locus-tag	class	description
QI63_RS00050	COG3956	TIGRFAM MazG family protein
QI63_RS00055	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
QI63_RS00065	COG1747	RNA polymerase binding
QI63_RS00065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
QI63_RS00075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
QI63_RS00100	COG1234	tRNA 3'-trailer cleavage
QI63_RS00110	COG4254	PFAM FecR protein
QI63_RS00120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
QI63_RS00125	COG0154	amidase activity
QI63_RS00130	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
QI63_RS00140	COG2211	Major facilitator Superfamily
QI63_RS00160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
QI63_RS00170	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
QI63_RS00190	COG0228	four-way junction DNA binding
QI63_RS00195	COG1837	Belongs to the UPF0109 family
QI63_RS00200	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
QI63_RS00205	COG0336	Belongs to the RNA methyltransferase TrmD family
QI63_RS00210	COG0335	large ribosomal subunit rRNA binding
QI63_RS00240	COG0495	leucyl-tRNA aminoacylation
QI63_RS00250	COG1773	rubredoxin
QI63_RS00265	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
QI63_RS00275	COG2358	TRAP transporter, solute receptor (TAXI family
QI63_RS00290	COG0343	queuine tRNA-ribosyltransferase activity
QI63_RS00305	COG0116	Belongs to the methyltransferase superfamily
QI63_RS00305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
QI63_RS00310	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
QI63_RS00315	COG1413	lyase activity
QI63_RS00330	COG1482	cell wall glycoprotein biosynthetic process
QI63_RS00335	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
QI63_RS00340	COG1573	uracil-dna glycosylase
QI63_RS00350	COG2971	BadF BadG BcrA BcrD
QI63_RS00370	COG1653	transport
QI63_RS00375	COG1175	transmembrane transport
QI63_RS00380	COG0395	ABC-type sugar transport system, permease component
QI63_RS00390	COG4166	transmembrane transport
QI63_RS00395	COG1620	l-lactate permease
QI63_RS00400	COG1309	transcriptional regulator
QI63_RS00410	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
QI63_RS00420	COG1653	transport
QI63_RS00450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
QI63_RS00455	COG1598	PFAM Uncharacterised protein family UPF0150
QI63_RS00470	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
QI63_RS00475	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
QI63_RS00480	COG0297	glycogen (starch) synthase activity
QI63_RS00490	COG0523	cobalamin synthesis protein
QI63_RS00495	COG1272	protein, Hemolysin III
QI63_RS00500	COG0254	rRNA binding
QI63_RS00505	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
QI63_RS00510	COG1546	Belongs to the CinA family
QI63_RS00510	COG1058	Belongs to the CinA family
QI63_RS00520	COG0815	Transfers the fatty acyl group on membrane lipoproteins
QI63_RS00525	COG0776	regulation of translation
QI63_RS00530	COG0268	Binds directly to 16S ribosomal RNA
QI63_RS00550	COG0860	N-Acetylmuramoyl-L-alanine amidase
QI63_RS00575	COG0731	radical SAM domain protein
QI63_RS00590	COG2201	protein-glutamate methylesterase activity
QI63_RS00600	COG0835	chemotaxis
QI63_RS00605	COG2198	Histidine kinase
QI63_RS00605	COG0643	Histidine kinase
QI63_RS00620	COG3118	belongs to the thioredoxin family
QI63_RS00630	COG0617	tRNA 3'-terminal CCA addition
QI63_RS00635	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
QI63_RS00655	COG2388	GCN5-related N-acetyl-transferase
QI63_RS00660	COG2885	chlorophyll binding
QI63_RS00675	COG0583	DNA-binding transcription factor activity
QI63_RS00680	COG0785	Cytochrome C biogenesis protein
QI63_RS00725	COG3328	transposase activity
QI63_RS00745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
QI63_RS00770	COG4209	transmembrane transport
QI63_RS00775	COG0395	ABC-type sugar transport system, permease component
QI63_RS00790	COG2226	methyltransferase
QI63_RS00795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
QI63_RS00810	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
QI63_RS00815	COG0815	Transfers the fatty acyl group on membrane lipoproteins
QI63_RS00820	COG1293	RNA-binding protein homologous to eukaryotic snRNP
QI63_RS00850	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
QI63_RS00860	COG0569	domain protein
QI63_RS00865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
QI63_RS00885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
QI63_RS00890	COG1067	ATP-dependent peptidase activity
QI63_RS00900	COG0456	acetyltransferase
QI63_RS00945	COG3620	sequence-specific DNA binding
QI63_RS00955	COG3142	Participates in the control of copper homeostasis
QI63_RS00980	COG2604	Protein of unknown function DUF115
QI63_RS00990	COG0405	Gamma-glutamyltransferase
QI63_RS01010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
QI63_RS01015	COG0446	pyridine nucleotide-disulphide oxidoreductase
QI63_RS01025	COG1070	Carbohydrate kinase
QI63_RS01045	COG3549	Plasmid maintenance system killer
QI63_RS01075	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
QI63_RS01075	COG0302	gtp cyclohydrolase
QI63_RS01080	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
QI63_RS01085	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
QI63_RS01115	COG2001	Belongs to the MraZ family
QI63_RS01120	COG0275	rRNA processing
QI63_RS01130	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
QI63_RS01135	COG0772	Belongs to the SEDS family
QI63_RS01140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
QI63_RS01150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
QI63_RS01160	COG2233	PERMEase
QI63_RS01175	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
QI63_RS01195	COG0187	DNA topoisomerase II activity
QI63_RS01200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
QI63_RS01235	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
QI63_RS01265	COG3579	cysteine-type endopeptidase activity
QI63_RS01270	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
QI63_RS01275	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
QI63_RS01280	COG1815	bacterial-type flagellum-dependent cell motility
QI63_RS01295	COG1766	The M ring may be actively involved in energy transduction
QI63_RS01305	COG1317	bacterial-type flagellum organization
QI63_RS01310	COG1157	protein secretion by the type III secretion system
QI63_RS01335	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
QI63_RS01340	COG0840	transmembrane signaling receptor activity
QI63_RS01345	COG0571	ribonuclease III activity
QI63_RS01350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
QI63_RS01355	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
QI63_RS01390	COG1921	L-seryl-tRNASec selenium transferase activity
QI63_RS01400	COG0840	transmembrane signaling receptor activity
QI63_RS01410	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
QI63_RS01410	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
QI63_RS01430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QI63_RS01445	COG0395	ABC-type sugar transport system, permease component
QI63_RS01450	COG1175	transmembrane transport
QI63_RS01460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
QI63_RS01465	COG0328	RNA-DNA hybrid ribonuclease activity
QI63_RS01470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
QI63_RS01475	COG0628	permease
QI63_RS01480	COG0363	glucosamine-6-phosphate deaminase activity
QI63_RS01485	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
QI63_RS01495	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
QI63_RS01500	COG0488	(ABC) transporter
QI63_RS01530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
QI63_RS01530	COG3116	cell division
QI63_RS01535	COG0084	hydrolase, TatD family'
QI63_RS01545	COG1464	Belongs to the NlpA lipoprotein family
QI63_RS01560	COG1477	protein flavinylation
QI63_RS01570	COG3588	fructose-bisphosphate aldolase
QI63_RS01595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
QI63_RS01620	COG0322	excinuclease ABC activity
QI63_RS01625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
QI63_RS01645	COG0301	tRNA thio-modification
QI63_RS01655	COG2502	aspartate--ammonia ligase
QI63_RS01680	COG0217	transcriptional regulatory protein
QI63_RS01685	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
QI63_RS01695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
QI63_RS01710	COG0049	tRNA binding
QI63_RS01725	COG0085	RNA polymerase activity
QI63_RS01730	COG0222	ribosome binding
QI63_RS01735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
QI63_RS01740	COG0081	regulation of translation
QI63_RS01745	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
QI63_RS01750	COG0250	Participates in transcription elongation, termination and antitermination
QI63_RS01755	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
QI63_RS01765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
QI63_RS01780	COG1438	arginine binding
QI63_RS01785	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
QI63_RS01800	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
QI63_RS01805	COG2801	Transposase and inactivated derivatives
QI63_RS01810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
QI63_RS01840	COG1129	ABC transporter
QI63_RS01875	COG0616	signal peptide processing
QI63_RS01880	COG4608	Belongs to the ABC transporter superfamily
QI63_RS01885	COG0444	Belongs to the ABC transporter superfamily
QI63_RS01890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QI63_RS01895	COG0601	transmembrane transport
QI63_RS01910	COG0826	peptidase U32
QI63_RS01920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
QI63_RS01985	COG1484	DNA-dependent DNA replication
QI63_RS02155	COG3451	type IV secretory pathway VirB4
QI63_RS02180	COG4962	Type ii secretion system protein e
QI63_RS02210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
QI63_RS02210	COG0551	DNA topoisomerase type I activity
QI63_RS02235	COG0739	heme binding
QI63_RS02250	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
QI63_RS02260	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
QI63_RS02265	COG2911	Protein conserved in bacteria
QI63_RS02275	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
QI63_RS02285	COG0739	heme binding
QI63_RS02300	COG1774	PSP1 C-terminal conserved region
QI63_RS02315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
QI63_RS02320	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
QI63_RS02325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
QI63_RS02340	COG0762	integral membrane protein
QI63_RS02350	COG0427	acetyl-CoA hydrolase
QI63_RS02355	COG1024	Enoyl-CoA hydratase
QI63_RS02360	COG1250	3-hydroxyacyl-CoA dehydrogenase
QI63_RS02365	COG1309	transcriptional regulator
QI63_RS02370	COG3848	Pyruvate phosphate dikinase
QI63_RS02370	COG0574	Belongs to the PEP-utilizing enzyme family
QI63_RS02375	COG0534	Mate efflux family protein
QI63_RS02385	COG2801	Transposase and inactivated derivatives
QI63_RS02405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
QI63_RS02420	COG0167	dihydroorotate dehydrogenase activity
QI63_RS02425	COG0543	2 iron, 2 sulfur cluster binding
QI63_RS02430	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
QI63_RS02435	COG0540	Belongs to the ATCase OTCase family
QI63_RS02440	COG0668	transmembrane transport
QI63_RS02455	COG1132	(ABC) transporter
QI63_RS02455	COG2375	cellular response to nickel ion
QI63_RS02470	COG1132	(ABC) transporter
QI63_RS02475	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
QI63_RS02480	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
QI63_RS02540	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
QI63_RS02545	COG1882	Formate acetyltransferase
QI63_RS02550	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
QI63_RS02555	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
QI63_RS02560	COG5001	Diguanylate cyclase
QI63_RS02560	COG4251	negative regulation of phosphorylation
QI63_RS02560	COG3706	GGDEF domain
QI63_RS02560	COG2203	Gaf domain
QI63_RS02565	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
QI63_RS02570	COG0205	6-phosphofructokinase activity
QI63_RS02575	COG0124	histidyl-tRNA synthetase
QI63_RS02590	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
QI63_RS02600	COG0840	transmembrane signaling receptor activity
QI63_RS02635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
QI63_RS02650	COG3437	response regulator, receiver
QI63_RS02650	COG2770	Histidine kinase
QI63_RS02655	COG1214	PFAM Peptidase M22, glycoprotease
QI63_RS02660	COG0802	atpase or kinase
QI63_RS02665	COG0564	pseudouridine synthase activity
QI63_RS02675	COG0220	tRNA (guanine-N7-)-methyltransferase activity
QI63_RS02690	COG0297	glycogen (starch) synthase activity
QI63_RS02725	COG1027	Aspartate ammonia-lyase
QI63_RS02730	COG0295	cytidine deaminase activity
QI63_RS02740	COG0739	heme binding
QI63_RS02770	COG0746	molybdenum cofactor guanylyltransferase activity
QI63_RS02785	COG0556	nucleotide-excision repair
QI63_RS02790	COG0709	Synthesizes selenophosphate from selenide and ATP
QI63_RS02835	COG1744	ABC transporter substrate-binding protein PnrA-like
QI63_RS02840	COG3845	ABC transporter
QI63_RS02845	COG4603	Belongs to the binding-protein-dependent transport system permease family
QI63_RS02850	COG1079	Belongs to the binding-protein-dependent transport system permease family
QI63_RS02895	COG1418	mRNA catabolic process
QI63_RS02900	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
QI63_RS02910	COG1475	DNA binding
QI63_RS02915	COG1192	Involved in chromosome partitioning
QI63_RS02920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
QI63_RS02965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
QI63_RS02975	COG1216	Glycosyl transferase, family 2
QI63_RS02975	COG1442	glycosyl transferase family 8
QI63_RS03020	COG1373	ATPase (AAA superfamily
QI63_RS03055	COG1362	aminopeptidase activity
QI63_RS03060	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
QI63_RS03105	COG1181	Belongs to the D-alanine--D-alanine ligase family
QI63_RS03110	COG1966	Carbon starvation protein
QI63_RS03115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
QI63_RS03120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
QI63_RS03130	COG1079	Belongs to the binding-protein-dependent transport system permease family
QI63_RS03140	COG3845	ABC transporter
QI63_RS03145	COG1744	ABC transporter substrate-binding protein PnrA-like
QI63_RS03155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
QI63_RS03160	COG3876	Protein conserved in bacteria
QI63_RS03170	COG2239	Acts as a magnesium transporter
QI63_RS03175	COG0170	dolichyl monophosphate biosynthetic process
QI63_RS03185	COG2252	PERMEase
QI63_RS03225	COG0733	neurotransmitter:sodium symporter activity
QI63_RS03230	COG0457	Tetratricopeptide repeat
QI63_RS03235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
QI63_RS03240	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
QI63_RS03250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
QI63_RS03255	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
QI63_RS03270	COG0058	SHG alpha-glucan phosphorylase activity
QI63_RS03280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
QI63_RS03290	COG1040	competence protein
QI63_RS03295	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
QI63_RS03300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
QI63_RS03305	COG1862	Preprotein translocase
QI63_RS03310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
QI63_RS03320	COG1847	R3H domain protein
QI63_RS03325	COG0706	membrane insertase activity
QI63_RS03360	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
QI63_RS03365	COG1472	Belongs to the glycosyl hydrolase 3 family
QI63_RS03370	COG0492	ferredoxin-NADP+ reductase activity
QI63_RS03375	COG0280	phosphate acetyltransferase
QI63_RS03395	COG1151	hydroxylamine reductase activity
QI63_RS03415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
QI63_RS03420	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
QI63_RS03425	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
QI63_RS03425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
QI63_RS03440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
QI63_RS03455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
QI63_RS03495	COG0728	peptidoglycan biosynthetic process
QI63_RS03510	COG0803	Belongs to the bacterial solute-binding protein 9 family
QI63_RS03520	COG0419	ATPase involved in DNA repair
QI63_RS03530	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
QI63_RS03615	COG4443	Transcriptional Coactivator p15 (PC4)
QI63_RS03620	COG0840	transmembrane signaling receptor activity
QI63_RS03630	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
QI63_RS03630	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
QI63_RS03635	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
QI63_RS03655	COG1309	transcriptional regulator
QI63_RS03680	COG1647	Serine aminopeptidase, S33
QI63_RS03690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
QI63_RS03695	COG1028	Short-chain dehydrogenase reductase Sdr
QI63_RS03700	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
QI63_RS03705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
QI63_RS03725	COG0291	Belongs to the bacterial ribosomal protein bL35 family
QI63_RS03740	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
QI63_RS03745	COG1671	Belongs to the UPF0178 family
QI63_RS03750	COG3437	response regulator, receiver
QI63_RS03755	COG2195	Cleaves the N-terminal amino acid of tripeptides
QI63_RS03760	COG1115	amino acid carrier protein
QI63_RS03765	COG0511	ligase activity, forming carbon-carbon bonds
QI63_RS03765	COG5016	pyruvate
QI63_RS03770	COG1472	Belongs to the glycosyl hydrolase 3 family
QI63_RS03780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
QI63_RS03795	COG0778	Nitroreductase
QI63_RS03800	COG1131	(ABC) transporter
QI63_RS03820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
QI63_RS03865	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
QI63_RS03870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
QI63_RS03885	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
QI63_RS03895	COG3608	succinylglutamate desuccinylase aspartoacylase
QI63_RS03895	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
QI63_RS03910	COG1121	(ABC) transporter
QI63_RS03915	COG1639	'signal transduction protein
QI63_RS03920	COG0543	2 iron, 2 sulfur cluster binding
QI63_RS03935	COG0733	neurotransmitter:sodium symporter activity
QI63_RS03945	COG1744	ABC transporter substrate-binding protein PnrA-like
QI63_RS03950	COG1129	ABC transporter
QI63_RS03955	COG4603	Belongs to the binding-protein-dependent transport system permease family
QI63_RS03960	COG1079	Belongs to the binding-protein-dependent transport system permease family
QI63_RS03965	COG4942	peptidase
QI63_RS03980	COG3177	Filamentation induced by cAMP protein fic
QI63_RS03990	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
QI63_RS04000	COG4536	flavin adenine dinucleotide binding
QI63_RS04010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
QI63_RS04015	COG0542	response to heat
QI63_RS04035	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
QI63_RS04045	COG0450	alkyl hydroperoxide reductase
QI63_RS04050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
QI63_RS04095	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
QI63_RS04125	COG0793	Belongs to the peptidase S41A family
QI63_RS04170	COG0203	ribosomal protein L17
QI63_RS04175	COG0202	RNA polymerase activity
QI63_RS04180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
QI63_RS04190	COG0257	Belongs to the bacterial ribosomal protein bL36 family
QI63_RS04200	COG0200	Binds to the 23S rRNA
QI63_RS04210	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
QI63_RS04220	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
QI63_RS04225	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
QI63_RS04230	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
QI63_RS04235	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
QI63_RS04240	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
QI63_RS04245	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
QI63_RS04250	COG0255	Belongs to the universal ribosomal protein uL29 family
QI63_RS04260	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
QI63_RS04265	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
QI63_RS04275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
QI63_RS04280	COG0089	rRNA binding
QI63_RS04285	COG0088	Forms part of the polypeptide exit tunnel
QI63_RS04290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
QI63_RS04295	COG0051	transcription antitermination factor activity, RNA binding
QI63_RS04300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
QI63_RS04340	COG1968	undecaprenyl-diphosphatase activity
QI63_RS04345	COG1674	ftsk spoiiie
QI63_RS04365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
QI63_RS04375	COG0084	hydrolase, TatD family'
QI63_RS04385	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
QI63_RS04430	COG0714	Associated with various cellular activities
QI63_RS04470	COG2425	protein containing a von Willebrand factor type A (vWA) domain
QI63_RS04480	COG1373	ATPase (AAA superfamily
QI63_RS04490	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
QI63_RS04500	COG3842	ATPase activity
QI63_RS04505	COG1178	ABC-type Fe3 transport system permease component
QI63_RS04510	COG3842	ATPase activity
QI63_RS04520	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
QI63_RS04530	COG4750	Nucleotidyl transferase
QI63_RS04535	COG2211	Major facilitator Superfamily
QI63_RS04545	COG1640	4-alpha-glucanotransferase
QI63_RS04565	COG0019	diaminopimelate decarboxylase activity
QI63_RS04570	COG0716	FMN binding
QI63_RS04580	COG1956	GAF domain-containing protein
QI63_RS04595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
QI63_RS04600	COG1136	(ABC) transporter
QI63_RS04605	COG0577	efflux transmembrane transporter activity
QI63_RS04605	COG1136	(ABC) transporter
QI63_RS04610	COG1136	(ABC) transporter
QI63_RS04610	COG0577	efflux transmembrane transporter activity
QI63_RS04645	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
QI63_RS04655	COG1132	(ABC) transporter
QI63_RS04660	COG4115	mRNA cleavage
QI63_RS04710	COG1002	Type II restriction enzyme, methylase subunits
QI63_RS04715	COG2378	regulation of single-species biofilm formation
QI63_RS04725	COG1132	(ABC) transporter
QI63_RS04735	COG1162	GTPase activity
QI63_RS04740	COG1309	transcriptional regulator
QI63_RS04750	COG1132	(ABC) transporter
QI63_RS04755	COG1132	(ABC) transporter
QI63_RS04760	COG1129	ABC transporter
QI63_RS04775	COG1132	(ABC) transporter
QI63_RS04780	COG1132	(ABC) transporter
QI63_RS04805	COG2217	Heavy metal translocating P-type atpase
QI63_RS04810	COG0640	Transcriptional regulator
QI63_RS04815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
QI63_RS04835	COG1529	Aldehyde oxidase and xanthine dehydrogenase
QI63_RS04840	COG0326	Molecular chaperone. Has ATPase activity
QI63_RS04845	COG0012	GTP binding
QI63_RS04850	COG2183	response to ionizing radiation
QI63_RS04865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
QI63_RS04870	COG0423	glycine-tRNA ligase activity
QI63_RS04880	COG0584	glycerophosphoryl diester phosphodiesterase
QI63_RS04885	COG2949	membrane
QI63_RS04915	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
QI63_RS04915	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
QI63_RS04925	COG0116	Belongs to the methyltransferase superfamily
QI63_RS04930	COG0701	Predicted permease
QI63_RS05005	COG0425	Belongs to the sulfur carrier protein TusA family
QI63_RS05015	COG0709	Synthesizes selenophosphate from selenide and ATP
QI63_RS05035	COG0488	(ABC) transporter
QI63_RS05060	COG1054	Belongs to the UPF0176 family
QI63_RS05065	COG0024	Methionine aminopeptidase
QI63_RS05070	COG0484	heat shock protein binding
QI63_RS05090	COG3706	GGDEF domain
QI63_RS05095	COG5001	Diguanylate cyclase
QI63_RS05100	COG1757	Na H antiporter
QI63_RS05120	COG0863	Belongs to the N(4) N(6)-methyltransferase family
QI63_RS05210	COG2089	acid synthase
QI63_RS05215	COG0592	DNA-directed DNA polymerase activity
QI63_RS05240	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
QI63_RS05250	COG0545	Peptidyl-prolyl cis-trans isomerase
QI63_RS05255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
QI63_RS05285	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
QI63_RS05290	COG0739	heme binding
QI63_RS05295	COG1686	Belongs to the peptidase S11 family
QI63_RS05315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
QI63_RS05320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
QI63_RS05400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
QI63_RS05455	COG2204	response regulator
QI63_RS05460	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
QI63_RS05465	COG1028	Short-chain dehydrogenase reductase Sdr
QI63_RS05475	COG0516	GMP reductase activity
QI63_RS05475	COG0517	IMP dehydrogenase activity
QI63_RS05480	COG0205	6-phosphofructokinase activity
QI63_RS05490	COG3842	ATPase activity
QI63_RS05495	COG1176	ABC-type spermidine putrescine transport system, permease component I
QI63_RS05500	COG1177	transmembrane transport
QI63_RS05530	COG1120	ATPase activity
QI63_RS05535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QI63_RS05575	COG0156	8-amino-7-oxononanoate synthase activity
QI63_RS05580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
QI63_RS05590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
QI63_RS05595	COG2759	Belongs to the formate--tetrahydrofolate ligase family
QI63_RS05600	COG1114	Component of the transport system for branched-chain amino acids
QI63_RS05605	COG0840	transmembrane signaling receptor activity
QI63_RS05610	COG0739	heme binding
QI63_RS05615	COG2885	chlorophyll binding
QI63_RS05620	COG0237	dephospho-CoA kinase activity
QI63_RS05640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
QI63_RS05660	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
QI63_RS05665	COG1640	4-alpha-glucanotransferase
QI63_RS05670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
QI63_RS05730	COG1983	PspC domain protein
QI63_RS05740	COG1695	Transcriptional regulator
QI63_RS05755	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
QI63_RS05765	COG0445	tRNA wobble uridine modification
QI63_RS05775	COG2255	four-way junction helicase activity
QI63_RS05785	COG0822	iron-sulfur transferase activity
QI63_RS05795	COG0826	peptidase U32
QI63_RS05830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
QI63_RS05835	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
QI63_RS05855	COG0739	heme binding
QI63_RS05885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
QI63_RS05890	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
QI63_RS05910	COG0732	type I restriction modification DNA specificity domain
QI63_RS05915	COG4974	Belongs to the 'phage' integrase family
QI63_RS05940	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
QI63_RS05965	COG0840	transmembrane signaling receptor activity
QI63_RS05975	COG0737	Belongs to the 5'-nucleotidase family
QI63_RS06015	COG0351	phosphomethylpyrimidine kinase
QI63_RS06025	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
QI63_RS06025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
QI63_RS06040	COG0745	RESPONSE REGULATOR receiver
QI63_RS06045	COG3850	Histidine kinase
QI63_RS06045	COG5002	protein histidine kinase activity
QI63_RS06055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
QI63_RS06065	COG2011	ABC-type metal ion transport system permease component
QI63_RS06075	COG1879	ABC-type sugar transport system periplasmic component
QI63_RS06085	COG1172	Belongs to the binding-protein-dependent transport system permease family
QI63_RS06100	COG1070	Carbohydrate kinase
QI63_RS06115	COG1175	transmembrane transport
QI63_RS06120	COG0395	ABC-type sugar transport system, permease component
QI63_RS06125	COG0513	Belongs to the DEAD box helicase family
QI63_RS06135	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
QI63_RS06175	COG0039	L-malate dehydrogenase activity
QI63_RS06180	COG0281	malic enzyme
QI63_RS06190	COG0629	single-stranded DNA binding
QI63_RS06225	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
QI63_RS06235	COG1193	negative regulation of DNA recombination
QI63_RS06255	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
QI63_RS06265	COG0613	PHP domain protein
QI63_RS06275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
QI63_RS06410	COG0825	malonyl-CoA metabolic process
QI63_RS06415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
QI63_RS06425	COG0511	ligase activity, forming carbon-carbon bonds
QI63_RS06430	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
QI63_RS06435	COG4656	Part of a membrane complex involved in electron transport
QI63_RS06440	COG4658	electron transport chain
QI63_RS06445	COG4659	FMN binding
QI63_RS06450	COG4660	Part of a membrane complex involved in electron transport
QI63_RS06455	COG4657	Part of a membrane complex involved in electron transport
QI63_RS06460	COG2878	Part of a membrane complex involved in electron transport
QI63_RS06465	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
QI63_RS06470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
QI63_RS06475	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
QI63_RS06480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
QI63_RS06515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
QI63_RS06530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
QI63_RS06545	COG0653	protein targeting
QI63_RS06605	COG0698	ribose 5-phosphate isomerase
QI63_RS06620	COG1733	regulation of RNA biosynthetic process
QI63_RS06665	COG1722	exodeoxyribonuclease VII activity
QI63_RS06670	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
QI63_RS06675	COG0433	COG0433 Predicted ATPase
QI63_RS06690	COG1193	negative regulation of DNA recombination
QI63_RS06710	COG1254	Belongs to the acylphosphatase family
QI63_RS06725	COG2217	Heavy metal translocating P-type atpase
QI63_RS06750	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
QI63_RS06750	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
QI63_RS06760	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
QI63_RS06775	COG3052	prosthetic group binding
QI63_RS06780	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
QI63_RS06820	COG1191	sigma factor activity
QI63_RS06840	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
QI63_RS06860	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
QI63_RS06865	COG0180	Tryptophanyl-tRNA synthetase
QI63_RS06875	COG0670	Belongs to the BI1 family
QI63_RS06885	COG2604	Protein of unknown function DUF115
QI63_RS06890	COG0768	penicillin binding
QI63_RS07145	COG0494	nUDIX hydrolase
QI63_RS07170	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
QI63_RS07175	COG0457	Tetratricopeptide repeat
QI63_RS07185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
QI63_RS07190	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
QI63_RS07210	COG0402	S-adenosylhomocysteine deaminase activity
QI63_RS07215	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
QI63_RS07220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
QI63_RS07225	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
QI63_RS07235	COG2207	Transcriptional regulator
QI63_RS07235	COG3708	Transcriptional regulator
QI63_RS07250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
QI63_RS07265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
QI63_RS07275	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
QI63_RS07285	COG1199	ATP-dependent helicase activity
QI63_RS07305	COG0840	transmembrane signaling receptor activity
QI63_RS07315	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
QI63_RS07345	COG1269	ATP hydrolysis coupled proton transport
QI63_RS07350	COG1394	ATPase activity, coupled to movement of substances
QI63_RS07355	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
QI63_RS07360	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
QI63_RS07370	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
QI63_RS07385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
QI63_RS07390	COG0346	lactoylglutathione lyase activity
QI63_RS07395	COG1881	PFAM PEBP family protein
QI63_RS07400	COG3340	Belongs to the peptidase S51 family
QI63_RS07420	COG4221	oxidoreductase activity
QI63_RS07420	COG3321	synthase
QI63_RS07420	COG0604	alcohol dehydrogenase
QI63_RS07420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
QI63_RS07455	COG2267	carboxylic ester hydrolase activity
QI63_RS07490	COG2249	NAD(P)H dehydrogenase (quinone) activity
QI63_RS07495	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
QI63_RS07500	COG0483	inositol monophosphate 1-phosphatase activity
QI63_RS07505	COG3842	ATPase activity
QI63_RS07525	COG1846	Transcriptional regulator
QI63_RS07540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
QI63_RS07545	COG0674	pyruvate-flavodoxin oxidoreductase activity
QI63_RS07545	COG1013	pyruvate-flavodoxin oxidoreductase activity
QI63_RS07545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
QI63_RS07545	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
QI63_RS07550	COG0513	Belongs to the DEAD box helicase family
QI63_RS07555	COG2195	Cleaves the N-terminal amino acid of tripeptides
QI63_RS07575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
QI63_RS07590	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
QI63_RS07595	COG0443	Heat shock 70 kDa protein
QI63_RS07600	COG0484	heat shock protein binding
QI63_RS07625	COG1205	dead DEAH box helicase
QI63_RS07625	COG1111	helicase
QI63_RS07645	COG0617	tRNA 3'-terminal CCA addition
QI63_RS07650	COG1194	a g-specific adenine glycosylase
QI63_RS07655	COG1102	Psort location Cytoplasmic, score
QI63_RS07685	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
QI63_RS07980	COG0629	single-stranded DNA binding
QI63_RS08020	COG0544	peptidyl-prolyl cis-trans isomerase activity
QI63_RS08025	COG0740	serine-type endopeptidase activity
QI63_RS08030	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
QI63_RS08040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
QI63_RS08060	COG2267	carboxylic ester hydrolase activity
QI63_RS08075	COG0481	GTPase activity
QI63_RS08080	COG0018	arginyl-trna synthetase
QI63_RS08095	COG2235	arginine
QI63_RS08100	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
QI63_RS08105	COG0549	Belongs to the carbamate kinase family
QI63_RS08110	COG1288	antiporter activity
QI63_RS08120	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
QI63_RS08125	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
QI63_RS08130	COG0017	Asparaginyl-tRNA synthetase
QI63_RS08145	COG1733	regulation of RNA biosynthetic process
QI63_RS08210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
QI63_RS08225	COG3118	belongs to the thioredoxin family
QI63_RS08230	COG1692	metallophosphoesterase
QI63_RS08235	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
QI63_RS08245	COG0719	Fe-S assembly protein
QI63_RS08285	COG1570	exodeoxyribonuclease VII activity
QI63_RS08295	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
QI63_RS08300	COG0740	serine-type endopeptidase activity
QI63_RS08325	COG0681	Belongs to the peptidase S26 family
QI63_RS08330	COG0840	transmembrane signaling receptor activity
QI63_RS08355	COG2885	chlorophyll binding
QI63_RS08360	COG0300	oxidoreductase activity
QI63_RS08370	COG2887	Belongs to the helicase family. UvrD subfamily
QI63_RS08390	COG1960	acyl-CoA dehydrogenase activity
QI63_RS08395	COG1012	belongs to the aldehyde dehydrogenase family
QI63_RS08405	COG1385	rRNA (uridine-N3-)-methyltransferase activity
QI63_RS08420	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
QI63_RS08450	COG4786	Flagellar basal body rod
QI63_RS08460	COG3951	Flagellar rod assembly protein muramidase FlgJ
QI63_RS08475	COG1120	ATPase activity
QI63_RS08480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QI63_RS08510	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
QI63_RS08540	COG0251	oxidation-reduction process
QI63_RS08555	COG1047	Peptidyl-prolyl cis-trans
QI63_RS08560	COG0261	This protein binds to 23S rRNA in the presence of protein L20
QI63_RS08570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
QI63_RS08575	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
QI63_RS08585	COG1713	HD superfamily hydrolase involved in NAD metabolism
QI63_RS08585	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
QI63_RS08605	COG0779	Required for maturation of 30S ribosomal subunits
QI63_RS08615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
QI63_RS08620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
QI63_RS08630	COG0196	riboflavin kinase activity
QI63_RS08640	COG1185	polyribonucleotide nucleotidyltransferase activity
QI63_RS08645	COG0756	dUTP diphosphatase activity
QI63_RS08660	COG0840	transmembrane signaling receptor activity
QI63_RS08665	COG1253	flavin adenine dinucleotide binding
QI63_RS08680	COG0840	transmembrane signaling receptor activity
QI63_RS08680	COG3290	protein histidine kinase activity
QI63_RS08690	COG0546	phosphoglycolate phosphatase activity
QI63_RS08700	COG1609	Transcriptional regulator
QI63_RS08705	COG1129	ABC transporter
QI63_RS08725	COG1187	pseudouridine synthase activity
QI63_RS08745	COG3639	organic phosphonate transmembrane transporter activity
QI63_RS08750	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
QI63_RS08765	COG0813	purine-nucleoside phosphorylase activity
QI63_RS08820	COG2703	oxygen carrier activity
QI63_RS08825	COG1523	belongs to the glycosyl hydrolase 13 family
QI63_RS08830	COG2182	Extracellular solute-binding protein
QI63_RS08845	COG1175	transmembrane transport
QI63_RS08850	COG3833	ABC-type maltose transport systems, permease component
QI63_RS08860	COG0210	DNA helicase
QI63_RS08870	COG1979	alcohol dehydrogenase
QI63_RS08885	COG0698	ribose 5-phosphate isomerase
QI63_RS08895	COG2375	cellular response to nickel ion
QI63_RS08895	COG1132	(ABC) transporter
QI63_RS08900	COG1132	(ABC) transporter
QI63_RS08925	COG2226	methyltransferase
QI63_RS08995	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
QI63_RS09010	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
QI63_RS09015	COG1360	Flagellar Motor Protein
QI63_RS09020	COG1580	Controls the rotational direction of flagella during chemotaxis
QI63_RS09025	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
QI63_RS09030	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
QI63_RS09030	COG1776	CheC inhibitor of MCP methylation
QI63_RS09040	COG1338	Plays a role in the flagellum-specific transport system
QI63_RS09045	COG1987	bacterial-type flagellum assembly
QI63_RS09055	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
QI63_RS09060	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
QI63_RS09065	COG1419	protein localization to endoplasmic reticulum
QI63_RS09075	COG1215	transferase activity, transferring glycosyl groups
QI63_RS09080	COG0534	Mate efflux family protein
QI63_RS09090	COG0557	exoribonuclease II activity
QI63_RS09095	COG1362	aminopeptidase activity
QI63_RS09105	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
QI63_RS09105	COG3608	succinylglutamate desuccinylase aspartoacylase
QI63_RS09110	COG0587	DNA-directed DNA polymerase activity
QI63_RS09120	COG4211	Belongs to the binding-protein-dependent transport system permease family
QI63_RS09125	COG1129	ABC transporter
QI63_RS09130	COG1879	ABC-type sugar transport system periplasmic component
QI63_RS09135	COG0525	valine-tRNA ligase activity
QI63_RS09155	COG2604	Protein of unknown function DUF115
QI63_RS09180	COG4974	Belongs to the 'phage' integrase family
QI63_RS09185	COG0551	DNA topoisomerase type I activity
QI63_RS09185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
QI63_RS09190	COG0758	DNA mediated transformation
QI63_RS09200	COG0475	glutathione-regulated potassium exporter activity
QI63_RS09210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
QI63_RS09215	COG0672	)-iron permease
QI63_RS09220	COG3470	protein probably involved in high-affinity Fe2 transport
QI63_RS09235	COG0577	efflux transmembrane transporter activity
QI63_RS09235	COG1136	(ABC) transporter
QI63_RS09240	COG1136	(ABC) transporter
QI63_RS09255	COG0488	(ABC) transporter
QI63_RS09275	COG2226	methyltransferase
QI63_RS09315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
QI63_RS09320	COG0840	transmembrane signaling receptor activity
QI63_RS09330	COG0514	ATP-dependent DNA helicase (RecQ)
QI63_RS09340	COG0737	Belongs to the 5'-nucleotidase family
QI63_RS09350	COG1022	Amp-dependent synthetase and ligase
QI63_RS09355	COG0537	adenosine 5'-monophosphoramidase activity
QI63_RS09360	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
QI63_RS09365	COG2088	sporulation resulting in formation of a cellular spore
QI63_RS09375	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
QI63_RS09380	COG0037	tRNA processing
QI63_RS09385	COG0457	Tetratricopeptide repeat
QI63_RS09405	COG0840	transmembrane signaling receptor activity
QI63_RS09410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
QI63_RS09415	COG0786	glutamate:sodium symporter activity
QI63_RS09430	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
QI63_RS09435	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
QI63_RS09440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
QI63_RS09445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
QI63_RS09450	COG0786	glutamate:sodium symporter activity
QI63_RS09455	COG1924	4 iron, 4 sulfur cluster binding
QI63_RS09460	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
QI63_RS09465	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
QI63_RS09475	COG0735	belongs to the Fur family
QI63_RS09490	COG0494	nUDIX hydrolase
QI63_RS09510	COG1480	7TM receptor with intracellular HD hydrolase
QI63_RS09515	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
QI63_RS09545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
QI63_RS09545	COG0426	domain, Protein
QI63_RS09550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
QI63_RS09560	COG0318	PFAM AMP-dependent synthetase and ligase
QI63_RS09565	COG1283	sodium-dependent phosphate transmembrane transporter activity
QI63_RS09570	COG0574	Belongs to the PEP-utilizing enzyme family
QI63_RS09570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
QI63_RS09610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
QI63_RS09620	COG0126	phosphoglycerate kinase activity
QI63_RS09660	COG2201	protein-glutamate methylesterase activity
QI63_RS09675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
QI63_RS09680	COG0812	UDP-N-acetylmuramate dehydrogenase activity
QI63_RS09685	COG0215	cysteine-tRNA ligase activity
QI63_RS09705	COG0528	UMP kinase activity
QI63_RS09710	COG0484	heat shock protein binding
QI63_RS09715	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
QI63_RS09735	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
QI63_RS09755	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
QI63_RS09760	COG3118	belongs to the thioredoxin family
QI63_RS09765	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
QI63_RS09765	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
QI63_RS09790	COG0218	Necessary for normal cell division and for the maintenance of normal septation
QI63_RS09795	COG0166	Belongs to the GPI family
QI63_RS09800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
QI63_RS09820	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
QI63_RS09830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
QI63_RS09850	COG2304	oxidoreductase activity
QI63_RS09860	COG0183	Belongs to the thiolase family
QI63_RS09875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
QI63_RS09875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
QI63_RS09880	COG1129	ABC transporter
QI63_RS09895	COG1917	Cupin 2, conserved barrel domain protein
QI63_RS09895	COG4977	sequence-specific DNA binding
QI63_RS09910	COG1129	ABC transporter
QI63_RS09920	COG2375	cellular response to nickel ion
QI63_RS09920	COG1132	(ABC) transporter
QI63_RS09950	COG1132	(ABC) transporter
QI63_RS09970	COG1129	ABC transporter
QI63_RS10005	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
QI63_RS10015	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
QI63_RS10040	COG0519	Catalyzes the synthesis of GMP from XMP
QI63_RS10045	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
QI63_RS10060	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
QI63_RS10075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
QI63_RS10085	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
QI63_RS10100	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
QI63_RS10105	COG1472	Belongs to the glycosyl hydrolase 3 family
QI63_RS10110	COG3876	Protein conserved in bacteria
QI63_RS10120	COG2885	chlorophyll binding
QI63_RS10125	COG0741	lytic transglycosylase activity
QI63_RS10125	COG1388	LysM domain
QI63_RS10175	COG3189	MarR family transcriptional regulator
QI63_RS10200	COG0358	DNA primase activity
QI63_RS10205	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
QI63_RS10220	COG1077	Cell shape determining protein MreB Mrl
QI63_RS10235	COG0768	penicillin binding
QI63_RS10240	COG0772	Belongs to the SEDS family
QI63_RS10250	COG0563	adenylate kinase activity
QI63_RS10255	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
QI63_RS10260	COG1131	(ABC) transporter
QI63_RS10275	COG2357	RelA SpoT domain protein
QI63_RS10280	COG1132	(ABC) transporter
QI63_RS10290	COG1132	(ABC) transporter
QI63_RS10290	COG2375	cellular response to nickel ion
QI63_RS10330	COG1301	dicarboxylic acid transport
QI63_RS10350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
QI63_RS10360	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
QI63_RS10370	COG0455	bacterial-type flagellum organization
QI63_RS10380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
QI63_RS10385	COG0330	HflC and HflK could
QI63_RS10390	COG0330	HflC and HflK could
QI63_RS10430	COG0564	pseudouridine synthase activity
QI63_RS10435	COG0285	dihydrofolate synthase activity
QI63_RS10440	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
QI63_RS10450	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
QI63_RS10470	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
QI63_RS10475	COG1132	(ABC) transporter
QI63_RS10480	COG4988	ABC transporter
QI63_RS10485	COG3842	ATPase activity
QI63_RS10510	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
QI63_RS10510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
QI63_RS10510	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
QI63_RS10515	COG0504	CTP synthase activity
QI63_RS10540	COG0482	sulfurtransferase activity
QI63_RS10550	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
QI63_RS10555	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
QI63_RS10560	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
QI63_RS10570	COG0318	PFAM AMP-dependent synthetase and ligase
QI63_RS10575	COG0791	NLP P60 protein
QI63_RS10580	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
QI63_RS10605	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
QI63_RS10645	COG0497	DNA recombination
QI63_RS10650	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
QI63_RS10655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
QI63_RS10660	COG0835	chemotaxis
QI63_RS10670	COG5341	Protein conserved in bacteria
QI63_RS10685	COG0442	prolyl-tRNA aminoacylation
QI63_RS10695	COG0424	maF-like protein
QI63_RS10700	COG0052	Belongs to the universal ribosomal protein uS2 family
QI63_RS10705	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
QI63_RS10710	COG0233	cytoplasmic translational termination
QI63_RS10715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
QI63_RS10720	COG0575	Belongs to the CDS family
QI63_RS10725	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
QI63_RS10730	COG0750	zinc metalloprotease
QI63_RS10745	COG1309	transcriptional regulator
QI63_RS10755	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
QI63_RS10780	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
QI63_RS10785	COG0714	Associated with various cellular activities
QI63_RS10800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
QI63_RS10805	COG2890	protein-(glutamine-N5) methyltransferase activity
QI63_RS10810	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
QI63_RS10815	COG0666	response to abiotic stimulus
QI63_RS10825	COG3330	Domain of unknown function (DUF4912)
QI63_RS10830	COG1543	Belongs to the glycosyl hydrolase 57 family
QI63_RS10835	COG0588	phosphoglycerate mutase activity
QI63_RS10840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
QI63_RS10850	COG1131	(ABC) transporter
QI63_RS10880	COG1760	l-serine dehydratase
QI63_RS10885	COG1760	l-serine dehydratase
QI63_RS10890	COG0149	triose-phosphate isomerase activity
QI63_RS10905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
QI63_RS10910	COG2011	ABC-type metal ion transport system permease component
QI63_RS10915	COG1464	Belongs to the NlpA lipoprotein family
QI63_RS10920	COG1473	amidohydrolase
QI63_RS10955	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
QI63_RS10970	COG0577	efflux transmembrane transporter activity
QI63_RS10970	COG1136	(ABC) transporter
QI63_RS10975	COG1136	(ABC) transporter
QI63_RS10985	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
QI63_RS11000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
QI63_RS11005	COG1509	lysine 2,3-aminomutase activity
QI63_RS11030	COG0193	aminoacyl-tRNA hydrolase activity
QI63_RS11035	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
QI63_RS11045	COG1136	(ABC) transporter
QI63_RS11065	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
QI63_RS11105	COG1222	aaa ATPase
QI63_RS11120	COG1132	(ABC) transporter
QI63_RS11140	COG1129	ABC transporter
QI63_RS11145	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
QI63_RS11150	COG3681	Belongs to the UPF0597 family
QI63_RS11165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
QI63_RS11170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
QI63_RS11175	COG1120	ATPase activity
QI63_RS11185	COG1132	(ABC) transporter
QI63_RS11195	COG1704	LemA family
QI63_RS11210	COG1132	(ABC) transporter
QI63_RS11215	COG1132	(ABC) transporter
QI63_RS11220	COG1802	Transcriptional regulator
QI63_RS11225	COG0632	four-way junction helicase activity
QI63_RS11230	COG1739	Uncharacterized protein family UPF0029
QI63_RS11235	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
QI63_RS11240	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
QI63_RS11250	COG0470	DNA polymerase III
QI63_RS11265	COG0305	Participates in initiation and elongation during chromosome replication
QI63_RS11270	COG0359	binds to the 23S rRNA
QI63_RS11275	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
QI63_RS11280	COG0629	single-stranded DNA binding
QI63_RS11285	COG0360	Binds together with S18 to 16S ribosomal RNA
QI63_RS11290	COG0523	cobalamin synthesis protein
QI63_RS11295	COG0534	Mate efflux family protein
QI63_RS11310	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
QI63_RS11315	COG1104	cysteine desulfurase activity
QI63_RS11320	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
QI63_RS11330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
QI63_RS11365	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
QI63_RS11370	COG1321	iron dependent repressor
QI63_RS11375	COG0803	Belongs to the bacterial solute-binding protein 9 family
QI63_RS11380	COG1121	(ABC) transporter
QI63_RS11385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
QI63_RS11390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
QI63_RS11395	COG1683	Conserved Protein
QI63_RS11405	COG3869	Catalyzes the specific phosphorylation of arginine residues in
QI63_RS11415	COG3290	protein histidine kinase activity
QI63_RS11415	COG3829	transcription factor binding
QI63_RS11425	COG3852	Histidine kinase
QI63_RS11430	COG2204	response regulator
QI63_RS11435	COG0823	Involved in the tonB-independent uptake of proteins
QI63_RS11470	COG0427	acetyl-CoA hydrolase
QI63_RS11475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
QI63_RS11480	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
QI63_RS11505	COG1454	alcohol dehydrogenase
QI63_RS11520	COG0708	Exodeoxyribonuclease III
QI63_RS11530	COG2832	Protein of unknown function (DUF454)
QI63_RS11535	COG1137	ATPase activity
QI63_RS11545	COG2217	Heavy metal translocating P-type atpase
QI63_RS11565	COG0402	S-adenosylhomocysteine deaminase activity
QI63_RS11580	COG1120	ATPase activity
QI63_RS11605	COG0357	Ribosomal RNA small subunit methyltransferase G
QI63_RS11615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
QI63_RS11620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
QI63_RS11650	COG0457	Tetratricopeptide repeat
QI63_RS11655	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
QI63_RS11660	COG0733	neurotransmitter:sodium symporter activity
QI63_RS11665	COG1233	COG1233 Phytoene dehydrogenase and related
QI63_RS11670	COG1562	ergosterol biosynthetic process
QI63_RS11675	COG0170	dolichyl monophosphate biosynthetic process
QI63_RS11680	COG1196	nuclear chromosome segregation
QI63_RS11690	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
QI63_RS11695	COG0724	RNA recognition motif
QI63_RS11710	COG4953	penicillin-binding protein 1C
QI63_RS11715	COG1373	ATPase (AAA superfamily
QI63_RS11930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
QI63_RS11935	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
QI63_RS11950	COG1136	(ABC) transporter
QI63_RS11955	COG4591	ABC-type transport system involved in lipoprotein release permease component
QI63_RS11965	COG0552	protein localization to endoplasmic reticulum
QI63_RS11975	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
QI63_RS11990	COG1122	ATPase activity
QI63_RS11995	COG1268	BioY protein
QI63_RS12005	COG0446	pyridine nucleotide-disulphide oxidoreductase
QI63_RS12010	COG1876	peptidase activity
QI63_RS12040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
QI63_RS12045	COG0601	transmembrane transport
QI63_RS12050	COG4608	Belongs to the ABC transporter superfamily
QI63_RS12060	COG0561	phosphatase activity
QI63_RS12065	COG0436	Aminotransferase
QI63_RS12070	COG1522	sequence-specific DNA binding
QI63_RS12080	COG0101	tRNA pseudouridine synthase activity
QI63_RS12090	COG0736	holo-[acyl-carrier-protein] synthase activity
QI63_RS12100	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
QI63_RS12105	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
QI63_RS12365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
QI63_RS12370	COG2003	Belongs to the UPF0758 family
QI63_RS12395	COG0714	Associated with various cellular activities
QI63_RS12465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
QI63_RS12490	COG1132	(ABC) transporter