locus-tag	class	description
DYE50_RS00020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYE50_RS00025	COG0347	Belongs to the P(II) protein family
DYE50_RS00060	COG1051	belongs to the nudix hydrolase family
DYE50_RS00070	COG2382	esterase
DYE50_RS00070	COG3693	PFAM glycoside hydrolase, family 10
DYE50_RS00070	COG3507	Belongs to the glycosyl hydrolase 43 family
DYE50_RS00080	COG3443	Belongs to the bacterial solute-binding protein 9 family
DYE50_RS00080	COG0803	Belongs to the bacterial solute-binding protein 9 family
DYE50_RS00085	COG0523	cobalamin synthesis protein
DYE50_RS00095	COG1304	FMN binding
DYE50_RS00105	COG0348	domain, Protein
DYE50_RS00105	COG3901	Regulator of nitric oxide reductase transcription
DYE50_RS00115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DYE50_RS00135	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DYE50_RS00140	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DYE50_RS00145	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DYE50_RS00150	COG1904	glucuronate isomerase
DYE50_RS00155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DYE50_RS00175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DYE50_RS00190	COG0706	membrane insertase activity
DYE50_RS00195	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DYE50_RS00220	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DYE50_RS00225	COG0592	DNA-directed DNA polymerase activity
DYE50_RS00265	COG0187	DNA topoisomerase II activity
DYE50_RS00270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DYE50_RS00275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYE50_RS00290	COG2207	Transcriptional regulator
DYE50_RS00295	COG0534	Mate efflux family protein
DYE50_RS00300	COG3266	domain, Protein
DYE50_RS00300	COG0515	serine threonine protein kinase
DYE50_RS00310	COG1979	alcohol dehydrogenase
DYE50_RS00325	COG3706	GGDEF domain
DYE50_RS00325	COG5001	Diguanylate cyclase
DYE50_RS00325	COG2203	Gaf domain
DYE50_RS00325	COG4251	negative regulation of phosphorylation
DYE50_RS00355	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DYE50_RS00355	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DYE50_RS00360	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DYE50_RS00385	COG2217	Heavy metal translocating P-type atpase
DYE50_RS00390	COG0640	Transcriptional regulator
DYE50_RS00395	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DYE50_RS00400	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DYE50_RS00435	COG0488	(ABC) transporter
DYE50_RS00445	COG0058	SHG alpha-glucan phosphorylase activity
DYE50_RS00450	COG3706	GGDEF domain
DYE50_RS00455	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DYE50_RS00460	COG2755	lipolytic protein G-D-S-L family
DYE50_RS00465	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DYE50_RS00485	COG1643	Atp-dependent helicase
DYE50_RS00490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DYE50_RS00520	COG2358	TRAP transporter, solute receptor (TAXI family
DYE50_RS00530	COG0326	Molecular chaperone. Has ATPase activity
DYE50_RS00565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DYE50_RS00570	COG3001	Fructosamine kinase
DYE50_RS00575	COG3300	MHYT domain
DYE50_RS00575	COG5001	Diguanylate cyclase
DYE50_RS00580	COG3706	GGDEF domain
DYE50_RS00585	COG0488	(ABC) transporter
DYE50_RS00595	COG0281	malic enzyme
DYE50_RS00620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DYE50_RS00635	COG1674	ftsk spoiiie
DYE50_RS00640	COG2022	thiamine diphosphate biosynthetic process
DYE50_RS00655	COG0616	signal peptide processing
DYE50_RS00690	COG2801	Transposase and inactivated derivatives
DYE50_RS00705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DYE50_RS00715	COG0668	transmembrane transport
DYE50_RS00720	COG0534	Mate efflux family protein
DYE50_RS00740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DYE50_RS00740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DYE50_RS00775	COG1388	LysM domain
DYE50_RS00775	COG0791	NLP P60 protein
DYE50_RS00780	COG0246	Mannitol dehydrogenase
DYE50_RS00785	COG1609	Transcriptional regulator
DYE50_RS00790	COG4209	transmembrane transport
DYE50_RS00795	COG0395	ABC-type sugar transport system, permease component
DYE50_RS00800	COG1653	transport
DYE50_RS00810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYE50_RS00835	COG1609	Transcriptional regulator
DYE50_RS00855	COG4209	transmembrane transport
DYE50_RS00860	COG0395	ABC-type sugar transport system, permease component
DYE50_RS00875	COG0442	prolyl-tRNA aminoacylation
DYE50_RS00895	COG1028	Short-chain dehydrogenase reductase Sdr
DYE50_RS00920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYE50_RS00940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DYE50_RS00940	COG3116	cell division
DYE50_RS00945	COG0084	hydrolase, TatD family'
DYE50_RS00950	COG0739	heme binding
DYE50_RS00965	COG1774	PSP1 C-terminal conserved region
DYE50_RS00980	COG5001	Diguanylate cyclase
DYE50_RS00980	COG4251	negative regulation of phosphorylation
DYE50_RS00980	COG3706	GGDEF domain
DYE50_RS00980	COG2203	Gaf domain
DYE50_RS01035	COG1410	methionine synthase
DYE50_RS01035	COG0646	methionine synthase
DYE50_RS01040	COG0574	Belongs to the PEP-utilizing enzyme family
DYE50_RS01040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DYE50_RS01045	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DYE50_RS01060	COG1846	Transcriptional regulator
DYE50_RS01075	COG0386	Belongs to the glutathione peroxidase family
DYE50_RS01085	COG0563	adenylate kinase activity
DYE50_RS01090	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DYE50_RS01105	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DYE50_RS01110	COG1469	GTP cyclohydrolase I activity
DYE50_RS01125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DYE50_RS01130	COG1181	Belongs to the D-alanine--D-alanine ligase family
DYE50_RS01140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DYE50_RS01195	COG1522	sequence-specific DNA binding
DYE50_RS01200	COG0436	Aminotransferase
DYE50_RS01475	COG0602	queuosine metabolic process
DYE50_RS01480	COG1328	CTP reductase activity
DYE50_RS01480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DYE50_RS01485	COG2986	histidine ammonia-lyase
DYE50_RS01500	COG1115	amino acid carrier protein
DYE50_RS01505	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DYE50_RS01515	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DYE50_RS01525	COG1283	sodium-dependent phosphate transmembrane transporter activity
DYE50_RS01540	COG2252	PERMEase
DYE50_RS01545	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DYE50_RS01555	COG2816	NAD+ diphosphatase activity
DYE50_RS01585	COG1401	restriction endodeoxyribonuclease activity
DYE50_RS01610	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DYE50_RS01615	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DYE50_RS01655	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DYE50_RS01900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DYE50_RS01930	COG0674	pyruvate-flavodoxin oxidoreductase activity
DYE50_RS01930	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DYE50_RS01930	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DYE50_RS01930	COG1013	pyruvate-flavodoxin oxidoreductase activity
DYE50_RS01940	COG1396	sequence-specific DNA binding
DYE50_RS01970	COG1106	Psort location Cytoplasmic, score
DYE50_RS02010	COG0588	phosphoglycerate mutase activity
DYE50_RS02015	COG1047	Peptidyl-prolyl cis-trans
DYE50_RS02025	COG0494	nUDIX hydrolase
DYE50_RS02060	COG0501	Belongs to the peptidase M48B family
DYE50_RS02090	COG5001	Diguanylate cyclase
DYE50_RS02090	COG3300	MHYT domain
DYE50_RS02095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYE50_RS02110	COG1032	radical SAM domain protein
DYE50_RS02125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYE50_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
DYE50_RS02140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYE50_RS02150	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DYE50_RS02155	COG0167	dihydroorotate dehydrogenase activity
DYE50_RS02175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DYE50_RS02180	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DYE50_RS02190	COG0824	Thioesterase
DYE50_RS02210	COG0426	domain, Protein
DYE50_RS02220	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DYE50_RS02230	COG0747	negative chemotaxis
DYE50_RS02240	COG3437	response regulator, receiver
DYE50_RS02250	COG0745	RESPONSE REGULATOR receiver
DYE50_RS02255	COG2205	protein histidine kinase activity
DYE50_RS02270	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DYE50_RS02275	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DYE50_RS02280	COG0455	bacterial-type flagellum organization
DYE50_RS02285	COG0793	Belongs to the peptidase S41A family
DYE50_RS02305	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DYE50_RS02325	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DYE50_RS02335	COG2195	Cleaves the N-terminal amino acid of tripeptides
DYE50_RS02340	COG0475	glutathione-regulated potassium exporter activity
DYE50_RS02345	COG3842	ATPase activity
DYE50_RS02365	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DYE50_RS02370	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DYE50_RS02375	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DYE50_RS02385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DYE50_RS02385	COG0512	Glutamine amidotransferase of anthranilate synthase
DYE50_RS02390	COG0366	Alpha amylase catalytic
DYE50_RS02395	COG0134	indole-3-glycerol-phosphate synthase activity
DYE50_RS02400	COG0133	tryptophan synthase activity
DYE50_RS02405	COG0159	tryptophan synthase activity
DYE50_RS02415	COG0840	transmembrane signaling receptor activity
DYE50_RS02420	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DYE50_RS02425	COG1045	serine acetyltransferase
DYE50_RS02435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DYE50_RS02445	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DYE50_RS02450	COG0250	Participates in transcription elongation, termination and antitermination
DYE50_RS02455	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DYE50_RS02460	COG0081	regulation of translation
DYE50_RS02465	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DYE50_RS02475	COG0085	RNA polymerase activity
DYE50_RS02485	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DYE50_RS02490	COG0049	tRNA binding
DYE50_RS02495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DYE50_RS02500	COG0051	transcription antitermination factor activity, RNA binding
DYE50_RS02505	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DYE50_RS02510	COG0088	Forms part of the polypeptide exit tunnel
DYE50_RS02515	COG0089	rRNA binding
DYE50_RS02520	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DYE50_RS02525	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DYE50_RS02530	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DYE50_RS02535	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DYE50_RS02545	COG0255	Belongs to the universal ribosomal protein uL29 family
DYE50_RS02550	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DYE50_RS02555	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DYE50_RS02560	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DYE50_RS02565	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DYE50_RS02575	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DYE50_RS02580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DYE50_RS02585	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DYE50_RS02590	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DYE50_RS02600	COG0200	Binds to the 23S rRNA
DYE50_RS02610	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DYE50_RS02620	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DYE50_RS02625	COG0202	RNA polymerase activity
DYE50_RS02630	COG0203	ribosomal protein L17
DYE50_RS02695	COG2801	Transposase and inactivated derivatives
DYE50_RS02795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DYE50_RS02805	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DYE50_RS02805	COG2199	diguanylate cyclase activity
DYE50_RS02810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DYE50_RS02815	COG2755	lipolytic protein G-D-S-L family
DYE50_RS02825	COG2839	Protein conserved in bacteria
DYE50_RS02835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYE50_RS02845	COG3842	ATPase activity
DYE50_RS02850	COG4120	Belongs to the binding-protein-dependent transport system permease family
DYE50_RS02855	COG2770	Histidine kinase
DYE50_RS02855	COG2208	phosphoserine phosphatase activity
DYE50_RS02880	COG2208	phosphoserine phosphatase activity
DYE50_RS02880	COG2770	Histidine kinase
DYE50_RS02890	COG1366	Belongs to the anti-sigma-factor antagonist family
DYE50_RS02900	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DYE50_RS02905	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
DYE50_RS02910	COG0733	neurotransmitter:sodium symporter activity
DYE50_RS02960	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DYE50_RS02965	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DYE50_RS02975	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DYE50_RS02980	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DYE50_RS03000	COG2197	response regulator
DYE50_RS03020	COG0745	RESPONSE REGULATOR receiver
DYE50_RS03025	COG2205	protein histidine kinase activity
DYE50_RS03025	COG4999	Histidine kinase
DYE50_RS03025	COG3437	response regulator, receiver
DYE50_RS03025	COG3850	Histidine kinase
DYE50_RS03035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DYE50_RS03040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DYE50_RS03045	COG0484	heat shock protein binding
DYE50_RS03085	COG0714	Associated with various cellular activities
DYE50_RS03115	COG0534	Mate efflux family protein
DYE50_RS03120	COG0012	GTP binding
DYE50_RS03130	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DYE50_RS03150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYE50_RS03150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DYE50_RS03150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DYE50_RS03180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DYE50_RS03185	COG1242	4 iron, 4 sulfur cluster binding
DYE50_RS03195	COG0653	protein targeting
DYE50_RS03210	COG0564	pseudouridine synthase activity
DYE50_RS03225	COG3300	MHYT domain
DYE50_RS03225	COG5001	Diguanylate cyclase
DYE50_RS03230	COG1086	Polysaccharide biosynthesis protein
DYE50_RS03235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DYE50_RS03255	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DYE50_RS03265	COG2255	four-way junction helicase activity
DYE50_RS03270	COG0632	four-way junction helicase activity
DYE50_RS03310	COG0534	Mate efflux family protein
DYE50_RS03335	COG3330	Domain of unknown function (DUF4912)
DYE50_RS03370	COG2001	Belongs to the MraZ family
DYE50_RS03375	COG0275	rRNA processing
DYE50_RS03385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DYE50_RS03390	COG0772	Belongs to the SEDS family
DYE50_RS03395	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DYE50_RS03410	COG4974	Belongs to the 'phage' integrase family
DYE50_RS03425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DYE50_RS03425	COG0551	DNA topoisomerase type I activity
DYE50_RS03430	COG4974	Belongs to the 'phage' integrase family
DYE50_RS03435	COG0840	transmembrane signaling receptor activity
DYE50_RS03440	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DYE50_RS03445	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DYE50_RS03455	COG3706	GGDEF domain
DYE50_RS03475	COG3706	GGDEF domain
DYE50_RS03480	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DYE50_RS03490	COG0028	Belongs to the TPP enzyme family
DYE50_RS03495	COG1472	Belongs to the glycosyl hydrolase 3 family
DYE50_RS03500	COG3876	Protein conserved in bacteria
DYE50_RS03515	COG0191	fructose-bisphosphate aldolase activity
DYE50_RS03530	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYE50_RS03550	COG0779	Required for maturation of 30S ribosomal subunits
DYE50_RS03560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DYE50_RS03565	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DYE50_RS03575	COG0367	asparagine synthase
DYE50_RS03580	COG0504	CTP synthase activity
DYE50_RS03600	COG0534	Mate efflux family protein
DYE50_RS03625	COG0493	'glutamate synthase
DYE50_RS03630	COG0067	glutamate synthase
DYE50_RS03630	COG0070	glutamate synthase
DYE50_RS03630	COG0069	glutamate synthase activity
DYE50_RS03665	COG0004	ammonium transporteR
DYE50_RS03670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DYE50_RS03675	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DYE50_RS03680	COG1185	polyribonucleotide nucleotidyltransferase activity
DYE50_RS03685	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DYE50_RS03700	COG1609	Transcriptional regulator
DYE50_RS03710	COG1175	transmembrane transport
DYE50_RS03715	COG3833	ABC-type maltose transport systems, permease component
DYE50_RS03725	COG0756	dUTP diphosphatase activity
DYE50_RS03740	COG1028	Short-chain dehydrogenase reductase Sdr
DYE50_RS03745	COG0343	queuine tRNA-ribosyltransferase activity
DYE50_RS03765	COG2770	Histidine kinase
DYE50_RS03765	COG2208	phosphoserine phosphatase activity
DYE50_RS03825	COG1397	ADP-ribosylglycohydrolase
DYE50_RS03860	COG2089	acid synthase
DYE50_RS03875	COG0217	transcriptional regulatory protein
DYE50_RS03905	COG1362	aminopeptidase activity
DYE50_RS03910	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DYE50_RS03915	COG0740	serine-type endopeptidase activity
DYE50_RS03920	COG0544	peptidyl-prolyl cis-trans isomerase activity
DYE50_RS03970	COG2199	diguanylate cyclase activity
DYE50_RS04000	COG1132	(ABC) transporter
DYE50_RS04000	COG2375	cellular response to nickel ion
DYE50_RS04025	COG1309	transcriptional regulator
DYE50_RS04035	COG2217	Heavy metal translocating P-type atpase
DYE50_RS04045	COG0148	phosphopyruvate hydratase activity
DYE50_RS04060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DYE50_RS04065	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DYE50_RS04070	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DYE50_RS04075	COG1214	PFAM Peptidase M22, glycoprotease
DYE50_RS04080	COG0802	atpase or kinase
DYE50_RS04120	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DYE50_RS04145	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DYE50_RS04155	COG1473	amidohydrolase
DYE50_RS04160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DYE50_RS04165	COG2011	ABC-type metal ion transport system permease component
DYE50_RS04175	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DYE50_RS04200	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DYE50_RS04205	COG1464	Belongs to the NlpA lipoprotein family
DYE50_RS04210	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DYE50_RS04215	COG1464	Belongs to the NlpA lipoprotein family
DYE50_RS04220	COG0277	FAD linked oxidase domain protein
DYE50_RS04225	COG0436	Aminotransferase
DYE50_RS04240	COG0765	amino acid transport
DYE50_RS04245	COG0765	amino acid transport
DYE50_RS04260	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DYE50_RS04270	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DYE50_RS04285	COG1268	BioY protein
DYE50_RS04290	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DYE50_RS04295	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DYE50_RS04300	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DYE50_RS04325	COG0419	ATPase involved in DNA repair
DYE50_RS04330	COG1301	dicarboxylic acid transport
DYE50_RS04345	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DYE50_RS04355	COG0739	heme binding
DYE50_RS04365	COG1716	ATPase activity
DYE50_RS04365	COG1131	(ABC) transporter
DYE50_RS04365	COG0842	Transport permease protein
DYE50_RS04385	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DYE50_RS04390	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DYE50_RS04395	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DYE50_RS04405	COG0084	hydrolase, TatD family'
DYE50_RS04410	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DYE50_RS04420	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DYE50_RS04420	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DYE50_RS04430	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DYE50_RS04440	COG1104	cysteine desulfurase activity
DYE50_RS04445	COG0731	radical SAM domain protein
DYE50_RS04465	COG0860	N-Acetylmuramoyl-L-alanine amidase
DYE50_RS04485	COG1199	ATP-dependent helicase activity
DYE50_RS04500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DYE50_RS04515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DYE50_RS04530	COG3852	Histidine kinase
DYE50_RS04535	COG2204	response regulator
DYE50_RS04545	COG0268	Binds directly to 16S ribosomal RNA
DYE50_RS04555	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DYE50_RS04565	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DYE50_RS04575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DYE50_RS04595	COG0438	transferase activity, transferring glycosyl groups
DYE50_RS04610	COG0028	Belongs to the TPP enzyme family
DYE50_RS04610	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
DYE50_RS04625	COG0706	membrane insertase activity
DYE50_RS04630	COG0706	membrane insertase activity
DYE50_RS04635	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DYE50_RS04650	COG0706	membrane insertase activity
DYE50_RS04655	COG0706	membrane insertase activity
DYE50_RS04725	COG0706	membrane insertase activity
DYE50_RS04735	COG1216	Glycosyl transferase, family 2
DYE50_RS04775	COG1136	(ABC) transporter
DYE50_RS04795	COG1091	dTDP-4-dehydrorhamnose reductase activity
DYE50_RS04810	COG0658	competence protein
DYE50_RS04810	COG2333	competence protein COMEC
DYE50_RS04815	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DYE50_RS04830	COG0564	pseudouridine synthase activity
DYE50_RS04840	COG0436	Aminotransferase
DYE50_RS04845	COG0297	glycogen (starch) synthase activity
DYE50_RS04850	COG0360	Binds together with S18 to 16S ribosomal RNA
DYE50_RS04855	COG0629	single-stranded DNA binding
DYE50_RS04860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DYE50_RS04865	COG0359	binds to the 23S rRNA
DYE50_RS04870	COG0305	Participates in initiation and elongation during chromosome replication
DYE50_RS04885	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DYE50_RS04895	COG0617	tRNA 3'-terminal CCA addition
DYE50_RS04900	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DYE50_RS04910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYE50_RS04910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYE50_RS04920	COG0735	belongs to the Fur family
DYE50_RS04925	COG1592	Rubrerythrin
DYE50_RS04935	COG1234	tRNA 3'-trailer cleavage
DYE50_RS04945	COG3177	Filamentation induced by cAMP protein fic
DYE50_RS04955	COG0732	type I restriction modification DNA specificity domain
DYE50_RS04955	COG0732	type I restriction modification DNA specificity domain
DYE50_RS04985	COG4555	ABC transporter
DYE50_RS05005	COG0066	3-isopropylmalate dehydratase activity
DYE50_RS05010	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DYE50_RS05015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DYE50_RS05055	COG0750	zinc metalloprotease
DYE50_RS05060	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DYE50_RS05065	COG0575	Belongs to the CDS family
DYE50_RS05070	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DYE50_RS05075	COG0233	cytoplasmic translational termination
DYE50_RS05080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DYE50_RS05085	COG0052	Belongs to the universal ribosomal protein uS2 family
DYE50_RS05090	COG0424	maF-like protein
DYE50_RS05095	COG1413	lyase activity
DYE50_RS05105	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DYE50_RS05110	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DYE50_RS05120	COG0571	ribonuclease III activity
DYE50_RS05125	COG0254	rRNA binding
DYE50_RS05140	COG0513	Belongs to the DEAD box helicase family
DYE50_RS05145	COG0488	(ABC) transporter
DYE50_RS05150	COG2198	Histidine kinase
DYE50_RS05150	COG2205	protein histidine kinase activity
DYE50_RS05150	COG0784	Response regulator, receiver
DYE50_RS05160	COG2801	Transposase and inactivated derivatives
DYE50_RS05175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DYE50_RS05220	COG1690	Belongs to the RtcB family
DYE50_RS05240	COG3541	Predicted nucleotidyltransferase
DYE50_RS05270	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYE50_RS05365	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DYE50_RS05405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DYE50_RS05410	COG3386	PFAM SMP-30 Gluconolaconase
DYE50_RS05420	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DYE50_RS05440	COG3191	aminopeptidase activity
DYE50_RS05445	COG1937	Protein conserved in bacteria
DYE50_RS05470	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DYE50_RS05475	COG3177	Filamentation induced by cAMP protein fic
DYE50_RS05500	COG2770	Histidine kinase
DYE50_RS05500	COG2208	phosphoserine phosphatase activity
DYE50_RS05510	COG2315	Protein conserved in bacteria
DYE50_RS05525	COG2226	methyltransferase
DYE50_RS05595	COG0442	prolyl-tRNA aminoacylation
DYE50_RS05615	COG0454	-acetyltransferase
DYE50_RS05630	COG0251	oxidation-reduction process
DYE50_RS05655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DYE50_RS05680	COG5001	Diguanylate cyclase
DYE50_RS05680	COG3300	MHYT domain
DYE50_RS05690	COG0784	Response regulator, receiver
DYE50_RS05690	COG2205	protein histidine kinase activity
DYE50_RS05720	COG0840	transmembrane signaling receptor activity
DYE50_RS05740	COG0596	Alpha beta hydrolase
DYE50_RS05760	COG1105	Belongs to the carbohydrate kinase PfkB family
DYE50_RS05775	COG1683	Conserved Protein
DYE50_RS05835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYE50_RS05870	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DYE50_RS05875	COG0259	pyridoxamine-phosphate oxidase activity
DYE50_RS05880	COG2207	Transcriptional regulator
DYE50_RS05900	COG2378	regulation of single-species biofilm formation
DYE50_RS05905	COG0693	protein deglycase activity
DYE50_RS05930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DYE50_RS05975	COG0456	acetyltransferase
DYE50_RS05995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYE50_RS06005	COG0789	Transcriptional regulator
DYE50_RS06005	COG4978	Transcriptional regulator
DYE50_RS06020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DYE50_RS06045	COG0534	Mate efflux family protein
DYE50_RS06080	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DYE50_RS06085	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DYE50_RS06115	COG0110	maltose O-acetyltransferase activity
DYE50_RS06125	COG0519	Catalyzes the synthesis of GMP from XMP
DYE50_RS06130	COG2746	aminoglycoside 3-N-acetyltransferase activity
DYE50_RS06155	COG1192	Involved in chromosome partitioning
DYE50_RS06165	COG1794	racemase activity, acting on amino acids and derivatives
DYE50_RS06210	COG1687	branched-chain amino acid
DYE50_RS06215	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DYE50_RS06220	COG0561	phosphatase activity
DYE50_RS06230	COG1011	Hydrolase
DYE50_RS06300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DYE50_RS06310	COG1181	Belongs to the D-alanine--D-alanine ligase family
DYE50_RS06320	COG2244	polysaccharide biosynthetic process
DYE50_RS06355	COG1442	glycosyl transferase family 8
DYE50_RS06375	COG1482	cell wall glycoprotein biosynthetic process
DYE50_RS06410	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DYE50_RS06440	COG1397	ADP-ribosylglycohydrolase
DYE50_RS06465	COG1401	restriction endodeoxyribonuclease activity
DYE50_RS06505	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DYE50_RS06510	COG3421	Type III restriction
DYE50_RS06575	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYE50_RS06625	COG2801	Transposase and inactivated derivatives
DYE50_RS06635	COG0772	Belongs to the SEDS family
DYE50_RS06640	COG0768	penicillin binding
DYE50_RS06655	COG1077	Cell shape determining protein MreB Mrl
DYE50_RS06675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DYE50_RS06680	COG0358	DNA primase activity
DYE50_RS06740	COG1102	Psort location Cytoplasmic, score
DYE50_RS06745	COG1561	YicC-like family, N-terminal region
DYE50_RS06750	COG0180	Tryptophanyl-tRNA synthetase
DYE50_RS06755	COG0590	tRNA wobble adenosine to inosine editing
DYE50_RS06760	COG0285	dihydrofolate synthase activity
DYE50_RS06765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DYE50_RS06775	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DYE50_RS06785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYE50_RS06820	COG1269	ATP hydrolysis coupled proton transport
DYE50_RS06825	COG1394	ATPase activity, coupled to movement of substances
DYE50_RS06830	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DYE50_RS06835	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DYE50_RS06845	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
DYE50_RS06905	COG4656	Part of a membrane complex involved in electron transport
DYE50_RS06945	COG0028	Belongs to the TPP enzyme family
DYE50_RS06960	COG0681	Belongs to the peptidase S26 family
DYE50_RS06975	COG2116	formate transmembrane transporter activity
DYE50_RS06980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DYE50_RS07030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DYE50_RS07035	COG1450	Type ii and iii secretion system protein
DYE50_RS07050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DYE50_RS07060	COG1653	transport
DYE50_RS07135	COG1196	nuclear chromosome segregation
DYE50_RS07155	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DYE50_RS07165	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DYE50_RS07175	COG0733	neurotransmitter:sodium symporter activity
DYE50_RS07185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DYE50_RS07190	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DYE50_RS07210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DYE50_RS07220	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
DYE50_RS07250	COG0564	pseudouridine synthase activity
DYE50_RS07260	COG4786	Flagellar basal body rod
DYE50_RS07265	COG1716	ATPase activity
DYE50_RS07265	COG5001	Diguanylate cyclase
DYE50_RS07270	COG0124	histidyl-tRNA synthetase
DYE50_RS07290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DYE50_RS07295	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DYE50_RS07310	COG0640	Transcriptional regulator
DYE50_RS07325	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DYE50_RS07330	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DYE50_RS07335	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DYE50_RS07340	COG2373	Large extracellular alpha-helical protein
DYE50_RS07370	COG1846	Transcriptional regulator
DYE50_RS07375	COG4974	Belongs to the 'phage' integrase family
DYE50_RS07400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DYE50_RS07405	COG0542	response to heat
DYE50_RS07410	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DYE50_RS07445	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DYE50_RS07460	COG3869	Catalyzes the specific phosphorylation of arginine residues in
DYE50_RS07500	COG1136	(ABC) transporter
DYE50_RS07505	COG4591	ABC-type transport system involved in lipoprotein release permease component
DYE50_RS07515	COG0552	protein localization to endoplasmic reticulum
DYE50_RS07550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DYE50_RS07555	COG1480	7TM receptor with intracellular HD hydrolase
DYE50_RS07560	COG1702	phosphate starvation-inducible protein PhoH
DYE50_RS07575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DYE50_RS07580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DYE50_RS07585	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DYE50_RS07610	COG1191	sigma factor activity
DYE50_RS07620	COG0455	bacterial-type flagellum organization
DYE50_RS07625	COG1419	protein localization to endoplasmic reticulum
DYE50_RS07630	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DYE50_RS07635	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DYE50_RS07640	COG1684	flagellar biosynthetic protein fliR
DYE50_RS07645	COG1987	bacterial-type flagellum assembly
DYE50_RS07650	COG1338	Plays a role in the flagellum-specific transport system
DYE50_RS07665	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYE50_RS07670	COG1580	Controls the rotational direction of flagella during chemotaxis
DYE50_RS07675	COG1360	Flagellar Motor Protein
DYE50_RS07685	COG1582	Flagellar protein (FlbD)
DYE50_RS07690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DYE50_RS07700	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DYE50_RS07710	COG0009	L-threonylcarbamoyladenylate synthase
DYE50_RS07755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DYE50_RS07760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DYE50_RS07770	COG1022	Amp-dependent synthetase and ligase
DYE50_RS07785	COG0170	dolichyl monophosphate biosynthetic process
DYE50_RS07800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DYE50_RS07805	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DYE50_RS07810	COG0105	UTP biosynthetic process
DYE50_RS07815	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DYE50_RS07825	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DYE50_RS07830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DYE50_RS07835	COG1862	Preprotein translocase
DYE50_RS07855	COG0741	lytic transglycosylase activity
DYE50_RS07855	COG1388	LysM domain
DYE50_RS07870	COG0436	Aminotransferase
DYE50_RS07875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DYE50_RS07880	COG2211	Major facilitator Superfamily
DYE50_RS07885	COG1309	transcriptional regulator
DYE50_RS07915	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DYE50_RS07965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DYE50_RS07980	COG0826	peptidase U32
DYE50_RS07990	COG0301	tRNA thio-modification
DYE50_RS08010	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DYE50_RS08015	COG1573	uracil-dna glycosylase
DYE50_RS08020	COG0101	tRNA pseudouridine synthase activity
DYE50_RS08030	COG0736	holo-[acyl-carrier-protein] synthase activity
DYE50_RS08045	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DYE50_RS08050	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DYE50_RS08065	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DYE50_RS08065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DYE50_RS08070	COG5001	Diguanylate cyclase
DYE50_RS08075	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DYE50_RS08085	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DYE50_RS08100	COG0741	lytic transglycosylase activity
DYE50_RS08100	COG0739	heme binding
DYE50_RS08100	COG1196	nuclear chromosome segregation
DYE50_RS08145	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DYE50_RS08155	COG0539	negative regulation of cytoplasmic translation
DYE50_RS08160	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DYE50_RS08170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DYE50_RS08175	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DYE50_RS08180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DYE50_RS08185	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DYE50_RS08205	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DYE50_RS08215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DYE50_RS08215	COG1747	RNA polymerase binding
DYE50_RS08240	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DYE50_RS08255	COG4120	Belongs to the binding-protein-dependent transport system permease family
DYE50_RS08265	COG2199	diguanylate cyclase activity
DYE50_RS08270	COG1475	DNA binding
DYE50_RS08275	COG1192	Involved in chromosome partitioning
DYE50_RS08285	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DYE50_RS08300	COG2801	Transposase and inactivated derivatives
DYE50_RS08330	COG0423	glycine-tRNA ligase activity
DYE50_RS08340	COG2199	diguanylate cyclase activity
DYE50_RS08340	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DYE50_RS08345	COG2604	Protein of unknown function DUF115
DYE50_RS08360	COG0739	heme binding
DYE50_RS08360	COG1196	nuclear chromosome segregation
DYE50_RS08360	COG0741	lytic transglycosylase activity
DYE50_RS08370	COG0726	polysaccharide deacetylase
DYE50_RS08375	COG2755	lipolytic protein G-D-S-L family
DYE50_RS08385	COG1686	Belongs to the peptidase S11 family
DYE50_RS08390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DYE50_RS08395	COG1028	Short-chain dehydrogenase reductase Sdr
DYE50_RS08400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYE50_RS08410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYE50_RS08415	COG0765	amino acid transport
DYE50_RS08420	COG1126	abc transporter atp-binding protein
DYE50_RS08455	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
DYE50_RS08460	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
DYE50_RS08470	COG0826	peptidase U32
DYE50_RS08525	COG0523	cobalamin synthesis protein
DYE50_RS08535	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DYE50_RS08555	COG0697	spore germination
DYE50_RS08560	COG0564	pseudouridine synthase activity
DYE50_RS08570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYE50_RS08575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DYE50_RS08580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DYE50_RS08585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DYE50_RS08595	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DYE50_RS08600	COG0737	Belongs to the 5'-nucleotidase family
DYE50_RS08605	COG0626	cystathionine gamma-synthase activity
DYE50_RS08610	COG1959	2 iron, 2 sulfur cluster binding
DYE50_RS08620	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DYE50_RS08625	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DYE50_RS08635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DYE50_RS08655	COG1187	pseudouridine synthase activity
DYE50_RS08660	COG0372	Belongs to the citrate synthase family
DYE50_RS08670	COG2502	aspartate--ammonia ligase
DYE50_RS08695	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
DYE50_RS08725	COG1984	allophanate hydrolase subunit 2
DYE50_RS08730	COG4336	lyase activity
DYE50_RS08745	COG1472	Belongs to the glycosyl hydrolase 3 family
DYE50_RS08755	COG1175	transmembrane transport
DYE50_RS08760	COG3833	ABC-type maltose transport systems, permease component
DYE50_RS08780	COG0126	phosphoglycerate kinase activity
DYE50_RS08785	COG0149	triose-phosphate isomerase activity
DYE50_RS08795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYE50_RS08795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYE50_RS08795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYE50_RS08810	COG1269	ATP hydrolysis coupled proton transport
DYE50_RS08830	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
DYE50_RS08835	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DYE50_RS08840	COG1394	ATPase activity, coupled to movement of substances
DYE50_RS08845	COG0589	response to stress
DYE50_RS08850	COG1609	Transcriptional regulator
DYE50_RS08855	COG1653	transport
DYE50_RS08860	COG1175	transmembrane transport
DYE50_RS08865	COG0395	ABC-type sugar transport system, permease component
DYE50_RS08880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYE50_RS08900	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DYE50_RS08905	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DYE50_RS08915	COG2201	protein-glutamate methylesterase activity
DYE50_RS08920	COG3845	ABC transporter
DYE50_RS08935	COG1592	Rubrerythrin
DYE50_RS08940	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DYE50_RS08980	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DYE50_RS09000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DYE50_RS09010	COG5001	Diguanylate cyclase
DYE50_RS09015	COG0784	Response regulator, receiver
DYE50_RS09015	COG2205	protein histidine kinase activity
DYE50_RS09015	COG5002	protein histidine kinase activity
DYE50_RS09040	COG3842	ATPase activity
DYE50_RS09045	COG0557	exoribonuclease II activity
DYE50_RS09050	COG0484	heat shock protein binding
DYE50_RS09055	COG0024	Methionine aminopeptidase
DYE50_RS09065	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DYE50_RS09075	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DYE50_RS09080	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DYE50_RS09100	COG0799	negative regulation of ribosome biogenesis
DYE50_RS09110	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DYE50_RS09125	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DYE50_RS09130	COG0037	tRNA processing
DYE50_RS09135	COG0457	Tetratricopeptide repeat
DYE50_RS09140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYE50_RS09145	COG0481	GTPase activity
DYE50_RS09150	COG2604	Protein of unknown function DUF115
DYE50_RS09165	COG1917	Cupin 2, conserved barrel domain protein
DYE50_RS09165	COG4977	sequence-specific DNA binding
DYE50_RS09170	COG0366	Alpha amylase catalytic
DYE50_RS09175	COG3833	ABC-type maltose transport systems, permease component
DYE50_RS09180	COG1175	transmembrane transport
DYE50_RS09185	COG2182	Extracellular solute-binding protein
DYE50_RS09200	COG0366	Alpha amylase catalytic
DYE50_RS09200	COG1874	Beta-galactosidase
DYE50_RS09205	COG1523	belongs to the glycosyl hydrolase 13 family
DYE50_RS09210	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYE50_RS09225	COG0473	3-isopropylmalate dehydrogenase activity
DYE50_RS09240	COG1175	transmembrane transport
DYE50_RS09245	COG0395	ABC-type sugar transport system, permease component
DYE50_RS09250	COG3507	Belongs to the glycosyl hydrolase 43 family
DYE50_RS09255	COG1609	Transcriptional regulator
DYE50_RS09260	COG1070	Carbohydrate kinase
DYE50_RS09280	COG0659	secondary active sulfate transmembrane transporter activity
DYE50_RS09285	COG1234	tRNA 3'-trailer cleavage
DYE50_RS09290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DYE50_RS09315	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DYE50_RS09320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DYE50_RS09350	COG0017	Asparaginyl-tRNA synthetase
DYE50_RS09355	COG2358	TRAP transporter, solute receptor (TAXI family
DYE50_RS09370	COG0142	geranyltranstransferase activity
DYE50_RS09395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYE50_RS09405	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DYE50_RS09415	COG1640	4-alpha-glucanotransferase
DYE50_RS09420	COG2059	Chromate
DYE50_RS09430	COG0813	purine-nucleoside phosphorylase activity
DYE50_RS09440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYE50_RS09445	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
DYE50_RS09450	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DYE50_RS09455	COG0156	8-amino-7-oxononanoate synthase activity
DYE50_RS09460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
DYE50_RS09475	COG1482	cell wall glycoprotein biosynthetic process
DYE50_RS09485	COG5001	Diguanylate cyclase
DYE50_RS09485	COG1716	ATPase activity
DYE50_RS09500	COG0588	phosphoglycerate mutase activity
DYE50_RS09585	COG0747	negative chemotaxis
DYE50_RS09590	COG0204	Acyl-transferase
DYE50_RS09595	COG0601	transmembrane transport
DYE50_RS09600	COG0444	Belongs to the ABC transporter superfamily
DYE50_RS09605	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DYE50_RS09640	COG2201	protein-glutamate methylesterase activity
DYE50_RS09650	COG0643	Histidine kinase
DYE50_RS09650	COG0784	Response regulator, receiver
DYE50_RS09650	COG2198	Histidine kinase
DYE50_RS09660	COG4608	Belongs to the ABC transporter superfamily
DYE50_RS09670	COG1757	Na H antiporter
DYE50_RS09680	COG0564	pseudouridine synthase activity
DYE50_RS09710	COG1366	Belongs to the anti-sigma-factor antagonist family
DYE50_RS09725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYE50_RS09740	COG1837	Belongs to the UPF0109 family
DYE50_RS09745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DYE50_RS09750	COG0336	Belongs to the RNA methyltransferase TrmD family
DYE50_RS09755	COG0335	large ribosomal subunit rRNA binding
DYE50_RS09765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DYE50_RS09775	COG0792	nuclease activity
DYE50_RS09800	COG0084	hydrolase, TatD family'
DYE50_RS09805	COG0166	Belongs to the GPI family
DYE50_RS09810	COG0822	iron-sulfur transferase activity
DYE50_RS09815	COG5002	protein histidine kinase activity
DYE50_RS09820	COG0745	RESPONSE REGULATOR receiver
DYE50_RS09835	COG0396	ATPase activity
DYE50_RS09840	COG0719	Fe-S assembly protein
DYE50_RS09845	COG0719	Fe-S assembly protein
DYE50_RS09855	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DYE50_RS09865	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DYE50_RS09875	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYE50_RS09885	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DYE50_RS09895	COG0493	'glutamate synthase
DYE50_RS09900	COG0835	chemotaxis
DYE50_RS09910	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DYE50_RS09915	COG0497	DNA recombination
DYE50_RS09930	COG3942	CHAP domain
DYE50_RS09930	COG1388	LysM domain
DYE50_RS09945	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DYE50_RS09950	COG3437	response regulator, receiver
DYE50_RS09950	COG2770	Histidine kinase
DYE50_RS09955	COG1671	Belongs to the UPF0178 family
DYE50_RS09960	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DYE50_RS09990	COG1472	Belongs to the glycosyl hydrolase 3 family
DYE50_RS10000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DYE50_RS10015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DYE50_RS10045	COG1193	negative regulation of DNA recombination
DYE50_RS10050	COG0572	uridine kinase
DYE50_RS10055	COG1438	arginine binding
DYE50_RS10065	COG1157	protein secretion by the type III secretion system
DYE50_RS10070	COG1317	bacterial-type flagellum organization
DYE50_RS10075	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DYE50_RS10080	COG1766	The M ring may be actively involved in energy transduction
DYE50_RS10085	COG1677	Flagellar hook-basal body complex protein FliE
DYE50_RS10100	COG1126	abc transporter atp-binding protein
DYE50_RS10105	COG0765	amino acid transport
DYE50_RS10110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYE50_RS10120	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DYE50_RS10150	COG0542	response to heat
DYE50_RS10155	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DYE50_RS10160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DYE50_RS10165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DYE50_RS10170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYE50_RS10175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYE50_RS10185	COG0018	arginyl-trna synthetase
DYE50_RS10190	COG0622	Phosphoesterase
DYE50_RS10200	COG2357	RelA SpoT domain protein
DYE50_RS10205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DYE50_RS10210	COG0720	synthase
DYE50_RS10215	COG2201	protein-glutamate methylesterase activity
DYE50_RS10225	COG0835	chemotaxis
DYE50_RS10230	COG0643	Histidine kinase
DYE50_RS10230	COG2198	Histidine kinase
DYE50_RS10235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DYE50_RS10245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DYE50_RS10250	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DYE50_RS10255	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DYE50_RS10275	COG1477	protein flavinylation
DYE50_RS10285	COG1172	Belongs to the binding-protein-dependent transport system permease family
DYE50_RS10295	COG4213	ABC transporter substrate-binding protein
DYE50_RS10300	COG4213	ABC transporter substrate-binding protein
DYE50_RS10305	COG2207	Transcriptional regulator
DYE50_RS10310	COG2972	Histidine kinase
DYE50_RS10320	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DYE50_RS10340	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DYE50_RS10350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DYE50_RS10380	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DYE50_RS10385	COG0154	amidase activity
DYE50_RS10425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DYE50_RS10440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DYE50_RS10445	COG1516	flagellar protein fliS
DYE50_RS10485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DYE50_RS10500	COG1595	DNA-templated transcription, initiation
DYE50_RS10510	COG0739	heme binding
DYE50_RS10510	COG0741	lytic transglycosylase activity
DYE50_RS10510	COG1196	nuclear chromosome segregation
DYE50_RS10515	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DYE50_RS10520	COG1418	mRNA catabolic process
DYE50_RS10525	COG1137	ATPase activity
DYE50_RS10545	COG2201	protein-glutamate methylesterase activity
DYE50_RS10550	COG0523	cobalamin synthesis protein
DYE50_RS10570	COG1131	(ABC) transporter
DYE50_RS10600	COG1395	domain, Protein
DYE50_RS10625	COG2199	diguanylate cyclase activity
DYE50_RS10640	COG1739	Uncharacterized protein family UPF0029
DYE50_RS10655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DYE50_RS10670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DYE50_RS10675	COG1597	lipid kinase activity
DYE50_RS10690	COG1876	peptidase activity
DYE50_RS10710	COG0724	RNA recognition motif
DYE50_RS10715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DYE50_RS10720	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DYE50_RS10740	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DYE50_RS10775	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DYE50_RS10780	COG0215	cysteine-tRNA ligase activity
DYE50_RS10795	COG1305	Transglutaminase-like
DYE50_RS10800	COG0528	UMP kinase activity
DYE50_RS10815	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYE50_RS10815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYE50_RS10815	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYE50_RS10830	COG1640	4-alpha-glucanotransferase
DYE50_RS10840	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DYE50_RS10850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYE50_RS10855	COG1653	transport
DYE50_RS10860	COG2873	o-acetylhomoserine
DYE50_RS10865	COG2189	Belongs to the N(4) N(6)-methyltransferase family
DYE50_RS10875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DYE50_RS10890	COG3300	MHYT domain
DYE50_RS10890	COG5001	Diguanylate cyclase
DYE50_RS10905	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DYE50_RS10915	COG0138	bifunctional purine biosynthesis protein purh
DYE50_RS10930	COG4555	ABC transporter
DYE50_RS10935	COG2207	Transcriptional regulator
DYE50_RS10935	COG1917	Cupin 2, conserved barrel domain protein
DYE50_RS10945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DYE50_RS10960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DYE50_RS10965	COG1879	ABC-type sugar transport system periplasmic component
DYE50_RS10980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DYE50_RS10990	COG1136	(ABC) transporter
DYE50_RS11020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DYE50_RS11040	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DYE50_RS11055	COG1116	anion transmembrane transporter activity
DYE50_RS11085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DYE50_RS11100	COG1126	abc transporter atp-binding protein
DYE50_RS11105	COG0765	amino acid transport
DYE50_RS11110	COG0765	amino acid transport
DYE50_RS11115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYE50_RS11120	COG0583	DNA-binding transcription factor activity
DYE50_RS11125	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
DYE50_RS11145	COG0386	Belongs to the glutathione peroxidase family
DYE50_RS11155	COG1979	alcohol dehydrogenase
DYE50_RS11160	COG2816	NAD+ diphosphatase activity
DYE50_RS11195	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DYE50_RS11220	COG0811	peptide transport
DYE50_RS11250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DYE50_RS11255	COG0800	Aldolase
DYE50_RS11260	COG1472	Belongs to the glycosyl hydrolase 3 family
DYE50_RS11290	COG0495	leucyl-tRNA aminoacylation
DYE50_RS11320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYE50_RS11340	COG2770	Histidine kinase
DYE50_RS11340	COG2208	phosphoserine phosphatase activity
DYE50_RS11365	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DYE50_RS11410	COG0556	nucleotide-excision repair
DYE50_RS11455	COG3250	beta-galactosidase activity
DYE50_RS11465	COG0460	homoserine dehydrogenase
DYE50_RS11465	COG0527	aspartate kinase activity
DYE50_RS11495	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DYE50_RS11500	COG3706	GGDEF domain
DYE50_RS11520	COG3706	GGDEF domain
DYE50_RS11530	COG1523	belongs to the glycosyl hydrolase 13 family
DYE50_RS11535	COG0366	Alpha amylase catalytic
DYE50_RS11545	COG0366	Alpha amylase catalytic
DYE50_RS11545	COG1874	Beta-galactosidase
DYE50_RS11555	COG0525	valine-tRNA ligase activity
DYE50_RS11565	COG5001	Diguanylate cyclase
DYE50_RS11565	COG3300	MHYT domain
DYE50_RS11570	COG0137	argininosuccinate synthase activity
DYE50_RS11595	COG0745	RESPONSE REGULATOR receiver
DYE50_RS11605	COG1660	Displays ATPase and GTPase activities
DYE50_RS11610	COG1454	alcohol dehydrogenase
DYE50_RS11610	COG1012	belongs to the aldehyde dehydrogenase family
DYE50_RS11625	COG0484	heat shock protein binding
DYE50_RS11630	COG0443	Heat shock 70 kDa protein
DYE50_RS11635	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DYE50_RS11640	COG0440	acetolactate synthase activity
DYE50_RS11655	COG1183	phosphatidylcholine synthase activity
DYE50_RS11660	COG0688	phosphatidylethanolamine metabolic process
DYE50_RS11680	COG4584	PFAM Integrase catalytic
DYE50_RS11710	COG2003	Belongs to the UPF0758 family
DYE50_RS11735	COG4962	Type ii secretion system protein e
DYE50_RS11755	COG3451	type IV secretory pathway VirB4
DYE50_RS11830	COG0582	viral genome integration into host DNA
DYE50_RS11850	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
DYE50_RS11870	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DYE50_RS11870	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DYE50_RS11880	COG1733	regulation of RNA biosynthetic process
DYE50_RS11910	COG1132	(ABC) transporter
DYE50_RS11920	COG1309	transcriptional regulator
DYE50_RS11930	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYE50_RS11940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DYE50_RS11945	COG0129	dihydroxy-acid dehydratase activity
DYE50_RS11950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYE50_RS11985	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DYE50_RS12000	COG3759	membrane
DYE50_RS12010	COG1737	Transcriptional regulator
DYE50_RS12020	COG1177	transmembrane transport
DYE50_RS12025	COG3842	ATPase activity
DYE50_RS12035	COG2207	Transcriptional regulator
DYE50_RS12035	COG4753	response regulator
DYE50_RS12040	COG2972	Histidine kinase
DYE50_RS12045	COG0395	ABC-type sugar transport system, permease component
DYE50_RS12050	COG1175	transmembrane transport
DYE50_RS12065	COG0446	pyridine nucleotide-disulphide oxidoreductase
DYE50_RS12105	COG0803	Belongs to the bacterial solute-binding protein 9 family
DYE50_RS12105	COG3443	Belongs to the bacterial solute-binding protein 9 family
DYE50_RS12110	COG1121	(ABC) transporter
DYE50_RS12125	COG3706	GGDEF domain
DYE50_RS12140	COG1205	dead DEAH box helicase
DYE50_RS12140	COG1111	helicase
DYE50_RS12145	COG4209	transmembrane transport
DYE50_RS12150	COG0395	ABC-type sugar transport system, permease component
DYE50_RS12155	COG1653	transport
DYE50_RS12180	COG4209	transmembrane transport
DYE50_RS12185	COG0395	ABC-type sugar transport system, permease component
DYE50_RS12190	COG1653	transport
DYE50_RS12195	COG3119	arylsulfatase activity
DYE50_RS12200	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DYE50_RS12315	COG0037	tRNA processing
DYE50_RS12320	COG5505	Protein of unknown function (DUF819)
DYE50_RS12330	COG0640	Transcriptional regulator
DYE50_RS12335	COG2217	Heavy metal translocating P-type atpase
DYE50_RS12340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DYE50_RS12345	COG1418	mRNA catabolic process
DYE50_RS12380	COG0640	Transcriptional regulator
DYE50_RS12400	COG0534	Mate efflux family protein
DYE50_RS12405	COG0534	Mate efflux family protein
DYE50_RS12410	COG0534	Mate efflux family protein
DYE50_RS12415	COG0527	aspartate kinase activity
DYE50_RS12425	COG3842	ATPase activity
DYE50_RS12430	COG1854	S-ribosylhomocysteine lyase activity
DYE50_RS12435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DYE50_RS12450	COG0583	DNA-binding transcription factor activity
DYE50_RS12465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DYE50_RS12490	COG0579	oxidoreductase
DYE50_RS12495	COG0446	pyridine nucleotide-disulphide oxidoreductase
DYE50_RS12595	COG0534	Mate efflux family protein