locus-tag	class	description
FUT83_RS00010	COG0592	DNA-directed DNA polymerase activity
FUT83_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FUT83_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
FUT83_RS00035	COG0733	neurotransmitter:sodium symporter activity
FUT83_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FUT83_RS00045	COG0765	amino acid transport
FUT83_RS00050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FUT83_RS00060	COG1126	abc transporter atp-binding protein
FUT83_RS00070	COG1924	4 iron, 4 sulfur cluster binding
FUT83_RS00080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FUT83_RS00085	COG0564	pseudouridine synthase activity
FUT83_RS00090	COG2195	Cleaves the N-terminal amino acid of tripeptides
FUT83_RS00095	COG4555	ABC transporter
FUT83_RS00125	COG0731	radical SAM domain protein
FUT83_RS00135	COG0423	glycine-tRNA ligase activity
FUT83_RS00140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FUT83_RS00170	COG1349	DNA-binding transcription factor activity
FUT83_RS00185	COG2211	Major facilitator Superfamily
FUT83_RS00190	COG3250	beta-galactosidase activity
FUT83_RS00195	COG1904	glucuronate isomerase
FUT83_RS00215	COG0246	Mannitol dehydrogenase
FUT83_RS00220	COG1312	Catalyzes the dehydration of D-mannonate
FUT83_RS00230	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FUT83_RS00235	COG0628	permease
FUT83_RS00250	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FUT83_RS00265	COG0442	prolyl-tRNA aminoacylation
FUT83_RS00270	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FUT83_RS00280	COG1454	alcohol dehydrogenase
FUT83_RS00280	COG1012	belongs to the aldehyde dehydrogenase family
FUT83_RS00300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FUT83_RS00315	COG1747	RNA polymerase binding
FUT83_RS00315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FUT83_RS00325	COG2183	response to ionizing radiation
FUT83_RS00360	COG0018	arginyl-trna synthetase
FUT83_RS00375	COG0840	transmembrane signaling receptor activity
FUT83_RS00380	COG0420	3'-5' exonuclease activity
FUT83_RS00385	COG0419	ATPase involved in DNA repair
FUT83_RS00390	COG2801	Transposase and inactivated derivatives
FUT83_RS00400	COG2801	Transposase and inactivated derivatives
FUT83_RS00410	COG0840	transmembrane signaling receptor activity
FUT83_RS00540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FUT83_RS00650	COG1983	PspC domain protein
FUT83_RS00675	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
FUT83_RS00685	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FUT83_RS00690	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FUT83_RS00695	COG1394	ATPase activity, coupled to movement of substances
FUT83_RS00700	COG1269	ATP hydrolysis coupled proton transport
FUT83_RS00710	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FUT83_RS00715	COG2832	Protein of unknown function (DUF454)
FUT83_RS00720	COG0285	dihydrofolate synthase activity
FUT83_RS00745	COG2333	competence protein COMEC
FUT83_RS00745	COG0658	competence protein
FUT83_RS00760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FUT83_RS00760	COG1263	PTS System
FUT83_RS00765	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FUT83_RS00770	COG0708	Exodeoxyribonuclease III
FUT83_RS00780	COG4443	Transcriptional Coactivator p15 (PC4)
FUT83_RS00785	COG0328	RNA-DNA hybrid ribonuclease activity
FUT83_RS00790	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FUT83_RS00795	COG4988	ABC transporter
FUT83_RS00800	COG1294	oxidase, subunit
FUT83_RS00805	COG1271	oxidase subunit
FUT83_RS00880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FUT83_RS00885	COG0728	peptidoglycan biosynthetic process
FUT83_RS00900	COG0579	oxidoreductase
FUT83_RS00905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FUT83_RS00910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FUT83_RS00920	COG0124	histidyl-tRNA synthetase
FUT83_RS00925	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FUT83_RS00930	COG0154	amidase activity
FUT83_RS00945	COG1028	Short-chain dehydrogenase reductase Sdr
FUT83_RS00950	COG1131	(ABC) transporter
FUT83_RS00975	COG0701	Predicted permease
FUT83_RS00985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FUT83_RS01020	COG1137	ATPase activity
FUT83_RS01030	COG1132	(ABC) transporter
FUT83_RS01035	COG4988	ABC transporter
FUT83_RS01045	COG3142	Participates in the control of copper homeostasis
FUT83_RS01050	COG1335	isochorismatase
FUT83_RS01080	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FUT83_RS01085	COG1012	belongs to the aldehyde dehydrogenase family
FUT83_RS01095	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FUT83_RS01120	COG1609	Transcriptional regulator
FUT83_RS01135	COG0632	four-way junction helicase activity
FUT83_RS01145	COG0457	Tetratricopeptide repeat
FUT83_RS01150	COG0785	Cytochrome C biogenesis protein
FUT83_RS01155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FUT83_RS01175	COG0840	transmembrane signaling receptor activity
FUT83_RS01180	COG1053	succinate dehydrogenase
FUT83_RS01180	COG3976	FMN-binding domain protein
FUT83_RS01180	COG0431	NADPH-dependent FMN reductase
FUT83_RS01195	COG0205	6-phosphofructokinase activity
FUT83_RS01225	COG1477	protein flavinylation
FUT83_RS01275	COG5433	transposase activity
FUT83_RS01295	COG1074	ATP-dependent DNA helicase activity
FUT83_RS01300	COG2887	Belongs to the helicase family. UvrD subfamily
FUT83_RS01310	COG2801	Transposase and inactivated derivatives
FUT83_RS01320	COG2801	Transposase and inactivated derivatives
FUT83_RS01330	COG2201	protein-glutamate methylesterase activity
FUT83_RS01350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FUT83_RS01355	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FUT83_RS01360	COG0215	cysteine-tRNA ligase activity
FUT83_RS01375	COG1305	Transglutaminase-like
FUT83_RS01380	COG0528	UMP kinase activity
FUT83_RS01390	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FUT83_RS01395	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FUT83_RS01405	COG2205	protein histidine kinase activity
FUT83_RS01405	COG2198	Histidine kinase
FUT83_RS01405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FUT83_RS01405	COG0784	Response regulator, receiver
FUT83_RS01410	COG0457	Tetratricopeptide repeat
FUT83_RS01415	COG0280	phosphate acetyltransferase
FUT83_RS01425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FUT83_RS01430	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FUT83_RS01435	COG0516	GMP reductase activity
FUT83_RS01435	COG0517	IMP dehydrogenase activity
FUT83_RS01440	COG1309	transcriptional regulator
FUT83_RS01445	COG1132	(ABC) transporter
FUT83_RS01445	COG2375	cellular response to nickel ion
FUT83_RS01450	COG1132	(ABC) transporter
FUT83_RS01465	COG2885	chlorophyll binding
FUT83_RS01500	COG0481	GTPase activity
FUT83_RS01505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FUT83_RS01510	COG0457	Tetratricopeptide repeat
FUT83_RS01520	COG0037	tRNA processing
FUT83_RS01525	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FUT83_RS01535	COG2088	sporulation resulting in formation of a cellular spore
FUT83_RS01540	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FUT83_RS01560	COG1136	(ABC) transporter
FUT83_RS01590	COG1785	Belongs to the alkaline phosphatase family
FUT83_RS01615	COG0330	HflC and HflK could
FUT83_RS01625	COG1175	transmembrane transport
FUT83_RS01635	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
FUT83_RS01650	COG1126	abc transporter atp-binding protein
FUT83_RS01655	COG0765	amino acid transport
FUT83_RS01660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FUT83_RS01670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FUT83_RS01685	COG1757	Na H antiporter
FUT83_RS01690	COG0504	CTP synthase activity
FUT83_RS01700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FUT83_RS01715	COG4115	mRNA cleavage
FUT83_RS01725	COG1639	'signal transduction protein
FUT83_RS01730	COG1862	Preprotein translocase
FUT83_RS01735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FUT83_RS01740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FUT83_RS01760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FUT83_RS01775	COG4166	transmembrane transport
FUT83_RS01800	COG0191	fructose-bisphosphate aldolase activity
FUT83_RS01820	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FUT83_RS01840	COG1346	cytolysis
FUT83_RS01850	COG1079	Belongs to the binding-protein-dependent transport system permease family
FUT83_RS01855	COG4603	Belongs to the binding-protein-dependent transport system permease family
FUT83_RS01860	COG3845	ABC transporter
FUT83_RS01865	COG1744	ABC transporter substrate-binding protein PnrA-like
FUT83_RS01880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FUT83_RS01900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FUT83_RS01905	COG0786	glutamate:sodium symporter activity
FUT83_RS01915	COG4770	biotin carboxylase activity
FUT83_RS01920	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FUT83_RS01925	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FUT83_RS01930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FUT83_RS01935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FUT83_RS01940	COG0786	glutamate:sodium symporter activity
FUT83_RS01945	COG1924	4 iron, 4 sulfur cluster binding
FUT83_RS01950	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FUT83_RS01955	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
FUT83_RS01965	COG4209	transmembrane transport
FUT83_RS01975	COG0395	ABC-type sugar transport system, permease component
FUT83_RS01995	COG2252	PERMEase
FUT83_RS02025	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FUT83_RS02030	COG0737	Belongs to the 5'-nucleotidase family
FUT83_RS02165	COG0840	transmembrane signaling receptor activity
FUT83_RS02170	COG2339	peptidase activity
FUT83_RS02175	COG0151	Belongs to the GarS family
FUT83_RS02180	COG0138	bifunctional purine biosynthesis protein purh
FUT83_RS02200	COG1509	lysine 2,3-aminomutase activity
FUT83_RS02205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FUT83_RS02215	COG1177	transmembrane transport
FUT83_RS02220	COG1176	ABC-type spermidine putrescine transport system, permease component I
FUT83_RS02225	COG3842	ATPase activity
FUT83_RS02435	COG2932	Transcriptional regulator
FUT83_RS02515	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FUT83_RS02635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FUT83_RS02740	COG1253	flavin adenine dinucleotide binding
FUT83_RS02745	COG4536	flavin adenine dinucleotide binding
FUT83_RS02765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FUT83_RS02770	COG0840	transmembrane signaling receptor activity
FUT83_RS02790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FUT83_RS02795	COG2116	formate transmembrane transporter activity
FUT83_RS02815	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FUT83_RS02825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FUT83_RS02830	COG0733	neurotransmitter:sodium symporter activity
FUT83_RS02860	COG2801	Transposase and inactivated derivatives
FUT83_RS02870	COG0778	Nitroreductase
FUT83_RS02875	COG1104	cysteine desulfurase activity
FUT83_RS02885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FUT83_RS02885	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FUT83_RS02925	COG1067	ATP-dependent peptidase activity
FUT83_RS02950	COG0737	Belongs to the 5'-nucleotidase family
FUT83_RS02955	COG3842	ATPase activity
FUT83_RS02965	COG0656	L-ascorbic acid biosynthetic process
FUT83_RS02980	COG1802	Transcriptional regulator
FUT83_RS03000	COG1368	sulfuric ester hydrolase activity
FUT83_RS03005	COG1368	sulfuric ester hydrolase activity
FUT83_RS03245	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FUT83_RS03255	COG0343	queuine tRNA-ribosyltransferase activity
FUT83_RS03265	COG1253	flavin adenine dinucleotide binding
FUT83_RS03280	COG0737	Belongs to the 5'-nucleotidase family
FUT83_RS03290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FUT83_RS03295	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FUT83_RS03300	COG3437	response regulator, receiver
FUT83_RS03305	COG1671	Belongs to the UPF0178 family
FUT83_RS03315	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FUT83_RS03325	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FUT83_RS03340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FUT83_RS03345	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FUT83_RS03360	COG0237	dephospho-CoA kinase activity
FUT83_RS03365	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FUT83_RS03370	COG0710	3-dehydroquinate dehydratase activity
FUT83_RS03370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FUT83_RS03385	COG2095	MarC family integral membrane protein
FUT83_RS03390	COG2801	Transposase and inactivated derivatives
FUT83_RS03420	COG1175	transmembrane transport
FUT83_RS03425	COG0395	ABC-type sugar transport system, permease component
FUT83_RS03435	COG1739	Uncharacterized protein family UPF0029
FUT83_RS03450	COG0756	dUTP diphosphatase activity
FUT83_RS03455	COG1185	polyribonucleotide nucleotidyltransferase activity
FUT83_RS03465	COG0196	riboflavin kinase activity
FUT83_RS03475	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FUT83_RS03485	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FUT83_RS03495	COG0779	Required for maturation of 30S ribosomal subunits
FUT83_RS03500	COG0525	valine-tRNA ligase activity
FUT83_RS03520	COG1132	(ABC) transporter
FUT83_RS03525	COG1132	(ABC) transporter
FUT83_RS03545	COG0800	Aldolase
FUT83_RS03565	COG3706	GGDEF domain
FUT83_RS03570	COG3706	GGDEF domain
FUT83_RS03585	COG1653	transport
FUT83_RS03595	COG0395	ABC-type sugar transport system, permease component
FUT83_RS03620	COG0556	nucleotide-excision repair
FUT83_RS03640	COG1102	Psort location Cytoplasmic, score
FUT83_RS03740	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FUT83_RS03885	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FUT83_RS03900	COG4211	Belongs to the binding-protein-dependent transport system permease family
FUT83_RS03905	COG1129	ABC transporter
FUT83_RS03910	COG1879	ABC-type sugar transport system periplasmic component
FUT83_RS03930	COG5377	YqaJ viral recombinase family
FUT83_RS03950	COG3723	Recombinational DNA repair protein, rece pathway
FUT83_RS03975	COG0629	single-stranded DNA binding
FUT83_RS04005	COG3328	transposase activity
FUT83_RS04015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FUT83_RS04025	COG0724	RNA recognition motif
FUT83_RS04035	COG1979	alcohol dehydrogenase
FUT83_RS04045	COG1388	LysM domain
FUT83_RS04045	COG0791	NLP P60 protein
FUT83_RS04050	COG0318	PFAM AMP-dependent synthetase and ligase
FUT83_RS04060	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FUT83_RS04060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FUT83_RS04065	COG0739	heme binding
FUT83_RS04075	COG0295	cytidine deaminase activity
FUT83_RS04085	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FUT83_RS04100	COG1272	protein, Hemolysin III
FUT83_RS04130	COG2239	Acts as a magnesium transporter
FUT83_RS04135	COG0460	homoserine dehydrogenase
FUT83_RS04140	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FUT83_RS04145	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FUT83_RS04160	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FUT83_RS04170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FUT83_RS04175	COG4608	Belongs to the ABC transporter superfamily
FUT83_RS04180	COG0444	Belongs to the ABC transporter superfamily
FUT83_RS04190	COG0601	transmembrane transport
FUT83_RS04200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FUT83_RS04205	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FUT83_RS04205	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FUT83_RS04220	COG0523	cobalamin synthesis protein
FUT83_RS04230	COG1349	DNA-binding transcription factor activity
FUT83_RS04240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FUT83_RS04245	COG0191	fructose-bisphosphate aldolase activity
FUT83_RS04250	COG0673	inositol 2-dehydrogenase activity
FUT83_RS04255	COG1228	amidohydrolase
FUT83_RS04290	COG0432	Pfam Uncharacterised protein family UPF0047
FUT83_RS04300	COG0513	Belongs to the DEAD box helicase family
FUT83_RS04320	COG1131	(ABC) transporter
FUT83_RS04330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FUT83_RS04345	COG1129	ABC transporter
FUT83_RS04350	COG1172	Belongs to the binding-protein-dependent transport system permease family
FUT83_RS04365	COG0626	cystathionine gamma-synthase activity
FUT83_RS04375	COG1175	transmembrane transport
FUT83_RS04395	COG0668	transmembrane transport
FUT83_RS04400	COG0617	tRNA 3'-terminal CCA addition
FUT83_RS04420	COG0433	COG0433 Predicted ATPase
FUT83_RS04430	COG2801	Transposase and inactivated derivatives
FUT83_RS04465	COG0840	transmembrane signaling receptor activity
FUT83_RS04475	COG0778	Nitroreductase
FUT83_RS04515	COG1744	ABC transporter substrate-binding protein PnrA-like
FUT83_RS04520	COG3845	ABC transporter
FUT83_RS04525	COG4603	Belongs to the binding-protein-dependent transport system permease family
FUT83_RS04530	COG1079	Belongs to the binding-protein-dependent transport system permease family
FUT83_RS04535	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FUT83_RS04600	COG0049	tRNA binding
FUT83_RS04605	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FUT83_RS04610	COG1053	succinate dehydrogenase
FUT83_RS04615	COG2081	HI0933 family
FUT83_RS04620	COG0187	DNA topoisomerase II activity
FUT83_RS04725	COG1285	pathogenesis
FUT83_RS04730	COG3330	Domain of unknown function (DUF4912)
FUT83_RS04745	COG0455	bacterial-type flagellum organization
FUT83_RS04755	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FUT83_RS04775	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FUT83_RS04780	COG0740	serine-type endopeptidase activity
FUT83_RS04785	COG0544	peptidyl-prolyl cis-trans isomerase activity
FUT83_RS04830	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FUT83_RS04830	COG3116	cell division
FUT83_RS04835	COG0084	hydrolase, TatD family'
FUT83_RS04860	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FUT83_RS04870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FUT83_RS04880	COG0360	Binds together with S18 to 16S ribosomal RNA
FUT83_RS04885	COG0629	single-stranded DNA binding
FUT83_RS04890	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FUT83_RS04895	COG0359	binds to the 23S rRNA
FUT83_RS04900	COG0305	Participates in initiation and elongation during chromosome replication
FUT83_RS04945	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FUT83_RS04950	COG1160	GTP binding
FUT83_RS04985	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FUT83_RS04985	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FUT83_RS04985	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT83_RS05010	COG0484	heat shock protein binding
FUT83_RS05020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FUT83_RS05025	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FUT83_RS05030	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FUT83_RS05050	COG1269	ATP hydrolysis coupled proton transport
FUT83_RS05055	COG1527	subunit (C
FUT83_RS05065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FUT83_RS05065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FUT83_RS05065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT83_RS05070	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FUT83_RS05085	COG2313	pseudouridylate synthase activity
FUT83_RS05090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FUT83_RS05095	COG2001	Belongs to the MraZ family
FUT83_RS05100	COG0275	rRNA processing
FUT83_RS05115	COG0772	Belongs to the SEDS family
FUT83_RS05120	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FUT83_RS05130	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FUT83_RS05135	COG4974	Belongs to the 'phage' integrase family
FUT83_RS05145	COG0758	DNA mediated transformation
FUT83_RS05150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FUT83_RS05150	COG0551	DNA topoisomerase type I activity
FUT83_RS05155	COG4974	Belongs to the 'phage' integrase family
FUT83_RS05160	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FUT83_RS05165	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FUT83_RS05175	COG1815	bacterial-type flagellum-dependent cell motility
FUT83_RS05190	COG1766	The M ring may be actively involved in energy transduction
FUT83_RS05200	COG1317	bacterial-type flagellum organization
FUT83_RS05205	COG1157	protein secretion by the type III secretion system
FUT83_RS05220	COG0019	diaminopimelate decarboxylase activity
FUT83_RS05235	COG0438	transferase activity, transferring glycosyl groups
FUT83_RS05260	COG2186	Transcriptional regulator
FUT83_RS05295	COG1490	D-aminoacyl-tRNA deacylase activity
FUT83_RS05300	COG0193	aminoacyl-tRNA hydrolase activity
FUT83_RS05320	COG1473	amidohydrolase
FUT83_RS05335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FUT83_RS05345	COG0545	Peptidyl-prolyl cis-trans isomerase
FUT83_RS05365	COG2217	Heavy metal translocating P-type atpase
FUT83_RS05370	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FUT83_RS05375	COG0813	purine-nucleoside phosphorylase activity
FUT83_RS05380	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FUT83_RS05395	COG0840	transmembrane signaling receptor activity
FUT83_RS05435	COG2801	Transposase and inactivated derivatives
FUT83_RS05440	COG0205	6-phosphofructokinase activity
FUT83_RS05445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FUT83_RS05460	COG0142	geranyltranstransferase activity
FUT83_RS05470	COG1692	metallophosphoesterase
FUT83_RS05495	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FUT83_RS05500	COG1286	toxin biosynthetic process
FUT83_RS05505	COG0470	DNA polymerase III
FUT83_RS05510	COG3852	Histidine kinase
FUT83_RS05515	COG2204	response regulator
FUT83_RS05565	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FUT83_RS05565	COG1918	ferrous iron import across plasma membrane
FUT83_RS05585	COG0674	pyruvate-flavodoxin oxidoreductase activity
FUT83_RS05585	COG1013	pyruvate-flavodoxin oxidoreductase activity
FUT83_RS05585	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FUT83_RS05585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FUT83_RS05610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FUT83_RS05625	COG1162	GTPase activity
FUT83_RS05630	COG1193	negative regulation of DNA recombination
FUT83_RS05645	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FUT83_RS05655	COG3951	Flagellar rod assembly protein muramidase FlgJ
FUT83_RS05660	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FUT83_RS05670	COG1047	Peptidyl-prolyl cis-trans
FUT83_RS05680	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FUT83_RS05690	COG1309	transcriptional regulator
FUT83_RS05700	COG0037	tRNA processing
FUT83_RS05705	COG1879	ABC-type sugar transport system periplasmic component
FUT83_RS05710	COG1692	metallophosphoesterase
FUT83_RS05730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FUT83_RS05745	COG1115	amino acid carrier protein
FUT83_RS05755	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FUT83_RS05775	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FUT83_RS05795	COG0530	calcium, potassium:sodium antiporter activity
FUT83_RS05815	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FUT83_RS05815	COG0321	lipoyl(octanoyl) transferase activity
FUT83_RS05835	COG2204	response regulator
FUT83_RS05840	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FUT83_RS05850	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FUT83_RS05865	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FUT83_RS05890	COG0405	Gamma-glutamyltransferase
FUT83_RS05905	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FUT83_RS05910	COG0587	DNA-directed DNA polymerase activity
FUT83_RS05915	COG0762	integral membrane protein
FUT83_RS05920	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FUT83_RS05925	COG0584	glycerophosphoryl diester phosphodiesterase
FUT83_RS05930	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FUT83_RS05940	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FUT83_RS05945	COG0542	response to heat
FUT83_RS05975	COG3525	Glycosyl hydrolase, family 20, catalytic domain
FUT83_RS05980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FUT83_RS06000	COG0826	peptidase U32
FUT83_RS06025	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FUT83_RS06070	COG1366	Belongs to the anti-sigma-factor antagonist family
FUT83_RS06080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FUT83_RS06090	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FUT83_RS06095	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FUT83_RS06125	COG1640	4-alpha-glucanotransferase
FUT83_RS06150	COG1136	(ABC) transporter
FUT83_RS06155	COG0672	)-iron permease
FUT83_RS06160	COG3470	protein probably involved in high-affinity Fe2 transport
FUT83_RS06175	COG1136	(ABC) transporter
FUT83_RS06175	COG0577	efflux transmembrane transporter activity
FUT83_RS06190	COG1136	(ABC) transporter
FUT83_RS06210	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FUT83_RS06210	COG3976	FMN-binding domain protein
FUT83_RS06215	COG2070	2-Nitropropane dioxygenase
FUT83_RS06220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FUT83_RS06240	COG0739	heme binding
FUT83_RS06260	COG0666	response to abiotic stimulus
FUT83_RS06295	COG2502	aspartate--ammonia ligase
FUT83_RS06300	COG1704	LemA family
FUT83_RS06310	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FUT83_RS06340	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FUT83_RS06345	COG0301	tRNA thio-modification
FUT83_RS06360	COG4786	Flagellar basal body rod
FUT83_RS06365	COG2188	Transcriptional regulator
FUT83_RS06370	COG2190	(PTS) system
FUT83_RS06370	COG1263	PTS System
FUT83_RS06370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FUT83_RS06375	COG0561	phosphatase activity
FUT83_RS06380	COG2723	6-phospho-beta-galactosidase activity
FUT83_RS06385	COG0363	glucosamine-6-phosphate deaminase activity
FUT83_RS06390	COG0714	Associated with various cellular activities
FUT83_RS06400	COG1305	Transglutaminase-like
FUT83_RS06405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FUT83_RS06420	COG0706	membrane insertase activity
FUT83_RS06425	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FUT83_RS06435	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FUT83_RS06445	COG1640	4-alpha-glucanotransferase
FUT83_RS06450	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FUT83_RS06460	COG3328	transposase activity
FUT83_RS06465	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FUT83_RS06470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT83_RS06485	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FUT83_RS06500	COG2003	Belongs to the UPF0758 family
FUT83_RS06560	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FUT83_RS06575	COG0017	Asparaginyl-tRNA synthetase
FUT83_RS06580	COG0840	transmembrane signaling receptor activity
FUT83_RS06590	COG3630	sodium ion export across plasma membrane
FUT83_RS06595	COG5016	pyruvate
FUT83_RS06595	COG0511	ligase activity, forming carbon-carbon bonds
FUT83_RS06605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FUT83_RS06610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FUT83_RS06625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FUT83_RS06630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FUT83_RS06640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FUT83_RS06645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FUT83_RS06655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FUT83_RS06725	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FUT83_RS06740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FUT83_RS06755	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FUT83_RS06775	COG0542	response to heat
FUT83_RS06785	COG0457	Tetratricopeptide repeat
FUT83_RS06790	COG1475	DNA binding
FUT83_RS06795	COG1438	arginine binding
FUT83_RS06800	COG0251	oxidation-reduction process
FUT83_RS06830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FUT83_RS06870	COG2244	polysaccharide biosynthetic process
FUT83_RS06875	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FUT83_RS06920	COG0673	inositol 2-dehydrogenase activity
FUT83_RS06930	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
FUT83_RS06930	COG0028	Belongs to the TPP enzyme family
FUT83_RS06965	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FUT83_RS06985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FUT83_RS07000	COG1178	ABC-type Fe3 transport system permease component
FUT83_RS07005	COG3842	ATPase activity
FUT83_RS07035	COG0395	ABC-type sugar transport system, permease component
FUT83_RS07040	COG4209	transmembrane transport
FUT83_RS07045	COG1040	competence protein
FUT83_RS07060	COG1388	LysM domain
FUT83_RS07060	COG0741	lytic transglycosylase activity
FUT83_RS07075	COG0739	heme binding
FUT83_RS07080	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FUT83_RS07080	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FUT83_RS07085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FUT83_RS07090	COG2195	Cleaves the N-terminal amino acid of tripeptides
FUT83_RS07115	COG2226	methyltransferase
FUT83_RS07130	COG3328	transposase activity
FUT83_RS07150	COG0629	single-stranded DNA binding
FUT83_RS07180	COG3723	Recombinational DNA repair protein, rece pathway
FUT83_RS07200	COG5377	YqaJ viral recombinase family
FUT83_RS07215	COG1132	(ABC) transporter
FUT83_RS07220	COG1132	(ABC) transporter
FUT83_RS07225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FUT83_RS07235	COG1187	pseudouridine synthase activity
FUT83_RS07280	COG1132	(ABC) transporter
FUT83_RS07285	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FUT83_RS07305	COG3706	GGDEF domain
FUT83_RS07320	COG1413	lyase activity
FUT83_RS07330	COG1012	belongs to the aldehyde dehydrogenase family
FUT83_RS07335	COG0673	inositol 2-dehydrogenase activity
FUT83_RS07340	COG1172	Belongs to the binding-protein-dependent transport system permease family
FUT83_RS07350	COG1879	ABC-type sugar transport system periplasmic component
FUT83_RS07620	COG1227	inorganic diphosphatase activity
FUT83_RS07620	COG0517	IMP dehydrogenase activity
FUT83_RS07630	COG0768	penicillin binding
FUT83_RS07635	COG2604	Protein of unknown function DUF115
FUT83_RS07660	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FUT83_RS07665	COG1760	l-serine dehydratase
FUT83_RS07670	COG1760	l-serine dehydratase
FUT83_RS07675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FUT83_RS07675	COG0574	Belongs to the PEP-utilizing enzyme family
FUT83_RS07700	COG1592	Rubrerythrin
FUT83_RS07710	COG2604	Protein of unknown function DUF115
FUT83_RS07715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FUT83_RS07720	COG0803	Belongs to the bacterial solute-binding protein 9 family
FUT83_RS07725	COG1121	(ABC) transporter
FUT83_RS07730	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FUT83_RS07735	COG1473	amidohydrolase
FUT83_RS07755	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FUT83_RS07795	COG0626	cystathionine gamma-synthase activity
FUT83_RS07800	COG3457	Alanine racemase
FUT83_RS07805	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FUT83_RS07845	COG0552	protein localization to endoplasmic reticulum
FUT83_RS07860	COG1136	(ABC) transporter
FUT83_RS07875	COG3869	Catalyzes the specific phosphorylation of arginine residues in
FUT83_RS07895	COG1086	Polysaccharide biosynthesis protein
FUT83_RS07900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FUT83_RS07905	COG1573	uracil-dna glycosylase
FUT83_RS07915	COG0488	(ABC) transporter
FUT83_RS07915	COG0488	(ABC) transporter
FUT83_RS07925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FUT83_RS07935	COG0564	pseudouridine synthase activity
FUT83_RS07960	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FUT83_RS07960	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FUT83_RS07970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FUT83_RS07975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FUT83_RS07990	COG2885	chlorophyll binding
FUT83_RS08020	COG0322	excinuclease ABC activity
FUT83_RS08025	COG0802	atpase or kinase
FUT83_RS08030	COG1214	PFAM Peptidase M22, glycoprotease
FUT83_RS08055	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FUT83_RS08070	COG3579	cysteine-type endopeptidase activity
FUT83_RS08080	COG0110	maltose O-acetyltransferase activity
FUT83_RS08135	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FUT83_RS08150	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FUT83_RS08155	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FUT83_RS08165	COG1929	Belongs to the glycerate kinase type-1 family
FUT83_RS08170	COG2610	gluconate transmembrane transporter activity
FUT83_RS08190	COG0714	Associated with various cellular activities
FUT83_RS08200	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FUT83_RS08245	COG1132	(ABC) transporter
FUT83_RS08250	COG1132	(ABC) transporter
FUT83_RS08255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FUT83_RS08260	COG1120	ATPase activity
FUT83_RS08300	COG2226	methyltransferase
FUT83_RS08335	COG3177	Filamentation induced by cAMP protein fic
FUT83_RS08370	COG2226	methyltransferase
FUT83_RS08395	COG1129	ABC transporter
FUT83_RS08415	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FUT83_RS08445	COG3052	prosthetic group binding
FUT83_RS08485	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FUT83_RS08515	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FUT83_RS08525	COG0581	inorganic phosphate transmembrane transporter activity
FUT83_RS08530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FUT83_RS08535	COG0704	Plays a role in the regulation of phosphate uptake
FUT83_RS08545	COG5002	protein histidine kinase activity
FUT83_RS08550	COG0840	transmembrane signaling receptor activity
FUT83_RS08555	COG0823	Involved in the tonB-independent uptake of proteins
FUT83_RS08555	COG1506	peptidase
FUT83_RS08555	COG4946	Tricorn protease homolog
FUT83_RS08565	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FUT83_RS08580	COG0840	transmembrane signaling receptor activity
FUT83_RS08585	COG0840	transmembrane signaling receptor activity
FUT83_RS08590	COG1516	flagellar protein fliS
FUT83_RS08600	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FUT83_RS08605	COG3118	belongs to the thioredoxin family
FUT83_RS08615	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FUT83_RS08615	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FUT83_RS08620	COG5002	protein histidine kinase activity
FUT83_RS08620	COG5001	Diguanylate cyclase
FUT83_RS08640	COG2197	response regulator
FUT83_RS08655	COG0493	'glutamate synthase
FUT83_RS08660	COG0543	2 iron, 2 sulfur cluster binding
FUT83_RS08665	COG0740	serine-type endopeptidase activity
FUT83_RS08680	COG0531	amino acid
FUT83_RS08720	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FUT83_RS08770	COG0563	adenylate kinase activity
FUT83_RS08780	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FUT83_RS08785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FUT83_RS08790	COG0571	ribonuclease III activity
FUT83_RS08820	COG3735	TraB family
FUT83_RS08825	COG0180	Tryptophanyl-tRNA synthetase
FUT83_RS08835	COG1131	(ABC) transporter
FUT83_RS08845	COG0574	Belongs to the PEP-utilizing enzyme family
FUT83_RS08845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FUT83_RS08860	COG2304	oxidoreductase activity
FUT83_RS08865	COG0426	domain, Protein
FUT83_RS08865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FUT83_RS08875	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FUT83_RS08890	COG1394	ATPase activity, coupled to movement of substances
FUT83_RS08900	COG0085	RNA polymerase activity
FUT83_RS08915	COG0081	regulation of translation
FUT83_RS08920	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FUT83_RS08925	COG0250	Participates in transcription elongation, termination and antitermination
FUT83_RS08930	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FUT83_RS08940	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FUT83_RS08950	COG0716	FMN binding
FUT83_RS08970	COG1869	D-ribose catabolic process
FUT83_RS08975	COG1129	ABC transporter
FUT83_RS08980	COG1172	Belongs to the binding-protein-dependent transport system permease family
FUT83_RS08985	COG1879	ABC-type sugar transport system periplasmic component
FUT83_RS09020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FUT83_RS09035	COG0300	oxidoreductase activity
FUT83_RS09045	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FUT83_RS09050	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FUT83_RS09055	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FUT83_RS09075	COG0326	Molecular chaperone. Has ATPase activity
FUT83_RS09080	COG0517	IMP dehydrogenase activity
FUT83_RS09110	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FUT83_RS09125	COG0840	transmembrane signaling receptor activity
FUT83_RS09135	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FUT83_RS09155	COG2604	Protein of unknown function DUF115
FUT83_RS09185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FUT83_RS09190	COG1418	mRNA catabolic process
FUT83_RS09205	COG1686	Belongs to the peptidase S11 family
FUT83_RS09215	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FUT83_RS09445	COG0514	ATP-dependent DNA helicase (RecQ)
FUT83_RS09450	COG0395	ABC-type sugar transport system, permease component
FUT83_RS09455	COG1175	transmembrane transport
FUT83_RS09485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FUT83_RS09490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT83_RS09490	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT83_RS09500	COG3037	sugar-specific permease SgaT UlaA
FUT83_RS09515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FUT83_RS09525	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FUT83_RS09530	COG2911	Protein conserved in bacteria
FUT83_RS09535	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FUT83_RS09545	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FUT83_RS09550	COG0534	Mate efflux family protein
FUT83_RS09570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FUT83_RS09580	COG4608	Belongs to the ABC transporter superfamily
FUT83_RS09585	COG0444	Belongs to the ABC transporter superfamily
FUT83_RS09590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FUT83_RS09595	COG0601	transmembrane transport
FUT83_RS09605	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FUT83_RS09610	COG0671	phosphoesterase, PA-phosphatase related
FUT83_RS09625	COG0497	DNA recombination
FUT83_RS09630	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FUT83_RS09635	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FUT83_RS09640	COG0835	chemotaxis
FUT83_RS09655	COG0840	transmembrane signaling receptor activity
FUT83_RS09690	COG3876	Protein conserved in bacteria
FUT83_RS09695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FUT83_RS09700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FUT83_RS09705	COG0569	domain protein
FUT83_RS09720	COG0714	Associated with various cellular activities
FUT83_RS09735	COG1366	Belongs to the anti-sigma-factor antagonist family
FUT83_RS09755	COG0653	protein targeting
FUT83_RS09760	COG1132	(ABC) transporter
FUT83_RS09765	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FUT83_RS09770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FUT83_RS09775	COG0626	cystathionine gamma-synthase activity
FUT83_RS09785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FUT83_RS09785	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FUT83_RS09785	COG1013	pyruvate-flavodoxin oxidoreductase activity
FUT83_RS09785	COG0674	pyruvate-flavodoxin oxidoreductase activity
FUT83_RS09805	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FUT83_RS09810	COG4209	transmembrane transport
FUT83_RS09815	COG0395	ABC-type sugar transport system, permease component
FUT83_RS09825	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
FUT83_RS09830	COG1609	Transcriptional regulator
FUT83_RS09835	COG0142	geranyltranstransferase activity
FUT83_RS09845	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FUT83_RS09855	COG3681	Belongs to the UPF0597 family
FUT83_RS09865	COG0561	phosphatase activity
FUT83_RS09875	COG0733	neurotransmitter:sodium symporter activity
FUT83_RS09880	COG0210	DNA helicase
FUT83_RS09925	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FUT83_RS09935	COG0335	large ribosomal subunit rRNA binding
FUT83_RS09940	COG0336	Belongs to the RNA methyltransferase TrmD family
FUT83_RS09945	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FUT83_RS09950	COG1837	Belongs to the UPF0109 family
FUT83_RS09955	COG0228	four-way junction DNA binding
FUT83_RS09990	COG1254	Belongs to the acylphosphatase family
FUT83_RS10010	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FUT83_RS10015	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FUT83_RS10020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FUT83_RS10025	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FUT83_RS10050	COG0739	heme binding
FUT83_RS10065	COG0739	heme binding
FUT83_RS10075	COG0351	phosphomethylpyrimidine kinase
FUT83_RS10080	COG0495	leucyl-tRNA aminoacylation
FUT83_RS10090	COG2089	acid synthase
FUT83_RS10105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FUT83_RS10110	COG2373	Large extracellular alpha-helical protein
FUT83_RS10115	COG4953	penicillin-binding protein 1C
FUT83_RS10120	COG1192	Involved in chromosome partitioning
FUT83_RS10125	COG1475	DNA binding
FUT83_RS10135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FUT83_RS10380	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FUT83_RS10450	COG2932	Transcriptional regulator
FUT83_RS10465	COG0513	Belongs to the DEAD box helicase family
FUT83_RS10470	COG0577	efflux transmembrane transporter activity
FUT83_RS10475	COG0577	efflux transmembrane transporter activity
FUT83_RS10480	COG1136	(ABC) transporter
FUT83_RS10495	COG0052	Belongs to the universal ribosomal protein uS2 family
FUT83_RS10500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FUT83_RS10505	COG0233	cytoplasmic translational termination
FUT83_RS10510	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FUT83_RS10515	COG4589	Belongs to the CDS family
FUT83_RS10520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FUT83_RS10525	COG0750	zinc metalloprotease
FUT83_RS10550	COG0681	Belongs to the peptidase S26 family
FUT83_RS10555	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FUT83_RS10560	COG0616	signal peptide processing
FUT83_RS10590	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FUT83_RS10605	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FUT83_RS10605	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FUT83_RS10610	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FUT83_RS10615	COG0617	tRNA 3'-terminal CCA addition
FUT83_RS10700	COG3328	transposase activity
FUT83_RS10715	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FUT83_RS10745	COG1744	ABC transporter substrate-binding protein PnrA-like
FUT83_RS10750	COG3845	ABC transporter
FUT83_RS10755	COG4603	Belongs to the binding-protein-dependent transport system permease family
FUT83_RS10760	COG1079	Belongs to the binding-protein-dependent transport system permease family
FUT83_RS10790	COG1373	ATPase (AAA superfamily
FUT83_RS10830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FUT83_RS10885	COG0488	(ABC) transporter
FUT83_RS10915	COG0494	nUDIX hydrolase
FUT83_RS10925	COG0205	6-phosphofructokinase activity
FUT83_RS10930	COG0629	single-stranded DNA binding
FUT83_RS10945	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FUT83_RS10970	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FUT83_RS10970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FUT83_RS10975	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FUT83_RS10990	COG0395	ABC-type sugar transport system, permease component
FUT83_RS11005	COG1175	transmembrane transport
FUT83_RS11010	COG0395	ABC-type sugar transport system, permease component
FUT83_RS11040	COG0254	rRNA binding
FUT83_RS11045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FUT83_RS11050	COG1546	Belongs to the CinA family
FUT83_RS11050	COG1058	Belongs to the CinA family
FUT83_RS11060	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FUT83_RS11070	COG0776	regulation of translation
FUT83_RS11075	COG0268	Binds directly to 16S ribosomal RNA
FUT83_RS11080	COG2357	RelA SpoT domain protein
FUT83_RS11095	COG0860	N-Acetylmuramoyl-L-alanine amidase
FUT83_RS11115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FUT83_RS11120	COG3118	belongs to the thioredoxin family
FUT83_RS11125	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FUT83_RS11130	COG0084	hydrolase, TatD family'
FUT83_RS11140	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FUT83_RS11190	COG0826	peptidase U32
FUT83_RS11200	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FUT83_RS11205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FUT83_RS11230	COG0126	phosphoglycerate kinase activity
FUT83_RS11235	COG0149	triose-phosphate isomerase activity
FUT83_RS11245	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FUT83_RS11250	COG0588	phosphoglycerate mutase activity
FUT83_RS11275	COG0789	Transcriptional regulator
FUT83_RS11295	COG1979	alcohol dehydrogenase
FUT83_RS11305	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FUT83_RS11310	COG0786	glutamate:sodium symporter activity
FUT83_RS11330	COG2197	response regulator
FUT83_RS11335	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FUT83_RS11355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FUT83_RS11365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FUT83_RS11395	COG0167	dihydroorotate dehydrogenase activity
FUT83_RS11410	COG1199	ATP-dependent helicase activity
FUT83_RS11415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FUT83_RS11420	COG0006	proline dipeptidase activity
FUT83_RS11430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FUT83_RS11470	COG0484	heat shock protein binding
FUT83_RS11475	COG0024	Methionine aminopeptidase
FUT83_RS11480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FUT83_RS11495	COG3064	Membrane
FUT83_RS11500	COG2211	Major facilitator Superfamily
FUT83_RS11510	COG1598	PFAM Uncharacterised protein family UPF0150
FUT83_RS11525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FUT83_RS11530	COG1245	4Fe-4S binding domain
FUT83_RS11530	COG2878	Part of a membrane complex involved in electron transport
FUT83_RS11535	COG4657	Part of a membrane complex involved in electron transport
FUT83_RS11540	COG4660	Part of a membrane complex involved in electron transport
FUT83_RS11550	COG4658	electron transport chain
FUT83_RS11555	COG4656	Part of a membrane complex involved in electron transport
FUT83_RS11575	COG1234	tRNA 3'-trailer cleavage
FUT83_RS11585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FUT83_RS11590	COG0358	DNA primase activity
FUT83_RS11595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FUT83_RS11615	COG1077	Cell shape determining protein MreB Mrl
FUT83_RS11630	COG0768	penicillin binding
FUT83_RS11635	COG0772	Belongs to the SEDS family
FUT83_RS11640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FUT83_RS11650	COG1104	cysteine desulfurase activity
FUT83_RS11665	COG0709	Synthesizes selenophosphate from selenide and ATP
FUT83_RS11675	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FUT83_RS11675	COG3608	succinylglutamate desuccinylase aspartoacylase
FUT83_RS11680	COG0746	molybdenum cofactor guanylyltransferase activity
FUT83_RS11685	COG3842	ATPase activity
FUT83_RS11690	COG4149	molybdate abc transporter
FUT83_RS11695	COG0725	ABC transporter, periplasmic molybdate-binding protein
FUT83_RS11705	COG0521	Mo-molybdopterin cofactor biosynthetic process
FUT83_RS11720	COG0315	cyclic pyranopterin monophosphate synthase activity
FUT83_RS11725	COG1546	Belongs to the CinA family
FUT83_RS11725	COG1058	Belongs to the CinA family
FUT83_RS11730	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FUT83_RS11730	COG3608	succinylglutamate desuccinylase aspartoacylase
FUT83_RS11735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FUT83_RS11745	COG0402	S-adenosylhomocysteine deaminase activity
FUT83_RS11750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FUT83_RS11750	COG0493	'glutamate synthase
FUT83_RS11760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FUT83_RS11765	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FUT83_RS11785	COG3404	Formiminotransferase-cyclodeaminase
FUT83_RS11800	COG2986	histidine ammonia-lyase
FUT83_RS11805	COG2056	Na+-H+ antiporter family
FUT83_RS11815	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FUT83_RS11820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FUT83_RS11825	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FUT83_RS11845	COG0101	tRNA pseudouridine synthase activity
FUT83_RS11850	COG0297	glycogen (starch) synthase activity
FUT83_RS11860	COG0427	acetyl-CoA hydrolase
FUT83_RS11865	COG1024	Enoyl-CoA hydratase
FUT83_RS11870	COG1250	3-hydroxyacyl-CoA dehydrogenase
FUT83_RS11875	COG0426	domain, Protein
FUT83_RS11880	COG1960	acyl-CoA dehydrogenase activity
FUT83_RS11885	COG0183	Belongs to the thiolase family
FUT83_RS11905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FUT83_RS11910	COG2890	protein-(glutamine-N5) methyltransferase activity
FUT83_RS11915	COG1022	Amp-dependent synthetase and ligase
FUT83_RS11920	COG1321	iron dependent repressor
FUT83_RS11925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FUT83_RS11930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FUT83_RS11935	COG1121	(ABC) transporter
FUT83_RS11940	COG0803	Belongs to the bacterial solute-binding protein 9 family
FUT83_RS11955	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FUT83_RS12025	COG0297	glycogen (starch) synthase activity
FUT83_RS12075	COG2738	Putative neutral zinc metallopeptidase
FUT83_RS12105	COG2255	four-way junction helicase activity
FUT83_RS12110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FUT83_RS12125	COG1362	aminopeptidase activity
FUT83_RS12135	COG1570	exodeoxyribonuclease VII activity
FUT83_RS12160	COG4750	Nucleotidyl transferase
FUT83_RS12165	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FUT83_RS12195	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FUT83_RS12200	COG1214	PFAM Peptidase M22, glycoprotease
FUT83_RS12200	COG0456	acetyltransferase
FUT83_RS12205	COG1811	Na channel or pump
FUT83_RS12220	COG2059	Chromate
FUT83_RS12245	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FUT83_RS12250	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FUT83_RS12260	COG1196	nuclear chromosome segregation
FUT83_RS12270	COG2201	protein-glutamate methylesterase activity
FUT83_RS12280	COG0835	chemotaxis
FUT83_RS12285	COG0643	Histidine kinase
FUT83_RS12285	COG2198	Histidine kinase
FUT83_RS12310	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FUT83_RS12315	COG1882	Formate acetyltransferase
FUT83_RS12335	COG1253	flavin adenine dinucleotide binding
FUT83_RS12380	COG1757	Na H antiporter
FUT83_RS12385	COG0357	Ribosomal RNA small subunit methyltransferase G
FUT83_RS12430	COG0840	transmembrane signaling receptor activity
FUT83_RS12455	COG0012	GTP binding
FUT83_RS12460	COG1268	BioY protein
FUT83_RS12465	COG1122	ATPase activity
FUT83_RS12485	COG3959	Transketolase, thiamine diphosphate binding domain
FUT83_RS12490	COG3958	Transketolase
FUT83_RS12495	COG0584	glycerophosphoryl diester phosphodiesterase
FUT83_RS12520	COG2801	Transposase and inactivated derivatives
FUT83_RS12535	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FUT83_RS12570	COG1181	Belongs to the D-alanine--D-alanine ligase family
FUT83_RS12580	COG1132	(ABC) transporter
FUT83_RS12585	COG1132	(ABC) transporter
FUT83_RS12590	COG1132	(ABC) transporter
FUT83_RS12595	COG1132	(ABC) transporter
FUT83_RS12600	COG4608	Belongs to the ABC transporter superfamily
FUT83_RS12605	COG0444	Belongs to the ABC transporter superfamily
FUT83_RS12610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FUT83_RS12630	COG0492	ferredoxin-NADP+ reductase activity
FUT83_RS12635	COG1472	Belongs to the glycosyl hydrolase 3 family
FUT83_RS12655	COG0450	alkyl hydroperoxide reductase
FUT83_RS12660	COG1349	DNA-binding transcription factor activity
FUT83_RS12665	COG1105	Belongs to the carbohydrate kinase PfkB family
FUT83_RS12670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT83_RS12670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FUT83_RS12670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FUT83_RS12675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT83_RS12695	COG0640	Transcriptional regulator
FUT83_RS12705	COG2217	Heavy metal translocating P-type atpase
FUT83_RS12715	COG3177	Filamentation induced by cAMP protein fic
FUT83_RS12725	COG3385	transposase activity
FUT83_RS12780	COG0840	transmembrane signaling receptor activity
FUT83_RS12820	COG2361	Protein of unknown function DUF86
FUT83_RS12855	COG2361	Protein of unknown function DUF86
FUT83_RS12870	COG0840	transmembrane signaling receptor activity
FUT83_RS12915	COG3209	COG3209 Rhs family protein
FUT83_RS12955	COG2189	Belongs to the N(4) N(6)-methyltransferase family
FUT83_RS12975	COG0840	transmembrane signaling receptor activity
FUT83_RS13035	COG3385	transposase activity
FUT83_RS13070	COG0210	DNA helicase
FUT83_RS13085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FUT83_RS13095	COG1522	sequence-specific DNA binding
FUT83_RS13100	COG0436	Aminotransferase
FUT83_RS13105	COG1114	Component of the transport system for branched-chain amino acids
FUT83_RS13110	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FUT83_RS13115	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FUT83_RS13120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FUT83_RS13135	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FUT83_RS13140	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FUT83_RS13145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FUT83_RS13170	COG0655	NAD(P)H dehydrogenase (quinone) activity
FUT83_RS13415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FUT83_RS13430	COG1252	NADH dehydrogenase
FUT83_RS13440	COG1960	acyl-CoA dehydrogenase activity
FUT83_RS13445	COG2086	electron transfer activity
FUT83_RS13450	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FUT83_RS13480	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FUT83_RS13485	COG1480	7TM receptor with intracellular HD hydrolase
FUT83_RS13490	COG1702	phosphate starvation-inducible protein PhoH
FUT83_RS13500	COG0018	arginyl-trna synthetase
FUT83_RS13510	COG2235	arginine
FUT83_RS13515	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FUT83_RS13520	COG0549	Belongs to the carbamate kinase family
FUT83_RS13530	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FUT83_RS13535	COG0534	Mate efflux family protein
FUT83_RS13540	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FUT83_RS13565	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FUT83_RS13570	COG1966	Carbon starvation protein
FUT83_RS13795	COG1722	exodeoxyribonuclease VII activity
FUT83_RS13800	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FUT83_RS13805	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FUT83_RS13810	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FUT83_RS13830	COG0395	ABC-type sugar transport system, permease component
FUT83_RS13840	COG1653	transport
FUT83_RS13850	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FUT83_RS13860	COG2084	Dehydrogenase
FUT83_RS13875	COG0330	HflC and HflK could
FUT83_RS13895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FUT83_RS13910	COG2197	response regulator
FUT83_RS13915	COG4585	Histidine kinase
FUT83_RS13925	COG0166	Belongs to the GPI family
FUT83_RS13980	COG0482	sulfurtransferase activity
FUT83_RS13990	COG1674	ftsk spoiiie
FUT83_RS13995	COG1968	undecaprenyl-diphosphatase activity
FUT83_RS14035	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FUT83_RS14040	COG1752	Esterase of the alpha-beta hydrolase superfamily
FUT83_RS14045	COG5341	Protein conserved in bacteria
FUT83_RS14065	COG0823	Involved in the tonB-independent uptake of proteins
FUT83_RS14085	COG0564	pseudouridine synthase activity
FUT83_RS14085	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FUT83_RS14140	COG0519	Catalyzes the synthesis of GMP from XMP
FUT83_RS14150	COG0519	Catalyzes the synthesis of GMP from XMP
FUT83_RS14190	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FUT83_RS14190	COG0515	serine threonine protein kinase
FUT83_RS14195	COG0811	peptide transport
FUT83_RS14200	COG0848	biopolymer transport protein
FUT83_RS14225	COG0203	ribosomal protein L17
FUT83_RS14230	COG0202	RNA polymerase activity
FUT83_RS14235	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FUT83_RS14245	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FUT83_RS14255	COG0200	Binds to the 23S rRNA
FUT83_RS14260	COG1841	ribosomal large subunit assembly
FUT83_RS14270	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FUT83_RS14275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FUT83_RS14280	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FUT83_RS14290	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FUT83_RS14305	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FUT83_RS14310	COG0255	Belongs to the universal ribosomal protein uL29 family
FUT83_RS14320	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FUT83_RS14325	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FUT83_RS14335	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FUT83_RS14340	COG0089	rRNA binding
FUT83_RS14345	COG0088	Forms part of the polypeptide exit tunnel
FUT83_RS14350	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FUT83_RS14355	COG0051	transcription antitermination factor activity, RNA binding
FUT83_RS14360	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FUT83_RS14370	COG2823	Periplasmic or secreted lipoprotein
FUT83_RS14370	COG1652	LysM domain
FUT83_RS14375	COG2033	superoxide reductase activity
FUT83_RS14380	COG1078	dGTPase activity
FUT83_RS14410	COG1774	PSP1 C-terminal conserved region
FUT83_RS14425	COG0739	heme binding
FUT83_RS14435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FUT83_RS14445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FUT83_RS14460	COG1419	protein localization to endoplasmic reticulum
FUT83_RS14465	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FUT83_RS14470	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FUT83_RS14475	COG1684	flagellar biosynthetic protein fliR
FUT83_RS14480	COG1987	bacterial-type flagellum assembly
FUT83_RS14485	COG1338	Plays a role in the flagellum-specific transport system
FUT83_RS14495	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FUT83_RS14495	COG1776	CheC inhibitor of MCP methylation
FUT83_RS14500	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FUT83_RS14505	COG1580	Controls the rotational direction of flagella during chemotaxis
FUT83_RS14510	COG1360	Flagellar Motor Protein
FUT83_RS14530	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FUT83_RS14555	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FUT83_RS14565	COG0840	transmembrane signaling receptor activity
FUT83_RS14580	COG1164	Oligoendopeptidase f
FUT83_RS14585	COG1690	Belongs to the RtcB family
FUT83_RS14590	COG2213	PTS system mannitol-specific
FUT83_RS14590	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FUT83_RS14595	COG1349	DNA-binding transcription factor activity
FUT83_RS14600	COG1063	alcohol dehydrogenase
FUT83_RS14610	COG0235	Class ii aldolase
FUT83_RS14615	COG0058	SHG alpha-glucan phosphorylase activity
FUT83_RS14620	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FUT83_RS14630	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FUT83_RS14630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FUT83_RS14630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FUT83_RS14655	COG1151	hydroxylamine reductase activity
FUT83_RS14685	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FUT83_RS14720	COG0656	L-ascorbic acid biosynthetic process
FUT83_RS14750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FUT83_RS14765	COG3842	ATPase activity
FUT83_RS14770	COG1178	ABC-type Fe3 transport system permease component
FUT83_RS14775	COG3842	ATPase activity
FUT83_RS14790	COG0840	transmembrane signaling receptor activity
FUT83_RS14795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FUT83_RS14800	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FUT83_RS14810	COG0217	transcriptional regulatory protein
FUT83_RS14820	COG0697	spore germination
FUT83_RS14825	COG2982	Protein involved in outer membrane biogenesis
FUT83_RS14830	COG3216	Uncharacterized protein conserved in bacteria (DUF2062)
FUT83_RS14840	COG1486	melibiose metabolic process
FUT83_RS14845	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FUT83_RS14850	COG1022	Amp-dependent synthetase and ligase
FUT83_RS14855	COG3885	ferrous iron binding
FUT83_RS14855	COG2078	PFAM AMMECR1 domain protein
FUT83_RS14890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FUT83_RS14895	COG1234	tRNA 3'-trailer cleavage
FUT83_RS14915	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FUT83_RS14935	COG1129	ABC transporter
FUT83_RS14960	COG0557	exoribonuclease II activity
FUT83_RS14980	COG2376	Dihydroxyacetone kinase
FUT83_RS14990	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FUT83_RS15005	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FUT83_RS15010	COG1469	GTP cyclohydrolase I activity
FUT83_RS15025	COG0863	Belongs to the N(4) N(6)-methyltransferase family
FUT83_RS15035	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FUT83_RS15050	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FUT83_RS15055	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FUT83_RS15075	COG3956	TIGRFAM MazG family protein
FUT83_RS15105	COG1847	R3H domain protein
FUT83_RS15110	COG1191	sigma factor activity
FUT83_RS15125	COG0673	inositol 2-dehydrogenase activity
FUT83_RS15140	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FUT83_RS15155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FUT83_RS15160	COG0793	Belongs to the peptidase S41A family
FUT83_RS15165	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FUT83_RS15170	COG0488	(ABC) transporter
FUT83_RS15485	COG2030	dehydratase
FUT83_RS15495	COG2610	gluconate transmembrane transporter activity
FUT83_RS15515	COG1129	ABC transporter
FUT83_RS15520	COG1172	Belongs to the binding-protein-dependent transport system permease family
FUT83_RS15525	COG1172	Belongs to the binding-protein-dependent transport system permease family
FUT83_RS15565	COG0719	Fe-S assembly protein
FUT83_RS15570	COG0719	Fe-S assembly protein
FUT83_RS15575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FUT83_RS15580	COG0822	iron-sulfur transferase activity
FUT83_RS15600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FUT83_RS15605	COG0670	Belongs to the BI1 family
FUT83_RS15615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FUT83_RS15625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FUT83_RS15635	COG1129	ABC transporter
FUT83_RS15640	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FUT83_RS15650	COG0446	pyridine nucleotide-disulphide oxidoreductase
FUT83_RS15675	COG0116	Belongs to the methyltransferase superfamily
FUT83_RS15680	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FUT83_RS15685	COG1687	branched-chain amino acid