locus-tag	class	description
FUT84_RS00010	COG0592	DNA-directed DNA polymerase activity
FUT84_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FUT84_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FUT84_RS00040	COG0733	neurotransmitter:sodium symporter activity
FUT84_RS00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FUT84_RS00050	COG0765	amino acid transport
FUT84_RS00065	COG1924	4 iron, 4 sulfur cluster binding
FUT84_RS00075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FUT84_RS00080	COG0564	pseudouridine synthase activity
FUT84_RS00085	COG2195	Cleaves the N-terminal amino acid of tripeptides
FUT84_RS00090	COG4555	ABC transporter
FUT84_RS00110	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FUT84_RS00120	COG0731	radical SAM domain protein
FUT84_RS00130	COG0423	glycine-tRNA ligase activity
FUT84_RS00135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FUT84_RS00165	COG1349	DNA-binding transcription factor activity
FUT84_RS00180	COG2211	Major facilitator Superfamily
FUT84_RS00185	COG3250	beta-galactosidase activity
FUT84_RS00190	COG1904	glucuronate isomerase
FUT84_RS00210	COG0246	Mannitol dehydrogenase
FUT84_RS00215	COG1312	Catalyzes the dehydration of D-mannonate
FUT84_RS00225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FUT84_RS00230	COG0628	permease
FUT84_RS00245	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FUT84_RS00260	COG0442	prolyl-tRNA aminoacylation
FUT84_RS00265	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FUT84_RS00275	COG1454	alcohol dehydrogenase
FUT84_RS00275	COG1012	belongs to the aldehyde dehydrogenase family
FUT84_RS00295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FUT84_RS00310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FUT84_RS00310	COG1747	RNA polymerase binding
FUT84_RS00320	COG2183	response to ionizing radiation
FUT84_RS00355	COG0018	arginyl-trna synthetase
FUT84_RS00370	COG0840	transmembrane signaling receptor activity
FUT84_RS00375	COG0420	3'-5' exonuclease activity
FUT84_RS00380	COG0419	ATPase involved in DNA repair
FUT84_RS00390	COG0488	(ABC) transporter
FUT84_RS00400	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FUT84_RS00405	COG0793	Belongs to the peptidase S41A family
FUT84_RS00410	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FUT84_RS00425	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FUT84_RS00440	COG0673	inositol 2-dehydrogenase activity
FUT84_RS00455	COG1191	sigma factor activity
FUT84_RS00460	COG1847	R3H domain protein
FUT84_RS00480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FUT84_RS00495	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FUT84_RS00500	COG1469	GTP cyclohydrolase I activity
FUT84_RS00515	COG0863	Belongs to the N(4) N(6)-methyltransferase family
FUT84_RS00525	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FUT84_RS00550	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FUT84_RS00555	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FUT84_RS00575	COG3956	TIGRFAM MazG family protein
FUT84_RS00595	COG2801	Transposase and inactivated derivatives
FUT84_RS00605	COG0840	transmembrane signaling receptor activity
FUT84_RS00620	COG1102	Psort location Cytoplasmic, score
FUT84_RS00760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FUT84_RS00860	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FUT84_RS00935	COG2376	Dihydroxyacetone kinase
FUT84_RS00955	COG0557	exoribonuclease II activity
FUT84_RS00975	COG1129	ABC transporter
FUT84_RS00995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FUT84_RS01030	COG5377	YqaJ viral recombinase family
FUT84_RS01050	COG3723	Recombinational DNA repair protein, rece pathway
FUT84_RS01115	COG0629	single-stranded DNA binding
FUT84_RS01415	COG1234	tRNA 3'-trailer cleavage
FUT84_RS01420	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FUT84_RS01455	COG3885	ferrous iron binding
FUT84_RS01455	COG2078	PFAM AMMECR1 domain protein
FUT84_RS01460	COG1022	Amp-dependent synthetase and ligase
FUT84_RS01465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FUT84_RS01470	COG1486	melibiose metabolic process
FUT84_RS01480	COG3216	Uncharacterized protein conserved in bacteria (DUF2062)
FUT84_RS01485	COG2982	Protein involved in outer membrane biogenesis
FUT84_RS01490	COG0697	spore germination
FUT84_RS01500	COG0217	transcriptional regulatory protein
FUT84_RS01510	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FUT84_RS01515	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FUT84_RS01520	COG0840	transmembrane signaling receptor activity
FUT84_RS01535	COG3842	ATPase activity
FUT84_RS01540	COG1178	ABC-type Fe3 transport system permease component
FUT84_RS01545	COG3842	ATPase activity
FUT84_RS01555	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FUT84_RS01590	COG0656	L-ascorbic acid biosynthetic process
FUT84_RS01625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FUT84_RS01660	COG1151	hydroxylamine reductase activity
FUT84_RS01685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FUT84_RS01685	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FUT84_RS01685	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FUT84_RS01695	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FUT84_RS01700	COG0058	SHG alpha-glucan phosphorylase activity
FUT84_RS01705	COG0235	Class ii aldolase
FUT84_RS01715	COG1063	alcohol dehydrogenase
FUT84_RS01720	COG1349	DNA-binding transcription factor activity
FUT84_RS01725	COG2213	PTS system mannitol-specific
FUT84_RS01725	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT84_RS01730	COG1690	Belongs to the RtcB family
FUT84_RS01735	COG1164	Oligoendopeptidase f
FUT84_RS01750	COG0840	transmembrane signaling receptor activity
FUT84_RS01760	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FUT84_RS01780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FUT84_RS01800	COG1360	Flagellar Motor Protein
FUT84_RS01805	COG1580	Controls the rotational direction of flagella during chemotaxis
FUT84_RS01810	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FUT84_RS01815	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FUT84_RS01815	COG1776	CheC inhibitor of MCP methylation
FUT84_RS01825	COG1338	Plays a role in the flagellum-specific transport system
FUT84_RS01830	COG1987	bacterial-type flagellum assembly
FUT84_RS01835	COG1684	flagellar biosynthetic protein fliR
FUT84_RS01840	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FUT84_RS01845	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FUT84_RS01850	COG1419	protein localization to endoplasmic reticulum
FUT84_RS01860	COG3437	response regulator, receiver
FUT84_RS01865	COG1671	Belongs to the UPF0178 family
FUT84_RS01875	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FUT84_RS01885	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FUT84_RS01900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FUT84_RS01905	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FUT84_RS01920	COG0237	dephospho-CoA kinase activity
FUT84_RS01925	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FUT84_RS01930	COG0710	3-dehydroquinate dehydratase activity
FUT84_RS01930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FUT84_RS01945	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FUT84_RS01955	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FUT84_RS01965	COG0739	heme binding
FUT84_RS01980	COG1774	PSP1 C-terminal conserved region
FUT84_RS02010	COG1078	dGTPase activity
FUT84_RS02015	COG2033	superoxide reductase activity
FUT84_RS02020	COG2823	Periplasmic or secreted lipoprotein
FUT84_RS02020	COG1652	LysM domain
FUT84_RS02030	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FUT84_RS02035	COG0051	transcription antitermination factor activity, RNA binding
FUT84_RS02040	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FUT84_RS02045	COG0088	Forms part of the polypeptide exit tunnel
FUT84_RS02050	COG0089	rRNA binding
FUT84_RS02055	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FUT84_RS02065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FUT84_RS02070	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FUT84_RS02080	COG0255	Belongs to the universal ribosomal protein uL29 family
FUT84_RS02085	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FUT84_RS02100	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FUT84_RS02110	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FUT84_RS02115	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FUT84_RS02120	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FUT84_RS02130	COG1841	ribosomal large subunit assembly
FUT84_RS02135	COG0200	Binds to the 23S rRNA
FUT84_RS02145	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FUT84_RS02155	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FUT84_RS02160	COG0202	RNA polymerase activity
FUT84_RS02165	COG0203	ribosomal protein L17
FUT84_RS02195	COG0848	biopolymer transport protein
FUT84_RS02200	COG0811	peptide transport
FUT84_RS02235	COG0519	Catalyzes the synthesis of GMP from XMP
FUT84_RS02245	COG0519	Catalyzes the synthesis of GMP from XMP
FUT84_RS02300	COG0564	pseudouridine synthase activity
FUT84_RS02300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FUT84_RS02320	COG0823	Involved in the tonB-independent uptake of proteins
FUT84_RS02340	COG5341	Protein conserved in bacteria
FUT84_RS02345	COG1752	Esterase of the alpha-beta hydrolase superfamily
FUT84_RS02350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FUT84_RS02365	COG0840	transmembrane signaling receptor activity
FUT84_RS02375	COG1968	undecaprenyl-diphosphatase activity
FUT84_RS02380	COG1674	ftsk spoiiie
FUT84_RS02395	COG0482	sulfurtransferase activity
FUT84_RS02460	COG0166	Belongs to the GPI family
FUT84_RS02470	COG4585	Histidine kinase
FUT84_RS02475	COG2197	response regulator
FUT84_RS02490	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FUT84_RS02510	COG0330	HflC and HflK could
FUT84_RS02525	COG2084	Dehydrogenase
FUT84_RS02535	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FUT84_RS02545	COG1653	transport
FUT84_RS02555	COG0395	ABC-type sugar transport system, permease component
FUT84_RS02575	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FUT84_RS02580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FUT84_RS02585	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FUT84_RS02590	COG1722	exodeoxyribonuclease VII activity
FUT84_RS02595	COG1966	Carbon starvation protein
FUT84_RS02600	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FUT84_RS02625	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FUT84_RS02630	COG0534	Mate efflux family protein
FUT84_RS02635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FUT84_RS02645	COG0549	Belongs to the carbamate kinase family
FUT84_RS02650	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FUT84_RS02655	COG2235	arginine
FUT84_RS02665	COG0018	arginyl-trna synthetase
FUT84_RS02675	COG1702	phosphate starvation-inducible protein PhoH
FUT84_RS02680	COG1480	7TM receptor with intracellular HD hydrolase
FUT84_RS02685	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FUT84_RS02715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FUT84_RS02720	COG2086	electron transfer activity
FUT84_RS02725	COG1960	acyl-CoA dehydrogenase activity
FUT84_RS02735	COG1252	NADH dehydrogenase
FUT84_RS02750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FUT84_RS02765	COG0840	transmembrane signaling receptor activity
FUT84_RS02770	COG0655	NAD(P)H dehydrogenase (quinone) activity
FUT84_RS02795	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FUT84_RS02800	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FUT84_RS02805	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FUT84_RS02820	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FUT84_RS02825	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FUT84_RS02830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FUT84_RS02835	COG1114	Component of the transport system for branched-chain amino acids
FUT84_RS02840	COG0436	Aminotransferase
FUT84_RS02845	COG1522	sequence-specific DNA binding
FUT84_RS02855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FUT84_RS02870	COG0210	DNA helicase
FUT84_RS02905	COG3385	transposase activity
FUT84_RS02910	COG0514	ATP-dependent DNA helicase (RecQ)
FUT84_RS02930	COG0840	transmembrane signaling receptor activity
FUT84_RS02955	COG0514	ATP-dependent DNA helicase (RecQ)
FUT84_RS02975	COG0840	transmembrane signaling receptor activity
FUT84_RS02990	COG0840	transmembrane signaling receptor activity
FUT84_RS03020	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FUT84_RS03035	COG0840	transmembrane signaling receptor activity
FUT84_RS03070	COG0840	transmembrane signaling receptor activity
FUT84_RS03075	COG3385	transposase activity
FUT84_RS03085	COG3177	Filamentation induced by cAMP protein fic
FUT84_RS03095	COG2217	Heavy metal translocating P-type atpase
FUT84_RS03105	COG0640	Transcriptional regulator
FUT84_RS03155	COG0431	NADPH-dependent FMN reductase
FUT84_RS03155	COG3976	FMN-binding domain protein
FUT84_RS03155	COG1053	succinate dehydrogenase
FUT84_RS03200	COG0840	transmembrane signaling receptor activity
FUT84_RS03230	COG0357	Ribosomal RNA small subunit methyltransferase G
FUT84_RS03235	COG1757	Na H antiporter
FUT84_RS03265	COG1253	flavin adenine dinucleotide binding
FUT84_RS03280	COG1882	Formate acetyltransferase
FUT84_RS03285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FUT84_RS03315	COG2198	Histidine kinase
FUT84_RS03315	COG0643	Histidine kinase
FUT84_RS03320	COG0835	chemotaxis
FUT84_RS03330	COG2201	protein-glutamate methylesterase activity
FUT84_RS03340	COG1196	nuclear chromosome segregation
FUT84_RS03350	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FUT84_RS03355	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FUT84_RS03380	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FUT84_RS03395	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FUT84_RS03400	COG2088	sporulation resulting in formation of a cellular spore
FUT84_RS03410	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FUT84_RS03415	COG0037	tRNA processing
FUT84_RS03420	COG0457	Tetratricopeptide repeat
FUT84_RS03425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FUT84_RS03430	COG0481	GTPase activity
FUT84_RS03465	COG2885	chlorophyll binding
FUT84_RS03475	COG1335	isochorismatase
FUT84_RS03480	COG3142	Participates in the control of copper homeostasis
FUT84_RS03490	COG4988	ABC transporter
FUT84_RS03495	COG1132	(ABC) transporter
FUT84_RS03505	COG1137	ATPase activity
FUT84_RS03535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FUT84_RS03545	COG0701	Predicted permease
FUT84_RS03570	COG1131	(ABC) transporter
FUT84_RS03575	COG1028	Short-chain dehydrogenase reductase Sdr
FUT84_RS03590	COG0154	amidase activity
FUT84_RS03595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FUT84_RS03600	COG0124	histidyl-tRNA synthetase
FUT84_RS03610	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FUT84_RS03615	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FUT84_RS03620	COG0579	oxidoreductase
FUT84_RS03635	COG0728	peptidoglycan biosynthetic process
FUT84_RS03640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FUT84_RS03715	COG1271	oxidase subunit
FUT84_RS03720	COG1294	oxidase, subunit
FUT84_RS03725	COG4988	ABC transporter
FUT84_RS03730	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FUT84_RS03735	COG0328	RNA-DNA hybrid ribonuclease activity
FUT84_RS03740	COG4443	Transcriptional Coactivator p15 (PC4)
FUT84_RS03750	COG0708	Exodeoxyribonuclease III
FUT84_RS03755	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FUT84_RS03760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FUT84_RS03760	COG1263	PTS System
FUT84_RS03775	COG0183	Belongs to the thiolase family
FUT84_RS03780	COG1960	acyl-CoA dehydrogenase activity
FUT84_RS03785	COG0426	domain, Protein
FUT84_RS03795	COG1250	3-hydroxyacyl-CoA dehydrogenase
FUT84_RS03800	COG1024	Enoyl-CoA hydratase
FUT84_RS03805	COG0427	acetyl-CoA hydrolase
FUT84_RS03815	COG0297	glycogen (starch) synthase activity
FUT84_RS03820	COG0101	tRNA pseudouridine synthase activity
FUT84_RS03840	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FUT84_RS03845	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FUT84_RS03850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FUT84_RS03860	COG2056	Na+-H+ antiporter family
FUT84_RS03865	COG2986	histidine ammonia-lyase
FUT84_RS03900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FUT84_RS03905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FUT84_RS03915	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FUT84_RS03915	COG0493	'glutamate synthase
FUT84_RS03920	COG0402	S-adenosylhomocysteine deaminase activity
FUT84_RS03930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FUT84_RS03935	COG3608	succinylglutamate desuccinylase aspartoacylase
FUT84_RS03935	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FUT84_RS03940	COG1058	Belongs to the CinA family
FUT84_RS03940	COG1546	Belongs to the CinA family
FUT84_RS03945	COG0315	cyclic pyranopterin monophosphate synthase activity
FUT84_RS03960	COG0521	Mo-molybdopterin cofactor biosynthetic process
FUT84_RS03970	COG0725	ABC transporter, periplasmic molybdate-binding protein
FUT84_RS03975	COG4149	molybdate abc transporter
FUT84_RS03980	COG3842	ATPase activity
FUT84_RS03985	COG0746	molybdenum cofactor guanylyltransferase activity
FUT84_RS03990	COG3608	succinylglutamate desuccinylase aspartoacylase
FUT84_RS03990	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FUT84_RS04000	COG0709	Synthesizes selenophosphate from selenide and ATP
FUT84_RS04015	COG1104	cysteine desulfurase activity
FUT84_RS04025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FUT84_RS04030	COG0772	Belongs to the SEDS family
FUT84_RS04035	COG0768	penicillin binding
FUT84_RS04050	COG1077	Cell shape determining protein MreB Mrl
FUT84_RS04070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FUT84_RS04075	COG0358	DNA primase activity
FUT84_RS04080	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FUT84_RS04090	COG1234	tRNA 3'-trailer cleavage
FUT84_RS04110	COG4656	Part of a membrane complex involved in electron transport
FUT84_RS04115	COG4658	electron transport chain
FUT84_RS04125	COG4660	Part of a membrane complex involved in electron transport
FUT84_RS04130	COG4657	Part of a membrane complex involved in electron transport
FUT84_RS04135	COG2878	Part of a membrane complex involved in electron transport
FUT84_RS04135	COG1245	4Fe-4S binding domain
FUT84_RS04140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FUT84_RS04155	COG1598	PFAM Uncharacterised protein family UPF0150
FUT84_RS04170	COG2211	Major facilitator Superfamily
FUT84_RS04175	COG3064	Membrane
FUT84_RS04190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FUT84_RS04195	COG0024	Methionine aminopeptidase
FUT84_RS04200	COG0484	heat shock protein binding
FUT84_RS04240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FUT84_RS04250	COG0006	proline dipeptidase activity
FUT84_RS04255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FUT84_RS04260	COG1199	ATP-dependent helicase activity
FUT84_RS04275	COG0167	dihydroorotate dehydrogenase activity
FUT84_RS04305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FUT84_RS04315	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FUT84_RS04335	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FUT84_RS04340	COG2197	response regulator
FUT84_RS04475	COG3621	Patatin-like phospholipase
FUT84_RS04515	COG2378	regulation of single-species biofilm formation
FUT84_RS04525	COG0786	glutamate:sodium symporter activity
FUT84_RS04530	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FUT84_RS04555	COG0789	Transcriptional regulator
FUT84_RS04580	COG0588	phosphoglycerate mutase activity
FUT84_RS04585	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FUT84_RS04595	COG0149	triose-phosphate isomerase activity
FUT84_RS04600	COG0126	phosphoglycerate kinase activity
FUT84_RS04625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FUT84_RS04630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FUT84_RS04635	COG0826	peptidase U32
FUT84_RS04670	COG0433	COG0433 Predicted ATPase
FUT84_RS04705	COG0840	transmembrane signaling receptor activity
FUT84_RS04715	COG0778	Nitroreductase
FUT84_RS04755	COG1744	ABC transporter substrate-binding protein PnrA-like
FUT84_RS04760	COG3845	ABC transporter
FUT84_RS04765	COG4603	Belongs to the binding-protein-dependent transport system permease family
FUT84_RS04770	COG1079	Belongs to the binding-protein-dependent transport system permease family
FUT84_RS04775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FUT84_RS04840	COG0049	tRNA binding
FUT84_RS04845	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FUT84_RS04860	COG1053	succinate dehydrogenase
FUT84_RS04865	COG2081	HI0933 family
FUT84_RS04870	COG0187	DNA topoisomerase II activity
FUT84_RS04950	COG1285	pathogenesis
FUT84_RS04955	COG3330	Domain of unknown function (DUF4912)
FUT84_RS04970	COG0455	bacterial-type flagellum organization
FUT84_RS04980	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FUT84_RS05000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FUT84_RS05005	COG0740	serine-type endopeptidase activity
FUT84_RS05010	COG0544	peptidyl-prolyl cis-trans isomerase activity
FUT84_RS05055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FUT84_RS05055	COG3116	cell division
FUT84_RS05060	COG0084	hydrolase, TatD family'
FUT84_RS05090	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FUT84_RS05100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FUT84_RS05110	COG0360	Binds together with S18 to 16S ribosomal RNA
FUT84_RS05115	COG0629	single-stranded DNA binding
FUT84_RS05120	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FUT84_RS05125	COG0359	binds to the 23S rRNA
FUT84_RS05130	COG0305	Participates in initiation and elongation during chromosome replication
FUT84_RS05170	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FUT84_RS05175	COG1160	GTP binding
FUT84_RS05210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FUT84_RS05210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FUT84_RS05210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT84_RS05235	COG0484	heat shock protein binding
FUT84_RS05240	COG0443	Heat shock 70 kDa protein
FUT84_RS05245	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FUT84_RS05250	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FUT84_RS05255	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FUT84_RS05275	COG1269	ATP hydrolysis coupled proton transport
FUT84_RS05280	COG1527	subunit (C
FUT84_RS05290	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FUT84_RS05290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FUT84_RS05290	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT84_RS05295	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FUT84_RS05310	COG2313	pseudouridylate synthase activity
FUT84_RS05315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FUT84_RS05320	COG2001	Belongs to the MraZ family
FUT84_RS05325	COG0275	rRNA processing
FUT84_RS05335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FUT84_RS05340	COG0772	Belongs to the SEDS family
FUT84_RS05345	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FUT84_RS05355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FUT84_RS05360	COG4974	Belongs to the 'phage' integrase family
FUT84_RS05370	COG0758	DNA mediated transformation
FUT84_RS05375	COG0551	DNA topoisomerase type I activity
FUT84_RS05375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FUT84_RS05380	COG4974	Belongs to the 'phage' integrase family
FUT84_RS05385	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FUT84_RS05390	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FUT84_RS05400	COG1815	bacterial-type flagellum-dependent cell motility
FUT84_RS05415	COG1766	The M ring may be actively involved in energy transduction
FUT84_RS05425	COG1317	bacterial-type flagellum organization
FUT84_RS05430	COG1157	protein secretion by the type III secretion system
FUT84_RS05445	COG0019	diaminopimelate decarboxylase activity
FUT84_RS05460	COG0438	transferase activity, transferring glycosyl groups
FUT84_RS05485	COG2186	Transcriptional regulator
FUT84_RS05510	COG0277	FAD linked oxidase domain protein
FUT84_RS05520	COG1490	D-aminoacyl-tRNA deacylase activity
FUT84_RS05525	COG0193	aminoacyl-tRNA hydrolase activity
FUT84_RS05545	COG1473	amidohydrolase
FUT84_RS05560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FUT84_RS05595	COG2217	Heavy metal translocating P-type atpase
FUT84_RS05600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FUT84_RS05605	COG0813	purine-nucleoside phosphorylase activity
FUT84_RS05610	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FUT84_RS05620	COG0840	transmembrane signaling receptor activity
FUT84_RS05650	COG2003	Belongs to the UPF0758 family
FUT84_RS05680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FUT84_RS05695	COG0300	oxidoreductase activity
FUT84_RS05700	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FUT84_RS05705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FUT84_RS05710	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FUT84_RS05725	COG3630	sodium ion export across plasma membrane
FUT84_RS05730	COG0511	ligase activity, forming carbon-carbon bonds
FUT84_RS05730	COG5016	pyruvate
FUT84_RS05740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FUT84_RS05745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FUT84_RS05760	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FUT84_RS05765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FUT84_RS05775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FUT84_RS05780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FUT84_RS05785	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FUT84_RS05845	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FUT84_RS05860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FUT84_RS05875	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FUT84_RS05895	COG0542	response to heat
FUT84_RS05915	COG0826	peptidase U32
FUT84_RS05940	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FUT84_RS05985	COG1366	Belongs to the anti-sigma-factor antagonist family
FUT84_RS05995	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FUT84_RS06005	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FUT84_RS06010	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FUT84_RS06040	COG1640	4-alpha-glucanotransferase
FUT84_RS06060	COG1136	(ABC) transporter
FUT84_RS06060	COG0577	efflux transmembrane transporter activity
FUT84_RS06065	COG0672	)-iron permease
FUT84_RS06070	COG3470	protein probably involved in high-affinity Fe2 transport
FUT84_RS06085	COG0577	efflux transmembrane transporter activity
FUT84_RS06085	COG1136	(ABC) transporter
FUT84_RS06100	COG1136	(ABC) transporter
FUT84_RS06120	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FUT84_RS06120	COG3976	FMN-binding domain protein
FUT84_RS06125	COG2070	2-Nitropropane dioxygenase
FUT84_RS06130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FUT84_RS06150	COG0739	heme binding
FUT84_RS06170	COG0666	response to abiotic stimulus
FUT84_RS06205	COG2502	aspartate--ammonia ligase
FUT84_RS06210	COG1704	LemA family
FUT84_RS06220	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FUT84_RS06250	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FUT84_RS06255	COG0301	tRNA thio-modification
FUT84_RS06270	COG4786	Flagellar basal body rod
FUT84_RS06280	COG2188	Transcriptional regulator
FUT84_RS06285	COG1263	PTS System
FUT84_RS06285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FUT84_RS06285	COG2190	(PTS) system
FUT84_RS06290	COG0561	phosphatase activity
FUT84_RS06295	COG2723	6-phospho-beta-galactosidase activity
FUT84_RS06320	COG5002	protein histidine kinase activity
FUT84_RS06320	COG5001	Diguanylate cyclase
FUT84_RS06325	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FUT84_RS06325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FUT84_RS06335	COG3118	belongs to the thioredoxin family
FUT84_RS06340	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FUT84_RS06350	COG1516	flagellar protein fliS
FUT84_RS06355	COG0840	transmembrane signaling receptor activity
FUT84_RS06375	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FUT84_RS06385	COG4946	Tricorn protease homolog
FUT84_RS06385	COG1506	peptidase
FUT84_RS06385	COG0823	Involved in the tonB-independent uptake of proteins
FUT84_RS06390	COG0840	transmembrane signaling receptor activity
FUT84_RS06395	COG5002	protein histidine kinase activity
FUT84_RS06405	COG0704	Plays a role in the regulation of phosphate uptake
FUT84_RS06410	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FUT84_RS06415	COG0581	inorganic phosphate transmembrane transporter activity
FUT84_RS06420	COG0573	inorganic phosphate transmembrane transporter activity
FUT84_RS06425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FUT84_RS06455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FUT84_RS06495	COG3052	prosthetic group binding
FUT84_RS06525	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FUT84_RS06545	COG1129	ABC transporter
FUT84_RS06570	COG2226	methyltransferase
FUT84_RS06615	COG3177	Filamentation induced by cAMP protein fic
FUT84_RS06645	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FUT84_RS06645	COG0551	DNA topoisomerase type I activity
FUT84_RS06825	COG1132	(ABC) transporter
FUT84_RS06830	COG1132	(ABC) transporter
FUT84_RS06835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FUT84_RS06840	COG1120	ATPase activity
FUT84_RS06855	COG1309	transcriptional regulator
FUT84_RS06860	COG3848	Pyruvate phosphate dikinase
FUT84_RS06860	COG0574	Belongs to the PEP-utilizing enzyme family
FUT84_RS06870	COG1129	ABC transporter
FUT84_RS06885	COG2226	methyltransferase
FUT84_RS06900	COG1120	ATPase activity
FUT84_RS06920	COG1132	(ABC) transporter
FUT84_RS06920	COG2375	cellular response to nickel ion
FUT84_RS06925	COG1132	(ABC) transporter
FUT84_RS07015	COG2226	methyltransferase
FUT84_RS07115	COG2195	Cleaves the N-terminal amino acid of tripeptides
FUT84_RS07120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FUT84_RS07125	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FUT84_RS07125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FUT84_RS07130	COG0739	heme binding
FUT84_RS07140	COG1132	(ABC) transporter
FUT84_RS07145	COG1132	(ABC) transporter
FUT84_RS07150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FUT84_RS07175	COG1187	pseudouridine synthase activity
FUT84_RS07205	COG1132	(ABC) transporter
FUT84_RS07210	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FUT84_RS07230	COG3706	GGDEF domain
FUT84_RS07245	COG1413	lyase activity
FUT84_RS07255	COG1012	belongs to the aldehyde dehydrogenase family
FUT84_RS07260	COG0673	inositol 2-dehydrogenase activity
FUT84_RS07265	COG1172	Belongs to the binding-protein-dependent transport system permease family
FUT84_RS07275	COG1879	ABC-type sugar transport system periplasmic component
FUT84_RS07325	COG2610	gluconate transmembrane transporter activity
FUT84_RS07330	COG1929	Belongs to the glycerate kinase type-1 family
FUT84_RS07340	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FUT84_RS07345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FUT84_RS07360	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FUT84_RS07415	COG0110	maltose O-acetyltransferase activity
FUT84_RS07425	COG3579	cysteine-type endopeptidase activity
FUT84_RS07445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FUT84_RS07465	COG3437	response regulator, receiver
FUT84_RS07465	COG2770	Histidine kinase
FUT84_RS07470	COG1214	PFAM Peptidase M22, glycoprotease
FUT84_RS07475	COG0802	atpase or kinase
FUT84_RS07480	COG0322	excinuclease ABC activity
FUT84_RS07510	COG2885	chlorophyll binding
FUT84_RS07525	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FUT84_RS07530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FUT84_RS07540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FUT84_RS07540	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FUT84_RS07565	COG0564	pseudouridine synthase activity
FUT84_RS07580	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FUT84_RS07590	COG0488	(ABC) transporter
FUT84_RS07590	COG0488	(ABC) transporter
FUT84_RS07600	COG1573	uracil-dna glycosylase
FUT84_RS07605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FUT84_RS07610	COG1086	Polysaccharide biosynthesis protein
FUT84_RS07620	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FUT84_RS07635	COG1136	(ABC) transporter
FUT84_RS07650	COG0552	protein localization to endoplasmic reticulum
FUT84_RS07680	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FUT84_RS07685	COG3457	Alanine racemase
FUT84_RS07690	COG0626	cystathionine gamma-synthase activity
FUT84_RS07735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FUT84_RS07755	COG1473	amidohydrolase
FUT84_RS07760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FUT84_RS07765	COG1121	(ABC) transporter
FUT84_RS07770	COG0803	Belongs to the bacterial solute-binding protein 9 family
FUT84_RS07775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FUT84_RS07780	COG2604	Protein of unknown function DUF115
FUT84_RS07790	COG1592	Rubrerythrin
FUT84_RS07815	COG0574	Belongs to the PEP-utilizing enzyme family
FUT84_RS07815	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FUT84_RS07820	COG1760	l-serine dehydratase
FUT84_RS07825	COG1760	l-serine dehydratase
FUT84_RS07830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FUT84_RS07855	COG2604	Protein of unknown function DUF115
FUT84_RS07860	COG0768	penicillin binding
FUT84_RS07870	COG1227	inorganic diphosphatase activity
FUT84_RS07870	COG0517	IMP dehydrogenase activity
FUT84_RS07885	COG0739	heme binding
FUT84_RS07910	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FUT84_RS07915	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FUT84_RS07920	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FUT84_RS07925	COG0739	heme binding
FUT84_RS07935	COG0351	phosphomethylpyrimidine kinase
FUT84_RS07940	COG0495	leucyl-tRNA aminoacylation
FUT84_RS07950	COG2089	acid synthase
FUT84_RS07965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FUT84_RS07970	COG2373	Large extracellular alpha-helical protein
FUT84_RS07975	COG4953	penicillin-binding protein 1C
FUT84_RS07980	COG1192	Involved in chromosome partitioning
FUT84_RS07985	COG1475	DNA binding
FUT84_RS07995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FUT84_RS08005	COG0741	lytic transglycosylase activity
FUT84_RS08005	COG1388	LysM domain
FUT84_RS08020	COG1040	competence protein
FUT84_RS08025	COG4209	transmembrane transport
FUT84_RS08055	COG2197	response regulator
FUT84_RS08070	COG0493	'glutamate synthase
FUT84_RS08075	COG0543	2 iron, 2 sulfur cluster binding
FUT84_RS08080	COG0740	serine-type endopeptidase activity
FUT84_RS08135	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FUT84_RS08180	COG0563	adenylate kinase activity
FUT84_RS08195	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FUT84_RS08200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FUT84_RS08205	COG0571	ribonuclease III activity
FUT84_RS08210	COG3700	Belongs to the class B bacterial acid phosphatase family
FUT84_RS08225	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FUT84_RS08230	COG3735	TraB family
FUT84_RS08235	COG0180	Tryptophanyl-tRNA synthetase
FUT84_RS08245	COG1131	(ABC) transporter
FUT84_RS08255	COG0574	Belongs to the PEP-utilizing enzyme family
FUT84_RS08255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FUT84_RS08270	COG2304	oxidoreductase activity
FUT84_RS08275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FUT84_RS08275	COG0426	domain, Protein
FUT84_RS08285	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FUT84_RS08300	COG1394	ATPase activity, coupled to movement of substances
FUT84_RS08310	COG0085	RNA polymerase activity
FUT84_RS08325	COG0081	regulation of translation
FUT84_RS08330	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FUT84_RS08335	COG0250	Participates in transcription elongation, termination and antitermination
FUT84_RS08340	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FUT84_RS08350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FUT84_RS08360	COG0716	FMN binding
FUT84_RS08375	COG1869	D-ribose catabolic process
FUT84_RS08380	COG1129	ABC transporter
FUT84_RS08385	COG1172	Belongs to the binding-protein-dependent transport system permease family
FUT84_RS08390	COG1879	ABC-type sugar transport system periplasmic component
FUT84_RS08690	COG2932	Transcriptional regulator
FUT84_RS08705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FUT84_RS08720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT84_RS08725	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FUT84_RS08730	COG3328	transposase activity
FUT84_RS08740	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FUT84_RS08745	COG1640	4-alpha-glucanotransferase
FUT84_RS08755	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FUT84_RS08765	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FUT84_RS08770	COG0706	membrane insertase activity
FUT84_RS08785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FUT84_RS08790	COG1305	Transglutaminase-like
FUT84_RS08800	COG0714	Associated with various cellular activities
FUT84_RS08805	COG0363	glucosamine-6-phosphate deaminase activity
FUT84_RS08820	COG3842	ATPase activity
FUT84_RS08825	COG1178	ABC-type Fe3 transport system permease component
FUT84_RS08840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FUT84_RS08860	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FUT84_RS08895	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
FUT84_RS08895	COG0028	Belongs to the TPP enzyme family
FUT84_RS08905	COG0673	inositol 2-dehydrogenase activity
FUT84_RS08950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FUT84_RS08955	COG2244	polysaccharide biosynthetic process
FUT84_RS09000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FUT84_RS09030	COG0251	oxidation-reduction process
FUT84_RS09035	COG1438	arginine binding
FUT84_RS09040	COG1475	DNA binding
FUT84_RS09045	COG0457	Tetratricopeptide repeat
FUT84_RS09055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FUT84_RS09060	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FUT84_RS09090	COG0542	response to heat
FUT84_RS09095	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FUT84_RS09105	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FUT84_RS09110	COG0584	glycerophosphoryl diester phosphodiesterase
FUT84_RS09115	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FUT84_RS09120	COG0762	integral membrane protein
FUT84_RS09125	COG0587	DNA-directed DNA polymerase activity
FUT84_RS09130	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FUT84_RS09145	COG0405	Gamma-glutamyltransferase
FUT84_RS09170	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FUT84_RS09185	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FUT84_RS09195	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FUT84_RS09200	COG2204	response regulator
FUT84_RS09220	COG0321	lipoyl(octanoyl) transferase activity
FUT84_RS09220	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FUT84_RS09240	COG0530	calcium, potassium:sodium antiporter activity
FUT84_RS09260	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FUT84_RS09285	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FUT84_RS09295	COG1115	amino acid carrier protein
FUT84_RS09310	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FUT84_RS09320	COG1692	metallophosphoesterase
FUT84_RS09325	COG1879	ABC-type sugar transport system periplasmic component
FUT84_RS09330	COG0037	tRNA processing
FUT84_RS09340	COG1309	transcriptional regulator
FUT84_RS09350	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FUT84_RS09360	COG1047	Peptidyl-prolyl cis-trans
FUT84_RS09370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FUT84_RS09375	COG3951	Flagellar rod assembly protein muramidase FlgJ
FUT84_RS09385	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FUT84_RS09400	COG1193	negative regulation of DNA recombination
FUT84_RS09405	COG1162	GTPase activity
FUT84_RS09420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FUT84_RS09445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FUT84_RS09445	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FUT84_RS09445	COG1013	pyruvate-flavodoxin oxidoreductase activity
FUT84_RS09445	COG0674	pyruvate-flavodoxin oxidoreductase activity
FUT84_RS09465	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FUT84_RS09465	COG1918	ferrous iron import across plasma membrane
FUT84_RS09515	COG2204	response regulator
FUT84_RS09520	COG3852	Histidine kinase
FUT84_RS09525	COG0470	DNA polymerase III
FUT84_RS09530	COG1286	toxin biosynthetic process
FUT84_RS09535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FUT84_RS09565	COG1692	metallophosphoesterase
FUT84_RS09575	COG0142	geranyltranstransferase activity
FUT84_RS09590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FUT84_RS09595	COG0205	6-phosphofructokinase activity
FUT84_RS09600	COG2801	Transposase and inactivated derivatives
FUT84_RS09625	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FUT84_RS09645	COG0017	Asparaginyl-tRNA synthetase
FUT84_RS09650	COG0840	transmembrane signaling receptor activity
FUT84_RS09670	COG0326	Molecular chaperone. Has ATPase activity
FUT84_RS09675	COG0517	IMP dehydrogenase activity
FUT84_RS09705	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FUT84_RS09720	COG0840	transmembrane signaling receptor activity
FUT84_RS09730	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FUT84_RS09750	COG2604	Protein of unknown function DUF115
FUT84_RS09780	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FUT84_RS09785	COG1418	mRNA catabolic process
FUT84_RS09800	COG1686	Belongs to the peptidase S11 family
FUT84_RS09810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FUT84_RS09860	COG3328	transposase activity
FUT84_RS09870	COG0514	ATP-dependent DNA helicase (RecQ)
FUT84_RS09875	COG0395	ABC-type sugar transport system, permease component
FUT84_RS09880	COG1175	transmembrane transport
FUT84_RS09910	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FUT84_RS09915	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT84_RS09915	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT84_RS09925	COG3037	sugar-specific permease SgaT UlaA
FUT84_RS09940	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FUT84_RS09950	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FUT84_RS09955	COG2911	Protein conserved in bacteria
FUT84_RS09960	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FUT84_RS09970	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FUT84_RS09975	COG0534	Mate efflux family protein
FUT84_RS10000	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FUT84_RS10010	COG4608	Belongs to the ABC transporter superfamily
FUT84_RS10015	COG0444	Belongs to the ABC transporter superfamily
FUT84_RS10020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FUT84_RS10025	COG0601	transmembrane transport
FUT84_RS10035	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FUT84_RS10040	COG0671	phosphoesterase, PA-phosphatase related
FUT84_RS10055	COG0497	DNA recombination
FUT84_RS10060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FUT84_RS10065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FUT84_RS10070	COG0835	chemotaxis
FUT84_RS10125	COG3876	Protein conserved in bacteria
FUT84_RS10130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FUT84_RS10135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FUT84_RS10140	COG0569	domain protein
FUT84_RS10155	COG0714	Associated with various cellular activities
FUT84_RS10170	COG1366	Belongs to the anti-sigma-factor antagonist family
FUT84_RS10190	COG0653	protein targeting
FUT84_RS10195	COG1132	(ABC) transporter
FUT84_RS10200	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FUT84_RS10205	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FUT84_RS10210	COG0626	cystathionine gamma-synthase activity
FUT84_RS10220	COG0674	pyruvate-flavodoxin oxidoreductase activity
FUT84_RS10220	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FUT84_RS10220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FUT84_RS10220	COG1013	pyruvate-flavodoxin oxidoreductase activity
FUT84_RS10225	COG2986	histidine ammonia-lyase
FUT84_RS10230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FUT84_RS10235	COG4209	transmembrane transport
FUT84_RS10240	COG0395	ABC-type sugar transport system, permease component
FUT84_RS10250	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FUT84_RS10255	COG1609	Transcriptional regulator
FUT84_RS10260	COG0142	geranyltranstransferase activity
FUT84_RS10270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FUT84_RS10280	COG3681	Belongs to the UPF0597 family
FUT84_RS10290	COG0561	phosphatase activity
FUT84_RS10300	COG0733	neurotransmitter:sodium symporter activity
FUT84_RS10305	COG0210	DNA helicase
FUT84_RS10350	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FUT84_RS10360	COG0335	large ribosomal subunit rRNA binding
FUT84_RS10365	COG0336	Belongs to the RNA methyltransferase TrmD family
FUT84_RS10370	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FUT84_RS10375	COG1837	Belongs to the UPF0109 family
FUT84_RS10380	COG0228	four-way junction DNA binding
FUT84_RS10415	COG0516	GMP reductase activity
FUT84_RS10415	COG0517	IMP dehydrogenase activity
FUT84_RS10420	COG1309	transcriptional regulator
FUT84_RS10425	COG1132	(ABC) transporter
FUT84_RS10425	COG2375	cellular response to nickel ion
FUT84_RS10430	COG1132	(ABC) transporter
FUT84_RS10455	COG1254	Belongs to the acylphosphatase family
FUT84_RS10465	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FUT84_RS10470	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FUT84_RS10495	COG1136	(ABC) transporter
FUT84_RS10515	COG4585	Histidine kinase
FUT84_RS10535	COG1131	(ABC) transporter
FUT84_RS10540	COG0513	Belongs to the DEAD box helicase family
FUT84_RS10545	COG0577	efflux transmembrane transporter activity
FUT84_RS10550	COG0577	efflux transmembrane transporter activity
FUT84_RS10555	COG1136	(ABC) transporter
FUT84_RS10575	COG0052	Belongs to the universal ribosomal protein uS2 family
FUT84_RS10580	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FUT84_RS10585	COG0233	cytoplasmic translational termination
FUT84_RS10590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FUT84_RS10595	COG4589	Belongs to the CDS family
FUT84_RS10600	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FUT84_RS10605	COG0750	zinc metalloprotease
FUT84_RS10630	COG0681	Belongs to the peptidase S26 family
FUT84_RS10635	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FUT84_RS10640	COG0616	signal peptide processing
FUT84_RS10665	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FUT84_RS10680	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FUT84_RS10680	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FUT84_RS10685	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FUT84_RS10690	COG0617	tRNA 3'-terminal CCA addition
FUT84_RS10700	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FUT84_RS10715	COG0629	single-stranded DNA binding
FUT84_RS10720	COG0205	6-phosphofructokinase activity
FUT84_RS10730	COG0494	nUDIX hydrolase
FUT84_RS10750	COG0488	(ABC) transporter
FUT84_RS10775	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FUT84_RS10775	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FUT84_RS10780	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FUT84_RS10795	COG0395	ABC-type sugar transport system, permease component
FUT84_RS10810	COG1175	transmembrane transport
FUT84_RS10815	COG0395	ABC-type sugar transport system, permease component
FUT84_RS10845	COG0254	rRNA binding
FUT84_RS10850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FUT84_RS10855	COG1058	Belongs to the CinA family
FUT84_RS10855	COG1546	Belongs to the CinA family
FUT84_RS10865	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FUT84_RS10875	COG0776	regulation of translation
FUT84_RS10880	COG0268	Binds directly to 16S ribosomal RNA
FUT84_RS10885	COG2357	RelA SpoT domain protein
FUT84_RS10900	COG0860	N-Acetylmuramoyl-L-alanine amidase
FUT84_RS10920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FUT84_RS10925	COG3118	belongs to the thioredoxin family
FUT84_RS10930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FUT84_RS10935	COG0084	hydrolase, TatD family'
FUT84_RS10945	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FUT84_RS10980	COG0668	transmembrane transport
FUT84_RS10985	COG0617	tRNA 3'-terminal CCA addition
FUT84_RS10995	COG1172	Belongs to the binding-protein-dependent transport system permease family
FUT84_RS11000	COG1129	ABC transporter
FUT84_RS11020	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FUT84_RS11030	COG1131	(ABC) transporter
FUT84_RS11050	COG0513	Belongs to the DEAD box helicase family
FUT84_RS11060	COG0432	Pfam Uncharacterised protein family UPF0047
FUT84_RS11100	COG1228	amidohydrolase
FUT84_RS11105	COG0673	inositol 2-dehydrogenase activity
FUT84_RS11110	COG0191	fructose-bisphosphate aldolase activity
FUT84_RS11115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FUT84_RS11125	COG1349	DNA-binding transcription factor activity
FUT84_RS11135	COG0523	cobalamin synthesis protein
FUT84_RS11150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FUT84_RS11150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FUT84_RS11155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FUT84_RS11165	COG0601	transmembrane transport
FUT84_RS11175	COG0444	Belongs to the ABC transporter superfamily
FUT84_RS11180	COG4608	Belongs to the ABC transporter superfamily
FUT84_RS11185	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FUT84_RS11195	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FUT84_RS11210	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FUT84_RS11215	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FUT84_RS11220	COG0460	homoserine dehydrogenase
FUT84_RS11225	COG2239	Acts as a magnesium transporter
FUT84_RS11260	COG1272	protein, Hemolysin III
FUT84_RS11275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FUT84_RS11285	COG0295	cytidine deaminase activity
FUT84_RS11295	COG0739	heme binding
FUT84_RS11300	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FUT84_RS11300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FUT84_RS11310	COG0318	PFAM AMP-dependent synthetase and ligase
FUT84_RS11315	COG1388	LysM domain
FUT84_RS11315	COG0791	NLP P60 protein
FUT84_RS11325	COG1979	alcohol dehydrogenase
FUT84_RS11335	COG0724	RNA recognition motif
FUT84_RS11345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FUT84_RS11350	COG3842	ATPase activity
FUT84_RS11355	COG1176	ABC-type spermidine putrescine transport system, permease component I
FUT84_RS11360	COG1177	transmembrane transport
FUT84_RS11370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FUT84_RS11375	COG1509	lysine 2,3-aminomutase activity
FUT84_RS11395	COG0138	bifunctional purine biosynthesis protein purh
FUT84_RS11400	COG0151	Belongs to the GarS family
FUT84_RS11405	COG2339	peptidase activity
FUT84_RS11410	COG0840	transmembrane signaling receptor activity
FUT84_RS11430	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FUT84_RS11445	COG4211	Belongs to the binding-protein-dependent transport system permease family
FUT84_RS11450	COG1129	ABC transporter
FUT84_RS11455	COG1879	ABC-type sugar transport system periplasmic component
FUT84_RS11460	COG0803	Belongs to the bacterial solute-binding protein 9 family
FUT84_RS11465	COG1121	(ABC) transporter
FUT84_RS11470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FUT84_RS11475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FUT84_RS11480	COG1321	iron dependent repressor
FUT84_RS11485	COG1022	Amp-dependent synthetase and ligase
FUT84_RS11490	COG2890	protein-(glutamine-N5) methyltransferase activity
FUT84_RS11495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FUT84_RS11520	COG0658	competence protein
FUT84_RS11520	COG2333	competence protein COMEC
FUT84_RS11545	COG0285	dihydrofolate synthase activity
FUT84_RS11550	COG2832	Protein of unknown function (DUF454)
FUT84_RS11555	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FUT84_RS11565	COG1269	ATP hydrolysis coupled proton transport
FUT84_RS11570	COG1394	ATPase activity, coupled to movement of substances
FUT84_RS11575	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FUT84_RS11580	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FUT84_RS11590	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
FUT84_RS11670	COG0297	glycogen (starch) synthase activity
FUT84_RS11720	COG2738	Putative neutral zinc metallopeptidase
FUT84_RS11750	COG2255	four-way junction helicase activity
FUT84_RS11755	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FUT84_RS11770	COG1362	aminopeptidase activity
FUT84_RS11780	COG1570	exodeoxyribonuclease VII activity
FUT84_RS11810	COG4750	Nucleotidyl transferase
FUT84_RS11815	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FUT84_RS11835	COG0840	transmembrane signaling receptor activity
FUT84_RS11860	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FUT84_RS11865	COG1214	PFAM Peptidase M22, glycoprotease
FUT84_RS11865	COG0456	acetyltransferase
FUT84_RS11870	COG1811	Na channel or pump
FUT84_RS11885	COG2059	Chromate
FUT84_RS11910	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FUT84_RS11915	COG1012	belongs to the aldehyde dehydrogenase family
FUT84_RS11925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FUT84_RS11950	COG1609	Transcriptional regulator
FUT84_RS11965	COG0632	four-way junction helicase activity
FUT84_RS11975	COG0457	Tetratricopeptide repeat
FUT84_RS11980	COG0785	Cytochrome C biogenesis protein
FUT84_RS11985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FUT84_RS12010	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT84_RS12015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FUT84_RS12015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT84_RS12015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FUT84_RS12020	COG1105	Belongs to the carbohydrate kinase PfkB family
FUT84_RS12025	COG1349	DNA-binding transcription factor activity
FUT84_RS12030	COG0450	alkyl hydroperoxide reductase
FUT84_RS12050	COG1472	Belongs to the glycosyl hydrolase 3 family
FUT84_RS12055	COG0492	ferredoxin-NADP+ reductase activity
FUT84_RS12075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FUT84_RS12080	COG0444	Belongs to the ABC transporter superfamily
FUT84_RS12085	COG4608	Belongs to the ABC transporter superfamily
FUT84_RS12090	COG1132	(ABC) transporter
FUT84_RS12095	COG1132	(ABC) transporter
FUT84_RS12100	COG1132	(ABC) transporter
FUT84_RS12105	COG1132	(ABC) transporter
FUT84_RS12115	COG1181	Belongs to the D-alanine--D-alanine ligase family
FUT84_RS12150	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FUT84_RS12165	COG2801	Transposase and inactivated derivatives
FUT84_RS12190	COG0584	glycerophosphoryl diester phosphodiesterase
FUT84_RS12195	COG3958	Transketolase
FUT84_RS12200	COG3959	Transketolase, thiamine diphosphate binding domain
FUT84_RS12220	COG1122	ATPase activity
FUT84_RS12225	COG1268	BioY protein
FUT84_RS12230	COG0012	GTP binding
FUT84_RS12235	COG0205	6-phosphofructokinase activity
FUT84_RS12265	COG1477	protein flavinylation
FUT84_RS12315	COG5433	transposase activity
FUT84_RS12320	COG0840	transmembrane signaling receptor activity
FUT84_RS12325	COG1074	ATP-dependent DNA helicase activity
FUT84_RS12330	COG2887	Belongs to the helicase family. UvrD subfamily
FUT84_RS12340	COG2801	Transposase and inactivated derivatives
FUT84_RS12350	COG2801	Transposase and inactivated derivatives
FUT84_RS12360	COG2801	Transposase and inactivated derivatives
FUT84_RS12370	COG2201	protein-glutamate methylesterase activity
FUT84_RS12390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FUT84_RS12395	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FUT84_RS12400	COG0215	cysteine-tRNA ligase activity
FUT84_RS12415	COG1305	Transglutaminase-like
FUT84_RS12420	COG0528	UMP kinase activity
FUT84_RS12430	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FUT84_RS12435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FUT84_RS12440	COG5002	protein histidine kinase activity
FUT84_RS12440	COG2205	protein histidine kinase activity
FUT84_RS12440	COG0784	Response regulator, receiver
FUT84_RS12445	COG0457	Tetratricopeptide repeat
FUT84_RS12450	COG0280	phosphate acetyltransferase
FUT84_RS12460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FUT84_RS12465	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FUT84_RS12485	COG1983	PspC domain protein
FUT84_RS12515	COG1136	(ABC) transporter
FUT84_RS12520	COG4475	Protein of unknown function (DUF436)
FUT84_RS12525	COG2252	PERMEase
FUT84_RS12545	COG0395	ABC-type sugar transport system, permease component
FUT84_RS12555	COG4209	transmembrane transport
FUT84_RS12565	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FUT84_RS12570	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FUT84_RS12575	COG1924	4 iron, 4 sulfur cluster binding
FUT84_RS12580	COG0786	glutamate:sodium symporter activity
FUT84_RS12585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FUT84_RS12590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FUT84_RS12595	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FUT84_RS12600	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FUT84_RS12605	COG4770	biotin carboxylase activity
FUT84_RS12615	COG0786	glutamate:sodium symporter activity
FUT84_RS12620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FUT84_RS12640	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FUT84_RS12655	COG1744	ABC transporter substrate-binding protein PnrA-like
FUT84_RS12660	COG3845	ABC transporter
FUT84_RS12665	COG4603	Belongs to the binding-protein-dependent transport system permease family
FUT84_RS12670	COG1079	Belongs to the binding-protein-dependent transport system permease family
FUT84_RS12680	COG1346	cytolysis
FUT84_RS12700	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FUT84_RS12720	COG0191	fructose-bisphosphate aldolase activity
FUT84_RS12745	COG4166	transmembrane transport
FUT84_RS12760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FUT84_RS12780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FUT84_RS12785	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FUT84_RS12790	COG1862	Preprotein translocase
FUT84_RS12795	COG1639	'signal transduction protein
FUT84_RS12805	COG4115	mRNA cleavage
FUT84_RS12820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FUT84_RS12830	COG0504	CTP synthase activity
FUT84_RS12835	COG1757	Na H antiporter
FUT84_RS12850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FUT84_RS12860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FUT84_RS12865	COG0765	amino acid transport
FUT84_RS12870	COG1126	abc transporter atp-binding protein
FUT84_RS12885	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FUT84_RS12895	COG1175	transmembrane transport
FUT84_RS12905	COG0330	HflC and HflK could
FUT84_RS12910	COG0330	HflC and HflK could
FUT84_RS12930	COG1785	Belongs to the alkaline phosphatase family
FUT84_RS12955	COG1136	(ABC) transporter
FUT84_RS12975	COG1132	(ABC) transporter
FUT84_RS13010	COG0525	valine-tRNA ligase activity
FUT84_RS13025	COG0737	Belongs to the 5'-nucleotidase family
FUT84_RS13035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FUT84_RS13040	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FUT84_RS13050	COG2095	MarC family integral membrane protein
FUT84_RS13055	COG2801	Transposase and inactivated derivatives
FUT84_RS13070	COG1070	Carbohydrate kinase
FUT84_RS13080	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FUT84_RS13085	COG1739	Uncharacterized protein family UPF0029
FUT84_RS13100	COG0756	dUTP diphosphatase activity
FUT84_RS13105	COG1185	polyribonucleotide nucleotidyltransferase activity
FUT84_RS13115	COG0196	riboflavin kinase activity
FUT84_RS13125	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FUT84_RS13135	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FUT84_RS13145	COG0779	Required for maturation of 30S ribosomal subunits
FUT84_RS13150	COG0343	queuine tRNA-ribosyltransferase activity
FUT84_RS13160	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FUT84_RS13190	COG1368	sulfuric ester hydrolase activity
FUT84_RS13195	COG1368	sulfuric ester hydrolase activity
FUT84_RS13215	COG1802	Transcriptional regulator
FUT84_RS13230	COG0656	L-ascorbic acid biosynthetic process
FUT84_RS13240	COG3842	ATPase activity
FUT84_RS13245	COG0737	Belongs to the 5'-nucleotidase family
FUT84_RS13270	COG1067	ATP-dependent peptidase activity
FUT84_RS13305	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FUT84_RS13305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FUT84_RS13320	COG1104	cysteine desulfurase activity
FUT84_RS13325	COG0778	Nitroreductase
FUT84_RS13335	COG2801	Transposase and inactivated derivatives
FUT84_RS13365	COG0733	neurotransmitter:sodium symporter activity
FUT84_RS13370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FUT84_RS13380	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FUT84_RS13400	COG2116	formate transmembrane transporter activity
FUT84_RS13405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FUT84_RS13430	COG4536	flavin adenine dinucleotide binding
FUT84_RS13435	COG1253	flavin adenine dinucleotide binding
FUT84_RS13440	COG0800	Aldolase
FUT84_RS13460	COG3706	GGDEF domain
FUT84_RS13465	COG3706	GGDEF domain
FUT84_RS13480	COG1653	transport
FUT84_RS13490	COG0395	ABC-type sugar transport system, permease component
FUT84_RS13520	COG2801	Transposase and inactivated derivatives
FUT84_RS13550	COG2801	Transposase and inactivated derivatives
FUT84_RS13565	COG0556	nucleotide-excision repair
FUT84_RS13660	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FUT84_RS13805	COG0653	protein targeting
FUT84_RS13855	COG1879	ABC-type sugar transport system periplasmic component
FUT84_RS13860	COG1129	ABC transporter
FUT84_RS13865	COG1172	Belongs to the binding-protein-dependent transport system permease family
FUT84_RS13870	COG1172	Belongs to the binding-protein-dependent transport system permease family
FUT84_RS13910	COG0719	Fe-S assembly protein
FUT84_RS13915	COG0719	Fe-S assembly protein
FUT84_RS13920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FUT84_RS13925	COG0822	iron-sulfur transferase activity
FUT84_RS13945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FUT84_RS13950	COG0670	Belongs to the BI1 family
FUT84_RS13960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FUT84_RS13970	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FUT84_RS13980	COG1129	ABC transporter
FUT84_RS13985	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FUT84_RS13995	COG0446	pyridine nucleotide-disulphide oxidoreductase
FUT84_RS14020	COG0116	Belongs to the methyltransferase superfamily
FUT84_RS14025	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FUT84_RS14030	COG1687	branched-chain amino acid