locus-tag	class	description
TREPR_RS00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TREPR_RS00015	COG0592	DNA-directed DNA polymerase activity
TREPR_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TREPR_RS00040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TREPR_RS00045	COG1129	ABC transporter
TREPR_RS00050	COG1172	Belongs to the binding-protein-dependent transport system permease family
TREPR_RS00055	COG1879	ABC-type sugar transport system periplasmic component
TREPR_RS00065	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TREPR_RS00075	COG0113	porphobilinogen synthase activity
TREPR_RS00090	COG1648	precorrin-2 dehydrogenase activity
TREPR_RS00090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TREPR_RS00105	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TREPR_RS00110	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
TREPR_RS00115	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
TREPR_RS00120	COG4208	sulfate ABC transporter
TREPR_RS00135	COG0175	sulfate reduction
TREPR_RS00140	COG2895	sulfate adenylyltransferase (ATP) activity
TREPR_RS00145	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
TREPR_RS00160	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TREPR_RS00185	COG1640	4-alpha-glucanotransferase
TREPR_RS00215	COG3845	ABC transporter
TREPR_RS00220	COG1744	ABC transporter substrate-binding protein PnrA-like
TREPR_RS00230	COG0785	Cytochrome C biogenesis protein
TREPR_RS00245	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TREPR_RS00250	COG0517	IMP dehydrogenase activity
TREPR_RS00250	COG0516	GMP reductase activity
TREPR_RS00285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TREPR_RS00290	COG0519	Catalyzes the synthesis of GMP from XMP
TREPR_RS00290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TREPR_RS00320	COG1487	ribonuclease activity
TREPR_RS00345	COG1215	transferase activity, transferring glycosyl groups
TREPR_RS00375	COG0438	transferase activity, transferring glycosyl groups
TREPR_RS00430	COG2203	Gaf domain
TREPR_RS00430	COG2199	diguanylate cyclase activity
TREPR_RS00435	COG0784	Response regulator, receiver
TREPR_RS00435	COG2205	protein histidine kinase activity
TREPR_RS00460	COG0714	Associated with various cellular activities
TREPR_RS00470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TREPR_RS00475	COG1022	Amp-dependent synthetase and ligase
TREPR_RS00485	COG2195	Cleaves the N-terminal amino acid of tripeptides
TREPR_RS00495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TREPR_RS00520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TREPR_RS00540	COG4191	Histidine kinase
TREPR_RS00560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TREPR_RS00570	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TREPR_RS00590	COG2900	Belongs to the SlyX family
TREPR_RS00595	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TREPR_RS00600	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TREPR_RS00620	COG3191	aminopeptidase activity
TREPR_RS00625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TREPR_RS00655	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TREPR_RS00665	COG1063	alcohol dehydrogenase
TREPR_RS00670	COG1028	Short-chain dehydrogenase reductase Sdr
TREPR_RS00675	COG1349	DNA-binding transcription factor activity
TREPR_RS00680	COG1349	DNA-binding transcription factor activity
TREPR_RS00700	COG0629	single-stranded DNA binding
TREPR_RS00710	COG0826	peptidase U32
TREPR_RS00725	COG1410	methionine synthase
TREPR_RS00725	COG0646	methionine synthase
TREPR_RS00730	COG0534	Mate efflux family protein
TREPR_RS00780	COG1196	nuclear chromosome segregation
TREPR_RS00785	COG3842	ATPase activity
TREPR_RS00795	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TREPR_RS00860	COG0584	glycerophosphoryl diester phosphodiesterase
TREPR_RS00865	COG1176	ABC-type spermidine putrescine transport system, permease component I
TREPR_RS00875	COG3842	ATPase activity
TREPR_RS00900	COG2205	protein histidine kinase activity
TREPR_RS00900	COG0784	Response regulator, receiver
TREPR_RS00925	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TREPR_RS00945	COG1842	Phage shock protein A
TREPR_RS00975	COG0793	Belongs to the peptidase S41A family
TREPR_RS01015	COG0840	transmembrane signaling receptor activity
TREPR_RS01030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TREPR_RS01075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TREPR_RS01105	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TREPR_RS01190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TREPR_RS01195	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TREPR_RS01215	COG1696	Membrane protein involved in D-alanine export
TREPR_RS01225	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
TREPR_RS01225	COG2755	lipolytic protein G-D-S-L family
TREPR_RS01240	COG2801	Transposase and inactivated derivatives
TREPR_RS01260	COG0697	spore germination
TREPR_RS01265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TREPR_RS01285	COG0417	DNA replication proofreading
TREPR_RS01290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TREPR_RS01300	COG1472	Belongs to the glycosyl hydrolase 3 family
TREPR_RS01370	COG0492	ferredoxin-NADP+ reductase activity
TREPR_RS01405	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TREPR_RS01425	COG1175	transmembrane transport
TREPR_RS01440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TREPR_RS01445	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TREPR_RS01450	COG0509	glycine decarboxylation via glycine cleavage system
TREPR_RS01460	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TREPR_RS01465	COG0095	Lipoate-protein ligase
TREPR_RS01470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TREPR_RS01485	COG1473	amidohydrolase
TREPR_RS01495	COG0455	bacterial-type flagellum organization
TREPR_RS01525	COG0587	DNA-directed DNA polymerase activity
TREPR_RS01535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TREPR_RS01540	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TREPR_RS01545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TREPR_RS01555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TREPR_RS01565	COG0613	PHP domain protein
TREPR_RS01575	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TREPR_RS01585	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
TREPR_RS01595	COG1272	protein, Hemolysin III
TREPR_RS01600	COG0488	(ABC) transporter
TREPR_RS01610	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TREPR_RS01615	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
TREPR_RS01640	COG2887	Belongs to the helicase family. UvrD subfamily
TREPR_RS01645	COG1074	ATP-dependent DNA helicase activity
TREPR_RS01650	COG2183	response to ionizing radiation
TREPR_RS01665	COG1309	transcriptional regulator
TREPR_RS01680	COG0534	Mate efflux family protein
TREPR_RS01685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TREPR_RS01690	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TREPR_RS01695	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TREPR_RS01705	COG1070	Carbohydrate kinase
TREPR_RS01715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TREPR_RS01720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TREPR_RS01735	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TREPR_RS01745	COG0151	Belongs to the GarS family
TREPR_RS01760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TREPR_RS01815	COG1328	CTP reductase activity
TREPR_RS01820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
TREPR_RS01825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TREPR_RS01830	COG2313	pseudouridylate synthase activity
TREPR_RS01855	COG1216	Glycosyl transferase, family 2
TREPR_RS01875	COG1132	(ABC) transporter
TREPR_RS01890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TREPR_RS01915	COG0110	maltose O-acetyltransferase activity
TREPR_RS01920	COG0438	transferase activity, transferring glycosyl groups
TREPR_RS01965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TREPR_RS01970	COG0765	amino acid transport
TREPR_RS01980	COG1045	serine acetyltransferase
TREPR_RS01985	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TREPR_RS01990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TREPR_RS02000	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
TREPR_RS02010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TREPR_RS02055	COG0084	hydrolase, TatD family'
TREPR_RS02080	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TREPR_RS02140	COG1335	isochorismatase
TREPR_RS02150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TREPR_RS02155	COG1027	Aspartate ammonia-lyase
TREPR_RS02160	COG2239	Acts as a magnesium transporter
TREPR_RS02175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TREPR_RS02190	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS02195	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS02200	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREPR_RS02205	COG0601	transmembrane transport
TREPR_RS02230	COG2885	chlorophyll binding
TREPR_RS02235	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TREPR_RS02290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TREPR_RS02295	COG0534	Mate efflux family protein
TREPR_RS02300	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TREPR_RS02305	COG0017	Asparaginyl-tRNA synthetase
TREPR_RS02310	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TREPR_RS02315	COG0154	amidase activity
TREPR_RS02350	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
TREPR_RS02370	COG2176	DNA-directed DNA polymerase activity
TREPR_RS02395	COG1120	ATPase activity
TREPR_RS02400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TREPR_RS02410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TREPR_RS02420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TREPR_RS02445	COG1592	Rubrerythrin
TREPR_RS02445	COG1773	rubredoxin
TREPR_RS02460	COG1797	cobyrinic acid a,c-diamide synthase activity
TREPR_RS02465	COG1063	alcohol dehydrogenase
TREPR_RS02470	COG1752	Esterase of the alpha-beta hydrolase superfamily
TREPR_RS02475	COG1045	serine acetyltransferase
TREPR_RS02510	COG1047	Peptidyl-prolyl cis-trans
TREPR_RS02525	COG2197	response regulator
TREPR_RS02560	COG1129	ABC transporter
TREPR_RS02565	COG1609	Transcriptional regulator
TREPR_RS02570	COG1609	Transcriptional regulator
TREPR_RS02585	COG1373	ATPase (AAA superfamily
TREPR_RS02595	COG0534	Mate efflux family protein
TREPR_RS02610	COG4085	toxin activity
TREPR_RS02610	COG1525	nuclease
TREPR_RS02610	COG0737	Belongs to the 5'-nucleotidase family
TREPR_RS02620	COG0583	DNA-binding transcription factor activity
TREPR_RS02625	COG1522	sequence-specific DNA binding
TREPR_RS02630	COG0686	Belongs to the AlaDH PNT family
TREPR_RS02635	COG1115	amino acid carrier protein
TREPR_RS02645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TREPR_RS02685	COG0724	RNA recognition motif
TREPR_RS02695	COG0205	6-phosphofructokinase activity
TREPR_RS02735	COG0601	transmembrane transport
TREPR_RS02740	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
TREPR_RS02775	COG1079	Belongs to the binding-protein-dependent transport system permease family
TREPR_RS02780	COG4603	Belongs to the binding-protein-dependent transport system permease family
TREPR_RS02785	COG3845	ABC transporter
TREPR_RS02790	COG1744	ABC transporter substrate-binding protein PnrA-like
TREPR_RS02795	COG0737	Belongs to the 5'-nucleotidase family
TREPR_RS02805	COG0084	hydrolase, TatD family'
TREPR_RS02870	COG0004	ammonium transporteR
TREPR_RS02890	COG3118	belongs to the thioredoxin family
TREPR_RS02895	COG2011	ABC-type metal ion transport system permease component
TREPR_RS02905	COG3437	response regulator, receiver
TREPR_RS02910	COG2205	protein histidine kinase activity
TREPR_RS02910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TREPR_RS02925	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TREPR_RS02930	COG0543	2 iron, 2 sulfur cluster binding
TREPR_RS02935	COG0167	dihydroorotate dehydrogenase activity
TREPR_RS02960	COG1335	isochorismatase
TREPR_RS02965	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TREPR_RS02970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TREPR_RS02995	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TREPR_RS03025	COG4786	Flagellar basal body rod
TREPR_RS03060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TREPR_RS03065	COG0728	peptidoglycan biosynthetic process
TREPR_RS03075	COG0069	glutamate synthase activity
TREPR_RS03075	COG0067	glutamate synthase
TREPR_RS03075	COG0070	glutamate synthase
TREPR_RS03080	COG1151	hydroxylamine reductase activity
TREPR_RS03100	COG0667	Aldo Keto reductase
TREPR_RS03110	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TREPR_RS03140	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TREPR_RS03145	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TREPR_RS03150	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TREPR_RS03160	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TREPR_RS03165	COG1215	transferase activity, transferring glycosyl groups
TREPR_RS03175	COG0534	Mate efflux family protein
TREPR_RS03180	COG0018	arginyl-trna synthetase
TREPR_RS03185	COG1496	oxidoreductase activity
TREPR_RS03215	COG0791	NLP P60 protein
TREPR_RS03225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TREPR_RS03235	COG3706	GGDEF domain
TREPR_RS03240	COG4702	Belongs to the UPF0303 family
TREPR_RS03285	COG0674	pyruvate-flavodoxin oxidoreductase activity
TREPR_RS03285	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TREPR_RS03305	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
TREPR_RS03310	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TREPR_RS03355	COG2197	response regulator
TREPR_RS03360	COG2197	response regulator
TREPR_RS03365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TREPR_RS03365	COG2207	Transcriptional regulator
TREPR_RS03370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TREPR_RS03370	COG2207	Transcriptional regulator
TREPR_RS03375	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TREPR_RS03385	COG0481	GTPase activity
TREPR_RS03445	COG1215	transferase activity, transferring glycosyl groups
TREPR_RS03460	COG2059	Chromate
TREPR_RS03470	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TREPR_RS03480	COG2885	chlorophyll binding
TREPR_RS03495	COG0673	inositol 2-dehydrogenase activity
TREPR_RS03530	COG2003	Belongs to the UPF0758 family
TREPR_RS03535	COG0667	Aldo Keto reductase
TREPR_RS03550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TREPR_RS03555	COG2201	protein-glutamate methylesterase activity
TREPR_RS03560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TREPR_RS03560	COG0426	domain, Protein
TREPR_RS03565	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
TREPR_RS03570	COG0363	glucosamine-6-phosphate deaminase activity
TREPR_RS03575	COG0165	Argininosuccinate lyase
TREPR_RS03580	COG1487	ribonuclease activity
TREPR_RS03610	COG0137	argininosuccinate synthase activity
TREPR_RS03615	COG1473	amidohydrolase
TREPR_RS03620	COG4585	Histidine kinase
TREPR_RS03625	COG2197	response regulator
TREPR_RS03630	COG0765	amino acid transport
TREPR_RS03635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TREPR_RS03645	COG1126	abc transporter atp-binding protein
TREPR_RS03660	COG0765	amino acid transport
TREPR_RS03670	COG0765	amino acid transport
TREPR_RS03675	COG1126	abc transporter atp-binding protein
TREPR_RS03685	COG0655	NAD(P)H dehydrogenase (quinone) activity
TREPR_RS03690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TREPR_RS03695	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TREPR_RS03700	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TREPR_RS03710	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TREPR_RS03715	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
TREPR_RS03730	COG1175	transmembrane transport
TREPR_RS03735	COG0584	glycerophosphoryl diester phosphodiesterase
TREPR_RS03760	COG2843	Capsule synthesis protein
TREPR_RS03770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TREPR_RS03775	COG3051	citrate lyase alpha subunit
TREPR_RS03785	COG3052	prosthetic group binding
TREPR_RS03795	COG0583	DNA-binding transcription factor activity
TREPR_RS03810	COG0484	heat shock protein binding
TREPR_RS03815	COG0443	Heat shock 70 kDa protein
TREPR_RS03825	COG2357	RelA SpoT domain protein
TREPR_RS03865	COG1454	alcohol dehydrogenase
TREPR_RS03865	COG1012	belongs to the aldehyde dehydrogenase family
TREPR_RS03880	COG1122	ATPase activity
TREPR_RS03940	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TREPR_RS03950	COG2226	methyltransferase
TREPR_RS03960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TREPR_RS03980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TREPR_RS03985	COG1120	ATPase activity
TREPR_RS03990	COG0747	negative chemotaxis
TREPR_RS03995	COG0601	transmembrane transport
TREPR_RS04000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREPR_RS04005	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS04010	COG1124	(ABC) transporter
TREPR_RS04020	COG0714	Associated with various cellular activities
TREPR_RS04055	COG1193	negative regulation of DNA recombination
TREPR_RS04060	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TREPR_RS04065	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TREPR_RS04115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TREPR_RS04120	COG1346	cytolysis
TREPR_RS04150	COG4115	mRNA cleavage
TREPR_RS04165	COG0495	leucyl-tRNA aminoacylation
TREPR_RS04170	COG0477	Major facilitator Superfamily
TREPR_RS04180	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TREPR_RS04195	COG3842	ATPase activity
TREPR_RS04200	COG1178	ABC-type Fe3 transport system permease component
TREPR_RS04210	COG1691	(AIR) carboxylase
TREPR_RS04215	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
TREPR_RS04220	COG1606	tRNA processing
TREPR_RS04235	COG0778	Nitroreductase
TREPR_RS04240	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TREPR_RS04255	COG0107	imidazoleglycerol-phosphate synthase activity
TREPR_RS04260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TREPR_RS04260	COG0140	phosphoribosyl-ATP diphosphatase activity
TREPR_RS04265	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TREPR_RS04270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TREPR_RS04275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TREPR_RS04285	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TREPR_RS04300	COG0326	Molecular chaperone. Has ATPase activity
TREPR_RS04330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TREPR_RS04350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TREPR_RS04355	COG1121	(ABC) transporter
TREPR_RS04395	COG1854	S-ribosylhomocysteine lyase activity
TREPR_RS04450	COG3851	Histidine kinase
TREPR_RS04455	COG2197	response regulator
TREPR_RS04475	COG0792	nuclease activity
TREPR_RS04485	COG2257	FlhB HrpN YscU SpaS Family
TREPR_RS04495	COG0335	large ribosomal subunit rRNA binding
TREPR_RS04500	COG0336	Belongs to the RNA methyltransferase TrmD family
TREPR_RS04505	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TREPR_RS04515	COG0228	four-way junction DNA binding
TREPR_RS04525	COG5002	protein histidine kinase activity
TREPR_RS04525	COG0784	Response regulator, receiver
TREPR_RS04525	COG2198	Histidine kinase
TREPR_RS04585	COG4166	transmembrane transport
TREPR_RS04595	COG0237	dephospho-CoA kinase activity
TREPR_RS04610	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TREPR_RS04615	COG0285	dihydrofolate synthase activity
TREPR_RS04625	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
TREPR_RS04630	COG1122	ATPase activity
TREPR_RS04635	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TREPR_RS04645	COG2759	Belongs to the formate--tetrahydrofolate ligase family
TREPR_RS04650	COG3404	Formiminotransferase-cyclodeaminase
TREPR_RS04655	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TREPR_RS04685	COG4804	nuclease activity
TREPR_RS04710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TREPR_RS04720	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
TREPR_RS04760	COG3383	formate dehydrogenase (NAD+) activity
TREPR_RS04765	COG0493	'glutamate synthase
TREPR_RS04765	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
TREPR_RS04770	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TREPR_RS04780	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
TREPR_RS04780	COG0493	'glutamate synthase
TREPR_RS04800	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
TREPR_RS04805	COG1126	abc transporter atp-binding protein
TREPR_RS04810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TREPR_RS04835	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TREPR_RS04865	COG3383	formate dehydrogenase (NAD+) activity
TREPR_RS04870	COG3383	formate dehydrogenase (NAD+) activity
TREPR_RS04935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TREPR_RS04935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TREPR_RS04935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TREPR_RS04940	COG0840	transmembrane signaling receptor activity
TREPR_RS04945	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TREPR_RS04950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TREPR_RS04950	COG2205	protein histidine kinase activity
TREPR_RS04955	COG3437	response regulator, receiver
TREPR_RS04965	COG0156	8-amino-7-oxononanoate synthase activity
TREPR_RS04970	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
TREPR_RS04980	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
TREPR_RS05015	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TREPR_RS05020	COG0560	Phosphoserine phosphatase
TREPR_RS05035	COG1692	metallophosphoesterase
TREPR_RS05040	COG3394	polysaccharide catabolic process
TREPR_RS05045	COG4149	molybdate abc transporter
TREPR_RS05050	COG3842	ATPase activity
TREPR_RS05065	COG1418	mRNA catabolic process
TREPR_RS05070	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS05075	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS05085	COG0601	transmembrane transport
TREPR_RS05090	COG4166	transmembrane transport
TREPR_RS05110	COG0667	Aldo Keto reductase
TREPR_RS05120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TREPR_RS05130	COG0534	Mate efflux family protein
TREPR_RS05135	COG1137	ATPase activity
TREPR_RS05160	COG2201	protein-glutamate methylesterase activity
TREPR_RS05165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TREPR_RS05170	COG1774	PSP1 C-terminal conserved region
TREPR_RS05185	COG0739	heme binding
TREPR_RS05195	COG2972	Histidine kinase
TREPR_RS05205	COG4213	ABC transporter substrate-binding protein
TREPR_RS05210	COG4213	ABC transporter substrate-binding protein
TREPR_RS05220	COG4214	carbohydrate transport
TREPR_RS05230	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TREPR_RS05260	COG0800	Aldolase
TREPR_RS05265	COG1414	Transcriptional regulator
TREPR_RS05290	COG4948	Mandelate Racemase Muconate Lactonizing
TREPR_RS05295	COG0513	Belongs to the DEAD box helicase family
TREPR_RS05300	COG2137	regulation of response to DNA damage stimulus
TREPR_RS05310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TREPR_RS05335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TREPR_RS05340	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
TREPR_RS05345	COG0527	aspartate kinase activity
TREPR_RS05350	COG0557	exoribonuclease II activity
TREPR_RS05355	COG0643	Histidine kinase
TREPR_RS05355	COG2198	Histidine kinase
TREPR_RS05360	COG0835	chemotaxis
TREPR_RS05375	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
TREPR_RS05375	COG2213	PTS system mannitol-specific
TREPR_RS05390	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
TREPR_RS05395	COG1105	Belongs to the carbohydrate kinase PfkB family
TREPR_RS05400	COG1063	alcohol dehydrogenase
TREPR_RS05410	COG0251	oxidation-reduction process
TREPR_RS05430	COG3711	transcriptional antiterminator
TREPR_RS05435	COG0561	phosphatase activity
TREPR_RS05445	COG1263	PTS System
TREPR_RS05445	COG2190	(PTS) system
TREPR_RS05445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
TREPR_RS05450	COG0737	Belongs to the 5'-nucleotidase family
TREPR_RS05455	COG2723	6-phospho-beta-galactosidase activity
TREPR_RS05465	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TREPR_RS05475	COG2217	Heavy metal translocating P-type atpase
TREPR_RS05485	COG0659	secondary active sulfate transmembrane transporter activity
TREPR_RS05505	COG0840	transmembrane signaling receptor activity
TREPR_RS05515	COG0217	transcriptional regulatory protein
TREPR_RS05520	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TREPR_RS05525	COG0835	chemotaxis
TREPR_RS05535	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TREPR_RS05540	COG0497	DNA recombination
TREPR_RS05550	COG1132	(ABC) transporter
TREPR_RS05555	COG1132	(ABC) transporter
TREPR_RS05565	COG0840	transmembrane signaling receptor activity
TREPR_RS05590	COG1652	LysM domain
TREPR_RS05595	COG0739	heme binding
TREPR_RS05595	COG0741	lytic transglycosylase activity
TREPR_RS05595	COG1196	nuclear chromosome segregation
TREPR_RS05600	COG1674	ftsk spoiiie
TREPR_RS05610	COG2205	protein histidine kinase activity
TREPR_RS05610	COG0784	Response regulator, receiver
TREPR_RS05620	COG5146	pantothenate kinase activity
TREPR_RS05630	COG3858	chitin binding
TREPR_RS05635	COG0725	ABC transporter, periplasmic molybdate-binding protein
TREPR_RS05640	COG4149	molybdate abc transporter
TREPR_RS05650	COG3585	molybdate ion transport
TREPR_RS05655	COG1695	Transcriptional regulator
TREPR_RS05660	COG5012	cobalamin binding
TREPR_RS05670	COG2205	protein histidine kinase activity
TREPR_RS05670	COG3437	response regulator, receiver
TREPR_RS05670	COG3850	Histidine kinase
TREPR_RS05670	COG4999	Histidine kinase
TREPR_RS05685	COG0646	methionine synthase
TREPR_RS05685	COG1410	methionine synthase
TREPR_RS05725	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
TREPR_RS05730	COG0347	Belongs to the P(II) protein family
TREPR_RS05760	COG1433	Dinitrogenase iron-molybdenum cofactor
TREPR_RS05760	COG0535	radical SAM domain protein
TREPR_RS05775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TREPR_RS05785	COG1546	Belongs to the CinA family
TREPR_RS05785	COG1058	Belongs to the CinA family
TREPR_RS05795	COG0641	radical SAM
TREPR_RS05810	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
TREPR_RS05850	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
TREPR_RS05870	COG1360	Flagellar Motor Protein
TREPR_RS05875	COG1580	Controls the rotational direction of flagella during chemotaxis
TREPR_RS05880	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TREPR_RS05885	COG1776	CheC inhibitor of MCP methylation
TREPR_RS05885	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TREPR_RS05895	COG1338	Plays a role in the flagellum-specific transport system
TREPR_RS05900	COG1987	bacterial-type flagellum assembly
TREPR_RS05905	COG1684	flagellar biosynthetic protein fliR
TREPR_RS05910	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TREPR_RS05935	COG1191	sigma factor activity
TREPR_RS05960	COG0737	Belongs to the 5'-nucleotidase family
TREPR_RS05965	COG0494	nUDIX hydrolase
TREPR_RS06020	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
TREPR_RS06040	COG0534	Mate efflux family protein
TREPR_RS06055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TREPR_RS06065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TREPR_RS06070	COG1362	aminopeptidase activity
TREPR_RS06080	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
TREPR_RS06085	COG0542	response to heat
TREPR_RS06090	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
TREPR_RS06095	COG0708	Exodeoxyribonuclease III
TREPR_RS06115	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
TREPR_RS06120	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TREPR_RS06140	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TREPR_RS06145	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TREPR_RS06170	COG0301	tRNA thio-modification
TREPR_RS06175	COG1104	cysteine desulfurase activity
TREPR_RS06185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TREPR_RS06285	COG2211	Major facilitator Superfamily
TREPR_RS06310	COG0693	protein deglycase activity
TREPR_RS06320	COG1692	metallophosphoesterase
TREPR_RS06345	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TREPR_RS06350	COG0561	phosphatase activity
TREPR_RS06355	COG1192	Involved in chromosome partitioning
TREPR_RS06360	COG1475	DNA binding
TREPR_RS06370	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TREPR_RS06375	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
TREPR_RS06380	COG0105	UTP biosynthetic process
TREPR_RS06400	COG0534	Mate efflux family protein
TREPR_RS06420	COG1373	ATPase (AAA superfamily
TREPR_RS06425	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
TREPR_RS06450	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TREPR_RS06455	COG0840	transmembrane signaling receptor activity
TREPR_RS06480	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TREPR_RS06500	COG1104	cysteine desulfurase activity
TREPR_RS06570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TREPR_RS06580	COG1959	2 iron, 2 sulfur cluster binding
TREPR_RS06585	COG1846	Transcriptional regulator
TREPR_RS06595	COG5002	protein histidine kinase activity
TREPR_RS06600	COG0745	RESPONSE REGULATOR receiver
TREPR_RS06630	COG0436	Aminotransferase
TREPR_RS06635	COG0124	histidyl-tRNA synthetase
TREPR_RS06650	COG1413	lyase activity
TREPR_RS06660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TREPR_RS06670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TREPR_RS06675	COG0571	ribonuclease III activity
TREPR_RS06685	COG0617	tRNA 3'-terminal CCA addition
TREPR_RS06695	COG0360	Binds together with S18 to 16S ribosomal RNA
TREPR_RS06700	COG0629	single-stranded DNA binding
TREPR_RS06705	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TREPR_RS06715	COG0359	binds to the 23S rRNA
TREPR_RS06720	COG0305	Participates in initiation and elongation during chromosome replication
TREPR_RS06735	COG0750	zinc metalloprotease
TREPR_RS06740	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TREPR_RS06745	COG0575	Belongs to the CDS family
TREPR_RS06750	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TREPR_RS06755	COG0233	cytoplasmic translational termination
TREPR_RS06760	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TREPR_RS06765	COG0052	Belongs to the universal ribosomal protein uS2 family
TREPR_RS06770	COG0424	maF-like protein
TREPR_RS06780	COG1132	(ABC) transporter
TREPR_RS06785	COG1132	(ABC) transporter
TREPR_RS06810	COG0538	isocitrate dehydrogenase activity
TREPR_RS06815	COG2017	converts alpha-aldose to the beta-anomer
TREPR_RS06820	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
TREPR_RS06830	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TREPR_RS06835	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TREPR_RS06840	COG1394	ATPase activity, coupled to movement of substances
TREPR_RS06845	COG1269	ATP hydrolysis coupled proton transport
TREPR_RS06855	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TREPR_RS06880	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TREPR_RS06910	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TREPR_RS06915	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TREPR_RS06920	COG1643	Atp-dependent helicase
TREPR_RS06940	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TREPR_RS06950	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TREPR_RS06960	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TREPR_RS06975	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
TREPR_RS07000	COG3830	Belongs to the UPF0237 family
TREPR_RS07005	COG2848	UPF0210 protein
TREPR_RS07015	COG4115	mRNA cleavage
TREPR_RS07060	COG1199	ATP-dependent helicase activity
TREPR_RS07075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TREPR_RS07080	COG1573	uracil-dna glycosylase
TREPR_RS07085	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TREPR_RS07090	COG0438	transferase activity, transferring glycosyl groups
TREPR_RS07105	COG0740	serine-type endopeptidase activity
TREPR_RS07110	COG0544	peptidyl-prolyl cis-trans isomerase activity
TREPR_RS07180	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TREPR_RS07190	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TREPR_RS07195	COG0254	rRNA binding
TREPR_RS07210	COG0275	rRNA processing
TREPR_RS07220	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TREPR_RS07225	COG0772	Belongs to the SEDS family
TREPR_RS07245	COG4974	Belongs to the 'phage' integrase family
TREPR_RS07255	COG0758	DNA mediated transformation
TREPR_RS07260	COG0551	DNA topoisomerase type I activity
TREPR_RS07260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TREPR_RS07265	COG4974	Belongs to the 'phage' integrase family
TREPR_RS07270	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TREPR_RS07275	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TREPR_RS07280	COG1815	bacterial-type flagellum-dependent cell motility
TREPR_RS07295	COG1766	The M ring may be actively involved in energy transduction
TREPR_RS07305	COG1317	bacterial-type flagellum organization
TREPR_RS07310	COG1157	protein secretion by the type III secretion system
TREPR_RS07330	COG1116	anion transmembrane transporter activity
TREPR_RS07350	COG1136	(ABC) transporter
TREPR_RS07350	COG0577	efflux transmembrane transporter activity
TREPR_RS07355	COG1136	(ABC) transporter
TREPR_RS07360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TREPR_RS07385	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
TREPR_RS07410	COG1215	transferase activity, transferring glycosyl groups
TREPR_RS07420	COG0562	UDP-galactopyranose mutase
TREPR_RS07430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TREPR_RS07440	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TREPR_RS07465	COG4953	penicillin-binding protein 1C
TREPR_RS07500	COG0330	HflC and HflK could
TREPR_RS07505	COG0330	HflC and HflK could
TREPR_RS07525	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
TREPR_RS07535	COG0395	ABC-type sugar transport system, permease component
TREPR_RS07540	COG1175	transmembrane transport
TREPR_RS07555	COG1234	tRNA 3'-trailer cleavage
TREPR_RS07560	COG1131	(ABC) transporter
TREPR_RS07590	COG1070	Carbohydrate kinase
TREPR_RS07595	COG2115	Belongs to the xylose isomerase family
TREPR_RS07630	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TREPR_RS07635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
TREPR_RS07650	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TREPR_RS07660	COG2197	response regulator
TREPR_RS07725	COG1705	Flagellar rod assembly protein muramidase FlgJ
TREPR_RS07725	COG1388	LysM domain
TREPR_RS07735	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TREPR_RS07740	COG1722	exodeoxyribonuclease VII activity
TREPR_RS07745	COG1570	exodeoxyribonuclease VII activity
TREPR_RS07750	COG0731	radical SAM domain protein
TREPR_RS07765	COG2226	methyltransferase
TREPR_RS07770	COG1181	Belongs to the D-alanine--D-alanine ligase family
TREPR_RS07775	COG0860	N-Acetylmuramoyl-L-alanine amidase
TREPR_RS07790	COG2357	RelA SpoT domain protein
TREPR_RS07795	COG3437	response regulator, receiver
TREPR_RS07805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TREPR_RS07810	COG0126	phosphoglycerate kinase activity
TREPR_RS07815	COG0149	triose-phosphate isomerase activity
TREPR_RS07825	COG0372	Belongs to the citrate synthase family
TREPR_RS07835	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TREPR_RS07850	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TREPR_RS07855	COG2610	gluconate transmembrane transporter activity
TREPR_RS07865	COG2226	methyltransferase
TREPR_RS07915	COG0601	transmembrane transport
TREPR_RS07920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREPR_RS07925	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS07930	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS07935	COG1363	Peptidase, m42
TREPR_RS07955	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TREPR_RS07995	COG0564	pseudouridine synthase activity
TREPR_RS08005	COG1561	YicC-like family, N-terminal region
TREPR_RS08010	COG1102	Psort location Cytoplasmic, score
TREPR_RS08045	COG0438	transferase activity, transferring glycosyl groups
TREPR_RS08050	COG0706	membrane insertase activity
TREPR_RS08060	COG0706	membrane insertase activity
TREPR_RS08075	COG0706	membrane insertase activity
TREPR_RS08085	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
TREPR_RS08110	COG3328	transposase activity
TREPR_RS08130	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TREPR_RS08135	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
TREPR_RS08140	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TREPR_RS08160	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
TREPR_RS08180	COG0110	maltose O-acetyltransferase activity
TREPR_RS08235	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TREPR_RS08240	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TREPR_RS08245	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
TREPR_RS08245	COG0028	Belongs to the TPP enzyme family
TREPR_RS08260	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TREPR_RS08270	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
TREPR_RS08285	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TREPR_RS08290	COG1086	Polysaccharide biosynthesis protein
TREPR_RS08310	COG0653	protein targeting
TREPR_RS08330	COG0494	nUDIX hydrolase
TREPR_RS08350	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TREPR_RS08360	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
TREPR_RS08365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TREPR_RS08375	COG0539	negative regulation of cytoplasmic translation
TREPR_RS08395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TREPR_RS08400	COG2011	ABC-type metal ion transport system permease component
TREPR_RS08405	COG1464	Belongs to the NlpA lipoprotein family
TREPR_RS08410	COG1473	amidohydrolase
TREPR_RS08420	COG0772	Belongs to the SEDS family
TREPR_RS08425	COG0768	penicillin binding
TREPR_RS08440	COG1077	Cell shape determining protein MreB Mrl
TREPR_RS08460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TREPR_RS08465	COG0358	DNA primase activity
TREPR_RS08475	COG1234	tRNA 3'-trailer cleavage
TREPR_RS08500	COG2169	Transcriptional regulator
TREPR_RS08505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TREPR_RS08520	COG1595	DNA-templated transcription, initiation
TREPR_RS08555	COG2197	response regulator
TREPR_RS08620	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TREPR_RS08635	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
TREPR_RS08640	COG1196	nuclear chromosome segregation
TREPR_RS08670	COG3328	transposase activity
TREPR_RS08735	COG0574	Belongs to the PEP-utilizing enzyme family
TREPR_RS08735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TREPR_RS08755	COG0166	Belongs to the GPI family
TREPR_RS08760	COG1438	arginine binding
TREPR_RS08775	COG1193	negative regulation of DNA recombination
TREPR_RS08780	COG1162	GTPase activity
TREPR_RS08785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TREPR_RS08800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TREPR_RS08820	COG1872	DUF167
TREPR_RS08850	COG2204	response regulator
TREPR_RS08855	COG5002	protein histidine kinase activity
TREPR_RS08860	COG0477	Major facilitator Superfamily
TREPR_RS08870	COG1366	Belongs to the anti-sigma-factor antagonist family
TREPR_RS08875	COG2208	phosphoserine phosphatase activity
TREPR_RS08880	COG0470	DNA polymerase III
TREPR_RS08885	COG1286	toxin biosynthetic process
TREPR_RS08890	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TREPR_RS08895	COG0431	NADPH-dependent FMN reductase
TREPR_RS08905	COG3706	GGDEF domain
TREPR_RS08920	COG0017	Asparaginyl-tRNA synthetase
TREPR_RS08925	COG1686	Belongs to the peptidase S11 family
TREPR_RS08935	COG0739	heme binding
TREPR_RS08945	COG0768	penicillin binding
TREPR_RS08955	COG4974	Belongs to the 'phage' integrase family
TREPR_RS09080	COG4221	oxidoreductase activity
TREPR_RS09085	COG3328	transposase activity
TREPR_RS09145	COG3328	transposase activity
TREPR_RS09165	COG1253	flavin adenine dinucleotide binding
TREPR_RS09180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TREPR_RS09195	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TREPR_RS09260	COG0601	transmembrane transport
TREPR_RS09265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREPR_RS09270	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS09275	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS09280	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TREPR_RS09290	COG0297	glycogen (starch) synthase activity
TREPR_RS09300	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
TREPR_RS09495	COG4536	flavin adenine dinucleotide binding
TREPR_RS09500	COG0494	nUDIX hydrolase
TREPR_RS09520	COG0784	Response regulator, receiver
TREPR_RS09520	COG2205	protein histidine kinase activity
TREPR_RS09525	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
TREPR_RS09535	COG0494	nUDIX hydrolase
TREPR_RS09540	COG3328	transposase activity
TREPR_RS09680	COG0587	DNA-directed DNA polymerase activity
TREPR_RS09695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TREPR_RS09735	COG2197	response regulator
TREPR_RS09805	COG0657	acetylesterase activity
TREPR_RS09820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TREPR_RS09825	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TREPR_RS09845	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TREPR_RS09845	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TREPR_RS09845	COG0674	pyruvate-flavodoxin oxidoreductase activity
TREPR_RS09845	COG1013	pyruvate-flavodoxin oxidoreductase activity
TREPR_RS09855	COG0438	transferase activity, transferring glycosyl groups
TREPR_RS09880	COG1840	ABC-type Fe3 transport system, periplasmic component
TREPR_RS09920	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
TREPR_RS09930	COG1609	Transcriptional regulator
TREPR_RS09940	COG1285	pathogenesis
TREPR_RS09945	COG3956	TIGRFAM MazG family protein
TREPR_RS09950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TREPR_RS09955	COG0193	aminoacyl-tRNA hydrolase activity
TREPR_RS09960	COG3345	alpha-galactosidase
TREPR_RS09965	COG0517	IMP dehydrogenase activity
TREPR_RS09965	COG1227	inorganic diphosphatase activity
TREPR_RS09970	COG0789	Transcriptional regulator
TREPR_RS09975	COG2801	Transposase and inactivated derivatives
TREPR_RS09995	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS10000	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS10005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREPR_RS10010	COG0601	transmembrane transport
TREPR_RS10015	COG0747	negative chemotaxis
TREPR_RS10035	COG0740	serine-type endopeptidase activity
TREPR_RS10040	COG1058	Belongs to the CinA family
TREPR_RS10040	COG1546	Belongs to the CinA family
TREPR_RS10055	COG0815	Transfers the fatty acyl group on membrane lipoproteins
TREPR_RS10060	COG0776	regulation of translation
TREPR_RS10065	COG0268	Binds directly to 16S ribosomal RNA
TREPR_RS10070	COG0698	ribose 5-phosphate isomerase
TREPR_RS10075	COG1321	iron dependent repressor
TREPR_RS10080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TREPR_RS10080	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
TREPR_RS10085	COG0101	tRNA pseudouridine synthase activity
TREPR_RS10095	COG0736	holo-[acyl-carrier-protein] synthase activity
TREPR_RS10105	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
TREPR_RS10110	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TREPR_RS10155	COG0802	atpase or kinase
TREPR_RS10160	COG1214	PFAM Peptidase M22, glycoprotease
TREPR_RS10165	COG3437	response regulator, receiver
TREPR_RS10165	COG2770	Histidine kinase
TREPR_RS10175	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
TREPR_RS10180	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TREPR_RS10255	COG2801	Transposase and inactivated derivatives
TREPR_RS10435	COG2197	response regulator
TREPR_RS10505	COG2116	formate transmembrane transporter activity
TREPR_RS10515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TREPR_RS10530	COG0280	phosphate acetyltransferase
TREPR_RS10540	COG0574	Belongs to the PEP-utilizing enzyme family
TREPR_RS10540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TREPR_RS10550	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TREPR_RS10560	COG0542	response to heat
TREPR_RS10565	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TREPR_RS10570	COG1205	dead DEAH box helicase
TREPR_RS10570	COG1111	helicase
TREPR_RS10585	COG0632	four-way junction helicase activity
TREPR_RS10595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TREPR_RS10675	COG2255	four-way junction helicase activity
TREPR_RS10680	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TREPR_RS10695	COG2379	hydroxypyruvate reductase
TREPR_RS10710	COG0295	cytidine deaminase activity
TREPR_RS10720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TREPR_RS10730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TREPR_RS10745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TREPR_RS10745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TREPR_RS10750	COG1373	ATPase (AAA superfamily
TREPR_RS10770	COG0564	pseudouridine synthase activity
TREPR_RS10780	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS10785	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS10790	COG0601	transmembrane transport
TREPR_RS10795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREPR_RS10800	COG0006	proline dipeptidase activity
TREPR_RS10805	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
TREPR_RS10820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TREPR_RS10820	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TREPR_RS10820	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TREPR_RS10830	COG0505	Belongs to the CarA family
TREPR_RS10835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TREPR_RS10845	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TREPR_RS10855	COG1136	(ABC) transporter
TREPR_RS10870	COG0552	protein localization to endoplasmic reticulum
TREPR_RS10880	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TREPR_RS10900	COG0756	dUTP diphosphatase activity
TREPR_RS10905	COG1185	polyribonucleotide nucleotidyltransferase activity
TREPR_RS10925	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TREPR_RS10930	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TREPR_RS10955	COG1449	Belongs to the glycosyl hydrolase 57 family
TREPR_RS10960	COG4657	Part of a membrane complex involved in electron transport
TREPR_RS10975	COG4658	electron transport chain
TREPR_RS10995	COG0564	pseudouridine synthase activity
TREPR_RS11000	COG0737	Belongs to the 5'-nucleotidase family
TREPR_RS11025	COG0617	tRNA 3'-terminal CCA addition
TREPR_RS11035	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TREPR_RS11060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TREPR_RS11075	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
TREPR_RS11095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TREPR_RS11110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TREPR_RS11120	COG1747	RNA polymerase binding
TREPR_RS11120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TREPR_RS11130	COG0343	queuine tRNA-ribosyltransferase activity
TREPR_RS11150	COG2205	protein histidine kinase activity
TREPR_RS11150	COG0784	Response regulator, receiver
TREPR_RS11150	COG5002	protein histidine kinase activity
TREPR_RS11160	COG2182	Extracellular solute-binding protein
TREPR_RS11170	COG0840	transmembrane signaling receptor activity
TREPR_RS11175	COG3437	response regulator, receiver
TREPR_RS11195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TREPR_RS11205	COG1116	anion transmembrane transporter activity
TREPR_RS11205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TREPR_RS11210	COG4120	Belongs to the binding-protein-dependent transport system permease family
TREPR_RS11240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TREPR_RS11245	COG1480	7TM receptor with intracellular HD hydrolase
TREPR_RS11250	COG1702	phosphate starvation-inducible protein PhoH
TREPR_RS11255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TREPR_RS11275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TREPR_RS11315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TREPR_RS11320	COG1120	ATPase activity
TREPR_RS11340	COG1136	(ABC) transporter
TREPR_RS11350	COG0840	transmembrane signaling receptor activity
TREPR_RS11380	COG2201	protein-glutamate methylesterase activity
TREPR_RS11390	COG0840	transmembrane signaling receptor activity
TREPR_RS11410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TREPR_RS11415	COG3437	response regulator, receiver
TREPR_RS11415	COG0784	Response regulator, receiver
TREPR_RS11420	COG1671	Belongs to the UPF0178 family
TREPR_RS11430	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
TREPR_RS11440	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TREPR_RS11450	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TREPR_RS11485	COG0066	3-isopropylmalate dehydratase activity
TREPR_RS11525	COG1215	transferase activity, transferring glycosyl groups
TREPR_RS11530	COG0215	cysteine-tRNA ligase activity
TREPR_RS11550	COG1305	Transglutaminase-like
TREPR_RS11555	COG0528	UMP kinase activity
TREPR_RS11560	COG0205	6-phosphofructokinase activity
TREPR_RS11565	COG0514	ATP-dependent DNA helicase (RecQ)
TREPR_RS11570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TREPR_RS11590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TREPR_RS11590	COG0517	IMP dehydrogenase activity
TREPR_RS11590	COG0617	tRNA 3'-terminal CCA addition
TREPR_RS11595	COG2186	Transcriptional regulator
TREPR_RS11600	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
TREPR_RS11605	COG2723	6-phospho-beta-galactosidase activity
TREPR_RS11620	COG0395	ABC-type sugar transport system, permease component
TREPR_RS11625	COG4989	oxidoreductase activity
TREPR_RS11630	COG0129	dihydroxy-acid dehydratase activity
TREPR_RS11635	COG2723	6-phospho-beta-galactosidase activity
TREPR_RS11640	COG3250	beta-galactosidase activity
TREPR_RS11645	COG0395	ABC-type sugar transport system, permease component
TREPR_RS11700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TREPR_RS11710	COG2205	protein histidine kinase activity
TREPR_RS11710	COG0784	Response regulator, receiver
TREPR_RS11715	COG1475	DNA binding
TREPR_RS11725	COG0431	NADPH-dependent FMN reductase
TREPR_RS11735	COG0741	lytic transglycosylase activity
TREPR_RS11735	COG0739	heme binding
TREPR_RS11735	COG1196	nuclear chromosome segregation
TREPR_RS11750	COG0655	NAD(P)H dehydrogenase (quinone) activity
TREPR_RS11755	COG2208	phosphoserine phosphatase activity
TREPR_RS11755	COG2770	Histidine kinase
TREPR_RS11760	COG2814	Major facilitator Superfamily
TREPR_RS11775	COG0525	valine-tRNA ligase activity
TREPR_RS11780	COG0534	Mate efflux family protein
TREPR_RS11795	COG0523	cobalamin synthesis protein
TREPR_RS11805	COG0583	DNA-binding transcription factor activity
TREPR_RS11815	COG2814	Major facilitator Superfamily
TREPR_RS11830	COG5012	cobalamin binding
TREPR_RS11855	COG3835	regulator
TREPR_RS11860	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TREPR_RS11865	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TREPR_RS11870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TREPR_RS11875	COG1862	Preprotein translocase
TREPR_RS11890	COG1592	Rubrerythrin
TREPR_RS11935	COG0601	transmembrane transport
TREPR_RS11945	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS11955	COG3842	ATPase activity
TREPR_RS11960	COG1177	transmembrane transport
TREPR_RS11970	COG0513	Belongs to the DEAD box helicase family
TREPR_RS11975	COG0488	(ABC) transporter
TREPR_RS11985	COG1879	ABC-type sugar transport system periplasmic component
TREPR_RS11990	COG1172	Belongs to the binding-protein-dependent transport system permease family
TREPR_RS11995	COG1129	ABC transporter
TREPR_RS12015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TREPR_RS12025	COG1486	melibiose metabolic process
TREPR_RS12030	COG1840	ABC-type Fe3 transport system, periplasmic component
TREPR_RS12035	COG1178	ABC-type Fe3 transport system permease component
TREPR_RS12040	COG3842	ATPase activity
TREPR_RS12055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TREPR_RS12060	COG2890	protein-(glutamine-N5) methyltransferase activity
TREPR_RS12065	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TREPR_RS12080	COG0202	RNA polymerase activity
TREPR_RS12085	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TREPR_RS12105	COG0200	Binds to the 23S rRNA
TREPR_RS12110	COG1841	ribosomal large subunit assembly
TREPR_RS12115	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TREPR_RS12120	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TREPR_RS12125	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TREPR_RS12130	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TREPR_RS12140	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TREPR_RS12145	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TREPR_RS12150	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TREPR_RS12155	COG0255	Belongs to the universal ribosomal protein uL29 family
TREPR_RS12170	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TREPR_RS12180	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TREPR_RS12185	COG0089	rRNA binding
TREPR_RS12190	COG0088	Forms part of the polypeptide exit tunnel
TREPR_RS12195	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TREPR_RS12200	COG0051	transcription antitermination factor activity, RNA binding
TREPR_RS12205	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TREPR_RS12235	COG3842	ATPase activity
TREPR_RS12240	COG1176	ABC-type spermidine putrescine transport system, permease component I
TREPR_RS12245	COG1177	transmembrane transport
TREPR_RS12275	COG1164	Oligoendopeptidase f
TREPR_RS12285	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TREPR_RS12300	COG1136	(ABC) transporter
TREPR_RS12305	COG0577	efflux transmembrane transporter activity
TREPR_RS12305	COG1136	(ABC) transporter
TREPR_RS12320	COG3470	protein probably involved in high-affinity Fe2 transport
TREPR_RS12325	COG0672	)-iron permease
TREPR_RS12350	COG1175	transmembrane transport
TREPR_RS12370	COG4115	mRNA cleavage
TREPR_RS12430	COG1136	(ABC) transporter
TREPR_RS12435	COG0577	efflux transmembrane transporter activity
TREPR_RS12500	COG3549	Plasmid maintenance system killer
TREPR_RS12505	COG3093	addiction module antidote protein HigA
TREPR_RS12520	COG0561	phosphatase activity
TREPR_RS12550	COG1459	type II secretion system
TREPR_RS12615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TREPR_RS12630	COG1132	(ABC) transporter
TREPR_RS12640	COG0747	negative chemotaxis
TREPR_RS12650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREPR_RS12655	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS12660	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS12665	COG4948	Mandelate Racemase Muconate Lactonizing
TREPR_RS12680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TREPR_RS12685	COG0564	pseudouridine synthase activity
TREPR_RS12695	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TREPR_RS12700	COG3457	Alanine racemase
TREPR_RS12705	COG3804	dihydrodipicolinate reductase
TREPR_RS12715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TREPR_RS12725	COG5012	cobalamin binding
TREPR_RS12735	COG1757	Na H antiporter
TREPR_RS12740	COG0737	Belongs to the 5'-nucleotidase family
TREPR_RS12745	COG0561	phosphatase activity
TREPR_RS12750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TREPR_RS12755	COG0765	amino acid transport
TREPR_RS12760	COG1126	abc transporter atp-binding protein
TREPR_RS12775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TREPR_RS12775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TREPR_RS12795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TREPR_RS12795	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TREPR_RS12810	COG0321	lipoyl(octanoyl) transferase activity
TREPR_RS12810	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
TREPR_RS12825	COG2272	Belongs to the type-B carboxylesterase lipase family
TREPR_RS12830	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS12835	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS12845	COG0601	transmembrane transport
TREPR_RS12850	COG0747	negative chemotaxis
TREPR_RS12885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TREPR_RS12890	COG4569	acetaldehyde dehydrogenase (acetylating) activity
TREPR_RS12900	COG2267	carboxylic ester hydrolase activity
TREPR_RS12910	COG2186	Transcriptional regulator
TREPR_RS12915	COG1082	Xylose isomerase domain protein TIM barrel
TREPR_RS12920	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TREPR_RS12940	COG3959	Transketolase, thiamine diphosphate binding domain
TREPR_RS12945	COG3958	Transketolase
TREPR_RS12950	COG2084	Dehydrogenase
TREPR_RS12995	COG1473	amidohydrolase
TREPR_RS13055	COG2301	Belongs to the HpcH HpaI aldolase family
TREPR_RS13060	COG3052	prosthetic group binding
TREPR_RS13065	COG1473	amidohydrolase
TREPR_RS13080	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
TREPR_RS13085	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TREPR_RS13090	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TREPR_RS13100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TREPR_RS13105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TREPR_RS13125	COG0511	ligase activity, forming carbon-carbon bonds
TREPR_RS13130	COG0439	Biotin carboxylase
TREPR_RS13135	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TREPR_RS13140	COG0825	malonyl-CoA metabolic process
TREPR_RS13150	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TREPR_RS13155	COG2086	electron transfer activity
TREPR_RS13175	COG0784	Response regulator, receiver
TREPR_RS13175	COG2198	Histidine kinase
TREPR_RS13175	COG5002	protein histidine kinase activity
TREPR_RS13195	COG0784	Response regulator, receiver
TREPR_RS13195	COG5002	protein histidine kinase activity
TREPR_RS13195	COG2198	Histidine kinase
TREPR_RS13200	COG5002	protein histidine kinase activity
TREPR_RS13200	COG0784	Response regulator, receiver
TREPR_RS13200	COG2205	protein histidine kinase activity
TREPR_RS13205	COG2205	protein histidine kinase activity
TREPR_RS13205	COG5002	protein histidine kinase activity
TREPR_RS13205	COG0784	Response regulator, receiver
TREPR_RS13220	COG3437	response regulator, receiver
TREPR_RS13220	COG2205	protein histidine kinase activity
TREPR_RS13220	COG4999	Histidine kinase
TREPR_RS13220	COG3850	Histidine kinase
TREPR_RS13280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
TREPR_RS13285	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
TREPR_RS13290	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
TREPR_RS13295	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
TREPR_RS13300	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TREPR_RS13305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TREPR_RS13310	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TREPR_RS13325	COG0626	cystathionine gamma-synthase activity
TREPR_RS13335	COG0521	Mo-molybdopterin cofactor biosynthetic process
TREPR_RS13345	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TREPR_RS13360	COG2089	acid synthase
TREPR_RS13365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TREPR_RS13370	COG0024	Methionine aminopeptidase
TREPR_RS13375	COG0484	heat shock protein binding
TREPR_RS13390	COG1394	ATPase activity, coupled to movement of substances
TREPR_RS13395	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TREPR_RS13410	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
TREPR_RS13415	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TREPR_RS13430	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TREPR_RS13435	COG2814	Major facilitator Superfamily
TREPR_RS13445	COG1846	Transcriptional regulator
TREPR_RS13450	COG0037	tRNA processing
TREPR_RS13465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TREPR_RS13495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TREPR_RS13520	COG0436	Aminotransferase
TREPR_RS13530	COG1487	ribonuclease activity
TREPR_RS13535	COG0514	ATP-dependent DNA helicase (RecQ)
TREPR_RS13550	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TREPR_RS13560	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
TREPR_RS13560	COG0662	Cupin 2, conserved barrel domain protein
TREPR_RS13580	COG1022	Amp-dependent synthetase and ligase
TREPR_RS13585	COG1355	regulation of microtubule-based process
TREPR_RS13595	COG1472	Belongs to the glycosyl hydrolase 3 family
TREPR_RS13600	COG0564	pseudouridine synthase activity
TREPR_RS13615	COG1811	Na channel or pump
TREPR_RS13660	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TREPR_RS13665	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TREPR_RS13685	COG1269	ATP hydrolysis coupled proton transport
TREPR_RS13710	COG1910	domain protein
TREPR_RS13720	COG1136	(ABC) transporter
TREPR_RS13725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
TREPR_RS13775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TREPR_RS13780	COG1120	ATPase activity
TREPR_RS13785	COG0517	IMP dehydrogenase activity
TREPR_RS13810	COG0683	leucine binding
TREPR_RS13830	COG0668	transmembrane transport
TREPR_RS13835	COG0662	Cupin 2, conserved barrel domain protein
TREPR_RS13840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TREPR_RS13875	COG0006	proline dipeptidase activity
TREPR_RS13885	COG1234	tRNA 3'-trailer cleavage
TREPR_RS13890	COG1639	'signal transduction protein
TREPR_RS13905	COG0322	excinuclease ABC activity
TREPR_RS13975	COG0191	fructose-bisphosphate aldolase activity
TREPR_RS13990	COG0671	phosphoesterase, PA-phosphatase related
TREPR_RS13995	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TREPR_RS14005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TREPR_RS14010	COG0537	adenosine 5'-monophosphoramidase activity
TREPR_RS14015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TREPR_RS14030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TREPR_RS14035	COG0012	GTP binding
TREPR_RS14045	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
TREPR_RS14050	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TREPR_RS14065	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TREPR_RS14075	COG1584	GPR1 FUN34 yaaH family protein
TREPR_RS14085	COG1489	DNA binding
TREPR_RS14095	COG0564	pseudouridine synthase activity
TREPR_RS14100	COG0784	Response regulator, receiver
TREPR_RS14100	COG2205	protein histidine kinase activity
TREPR_RS14100	COG5002	protein histidine kinase activity
TREPR_RS14115	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
TREPR_RS14155	COG0778	Nitroreductase
TREPR_RS14165	COG1959	2 iron, 2 sulfur cluster binding
TREPR_RS14190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TREPR_RS14205	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TREPR_RS14225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TREPR_RS14230	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TREPR_RS14235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TREPR_RS14235	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TREPR_RS14240	COG1329	Transcriptional regulator
TREPR_RS14250	COG0534	Mate efflux family protein
TREPR_RS14300	COG3328	transposase activity
TREPR_RS14315	COG2508	Transcriptional regulator
TREPR_RS14335	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
TREPR_RS14335	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TREPR_RS14380	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TREPR_RS14385	COG0825	malonyl-CoA metabolic process
TREPR_RS14395	COG2199	diguanylate cyclase activity
TREPR_RS14395	COG2203	Gaf domain
TREPR_RS14410	COG0440	acetolactate synthase activity
TREPR_RS14415	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TREPR_RS14420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TREPR_RS14425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TREPR_RS14430	COG0473	3-isopropylmalate dehydrogenase activity
TREPR_RS14435	COG0129	dihydroxy-acid dehydratase activity
TREPR_RS14440	COG0028	Belongs to the TPP enzyme family
TREPR_RS14445	COG1477	protein flavinylation
TREPR_RS14460	COG5341	Protein conserved in bacteria
TREPR_RS14465	COG1966	Carbon starvation protein
TREPR_RS14480	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TREPR_RS14485	COG0765	amino acid transport
TREPR_RS14490	COG0765	amino acid transport
TREPR_RS14495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TREPR_RS14500	COG1126	abc transporter atp-binding protein
TREPR_RS14520	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
TREPR_RS14530	COG0243	molybdopterin cofactor binding
TREPR_RS14540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TREPR_RS14545	COG0765	amino acid transport
TREPR_RS14550	COG1126	abc transporter atp-binding protein
TREPR_RS14610	COG0006	proline dipeptidase activity
TREPR_RS14615	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
TREPR_RS14620	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
TREPR_RS14625	COG0747	negative chemotaxis
TREPR_RS14630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREPR_RS14635	COG0601	transmembrane transport
TREPR_RS14640	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS14645	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS14650	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TREPR_RS14655	COG0085	RNA polymerase activity
TREPR_RS14665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TREPR_RS14670	COG0081	regulation of translation
TREPR_RS14675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TREPR_RS14680	COG0250	Participates in transcription elongation, termination and antitermination
TREPR_RS14685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TREPR_RS14695	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TREPR_RS14710	COG2205	protein histidine kinase activity
TREPR_RS14710	COG0784	Response regulator, receiver
TREPR_RS14735	COG1475	DNA binding
TREPR_RS14765	COG0587	DNA-directed DNA polymerase activity
TREPR_RS14780	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TREPR_RS14785	COG1122	ATPase activity
TREPR_RS14795	COG2003	Belongs to the UPF0758 family
TREPR_RS14940	COG1943	Transposase
TREPR_RS14970	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TREPR_RS14995	COG0563	adenylate kinase activity
TREPR_RS15010	COG2843	Capsule synthesis protein
TREPR_RS15015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TREPR_RS15025	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TREPR_RS15040	COG1733	regulation of RNA biosynthetic process
TREPR_RS15065	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
TREPR_RS15080	COG0626	cystathionine gamma-synthase activity
TREPR_RS15090	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TREPR_RS15100	COG1473	amidohydrolase
TREPR_RS15105	COG0747	negative chemotaxis
TREPR_RS15110	COG1362	aminopeptidase activity
TREPR_RS15120	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS15125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREPR_RS15130	COG0601	transmembrane transport
TREPR_RS15170	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
TREPR_RS15210	COG0714	Associated with various cellular activities
TREPR_RS15240	COG0534	Mate efflux family protein
TREPR_RS15245	COG0546	phosphoglycolate phosphatase activity
TREPR_RS15250	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
TREPR_RS15255	COG2078	PFAM AMMECR1 domain protein
TREPR_RS15260	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
TREPR_RS15265	COG1687	branched-chain amino acid
TREPR_RS15270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TREPR_RS15330	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TREPR_RS15355	COG0148	phosphopyruvate hydratase activity
TREPR_RS15360	COG3657	addiction module killer protein
TREPR_RS15365	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TREPR_RS15385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TREPR_RS15390	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TREPR_RS15400	COG1639	'signal transduction protein
TREPR_RS15405	COG0724	RNA recognition motif
TREPR_RS15425	COG4864	UPF0365 protein
TREPR_RS15440	COG5012	cobalamin binding
TREPR_RS15460	COG0210	DNA helicase
TREPR_RS15470	COG4399	Belongs to the UPF0754 family
TREPR_RS15485	COG1959	2 iron, 2 sulfur cluster binding
TREPR_RS15515	COG2801	Transposase and inactivated derivatives
TREPR_RS15530	COG0423	glycine-tRNA ligase activity
TREPR_RS15540	COG0534	Mate efflux family protein
TREPR_RS15550	COG0419	ATPase involved in DNA repair
TREPR_RS15555	COG0420	3'-5' exonuclease activity
TREPR_RS15570	COG4211	Belongs to the binding-protein-dependent transport system permease family
TREPR_RS15575	COG1132	(ABC) transporter
TREPR_RS15590	COG0765	amino acid transport
TREPR_RS15595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TREPR_RS15605	COG0656	L-ascorbic acid biosynthetic process
TREPR_RS15620	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
TREPR_RS15625	COG0142	geranyltranstransferase activity
TREPR_RS15635	COG1196	nuclear chromosome segregation
TREPR_RS15635	COG0739	heme binding
TREPR_RS15635	COG0741	lytic transglycosylase activity
TREPR_RS15645	COG0446	pyridine nucleotide-disulphide oxidoreductase
TREPR_RS15665	COG0747	negative chemotaxis
TREPR_RS15670	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS15675	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS15680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREPR_RS15685	COG0601	transmembrane transport
TREPR_RS15700	COG0673	inositol 2-dehydrogenase activity
TREPR_RS15705	COG0840	transmembrane signaling receptor activity
TREPR_RS15710	COG0784	Response regulator, receiver
TREPR_RS15710	COG5002	protein histidine kinase activity
TREPR_RS15710	COG2198	Histidine kinase
TREPR_RS15730	COG1078	dGTPase activity
TREPR_RS15755	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
TREPR_RS15760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TREPR_RS15765	COG5000	phosphorelay sensor kinase activity
TREPR_RS15785	COG0475	glutathione-regulated potassium exporter activity
TREPR_RS15810	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS15815	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS15820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREPR_RS15825	COG0601	transmembrane transport
TREPR_RS15835	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TREPR_RS15840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TREPR_RS15845	COG0248	Ppx GppA phosphatase
TREPR_RS15855	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TREPR_RS15865	COG0442	prolyl-tRNA aminoacylation
TREPR_RS15880	COG0483	inositol monophosphate 1-phosphatase activity
TREPR_RS15885	COG3842	ATPase activity
TREPR_RS15905	COG1070	Carbohydrate kinase
TREPR_RS15920	COG1609	Transcriptional regulator
TREPR_RS15935	COG0556	nucleotide-excision repair
TREPR_RS15965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TREPR_RS15970	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TREPR_RS15975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TREPR_RS15980	COG0542	response to heat
TREPR_RS15990	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TREPR_RS16005	COG0436	Aminotransferase
TREPR_RS16010	COG1959	2 iron, 2 sulfur cluster binding
TREPR_RS16020	COG0626	cystathionine gamma-synthase activity
TREPR_RS16025	COG0626	cystathionine gamma-synthase activity
TREPR_RS16035	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TREPR_RS16035	COG1918	ferrous iron import across plasma membrane
TREPR_RS16090	COG2205	protein histidine kinase activity
TREPR_RS16090	COG0784	Response regulator, receiver
TREPR_RS16090	COG2198	Histidine kinase
TREPR_RS16095	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TREPR_RS16100	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TREPR_RS16125	COG0205	6-phosphofructokinase activity
TREPR_RS16135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TREPR_RS16140	COG1487	ribonuclease activity
TREPR_RS16175	COG4443	Transcriptional Coactivator p15 (PC4)
TREPR_RS16180	COG0328	RNA-DNA hybrid ribonuclease activity
TREPR_RS16195	COG1802	Transcriptional regulator
TREPR_RS16210	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TREPR_RS16215	COG1312	Catalyzes the dehydration of D-mannonate
TREPR_RS16220	COG0246	Mannitol dehydrogenase
TREPR_RS16225	COG1904	glucuronate isomerase
TREPR_RS16230	COG0800	Aldolase
TREPR_RS16235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TREPR_RS16250	COG2217	Heavy metal translocating P-type atpase
TREPR_RS16255	COG2608	mercury ion transmembrane transporter activity
TREPR_RS16265	COG2205	protein histidine kinase activity
TREPR_RS16305	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TREPR_RS16310	COG0037	tRNA processing
TREPR_RS16320	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
TREPR_RS16325	COG1177	transmembrane transport
TREPR_RS16335	COG3842	ATPase activity
TREPR_RS16340	COG1509	lysine 2,3-aminomutase activity
TREPR_RS16355	COG0110	maltose O-acetyltransferase activity
TREPR_RS16360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TREPR_RS16365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TREPR_RS16385	COG0488	(ABC) transporter
TREPR_RS16400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TREPR_RS16435	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TREPR_RS16440	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TREPR_RS16460	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
TREPR_RS16465	COG1120	ATPase activity
TREPR_RS16470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TREPR_RS16490	COG1492	cobalamin metabolic process
TREPR_RS16495	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
TREPR_RS16500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TREPR_RS16505	COG2082	Precorrin-8x methylmutase
TREPR_RS16515	COG1492	cobalamin metabolic process
TREPR_RS16520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TREPR_RS16530	COG1797	cobyrinic acid a,c-diamide synthase activity
TREPR_RS16560	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
TREPR_RS16570	COG4771	TonB-dependent receptor
TREPR_RS16595	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TREPR_RS16600	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TREPR_RS16630	COG0230	Belongs to the bacterial ribosomal protein bL34 family
TREPR_RS16635	COG0594	ribonuclease P activity
TREPR_RS16640	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TREPR_RS16645	COG0706	membrane insertase activity
TREPR_RS16650	COG1847	R3H domain protein
TREPR_RS16665	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
TREPR_RS16670	COG0116	Belongs to the methyltransferase superfamily
TREPR_RS16675	COG1309	transcriptional regulator
TREPR_RS16685	COG0840	transmembrane signaling receptor activity
TREPR_RS16690	COG0840	transmembrane signaling receptor activity
TREPR_RS16695	COG0840	transmembrane signaling receptor activity
TREPR_RS16705	COG0009	L-threonylcarbamoyladenylate synthase
TREPR_RS16710	COG0598	Magnesium transport protein CorA
TREPR_RS16715	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TREPR_RS16715	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TREPR_RS16715	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TREPR_RS16760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREPR_RS16765	COG0444	Belongs to the ABC transporter superfamily
TREPR_RS16770	COG4608	Belongs to the ABC transporter superfamily
TREPR_RS16785	COG0006	proline dipeptidase activity
TREPR_RS16790	COG0243	molybdopterin cofactor binding
TREPR_RS16795	COG0363	glucosamine-6-phosphate deaminase activity
TREPR_RS16800	COG2723	6-phospho-beta-galactosidase activity
TREPR_RS16805	COG2365	Tyrosine phosphatase family
TREPR_RS16810	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TREPR_RS16815	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
TREPR_RS16820	COG1447	Phosphotransferase system cellobiose-specific component IIA
TREPR_RS16825	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
TREPR_RS16825	COG3933	PFAM sigma-54 factor interaction domain-containing protein
TREPR_RS16830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TREPR_RS16835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TREPR_RS16870	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TREPR_RS16880	COG3706	GGDEF domain
TREPR_RS16885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TREPR_RS16885	COG3116	cell division
TREPR_RS16890	COG0084	hydrolase, TatD family'
TREPR_RS16895	COG2197	response regulator
TREPR_RS16900	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TREPR_RS16905	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TREPR_RS16910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TREPR_RS16915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TREPR_RS16920	COG2272	Belongs to the type-B carboxylesterase lipase family
TREPR_RS16935	COG1172	Belongs to the binding-protein-dependent transport system permease family
TREPR_RS16995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TREPR_RS17000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TREPR_RS17005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TREPR_RS17020	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TREPR_RS17025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TREPR_RS17035	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TREPR_RS17050	COG1902	pentaerythritol trinitrate reductase activity
TREPR_RS17050	COG0446	pyridine nucleotide-disulphide oxidoreductase
TREPR_RS17085	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TREPR_RS17090	COG3012	SEC-C Motif Domain Protein
TREPR_RS17095	COG0673	inositol 2-dehydrogenase activity
TREPR_RS17100	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TREPR_RS17105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
TREPR_RS17120	COG1172	Belongs to the binding-protein-dependent transport system permease family
TREPR_RS17125	COG1129	ABC transporter
TREPR_RS17140	COG0673	inositol 2-dehydrogenase activity
TREPR_RS17150	COG3962	Belongs to the TPP enzyme family
TREPR_RS17160	COG1082	Xylose isomerase domain protein TIM barrel
TREPR_RS17165	COG0126	phosphoglycerate kinase activity
TREPR_RS17175	COG0281	malic enzyme
TREPR_RS17185	COG3875	lactate racemase activity
TREPR_RS17195	COG0159	tryptophan synthase activity
TREPR_RS17200	COG0133	tryptophan synthase activity
TREPR_RS17210	COG0134	indole-3-glycerol-phosphate synthase activity
TREPR_RS17215	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TREPR_RS17220	COG0512	Glutamine amidotransferase of anthranilate synthase
TREPR_RS17220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
TREPR_RS17260	COG0482	sulfurtransferase activity
TREPR_RS17270	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
TREPR_RS17275	COG0519	Catalyzes the synthesis of GMP from XMP
TREPR_RS17280	COG0612	Peptidase, M16
TREPR_RS17285	COG0778	Nitroreductase
TREPR_RS17290	COG0596	Alpha beta hydrolase
TREPR_RS17295	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TREPR_RS17300	COG1181	Belongs to the D-alanine--D-alanine ligase family
TREPR_RS17355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TREPR_RS17375	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
TREPR_RS17385	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TREPR_RS17390	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TREPR_RS17400	COG0438	transferase activity, transferring glycosyl groups
TREPR_RS17410	COG0367	asparagine synthase
TREPR_RS17430	COG0546	phosphoglycolate phosphatase activity
TREPR_RS17440	COG3959	Transketolase, thiamine diphosphate binding domain
TREPR_RS17445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TREPR_RS17470	COG1487	ribonuclease activity
TREPR_RS17500	COG1373	ATPase (AAA superfamily
TREPR_RS17520	COG1968	undecaprenyl-diphosphatase activity
TREPR_RS17525	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TREPR_RS17530	COG0443	Heat shock 70 kDa protein
TREPR_RS17535	COG0484	heat shock protein binding
TREPR_RS17540	COG4656	Part of a membrane complex involved in electron transport
TREPR_RS17545	COG4658	electron transport chain
TREPR_RS17550	COG4659	FMN binding
TREPR_RS17555	COG4660	Part of a membrane complex involved in electron transport
TREPR_RS17560	COG4657	Part of a membrane complex involved in electron transport
TREPR_RS17565	COG2878	Part of a membrane complex involved in electron transport
TREPR_RS17575	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TREPR_RS17580	COG0667	Aldo Keto reductase
TREPR_RS17620	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TREPR_RS17630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TREPR_RS17645	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TREPR_RS17665	COG3842	ATPase activity
TREPR_RS17675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TREPR_RS17690	COG0187	DNA topoisomerase II activity
TREPR_RS17720	COG1216	Glycosyl transferase, family 2
TREPR_RS17760	COG1396	sequence-specific DNA binding
TREPR_RS17805	COG0667	Aldo Keto reductase
TREPR_RS17825	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
TREPR_RS17830	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
TREPR_RS17845	COG0463	Glycosyl transferase, family 2
TREPR_RS17920	COG2272	Belongs to the type-B carboxylesterase lipase family
TREPR_RS17925	COG1660	Displays ATPase and GTPase activities
TREPR_RS17940	COG4796	Type ii and iii secretion system protein
TREPR_RS17960	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TREPR_RS18005	COG1051	belongs to the nudix hydrolase family