locus-tag	class	description
TRESU_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TRESU_RS00010	COG0592	DNA-directed DNA polymerase activity
TRESU_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TRESU_RS00025	COG0230	Belongs to the bacterial ribosomal protein bL34 family
TRESU_RS00035	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TRESU_RS00040	COG0706	membrane insertase activity
TRESU_RS00045	COG1847	R3H domain protein
TRESU_RS00055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TRESU_RS00070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TRESU_RS00075	COG0295	cytidine deaminase activity
TRESU_RS00080	COG1534	Rna-binding protein
TRESU_RS00100	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TRESU_RS00115	COG3216	Uncharacterized protein conserved in bacteria (DUF2062)
TRESU_RS00135	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TRESU_RS00135	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TRESU_RS00145	COG1346	cytolysis
TRESU_RS00150	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TRESU_RS00155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TRESU_RS00165	COG0534	Mate efflux family protein
TRESU_RS00170	COG2885	chlorophyll binding
TRESU_RS00175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TRESU_RS00180	COG0583	DNA-binding transcription factor activity
TRESU_RS00200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TRESU_RS00205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TRESU_RS00215	COG1253	flavin adenine dinucleotide binding
TRESU_RS00220	COG4536	flavin adenine dinucleotide binding
TRESU_RS00230	COG0564	pseudouridine synthase activity
TRESU_RS00235	COG1120	ATPase activity
TRESU_RS00240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TRESU_RS00270	COG0395	ABC-type sugar transport system, permease component
TRESU_RS00275	COG3507	Belongs to the glycosyl hydrolase 43 family
TRESU_RS00290	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TRESU_RS00295	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TRESU_RS00310	COG0501	Belongs to the peptidase M48B family
TRESU_RS00315	COG0357	Ribosomal RNA small subunit methyltransferase G
TRESU_RS00330	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
TRESU_RS00335	COG3409	Peptidoglycan-binding domain 1 protein
TRESU_RS00335	COG0793	Belongs to the peptidase S41A family
TRESU_RS00340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TRESU_RS00355	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
TRESU_RS00365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TRESU_RS00375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TRESU_RS00415	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TRESU_RS00420	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
TRESU_RS00430	COG1268	BioY protein
TRESU_RS00445	COG0583	DNA-binding transcription factor activity
TRESU_RS00475	COG0697	spore germination
TRESU_RS00480	COG0493	'glutamate synthase
TRESU_RS00505	COG1285	pathogenesis
TRESU_RS00525	COG0433	COG0433 Predicted ATPase
TRESU_RS00530	COG0534	Mate efflux family protein
TRESU_RS00550	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS00575	COG5433	transposase activity
TRESU_RS00610	COG0488	(ABC) transporter
TRESU_RS00635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TRESU_RS00635	COG0574	Belongs to the PEP-utilizing enzyme family
TRESU_RS00640	COG3800	Transcriptional regulator
TRESU_RS00640	COG1396	sequence-specific DNA binding
TRESU_RS00670	COG0071	Belongs to the small heat shock protein (HSP20) family
TRESU_RS00680	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TRESU_RS00685	COG0367	asparagine synthase
TRESU_RS00695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
TRESU_RS00710	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TRESU_RS00720	COG0601	transmembrane transport
TRESU_RS00730	COG0444	Belongs to the ABC transporter superfamily
TRESU_RS00735	COG4608	Belongs to the ABC transporter superfamily
TRESU_RS00745	COG1328	CTP reductase activity
TRESU_RS00745	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TRESU_RS00750	COG0602	queuosine metabolic process
TRESU_RS00825	COG0318	PFAM AMP-dependent synthetase and ligase
TRESU_RS00845	COG0708	Exodeoxyribonuclease III
TRESU_RS00855	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
TRESU_RS00870	COG2195	Cleaves the N-terminal amino acid of tripeptides
TRESU_RS00875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TRESU_RS00880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TRESU_RS00890	COG0791	NLP P60 protein
TRESU_RS00895	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
TRESU_RS00900	COG3507	Belongs to the glycosyl hydrolase 43 family
TRESU_RS00900	COG3693	PFAM glycoside hydrolase, family 10
TRESU_RS00900	COG2382	esterase
TRESU_RS00940	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TRESU_RS00945	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TRESU_RS00960	COG0587	DNA-directed DNA polymerase activity
TRESU_RS00965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TRESU_RS00975	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TRESU_RS00980	COG1752	Esterase of the alpha-beta hydrolase superfamily
TRESU_RS00990	COG2183	response to ionizing radiation
TRESU_RS01050	COG3177	Filamentation induced by cAMP protein fic
TRESU_RS01055	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
TRESU_RS01070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TRESU_RS01085	COG0504	CTP synthase activity
TRESU_RS01110	COG1216	Glycosyl transferase, family 2
TRESU_RS01110	COG1442	glycosyl transferase family 8
TRESU_RS01115	COG0004	ammonium transporteR
TRESU_RS01130	COG1373	ATPase (AAA superfamily
TRESU_RS01140	COG3550	peptidyl-serine autophosphorylation
TRESU_RS01145	COG1396	sequence-specific DNA binding
TRESU_RS01155	COG2972	Histidine kinase
TRESU_RS01160	COG2207	Transcriptional regulator
TRESU_RS01160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TRESU_RS01165	COG4213	ABC transporter substrate-binding protein
TRESU_RS01170	COG0714	Associated with various cellular activities
TRESU_RS01205	COG0484	heat shock protein binding
TRESU_RS01210	COG0328	RNA-DNA hybrid ribonuclease activity
TRESU_RS01220	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TRESU_RS01240	COG0826	peptidase U32
TRESU_RS01320	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TRESU_RS01330	COG0019	diaminopimelate decarboxylase activity
TRESU_RS01340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TRESU_RS01465	COG0629	single-stranded DNA binding
TRESU_RS01490	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TRESU_RS01510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TRESU_RS01520	COG1477	protein flavinylation
TRESU_RS01525	COG0733	neurotransmitter:sodium symporter activity
TRESU_RS01625	COG0803	Belongs to the bacterial solute-binding protein 9 family
TRESU_RS01625	COG3443	Belongs to the bacterial solute-binding protein 9 family
TRESU_RS01630	COG1876	peptidase activity
TRESU_RS01635	COG1121	(ABC) transporter
TRESU_RS01720	COG0493	'glutamate synthase
TRESU_RS01725	COG0067	glutamate synthase
TRESU_RS01725	COG0070	glutamate synthase
TRESU_RS01725	COG0069	glutamate synthase activity
TRESU_RS01740	COG0205	6-phosphofructokinase activity
TRESU_RS01755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TRESU_RS01780	COG0442	prolyl-tRNA aminoacylation
TRESU_RS01785	COG1516	flagellar protein fliS
TRESU_RS01815	COG1739	Uncharacterized protein family UPF0029
TRESU_RS01830	COG0482	sulfurtransferase activity
TRESU_RS01870	COG0423	glycine-tRNA ligase activity
TRESU_RS01875	COG0656	L-ascorbic acid biosynthetic process
TRESU_RS01900	COG2604	Protein of unknown function DUF115
TRESU_RS01905	COG0768	penicillin binding
TRESU_RS01930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TRESU_RS01945	COG0440	acetolactate synthase activity
TRESU_RS01950	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TRESU_RS01975	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TRESU_RS01985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TRESU_RS01990	COG2197	response regulator
TRESU_RS01995	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TRESU_RS02015	COG0024	Methionine aminopeptidase
TRESU_RS02030	COG0154	amidase activity
TRESU_RS02035	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TRESU_RS02055	COG1472	Belongs to the glycosyl hydrolase 3 family
TRESU_RS02060	COG2207	Transcriptional regulator
TRESU_RS02065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TRESU_RS02065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TRESU_RS02065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
TRESU_RS02080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TRESU_RS02085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TRESU_RS02095	COG0105	UTP biosynthetic process
TRESU_RS02100	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TRESU_RS02105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TRESU_RS02135	COG0436	Aminotransferase
TRESU_RS02140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TRESU_RS02150	COG1523	belongs to the glycosyl hydrolase 13 family
TRESU_RS02205	COG5433	transposase activity
TRESU_RS02235	COG0326	Molecular chaperone. Has ATPase activity
TRESU_RS02240	COG2357	RelA SpoT domain protein
TRESU_RS02250	COG0165	Argininosuccinate lyase
TRESU_RS02255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TRESU_RS02260	COG0765	amino acid transport
TRESU_RS02275	COG1227	inorganic diphosphatase activity
TRESU_RS02275	COG0517	IMP dehydrogenase activity
TRESU_RS02315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TRESU_RS02315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TRESU_RS02315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TRESU_RS02330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TRESU_RS02335	COG4656	Part of a membrane complex involved in electron transport
TRESU_RS02340	COG4658	electron transport chain
TRESU_RS02350	COG4660	Part of a membrane complex involved in electron transport
TRESU_RS02355	COG4657	Part of a membrane complex involved in electron transport
TRESU_RS02365	COG1757	Na H antiporter
TRESU_RS02370	COG2233	PERMEase
TRESU_RS02375	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TRESU_RS02380	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TRESU_RS02385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TRESU_RS02390	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TRESU_RS02405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TRESU_RS02410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TRESU_RS02420	COG0587	DNA-directed DNA polymerase activity
TRESU_RS02430	COG2801	Transposase and inactivated derivatives
TRESU_RS02430	COG3415	Transposase
TRESU_RS02450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TRESU_RS02455	COG1181	Belongs to the D-alanine--D-alanine ligase family
TRESU_RS02460	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TRESU_RS02475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TRESU_RS02480	COG2116	formate transmembrane transporter activity
TRESU_RS02485	COG1640	4-alpha-glucanotransferase
TRESU_RS02495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TRESU_RS02505	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TRESU_RS02510	COG0107	imidazoleglycerol-phosphate synthase activity
TRESU_RS02520	COG0720	synthase
TRESU_RS02535	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TRESU_RS02555	COG1396	sequence-specific DNA binding
TRESU_RS02580	COG0811	peptide transport
TRESU_RS02585	COG0848	biopolymer transport protein
TRESU_RS02680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TRESU_RS02685	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
TRESU_RS02735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TRESU_RS02780	COG1373	ATPase (AAA superfamily
TRESU_RS02795	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TRESU_RS02815	COG1373	ATPase (AAA superfamily
TRESU_RS02835	COG1442	glycosyl transferase family 8
TRESU_RS02835	COG1216	Glycosyl transferase, family 2
TRESU_RS02840	COG0438	transferase activity, transferring glycosyl groups
TRESU_RS02845	COG0438	transferase activity, transferring glycosyl groups
TRESU_RS02850	COG0438	transferase activity, transferring glycosyl groups
TRESU_RS02930	COG1373	ATPase (AAA superfamily
TRESU_RS02945	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TRESU_RS02950	COG2239	Acts as a magnesium transporter
TRESU_RS03000	COG0732	type I restriction modification DNA specificity domain
TRESU_RS03025	COG0534	Mate efflux family protein
TRESU_RS03030	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TRESU_RS03045	COG1309	transcriptional regulator
TRESU_RS03060	COG0495	leucyl-tRNA aminoacylation
TRESU_RS03065	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TRESU_RS03085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TRESU_RS03095	COG0018	arginyl-trna synthetase
TRESU_RS03100	COG0372	Belongs to the citrate synthase family
TRESU_RS03105	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TRESU_RS03110	COG0443	Heat shock 70 kDa protein
TRESU_RS03115	COG0484	heat shock protein binding
TRESU_RS03135	COG1876	peptidase activity
TRESU_RS03160	COG3833	ABC-type maltose transport systems, permease component
TRESU_RS03165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TRESU_RS03170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TRESU_RS03175	COG0724	RNA recognition motif
TRESU_RS03185	COG0740	serine-type endopeptidase activity
TRESU_RS03190	COG3956	TIGRFAM MazG family protein
TRESU_RS03195	COG0193	aminoacyl-tRNA hydrolase activity
TRESU_RS03200	COG2207	Transcriptional regulator
TRESU_RS03210	COG0523	cobalamin synthesis protein
TRESU_RS03225	COG1074	ATP-dependent DNA helicase activity
TRESU_RS03245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
TRESU_RS03250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TRESU_RS03255	COG2816	NAD+ diphosphatase activity
TRESU_RS03270	COG3620	sequence-specific DNA binding
TRESU_RS03290	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS03405	COG2189	Belongs to the N(4) N(6)-methyltransferase family
TRESU_RS03415	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS03490	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
TRESU_RS03515	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS03570	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS03620	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS03745	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS03780	COG2337	Toxic component of a toxin-antitoxin (TA) module
TRESU_RS03785	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS03925	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS03960	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
TRESU_RS03980	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS04035	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS04055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TRESU_RS04065	COG0351	phosphomethylpyrimidine kinase
TRESU_RS04065	COG0352	thiamine-phosphate diphosphorylase activity
TRESU_RS04070	COG0352	thiamine-phosphate diphosphorylase activity
TRESU_RS04075	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
TRESU_RS04095	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
TRESU_RS04130	COG1472	Belongs to the glycosyl hydrolase 3 family
TRESU_RS04145	COG0445	tRNA wobble uridine modification
TRESU_RS04155	COG0006	proline dipeptidase activity
TRESU_RS04160	COG0728	peptidoglycan biosynthetic process
TRESU_RS04175	COG1187	pseudouridine synthase activity
TRESU_RS04180	COG2759	Belongs to the formate--tetrahydrofolate ligase family
TRESU_RS04190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TRESU_RS04195	COG0473	3-isopropylmalate dehydrogenase activity
TRESU_RS04200	COG2205	protein histidine kinase activity
TRESU_RS04200	COG2198	Histidine kinase
TRESU_RS04200	COG0784	Response regulator, receiver
TRESU_RS04210	COG2703	oxygen carrier activity
TRESU_RS04230	COG1115	amino acid carrier protein
TRESU_RS04255	COG0058	SHG alpha-glucan phosphorylase activity
TRESU_RS04270	COG0322	excinuclease ABC activity
TRESU_RS04285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TRESU_RS04290	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TRESU_RS04355	COG1079	Belongs to the binding-protein-dependent transport system permease family
TRESU_RS04360	COG4603	Belongs to the binding-protein-dependent transport system permease family
TRESU_RS04365	COG3845	ABC transporter
TRESU_RS04370	COG1744	ABC transporter substrate-binding protein PnrA-like
TRESU_RS04380	COG2801	Transposase and inactivated derivatives
TRESU_RS04380	COG3415	Transposase
TRESU_RS04435	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TRESU_RS04440	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TRESU_RS04445	COG1360	Flagellar Motor Protein
TRESU_RS04455	COG3630	sodium ion export across plasma membrane
TRESU_RS04480	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS04490	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TRESU_RS04505	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TRESU_RS04510	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TRESU_RS04525	COG0799	negative regulation of ribosome biogenesis
TRESU_RS04530	COG1388	LysM domain
TRESU_RS04530	COG0741	lytic transglycosylase activity
TRESU_RS04550	COG1862	Preprotein translocase
TRESU_RS04555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TRESU_RS04560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TRESU_RS04565	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TRESU_RS04590	COG0488	(ABC) transporter
TRESU_RS04595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TRESU_RS04600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TRESU_RS04655	COG5433	transposase activity
TRESU_RS04660	COG1222	aaa ATPase
TRESU_RS04685	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
TRESU_RS04695	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS04740	COG1528	Iron-storage protein
TRESU_RS04770	COG5433	transposase activity
TRESU_RS04825	COG0438	transferase activity, transferring glycosyl groups
TRESU_RS04885	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TRESU_RS04890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TRESU_RS04895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TRESU_RS04910	COG0137	argininosuccinate synthase activity
TRESU_RS04915	COG0149	triose-phosphate isomerase activity
TRESU_RS04920	COG2059	Chromate
TRESU_RS04935	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TRESU_RS04940	COG2890	protein-(glutamine-N5) methyltransferase activity
TRESU_RS04960	COG1121	(ABC) transporter
TRESU_RS04965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TRESU_RS04970	COG0546	phosphoglycolate phosphatase activity
TRESU_RS04975	COG1193	negative regulation of DNA recombination
TRESU_RS04980	COG1438	arginine binding
TRESU_RS04990	COG0166	Belongs to the GPI family
TRESU_RS04995	COG0084	hydrolase, TatD family'
TRESU_RS05010	COG0792	nuclease activity
TRESU_RS05025	COG0335	large ribosomal subunit rRNA binding
TRESU_RS05030	COG0336	Belongs to the RNA methyltransferase TrmD family
TRESU_RS05035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TRESU_RS05040	COG1837	Belongs to the UPF0109 family
TRESU_RS05055	COG1418	mRNA catabolic process
TRESU_RS05070	COG1696	Membrane protein involved in D-alanine export
TRESU_RS05080	COG0019	diaminopimelate decarboxylase activity
TRESU_RS05090	COG0463	Glycosyl transferase, family 2
TRESU_RS05090	COG1216	Glycosyl transferase, family 2
TRESU_RS05120	COG0463	Glycosyl transferase, family 2
TRESU_RS05160	COG2358	TRAP transporter, solute receptor (TAXI family
TRESU_RS05215	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TRESU_RS05220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TRESU_RS05280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TRESU_RS05285	COG0300	oxidoreductase activity
TRESU_RS05290	COG1472	Belongs to the glycosyl hydrolase 3 family
TRESU_RS05295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TRESU_RS05295	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
TRESU_RS05305	COG1671	Belongs to the UPF0178 family
TRESU_RS05310	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
TRESU_RS05320	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TRESU_RS05340	COG0191	fructose-bisphosphate aldolase activity
TRESU_RS05360	COG0632	four-way junction helicase activity
TRESU_RS05365	COG2255	four-way junction helicase activity
TRESU_RS05370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TRESU_RS05390	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TRESU_RS05395	COG1086	Polysaccharide biosynthesis protein
TRESU_RS05400	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TRESU_RS05430	COG0815	Transfers the fatty acyl group on membrane lipoproteins
TRESU_RS05435	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TRESU_RS05440	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TRESU_RS05445	COG3063	Type IV pilus biogenesis stability protein PilW
TRESU_RS05455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TRESU_RS05475	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TRESU_RS05480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TRESU_RS05485	COG0739	heme binding
TRESU_RS05490	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TRESU_RS05490	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
TRESU_RS05495	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
TRESU_RS05520	COG5433	transposase activity
TRESU_RS05640	COG4974	Belongs to the 'phage' integrase family
TRESU_RS05655	COG0732	type I restriction modification DNA specificity domain
TRESU_RS05660	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TRESU_RS05710	COG1766	The M ring may be actively involved in energy transduction
TRESU_RS05720	COG1317	bacterial-type flagellum organization
TRESU_RS05725	COG1157	protein secretion by the type III secretion system
TRESU_RS05740	COG1475	DNA binding
TRESU_RS05755	COG0307	riboflavin synthase, alpha
TRESU_RS05760	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TRESU_RS05760	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TRESU_RS05770	COG0124	histidyl-tRNA synthetase
TRESU_RS05775	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
TRESU_RS05780	COG2089	acid synthase
TRESU_RS05785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TRESU_RS05835	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TRESU_RS05845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TRESU_RS05850	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TRESU_RS05855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TRESU_RS05870	COG0736	holo-[acyl-carrier-protein] synthase activity
TRESU_RS05880	COG0101	tRNA pseudouridine synthase activity
TRESU_RS05900	COG0494	nUDIX hydrolase
TRESU_RS05920	COG1366	Belongs to the anti-sigma-factor antagonist family
TRESU_RS05955	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TRESU_RS05960	COG1722	exodeoxyribonuclease VII activity
TRESU_RS05965	COG1570	exodeoxyribonuclease VII activity
TRESU_RS05970	COG0731	radical SAM domain protein
TRESU_RS05980	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
TRESU_RS05985	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TRESU_RS05990	COG0860	N-Acetylmuramoyl-L-alanine amidase
TRESU_RS06020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TRESU_RS06030	COG2217	Heavy metal translocating P-type atpase
TRESU_RS06055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TRESU_RS06055	COG1773	rubredoxin
TRESU_RS06110	COG0488	(ABC) transporter
TRESU_RS06120	COG0750	zinc metalloprotease
TRESU_RS06125	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TRESU_RS06130	COG0575	Belongs to the CDS family
TRESU_RS06135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TRESU_RS06140	COG0233	cytoplasmic translational termination
TRESU_RS06145	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TRESU_RS06150	COG0052	Belongs to the universal ribosomal protein uS2 family
TRESU_RS06155	COG0424	maF-like protein
TRESU_RS06165	COG1413	lyase activity
TRESU_RS06175	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TRESU_RS06180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TRESU_RS06185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TRESU_RS06190	COG0571	ribonuclease III activity
TRESU_RS06220	COG0297	glycogen (starch) synthase activity
TRESU_RS06235	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TRESU_RS06245	COG0254	rRNA binding
TRESU_RS06295	COG0776	regulation of translation
TRESU_RS06300	COG0360	Binds together with S18 to 16S ribosomal RNA
TRESU_RS06305	COG0629	single-stranded DNA binding
TRESU_RS06310	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TRESU_RS06315	COG0359	binds to the 23S rRNA
TRESU_RS06320	COG0305	Participates in initiation and elongation during chromosome replication
TRESU_RS06335	COG0358	DNA primase activity
TRESU_RS06340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TRESU_RS06355	COG1077	Cell shape determining protein MreB Mrl
TRESU_RS06370	COG0768	penicillin binding
TRESU_RS06375	COG0772	Belongs to the SEDS family
TRESU_RS06405	COG1011	Hydrolase
TRESU_RS06410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TRESU_RS06415	COG0285	dihydrofolate synthase activity
TRESU_RS06430	COG1131	(ABC) transporter
TRESU_RS06435	COG1234	tRNA 3'-trailer cleavage
TRESU_RS06445	COG0662	Cupin 2, conserved barrel domain protein
TRESU_RS06445	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
TRESU_RS06450	COG1091	dTDP-4-dehydrorhamnose reductase activity
TRESU_RS06480	COG0564	pseudouridine synthase activity
TRESU_RS06500	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TRESU_RS06525	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TRESU_RS06530	COG1102	Psort location Cytoplasmic, score
TRESU_RS06545	COG2115	Belongs to the xylose isomerase family
TRESU_RS06550	COG1070	Carbohydrate kinase
TRESU_RS06555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TRESU_RS06555	COG2207	Transcriptional regulator
TRESU_RS06560	COG0484	heat shock protein binding
TRESU_RS06565	COG2204	response regulator
TRESU_RS06570	COG5002	protein histidine kinase activity
TRESU_RS06585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TRESU_RS06600	COG1122	ATPase activity
TRESU_RS06605	COG1122	ATPase activity
TRESU_RS06645	COG0544	peptidyl-prolyl cis-trans isomerase activity
TRESU_RS06650	COG0740	serine-type endopeptidase activity
TRESU_RS06655	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TRESU_RS06670	COG1196	nuclear chromosome segregation
TRESU_RS06680	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TRESU_RS06690	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TRESU_RS06695	COG0628	permease
TRESU_RS06710	COG0670	Belongs to the BI1 family
TRESU_RS06715	COG1199	ATP-dependent helicase activity
TRESU_RS06760	COG0543	2 iron, 2 sulfur cluster binding
TRESU_RS06770	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
TRESU_RS06780	COG1216	Glycosyl transferase, family 2
TRESU_RS06815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
TRESU_RS06815	COG0463	Glycosyl transferase, family 2
TRESU_RS06830	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
TRESU_RS06845	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TRESU_RS06845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TRESU_RS06850	COG2348	transferase activity, transferring amino-acyl groups
TRESU_RS06885	COG4656	Part of a membrane complex involved in electron transport
TRESU_RS06900	COG0564	pseudouridine synthase activity
TRESU_RS06910	COG0617	tRNA 3'-terminal CCA addition
TRESU_RS06915	COG2267	carboxylic ester hydrolase activity
TRESU_RS06920	COG0180	Tryptophanyl-tRNA synthetase
TRESU_RS06925	COG0297	glycogen (starch) synthase activity
TRESU_RS06930	COG0436	Aminotransferase
TRESU_RS06960	COG4211	Belongs to the binding-protein-dependent transport system permease family
TRESU_RS06965	COG1129	ABC transporter
TRESU_RS06970	COG1879	ABC-type sugar transport system periplasmic component
TRESU_RS06980	COG3459	Glycosyltransferase 36 associated
TRESU_RS06990	COG0742	ribosomal rna small subunit methyltransferase
TRESU_RS07015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TRESU_RS07020	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TRESU_RS07055	COG2252	PERMEase
TRESU_RS07065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TRESU_RS07070	COG1136	(ABC) transporter
TRESU_RS07080	COG3093	addiction module antidote protein HigA
TRESU_RS07145	COG0802	atpase or kinase
TRESU_RS07155	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
TRESU_RS07160	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
TRESU_RS07165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TRESU_RS07190	COG4786	Flagellar basal body rod
TRESU_RS07200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TRESU_RS07205	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TRESU_RS07220	COG0268	Binds directly to 16S ribosomal RNA
TRESU_RS07230	COG3867	Arabinogalactan endo-beta-1,4-galactanase
TRESU_RS07280	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TRESU_RS07290	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TRESU_RS07300	COG5433	transposase activity
TRESU_RS07305	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TRESU_RS07310	COG0706	membrane insertase activity
TRESU_RS07320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TRESU_RS07330	COG3118	belongs to the thioredoxin family
TRESU_RS07335	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TRESU_RS07345	COG1269	ATP hydrolysis coupled proton transport
TRESU_RS07350	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TRESU_RS07355	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TRESU_RS07365	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
TRESU_RS07400	COG0577	efflux transmembrane transporter activity
TRESU_RS07405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TRESU_RS07410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TRESU_RS07425	COG0232	Belongs to the dGTPase family. Type 2 subfamily
TRESU_RS07445	COG3867	Arabinogalactan endo-beta-1,4-galactanase
TRESU_RS07495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
TRESU_RS07515	COG0028	Belongs to the TPP enzyme family
TRESU_RS07520	COG3330	Domain of unknown function (DUF4912)
TRESU_RS07530	COG0706	membrane insertase activity
TRESU_RS07540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TRESU_RS07580	COG0542	response to heat
TRESU_RS07600	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TRESU_RS07605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TRESU_RS07610	COG1971	Probably functions as a manganese efflux pump
TRESU_RS07620	COG2502	aspartate--ammonia ligase
TRESU_RS07625	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
TRESU_RS07685	COG0563	adenylate kinase activity
TRESU_RS07690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TRESU_RS07715	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TRESU_RS07730	COG0396	ATPase activity
TRESU_RS07770	COG0765	amino acid transport
TRESU_RS07775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TRESU_RS07790	COG1469	GTP cyclohydrolase I activity
TRESU_RS07795	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TRESU_RS07810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TRESU_RS07815	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
TRESU_RS07820	COG1242	4 iron, 4 sulfur cluster binding
TRESU_RS07845	COG1191	sigma factor activity
TRESU_RS07860	COG1419	protein localization to endoplasmic reticulum
TRESU_RS07870	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TRESU_RS07875	COG1684	flagellar biosynthetic protein fliR
TRESU_RS07880	COG1987	bacterial-type flagellum assembly
TRESU_RS07885	COG1338	Plays a role in the flagellum-specific transport system
TRESU_RS07900	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TRESU_RS07905	COG1580	Controls the rotational direction of flagella during chemotaxis
TRESU_RS07910	COG1360	Flagellar Motor Protein
TRESU_RS07920	COG1582	Flagellar protein (FlbD)
TRESU_RS07925	COG1418	mRNA catabolic process
TRESU_RS07930	COG0745	RESPONSE REGULATOR receiver
TRESU_RS07935	COG5002	protein histidine kinase activity
TRESU_RS07940	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TRESU_RS07955	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
TRESU_RS08000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
TRESU_RS08010	COG0681	Belongs to the peptidase S26 family
TRESU_RS08025	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TRESU_RS08030	COG0534	Mate efflux family protein
TRESU_RS08060	COG0840	transmembrane signaling receptor activity
TRESU_RS08070	COG0301	tRNA thio-modification
TRESU_RS08085	COG0438	transferase activity, transferring glycosyl groups
TRESU_RS08090	COG1573	uracil-dna glycosylase
TRESU_RS08095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TRESU_RS08100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TRESU_RS08105	COG0653	protein targeting
TRESU_RS08110	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TRESU_RS08115	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TRESU_RS08120	COG4974	Belongs to the 'phage' integrase family
TRESU_RS08125	COG0551	DNA topoisomerase type I activity
TRESU_RS08125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TRESU_RS08130	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TRESU_RS08130	COG0758	DNA mediated transformation
TRESU_RS08140	COG4974	Belongs to the 'phage' integrase family
TRESU_RS08160	COG0772	Belongs to the SEDS family
TRESU_RS08165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TRESU_RS08175	COG0275	rRNA processing
TRESU_RS08180	COG2001	Belongs to the MraZ family
TRESU_RS08195	COG0217	transcriptional regulatory protein
TRESU_RS08205	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS08210	COG0564	pseudouridine synthase activity
TRESU_RS08220	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TRESU_RS08220	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TRESU_RS08220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TRESU_RS08240	COG2201	protein-glutamate methylesterase activity
TRESU_RS08250	COG0835	chemotaxis
TRESU_RS08255	COG0643	Histidine kinase
TRESU_RS08255	COG2198	Histidine kinase
TRESU_RS08265	COG0745	RESPONSE REGULATOR receiver
TRESU_RS08275	COG1394	ATPase activity, coupled to movement of substances
TRESU_RS08280	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TRESU_RS08285	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TRESU_RS08305	COG1269	ATP hydrolysis coupled proton transport
TRESU_RS08325	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TRESU_RS08365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TRESU_RS08425	COG2818	Glycosylase
TRESU_RS08460	COG0084	hydrolase, TatD family'
TRESU_RS08470	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TRESU_RS08475	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TRESU_RS08480	COG0126	phosphoglycerate kinase activity
TRESU_RS08495	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TRESU_RS08505	COG1702	phosphate starvation-inducible protein PhoH
TRESU_RS08515	COG0525	valine-tRNA ligase activity
TRESU_RS08545	COG1373	ATPase (AAA superfamily
TRESU_RS08550	COG4475	Protein of unknown function (DUF436)
TRESU_RS08555	COG1253	flavin adenine dinucleotide binding
TRESU_RS08605	COG2205	protein histidine kinase activity
TRESU_RS08610	COG0745	RESPONSE REGULATOR receiver
TRESU_RS08670	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
TRESU_RS08675	COG1691	(AIR) carboxylase
TRESU_RS08680	COG1606	tRNA processing
TRESU_RS08695	COG0840	transmembrane signaling receptor activity
TRESU_RS08700	COG5433	transposase activity
TRESU_RS08785	COG0629	single-stranded DNA binding
TRESU_RS08835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TRESU_RS08895	COG3451	type IV secretory pathway VirB4
TRESU_RS08910	COG4962	Type ii secretion system protein e
TRESU_RS09020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TRESU_RS09020	COG0551	DNA topoisomerase type I activity
TRESU_RS09030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TRESU_RS09115	COG3250	beta-galactosidase activity
TRESU_RS09130	COG0724	RNA recognition motif
TRESU_RS09145	COG0564	pseudouridine synthase activity
TRESU_RS09160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TRESU_RS09170	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TRESU_RS09170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TRESU_RS09175	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
TRESU_RS09185	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
TRESU_RS09190	COG2204	response regulator
TRESU_RS09195	COG0539	negative regulation of cytoplasmic translation
TRESU_RS09205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TRESU_RS09210	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
TRESU_RS09215	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TRESU_RS09220	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TRESU_RS09235	COG0739	heme binding
TRESU_RS09265	COG0481	GTPase activity
TRESU_RS09270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TRESU_RS09285	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TRESU_RS09300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TRESU_RS09325	COG0497	DNA recombination
TRESU_RS09330	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TRESU_RS09335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TRESU_RS09340	COG0835	chemotaxis
TRESU_RS09345	COG1040	competence protein
TRESU_RS09350	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TRESU_RS09360	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TRESU_RS09370	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TRESU_RS09385	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TRESU_RS09390	COG0646	methionine synthase
TRESU_RS09390	COG1410	methionine synthase
TRESU_RS09400	COG1482	cell wall glycoprotein biosynthetic process
TRESU_RS09415	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TRESU_RS09425	COG0501	Belongs to the peptidase M48B family
TRESU_RS09435	COG0287	Prephenate dehydrogenase
TRESU_RS09440	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TRESU_RS09450	COG2873	o-acetylhomoserine
TRESU_RS09455	COG0557	exoribonuclease II activity
TRESU_RS09470	COG0840	transmembrane signaling receptor activity
TRESU_RS09480	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TRESU_RS09485	COG1104	cysteine desulfurase activity
TRESU_RS09495	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TRESU_RS09505	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
TRESU_RS09525	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TRESU_RS09535	COG1747	RNA polymerase binding
TRESU_RS09535	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TRESU_RS09545	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TRESU_RS09550	COG0640	Transcriptional regulator
TRESU_RS09570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TRESU_RS09600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TRESU_RS09635	COG1051	belongs to the nudix hydrolase family
TRESU_RS09675	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TRESU_RS09695	COG4783	chaperone-mediated protein folding
TRESU_RS09835	COG0582	viral genome integration into host DNA
TRESU_RS09860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TRESU_RS09865	COG2226	methyltransferase
TRESU_RS09890	COG0583	DNA-binding transcription factor activity
TRESU_RS09910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TRESU_RS09920	COG0456	acetyltransferase
TRESU_RS09930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TRESU_RS09945	COG2264	protein methyltransferase activity
TRESU_RS09955	COG4585	Histidine kinase
TRESU_RS10070	COG3328	transposase activity
TRESU_RS10075	COG3177	Filamentation induced by cAMP protein fic
TRESU_RS10120	COG0583	DNA-binding transcription factor activity
TRESU_RS10130	COG5433	transposase activity
TRESU_RS10150	COG5433	transposase activity
TRESU_RS10170	COG4585	Histidine kinase
TRESU_RS10175	COG2197	response regulator
TRESU_RS10185	COG1373	ATPase (AAA superfamily
TRESU_RS10190	COG3040	lipid binding
TRESU_RS10195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TRESU_RS10195	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
TRESU_RS10220	COG3250	beta-galactosidase activity
TRESU_RS10245	COG1122	ATPase activity
TRESU_RS10270	COG0573	inorganic phosphate transmembrane transporter activity
TRESU_RS10275	COG0581	inorganic phosphate transmembrane transporter activity
TRESU_RS10280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TRESU_RS10285	COG0704	Plays a role in the regulation of phosphate uptake
TRESU_RS10300	COG4943	cyclic-guanylate-specific phosphodiesterase activity
TRESU_RS10310	COG5002	protein histidine kinase activity
TRESU_RS10315	COG2003	Belongs to the UPF0758 family
TRESU_RS10320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TRESU_RS10325	COG0556	nucleotide-excision repair
TRESU_RS10340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TRESU_RS10350	COG0321	lipoyl(octanoyl) transferase activity
TRESU_RS10350	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
TRESU_RS10360	COG0017	Asparaginyl-tRNA synthetase
TRESU_RS10390	COG2885	chlorophyll binding
TRESU_RS10405	COG2885	chlorophyll binding
TRESU_RS10410	COG0765	amino acid transport
TRESU_RS10415	COG4215	(ABC) transporter
TRESU_RS10420	COG1126	abc transporter atp-binding protein
TRESU_RS10445	COG0028	Belongs to the TPP enzyme family
TRESU_RS10455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TRESU_RS10465	COG1475	DNA binding
TRESU_RS10470	COG1192	Involved in chromosome partitioning
TRESU_RS10485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TRESU_RS10490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TRESU_RS10495	COG0534	Mate efflux family protein
TRESU_RS10500	COG3942	CHAP domain
TRESU_RS10500	COG1388	LysM domain
TRESU_RS10505	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
TRESU_RS10520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
TRESU_RS10535	COG1283	sodium-dependent phosphate transmembrane transporter activity
TRESU_RS10560	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TRESU_RS10580	COG0514	ATP-dependent DNA helicase (RecQ)
TRESU_RS10590	COG0343	queuine tRNA-ribosyltransferase activity
TRESU_RS10605	COG0756	dUTP diphosphatase activity
TRESU_RS10615	COG1185	polyribonucleotide nucleotidyltransferase activity
TRESU_RS10620	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TRESU_RS10635	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TRESU_RS10645	COG0779	Required for maturation of 30S ribosomal subunits
TRESU_RS10650	COG5433	transposase activity
TRESU_RS10665	COG0616	signal peptide processing
TRESU_RS10680	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TRESU_RS10690	COG1592	Rubrerythrin
TRESU_RS10700	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
TRESU_RS10705	COG3842	ATPase activity
TRESU_RS10710	COG1176	ABC-type spermidine putrescine transport system, permease component I
TRESU_RS10715	COG1177	transmembrane transport
TRESU_RS10725	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TRESU_RS10740	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
TRESU_RS10760	COG3977	Valine--pyruvate aminotransferase
TRESU_RS10765	COG0542	response to heat
TRESU_RS10770	COG3869	Catalyzes the specific phosphorylation of arginine residues in
TRESU_RS10775	COG3880	PFAM UvrB UvrC protein
TRESU_RS10785	COG1136	(ABC) transporter
TRESU_RS10800	COG0552	protein localization to endoplasmic reticulum
TRESU_RS10810	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TRESU_RS10825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TRESU_RS10845	COG0659	secondary active sulfate transmembrane transporter activity
TRESU_RS10850	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TRESU_RS10855	COG0012	GTP binding
TRESU_RS10860	COG0564	pseudouridine synthase activity
TRESU_RS10870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TRESU_RS10880	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TRESU_RS10885	COG0826	peptidase U32
TRESU_RS10895	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
TRESU_RS10905	COG2189	Belongs to the N(4) N(6)-methyltransferase family
TRESU_RS10935	COG0517	IMP dehydrogenase activity
TRESU_RS10935	COG0516	GMP reductase activity
TRESU_RS10940	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TRESU_RS10945	COG0534	Mate efflux family protein
TRESU_RS10955	COG1070	Carbohydrate kinase
TRESU_RS10960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TRESU_RS10975	COG0534	Mate efflux family protein
TRESU_RS10980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
TRESU_RS11000	COG0280	phosphate acetyltransferase
TRESU_RS11015	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
TRESU_RS11025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TRESU_RS11045	COG0488	(ABC) transporter
TRESU_RS11065	COG5433	transposase activity
TRESU_RS11075	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TRESU_RS11080	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TRESU_RS11130	COG1337	RAMP superfamily
TRESU_RS11165	COG3833	ABC-type maltose transport systems, permease component
TRESU_RS11170	COG1175	transmembrane transport
TRESU_RS11175	COG2182	Extracellular solute-binding protein
TRESU_RS11180	COG1609	Transcriptional regulator
TRESU_RS11185	COG0800	Aldolase
TRESU_RS11200	COG1966	Carbon starvation protein
TRESU_RS11210	COG0205	6-phosphofructokinase activity
TRESU_RS11215	COG1704	LemA family
TRESU_RS11225	COG2201	protein-glutamate methylesterase activity
TRESU_RS11235	COG0741	lytic transglycosylase activity
TRESU_RS11235	COG1196	nuclear chromosome segregation
TRESU_RS11235	COG0739	heme binding
TRESU_RS11240	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
TRESU_RS11245	COG1022	Amp-dependent synthetase and ligase
TRESU_RS11255	COG0789	Transcriptional regulator
TRESU_RS11285	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
TRESU_RS11285	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
TRESU_RS11300	COG1854	S-ribosylhomocysteine lyase activity
TRESU_RS11310	COG1362	aminopeptidase activity
TRESU_RS11320	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TRESU_RS11320	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TRESU_RS11455	COG4585	Histidine kinase
TRESU_RS11520	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
TRESU_RS11525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TRESU_RS11530	COG1937	Protein conserved in bacteria
TRESU_RS11540	COG2217	Heavy metal translocating P-type atpase
TRESU_RS11550	COG0514	ATP-dependent DNA helicase (RecQ)
TRESU_RS11555	COG0475	glutathione-regulated potassium exporter activity
TRESU_RS11570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TRESU_RS11610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TRESU_RS11615	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TRESU_RS11620	COG0215	cysteine-tRNA ligase activity
TRESU_RS11640	COG0528	UMP kinase activity
TRESU_RS11650	COG0151	Belongs to the GarS family
TRESU_RS11655	COG1968	undecaprenyl-diphosphatase activity
TRESU_RS11660	COG0569	domain protein
TRESU_RS11665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TRESU_RS11675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TRESU_RS11685	COG0330	HflC and HflK could
TRESU_RS11690	COG0330	HflC and HflK could
TRESU_RS11705	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TRESU_RS11725	COG1774	PSP1 C-terminal conserved region
TRESU_RS11740	COG0739	heme binding
TRESU_RS11745	COG0084	hydrolase, TatD family'
TRESU_RS11750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TRESU_RS11750	COG3116	cell division
TRESU_RS11760	COG4251	negative regulation of phosphorylation
TRESU_RS11760	COG5001	Diguanylate cyclase
TRESU_RS11760	COG2203	Gaf domain
TRESU_RS11760	COG3706	GGDEF domain
TRESU_RS11790	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TRESU_RS11815	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TRESU_RS11830	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS11840	COG1598	PFAM Uncharacterised protein family UPF0150
TRESU_RS11855	COG1373	ATPase (AAA superfamily
TRESU_RS11865	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TRESU_RS11870	COG2900	Belongs to the SlyX family
TRESU_RS11875	COG1272	protein, Hemolysin III
TRESU_RS11880	COG1172	Belongs to the binding-protein-dependent transport system permease family
TRESU_RS11895	COG0148	phosphopyruvate hydratase activity
TRESU_RS11920	COG1122	ATPase activity
TRESU_RS11975	COG1879	ABC-type sugar transport system periplasmic component
TRESU_RS11985	COG1172	Belongs to the binding-protein-dependent transport system permease family
TRESU_RS11990	COG1172	Belongs to the binding-protein-dependent transport system permease family
TRESU_RS11995	COG2207	Transcriptional regulator
TRESU_RS12010	COG2169	Transcriptional regulator
TRESU_RS12015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TRESU_RS12020	COG0668	transmembrane transport
TRESU_RS12035	COG4166	transmembrane transport
TRESU_RS12075	COG4443	Transcriptional Coactivator p15 (PC4)
TRESU_RS12085	COG1652	LysM domain
TRESU_RS12090	COG0494	nUDIX hydrolase
TRESU_RS12100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TRESU_RS12115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TRESU_RS12120	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TRESU_RS12135	COG0667	Aldo Keto reductase
TRESU_RS12150	COG1119	ATPase activity
TRESU_RS12165	COG5433	transposase activity
TRESU_RS12195	COG1137	ATPase activity
TRESU_RS12220	COG5433	transposase activity
TRESU_RS12225	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TRESU_RS12250	COG3012	SEC-C Motif Domain Protein
TRESU_RS12285	COG0475	glutathione-regulated potassium exporter activity
TRESU_RS12305	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TRESU_RS12335	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TRESU_RS12340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TRESU_RS12345	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TRESU_RS12355	COG2201	protein-glutamate methylesterase activity
TRESU_RS12385	COG0517	IMP dehydrogenase activity
TRESU_RS12385	COG0516	GMP reductase activity
TRESU_RS12395	COG0411	ABC transporter
TRESU_RS12410	COG0683	leucine binding
TRESU_RS12420	COG0203	ribosomal protein L17
TRESU_RS12425	COG0202	RNA polymerase activity
TRESU_RS12430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TRESU_RS12435	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TRESU_RS12445	COG0200	Binds to the 23S rRNA
TRESU_RS12455	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TRESU_RS12460	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TRESU_RS12470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TRESU_RS12475	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TRESU_RS12480	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TRESU_RS12485	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TRESU_RS12490	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TRESU_RS12495	COG0255	Belongs to the universal ribosomal protein uL29 family
TRESU_RS12505	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TRESU_RS12510	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TRESU_RS12520	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TRESU_RS12525	COG0089	rRNA binding
TRESU_RS12530	COG0088	Forms part of the polypeptide exit tunnel
TRESU_RS12535	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TRESU_RS12540	COG0051	transcription antitermination factor activity, RNA binding
TRESU_RS12545	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TRESU_RS12550	COG0049	tRNA binding
TRESU_RS12555	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
TRESU_RS12560	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TRESU_RS12565	COG0085	RNA polymerase activity
TRESU_RS12570	COG0222	ribosome binding
TRESU_RS12575	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TRESU_RS12580	COG0081	regulation of translation
TRESU_RS12585	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TRESU_RS12590	COG0250	Participates in transcription elongation, termination and antitermination
TRESU_RS12595	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TRESU_RS12605	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TRESU_RS12615	COG1045	serine acetyltransferase
TRESU_RS12665	COG0455	bacterial-type flagellum organization
TRESU_RS12670	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TRESU_RS12675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TRESU_RS12680	COG0138	bifunctional purine biosynthesis protein purh
TRESU_RS12685	COG0140	phosphoribosyl-ATP diphosphatase activity
TRESU_RS12685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TRESU_RS12695	COG5001	Diguanylate cyclase
TRESU_RS12695	COG3300	MHYT domain
TRESU_RS12720	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TRESU_RS12765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TRESU_RS12775	COG4120	Belongs to the binding-protein-dependent transport system permease family
TRESU_RS12780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TRESU_RS12790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TRESU_RS12810	COG0564	pseudouridine synthase activity
TRESU_RS12820	COG1053	succinate dehydrogenase
TRESU_RS12850	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TRESU_RS12855	COG0622	Phosphoesterase
TRESU_RS12875	COG1454	alcohol dehydrogenase
TRESU_RS12885	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TRESU_RS12890	COG1674	ftsk spoiiie
TRESU_RS12895	COG3858	chitin binding
TRESU_RS12905	COG1464	Belongs to the NlpA lipoprotein family
TRESU_RS12915	COG0436	Aminotransferase
TRESU_RS12920	COG1522	sequence-specific DNA binding
TRESU_RS12925	COG0131	Imidazoleglycerol-phosphate dehydratase
TRESU_RS12930	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TRESU_RS12935	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TRESU_RS12940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TRESU_RS12950	COG1061	Type III restriction enzyme res subunit
TRESU_RS12955	COG1592	Rubrerythrin
TRESU_RS12955	COG1773	rubredoxin
TRESU_RS12975	COG0116	Belongs to the methyltransferase superfamily
TRESU_RS12980	COG5433	transposase activity
TRESU_RS13025	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
TRESU_RS13045	COG1396	sequence-specific DNA binding
TRESU_RS13060	COG0539	negative regulation of cytoplasmic translation
TRESU_RS13065	COG1051	belongs to the nudix hydrolase family
TRESU_RS13080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TRESU_RS13085	COG0187	DNA topoisomerase II activity
TRESU_RS13110	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TRESU_RS13275	COG2885	chlorophyll binding
TRESU_RS13415	COG3507	Belongs to the glycosyl hydrolase 43 family
TRESU_RS13470	COG3409	Peptidoglycan-binding domain 1 protein
TRESU_RS13470	COG0793	Belongs to the peptidase S41A family
TRESU_RS13955	COG4191	Histidine kinase
TRESU_RS13955	COG0745	RESPONSE REGULATOR receiver
TRESU_RS13955	COG2205	protein histidine kinase activity
TRESU_RS13960	COG0571	ribonuclease III activity
TRESU_RS14005	COG0739	heme binding
TRESU_RS14015	COG1686	Belongs to the peptidase S11 family
TRESU_RS14035	COG0840	transmembrane signaling receptor activity
TRESU_RS14040	COG1401	restriction endodeoxyribonuclease activity
TRESU_RS14050	COG3475	LICD family
TRESU_RS14075	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS14125	COG3547	Transposase (IS116 IS110 IS902 family)
TRESU_RS14150	COG3290	protein histidine kinase activity
TRESU_RS14150	COG0840	transmembrane signaling receptor activity
TRESU_RS14155	COG2868	ribosomal protein
TRESU_RS14160	COG0784	Response regulator, receiver
TRESU_RS14160	COG2205	protein histidine kinase activity
TRESU_RS14165	COG0745	RESPONSE REGULATOR receiver
TRESU_RS14180	COG4122	O-methyltransferase activity
TRESU_RS14230	COG0666	response to abiotic stimulus
TRESU_RS14235	COG3475	LICD family
TRESU_RS14305	COG0037	tRNA processing
TRESU_RS14315	COG5433	transposase activity
TRESU_RS14320	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
TRESU_RS14325	COG5433	transposase activity
TRESU_RS14330	COG5433	transposase activity
TRESU_RS14360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TRESU_RS14365	COG3437	response regulator, receiver
TRESU_RS14400	COG0840	transmembrane signaling receptor activity
TRESU_RS14425	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TRESU_RS14440	COG2199	diguanylate cyclase activity
TRESU_RS14440	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TRESU_RS14445	COG0167	dihydroorotate dehydrogenase activity