locus-tag class description SPICA_RS00005 PF11638 DnaA N-terminal domain SPICA_RS00005 PF08299 Bacterial dnaA protein helix-turn-helix SPICA_RS00005 PF00308 Bacterial dnaA protein SPICA_RS00010 PF00712 DNA polymerase III beta subunit, N-terminal domain SPICA_RS00010 PF02767 DNA polymerase III beta subunit, central domain SPICA_RS00010 PF02768 DNA polymerase III beta subunit, C-terminal domain SPICA_RS00015 PF02463 RecF/RecN/SMC N terminal domain SPICA_RS00025 PF00468 Ribosomal protein L34 SPICA_RS00030 PF00825 Ribonuclease P SPICA_RS00035 PF14849 YidC periplasmic domain SPICA_RS00035 PF02096 60Kd inner membrane protein SPICA_RS00040 PF14804 Jag N-terminus SPICA_RS00040 PF01424 R3H domain SPICA_RS00050 PF00700 Bacterial flagellin C-terminal helical region SPICA_RS00050 PF00669 Bacterial flagellin N-terminal helical region SPICA_RS00055 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SPICA_RS00075 PF08668 HDOD domain SPICA_RS00080 PF13654 AAA domain SPICA_RS00080 PF05362 Lon protease (S16) C-terminal proteolytic domain SPICA_RS00090 PF00672 HAMP domain SPICA_RS00090 PF02743 Cache domain SPICA_RS00090 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS00100 PF01784 NIF3 (NGG1p interacting factor 3) SPICA_RS00105 PF01252 Signal peptidase (SPase) II SPICA_RS00135 PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SPICA_RS00135 PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SPICA_RS00140 PF03063 Prismane/CO dehydrogenase family SPICA_RS00150 PF09297 NADH pyrophosphatase zinc ribbon domain SPICA_RS00150 PF00293 NUDIX domain SPICA_RS00160 PF02743 Cache domain SPICA_RS00160 PF06580 Histidine kinase SPICA_RS00160 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS00160 PF00672 HAMP domain SPICA_RS00165 PF00072 Response regulator receiver domain SPICA_RS00165 PF04397 LytTr DNA-binding domain SPICA_RS00170 PF13407 Periplasmic binding protein domain SPICA_RS00175 PF13407 Periplasmic binding protein domain SPICA_RS00180 PF00005 ABC transporter SPICA_RS00185 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS00190 PF01554 MatE SPICA_RS00200 PF04225 Opacity-associated protein A LysM-like domain SPICA_RS00200 PF01551 Peptidase family M23 SPICA_RS00210 PF03885 Protein of unknown function (DUF327) SPICA_RS00215 PF04468 PSP1 C-terminal conserved region SPICA_RS00225 PF02449 Beta-galactosidase SPICA_RS00225 PF08532 Beta-galactosidase trimerisation domain SPICA_RS00225 PF08533 Beta-galactosidase C-terminal domain SPICA_RS00230 PF02511 Thymidylate synthase complementing protein SPICA_RS00240 PF00672 HAMP domain SPICA_RS00240 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS00245 PF02782 FGGY family of carbohydrate kinases, C-terminal domain SPICA_RS00245 PF00370 FGGY family of carbohydrate kinases, N-terminal domain SPICA_RS00250 PF13472 GDSL-like Lipase/Acylhydrolase family SPICA_RS00270 PF00544 Pectate lyase SPICA_RS00275 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS00290 PF00293 NUDIX domain SPICA_RS00300 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS00305 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS00310 PF00072 Response regulator receiver domain SPICA_RS00315 PF13361 UvrD-like helicase C-terminal domain SPICA_RS00315 PF00580 UvrD/REP helicase N-terminal domain SPICA_RS00315 PF12705 PD-(D/E)XK nuclease superfamily SPICA_RS00325 PF16257 tagaturonate epimerase SPICA_RS00330 PF00106 short chain dehydrogenase SPICA_RS00335 PF08220 DeoR-like helix-turn-helix domain SPICA_RS00335 PF00455 DeoR C terminal sensor domain SPICA_RS00345 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPICA_RS00345 PF03714 Bacterial pullanase-associated domain SPICA_RS00345 PF00128 Alpha amylase, catalytic domain SPICA_RS00365 PF00465 Iron-containing alcohol dehydrogenase SPICA_RS00370 PF00672 HAMP domain SPICA_RS00370 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS00370 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS00370 PF13755 Sensor N-terminal transmembrane domain SPICA_RS00370 PF13756 Stimulus-sensing domain SPICA_RS00410 PF00072 Response regulator receiver domain SPICA_RS00410 PF00486 Transcriptional regulatory protein, C terminal SPICA_RS00420 PF17999 Pullulanase N1-terminal domain SPICA_RS00420 PF00128 Alpha amylase, catalytic domain SPICA_RS00420 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPICA_RS00425 PF11941 Domain of unknown function (DUF3459) SPICA_RS00425 PF00128 Alpha amylase, catalytic domain SPICA_RS00435 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS00440 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS00450 PF02903 Alpha amylase, N-terminal ig-like domain SPICA_RS00450 PF16657 Maltogenic Amylase, C-terminal domain SPICA_RS00450 PF00128 Alpha amylase, catalytic domain SPICA_RS00505 PF18273 Type III R-M EcoP15I C-terminal domain SPICA_RS00505 PF01555 DNA methylase SPICA_RS00530 PF01850 PIN domain SPICA_RS00535 PF04014 Antidote-toxin recognition MazE, bacterial antitoxin SPICA_RS00575 PF00464 Serine hydroxymethyltransferase SPICA_RS00580 PF03928 Haem-degrading SPICA_RS00595 PF07730 Histidine kinase SPICA_RS00600 PF00072 Response regulator receiver domain SPICA_RS00600 PF00196 Bacterial regulatory proteins, luxR family SPICA_RS00610 PF13407 Periplasmic binding protein domain SPICA_RS00615 PF13407 Periplasmic binding protein domain SPICA_RS00620 PF00005 ABC transporter SPICA_RS00625 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS00630 PF08125 Mannitol dehydrogenase C-terminal domain SPICA_RS00630 PF01232 Mannitol dehydrogenase Rossmann domain SPICA_RS00655 PF00175 Oxidoreductase NAD-binding domain SPICA_RS00655 PF00970 Oxidoreductase FAD-binding domain SPICA_RS00655 PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B SPICA_RS00660 PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster SPICA_RS00660 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPICA_RS00660 PF13247 4Fe-4S dicluster domain SPICA_RS00665 PF00027 Cyclic nucleotide-binding domain SPICA_RS00665 PF07885 Ion channel SPICA_RS00670 PF02872 5'-nucleotidase, C-terminal domain SPICA_RS00670 PF00149 Calcineurin-like phosphoesterase SPICA_RS00695 PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase SPICA_RS00720 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS00725 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS00730 PF01547 Bacterial extracellular solute-binding protein SPICA_RS00735 PF00196 Bacterial regulatory proteins, luxR family SPICA_RS00735 PF00072 Response regulator receiver domain SPICA_RS00740 PF07730 Histidine kinase SPICA_RS00745 PF01458 Uncharacterized protein family (UPF0051) SPICA_RS00750 PF00005 ABC transporter SPICA_RS00765 PF17759 Phenylalanyl tRNA synthetase beta chain CLM domain SPICA_RS00765 PF03484 tRNA synthetase B5 domain SPICA_RS00770 PF01409 tRNA synthetases class II core domain (F) SPICA_RS00785 PF01694 Rhomboid family SPICA_RS00785 PF12122 Cytoplasmic N-terminal domain of rhomboid serine protease SPICA_RS00795 PF00990 Diguanylate cyclase, GGDEF domain SPICA_RS00795 PF07694 5TMR of 5TMR-LYT SPICA_RS00800 PF01207 Dihydrouridine synthase (Dus) SPICA_RS00805 PF01026 TatD related DNase SPICA_RS00815 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPICA_RS00815 PF01872 RibD C-terminal domain SPICA_RS00820 PF00677 Lumazine binding domain SPICA_RS00825 PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase SPICA_RS00825 PF00925 GTP cyclohydrolase II SPICA_RS00830 PF00885 6,7-dimethyl-8-ribityllumazine synthase SPICA_RS00835 PF08543 Phosphomethylpyrimidine kinase SPICA_RS00840 PF02110 Hydroxyethylthiazole kinase family SPICA_RS00845 PF02581 Thiamine monophosphate synthase SPICA_RS00850 PF13419 Haloacid dehalogenase-like hydrolase SPICA_RS00855 PF00425 chorismate binding enzyme SPICA_RS00855 PF04715 Anthranilate synthase component I, N terminal region SPICA_RS00860 PF00117 Glutamine amidotransferase class-I SPICA_RS00860 PF02885 Glycosyl transferase family, helical bundle domain SPICA_RS00860 PF00591 Glycosyl transferase family, a/b domain SPICA_RS00870 PF00291 Pyridoxal-phosphate dependent enzyme SPICA_RS00875 PF00290 Tryptophan synthase alpha chain SPICA_RS00880 PF11842 Domain of unknown function (DUF3362) SPICA_RS00880 PF04055 Radical SAM superfamily SPICA_RS00880 PF08497 Radical SAM N-terminal SPICA_RS00885 PF01106 NifU-like domain SPICA_RS00890 PF04102 SlyX SPICA_RS00895 PF00365 Phosphofructokinase SPICA_RS00910 PF01627 Hpt domain SPICA_RS00910 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS00910 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS00910 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPICA_RS00910 PF00072 Response regulator receiver domain SPICA_RS00915 PF00588 SpoU rRNA Methylase family SPICA_RS00915 PF08032 RNA 2'-O ribose methyltransferase substrate binding SPICA_RS00920 PF02272 DHHA1 domain SPICA_RS00920 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SPICA_RS00920 PF01411 tRNA synthetases class II (A) SPICA_RS00925 PF01923 Cobalamin adenosyltransferase SPICA_RS00945 PF00873 AcrB/AcrD/AcrF family SPICA_RS00955 PF00459 Inositol monophosphatase family SPICA_RS00960 PF02424 ApbE family SPICA_RS00970 PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPICA_RS00975 PF09984 Uncharacterised signal transduction histidine kinase domain (DUF2222) SPICA_RS00975 PF00672 HAMP domain SPICA_RS00975 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS00975 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS00975 PF01627 Hpt domain SPICA_RS00975 PF00072 Response regulator receiver domain SPICA_RS00980 PF00370 FGGY family of carbohydrate kinases, N-terminal domain SPICA_RS00980 PF02782 FGGY family of carbohydrate kinases, C-terminal domain SPICA_RS00990 PF02132 RecR protein SPICA_RS00990 PF13662 Toprim domain SPICA_RS00995 PF02575 YbaB/EbfC DNA-binding family SPICA_RS01000 PF12170 DNA polymerase III tau subunit V interacting with alpha SPICA_RS01000 PF12168 DNA polymerase III subunits tau domain IV DnaB-binding SPICA_RS01000 PF12169 DNA polymerase III subunits gamma and tau domain III SPICA_RS01055 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS01060 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS01070 PF00072 Response regulator receiver domain SPICA_RS01070 PF00196 Bacterial regulatory proteins, luxR family SPICA_RS01075 PF07730 Histidine kinase SPICA_RS01110 PF02906 Iron only hydrogenase large subunit, C-terminal domain SPICA_RS01110 PF12838 4Fe-4S dicluster domain SPICA_RS01110 PF02256 Iron hydrogenase small subunit SPICA_RS01115 PF02810 SEC-C motif SPICA_RS01120 PF00892 EamA-like transporter family SPICA_RS01130 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPICA_RS01150 PF00072 Response regulator receiver domain SPICA_RS01150 PF00486 Transcriptional regulatory protein, C terminal SPICA_RS01155 PF04012 PspA/IM30 family SPICA_RS01175 PF00588 SpoU rRNA Methylase family SPICA_RS01185 PF00072 Response regulator receiver domain SPICA_RS01185 PF02954 Bacterial regulatory protein, Fis family SPICA_RS01185 PF00158 Sigma-54 interaction domain SPICA_RS01195 PF04452 RNA methyltransferase SPICA_RS01200 PF03572 Peptidase family S41 SPICA_RS01200 PF17820 PDZ domain SPICA_RS01200 PF01471 Putative peptidoglycan binding domain SPICA_RS01210 PF10609 NUBPL iron-transfer P-loop NTPase SPICA_RS01220 PF01790 Prolipoprotein diacylglyceryl transferase SPICA_RS01225 PF14821 Threonine synthase N terminus SPICA_RS01225 PF00291 Pyridoxal-phosphate dependent enzyme SPICA_RS01230 PF00011 Hsp20/alpha crystallin family SPICA_RS01240 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPICA_RS01240 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPICA_RS01240 PF02378 Phosphotransferase system, EIIC SPICA_RS01245 PF02779 Transketolase, pyrimidine binding domain SPICA_RS01245 PF00456 Transketolase, thiamine diphosphate binding domain SPICA_RS01255 PF02595 Glycerate kinase family SPICA_RS01260 PF17853 GGDEF-like domain SPICA_RS01260 PF05651 Putative sugar diacid recognition SPICA_RS01260 PF13556 PucR C-terminal helix-turn-helix domain SPICA_RS01265 PF00691 OmpA family SPICA_RS01265 PF05736 OprF membrane domain SPICA_RS01270 PF17284 Spermidine synthase tetramerisation domain SPICA_RS01275 PF02675 S-adenosylmethionine decarboxylase SPICA_RS01290 PF07690 Major Facilitator Superfamily SPICA_RS01350 PF01336 OB-fold nucleic acid binding domain SPICA_RS01350 PF02938 GAD domain SPICA_RS01350 PF00152 tRNA synthetases class II (D, K and N) SPICA_RS01355 PF02308 MgtC family SPICA_RS01360 PF03692 Putative zinc- or iron-chelating domain SPICA_RS01375 PF00370 FGGY family of carbohydrate kinases, N-terminal domain SPICA_RS01375 PF02782 FGGY family of carbohydrate kinases, C-terminal domain SPICA_RS01380 PF13793 N-terminal domain of ribose phosphate pyrophosphokinase SPICA_RS01380 PF14572 Phosphoribosyl synthetase-associated domain SPICA_RS01385 PF00691 OmpA family SPICA_RS01400 PF04014 Antidote-toxin recognition MazE, bacterial antitoxin SPICA_RS01405 PF01850 PIN domain SPICA_RS01445 PF13635 Domain of unknown function (DUF4143) SPICA_RS01445 PF13173 AAA domain SPICA_RS01450 PF11230 Protein of unknown function (DUF3029) SPICA_RS01455 PF04055 Radical SAM superfamily SPICA_RS01475 PF06165 Glycosyltransferase family 36 SPICA_RS01475 PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain SPICA_RS01490 PF00501 AMP-binding enzyme SPICA_RS01495 PF00072 Response regulator receiver domain SPICA_RS01500 PF17149 Periplasmic sensor domain found in signal transduction proteins SPICA_RS01500 PF00672 HAMP domain SPICA_RS01500 PF01627 Hpt domain SPICA_RS01500 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS01500 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS01500 PF00072 Response regulator receiver domain SPICA_RS01510 PF00183 Hsp90 protein SPICA_RS01515 PF16874 Glycosyl hydrolase family 36 C-terminal domain SPICA_RS01515 PF16875 Glycosyl hydrolase family 36 N-terminal domain SPICA_RS01525 PF00005 ABC transporter SPICA_RS01525 PF00664 ABC transporter transmembrane region SPICA_RS01530 PF00005 ABC transporter SPICA_RS01530 PF00664 ABC transporter transmembrane region SPICA_RS01540 PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain SPICA_RS01540 PF02777 Iron/manganese superoxide dismutases, C-terminal domain SPICA_RS01555 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS01560 PF00196 Bacterial regulatory proteins, luxR family SPICA_RS01560 PF00072 Response regulator receiver domain SPICA_RS01565 PF03512 Glycosyl hydrolase family 52 SPICA_RS01570 PF01547 Bacterial extracellular solute-binding protein SPICA_RS01575 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS01580 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS01585 PF16868 NMT1-like family SPICA_RS01610 PF00211 Adenylate and Guanylate cyclase catalytic domain SPICA_RS01620 PF00266 Aminotransferase class-V SPICA_RS01630 PF01458 Uncharacterized protein family (UPF0051) SPICA_RS01635 PF00005 ABC transporter SPICA_RS01645 PF02525 Flavodoxin-like fold SPICA_RS01650 PF04452 RNA methyltransferase SPICA_RS01670 PF11897 Protein of unknown function (DUF3417) SPICA_RS01670 PF00343 Carbohydrate phosphorylase SPICA_RS01680 PF08281 Sigma-70, region 4 SPICA_RS01680 PF04542 Sigma-70 region 2 SPICA_RS01700 PF01266 FAD dependent oxidoreductase SPICA_RS01700 PF04324 BFD-like [2Fe-2S] binding domain SPICA_RS01715 PF13167 GTP-binding GTPase N-terminal SPICA_RS01715 PF01926 50S ribosome-binding GTPase SPICA_RS01715 PF16360 GTP-binding GTPase Middle Region SPICA_RS01720 PF01551 Peptidase family M23 SPICA_RS01720 PF10145 Phage-related minor tail protein SPICA_RS01720 PF01464 Transglycosylase SLT domain SPICA_RS01745 PF02577 Bifunctional nuclease SPICA_RS01750 PF00348 Polyprenyl synthetase SPICA_RS01755 PF01728 FtsJ-like methyltransferase SPICA_RS01775 PF00480 ROK family SPICA_RS01780 PF01547 Bacterial extracellular solute-binding protein SPICA_RS01785 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS01790 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS01795 PF17167 Glycosyl hydrolase 36 superfamily, catalytic domain SPICA_RS01795 PF06165 Glycosyltransferase family 36 SPICA_RS01810 PF07670 Nucleoside recognition SPICA_RS01810 PF02421 Ferrous iron transport protein B SPICA_RS01810 PF17910 FeoB cytosolic helical domain SPICA_RS01810 PF07664 Ferrous iron transport protein B C terminus SPICA_RS01810 PF04023 FeoA domain SPICA_RS01815 PF00106 short chain dehydrogenase SPICA_RS01820 PF09397 Ftsk gamma domain SPICA_RS01820 PF17854 FtsK alpha domain SPICA_RS01820 PF01580 FtsK/SpoIIIE family SPICA_RS01840 PF02646 RmuC family SPICA_RS01845 PF01972 Serine dehydrogenase proteinase SPICA_RS01845 PF01957 NfeD-like C-terminal, partner-binding SPICA_RS01850 PF12127 SigmaW regulon antibacterial SPICA_RS01870 PF01048 Phosphorylase superfamily SPICA_RS01885 PF00471 Ribosomal protein L33 SPICA_RS01895 PF00584 SecE/Sec61-gamma subunits of protein translocation complex SPICA_RS01900 PF02357 Transcription termination factor nusG SPICA_RS01900 PF00467 KOW motif SPICA_RS01905 PF00298 Ribosomal protein L11, RNA binding domain SPICA_RS01905 PF03946 Ribosomal protein L11, N-terminal domain SPICA_RS01910 PF00687 Ribosomal protein L1p/L10e family SPICA_RS01915 PF00466 Ribosomal protein L10 SPICA_RS01920 PF00542 Ribosomal protein L7/L12 C-terminal domain SPICA_RS01920 PF16320 Ribosomal protein L7/L12 dimerisation domain SPICA_RS01925 PF04565 RNA polymerase Rpb2, domain 3 SPICA_RS01925 PF10385 RNA polymerase beta subunit external 1 domain SPICA_RS01925 PF00562 RNA polymerase Rpb2, domain 6 SPICA_RS01925 PF04560 RNA polymerase Rpb2, domain 7 SPICA_RS01925 PF04561 RNA polymerase Rpb2, domain 2 SPICA_RS01925 PF04563 RNA polymerase beta subunit SPICA_RS01930 PF04983 RNA polymerase Rpb1, domain 3 SPICA_RS01930 PF04998 RNA polymerase Rpb1, domain 5 SPICA_RS01930 PF04997 RNA polymerase Rpb1, domain 1 SPICA_RS01930 PF05000 RNA polymerase Rpb1, domain 4 SPICA_RS01930 PF00623 RNA polymerase Rpb1, domain 2 SPICA_RS01935 PF00164 Ribosomal protein S12/S23 SPICA_RS01940 PF00177 Ribosomal protein S7p/S5e SPICA_RS01945 PF03143 Elongation factor Tu C-terminal domain SPICA_RS01945 PF03144 Elongation factor Tu domain 2 SPICA_RS01945 PF00009 Elongation factor Tu GTP binding domain SPICA_RS01950 PF00338 Ribosomal protein S10p/S20e SPICA_RS01955 PF00297 Ribosomal protein L3 SPICA_RS01960 PF00573 Ribosomal protein L4/L1 family SPICA_RS01965 PF00276 Ribosomal protein L23 SPICA_RS01970 PF00181 Ribosomal Proteins L2, RNA binding domain SPICA_RS01970 PF03947 Ribosomal Proteins L2, C-terminal domain SPICA_RS01975 PF00203 Ribosomal protein S19 SPICA_RS01980 PF00237 Ribosomal protein L22p/L17e SPICA_RS01985 PF07650 KH domain SPICA_RS01985 PF00189 Ribosomal protein S3, C-terminal domain SPICA_RS01990 PF00252 Ribosomal protein L16p/L10e SPICA_RS01995 PF00831 Ribosomal L29 protein SPICA_RS02000 PF00366 Ribosomal protein S17 SPICA_RS02005 PF00238 Ribosomal protein L14p/L23e SPICA_RS02010 PF00467 KOW motif SPICA_RS02010 PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 SPICA_RS02015 PF00673 ribosomal L5P family C-terminus SPICA_RS02015 PF00281 Ribosomal protein L5 SPICA_RS02020 PF00410 Ribosomal protein S8 SPICA_RS02025 PF00347 Ribosomal protein L6 SPICA_RS02030 PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast SPICA_RS02035 PF03719 Ribosomal protein S5, C-terminal domain SPICA_RS02035 PF00333 Ribosomal protein S5, N-terminal domain SPICA_RS02040 PF00327 Ribosomal protein L30p/L7e SPICA_RS02045 PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SPICA_RS02050 PF00344 SecY translocase SPICA_RS02055 PF00416 Ribosomal protein S13/S18 SPICA_RS02060 PF00411 Ribosomal protein S11 SPICA_RS02065 PF01479 S4 domain SPICA_RS02065 PF00163 Ribosomal protein S4/S9 N-terminal domain SPICA_RS02070 PF01000 RNA polymerase Rpb3/RpoA insert domain SPICA_RS02070 PF03118 Bacterial RNA polymerase, alpha chain C terminal domain SPICA_RS02070 PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain SPICA_RS02075 PF01196 Ribosomal protein L17 SPICA_RS02080 PF13458 Periplasmic binding protein SPICA_RS02085 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS02090 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS02090 PF11862 Domain of unknown function (DUF3382) SPICA_RS02095 PF00005 ABC transporter SPICA_RS02095 PF12399 Branched-chain amino acid ATP-binding cassette transporter SPICA_RS02100 PF00005 ABC transporter SPICA_RS02105 PF00571 CBS domain SPICA_RS02105 PF00478 IMP dehydrogenase / GMP reductase domain SPICA_RS02110 PF04607 Region found in RelA / SpoT proteins SPICA_RS02110 PF02824 TGS domain SPICA_RS02115 PF17827 PrmC N-terminal domain SPICA_RS02115 PF05175 Methyltransferase small domain SPICA_RS02120 PF03462 PCRF domain SPICA_RS02120 PF00472 RF-1 domain SPICA_RS02125 PF13181 Tetratricopeptide repeat SPICA_RS02125 PF05420 Cellulose synthase operon protein C C-terminus (BCSC_C) SPICA_RS02130 PF00962 Adenosine/AMP deaminase SPICA_RS02150 PF00118 TCP-1/cpn60 chaperonin family SPICA_RS02155 PF01842 ACT domain SPICA_RS02155 PF03315 Serine dehydratase beta chain SPICA_RS02160 PF03313 Serine dehydratase alpha chain SPICA_RS02165 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SPICA_RS02165 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SPICA_RS02170 PF00793 DAHP synthetase I family SPICA_RS02175 PF00075 RNase H SPICA_RS02180 PF02229 Transcriptional Coactivator p15 (PC4) SPICA_RS02210 PF02074 Carboxypeptidase Taq (M32) metallopeptidase SPICA_RS02225 PF01066 CDP-alcohol phosphatidyltransferase SPICA_RS02280 PF02446 4-alpha-glucanotransferase SPICA_RS02290 PF03144 Elongation factor Tu domain 2 SPICA_RS02290 PF03764 Elongation factor G, domain IV SPICA_RS02290 PF00009 Elongation factor Tu GTP binding domain SPICA_RS02290 PF14492 Elongation Factor G, domain II SPICA_RS02290 PF00679 Elongation factor G C-terminus SPICA_RS02305 PF01121 Dephospho-CoA kinase SPICA_RS02310 PF01367 5'-3' exonuclease, C-terminal SAM fold SPICA_RS02310 PF01612 3'-5' exonuclease SPICA_RS02310 PF00476 DNA polymerase family A SPICA_RS02310 PF02739 5'-3' exonuclease, N-terminal resolvase-like domain SPICA_RS02320 PF02561 Flagellar protein FliS SPICA_RS02325 PF08544 GHMP kinases C terminal SPICA_RS02325 PF10509 Galactokinase galactose-binding signature SPICA_RS02325 PF00288 GHMP kinases N terminal domain SPICA_RS02330 PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain SPICA_RS02330 PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain SPICA_RS02340 PF05552 Conserved TM helix SPICA_RS02340 PF00924 Mechanosensitive ion channel SPICA_RS02345 PF17862 AAA+ lid domain SPICA_RS02345 PF00004 ATPase family associated with various cellular activities (AAA) SPICA_RS02345 PF01434 Peptidase family M41 SPICA_RS02355 PF01985 CRS1 / YhbY (CRM) domain SPICA_RS02370 PF00919 Uncharacterized protein family UPF0004 SPICA_RS02370 PF18693 TRAM domain SPICA_RS02370 PF04055 Radical SAM superfamily SPICA_RS02375 PF00580 UvrD/REP helicase N-terminal domain SPICA_RS02375 PF13361 UvrD-like helicase C-terminal domain SPICA_RS02395 PF00572 Ribosomal protein L13 SPICA_RS02400 PF00380 Ribosomal protein S9/S16 SPICA_RS02405 PF02631 RecX family SPICA_RS02410 PF00072 Response regulator receiver domain SPICA_RS02415 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS02415 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS02415 PF08448 PAS fold SPICA_RS02415 PF13188 PAS domain SPICA_RS02415 PF00072 Response regulator receiver domain SPICA_RS02420 PF00708 Acylphosphatase SPICA_RS02430 PF02664 S-Ribosylhomocysteinase (LuxS) SPICA_RS02435 PF01048 Phosphorylase superfamily SPICA_RS02455 PF01590 GAF domain SPICA_RS02455 PF00990 Diguanylate cyclase, GGDEF domain SPICA_RS02455 PF00563 EAL domain SPICA_RS02455 PF00360 Phytochrome region SPICA_RS02470 PF02021 Uncharacterised protein family UPF0102 SPICA_RS02475 PF11871 Domain of unknown function (DUF3391) SPICA_RS02475 PF01966 HD domain SPICA_RS02490 PF01245 Ribosomal protein L19 SPICA_RS02495 PF01746 tRNA (Guanine-1)-methyltransferase SPICA_RS02500 PF01782 RimM N-terminal domain SPICA_RS02500 PF05239 PRC-barrel domain SPICA_RS02510 PF00886 Ribosomal protein S16 SPICA_RS02515 PF02881 SRP54-type protein, helical bundle domain SPICA_RS02515 PF00448 SRP54-type protein, GTPase domain SPICA_RS02515 PF02978 Signal peptide binding domain SPICA_RS02520 PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SPICA_RS02520 PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SPICA_RS02530 PF00334 Nucleoside diphosphate kinase SPICA_RS02535 PF01416 tRNA pseudouridine synthase SPICA_RS02540 PF00579 tRNA synthetases class I (W and Y) SPICA_RS02550 PF12683 Protein of unknown function (DUF3798) SPICA_RS02555 PF00072 Response regulator receiver domain SPICA_RS02560 PF00271 Helicase conserved C-terminal domain SPICA_RS02560 PF00176 SNF2 family N-terminal domain SPICA_RS02585 PF16363 GDP-mannose 4,6 dehydratase SPICA_RS02590 PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family SPICA_RS02600 PF03102 NeuB family SPICA_RS02600 PF08666 SAF domain SPICA_RS02605 PF02350 UDP-N-acetylglucosamine 2-epimerase SPICA_RS02610 PF00483 Nucleotidyl transferase SPICA_RS02620 PF02348 Cytidylyltransferase SPICA_RS02650 PF00795 Carbon-nitrogen hydrolase SPICA_RS02650 PF02540 NAD synthase SPICA_RS02655 PF00117 Glutamine amidotransferase class-I SPICA_RS02660 PF00977 Histidine biosynthesis protein SPICA_RS02665 PF08485 Polysaccharide biosynthesis protein C-terminal SPICA_RS02665 PF02719 Polysaccharide biosynthesis protein SPICA_RS02670 PF01370 NAD dependent epimerase/dehydratase family SPICA_RS02675 PF02350 UDP-N-acetylglucosamine 2-epimerase SPICA_RS02685 PF00483 Nucleotidyl transferase SPICA_RS02690 PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase SPICA_RS02695 PF04321 RmlD substrate binding domain SPICA_RS02720 PF16363 GDP-mannose 4,6 dehydratase SPICA_RS02740 PF00005 ABC transporter SPICA_RS02760 PF02690 Na+/Pi-cotransporter SPICA_RS02765 PF00753 Metallo-beta-lactamase superfamily SPICA_RS02775 PF03880 DbpA RNA binding domain SPICA_RS02785 PF03952 Enolase, N-terminal domain SPICA_RS02785 PF00113 Enolase, C-terminal TIM barrel domain SPICA_RS02805 PF01040 UbiA prenyltransferase family SPICA_RS02810 PF12282 Signal transduction histidine kinase SPICA_RS02810 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS02810 PF07568 Histidine kinase SPICA_RS02820 PF01734 Patatin-like phospholipase SPICA_RS02825 PF00132 Bacterial transferase hexapeptide (six repeats) SPICA_RS02835 PF01926 50S ribosome-binding GTPase SPICA_RS02835 PF07650 KH domain SPICA_RS02845 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPICA_RS02845 PF02403 Seryl-tRNA synthetase N-terminal domain SPICA_RS02850 PF03099 Biotin/lipoate A/B protein ligase family SPICA_RS02850 PF08279 HTH domain SPICA_RS02850 PF02237 Biotin protein ligase C terminal domain SPICA_RS02865 PF02463 RecF/RecN/SMC N terminal domain SPICA_RS02865 PF06470 SMC proteins Flexible Hinge Domain SPICA_RS02885 PF01850 PIN domain SPICA_RS02895 PF12848 ABC transporter SPICA_RS02895 PF00005 ABC transporter SPICA_RS02900 PF00271 Helicase conserved C-terminal domain SPICA_RS02900 PF00270 DEAD/DEAH box helicase SPICA_RS02925 PF00011 Hsp20/alpha crystallin family SPICA_RS02930 PF04055 Radical SAM superfamily SPICA_RS02930 PF06969 HemN C-terminal domain SPICA_RS02935 PF00654 Voltage gated chloride channel SPICA_RS02940 PF00375 Sodium:dicarboxylate symporter family SPICA_RS02950 PF00440 Bacterial regulatory proteins, tetR family SPICA_RS02955 PF02926 THUMP domain SPICA_RS02955 PF01170 Putative RNA methylase family UPF0020 SPICA_RS02960 PF18125 RlmM ferredoxin-like domain SPICA_RS02960 PF01728 FtsJ-like methyltransferase SPICA_RS02980 PF01032 FecCD transport family SPICA_RS03020 PF01522 Polysaccharide deacetylase SPICA_RS03020 PF00457 Glycosyl hydrolases family 11 SPICA_RS03020 PF03422 Carbohydrate binding module (family 6) SPICA_RS03025 PF01270 Glycosyl hydrolases family 8 SPICA_RS03030 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS03035 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS03045 PF03786 D-mannonate dehydratase (UxuA) SPICA_RS03050 PF03648 Glycosyl hydrolase family 67 N-terminus SPICA_RS03050 PF07488 Glycosyl hydrolase family 67 middle domain SPICA_RS03050 PF07477 Glycosyl hydrolase family 67 C-terminus SPICA_RS03055 PF14310 Fibronectin type III-like domain SPICA_RS03055 PF01915 Glycosyl hydrolase family 3 C-terminal domain SPICA_RS03055 PF07691 PA14 domain SPICA_RS03055 PF00933 Glycosyl hydrolase family 3 N terminal domain SPICA_RS03060 PF02056 Family 4 glycosyl hydrolase SPICA_RS03060 PF11975 Family 4 glycosyl hydrolase C-terminal domain SPICA_RS03065 PF11975 Family 4 glycosyl hydrolase C-terminal domain SPICA_RS03065 PF02056 Family 4 glycosyl hydrolase SPICA_RS03070 PF00106 short chain dehydrogenase SPICA_RS03075 PF00392 Bacterial regulatory proteins, gntR family SPICA_RS03075 PF07729 FCD domain SPICA_RS03085 PF00549 CoA-ligase SPICA_RS03085 PF02629 CoA binding domain SPICA_RS03090 PF06545 Protein of unknown function (DUF1116) SPICA_RS03105 PF07729 FCD domain SPICA_RS03105 PF00392 Bacterial regulatory proteins, gntR family SPICA_RS03110 PF03450 CO dehydrogenase flavoprotein C-terminal domain SPICA_RS03110 PF00941 FAD binding domain in molybdopterin dehydrogenase SPICA_RS03120 PF00860 Permease family SPICA_RS03140 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS03145 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS03150 PF17137 Domain of unknown function (DUF5110) SPICA_RS03150 PF16338 Domain of unknown function (DUF4968) SPICA_RS03150 PF01055 Glycosyl hydrolases family 31 SPICA_RS03150 PF13802 Galactose mutarotase-like SPICA_RS03155 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS03160 PF01081 KDPG and KHG aldolase SPICA_RS03170 PF04962 KduI/IolB family SPICA_RS03180 PF01614 Bacterial transcriptional regulator SPICA_RS03180 PF09339 IclR helix-turn-helix domain SPICA_RS03185 PF02614 Glucuronate isomerase SPICA_RS03190 PF01758 Sodium Bile acid symporter family SPICA_RS03195 PF12833 Helix-turn-helix domain SPICA_RS03195 PF02311 AraC-like ligand binding domain SPICA_RS03200 PF07470 Glycosyl Hydrolase Family 88 SPICA_RS03210 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS03215 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS03220 PF13416 Bacterial extracellular solute-binding protein SPICA_RS03230 PF13229 Right handed beta helix region SPICA_RS03255 PF01758 Sodium Bile acid symporter family SPICA_RS03265 PF13187 4Fe-4S dicluster domain SPICA_RS03265 PF04060 Putative Fe-S cluster SPICA_RS03265 PF00037 4Fe-4S binding domain SPICA_RS03270 PF02508 Rnf-Nqr subunit, membrane protein SPICA_RS03275 PF02508 Rnf-Nqr subunit, membrane protein SPICA_RS03280 PF04205 FMN-binding domain SPICA_RS03285 PF03116 NQR2, RnfD, RnfE family SPICA_RS03290 PF10531 SLBB domain SPICA_RS03290 PF13375 RnfC Barrel sandwich hybrid domain SPICA_RS03290 PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit SPICA_RS03290 PF13237 4Fe-4S dicluster domain SPICA_RS03300 PF03591 AzlC protein SPICA_RS03305 PF05437 Branched-chain amino acid transport protein (AzlD) SPICA_RS03310 PF02743 Cache domain SPICA_RS03310 PF00672 HAMP domain SPICA_RS03310 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS03315 PF00578 AhpC/TSA family SPICA_RS03320 PF00749 tRNA synthetases class I (E and Q), catalytic domain SPICA_RS03320 PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain SPICA_RS03325 PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SPICA_RS03325 PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain SPICA_RS03330 PF00365 Phosphofructokinase SPICA_RS03345 PF00696 Amino acid kinase family SPICA_RS03350 PF01841 Transglutaminase-like superfamily SPICA_RS03365 PF04542 Sigma-70 region 2 SPICA_RS03365 PF04539 Sigma-70 region 3 SPICA_RS03365 PF04545 Sigma-70, region 4 SPICA_RS03370 PF09190 DALR domain SPICA_RS03370 PF01406 tRNA synthetases class I (C) catalytic domain SPICA_RS03375 PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain SPICA_RS03375 PF01565 FAD binding domain SPICA_RS03385 PF13545 Crp-like helix-turn-helix domain SPICA_RS03385 PF00027 Cyclic nucleotide-binding domain SPICA_RS03405 PF07238 PilZ domain SPICA_RS03420 PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SPICA_RS03425 PF04002 RadC-like JAB domain SPICA_RS03430 PF00210 Ferritin-like domain SPICA_RS03440 PF00155 Aminotransferase class I and II SPICA_RS03450 PF17820 PDZ domain SPICA_RS03450 PF13180 PDZ domain SPICA_RS03490 PF00005 ABC transporter SPICA_RS03500 PF13426 PAS domain SPICA_RS03500 PF00072 Response regulator receiver domain SPICA_RS03500 PF08448 PAS fold SPICA_RS03500 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS03500 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS03510 PF00158 Sigma-54 interaction domain SPICA_RS03510 PF00072 Response regulator receiver domain SPICA_RS03510 PF02954 Bacterial regulatory protein, Fis family SPICA_RS03515 PF00005 ABC transporter SPICA_RS03515 PF02361 Cobalt transport protein SPICA_RS03525 PF03309 Type III pantothenate kinase SPICA_RS03535 PF13419 Haloacid dehalogenase-like hydrolase SPICA_RS03540 PF00210 Ferritin-like domain SPICA_RS03560 PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain SPICA_RS03565 PF02954 Bacterial regulatory protein, Fis family SPICA_RS03565 PF00072 Response regulator receiver domain SPICA_RS03565 PF00158 Sigma-54 interaction domain SPICA_RS03570 PF10417 C-terminal domain of 1-Cys peroxiredoxin SPICA_RS03570 PF00578 AhpC/TSA family SPICA_RS03575 PF00158 Sigma-54 interaction domain SPICA_RS03575 PF01590 GAF domain SPICA_RS03580 PF00871 Acetokinase family SPICA_RS03590 PF01850 PIN domain SPICA_RS03595 PF01547 Bacterial extracellular solute-binding protein SPICA_RS03600 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS03605 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS03610 PF06964 Alpha-L-arabinofuranosidase C-terminal domain SPICA_RS03630 PF13333 Integrase core domain SPICA_RS03630 PF13276 HTH-like domain SPICA_RS03630 PF00665 Integrase core domain SPICA_RS03635 PF01894 Uncharacterised protein family UPF0047 SPICA_RS03640 PF03358 NADPH-dependent FMN reductase SPICA_RS03645 PF01432 Peptidase family M3 SPICA_RS03645 PF08439 Oligopeptidase F SPICA_RS03650 PF00245 Alkaline phosphatase SPICA_RS03660 PF13416 Bacterial extracellular solute-binding protein SPICA_RS03665 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS03670 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS03675 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS03685 PF00873 AcrB/AcrD/AcrF family SPICA_RS03700 PF00486 Transcriptional regulatory protein, C terminal SPICA_RS03700 PF00072 Response regulator receiver domain SPICA_RS03705 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS03705 PF16736 Single Cache-like SPICA_RS03705 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS03705 PF00989 PAS fold SPICA_RS03710 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS03720 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS03725 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS03730 PF01055 Glycosyl hydrolases family 31 SPICA_RS03730 PF13802 Galactose mutarotase-like SPICA_RS03740 PF00248 Aldo/keto reductase family SPICA_RS03750 PF08448 PAS fold SPICA_RS03750 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS03750 PF13426 PAS domain SPICA_RS03750 PF00072 Response regulator receiver domain SPICA_RS03750 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS03775 PF08239 Bacterial SH3 domain SPICA_RS03780 PF00005 ABC transporter SPICA_RS03780 PF16326 ABC transporter C-terminal domain SPICA_RS03780 PF12848 ABC transporter SPICA_RS03785 PF16363 GDP-mannose 4,6 dehydratase SPICA_RS03790 PF01546 Peptidase family M20/M25/M40 SPICA_RS03790 PF07687 Peptidase dimerisation domain SPICA_RS03795 PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase SPICA_RS03795 PF00925 GTP cyclohydrolase II SPICA_RS03805 PF01467 Cytidylyltransferase-like SPICA_RS03810 PF02608 ABC transporter substrate-binding protein PnrA-like SPICA_RS03815 PF00005 ABC transporter SPICA_RS03820 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS03825 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS03830 PF01048 Phosphorylase superfamily SPICA_RS03840 PF01475 Ferric uptake regulator family SPICA_RS03850 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS03860 PF01915 Glycosyl hydrolase family 3 C-terminal domain SPICA_RS03860 PF00933 Glycosyl hydrolase family 3 N terminal domain SPICA_RS03860 PF14310 Fibronectin type III-like domain SPICA_RS03865 PF16736 Single Cache-like SPICA_RS03865 PF00989 PAS fold SPICA_RS03865 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS03865 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS03870 PF00072 Response regulator receiver domain SPICA_RS03870 PF00486 Transcriptional regulatory protein, C terminal SPICA_RS03875 PF01895 PhoU domain SPICA_RS03880 PF13335 Magnesium chelatase, subunit ChlI C-terminal SPICA_RS03880 PF01078 Magnesium chelatase, subunit ChlI SPICA_RS03885 PF02811 PHP domain SPICA_RS03890 PF01979 Amidohydrolase family SPICA_RS03900 PF00027 Cyclic nucleotide-binding domain SPICA_RS03900 PF13545 Crp-like helix-turn-helix domain SPICA_RS03915 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS03915 PF12282 Signal transduction histidine kinase SPICA_RS03915 PF07568 Histidine kinase SPICA_RS03920 PF00128 Alpha amylase, catalytic domain SPICA_RS03920 PF11896 Domain of unknown function (DUF3416) SPICA_RS03925 PF00224 Pyruvate kinase, barrel domain SPICA_RS03925 PF00391 PEP-utilising enzyme, mobile domain SPICA_RS03925 PF02887 Pyruvate kinase, alpha/beta domain SPICA_RS03935 PF00156 Phosphoribosyl transferase domain SPICA_RS03960 PF05746 DALR anticodon binding domain SPICA_RS03960 PF00750 tRNA synthetases class I (R) SPICA_RS03960 PF03485 Arginyl tRNA synthetase N terminal domain SPICA_RS03965 PF00829 Ribosomal prokaryotic L21 protein SPICA_RS03975 PF01016 Ribosomal L27 protein SPICA_RS03980 PF01926 50S ribosome-binding GTPase SPICA_RS03980 PF01018 GTP1/OBG SPICA_RS03985 PF01467 Cytidylyltransferase-like SPICA_RS04005 PF00288 GHMP kinases N terminal domain SPICA_RS04005 PF08544 GHMP kinases C terminal SPICA_RS04010 PF04026 SpoVG SPICA_RS04020 PF01386 Ribosomal L25p family SPICA_RS04020 PF14693 Ribosomal protein TL5, C-terminal domain SPICA_RS04025 PF11734 TilS substrate C-terminal domain SPICA_RS04025 PF01171 PP-loop family SPICA_RS04030 PF17862 AAA+ lid domain SPICA_RS04030 PF06480 FtsH Extracellular SPICA_RS04030 PF01434 Peptidase family M41 SPICA_RS04030 PF00004 ATPase family associated with various cellular activities (AAA) SPICA_RS04040 PF13180 PDZ domain SPICA_RS04050 PF01627 Hpt domain SPICA_RS04050 PF07194 P2 response regulator binding domain SPICA_RS04050 PF02895 Signal transducing histidine kinase, homodimeric domain SPICA_RS04050 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS04050 PF01584 CheW-like domain SPICA_RS04055 PF03705 CheR methyltransferase, all-alpha domain SPICA_RS04055 PF01739 CheR methyltransferase, SAM binding domain SPICA_RS04060 PF01339 CheB methylesterase SPICA_RS04060 PF00072 Response regulator receiver domain SPICA_RS04065 PF00072 Response regulator receiver domain SPICA_RS04065 PF00486 Transcriptional regulatory protein, C terminal SPICA_RS04070 PF01584 CheW-like domain SPICA_RS04075 PF00072 Response regulator receiver domain SPICA_RS04075 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS04075 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS04075 PF08448 PAS fold SPICA_RS04075 PF13188 PAS domain SPICA_RS04085 PF06421 GTP-binding protein LepA C-terminus SPICA_RS04085 PF00679 Elongation factor G C-terminus SPICA_RS04085 PF14492 Elongation Factor G, domain II SPICA_RS04085 PF00009 Elongation factor Tu GTP binding domain SPICA_RS04085 PF03144 Elongation factor Tu domain 2 SPICA_RS04090 PF01973 Protein of unknown function DUF115 SPICA_RS04095 PF09312 SurA N-terminal domain SPICA_RS04095 PF00639 PPIC-type PPIASE domain SPICA_RS04100 PF10282 Lactonase, 7-bladed beta-propeller SPICA_RS04120 PF00248 Aldo/keto reductase family SPICA_RS04135 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS04140 PF05025 RbsD / FucU transport protein family SPICA_RS04145 PF00005 ABC transporter SPICA_RS04150 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS04155 PF13407 Periplasmic binding protein domain SPICA_RS04180 PF00756 Putative esterase SPICA_RS04180 PF00404 Dockerin type I domain SPICA_RS04180 PF03422 Carbohydrate binding module (family 6) SPICA_RS04180 PF00331 Glycosyl hydrolase family 10 SPICA_RS04185 PF00722 Glycosyl hydrolases family 16 SPICA_RS04200 PF01547 Bacterial extracellular solute-binding protein SPICA_RS04205 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS04210 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS04215 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS04220 PF03633 Glycosyl hydrolase family 65, C-terminal domain SPICA_RS04220 PF03632 Glycosyl hydrolase family 65 central catalytic domain SPICA_RS04220 PF03636 Glycosyl hydrolase family 65, N-terminal domain SPICA_RS04230 PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase SPICA_RS04230 PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase SPICA_RS04235 PF00334 Nucleoside diphosphate kinase SPICA_RS04240 PF13458 Periplasmic binding protein SPICA_RS04245 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS04250 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS04250 PF11862 Domain of unknown function (DUF3382) SPICA_RS04255 PF12399 Branched-chain amino acid ATP-binding cassette transporter SPICA_RS04255 PF00005 ABC transporter SPICA_RS04260 PF00005 ABC transporter SPICA_RS04265 PF00171 Aldehyde dehydrogenase family SPICA_RS04270 PF00696 Amino acid kinase family SPICA_RS04275 PF14748 Pyrroline-5-carboxylate reductase dimerisation SPICA_RS04275 PF03807 NADP oxidoreductase coenzyme F420-dependent SPICA_RS04285 PF00933 Glycosyl hydrolase family 3 N terminal domain SPICA_RS04285 PF01915 Glycosyl hydrolase family 3 C-terminal domain SPICA_RS04290 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPICA_RS04295 PF02743 Cache domain SPICA_RS04295 PF00672 HAMP domain SPICA_RS04295 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS04310 PF03979 Sigma-70 factor, region 1.1 SPICA_RS04310 PF04545 Sigma-70, region 4 SPICA_RS04310 PF04539 Sigma-70 region 3 SPICA_RS04310 PF04542 Sigma-70 region 2 SPICA_RS04310 PF00140 Sigma-70 factor, region 1.2 SPICA_RS04320 PF00814 Glycoprotease family SPICA_RS04330 PF00679 Elongation factor G C-terminus SPICA_RS04330 PF14492 Elongation Factor G, domain II SPICA_RS04330 PF03764 Elongation factor G, domain IV SPICA_RS04330 PF00009 Elongation factor Tu GTP binding domain SPICA_RS04330 PF03144 Elongation factor Tu domain 2 SPICA_RS04335 PF02195 ParB-like nuclease domain SPICA_RS04335 PF17762 HTH domain found in ParB protein SPICA_RS04340 PF00912 Transglycosylase SPICA_RS04340 PF17092 Penicillin-binding protein OB-like domain SPICA_RS04340 PF00905 Penicillin binding protein transpeptidase domain SPICA_RS04380 PF06415 BPG-independent PGAM N-terminus (iPGM_N) SPICA_RS04380 PF01676 Metalloenzyme superfamily SPICA_RS04390 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPICA_RS04390 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPICA_RS04420 PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L SPICA_RS04425 PF00361 Proton-conducting membrane transporter SPICA_RS04440 PF00535 Glycosyl transferase family 2 SPICA_RS04445 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SPICA_RS04445 PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain SPICA_RS04445 PF02142 MGS-like domain SPICA_RS04450 PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain SPICA_RS04450 PF00117 Glutamine amidotransferase class-I SPICA_RS04455 PF04073 Aminoacyl-tRNA editing domain SPICA_RS04460 PF01613 Flavin reductase like domain SPICA_RS04460 PF00753 Metallo-beta-lactamase superfamily SPICA_RS04465 PF00563 EAL domain SPICA_RS04465 PF00990 Diguanylate cyclase, GGDEF domain SPICA_RS04465 PF03707 Bacterial signalling protein N terminal repeat SPICA_RS04470 PF00072 Response regulator receiver domain SPICA_RS04490 PF01960 ArgJ family SPICA_RS04495 PF00696 Amino acid kinase family SPICA_RS04500 PF00202 Aminotransferase class-III SPICA_RS04505 PF00764 Arginosuccinate synthase SPICA_RS04510 PF00206 Lyase SPICA_RS04510 PF14698 Argininosuccinate lyase C-terminal SPICA_RS04520 PF08240 Alcohol dehydrogenase GroES-like domain SPICA_RS04520 PF00107 Zinc-binding dehydrogenase SPICA_RS04525 PF00749 tRNA synthetases class I (E and Q), catalytic domain SPICA_RS04535 PF00491 Arginase family SPICA_RS04550 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPICA_RS04550 PF03129 Anticodon binding domain SPICA_RS04565 PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain SPICA_RS04565 PF02142 MGS-like domain SPICA_RS04565 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SPICA_RS04585 PF00872 Transposase, Mutator family SPICA_RS04610 PF01381 Helix-turn-helix SPICA_RS04635 PF12146 Serine aminopeptidase, S33 SPICA_RS04650 PF01791 DeoC/LacD family aldolase SPICA_RS04655 PF02608 ABC transporter substrate-binding protein PnrA-like SPICA_RS04660 PF00005 ABC transporter SPICA_RS04665 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS04670 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS04675 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SPICA_RS04675 PF01411 tRNA synthetases class II (A) SPICA_RS04680 PF13145 PPIC-type PPIASE domain SPICA_RS04685 PF01029 NusB family SPICA_RS04695 PF00166 Chaperonin 10 Kd subunit SPICA_RS04705 PF04542 Sigma-70 region 2 SPICA_RS04705 PF04539 Sigma-70 region 3 SPICA_RS04705 PF03979 Sigma-70 factor, region 1.1 SPICA_RS04705 PF00140 Sigma-70 factor, region 1.2 SPICA_RS04705 PF04545 Sigma-70, region 4 SPICA_RS04710 PF03590 Aspartate-ammonia ligase SPICA_RS04715 PF00392 Bacterial regulatory proteins, gntR family SPICA_RS04715 PF00155 Aminotransferase class I and II SPICA_RS04720 PF01680 SOR/SNZ family SPICA_RS04725 PF01174 SNO glutamine amidotransferase family SPICA_RS04735 PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SPICA_RS04735 PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SPICA_RS04750 PF00085 Thioredoxin SPICA_RS04755 PF01381 Helix-turn-helix SPICA_RS04760 PF00330 Aconitase family (aconitate hydratase) SPICA_RS04765 PF00694 Aconitase C-terminal domain SPICA_RS04770 PF12832 MFS_1 like family SPICA_RS04775 PF04474 Protein of unknown function (DUF554) SPICA_RS04780 PF00005 ABC transporter SPICA_RS04780 PF17912 MalK OB fold domain SPICA_RS04780 PF03459 TOBE domain SPICA_RS04785 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS04790 PF03975 CheD chemotactic sensory transduction SPICA_RS04795 PF00773 RNB domain SPICA_RS04800 PF01842 ACT domain SPICA_RS04800 PF00696 Amino acid kinase family SPICA_RS04805 PF01113 Dihydrodipicolinate reductase, N-terminus SPICA_RS04805 PF05173 Dihydrodipicolinate reductase, C-terminus SPICA_RS04810 PF00701 Dihydrodipicolinate synthetase family SPICA_RS04815 PF02774 Semialdehyde dehydrogenase, dimerisation domain SPICA_RS04815 PF01118 Semialdehyde dehydrogenase, NAD binding domain SPICA_RS04820 PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SPICA_RS04820 PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain SPICA_RS04825 PF00155 Aminotransferase class I and II SPICA_RS04835 PF13333 Integrase core domain SPICA_RS04835 PF00665 Integrase core domain SPICA_RS04835 PF13276 HTH-like domain SPICA_RS04855 PF02895 Signal transducing histidine kinase, homodimeric domain SPICA_RS04855 PF07194 P2 response regulator binding domain SPICA_RS04855 PF01627 Hpt domain SPICA_RS04855 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS04855 PF01584 CheW-like domain SPICA_RS04860 PF01584 CheW-like domain SPICA_RS04870 PF00072 Response regulator receiver domain SPICA_RS04880 PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain SPICA_RS04880 PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain SPICA_RS04890 PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SPICA_RS04890 PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain SPICA_RS04900 PF08207 Elongation factor P (EF-P) KOW-like domain SPICA_RS04900 PF01132 Elongation factor P (EF-P) OB domain SPICA_RS04900 PF09285 Elongation factor P, C-terminal SPICA_RS04905 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS04905 PF08447 PAS fold SPICA_RS04905 PF08448 PAS fold SPICA_RS04910 PF00158 Sigma-54 interaction domain SPICA_RS04910 PF02954 Bacterial regulatory protein, Fis family SPICA_RS04910 PF00072 Response regulator receiver domain SPICA_RS04915 PF01206 Sulfurtransferase TusA SPICA_RS04920 PF04143 Sulphur transport SPICA_RS04925 PF04143 Sulphur transport SPICA_RS04930 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPICA_RS04935 PF10609 NUBPL iron-transfer P-loop NTPase SPICA_RS04945 PF00232 Glycosyl hydrolase family 1 SPICA_RS04950 PF00480 ROK family SPICA_RS04955 PF00152 tRNA synthetases class II (D, K and N) SPICA_RS04960 PF08245 Mur ligase middle domain SPICA_RS04960 PF02875 Mur ligase family, glutamate ligase domain SPICA_RS04985 PF01820 D-ala D-ala ligase N-terminus SPICA_RS04985 PF07478 D-ala D-ala ligase C-terminus SPICA_RS04990 PF01225 Mur ligase family, catalytic domain SPICA_RS04990 PF02875 Mur ligase family, glutamate ligase domain SPICA_RS04990 PF08245 Mur ligase middle domain SPICA_RS05000 PF01871 AMMECR1 SPICA_RS05010 PF01425 Amidase SPICA_RS05015 PF02934 GatB/GatE catalytic domain SPICA_RS05015 PF02637 GatB domain SPICA_RS05020 PF01336 OB-fold nucleic acid binding domain SPICA_RS05020 PF00152 tRNA synthetases class II (D, K and N) SPICA_RS05035 PF01814 Hemerythrin HHE cation binding domain SPICA_RS05070 PF00211 Adenylate and Guanylate cyclase catalytic domain SPICA_RS05115 PF05448 Acetyl xylan esterase (AXE1) SPICA_RS05130 PF08267 Cobalamin-independent synthase, N-terminal domain SPICA_RS05130 PF01717 Cobalamin-independent synthase, Catalytic domain SPICA_RS05135 PF00933 Glycosyl hydrolase family 3 N terminal domain SPICA_RS05140 PF00849 RNA pseudouridylate synthase SPICA_RS05140 PF01479 S4 domain SPICA_RS05145 PF01136 Peptidase family U32 SPICA_RS05155 PF01842 ACT domain SPICA_RS05160 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS05160 PF13426 PAS domain SPICA_RS05160 PF00672 HAMP domain SPICA_RS05170 PF00294 pfkB family carbohydrate kinase SPICA_RS05175 PF01554 MatE SPICA_RS05195 PF01551 Peptidase family M23 SPICA_RS05195 PF01476 LysM domain SPICA_RS05200 PF00140 Sigma-70 factor, region 1.2 SPICA_RS05200 PF03979 Sigma-70 factor, region 1.1 SPICA_RS05200 PF04545 Sigma-70, region 4 SPICA_RS05200 PF04539 Sigma-70 region 3 SPICA_RS05200 PF04542 Sigma-70 region 2 SPICA_RS05205 PF00929 Exonuclease SPICA_RS05210 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPICA_RS05210 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SPICA_RS05210 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SPICA_RS05210 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SPICA_RS05220 PF00364 Biotin-requiring enzyme SPICA_RS05220 PF00682 HMGL-like SPICA_RS05220 PF02436 Conserved carboxylase domain SPICA_RS05225 PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit SPICA_RS05230 PF00156 Phosphoribosyl transferase domain SPICA_RS05250 PF01351 Ribonuclease HII SPICA_RS05260 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPICA_RS05260 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SPICA_RS05260 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SPICA_RS05260 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SPICA_RS05285 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPICA_RS05290 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPICA_RS05305 PF01479 S4 domain SPICA_RS05305 PF00849 RNA pseudouridylate synthase SPICA_RS05315 PF03065 Glycosyl hydrolase family 57 SPICA_RS05315 PF09210 Domain of unknown function (DUF1957) SPICA_RS05330 PF00672 HAMP domain SPICA_RS05330 PF07228 Stage II sporulation protein E (SpoIIE) SPICA_RS05345 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS05350 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS05390 PF00873 AcrB/AcrD/AcrF family SPICA_RS05395 PF00873 AcrB/AcrD/AcrF family SPICA_RS05485 PF00872 Transposase, Mutator family SPICA_RS05505 PF01171 PP-loop family SPICA_RS05520 PF01966 HD domain SPICA_RS05525 PF00330 Aconitase family (aconitate hydratase) SPICA_RS05545 PF01740 STAS domain SPICA_RS05555 PF12848 ABC transporter SPICA_RS05555 PF00005 ABC transporter SPICA_RS05560 PF03006 Haemolysin-III related SPICA_RS05565 PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ SPICA_RS05590 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SPICA_RS05590 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SPICA_RS05605 PF06463 Molybdenum Cofactor Synthesis C SPICA_RS05605 PF04055 Radical SAM superfamily SPICA_RS05620 PF03477 ATP cone domain SPICA_RS05625 PF00862 Sucrose synthase SPICA_RS05625 PF00534 Glycosyl transferases group 1 SPICA_RS05630 PF02190 ATP-dependent protease La (LON) substrate-binding domain SPICA_RS05630 PF00004 ATPase family associated with various cellular activities (AAA) SPICA_RS05630 PF05362 Lon protease (S16) C-terminal proteolytic domain SPICA_RS05635 PF06689 ClpX C4-type zinc finger SPICA_RS05635 PF10431 C-terminal, D2-small domain, of ClpB protein SPICA_RS05635 PF07724 AAA domain (Cdc48 subfamily) SPICA_RS05640 PF00574 Clp protease SPICA_RS05645 PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase SPICA_RS05645 PF05698 Bacterial trigger factor protein (TF) C-terminus SPICA_RS05645 PF05697 Bacterial trigger factor protein (TF) SPICA_RS05690 PF07196 Flagellin hook IN motif SPICA_RS05690 PF06429 Flagellar basal body rod FlgEFG protein C-terminal SPICA_RS05695 PF00669 Bacterial flagellin N-terminal helical region SPICA_RS05695 PF00700 Bacterial flagellin C-terminal helical region SPICA_RS05700 PF02623 FliW protein SPICA_RS05705 PF02599 Global regulator protein family SPICA_RS05710 PF01966 HD domain SPICA_RS05710 PF00672 HAMP domain SPICA_RS05715 PF00814 Glycoprotease family SPICA_RS05720 PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE SPICA_RS05740 PF07195 Flagellar hook-associated protein 2 C-terminus SPICA_RS05740 PF02465 Flagellar hook-associated protein 2 N-terminus SPICA_RS05745 PF03646 FlaG protein SPICA_RS05750 PF00669 Bacterial flagellin N-terminal helical region SPICA_RS05750 PF00700 Bacterial flagellin C-terminal helical region SPICA_RS05755 PF00669 Bacterial flagellin N-terminal helical region SPICA_RS05755 PF00700 Bacterial flagellin C-terminal helical region SPICA_RS05765 PF12002 MgsA AAA+ ATPase C terminal SPICA_RS05765 PF00004 ATPase family associated with various cellular activities (AAA) SPICA_RS05765 PF16193 AAA C-terminal domain SPICA_RS05780 PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SPICA_RS05780 PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SPICA_RS05785 PF02649 Type I GTP cyclohydrolase folE2 SPICA_RS05795 PF01938 TRAM domain SPICA_RS05795 PF00919 Uncharacterized protein family UPF0004 SPICA_RS05795 PF04055 Radical SAM superfamily SPICA_RS05815 PF02272 DHHA1 domain SPICA_RS05815 PF01368 DHH family SPICA_RS05835 PF00391 PEP-utilising enzyme, mobile domain SPICA_RS05835 PF02896 PEP-utilising enzyme, TIM barrel domain SPICA_RS05850 PF01515 Phosphate acetyl/butaryl transferase SPICA_RS05870 PF00919 Uncharacterized protein family UPF0004 SPICA_RS05870 PF04055 Radical SAM superfamily SPICA_RS05890 PF01661 Macro domain SPICA_RS05895 PF02594 Uncharacterised ACR, YggU family COG1872 SPICA_RS05915 PF00753 Metallo-beta-lactamase superfamily SPICA_RS05930 PF01177 Asp/Glu/Hydantoin racemase SPICA_RS05935 PF03193 RsgA GTPase SPICA_RS05935 PF16745 RsgA N-terminal domain SPICA_RS05940 PF00488 MutS domain V SPICA_RS05940 PF01713 Smr domain SPICA_RS05955 PF02863 Arginine repressor, C-terminal domain SPICA_RS05955 PF01316 Arginine repressor, DNA binding domain SPICA_RS05960 PF00342 Phosphoglucose isomerase SPICA_RS05975 PF01430 Hsp33 protein SPICA_RS06005 PF01594 AI-2E family transporter SPICA_RS06015 PF05167 Uncharacterised ACR (DUF711) SPICA_RS06020 PF10576 Iron-sulfur binding domain of endonuclease III SPICA_RS06020 PF00633 Helix-hairpin-helix motif SPICA_RS06020 PF00730 HhH-GPD superfamily base excision DNA repair protein SPICA_RS06025 PF00133 tRNA synthetases class I (I, L, M and V) SPICA_RS06025 PF08264 Anticodon-binding domain of tRNA SPICA_RS06055 PF01625 Peptide methionine sulfoxide reductase SPICA_RS06065 PF05681 Fumarate hydratase (Fumerase) SPICA_RS06065 PF05683 Fumarase C-terminus SPICA_RS06075 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS06075 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS06075 PF00989 PAS fold SPICA_RS06080 PF00072 Response regulator receiver domain SPICA_RS06080 PF00158 Sigma-54 interaction domain SPICA_RS06080 PF02954 Bacterial regulatory protein, Fis family SPICA_RS06090 PF01145 SPFH domain / Band 7 family SPICA_RS06095 PF01145 SPFH domain / Band 7 family SPICA_RS06100 PF01192 RNA polymerase Rpb6 SPICA_RS06110 PF02780 Transketolase, C-terminal domain SPICA_RS06110 PF13292 1-deoxy-D-xylulose-5-phosphate synthase SPICA_RS06110 PF02779 Transketolase, pyrimidine binding domain SPICA_RS06115 PF00809 Pterin binding enzyme SPICA_RS06120 PF02457 DisA bacterial checkpoint controller nucleotide-binding SPICA_RS06125 PF07949 YbbR-like protein SPICA_RS06130 PF01648 4'-phosphopantetheinyl transferase superfamily SPICA_RS06140 PF01416 tRNA pseudouridine synthase SPICA_RS06145 PF01497 Periplasmic binding protein SPICA_RS06150 PF01032 FecCD transport family SPICA_RS06155 PF00005 ABC transporter SPICA_RS06160 PF01063 Amino-transferase class IV SPICA_RS06165 PF00266 Aminotransferase class-V SPICA_RS06180 PF01595 Cyclin M transmembrane N-terminal domain SPICA_RS06180 PF00571 CBS domain SPICA_RS06180 PF03471 Transporter associated domain SPICA_RS06195 PF00155 Aminotransferase class I and II SPICA_RS06205 PF03717 Penicillin-binding Protein dimerisation domain SPICA_RS06205 PF00905 Penicillin binding protein transpeptidase domain SPICA_RS06210 PF10502 Signal peptidase, peptidase S26 SPICA_RS06215 PF01551 Peptidase family M23 SPICA_RS06220 PF02562 PhoH-like protein SPICA_RS06220 PF13638 PIN domain SPICA_RS06230 PF01522 Polysaccharide deacetylase SPICA_RS06240 PF17760 UvrA interaction domain SPICA_RS06240 PF00005 ABC transporter SPICA_RS06240 PF17755 UvrA DNA-binding domain SPICA_RS06245 PF04453 LPS transport system D SPICA_RS06245 PF03968 OstA-like protein SPICA_RS06250 PF02562 PhoH-like protein SPICA_RS06255 PF01966 HD domain SPICA_RS06255 PF07698 7TM receptor with intracellular HD hydrolase SPICA_RS06255 PF07697 7TM-HD extracellular SPICA_RS06260 PF02130 Uncharacterized protein family UPF0054 SPICA_RS06265 PF03471 Transporter associated domain SPICA_RS06265 PF00571 CBS domain SPICA_RS06285 PF00472 RF-1 domain SPICA_RS06285 PF03462 PCRF domain SPICA_RS06295 PF00448 SRP54-type protein, GTPase domain SPICA_RS06295 PF02881 SRP54-type protein, helical bundle domain SPICA_RS06305 PF02687 FtsX-like permease family SPICA_RS06305 PF12704 MacB-like periplasmic core domain SPICA_RS06310 PF00005 ABC transporter SPICA_RS06325 PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain SPICA_RS06330 PF17871 AAA lid domain SPICA_RS06330 PF10431 C-terminal, D2-small domain, of ClpB protein SPICA_RS06330 PF02861 Clp amino terminal domain, pathogenicity island component SPICA_RS06330 PF07724 AAA domain (Cdc48 subfamily) SPICA_RS06330 PF00004 ATPase family associated with various cellular activities (AAA) SPICA_RS06335 PF01557 Fumarylacetoacetate (FAA) hydrolase family SPICA_RS06345 PF00255 Glutathione peroxidase SPICA_RS06350 PF01047 MarR family SPICA_RS06355 PF00483 Nucleotidyl transferase SPICA_RS06360 PF00270 DEAD/DEAH box helicase SPICA_RS06360 PF00271 Helicase conserved C-terminal domain SPICA_RS06360 PF09369 Domain of unknown function (DUF1998) SPICA_RS06370 PF00580 UvrD/REP helicase N-terminal domain SPICA_RS06370 PF13361 UvrD-like helicase C-terminal domain SPICA_RS06380 PF03600 Citrate transporter SPICA_RS06385 PF01725 Ham1 family SPICA_RS06405 PF00270 DEAD/DEAH box helicase SPICA_RS06405 PF00271 Helicase conserved C-terminal domain SPICA_RS06410 PF13439 Glycosyltransferase Family 4 SPICA_RS06410 PF00534 Glycosyl transferases group 1 SPICA_RS06415 PF00474 Sodium:solute symporter family SPICA_RS06430 PF00501 AMP-binding enzyme SPICA_RS06430 PF14535 AMP-binding enzyme C-terminal domain SPICA_RS06435 PF00501 AMP-binding enzyme SPICA_RS06435 PF14535 AMP-binding enzyme C-terminal domain SPICA_RS06445 PF08323 Starch synthase catalytic domain SPICA_RS06445 PF00534 Glycosyl transferases group 1 SPICA_RS06460 PF05958 tRNA (Uracil-5-)-methyltransferase SPICA_RS06465 PF12146 Serine aminopeptidase, S33 SPICA_RS06470 PF12626 Polymerase A arginine-rich C-terminus SPICA_RS06470 PF01743 Poly A polymerase head domain SPICA_RS06470 PF12627 Probable RNA and SrmB- binding site of polymerase A SPICA_RS06485 PF01479 S4 domain SPICA_RS06485 PF00849 RNA pseudouridylate synthase SPICA_RS06505 PF03116 NQR2, RnfD, RnfE family SPICA_RS06530 PF01588 Putative tRNA binding domain SPICA_RS06530 PF09334 tRNA synthetases class I (M) SPICA_RS06540 PF12706 Beta-lactamase superfamily domain SPICA_RS06540 PF00753 Metallo-beta-lactamase superfamily SPICA_RS06545 PF13732 Domain of unknown function (DUF4162) SPICA_RS06545 PF00005 ABC transporter SPICA_RS06605 PF01668 SmpB protein SPICA_RS06615 PF10502 Signal peptidase, peptidase S26 SPICA_RS06625 PF06969 HemN C-terminal domain SPICA_RS06625 PF04055 Radical SAM superfamily SPICA_RS06630 PF00270 DEAD/DEAH box helicase SPICA_RS06630 PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold SPICA_RS06630 PF00271 Helicase conserved C-terminal domain SPICA_RS06630 PF04408 Helicase associated domain (HA2) SPICA_RS06635 PF00391 PEP-utilising enzyme, mobile domain SPICA_RS06635 PF02896 PEP-utilising enzyme, TIM barrel domain SPICA_RS06635 PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain SPICA_RS06650 PF00005 ABC transporter SPICA_RS06660 PF00005 ABC transporter SPICA_RS06665 PF02632 BioY family SPICA_RS06670 PF03099 Biotin/lipoate A/B protein ligase family SPICA_RS06670 PF08279 HTH domain SPICA_RS06670 PF02237 Biotin protein ligase C terminal domain SPICA_RS06675 PF00795 Carbon-nitrogen hydrolase SPICA_RS06680 PF10509 Galactokinase galactose-binding signature SPICA_RS06680 PF08544 GHMP kinases C terminal SPICA_RS06695 PF00085 Thioredoxin SPICA_RS06700 PF02568 Thiamine biosynthesis protein (ThiI) SPICA_RS06700 PF02926 THUMP domain SPICA_RS06705 PF00266 Aminotransferase class-V SPICA_RS06715 PF03447 Homoserine dehydrogenase, NAD binding domain SPICA_RS06715 PF00742 Homoserine dehydrogenase SPICA_RS06715 PF13840 ACT domain SPICA_RS06715 PF01842 ACT domain SPICA_RS06715 PF00696 Amino acid kinase family SPICA_RS06720 PF00155 Aminotransferase class I and II SPICA_RS06730 PF00953 Glycosyl transferase family 4 SPICA_RS06740 PF13333 Integrase core domain SPICA_RS06740 PF13276 HTH-like domain SPICA_RS06740 PF00665 Integrase core domain SPICA_RS06745 PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase SPICA_RS06750 PF04321 RmlD substrate binding domain SPICA_RS06755 PF16363 GDP-mannose 4,6 dehydratase SPICA_RS06775 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPICA_RS06775 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SPICA_RS06780 PF00266 Aminotransferase class-V SPICA_RS06785 PF13393 Histidyl-tRNA synthetase SPICA_RS06790 PF03309 Type III pantothenate kinase SPICA_RS06800 PF08666 SAF domain SPICA_RS06800 PF03102 NeuB family SPICA_RS06810 PF01709 Transcriptional regulator SPICA_RS06815 PF02075 Crossover junction endodeoxyribonuclease RuvC SPICA_RS06820 PF01330 RuvA N terminal domain SPICA_RS06825 PF17864 RuvB AAA lid domain SPICA_RS06825 PF05496 Holliday junction DNA helicase RuvB P-loop domain SPICA_RS06825 PF05491 RuvB C-terminal winged helix domain SPICA_RS06830 PF02547 Queuosine biosynthesis protein SPICA_RS06840 PF02223 Thymidylate kinase SPICA_RS06850 PF01103 Surface antigen SPICA_RS06850 PF07244 Surface antigen variable number repeat SPICA_RS06865 PF05190 MutS family domain IV SPICA_RS06865 PF01624 MutS domain I SPICA_RS06865 PF00488 MutS domain V SPICA_RS06865 PF05188 MutS domain II SPICA_RS06865 PF05192 MutS domain III SPICA_RS06870 PF00156 Phosphoribosyl transferase domain SPICA_RS06875 PF02576 RimP N-terminal domain SPICA_RS06875 PF17384 RimP C-terminal SH3 domain SPICA_RS06880 PF00575 S1 RNA binding domain SPICA_RS06880 PF08529 NusA N-terminal domain SPICA_RS06880 PF13184 NusA-like KH domain SPICA_RS06885 PF00009 Elongation factor Tu GTP binding domain SPICA_RS06885 PF11987 Translation-initiation factor 2 SPICA_RS06885 PF04760 Translation initiation factor IF-2, N-terminal region SPICA_RS06890 PF02033 Ribosome-binding factor A SPICA_RS06895 PF01509 TruB family pseudouridylate synthase (N terminal domain) SPICA_RS06900 PF00312 Ribosomal protein S15 SPICA_RS06905 PF00013 KH domain SPICA_RS06905 PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain SPICA_RS06905 PF01138 3' exoribonuclease family, domain 1 SPICA_RS06905 PF03725 3' exoribonuclease family, domain 2 SPICA_RS06905 PF00575 S1 RNA binding domain SPICA_RS06910 PF05193 Peptidase M16 inactive domain SPICA_RS06910 PF00675 Insulinase (Peptidase family M16) SPICA_RS06925 PF01702 Queuine tRNA-ribosyltransferase SPICA_RS06950 PF00834 Ribulose-phosphate 3 epimerase family SPICA_RS06970 PF02580 D-Tyr-tRNA(Tyr) deacylase SPICA_RS06975 PF13793 N-terminal domain of ribose phosphate pyrophosphokinase SPICA_RS06975 PF14572 Phosphoribosyl synthetase-associated domain SPICA_RS06980 PF00154 recA bacterial DNA recombination protein SPICA_RS06990 PF02616 Segregation and condensation protein ScpA SPICA_RS06995 PF04079 Segregation and condensation complex subunit ScpB SPICA_RS07000 PF00849 RNA pseudouridylate synthase SPICA_RS07000 PF01479 S4 domain SPICA_RS07005 PF02224 Cytidylate kinase SPICA_RS07010 PF00575 S1 RNA binding domain SPICA_RS07015 PF13185 GAF domain SPICA_RS07015 PF00158 Sigma-54 interaction domain SPICA_RS07015 PF02954 Bacterial regulatory protein, Fis family SPICA_RS07025 PF00211 Adenylate and Guanylate cyclase catalytic domain SPICA_RS07040 PF01098 Cell cycle protein SPICA_RS07045 PF00905 Penicillin binding protein transpeptidase domain SPICA_RS07045 PF03717 Penicillin-binding Protein dimerisation domain SPICA_RS07055 PF04085 rod shape-determining protein MreC SPICA_RS07075 PF03979 Sigma-70 factor, region 1.1 SPICA_RS07075 PF04539 Sigma-70 region 3 SPICA_RS07075 PF04545 Sigma-70, region 4 SPICA_RS07075 PF04542 Sigma-70 region 2 SPICA_RS07075 PF00140 Sigma-70 factor, region 1.2 SPICA_RS07080 PF01807 CHC2 zinc finger SPICA_RS07080 PF08275 DNA primase catalytic core, N-terminal domain SPICA_RS07085 PF02618 YceG-like family SPICA_RS07090 PF02225 PA domain SPICA_RS07090 PF06280 Fn3-like domain SPICA_RS07090 PF00082 Subtilase family SPICA_RS07100 PF00753 Metallo-beta-lactamase superfamily SPICA_RS07130 PF01230 HIT domain SPICA_RS07140 PF01743 Poly A polymerase head domain SPICA_RS07140 PF12627 Probable RNA and SrmB- binding site of polymerase A SPICA_RS07140 PF13735 tRNA nucleotidyltransferase domain 2 putative SPICA_RS07145 PF00035 Double-stranded RNA binding motif SPICA_RS07145 PF14622 Ribonuclease-III-like SPICA_RS07150 PF00550 Phosphopantetheine attachment site SPICA_RS07155 PF01467 Cytidylyltransferase-like SPICA_RS07180 PF01336 OB-fold nucleic acid binding domain SPICA_RS07180 PF17657 Bacterial DNA polymerase III alpha subunit finger domain SPICA_RS07180 PF07733 Bacterial DNA polymerase III alpha NTPase domain SPICA_RS07180 PF02811 PHP domain SPICA_RS07180 PF14579 Helix-hairpin-helix motif SPICA_RS07185 PF00211 Adenylate and Guanylate cyclase catalytic domain SPICA_RS07185 PF00672 HAMP domain SPICA_RS07195 PF02545 Maf-like protein SPICA_RS07200 PF00318 Ribosomal protein S2 SPICA_RS07205 PF00889 Elongation factor TS SPICA_RS07210 PF01765 Ribosome recycling factor SPICA_RS07215 PF01255 Putative undecaprenyl diphosphate synthase SPICA_RS07225 PF13288 DXP reductoisomerase C-terminal domain SPICA_RS07225 PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase SPICA_RS07225 PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain SPICA_RS07230 PF17820 PDZ domain SPICA_RS07230 PF02163 Peptidase family M50 SPICA_RS07245 PF03796 DnaB-like helicase C terminal domain SPICA_RS07245 PF00772 DnaB-like helicase N terminal domain SPICA_RS07250 PF03948 Ribosomal protein L9, C-terminal domain SPICA_RS07250 PF01281 Ribosomal protein L9, N-terminal domain SPICA_RS07260 PF01084 Ribosomal protein S18 SPICA_RS07265 PF00436 Single-strand binding protein family SPICA_RS07270 PF01250 Ribosomal protein S6 SPICA_RS07285 PF13847 Methyltransferase domain SPICA_RS07300 PF04055 Radical SAM superfamily SPICA_RS07305 PF04286 Protein of unknown function (DUF445) SPICA_RS07315 PF00293 NUDIX domain SPICA_RS07330 PF03853 YjeF-related protein N-terminus SPICA_RS07330 PF01256 Carbohydrate kinase SPICA_RS07340 PF07516 SecA Wing and Scaffold domain SPICA_RS07340 PF01043 SecA preprotein cross-linking domain SPICA_RS07340 PF07517 SecA DEAD-like domain SPICA_RS07340 PF02810 SEC-C motif SPICA_RS07360 PF02719 Polysaccharide biosynthesis protein SPICA_RS07365 PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family SPICA_RS07370 PF01799 [2Fe-2S] binding domain SPICA_RS07370 PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase SPICA_RS07370 PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SPICA_RS07370 PF00111 2Fe-2S iron-sulfur cluster binding domain SPICA_RS07375 PF00111 2Fe-2S iron-sulfur cluster binding domain SPICA_RS07375 PF01799 [2Fe-2S] binding domain SPICA_RS07390 PF01761 3-dehydroquinate synthase SPICA_RS07400 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SPICA_RS07400 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain SPICA_RS07400 PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SPICA_RS07405 PF00005 ABC transporter SPICA_RS07405 PF00664 ABC transporter transmembrane region SPICA_RS07430 PF04991 LicD family SPICA_RS07470 PF01370 NAD dependent epimerase/dehydratase family SPICA_RS07475 PF02397 Bacterial sugar transferase SPICA_RS07490 PF00460 Flagella basal body rod protein SPICA_RS07490 PF06429 Flagellar basal body rod FlgEFG protein C-terminal SPICA_RS07495 PF06429 Flagellar basal body rod FlgEFG protein C-terminal SPICA_RS07495 PF00460 Flagella basal body rod protein SPICA_RS07505 PF04204 Homoserine O-succinyltransferase SPICA_RS07510 PF00270 DEAD/DEAH box helicase SPICA_RS07510 PF00271 Helicase conserved C-terminal domain SPICA_RS07510 PF08482 ATP-dependent helicase C-terminal SPICA_RS07510 PF04408 Helicase associated domain (HA2) SPICA_RS07525 PF00533 BRCA1 C Terminus (BRCT) domain SPICA_RS07525 PF01653 NAD-dependent DNA ligase adenylation domain SPICA_RS07525 PF03120 NAD-dependent DNA ligase OB-fold domain SPICA_RS07530 PF02390 Putative methyltransferase SPICA_RS07615 PF04551 GcpE protein SPICA_RS07630 PF01813 ATP synthase subunit D SPICA_RS07635 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPICA_RS07635 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPICA_RS07640 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPICA_RS07640 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPICA_RS07640 PF16886 ATPsynthase alpha/beta subunit N-term extension SPICA_RS07650 PF01991 ATP synthase (E/31 kDa) subunit SPICA_RS07660 PF01263 Aldose 1-epimerase SPICA_RS07665 PF00226 DnaJ domain SPICA_RS07670 PF00158 Sigma-54 interaction domain SPICA_RS07670 PF00072 Response regulator receiver domain SPICA_RS07670 PF02954 Bacterial regulatory protein, Fis family SPICA_RS07675 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS07675 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS07675 PF13426 PAS domain SPICA_RS07675 PF13188 PAS domain SPICA_RS07675 PF00989 PAS fold SPICA_RS07680 PF12169 DNA polymerase III subunits gamma and tau domain III SPICA_RS07685 PF02674 Colicin V production protein SPICA_RS07690 PF03033 Glycosyltransferase family 28 N-terminal domain SPICA_RS07690 PF04101 Glycosyltransferase family 28 C-terminal domain SPICA_RS07715 PF01584 CheW-like domain SPICA_RS07735 PF04539 Sigma-70 region 3 SPICA_RS07735 PF04542 Sigma-70 region 2 SPICA_RS07735 PF04545 Sigma-70, region 4 SPICA_RS07745 PF10609 NUBPL iron-transfer P-loop NTPase SPICA_RS07750 PF00448 SRP54-type protein, GTPase domain SPICA_RS07755 PF00771 FHIPEP family SPICA_RS07760 PF01312 FlhB HrpN YscU SpaS Family SPICA_RS07765 PF01311 Bacterial export proteins, family 1 SPICA_RS07770 PF01313 Bacterial export proteins, family 3 SPICA_RS07775 PF00813 FliP family SPICA_RS07785 PF01052 Type III flagellar switch regulator (C-ring) FliN C-term SPICA_RS07785 PF04509 CheC-like family SPICA_RS07790 PF02154 Flagellar motor switch protein FliM SPICA_RS07790 PF01052 Type III flagellar switch regulator (C-ring) FliN C-term SPICA_RS07795 PF03748 Flagellar basal body-associated protein FliL SPICA_RS07800 PF00691 OmpA family SPICA_RS07800 PF13677 Membrane MotB of proton-channel complex MotA/MotB SPICA_RS07805 PF01618 MotA/TolQ/ExbB proton channel family SPICA_RS07810 PF06289 Flagellar and Swarming motility proteins SPICA_RS07815 PF07559 Flagellar basal body protein FlaE SPICA_RS07815 PF00460 Flagella basal body rod protein SPICA_RS07815 PF06429 Flagellar basal body rod FlgEFG protein C-terminal SPICA_RS07820 PF03963 Flagellar hook capping protein - N-terminal region SPICA_RS07840 PF04227 Indigoidine synthase A like protein SPICA_RS07845 PF00294 pfkB family carbohydrate kinase SPICA_RS07855 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPICA_RS07855 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPICA_RS07860 PF00696 Amino acid kinase family SPICA_RS07860 PF01842 ACT domain SPICA_RS07860 PF13840 ACT domain SPICA_RS07860 PF00742 Homoserine dehydrogenase SPICA_RS07860 PF03447 Homoserine dehydrogenase, NAD binding domain SPICA_RS07880 PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system SPICA_RS07885 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SPICA_RS07890 PF03167 Uracil DNA glycosylase superfamily SPICA_RS07895 PF00270 DEAD/DEAH box helicase SPICA_RS07895 PF18074 Primosomal protein N C-terminal domain SPICA_RS07895 PF18319 PriA DNA helicase Cys-rich region (CRR) domain SPICA_RS07895 PF17764 3′ DNA-binding domain (3′BD) SPICA_RS07895 PF00271 Helicase conserved C-terminal domain SPICA_RS07910 PF01325 Iron dependent repressor, N-terminal DNA binding domain SPICA_RS07910 PF02742 Iron dependent repressor, metal binding and dimerisation domain SPICA_RS07915 PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase SPICA_RS07925 PF02277 Phosphoribosyltransferase SPICA_RS07930 PF02654 Cobalamin-5-phosphate synthase SPICA_RS07935 PF01189 16S rRNA methyltransferase RsmB/F SPICA_RS07935 PF13636 RNA-binding PUA-like domain of methyltransferase RsmF SPICA_RS07935 PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF SPICA_RS07940 PF00465 Iron-containing alcohol dehydrogenase SPICA_RS07945 PF00999 Sodium/hydrogen exchanger family SPICA_RS07945 PF03471 Transporter associated domain SPICA_RS07970 PF00872 Transposase, Mutator family SPICA_RS08005 PF04205 FMN-binding domain SPICA_RS08005 PF12801 4Fe-4S binding domain SPICA_RS08010 PF00633 Helix-hairpin-helix motif SPICA_RS08010 PF00730 HhH-GPD superfamily base excision DNA repair protein SPICA_RS08010 PF14815 NUDIX domain SPICA_RS08025 PF03755 YicC-like family, N-terminal region SPICA_RS08025 PF08340 Domain of unknown function (DUF1732) SPICA_RS08030 PF02875 Mur ligase family, glutamate ligase domain SPICA_RS08030 PF01225 Mur ligase family, catalytic domain SPICA_RS08030 PF08245 Mur ligase middle domain SPICA_RS08035 PF02875 Mur ligase family, glutamate ligase domain SPICA_RS08035 PF08245 Mur ligase middle domain SPICA_RS08040 PF07568 Histidine kinase SPICA_RS08040 PF12282 Signal transduction histidine kinase SPICA_RS08040 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS08045 PF00849 RNA pseudouridylate synthase SPICA_RS08045 PF01479 S4 domain SPICA_RS08050 PF00849 RNA pseudouridylate synthase SPICA_RS08060 PF01168 Alanine racemase, N-terminal domain SPICA_RS08065 PF00398 Ribosomal RNA adenine dimethylase SPICA_RS08090 PF00578 AhpC/TSA family SPICA_RS08095 PF02683 Cytochrome C biogenesis protein transmembrane region SPICA_RS08110 PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain SPICA_RS08110 PF17810 Arginine decarboxylase helical bundle domain SPICA_RS08110 PF17944 Arginine decarboxylase C-terminal helical extension SPICA_RS08115 PF00795 Carbon-nitrogen hydrolase SPICA_RS08120 PF04371 Porphyromonas-type peptidyl-arginine deiminase SPICA_RS08130 PF00180 Isocitrate/isopropylmalate dehydrogenase SPICA_RS08135 PF06971 Putative DNA-binding protein N-terminus SPICA_RS08135 PF02629 CoA binding domain SPICA_RS08140 PF10672 S-adenosylmethionine-dependent methyltransferase SPICA_RS08150 PF01197 Ribosomal protein L31 SPICA_RS08155 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPICA_RS08155 PF07498 Rho termination factor, N-terminal domain SPICA_RS08155 PF07497 Rho termination factor, RNA-binding domain SPICA_RS08160 PF00994 Probable molybdopterin binding domain SPICA_RS08160 PF02464 Competence-damaged protein SPICA_RS08160 PF18146 Damage-inducible protein CinA KH domain SPICA_RS08175 PF00486 Transcriptional regulatory protein, C terminal SPICA_RS08175 PF00072 Response regulator receiver domain SPICA_RS08180 PF00795 Carbon-nitrogen hydrolase SPICA_RS08185 PF00216 Bacterial DNA-binding protein SPICA_RS08190 PF01649 Ribosomal protein S20 SPICA_RS08195 PF02082 Transcriptional regulator SPICA_RS08205 PF13307 Helicase C-terminal domain SPICA_RS08205 PF06733 DEAD_2 SPICA_RS08220 PF01553 Acyltransferase SPICA_RS08225 PF17757 UvrB interaction domain SPICA_RS08225 PF03461 TRCF domain SPICA_RS08225 PF02559 CarD-like/TRCF domain SPICA_RS08225 PF00270 DEAD/DEAH box helicase SPICA_RS08225 PF00271 Helicase conserved C-terminal domain SPICA_RS08250 PF00521 DNA gyrase/topoisomerase IV, subunit A SPICA_RS08255 PF01751 Toprim domain SPICA_RS08255 PF00204 DNA gyrase B SPICA_RS08255 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS08255 PF00986 DNA gyrase B subunit, carboxyl terminus SPICA_RS08265 PF00679 Elongation factor G C-terminus SPICA_RS08265 PF14492 Elongation Factor G, domain II SPICA_RS08265 PF03764 Elongation factor G, domain IV SPICA_RS08265 PF00009 Elongation factor Tu GTP binding domain SPICA_RS08265 PF03144 Elongation factor Tu domain 2 SPICA_RS08270 PF00285 Citrate synthase, C-terminal domain SPICA_RS08275 PF01336 OB-fold nucleic acid binding domain SPICA_RS08275 PF00152 tRNA synthetases class II (D, K and N) SPICA_RS08280 PF07943 Penicillin-binding protein 5, C-terminal domain SPICA_RS08280 PF00768 D-alanyl-D-alanine carboxypeptidase SPICA_RS08285 PF04620 Flagellar filament outer layer protein Flaa SPICA_RS08295 PF01520 N-acetylmuramoyl-L-alanine amidase SPICA_RS08300 PF00206 Lyase SPICA_RS08300 PF02655 ATP-grasp domain SPICA_RS08310 PF02348 Cytidylyltransferase SPICA_RS08320 PF13186 Iron-sulfur cluster-binding domain SPICA_RS08325 PF13742 OB-fold nucleic acid binding domain SPICA_RS08325 PF02601 Exonuclease VII, large subunit SPICA_RS08330 PF02609 Exonuclease VII small subunit SPICA_RS08335 PF08676 MutL C terminal dimerisation domain SPICA_RS08335 PF01119 DNA mismatch repair protein, C-terminal domain SPICA_RS08355 PF01026 TatD related DNase SPICA_RS08370 PF18318 Glutamine synthetase C-terminal domain SPICA_RS08370 PF12437 Glutamine synthetase type III N terminal SPICA_RS08370 PF00120 Glutamine synthetase, catalytic domain SPICA_RS08380 PF00543 Nitrogen regulatory protein P-II SPICA_RS08385 PF00909 Ammonium Transporter Family SPICA_RS08390 PF00158 Sigma-54 interaction domain SPICA_RS08390 PF02954 Bacterial regulatory protein, Fis family SPICA_RS08390 PF01590 GAF domain SPICA_RS08395 PF13722 5TM C-terminal transporter carbon starvation CstA SPICA_RS08395 PF02554 Carbon starvation protein CstA SPICA_RS08405 PF02374 Anion-transporting ATPase SPICA_RS08425 PF00392 Bacterial regulatory proteins, gntR family SPICA_RS08430 PF02310 B12 binding domain SPICA_RS08435 PF13941 MutL protein SPICA_RS08440 PF06368 Methylaspartate mutase E chain (MutE) SPICA_RS08445 PF07476 Methylaspartate ammonia-lyase C-terminus SPICA_RS08445 PF05034 Methylaspartate ammonia-lyase N-terminus SPICA_RS08475 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SPICA_RS08475 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPICA_RS08475 PF03129 Anticodon binding domain SPICA_RS08485 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPICA_RS08485 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPICA_RS08485 PF18269 T3SS EscN ATPase C-terminal domain SPICA_RS08490 PF02108 Flagellar assembly protein FliH SPICA_RS08495 PF01706 FliG C-terminal domain SPICA_RS08495 PF14842 FliG N-terminal domain SPICA_RS08495 PF14841 FliG middle domain SPICA_RS08500 PF08345 Flagellar M-ring protein C-terminal SPICA_RS08500 PF01514 Secretory protein of YscJ/FliF family SPICA_RS08505 PF02049 Flagellar hook-basal body complex protein FliE SPICA_RS08510 PF00460 Flagella basal body rod protein SPICA_RS08510 PF06429 Flagellar basal body rod FlgEFG protein C-terminal SPICA_RS08515 PF00460 Flagella basal body rod protein SPICA_RS08520 PF07724 AAA domain (Cdc48 subfamily) SPICA_RS08520 PF00004 ATPase family associated with various cellular activities (AAA) SPICA_RS08525 PF00227 Proteasome subunit SPICA_RS08530 PF00589 Phage integrase family SPICA_RS08530 PF02899 Phage integrase, N-terminal SAM-like domain SPICA_RS08535 PF01396 Topoisomerase DNA binding C4 zinc finger SPICA_RS08535 PF01131 DNA topoisomerase SPICA_RS08535 PF01751 Toprim domain SPICA_RS08540 PF02481 DNA recombination-mediator protein A SPICA_RS08540 PF17782 DprA winged helix domain SPICA_RS08550 PF02899 Phage integrase, N-terminal SAM-like domain SPICA_RS08550 PF00589 Phage integrase family SPICA_RS08555 PF12327 FtsZ family, C-terminal domain SPICA_RS08555 PF00091 Tubulin/FtsZ family, GTPase domain SPICA_RS08560 PF02491 SHS2 domain inserted in FTSA SPICA_RS08570 PF01098 Cell cycle protein SPICA_RS08575 PF00953 Glycosyl transferase family 4 SPICA_RS08575 PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 SPICA_RS08580 PF08245 Mur ligase middle domain SPICA_RS08580 PF02875 Mur ligase family, glutamate ligase domain SPICA_RS08580 PF01225 Mur ligase family, catalytic domain SPICA_RS08590 PF01795 MraW methylase family SPICA_RS08595 PF02381 MraZ protein, putative antitoxin-like SPICA_RS08625 PF01116 Fructose-bisphosphate aldolase class-II SPICA_RS08635 PF00707 Translation initiation factor IF-3, C-terminal domain SPICA_RS08635 PF05198 Translation initiation factor IF-3, N-terminal domain SPICA_RS08640 PF01632 Ribosomal protein L35 SPICA_RS08645 PF00453 Ribosomal protein L20 SPICA_RS08655 PF05164 Cell division protein ZapA SPICA_RS08660 PF01238 Phosphomannose isomerase type I SPICA_RS08665 PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 SPICA_RS08670 PF11849 Domain of unknown function (DUF3369) SPICA_RS08675 PF05698 Bacterial trigger factor protein (TF) C-terminus SPICA_RS08685 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPICA_RS08685 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPICA_RS08690 PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) SPICA_RS08690 PF02817 e3 binding domain SPICA_RS08690 PF00364 Biotin-requiring enzyme SPICA_RS08695 PF02780 Transketolase, C-terminal domain SPICA_RS08695 PF02779 Transketolase, pyrimidine binding domain SPICA_RS08695 PF00364 Biotin-requiring enzyme SPICA_RS08700 PF00676 Dehydrogenase E1 component SPICA_RS08710 PF00005 ABC transporter SPICA_RS08715 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS08720 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS08725 PF12849 PBP superfamily domain SPICA_RS08750 PF01593 Flavin containing amine oxidoreductase SPICA_RS08760 PF00970 Oxidoreductase FAD-binding domain SPICA_RS08760 PF00111 2Fe-2S iron-sulfur cluster binding domain SPICA_RS08760 PF00175 Oxidoreductase NAD-binding domain SPICA_RS08765 PF02508 Rnf-Nqr subunit, membrane protein SPICA_RS08770 PF02508 Rnf-Nqr subunit, membrane protein SPICA_RS08775 PF04205 FMN-binding domain SPICA_RS08780 PF03116 NQR2, RnfD, RnfE family SPICA_RS08785 PF03099 Biotin/lipoate A/B protein ligase family SPICA_RS08795 PF04055 Radical SAM superfamily SPICA_RS08795 PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family SPICA_RS08800 PF00589 Phage integrase family SPICA_RS08800 PF13495 Phage integrase, N-terminal SAM-like domain SPICA_RS08805 PF04471 Restriction endonuclease SPICA_RS08805 PF14338 Mrr N-terminal domain SPICA_RS08910 PF04471 Restriction endonuclease SPICA_RS08910 PF14338 Mrr N-terminal domain SPICA_RS08935 PF04471 Restriction endonuclease SPICA_RS08935 PF14338 Mrr N-terminal domain SPICA_RS09050 PF00300 Histidine phosphatase superfamily (branch 1) SPICA_RS09115 PF00872 Transposase, Mutator family SPICA_RS09120 PF13180 PDZ domain SPICA_RS09120 PF17820 PDZ domain SPICA_RS09160 PF02463 RecF/RecN/SMC N terminal domain SPICA_RS09165 PF01513 ATP-NAD kinase SPICA_RS09170 PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family SPICA_RS09175 PF01584 CheW-like domain SPICA_RS09210 PF00595 PDZ domain SPICA_RS09215 PF00557 Metallopeptidase family M24 SPICA_RS09220 PF00226 DnaJ domain SPICA_RS09220 PF00684 DnaJ central domain SPICA_RS09220 PF01556 DnaJ C terminal domain SPICA_RS09235 PF01813 ATP synthase subunit D SPICA_RS09240 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPICA_RS09240 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPICA_RS09245 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPICA_RS09245 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPICA_RS09245 PF16886 ATPsynthase alpha/beta subunit N-term extension SPICA_RS09265 PF01496 V-type ATPase 116kDa subunit family SPICA_RS09280 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPICA_RS09285 PF03840 Preprotein translocase SecG subunit SPICA_RS09290 PF00121 Triosephosphate isomerase SPICA_RS09295 PF00162 Phosphoglycerate kinase SPICA_RS09300 PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain SPICA_RS09300 PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain SPICA_RS09310 PF08264 Anticodon-binding domain of tRNA SPICA_RS09310 PF00133 tRNA synthetases class I (I, L, M and V) SPICA_RS09310 PF10458 Valyl tRNA synthetase tRNA binding arm SPICA_RS09315 PF02401 LytB protein SPICA_RS09320 PF02355 Protein export membrane protein SPICA_RS09325 PF02355 Protein export membrane protein SPICA_RS09330 PF02699 Preprotein translocase subunit SPICA_RS09340 PF00301 Rubredoxin SPICA_RS09345 PF01880 Desulfoferrodoxin SPICA_RS09345 PF06397 Desulfoferrodoxin, N-terminal domain SPICA_RS09350 PF02915 Rubrerythrin SPICA_RS09380 PF01343 Peptidase family S49 SPICA_RS09390 PF17871 AAA lid domain SPICA_RS09390 PF07724 AAA domain (Cdc48 subfamily) SPICA_RS09390 PF00004 ATPase family associated with various cellular activities (AAA) SPICA_RS09390 PF02861 Clp amino terminal domain, pathogenicity island component SPICA_RS09390 PF10431 C-terminal, D2-small domain, of ClpB protein SPICA_RS09395 PF02872 5'-nucleotidase, C-terminal domain SPICA_RS09395 PF00149 Calcineurin-like phosphoesterase SPICA_RS09405 PF02540 NAD synthase SPICA_RS09405 PF00117 Glutamine amidotransferase class-I SPICA_RS09405 PF00958 GMP synthase C terminal domain SPICA_RS09410 PF00709 Adenylosuccinate synthetase SPICA_RS09415 PF00478 IMP dehydrogenase / GMP reductase domain SPICA_RS09415 PF00571 CBS domain SPICA_RS09420 PF10397 Adenylosuccinate lyase C-terminus SPICA_RS09420 PF00206 Lyase SPICA_RS09455 PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster SPICA_RS09455 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPICA_RS09460 PF01493 GXGXG motif SPICA_RS09460 PF01645 Conserved region in glutamate synthase SPICA_RS09460 PF04898 Glutamate synthase central domain SPICA_RS09460 PF00310 Glutamine amidotransferases class-II SPICA_RS09470 PF00672 HAMP domain SPICA_RS09470 PF02743 Cache domain SPICA_RS09470 PF06580 Histidine kinase SPICA_RS09470 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS09475 PF12833 Helix-turn-helix domain SPICA_RS09475 PF00072 Response regulator receiver domain SPICA_RS09480 PF13407 Periplasmic binding protein domain SPICA_RS09485 PF13407 Periplasmic binding protein domain SPICA_RS09490 PF00005 ABC transporter SPICA_RS09495 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS09500 PF07687 Peptidase dimerisation domain SPICA_RS09500 PF01546 Peptidase family M20/M25/M40 SPICA_RS09525 PF01926 50S ribosome-binding GTPase SPICA_RS09525 PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SPICA_RS09530 PF10415 Fumarase C C-terminus SPICA_RS09530 PF00206 Lyase SPICA_RS09535 PF06968 Biotin and Thiamin Synthesis associated domain SPICA_RS09535 PF04055 Radical SAM superfamily SPICA_RS09540 PF06968 Biotin and Thiamin Synthesis associated domain SPICA_RS09540 PF04055 Radical SAM superfamily SPICA_RS09575 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPICA_RS09575 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPICA_RS09580 PF01262 Alanine dehydrogenase/PNT, C-terminal domain SPICA_RS09580 PF05222 Alanine dehydrogenase/PNT, N-terminal domain SPICA_RS09590 PF07690 Major Facilitator Superfamily SPICA_RS09590 PF00083 Sugar (and other) transporter SPICA_RS09600 PF00149 Calcineurin-like phosphoesterase SPICA_RS09600 PF12320 Type 5 capsule protein repressor C-terminal domain SPICA_RS09605 PF13476 AAA domain SPICA_RS09615 PF00857 Isochorismatase family SPICA_RS09620 PF17767 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain SPICA_RS09620 PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family SPICA_RS09620 PF17956 Nicotinate phosphoribosyltransferase C-terminal domain SPICA_RS09630 PF13416 Bacterial extracellular solute-binding protein SPICA_RS09635 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS09640 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS09655 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPICA_RS09660 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS09665 PF01171 PP-loop family SPICA_RS09695 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS09700 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS09705 PF01547 Bacterial extracellular solute-binding protein SPICA_RS09710 PF00392 Bacterial regulatory proteins, gntR family SPICA_RS09710 PF07702 UTRA domain SPICA_RS09715 PF03797 Autotransporter beta-domain SPICA_RS09715 PF00082 Subtilase family SPICA_RS09715 PF12951 Passenger-associated-transport-repeat SPICA_RS09725 PF02929 Beta galactosidase small chain SPICA_RS09725 PF16353 Domain of unknown function(DUF4981) SPICA_RS09725 PF00703 Glycosyl hydrolases family 2 SPICA_RS09725 PF02836 Glycosyl hydrolases family 2, TIM barrel domain SPICA_RS09725 PF02837 Glycosyl hydrolases family 2, sugar binding domain SPICA_RS09730 PF00392 Bacterial regulatory proteins, gntR family SPICA_RS09750 PF02146 Sir2 family SPICA_RS09780 PF09827 CRISPR associated protein Cas2 SPICA_RS09785 PF01867 CRISPR associated protein Cas1 SPICA_RS09805 PF09704 CRISPR-associated protein (Cas_Cas5) SPICA_RS09815 PF00579 tRNA synthetases class I (W and Y) SPICA_RS09840 PF01625 Peptide methionine sulfoxide reductase SPICA_RS09840 PF01641 SelR domain SPICA_RS09845 PF02151 UvrB/uvrC motif SPICA_RS09845 PF17757 UvrB interaction domain SPICA_RS09845 PF12344 Ultra-violet resistance protein B SPICA_RS09845 PF00271 Helicase conserved C-terminal domain SPICA_RS09845 PF04851 Type III restriction enzyme, res subunit SPICA_RS09850 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS09850 PF00672 HAMP domain SPICA_RS09850 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS09860 PF03099 Biotin/lipoate A/B protein ligase family SPICA_RS09860 PF12706 Beta-lactamase superfamily domain SPICA_RS09865 PF00830 Ribosomal L28 family SPICA_RS09880 PF01053 Cys/Met metabolism PLP-dependent enzyme SPICA_RS09885 PF02743 Cache domain SPICA_RS09885 PF00672 HAMP domain SPICA_RS09885 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS09895 PF00004 ATPase family associated with various cellular activities (AAA) SPICA_RS09895 PF02190 ATP-dependent protease La (LON) substrate-binding domain SPICA_RS09895 PF05362 Lon protease (S16) C-terminal proteolytic domain SPICA_RS09930 PF00271 Helicase conserved C-terminal domain SPICA_RS09930 PF00570 HRDC domain SPICA_RS09930 PF16124 RecQ zinc-binding SPICA_RS09930 PF00270 DEAD/DEAH box helicase SPICA_RS09930 PF09382 RQC domain SPICA_RS09935 PF00270 DEAD/DEAH box helicase SPICA_RS09935 PF00271 Helicase conserved C-terminal domain SPICA_RS09945 PF01180 Dihydroorotate dehydrogenase SPICA_RS09950 PF14841 FliG middle domain SPICA_RS09950 PF14842 FliG N-terminal domain SPICA_RS09950 PF01706 FliG C-terminal domain SPICA_RS09955 PF08367 Peptidase M16C associated SPICA_RS09955 PF00675 Insulinase (Peptidase family M16) SPICA_RS09955 PF05193 Peptidase M16 inactive domain SPICA_RS09965 PF17191 RecG wedge domain SPICA_RS09965 PF00271 Helicase conserved C-terminal domain SPICA_RS09965 PF00270 DEAD/DEAH box helicase SPICA_RS09975 PF00072 Response regulator receiver domain SPICA_RS09975 PF00990 Diguanylate cyclase, GGDEF domain SPICA_RS09980 PF17657 Bacterial DNA polymerase III alpha subunit finger domain SPICA_RS09980 PF07733 Bacterial DNA polymerase III alpha NTPase domain SPICA_RS09980 PF02811 PHP domain SPICA_RS09980 PF14579 Helix-hairpin-helix motif SPICA_RS09985 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS09990 PF00155 Aminotransferase class I and II SPICA_RS10000 PF01165 Ribosomal protein S21 SPICA_RS10010 PF01368 DHH family SPICA_RS10010 PF02272 DHHA1 domain SPICA_RS10010 PF17768 RecJ OB domain SPICA_RS10010 PF10141 Single-strand DNA-specific exonuclease, C terminal domain SPICA_RS10015 PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain SPICA_RS10015 PF00591 Glycosyl transferase family, a/b domain SPICA_RS10015 PF02885 Glycosyl transferase family, helical bundle domain SPICA_RS10025 PF00583 Acetyltransferase (GNAT) family SPICA_RS10025 PF00696 Amino acid kinase family SPICA_RS10030 PF02867 Ribonucleotide reductase, barrel domain SPICA_RS10030 PF08471 Class II vitamin B12-dependent ribonucleotide reductase SPICA_RS10045 PF02535 ZIP Zinc transporter SPICA_RS10050 PF05191 Adenylate kinase, active site lid SPICA_RS10055 PF01207 Dihydrouridine synthase (Dus) SPICA_RS10060 PF08220 DeoR-like helix-turn-helix domain SPICA_RS10060 PF00455 DeoR C terminal sensor domain SPICA_RS10065 PF00364 Biotin-requiring enzyme SPICA_RS10065 PF02817 e3 binding domain SPICA_RS10065 PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) SPICA_RS10070 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPICA_RS10070 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPICA_RS10075 PF02779 Transketolase, pyrimidine binding domain SPICA_RS10075 PF02780 Transketolase, C-terminal domain SPICA_RS10095 PF08240 Alcohol dehydrogenase GroES-like domain SPICA_RS10095 PF00107 Zinc-binding dehydrogenase SPICA_RS10110 PF00704 Glycosyl hydrolases family 18 SPICA_RS10120 PF13173 AAA domain SPICA_RS10120 PF13635 Domain of unknown function (DUF4143) SPICA_RS10155 PF02687 FtsX-like permease family SPICA_RS10155 PF12704 MacB-like periplasmic core domain SPICA_RS10160 PF12704 MacB-like periplasmic core domain SPICA_RS10160 PF00005 ABC transporter SPICA_RS10160 PF02687 FtsX-like permease family SPICA_RS10165 PF00005 ABC transporter SPICA_RS10175 PF16736 Single Cache-like SPICA_RS10175 PF00989 PAS fold SPICA_RS10175 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS10175 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS10180 PF00072 Response regulator receiver domain SPICA_RS10180 PF00486 Transcriptional regulatory protein, C terminal SPICA_RS10190 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS10195 PF00005 ABC transporter SPICA_RS10200 PF13407 Periplasmic binding protein domain SPICA_RS10205 PF13407 Periplasmic binding protein domain SPICA_RS10210 PF00196 Bacterial regulatory proteins, luxR family SPICA_RS10210 PF00072 Response regulator receiver domain SPICA_RS10215 PF00672 HAMP domain SPICA_RS10215 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS10215 PF06580 Histidine kinase SPICA_RS10215 PF02743 Cache domain SPICA_RS10225 PF03588 Leucyl/phenylalanyl-tRNA protein transferase SPICA_RS10230 PF07724 AAA domain (Cdc48 subfamily) SPICA_RS10230 PF02861 Clp amino terminal domain, pathogenicity island component SPICA_RS10230 PF10431 C-terminal, D2-small domain, of ClpB protein SPICA_RS10230 PF00004 ATPase family associated with various cellular activities (AAA) SPICA_RS10230 PF17871 AAA lid domain SPICA_RS10235 PF02617 ATP-dependent Clp protease adaptor protein ClpS SPICA_RS10245 PF03372 Endonuclease/Exonuclease/phosphatase family SPICA_RS10260 PF06964 Alpha-L-arabinofuranosidase C-terminal domain SPICA_RS10265 PF00873 AcrB/AcrD/AcrF family SPICA_RS10270 PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion SPICA_RS10280 PF00575 S1 RNA binding domain SPICA_RS10290 PF13185 GAF domain SPICA_RS10295 PF01594 AI-2E family transporter SPICA_RS10305 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS10310 PF12911 N-terminal TM domain of oligopeptide transport permease C SPICA_RS10310 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS10315 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SPICA_RS10315 PF00005 ABC transporter SPICA_RS10320 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SPICA_RS10320 PF00005 ABC transporter SPICA_RS10325 PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SPICA_RS10325 PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SPICA_RS10330 PF00698 Acyl transferase domain SPICA_RS10340 PF02801 Beta-ketoacyl synthase, C-terminal domain SPICA_RS10340 PF00109 Beta-ketoacyl synthase, N-terminal domain SPICA_RS10345 PF07977 FabA-like domain SPICA_RS10350 PF12241 Trans-2-enoyl-CoA reductase catalytic region SPICA_RS10350 PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SPICA_RS10350 PF07055 Enoyl reductase FAD binding domain SPICA_RS10355 PF00364 Biotin-requiring enzyme SPICA_RS10360 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SPICA_RS10360 PF02785 Biotin carboxylase C-terminal domain SPICA_RS10360 PF00289 Biotin carboxylase, N-terminal domain SPICA_RS10365 PF01039 Carboxyl transferase domain SPICA_RS10370 PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SPICA_RS10380 PF01545 Cation efflux family SPICA_RS10380 PF16916 Dimerisation domain of Zinc Transporter SPICA_RS10390 PF01380 SIS domain SPICA_RS10400 PF00436 Single-strand binding protein family SPICA_RS10405 PF01136 Peptidase family U32 SPICA_RS10405 PF16325 Peptidase family U32 C-terminal domain SPICA_RS10410 PF01914 MarC family integral membrane protein SPICA_RS10415 PF00085 Thioredoxin SPICA_RS10430 PF03099 Biotin/lipoate A/B protein ligase family SPICA_RS10430 PF10437 Bacterial lipoate protein ligase C-terminus SPICA_RS10475 PF01202 Shikimate kinase SPICA_RS10480 PF00563 EAL domain SPICA_RS10480 PF00990 Diguanylate cyclase, GGDEF domain SPICA_RS10480 PF08448 PAS fold SPICA_RS10490 PF00365 Phosphofructokinase SPICA_RS10500 PF01055 Glycosyl hydrolases family 31 SPICA_RS10520 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS10525 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS10540 PF00480 ROK family SPICA_RS10545 PF00899 ThiF family SPICA_RS10560 PF02463 RecF/RecN/SMC N terminal domain SPICA_RS10585 PF12137 RNA polymerase recycling family C-terminal SPICA_RS10585 PF00176 SNF2 family N-terminal domain SPICA_RS10585 PF18337 RapA N-terminal Tudor like domain SPICA_RS10585 PF00271 Helicase conserved C-terminal domain SPICA_RS10585 PF18339 RapA N-terminal Tudor like domain 1 SPICA_RS10600 PF00456 Transketolase, thiamine diphosphate binding domain SPICA_RS10605 PF02779 Transketolase, pyrimidine binding domain SPICA_RS10605 PF02780 Transketolase, C-terminal domain SPICA_RS10610 PF02502 Ribose/Galactose Isomerase SPICA_RS10615 PF00465 Iron-containing alcohol dehydrogenase SPICA_RS10630 PF00291 Pyridoxal-phosphate dependent enzyme SPICA_RS10635 PF01569 PAP2 superfamily SPICA_RS10645 PF00483 Nucleotidyl transferase SPICA_RS10655 PF10396 GTP-binding protein TrmE N-terminus SPICA_RS10655 PF01926 50S ribosome-binding GTPase SPICA_RS10655 PF12631 MnmE helical domain SPICA_RS10660 PF13932 GidA associated domain SPICA_RS10660 PF01134 Glucose inhibited division protein A SPICA_RS10665 PF00462 Glutaredoxin SPICA_RS10700 PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SPICA_RS10700 PF02542 YgbB family SPICA_RS10705 PF02542 YgbB family SPICA_RS10710 PF00633 Helix-hairpin-helix motif SPICA_RS10710 PF00730 HhH-GPD superfamily base excision DNA repair protein SPICA_RS10710 PF10576 Iron-sulfur binding domain of endonuclease III SPICA_RS10720 PF13419 Haloacid dehalogenase-like hydrolase SPICA_RS10730 PF02472 Biopolymer transport protein ExbD/TolR SPICA_RS10735 PF01618 MotA/TolQ/ExbB proton channel family SPICA_RS10755 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS10760 PF00128 Alpha amylase, catalytic domain SPICA_RS10765 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS10770 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS10780 PF00872 Transposase, Mutator family SPICA_RS10785 PF10388 EAL-domain associated signalling protein domain SPICA_RS10785 PF00563 EAL domain SPICA_RS10790 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS10790 PF12729 Four helix bundle sensory module for signal transduction SPICA_RS10790 PF00672 HAMP domain SPICA_RS10795 PF03193 RsgA GTPase SPICA_RS10800 PF00072 Response regulator receiver domain SPICA_RS10800 PF00196 Bacterial regulatory proteins, luxR family SPICA_RS10810 PF00005 ABC transporter SPICA_RS10825 PF07690 Major Facilitator Superfamily SPICA_RS10835 PF02096 60Kd inner membrane protein SPICA_RS10845 PF08402 TOBE domain SPICA_RS10845 PF00005 ABC transporter SPICA_RS10850 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS10855 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS10860 PF13416 Bacterial extracellular solute-binding protein SPICA_RS10865 PF01300 Telomere recombination SPICA_RS10870 PF03600 Citrate transporter SPICA_RS10875 PF00072 Response regulator receiver domain SPICA_RS10875 PF02954 Bacterial regulatory protein, Fis family SPICA_RS10875 PF00158 Sigma-54 interaction domain SPICA_RS10880 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS10880 PF00672 HAMP domain SPICA_RS10880 PF02743 Cache domain SPICA_RS10880 PF06580 Histidine kinase SPICA_RS10885 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS10890 PF00005 ABC transporter SPICA_RS10895 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS10900 PF13407 Periplasmic binding protein domain SPICA_RS10905 PF01297 Zinc-uptake complex component A periplasmic SPICA_RS10910 PF00005 ABC transporter SPICA_RS10915 PF00950 ABC 3 transport family SPICA_RS10925 PF17746 SfsA N-terminal OB domain SPICA_RS10925 PF03749 Sugar fermentation stimulation protein RE domain SPICA_RS10930 PF00892 EamA-like transporter family SPICA_RS10940 PF05016 ParE toxin of type II toxin-antitoxin system, parDE SPICA_RS10960 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPICA_RS10960 PF03466 LysR substrate binding domain SPICA_RS10965 PF03601 Conserved hypothetical protein 698 SPICA_RS10970 PF07690 Major Facilitator Superfamily SPICA_RS10980 PF01566 Natural resistance-associated macrophage protein SPICA_RS10990 PF00689 Cation transporting ATPase, C-terminus SPICA_RS10990 PF00690 Cation transporter/ATPase, N-terminus SPICA_RS10995 PF01042 Endoribonuclease L-PSP SPICA_RS11045 PF01975 Survival protein SurE SPICA_RS11060 PF00665 Integrase core domain SPICA_RS11060 PF13276 HTH-like domain SPICA_RS11060 PF13333 Integrase core domain SPICA_RS11075 PF00005 ABC transporter SPICA_RS11075 PF00664 ABC transporter transmembrane region SPICA_RS11075 PF03412 Peptidase C39 family SPICA_RS11185 PF00534 Glycosyl transferases group 1 SPICA_RS11185 PF13439 Glycosyltransferase Family 4 SPICA_RS11230 PF06580 Histidine kinase SPICA_RS11230 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS11230 PF00672 HAMP domain SPICA_RS11230 PF02743 Cache domain SPICA_RS11235 PF00072 Response regulator receiver domain SPICA_RS11235 PF12833 Helix-turn-helix domain SPICA_RS11240 PF13407 Periplasmic binding protein domain SPICA_RS11245 PF13407 Periplasmic binding protein domain SPICA_RS11250 PF00005 ABC transporter SPICA_RS11255 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS11260 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS11265 PF16874 Glycosyl hydrolase family 36 C-terminal domain SPICA_RS11265 PF16875 Glycosyl hydrolase family 36 N-terminal domain SPICA_RS11275 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS11280 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS11285 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS11295 PF01139 tRNA-splicing ligase RtcB SPICA_RS11305 PF04434 SWIM zinc finger SPICA_RS11305 PF00176 SNF2 family N-terminal domain SPICA_RS11305 PF00271 Helicase conserved C-terminal domain SPICA_RS11335 PF00850 Histone deacetylase domain SPICA_RS11360 PF00005 ABC transporter SPICA_RS11365 PF01145 SPFH domain / Band 7 family SPICA_RS11370 PF00392 Bacterial regulatory proteins, gntR family SPICA_RS11375 PF07882 L-fucose isomerase, second N-terminal domain SPICA_RS11375 PF07881 L-fucose isomerase, first N-terminal domain SPICA_RS11375 PF02952 L-fucose isomerase, C-terminal domain SPICA_RS11380 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS11390 PF05025 RbsD / FucU transport protein family SPICA_RS11400 PF08240 Alcohol dehydrogenase GroES-like domain SPICA_RS11400 PF00107 Zinc-binding dehydrogenase SPICA_RS11405 PF00294 pfkB family carbohydrate kinase SPICA_RS11410 PF00381 PTS HPr component phosphorylation site SPICA_RS11415 PF05524 PEP-utilising enzyme, N-terminal SPICA_RS11415 PF02896 PEP-utilising enzyme, TIM barrel domain SPICA_RS11415 PF00391 PEP-utilising enzyme, mobile domain SPICA_RS11420 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPICA_RS11425 PF05043 Mga helix-turn-helix domain SPICA_RS11425 PF00874 PRD domain SPICA_RS11425 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPICA_RS11425 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPICA_RS11425 PF08279 HTH domain SPICA_RS11430 PF02378 Phosphotransferase system, EIIC SPICA_RS11430 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPICA_RS11440 PF02811 PHP domain SPICA_RS11445 PF01554 MatE SPICA_RS11450 PF00294 pfkB family carbohydrate kinase SPICA_RS11455 PF00484 Carbonic anhydrase SPICA_RS11470 PF02522 Aminoglycoside 3-N-acetyltransferase SPICA_RS11475 PF00403 Heavy-metal-associated domain SPICA_RS11480 PF01022 Bacterial regulatory protein, arsR family SPICA_RS11495 PF00293 NUDIX domain SPICA_RS11520 PF01740 STAS domain SPICA_RS11520 PF00916 Sulfate permease family SPICA_RS11535 PF00664 ABC transporter transmembrane region SPICA_RS11535 PF00005 ABC transporter SPICA_RS11545 PF00664 ABC transporter transmembrane region SPICA_RS11545 PF00005 ABC transporter SPICA_RS11590 PF00672 HAMP domain SPICA_RS11590 PF07730 Histidine kinase SPICA_RS11590 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS11595 PF00072 Response regulator receiver domain SPICA_RS11595 PF00196 Bacterial regulatory proteins, luxR family SPICA_RS11600 PF01547 Bacterial extracellular solute-binding protein SPICA_RS11605 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS11610 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS11620 PF01812 5-formyltetrahydrofolate cyclo-ligase family SPICA_RS11640 PF08534 Redoxin SPICA_RS11660 PF04616 Glycosyl hydrolases family 43 SPICA_RS11665 PF00135 Carboxylesterase family SPICA_RS11705 PF07690 Major Facilitator Superfamily SPICA_RS11710 PF03186 CobD/Cbib protein SPICA_RS11715 PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain SPICA_RS11715 PF00155 Aminotransferase class I and II SPICA_RS11715 PF07685 CobB/CobQ-like glutamine amidotransferase domain SPICA_RS11720 PF01264 Chorismate synthase SPICA_RS11725 PF17863 AAA lid domain SPICA_RS11725 PF07726 ATPase family associated with various cellular activities (AAA) SPICA_RS11755 PF07726 ATPase family associated with various cellular activities (AAA) SPICA_RS11755 PF17863 AAA lid domain SPICA_RS11760 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS11765 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS11770 PF00005 ABC transporter SPICA_RS11775 PF13407 Periplasmic binding protein domain SPICA_RS11780 PF13407 Periplasmic binding protein domain SPICA_RS11785 PF06580 Histidine kinase SPICA_RS11785 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS11785 PF02743 Cache domain SPICA_RS11785 PF00672 HAMP domain SPICA_RS11790 PF00072 Response regulator receiver domain SPICA_RS11790 PF12833 Helix-turn-helix domain SPICA_RS11795 PF13193 AMP-binding enzyme C-terminal domain SPICA_RS11795 PF00501 AMP-binding enzyme SPICA_RS11810 PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) SPICA_RS11820 PF08501 Shikimate dehydrogenase substrate binding domain SPICA_RS11820 PF01488 Shikimate / quinate 5-dehydrogenase SPICA_RS11830 PF00501 AMP-binding enzyme SPICA_RS11840 PF03793 PASTA domain SPICA_RS11845 PF02911 Formyl transferase, C-terminal domain SPICA_RS11845 PF00551 Formyl transferase SPICA_RS11850 PF01327 Polypeptide deformylase SPICA_RS11855 PF00912 Transglycosylase SPICA_RS11855 PF00905 Penicillin binding protein transpeptidase domain SPICA_RS11855 PF06832 Penicillin-Binding Protein C-terminus Family SPICA_RS11860 PF17962 Bacterial macroglobulin domain 6 SPICA_RS11860 PF11974 Bacterial alpha-2-macroglobulin MG3 domain SPICA_RS11860 PF17973 Bacterial Alpha-2-macroglobulin MG10 domain SPICA_RS11860 PF01835 MG2 domain SPICA_RS11860 PF17972 Bacterial Alpha-2-macroglobulin MG5 domain SPICA_RS11860 PF07703 Alpha-2-macroglobulin bait region domain SPICA_RS11860 PF00207 Alpha-2-macroglobulin family SPICA_RS11865 PF01590 GAF domain SPICA_RS11865 PF00990 Diguanylate cyclase, GGDEF domain SPICA_RS11865 PF00563 EAL domain SPICA_RS11865 PF00360 Phytochrome region SPICA_RS11870 PF01339 CheB methylesterase SPICA_RS11870 PF00072 Response regulator receiver domain SPICA_RS11875 PF03975 CheD chemotactic sensory transduction SPICA_RS11880 PF03705 CheR methyltransferase, all-alpha domain SPICA_RS11880 PF01739 CheR methyltransferase, SAM binding domain SPICA_RS11885 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS11885 PF02203 Tar ligand binding domain homologue SPICA_RS11885 PF00672 HAMP domain SPICA_RS11890 PF01584 CheW-like domain SPICA_RS11895 PF00072 Response regulator receiver domain SPICA_RS11895 PF00486 Transcriptional regulatory protein, C terminal SPICA_RS11900 PF01584 CheW-like domain SPICA_RS11900 PF02895 Signal transducing histidine kinase, homodimeric domain SPICA_RS11900 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS11900 PF07194 P2 response regulator binding domain SPICA_RS11900 PF01627 Hpt domain SPICA_RS11910 PF00072 Response regulator receiver domain SPICA_RS11910 PF00486 Transcriptional regulatory protein, C terminal SPICA_RS11915 PF08240 Alcohol dehydrogenase GroES-like domain SPICA_RS11915 PF00107 Zinc-binding dehydrogenase SPICA_RS11920 PF00248 Aldo/keto reductase family SPICA_RS11925 PF00532 Periplasmic binding proteins and sugar binding domain of LacI family SPICA_RS11925 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS11930 PF16338 Domain of unknown function (DUF4968) SPICA_RS11930 PF17137 Domain of unknown function (DUF5110) SPICA_RS11930 PF01055 Glycosyl hydrolases family 31 SPICA_RS11935 PF00488 MutS domain V SPICA_RS11935 PF05190 MutS family domain IV SPICA_RS11935 PF05192 MutS domain III SPICA_RS11935 PF01624 MutS domain I SPICA_RS11935 PF05188 MutS domain II SPICA_RS11940 PF01713 Smr domain SPICA_RS11940 PF00488 MutS domain V SPICA_RS11965 PF08669 Glycine cleavage T-protein C-terminal barrel domain SPICA_RS11965 PF01571 Aminomethyltransferase folate-binding domain SPICA_RS11970 PF01597 Glycine cleavage H-protein SPICA_RS11975 PF02347 Glycine cleavage system P-protein SPICA_RS11980 PF02347 Glycine cleavage system P-protein SPICA_RS11995 PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain SPICA_RS11995 PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain SPICA_RS12005 PF13649 Methyltransferase domain SPICA_RS12010 PF01050 Mannose-6-phosphate isomerase SPICA_RS12010 PF00483 Nucleotidyl transferase SPICA_RS12015 PF00871 Acetokinase family SPICA_RS12020 PF00294 pfkB family carbohydrate kinase SPICA_RS12025 PF01965 DJ-1/PfpI family SPICA_RS12030 PF00486 Transcriptional regulatory protein, C terminal SPICA_RS12030 PF00072 Response regulator receiver domain SPICA_RS12035 PF01627 Hpt domain SPICA_RS12035 PF00072 Response regulator receiver domain SPICA_RS12035 PF09984 Uncharacterised signal transduction histidine kinase domain (DUF2222) SPICA_RS12035 PF00672 HAMP domain SPICA_RS12035 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS12035 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS12040 PF02811 PHP domain SPICA_RS12050 PF01176 Translation initiation factor 1A / IF-1 SPICA_RS12055 PF01713 Smr domain SPICA_RS12085 PF01882 Protein of unknown function DUF58 SPICA_RS12090 PF07726 ATPase family associated with various cellular activities (AAA) SPICA_RS12090 PF17863 AAA lid domain SPICA_RS12115 PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain SPICA_RS12115 PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain SPICA_RS12130 PF06071 Protein of unknown function (DUF933) SPICA_RS12130 PF01926 50S ribosome-binding GTPase SPICA_RS12140 PF01063 Amino-transferase class IV SPICA_RS12150 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPICA_RS12150 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SPICA_RS12150 PF03129 Anticodon binding domain SPICA_RS12170 PF18072 Formylglycinamide ribonucleotide amidotransferase linker domain SPICA_RS12170 PF02769 AIR synthase related protein, C-terminal domain SPICA_RS12170 PF00586 AIR synthase related protein, N-terminal domain SPICA_RS12185 PF02540 NAD synthase SPICA_RS12185 PF00795 Carbon-nitrogen hydrolase SPICA_RS12205 PF16921 Tex protein YqgF-like domain SPICA_RS12205 PF09371 Tex-like protein N-terminal domain SPICA_RS12205 PF00575 S1 RNA binding domain SPICA_RS12205 PF17674 HHH domain SPICA_RS12210 PF02527 rRNA small subunit methyltransferase G SPICA_RS12220 PF17202 Single cache domain 3 SPICA_RS12220 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS12220 PF00672 HAMP domain SPICA_RS12225 PF07470 Glycosyl Hydrolase Family 88 SPICA_RS12230 PF03306 Alpha-acetolactate decarboxylase SPICA_RS12240 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS12240 PF00672 HAMP domain SPICA_RS12240 PF12729 Four helix bundle sensory module for signal transduction SPICA_RS12245 PF01259 SAICAR synthetase SPICA_RS12250 PF00156 Phosphoribosyl transferase domain SPICA_RS12255 PF02769 AIR synthase related protein, C-terminal domain SPICA_RS12255 PF00586 AIR synthase related protein, N-terminal domain SPICA_RS12260 PF00551 Formyl transferase SPICA_RS12265 PF01808 AICARFT/IMPCHase bienzyme SPICA_RS12265 PF02142 MGS-like domain SPICA_RS12270 PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SPICA_RS12270 PF02844 Phosphoribosylglycinamide synthetase, N domain SPICA_RS12270 PF02843 Phosphoribosylglycinamide synthetase, C domain SPICA_RS12275 PF00440 Bacterial regulatory proteins, tetR family SPICA_RS12280 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS12285 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS12295 PF00005 ABC transporter SPICA_RS12295 PF00664 ABC transporter transmembrane region SPICA_RS12300 PF00664 ABC transporter transmembrane region SPICA_RS12300 PF00005 ABC transporter SPICA_RS12310 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS12310 PF07568 Histidine kinase SPICA_RS12310 PF12282 Signal transduction histidine kinase SPICA_RS12315 PF13458 Periplasmic binding protein SPICA_RS12320 PF13193 AMP-binding enzyme C-terminal domain SPICA_RS12320 PF00501 AMP-binding enzyme SPICA_RS12335 PF00890 FAD binding domain SPICA_RS12335 PF14537 Cytochrome c3 SPICA_RS12345 PF01634 ATP phosphoribosyltransferase SPICA_RS12345 PF08029 HisG, C-terminal domain SPICA_RS12350 PF00475 Imidazoleglycerol-phosphate dehydratase SPICA_RS12355 PF00117 Glutamine amidotransferase class-I SPICA_RS12360 PF00977 Histidine biosynthesis protein SPICA_RS12365 PF01502 Phosphoribosyl-AMP cyclohydrolase SPICA_RS12365 PF01503 Phosphoribosyl-ATP pyrophosphohydrolase SPICA_RS12370 PF00155 Aminotransferase class I and II SPICA_RS12375 PF00815 Histidinol dehydrogenase SPICA_RS12400 PF00150 Cellulase (glycosyl hydrolase family 5) SPICA_RS12400 PF00942 Cellulose binding domain SPICA_RS12440 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS12445 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS12450 PF01547 Bacterial extracellular solute-binding protein SPICA_RS12455 PF17851 Beta xylosidase C-terminal Concanavalin A-like domain SPICA_RS12455 PF04616 Glycosyl hydrolases family 43 SPICA_RS12460 PF17851 Beta xylosidase C-terminal Concanavalin A-like domain SPICA_RS12460 PF04616 Glycosyl hydrolases family 43 SPICA_RS12480 PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 SPICA_RS12480 PF13542 Helix-turn-helix domain of transposase family ISL3 SPICA_RS12480 PF01610 Transposase SPICA_RS12495 PF17769 Phosphoribosylaminoimidazole carboxylase C-terminal domain SPICA_RS12495 PF02222 ATP-grasp domain SPICA_RS12500 PF00731 AIR carboxylase SPICA_RS12530 PF00480 ROK family SPICA_RS12535 PF01979 Amidohydrolase family SPICA_RS12540 PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SPICA_RS12545 PF00571 CBS domain SPICA_RS12545 PF01769 Divalent cation transporter SPICA_RS12545 PF03448 MgtE intracellular N domain SPICA_RS12550 PF02537 CrcB-like protein, Camphor Resistance (CrcB) SPICA_RS12555 PF02641 Uncharacterized ACR, COG1993 SPICA_RS12580 PF08331 Domain of unknown function (DUF1730) SPICA_RS12590 PF17147 Pyruvate:ferredoxin oxidoreductase core domain II SPICA_RS12590 PF10371 Domain of unknown function SPICA_RS12590 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPICA_RS12590 PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg SPICA_RS12590 PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase SPICA_RS12595 PF00158 Sigma-54 interaction domain SPICA_RS12595 PF00072 Response regulator receiver domain SPICA_RS12595 PF02954 Bacterial regulatory protein, Fis family SPICA_RS12600 PF00534 Glycosyl transferases group 1 SPICA_RS12605 PF02447 GntP family permease SPICA_RS12610 PF03819 MazG nucleotide pyrophosphohydrolase domain SPICA_RS12615 PF01195 Peptidyl-tRNA hydrolase SPICA_RS12625 PF07085 DRTGG domain SPICA_RS12625 PF02833 DHHA2 domain SPICA_RS12625 PF01368 DHH family SPICA_RS12625 PF00571 CBS domain SPICA_RS12640 PF00574 Clp protease SPICA_RS12645 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPICA_RS12645 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPICA_RS12650 PF00581 Rhodanese-like domain SPICA_RS12660 PF01268 Formate--tetrahydrofolate ligase SPICA_RS12665 PF00842 Alanine racemase, C-terminal domain SPICA_RS12665 PF01168 Alanine racemase, N-terminal domain SPICA_RS12690 PF00005 ABC transporter SPICA_RS12695 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS12700 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPICA_RS12715 PF00881 Nitroreductase family SPICA_RS12725 PF03023 Lipid II flippase MurJ SPICA_RS12730 PF03009 Glycerophosphoryl diester phosphodiesterase family SPICA_RS12740 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPICA_RS12745 PF02254 TrkA-N domain SPICA_RS12745 PF02080 TrkA-C domain SPICA_RS12750 PF02386 Cation transport protein SPICA_RS12755 PF01921 tRNA synthetases class I (K) SPICA_RS12760 PF00403 Heavy-metal-associated domain SPICA_RS12765 PF00403 Heavy-metal-associated domain SPICA_RS12780 PF00563 EAL domain SPICA_RS12780 PF00990 Diguanylate cyclase, GGDEF domain SPICA_RS12780 PF03707 Bacterial signalling protein N terminal repeat SPICA_RS12815 PF00171 Aldehyde dehydrogenase family SPICA_RS12820 PF00860 Permease family SPICA_RS12825 PF01979 Amidohydrolase family SPICA_RS12825 PF13382 Adenine deaminase C-terminal domain SPICA_RS12830 PF13382 Adenine deaminase C-terminal domain SPICA_RS12830 PF01979 Amidohydrolase family SPICA_RS12840 PF00072 Response regulator receiver domain SPICA_RS12855 PF00005 ABC transporter SPICA_RS12855 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SPICA_RS12860 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SPICA_RS12860 PF00005 ABC transporter SPICA_RS12865 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS12865 PF12911 N-terminal TM domain of oligopeptide transport permease C SPICA_RS12870 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS12875 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle SPICA_RS12930 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SPICA_RS12930 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SPICA_RS12935 PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain SPICA_RS12935 PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain SPICA_RS12955 PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family SPICA_RS12960 PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B SPICA_RS12965 PF01180 Dihydroorotate dehydrogenase SPICA_RS12970 PF00156 Phosphoribosyl transferase domain SPICA_RS12995 PF01926 50S ribosome-binding GTPase SPICA_RS12995 PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SPICA_RS13000 PF02896 PEP-utilising enzyme, TIM barrel domain SPICA_RS13000 PF00391 PEP-utilising enzyme, mobile domain SPICA_RS13000 PF05524 PEP-utilising enzyme, N-terminal SPICA_RS13020 PF00211 Adenylate and Guanylate cyclase catalytic domain SPICA_RS13025 PF06745 KaiC SPICA_RS13025 PF18073 Rubredoxin metal binding domain SPICA_RS13030 PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPICA_RS13065 PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain SPICA_RS13065 PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SPICA_RS13065 PF01842 ACT domain SPICA_RS13070 PF00266 Aminotransferase class-V SPICA_RS13075 PF06971 Putative DNA-binding protein N-terminus SPICA_RS13075 PF02629 CoA binding domain SPICA_RS13080 PF02603 HPr Serine kinase N terminus SPICA_RS13080 PF07475 HPr Serine kinase C-terminal domain SPICA_RS13085 PF00381 PTS HPr component phosphorylation site SPICA_RS13090 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS13090 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS13090 PF00989 PAS fold SPICA_RS13090 PF00672 HAMP domain SPICA_RS13095 PF02954 Bacterial regulatory protein, Fis family SPICA_RS13095 PF00072 Response regulator receiver domain SPICA_RS13095 PF00158 Sigma-54 interaction domain SPICA_RS13100 PF00717 Peptidase S24-like SPICA_RS13100 PF01726 LexA DNA binding domain SPICA_RS13110 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPICA_RS13115 PF00348 Polyprenyl synthetase SPICA_RS13120 PF02659 Putative manganese efflux pump SPICA_RS13125 PF17785 PUA-like domain SPICA_RS13125 PF10672 S-adenosylmethionine-dependent methyltransferase SPICA_RS13130 PF17941 Polyphosphate kinase C-terminal domain 1 SPICA_RS13130 PF02503 Polyphosphate kinase middle domain SPICA_RS13130 PF13090 Polyphosphate kinase C-terminal domain 2 SPICA_RS13130 PF13089 Polyphosphate kinase N-terminal domain SPICA_RS13135 PF02541 Ppx/GppA phosphatase family SPICA_RS13140 PF01204 Trehalase SPICA_RS13145 PF02637 GatB domain SPICA_RS13145 PF02934 GatB/GatE catalytic domain SPICA_RS13185 PF00593 TonB dependent receptor SPICA_RS13185 PF07715 TonB-dependent Receptor Plug Domain SPICA_RS13195 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS13200 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPICA_RS13210 PF00072 Response regulator receiver domain SPICA_RS13210 PF00486 Transcriptional regulatory protein, C terminal SPICA_RS13215 PF00672 HAMP domain SPICA_RS13215 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS13215 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS13220 PF00005 ABC transporter SPICA_RS13235 PF00395 S-layer homology domain SPICA_RS13235 PF00331 Glycosyl hydrolase family 10 SPICA_RS13235 PF02018 Carbohydrate binding domain SPICA_RS13235 PF06452 Carbohydrate family 9 binding domain-like SPICA_RS13240 PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPICA_RS13245 PF12729 Four helix bundle sensory module for signal transduction SPICA_RS13245 PF00672 HAMP domain SPICA_RS13245 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS13250 PF00072 Response regulator receiver domain SPICA_RS13260 PF02446 4-alpha-glucanotransferase SPICA_RS13275 PF00291 Pyridoxal-phosphate dependent enzyme SPICA_RS13275 PF14821 Threonine synthase N terminus SPICA_RS13280 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPICA_RS13285 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS13290 PF00005 ABC transporter SPICA_RS13295 PF01451 Low molecular weight phosphotyrosine protein phosphatase SPICA_RS13300 PF01022 Bacterial regulatory protein, arsR family SPICA_RS13310 PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase SPICA_RS13310 PF00393 6-phosphogluconate dehydrogenase, C-terminal domain SPICA_RS13315 PF00356 Bacterial regulatory proteins, lacI family SPICA_RS13320 PF13302 Acetyltransferase (GNAT) domain SPICA_RS13320 PF00117 Glutamine amidotransferase class-I SPICA_RS13320 PF00958 GMP synthase C terminal domain SPICA_RS13320 PF03352 Methyladenine glycosylase SPICA_RS13320 PF13673 Acetyltransferase (GNAT) domain SPICA_RS13325 PF06808 Tripartite ATP-independent periplasmic transporter, DctM component SPICA_RS13335 PF03480 Bacterial extracellular solute-binding protein, family 7 SPICA_RS13340 PF00072 Response regulator receiver domain SPICA_RS13340 PF12833 Helix-turn-helix domain SPICA_RS13345 PF07694 5TMR of 5TMR-LYT SPICA_RS13345 PF06580 Histidine kinase SPICA_RS13380 PF01515 Phosphate acetyl/butaryl transferase SPICA_RS13385 PF00871 Acetokinase family SPICA_RS13400 PF07687 Peptidase dimerisation domain SPICA_RS13400 PF01546 Peptidase family M20/M25/M40 SPICA_RS13420 PF00005 ABC transporter SPICA_RS13435 PF16314 Domain of unknown function (DUF4954) SPICA_RS13440 PF07670 Nucleoside recognition SPICA_RS13445 PF01371 Trp repressor protein SPICA_RS13450 PF00005 ABC transporter SPICA_RS13450 PF16326 ABC transporter C-terminal domain SPICA_RS13450 PF12848 ABC transporter SPICA_RS13455 PF00072 Response regulator receiver domain SPICA_RS13455 PF09308 LuxQ, periplasmic SPICA_RS13455 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS13455 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS13465 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS13470 PF00005 ABC transporter SPICA_RS13475 PF02608 ABC transporter substrate-binding protein PnrA-like SPICA_RS13505 PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system SPICA_RS13520 PF00849 RNA pseudouridylate synthase SPICA_RS13530 PF01435 Peptidase family M48 SPICA_RS13530 PF16491 CAAX prenyl protease N-terminal, five membrane helices SPICA_RS13535 PF00205 Thiamine pyrophosphate enzyme, central domain SPICA_RS13535 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SPICA_RS13535 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPICA_RS13540 PF00920 Dehydratase family SPICA_RS13545 PF00180 Isocitrate/isopropylmalate dehydrogenase SPICA_RS13550 PF08502 LeuA allosteric (dimerisation) domain SPICA_RS13550 PF00682 HMGL-like SPICA_RS13555 PF08502 LeuA allosteric (dimerisation) domain SPICA_RS13555 PF00682 HMGL-like SPICA_RS13560 PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain SPICA_RS13560 PF01450 Acetohydroxy acid isomeroreductase, catalytic domain SPICA_RS13565 PF10369 Small subunit of acetolactate synthase SPICA_RS13570 PF18152 DAHP synthase ferredoxin-like domain SPICA_RS13570 PF00793 DAHP synthetase I family SPICA_RS13575 PF13344 Haloacid dehalogenase-like hydrolase SPICA_RS13590 PF06226 Protein of unknown function (DUF1007) SPICA_RS13595 PF03824 High-affinity nickel-transport protein SPICA_RS13610 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPICA_RS13610 PF01872 RibD C-terminal domain SPICA_RS13615 PF00920 Dehydratase family SPICA_RS13620 PF00330 Aconitase family (aconitate hydratase) SPICA_RS13625 PF00694 Aconitase C-terminal domain SPICA_RS13630 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SPICA_RS13630 PF00205 Thiamine pyrophosphate enzyme, central domain SPICA_RS13630 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPICA_RS13635 PF10369 Small subunit of acetolactate synthase SPICA_RS13640 PF07690 Major Facilitator Superfamily SPICA_RS13655 PF18766 SWI2/SNF2 ATPase SPICA_RS13655 PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) SPICA_RS13655 PF11867 Domain of unknown function (DUF3387) SPICA_RS13665 PF01420 Type I restriction modification DNA specificity domain SPICA_RS13675 PF02384 N-6 DNA Methylase SPICA_RS13685 PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system SPICA_RS13690 PF00672 HAMP domain SPICA_RS13690 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS13690 PF18698 Histidine kinase sensor domain SPICA_RS13690 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS13695 PF01300 Telomere recombination SPICA_RS13695 PF03481 Putative GTP-binding controlling metal-binding SPICA_RS13705 PF01544 CorA-like Mg2+ transporter protein SPICA_RS13710 PF02927 Cellulase N-terminal ig-like domain SPICA_RS13710 PF07679 Immunoglobulin I-set domain SPICA_RS13710 PF00759 Glycosyl hydrolase family 9 SPICA_RS13710 PF02018 Carbohydrate binding domain SPICA_RS13725 PF13419 Haloacid dehalogenase-like hydrolase SPICA_RS13735 PF00133 tRNA synthetases class I (I, L, M and V) SPICA_RS13735 PF13603 Leucyl-tRNA synthetase, Domain 2 SPICA_RS13735 PF09334 tRNA synthetases class I (M) SPICA_RS13735 PF08264 Anticodon-binding domain of tRNA SPICA_RS13740 PF07883 Cupin domain SPICA_RS13750 PF13439 Glycosyltransferase Family 4 SPICA_RS13755 PF01212 Beta-eliminating lyase SPICA_RS13760 PF00557 Metallopeptidase family M24 SPICA_RS13760 PF01321 Creatinase/Prolidase N-terminal domain SPICA_RS13775 PF04324 BFD-like [2Fe-2S] binding domain SPICA_RS13775 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPICA_RS13780 PF01266 FAD dependent oxidoreductase SPICA_RS13780 PF16901 C-terminal domain of alpha-glycerophosphate oxidase SPICA_RS13795 PF08668 HDOD domain SPICA_RS13810 PF02151 UvrB/uvrC motif SPICA_RS13810 PF08459 UvrC Helix-hairpin-helix N-terminal SPICA_RS13810 PF01541 GIY-YIG catalytic domain SPICA_RS13820 PF00309 Sigma-54 factor, Activator interacting domain (AID) SPICA_RS13820 PF04963 Sigma-54 factor, core binding domain SPICA_RS13820 PF04552 Sigma-54, DNA binding domain SPICA_RS13835 PF02557 D-alanyl-D-alanine carboxypeptidase SPICA_RS13855 PF00485 Phosphoribulokinase / Uridine kinase family SPICA_RS13860 PF00209 Sodium:neurotransmitter symporter family SPICA_RS13865 PF00684 DnaJ central domain SPICA_RS13865 PF00226 DnaJ domain SPICA_RS13865 PF01556 DnaJ C terminal domain SPICA_RS13870 PF00012 Hsp70 protein SPICA_RS13875 PF01025 GrpE SPICA_RS13885 PF02673 Bacitracin resistance protein BacA SPICA_RS13890 PF00849 RNA pseudouridylate synthase SPICA_RS13890 PF01479 S4 domain SPICA_RS13900 PF02782 FGGY family of carbohydrate kinases, C-terminal domain SPICA_RS13900 PF00370 FGGY family of carbohydrate kinases, N-terminal domain SPICA_RS13910 PF00486 Transcriptional regulatory protein, C terminal SPICA_RS13910 PF00072 Response regulator receiver domain SPICA_RS13915 PF13581 Histidine kinase-like ATPase domain SPICA_RS13915 PF07568 Histidine kinase SPICA_RS13915 PF13426 PAS domain SPICA_RS13925 PF00005 ABC transporter SPICA_RS13930 PF02405 Permease MlaE SPICA_RS13945 PF00005 ABC transporter SPICA_RS13960 PF13277 YmdB-like protein SPICA_RS13965 PF00013 KH domain SPICA_RS13965 PF01966 HD domain SPICA_RS13965 PF12072 Domain of unknown function (DUF3552) SPICA_RS13970 PF00005 ABC transporter SPICA_RS13970 PF12399 Branched-chain amino acid ATP-binding cassette transporter SPICA_RS13985 PF06418 CTP synthase N-terminus SPICA_RS13985 PF00117 Glutamine amidotransferase class-I SPICA_RS13995 PF03705 CheR methyltransferase, all-alpha domain SPICA_RS13995 PF01739 CheR methyltransferase, SAM binding domain SPICA_RS14000 PF01339 CheB methylesterase SPICA_RS14000 PF00072 Response regulator receiver domain SPICA_RS14010 PF00912 Transglycosylase SPICA_RS14020 PF13277 YmdB-like protein SPICA_RS14035 PF02906 Iron only hydrogenase large subunit, C-terminal domain SPICA_RS14035 PF02256 Iron hydrogenase small subunit SPICA_RS14035 PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region SPICA_RS14035 PF00037 4Fe-4S binding domain SPICA_RS14040 PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SPICA_RS14040 PF00037 4Fe-4S binding domain SPICA_RS14040 PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit SPICA_RS14050 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS14050 PF00672 HAMP domain SPICA_RS14065 PF00501 AMP-binding enzyme SPICA_RS14065 PF13193 AMP-binding enzyme C-terminal domain SPICA_RS14085 PF00478 IMP dehydrogenase / GMP reductase domain SPICA_RS14085 PF00571 CBS domain SPICA_RS14100 PF00132 Bacterial transferase hexapeptide (six repeats) SPICA_RS14105 PF13614 AAA domain SPICA_RS14110 PF17762 HTH domain found in ParB protein SPICA_RS14110 PF02195 ParB-like nuclease domain SPICA_RS14115 PF02954 Bacterial regulatory protein, Fis family SPICA_RS14115 PF00158 Sigma-54 interaction domain SPICA_RS14115 PF00072 Response regulator receiver domain SPICA_RS14120 PF08032 RNA 2'-O ribose methyltransferase substrate binding SPICA_RS14120 PF00588 SpoU rRNA Methylase family SPICA_RS14130 PF00291 Pyridoxal-phosphate dependent enzyme SPICA_RS14175 PF00005 ABC transporter SPICA_RS14180 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS14190 PF03949 Malic enzyme, NAD binding domain SPICA_RS14190 PF00390 Malic enzyme, N-terminal domain SPICA_RS14205 PF03611 PTS system sugar-specific permease component SPICA_RS14210 PF04073 Aminoacyl-tRNA editing domain SPICA_RS14210 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPICA_RS14210 PF03129 Anticodon binding domain SPICA_RS14220 PF00343 Carbohydrate phosphorylase SPICA_RS14230 PF01636 Phosphotransferase enzyme family SPICA_RS14235 PF01118 Semialdehyde dehydrogenase, NAD binding domain SPICA_RS14240 PF02653 Branched-chain amino acid transport system / permease component SPICA_RS14245 PF00005 ABC transporter SPICA_RS14250 PF13407 Periplasmic binding protein domain SPICA_RS14255 PF00455 DeoR C terminal sensor domain SPICA_RS14255 PF08220 DeoR-like helix-turn-helix domain SPICA_RS14260 PF00005 ABC transporter SPICA_RS14265 PF00596 Class II Aldolase and Adducin N-terminal domain SPICA_RS14270 PF02610 L-arabinose isomerase SPICA_RS14270 PF11762 L-arabinose isomerase C-terminal domain SPICA_RS14280 PF01554 MatE SPICA_RS14285 PF03422 Carbohydrate binding module (family 6) SPICA_RS14285 PF00756 Putative esterase SPICA_RS14285 PF00331 Glycosyl hydrolase family 10 SPICA_RS14285 PF00404 Dockerin type I domain SPICA_RS14305 PF08032 RNA 2'-O ribose methyltransferase substrate binding SPICA_RS14305 PF00588 SpoU rRNA Methylase family SPICA_RS14310 PF10996 Beta-Casp domain SPICA_RS14310 PF00753 Metallo-beta-lactamase superfamily SPICA_RS14310 PF07521 Zn-dependent metallo-hydrolase RNA specificity domain SPICA_RS14315 PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase SPICA_RS14315 PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase SPICA_RS14330 PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SPICA_RS14335 PF02965 Vitamin B12 dependent methionine synthase, activation domain SPICA_RS14335 PF00809 Pterin binding enzyme SPICA_RS14335 PF02310 B12 binding domain SPICA_RS14335 PF02607 B12 binding domain SPICA_RS14335 PF02574 Homocysteine S-methyltransferase SPICA_RS14355 PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) SPICA_RS14360 PF00005 ABC transporter SPICA_RS14370 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS14370 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS14375 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPICA_RS14375 PF00128 Alpha amylase, catalytic domain SPICA_RS14390 PF02080 TrkA-C domain SPICA_RS14390 PF02254 TrkA-N domain SPICA_RS14395 PF02386 Cation transport protein SPICA_RS14405 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS14410 PF00528 Binding-protein-dependent transport system inner membrane component SPICA_RS14415 PF01547 Bacterial extracellular solute-binding protein SPICA_RS14420 PF01418 Helix-turn-helix domain, rpiR family SPICA_RS14420 PF01380 SIS domain SPICA_RS14425 PF00107 Zinc-binding dehydrogenase SPICA_RS14425 PF08240 Alcohol dehydrogenase GroES-like domain SPICA_RS14430 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SPICA_RS14430 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SPICA_RS14435 PF17863 AAA lid domain SPICA_RS14435 PF07726 ATPase family associated with various cellular activities (AAA) SPICA_RS14450 PF06803 Protein of unknown function (DUF1232) SPICA_RS14460 PF00501 AMP-binding enzyme SPICA_RS14465 PF02773 S-adenosylmethionine synthetase, C-terminal domain SPICA_RS14465 PF00438 S-adenosylmethionine synthetase, N-terminal domain SPICA_RS14465 PF02772 S-adenosylmethionine synthetase, central domain SPICA_RS14470 PF03462 PCRF domain SPICA_RS14470 PF00472 RF-1 domain SPICA_RS14485 PF00877 NlpC/P60 family SPICA_RS14510 PF03989 DNA gyrase C-terminal domain, beta-propeller SPICA_RS14510 PF00521 DNA gyrase/topoisomerase IV, subunit A SPICA_RS14515 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS14515 PF00986 DNA gyrase B subunit, carboxyl terminus SPICA_RS14515 PF00204 DNA gyrase B SPICA_RS14515 PF01751 Toprim domain SPICA_RS14530 PF00072 Response regulator receiver domain SPICA_RS14540 PF01055 Glycosyl hydrolases family 31 SPICA_RS14540 PF13802 Galactose mutarotase-like SPICA_RS14540 PF17137 Domain of unknown function (DUF5110) SPICA_RS14540 PF16338 Domain of unknown function (DUF4968) SPICA_RS14565 PF00072 Response regulator receiver domain SPICA_RS14565 PF00990 Diguanylate cyclase, GGDEF domain SPICA_RS14575 PF00218 Indole-3-glycerol phosphate synthase SPICA_RS14580 PF00684 DnaJ central domain SPICA_RS14580 PF01556 DnaJ C terminal domain SPICA_RS14580 PF00226 DnaJ domain SPICA_RS14595 PF01458 Uncharacterized protein family (UPF0051) SPICA_RS14640 PF00565 Staphylococcal nuclease homologue SPICA_RS14645 PF00005 ABC transporter SPICA_RS14660 PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase SPICA_RS14660 PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SPICA_RS14665 PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain SPICA_RS14665 PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase SPICA_RS14685 PF02001 Protein of unknown function DUF134 SPICA_RS14690 PF00440 Bacterial regulatory proteins, tetR family SPICA_RS14695 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS14695 PF07568 Histidine kinase SPICA_RS14695 PF12282 Signal transduction histidine kinase SPICA_RS14710 PF02203 Tar ligand binding domain homologue SPICA_RS14710 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS14710 PF00672 HAMP domain SPICA_RS14745 PF16258 Domain of unknown function (DUF4912) SPICA_RS14785 PF00672 HAMP domain SPICA_RS14785 PF02743 Cache domain SPICA_RS14785 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS14790 PF00293 NUDIX domain SPICA_RS14790 PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain SPICA_RS14790 PF09297 NADH pyrophosphatase zinc ribbon domain SPICA_RS14795 PF13482 RNase_H superfamily SPICA_RS14800 PF02508 Rnf-Nqr subunit, membrane protein SPICA_RS14810 PF00535 Glycosyl transferase family 2 SPICA_RS14825 PF00211 Adenylate and Guanylate cyclase catalytic domain SPICA_RS14825 PF00672 HAMP domain SPICA_RS14890 PF00672 HAMP domain SPICA_RS14890 PF17202 Single cache domain 3 SPICA_RS14890 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS14895 PF03707 Bacterial signalling protein N terminal repeat SPICA_RS14895 PF00990 Diguanylate cyclase, GGDEF domain SPICA_RS14895 PF00563 EAL domain SPICA_RS14900 PF03009 Glycerophosphoryl diester phosphodiesterase family SPICA_RS14905 PF02834 LigT like Phosphoesterase SPICA_RS14915 PF07691 PA14 domain SPICA_RS14915 PF00728 Glycosyl hydrolase family 20, catalytic domain SPICA_RS14915 PF02838 Glycosyl hydrolase family 20, domain 2 SPICA_RS14925 PF07568 Histidine kinase SPICA_RS14925 PF12282 Signal transduction histidine kinase SPICA_RS14925 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS14930 PF04225 Opacity-associated protein A LysM-like domain SPICA_RS14930 PF01551 Peptidase family M23 SPICA_RS14935 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS14935 PF02203 Tar ligand binding domain homologue SPICA_RS14935 PF00672 HAMP domain SPICA_RS14950 PF00072 Response regulator receiver domain SPICA_RS14955 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS14955 PF07730 Histidine kinase SPICA_RS14955 PF00672 HAMP domain SPICA_RS14960 PF00072 Response regulator receiver domain SPICA_RS15000 PF02743 Cache domain SPICA_RS15000 PF00672 HAMP domain SPICA_RS15000 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS15005 PF09587 Bacterial capsule synthesis protein PGA_cap SPICA_RS15010 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPICA_RS15010 PF08448 PAS fold SPICA_RS15010 PF00512 His Kinase A (phospho-acceptor) domain SPICA_RS15010 PF00072 Response regulator receiver domain SPICA_RS15010 PF13188 PAS domain SPICA_RS15015 PF12833 Helix-turn-helix domain SPICA_RS15030 PF01555 DNA methylase SPICA_RS15035 PF01555 DNA methylase SPICA_RS15040 PF04851 Type III restriction enzyme, res subunit SPICA_RS15060 PF03781 Sulfatase-modifying factor enzyme 1 SPICA_RS15070 PF00672 HAMP domain SPICA_RS15070 PF02743 Cache domain SPICA_RS15070 PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain SPICA_RS15075 PF01979 Amidohydrolase family SPICA_RS15080 PF00300 Histidine phosphatase superfamily (branch 1) SPICA_RS15085 PF00990 Diguanylate cyclase, GGDEF domain SPICA_RS15090 PF00877 NlpC/P60 family SPICA_RS15100 PF02311 AraC-like ligand binding domain SPICA_RS15100 PF12833 Helix-turn-helix domain