb92c31c860fbfac876216ead09 373 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 367 2.9E-177 T 22-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS10320 a3ffbcb92c31c860fbfac876216ead09 373 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 359 57.985 T 22-04-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 TOLA_RS11825 046d22506b86ebcfac7b5058ba3fd38b 207 Gene3D G3DSA:1.10.3890.10 2 206 4.2E-78 T 22-04-2016 IPR007451 Uncharacterised protein family UPF0274 TOLA_RS11825 046d22506b86ebcfac7b5058ba3fd38b 207 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 9 196 1.0E-53 T 22-04-2016 IPR007451 Uncharacterised protein family UPF0274 TOLA_RS11825 046d22506b86ebcfac7b5058ba3fd38b 207 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 205 35.595 T 22-04-2016 IPR007451 Uncharacterised protein family UPF0274 TOLA_RS11825 046d22506b86ebcfac7b5058ba3fd38b 207 SUPERFAMILY SSF101322 5 206 2.48E-71 T 22-04-2016 IPR007451 Uncharacterised protein family UPF0274 TOLA_RS11825 046d22506b86ebcfac7b5058ba3fd38b 207 Pfam PF04356 Protein of unknown function (DUF489) 8 197 4.9E-75 T 22-04-2016 IPR007451 Uncharacterised protein family UPF0274 TOLA_RS11825 046d22506b86ebcfac7b5058ba3fd38b 207 PANTHER PTHR38100 2 207 2.1E-80 T 22-04-2016 TOLA_RS11825 046d22506b86ebcfac7b5058ba3fd38b 207 PANTHER PTHR38100:SF1 2 207 2.1E-80 T 22-04-2016 TOLA_RS04145 95602294ab7a8b7a8e1940656a6089d1 424 Gene3D G3DSA:1.20.1440.110 101 151 9.5E-8 T 22-04-2016 TOLA_RS04145 95602294ab7a8b7a8e1940656a6089d1 424 Gene3D G3DSA:3.40.50.1820 180 309 2.5E-23 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS04145 95602294ab7a8b7a8e1940656a6089d1 424 Gene3D G3DSA:3.40.50.1820 356 419 2.5E-23 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS04145 95602294ab7a8b7a8e1940656a6089d1 424 SUPERFAMILY SSF53474 52 422 3.37E-52 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS04145 95602294ab7a8b7a8e1940656a6089d1 424 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 5 419 8.6E-132 T 22-04-2016 IPR010520 UPF0255 family TOLA_RS02840 86782e3488cd9bafb83c2abeb535edc9 361 PANTHER PTHR33529:SF2 1 360 4.3E-92 T 22-04-2016 TOLA_RS02840 86782e3488cd9bafb83c2abeb535edc9 361 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 1 338 9.0E-108 T 22-04-2016 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 TOLA_RS02840 86782e3488cd9bafb83c2abeb535edc9 361 PANTHER PTHR33529 1 360 4.3E-92 T 22-04-2016 TOLA_RS02840 86782e3488cd9bafb83c2abeb535edc9 361 Pfam PF03739 Predicted permease YjgP/YjgQ family 1 338 3.4E-71 T 22-04-2016 IPR005495 Permease LptG/LptF-related GO:0016021 TOLA_RS15015 cbd07b133749f746bf95ec6ad4004878 84 PANTHER PTHR12735:SF24 5 82 4.7E-29 T 22-04-2016 TOLA_RS15015 cbd07b133749f746bf95ec6ad4004878 84 Gene3D G3DSA:3.30.300.90 1 80 5.7E-28 T 22-04-2016 IPR002634 BolA protein TOLA_RS15015 cbd07b133749f746bf95ec6ad4004878 84 PIRSF PIRSF003113 1 83 5.1E-23 T 22-04-2016 IPR002634 BolA protein TOLA_RS15015 cbd07b133749f746bf95ec6ad4004878 84 Pfam PF01722 BolA-like protein 22 74 1.8E-15 T 22-04-2016 IPR002634 BolA protein TOLA_RS15015 cbd07b133749f746bf95ec6ad4004878 84 SUPERFAMILY SSF82657 1 82 1.57E-29 T 22-04-2016 IPR002634 BolA protein TOLA_RS15015 cbd07b133749f746bf95ec6ad4004878 84 PANTHER PTHR12735 5 82 4.7E-29 T 22-04-2016 TOLA_RS12090 858b25da879e6002c069610f1b6333a0 85 PANTHER PTHR15893 1 85 2.7E-49 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12090 858b25da879e6002c069610f1b6333a0 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 22-04-2016 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12090 858b25da879e6002c069610f1b6333a0 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.567 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12090 858b25da879e6002c069610f1b6333a0 85 Gene3D G3DSA:2.40.50.100 20 82 1.5E-30 T 22-04-2016 TOLA_RS12090 858b25da879e6002c069610f1b6333a0 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 5.0E-16 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12090 858b25da879e6002c069610f1b6333a0 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 1.6E-41 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12090 858b25da879e6002c069610f1b6333a0 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 3.9E-37 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12090 858b25da879e6002c069610f1b6333a0 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 3.9E-37 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12090 858b25da879e6002c069610f1b6333a0 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 3.9E-37 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12090 858b25da879e6002c069610f1b6333a0 85 Pfam PF01016 Ribosomal L27 protein 2 82 4.0E-38 T 22-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS12090 858b25da879e6002c069610f1b6333a0 85 SUPERFAMILY SSF110324 2 82 1.12E-33 T 22-04-2016 TOLA_RS14425 d3cb55133653c61833f5b60fcd9d721d 97 PANTHER PTHR10772 1 97 1.9E-36 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TOLA_RS14425 d3cb55133653c61833f5b60fcd9d721d 97 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 22-04-2016 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 TOLA_RS14425 d3cb55133653c61833f5b60fcd9d721d 97 Hamap MF_00580 10 kDa chaperonin [groS]. 2 96 23.914 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TOLA_RS14425 d3cb55133653c61833f5b60fcd9d721d 97 Gene3D G3DSA:2.30.33.40 1 96 8.4E-32 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TOLA_RS14425 d3cb55133653c61833f5b60fcd9d721d 97 SMART SM00883 2 95 1.3E-47 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TOLA_RS14425 d3cb55133653c61833f5b60fcd9d721d 97 SUPERFAMILY SSF50129 1 96 4.24E-30 T 22-04-2016 IPR011032 GroES-like TOLA_RS14425 d3cb55133653c61833f5b60fcd9d721d 97 Pfam PF00166 Chaperonin 10 Kd subunit 2 95 1.9E-29 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TOLA_RS14425 d3cb55133653c61833f5b60fcd9d721d 97 PRINTS PR00297 10kDa chaperonin signature 25 46 3.4E-28 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TOLA_RS14425 d3cb55133653c61833f5b60fcd9d721d 97 PRINTS PR00297 10kDa chaperonin signature 82 95 3.4E-28 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TOLA_RS14425 d3cb55133653c61833f5b60fcd9d721d 97 PRINTS PR00297 10kDa chaperonin signature 3 18 3.4E-28 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TOLA_RS14425 d3cb55133653c61833f5b60fcd9d721d 97 PRINTS PR00297 10kDa chaperonin signature 60 72 3.4E-28 T 22-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TOLA_RS07580 13daacff39655f149b8b87ed5ca44a5f 630 Gene3D G3DSA:1.10.3470.10 320 629 1.4E-73 T 22-04-2016 IPR029022 ABC transporter, BtuC-like TOLA_RS07580 13daacff39655f149b8b87ed5ca44a5f 630 PANTHER PTHR30472 214 629 9.6E-121 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 TOLA_RS07580 13daacff39655f149b8b87ed5ca44a5f 630 SUPERFAMILY SSF81345 322 629 3.53E-65 T 22-04-2016 IPR029022 ABC transporter, BtuC-like TOLA_RS07580 13daacff39655f149b8b87ed5ca44a5f 630 Gene3D G3DSA:1.10.3470.10 6 298 4.5E-76 T 22-04-2016 IPR029022 ABC transporter, BtuC-like TOLA_RS07580 13daacff39655f149b8b87ed5ca44a5f 630 PANTHER PTHR30472:SF16 214 629 9.6E-121 T 22-04-2016 TOLA_RS07580 13daacff39655f149b8b87ed5ca44a5f 630 Pfam PF01032 FecCD transport family 326 629 4.9E-74 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 TOLA_RS07580 13daacff39655f149b8b87ed5ca44a5f 630 Pfam PF01032 FecCD transport family 5 294 4.5E-71 T 22-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 TOLA_RS07580 13daacff39655f149b8b87ed5ca44a5f 630 SUPERFAMILY SSF81345 14 296 2.62E-60 T 22-04-2016 IPR029022 ABC transporter, BtuC-like TOLA_RS02720 34a44980b5a349c172364829b051b65c 355 Gene3D G3DSA:3.40.50.2000 252 334 3.9E-7 T 22-04-2016 TOLA_RS02720 34a44980b5a349c172364829b051b65c 355 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3 349 1.4E-109 T 22-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS02720 34a44980b5a349c172364829b051b65c 355 SUPERFAMILY SSF53756 4 354 4.71E-122 T 22-04-2016 TOLA_RS02720 34a44980b5a349c172364829b051b65c 355 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 185 333 1.0E-38 T 22-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS02720 34a44980b5a349c172364829b051b65c 355 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 142 2.6E-44 T 22-04-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS02720 34a44980b5a349c172364829b051b65c 355 PANTHER PTHR21015 6 355 2.3E-119 T 22-04-2016 TOLA_RS02720 34a44980b5a349c172364829b051b65c 355 PANTHER PTHR21015:SF22 6 355 2.3E-119 T 22-04-2016 TOLA_RS02720 34a44980b5a349c172364829b051b65c 355 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 355 36.904 T 22-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 TOLA_RS02720 34a44980b5a349c172364829b051b65c 355 Gene3D G3DSA:3.40.50.2000 2 196 1.4E-70 T 22-04-2016 TOLA_RS03555 96b9c97eec14eba80aefb374c05e6a25 91 PANTHER PTHR12962 1 84 5.2E-29 T 22-04-2016 TOLA_RS03555 96b9c97eec14eba80aefb374c05e6a25 91 PANTHER PTHR12962:SF1 1 84 5.2E-29 T 22-04-2016 TOLA_RS03555 96b9c97eec14eba80aefb374c05e6a25 91 PIRSF PIRSF002599 1 89 1.2E-28 T 22-04-2016 IPR012156 Cold shock, CspA GO:0003676 TOLA_RS03555 96b9c97eec14eba80aefb374c05e6a25 91 Pfam PF06961 Protein of unknown function (DUF1294) 11 65 8.3E-26 T 22-04-2016 IPR010718 Protein of unknown function DUF1294 TOLA_RS10440 29a52f99527c68fc4316e2f42ffd0bb3 410 Pfam PF01943 Polysaccharide biosynthesis protein 13 274 8.1E-6 T 22-04-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TOLA_RS09845 0b10428338e7324bfacdeb44b9ea54df 103 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 6 98 8.2E-22 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 TOLA_RS09845 0b10428338e7324bfacdeb44b9ea54df 103 PANTHER PTHR37419:SF1 1 96 1.2E-13 T 22-04-2016 TOLA_RS09845 0b10428338e7324bfacdeb44b9ea54df 103 PANTHER PTHR37419 1 96 1.2E-13 T 22-04-2016 TOLA_RS09845 0b10428338e7324bfacdeb44b9ea54df 103 Pfam PF13657 HipA N-terminal domain 7 98 4.3E-22 T 22-04-2016 IPR017508 HipA, N-terminal subdomain 1 TOLA_RS11990 91d50f75a6fcc24e6b20e6d6653c294c 124 Pfam PF09345 Domain of unknown function (DUF1987) 13 111 4.5E-36 T 22-04-2016 IPR018530 Domain of unknown function DUF1987 TOLA_RS04625 3837b5186969cde9dd3cca66983a079e 651 SUPERFAMILY SSF54001 273 393 3.92E-10 T 22-04-2016 TOLA_RS04625 3837b5186969cde9dd3cca66983a079e 651 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 64 231 4.9E-35 T 22-04-2016 IPR024618 Domain of unknown function DUF3857 TOLA_RS04625 3837b5186969cde9dd3cca66983a079e 651 Pfam PF01841 Transglutaminase-like superfamily 278 349 1.4E-6 T 22-04-2016 IPR002931 Transglutaminase-like TOLA_RS08785 595708b5ddb679a4a973674bbf8f3568 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 6.1E-21 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TOLA_RS08785 595708b5ddb679a4a973674bbf8f3568 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 6.1E-21 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TOLA_RS08785 595708b5ddb679a4a973674bbf8f3568 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 6.1E-21 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TOLA_RS08785 595708b5ddb679a4a973674bbf8f3568 65 PANTHER PTHR33343 1 65 1.5E-28 T 22-04-2016 TOLA_RS08785 595708b5ddb679a4a973674bbf8f3568 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 2.2E-28 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TOLA_RS08785 595708b5ddb679a4a973674bbf8f3568 65 Pfam PF01632 Ribosomal protein L35 2 62 2.7E-25 T 22-04-2016 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS08785 595708b5ddb679a4a973674bbf8f3568 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 19.136 T 22-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TOLA_RS08785 595708b5ddb679a4a973674bbf8f3568 65 SUPERFAMILY SSF143034 2 64 5.36E-24 T 22-04-2016 TOLA_RS08785 595708b5ddb679a4a973674bbf8f3568 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 22-04-2016 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS08465 7b8834f9cea794c83809ca352a9f9065 182 PIRSF PIRSF006135 1 182 8.6E-57 T 22-04-2016 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148|UniPathway: UPA00148 TOLA_RS08465 7b8834f9cea794c83809ca352a9f9065 182 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 2 179 7.4E-60 T 22-04-2016 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148|UniPathway: UPA00148 TOLA_RS08465 7b8834f9cea794c83809ca352a9f9065 182 PANTHER PTHR34848 1 182 2.4E-70 T 22-04-2016 TOLA_RS08465 7b8834f9cea794c83809ca352a9f9065 182 Gene3D G3DSA:3.40.50.300 1 181 3.9E-62 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS08465 7b8834f9cea794c83809ca352a9f9065 182 SUPERFAMILY SSF52540 1 181 9.58E-53 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12300 57cbd2d669d280886b050c91062682d0 275 Pfam PF06067 Domain of unknown function (DUF932) 37 264 3.4E-60 T 22-04-2016 IPR026325 Protein of unknown function DUF932 TOLA_RS11060 5b25c8aac313b39ce035da4de490e34c 251 Pfam PF03741 Integral membrane protein TerC family 16 204 1.7E-54 T 22-04-2016 IPR005496 Integral membrane protein TerC GO:0016021 TOLA_RS11060 5b25c8aac313b39ce035da4de490e34c 251 PANTHER PTHR30060:SF1 1 234 4.7E-119 T 22-04-2016 TOLA_RS11060 5b25c8aac313b39ce035da4de490e34c 251 PANTHER PTHR30060 1 234 4.7E-119 T 22-04-2016 TOLA_RS08015 fc06ea5ad59d8ae8e5067534d1dc1efa 404 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 359 2.6E-29 T 22-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal TOLA_RS08015 fc06ea5ad59d8ae8e5067534d1dc1efa 404 SUPERFAMILY SSF53901 1 251 2.07E-61 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS08015 fc06ea5ad59d8ae8e5067534d1dc1efa 404 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 244 1.9E-40 T 22-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal TOLA_RS08015 fc06ea5ad59d8ae8e5067534d1dc1efa 404 Gene3D G3DSA:3.40.47.10 261 403 4.1E-50 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS08015 fc06ea5ad59d8ae8e5067534d1dc1efa 404 Gene3D G3DSA:3.40.47.10 6 257 6.7E-58 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS08015 fc06ea5ad59d8ae8e5067534d1dc1efa 404 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 22-04-2016 IPR018201 Beta-ketoacyl synthase, active site TOLA_RS08015 fc06ea5ad59d8ae8e5067534d1dc1efa 404 SMART SM00825 Beta-ketoacyl synthase 4 404 7.5E-13 T 22-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TOLA_RS08015 fc06ea5ad59d8ae8e5067534d1dc1efa 404 SUPERFAMILY SSF53901 213 402 1.11E-60 T 22-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TOLA_RS08015 fc06ea5ad59d8ae8e5067534d1dc1efa 404 PANTHER PTHR11712 1 403 4.5E-168 T 22-04-2016 TOLA_RS12345 a9aaa471cbe7fe501f7ef38eeee9f249 604 PANTHER PTHR11070 20 595 1.2E-68 T 22-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 TOLA_RS12345 a9aaa471cbe7fe501f7ef38eeee9f249 604 Gene3D G3DSA:3.40.50.300 513 598 1.6E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12345 a9aaa471cbe7fe501f7ef38eeee9f249 604 Gene3D G3DSA:3.40.50.300 286 396 1.6E-28 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12345 a9aaa471cbe7fe501f7ef38eeee9f249 604 Pfam PF00580 UvrD/REP helicase N-terminal domain 20 107 8.7E-12 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TOLA_RS12345 a9aaa471cbe7fe501f7ef38eeee9f249 604 Pfam PF00580 UvrD/REP helicase N-terminal domain 170 274 1.0E-19 T 22-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TOLA_RS12345 a9aaa471cbe7fe501f7ef38eeee9f249 604 Pfam PF13361 UvrD-like helicase C-terminal domain 445 574 4.5E-19 T 22-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TOLA_RS12345 a9aaa471cbe7fe501f7ef38eeee9f249 604 SUPERFAMILY SSF52540 20 595 5.57E-84 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12345 a9aaa471cbe7fe501f7ef38eeee9f249 604 Gene3D G3DSA:3.40.50.300 24 274 2.7E-46 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12035 e85f52c283674175d98aad0ba12a2bb1 789 Pfam PF03968 OstA-like protein 67 200 1.8E-14 T 22-04-2016 IPR005653 Organic solvent tolerance-like, N-terminal TOLA_RS12035 e85f52c283674175d98aad0ba12a2bb1 789 Pfam PF04453 Organic solvent tolerance protein 313 700 8.6E-84 T 22-04-2016 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 TOLA_RS12035 e85f52c283674175d98aad0ba12a2bb1 789 PANTHER PTHR30189 65 761 5.2E-73 T 22-04-2016 TOLA_RS12035 e85f52c283674175d98aad0ba12a2bb1 789 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 6 765 20.303 T 22-04-2016 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 TOLA_RS12035 e85f52c283674175d98aad0ba12a2bb1 789 Gene3D G3DSA:2.60.450.10 61 208 4.9E-13 T 22-04-2016 TOLA_RS15580 fd04c7bb8d3a8104f2d048659cfa72dc 160 Pfam PF11848 Domain of unknown function (DUF3368) 112 152 1.5E-6 T 22-04-2016 IPR021799 Protein of unknown function DUF3368 TOLA_RS15580 fd04c7bb8d3a8104f2d048659cfa72dc 160 SUPERFAMILY SSF88723 2 120 3.36E-9 T 22-04-2016 IPR029060 PIN domain-like TOLA_RS05515 359ad49a9ec6815c61ebcfc8d97bbc27 66 Pfam PF02597 ThiS family 4 66 1.5E-10 T 22-04-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 TOLA_RS05515 359ad49a9ec6815c61ebcfc8d97bbc27 66 Gene3D G3DSA:3.10.20.30 1 66 2.9E-21 T 22-04-2016 IPR012675 Beta-grasp domain TOLA_RS05515 359ad49a9ec6815c61ebcfc8d97bbc27 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 3.2E-18 T 22-04-2016 IPR010035 ThiS, thiamine-biosynthesis TOLA_RS05515 359ad49a9ec6815c61ebcfc8d97bbc27 66 PANTHER PTHR34472 1 66 1.1E-21 T 22-04-2016 TOLA_RS05515 359ad49a9ec6815c61ebcfc8d97bbc27 66 SUPERFAMILY SSF54285 1 66 2.33E-15 T 22-04-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TOLA_RS05515 359ad49a9ec6815c61ebcfc8d97bbc27 66 PANTHER PTHR34472:SF1 1 66 1.1E-21 T 22-04-2016 TOLA_RS02365 ed6055b98bbb1b7a10e1c2c68cea1234 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 6.2E-19 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS02365 ed6055b98bbb1b7a10e1c2c68cea1234 328 Gene3D G3DSA:3.40.50.2300 170 302 5.6E-23 T 22-04-2016 TOLA_RS02365 ed6055b98bbb1b7a10e1c2c68cea1234 328 SUPERFAMILY SSF53822 61 325 8.34E-37 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS02365 ed6055b98bbb1b7a10e1c2c68cea1234 328 SUPERFAMILY SSF47413 1 59 7.16E-17 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS02365 ed6055b98bbb1b7a10e1c2c68cea1234 328 PANTHER PTHR30146:SF48 1 325 1.0E-65 T 22-04-2016 TOLA_RS02365 ed6055b98bbb1b7a10e1c2c68cea1234 328 Gene3D G3DSA:1.10.260.40 2 53 5.4E-24 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS02365 ed6055b98bbb1b7a10e1c2c68cea1234 328 Gene3D G3DSA:3.40.50.2300 54 169 2.6E-24 T 22-04-2016 TOLA_RS02365 ed6055b98bbb1b7a10e1c2c68cea1234 328 PANTHER PTHR30146 1 325 1.0E-65 T 22-04-2016 TOLA_RS02365 ed6055b98bbb1b7a10e1c2c68cea1234 328 Pfam PF13377 Periplasmic binding protein-like domain 168 324 2.2E-21 T 22-04-2016 TOLA_RS02365 ed6055b98bbb1b7a10e1c2c68cea1234 328 SMART SM00354 1 71 7.1E-31 T 22-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 TOLA_RS09645 66dcfff4bb90d30691c94dd40556dd3a 115 SUPERFAMILY SSF52794 7 102 1.92E-30 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS09645 66dcfff4bb90d30691c94dd40556dd3a 115 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 8 89 3.6E-29 T 22-04-2016 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 TOLA_RS09645 66dcfff4bb90d30691c94dd40556dd3a 115 PANTHER PTHR30505 7 104 6.5E-41 T 22-04-2016 TOLA_RS09645 66dcfff4bb90d30691c94dd40556dd3a 115 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 9 99 6.9E-16 T 22-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 TOLA_RS09645 66dcfff4bb90d30691c94dd40556dd3a 115 Gene3D G3DSA:3.40.50.2300 5 102 5.3E-35 T 22-04-2016 TOLA_RS04015 882df317b9b1a38f8db0ec46a2396372 503 Pfam PF14400 Inactive transglutaminase fused to 7 transmembrane helices 24 180 9.4E-51 T 22-04-2016 IPR025838 Inactive transglutaminase fused to 7 transmembrane helices TOLA_RS04015 882df317b9b1a38f8db0ec46a2396372 503 Pfam PF14402 7 transmembrane helices usually fused to an inactive transglutaminase 188 496 1.8E-138 T 22-04-2016 IPR025840 7 transmembrane helices usually fused to an inactive transglutaminase TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 SUPERFAMILY SSF51735 5 247 2.59E-77 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.1E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.1E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.1E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 2.1E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.1E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.1E-48 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PANTHER PTHR24322 155 187 4.9E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PANTHER PTHR24322 10 29 4.9E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PANTHER PTHR24322 47 139 4.9E-51 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 186 2.5E-5 T 22-04-2016 TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.4E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.4E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.4E-15 T 22-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 5.5E-57 T 22-04-2016 TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 6 247 3.7E-105 T 22-04-2016 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|UniPathway: UPA00917 TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 22-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 Gene3D G3DSA:3.40.50.720 4 247 1.8E-79 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PANTHER PTHR24322:SF328 155 187 4.9E-51 T 22-04-2016 TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PANTHER PTHR24322:SF328 10 29 4.9E-51 T 22-04-2016 TOLA_RS12560 a2e29465cf14b609707ffe9cd124bce3 248 PANTHER PTHR24322:SF328 47 139 4.9E-51 T 22-04-2016 TOLA_RS04095 e4926b413edf3064bb4ce53cc9b0100a 61 Pfam PF12244 Protein of unknown function (DUF3606) 6 57 7.6E-19 T 22-04-2016 IPR022037 Protein of unknown function DUF3606 TOLA_RS08595 dc6ab0d88485c172bfbc4452980900d5 118 SUPERFAMILY SSF52968 8 117 4.32E-33 T 22-04-2016 IPR010254 B12-dependent dehydratases, beta subunit TOLA_RS08595 dc6ab0d88485c172bfbc4452980900d5 118 Gene3D G3DSA:3.40.50.10150 6 117 4.1E-37 T 22-04-2016 IPR010254 B12-dependent dehydratases, beta subunit TOLA_RS08595 dc6ab0d88485c172bfbc4452980900d5 118 PIRSF PIRSF011503 1 118 2.1E-38 T 22-04-2016 IPR009192 Diol/glycerol dehydratase reactivating factor, small subunit TOLA_RS08595 dc6ab0d88485c172bfbc4452980900d5 118 Pfam PF02288 Dehydratase medium subunit 8 116 1.4E-32 T 22-04-2016 IPR003208 Diol/glycerol dehydratase/dehydratase reactivating factor TOLA_RS10055 32d1bc7fe4c5e03a700c8b740ac15753 219 Pfam PF16161 Domain of unknown function (DUF4867) 16 213 2.8E-69 T 22-04-2016 IPR032358 Protein of unknown function DUF4867 TOLA_RS15735 99eff06fe52cb0cd8ae03b7b5c181ab7 355 Gene3D G3DSA:3.60.15.10 1 337 4.1E-120 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS15735 99eff06fe52cb0cd8ae03b7b5c181ab7 355 PANTHER PTHR15032:SF13 4 77 1.8E-135 T 22-04-2016 TOLA_RS15735 99eff06fe52cb0cd8ae03b7b5c181ab7 355 PANTHER PTHR15032:SF13 94 355 1.8E-135 T 22-04-2016 TOLA_RS15735 99eff06fe52cb0cd8ae03b7b5c181ab7 355 Pfam PF12706 Beta-lactamase superfamily domain 99 283 1.4E-11 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS15735 99eff06fe52cb0cd8ae03b7b5c181ab7 355 SUPERFAMILY SSF56281 36 290 3.52E-26 T 22-04-2016 IPR001279 Metallo-beta-lactamase TOLA_RS15735 99eff06fe52cb0cd8ae03b7b5c181ab7 355 PANTHER PTHR15032 4 77 1.8E-135 T 22-04-2016 TOLA_RS15735 99eff06fe52cb0cd8ae03b7b5c181ab7 355 PANTHER PTHR15032 94 355 1.8E-135 T 22-04-2016 TOLA_RS14780 1a212e2d81546f91196dafd5fb8ed284 433 PANTHER PTHR11662 20 433 7.2E-222 T 22-04-2016 TOLA_RS14780 1a212e2d81546f91196dafd5fb8ed284 433 Gene3D G3DSA:1.20.1250.20 233 430 2.8E-22 T 22-04-2016 TOLA_RS14780 1a212e2d81546f91196dafd5fb8ed284 433 Gene3D G3DSA:1.20.1250.20 18 212 8.5E-48 T 22-04-2016 TOLA_RS14780 1a212e2d81546f91196dafd5fb8ed284 433 Pfam PF07690 Major Facilitator Superfamily 30 390 3.5E-54 T 22-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TOLA_RS14780 1a212e2d81546f91196dafd5fb8ed284 433 SUPERFAMILY SSF103473 15 432 1.01E-77 T 22-04-2016 IPR020846 Major facilitator superfamily domain TOLA_RS14780 1a212e2d81546f91196dafd5fb8ed284 433 PANTHER PTHR11662:SF285 20 433 7.2E-222 T 22-04-2016 TOLA_RS12525 c3a2eb35f65a24196da7350a6448f1d9 347 Pfam PF13387 Domain of unknown function (DUF4105) 131 285 9.6E-47 T 22-04-2016 IPR025178 Domain of unknown function DUF4105 TOLA_RS03945 0bbbab12c0687bb991763fb98a02238d 160 PANTHER PTHR36926:SF1 1 159 1.2E-74 T 22-04-2016 TOLA_RS03945 0bbbab12c0687bb991763fb98a02238d 160 PANTHER PTHR36926 1 159 1.2E-74 T 22-04-2016 TOLA_RS03945 0bbbab12c0687bb991763fb98a02238d 160 Pfam PF02674 Colicin V production protein 4 141 6.8E-34 T 22-04-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 TOLA_RS06225 e322cf9c18dfde4044941fb60d9d3d64 109 SUPERFAMILY SSF69721 2 109 2.35E-41 T 22-04-2016 IPR025526 DsrC-like domain TOLA_RS06225 e322cf9c18dfde4044941fb60d9d3d64 109 PANTHER PTHR37010:SF1 1 109 8.3E-56 T 22-04-2016 TOLA_RS06225 e322cf9c18dfde4044941fb60d9d3d64 109 Pfam PF04358 DsrC like protein 5 109 5.2E-45 T 22-04-2016 IPR007453 Sulphur transfer protein DsrC/TusE TOLA_RS06225 e322cf9c18dfde4044941fb60d9d3d64 109 PIRSF PIRSF006223 2 109 3.5E-44 T 22-04-2016 IPR007453 Sulphur transfer protein DsrC/TusE TOLA_RS06225 e322cf9c18dfde4044941fb60d9d3d64 109 Gene3D G3DSA:3.30.1420.10 3 39 6.1E-13 T 22-04-2016 TOLA_RS06225 e322cf9c18dfde4044941fb60d9d3d64 109 PANTHER PTHR37010 1 109 8.3E-56 T 22-04-2016 TOLA_RS06225 e322cf9c18dfde4044941fb60d9d3d64 109 Gene3D G3DSA:1.10.10.370 40 109 3.9E-37 T 22-04-2016 TOLA_RS06225 e322cf9c18dfde4044941fb60d9d3d64 109 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 4 109 1.4E-49 T 22-04-2016 IPR007453 Sulphur transfer protein DsrC/TusE TOLA_RS11155 099a980140f8a4130f07a6727a979578 173 PANTHER PTHR38099 2 173 1.0E-57 T 22-04-2016 TOLA_RS11155 099a980140f8a4130f07a6727a979578 173 Pfam PF02620 Uncharacterized ACR, COG1399 61 171 1.6E-16 T 22-04-2016 IPR003772 Protein of unknown function DUF177 TOLA_RS13890 e2cf29023019e47a808762ef6a99f07a 226 PANTHER PTHR18901 1 220 1.3E-52 T 22-04-2016 TOLA_RS13890 e2cf29023019e47a808762ef6a99f07a 226 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 141 192 3.0E-10 T 22-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TOLA_RS13890 e2cf29023019e47a808762ef6a99f07a 226 Gene3D G3DSA:3.40.50.1000 1 18 9.4E-30 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13890 e2cf29023019e47a808762ef6a99f07a 226 Gene3D G3DSA:3.40.50.1000 95 219 9.4E-30 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13890 e2cf29023019e47a808762ef6a99f07a 226 Gene3D G3DSA:1.10.150.240 19 83 2.3E-6 T 22-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 TOLA_RS13890 e2cf29023019e47a808762ef6a99f07a 226 SUPERFAMILY SSF56784 1 219 6.75E-35 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13890 e2cf29023019e47a808762ef6a99f07a 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 191 1.6E-14 T 22-04-2016 IPR023214 HAD-like domain TOLA_RS13890 e2cf29023019e47a808762ef6a99f07a 226 PANTHER PTHR18901:SF10 1 220 1.3E-52 T 22-04-2016 TOLA_RS01085 f7ba2b5c7542252c747fee35ef3cbdea 431 Pfam PF00498 FHA domain 29 97 2.7E-12 T 22-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TOLA_RS01085 f7ba2b5c7542252c747fee35ef3cbdea 431 Gene3D G3DSA:2.60.200.20 15 110 5.0E-16 T 22-04-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TOLA_RS01085 f7ba2b5c7542252c747fee35ef3cbdea 431 SUPERFAMILY SSF49879 19 106 8.42E-17 T 22-04-2016 IPR008984 SMAD/FHA domain GO:0005515 TOLA_RS01085 f7ba2b5c7542252c747fee35ef3cbdea 431 TIGRFAM TIGR03354 VI_FHA: type VI secretion system FHA domain protein 3 418 1.5E-83 T 22-04-2016 IPR017735 Type VI secretion system, FHA domain-containing protein TOLA_RS02965 6d1c75db1fd323f898e7f5fad7b97603 295 SUPERFAMILY SSF53822 12 295 9.57E-86 T 22-04-2016 IPR028082 Periplasmic binding protein-like I TOLA_RS02965 6d1c75db1fd323f898e7f5fad7b97603 295 Pfam PF13407 Periplasmic binding protein domain 30 280 1.0E-56 T 22-04-2016 IPR025997 Periplasmic binding protein TOLA_RS02965 6d1c75db1fd323f898e7f5fad7b97603 295 PANTHER PTHR32196 15 293 3.9E-110 T 22-04-2016 TOLA_RS02965 6d1c75db1fd323f898e7f5fad7b97603 295 PANTHER PTHR32196:SF9 15 293 3.9E-110 T 22-04-2016 TOLA_RS02965 6d1c75db1fd323f898e7f5fad7b97603 295 Gene3D G3DSA:3.40.50.2300 27 144 3.6E-44 T 22-04-2016 TOLA_RS02965 6d1c75db1fd323f898e7f5fad7b97603 295 Gene3D G3DSA:3.40.50.2300 145 295 1.1E-53 T 22-04-2016 TOLA_RS02175 fc6a5f620824728c8ddd5fed32fba388 540 SUPERFAMILY SSF53795 228 539 7.51E-127 T 22-04-2016 TOLA_RS02175 fc6a5f620824728c8ddd5fed32fba388 540 PIRSF PIRSF006294 2 539 7.5E-226 T 22-04-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 TOLA_RS02175 fc6a5f620824728c8ddd5fed32fba388 540 SUPERFAMILY SSF68923 9 226 1.19E-87 T 22-04-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS02175 fc6a5f620824728c8ddd5fed32fba388 540 Gene3D G3DSA:3.90.228.20 350 538 4.9E-119 T 22-04-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS02175 fc6a5f620824728c8ddd5fed32fba388 540 Gene3D G3DSA:3.90.228.20 227 289 4.9E-119 T 22-04-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS02175 fc6a5f620824728c8ddd5fed32fba388 540 PANTHER PTHR30031:SF0 15 540 0.0 T 22-04-2016 TOLA_RS02175 fc6a5f620824728c8ddd5fed32fba388 540 PANTHER PTHR30031 15 540 0.0 T 22-04-2016 TOLA_RS02175 fc6a5f620824728c8ddd5fed32fba388 540 Gene3D G3DSA:3.40.449.10 21 225 9.5E-85 T 22-04-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 TOLA_RS02175 fc6a5f620824728c8ddd5fed32fba388 540 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 264 279 - T 22-04-2016 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 TOLA_RS02175 fc6a5f620824728c8ddd5fed32fba388 540 Hamap MF_00453 Phosphoenolpyruvate carboxykinase [ATP] [pckA]. 15 537 54.295 T 22-04-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 TOLA_RS02175 fc6a5f620824728c8ddd5fed32fba388 540 Pfam PF01293 Phosphoenolpyruvate carboxykinase 21 490 6.7E-208 T 22-04-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 TOLA_RS02175 fc6a5f620824728c8ddd5fed32fba388 540 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 6 539 1.0E-271 T 22-04-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 TOLA_RS06890 52148eb1d17f804f8e421416c95a5cc7 207 PANTHER PTHR36698:SF1 1 196 1.5E-28 T 22-04-2016 TOLA_RS06890 52148eb1d17f804f8e421416c95a5cc7 207 PANTHER PTHR36698 1 196 1.5E-28 T 22-04-2016 TOLA_RS06890 52148eb1d17f804f8e421416c95a5cc7 207 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 32 192 2.8E-20 T 22-04-2016 IPR005586 ABC-type transport auxiliary lipoprotein component TOLA_RS06890 52148eb1d17f804f8e421416c95a5cc7 207 SUPERFAMILY SSF159594 29 198 7.85E-41 T 22-04-2016 TOLA_RS06890 52148eb1d17f804f8e421416c95a5cc7 207 Gene3D G3DSA:3.40.50.10610 20 200 8.9E-54 T 22-04-2016 IPR005586 ABC-type transport auxiliary lipoprotein component TOLA_RS04255 670ca90f0889a8025ac630afd5cbf257 125 Pfam PF16358 RcsF lipoprotein 34 121 6.6E-14 T 22-04-2016 IPR030852 Outer membrane lipoprotein RcsF GO:0009279|GO:0035556 TOLA_RS06725 2701053aff6e208662d33c5fcba76e10 751 Pfam PF05170 AsmA family 1 633 1.7E-51 T 22-04-2016 IPR007844 AsmA TOLA_RS06725 2701053aff6e208662d33c5fcba76e10 751 PANTHER PTHR30441:SF4 1 747 2.5E-54 T 22-04-2016 TOLA_RS06725 2701053aff6e208662d33c5fcba76e10 751 PANTHER PTHR30441 1 747 2.5E-54 T 22-04-2016 TOLA_RS01835 d3d5f2679ca75a2579e063c319f5f058 661 Gene3D G3DSA:3.30.2010.10 102 185 8.5E-24 T 22-04-2016 TOLA_RS01835 d3d5f2679ca75a2579e063c319f5f058 661 Pfam PF01435 Peptidase family M48 107 328 7.3E-28 T 22-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TOLA_RS01835 d3d5f2679ca75a2579e063c319f5f058 661 PANTHER PTHR10120 313 349 1.7E-43 T 22-04-2016 TOLA_RS01835 d3d5f2679ca75a2579e063c319f5f058 661 PANTHER PTHR10120 108 297 1.7E-43 T 22-04-2016 TOLA_RS01835 d3d5f2679ca75a2579e063c319f5f058 661 PANTHER PTHR10120:SF19 313 349 1.7E-43 T 22-04-2016 TOLA_RS01835 d3d5f2679ca75a2579e063c319f5f058 661 PANTHER PTHR10120:SF19 108 297 1.7E-43 T 22-04-2016 TOLA_RS01815 4dc411ac4881c343d8539fdb220f7b86 194 SUPERFAMILY SSF81342 6 191 3.92E-31 T 22-04-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 TOLA_RS01815 4dc411ac4881c343d8539fdb220f7b86 194 Pfam PF01292 Prokaryotic cytochrome b561 11 188 3.9E-18 T 22-04-2016 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 TOLA_RS01815 4dc411ac4881c343d8539fdb220f7b86 194 Gene3D G3DSA:1.20.950.20 5 191 1.0E-8 T 22-04-2016 TOLA_RS06220 93e291aca82763e6f94c500953ccfb5b 350 Gene3D G3DSA:2.30.27.10 25 81 7.5E-5 T 22-04-2016 TOLA_RS12640 4f33b4ae921857ec46381d8ca15b16c3 644 Pfam PF00589 Phage integrase family 216 392 3.2E-17 T 22-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS12640 4f33b4ae921857ec46381d8ca15b16c3 644 Gene3D G3DSA:1.10.443.10 215 395 2.3E-19 T 22-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TOLA_RS12640 4f33b4ae921857ec46381d8ca15b16c3 644 Gene3D G3DSA:1.10.150.130 100 198 1.0E-12 T 22-04-2016 IPR023109 Integrase/recombinase, N-terminal TOLA_RS12640 4f33b4ae921857ec46381d8ca15b16c3 644 SUPERFAMILY SSF56349 100 402 3.53E-50 T 22-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TOLA_RS12640 4f33b4ae921857ec46381d8ca15b16c3 644 Pfam PF13356 Domain of unknown function (DUF4102) 7 88 1.1E-16 T 22-04-2016 IPR025166 Domain of unknown function DUF4102 TOLA_RS12640 4f33b4ae921857ec46381d8ca15b16c3 644 PANTHER PTHR30629:SF4 1 435 3.7E-176 T 22-04-2016 TOLA_RS12640 4f33b4ae921857ec46381d8ca15b16c3 644 PANTHER PTHR30629 1 435 3.7E-176 T 22-04-2016 TOLA_RS13545 c26edecbf744d65a87769af3c01a3ee8 235 Pfam PF16537 Type II secretion system protein B 169 228 4.2E-22 T 22-04-2016 IPR032389 Type II secretion system protein B TOLA_RS06175 62f6321fa744c0d9ca6a854a4d7ff059 147 Gene3D G3DSA:3.10.129.10 8 137 2.1E-33 T 22-04-2016 IPR029069 HotDog domain TOLA_RS06175 62f6321fa744c0d9ca6a854a4d7ff059 147 PANTHER PTHR12418 30 137 9.2E-13 T 22-04-2016 TOLA_RS06175 62f6321fa744c0d9ca6a854a4d7ff059 147 Pfam PF03061 Thioesterase superfamily 55 110 2.8E-8 T 22-04-2016 IPR006683 Thioesterase domain TOLA_RS06175 62f6321fa744c0d9ca6a854a4d7ff059 147 PANTHER PTHR12418:SF16 30 137 9.2E-13 T 22-04-2016 TOLA_RS06175 62f6321fa744c0d9ca6a854a4d7ff059 147 SUPERFAMILY SSF54637 8 135 4.93E-30 T 22-04-2016 IPR029069 HotDog domain TOLA_RS06175 62f6321fa744c0d9ca6a854a4d7ff059 147 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 27 108 1.1E-11 T 22-04-2016 IPR003736 Phenylacetic acid degradation-related domain TOLA_RS09910 8c44631d7e87eb1e08f93bda57568627 205 Pfam PF14559 Tetratricopeptide repeat 132 180 1.1E-5 T 22-04-2016 TOLA_RS09910 8c44631d7e87eb1e08f93bda57568627 205 SUPERFAMILY SSF48452 61 176 4.55E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS09910 8c44631d7e87eb1e08f93bda57568627 205 Gene3D G3DSA:1.25.40.10 91 180 5.2E-13 T 22-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TOLA_RS12440 a9604e0a28299667131795373ae75bbd 234 Pfam PF13462 Thioredoxin 44 190 3.9E-11 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS12440 a9604e0a28299667131795373ae75bbd 234 SUPERFAMILY SSF52833 15 207 3.49E-26 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS12440 a9604e0a28299667131795373ae75bbd 234 Gene3D G3DSA:3.40.30.10 44 211 1.0E-24 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS04345 d6f730fa9fcd6e0106c0cd98b41c3e26 153 PANTHER PTHR35867:SF1 2 146 1.4E-29 T 22-04-2016 TOLA_RS04345 d6f730fa9fcd6e0106c0cd98b41c3e26 153 PANTHER PTHR35867 2 146 1.4E-29 T 22-04-2016 TOLA_RS04345 d6f730fa9fcd6e0106c0cd98b41c3e26 153 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 8 141 1.9E-34 T 22-04-2016 IPR007359 Positive regulator of sigma(E), RseC/MucC TOLA_RS04345 d6f730fa9fcd6e0106c0cd98b41c3e26 153 PIRSF PIRSF004923 1 151 6.2E-36 T 22-04-2016 IPR026268 Protein RseC TOLA_RS12340 a5cf809f257b26f4dafb14cd9ee41b67 256 Pfam PF06054 Competence protein CoiA-like family 36 154 5.3E-8 T 22-04-2016 IPR010330 Competence-induced protein CoiA-like TOLA_RS07540 c939bcb9ffa7ca84f2ee140033f39245 214 PANTHER PTHR22939:SF104 34 200 1.3E-39 T 22-04-2016 TOLA_RS07540 c939bcb9ffa7ca84f2ee140033f39245 214 Pfam PF02163 Peptidase family M50 119 170 9.2E-9 T 22-04-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 TOLA_RS07540 c939bcb9ffa7ca84f2ee140033f39245 214 PANTHER PTHR22939 34 200 1.3E-39 T 22-04-2016 TOLA_RS16030 ba946c979968e58310367923d54a3b4d 94 Gene3D G3DSA:3.40.30.10 2 92 4.2E-44 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS16030 ba946c979968e58310367923d54a3b4d 94 Pfam PF10262 Rdx family 6 78 4.3E-32 T 22-04-2016 IPR011893 Selenoprotein, Rdx type TOLA_RS16030 ba946c979968e58310367923d54a3b4d 94 PANTHER PTHR36417 1 91 2.2E-49 T 22-04-2016 TOLA_RS16030 ba946c979968e58310367923d54a3b4d 94 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 6 77 3.5E-22 T 22-04-2016 IPR011893 Selenoprotein, Rdx type TOLA_RS16030 ba946c979968e58310367923d54a3b4d 94 PANTHER PTHR36417:SF1 1 91 2.2E-49 T 22-04-2016 TOLA_RS16030 ba946c979968e58310367923d54a3b4d 94 SUPERFAMILY SSF52833 4 87 2.08E-29 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS01840 dbf02372636cdcafcbf154b389667a1d 198 Pfam PF04011 LemA family 7 198 3.7E-63 T 22-04-2016 IPR007156 LemA TOLA_RS01840 dbf02372636cdcafcbf154b389667a1d 198 PANTHER PTHR34478 1 198 1.4E-68 T 22-04-2016 TOLA_RS01840 dbf02372636cdcafcbf154b389667a1d 198 Gene3D G3DSA:1.20.1440.20 15 198 4.6E-61 T 22-04-2016 IPR023353 LemA-like domain TOLA_RS01840 dbf02372636cdcafcbf154b389667a1d 198 SUPERFAMILY SSF140478 26 176 1.96E-51 T 22-04-2016 IPR023353 LemA-like domain TOLA_RS16400 b83e3bec6050f1208599d9659ed84b48 715 Pfam PF06082 Exopolysaccharide biosynthesis protein YbjH 34 159 1.7E-12 T 22-04-2016 IPR010344 Exopolysaccharide biosynthesis protein YbjH TOLA_RS16400 b83e3bec6050f1208599d9659ed84b48 715 Pfam PF06082 Exopolysaccharide biosynthesis protein YbjH 169 546 3.5E-15 T 22-04-2016 IPR010344 Exopolysaccharide biosynthesis protein YbjH TOLA_RS01850 a40a211883f925a041ad2e0d0cf9f281 622 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 5 622 33.466 T 22-04-2016 IPR023051 Potassium uptake protein, low affinity, Kup TOLA_RS01850 a40a211883f925a041ad2e0d0cf9f281 622 PANTHER PTHR30540 16 548 3.8E-242 T 22-04-2016 TOLA_RS01850 a40a211883f925a041ad2e0d0cf9f281 622 Pfam PF02705 K+ potassium transporter 14 544 5.0E-208 T 22-04-2016 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 TOLA_RS01850 a40a211883f925a041ad2e0d0cf9f281 622 PANTHER PTHR30540:SF7 16 548 3.8E-242 T 22-04-2016 TOLA_RS06955 9330b0b00f31763de58fc47d4cfd1e01 339 TIGRFAM TIGR02566 cas_Csy3: CRISPR type I-F/YPEST-associated protein Csy3 7 338 8.0E-139 T 22-04-2016 IPR013399 CRISPR-associated protein Csy3 TOLA_RS06955 9330b0b00f31763de58fc47d4cfd1e01 339 Pfam PF09615 CRISPR-associated protein (Cas_Csy3) 8 336 6.4E-149 T 22-04-2016 IPR013399 CRISPR-associated protein Csy3 TOLA_RS13350 73ebf3d6ae7960bd818d5b62ba62b7c8 181 PIRSF PIRSF016481 1 173 2.2E-48 T 22-04-2016 IPR007446 Pilus assembly protein PilP TOLA_RS13350 73ebf3d6ae7960bd818d5b62ba62b7c8 181 Pfam PF04351 Pilus assembly protein, PilP 23 169 4.9E-51 T 22-04-2016 IPR007446 Pilus assembly protein PilP TOLA_RS04105 0148726aa8bc86ea2b8d66801c78d474 345 Pfam PF02424 ApbE family 36 319 2.2E-79 T 22-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 TOLA_RS04105 0148726aa8bc86ea2b8d66801c78d474 345 PANTHER PTHR30040:SF3 6 344 6.3E-145 T 22-04-2016 TOLA_RS04105 0148726aa8bc86ea2b8d66801c78d474 345 PANTHER PTHR30040 6 344 6.3E-145 T 22-04-2016 TOLA_RS04105 0148726aa8bc86ea2b8d66801c78d474 345 PIRSF PIRSF006268 1 340 1.2E-89 T 22-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 TOLA_RS04105 0148726aa8bc86ea2b8d66801c78d474 345 SUPERFAMILY SSF143631 28 340 3.92E-92 T 22-04-2016 IPR003374 ApbE-like domain TOLA_RS08030 20c26856c743ed00083e53121f3cd7d1 79 Pfam PF10982 Protein of unknown function (DUF2789) 1 74 3.8E-26 T 22-04-2016 IPR021250 Protein of unknown function DUF2789 TOLA_RS07415 a105b2b2c4afe0d27e87ac72ade64aea 83 Gene3D G3DSA:1.10.720.30 14 70 1.1E-32 T 22-04-2016 IPR003034 SAP domain TOLA_RS07415 a105b2b2c4afe0d27e87ac72ade64aea 83 Pfam PF09905 Uncharacterized conserved protein (DUF2132) 7 68 5.3E-36 T 22-04-2016 IPR018668 DNA-binding protein VF530-like, bacteria GO:0003677 TOLA_RS12320 6d5464d4a634d8bc885b5d710941e54d 369 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 41 55 3.3E-8 T 22-04-2016 TOLA_RS12320 6d5464d4a634d8bc885b5d710941e54d 369 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 101 113 3.3E-8 T 22-04-2016 TOLA_RS12320 6d5464d4a634d8bc885b5d710941e54d 369 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 130 154 3.3E-8 T 22-04-2016 TOLA_RS12320 6d5464d4a634d8bc885b5d710941e54d 369 SUPERFAMILY SSF53335 18 199 2.76E-24 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS12320 6d5464d4a634d8bc885b5d710941e54d 369 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 104 110 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TOLA_RS12320 6d5464d4a634d8bc885b5d710941e54d 369 Gene3D G3DSA:3.40.50.150 35 191 1.9E-22 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS11490 33679470b7b531934d2c083b56ba5877 85 PANTHER PTHR37483:SF1 2 80 3.5E-26 T 22-04-2016 TOLA_RS11490 33679470b7b531934d2c083b56ba5877 85 PANTHER PTHR37483 2 80 3.5E-26 T 22-04-2016 TOLA_RS11490 33679470b7b531934d2c083b56ba5877 85 Gene3D G3DSA:3.10.20.280 2 75 1.8E-26 T 22-04-2016 IPR005346 RnfH protein TOLA_RS11490 33679470b7b531934d2c083b56ba5877 85 Pfam PF03658 RnfH family Ubiquitin 2 73 7.3E-26 T 22-04-2016 IPR005346 RnfH protein TOLA_RS11490 33679470b7b531934d2c083b56ba5877 85 Hamap MF_00460 Protein RnfH [rnfH]. 1 81 16.591 T 22-04-2016 IPR005346 RnfH protein TOLA_RS11490 33679470b7b531934d2c083b56ba5877 85 SUPERFAMILY SSF54285 2 65 1.57E-16 T 22-04-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TOLA_RS14230 96c0651f0b7339cb7638f06e1ace3972 118 TIGRFAM TIGR03010 sulf_tusC_dsrF: sulfur relay protein TusC/DsrF 3 116 1.4E-38 T 22-04-2016 IPR017462 Sulphur relay, TusC/DsrF TOLA_RS14230 96c0651f0b7339cb7638f06e1ace3972 118 PANTHER PTHR38780 1 118 7.7E-38 T 22-04-2016 TOLA_RS14230 96c0651f0b7339cb7638f06e1ace3972 118 Pfam PF02635 DsrE/DsrF-like family 3 110 5.0E-19 T 22-04-2016 IPR003787 Sulphur relay, DsrE/F-like protein TOLA_RS14230 96c0651f0b7339cb7638f06e1ace3972 118 PANTHER PTHR38780:SF1 1 118 7.7E-38 T 22-04-2016 TOLA_RS14230 96c0651f0b7339cb7638f06e1ace3972 118 SUPERFAMILY SSF75169 1 118 4.04E-30 T 22-04-2016 IPR027396 DsrEFH-like TOLA_RS14230 96c0651f0b7339cb7638f06e1ace3972 118 Gene3D G3DSA:3.40.1260.10 1 118 2.9E-39 T 22-04-2016 IPR027396 DsrEFH-like TOLA_RS01070 fe502fa6024b7509cb75b4cc95563cdf 339 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 21 320 1.3E-78 T 22-04-2016 IPR010732 Type VI secretion, TssG-like TOLA_RS01070 fe502fa6024b7509cb75b4cc95563cdf 339 PANTHER PTHR35564 18 326 9.3E-90 T 22-04-2016 TOLA_RS01070 fe502fa6024b7509cb75b4cc95563cdf 339 Pfam PF06996 Type VI secretion, VasB, ImpH, VC_A0111 22 321 4.8E-79 T 22-04-2016 IPR010732 Type VI secretion, TssG-like TOLA_RS01070 fe502fa6024b7509cb75b4cc95563cdf 339 PANTHER PTHR35564:SF3 18 326 9.3E-90 T 22-04-2016 TOLA_RS15540 61c6fd2786aaf61af8c289c12e757e5c 495 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 108 494 5.7E-158 T 22-04-2016 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 TOLA_RS15540 61c6fd2786aaf61af8c289c12e757e5c 495 SMART SM00858 11 82 2.0E-15 T 22-04-2016 IPR013974 SAF domain TOLA_RS15540 61c6fd2786aaf61af8c289c12e757e5c 495 Pfam PF08666 SAF domain 11 81 1.1E-11 T 22-04-2016 IPR013974 SAF domain TOLA_RS15540 61c6fd2786aaf61af8c289c12e757e5c 495 PANTHER PTHR30536:SF5 1 495 8.6E-260 T 22-04-2016 TOLA_RS15540 61c6fd2786aaf61af8c289c12e757e5c 495 PANTHER PTHR30536 1 495 8.6E-260 T 22-04-2016 TOLA_RS05855 177bc6c5a532aff0a08726b9c78dd38e 216 Pfam PF04970 Lecithin retinol acyltransferase 2 100 9.1E-19 T 22-04-2016 IPR007053 LRAT-like domain TOLA_RS06480 e56aa9859a1ae0ee5d37b6368189ddc7 197 PANTHER PTHR21327 1 195 1.3E-125 T 22-04-2016 TOLA_RS06480 e56aa9859a1ae0ee5d37b6368189ddc7 197 PANTHER PTHR21327:SF14 1 195 1.3E-125 T 22-04-2016 TOLA_RS06480 e56aa9859a1ae0ee5d37b6368189ddc7 197 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 7 195 6.6E-86 T 22-04-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 TOLA_RS06480 e56aa9859a1ae0ee5d37b6368189ddc7 197 SUPERFAMILY SSF142695 3 173 2.48E-67 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 TOLA_RS06480 e56aa9859a1ae0ee5d37b6368189ddc7 197 Pfam PF00925 GTP cyclohydrolase II 7 171 4.6E-70 T 22-04-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 TOLA_RS06480 e56aa9859a1ae0ee5d37b6368189ddc7 197 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 2 197 45.195 T 22-04-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 TOLA_RS05165 e93cb8f0fa0db1feb79029eba17dfca0 127 Pfam PF10865 Domain of unknown function (DUF2703) 4 119 3.7E-37 T 22-04-2016 IPR021219 Protein of unknown function DUF2703 TOLA_RS04990 3e21c9981768872a5cd4ac07e42bac86 237 Pfam PF05175 Methyltransferase small domain 34 158 1.5E-16 T 22-04-2016 IPR007848 Methyltransferase small domain GO:0008168 TOLA_RS04990 3e21c9981768872a5cd4ac07e42bac86 237 PANTHER PTHR18895 25 225 1.3E-71 T 22-04-2016 TOLA_RS04990 3e21c9981768872a5cd4ac07e42bac86 237 SUPERFAMILY SSF53335 6 182 1.66E-33 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04990 3e21c9981768872a5cd4ac07e42bac86 237 PANTHER PTHR18895:SF73 25 225 1.3E-71 T 22-04-2016 TOLA_RS04990 3e21c9981768872a5cd4ac07e42bac86 237 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 109 115 - T 22-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TOLA_RS04990 3e21c9981768872a5cd4ac07e42bac86 237 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 136 160 4.3E-6 T 22-04-2016 TOLA_RS04990 3e21c9981768872a5cd4ac07e42bac86 237 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 41 55 4.3E-6 T 22-04-2016 TOLA_RS04990 3e21c9981768872a5cd4ac07e42bac86 237 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 106 118 4.3E-6 T 22-04-2016 TOLA_RS04990 3e21c9981768872a5cd4ac07e42bac86 237 Gene3D G3DSA:3.40.50.150 25 227 3.1E-46 T 22-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TOLA_RS04990 3e21c9981768872a5cd4ac07e42bac86 237 Hamap MF_01872 tRNA1(Val) (adenine(37)-N6)-methyltransferase [yfiC]. 4 235 57.153 T 22-04-2016 IPR022882 tRNA1(Val) (adenine(37)-N6)-methyltransferase GO:0016430 KEGG: 00340+2.1.1.22 TOLA_RS06475 e3c1c60988f7268d809b5c2e4b152259 1368 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1254 1272 - T 22-04-2016 IPR018511 Hemolysin-type calcium-binding conserved site TOLA_RS06475 e3c1c60988f7268d809b5c2e4b152259 1368 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1236 1254 - T 22-04-2016 IPR018511 Hemolysin-type calcium-binding conserved site TOLA_RS06475 e3c1c60988f7268d809b5c2e4b152259 1368 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1227 1245 - T 22-04-2016 IPR018511 Hemolysin-type calcium-binding conserved site TOLA_RS06475 e3c1c60988f7268d809b5c2e4b152259 1368 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 1285 1349 4.5E-9 T 22-04-2016 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass TOLA_RS06475 e3c1c60988f7268d809b5c2e4b152259 1368 Gene3D G3DSA:2.150.10.10 1196 1351 8.4E-10 T 22-04-2016 IPR011049 Serralysin-like metalloprotease, C-terminal TOLA_RS06475 e3c1c60988f7268d809b5c2e4b152259 1368 Gene3D G3DSA:2.150.10.10 907 921 8.4E-10 T 22-04-2016 IPR011049 Serralysin-like metalloprotease, C-terminal TOLA_RS06475 e3c1c60988f7268d809b5c2e4b152259 1368 Gene3D G3DSA:2.150.10.10 834 861 8.4E-10 T 22-04-2016 IPR011049 Serralysin-like metalloprotease, C-terminal TOLA_RS06475 e3c1c60988f7268d809b5c2e4b152259 1368 PRINTS PR00313 NodO calcium binding signature 1240 1248 2.7E-6 T 22-04-2016 TOLA_RS06475 e3c1c60988f7268d809b5c2e4b152259 1368 PRINTS PR00313 NodO calcium binding signature 1249 1257 2.7E-6 T 22-04-2016 TOLA_RS06475 e3c1c60988f7268d809b5c2e4b152259 1368 PRINTS PR00313 NodO calcium binding signature 1228 1239 2.7E-6 T 22-04-2016 TOLA_RS06475 e3c1c60988f7268d809b5c2e4b152259 1368 PRINTS PR00313 NodO calcium binding signature 1267 1276 2.7E-6 T 22-04-2016 TOLA_RS06475 e3c1c60988f7268d809b5c2e4b152259 1368 SUPERFAMILY SSF51120 1169 1353 1.22E-26 T 22-04-2016 IPR011049 Serralysin-like metalloprotease, C-terminal TOLA_RS15205 8cacdfb15f88ce0becec756c2f5b85e9 108 SUPERFAMILY SSF81296 26 105 5.13E-12 T 22-04-2016 IPR014756 Immunoglobulin E-set TOLA_RS15205 8cacdfb15f88ce0becec756c2f5b85e9 108 Gene3D G3DSA:2.60.40.10 9 84 2.7E-7 T 22-04-2016 IPR013783 Immunoglobulin-like fold TOLA_RS11550 42be7d6c49e494b299d5812ab8588b6f 296 PIRSF PIRSF015558 6 293 3.8E-92 T 22-04-2016 IPR016634 Transcription regulator, DeoR type, predicted TOLA_RS11550 42be7d6c49e494b299d5812ab8588b6f 296 Pfam PF13280 WYL domain 126 198 8.1E-11 T 22-04-2016 IPR026881 WYL domain TOLA_RS15395 e0d3cf081d06c58bbb62e2372b744dbb 71 Pfam PF04400 Protein of unknown function (DUF539) 22 59 3.7E-20 T 22-04-2016 IPR007495 (Na+)-NQR maturation factor NqrM TOLA_RS15395 e0d3cf081d06c58bbb62e2372b744dbb 71 PANTHER PTHR40691 2 64 7.1E-22 T 22-04-2016 TOLA_RS11045 623bbeebd7320611a4ad320e251c4eb4 212 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 6 204 6.9E-66 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TOLA_RS11045 623bbeebd7320611a4ad320e251c4eb4 212 Pfam PF01914 MarC family integral membrane protein 6 208 4.5E-62 T 22-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TOLA_RS11045 623bbeebd7320611a4ad320e251c4eb4 212 PANTHER PTHR33508:SF1 5 211 1.0E-83 T 22-04-2016 TOLA_RS11045 623bbeebd7320611a4ad320e251c4eb4 212 PANTHER PTHR33508 5 211 1.0E-83 T 22-04-2016 TOLA_RS05080 16c33049ec772baad2779de4700b5371 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 305 319 4.3E-16 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS05080 16c33049ec772baad2779de4700b5371 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 390 401 4.3E-16 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS05080 16c33049ec772baad2779de4700b5371 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 377 4.3E-16 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS05080 16c33049ec772baad2779de4700b5371 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 437 449 4.3E-16 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS05080 16c33049ec772baad2779de4700b5371 475 PRINTS PR00131 Glycosyl hydrolase family 1 signature 412 429 4.3E-16 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS05080 16c33049ec772baad2779de4700b5371 475 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 369 377 - T 22-04-2016 IPR018120 Glycoside hydrolase family 1, active site TOLA_RS05080 16c33049ec772baad2779de4700b5371 475 PANTHER PTHR10353 3 475 5.4E-236 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS05080 16c33049ec772baad2779de4700b5371 475 Pfam PF00232 Glycosyl hydrolase family 1 4 472 3.1E-130 T 22-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TOLA_RS05080 16c33049ec772baad2779de4700b5371 475 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 22-04-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site TOLA_RS05080 16c33049ec772baad2779de4700b5371 475 Gene3D G3DSA:3.20.20.80 3 472 6.1E-146 T 22-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 TOLA_RS05080 16c33049ec772baad2779de4700b5371 475 PANTHER PTHR10353:SF35 3 475 5.4E-236 T 22-04-2016 TOLA_RS05080 16c33049ec772baad2779de4700b5371 475 SUPERFAMILY SSF51445 2 468 9.15E-159 T 22-04-2016 IPR017853 Glycoside hydrolase superfamily TOLA_RS13630 5b21615a3cc1d6b10598b14a4d03b47c 61 SUPERFAMILY SSF46955 8 56 1.83E-5 T 22-04-2016 IPR009061 Putative DNA-binding domain TOLA_RS13630 5b21615a3cc1d6b10598b14a4d03b47c 61 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 7 55 4.0E-7 T 22-04-2016 IPR010260 Prophage CP4-57 regulatory protein (AlpA) TOLA_RS10460 ecd4160257a7c814136e2d8e129d5baf 139 Gene3D G3DSA:1.20.120.330 4 134 2.5E-49 T 22-04-2016 TOLA_RS10460 ecd4160257a7c814136e2d8e129d5baf 139 SUPERFAMILY SSF81593 4 127 4.71E-42 T 22-04-2016 TOLA_RS10460 ecd4160257a7c814136e2d8e129d5baf 139 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 9 133 1.9E-43 T 22-04-2016 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 TOLA_RS10460 ecd4160257a7c814136e2d8e129d5baf 139 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 10 127 9.2E-28 T 22-04-2016 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 TOLA_RS12775 185eb46ab3446fba2716eac118e44df1 268 Pfam PF06691 Protein of unknown function (DUF1189) 7 249 3.2E-55 T 22-04-2016 IPR009574 Protein of unknown function DUF1189 TOLA_RS11495 a658e7b191c28aeff5f855fef34b49c8 144 Gene3D G3DSA:3.30.530.20 1 143 1.4E-44 T 22-04-2016 IPR023393 START-like domain TOLA_RS11495 a658e7b191c28aeff5f855fef34b49c8 144 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 13 135 3.5E-30 T 22-04-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain TOLA_RS11495 a658e7b191c28aeff5f855fef34b49c8 144 PANTHER PTHR12901:SF7 1 143 3.2E-62 T 22-04-2016 TOLA_RS11495 a658e7b191c28aeff5f855fef34b49c8 144 SUPERFAMILY SSF55961 1 143 8.25E-33 T 22-04-2016 TOLA_RS11495 a658e7b191c28aeff5f855fef34b49c8 144 PANTHER PTHR12901 1 143 3.2E-62 T 22-04-2016 TOLA_RS15865 9cacb4422727f56f42d9b4789ea27626 88 Gene3D G3DSA:3.30.70.260 1 78 6.6E-17 T 22-04-2016 TOLA_RS15865 9cacb4422727f56f42d9b4789ea27626 88 SUPERFAMILY SSF55021 3 75 5.0E-13 T 22-04-2016 TOLA_RS15865 9cacb4422727f56f42d9b4789ea27626 88 Pfam PF13710 ACT domain 13 73 2.9E-26 T 22-04-2016 TOLA_RS09160 703238d2f8433f1cccd525eda6bf84f0 66 TIGRFAM TIGR03318 YdfZ_fam: putative selenium-binding protein YdfZ 3 66 1.7E-28 T 22-04-2016 IPR017704 Putative selenium-binding protein YdfZ TOLA_RS09160 703238d2f8433f1cccd525eda6bf84f0 66 Pfam PF14001 YdfZ protein 3 66 1.1E-32 T 22-04-2016 IPR017704 Putative selenium-binding protein YdfZ TOLA_RS05970 4d9f3bc61ce4643d9370632248fd8ae9 555 Gene3D G3DSA:3.40.50.300 48 210 9.4E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS05970 4d9f3bc61ce4643d9370632248fd8ae9 555 Pfam PF01926 50S ribosome-binding GTPase 52 159 3.4E-12 T 22-04-2016 IPR006073 GTP binding domain GO:0005525 TOLA_RS05970 4d9f3bc61ce4643d9370632248fd8ae9 555 SUPERFAMILY SSF52540 46 215 2.21E-19 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS03905 60145329c32d00a94f9050ee0e9c8c3a 118 Gene3D G3DSA:3.30.428.10 3 109 5.6E-34 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 TOLA_RS03905 60145329c32d00a94f9050ee0e9c8c3a 118 PRINTS PR00332 Histidine triad family signature 27 45 3.4E-19 T 22-04-2016 IPR001310 Histidine triad (HIT) protein TOLA_RS03905 60145329c32d00a94f9050ee0e9c8c3a 118 PRINTS PR00332 Histidine triad family signature 95 105 3.4E-19 T 22-04-2016 IPR001310 Histidine triad (HIT) protein TOLA_RS03905 60145329c32d00a94f9050ee0e9c8c3a 118 PRINTS PR00332 Histidine triad family signature 6 22 3.4E-19 T 22-04-2016 IPR001310 Histidine triad (HIT) protein TOLA_RS03905 60145329c32d00a94f9050ee0e9c8c3a 118 SUPERFAMILY SSF54197 2 111 2.55E-33 T 22-04-2016 IPR011146 HIT-like domain GO:0003824 TOLA_RS03905 60145329c32d00a94f9050ee0e9c8c3a 118 PANTHER PTHR23089:SF2 2 111 1.7E-47 T 22-04-2016 TOLA_RS03905 60145329c32d00a94f9050ee0e9c8c3a 118 ProSitePatterns PS00892 HIT domain signature. 88 106 - T 22-04-2016 IPR019808 Histidine triad, conserved site TOLA_RS03905 60145329c32d00a94f9050ee0e9c8c3a 118 PANTHER PTHR23089 2 111 1.7E-47 T 22-04-2016 IPR001310 Histidine triad (HIT) protein TOLA_RS03905 60145329c32d00a94f9050ee0e9c8c3a 118 Pfam PF01230 HIT domain 12 109 1.3E-28 T 22-04-2016 IPR001310 Histidine triad (HIT) protein TOLA_RS06335 655c9bab7c8507389a8a42048bff0357 564 Pfam PF10131 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein 77 393 6.9E-15 T 22-04-2016 IPR018776 Membrane protein, 6-pyruvoyl-tetrahydropterin synthase-related domain TOLA_RS03995 722db7367188023577ead79af1000c37 438 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 1 438 2.8E-189 T 22-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 TOLA_RS03995 722db7367188023577ead79af1000c37 438 PANTHER PTHR30354:SF4 1 438 4.3E-275 T 22-04-2016 TOLA_RS03995 722db7367188023577ead79af1000c37 438 PANTHER PTHR30354 1 438 4.3E-275 T 22-04-2016 TOLA_RS03995 722db7367188023577ead79af1000c37 438 PIRSF PIRSF002746 1 438 1.9E-156 T 22-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 TOLA_RS03995 722db7367188023577ead79af1000c37 438 Pfam PF02447 GntP family permease 1 435 1.4E-175 T 22-04-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 TOLA_RS08615 cae22f2c18d49015ccaf2d6c4ccabf9b 166 Pfam PF15953 Putative propanediol utilisation 10 161 3.2E-54 T 22-04-2016 IPR030992 Microcompartment protein PduM GO:0005198 TOLA_RS08615 cae22f2c18d49015ccaf2d6c4ccabf9b 166 TIGRFAM TIGR04493 microcomp_PduM: microcompartment protein PduM 10 162 2.1E-54 T 22-04-2016 IPR030992 Microcompartment protein PduM GO:0005198 TOLA_RS01830 895b865a4aee153d4995721406de0359 323 Pfam PF01545 Cation efflux family 23 252 3.0E-41 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TOLA_RS01830 895b865a4aee153d4995721406de0359 323 Gene3D G3DSA:1.20.1510.10 185 252 6.3E-51 T 22-04-2016 IPR027469 Cation efflux protein transmembrane domain TOLA_RS01830 895b865a4aee153d4995721406de0359 323 Gene3D G3DSA:1.20.1510.10 17 146 6.3E-51 T 22-04-2016 IPR027469 Cation efflux protein transmembrane domain TOLA_RS01830 895b865a4aee153d4995721406de0359 323 PANTHER PTHR11562:SF40 170 321 4.5E-119 T 22-04-2016 TOLA_RS01830 895b865a4aee153d4995721406de0359 323 PANTHER PTHR11562:SF40 16 143 4.5E-119 T 22-04-2016 TOLA_RS01830 895b865a4aee153d4995721406de0359 323 PANTHER PTHR11562 170 321 4.5E-119 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TOLA_RS01830 895b865a4aee153d4995721406de0359 323 PANTHER PTHR11562 16 143 4.5E-119 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TOLA_RS01830 895b865a4aee153d4995721406de0359 323 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 17 303 3.2E-58 T 22-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TOLA_RS01830 895b865a4aee153d4995721406de0359 323 SUPERFAMILY SSF161111 185 253 1.57E-50 T 22-04-2016 TOLA_RS01830 895b865a4aee153d4995721406de0359 323 SUPERFAMILY SSF161111 16 146 1.57E-50 T 22-04-2016 TOLA_RS15225 ddcb3f152e9e8c8265450044333edf6e 82 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 79 1.2E-29 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15225 ddcb3f152e9e8c8265450044333edf6e 82 PANTHER PTHR12919 1 78 1.9E-40 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15225 ddcb3f152e9e8c8265450044333edf6e 82 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 24.206 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15225 ddcb3f152e9e8c8265450044333edf6e 82 Pfam PF00886 Ribosomal protein S16 8 68 3.9E-24 T 22-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TOLA_RS15225 ddcb3f152e9e8c8265450044333edf6e 82 Gene3D G3DSA:3.30.1320.10 1 78 3.8E-33 T 22-04-2016 IPR023803 Ribosomal protein S16 domain TOLA_RS15225 ddcb3f152e9e8c8265450044333edf6e 82 SUPERFAMILY SSF54565 1 78 6.15E-29 T 22-04-2016 IPR023803 Ribosomal protein S16 domain TOLA_RS01675 02800ed22fc53615f051d64845167693 112 Pfam PF00581 Rhodanese-like domain 23 91 1.8E-7 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS01675 02800ed22fc53615f051d64845167693 112 SUPERFAMILY SSF52821 21 91 4.98E-17 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS01675 02800ed22fc53615f051d64845167693 112 SMART SM00450 7 103 1.1E-5 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS01675 02800ed22fc53615f051d64845167693 112 Gene3D G3DSA:3.40.250.10 22 96 3.6E-18 T 22-04-2016 IPR001763 Rhodanese-like domain TOLA_RS11425 ec11d1e4bdd485f29f45f3c75bb6b6e5 115 PANTHER PTHR34182 2 84 3.6E-29 T 22-04-2016 TOLA_RS11425 ec11d1e4bdd485f29f45f3c75bb6b6e5 115 Pfam PF03840 Preprotein translocase SecG subunit 4 72 1.4E-22 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TOLA_RS11425 ec11d1e4bdd485f29f45f3c75bb6b6e5 115 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 1.2E-26 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TOLA_RS11425 ec11d1e4bdd485f29f45f3c75bb6b6e5 115 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.4E-41 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TOLA_RS11425 ec11d1e4bdd485f29f45f3c75bb6b6e5 115 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 1.4E-41 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TOLA_RS11425 ec11d1e4bdd485f29f45f3c75bb6b6e5 115 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.4E-41 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TOLA_RS11425 ec11d1e4bdd485f29f45f3c75bb6b6e5 115 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 1.4E-41 T 22-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TOLA_RS12350 db8fe388aac177439bd98780c1d254b1 595 Gene3D G3DSA:3.40.50.300 1 354 8.5E-21 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12350 db8fe388aac177439bd98780c1d254b1 595 SUPERFAMILY SSF52540 187 352 6.36E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12350 db8fe388aac177439bd98780c1d254b1 595 SUPERFAMILY SSF52540 1 113 6.36E-16 T 22-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TOLA_RS12350 db8fe388aac177439bd98780c1d254b1 595 Pfam PF13175 AAA ATPase domain 183 341 4.1E-17 T 22-04-2016 TOLA_RS14590 3d23ca2f8b56af06ce189d1aeaab92c4 85 Gene3D G3DSA:3.40.1620.10 22 49 4.6E-7 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TOLA_RS14590 3d23ca2f8b56af06ce189d1aeaab92c4 85 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 56 1.7E-9 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TOLA_RS14590 3d23ca2f8b56af06ce189d1aeaab92c4 85 PANTHER PTHR33713:SF3 1 85 4.0E-56 T 22-04-2016 TOLA_RS14590 3d23ca2f8b56af06ce189d1aeaab92c4 85 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 71 6.4E-14 T 22-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TOLA_RS14590 3d23ca2f8b56af06ce189d1aeaab92c4 85 PANTHER PTHR33713 1 85 4.0E-56 T 22-04-2016 TOLA_RS14590 3d23ca2f8b56af06ce189d1aeaab92c4 85 SUPERFAMILY SSF143120 1 75 3.49E-16 T 22-04-2016 TOLA_RS05780 b2525608570c7da2fd43be8d5941c85a 155 SUPERFAMILY SSF52833 4 155 1.88E-46 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS05780 b2525608570c7da2fd43be8d5941c85a 155 Gene3D G3DSA:3.40.30.10 2 155 3.4E-46 T 22-04-2016 IPR012336 Thioredoxin-like fold TOLA_RS05780 b2525608570c7da2fd43be8d5941c85a 155 Pfam PF00578 AhpC/TSA family 7 134 3.9E-35 T 22-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 TOLA_RS05780 b2525608570c7da2fd43be8d5941c85a 155 PANTHER PTHR10681 1 155 4.4E-46 T 22-04-2016 TOLA_RS05780 b2525608570c7da2fd43be8d5941c85a 155 PIRSF PIRSF000239 1 155 7.0E-18 T 22-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 95 108 4.12E-57 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 74 90 4.12E-57 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 138 155 4.12E-57 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 5 20 4.12E-57 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 164 175 4.12E-57 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 109 129 4.12E-57 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 4.12E-57 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 Pfam PF02056 Family 4 glycosyl hydrolase 6 184 1.1E-63 T 22-04-2016 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 Gene3D G3DSA:3.40.50.720 1 165 5.8E-64 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 SUPERFAMILY SSF56327 168 441 2.73E-89 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 PANTHER PTHR32092:SF7 1 442 1.8E-301 T 22-04-2016 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 417 1.4E-51 T 22-04-2016 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 138 169 - T 22-04-2016 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 PANTHER PTHR32092 1 442 1.8E-301 T 22-04-2016 TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 SUPERFAMILY SSF51735 3 164 3.94E-51 T 22-04-2016 IPR016040 NAD(P)-binding domain TOLA_RS13510 3a5e12f83a5aa48edb791f5f28923be0 442 Gene3D G3DSA:3.90.110.10 167 441 3.4E-101 T 22-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TOLA_RS03535 841fb7f795e8c03d29c2ebdbc2e0b413 160 Pfam PF07308 Protein of unknown function (DUF1456) 3 70 4.1E-27 T 22-04-2016 IPR009921 Domain of unknown function DUF1456 TOLA_RS03535 841fb7f795e8c03d29c2ebdbc2e0b413 160 Pfam PF07308 Protein of unknown function (DUF1456) 85 151 1.1E-26 T 22-04-2016 IPR009921 Domain of unknown function DUF1456 TOLA_RS03535 841fb7f795e8c03d29c2ebdbc2e0b413 160 PANTHER PTHR37805:SF1 1 155 8.8E-64 T 22-04-2016 TOLA_RS03535 841fb7f795e8c03d29c2ebdbc2e0b413 160 PANTHER PTHR37805 1 155 8.8E-64 T 22-04-2016 TOLA_RS03330 8eee38b0100df3f2190813bc786920d4 357 Pfam PF13533 Biotin-lipoyl like 69 117 1.6E-12 T 22-04-2016 TOLA_RS03330 8eee38b0100df3f2190813bc786920d4 357 PANTHER PTHR32347 17 342 6.8E-12 T 22-04-2016 TOLA_RS03330 8eee38b0100df3f2190813bc786920d4 357 Gene3D G3DSA:2.40.50.100 218 253 2.4E-11 T 22-04-2016 TOLA_RS03330 8eee38b0100df3f2190813bc786920d4 357 Gene3D G3DSA:2.40.50.100 69 101 2.4E-11 T 22-04-2016 TOLA_RS03330 8eee38b0100df3f2190813bc786920d4 357 SUPERFAMILY SSF51230 214 255 9.87E-5 T 22-04-2016 IPR011053 Single hybrid motif TOLA_RS03330 8eee38b0100df3f2190813bc786920d4 357 Pfam PF13437 HlyD family secretion protein 226 297 4.6E-6 T 22-04-2016 TOLA_RS13875 f13dd2a93403a907b805711ad8e05c02 155 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 114 124 - T 22-04-2016 IPR020549 Endoribonuclease YbeY, conserved site TOLA_RS13875 f13dd2a93403a907b805711ad8e05c02 155 Pfam PF02130 Uncharacterized protein family UPF0054 20 143 7.5E-39 T 22-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TOLA_RS13875 f13dd2a93403a907b805711ad8e05c02 155 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 4 148 24.508 T 22-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TOLA_RS13875 f13dd2a93403a907b805711ad8e05c02 155 SUPERFAMILY SSF55486 3 150 3.85E-48 T 22-04-2016 TOLA_RS13875 f13dd2a93403a907b805711ad8e05c02 155 PANTHER PTHR22881 1 150 1.6E-62 T 22-04-2016 TOLA_RS13875 f13dd2a93403a907b805711ad8e05c02 155 Gene3D G3DSA:3.40.390.30 12 152 2.5E-50 T 22-04-2016 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 TOLA_RS13875 f13dd2a93403a907b805711ad8e05c02 155 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 144 5.2E-37 T 22-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TOLA_RS11780 cd5d815988ad3873aa8c2a945a6f9360 234 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 33 219 4.4E-66 T 22-04-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 TOLA_RS11780 cd5d815988ad3873aa8c2a945a6f9360 234 SUPERFAMILY SSF55729 5 232 1.8E-91 T 22-04-2016 IPR016181 Acyl-CoA N-acyltransferase TOLA_RS11780 cd5d815988ad3873aa8c2a945a6f9360 234 PANTHER PTHR30098:SF2 1 232 7.3E-78 T 22-04-2016 TOLA_RS11780 cd5d815988ad3873aa8c2a945a6f9360 234 PANTHER PTHR30098 1 232 7.3E-78 T 22-04-2016 TOLA_RS11780 cd5d815988ad3873aa8c2a945a6f9360 234 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 234 97.096 T 22-04-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 TOLA_RS11780 cd5d815988ad3873aa8c2a945a6f9360 234 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 36 205 2.3E-72 T 22-04-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 TOLA_RS11485 44c25102ebe233fc035019b34c57dc34 113 PANTHER PTHR37482 2 113 1.1E-31 T 22-04-2016 TOLA_RS11485 44c25102ebe233fc035019b34c57dc34 113 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 6 112 26.864 T 22-04-2016 IPR026592 Outer membrane protein assembly factor BamE TOLA_RS11485 44c25102ebe233fc035019b34c57dc34 113 Pfam PF04355 SmpA / OmlA family 31 98 1.6E-23 T 22-04-2016 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 TOLA_RS11485 44c25102ebe233fc035019b34c57dc34 113 PANTHER PTHR37482:SF1 2 113 1.1E-31 T 22-04-2016 TOLA_RS04760 63e4d58cde860eb79fbee700df9eaa27 108 PANTHER PTHR34981 4 99 6.3E-20 T 22-04-2016 TOLA_RS04760 63e4d58cde860eb79fbee700df9eaa27 108 PANTHER PTHR34981:SF1 4 99 6.3E-20 T 22-04-2016 TOLA_RS04760 63e4d58cde860eb79fbee700df9eaa27 108 Pfam PF05164 Cell division protein ZapA 8 90 2.0E-18 T 22-04-2016 IPR007838 Cell division protein ZapA-like TOLA_RS04760 63e4d58cde860eb79fbee700df9eaa27 108 SUPERFAMILY SSF102829 8 97 1.02E-21 T 22-04-2016 IPR007838 Cell division protein ZapA-like TOLA_RS07780 991c7b1d88e61c055be890fe5067cb15 193 Gene3D G3DSA:2.70.40.10 1 192 6.0E-61 T 22-04-2016 IPR029054 dUTPase-like TOLA_RS07780 991c7b1d88e61c055be890fe5067cb15 193 Pfam PF00692 dUTPase 78 184 8.6E-8 T 22-04-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 TOLA_RS07780 991c7b1d88e61c055be890fe5067cb15 193 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 190 1.4E-67 T 22-04-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187|UniPathway: UPA00610 TOLA_RS07780 991c7b1d88e61c055be890fe5067cb15 193 PANTHER PTHR11241 77 192 1.1E-64 T 22-04-2016 TOLA_RS07780 991c7b1d88e61c055be890fe5067cb15 193 PANTHER PTHR11241 1 58 1.1E-64 T 22-04-2016 TOLA_RS07780 991c7b1d88e61c055be890fe5067cb15 193 PANTHER PTHR11241:SF1 77 192 1.1E-64 T 22-04-2016 TOLA_RS07780 991c7b1d88e61c055be890fe5067cb15 193 PANTHER PTHR11241:SF1 1 58 1.1E-64 T 22-04-2016 TOLA_RS07780 991c7b1d88e61c055be890fe5067cb15 193 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 190 33.518 T 22-04-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187|UniPathway: UPA00610 TOLA_RS07780 991c7b1d88e61c055be890fe5067cb15 193 SUPERFAMILY SSF51283 1 193 6.67E-60 T 22-04-2016 IPR029054 dUTPase-like TOLA_RS01135 3c783b8c0d3c2ddf33a9e8de3fac5e4c 445 Pfam PF03390 2-hydroxycarboxylate transporter family 31 439 2.1E-151 T 22-04-2016 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 TOLA_RS01135 3c783b8c0d3c2ddf33a9e8de3fac5e4c 445 PIRSF PIRSF005348 13 445 4.4E-157 T 22-04-2016 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 TOLA_RS01135 3c783b8c0d3c2ddf33a9e8de3fac5e4c 445 PANTHER PTHR40033 1 445 9.1E-152 T 22-04-2016 TOLA_RS13540 de4df46b415e3c8220264faec17ba23f 500 Pfam PF01928 CYTH domain 3 197 2.2E-24 T 22-04-2016 IPR023577 CYTH domain TOLA_RS13540 de4df46b415e3c8220264faec17ba23f 500 PANTHER PTHR39569 2 500 6.0E-82 T 22-04-2016 TOLA_RS13540 de4df46b415e3c8220264faec17ba23f 500 PANTHER PTHR39569:SF1 2 500 6.0E-82 T 22-04-2016 TOLA_RS13540 de4df46b415e3c8220264faec17ba23f 500 SUPERFAMILY SSF55154 1 216 1.11E-47 T 22-04-2016 IPR033469 CYTH-like domain TOLA_RS13540 de4df46b415e3c8220264faec17ba23f 500 SMART SM01118 2 203 2.0E-34 T 22-04-2016 IPR023577 CYTH domain TOLA_RS13540 de4df46b415e3c8220264faec17ba23f 500 Gene3D G3DSA:2.40.320.10 2 201 1.1E-32 T 22-04-2016 IPR023577 CYTH domain TOLA_RS14465 d1008e4fe5821813a31708f2441be452 166 Pfam PF07295 Zinc-ribbon containing domain 26 162 3.3E-40 T 22-04-2016 IPR009912 Zinc-ribbon containing domain TOLA_RS08690 d2d5d3fbe7125135f4a499db2c626c81 437 SUPERFAMILY SSF53850 51 431 8.8E-62 T 22-04-2016 TOLA_RS08690 d2d5d3fbe7125135f4a499db2c626c81 437 Gene3D G3DSA:3.40.190.10 158 363 8.2E-30 T 22-04-2016 TOLA_RS08690 d2d5d3fbe7125135f4a499db2c626c81 437 PANTHER PTHR30061 55 437 3.0E-48 T 22-04-2016 TOLA_RS08690 d2d5d3fbe7125135f4a499db2c626c81 437 Pfam PF01547 Bacterial extracellular solute-binding protein 59 354 5.2E-28 T 22-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 TOLA_RS08690 d2d5d3fbe7125135f4a499db2c626c81 437 Gene3D G3DSA:3.40.190.10 46 157 3.5E-4 T 22-04-2016 TOLA_RS11035 b9c494f5e7fecc379d430dd4ea2885f8 448 PANTHER PTHR30008 1 448 5.5E-173 T 22-04-2016 TOLA_RS11035 b9c494f5e7fecc379d430dd4ea2885f8 448 PANTHER PTHR30008:SF0 1 448 5.5E-173 T 22-04-2016 TOLA_RS11035 b9c494f5e7fecc379d430dd4ea2885f8 448 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 6 442 29.856 T 22-04-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 TOLA_RS11035 b9c494f5e7fecc379d430dd4ea2885f8 448 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 10 356 2.1E-134 T 22-04-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 TOLA_RS11035 b9c494f5e7fecc379d430dd4ea2885f8 448 Pfam PF13742 OB-fold nucleic acid binding domain 9 102 1.4E-30 T 22-04-2016 IPR025824 OB-fold nucleic acid binding domain GO:0003676 TOLA_RS11035 b9c494f5e7fecc379d430dd4ea2885f8 448 Pfam PF02601 Exonuclease VII, large subunit 125 439 1.3E-98 T 22-04-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 TOLA_RS08110 25733ccff90a53dc28273ca2b8a23445 913 SUPERFAMILY SSF88659 403 448 1.28E-7 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS08110 25733ccff90a53dc28273ca2b8a23445 913 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 421 447 - T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS08110 25733ccff90a53dc28273ca2b8a23445 913 Pfam PF04545 Sigma-70, region 4 404 447 1.1E-8 T 22-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS08110 25733ccff90a53dc28273ca2b8a23445 913 PRINTS PR00046 Major sigma-70 factor signature 421 436 6.9E-7 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS08110 25733ccff90a53dc28273ca2b8a23445 913 PRINTS PR00046 Major sigma-70 factor signature 436 447 6.9E-7 T 22-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS08110 25733ccff90a53dc28273ca2b8a23445 913 Gene3D G3DSA:1.10.10.10 404 447 4.9E-11 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05595 39bb9068ccf5b637d697aada8d3872d2 248 SMART SM00304 192 245 1.1E-4 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS05595 39bb9068ccf5b637d697aada8d3872d2 248 Pfam PF00672 HAMP domain 175 240 9.7E-9 T 22-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TOLA_RS00280 c42d79dc5018ff3f214db53232b1e551 229 Pfam PF07385 Protein of unknown function (DUF1498) 1 223 2.5E-99 T 22-04-2016 IPR010864 Protein of unknown function DUF1498 KEGG: 00040+5.3.1.15 TOLA_RS00280 c42d79dc5018ff3f214db53232b1e551 229 SUPERFAMILY SSF51182 91 183 2.56E-7 T 22-04-2016 IPR011051 RmlC-like cupin domain TOLA_RS01325 4a81acd5ac236f4bc0e917cb1e286df1 217 PANTHER PTHR30450:SF1 1 217 1.1E-117 T 22-04-2016 TOLA_RS01325 4a81acd5ac236f4bc0e917cb1e286df1 217 Gene3D G3DSA:1.10.3720.10 8 216 4.9E-46 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS01325 4a81acd5ac236f4bc0e917cb1e286df1 217 PANTHER PTHR30450 1 217 1.1E-117 T 22-04-2016 TOLA_RS01325 4a81acd5ac236f4bc0e917cb1e286df1 217 SUPERFAMILY SSF161098 8 201 2.22E-47 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS01325 4a81acd5ac236f4bc0e917cb1e286df1 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 215 1.8E-22 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS00460 dbdb7ee67ccd447eb6e01280149a439f 224 PANTHER PTHR31088 2 217 7.9E-79 T 22-04-2016 TOLA_RS00460 dbdb7ee67ccd447eb6e01280149a439f 224 Pfam PF04012 PspA/IM30 family 2 216 1.4E-40 T 22-04-2016 IPR007157 PspA/IM30 TOLA_RS00460 dbdb7ee67ccd447eb6e01280149a439f 224 TIGRFAM TIGR02977 phageshock_pspA: phage shock protein A 1 218 6.1E-87 T 22-04-2016 IPR014319 Phage shock protein, PspA TOLA_RS00460 dbdb7ee67ccd447eb6e01280149a439f 224 PANTHER PTHR31088:SF7 2 217 7.9E-79 T 22-04-2016 TOLA_RS05040 038371ab91b8035f288844a32796ce92 195 SUPERFAMILY SSF50475 9 187 1.57E-22 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 TOLA_RS05040 038371ab91b8035f288844a32796ce92 195 Pfam PF01613 Flavin reductase like domain 15 183 1.0E-7 T 22-04-2016 IPR002563 Flavin reductase like domain GO:0010181 TOLA_RS05040 038371ab91b8035f288844a32796ce92 195 Gene3D G3DSA:2.30.110.10 12 187 4.6E-27 T 22-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 TOLA_RS06755 a579d616d59dd1f82bbd2f3df0dc18af 371 Gene3D G3DSA:3.40.50.1820 35 370 3.1E-99 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS06755 a579d616d59dd1f82bbd2f3df0dc18af 371 SUPERFAMILY SSF53474 68 367 1.17E-25 T 22-04-2016 IPR029058 Alpha/Beta hydrolase fold TOLA_RS06755 a579d616d59dd1f82bbd2f3df0dc18af 371 PANTHER PTHR11177 133 364 2.7E-62 T 22-04-2016 TOLA_RS06755 a579d616d59dd1f82bbd2f3df0dc18af 371 PANTHER PTHR11177:SF162 133 364 2.7E-62 T 22-04-2016 TOLA_RS05755 5889252881420858947acf2f8df88594 166 Pfam PF03887 YfbU domain 1 166 1.4E-65 T 22-04-2016 IPR005587 Uncharacterised protein family UPF0304, YfbU TOLA_RS05755 5889252881420858947acf2f8df88594 166 ProDom PD035118 UPF0304 YFBU PLASMID YPO2563/Y1624/YP2374 YBFU PM1500 OXYGEN ECA3037 VV12093 PROTEIN 1 166 2.0E-43 T 22-04-2016 IPR005587 Uncharacterised protein family UPF0304, YfbU TOLA_RS05755 5889252881420858947acf2f8df88594 166 Gene3D G3DSA:1.10.287.680 1 52 9.8E-27 T 22-04-2016 IPR023145 YfbU, helix-hairpin domain TOLA_RS05755 5889252881420858947acf2f8df88594 166 Gene3D G3DSA:1.10.3190.10 53 165 1.9E-37 T 22-04-2016 IPR023146 YfbU, alpha-helical bundle domain TOLA_RS05755 5889252881420858947acf2f8df88594 166 SUPERFAMILY SSF116960 1 166 1.18E-56 T 22-04-2016 TOLA_RS12600 65f172ae2dc68343eec9808f0815161c 357 Gene3D G3DSA:2.40.128.140 24 353 5.7E-104 T 22-04-2016 TOLA_RS12600 65f172ae2dc68343eec9808f0815161c 357 Pfam PF09982 Uncharacterized protein conserved in bacteria (DUF2219) 50 354 1.3E-91 T 22-04-2016 IPR018707 Protein of unknown function DUF2219 TOLA_RS13320 65c1b9607bab52cddbf99e02ebf404f8 77 Gene3D G3DSA:2.30.30.100 19 77 6.2E-23 T 22-04-2016 TOLA_RS13320 65c1b9607bab52cddbf99e02ebf404f8 77 SUPERFAMILY SSF50182 19 77 3.27E-17 T 22-04-2016 IPR010920 LSM domain TOLA_RS13320 65c1b9607bab52cddbf99e02ebf404f8 77 PANTHER PTHR34772:SF1 14 77 9.9E-18 T 22-04-2016 TOLA_RS13320 65c1b9607bab52cddbf99e02ebf404f8 77 PANTHER PTHR34772 14 77 9.9E-18 T 22-04-2016 TOLA_RS13320 65c1b9607bab52cddbf99e02ebf404f8 77 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 20 77 3.3E-21 T 22-04-2016 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 TOLA_RS13320 65c1b9607bab52cddbf99e02ebf404f8 77 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 13 77 25.578 T 22-04-2016 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 TOLA_RS04530 9a316b7389932b3110b93b9c63b1b965 584 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 58 390 5.5E-77 T 22-04-2016 IPR003776 YcaO-like domain TOLA_RS04530 9a316b7389932b3110b93b9c63b1b965 584 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 10 403 7.9E-150 T 22-04-2016 IPR003776 YcaO-like domain TOLA_RS08360 44e6823df60d765cbcf50f72e13272a9 135 PANTHER PTHR33452 6 128 2.2E-22 T 22-04-2016 TOLA_RS08360 44e6823df60d765cbcf50f72e13272a9 135 Pfam PF07681 DoxX 11 92 1.7E-16 T 22-04-2016 IPR032808 DoxX family TOLA_RS08360 44e6823df60d765cbcf50f72e13272a9 135 PANTHER PTHR33452:SF1 6 128 2.2E-22 T 22-04-2016 TOLA_RS09310 123fffcec7496eb633fbe1b893dd0e1c 360 PANTHER PTHR32196 18 360 2.8E-128 T 22-04-2016 TOLA_RS09310 123fffcec7496eb633fbe1b893dd0e1c 360 PANTHER PTHR32196:SF21 18 360 2.8E-128 T 22-04-2016 TOLA_RS09310 123fffcec7496eb633fbe1b893dd0e1c 360 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 337 1.4E-48 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS12805 c262c3164232a6e990fca3bda3981f42 398 Pfam PF14341 PilX N-terminal 8 58 4.4E-10 T 22-04-2016 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain TOLA_RS11005 65489770d69ab0bcf04f23e64bc57e1c 91 PANTHER PTHR35175 8 84 1.0E-34 T 22-04-2016 TOLA_RS11005 65489770d69ab0bcf04f23e64bc57e1c 91 Pfam PF06945 Protein of unknown function (DUF1289) 17 63 3.4E-19 T 22-04-2016 IPR010710 Protein of unknown function DUF1289 TOLA_RS11005 65489770d69ab0bcf04f23e64bc57e1c 91 PANTHER PTHR35175:SF1 8 84 1.0E-34 T 22-04-2016 TOLA_RS12515 e56c318528a85a43f6cacd4a78ebefc4 481 PANTHER PTHR10283:SF90 17 477 7.5E-157 T 22-04-2016 TOLA_RS12515 e56c318528a85a43f6cacd4a78ebefc4 481 Pfam PF03606 C4-dicarboxylate anaerobic carrier 19 477 1.1E-132 T 22-04-2016 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 TOLA_RS12515 e56c318528a85a43f6cacd4a78ebefc4 481 PANTHER PTHR10283 17 477 7.5E-157 T 22-04-2016 TOLA_RS08080 e96591e13a8ad82b102172147df7a1c8 367 Pfam PF13395 HNH endonuclease 241 289 1.1E-12 T 22-04-2016 IPR003615 HNH nuclease TOLA_RS12475 31ed42bac4bbd261b424cd0c1f50ec0f 121 Pfam PF12553 Protein of unknown function (DUF3742) 1 119 2.6E-43 T 22-04-2016 IPR022213 Protein of unknown function DUF3742 TOLA_RS08125 6d06f79d01b764f8f374fdc0219a1c3e 242 TIGRFAM TIGR03238 dnd_assoc_3: DNA phosphorothioation-dependent restriction protein DptF 29 197 7.5E-41 T 22-04-2016 IPR017647 DNA phosphorothioation-dependent restriction protein DptF TOLA_RS07185 00d6501f0449ff8f287ca7d1702fcfe5 249 Gene3D G3DSA:2.60.120.200 24 249 2.7E-59 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain TOLA_RS07185 00d6501f0449ff8f287ca7d1702fcfe5 249 SUPERFAMILY SSF49899 29 247 1.58E-46 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain TOLA_RS07185 00d6501f0449ff8f287ca7d1702fcfe5 249 Pfam PF08787 Alginate lyase 29 246 4.0E-49 T 22-04-2016 IPR014895 Alginate lyase 2 TOLA_RS10290 52412e267e682119c4cc88b8834ca388 289 PANTHER PTHR30217 1 288 1.6E-144 T 22-04-2016 TOLA_RS10290 52412e267e682119c4cc88b8834ca388 289 PANTHER PTHR30217:SF8 1 288 1.6E-144 T 22-04-2016 TOLA_RS10290 52412e267e682119c4cc88b8834ca388 289 Pfam PF01136 Peptidase family U32 81 237 4.7E-14 T 22-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- TOLA_RS05685 1cd4c5df74fecc4f0863920d429a90ac 347 PANTHER PTHR30222:SF2 1 347 5.9E-153 T 22-04-2016 TOLA_RS05685 1cd4c5df74fecc4f0863920d429a90ac 347 PANTHER PTHR30222 1 347 5.9E-153 T 22-04-2016 TOLA_RS05685 1cd4c5df74fecc4f0863920d429a90ac 347 SUPERFAMILY SSF53850 25 344 4.6E-65 T 22-04-2016 TOLA_RS05685 1cd4c5df74fecc4f0863920d429a90ac 347 Pfam PF13416 Bacterial extracellular solute-binding protein 44 302 1.8E-43 T 22-04-2016 TOLA_RS05685 1cd4c5df74fecc4f0863920d429a90ac 347 Gene3D G3DSA:3.40.190.10 143 286 3.0E-31 T 22-04-2016 TOLA_RS05685 1cd4c5df74fecc4f0863920d429a90ac 347 Gene3D G3DSA:3.40.190.10 34 142 1.1E-10 T 22-04-2016 TOLA_RS06410 310d6ceb731103466d7b09ad1cdac2a5 168 PANTHER PTHR38773 6 164 8.6E-59 T 22-04-2016 TOLA_RS06410 310d6ceb731103466d7b09ad1cdac2a5 168 SMART SM00731 8 158 2.5E-33 T 22-04-2016 IPR006640 SprT-like TOLA_RS06410 310d6ceb731103466d7b09ad1cdac2a5 168 Pfam PF10263 SprT-like family 20 156 4.5E-26 T 22-04-2016 IPR006640 SprT-like TOLA_RS06410 310d6ceb731103466d7b09ad1cdac2a5 168 Gene3D G3DSA:2.30.170.10 121 154 1.3E-4 T 22-04-2016 TOLA_RS15890 c72a2248a79943f1a728b691f3838f4b 211 Gene3D G3DSA:1.10.357.10 7 180 1.7E-18 T 22-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 TOLA_RS15890 c72a2248a79943f1a728b691f3838f4b 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 54 2.3E-8 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS15890 c72a2248a79943f1a728b691f3838f4b 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.2E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS15890 c72a2248a79943f1a728b691f3838f4b 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.2E-5 T 22-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TOLA_RS15890 c72a2248a79943f1a728b691f3838f4b 211 SUPERFAMILY SSF46689 8 61 2.67E-11 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS10155 e6ceb999399fc43931f4906cccc79580 138 Gene3D G3DSA:3.40.1260.10 34 120 1.2E-13 T 22-04-2016 IPR027396 DsrEFH-like TOLA_RS10155 e6ceb999399fc43931f4906cccc79580 138 Pfam PF02635 DsrE/DsrF-like family 36 119 8.2E-10 T 22-04-2016 IPR003787 Sulphur relay, DsrE/F-like protein TOLA_RS10155 e6ceb999399fc43931f4906cccc79580 138 SUPERFAMILY SSF75169 29 124 1.08E-13 T 22-04-2016 IPR027396 DsrEFH-like TOLA_RS12450 9ed54b7a4c89fa68c856d9d56a61427d 141 Pfam PF07511 Protein of unknown function (DUF1525) 27 138 2.0E-37 T 22-04-2016 IPR011090 Integrating conjugative element protein, PFL4709 TOLA_RS12450 9ed54b7a4c89fa68c856d9d56a61427d 141 TIGRFAM TIGR03757 conj_TIGR03757: integrating conjugative element protein, PFL_4709 family 27 137 1.5E-38 T 22-04-2016 IPR011090 Integrating conjugative element protein, PFL4709 TOLA_RS13240 21aa2d431face9ccdada77de3c7337f3 200 PANTHER PTHR33545 5 195 4.9E-54 T 22-04-2016 TOLA_RS13240 21aa2d431face9ccdada77de3c7337f3 200 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 12 187 8.0E-34 T 22-04-2016 IPR003740 Uncharacterised membrane protein YitT TOLA_RS00390 8658ed50cc0e6463d314162df84af4db 287 Pfam PF13503 Domain of unknown function (DUF4123) 17 137 2.5E-24 T 22-04-2016 IPR025391 Domain of unknown function DUF4123 TOLA_RS10445 3fda9bff0cc9a0299d774fe72b53a319 372 PANTHER PTHR32309:SF16 3 344 1.2E-15 T 22-04-2016 TOLA_RS10445 3fda9bff0cc9a0299d774fe72b53a319 372 PANTHER PTHR32309 3 344 1.2E-15 T 22-04-2016 TOLA_RS10445 3fda9bff0cc9a0299d774fe72b53a319 372 SUPERFAMILY SSF160355 63 335 8.5E-59 T 22-04-2016 TOLA_RS10445 3fda9bff0cc9a0299d774fe72b53a319 372 Gene3D G3DSA:3.30.1890.10 274 335 9.6E-58 T 22-04-2016 TOLA_RS10445 3fda9bff0cc9a0299d774fe72b53a319 372 Gene3D G3DSA:3.30.1890.10 64 235 9.6E-58 T 22-04-2016 TOLA_RS10445 3fda9bff0cc9a0299d774fe72b53a319 372 Pfam PF02706 Chain length determinant protein 24 186 6.5E-13 T 22-04-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 TOLA_RS03225 e1dba28d297429206e386e258d2bc10d 171 SUPERFAMILY SSF51261 21 169 3.31E-55 T 22-04-2016 IPR011055 Duplicated hybrid motif TOLA_RS03225 e1dba28d297429206e386e258d2bc10d 171 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 87 99 - T 22-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS03225 e1dba28d297429206e386e258d2bc10d 171 Gene3D G3DSA:2.70.70.10 19 169 1.3E-59 T 22-04-2016 TOLA_RS03225 e1dba28d297429206e386e258d2bc10d 171 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 24 148 1.6E-49 T 22-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS03225 e1dba28d297429206e386e258d2bc10d 171 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 25 145 3.1E-50 T 22-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- TOLA_RS03225 e1dba28d297429206e386e258d2bc10d 171 PANTHER PTHR30175 1 120 4.5E-51 T 22-04-2016 TOLA_RS08450 1365674889dc6efa16f09232fd72f2d0 93 SUPERFAMILY SSF88659 33 81 3.27E-5 T 22-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TOLA_RS08450 1365674889dc6efa16f09232fd72f2d0 93 Gene3D G3DSA:1.10.10.10 33 82 4.5E-5 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS08450 1365674889dc6efa16f09232fd72f2d0 93 Pfam PF02001 Protein of unknown function DUF134 2 90 2.9E-23 T 22-04-2016 IPR002852 Uncharacterised protein family UPF0251 TOLA_RS08450 1365674889dc6efa16f09232fd72f2d0 93 PANTHER PTHR37478:SF1 1 89 2.2E-26 T 22-04-2016 TOLA_RS08450 1365674889dc6efa16f09232fd72f2d0 93 PANTHER PTHR37478 1 89 2.2E-26 T 22-04-2016 TOLA_RS08450 1365674889dc6efa16f09232fd72f2d0 93 Hamap MF_00674 UPF0251 protein . 2 93 22.581 T 22-04-2016 IPR002852 Uncharacterised protein family UPF0251 TOLA_RS05650 0f4a1e0ef18ae69d1e62cbf875e56e13 1240 PANTHER PTHR36985 6 1240 3.7E-182 T 22-04-2016 TOLA_RS05650 0f4a1e0ef18ae69d1e62cbf875e56e13 1240 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 901 1240 6.4E-51 T 22-04-2016 IPR007452 Translocation and assembly module TamB TOLA_RS14400 a6714ad1e40da00e73cbd56e4945abd1 149 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 145 1.7E-47 T 22-04-2016 IPR003791 Protein of unknown function UPF0178 TOLA_RS14400 a6714ad1e40da00e73cbd56e4945abd1 149 PANTHER PTHR35146:SF1 1 148 1.3E-53 T 22-04-2016 TOLA_RS14400 a6714ad1e40da00e73cbd56e4945abd1 149 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 31.657 T 22-04-2016 IPR003791 Protein of unknown function UPF0178 TOLA_RS14400 a6714ad1e40da00e73cbd56e4945abd1 149 PANTHER PTHR35146 1 148 1.3E-53 T 22-04-2016 TOLA_RS07685 2d14135b7876717e3242fa6b549f7084 136 SUPERFAMILY SSF49503 40 134 1.39E-11 T 22-04-2016 IPR008972 Cupredoxin TOLA_RS07685 2d14135b7876717e3242fa6b549f7084 136 Gene3D G3DSA:2.60.40.420 39 134 4.5E-13 T 22-04-2016 IPR008972 Cupredoxin TOLA_RS13565 0554cdddb1f1d5dcc3900ff1eb7c3fdb 116 SUPERFAMILY SSF55620 1 114 2.11E-33 T 22-04-2016 TOLA_RS13565 0554cdddb1f1d5dcc3900ff1eb7c3fdb 116 SMART SM00905 4 114 6.7E-42 T 22-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS13565 0554cdddb1f1d5dcc3900ff1eb7c3fdb 116 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 114 6.4E-29 T 22-04-2016 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS13565 0554cdddb1f1d5dcc3900ff1eb7c3fdb 116 PANTHER PTHR20941 1 115 1.3E-24 T 22-04-2016 TOLA_RS13565 0554cdddb1f1d5dcc3900ff1eb7c3fdb 116 Pfam PF02152 Dihydroneopterin aldolase 4 112 1.0E-31 T 22-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS13565 0554cdddb1f1d5dcc3900ff1eb7c3fdb 116 Gene3D G3DSA:3.30.1130.10 1 115 3.1E-38 T 22-04-2016 TOLA_RS13565 0554cdddb1f1d5dcc3900ff1eb7c3fdb 116 TIGRFAM TIGR00526 folB_dom: FolB domain 1 115 4.6E-28 T 22-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 TOLA_RS10180 c5c2999196827929fd9bcee98ebd0784 178 PANTHER PTHR33204 1 160 5.9E-65 T 22-04-2016 TOLA_RS10180 c5c2999196827929fd9bcee98ebd0784 178 Gene3D G3DSA:1.10.10.10 1 105 4.7E-33 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10180 c5c2999196827929fd9bcee98ebd0784 178 SUPERFAMILY SSF46785 5 143 5.27E-36 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10180 c5c2999196827929fd9bcee98ebd0784 178 Pfam PF01638 HxlR-like helix-turn-helix 20 105 6.8E-22 T 22-04-2016 IPR002577 Helix-turn-helix, HxlR type TOLA_RS10180 c5c2999196827929fd9bcee98ebd0784 178 PANTHER PTHR33204:SF10 1 160 5.9E-65 T 22-04-2016 TOLA_RS01970 5219510d0122dd9e9596f364e13ba255 207 PANTHER PTHR30086 2 207 4.6E-74 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS01970 5219510d0122dd9e9596f364e13ba255 207 PANTHER PTHR30086:SF0 2 207 4.6E-74 T 22-04-2016 TOLA_RS01970 5219510d0122dd9e9596f364e13ba255 207 Pfam PF01810 LysE type translocator 16 201 7.7E-41 T 22-04-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 TOLA_RS02120 28eb162acb068a2778b287a53735a9c7 93 Pfam PF10115 Transcriptional activator HlyU 4 92 1.2E-38 T 22-04-2016 IPR018772 Transcription activator HlyU TOLA_RS07170 2664997f72f3aeb171d37c6451177258 71 Pfam PF03692 Putative zinc- or iron-chelating domain 25 65 3.4E-8 T 22-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein TOLA_RS05645 abe21ac5b4595f010ecf21dbbd0e3614 579 PANTHER PTHR12815 12 579 1.0E-164 T 22-04-2016 TOLA_RS05645 abe21ac5b4595f010ecf21dbbd0e3614 579 PANTHER PTHR12815:SF12 12 579 1.0E-164 T 22-04-2016 TOLA_RS05645 abe21ac5b4595f010ecf21dbbd0e3614 579 Pfam PF01103 Surface antigen 279 566 4.6E-25 T 22-04-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 TOLA_RS05645 abe21ac5b4595f010ecf21dbbd0e3614 579 Pfam PF07244 Surface antigen variable number repeat 111 191 8.0E-6 T 22-04-2016 IPR010827 Surface antigen variable number GO:0019867 TOLA_RS05645 abe21ac5b4595f010ecf21dbbd0e3614 579 Gene3D G3DSA:2.40.160.50 311 575 2.4E-14 T 22-04-2016 TOLA_RS02080 ba7664dfc9802c79eeb58d23be4bdfa8 66 SUPERFAMILY SSF47598 2 46 7.19E-8 T 22-04-2016 IPR010985 Ribbon-helix-helix GO:0006355 TOLA_RS02080 ba7664dfc9802c79eeb58d23be4bdfa8 66 Gene3D G3DSA:1.10.1220.10 2 46 2.2E-8 T 22-04-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TOLA_RS14660 ccc1ab45be9c3ced45cba45f0d1676a0 289 SUPERFAMILY SSF53448 9 263 3.6E-21 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS14660 ccc1ab45be9c3ced45cba45f0d1676a0 289 Gene3D G3DSA:3.90.550.10 48 234 2.3E-7 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS04810 5a4b239970bc3ee72c672789901b7541 98 SUPERFAMILY SSF54909 1 97 2.95E-29 T 22-04-2016 IPR011008 Dimeric alpha-beta barrel TOLA_RS04810 5a4b239970bc3ee72c672789901b7541 98 Gene3D G3DSA:3.30.70.1060 1 97 1.8E-33 T 22-04-2016 TOLA_RS04810 5a4b239970bc3ee72c672789901b7541 98 Pfam PF03795 YCII-related domain 1 94 2.1E-27 T 22-04-2016 IPR005545 YCII-related TOLA_RS04810 5a4b239970bc3ee72c672789901b7541 98 PANTHER PTHR33606 1 98 4.9E-28 T 22-04-2016 TOLA_RS07270 3c9e6b1ea3476fe9726c41de184d5efa 663 Gene3D G3DSA:3.30.230.10 415 615 1.1E-31 T 22-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TOLA_RS07270 3c9e6b1ea3476fe9726c41de184d5efa 663 PANTHER PTHR10046 330 620 7.7E-111 T 22-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 TOLA_RS07270 3c9e6b1ea3476fe9726c41de184d5efa 663 Pfam PF13654 AAA domain 144 397 1.9E-48 T 22-04-2016 TOLA_RS07270 3c9e6b1ea3476fe9726c41de184d5efa 663 PANTHER PTHR10046:SF46 330 620 7.7E-111 T 22-04-2016 TOLA_RS07270 3c9e6b1ea3476fe9726c41de184d5efa 663 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 506 525 3.6E-10 T 22-04-2016 TOLA_RS07270 3c9e6b1ea3476fe9726c41de184d5efa 663 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 536 555 3.6E-10 T 22-04-2016 TOLA_RS07270 3c9e6b1ea3476fe9726c41de184d5efa 663 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 423 439 3.6E-10 T 22-04-2016 TOLA_RS07270 3c9e6b1ea3476fe9726c41de184d5efa 663 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 566 584 3.6E-10 T 22-04-2016 TOLA_RS07270 3c9e6b1ea3476fe9726c41de184d5efa 663 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 509 614 9.1E-9 T 22-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 TOLA_RS07270 3c9e6b1ea3476fe9726c41de184d5efa 663 SUPERFAMILY SSF54211 422 616 7.97E-33 T 22-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TOLA_RS06825 59e3c1a719add058e0c97761ce0395cc 299 PANTHER PTHR32243 6 299 3.2E-80 T 22-04-2016 TOLA_RS06825 59e3c1a719add058e0c97761ce0395cc 299 Gene3D G3DSA:1.10.3720.10 13 286 5.1E-58 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06825 59e3c1a719add058e0c97761ce0395cc 299 SUPERFAMILY SSF161098 14 299 6.35E-65 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS06825 59e3c1a719add058e0c97761ce0395cc 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 284 3.3E-20 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS09095 7f1d8205971acd8564c520bc880d7f33 249 Gene3D G3DSA:3.20.20.150 1 248 2.5E-74 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS09095 7f1d8205971acd8564c520bc880d7f33 249 SUPERFAMILY SSF51658 4 248 3.02E-52 T 22-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TOLA_RS16170 86189e0ff2a8c3d64b6744bcc5a76a40 72 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 4 68 4.3E-32 T 22-04-2016 IPR024530 Putative quorum-sensing-regulated virulence factor TOLA_RS16170 86189e0ff2a8c3d64b6744bcc5a76a40 72 PANTHER PTHR40613 2 72 4.9E-36 T 22-04-2016 TOLA_RS16170 86189e0ff2a8c3d64b6744bcc5a76a40 72 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 15 68 1.0E-18 T 22-04-2016 IPR024530 Putative quorum-sensing-regulated virulence factor TOLA_RS16170 86189e0ff2a8c3d64b6744bcc5a76a40 72 PANTHER PTHR40613:SF1 2 72 4.9E-36 T 22-04-2016 TOLA_RS09840 71a9a0b498541eb4ab7a02b1147f44c0 105 SUPERFAMILY SSF47413 47 101 5.09E-8 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS09840 71a9a0b498541eb4ab7a02b1147f44c0 105 Gene3D G3DSA:1.10.260.40 47 101 1.2E-7 T 22-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 TOLA_RS09840 71a9a0b498541eb4ab7a02b1147f44c0 105 SMART SM00530 49 104 1.1E-5 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS09840 71a9a0b498541eb4ab7a02b1147f44c0 105 Pfam PF01381 Helix-turn-helix 50 101 8.1E-8 T 22-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TOLA_RS07490 cb487101221942a847037540adfae5fa 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 282 2.5E-33 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS07490 cb487101221942a847037540adfae5fa 308 PANTHER PTHR32196:SF33 10 307 2.2E-116 T 22-04-2016 TOLA_RS07490 cb487101221942a847037540adfae5fa 308 PANTHER PTHR32196 10 307 2.2E-116 T 22-04-2016 TOLA_RS02330 262343427e56b7a81f1084da6f30a5ff 146 PANTHER PTHR35603 2 144 1.7E-33 T 22-04-2016 TOLA_RS02330 262343427e56b7a81f1084da6f30a5ff 146 Pfam PF05433 Glycine zipper 2TM domain 63 104 9.3E-9 T 22-04-2016 IPR008816 Glycine zipper 2TM domain GO:0019867 TOLA_RS04750 7240585b6a66d52f7a477b23c3be31ab 343 Pfam PF04245 37-kD nucleoid-associated bacterial protein 9 332 2.4E-94 T 22-04-2016 IPR007358 Nucleoid-associated protein NdpA GO:0009295 TOLA_RS04750 7240585b6a66d52f7a477b23c3be31ab 343 PANTHER PTHR38772 2 343 3.8E-120 T 22-04-2016 TOLA_RS10030 fc031e32225a16e51f8fe249f7195d3a 326 PANTHER PTHR32196:SF21 10 326 4.3E-108 T 22-04-2016 TOLA_RS10030 fc031e32225a16e51f8fe249f7195d3a 326 PANTHER PTHR32196 10 326 4.3E-108 T 22-04-2016 TOLA_RS10030 fc031e32225a16e51f8fe249f7195d3a 326 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 318 6.5E-48 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS12355 77866340c54b474867bfaf59a07db35b 187 TIGRFAM TIGR03748 conj_PilL: integrating conjugative element protein PilL, PFGI-1 class 53 156 6.5E-42 T 22-04-2016 IPR022260 Integrating conjugative element protein PilL, PFGI-1 TOLA_RS09140 307549bad96e2b5e995704e7512d62c6 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 14 136 3.0E-27 T 22-04-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 TOLA_RS09140 307549bad96e2b5e995704e7512d62c6 139 PANTHER PTHR30558 13 137 4.3E-29 T 22-04-2016 TOLA_RS09140 307549bad96e2b5e995704e7512d62c6 139 PANTHER PTHR30558:SF3 13 137 4.3E-29 T 22-04-2016 TOLA_RS16200 6a0ee537d34a60e1f3bf9301bc25e407 322 Pfam PF03812 2-keto-3-deoxygluconate permease 6 309 1.4E-107 T 22-04-2016 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 TOLA_RS16200 6a0ee537d34a60e1f3bf9301bc25e407 322 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 29 311 1.0E-74 T 22-04-2016 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 TOLA_RS14325 205c4317901b7bf564d302d76aff62b0 261 Pfam PF01578 Cytochrome C assembly protein 36 258 5.5E-28 T 22-04-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TOLA_RS14325 205c4317901b7bf564d302d76aff62b0 261 PANTHER PTHR38034 2 261 7.0E-58 T 22-04-2016 TOLA_RS06685 1666e17dd205638b6c7855803e285af7 265 Pfam PF08867 FRG domain 23 116 1.0E-28 T 22-04-2016 IPR014966 FRG domain TOLA_RS06685 1666e17dd205638b6c7855803e285af7 265 SMART SM00901 20 126 1.3E-29 T 22-04-2016 IPR014966 FRG domain TOLA_RS03785 f663d863a60802bb9567a0b259b1707b 510 PIRSF PIRSF007056 2 510 1.1E-235 T 22-04-2016 IPR012036 Bacteriophage Mu, Gp28 TOLA_RS03785 f663d863a60802bb9567a0b259b1707b 510 Pfam PF03237 Terminase-like family 35 278 3.0E-8 T 22-04-2016 IPR004921 Terminase, large subunit TOLA_RS07335 e5ca5aa9dc7a363017d4731a66356a13 313 PANTHER PTHR40400 1 312 6.5E-93 T 22-04-2016 IPR010293 Na+-dependent bicarbonate transporter superfamily TOLA_RS07335 e5ca5aa9dc7a363017d4731a66356a13 313 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 5 306 1.7E-109 T 22-04-2016 IPR010293 Na+-dependent bicarbonate transporter superfamily TOLA_RS14350 420687db291e7acd9a2e245ca1246548 128 Gene3D G3DSA:3.40.50.10220 14 56 1.7E-4 T 22-04-2016 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS14350 420687db291e7acd9a2e245ca1246548 128 Gene3D G3DSA:3.40.50.10220 94 127 1.7E-4 T 22-04-2016 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS14350 420687db291e7acd9a2e245ca1246548 128 Pfam PF03603 DNA polymerase III psi subunit 15 125 3.6E-4 T 22-04-2016 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TOLA_RS14995 194b7928f12b0f7650044f7ab4561d0c 132 Pfam PF06295 Protein of unknown function (DUF1043) 11 127 2.5E-26 T 22-04-2016 IPR009386 Protein of unknown function DUF1043 TOLA_RS14995 194b7928f12b0f7650044f7ab4561d0c 132 PANTHER PTHR39579 1 128 7.0E-13 T 22-04-2016 TOLA_RS07105 96ba6e83d786de6d23fe86ccb3f2f6b0 349 Pfam PF00793 DAHP synthetase I family 40 336 8.6E-107 T 22-04-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 TOLA_RS07105 96ba6e83d786de6d23fe86ccb3f2f6b0 349 SUPERFAMILY SSF51569 6 347 8.69E-138 T 22-04-2016 TOLA_RS07105 96ba6e83d786de6d23fe86ccb3f2f6b0 349 Gene3D G3DSA:3.20.20.70 8 348 1.2E-157 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS07105 96ba6e83d786de6d23fe86ccb3f2f6b0 349 PANTHER PTHR21225:SF7 1 348 3.4E-253 T 22-04-2016 TOLA_RS07105 96ba6e83d786de6d23fe86ccb3f2f6b0 349 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 5 348 1.1E-172 T 22-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 TOLA_RS07105 96ba6e83d786de6d23fe86ccb3f2f6b0 349 PANTHER PTHR21225 1 348 3.4E-253 T 22-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 TOLA_RS07105 96ba6e83d786de6d23fe86ccb3f2f6b0 349 PIRSF PIRSF001361 1 349 1.8E-163 T 22-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 TOLA_RS03805 d991fd91e401655a177915ff689f7c54 144 Pfam PF05069 Phage virion morphogenesis family 17 143 1.0E-25 T 22-04-2016 IPR006522 Phage virion morphogensis protein TOLA_RS03805 d991fd91e401655a177915ff689f7c54 144 TIGRFAM TIGR01635 tail_comp_S: phage virion morphogenesis protein 30 143 2.7E-13 T 22-04-2016 IPR006522 Phage virion morphogensis protein TOLA_RS06045 7e0fb08668c5f827e80c5051301054d0 469 Pfam PF03235 Protein of unknown function DUF262 13 196 1.4E-27 T 22-04-2016 IPR004919 Domain of unknown function DUF262 TOLA_RS06045 7e0fb08668c5f827e80c5051301054d0 469 PANTHER PTHR35149:SF2 1 219 2.3E-21 T 22-04-2016 TOLA_RS06045 7e0fb08668c5f827e80c5051301054d0 469 PANTHER PTHR35149 1 219 2.3E-21 T 22-04-2016 TOLA_RS12385 f9e52d81df0370890fbbfffb6428fb31 249 Pfam PF14348 Domain of unknown function (DUF4400) 51 246 3.0E-76 T 22-04-2016 IPR022266 Integrating conjugative element protein, PFL4697-type TOLA_RS12385 f9e52d81df0370890fbbfffb6428fb31 249 TIGRFAM TIGR03747 conj_TIGR03747: integrating conjugative element membrane protein, PFL_4697 family 15 249 1.9E-100 T 22-04-2016 IPR022266 Integrating conjugative element protein, PFL4697-type TOLA_RS08985 b34ac2c645e0a81ab34a5a1773ddfbba 159 Pfam PF13577 SnoaL-like domain 7 136 4.5E-24 T 22-04-2016 IPR009959 Polyketide cyclase SnoaL-like domain TOLA_RS08985 b34ac2c645e0a81ab34a5a1773ddfbba 159 Gene3D G3DSA:3.10.450.50 8 145 2.3E-29 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS08985 b34ac2c645e0a81ab34a5a1773ddfbba 159 SUPERFAMILY SSF54427 4 147 6.64E-33 T 22-04-2016 IPR032710 NTF2-like domain TOLA_RS02505 681ebdd7434ce059d751fee5f8f9a08c 376 Pfam PF13609 Gram-negative porin 6 357 2.7E-22 T 22-04-2016 TOLA_RS02505 681ebdd7434ce059d751fee5f8f9a08c 376 SUPERFAMILY SSF56935 20 373 6.41E-41 T 22-04-2016 TOLA_RS02505 681ebdd7434ce059d751fee5f8f9a08c 376 PANTHER PTHR34501 1 95 9.2E-47 T 22-04-2016 TOLA_RS02505 681ebdd7434ce059d751fee5f8f9a08c 376 PANTHER PTHR34501 117 376 9.2E-47 T 22-04-2016 TOLA_RS02505 681ebdd7434ce059d751fee5f8f9a08c 376 Gene3D G3DSA:2.40.160.10 20 376 2.6E-54 T 22-04-2016 IPR023614 Porin domain TOLA_RS01555 6959d1ef991ad710987a3bd4c8eb085d 303 SUPERFAMILY SSF103481 205 287 1.28E-12 T 22-04-2016 TOLA_RS01555 6959d1ef991ad710987a3bd4c8eb085d 303 SUPERFAMILY SSF103481 42 134 6.93E-9 T 22-04-2016 TOLA_RS01555 6959d1ef991ad710987a3bd4c8eb085d 303 PANTHER PTHR32322:SF9 3 301 7.4E-79 T 22-04-2016 TOLA_RS01555 6959d1ef991ad710987a3bd4c8eb085d 303 Pfam PF00892 EamA-like transporter family 142 284 5.4E-18 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS01555 6959d1ef991ad710987a3bd4c8eb085d 303 Pfam PF00892 EamA-like transporter family 8 131 2.9E-12 T 22-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 TOLA_RS01555 6959d1ef991ad710987a3bd4c8eb085d 303 PANTHER PTHR32322 3 301 7.4E-79 T 22-04-2016 TOLA_RS03335 f4798056ba293cadcfd2849c3ca8e29d 255 SUPERFAMILY SSF49899 35 239 5.45E-7 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain TOLA_RS03335 f4798056ba293cadcfd2849c3ca8e29d 255 Gene3D G3DSA:2.60.120.200 33 231 1.1E-4 T 22-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain TOLA_RS06865 2a5b95284599bf1bf5fd0ae768968599 134 Pfam PF11042 Protein of unknown function (DUF2750) 22 123 7.5E-34 T 22-04-2016 IPR021284 Protein of unknown function DUF2750 TOLA_RS16110 f4b1a93ba3e803cbd33cbfc5d4e62d1b 129 Pfam PF03899 ATP synthase I chain 16 112 2.0E-11 T 22-04-2016 IPR005598 ATP synthase protein I TOLA_RS05745 a9964bfd0f5ca795eae2897d2b7c4d4a 132 PANTHER PTHR30574 2 132 5.4E-21 T 22-04-2016 TOLA_RS05745 a9964bfd0f5ca795eae2897d2b7c4d4a 132 PANTHER PTHR30574:SF1 2 132 5.4E-21 T 22-04-2016 TOLA_RS05745 a9964bfd0f5ca795eae2897d2b7c4d4a 132 Pfam PF04143 Sulphur transport 6 126 1.1E-8 T 22-04-2016 IPR007272 Sulphur transport domain TOLA_RS09860 308fc52753a1c2899c72f96f7eac4606 102 Pfam PF11604 Copper binding periplasmic protein CusF 32 87 8.2E-13 T 22-04-2016 IPR021647 Copper binding periplasmic protein CusF TOLA_RS07410 a326bddfdb07451cec1186e4410490fa 171 Pfam PF01863 Protein of unknown function DUF45 74 149 1.6E-8 T 22-04-2016 IPR002725 Protein of unknown function DUF45 TOLA_RS07410 a326bddfdb07451cec1186e4410490fa 171 PANTHER PTHR30399:SF4 1 163 3.3E-80 T 22-04-2016 TOLA_RS07410 a326bddfdb07451cec1186e4410490fa 171 PANTHER PTHR30399 1 163 3.3E-80 T 22-04-2016 TOLA_RS07455 279099e92eb1c314754d605fdca1443e 240 Pfam PF04288 MukE-like family 11 235 2.0E-117 T 22-04-2016 IPR007385 Prokaryotic chromosome segregation/condensation protein MukE GO:0005737|GO:0007059|GO:0030261 TOLA_RS09650 f552d9c954ed499cf6206f13f49e954b 349 PANTHER PTHR30505:SF0 6 312 1.8E-98 T 22-04-2016 TOLA_RS09650 f552d9c954ed499cf6206f13f49e954b 349 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 6 340 2.4E-87 T 22-04-2016 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 TOLA_RS09650 f552d9c954ed499cf6206f13f49e954b 349 PANTHER PTHR30505 6 312 1.8E-98 T 22-04-2016 TOLA_RS05980 c677529ef36899680bae2faf29951701 269 Pfam PF11726 Protein of unknown function (DUF3296) 76 267 4.9E-70 T 22-04-2016 IPR021723 Inovirus Gp2 TOLA_RS11215 d96620ad516ea732ccd6751e6df15d29 123 PANTHER PTHR33931 3 123 2.8E-28 T 22-04-2016 TOLA_RS11215 d96620ad516ea732ccd6751e6df15d29 123 PANTHER PTHR33931:SF2 3 123 2.8E-28 T 22-04-2016 TOLA_RS11215 d96620ad516ea732ccd6751e6df15d29 123 Pfam PF03788 LrgA family 27 117 5.3E-23 T 22-04-2016 IPR005538 LrgA/CidA family GO:0016021 TOLA_RS15755 8aee6e07558550c221f8809c80ac905a 214 SUPERFAMILY SSF51366 1 214 6.65E-37 T 22-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TOLA_RS15755 8aee6e07558550c221f8809c80ac905a 214 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 5 201 3.7E-30 T 22-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS15755 8aee6e07558550c221f8809c80ac905a 214 PANTHER PTHR35039 1 214 4.0E-96 T 22-04-2016 TOLA_RS15755 8aee6e07558550c221f8809c80ac905a 214 PANTHER PTHR35039:SF2 1 214 4.0E-96 T 22-04-2016 TOLA_RS15755 8aee6e07558550c221f8809c80ac905a 214 Gene3D G3DSA:3.20.20.70 1 214 1.8E-73 T 22-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TOLA_RS15755 8aee6e07558550c221f8809c80ac905a 214 SMART SM00934 5 206 8.0E-29 T 22-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 TOLA_RS04485 296f9f5a364da391b37d3215d7c370fb 811 Pfam PF02687 FtsX-like permease family 249 362 6.4E-12 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 TOLA_RS04485 296f9f5a364da391b37d3215d7c370fb 811 Pfam PF02687 FtsX-like permease family 690 800 8.4E-7 T 22-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 TOLA_RS04485 296f9f5a364da391b37d3215d7c370fb 811 PANTHER PTHR30287 1 802 2.5E-108 T 22-04-2016 TOLA_RS00170 f7534613fc5279b9407899762e8ff522 261 PANTHER PTHR10859:SF99 7 130 5.1E-26 T 22-04-2016 TOLA_RS00170 f7534613fc5279b9407899762e8ff522 261 PANTHER PTHR10859 7 130 5.1E-26 T 22-04-2016 TOLA_RS00170 f7534613fc5279b9407899762e8ff522 261 Gene3D G3DSA:3.90.550.10 2 104 5.3E-14 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS00170 f7534613fc5279b9407899762e8ff522 261 SUPERFAMILY SSF53448 4 151 1.22E-25 T 22-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases TOLA_RS00170 f7534613fc5279b9407899762e8ff522 261 Pfam PF00535 Glycosyl transferase family 2 8 128 2.8E-17 T 22-04-2016 IPR001173 Glycosyltransferase 2-like TOLA_RS08045 eb46725a345f80b8216b76db0113dd54 238 PANTHER PTHR30450:SF5 1 237 1.0E-159 T 22-04-2016 TOLA_RS08045 eb46725a345f80b8216b76db0113dd54 238 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 227 1.1E-11 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08045 eb46725a345f80b8216b76db0113dd54 238 Gene3D G3DSA:1.10.3720.10 20 228 1.8E-35 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08045 eb46725a345f80b8216b76db0113dd54 238 SUPERFAMILY SSF161098 17 220 8.63E-34 T 22-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TOLA_RS08045 eb46725a345f80b8216b76db0113dd54 238 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 21 121 2.7E-12 T 22-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 TOLA_RS08045 eb46725a345f80b8216b76db0113dd54 238 PANTHER PTHR30450 1 237 1.0E-159 T 22-04-2016 TOLA_RS12770 e7afb66fa0b6ce7342b9a1cca4d2de74 311 PANTHER PTHR31752:SF13 98 311 1.0E-50 T 22-04-2016 TOLA_RS12770 e7afb66fa0b6ce7342b9a1cca4d2de74 311 Pfam PF03547 Membrane transport protein 13 150 6.2E-12 T 22-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 TOLA_RS12770 e7afb66fa0b6ce7342b9a1cca4d2de74 311 Pfam PF03547 Membrane transport protein 167 305 1.1E-19 T 22-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 TOLA_RS12770 e7afb66fa0b6ce7342b9a1cca4d2de74 311 PANTHER PTHR31752 98 311 1.0E-50 T 22-04-2016 TOLA_RS10555 1838c7dc5aef0df163efa149d9a14ea4 383 TIGRFAM TIGR00843 benE: benzoate transporter 9 377 7.8E-121 T 22-04-2016 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 TOLA_RS10555 1838c7dc5aef0df163efa149d9a14ea4 383 PANTHER PTHR30199 1 378 2.6E-137 T 22-04-2016 TOLA_RS10555 1838c7dc5aef0df163efa149d9a14ea4 383 Pfam PF03594 Benzoate membrane transport protein 3 377 1.2E-137 T 22-04-2016 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 TOLA_RS10555 1838c7dc5aef0df163efa149d9a14ea4 383 PANTHER PTHR30199:SF0 1 378 2.6E-137 T 22-04-2016 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 TOLA_RS00395 25bd31b6b311ca793e9e7edabb0fd621 404 Pfam PF11692 Protein of unknown function (DUF3289) 210 401 2.9E-44 T 22-04-2016 IPR017483 Conserved hypothetical protein CHP03034 TOLA_RS00395 25bd31b6b311ca793e9e7edabb0fd621 404 Pfam PF11692 Protein of unknown function (DUF3289) 155 190 1.1E-6 T 22-04-2016 IPR017483 Conserved hypothetical protein CHP03034 TOLA_RS08910 01075e9140826fe8070725f1be85749d 863 Gene3D G3DSA:1.10.530.40 737 856 9.5E-10 T 22-04-2016 IPR023347 Lysozyme domain GO:0003796 TOLA_RS08910 01075e9140826fe8070725f1be85749d 863 Gene3D G3DSA:1.10.530.40 660 695 9.5E-10 T 22-04-2016 IPR023347 Lysozyme domain GO:0003796 TOLA_RS08910 01075e9140826fe8070725f1be85749d 863 SUPERFAMILY SSF53955 665 856 2.05E-9 T 22-04-2016 IPR023346 Lysozyme-like domain TOLA_RS15770 1ef1eb3c5caa12f5d807ff97cd63702c 339 Pfam PF13565 Homeodomain-like domain 55 135 2.5E-10 T 22-04-2016 TOLA_RS15770 1ef1eb3c5caa12f5d807ff97cd63702c 339 SUPERFAMILY SSF46689 17 139 8.24E-10 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS15770 1ef1eb3c5caa12f5d807ff97cd63702c 339 Pfam PF13358 DDE superfamily endonuclease 176 312 1.0E-26 T 22-04-2016 TOLA_RS00690 abdea4b8c777729196a854dcb98006d4 127 PIRSF PIRSF029543 1 127 4.3E-29 T 22-04-2016 IPR016924 Uncharacterised conserved protein UCP029543 TOLA_RS03780 f38a778600c246df5d3712c66ff2a6ea 191 Pfam PF11985 Protein of unknown function (DUF3486) 7 189 1.8E-56 T 22-04-2016 IPR021874 Bacteriophage Mu, Gp27 TOLA_RS10585 0a6323e90c06dc19fde752fb39cbdd80 109 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 12 107 6.6E-39 T 22-04-2016 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 TOLA_RS10585 0a6323e90c06dc19fde752fb39cbdd80 109 PANTHER PTHR36835 1 109 1.1E-41 T 22-04-2016 TOLA_RS10585 0a6323e90c06dc19fde752fb39cbdd80 109 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 19 92 3.2E-19 T 22-04-2016 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 TOLA_RS00800 934d67ec9405db029e622ad202a9e25d 374 SUPERFAMILY SSF102405 86 293 2.04E-38 T 22-04-2016 TOLA_RS00800 934d67ec9405db029e622ad202a9e25d 374 PANTHER PTHR32039:SF8 73 374 1.0E-103 T 22-04-2016 TOLA_RS00800 934d67ec9405db029e622ad202a9e25d 374 Gene3D G3DSA:3.40.50.450 118 265 1.8E-12 T 22-04-2016 TOLA_RS00800 934d67ec9405db029e622ad202a9e25d 374 PANTHER PTHR32039 73 374 1.0E-103 T 22-04-2016 TOLA_RS00800 934d67ec9405db029e622ad202a9e25d 374 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 76 292 1.1E-78 T 22-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 TOLA_RS00800 934d67ec9405db029e622ad202a9e25d 374 Pfam PF02481 DNA recombination-mediator protein A 84 284 6.5E-79 T 22-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 TOLA_RS13965 6101e134d990c81bc78158c97d88e76f 171 SUPERFAMILY SSF142433 12 169 7.72E-56 T 22-04-2016 IPR008136 CinA, C-terminal TOLA_RS13965 6101e134d990c81bc78158c97d88e76f 171 Pfam PF02464 Competence-damaged protein 17 167 1.2E-58 T 22-04-2016 IPR008136 CinA, C-terminal TOLA_RS13965 6101e134d990c81bc78158c97d88e76f 171 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 22 166 1.2E-53 T 22-04-2016 IPR008136 CinA, C-terminal TOLA_RS13965 6101e134d990c81bc78158c97d88e76f 171 PANTHER PTHR13939 14 167 1.2E-66 T 22-04-2016 TOLA_RS13965 6101e134d990c81bc78158c97d88e76f 171 Gene3D G3DSA:3.90.950.20 10 169 1.4E-57 T 22-04-2016 IPR008136 CinA, C-terminal TOLA_RS10935 54e63d0452f722450059c0a3a4b7c096 104 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 4 101 1.6E-28 T 22-04-2016 IPR008407 Branched-chain amino acid transport, AzlD TOLA_RS01175 47b294bd4e32e6f6d8c997ac311b3ab6 152 Pfam PF11042 Protein of unknown function (DUF2750) 41 141 1.0E-32 T 22-04-2016 IPR021284 Protein of unknown function DUF2750 TOLA_RS05985 947d7a7deaaa6dec5da3224581fff2a0 478 Pfam PF13148 Protein of unknown function (DUF3987) 31 385 2.3E-102 T 22-04-2016 IPR025048 Protein of unknown function DUF3987) TOLA_RS14430 94e916ffa71ec71a0137cd41e2237e2e 170 PANTHER PTHR35335:SF1 2 167 2.0E-30 T 22-04-2016 TOLA_RS14430 94e916ffa71ec71a0137cd41e2237e2e 170 Pfam PF04186 FxsA cytoplasmic membrane protein 8 112 1.8E-30 T 22-04-2016 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 TOLA_RS14430 94e916ffa71ec71a0137cd41e2237e2e 170 PANTHER PTHR35335 2 167 2.0E-30 T 22-04-2016 TOLA_RS03620 d19fe422644016ad229d25779019e3fe 114 SUPERFAMILY SSF46689 12 107 7.7E-19 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS03620 d19fe422644016ad229d25779019e3fe 114 Pfam PF01527 Transposase 12 88 2.8E-16 T 22-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 TOLA_RS03620 d19fe422644016ad229d25779019e3fe 114 Gene3D G3DSA:1.10.10.60 14 101 2.9E-17 T 22-04-2016 IPR009057 Homeodomain-like GO:0003677 TOLA_RS03620 d19fe422644016ad229d25779019e3fe 114 PANTHER PTHR33215 8 113 1.0E-22 T 22-04-2016 TOLA_RS11570 89adefcfa1240fb52e78e7aacc4ea48d 316 Pfam PF06067 Domain of unknown function (DUF932) 75 296 4.1E-76 T 22-04-2016 IPR026325 Protein of unknown function DUF932 TOLA_RS11570 89adefcfa1240fb52e78e7aacc4ea48d 316 TIGRFAM TIGR03299 LGT_TIGR03299: phage/plasmid-like protein TIGR03299 7 312 3.1E-112 T 22-04-2016 IPR017686 Phage/plasmid-like protein TOLA_RS01740 54e7df300baf272aa45343729b212a42 127 SUPERFAMILY SSF47473 31 103 3.98E-12 T 22-04-2016 IPR011992 EF-hand domain pair TOLA_RS01740 54e7df300baf272aa45343729b212a42 127 ProSitePatterns PS00018 EF-hand calcium-binding domain. 40 52 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site TOLA_RS01740 54e7df300baf272aa45343729b212a42 127 Gene3D G3DSA:1.10.238.10 30 95 3.3E-10 T 22-04-2016 IPR011992 EF-hand domain pair TOLA_RS01740 54e7df300baf272aa45343729b212a42 127 SMART SM00054 71 99 15.0 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 TOLA_RS01740 54e7df300baf272aa45343729b212a42 127 SMART SM00054 31 59 0.078 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 TOLA_RS01740 54e7df300baf272aa45343729b212a42 127 Pfam PF13202 EF hand 35 55 2.1E-4 T 22-04-2016 IPR002048 EF-hand domain GO:0005509 TOLA_RS14720 9969b5d1bf31a9d743216324519c3f09 81 Pfam PF07362 Post-segregation antitoxin CcdA 11 81 2.2E-29 T 22-04-2016 IPR009956 Post-segregation antitoxin CcdA TOLA_RS03630 2098b253d43e553eb1643129d339440d 116 Gene3D G3DSA:1.10.10.10 11 67 4.8E-4 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS05700 cb30814fe169e3f78da108215aece2ec 317 PIRSF PIRSF037004 1 317 3.1E-132 T 22-04-2016 IPR017087 Uncharacterised conserved protein UCP037004 TOLA_RS05700 cb30814fe169e3f78da108215aece2ec 317 Pfam PF08349 Protein of unknown function (DUF1722) 192 308 1.2E-43 T 22-04-2016 IPR013560 Domain of unknown function DUF1722 TOLA_RS05700 cb30814fe169e3f78da108215aece2ec 317 PANTHER PTHR30087 1 317 8.3E-135 T 22-04-2016 TOLA_RS05700 cb30814fe169e3f78da108215aece2ec 317 PANTHER PTHR30087:SF0 1 317 8.3E-135 T 22-04-2016 TOLA_RS05700 cb30814fe169e3f78da108215aece2ec 317 Pfam PF04463 Protein of unknown function (DUF523) 11 149 3.4E-36 T 22-04-2016 IPR007553 Domain of unknown function DUF523 TOLA_RS14805 3bb69d1e1c0ad1a865a03bf403377902 429 Pfam PF03573 outer membrane porin, OprD family 38 394 4.0E-14 T 22-04-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 TOLA_RS14805 3bb69d1e1c0ad1a865a03bf403377902 429 Gene3D G3DSA:2.40.160.10 40 428 3.2E-27 T 22-04-2016 IPR023614 Porin domain TOLA_RS14805 3bb69d1e1c0ad1a865a03bf403377902 429 SUPERFAMILY SSF56935 107 360 5.04E-8 T 22-04-2016 TOLA_RS01610 83da7bb4b58cc4e9825e2d4b05acf36e 505 Pfam PF15978 Tn7-like transposition protein D 303 446 7.5E-20 T 22-04-2016 IPR032750 Transposon Tn7 transposition protein TnsD, C-termianl TOLA_RS01610 83da7bb4b58cc4e9825e2d4b05acf36e 505 Pfam PF06527 TniQ 4 157 1.4E-17 T 22-04-2016 IPR009492 TniQ TOLA_RS14755 8bfe6c49589cfa7598f34f009ff4f430 69 Pfam PF09722 Protein of unknown function (DUF2384) 15 66 7.1E-13 T 22-04-2016 IPR024467 Domain of unknown function DUF2384 TOLA_RS03625 a58934912f819032d6d1115543576daf 343 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 75 254 7.9E-22 T 22-04-2016 IPR000477 Reverse transcriptase domain TOLA_RS03625 a58934912f819032d6d1115543576daf 343 SUPERFAMILY SSF56672 54 252 7.56E-13 T 22-04-2016 TOLA_RS03625 a58934912f819032d6d1115543576daf 343 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 211 222 2.4E-31 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 TOLA_RS03625 a58934912f819032d6d1115543576daf 343 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 115 129 2.4E-31 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 TOLA_RS03625 a58934912f819032d6d1115543576daf 343 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 178 191 2.4E-31 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 TOLA_RS03625 a58934912f819032d6d1115543576daf 343 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 261 267 2.4E-31 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 TOLA_RS03625 a58934912f819032d6d1115543576daf 343 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 70 83 2.4E-31 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 TOLA_RS03625 a58934912f819032d6d1115543576daf 343 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 131 149 2.4E-31 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 TOLA_RS03625 a58934912f819032d6d1115543576daf 343 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 196 209 2.4E-31 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 TOLA_RS03625 a58934912f819032d6d1115543576daf 343 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 84 96 2.4E-31 T 22-04-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 TOLA_RS15550 26947b146ae4e78603c1905a09d7a60a 153 PANTHER PTHR30087:SF1 1 147 6.1E-48 T 22-04-2016 TOLA_RS15550 26947b146ae4e78603c1905a09d7a60a 153 Pfam PF04463 Protein of unknown function (DUF523) 7 143 2.0E-44 T 22-04-2016 IPR007553 Domain of unknown function DUF523 TOLA_RS15550 26947b146ae4e78603c1905a09d7a60a 153 PANTHER PTHR30087 1 147 6.1E-48 T 22-04-2016 TOLA_RS14615 1ae30295478406eae8f1cf15e139e7c0 154 SUPERFAMILY SSF54611 108 152 4.58E-7 T 22-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TOLA_RS14615 1ae30295478406eae8f1cf15e139e7c0 154 Gene3D G3DSA:3.10.420.10 93 151 1.5E-4 T 22-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 TOLA_RS08235 4d12787c5e2a3d9374a04df7978fcd28 184 Pfam PF04955 HupE / UreJ protein 11 176 1.3E-28 T 22-04-2016 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein TOLA_RS08235 4d12787c5e2a3d9374a04df7978fcd28 184 PIRSF PIRSF016919 1 184 2.6E-29 T 22-04-2016 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein TOLA_RS12220 4cc548cb1f9fff5f539086eff512fce8 262 TIGRFAM TIGR03761 ICE_PFL4669: integrating conjugative element protein, PFL_4669 family 16 228 4.3E-88 T 22-04-2016 IPR014996 Integrating conjugative element protein, PFL4669 TOLA_RS12220 4cc548cb1f9fff5f539086eff512fce8 262 Pfam PF08900 Domain of unknown function (DUF1845) 15 225 1.8E-80 T 22-04-2016 IPR014996 Integrating conjugative element protein, PFL4669 TOLA_RS07770 e84ddd2bf123207ef06ac9c1ad086dd7 206 Gene3D G3DSA:1.10.3210.10 11 201 4.1E-18 T 22-04-2016 IPR006674 HD domain TOLA_RS07770 e84ddd2bf123207ef06ac9c1ad086dd7 206 SUPERFAMILY SSF109604 10 201 7.71E-30 T 22-04-2016 TOLA_RS15605 92d679f71d5a9a919647392b9501439f 299 Pfam PF08378 Nuclease-related domain 129 244 6.6E-20 T 22-04-2016 IPR011528 Nuclease-related domain, NERD TOLA_RS07475 8c204fe955fe25dc36e3731deed19725 308 Gene3D G3DSA:1.10.10.10 40 69 3.6E-4 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS06750 343db43d69abc34631c6eae22c117a9a 451 PANTHER PTHR30563 48 446 3.3E-89 T 22-04-2016 TOLA_RS06750 343db43d69abc34631c6eae22c117a9a 451 Pfam PF02646 RmuC family 137 432 8.6E-94 T 22-04-2016 IPR003798 DNA recombination RmuC TOLA_RS00715 2ce4a6f011a1619d683fff11e77e1d92 306 PANTHER PTHR11795 1 306 1.8E-136 T 22-04-2016 TOLA_RS00715 2ce4a6f011a1619d683fff11e77e1d92 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 290 3.9E-59 T 22-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TOLA_RS00715 2ce4a6f011a1619d683fff11e77e1d92 306 PANTHER PTHR11795:SF371 1 306 1.8E-136 T 22-04-2016 TOLA_RS01305 c6681ea5456b03ac3576630a33a22900 118 Pfam PF06923 Glucitol operon activator protein (GutM) 6 111 9.1E-31 T 22-04-2016 IPR009693 Glucitol operon activator TOLA_RS06470 2ca6fa1e4a4a77c42719e1557f28b137 1174 ProSitePatterns PS00018 EF-hand calcium-binding domain. 191 203 - T 22-04-2016 IPR018247 EF-Hand 1, calcium-binding site TOLA_RS06470 2ca6fa1e4a4a77c42719e1557f28b137 1174 Pfam PF12245 Bacterial Ig-like domain (group 3) 474 491 1.7 T 22-04-2016 IPR022038 Bacterial Ig-like domain TOLA_RS06470 2ca6fa1e4a4a77c42719e1557f28b137 1174 Pfam PF12245 Bacterial Ig-like domain (group 3) 366 383 1.6 T 22-04-2016 IPR022038 Bacterial Ig-like domain TOLA_RS06470 2ca6fa1e4a4a77c42719e1557f28b137 1174 Pfam PF12245 Bacterial Ig-like domain (group 3) 260 275 3.3 T 22-04-2016 IPR022038 Bacterial Ig-like domain TOLA_RS08230 2cf2b4aa354dc162abd829ac596312f1 231 Pfam PF01730 UreF 45 188 2.1E-30 T 22-04-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 TOLA_RS08230 2cf2b4aa354dc162abd829ac596312f1 231 Hamap MF_01385 Urease accessory protein UreF [ureF]. 13 231 28.485 T 22-04-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 TOLA_RS08230 2cf2b4aa354dc162abd829ac596312f1 231 PANTHER PTHR33620 10 231 6.8E-23 T 22-04-2016 TOLA_RS08230 2cf2b4aa354dc162abd829ac596312f1 231 PIRSF PIRSF009467 11 231 1.1E-57 T 22-04-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 TOLA_RS04980 c6b166af8e947ca173f4bdb34a8da70c 260 PANTHER PTHR30283:SF3 2 254 2.5E-113 T 22-04-2016 TOLA_RS04980 c6b166af8e947ca173f4bdb34a8da70c 260 PANTHER PTHR30283 2 254 2.5E-113 T 22-04-2016 TOLA_RS04980 c6b166af8e947ca173f4bdb34a8da70c 260 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 36.936 T 22-04-2016 IPR005583 Peroxide stress protein YaaA TOLA_RS04980 c6b166af8e947ca173f4bdb34a8da70c 260 Pfam PF03883 Protein of unknown function (DUF328) 1 243 2.8E-88 T 22-04-2016 IPR005583 Peroxide stress protein YaaA TOLA_RS03320 096dece2c14b412208681f7ec72bf541 448 Gene3D G3DSA:3.30.40.10 201 257 7.8E-4 T 22-04-2016 IPR013083 Zinc finger, RING/FYVE/PHD-type TOLA_RS03320 096dece2c14b412208681f7ec72bf541 448 Pfam PF00990 Diguanylate cyclase, GGDEF domain 329 408 1.4E-4 T 22-04-2016 IPR000160 GGDEF domain TOLA_RS10940 7723fa992a80bbc3d665f8b1f7d9dd48 248 PANTHER PTHR34979 6 244 6.2E-44 T 22-04-2016 TOLA_RS10940 7723fa992a80bbc3d665f8b1f7d9dd48 248 Pfam PF03591 AzlC protein 34 175 5.8E-41 T 22-04-2016 IPR011606 Branched-chain amino acid transport, permease TOLA_RS03870 cd2de5350ac2539d901fa2610d828bec 127 SUPERFAMILY SSF117074 34 107 2.48E-7 T 22-04-2016 TOLA_RS03870 cd2de5350ac2539d901fa2610d828bec 127 Gene3D G3DSA:2.60.40.10 53 109 7.5E-5 T 22-04-2016 IPR013783 Immunoglobulin-like fold TOLA_RS07405 fbdae1c7328231d0d27b32f3cbde91ea 117 Pfam PF11042 Protein of unknown function (DUF2750) 11 113 3.4E-33 T 22-04-2016 IPR021284 Protein of unknown function DUF2750 TOLA_RS14705 ee8d1643e028345719fe04258a708cb1 73 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 4 64 3.9E-17 T 22-04-2016 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system TOLA_RS12480 4740bd21e9d3c7e1ad30f5ff0ec10da0 152 Pfam PF11663 Toxin with endonuclease activity, of toxin-antitoxin system 8 144 2.3E-57 T 22-04-2016 IPR021679 Toxin endonuclease, YhaV TOLA_RS10895 4eb2c8df78a6ba57dddc59f237c1078b 80 SUPERFAMILY SSF46785 1 69 3.67E-18 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10895 4eb2c8df78a6ba57dddc59f237c1078b 80 Gene3D G3DSA:1.10.10.10 4 37 7.0E-4 T 22-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TOLA_RS10895 4eb2c8df78a6ba57dddc59f237c1078b 80 Pfam PF09012 FeoC like transcriptional regulator 2 67 4.7E-19 T 22-04-2016 IPR015102 Transcriptional regulator HTH-type, FeoC TOLA_RS03275 f883a079285a694a5b16049d67c39cec 185 Pfam PF07273 Protein of unknown function (DUF1439) 21 173 5.2E-43 T 22-04-2016 IPR010835 Protein of unknown function DUF1439 TOLA_RS14145 23a1ad4b2f919f9c933270f5c0dd0b49 160 Pfam PF10973 Protein of unknown function (DUF2799) 10 92 9.8E-20 T 22-04-2016 IPR021242 Protein of unknown function DUF2799 TOLA_RS05440 6650e752cac4299d9da0f4a402c81d88 198 Gene3D G3DSA:3.30.420.10 34 191 3.8E-36 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS05440 6650e752cac4299d9da0f4a402c81d88 198 Pfam PF00665 Integrase core domain 38 152 1.5E-30 T 22-04-2016 IPR001584 Integrase, catalytic core GO:0015074 TOLA_RS05440 6650e752cac4299d9da0f4a402c81d88 198 SUPERFAMILY SSF53098 34 195 1.2E-40 T 22-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TOLA_RS05440 6650e752cac4299d9da0f4a402c81d88 198 PANTHER PTHR32552 1 198 1.4E-39 T 22-04-2016 TOLA_RS03695 33538b68f088ebc64c8be9cb11b1e2a4 205 Pfam PF11363 Protein of unknown function (DUF3164) 13 203 4.9E-81 T 22-04-2016 IPR021505 Bacteriophage B3, Orf6 TOLA_RS05810 4f2f72c3f71acde9be4cc01a1f59368c 81 Pfam PF10692 Protein of unknown function (DUF2498) 4 80 2.8E-39 T 22-04-2016 IPR019633 Protein of unknown function DUF2498 TOLA_RS10870 5f8bba90b6fb6d71e3e41ea7dcae1446 109 Pfam PF04219 Protein of unknown function, DUF 8 95 6.6E-33 T 22-04-2016 IPR007335 Protein of unknown function DUF413 TOLA_RS03430 b089cc6d4b54f655c4ea6b941f2c17f4 260 Pfam PF11331 Probable zinc-ribbon domain 224 257 1.2E-4 T 22-04-2016 IPR021480 Probable zinc-ribbon domain, plant TOLA_RS08115 9407e28b72222e580b3056b1ce10031b 145 TIGRFAM TIGR04062 dnd_assoc_4: dnd system-associated protein 4 3 139 3.6E-30 T 22-04-2016 IPR023983 DNA sulphur modification system-associated protein 4 TOLA_RS02090 02bfb4fc78624c8333736b4742f4f17c 74 Pfam PF06568 Domain of unknown function (DUF1127) 32 63 7.9E-12 T 22-04-2016 IPR009506 Protein of unknown function DUF1127 TOLA_RS13055 b36e6f614341fd8167aa976d9bcf8457 61 Pfam PF11127 Protein of unknown function (DUF2892) 2 56 1.3E-15 T 22-04-2016 IPR021309 Protein of unknown function DUF2892 TOLA_RS07180 29ea7e445b70fe97a253d23d528b961b 127 Pfam PF02656 Domain of unknown function (DUF202) 9 87 2.0E-15 T 22-04-2016 IPR003807 Domain of unknown function DUF202 TOLA_RS12225 c788babaeffde26113d31b68ca627be0 176 Pfam PF11358 Protein of unknown function (DUF3158) 12 166 2.2E-74 T 22-04-2016 IPR021502 Protein of unknown function DUF3158 TOLA_RS03820 dbb52948bd81547e13439f6e8306c48f 101 SUPERFAMILY SSF160059 2 64 2.03E-13 T 22-04-2016 TOLA_RS15285 4c60afca33063f58c7a06e0814f932fd 84 PANTHER PTHR38040:SF1 2 82 1.5E-31 T 22-04-2016 TOLA_RS15285 4c60afca33063f58c7a06e0814f932fd 84 Pfam PF04380 Membrane fusogenic activity 1 78 2.1E-28 T 22-04-2016 IPR007475 Membrane fusogenic activity TOLA_RS15285 4c60afca33063f58c7a06e0814f932fd 84 PANTHER PTHR38040 2 82 1.5E-31 T 22-04-2016 TOLA_RS04510 de63f4f1425d8e0cbd27e9e49dfe1e8c 140 Pfam PF04217 Protein of unknown function, DUF412 6 138 3.3E-46 T 22-04-2016 IPR007334 Uncharacterised protein family UPF0208 TOLA_RS03725 3b0b65456898d6e4524613f418ac9d46 59 Gene3D G3DSA:1.20.5.170 36 56 3.5E-4 T 22-04-2016 TOLA_RS07260 32c50333e1902e2fbd5b29146c8979ea 570 Pfam PF11949 Protein of unknown function (DUF3466) 189 507 4.1E-34 T 22-04-2016 IPR022562 Protein of unknown function DUF3466 TOLA_RS02985 ace29e86086f2039968e21365d76252d 270 Pfam PF07357 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) 19 267 1.0E-86 T 22-04-2016 IPR009953 Dinitrogenase reductase ADP-ribosyltransferase TOLA_RS10915 ea1016f2ce6ecd45da3cf5a74cc774de 154 Pfam PF14267 Domain of unknown function (DUF4357) 93 146 1.5E-19 T 22-04-2016 IPR025579 Domain of unknown function DUF4357 TOLA_RS15810 58e8b3967cbb3e52b0c0c83782a40bbd 243 Pfam PF07603 Protein of unknown function (DUF1566) 96 240 2.7E-32 T 22-04-2016 IPR011460 Protein of unknown function DUF1566 TOLA_RS06945 0fb0d14858697bc84f995d309a688ab0 438 Pfam PF09611 CRISPR-associated protein (Cas_Csy1) 61 420 3.1E-124 T 22-04-2016 IPR013397 CRISPR-associated protein Csy1 TOLA_RS06945 0fb0d14858697bc84f995d309a688ab0 438 TIGRFAM TIGR02564 cas_Csy1: CRISPR type I-F/YPEST-associated protein Csy1 60 428 1.1E-111 T 22-04-2016 IPR013397 CRISPR-associated protein Csy1 TOLA_RS11225 35fb269f1881cb09c8d425b146310da3 65 Pfam PF14056 Domain of unknown function (DUF4250) 9 61 3.7E-20 T 22-04-2016 IPR025346 Protein of unknown function DUF4250 TOLA_RS08905 22ef84ed354cb85a721d02f96bed8659 183 Pfam PF07007 Protein of unknown function (DUF1311) 24 108 1.9E-8 T 22-04-2016 IPR009739 Protein of unknown function DUF1311 TOLA_RS12295 51b11310c59308be6c088ce7637876fa 304 Pfam PF12101 Protein of unknown function (DUF3577) 131 255 5.1E-49 T 22-04-2016 IPR021960 Protein of unknown function DUF3577 TOLA_RS12295 51b11310c59308be6c088ce7637876fa 304 Pfam PF12101 Protein of unknown function (DUF3577) 6 124 2.7E-31 T 22-04-2016 IPR021960 Protein of unknown function DUF3577 TOLA_RS09930 7024b16f0fb9a4031ed10e7beff53445 213 Pfam PF12261 Thermostable hemolysin 14 184 3.6E-61 T 22-04-2016 IPR022050 Thermostable hemolysin TOLA_RS02135 9d176ade4dff40e5355562bccf836297 111 Pfam PF13453 Transcription factor zinc-finger 2 43 1.3E-21 T 22-04-2016 IPR027392 Transcription factor zinc-finger TOLA_RS07560 7ea81aeb2a936d09b27e9bf54e041849 86 Pfam PF04193 PQ loop repeat 7 61 3.9E-11 T 22-04-2016 IPR006603 PQ-loop repeat TOLA_RS01885 668af7eba68c9bb7c2821842ec6cc94e 257 Pfam PF01203 Type II secretion system (T2SS), protein N 41 249 3.2E-54 T 22-04-2016 IPR022792 Type II secretion system, protein N TOLA_RS02425 456383f7762f0120d2e8f460173412a3 306 Pfam PF03547 Membrane transport protein 14 136 1.8E-10 T 22-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 TOLA_RS06485 82f21c5eed57fac3f2b8dc10e1a4b251 104 Pfam PF11006 Protein of unknown function (DUF2845) 25 100 2.4E-12 T 22-04-2016 IPR021268 Protein of unknown function DUF2845 TOLA_RS09215 dcbaa4bff94baec2030a5c89f3fddc13 92 Pfam PF04221 RelB antitoxin 5 77 5.6E-6 T 22-04-2016 IPR007337 RelB antitoxin/Antitoxin DinJ TOLA_RS16165 bef1009cc152b38998bc9868d565b4d6 103 Pfam PF11604 Copper binding periplasmic protein CusF 33 96 1.5E-16 T 22-04-2016 IPR021647 Copper binding periplasmic protein CusF TOLA_RS04600 424e17bf82d34b198d5a9a5c70ad9a3b 62 Pfam PF12065 Protein of unknown function (DUF3545) 1 59 2.0E-23 T 22-04-2016 IPR021932 Protein of unknown function DUF3545 TOLA_RS16230 5b55798805dc35f7b5f5138792a4f82c 231 Pfam PF11740 Plasmid replication region DNA-binding N-term 7 117 1.2E-19 T 22-04-2016 IPR021104 KfrA, N-terminal DNA-binding domain TOLA_RS11910 f13eefc40e14a290cc0a5ef0ea0afa1e 108 Pfam PF03206 Nitrogen fixation protein NifW 7 103 1.4E-24 T 22-04-2016 IPR004893 Nitrogen fixation protein NifW GO:0009399 TOLA_RS02430 6fc7ebe58675a129d33ef61da6bdcd84 79 Pfam PF11173 Protein of unknown function (DUF2960) 1 79 2.5E-35 T 22-04-2016 IPR021343 Protein of unknown function DUF2960 TOLA_RS08065 88c62c51de3adc0a4032e897d4faf00d 63 Pfam PF03889 Domain of unknown function 15 52 5.1E-22 T 22-04-2016 IPR005589 Protein of unknown function DUF331 TOLA_RS15575 3c81e4b255207a726355b8aca57cf70f 86 Pfam PF05488 PAAR motif 49 79 1.7E-8 T 22-04-2016 IPR008727 PAAR motif TOLA_RS15575 3c81e4b255207a726355b8aca57cf70f 86 Pfam PF05488 PAAR motif 4 51 5.1E-17 T 22-04-2016 IPR008727 PAAR motif TOLA_RS10165 dc648ccae4dd896ff2d5b8c4d2dc7305 298 Pfam PF11154 Protein of unknown function (DUF2934) 28 63 3.5E-13 T 22-04-2016 IPR021327 Protein of unknown function DUF2934