TW_RS00830 144c527b13d8475c29f58d21dca291f5 154 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 24 154 32.37 T 11-11-2016 IPR023035 Ribosomal protein S9, bacterial/plastid TW_RS00830 144c527b13d8475c29f58d21dca291f5 154 Pfam PF00380 Ribosomal protein S9/S16 33 154 3.5E-44 T 11-11-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TW_RS00830 144c527b13d8475c29f58d21dca291f5 154 SUPERFAMILY SSF54211 31 154 6.07E-44 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS00830 144c527b13d8475c29f58d21dca291f5 154 ProSitePatterns PS00360 Ribosomal protein S9 signature. 92 110 - T 11-11-2016 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 TW_RS00830 144c527b13d8475c29f58d21dca291f5 154 Gene3D G3DSA:3.30.230.10 30 154 1.9E-47 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TW_RS02335 edc87f3469d0da73d3b3bb465e11852c 92 SUPERFAMILY SSF117916 1 86 1.67E-23 T 11-11-2016 TW_RS02335 edc87f3469d0da73d3b3bb465e11852c 92 Pfam PF01883 Domain of unknown function DUF59 1 57 2.3E-16 T 11-11-2016 IPR002744 Domain of unknown function DUF59 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 312 33.462 T 11-11-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 Gene3D G3DSA:1.10.150.20 243 317 1.5E-29 T 11-11-2016 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 Gene3D G3DSA:2.170.120.12 62 169 1.2E-40 T 11-11-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 SUPERFAMILY SSF56553 48 170 1.16E-39 T 11-11-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 150 3.4E-21 T 11-11-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 1.1E-106 T 11-11-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 SMART SM00662 18 226 9.0E-73 T 11-11-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 SUPERFAMILY SSF47789 248 319 1.09E-23 T 11-11-2016 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 Gene3D G3DSA:3.30.1360.10 9 61 2.3E-10 T 11-11-2016 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 244 304 8.6E-26 T 11-11-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 SUPERFAMILY SSF55257 13 48 1.81E-23 T 11-11-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 SUPERFAMILY SSF55257 171 221 1.81E-23 T 11-11-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 251 317 4.0E-32 T 11-11-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS01265 b8bc260f8616b093c356b24f36d9e17a 327 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 1.8E-18 T 11-11-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS03480 1b072a6b8b0953ca543b7b3369dfa502 247 Pfam PF03725 3' exoribonuclease family, domain 2 168 233 2.6E-13 T 11-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TW_RS03480 1b072a6b8b0953ca543b7b3369dfa502 247 ProSitePatterns PS01277 Ribonuclease PH signature. 126 139 - T 11-11-2016 IPR018336 Ribonuclease PH, conserved site TW_RS03480 1b072a6b8b0953ca543b7b3369dfa502 247 SUPERFAMILY SSF54211 11 191 8.6E-40 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS03480 1b072a6b8b0953ca543b7b3369dfa502 247 Gene3D G3DSA:3.30.230.70 9 243 1.7E-28 T 11-11-2016 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TW_RS03480 1b072a6b8b0953ca543b7b3369dfa502 247 SUPERFAMILY SSF55666 161 244 5.89E-23 T 11-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TW_RS03480 1b072a6b8b0953ca543b7b3369dfa502 247 Pfam PF01138 3' exoribonuclease family, domain 1 20 150 2.0E-18 T 11-11-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TW_RS03480 1b072a6b8b0953ca543b7b3369dfa502 247 Hamap MF_00564 Ribonuclease PH [rph]. 11 247 43.151 T 11-11-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 TW_RS03480 1b072a6b8b0953ca543b7b3369dfa502 247 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 12 246 4.6E-102 T 11-11-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 TW_RS01280 a27f56a6ae15acd9852dda20ec137d47 371 Pfam PF01883 Domain of unknown function DUF59 6 68 3.6E-13 T 11-11-2016 IPR002744 Domain of unknown function DUF59 TW_RS01280 a27f56a6ae15acd9852dda20ec137d47 371 Hamap MF_02040 Iron-sulfur cluster carrier protein. 98 370 30.726 T 11-11-2016 IPR019591 Mrp/NBP35 ATP-binding protein TW_RS01280 a27f56a6ae15acd9852dda20ec137d47 371 SUPERFAMILY SSF52540 104 366 4.83E-41 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01280 a27f56a6ae15acd9852dda20ec137d47 371 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 105 365 3.2E-70 T 11-11-2016 IPR019591 Mrp/NBP35 ATP-binding protein TW_RS01280 a27f56a6ae15acd9852dda20ec137d47 371 Gene3D G3DSA:3.40.50.300 102 364 3.9E-73 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01280 a27f56a6ae15acd9852dda20ec137d47 371 SUPERFAMILY SSF117916 2 93 1.34E-17 T 11-11-2016 TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 SMART SM00382 348 517 1.3E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 SMART SM00382 30 251 6.3E-12 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 Pfam PF12848 ABC transporter 230 296 6.3E-11 T 11-11-2016 IPR032781 ABC-transporter extension domain TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 552 4.0E-255 T 11-11-2016 IPR022374 ABC transporter, ATP-binding protein, ChvD TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 Gene3D G3DSA:3.40.50.300 340 512 8.2E-38 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 Gene3D G3DSA:3.40.50.300 12 92 2.0E-50 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 Gene3D G3DSA:3.40.50.300 127 275 2.0E-50 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 SUPERFAMILY SSF52540 13 242 2.31E-48 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 SUPERFAMILY SSF52540 307 513 2.09E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 Pfam PF00005 ABC transporter 21 190 1.5E-26 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS01960 205f4eb1ef1796e850672cd185fb7131 556 Pfam PF00005 ABC transporter 340 473 2.6E-17 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS00980 af79a4958af9642c8c5353f0858f9bcb 668 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 200 331 3.0E-45 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TW_RS00980 af79a4958af9642c8c5353f0858f9bcb 668 SUPERFAMILY SSF52540 155 404 2.93E-71 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00980 af79a4958af9642c8c5353f0858f9bcb 668 Gene3D G3DSA:1.10.8.60 342 407 7.3E-24 T 11-11-2016 TW_RS00980 af79a4958af9642c8c5353f0858f9bcb 668 Pfam PF01434 Peptidase family M41 395 602 2.4E-75 T 11-11-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 TW_RS00980 af79a4958af9642c8c5353f0858f9bcb 668 ProSitePatterns PS00674 AAA-protein family signature. 303 321 - T 11-11-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TW_RS00980 af79a4958af9642c8c5353f0858f9bcb 668 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 115 603 2.7E-218 T 11-11-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 TW_RS00980 af79a4958af9642c8c5353f0858f9bcb 668 Gene3D G3DSA:3.40.50.300 156 341 3.5E-63 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00980 af79a4958af9642c8c5353f0858f9bcb 668 SMART SM00382 196 335 9.8E-25 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00980 af79a4958af9642c8c5353f0858f9bcb 668 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 612 35.954 T 11-11-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 TW_RS00980 af79a4958af9642c8c5353f0858f9bcb 668 SUPERFAMILY SSF140990 414 612 9.68E-67 T 11-11-2016 TW_RS03010 f18ae0723455b08e2c711e20f5580f62 567 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 14 567 44.11 T 11-11-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TW_RS03010 f18ae0723455b08e2c711e20f5580f62 567 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 478 489 - T 11-11-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TW_RS03010 f18ae0723455b08e2c711e20f5580f62 567 Pfam PF00920 Dehydratase family 44 565 2.6E-207 T 11-11-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TW_RS03010 f18ae0723455b08e2c711e20f5580f62 567 SUPERFAMILY SSF143975 10 391 2.62E-131 T 11-11-2016 TW_RS03010 f18ae0723455b08e2c711e20f5580f62 567 SUPERFAMILY SSF52016 392 566 2.2E-53 T 11-11-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel TW_RS03010 f18ae0723455b08e2c711e20f5580f62 567 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 132 142 - T 11-11-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TW_RS03010 f18ae0723455b08e2c711e20f5580f62 567 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 28 566 7.8E-213 T 11-11-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 4 404 2.7E-172 T 11-11-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 5 415 47.249 T 11-11-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 Gene3D G3DSA:3.40.50.300 70 259 2.6E-48 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 Gene3D G3DSA:3.40.50.300 294 311 2.6E-48 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 2.5E-14 T 11-11-2016 IPR019489 Clp ATPase, C-terminal TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 SMART SM01086 317 412 1.2E-28 T 11-11-2016 IPR019489 Clp ATPase, C-terminal TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 Pfam PF06689 ClpX C4-type zinc finger 8 44 4.1E-14 T 11-11-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 Gene3D G3DSA:1.10.8.60 317 419 1.1E-32 T 11-11-2016 TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 SMART SM00382 117 274 5.5E-10 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 SUPERFAMILY SSF57716 7 42 1.71E-9 T 11-11-2016 TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 SUPERFAMILY SSF52540 68 403 1.3E-62 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 Pfam PF07724 AAA domain (Cdc48 subfamily) 118 311 6.8E-48 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TW_RS01535 734dfd43e73573675a1540f39ea9c548 423 SMART SM00994 6 45 6.3E-16 T 11-11-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TW_RS02700 87b15a078d426054be61d26f97297acf 640 SUPERFAMILY SSF52954 520 624 2.87E-22 T 11-11-2016 IPR004154 Anticodon-binding TW_RS02700 87b15a078d426054be61d26f97297acf 640 Gene3D G3DSA:3.30.54.20 109 167 1.8E-14 T 11-11-2016 TW_RS02700 87b15a078d426054be61d26f97297acf 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 44 625 30.609 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TW_RS02700 87b15a078d426054be61d26f97297acf 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 157 200 1.6E-11 T 11-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 TW_RS02700 87b15a078d426054be61d26f97297acf 640 Gene3D G3DSA:3.30.930.10 224 521 2.8E-95 T 11-11-2016 TW_RS02700 87b15a078d426054be61d26f97297acf 640 SUPERFAMILY SSF55681 224 516 2.81E-82 T 11-11-2016 TW_RS02700 87b15a078d426054be61d26f97297acf 640 Gene3D G3DSA:3.30.980.10 168 204 2.5E-35 T 11-11-2016 TW_RS02700 87b15a078d426054be61d26f97297acf 640 Gene3D G3DSA:3.30.980.10 44 107 2.5E-35 T 11-11-2016 TW_RS02700 87b15a078d426054be61d26f97297acf 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 455 483 1.5E-51 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TW_RS02700 87b15a078d426054be61d26f97297acf 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 525 537 1.5E-51 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TW_RS02700 87b15a078d426054be61d26f97297acf 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 351 374 1.5E-51 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TW_RS02700 87b15a078d426054be61d26f97297acf 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 318 346 1.5E-51 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TW_RS02700 87b15a078d426054be61d26f97297acf 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 498 511 1.5E-51 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TW_RS02700 87b15a078d426054be61d26f97297acf 640 SMART SM00863 143 200 1.9E-18 T 11-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 TW_RS02700 87b15a078d426054be61d26f97297acf 640 Gene3D G3DSA:3.40.50.800 522 626 1.7E-22 T 11-11-2016 IPR004154 Anticodon-binding TW_RS02700 87b15a078d426054be61d26f97297acf 640 SUPERFAMILY SSF55186 41 220 2.35E-52 T 11-11-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 TW_RS02700 87b15a078d426054be61d26f97297acf 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 50 617 6.7E-181 T 11-11-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TW_RS02700 87b15a078d426054be61d26f97297acf 640 Pfam PF03129 Anticodon binding domain 532 616 5.5E-12 T 11-11-2016 IPR004154 Anticodon-binding TW_RS02700 87b15a078d426054be61d26f97297acf 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 315 520 6.4E-36 T 11-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS00145 4a1f33f2354577b9c552d76bac028c59 417 SUPERFAMILY SSF52440 25 117 7.91E-19 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS00145 4a1f33f2354577b9c552d76bac028c59 417 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 25 397 33.605 T 11-11-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TW_RS00145 4a1f33f2354577b9c552d76bac028c59 417 SUPERFAMILY SSF51246 346 412 6.83E-13 T 11-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS00145 4a1f33f2354577b9c552d76bac028c59 417 Gene3D G3DSA:3.40.50.20 25 128 2.7E-25 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS00145 4a1f33f2354577b9c552d76bac028c59 417 Pfam PF02222 ATP-grasp domain 130 233 1.7E-18 T 11-11-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TW_RS00145 4a1f33f2354577b9c552d76bac028c59 417 Pfam PF02222 ATP-grasp domain 263 320 5.0E-20 T 11-11-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TW_RS00145 4a1f33f2354577b9c552d76bac028c59 417 SUPERFAMILY SSF56059 120 233 3.01E-45 T 11-11-2016 TW_RS00145 4a1f33f2354577b9c552d76bac028c59 417 SUPERFAMILY SSF56059 263 341 3.01E-45 T 11-11-2016 TW_RS00145 4a1f33f2354577b9c552d76bac028c59 417 Gene3D G3DSA:3.30.1490.20 136 170 9.6E-9 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TW_RS00145 4a1f33f2354577b9c552d76bac028c59 417 Gene3D G3DSA:3.30.470.20 171 413 2.3E-76 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 SUPERFAMILY SSF89000 829 995 2.79E-36 T 11-11-2016 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 Pfam PF00364 Biotin-requiring enzyme 1072 1129 7.5E-15 T 11-11-2016 IPR000089 Biotin/lipoyl attachment TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 Pfam PF02436 Conserved carboxylase domain 824 1007 1.9E-47 T 11-11-2016 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 SMART SM00878 339 446 2.0E-47 T 11-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 111 6.6E-38 T 11-11-2016 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 Pfam PF02785 Biotin carboxylase C-terminal domain 339 446 5.8E-33 T 11-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 Gene3D G3DSA:3.30.470.20 203 448 2.3E-94 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 PIRSF PIRSF001594 1 1131 0.0 T 11-11-2016 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 Gene3D G3DSA:2.40.50.100 1055 1130 2.2E-20 T 11-11-2016 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 Pfam PF00682 HMGL-like 530 799 7.0E-23 T 11-11-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 Gene3D G3DSA:3.40.50.20 2 130 8.2E-44 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 Gene3D G3DSA:3.30.1490.20 131 200 5.1E-21 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 Gene3D G3DSA:3.10.600.10 964 1051 7.1E-22 T 11-11-2016 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1086 1103 - T 11-11-2016 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 SUPERFAMILY SSF56059 84 352 7.6E-63 T 11-11-2016 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 Gene3D G3DSA:3.20.20.70 507 815 7.4E-127 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 SUPERFAMILY SSF51246 334 448 5.23E-35 T 11-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 SUPERFAMILY SSF51230 1054 1129 7.85E-17 T 11-11-2016 IPR011053 Single hybrid motif TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 SUPERFAMILY SSF51569 521 832 2.38E-75 T 11-11-2016 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1129 0.0 T 11-11-2016 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 SUPERFAMILY SSF52440 2 111 6.12E-38 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 1.9E-71 T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TW_RS03540 1ddb1c5ff35025a206dd74fa784aded5 1131 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TW_RS00415 9a7bc3222fda707e8e9cbfcd54843f8e 453 SUPERFAMILY SSF53474 259 452 3.38E-27 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold TW_RS00415 9a7bc3222fda707e8e9cbfcd54843f8e 453 Pfam PF02230 Phospholipase/Carboxylesterase 23 235 7.9E-13 T 11-11-2016 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 TW_RS00415 9a7bc3222fda707e8e9cbfcd54843f8e 453 Pfam PF02230 Phospholipase/Carboxylesterase 260 452 1.6E-12 T 11-11-2016 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 TW_RS00415 9a7bc3222fda707e8e9cbfcd54843f8e 453 SUPERFAMILY SSF53474 20 238 5.5E-26 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold TW_RS00415 9a7bc3222fda707e8e9cbfcd54843f8e 453 Gene3D G3DSA:3.40.50.1820 13 237 1.6E-45 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold TW_RS00415 9a7bc3222fda707e8e9cbfcd54843f8e 453 Gene3D G3DSA:3.40.50.1820 238 453 6.5E-52 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold TW_RS02800 3cbe4f6c23596f1c420b07849745ec81 283 PRINTS PR01166 Cytochrome c oxidase subunit II signature 129 148 1.2E-8 T 11-11-2016 TW_RS02800 3cbe4f6c23596f1c420b07849745ec81 283 PRINTS PR01166 Cytochrome c oxidase subunit II signature 194 214 1.2E-8 T 11-11-2016 TW_RS02800 3cbe4f6c23596f1c420b07849745ec81 283 PRINTS PR01166 Cytochrome c oxidase subunit II signature 232 249 1.2E-8 T 11-11-2016 TW_RS02800 3cbe4f6c23596f1c420b07849745ec81 283 PRINTS PR01166 Cytochrome c oxidase subunit II signature 214 231 1.2E-8 T 11-11-2016 TW_RS02800 3cbe4f6c23596f1c420b07849745ec81 283 SUPERFAMILY SSF49503 132 262 1.36E-38 T 11-11-2016 IPR008972 Cupredoxin TW_RS02800 3cbe4f6c23596f1c420b07849745ec81 283 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 195 243 - T 11-11-2016 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02800 3cbe4f6c23596f1c420b07849745ec81 283 SUPERFAMILY SSF81464 43 121 5.4E-14 T 11-11-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02800 3cbe4f6c23596f1c420b07849745ec81 283 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 135 250 4.1E-17 T 11-11-2016 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02800 3cbe4f6c23596f1c420b07849745ec81 283 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 48 259 3.7E-46 T 11-11-2016 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02800 3cbe4f6c23596f1c420b07849745ec81 283 Gene3D G3DSA:1.10.287.90 43 122 5.0E-13 T 11-11-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02800 3cbe4f6c23596f1c420b07849745ec81 283 Gene3D G3DSA:2.60.40.420 132 261 1.7E-36 T 11-11-2016 IPR008972 Cupredoxin TW_RS02685 a9951a2b28c79423b57f44799e32ff20 188 PIRSF PIRSF005639 1 188 4.4E-68 T 11-11-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TW_RS02685 a9951a2b28c79423b57f44799e32ff20 188 SUPERFAMILY SSF52317 2 185 5.59E-47 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS02685 a9951a2b28c79423b57f44799e32ff20 188 Pfam PF01174 SNO glutamine amidotransferase family 5 183 3.5E-53 T 11-11-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TW_RS02685 a9951a2b28c79423b57f44799e32ff20 188 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 183 1.5E-62 T 11-11-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TW_RS02685 a9951a2b28c79423b57f44799e32ff20 188 ProSitePatterns PS01236 PdxT/SNO family family signature. 40 50 - T 11-11-2016 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TW_RS02685 a9951a2b28c79423b57f44799e32ff20 188 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 185 35.012 T 11-11-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TW_RS02685 a9951a2b28c79423b57f44799e32ff20 188 Gene3D G3DSA:3.40.50.880 1 184 8.2E-66 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS00550 860ddb6a2c41c1fc1d24116d0a611704 349 Gene3D G3DSA:1.10.150.130 20 113 1.0E-16 T 11-11-2016 IPR023109 Integrase/recombinase, N-terminal TW_RS00550 860ddb6a2c41c1fc1d24116d0a611704 349 Gene3D G3DSA:1.10.443.10 259 341 2.6E-52 T 11-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TW_RS00550 860ddb6a2c41c1fc1d24116d0a611704 349 Gene3D G3DSA:1.10.443.10 126 224 2.6E-52 T 11-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TW_RS00550 860ddb6a2c41c1fc1d24116d0a611704 349 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 30 104 6.2E-11 T 11-11-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TW_RS00550 860ddb6a2c41c1fc1d24116d0a611704 349 Pfam PF00589 Phage integrase family 129 333 2.5E-42 T 11-11-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TW_RS00550 860ddb6a2c41c1fc1d24116d0a611704 349 SUPERFAMILY SSF56349 30 218 5.3E-51 T 11-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TW_RS00550 860ddb6a2c41c1fc1d24116d0a611704 349 SUPERFAMILY SSF56349 254 340 5.3E-51 T 11-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TW_RS00550 860ddb6a2c41c1fc1d24116d0a611704 349 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 20 348 51.529 T 11-11-2016 IPR023009 Tyrosine recombinase XerC/XerD TW_RS00635 52637ebcf774a9f9d1f3faa5459826be 305 Pfam PF00378 Enoyl-CoA hydratase/isomerase 44 299 1.0E-55 T 11-11-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 TW_RS00635 52637ebcf774a9f9d1f3faa5459826be 305 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 142 162 - T 11-11-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 TW_RS00635 52637ebcf774a9f9d1f3faa5459826be 305 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 27 304 49.437 T 11-11-2016 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 TW_RS00635 52637ebcf774a9f9d1f3faa5459826be 305 Gene3D G3DSA:1.10.12.10 243 293 1.5E-26 T 11-11-2016 IPR014748 Crontonase, C-terminal TW_RS00635 52637ebcf774a9f9d1f3faa5459826be 305 SUPERFAMILY SSF52096 36 302 5.55E-73 T 11-11-2016 IPR029045 ClpP/crotonase-like domain TW_RS00635 52637ebcf774a9f9d1f3faa5459826be 305 Gene3D G3DSA:3.90.226.10 37 241 4.9E-61 T 11-11-2016 IPR029045 ClpP/crotonase-like domain TW_RS00635 52637ebcf774a9f9d1f3faa5459826be 305 TIGRFAM TIGR01929 menB: naphthoate synthase 37 301 3.1E-113 T 11-11-2016 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 TW_RS00755 02e310db423db165f6e74fe485b86caf 968 SUPERFAMILY SSF53383 493 903 5.18E-87 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase TW_RS00755 02e310db423db165f6e74fe485b86caf 968 SUPERFAMILY SSF53383 942 964 5.18E-87 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase TW_RS00755 02e310db423db165f6e74fe485b86caf 968 SUPERFAMILY SSF53383 4 365 2.65E-86 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase TW_RS00755 02e310db423db165f6e74fe485b86caf 968 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 4 963 0.0 T 11-11-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TW_RS00755 02e310db423db165f6e74fe485b86caf 968 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 1 968 23.12 T 11-11-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TW_RS00755 02e310db423db165f6e74fe485b86caf 968 Pfam PF00266 Aminotransferase class-V 591 737 4.2E-6 T 11-11-2016 IPR000192 Aminotransferase class V domain TW_RS00755 02e310db423db165f6e74fe485b86caf 968 Gene3D G3DSA:3.40.640.10 514 749 1.3E-37 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TW_RS00755 02e310db423db165f6e74fe485b86caf 968 Gene3D G3DSA:3.40.640.10 71 285 1.5E-8 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TW_RS00755 02e310db423db165f6e74fe485b86caf 968 Pfam PF02347 Glycine cleavage system P-protein 3 413 3.6E-144 T 11-11-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TW_RS01895 a455e1ec6a2b95fc61f89399a29700eb 504 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 13 502 31.131 T 11-11-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 TW_RS01895 a455e1ec6a2b95fc61f89399a29700eb 504 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 13 501 1.1E-127 T 11-11-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 TW_RS01895 a455e1ec6a2b95fc61f89399a29700eb 504 Pfam PF02637 GatB domain 358 501 3.9E-29 T 11-11-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 TW_RS01895 a455e1ec6a2b95fc61f89399a29700eb 504 SUPERFAMILY SSF89095 354 501 1.88E-16 T 11-11-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 TW_RS01895 a455e1ec6a2b95fc61f89399a29700eb 504 SUPERFAMILY SSF55931 16 325 2.29E-99 T 11-11-2016 TW_RS01895 a455e1ec6a2b95fc61f89399a29700eb 504 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 168 182 - T 11-11-2016 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 TW_RS01895 a455e1ec6a2b95fc61f89399a29700eb 504 SMART SM00845 356 501 8.9E-32 T 11-11-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 TW_RS01895 a455e1ec6a2b95fc61f89399a29700eb 504 Pfam PF02934 GatB/GatE catalytic domain 17 317 4.0E-96 T 11-11-2016 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 SUPERFAMILY SSF55666 151 260 1.16E-21 T 11-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 Gene3D G3DSA:3.30.230.70 353 584 1.4E-75 T 11-11-2016 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 Gene3D G3DSA:3.30.230.70 9 253 4.0E-75 T 11-11-2016 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 Pfam PF01138 3' exoribonuclease family, domain 1 19 150 2.9E-16 T 11-11-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 Pfam PF01138 3' exoribonuclease family, domain 1 362 494 5.5E-14 T 11-11-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 Pfam PF00013 KH domain 597 654 7.1E-12 T 11-11-2016 IPR004088 K Homology domain, type 1 GO:0003723 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 SUPERFAMILY SSF46915 260 364 1.02E-10 T 11-11-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 SMART SM00316 663 737 2.2E-12 T 11-11-2016 IPR022967 RNA-binding domain, S1 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 Pfam PF00575 S1 RNA binding domain 664 730 7.6E-9 T 11-11-2016 IPR003029 S1 domain GO:0003676 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 Gene3D G3DSA:3.30.1370.10 592 662 1.7E-22 T 11-11-2016 IPR004088 K Homology domain, type 1 GO:0003723 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 PIRSF PIRSF005499 6 738 1.2E-259 T 11-11-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 8 736 25.912 T 11-11-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 3 736 0.0 T 11-11-2016 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 Gene3D G3DSA:1.10.10.400 259 352 4.1E-9 T 11-11-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 SUPERFAMILY SSF54211 335 506 8.6E-40 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 SUPERFAMILY SSF55666 488 587 3.21E-22 T 11-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 Gene3D G3DSA:2.40.50.140 663 734 1.1E-12 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 SUPERFAMILY SSF54211 7 150 6.58E-44 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 16 735 3.4E-239 T 11-11-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 Pfam PF03725 3' exoribonuclease family, domain 2 497 570 4.0E-5 T 11-11-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 SMART SM00322 593 658 1.9E-13 T 11-11-2016 IPR004087 K Homology domain GO:0003676 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 SUPERFAMILY SSF54791 589 700 8.01E-20 T 11-11-2016 IPR004088 K Homology domain, type 1 GO:0003723 TW_RS01845 f14cd8308832cd6d498e919bda1225aa 738 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 301 357 7.7E-5 T 11-11-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TW_RS03730 7f201d18f99cf7aa8d7e5d8242229dfb 203 SUPERFAMILY SSF100950 3 196 5.72E-42 T 11-11-2016 TW_RS03730 7f201d18f99cf7aa8d7e5d8242229dfb 203 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 42 184 2.5E-28 T 11-11-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase TW_RS03730 7f201d18f99cf7aa8d7e5d8242229dfb 203 Gene3D G3DSA:3.40.50.10420 3 196 1.2E-38 T 11-11-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain TW_RS03730 7f201d18f99cf7aa8d7e5d8242229dfb 203 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 36 184 1.1E-37 T 11-11-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 Gene3D G3DSA:4.10.950.10 197 272 3.9E-32 T 11-11-2016 IPR014726 Ribosomal protein L2, domain 3 TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.431 T 11-11-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 Gene3D G3DSA:2.30.30.30 120 196 2.5E-28 T 11-11-2016 IPR014722 Ribosomal protein L2 domain 2 TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 SUPERFAMILY SSF50249 2 125 9.6E-48 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 SMART SM01382 125 253 1.2E-85 T 11-11-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 3.1E-123 T 11-11-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 11-11-2016 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 127 251 1.1E-53 T 11-11-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 SUPERFAMILY SSF50104 127 271 9.03E-56 T 11-11-2016 IPR008991 Translation protein SH3-like domain TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 SMART SM01383 42 119 3.4E-42 T 11-11-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 Gene3D G3DSA:2.40.50.140 1 115 1.9E-48 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 119 1.4E-33 T 11-11-2016 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01155 5c926327d0e0e9cb1f902fc1bf3600f6 277 PIRSF PIRSF002158 13 275 4.0E-97 T 11-11-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03930 f3ca3d47c4c4d41fb4fcf6a6532ca158 522 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 6 359 3.4E-111 T 11-11-2016 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 TW_RS03930 f3ca3d47c4c4d41fb4fcf6a6532ca158 522 SUPERFAMILY SSF48019 250 363 2.04E-12 T 11-11-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TW_RS03930 f3ca3d47c4c4d41fb4fcf6a6532ca158 522 Gene3D G3DSA:1.20.272.10 250 359 2.2E-10 T 11-11-2016 TW_RS03930 f3ca3d47c4c4d41fb4fcf6a6532ca158 522 SUPERFAMILY SSF52540 36 227 1.09E-50 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03930 f3ca3d47c4c4d41fb4fcf6a6532ca158 522 Gene3D G3DSA:3.40.50.300 17 169 1.6E-55 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03930 f3ca3d47c4c4d41fb4fcf6a6532ca158 522 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 250 361 4.4E-10 T 11-11-2016 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 TW_RS03930 f3ca3d47c4c4d41fb4fcf6a6532ca158 522 Gene3D G3DSA:1.10.8.60 170 237 1.6E-17 T 11-11-2016 TW_RS03930 f3ca3d47c4c4d41fb4fcf6a6532ca158 522 SMART SM00382 39 185 5.7E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS03930 f3ca3d47c4c4d41fb4fcf6a6532ca158 522 Pfam PF13177 DNA polymerase III, delta subunit 23 180 5.2E-36 T 11-11-2016 TW_RS02205 6b0b51fab3467630bf1a436d453cc15c 364 SUPERFAMILY SSF159283 303 356 4.05E-12 T 11-11-2016 TW_RS02205 6b0b51fab3467630bf1a436d453cc15c 364 Pfam PF01050 Mannose-6-phosphate isomerase 323 362 2.4E-5 T 11-11-2016 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 TW_RS02205 6b0b51fab3467630bf1a436d453cc15c 364 Pfam PF00483 Nucleotidyl transferase 9 287 1.0E-45 T 11-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TW_RS02205 6b0b51fab3467630bf1a436d453cc15c 364 Gene3D G3DSA:3.90.550.10 5 276 1.7E-72 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS02205 6b0b51fab3467630bf1a436d453cc15c 364 SUPERFAMILY SSF53448 7 287 7.68E-52 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 395 46.808 T 11-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 Pfam PF02772 S-adenosylmethionine synthetase, central domain 124 243 3.3E-38 T 11-11-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 SUPERFAMILY SSF55973 2 106 5.49E-36 T 11-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 PIRSF PIRSF000497 1 394 1.3E-155 T 11-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 2 97 9.8E-33 T 11-11-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 11-11-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 Gene3D G3DSA:3.30.300.10 256 383 2.1E-57 T 11-11-2016 TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 3 383 7.6E-149 T 11-11-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 246 382 2.9E-60 T 11-11-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 Gene3D G3DSA:3.30.300.10 146 244 2.8E-35 T 11-11-2016 TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 Gene3D G3DSA:3.30.300.10 8 145 6.1E-35 T 11-11-2016 TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 SUPERFAMILY SSF55973 122 244 1.68E-40 T 11-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TW_RS02185 d7b108cdd77019543ff2afbd6d683fbd 395 SUPERFAMILY SSF55973 246 384 1.22E-58 T 11-11-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TW_RS00525 a6f9c00035874ab45fb76c1e34512329 239 Pfam PF00005 ABC transporter 22 160 5.7E-18 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS00525 a6f9c00035874ab45fb76c1e34512329 239 Gene3D G3DSA:3.40.50.300 2 212 3.4E-41 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00525 a6f9c00035874ab45fb76c1e34512329 239 SUPERFAMILY SSF52540 3 212 3.85E-41 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00525 a6f9c00035874ab45fb76c1e34512329 239 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS02740 d2e6e08f21d42f386dded9d205695fdc 939 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 92 933 0.0 T 11-11-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TW_RS02740 d2e6e08f21d42f386dded9d205695fdc 939 Gene3D G3DSA:3.40.50.970 520 760 1.3E-93 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS02740 d2e6e08f21d42f386dded9d205695fdc 939 SUPERFAMILY SSF52518 105 513 1.18E-114 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS02740 d2e6e08f21d42f386dded9d205695fdc 939 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 148 341 7.6E-11 T 11-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TW_RS02740 d2e6e08f21d42f386dded9d205695fdc 939 SUPERFAMILY SSF52518 522 755 2.02E-78 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS02740 d2e6e08f21d42f386dded9d205695fdc 939 Gene3D G3DSA:3.40.50.970 106 513 7.8E-131 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS02740 d2e6e08f21d42f386dded9d205695fdc 939 PIRSF PIRSF000156 70 937 0.0 T 11-11-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TW_RS02740 d2e6e08f21d42f386dded9d205695fdc 939 SUPERFAMILY SSF52922 759 935 2.27E-45 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TW_RS02740 d2e6e08f21d42f386dded9d205695fdc 939 Gene3D G3DSA:3.40.50.920 764 933 1.2E-56 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TW_RS04145 2f7a6065a31952c6f314f8dc44778553 143 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 47 84 - T 11-11-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TW_RS04145 2f7a6065a31952c6f314f8dc44778553 143 SUPERFAMILY SSF53927 1 140 1.02E-46 T 11-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 TW_RS04145 2f7a6065a31952c6f314f8dc44778553 143 Gene3D G3DSA:3.40.140.10 1 140 2.2E-52 T 11-11-2016 TW_RS04145 2f7a6065a31952c6f314f8dc44778553 143 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 143 40.726 T 11-11-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 TW_RS04145 2f7a6065a31952c6f314f8dc44778553 143 Pfam PF14437 MafB19-like deaminase 1 143 8.8E-31 T 11-11-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 TW_RS01175 acab283c6bd9590a50436415096b9461 142 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.353 T 11-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01175 acab283c6bd9590a50436415096b9461 142 Gene3D G3DSA:3.90.1170.10 24 137 7.5E-50 T 11-11-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TW_RS01175 acab283c6bd9590a50436415096b9461 142 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 11-11-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01175 acab283c6bd9590a50436415096b9461 142 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 11-11-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01175 acab283c6bd9590a50436415096b9461 142 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.1E-39 T 11-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01175 acab283c6bd9590a50436415096b9461 142 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.1E-39 T 11-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01175 acab283c6bd9590a50436415096b9461 142 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.1E-39 T 11-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01175 acab283c6bd9590a50436415096b9461 142 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.1E-39 T 11-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01175 acab283c6bd9590a50436415096b9461 142 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.5E-45 T 11-11-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TW_RS01175 acab283c6bd9590a50436415096b9461 142 SUPERFAMILY SSF54686 1 137 5.49E-53 T 11-11-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TW_RS01175 acab283c6bd9590a50436415096b9461 142 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 2.4E-54 T 11-11-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS04005 806764fd559a8083ca152f9525b69913 419 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 95 1.5E-24 T 11-11-2016 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TW_RS04005 806764fd559a8083ca152f9525b69913 419 SMART SM01210 316 411 4.9E-30 T 11-11-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TW_RS04005 806764fd559a8083ca152f9525b69913 419 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 96 281 4.2E-55 T 11-11-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TW_RS04005 806764fd559a8083ca152f9525b69913 419 Gene3D G3DSA:3.30.1490.20 119 175 1.0E-9 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TW_RS04005 806764fd559a8083ca152f9525b69913 419 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 409 4.4E-121 T 11-11-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TW_RS04005 806764fd559a8083ca152f9525b69913 419 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 317 408 1.5E-21 T 11-11-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TW_RS04005 806764fd559a8083ca152f9525b69913 419 SUPERFAMILY SSF51246 314 409 4.32E-20 T 11-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS04005 806764fd559a8083ca152f9525b69913 419 Gene3D G3DSA:3.30.470.20 177 308 2.1E-48 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TW_RS04005 806764fd559a8083ca152f9525b69913 419 Gene3D G3DSA:3.40.50.20 1 88 6.2E-24 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS04005 806764fd559a8083ca152f9525b69913 419 SUPERFAMILY SSF56059 97 306 1.61E-48 T 11-11-2016 TW_RS04005 806764fd559a8083ca152f9525b69913 419 SUPERFAMILY SSF52440 1 96 8.92E-23 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS04005 806764fd559a8083ca152f9525b69913 419 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 411 34.283 T 11-11-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TW_RS04005 806764fd559a8083ca152f9525b69913 419 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 275 282 - T 11-11-2016 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TW_RS04005 806764fd559a8083ca152f9525b69913 419 SMART SM01209 96 281 6.4E-85 T 11-11-2016 TW_RS04005 806764fd559a8083ca152f9525b69913 419 Gene3D G3DSA:3.90.600.10 316 408 1.4E-22 T 11-11-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Pfam PF00562 RNA polymerase Rpb2, domain 6 631 1045 2.9E-148 T 11-11-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Pfam PF04560 RNA polymerase Rpb2, domain 7 1047 1121 2.0E-25 T 11-11-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Pfam PF04561 RNA polymerase Rpb2, domain 2 169 366 1.2E-24 T 11-11-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Pfam PF04563 RNA polymerase beta subunit 35 410 7.4E-23 T 11-11-2016 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Gene3D G3DSA:3.90.1100.10 572 626 2.5E-141 T 11-11-2016 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Gene3D G3DSA:3.90.1100.10 355 503 2.5E-141 T 11-11-2016 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Gene3D G3DSA:3.90.1100.10 28 169 2.5E-141 T 11-11-2016 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Gene3D G3DSA:3.90.1110.10 171 340 1.6E-54 T 11-11-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Gene3D G3DSA:2.40.50.150 735 866 1.4E-50 T 11-11-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 ProSitePatterns PS01166 RNA polymerases beta chain signature. 870 882 - T 11-11-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Gene3D G3DSA:2.30.150.10 504 569 4.5E-28 T 11-11-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 245 841 4.8E-284 T 11-11-2016 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 SUPERFAMILY SSF64484 21 1126 0.0 T 11-11-2016 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Gene3D G3DSA:2.40.270.10 699 726 8.1E-75 T 11-11-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Gene3D G3DSA:2.40.270.10 867 1023 8.1E-75 T 11-11-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Pfam PF04565 RNA polymerase Rpb2, domain 3 425 493 1.6E-27 T 11-11-2016 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 21 1123 12.039 T 11-11-2016 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Pfam PF10385 RNA polymerase beta subunit external 1 domain 503 569 1.1E-25 T 11-11-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00405 113b613433b53303cbaf1bd3387c4a00 1155 Gene3D G3DSA:2.40.50.100 628 698 6.9E-24 T 11-11-2016 TW_RS04070 73153747fb3fddd1bc14b11a4a2a8ba7 447 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 344 427 1.2E-5 T 11-11-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TW_RS04070 73153747fb3fddd1bc14b11a4a2a8ba7 447 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 5 158 7.6E-36 T 11-11-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TW_RS04070 73153747fb3fddd1bc14b11a4a2a8ba7 447 SUPERFAMILY SSF69075 340 427 4.18E-6 T 11-11-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TW_RS04070 73153747fb3fddd1bc14b11a4a2a8ba7 447 SUPERFAMILY SSF69742 2 160 6.15E-36 T 11-11-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TW_RS04070 73153747fb3fddd1bc14b11a4a2a8ba7 447 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 173 267 1.7E-6 T 11-11-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TW_RS04070 73153747fb3fddd1bc14b11a4a2a8ba7 447 PIRSF PIRSF000445 1 442 3.6E-109 T 11-11-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TW_RS04070 73153747fb3fddd1bc14b11a4a2a8ba7 447 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 101 124 - T 11-11-2016 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TW_RS04070 73153747fb3fddd1bc14b11a4a2a8ba7 447 Gene3D G3DSA:3.40.50.720 167 326 2.4E-16 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS04070 73153747fb3fddd1bc14b11a4a2a8ba7 447 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 1 428 20.632 T 11-11-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TW_RS04070 73153747fb3fddd1bc14b11a4a2a8ba7 447 SUPERFAMILY SSF51735 169 263 1.41E-7 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00600 37d7575f11f4ad21ce784dc5baa76382 305 Pfam PF01513 ATP-NAD kinase 11 281 8.5E-51 T 11-11-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 TW_RS00600 37d7575f11f4ad21ce784dc5baa76382 305 Hamap MF_00361 NAD kinase [nadK]. 27 302 26.868 T 11-11-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 TW_RS00600 37d7575f11f4ad21ce784dc5baa76382 305 Gene3D G3DSA:3.40.50.10330 10 158 6.0E-25 T 11-11-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 TW_RS00600 37d7575f11f4ad21ce784dc5baa76382 305 SUPERFAMILY SSF111331 82 303 3.66E-68 T 11-11-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain TW_RS00600 37d7575f11f4ad21ce784dc5baa76382 305 Gene3D G3DSA:2.60.200.30 159 276 7.1E-38 T 11-11-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 TW_RS01465 d00d64c2f22dd514eb2c53a7d7d59c87 824 SUPERFAMILY SSF101904 511 788 7.59E-29 T 11-11-2016 TW_RS01465 d00d64c2f22dd514eb2c53a7d7d59c87 824 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 665 707 4.2E-6 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TW_RS01465 d00d64c2f22dd514eb2c53a7d7d59c87 824 Gene3D G3DSA:3.90.199.10 346 411 7.5E-105 T 11-11-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 TW_RS01465 d00d64c2f22dd514eb2c53a7d7d59c87 824 Gene3D G3DSA:3.90.199.10 44 247 7.5E-105 T 11-11-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 TW_RS01465 d00d64c2f22dd514eb2c53a7d7d59c87 824 Gene3D G3DSA:2.120.10.90 557 796 2.1E-22 T 11-11-2016 TW_RS01465 d00d64c2f22dd514eb2c53a7d7d59c87 824 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 45 484 1.3E-144 T 11-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01465 d00d64c2f22dd514eb2c53a7d7d59c87 824 SUPERFAMILY SSF56719 44 498 5.1E-154 T 11-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TW_RS01465 d00d64c2f22dd514eb2c53a7d7d59c87 824 SMART SM00434 24 477 3.5E-207 T 11-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01465 d00d64c2f22dd514eb2c53a7d7d59c87 824 Gene3D G3DSA:3.30.1360.40 248 345 6.3E-26 T 11-11-2016 IPR024946 Arginine repressor C-terminal-like domain TW_RS01550 f6aa776a1ea59c541d6df115c83f4856 453 Pfam PF02875 Mur ligase family, glutamate ligase domain 298 349 3.8E-7 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS01550 f6aa776a1ea59c541d6df115c83f4856 453 Gene3D G3DSA:3.40.1190.10 9 292 1.5E-77 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS01550 f6aa776a1ea59c541d6df115c83f4856 453 TIGRFAM TIGR01499 folC: bifunctional protein FolC 16 448 6.4E-84 T 11-11-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TW_RS01550 f6aa776a1ea59c541d6df115c83f4856 453 Pfam PF08245 Mur ligase middle domain 35 276 3.7E-15 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS01550 f6aa776a1ea59c541d6df115c83f4856 453 SUPERFAMILY SSF53244 299 449 3.66E-18 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS01550 f6aa776a1ea59c541d6df115c83f4856 453 SUPERFAMILY SSF53623 9 295 3.01E-74 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS01550 f6aa776a1ea59c541d6df115c83f4856 453 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 33 56 - T 11-11-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 TW_RS01550 f6aa776a1ea59c541d6df115c83f4856 453 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 135 150 - T 11-11-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 TW_RS01550 f6aa776a1ea59c541d6df115c83f4856 453 Gene3D G3DSA:3.90.190.20 299 451 4.3E-35 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02755 72b625adc5d31c0c818c9c06a5da520c 82 SUPERFAMILY SSF47336 3 79 7.33E-19 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain TW_RS02755 72b625adc5d31c0c818c9c06a5da520c 82 Hamap MF_01217 Acyl carrier protein [acpP]. 7 81 16.353 T 11-11-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TW_RS02755 72b625adc5d31c0c818c9c06a5da520c 82 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 38 77 7.0E-16 T 11-11-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TW_RS02755 72b625adc5d31c0c818c9c06a5da520c 82 Pfam PF00550 Phosphopantetheine attachment site 11 77 4.5E-12 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain TW_RS02755 72b625adc5d31c0c818c9c06a5da520c 82 Gene3D G3DSA:1.10.1200.10 3 78 1.4E-21 T 11-11-2016 IPR009081 Phosphopantetheine binding ACP domain TW_RS02550 56c0d07194e0485c1b5faa12e0fe646f 201 Pfam PF03861 ANTAR domain 144 195 5.5E-16 T 11-11-2016 IPR005561 ANTAR domain GO:0003723 TW_RS02550 56c0d07194e0485c1b5faa12e0fe646f 201 Gene3D G3DSA:1.10.10.10 143 198 7.3E-21 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS02550 56c0d07194e0485c1b5faa12e0fe646f 201 Gene3D G3DSA:3.40.50.2300 18 136 1.6E-30 T 11-11-2016 TW_RS02550 56c0d07194e0485c1b5faa12e0fe646f 201 PIRSF PIRSF036382 5 201 1.2E-74 T 11-11-2016 IPR008327 Signal transduction response regulator, antiterminator TW_RS02550 56c0d07194e0485c1b5faa12e0fe646f 201 Pfam PF00072 Response regulator receiver domain 18 124 2.2E-25 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TW_RS02550 56c0d07194e0485c1b5faa12e0fe646f 201 SUPERFAMILY SSF52172 17 195 1.01E-46 T 11-11-2016 IPR011006 CheY-like superfamily TW_RS02550 56c0d07194e0485c1b5faa12e0fe646f 201 SMART SM00448 15 124 9.0E-30 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TW_RS02550 56c0d07194e0485c1b5faa12e0fe646f 201 SMART SM01012 140 195 2.7E-18 T 11-11-2016 IPR005561 ANTAR domain GO:0003723 TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 Gene3D G3DSA:3.50.7.10 187 366 3.4E-97 T 11-11-2016 IPR027409 GroEL-like apical domain TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 538 40.045 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 SUPERFAMILY SSF52029 183 374 5.68E-82 T 11-11-2016 IPR027409 GroEL-like apical domain TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 11-11-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020 TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 PRINTS PR00298 60kDa chaperonin signature 82 109 1.5E-69 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 PRINTS PR00298 60kDa chaperonin signature 396 417 1.5E-69 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 PRINTS PR00298 60kDa chaperonin signature 348 373 1.5E-69 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 PRINTS PR00298 60kDa chaperonin signature 266 289 1.5E-69 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 PRINTS PR00298 60kDa chaperonin signature 26 52 1.5E-69 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 1.4E-241 T 11-11-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020 TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 Gene3D G3DSA:1.10.560.10 3 186 2.9E-48 T 11-11-2016 IPR027413 GroEL-like equatorial domain TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 Gene3D G3DSA:1.10.560.10 367 516 2.4E-36 T 11-11-2016 IPR027413 GroEL-like equatorial domain TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 SUPERFAMILY SSF48592 6 133 2.33E-69 T 11-11-2016 TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 SUPERFAMILY SSF48592 404 519 2.33E-69 T 11-11-2016 TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 SUPERFAMILY SSF54849 136 202 9.39E-25 T 11-11-2016 TW_RS01745 637efdc0404276f7126ad371cf1a1dc8 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 4.5E-94 T 11-11-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TW_RS03935 6c6e3a638ccffa795ee30487db95d466 126 Gene3D G3DSA:1.20.5.710 3 53 3.4E-17 T 11-11-2016 TW_RS03935 6c6e3a638ccffa795ee30487db95d466 126 SUPERFAMILY SSF54736 56 126 1.45E-22 T 11-11-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TW_RS03935 6c6e3a638ccffa795ee30487db95d466 126 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 60 126 1.4E-27 T 11-11-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03935 6c6e3a638ccffa795ee30487db95d466 126 SUPERFAMILY SSF48300 5 62 1.96E-13 T 11-11-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03935 6c6e3a638ccffa795ee30487db95d466 126 Gene3D G3DSA:3.30.1390.10 55 126 1.1E-30 T 11-11-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TW_RS03935 6c6e3a638ccffa795ee30487db95d466 126 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 54 9.5E-17 T 11-11-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03935 6c6e3a638ccffa795ee30487db95d466 126 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 126 3.9E-44 T 11-11-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03935 6c6e3a638ccffa795ee30487db95d466 126 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 126 22.787 T 11-11-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03935 6c6e3a638ccffa795ee30487db95d466 126 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 100 3.0E-15 T 11-11-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00775 94e19367a8094e30ad7d1f41e59fe6a3 227 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS00775 94e19367a8094e30ad7d1f41e59fe6a3 227 Gene3D G3DSA:3.40.50.300 3 220 9.8E-56 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00775 94e19367a8094e30ad7d1f41e59fe6a3 227 SUPERFAMILY SSF52540 8 213 1.36E-55 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00775 94e19367a8094e30ad7d1f41e59fe6a3 227 SMART SM00382 27 206 1.0E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00775 94e19367a8094e30ad7d1f41e59fe6a3 227 Pfam PF00005 ABC transporter 27 161 1.2E-28 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS02660 6e5e0b3dbf5e46464417ea78665199db 163 SMART SM01323 1 81 1.4E-17 T 11-11-2016 IPR003849 Preprotein translocase YajC TW_RS02660 6e5e0b3dbf5e46464417ea78665199db 163 Pfam PF02699 Preprotein translocase subunit 7 79 1.5E-11 T 11-11-2016 IPR003849 Preprotein translocase YajC TW_RS00105 b1b4565414f27fb569389955479cebe4 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 450 9.1E-22 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 SUPERFAMILY SSF55424 347 457 1.24E-24 T 11-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 1.1E-31 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 1.1E-31 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 1.1E-31 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 1.1E-31 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.1E-31 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 Gene3D G3DSA:3.50.50.60 9 144 6.3E-26 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PIRSF PIRSF000350 2 459 1.7E-66 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 Gene3D G3DSA:3.50.50.60 145 337 2.9E-45 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 SUPERFAMILY SSF51905 5 337 3.44E-46 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 328 8.5E-55 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 42 57 7.9E-50 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 7.9E-50 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 7.9E-50 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 7.9E-50 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 7.9E-50 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 7.9E-50 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 7.9E-50 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 7.9E-50 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 7.9E-50 T 11-11-2016 TW_RS00105 b1b4565414f27fb569389955479cebe4 467 Gene3D G3DSA:3.30.390.30 343 457 2.5E-25 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 Pfam PF00162 Phosphoglycerate kinase 14 387 6.7E-127 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 PRINTS PR00477 Phosphoglycerate kinase family signature 143 165 4.1E-75 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 PRINTS PR00477 Phosphoglycerate kinase family signature 316 341 4.1E-75 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 PRINTS PR00477 Phosphoglycerate kinase family signature 9 25 4.1E-75 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 PRINTS PR00477 Phosphoglycerate kinase family signature 197 216 4.1E-75 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 PRINTS PR00477 Phosphoglycerate kinase family signature 373 390 4.1E-75 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 PRINTS PR00477 Phosphoglycerate kinase family signature 111 126 4.1E-75 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 PRINTS PR00477 Phosphoglycerate kinase family signature 174 196 4.1E-75 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 4.1E-75 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 PRINTS PR00477 Phosphoglycerate kinase family signature 349 360 4.1E-75 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 PIRSF PIRSF000724 3 395 1.7E-129 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 Gene3D G3DSA:3.40.50.1270 186 385 4.9E-68 T 11-11-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 SUPERFAMILY SSF53748 14 395 1.88E-124 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 395 36.321 T 11-11-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02500 23170463957dae9a1688c92cfea6648a 395 Gene3D G3DSA:3.40.50.1260 15 185 6.0E-52 T 11-11-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS01135 79a270273a02d98821bd8e94956532a8 102 SUPERFAMILY SSF54999 5 102 5.89E-34 T 11-11-2016 IPR027486 Ribosomal protein S10 domain TW_RS01135 79a270273a02d98821bd8e94956532a8 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 8.0E-20 T 11-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01135 79a270273a02d98821bd8e94956532a8 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 8.0E-20 T 11-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01135 79a270273a02d98821bd8e94956532a8 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 8.0E-20 T 11-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01135 79a270273a02d98821bd8e94956532a8 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.9E-31 T 11-11-2016 IPR027486 Ribosomal protein S10 domain TW_RS01135 79a270273a02d98821bd8e94956532a8 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 11-11-2016 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01135 79a270273a02d98821bd8e94956532a8 102 SMART SM01403 7 101 1.4E-47 T 11-11-2016 IPR027486 Ribosomal protein S10 domain TW_RS01135 79a270273a02d98821bd8e94956532a8 102 Gene3D G3DSA:3.30.70.600 4 102 7.1E-39 T 11-11-2016 IPR027486 Ribosomal protein S10 domain TW_RS01135 79a270273a02d98821bd8e94956532a8 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 25.295 T 11-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01135 79a270273a02d98821bd8e94956532a8 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 6.0E-42 T 11-11-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01080 9a10f5736d2e8013b8ca69d57a7b27cf 673 Gene3D G3DSA:2.40.50.140 28 121 2.8E-25 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01080 9a10f5736d2e8013b8ca69d57a7b27cf 673 Pfam PF00270 DEAD/DEAH box helicase 270 404 1.0E-14 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TW_RS01080 9a10f5736d2e8013b8ca69d57a7b27cf 673 Gene3D G3DSA:3.40.50.300 233 424 1.8E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01080 9a10f5736d2e8013b8ca69d57a7b27cf 673 SUPERFAMILY SSF52540 171 422 5.13E-48 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01080 9a10f5736d2e8013b8ca69d57a7b27cf 673 SMART SM00487 242 428 2.0E-27 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TW_RS01080 9a10f5736d2e8013b8ca69d57a7b27cf 673 SMART SM00490 474 563 6.2E-17 T 11-11-2016 IPR001650 Helicase, C-terminal TW_RS01080 9a10f5736d2e8013b8ca69d57a7b27cf 673 SUPERFAMILY SSF50249 4 156 1.71E-30 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01080 9a10f5736d2e8013b8ca69d57a7b27cf 673 Gene3D G3DSA:3.40.50.300 440 611 9.6E-38 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01080 9a10f5736d2e8013b8ca69d57a7b27cf 673 SUPERFAMILY SSF52540 266 317 7.99E-34 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01080 9a10f5736d2e8013b8ca69d57a7b27cf 673 SUPERFAMILY SSF52540 491 590 7.99E-34 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01080 9a10f5736d2e8013b8ca69d57a7b27cf 673 Pfam PF00271 Helicase conserved C-terminal domain 447 563 1.8E-18 T 11-11-2016 IPR001650 Helicase, C-terminal TW_RS01080 9a10f5736d2e8013b8ca69d57a7b27cf 673 Pfam PF17191 RecG wedge domain 6 139 4.9E-14 T 11-11-2016 IPR033454 RecG, wedge domain TW_RS00630 8c5af715a774a33e4945333a4b156e74 305 ProSitePatterns PS01057 SAICAR synthetase signature 1. 112 126 - T 11-11-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TW_RS00630 8c5af715a774a33e4945333a4b156e74 305 Gene3D G3DSA:3.30.200.20 11 123 8.3E-34 T 11-11-2016 TW_RS00630 8c5af715a774a33e4945333a4b156e74 305 SUPERFAMILY SSF56104 12 305 3.92E-74 T 11-11-2016 TW_RS00630 8c5af715a774a33e4945333a4b156e74 305 ProSitePatterns PS01058 SAICAR synthetase signature 2. 209 217 - T 11-11-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TW_RS00630 8c5af715a774a33e4945333a4b156e74 305 Gene3D G3DSA:3.30.470.20 124 244 4.4E-37 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TW_RS00630 8c5af715a774a33e4945333a4b156e74 305 Pfam PF01259 SAICAR synthetase 19 268 5.6E-72 T 11-11-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TW_RS00630 8c5af715a774a33e4945333a4b156e74 305 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 16 305 20.455 T 11-11-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TW_RS02375 8fc8948904496996188d6a4a95816945 354 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 22 1.1E-5 T 11-11-2016 IPR027399 Alcohol dehydrogenase GroES-associated TW_RS02375 8fc8948904496996188d6a4a95816945 354 SUPERFAMILY SSF50129 1 160 3.2E-48 T 11-11-2016 IPR011032 GroES-like TW_RS02375 8fc8948904496996188d6a4a95816945 354 Gene3D G3DSA:3.90.180.10 1 176 2.2E-45 T 11-11-2016 IPR011032 GroES-like TW_RS02375 8fc8948904496996188d6a4a95816945 354 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 11-11-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TW_RS02375 8fc8948904496996188d6a4a95816945 354 Gene3D G3DSA:3.40.50.720 177 295 1.5E-34 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS02375 8fc8948904496996188d6a4a95816945 354 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 134 8.1E-26 T 11-11-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TW_RS02375 8fc8948904496996188d6a4a95816945 354 SUPERFAMILY SSF51735 146 313 1.23E-33 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS02375 8fc8948904496996188d6a4a95816945 354 Pfam PF00107 Zinc-binding dehydrogenase 182 302 1.2E-24 T 11-11-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TW_RS00090 c03c10d03fd22dd0ef4be3d49a265dfe 283 PRINTS PR00069 Aldo-keto reductase signature 162 191 4.6E-47 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TW_RS00090 c03c10d03fd22dd0ef4be3d49a265dfe 283 PRINTS PR00069 Aldo-keto reductase signature 201 225 4.6E-47 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TW_RS00090 c03c10d03fd22dd0ef4be3d49a265dfe 283 PRINTS PR00069 Aldo-keto reductase signature 42 66 4.6E-47 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TW_RS00090 c03c10d03fd22dd0ef4be3d49a265dfe 283 PRINTS PR00069 Aldo-keto reductase signature 96 114 4.6E-47 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TW_RS00090 c03c10d03fd22dd0ef4be3d49a265dfe 283 PRINTS PR00069 Aldo-keto reductase signature 128 145 4.6E-47 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TW_RS00090 c03c10d03fd22dd0ef4be3d49a265dfe 283 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 128 145 - T 11-11-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TW_RS00090 c03c10d03fd22dd0ef4be3d49a265dfe 283 SUPERFAMILY SSF51430 12 273 8.12E-83 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain TW_RS00090 c03c10d03fd22dd0ef4be3d49a265dfe 283 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 46 63 - T 11-11-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TW_RS00090 c03c10d03fd22dd0ef4be3d49a265dfe 283 Gene3D G3DSA:3.20.20.100 12 276 1.3E-92 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain TW_RS00090 c03c10d03fd22dd0ef4be3d49a265dfe 283 Pfam PF00248 Aldo/keto reductase family 28 266 3.5E-45 T 11-11-2016 IPR023210 NADP-dependent oxidoreductase domain TW_RS00090 c03c10d03fd22dd0ef4be3d49a265dfe 283 PIRSF PIRSF000097 7 276 4.4E-78 T 11-11-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 812 0.0 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 Gene3D G3DSA:3.90.1440.10 234 351 2.0E-43 T 11-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 Gene3D G3DSA:3.40.50.300 4 228 1.4E-110 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 Gene3D G3DSA:3.40.50.300 352 399 1.4E-110 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 ProSitePatterns PS01312 SecA family signature. 483 498 - T 11-11-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 322 344 3.5E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 359 376 3.5E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 396 409 3.5E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 117 127 3.5E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 63 87 3.5E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 101 115 3.5E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 PRINTS PR00906 SecA protein signature 170 190 3.5E-69 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 SMART SM00957 6 385 5.1E-252 T 11-11-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 Gene3D G3DSA:1.10.3060.10 644 823 1.6E-51 T 11-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 SUPERFAMILY SSF52540 6 228 5.71E-73 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 SUPERFAMILY SSF52540 351 398 5.71E-73 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 SUPERFAMILY SSF52540 400 603 1.5E-53 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 826 19.215 T 11-11-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 Pfam PF07516 SecA Wing and Scaffold domain 613 823 6.1E-61 T 11-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 Pfam PF01043 SecA preprotein cross-linking domain 235 341 4.7E-33 T 11-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 Pfam PF07517 SecA DEAD-like domain 8 384 1.7E-117 T 11-11-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 SMART SM00958 229 341 3.4E-56 T 11-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 SUPERFAMILY SSF81886 616 828 1.19E-64 T 11-11-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 Gene3D G3DSA:3.40.50.300 400 614 1.5E-86 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00730 e6fe62e1714c3f94f99c362484d677c8 847 SUPERFAMILY SSF81767 232 351 1.03E-39 T 11-11-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 TW_RS03165 e32b90b43deb999b81cea11d22395e6f 298 Pfam PF00482 Type II secretion system (T2SS), protein F 166 289 1.7E-13 T 11-11-2016 IPR018076 Type II secretion system F domain TW_RS03665 64b2b4c378771a3ef4880ef37e741a7b 187 SUPERFAMILY SSF50715 5 182 1.43E-39 T 11-11-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TW_RS03665 64b2b4c378771a3ef4880ef37e741a7b 187 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 6 93 1.0E-31 T 11-11-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TW_RS03665 64b2b4c378771a3ef4880ef37e741a7b 187 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 7 174 1.7E-34 T 11-11-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TW_RS03665 64b2b4c378771a3ef4880ef37e741a7b 187 Gene3D G3DSA:2.170.120.20 96 183 9.9E-18 T 11-11-2016 IPR020057 Ribosomal protein L25, beta domain TW_RS03665 64b2b4c378771a3ef4880ef37e741a7b 187 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 178 22.705 T 11-11-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TW_RS03665 64b2b4c378771a3ef4880ef37e741a7b 187 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 99 176 1.1E-15 T 11-11-2016 IPR020057 Ribosomal protein L25, beta domain TW_RS03665 64b2b4c378771a3ef4880ef37e741a7b 187 Pfam PF01386 Ribosomal L25p family 7 90 4.8E-18 T 11-11-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TW_RS03665 64b2b4c378771a3ef4880ef37e741a7b 187 Gene3D G3DSA:2.40.240.10 5 93 3.7E-21 T 11-11-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TW_RS01630 59d36945b4bb4b69a2bdd40ddd1add48 448 SMART SM00382 101 260 6.8E-6 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS01630 59d36945b4bb4b69a2bdd40ddd1add48 448 SMART SM00962 102 294 1.3E-76 T 11-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TW_RS01630 59d36945b4bb4b69a2bdd40ddd1add48 448 SUPERFAMILY SSF47364 2 94 3.89E-17 T 11-11-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TW_RS01630 59d36945b4bb4b69a2bdd40ddd1add48 448 SUPERFAMILY SSF47446 302 410 4.84E-23 T 11-11-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TW_RS01630 59d36945b4bb4b69a2bdd40ddd1add48 448 Pfam PF00448 SRP54-type protein, GTPase domain 102 294 1.2E-57 T 11-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TW_RS01630 59d36945b4bb4b69a2bdd40ddd1add48 448 Gene3D G3DSA:1.10.260.30 352 410 6.7E-22 T 11-11-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TW_RS01630 59d36945b4bb4b69a2bdd40ddd1add48 448 SUPERFAMILY SSF52540 101 295 1.31E-39 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01630 59d36945b4bb4b69a2bdd40ddd1add48 448 Gene3D G3DSA:3.40.50.300 100 295 7.7E-56 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01630 59d36945b4bb4b69a2bdd40ddd1add48 448 Gene3D G3DSA:1.20.120.140 4 91 8.4E-19 T 11-11-2016 TW_RS01630 59d36945b4bb4b69a2bdd40ddd1add48 448 Pfam PF02881 SRP54-type protein, helical bundle domain 8 84 1.7E-11 T 11-11-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TW_RS01630 59d36945b4bb4b69a2bdd40ddd1add48 448 SMART SM00963 3 88 1.9E-17 T 11-11-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TW_RS01630 59d36945b4bb4b69a2bdd40ddd1add48 448 Pfam PF02978 Signal peptide binding domain 320 409 1.9E-20 T 11-11-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TW_RS03625 7bca30077e402cad9017cd3e6e7b31cd 314 SUPERFAMILY SSF53613 3 302 1.01E-60 T 11-11-2016 IPR029056 Ribokinase-like TW_RS03625 7bca30077e402cad9017cd3e6e7b31cd 314 Pfam PF00294 pfkB family carbohydrate kinase 7 297 1.7E-29 T 11-11-2016 IPR011611 Carbohydrate kinase PfkB TW_RS03625 7bca30077e402cad9017cd3e6e7b31cd 314 Gene3D G3DSA:3.40.1190.20 3 298 4.0E-62 T 11-11-2016 IPR029056 Ribokinase-like TW_RS00470 c4a4566917799d73abbb9dda57b38b82 542 Pfam PF01808 AICARFT/IMPCHase bienzyme 139 476 3.0E-99 T 11-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TW_RS00470 c4a4566917799d73abbb9dda57b38b82 542 SUPERFAMILY SSF53927 230 542 1.4E-106 T 11-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 TW_RS00470 c4a4566917799d73abbb9dda57b38b82 542 SUPERFAMILY SSF52335 7 196 7.78E-57 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain TW_RS00470 c4a4566917799d73abbb9dda57b38b82 542 SMART SM00798 139 477 5.7E-149 T 11-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TW_RS00470 c4a4566917799d73abbb9dda57b38b82 542 SMART SM00851 19 134 8.0E-36 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain TW_RS00470 c4a4566917799d73abbb9dda57b38b82 542 PIRSF PIRSF000414 1 542 1.1E-195 T 11-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TW_RS00470 c4a4566917799d73abbb9dda57b38b82 542 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 542 37.962 T 11-11-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TW_RS00470 c4a4566917799d73abbb9dda57b38b82 542 Gene3D G3DSA:3.40.140.20 265 380 4.0E-38 T 11-11-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TW_RS00470 c4a4566917799d73abbb9dda57b38b82 542 Gene3D G3DSA:3.40.50.1380 6 188 1.1E-67 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain TW_RS00470 c4a4566917799d73abbb9dda57b38b82 542 Gene3D G3DSA:3.40.140.20 386 532 1.2E-46 T 11-11-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TW_RS00470 c4a4566917799d73abbb9dda57b38b82 542 Pfam PF02142 MGS-like domain 19 132 1.6E-17 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain TW_RS03635 d094596cebaebf69364084c590dd7db2 284 SUPERFAMILY SSF51658 14 268 2.49E-42 T 11-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TW_RS03635 d094596cebaebf69364084c590dd7db2 284 Gene3D G3DSA:3.20.20.150 5 272 2.7E-37 T 11-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TW_RS03635 d094596cebaebf69364084c590dd7db2 284 Pfam PF01261 Xylose isomerase-like TIM barrel 22 227 1.5E-27 T 11-11-2016 IPR013022 Xylose isomerase-like, TIM barrel domain TW_RS00075 07dd2b51fbf3a45d31c25345b7dd22a6 290 Pfam PF01435 Peptidase family M48 75 286 3.6E-37 T 11-11-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TW_RS00075 07dd2b51fbf3a45d31c25345b7dd22a6 290 Gene3D G3DSA:3.30.2010.10 66 155 3.6E-33 T 11-11-2016 TW_RS00075 07dd2b51fbf3a45d31c25345b7dd22a6 290 Hamap MF_00188 Protease HtpX [htpX]. 7 286 27.225 T 11-11-2016 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 SUPERFAMILY SSF52540 11 271 1.42E-62 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 PRINTS PR00142 RecA protein signature 301 318 1.6E-83 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 PRINTS PR00142 RecA protein signature 169 198 1.6E-83 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 PRINTS PR00142 RecA protein signature 214 242 1.6E-83 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 PRINTS PR00142 RecA protein signature 247 276 1.6E-83 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 PRINTS PR00142 RecA protein signature 97 126 1.6E-83 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 PRINTS PR00142 RecA protein signature 131 160 1.6E-83 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 Gene3D G3DSA:3.30.250.10 272 328 1.3E-24 T 11-11-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 SMART SM00382 61 232 7.6E-10 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 SUPERFAMILY SSF54752 272 329 2.88E-18 T 11-11-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 Gene3D G3DSA:3.40.50.300 33 271 5.8E-82 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 Pfam PF00154 recA bacterial DNA recombination protein 11 272 1.1E-139 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 ProSitePatterns PS00321 recA signature. 217 225 - T 11-11-2016 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 8 326 5.8E-168 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TW_RS03420 01ea524efb79195f26db2da59e6cd656 437 Hamap MF_00268 Protein RecA [recA]. 9 333 51.721 T 11-11-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TW_RS04080 852c2e80b4e58765afcd7fc0ada69fef 441 Pfam PF00772 DnaB-like helicase N terminal domain 6 108 1.4E-30 T 11-11-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 TW_RS04080 852c2e80b4e58765afcd7fc0ada69fef 441 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 7 435 1.1E-154 T 11-11-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 TW_RS04080 852c2e80b4e58765afcd7fc0ada69fef 441 SMART SM00382 199 387 0.0053 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS04080 852c2e80b4e58765afcd7fc0ada69fef 441 Pfam PF03796 DnaB-like helicase C terminal domain 182 434 4.0E-102 T 11-11-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 TW_RS04080 852c2e80b4e58765afcd7fc0ada69fef 441 Gene3D G3DSA:3.40.50.300 169 435 6.3E-103 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04080 852c2e80b4e58765afcd7fc0ada69fef 441 SUPERFAMILY SSF52540 181 427 3.16E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04080 852c2e80b4e58765afcd7fc0ada69fef 441 SUPERFAMILY SSF48024 5 115 2.22E-33 T 11-11-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 TW_RS04080 852c2e80b4e58765afcd7fc0ada69fef 441 Gene3D G3DSA:1.10.860.10 7 109 2.5E-31 T 11-11-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal TW_RS01810 ed7e7e74114a620fbb9a0dee9970d571 172 Pfam PF00430 ATP synthase B/B' CF(0) 17 145 2.2E-24 T 11-11-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TW_RS01810 ed7e7e74114a620fbb9a0dee9970d571 172 Hamap MF_01398 ATP synthase subunit b [atpF]. 10 167 11.574 T 11-11-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TW_RS01810 ed7e7e74114a620fbb9a0dee9970d571 172 SUPERFAMILY SSF81573 72 131 4.84E-11 T 11-11-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain TW_RS01810 ed7e7e74114a620fbb9a0dee9970d571 172 Gene3D G3DSA:1.20.5.620 72 132 5.1E-10 T 11-11-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain TW_RS01810 ed7e7e74114a620fbb9a0dee9970d571 172 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 21 164 8.9E-21 T 11-11-2016 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 TW_RS01780 c786251c2ad5bef36d3267ebe2d4e9ea 285 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 23 277 6.3E-63 T 11-11-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 TW_RS01780 c786251c2ad5bef36d3267ebe2d4e9ea 285 Gene3D G3DSA:3.40.50.150 88 279 7.6E-43 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS01780 c786251c2ad5bef36d3267ebe2d4e9ea 285 SUPERFAMILY SSF53335 64 248 3.23E-37 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS01780 c786251c2ad5bef36d3267ebe2d4e9ea 285 Gene3D G3DSA:1.10.8.10 3 85 8.6E-14 T 11-11-2016 TW_RS01780 c786251c2ad5bef36d3267ebe2d4e9ea 285 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 190 196 - T 11-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TW_RS01780 c786251c2ad5bef36d3267ebe2d4e9ea 285 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 18 279 5.0E-48 T 11-11-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 TW_RS01780 c786251c2ad5bef36d3267ebe2d4e9ea 285 Pfam PF05175 Methyltransferase small domain 103 200 1.0E-9 T 11-11-2016 IPR007848 Methyltransferase small domain GO:0008168 TW_RS01875 893e1c03a1c2ae303e5dd01df223bce5 353 Gene3D G3DSA:3.40.50.620 1 201 1.1E-72 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS01875 893e1c03a1c2ae303e5dd01df223bce5 353 Pfam PF03054 tRNA methyl transferase 1 343 1.7E-106 T 11-11-2016 TW_RS01875 893e1c03a1c2ae303e5dd01df223bce5 353 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 343 7.7E-82 T 11-11-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 TW_RS01875 893e1c03a1c2ae303e5dd01df223bce5 353 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 345 31.908 T 11-11-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 TW_RS01875 893e1c03a1c2ae303e5dd01df223bce5 353 Gene3D G3DSA:2.40.30.10 286 349 9.9E-15 T 11-11-2016 TW_RS01875 893e1c03a1c2ae303e5dd01df223bce5 353 Gene3D G3DSA:2.30.30.280 204 266 1.7E-14 T 11-11-2016 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 TW_RS01875 893e1c03a1c2ae303e5dd01df223bce5 353 SUPERFAMILY SSF52402 1 234 3.09E-40 T 11-11-2016 TW_RS00300 bb37d04ac174070c192e5a3acb20a88f 447 Gene3D G3DSA:3.50.50.60 94 314 9.3E-56 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS00300 bb37d04ac174070c192e5a3acb20a88f 447 Gene3D G3DSA:3.40.50.720 315 439 3.2E-63 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00300 bb37d04ac174070c192e5a3acb20a88f 447 Gene3D G3DSA:3.40.50.720 3 93 3.2E-63 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00300 bb37d04ac174070c192e5a3acb20a88f 447 SUPERFAMILY SSF51971 299 436 6.47E-6 T 11-11-2016 TW_RS00300 bb37d04ac174070c192e5a3acb20a88f 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 164 1.6E-6 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS00300 bb37d04ac174070c192e5a3acb20a88f 447 PIRSF PIRSF000362 1 443 9.3E-152 T 11-11-2016 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 TW_RS00300 bb37d04ac174070c192e5a3acb20a88f 447 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 3.8E-15 T 11-11-2016 TW_RS00300 bb37d04ac174070c192e5a3acb20a88f 447 PRINTS PR00419 Adrenodoxin reductase family signature 28 41 3.8E-15 T 11-11-2016 TW_RS00300 bb37d04ac174070c192e5a3acb20a88f 447 PRINTS PR00419 Adrenodoxin reductase family signature 142 156 3.8E-15 T 11-11-2016 TW_RS00300 bb37d04ac174070c192e5a3acb20a88f 447 SUPERFAMILY SSF51971 3 208 4.3E-50 T 11-11-2016 TW_RS00300 bb37d04ac174070c192e5a3acb20a88f 447 SUPERFAMILY SSF51971 252 290 4.3E-50 T 11-11-2016 TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 2 342 32.816 T 11-11-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 Pfam PF01820 D-ala D-ala ligase N-terminus 4 123 7.4E-27 T 11-11-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 Pfam PF07478 D-ala D-ala ligase C-terminus 140 338 2.3E-47 T 11-11-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 Gene3D G3DSA:3.40.50.20 3 122 1.8E-26 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 PIRSF PIRSF039102 1 347 5.8E-85 T 11-11-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 SUPERFAMILY SSF52440 4 132 3.74E-30 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 SUPERFAMILY SSF56059 133 333 4.47E-36 T 11-11-2016 TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 4 341 6.1E-81 T 11-11-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 Gene3D G3DSA:3.30.1490.20 147 219 1.0E-16 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 Gene3D G3DSA:3.30.470.20 222 341 2.7E-28 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 Gene3D G3DSA:3.30.470.20 123 146 2.7E-28 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 100 111 - T 11-11-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS01390 99044e7b8b08ffc2d05922c4562e46c7 347 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 287 314 - T 11-11-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS00970 f6896d575988e33f106ba383a9ffba0e 407 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 15 392 21.513 T 11-11-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TW_RS00970 f6896d575988e33f106ba383a9ffba0e 407 SUPERFAMILY SSF52402 236 313 3.62E-46 T 11-11-2016 TW_RS00970 f6896d575988e33f106ba383a9ffba0e 407 SUPERFAMILY SSF52402 31 166 3.62E-46 T 11-11-2016 TW_RS00970 f6896d575988e33f106ba383a9ffba0e 407 SUPERFAMILY SSF82829 291 398 3.14E-12 T 11-11-2016 TW_RS00970 f6896d575988e33f106ba383a9ffba0e 407 Pfam PF01171 PP-loop family 31 280 6.3E-34 T 11-11-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TW_RS00970 f6896d575988e33f106ba383a9ffba0e 407 Gene3D G3DSA:3.40.50.620 28 170 5.5E-9 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS00970 f6896d575988e33f106ba383a9ffba0e 407 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 31 164 2.9E-27 T 11-11-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TW_RS01770 5a6e56c4412708104e158749b2756493 454 Pfam PF07497 Rho termination factor, RNA-binding domain 118 190 1.0E-21 T 11-11-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 TW_RS01770 5a6e56c4412708104e158749b2756493 454 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 420 429 - T 11-11-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01770 5a6e56c4412708104e158749b2756493 454 Gene3D G3DSA:2.40.50.140 5 46 3.5E-29 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01770 5a6e56c4412708104e158749b2756493 454 Gene3D G3DSA:2.40.50.140 112 191 3.5E-29 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01770 5a6e56c4412708104e158749b2756493 454 SMART SM00959 6 46 1.6E-5 T 11-11-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 TW_RS01770 5a6e56c4412708104e158749b2756493 454 Gene3D G3DSA:3.40.50.300 221 448 3.1E-51 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01770 5a6e56c4412708104e158749b2756493 454 SUPERFAMILY SSF50249 117 190 9.42E-12 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01770 5a6e56c4412708104e158749b2756493 454 SUPERFAMILY SSF52540 154 430 7.98E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01770 5a6e56c4412708104e158749b2756493 454 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 224 429 1.5E-15 T 11-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 55 108 3.0E-15 T 11-11-2016 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 52 1.4E-10 T 11-11-2016 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 SUPERFAMILY SSF55347 102 235 1.34E-51 T 11-11-2016 TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 SUPERFAMILY SSF51735 2 125 1.17E-28 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 361 39.254 T 11-11-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 Gene3D G3DSA:1.10.1740.10 279 364 1.7E-24 T 11-11-2016 TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 121 202 1.3E-33 T 11-11-2016 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 56 362 2.8E-100 T 11-11-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 SUPERFAMILY SSF69055 266 364 1.03E-19 T 11-11-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 PIRSF PIRSF006205 1 368 2.1E-132 T 11-11-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 Gene3D G3DSA:3.40.50.720 56 125 3.2E-22 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 Gene3D G3DSA:3.40.50.720 2 55 6.8E-14 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00495 2cb0b06c708c5aa6e5ec12b50ba0fe0e 368 Pfam PF13288 DXP reductoisomerase C-terminal domain 235 356 1.9E-28 T 11-11-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Gene3D G3DSA:3.40.50.1380 957 1091 1.9E-34 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 435 549 4.0E-37 T 11-11-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 SUPERFAMILY SSF52440 1 126 9.35E-46 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 SUPERFAMILY SSF52335 957 1092 1.7E-28 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 SUPERFAMILY SSF56059 679 953 3.54E-90 T 11-11-2016 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Gene3D G3DSA:3.40.50.20 541 668 1.7E-54 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Pfam PF02142 MGS-like domain 977 1065 1.7E-15 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 680 880 2.2E-32 T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 129 334 3.8E-65 T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 SUPERFAMILY SSF48108 395 556 7.06E-47 T 11-11-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1086 12.408 T 11-11-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Gene3D G3DSA:1.10.1030.10 400 540 2.1E-44 T 11-11-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 5 1074 0.0 T 11-11-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 9.0E-62 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 9.0E-62 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 9.0E-62 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 9.0E-62 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 9.0E-62 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 9.0E-62 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 9.0E-62 T 11-11-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 SUPERFAMILY SSF52440 560 681 5.18E-43 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Gene3D G3DSA:3.30.470.20 751 954 1.2E-61 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Gene3D G3DSA:3.30.470.20 202 399 4.8E-78 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 844 851 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 715 729 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 SMART SM00851 975 1065 1.6E-21 T 11-11-2016 IPR011607 Methylglyoxal synthase-like domain TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 SMART SM01096 431 549 1.2E-60 T 11-11-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Gene3D G3DSA:3.40.50.20 6 107 2.4E-41 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Gene3D G3DSA:3.30.1490.20 143 201 5.5E-20 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 Gene3D G3DSA:3.30.1490.20 692 750 2.0E-20 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TW_RS02160 014a4650f967ddc517c3a7fb1f6cbe83 1103 SUPERFAMILY SSF56059 128 400 3.01E-102 T 11-11-2016 TW_RS00010 985f20ce96d49a82fb8152cf888423ec 377 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 250 344 2.0E-8 T 11-11-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TW_RS00010 985f20ce96d49a82fb8152cf888423ec 377 SUPERFAMILY SSF55979 250 372 8.37E-10 T 11-11-2016 TW_RS00010 985f20ce96d49a82fb8152cf888423ec 377 Gene3D G3DSA:3.10.150.10 117 246 2.3E-22 T 11-11-2016 TW_RS00010 985f20ce96d49a82fb8152cf888423ec 377 SMART SM00480 17 371 4.2E-55 T 11-11-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TW_RS00010 985f20ce96d49a82fb8152cf888423ec 377 Pfam PF02767 DNA polymerase III beta subunit, central domain 128 245 2.9E-22 T 11-11-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TW_RS00010 985f20ce96d49a82fb8152cf888423ec 377 Gene3D G3DSA:3.10.150.10 258 372 4.6E-18 T 11-11-2016 TW_RS00010 985f20ce96d49a82fb8152cf888423ec 377 SUPERFAMILY SSF55979 1 118 2.88E-22 T 11-11-2016 TW_RS00010 985f20ce96d49a82fb8152cf888423ec 377 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 118 1.5E-22 T 11-11-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TW_RS00010 985f20ce96d49a82fb8152cf888423ec 377 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 359 1.3E-66 T 11-11-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TW_RS00010 985f20ce96d49a82fb8152cf888423ec 377 Gene3D G3DSA:3.10.150.10 1 116 1.2E-23 T 11-11-2016 TW_RS00010 985f20ce96d49a82fb8152cf888423ec 377 PIRSF PIRSF000804 1 373 8.5E-69 T 11-11-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TW_RS00010 985f20ce96d49a82fb8152cf888423ec 377 SUPERFAMILY SSF55979 128 248 2.49E-16 T 11-11-2016 TW_RS02140 8fd3f2f0a3d47260c9ea12d29e7639c3 149 SUPERFAMILY SSF52304 3 146 3.14E-48 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TW_RS02140 8fd3f2f0a3d47260c9ea12d29e7639c3 149 Gene3D G3DSA:3.40.50.9100 4 147 1.5E-51 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TW_RS02140 8fd3f2f0a3d47260c9ea12d29e7639c3 149 Pfam PF01220 Dehydroquinase class II 5 143 2.1E-46 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TW_RS02140 8fd3f2f0a3d47260c9ea12d29e7639c3 149 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 6 144 4.0E-77 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TW_RS02140 8fd3f2f0a3d47260c9ea12d29e7639c3 149 ProSitePatterns PS01029 Dehydroquinase class II signature. 9 26 - T 11-11-2016 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TW_RS02140 8fd3f2f0a3d47260c9ea12d29e7639c3 149 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 149 55.751 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TW_RS02140 8fd3f2f0a3d47260c9ea12d29e7639c3 149 PIRSF PIRSF001399 2 149 8.4E-60 T 11-11-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 SUPERFAMILY SSF88659 163 236 8.22E-20 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 114 127 - T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 PRINTS PR00046 Major sigma-70 factor signature 262 274 2.6E-28 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 PRINTS PR00046 Major sigma-70 factor signature 283 298 2.6E-28 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 PRINTS PR00046 Major sigma-70 factor signature 114 127 2.6E-28 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 PRINTS PR00046 Major sigma-70 factor signature 138 146 2.6E-28 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 PRINTS PR00046 Major sigma-70 factor signature 298 309 2.6E-28 T 11-11-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 Gene3D G3DSA:1.10.10.10 253 322 4.0E-28 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 86 311 2.0E-34 T 11-11-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 1 323 28.353 T 11-11-2016 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 Gene3D G3DSA:1.10.10.10 163 214 9.5E-25 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 Pfam PF04545 Sigma-70, region 4 258 311 2.0E-15 T 11-11-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 SUPERFAMILY SSF88946 22 160 3.01E-53 T 11-11-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 Pfam PF00140 Sigma-70 factor, region 1.2 25 58 4.3E-16 T 11-11-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 86 322 2.0E-108 T 11-11-2016 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 SUPERFAMILY SSF88659 220 322 1.25E-24 T 11-11-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 Pfam PF04539 Sigma-70 region 3 169 245 1.8E-27 T 11-11-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 Gene3D G3DSA:1.10.601.10 21 159 8.4E-67 T 11-11-2016 TW_RS01420 b4208d1aa2962389031f7096366ebe40 323 Pfam PF04542 Sigma-70 region 2 90 159 1.8E-21 T 11-11-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TW_RS03405 5d7e0d761d87eef783a9236f3c60c9a9 706 Pfam PF05345 Putative Ig domain 422 461 2.4E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS03405 5d7e0d761d87eef783a9236f3c60c9a9 706 Pfam PF05345 Putative Ig domain 521 565 3.1E-6 T 11-11-2016 IPR008009 Putative Ig TW_RS03405 5d7e0d761d87eef783a9236f3c60c9a9 706 Pfam PF07861 WisP family N-Terminal Region 54 288 1.3E-154 T 11-11-2016 IPR012503 WisP, N-terminal TW_RS04425 ee1480a836a46eaf1b883ddb9d15cd4b 92 Pfam PF01809 Haemolytic domain 8 72 3.4E-22 T 11-11-2016 IPR002696 Putative membrane protein insertion efficiency factor TW_RS04425 ee1480a836a46eaf1b883ddb9d15cd4b 92 SMART SM01234 6 73 1.2E-28 T 11-11-2016 IPR002696 Putative membrane protein insertion efficiency factor TW_RS04425 ee1480a836a46eaf1b883ddb9d15cd4b 92 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 6 74 20.392 T 11-11-2016 IPR002696 Putative membrane protein insertion efficiency factor TW_RS04425 ee1480a836a46eaf1b883ddb9d15cd4b 92 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 20 74 3.0E-27 T 11-11-2016 IPR002696 Putative membrane protein insertion efficiency factor TW_RS04425 ee1480a836a46eaf1b883ddb9d15cd4b 92 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 10 77 1.3E-18 T 11-11-2016 IPR002696 Putative membrane protein insertion efficiency factor TW_RS01015 3e10961879f0185c9d139d65d41df33c 312 Pfam PF06574 FAD synthetase 13 164 4.6E-43 T 11-11-2016 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS01015 3e10961879f0185c9d139d65d41df33c 312 SUPERFAMILY SSF52374 14 173 2.67E-30 T 11-11-2016 TW_RS01015 3e10961879f0185c9d139d65d41df33c 312 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 17 83 2.3E-8 T 11-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TW_RS01015 3e10961879f0185c9d139d65d41df33c 312 Gene3D G3DSA:3.40.50.620 11 178 1.1E-52 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS01015 3e10961879f0185c9d139d65d41df33c 312 Gene3D G3DSA:2.40.30.30 179 308 7.5E-36 T 11-11-2016 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 TW_RS01015 3e10961879f0185c9d139d65d41df33c 312 Pfam PF01687 Riboflavin kinase 182 307 2.4E-30 T 11-11-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 TW_RS01015 3e10961879f0185c9d139d65d41df33c 312 SMART SM00904 181 308 2.1E-48 T 11-11-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 TW_RS01015 3e10961879f0185c9d139d65d41df33c 312 SUPERFAMILY SSF82114 174 308 2.18E-34 T 11-11-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 TW_RS01015 3e10961879f0185c9d139d65d41df33c 312 PIRSF PIRSF004491 1 312 1.3E-103 T 11-11-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS01015 3e10961879f0185c9d139d65d41df33c 312 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 17 308 1.1E-64 T 11-11-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 Gene3D G3DSA:3.30.930.10 3 229 2.0E-85 T 11-11-2016 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 SMART SM00863 637 681 1.5E-15 T 11-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 SUPERFAMILY SSF50447 438 536 1.55E-12 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 Pfam PF01411 tRNA synthetases class II (A) 6 538 4.0E-171 T 11-11-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 637 681 1.1E-12 T 11-11-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 877 134.204 T 11-11-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 SUPERFAMILY SSF55186 536 696 9.03E-38 T 11-11-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 214 227 1.1E-26 T 11-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 1.1E-26 T 11-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 186 197 1.1E-26 T 11-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 264 280 1.1E-26 T 11-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 PRINTS PR00980 Alanyl-tRNA synthetase signature 288 301 1.1E-26 T 11-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 SUPERFAMILY SSF55681 3 233 7.7E-82 T 11-11-2016 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 SUPERFAMILY SSF101353 234 430 2.09E-52 T 11-11-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TW_RS02105 3f785ecdafc1f70eeb5edd773b33210d 880 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 6 856 5.4E-225 T 11-11-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TW_RS03310 a3e7a0c3479024bd6a0335c0aceeeef3 136 Pfam PF00453 Ribosomal protein L20 3 109 2.0E-42 T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03310 a3e7a0c3479024bd6a0335c0aceeeef3 136 SUPERFAMILY SSF74731 2 116 1.96E-43 T 11-11-2016 TW_RS03310 a3e7a0c3479024bd6a0335c0aceeeef3 136 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 3.0E-13 T 11-11-2016 TW_RS03310 a3e7a0c3479024bd6a0335c0aceeeef3 136 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.0E-37 T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03310 a3e7a0c3479024bd6a0335c0aceeeef3 136 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.0E-37 T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03310 a3e7a0c3479024bd6a0335c0aceeeef3 136 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.0E-37 T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03310 a3e7a0c3479024bd6a0335c0aceeeef3 136 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 27.9 T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03310 a3e7a0c3479024bd6a0335c0aceeeef3 136 Gene3D G3DSA:1.10.1900.20 56 118 5.9E-27 T 11-11-2016 TW_RS03310 a3e7a0c3479024bd6a0335c0aceeeef3 136 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.4E-41 T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03310 a3e7a0c3479024bd6a0335c0aceeeef3 136 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 11-11-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00850 ecb8743073d470b09472fd47c4bec689 616 Gene3D G3DSA:3.40.50.10490 249 445 5.8E-67 T 11-11-2016 TW_RS00850 ecb8743073d470b09472fd47c4bec689 616 Pfam PF13522 Glutamine amidotransferase domain 68 187 3.4E-21 T 11-11-2016 TW_RS00850 ecb8743073d470b09472fd47c4bec689 616 SUPERFAMILY SSF56235 2 239 6.18E-68 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TW_RS00850 ecb8743073d470b09472fd47c4bec689 616 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 616 38.032 T 11-11-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TW_RS00850 ecb8743073d470b09472fd47c4bec689 616 Pfam PF01380 SIS domain 466 597 1.2E-21 T 11-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 TW_RS00850 ecb8743073d470b09472fd47c4bec689 616 Pfam PF01380 SIS domain 297 420 4.5E-27 T 11-11-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 TW_RS00850 ecb8743073d470b09472fd47c4bec689 616 Gene3D G3DSA:3.60.20.10 2 243 8.5E-73 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TW_RS00850 ecb8743073d470b09472fd47c4bec689 616 Gene3D G3DSA:3.40.50.10490 446 616 2.0E-57 T 11-11-2016 TW_RS00850 ecb8743073d470b09472fd47c4bec689 616 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 616 2.0E-226 T 11-11-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TW_RS00850 ecb8743073d470b09472fd47c4bec689 616 SUPERFAMILY SSF53697 251 616 4.92E-97 T 11-11-2016 TW_RS01685 a841606ea18aa44c500290bab236c9d7 316 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 26 111 5.2E-15 T 11-11-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TW_RS01685 a841606ea18aa44c500290bab236c9d7 316 Pfam PF00589 Phage integrase family 133 301 4.7E-36 T 11-11-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TW_RS01685 a841606ea18aa44c500290bab236c9d7 316 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 24 316 52.722 T 11-11-2016 IPR023009 Tyrosine recombinase XerC/XerD TW_RS01685 a841606ea18aa44c500290bab236c9d7 316 SUPERFAMILY SSF56349 28 306 1.03E-46 T 11-11-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TW_RS01685 a841606ea18aa44c500290bab236c9d7 316 Gene3D G3DSA:1.10.443.10 134 306 1.0E-43 T 11-11-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 TW_RS01685 a841606ea18aa44c500290bab236c9d7 316 Gene3D G3DSA:1.10.150.130 25 120 3.6E-20 T 11-11-2016 IPR023109 Integrase/recombinase, N-terminal TW_RS00170 3f18c15b9c643d99aef013590848051b 207 SUPERFAMILY SSF51182 2 193 3.88E-63 T 11-11-2016 IPR011051 RmlC-like cupin domain TW_RS00170 3f18c15b9c643d99aef013590848051b 207 Gene3D G3DSA:2.60.120.10 3 191 1.2E-61 T 11-11-2016 IPR014710 RmlC-like jelly roll fold TW_RS00170 3f18c15b9c643d99aef013590848051b 207 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 180 1.0E-101 T 11-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TW_RS00170 3f18c15b9c643d99aef013590848051b 207 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 5.5E-54 T 11-11-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TW_RS01515 51181a621af3d508decf67d0ac856cc3 437 Gene3D G3DSA:1.10.3120.10 219 315 1.7E-11 T 11-11-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 TW_RS01515 51181a621af3d508decf67d0ac856cc3 437 Gene3D G3DSA:3.30.70.1050 7 123 2.6E-29 T 11-11-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 TW_RS01515 51181a621af3d508decf67d0ac856cc3 437 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 327 402 1.5E-4 T 11-11-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 TW_RS01515 51181a621af3d508decf67d0ac856cc3 437 Hamap MF_00303 Trigger factor [tig]. 5 411 14.131 T 11-11-2016 IPR005215 Trigger factor GO:0015031 TW_RS01515 51181a621af3d508decf67d0ac856cc3 437 SUPERFAMILY SSF54534 139 260 5.65E-11 T 11-11-2016 TW_RS01515 51181a621af3d508decf67d0ac856cc3 437 SUPERFAMILY SSF109998 262 420 2.75E-18 T 11-11-2016 IPR027304 Trigger factor/SurA domain TW_RS01515 51181a621af3d508decf67d0ac856cc3 437 Gene3D G3DSA:3.10.50.40 175 218 0.001 T 11-11-2016 TW_RS01515 51181a621af3d508decf67d0ac856cc3 437 SUPERFAMILY SSF102735 6 134 4.58E-29 T 11-11-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 TW_RS01515 51181a621af3d508decf67d0ac856cc3 437 TIGRFAM TIGR00115 tig: trigger factor 16 403 8.0E-68 T 11-11-2016 IPR005215 Trigger factor GO:0015031 TW_RS01515 51181a621af3d508decf67d0ac856cc3 437 Pfam PF05697 Bacterial trigger factor protein (TF) 10 148 1.5E-33 T 11-11-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 TW_RS00655 45c5d04a8d2347ac52fe7dca7bf0ce91 78 SUPERFAMILY SSF143800 2 77 7.26E-25 T 11-11-2016 TW_RS00655 45c5d04a8d2347ac52fe7dca7bf0ce91 78 Pfam PF00830 Ribosomal L28 family 4 61 2.6E-22 T 11-11-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00655 45c5d04a8d2347ac52fe7dca7bf0ce91 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 17.868 T 11-11-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS00655 45c5d04a8d2347ac52fe7dca7bf0ce91 78 Gene3D G3DSA:2.30.170.40 2 77 1.5E-29 T 11-11-2016 TW_RS00655 45c5d04a8d2347ac52fe7dca7bf0ce91 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 57 4.9E-20 T 11-11-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 SUPERFAMILY SSF50249 337 419 5.65E-24 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 SMART SM00532 7 468 1.1E-152 T 11-11-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 SUPERFAMILY SSF56091 8 335 1.64E-87 T 11-11-2016 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 16 621 1.2E-154 T 11-11-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 SUPERFAMILY SSF47781 423 623 1.33E-40 T 11-11-2016 IPR010994 RuvA domain 2-like TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 119 148 - T 11-11-2016 IPR018239 NAD-dependent DNA ligase, active site TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 Hamap MF_01588 DNA ligase [ligA]. 6 626 43.754 T 11-11-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 Gene3D G3DSA:3.30.470.30 124 232 3.5E-32 T 11-11-2016 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 Gene3D G3DSA:1.10.150.20 547 623 1.7E-21 T 11-11-2016 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 10 336 1.1E-81 T 11-11-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 350 365 - T 11-11-2016 IPR033136 NAD-dependent DNA ligase, conserved site TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 PIRSF PIRSF001604 1 628 3.7E-198 T 11-11-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 427 452 2.1E-5 T 11-11-2016 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 Gene3D G3DSA:3.30.1490.70 258 341 4.3E-31 T 11-11-2016 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 Gene3D G3DSA:1.10.150.20 455 545 7.2E-4 T 11-11-2016 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 Pfam PF12826 Helix-hairpin-helix motif 553 616 3.3E-19 T 11-11-2016 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 Gene3D G3DSA:1.10.287.610 8 68 9.9E-10 T 11-11-2016 TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 Gene3D G3DSA:2.40.50.140 342 407 1.6E-27 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01880 25d7ad865de7fba29f1f128881a234c2 628 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 341 417 1.9E-29 T 11-11-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 TW_RS03940 89d41229e56d67cc504f7177dcabc8ba 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 3 37 - T 11-11-2016 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03940 89d41229e56d67cc504f7177dcabc8ba 166 Pfam PF00466 Ribosomal protein L10 3 94 2.6E-21 T 11-11-2016 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TW_RS03940 89d41229e56d67cc504f7177dcabc8ba 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 155 18.154 T 11-11-2016 IPR022973 Ribosomal protein L10 TW_RS03940 89d41229e56d67cc504f7177dcabc8ba 166 SUPERFAMILY SSF160369 3 160 2.88E-37 T 11-11-2016 TW_RS02200 45089dfc36b333d1d02f2b9b05638c23 219 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 30 44 - T 11-11-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TW_RS02200 45089dfc36b333d1d02f2b9b05638c23 219 SUPERFAMILY SSF51366 1 212 8.14E-54 T 11-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TW_RS02200 45089dfc36b333d1d02f2b9b05638c23 219 Gene3D G3DSA:3.20.20.70 2 215 5.7E-72 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS02200 45089dfc36b333d1d02f2b9b05638c23 219 PIRSF PIRSF001461 1 219 2.0E-72 T 11-11-2016 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TW_RS02200 45089dfc36b333d1d02f2b9b05638c23 219 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 196 3.9E-60 T 11-11-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TW_RS01435 fca635ac8e49829c7a151888cbb55aec 386 Pfam PF01168 Alanine racemase, N-terminal domain 16 246 4.5E-39 T 11-11-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TW_RS01435 fca635ac8e49829c7a151888cbb55aec 386 Gene3D G3DSA:3.20.20.10 19 241 1.3E-40 T 11-11-2016 IPR029066 PLP-binding barrel TW_RS01435 fca635ac8e49829c7a151888cbb55aec 386 SMART SM01005 254 385 3.6E-6 T 11-11-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TW_RS01435 fca635ac8e49829c7a151888cbb55aec 386 SUPERFAMILY SSF51419 16 260 2.43E-35 T 11-11-2016 IPR029066 PLP-binding barrel TW_RS01435 fca635ac8e49829c7a151888cbb55aec 386 Hamap MF_01201 Alanine racemase. 9 385 14.363 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TW_RS01435 fca635ac8e49829c7a151888cbb55aec 386 PRINTS PR00992 Alanine racemase signature 34 50 3.7E-13 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TW_RS01435 fca635ac8e49829c7a151888cbb55aec 386 PRINTS PR00992 Alanine racemase signature 220 247 3.7E-13 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TW_RS01435 fca635ac8e49829c7a151888cbb55aec 386 PRINTS PR00992 Alanine racemase signature 141 153 3.7E-13 T 11-11-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TW_RS02125 96a6f2b8d42a054393c5616b2f3efd34 400 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 11-11-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TW_RS02125 96a6f2b8d42a054393c5616b2f3efd34 400 Pfam PF01264 Chorismate synthase 2 368 4.4E-112 T 11-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TW_RS02125 96a6f2b8d42a054393c5616b2f3efd34 400 SUPERFAMILY SSF103263 1 390 3.79E-131 T 11-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TW_RS02125 96a6f2b8d42a054393c5616b2f3efd34 400 TIGRFAM TIGR00033 aroC: chorismate synthase 2 372 1.1E-118 T 11-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TW_RS02125 96a6f2b8d42a054393c5616b2f3efd34 400 Hamap MF_00300 Chorismate synthase [aroC]. 2 375 33.162 T 11-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TW_RS02125 96a6f2b8d42a054393c5616b2f3efd34 400 Gene3D G3DSA:3.60.150.10 1 393 8.9E-139 T 11-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TW_RS02125 96a6f2b8d42a054393c5616b2f3efd34 400 PIRSF PIRSF001456 1 385 9.2E-119 T 11-11-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TW_RS02125 96a6f2b8d42a054393c5616b2f3efd34 400 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 11-11-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TW_RS00440 a6ed0f36d3e26e3edae17a44e50ffb99 145 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 87 134 9.9E-9 T 11-11-2016 IPR023845 Domain of unknown function DUF3817, transmembrane TW_RS00440 a6ed0f36d3e26e3edae17a44e50ffb99 145 Pfam PF12823 Domain of unknown function (DUF3817) 27 134 9.2E-21 T 11-11-2016 IPR023845 Domain of unknown function DUF3817, transmembrane TW_RS00610 fd8863d678bb73765db19ace42179934 153 Gene3D G3DSA:3.40.5.10 3 48 6.5E-20 T 11-11-2016 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00610 fd8863d678bb73765db19ace42179934 153 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 2 153 24.509 T 11-11-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS00610 fd8863d678bb73765db19ace42179934 153 Pfam PF01281 Ribosomal protein L9, N-terminal domain 4 47 3.3E-19 T 11-11-2016 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00610 fd8863d678bb73765db19ace42179934 153 TIGRFAM TIGR00158 L9: ribosomal protein bL9 3 153 5.9E-36 T 11-11-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS00610 fd8863d678bb73765db19ace42179934 153 SUPERFAMILY SSF55653 58 153 5.62E-24 T 11-11-2016 IPR020069 Ribosomal protein L9, C-terminal TW_RS00610 fd8863d678bb73765db19ace42179934 153 Gene3D G3DSA:3.10.430.100 63 153 7.8E-27 T 11-11-2016 IPR020069 Ribosomal protein L9, C-terminal TW_RS00610 fd8863d678bb73765db19ace42179934 153 ProSitePatterns PS00651 Ribosomal protein L9 signature. 14 41 - T 11-11-2016 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00610 fd8863d678bb73765db19ace42179934 153 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 151 9.4E-27 T 11-11-2016 IPR020069 Ribosomal protein L9, C-terminal TW_RS00610 fd8863d678bb73765db19ace42179934 153 SUPERFAMILY SSF55658 3 57 4.53E-16 T 11-11-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal TW_RS01560 48edf23c2847f213b80cd5da1b6f5207 136 SUPERFAMILY SSF54919 2 136 1.44E-48 T 11-11-2016 TW_RS01560 48edf23c2847f213b80cd5da1b6f5207 136 SMART SM00562 1 136 5.4E-55 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TW_RS01560 48edf23c2847f213b80cd5da1b6f5207 136 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 116 124 - T 11-11-2016 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TW_RS01560 48edf23c2847f213b80cd5da1b6f5207 136 Gene3D G3DSA:3.30.70.141 2 136 1.8E-50 T 11-11-2016 TW_RS01560 48edf23c2847f213b80cd5da1b6f5207 136 Pfam PF00334 Nucleoside diphosphate kinase 2 136 4.5E-47 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TW_RS01560 48edf23c2847f213b80cd5da1b6f5207 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 7.9E-31 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TW_RS01560 48edf23c2847f213b80cd5da1b6f5207 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 7.9E-31 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TW_RS01560 48edf23c2847f213b80cd5da1b6f5207 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 7.9E-31 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TW_RS01560 48edf23c2847f213b80cd5da1b6f5207 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 116 135 7.9E-31 T 11-11-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 SUPERFAMILY SSF56042 224 450 8.07E-48 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 760 267.615 T 11-11-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 SUPERFAMILY SSF55326 38 218 6.73E-46 T 11-11-2016 TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 PIRSF PIRSF001587 18 760 1.5E-304 T 11-11-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 38 751 3.2E-242 T 11-11-2016 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 Pfam PF00586 AIR synthase related protein, N-terminal domain 111 213 2.2E-23 T 11-11-2016 IPR016188 PurM-like, N-terminal domain TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 Pfam PF00586 AIR synthase related protein, N-terminal domain 464 581 2.6E-24 T 11-11-2016 IPR016188 PurM-like, N-terminal domain TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 Pfam PF02769 AIR synthase related protein, C-terminal domain 226 380 4.1E-30 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 Pfam PF02769 AIR synthase related protein, C-terminal domain 628 734 6.3E-11 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 SUPERFAMILY SSF56042 592 757 1.5E-29 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 SUPERFAMILY SSF55326 423 589 3.27E-53 T 11-11-2016 TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 Gene3D G3DSA:3.30.1330.10 438 583 1.2E-54 T 11-11-2016 IPR016188 PurM-like, N-terminal domain TW_RS04365 a8652d08a4c65fa4d2dedfa1b5d74ded 760 Gene3D G3DSA:3.30.1330.10 70 218 5.8E-47 T 11-11-2016 IPR016188 PurM-like, N-terminal domain TW_RS02210 6738395deaa48bf2c82d13f137d7cd1b 356 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 37 350 2.2E-66 T 11-11-2016 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 TW_RS02210 6738395deaa48bf2c82d13f137d7cd1b 356 PIRSF PIRSF002756 4 353 3.9E-118 T 11-11-2016 IPR005673 ABC transporter, phosphate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 TW_RS02210 6738395deaa48bf2c82d13f137d7cd1b 356 Gene3D G3DSA:3.40.190.10 130 290 1.4E-48 T 11-11-2016 TW_RS02210 6738395deaa48bf2c82d13f137d7cd1b 356 Pfam PF12849 PBP superfamily domain 28 320 3.8E-50 T 11-11-2016 IPR024370 PBP domain TW_RS02210 6738395deaa48bf2c82d13f137d7cd1b 356 Gene3D G3DSA:3.40.190.10 6 129 6.1E-11 T 11-11-2016 TW_RS02210 6738395deaa48bf2c82d13f137d7cd1b 356 Gene3D G3DSA:3.40.190.10 294 340 6.1E-11 T 11-11-2016 TW_RS02210 6738395deaa48bf2c82d13f137d7cd1b 356 SUPERFAMILY SSF53850 35 351 2.2E-73 T 11-11-2016 TW_RS04160 d201328a5b534ae049b614ec4d9e189f 432 Gene3D G3DSA:2.40.50.140 5 103 1.1E-15 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS04160 d201328a5b534ae049b614ec4d9e189f 432 SUPERFAMILY SSF55681 112 419 7.92E-77 T 11-11-2016 TW_RS04160 d201328a5b534ae049b614ec4d9e189f 432 Pfam PF00152 tRNA synthetases class II (D, K and N) 114 422 1.0E-75 T 11-11-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS04160 d201328a5b534ae049b614ec4d9e189f 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 387 401 3.4E-19 T 11-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS04160 d201328a5b534ae049b614ec4d9e189f 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 200 213 3.4E-19 T 11-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS04160 d201328a5b534ae049b614ec4d9e189f 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 347 363 3.4E-19 T 11-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS04160 d201328a5b534ae049b614ec4d9e189f 432 PRINTS PR01042 Aspartyl-tRNA synthetase signature 183 195 3.4E-19 T 11-11-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS04160 d201328a5b534ae049b614ec4d9e189f 432 Pfam PF01336 OB-fold nucleic acid binding domain 18 94 1.6E-8 T 11-11-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TW_RS04160 d201328a5b534ae049b614ec4d9e189f 432 SUPERFAMILY SSF50249 3 103 3.21E-13 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS04160 d201328a5b534ae049b614ec4d9e189f 432 Gene3D G3DSA:3.30.930.10 109 425 1.3E-87 T 11-11-2016 TW_RS03925 900656050360788c3556e637cf32637a 198 SMART SM00493 79 164 1.4E-16 T 11-11-2016 IPR006171 Toprim domain TW_RS03925 900656050360788c3556e637cf32637a 198 Pfam PF02132 RecR protein 39 77 2.9E-16 T 11-11-2016 IPR023628 Recombination protein RecR, C4-type zinc finger TW_RS03925 900656050360788c3556e637cf32637a 198 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 11-11-2016 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 TW_RS03925 900656050360788c3556e637cf32637a 198 SUPERFAMILY SSF111304 2 197 2.35E-74 T 11-11-2016 IPR023627 Recombination protein RecR TW_RS03925 900656050360788c3556e637cf32637a 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 4.4E-81 T 11-11-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TW_RS03925 900656050360788c3556e637cf32637a 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 102.746 T 11-11-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TW_RS03925 900656050360788c3556e637cf32637a 198 Pfam PF13662 Toprim domain 80 170 7.1E-25 T 11-11-2016 IPR006171 Toprim domain TW_RS03925 900656050360788c3556e637cf32637a 198 Gene3D G3DSA:3.40.50.140 115 166 1.7E-5 T 11-11-2016 IPR006171 Toprim domain TW_RS03530 5115fecdcdf7e356e5f412392a90d472 358 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 251 324 2.6E-6 T 11-11-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 TW_RS03530 5115fecdcdf7e356e5f412392a90d472 358 SUPERFAMILY SSF50156 157 250 6.44E-10 T 11-11-2016 IPR001478 PDZ domain GO:0005515 TW_RS03530 5115fecdcdf7e356e5f412392a90d472 358 Gene3D G3DSA:3.30.230.10 241 342 7.5E-16 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TW_RS03530 5115fecdcdf7e356e5f412392a90d472 358 SUPERFAMILY SSF54211 235 343 3.45E-16 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS03530 5115fecdcdf7e356e5f412392a90d472 358 Gene3D G3DSA:2.30.42.10 147 216 4.1E-8 T 11-11-2016 IPR001478 PDZ domain GO:0005515 TW_RS01760 807face8d51baae2348c0cd5a62deacf 350 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 313 4.1E-69 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TW_RS01760 807face8d51baae2348c0cd5a62deacf 350 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 51 64 - T 11-11-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TW_RS01760 807face8d51baae2348c0cd5a62deacf 350 Gene3D G3DSA:3.40.50.1100 59 143 5.3E-41 T 11-11-2016 TW_RS01760 807face8d51baae2348c0cd5a62deacf 350 PIRSF PIRSF038945 1 340 2.1E-141 T 11-11-2016 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 TW_RS01760 807face8d51baae2348c0cd5a62deacf 350 SUPERFAMILY SSF53686 2 332 1.31E-95 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TW_RS01760 807face8d51baae2348c0cd5a62deacf 350 Gene3D G3DSA:3.40.50.1100 144 321 5.1E-38 T 11-11-2016 TW_RS01760 807face8d51baae2348c0cd5a62deacf 350 TIGRFAM TIGR00260 thrC: threonine synthase 10 319 2.8E-80 T 11-11-2016 IPR004450 Threonine synthase-like TW_RS00765 d5e28ab41464d8983636ae3b841b3f1e 533 SUPERFAMILY SSF53850 28 529 9.41E-83 T 11-11-2016 TW_RS00765 d5e28ab41464d8983636ae3b841b3f1e 533 Gene3D G3DSA:3.90.76.10 48 197 4.8E-30 T 11-11-2016 TW_RS00765 d5e28ab41464d8983636ae3b841b3f1e 533 Gene3D G3DSA:3.10.105.10 317 502 2.0E-33 T 11-11-2016 TW_RS00765 d5e28ab41464d8983636ae3b841b3f1e 533 PIRSF PIRSF002741 27 532 3.0E-55 T 11-11-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TW_RS00765 d5e28ab41464d8983636ae3b841b3f1e 533 Gene3D G3DSA:3.40.190.10 198 316 7.5E-20 T 11-11-2016 TW_RS00765 d5e28ab41464d8983636ae3b841b3f1e 533 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 455 1.7E-44 T 11-11-2016 IPR000914 Solute-binding protein family 5 domain TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 SUPERFAMILY SSF56719 417 654 1.1E-74 T 11-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR00418 DNA topoisomerase II family signature 527 544 1.1E-59 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR00418 DNA topoisomerase II family signature 36 51 1.1E-59 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR00418 DNA topoisomerase II family signature 547 559 1.1E-59 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR00418 DNA topoisomerase II family signature 594 610 1.1E-59 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR00418 DNA topoisomerase II family signature 71 84 1.1E-59 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR00418 DNA topoisomerase II family signature 114 128 1.1E-59 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR00418 DNA topoisomerase II family signature 288 301 1.1E-59 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR00418 DNA topoisomerase II family signature 443 457 1.1E-59 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR00418 DNA topoisomerase II family signature 509 525 1.1E-59 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 175 5.9E-18 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 Pfam PF00204 DNA gyrase B 222 413 3.3E-53 T 11-11-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 SUPERFAMILY SSF55874 7 211 2.23E-54 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 Gene3D G3DSA:3.40.50.670 427 643 6.7E-74 T 11-11-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 Gene3D G3DSA:3.30.230.10 221 414 4.9E-45 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 SMART SM00387 32 177 7.3E-20 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 Gene3D G3DSA:3.30.565.10 7 215 5.9E-74 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 SMART SM00433 36 655 1.8E-237 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR01159 DNA gyrase subunit B signature 182 197 2.6E-31 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR01159 DNA gyrase subunit B signature 7 17 2.6E-31 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR01159 DNA gyrase subunit B signature 197 210 2.6E-31 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR01159 DNA gyrase subunit B signature 493 502 2.6E-31 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR01159 DNA gyrase subunit B signature 397 417 2.6E-31 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR01159 DNA gyrase subunit B signature 631 647 2.6E-31 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR01159 DNA gyrase subunit B signature 615 627 2.6E-31 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR01159 DNA gyrase subunit B signature 221 243 2.6E-31 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 PRINTS PR01159 DNA gyrase subunit B signature 333 349 2.6E-31 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 594 650 6.2E-25 T 11-11-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 ProSitePatterns PS00177 DNA topoisomerase II signature. 445 453 - T 11-11-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 Pfam PF01751 Toprim domain 442 543 1.9E-14 T 11-11-2016 IPR006171 Toprim domain TW_RS01445 1cac23e53650fde4a5750363912f6c2c 662 SUPERFAMILY SSF54211 270 413 3.03E-36 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS02990 3b67a7753c002eda63035d9a1eaf5583 361 PIRSF PIRSF006468 3 360 1.9E-123 T 11-11-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 TW_RS02990 3b67a7753c002eda63035d9a1eaf5583 361 SUPERFAMILY SSF56752 11 356 9.94E-97 T 11-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 TW_RS02990 3b67a7753c002eda63035d9a1eaf5583 361 Gene3D G3DSA:3.20.10.10 181 344 4.6E-59 T 11-11-2016 TW_RS02990 3b67a7753c002eda63035d9a1eaf5583 361 Pfam PF01063 Amino-transferase class IV 74 317 6.1E-30 T 11-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 TW_RS02990 3b67a7753c002eda63035d9a1eaf5583 361 ProSitePatterns PS00770 Aminotransferases class-IV signature. 236 266 - T 11-11-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 TW_RS02990 3b67a7753c002eda63035d9a1eaf5583 361 Gene3D G3DSA:3.30.470.10 15 180 1.5E-50 T 11-11-2016 TW_RS02990 3b67a7753c002eda63035d9a1eaf5583 361 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 48 357 9.7E-102 T 11-11-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: R-HSA-70895 TW_RS03815 69b61a7014130c891c03d94e25743192 371 SUPERFAMILY SSF53927 15 144 4.52E-28 T 11-11-2016 IPR016193 Cytidine deaminase-like GO:0003824 TW_RS03815 69b61a7014130c891c03d94e25743192 371 Gene3D G3DSA:3.40.430.10 134 234 3.7E-23 T 11-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 TW_RS03815 69b61a7014130c891c03d94e25743192 371 Gene3D G3DSA:3.40.430.10 266 349 4.0E-20 T 11-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 TW_RS03815 69b61a7014130c891c03d94e25743192 371 Pfam PF01872 RibD C-terminal domain 153 345 1.4E-34 T 11-11-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TW_RS03815 69b61a7014130c891c03d94e25743192 371 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 59 98 - T 11-11-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TW_RS03815 69b61a7014130c891c03d94e25743192 371 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 16 346 6.6E-64 T 11-11-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 TW_RS03815 69b61a7014130c891c03d94e25743192 371 Gene3D G3DSA:3.40.140.10 15 133 2.7E-22 T 11-11-2016 TW_RS03815 69b61a7014130c891c03d94e25743192 371 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 15 109 5.4E-13 T 11-11-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 TW_RS03815 69b61a7014130c891c03d94e25743192 371 SUPERFAMILY SSF53597 151 349 2.1E-42 T 11-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 TW_RS03815 69b61a7014130c891c03d94e25743192 371 PIRSF PIRSF006769 7 354 2.2E-111 T 11-11-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 TW_RS01085 50e64db7e5f8681b5cd15a93e6e3f059 176 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 4 176 25.392 T 11-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 TW_RS01085 50e64db7e5f8681b5cd15a93e6e3f059 176 Pfam PF01467 Cytidylyltransferase-like 8 151 2.2E-13 T 11-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TW_RS01085 50e64db7e5f8681b5cd15a93e6e3f059 176 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 60 1.2E-13 T 11-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TW_RS01085 50e64db7e5f8681b5cd15a93e6e3f059 176 SUPERFAMILY SSF52374 3 174 9.38E-32 T 11-11-2016 TW_RS01085 50e64db7e5f8681b5cd15a93e6e3f059 176 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 22 43 1.5E-13 T 11-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 TW_RS01085 50e64db7e5f8681b5cd15a93e6e3f059 176 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 4 22 1.5E-13 T 11-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 TW_RS01085 50e64db7e5f8681b5cd15a93e6e3f059 176 Gene3D G3DSA:3.40.50.620 1 174 1.3E-42 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS01085 50e64db7e5f8681b5cd15a93e6e3f059 176 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 5 169 1.2E-38 T 11-11-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3 TW_RS04065 83d86f2616345db0542b89dedfb57480 350 Gene3D G3DSA:3.20.20.210 2 348 6.5E-119 T 11-11-2016 TW_RS04065 83d86f2616345db0542b89dedfb57480 350 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 132 148 - T 11-11-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TW_RS04065 83d86f2616345db0542b89dedfb57480 350 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 13 22 - T 11-11-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TW_RS04065 83d86f2616345db0542b89dedfb57480 350 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 2 348 4.7E-102 T 11-11-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TW_RS04065 83d86f2616345db0542b89dedfb57480 350 SUPERFAMILY SSF51726 2 348 1.01E-87 T 11-11-2016 TW_RS04065 83d86f2616345db0542b89dedfb57480 350 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 2 348 5.6E-108 T 11-11-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TW_RS01575 db6a907116179057afcceccf8abdef53 82 Pfam PF01016 Ribosomal L27 protein 2 80 1.1E-35 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01575 db6a907116179057afcceccf8abdef53 82 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 11-11-2016 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01575 db6a907116179057afcceccf8abdef53 82 PRINTS PR00063 Ribosomal protein L27 signature 54 78 6.3E-35 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01575 db6a907116179057afcceccf8abdef53 82 PRINTS PR00063 Ribosomal protein L27 signature 29 53 6.3E-35 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01575 db6a907116179057afcceccf8abdef53 82 PRINTS PR00063 Ribosomal protein L27 signature 4 28 6.3E-35 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01575 db6a907116179057afcceccf8abdef53 82 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 82 24.951 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01575 db6a907116179057afcceccf8abdef53 82 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 80 3.0E-34 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01575 db6a907116179057afcceccf8abdef53 82 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 69 7.0E-18 T 11-11-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01575 db6a907116179057afcceccf8abdef53 82 SUPERFAMILY SSF110324 2 78 3.49E-31 T 11-11-2016 TW_RS01575 db6a907116179057afcceccf8abdef53 82 Gene3D G3DSA:2.40.50.100 20 79 2.3E-28 T 11-11-2016 TW_RS04315 4520f8c83c28e567b0b12908e197583b 426 Pfam PF13393 Histidyl-tRNA synthetase 8 340 1.5E-38 T 11-11-2016 TW_RS04315 4520f8c83c28e567b0b12908e197583b 426 Gene3D G3DSA:3.30.930.10 4 203 1.1E-68 T 11-11-2016 TW_RS04315 4520f8c83c28e567b0b12908e197583b 426 Gene3D G3DSA:3.30.930.10 263 346 1.1E-68 T 11-11-2016 TW_RS04315 4520f8c83c28e567b0b12908e197583b 426 SUPERFAMILY SSF55681 5 346 4.59E-64 T 11-11-2016 TW_RS04315 4520f8c83c28e567b0b12908e197583b 426 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 410 9.3E-89 T 11-11-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TW_RS04315 4520f8c83c28e567b0b12908e197583b 426 PIRSF PIRSF001549 1 410 1.9E-85 T 11-11-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TW_RS01650 be5f8cec4ad8d11641b115bac687ecdf 231 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 228 2.2E-73 T 11-11-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TW_RS01650 be5f8cec4ad8d11641b115bac687ecdf 231 PIRSF PIRSF000386 1 231 3.1E-84 T 11-11-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TW_RS01650 be5f8cec4ad8d11641b115bac687ecdf 231 Gene3D G3DSA:1.10.1270.20 159 225 8.6E-28 T 11-11-2016 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TW_RS01650 be5f8cec4ad8d11641b115bac687ecdf 231 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 231 86.377 T 11-11-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TW_RS01650 be5f8cec4ad8d11641b115bac687ecdf 231 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 219 1.2E-59 T 11-11-2016 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TW_RS01650 be5f8cec4ad8d11641b115bac687ecdf 231 Gene3D G3DSA:3.40.1280.10 1 158 2.8E-55 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TW_RS01650 be5f8cec4ad8d11641b115bac687ecdf 231 SUPERFAMILY SSF75217 1 228 2.49E-83 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases TW_RS01660 95ca937c3c90256799f90d5b33c845dc 230 SUPERFAMILY SSF51306 34 215 1.88E-48 T 11-11-2016 IPR015927 Peptidase S24/S26A/S26B/S26C TW_RS01660 95ca937c3c90256799f90d5b33c845dc 230 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 21 209 1.2E-39 T 11-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TW_RS01660 95ca937c3c90256799f90d5b33c845dc 230 ProSitePatterns PS00761 Signal peptidases I signature 3. 168 181 - T 11-11-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 TW_RS01660 95ca937c3c90256799f90d5b33c845dc 230 Pfam PF10502 Signal peptidase, peptidase S26 108 202 3.1E-8 T 11-11-2016 IPR019533 Peptidase S26 TW_RS01660 95ca937c3c90256799f90d5b33c845dc 230 Gene3D G3DSA:2.10.109.10 32 123 2.6E-41 T 11-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain TW_RS01660 95ca937c3c90256799f90d5b33c845dc 230 Gene3D G3DSA:2.10.109.10 163 217 2.6E-41 T 11-11-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain TW_RS01660 95ca937c3c90256799f90d5b33c845dc 230 Pfam PF00717 Peptidase S24-like 42 84 2.3E-9 T 11-11-2016 IPR019759 Peptidase S24/S26A/S26B TW_RS01660 95ca937c3c90256799f90d5b33c845dc 230 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 36 52 1.2E-21 T 11-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TW_RS01660 95ca937c3c90256799f90d5b33c845dc 230 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 113 125 1.2E-21 T 11-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TW_RS01660 95ca937c3c90256799f90d5b33c845dc 230 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 163 182 1.2E-21 T 11-11-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 389 454 1.4E-24 T 11-11-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 SMART SM00382 175 327 5.7E-6 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 SUPERFAMILY SSF52540 144 354 1.68E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 Gene3D G3DSA:1.10.1750.10 377 475 2.4E-30 T 11-11-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 11 473 5.0E-148 T 11-11-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 Gene3D G3DSA:3.40.50.300 138 306 4.1E-56 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 ProSitePatterns PS01008 DnaA protein signature. 436 454 - T 11-11-2016 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 Pfam PF00308 Bacterial dnaA protein 144 360 2.8E-91 T 11-11-2016 IPR013317 Chromosomal replication initiator protein DnaA TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 8 476 29.054 T 11-11-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 SMART SM00760 386 454 8.4E-34 T 11-11-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 176 196 4.5E-44 T 11-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 208 222 4.5E-44 T 11-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 240 254 4.5E-44 T 11-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 274 301 4.5E-44 T 11-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 435 454 4.5E-44 T 11-11-2016 IPR020591 Chromosomal replication control, initiator DnaA-like TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 SUPERFAMILY SSF48295 373 475 7.32E-30 T 11-11-2016 IPR010921 Trp repressor/replication initiator GO:0043565 TW_RS00005 5ec04d7d32dc5a9be75eae62cccdbbe0 478 Gene3D G3DSA:1.10.8.60 309 376 6.4E-25 T 11-11-2016 TW_RS04100 d035c3401de55978b04c7f51fb9734fc 249 Gene3D G3DSA:3.40.50.1000 169 246 7.7E-37 T 11-11-2016 IPR023214 HAD-like domain TW_RS04100 d035c3401de55978b04c7f51fb9734fc 249 Gene3D G3DSA:3.40.50.1000 1 66 7.7E-37 T 11-11-2016 IPR023214 HAD-like domain TW_RS04100 d035c3401de55978b04c7f51fb9734fc 249 Gene3D G3DSA:3.40.50.10410 67 168 3.9E-27 T 11-11-2016 IPR023215 Nitrophenylphosphatase-like domain TW_RS04100 d035c3401de55978b04c7f51fb9734fc 249 Pfam PF13344 Haloacid dehalogenase-like hydrolase 1 96 1.6E-20 T 11-11-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA TW_RS04100 d035c3401de55978b04c7f51fb9734fc 249 Pfam PF13242 HAD-hyrolase-like 169 240 7.5E-23 T 11-11-2016 TW_RS04100 d035c3401de55978b04c7f51fb9734fc 249 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 170 209 9.3E-6 T 11-11-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 TW_RS04100 d035c3401de55978b04c7f51fb9734fc 249 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 2 218 2.9E-40 T 11-11-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA TW_RS04100 d035c3401de55978b04c7f51fb9734fc 249 SUPERFAMILY SSF56784 1 240 8.7E-62 T 11-11-2016 IPR023214 HAD-like domain TW_RS04230 f99a5eae99223244b066f8fb80c794c4 688 Gene3D G3DSA:3.40.390.10 315 435 2.3E-101 T 11-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 TW_RS04230 f99a5eae99223244b066f8fb80c794c4 688 Gene3D G3DSA:3.40.390.10 474 688 2.3E-101 T 11-11-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 TW_RS04230 f99a5eae99223244b066f8fb80c794c4 688 Pfam PF05649 Peptidase family M13 37 432 2.7E-90 T 11-11-2016 IPR008753 Peptidase M13, N-terminal domain GO:0006508 TW_RS04230 f99a5eae99223244b066f8fb80c794c4 688 Pfam PF01431 Peptidase family M13 483 684 1.0E-68 T 11-11-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 TW_RS04230 f99a5eae99223244b066f8fb80c794c4 688 SUPERFAMILY SSF55486 33 688 8.79E-192 T 11-11-2016 TW_RS04230 f99a5eae99223244b066f8fb80c794c4 688 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 587 598 1.0E-21 T 11-11-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 TW_RS04230 f99a5eae99223244b066f8fb80c794c4 688 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 475 487 1.0E-21 T 11-11-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 TW_RS04230 f99a5eae99223244b066f8fb80c794c4 688 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 493 505 1.0E-21 T 11-11-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 TW_RS04230 f99a5eae99223244b066f8fb80c794c4 688 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 514 530 1.0E-21 T 11-11-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 SUPERFAMILY SSF52540 286 449 1.93E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 SUPERFAMILY SSF50447 690 787 2.08E-27 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 Gene3D G3DSA:2.40.30.10 690 787 2.8E-30 T 11-11-2016 TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 ProSitePatterns PS01176 Initiation factor 2 signature. 740 762 - T 11-11-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 Pfam PF11987 Translation-initiation factor 2 573 678 1.2E-35 T 11-11-2016 IPR023115 Translation initiation factor IF- 2, domain 3 TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 46 1.6E-6 T 11-11-2016 IPR006847 Translation initiation factor IF-2, N-terminal TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 199 250 5.2E-9 T 11-11-2016 IPR006847 Translation initiation factor IF-2, N-terminal TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 Pfam PF00009 Elongation factor Tu GTP binding domain 290 446 3.1E-34 T 11-11-2016 TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 Gene3D G3DSA:3.40.50.10050 587 666 1.1E-22 T 11-11-2016 IPR023115 Translation initiation factor IF- 2, domain 3 TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 1 787 16.436 T 11-11-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 195 786 6.7E-229 T 11-11-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 Gene3D G3DSA:2.40.30.10 457 551 2.1E-21 T 11-11-2016 TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 288 443 1.2E-29 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 Gene3D G3DSA:3.40.50.300 286 447 1.1E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 SUPERFAMILY SSF50447 458 541 2.29E-24 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain TW_RS03345 b5dfb963d0702f537bba51f2f027c080 788 SUPERFAMILY SSF52156 566 695 5.23E-35 T 11-11-2016 IPR023115 Translation initiation factor IF- 2, domain 3 TW_RS04335 a52df30e2565622486800d645192d783 440 Gene3D G3DSA:2.40.50.100 4 86 2.3E-19 T 11-11-2016 TW_RS04335 a52df30e2565622486800d645192d783 440 Gene3D G3DSA:3.30.559.10 212 438 5.7E-71 T 11-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 TW_RS04335 a52df30e2565622486800d645192d783 440 Pfam PF02817 e3 binding domain 170 204 1.0E-11 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 TW_RS04335 a52df30e2565622486800d645192d783 440 SUPERFAMILY SSF51230 4 89 1.2E-20 T 11-11-2016 IPR011053 Single hybrid motif TW_RS04335 a52df30e2565622486800d645192d783 440 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 212 438 5.1E-74 T 11-11-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 TW_RS04335 a52df30e2565622486800d645192d783 440 Pfam PF00364 Biotin-requiring enzyme 8 77 3.5E-15 T 11-11-2016 IPR000089 Biotin/lipoyl attachment TW_RS04335 a52df30e2565622486800d645192d783 440 SUPERFAMILY SSF52777 209 438 6.23E-71 T 11-11-2016 TW_RS04335 a52df30e2565622486800d645192d783 440 SUPERFAMILY SSF47005 167 207 3.01E-10 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 TW_RS04335 a52df30e2565622486800d645192d783 440 Gene3D G3DSA:4.10.320.10 167 211 3.9E-15 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 TW_RS03445 d284aa87df09e254192e026f9ec719b6 236 Pfam PF02511 Thymidylate synthase complementing protein 12 223 6.7E-50 T 11-11-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 TW_RS03445 d284aa87df09e254192e026f9ec719b6 236 Hamap MF_01408 Thymidylate synthase ThyX [thyX]. 1 236 27.918 T 11-11-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 TW_RS03445 d284aa87df09e254192e026f9ec719b6 236 SUPERFAMILY SSF69796 3 229 1.12E-54 T 11-11-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 TW_RS03445 d284aa87df09e254192e026f9ec719b6 236 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 11 228 2.6E-54 T 11-11-2016 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 TW_RS00430 2f4734158d734e13540a8775a6b3e0ef 373 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 293 2.9E-29 T 11-11-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TW_RS00430 2f4734158d734e13540a8775a6b3e0ef 373 Gene3D G3DSA:3.20.20.70 14 363 5.6E-62 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS00430 2f4734158d734e13540a8775a6b3e0ef 373 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 2 364 2.2E-150 T 11-11-2016 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 TW_RS00430 2f4734158d734e13540a8775a6b3e0ef 373 SMART SM01240 11 367 3.6E-13 T 11-11-2016 TW_RS00430 2f4734158d734e13540a8775a6b3e0ef 373 SUPERFAMILY SSF51412 110 367 4.71E-55 T 11-11-2016 TW_RS00430 2f4734158d734e13540a8775a6b3e0ef 373 SUPERFAMILY SSF51412 7 74 4.71E-55 T 11-11-2016 TW_RS02690 e70e24322844accca41c33849a29a16e 287 Gene3D G3DSA:3.20.20.70 189 278 4.1E-44 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS02690 e70e24322844accca41c33849a29a16e 287 Gene3D G3DSA:3.20.20.70 21 157 4.1E-44 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS02690 e70e24322844accca41c33849a29a16e 287 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 6 281 3.8E-137 T 11-11-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TW_RS02690 e70e24322844accca41c33849a29a16e 287 Pfam PF01680 SOR/SNZ family 5 209 5.0E-103 T 11-11-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TW_RS02690 e70e24322844accca41c33849a29a16e 287 ProSitePatterns PS01235 PdxS/SNZ family signature. 202 220 - T 11-11-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TW_RS02690 e70e24322844accca41c33849a29a16e 287 SUPERFAMILY SSF51366 15 266 2.87E-57 T 11-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TW_RS02690 e70e24322844accca41c33849a29a16e 287 PIRSF PIRSF029271 1 286 7.9E-144 T 11-11-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TW_RS02690 e70e24322844accca41c33849a29a16e 287 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 1 287 47.359 T 11-11-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TW_RS02095 0edb2e34abfca84e69b291760b65caf7 205 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 204 28.153 T 11-11-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TW_RS02095 0edb2e34abfca84e69b291760b65caf7 205 Gene3D G3DSA:3.10.290.10 97 176 2.7E-21 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 TW_RS02095 0edb2e34abfca84e69b291760b65caf7 205 SUPERFAMILY SSF55174 6 202 1.7E-52 T 11-11-2016 TW_RS02095 0edb2e34abfca84e69b291760b65caf7 205 SMART SM01390 5 90 1.6E-30 T 11-11-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TW_RS02095 0edb2e34abfca84e69b291760b65caf7 205 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 11-11-2016 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS02095 0edb2e34abfca84e69b291760b65caf7 205 Gene3D G3DSA:1.10.1050.10 6 96 5.0E-28 T 11-11-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TW_RS02095 0edb2e34abfca84e69b291760b65caf7 205 SMART SM00363 91 151 2.8E-14 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 TW_RS02095 0edb2e34abfca84e69b291760b65caf7 205 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 5 90 1.5E-19 T 11-11-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TW_RS02095 0edb2e34abfca84e69b291760b65caf7 205 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 5 203 3.1E-59 T 11-11-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TW_RS02095 0edb2e34abfca84e69b291760b65caf7 205 Pfam PF01479 S4 domain 91 138 1.5E-15 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 TW_RS01040 0cf81ec86f668a8fe48ce1238652addd 108 Pfam PF00037 4Fe-4S binding domain 34 56 5.4E-9 T 11-11-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TW_RS01040 0cf81ec86f668a8fe48ce1238652addd 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 11-11-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TW_RS01040 0cf81ec86f668a8fe48ce1238652addd 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.5E-16 T 11-11-2016 IPR000813 7Fe ferredoxin GO:0009055 TW_RS01040 0cf81ec86f668a8fe48ce1238652addd 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.5E-16 T 11-11-2016 IPR000813 7Fe ferredoxin GO:0009055 TW_RS01040 0cf81ec86f668a8fe48ce1238652addd 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.5E-16 T 11-11-2016 IPR000813 7Fe ferredoxin GO:0009055 TW_RS01040 0cf81ec86f668a8fe48ce1238652addd 108 Gene3D G3DSA:3.30.70.20 7 72 4.6E-18 T 11-11-2016 TW_RS01040 0cf81ec86f668a8fe48ce1238652addd 108 SUPERFAMILY SSF54862 3 95 4.85E-21 T 11-11-2016 TW_RS02920 097ea335fbb292b3e9c9f8cf317c8c1b 142 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 137 8.4E-36 T 11-11-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TW_RS02920 097ea335fbb292b3e9c9f8cf317c8c1b 142 Pfam PF02381 MraZ protein, putative antitoxin-like 71 136 7.7E-17 T 11-11-2016 IPR020603 MraZ domain TW_RS02920 097ea335fbb292b3e9c9f8cf317c8c1b 142 Pfam PF02381 MraZ protein, putative antitoxin-like 2 69 7.5E-12 T 11-11-2016 IPR020603 MraZ domain TW_RS02920 097ea335fbb292b3e9c9f8cf317c8c1b 142 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 142 42.335 T 11-11-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TW_RS02920 097ea335fbb292b3e9c9f8cf317c8c1b 142 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 137 1.0E-75 T 11-11-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TW_RS02920 097ea335fbb292b3e9c9f8cf317c8c1b 142 SUPERFAMILY SSF89447 2 135 3.66E-39 T 11-11-2016 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 11-11-2016 IPR031157 Tr-type G domain, conserved site TW_RS03755 b333ca482a74694b1adad643bb51b287 701 Gene3D G3DSA:3.40.50.300 7 293 1.1E-106 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03755 b333ca482a74694b1adad643bb51b287 701 SUPERFAMILY SSF50447 271 408 3.53E-32 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain TW_RS03755 b333ca482a74694b1adad643bb51b287 701 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 182 1.2E-38 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 Gene3D G3DSA:3.30.70.240 606 692 2.8E-33 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain TW_RS03755 b333ca482a74694b1adad643bb51b287 701 Pfam PF00679 Elongation factor G C-terminus 608 693 2.7E-30 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain TW_RS03755 b333ca482a74694b1adad643bb51b287 701 Pfam PF14492 Elongation Factor G, domain II 408 481 1.8E-33 T 11-11-2016 IPR009022 Elongation factor G, III-V domain TW_RS03755 b333ca482a74694b1adad643bb51b287 701 SUPERFAMILY SSF54980 406 484 4.32E-24 T 11-11-2016 IPR009022 Elongation factor G, III-V domain TW_RS03755 b333ca482a74694b1adad643bb51b287 701 SUPERFAMILY SSF54211 483 606 7.59E-40 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS03755 b333ca482a74694b1adad643bb51b287 701 SUPERFAMILY SSF54980 610 697 5.04E-30 T 11-11-2016 IPR009022 Elongation factor G, III-V domain TW_RS03755 b333ca482a74694b1adad643bb51b287 701 Pfam PF03144 Elongation factor Tu domain 2 328 395 4.9E-12 T 11-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 PRINTS PR00315 GTP-binding elongation factor signature 60 68 1.9E-16 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 PRINTS PR00315 GTP-binding elongation factor signature 80 90 1.9E-16 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 PRINTS PR00315 GTP-binding elongation factor signature 132 141 1.9E-16 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.9E-16 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 PRINTS PR00315 GTP-binding elongation factor signature 96 107 1.9E-16 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 Gene3D G3DSA:2.40.30.10 309 408 1.8E-33 T 11-11-2016 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 SMART SM00838 607 694 3.4E-56 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain TW_RS03755 b333ca482a74694b1adad643bb51b287 701 TIGRFAM TIGR00484 EF-G: translation elongation factor G 8 698 0.0 T 11-11-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 Hamap MF_00054_B Elongation factor G [fusA]. 8 698 106.566 T 11-11-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 Pfam PF03764 Elongation factor G, domain IV 483 604 7.6E-47 T 11-11-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 SMART SM00889 484 605 7.2E-70 T 11-11-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 Pfam PF00009 Elongation factor Tu GTP binding domain 11 288 8.1E-68 T 11-11-2016 TW_RS03755 b333ca482a74694b1adad643bb51b287 701 SUPERFAMILY SSF52540 8 288 1.96E-106 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03755 b333ca482a74694b1adad643bb51b287 701 Gene3D G3DSA:3.30.230.10 488 605 1.0E-45 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TW_RS03755 b333ca482a74694b1adad643bb51b287 701 Gene3D G3DSA:3.30.70.870 409 484 1.2E-37 T 11-11-2016 TW_RS02305 194858527f24e14e09ac3058e6eff34a 266 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 1 259 1.1E-80 T 11-11-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 TW_RS02305 194858527f24e14e09ac3058e6eff34a 266 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 1 261 15.88 T 11-11-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 TW_RS02305 194858527f24e14e09ac3058e6eff34a 266 Pfam PF01040 UbiA prenyltransferase family 1 241 1.1E-60 T 11-11-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 TW_RS02305 194858527f24e14e09ac3058e6eff34a 266 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 32 54 - T 11-11-2016 IPR030470 UbiA prenyltransferase conserved site TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 Pfam PF02780 Transketolase, C-terminal domain 509 614 4.0E-14 T 11-11-2016 IPR033248 Transketolase, C-terminal domain TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 Gene3D G3DSA:3.40.50.920 510 620 2.6E-16 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 9 623 36.539 T 11-11-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 12 621 1.4E-161 T 11-11-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 SUPERFAMILY SSF52518 302 487 4.42E-53 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 SUPERFAMILY SSF52922 503 623 1.83E-21 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 ProSitePatterns PS00801 Transketolase signature 1. 35 54 - T 11-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 Gene3D G3DSA:3.40.50.970 227 308 7.8E-40 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 Gene3D G3DSA:3.40.50.970 9 181 7.8E-40 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 Gene3D G3DSA:3.40.50.970 309 487 3.3E-55 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 SMART SM00861 326 490 1.2E-53 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 10 286 5.5E-98 T 11-11-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 Pfam PF02779 Transketolase, pyrimidine binding domain 327 487 3.4E-35 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 SUPERFAMILY SSF52518 246 373 2.62E-60 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 SUPERFAMILY SSF52518 27 200 2.62E-60 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS01500 6bd7534ab796f271f9e1faba00da7241 629 ProSitePatterns PS00802 Transketolase signature 2. 432 448 - T 11-11-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TW_RS00465 b68f75336fa0a4fe2fcda9ad398bc200 208 SUPERFAMILY SSF53328 1 190 2.35E-53 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TW_RS00465 b68f75336fa0a4fe2fcda9ad398bc200 208 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 2 186 25.711 T 11-11-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 TW_RS00465 b68f75336fa0a4fe2fcda9ad398bc200 208 Pfam PF00551 Formyl transferase 1 180 4.4E-44 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TW_RS00465 b68f75336fa0a4fe2fcda9ad398bc200 208 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 1 187 2.8E-53 T 11-11-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 TW_RS00465 b68f75336fa0a4fe2fcda9ad398bc200 208 Gene3D G3DSA:3.40.50.170 2 188 1.2E-57 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 SUPERFAMILY SSF55424 341 445 6.01E-14 T 11-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 Gene3D G3DSA:3.50.50.60 258 331 5.2E-41 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 Gene3D G3DSA:3.50.50.60 3 129 5.2E-41 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 2.6E-38 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 251 265 2.6E-38 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 394 409 2.6E-38 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 2.6E-38 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.6E-38 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 2.6E-38 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 2.6E-38 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 2.6E-38 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 Gene3D G3DSA:3.30.390.30 333 447 1.2E-14 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 SUPERFAMILY SSF51905 99 354 9.43E-34 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 SUPERFAMILY SSF51905 3 53 9.43E-34 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 312 4.3E-35 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 442 9.3E-8 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.9E-15 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.9E-15 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 1.9E-15 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 266 1.9E-15 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 1.9E-15 T 11-11-2016 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 Gene3D G3DSA:3.50.50.60 130 256 2.4E-22 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS03535 6e60ee9b3b9e0b7112c0e3b0251d8253 452 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 11-11-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TW_RS01360 9f77515609390a686740a7bdc9fa0910 1160 Pfam PF02811 PHP domain 5 189 2.8E-49 T 11-11-2016 IPR004013 PHP domain GO:0003824 TW_RS01360 9f77515609390a686740a7bdc9fa0910 1160 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 1036 0.0 T 11-11-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TW_RS01360 9f77515609390a686740a7bdc9fa0910 1160 Pfam PF14579 Helix-hairpin-helix motif 822 908 2.6E-23 T 11-11-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TW_RS01360 9f77515609390a686740a7bdc9fa0910 1160 Gene3D G3DSA:1.10.150.280 847 879 5.9E-4 T 11-11-2016 TW_RS01360 9f77515609390a686740a7bdc9fa0910 1160 SMART SM00481 4 71 1.3E-28 T 11-11-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 TW_RS01360 9f77515609390a686740a7bdc9fa0910 1160 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 308 747 9.6E-161 T 11-11-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TW_RS01360 9f77515609390a686740a7bdc9fa0910 1160 SUPERFAMILY SSF89550 3 89 1.59E-31 T 11-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TW_RS01360 9f77515609390a686740a7bdc9fa0910 1160 SUPERFAMILY SSF89550 116 279 1.59E-31 T 11-11-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TW_RS01360 9f77515609390a686740a7bdc9fa0910 1160 Pfam PF01336 OB-fold nucleic acid binding domain 1000 1076 2.8E-10 T 11-11-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TW_RS01360 9f77515609390a686740a7bdc9fa0910 1160 Gene3D G3DSA:3.20.20.140 1 273 7.0E-47 T 11-11-2016 TW_RS03775 562b41b48d3efa779701c25c3fc17596 121 Pfam PF14155 Domain of unknown function (DUF4307) 18 115 2.5E-11 T 11-11-2016 IPR025443 Protein of unknown function DUF4307 TW_RS02995 8bec499742e46320e79e7ab337f0b357 333 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 188 331 2.4E-60 T 11-11-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TW_RS02995 8bec499742e46320e79e7ab337f0b357 333 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 19 182 1.6E-71 T 11-11-2016 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TW_RS02995 8bec499742e46320e79e7ab337f0b357 333 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 6 333 42.447 T 11-11-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TW_RS02995 8bec499742e46320e79e7ab337f0b357 333 SUPERFAMILY SSF48179 188 331 7.14E-63 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TW_RS02995 8bec499742e46320e79e7ab337f0b357 333 SUPERFAMILY SSF51735 7 187 1.82E-65 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS02995 8bec499742e46320e79e7ab337f0b357 333 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 20 333 4.4E-122 T 11-11-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TW_RS02995 8bec499742e46320e79e7ab337f0b357 333 Gene3D G3DSA:1.10.1040.10 34 329 7.3E-102 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TW_RS03920 a36b4f3191ff626a1364424d0e8d1a59 418 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 11-11-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 TW_RS03920 a36b4f3191ff626a1364424d0e8d1a59 418 SUPERFAMILY SSF55021 330 405 1.83E-17 T 11-11-2016 TW_RS03920 a36b4f3191ff626a1364424d0e8d1a59 418 SUPERFAMILY SSF53633 4 243 6.68E-69 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase TW_RS03920 a36b4f3191ff626a1364424d0e8d1a59 418 SUPERFAMILY SSF55021 247 326 1.88E-12 T 11-11-2016 TW_RS03920 a36b4f3191ff626a1364424d0e8d1a59 418 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 62 403 2.4E-103 T 11-11-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 TW_RS03920 a36b4f3191ff626a1364424d0e8d1a59 418 Gene3D G3DSA:3.40.1160.10 3 245 2.8E-64 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase TW_RS03920 a36b4f3191ff626a1364424d0e8d1a59 418 PIRSF PIRSF000726 54 411 1.9E-110 T 11-11-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 TW_RS03920 a36b4f3191ff626a1364424d0e8d1a59 418 Pfam PF00696 Amino acid kinase family 3 229 3.5E-52 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase TW_RS00825 a356bff5548f39c621f6341a4ccbd102 141 Gene3D G3DSA:3.90.1180.10 3 130 1.4E-55 T 11-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TW_RS00825 a356bff5548f39c621f6341a4ccbd102 141 ProSitePatterns PS00783 Ribosomal protein L13 signature. 96 118 - T 11-11-2016 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 TW_RS00825 a356bff5548f39c621f6341a4ccbd102 141 PIRSF PIRSF002181 1 140 4.2E-49 T 11-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TW_RS00825 a356bff5548f39c621f6341a4ccbd102 141 Pfam PF00572 Ribosomal protein L13 5 128 4.7E-53 T 11-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TW_RS00825 a356bff5548f39c621f6341a4ccbd102 141 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 6 137 27.904 T 11-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TW_RS00825 a356bff5548f39c621f6341a4ccbd102 141 SUPERFAMILY SSF52161 3 131 1.14E-52 T 11-11-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TW_RS00825 a356bff5548f39c621f6341a4ccbd102 141 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 3 131 1.5E-57 T 11-11-2016 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 SUPERFAMILY SSF52935 320 467 3.53E-34 T 11-11-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 Pfam PF02887 Pyruvate kinase, alpha/beta domain 353 465 5.0E-27 T 11-11-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 PRINTS PR01050 Pyruvate kinase family signature 214 240 6.9E-64 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 PRINTS PR01050 Pyruvate kinase family signature 266 290 6.9E-64 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 PRINTS PR01050 Pyruvate kinase family signature 241 265 6.9E-64 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 PRINTS PR01050 Pyruvate kinase family signature 184 198 6.9E-64 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 PRINTS PR01050 Pyruvate kinase family signature 291 309 6.9E-64 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 PRINTS PR01050 Pyruvate kinase family signature 310 326 6.9E-64 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 PRINTS PR01050 Pyruvate kinase family signature 59 75 6.9E-64 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 11-11-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 SUPERFAMILY SSF50800 70 164 8.02E-24 T 11-11-2016 IPR011037 Pyruvate kinase-like, insert domain TW_RS02560 b669a46d83273d8c70abd260091edef1 471 SUPERFAMILY SSF51621 1 75 5.14E-91 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 SUPERFAMILY SSF51621 165 335 5.14E-91 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 Gene3D G3DSA:3.20.20.60 2 72 1.5E-93 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 Gene3D G3DSA:3.20.20.60 167 323 1.5E-93 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 Gene3D G3DSA:2.40.33.10 73 166 2.7E-24 T 11-11-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 Gene3D G3DSA:3.40.1380.20 324 467 2.2E-35 T 11-11-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 Pfam PF00224 Pyruvate kinase, barrel domain 1 335 1.1E-113 T 11-11-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02560 b669a46d83273d8c70abd260091edef1 471 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 466 9.8E-152 T 11-11-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 SUPERFAMILY SSF54980 296 375 2.34E-17 T 11-11-2016 IPR009022 Elongation factor G, III-V domain TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 PRINTS PR00315 GTP-binding elongation factor signature 12 25 6.9E-13 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 PRINTS PR00315 GTP-binding elongation factor signature 55 63 6.9E-13 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 PRINTS PR00315 GTP-binding elongation factor signature 79 89 6.9E-13 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 PRINTS PR00315 GTP-binding elongation factor signature 131 140 6.9E-13 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 PRINTS PR00315 GTP-binding elongation factor signature 95 106 6.9E-13 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 Gene3D G3DSA:3.30.70.870 296 374 1.2E-22 T 11-11-2016 TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 48 63 - T 11-11-2016 IPR031157 Tr-type G domain, conserved site TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 Gene3D G3DSA:3.40.50.300 7 199 6.0E-57 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 Pfam PF00679 Elongation factor G C-terminus 403 490 1.6E-19 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 SUPERFAMILY SSF52540 6 235 2.42E-53 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 TIGRFAM TIGR01393 lepA: elongation factor 4 9 598 5.2E-272 T 11-11-2016 IPR006297 Elongation factor 4 GO:0005525 TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 Pfam PF06421 GTP-binding protein LepA C-terminus 493 597 1.2E-45 T 11-11-2016 IPR013842 GTP-binding protein LepA, C-terminal TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 Pfam PF03144 Elongation factor Tu domain 2 210 280 7.6E-8 T 11-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 181 1.1E-18 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 Hamap MF_00071 Elongation factor 4 [lepA]. 1 601 257.073 T 11-11-2016 IPR006297 Elongation factor 4 GO:0005525 TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 SUPERFAMILY SSF54980 403 498 3.12E-22 T 11-11-2016 IPR009022 Elongation factor G, III-V domain TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 Pfam PF00009 Elongation factor Tu GTP binding domain 9 186 5.5E-50 T 11-11-2016 TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 Gene3D G3DSA:3.30.70.240 405 493 2.9E-19 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 SMART SM00838 402 486 0.0013 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain TW_RS02630 2da755410f0777e4cc69dfd8b03d3611 601 Gene3D G3DSA:2.40.30.10 200 294 4.9E-19 T 11-11-2016 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 Gene3D G3DSA:3.40.50.1370 72 211 1.8E-43 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 74 216 1.1E-36 T 11-11-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 SUPERFAMILY SSF53671 72 382 6.15E-75 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 228 378 6.9E-25 T 11-11-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 PRINTS PR00101 Aspartate carbamoyltransferase signature 149 158 3.6E-28 T 11-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 PRINTS PR00101 Aspartate carbamoyltransferase signature 362 376 3.6E-28 T 11-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 PRINTS PR00101 Aspartate carbamoyltransferase signature 109 131 3.6E-28 T 11-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 PRINTS PR00101 Aspartate carbamoyltransferase signature 203 220 3.6E-28 T 11-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 PRINTS PR00101 Aspartate carbamoyltransferase signature 299 308 3.6E-28 T 11-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 74 381 4.2E-83 T 11-11-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 119 126 - T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 Gene3D G3DSA:3.40.50.1370 212 368 2.1E-36 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 204 215 1.4E-15 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 119 138 1.4E-15 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 346 369 1.4E-15 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TW_RS03105 1da4001a3dde73d47df0b9ec932dac5d 406 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 331 340 1.4E-15 T 11-11-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 182 317 2.2E-38 T 11-11-2016 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 Gene3D G3DSA:1.10.1040.10 186 318 9.6E-39 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 8 320 29.924 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 12 29 7.5E-34 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 175 199 7.5E-34 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 135 155 7.5E-34 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 200 224 7.5E-34 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 240 257 7.5E-34 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 190 211 - T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 SUPERFAMILY SSF48179 181 321 2.72E-39 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 PIRSF PIRSF000114 2 325 9.1E-99 T 11-11-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 SUPERFAMILY SSF51735 8 182 2.51E-41 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 Gene3D G3DSA:3.40.50.720 8 185 2.4E-52 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS01385 7cac580210cf5c84767ab529c9c990cc 325 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 9 161 3.1E-41 T 11-11-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166|Reactome: R-HSA-75109 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 Pfam PF13365 Trypsin-like peptidase domain 138 284 5.0E-32 T 11-11-2016 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 Gene3D G3DSA:2.30.42.10 329 415 1.2E-23 T 11-11-2016 IPR001478 PDZ domain GO:0005515 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 SMART SM00228 326 402 1.3E-15 T 11-11-2016 IPR001478 PDZ domain GO:0005515 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 PRINTS PR00834 HtrA/DegQ protease family signature 213 237 1.4E-39 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 PRINTS PR00834 HtrA/DegQ protease family signature 277 294 1.4E-39 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 PRINTS PR00834 HtrA/DegQ protease family signature 360 372 1.4E-39 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 PRINTS PR00834 HtrA/DegQ protease family signature 173 193 1.4E-39 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 PRINTS PR00834 HtrA/DegQ protease family signature 255 272 1.4E-39 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 PRINTS PR00834 HtrA/DegQ protease family signature 147 159 1.4E-39 T 11-11-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 Pfam PF13180 PDZ domain 326 411 3.2E-15 T 11-11-2016 IPR001478 PDZ domain GO:0005515 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 SUPERFAMILY SSF50156 297 415 1.97E-22 T 11-11-2016 IPR001478 PDZ domain GO:0005515 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 SUPERFAMILY SSF50494 114 318 1.79E-50 T 11-11-2016 IPR009003 Peptidase S1, PA clan TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 Gene3D G3DSA:2.40.10.10 207 328 3.7E-38 T 11-11-2016 TW_RS03515 6f8a50394027b5a21a073ad0d1684274 420 Gene3D G3DSA:2.40.10.10 113 206 1.3E-22 T 11-11-2016 TW_RS00130 fa704526d1eaa9166405aada31d3073d 525 SUPERFAMILY SSF52096 13 261 2.57E-75 T 11-11-2016 IPR029045 ClpP/crotonase-like domain TW_RS00130 fa704526d1eaa9166405aada31d3073d 525 Gene3D G3DSA:3.90.226.10 22 261 1.5E-77 T 11-11-2016 IPR029045 ClpP/crotonase-like domain TW_RS00130 fa704526d1eaa9166405aada31d3073d 525 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 100 114 8.9E-6 T 11-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 TW_RS00130 fa704526d1eaa9166405aada31d3073d 525 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 134 152 8.9E-6 T 11-11-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388 TW_RS00130 fa704526d1eaa9166405aada31d3073d 525 Pfam PF01039 Carboxyl transferase domain 33 523 6.2E-189 T 11-11-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS00130 fa704526d1eaa9166405aada31d3073d 525 Gene3D G3DSA:3.90.226.10 274 525 2.1E-90 T 11-11-2016 IPR029045 ClpP/crotonase-like domain TW_RS00130 fa704526d1eaa9166405aada31d3073d 525 SUPERFAMILY SSF52096 230 525 5.62E-84 T 11-11-2016 IPR029045 ClpP/crotonase-like domain TW_RS03615 daea5ddc3c253aa9a4d350e3d03c2d21 121 Gene3D G3DSA:1.10.287.1040 52 109 1.2E-14 T 11-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TW_RS03615 daea5ddc3c253aa9a4d350e3d03c2d21 121 SUPERFAMILY SSF116842 52 105 5.36E-14 T 11-11-2016 TW_RS03615 daea5ddc3c253aa9a4d350e3d03c2d21 121 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 53 104 5.6E-16 T 11-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TW_RS03615 daea5ddc3c253aa9a4d350e3d03c2d21 121 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 53 113 11.674 T 11-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TW_RS03615 daea5ddc3c253aa9a4d350e3d03c2d21 121 Pfam PF02609 Exonuclease VII small subunit 54 103 5.5E-14 T 11-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TW_RS03615 daea5ddc3c253aa9a4d350e3d03c2d21 121 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 53 94 2.0E-17 T 11-11-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 TW_RS04325 b6e607e242addd48794f11b5d0e650c7 196 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 180 2.1E-69 T 11-11-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 TW_RS04325 b6e607e242addd48794f11b5d0e650c7 196 Gene3D G3DSA:2.70.40.10 1 183 6.9E-64 T 11-11-2016 IPR029054 dUTPase-like TW_RS04325 b6e607e242addd48794f11b5d0e650c7 196 Pfam PF00692 dUTPase 68 180 5.7E-9 T 11-11-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 TW_RS04325 b6e607e242addd48794f11b5d0e650c7 196 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 182 33.057 T 11-11-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 TW_RS04325 b6e607e242addd48794f11b5d0e650c7 196 SUPERFAMILY SSF51283 1 183 4.97E-54 T 11-11-2016 IPR029054 dUTPase-like TW_RS03915 99cbefbc5880e35e5255ee57ab27174a 337 SUPERFAMILY SSF51735 2 152 1.69E-42 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS03915 99cbefbc5880e35e5255ee57ab27174a 337 Gene3D G3DSA:3.40.50.720 3 138 2.3E-50 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS03915 99cbefbc5880e35e5255ee57ab27174a 337 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 135 320 1.1E-42 T 11-11-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TW_RS03915 99cbefbc5880e35e5255ee57ab27174a 337 SUPERFAMILY SSF55347 125 321 1.55E-58 T 11-11-2016 TW_RS03915 99cbefbc5880e35e5255ee57ab27174a 337 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 235 249 - T 11-11-2016 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 TW_RS03915 99cbefbc5880e35e5255ee57ab27174a 337 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 4 333 4.0E-116 T 11-11-2016 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 TW_RS03915 99cbefbc5880e35e5255ee57ab27174a 337 PIRSF PIRSF000148 1 337 8.8E-108 T 11-11-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 TW_RS03915 99cbefbc5880e35e5255ee57ab27174a 337 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 115 8.7E-28 T 11-11-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TW_RS03915 99cbefbc5880e35e5255ee57ab27174a 337 SMART SM00859 3 116 4.5E-34 T 11-11-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TW_RS03915 99cbefbc5880e35e5255ee57ab27174a 337 Gene3D G3DSA:3.30.360.10 139 316 7.4E-64 T 11-11-2016 TW_RS01775 77d395e761278152f4804dbd8afe6998 347 SMART SM00937 61 174 2.5E-37 T 11-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 TW_RS01775 77d395e761278152f4804dbd8afe6998 347 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 224 240 - T 11-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TW_RS01775 77d395e761278152f4804dbd8afe6998 347 Pfam PF00472 RF-1 domain 210 317 1.7E-40 T 11-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TW_RS01775 77d395e761278152f4804dbd8afe6998 347 SUPERFAMILY SSF75620 25 343 9.81E-112 T 11-11-2016 TW_RS01775 77d395e761278152f4804dbd8afe6998 347 Pfam PF03462 PCRF domain 13 199 2.1E-52 T 11-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 TW_RS01775 77d395e761278152f4804dbd8afe6998 347 Gene3D G3DSA:3.30.160.20 208 281 3.9E-33 T 11-11-2016 IPR014720 Double-stranded RNA-binding domain TW_RS01995 23330084833e2d93a24e0472a515a7b9 391 Pfam PF00570 HRDC domain 223 291 6.6E-12 T 11-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 TW_RS01995 23330084833e2d93a24e0472a515a7b9 391 Gene3D G3DSA:3.30.420.10 18 188 5.4E-9 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TW_RS01995 23330084833e2d93a24e0472a515a7b9 391 SUPERFAMILY SSF53098 18 210 1.41E-46 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TW_RS01995 23330084833e2d93a24e0472a515a7b9 391 SMART SM00341 220 301 0.0011 T 11-11-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 TW_RS01995 23330084833e2d93a24e0472a515a7b9 391 SMART SM00474 16 183 4.7E-18 T 11-11-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TW_RS01995 23330084833e2d93a24e0472a515a7b9 391 Pfam PF01612 3'-5' exonuclease 19 182 1.2E-26 T 11-11-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TW_RS01995 23330084833e2d93a24e0472a515a7b9 391 SUPERFAMILY SSF47819 217 305 7.48E-12 T 11-11-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:1.20.1270.10 509 578 7.3E-15 T 11-11-2016 IPR029048 Heat shock protein 70kD, C-terminal domain Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 313 327 - T 11-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 578 4.1E-269 T 11-11-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:3.30.30.30 39 100 5.3E-19 T 11-11-2016 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 Pfam PF00012 Hsp70 protein 4 79 5.5E-30 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 Pfam PF00012 Hsp70 protein 82 578 6.3E-207 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 SUPERFAMILY SSF53067 163 358 1.97E-62 T 11-11-2016 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 11-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 11-11-2016 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 364 383 1.1E-73 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 174 184 1.1E-73 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.1E-73 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 341 361 1.1E-73 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.1E-73 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.1E-73 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 445 461 1.1E-73 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 114 134 1.1E-73 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 PRINTS PR00301 70kDa heat shock protein signature 310 326 1.1E-73 T 11-11-2016 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:3.90.640.10 206 291 1.9E-29 T 11-11-2016 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:3.30.420.40 4 38 6.4E-58 T 11-11-2016 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:3.30.420.40 101 166 6.4E-58 T 11-11-2016 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:3.30.420.40 295 337 3.4E-28 T 11-11-2016 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:3.30.420.40 167 205 3.4E-28 T 11-11-2016 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 Gene3D G3DSA:2.60.34.10 366 508 3.3E-73 T 11-11-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 SUPERFAMILY SSF53067 1 159 2.73E-59 T 11-11-2016 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 597 35.483 T 11-11-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453 TW_RS04140 90fe05b864ef639d000bb9b21893282b 603 SUPERFAMILY SSF100920 360 516 2.49E-62 T 11-11-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 TW_RS04015 35a69c15916e9985249b429828e9fbf3 263 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 260 1.4E-56 T 11-11-2016 IPR023214 HAD-like domain TW_RS04015 35a69c15916e9985249b429828e9fbf3 263 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 11-11-2016 IPR000150 Cof protein GO:0016787 TW_RS04015 35a69c15916e9985249b429828e9fbf3 263 Gene3D G3DSA:3.40.50.1000 1 78 6.7E-31 T 11-11-2016 IPR023214 HAD-like domain TW_RS04015 35a69c15916e9985249b429828e9fbf3 263 Gene3D G3DSA:3.40.50.1000 165 262 6.7E-31 T 11-11-2016 IPR023214 HAD-like domain TW_RS04015 35a69c15916e9985249b429828e9fbf3 263 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 225 1.1E-18 T 11-11-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 TW_RS04015 35a69c15916e9985249b429828e9fbf3 263 SUPERFAMILY SSF56784 1 263 2.6E-44 T 11-11-2016 IPR023214 HAD-like domain TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 SUPERFAMILY SSF52540 922 1127 3.77E-42 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 560 1213 7.4E-269 T 11-11-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 Pfam PF00271 Helicase conserved C-terminal domain 951 1049 9.4E-12 T 11-11-2016 IPR001650 Helicase, C-terminal TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 SUPERFAMILY SSF143517 1134 1218 3.27E-25 T 11-11-2016 TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 SMART SM01058 614 716 1.5E-33 T 11-11-2016 IPR003711 CarD-like/TRCF domain TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 SMART SM00490 966 1050 3.6E-13 T 11-11-2016 IPR001650 Helicase, C-terminal TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 SUPERFAMILY SSF52540 62 138 1.46E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 SUPERFAMILY SSF52540 168 272 1.46E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 SMART SM00982 1140 1244 4.3E-29 T 11-11-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 Pfam PF02559 CarD-like/TRCF domain 615 715 4.1E-26 T 11-11-2016 IPR003711 CarD-like/TRCF domain TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 Gene3D G3DSA:3.40.50.300 727 924 1.7E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 SUPERFAMILY SSF141259 608 684 3.01E-13 T 11-11-2016 IPR003711 CarD-like/TRCF domain TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 Gene3D G3DSA:3.40.50.300 925 1102 1.5E-31 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 Pfam PF00270 DEAD/DEAH box helicase 747 906 1.7E-16 T 11-11-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 Pfam PF03461 TRCF domain 1141 1217 1.3E-22 T 11-11-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 72 1234 26.864 T 11-11-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 SUPERFAMILY SSF52540 665 923 1.32E-55 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 SMART SM00487 740 930 1.5E-31 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TW_RS03220 1398e60678fb805f10e12a9798c17354 1291 Gene3D G3DSA:3.30.2060.10 198 270 1.2E-11 T 11-11-2016 TW_RS02340 c1aa0d504528f8a8ccd9ba45f835398d 285 Pfam PF02104 SURF1 family 30 242 2.1E-23 T 11-11-2016 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS03860 26c4ab208972b587e829b2a73fbd6d28 199 SUPERFAMILY SSF52540 1 194 7.72E-41 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03860 26c4ab208972b587e829b2a73fbd6d28 199 Hamap MF_00165 Thymidylate kinase [tmk]. 1 193 26.234 T 11-11-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TW_RS03860 26c4ab208972b587e829b2a73fbd6d28 199 Gene3D G3DSA:3.40.50.300 1 193 9.0E-55 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03860 26c4ab208972b587e829b2a73fbd6d28 199 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 185 8.3E-41 T 11-11-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TW_RS03860 26c4ab208972b587e829b2a73fbd6d28 199 Pfam PF02223 Thymidylate kinase 5 185 1.8E-38 T 11-11-2016 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 Gene3D G3DSA:1.20.58.180 211 286 6.6E-25 T 11-11-2016 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 SUPERFAMILY SSF55681 7 285 8.7E-111 T 11-11-2016 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 246 262 1.2E-53 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 60 75 1.2E-53 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 161 176 1.2E-53 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 138 158 1.2E-53 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 81 101 1.2E-53 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 112 136 1.2E-53 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 318 1017 4.0E-121 T 11-11-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 8 284 3.1E-126 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 Gene3D G3DSA:3.30.930.10 4 208 1.8E-84 T 11-11-2016 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 8 286 9.8E-116 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 6 286 49.622 T 11-11-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 SUPERFAMILY SSF109604 673 815 2.01E-9 T 11-11-2016 TW_RS01415 2206b379dfa6b4bf87abbefdbacc52bb 1024 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 321 879 3.3E-137 T 11-11-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 TW_RS04195 f578a0721c972eb7e0658e2dbf6b426a 104 SUPERFAMILY SSF81345 13 81 2.48E-9 T 11-11-2016 IPR029022 ABC transporter, BtuC-like TW_RS04195 f578a0721c972eb7e0658e2dbf6b426a 104 Pfam PF00950 ABC 3 transport family 13 83 1.8E-17 T 11-11-2016 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TW_RS01645 b8476b09ef7cc8057c39b7ddf40f10a5 182 Gene3D G3DSA:2.40.30.60 3 94 1.9E-7 T 11-11-2016 IPR002676 RimM protein GO:0006364 TW_RS01645 b8476b09ef7cc8057c39b7ddf40f10a5 182 SUPERFAMILY SSF50346 106 172 2.04E-10 T 11-11-2016 IPR011033 PRC-barrel-like TW_RS01645 b8476b09ef7cc8057c39b7ddf40f10a5 182 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 161 2.4E-21 T 11-11-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TW_RS01645 b8476b09ef7cc8057c39b7ddf40f10a5 182 SUPERFAMILY SSF50447 3 94 5.3E-7 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain TW_RS01645 b8476b09ef7cc8057c39b7ddf40f10a5 182 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 173 15.26 T 11-11-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TW_RS01645 b8476b09ef7cc8057c39b7ddf40f10a5 182 Gene3D G3DSA:2.30.30.240 106 172 2.2E-10 T 11-11-2016 TW_RS01645 b8476b09ef7cc8057c39b7ddf40f10a5 182 Pfam PF01782 RimM N-terminal domain 5 95 2.6E-9 T 11-11-2016 IPR002676 RimM protein GO:0006364 TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 SUPERFAMILY SSF109604 21 205 1.07E-61 T 11-11-2016 TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 Pfam PF13291 ACT domain 658 733 1.0E-13 T 11-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 SUPERFAMILY SSF55021 657 733 4.16E-12 T 11-11-2016 TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 Gene3D G3DSA:3.30.460.10 193 339 4.8E-44 T 11-11-2016 TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 SUPERFAMILY SSF81301 207 369 8.99E-58 T 11-11-2016 TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 SMART SM00954 250 360 1.0E-63 T 11-11-2016 IPR007685 RelA/SpoT GO:0015969 TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 43 733 4.9E-224 T 11-11-2016 IPR004811 RelA/SpoT family GO:0015969 TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 SUPERFAMILY SSF81271 399 467 2.4E-18 T 11-11-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 Pfam PF04607 Region found in RelA / SpoT proteins 250 359 2.2E-35 T 11-11-2016 IPR007685 RelA/SpoT GO:0015969 TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 Gene3D G3DSA:3.10.20.30 408 470 1.7E-20 T 11-11-2016 IPR012675 Beta-grasp domain TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 Pfam PF02824 TGS domain 408 467 2.2E-20 T 11-11-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 SMART SM00471 58 168 5.0E-7 T 11-11-2016 IPR003607 HD/PDEase domain TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 Pfam PF13328 HD domain 43 190 3.0E-42 T 11-11-2016 IPR003607 HD/PDEase domain TW_RS02640 72c7e29eddc9c1b6ce0271b450dd98fa 734 Gene3D G3DSA:3.30.70.260 660 730 2.1E-12 T 11-11-2016 TW_RS02715 e51948067bb32ea75aaf191e6be8dca9 289 PRINTS PR00599 Methionine aminopeptidase-1 signature 129 145 9.6E-22 T 11-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase TW_RS02715 e51948067bb32ea75aaf191e6be8dca9 289 PRINTS PR00599 Methionine aminopeptidase-1 signature 199 211 9.6E-22 T 11-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase TW_RS02715 e51948067bb32ea75aaf191e6be8dca9 289 PRINTS PR00599 Methionine aminopeptidase-1 signature 231 243 9.6E-22 T 11-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase TW_RS02715 e51948067bb32ea75aaf191e6be8dca9 289 PRINTS PR00599 Methionine aminopeptidase-1 signature 107 120 9.6E-22 T 11-11-2016 IPR001714 Peptidase M24, methionine aminopeptidase TW_RS02715 e51948067bb32ea75aaf191e6be8dca9 289 Gene3D G3DSA:3.90.230.10 46 288 6.6E-90 T 11-11-2016 IPR000994 Peptidase M24, structural domain TW_RS02715 e51948067bb32ea75aaf191e6be8dca9 289 SUPERFAMILY SSF55920 17 288 3.53E-83 T 11-11-2016 IPR000994 Peptidase M24, structural domain TW_RS02715 e51948067bb32ea75aaf191e6be8dca9 289 Pfam PF00557 Metallopeptidase family M24 52 280 3.4E-50 T 11-11-2016 IPR000994 Peptidase M24, structural domain TW_RS02715 e51948067bb32ea75aaf191e6be8dca9 289 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 205 223 - T 11-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 TW_RS02715 e51948067bb32ea75aaf191e6be8dca9 289 Hamap MF_01974 Methionine aminopeptidase [map]. 42 289 39.42 T 11-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 TW_RS02715 e51948067bb32ea75aaf191e6be8dca9 289 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 44 288 1.3E-89 T 11-11-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 Gene3D G3DSA:3.30.1130.10 350 447 5.2E-25 T 11-11-2016 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 286 2.3E-84 T 11-11-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 Pfam PF00809 Pterin binding enzyme 17 273 2.1E-77 T 11-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 Gene3D G3DSA:3.30.70.560 495 588 1.5E-47 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 Gene3D G3DSA:3.30.70.560 637 700 1.5E-47 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 Gene3D G3DSA:3.20.20.20 13 288 4.1E-97 T 11-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 Pfam PF02152 Dihydroneopterin aldolase 350 446 3.1E-22 T 11-11-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 SUPERFAMILY SSF55083 494 584 5.62E-15 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 SMART SM00905 350 451 1.1E-26 T 11-11-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 11-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 SUPERFAMILY SSF51717 14 287 4.58E-86 T 11-11-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 SUPERFAMILY SSF55083 635 698 5.62E-14 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 497 585 2.7E-11 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 634 678 1.5E-7 T 11-11-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 TIGRFAM TIGR00526 folB_dom: FolB domain 349 447 2.2E-17 T 11-11-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 SUPERFAMILY SSF55620 349 447 3.0E-23 T 11-11-2016 TW_RS00990 667051eb21d3aafcbc50042bf200b682 765 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 11-11-2016 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TW_RS01170 da5b24dfa6650b66f99639f602c81b23 220 ProSitePatterns PS00548 Ribosomal protein S3 signature. 167 201 - T 11-11-2016 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01170 da5b24dfa6650b66f99639f602c81b23 220 Pfam PF00189 Ribosomal protein S3, C-terminal domain 124 206 5.4E-33 T 11-11-2016 TW_RS01170 da5b24dfa6650b66f99639f602c81b23 220 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 210 6.5E-85 T 11-11-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TW_RS01170 da5b24dfa6650b66f99639f602c81b23 220 Gene3D G3DSA:3.30.300.20 17 111 3.3E-30 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta TW_RS01170 da5b24dfa6650b66f99639f602c81b23 220 SUPERFAMILY SSF54821 111 209 2.09E-33 T 11-11-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01170 da5b24dfa6650b66f99639f602c81b23 220 SMART SM00322 64 129 8.6E-5 T 11-11-2016 IPR004087 K Homology domain GO:0003676 TW_RS01170 da5b24dfa6650b66f99639f602c81b23 220 Gene3D G3DSA:3.30.1140.32 112 209 1.0E-37 T 11-11-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01170 da5b24dfa6650b66f99639f602c81b23 220 SUPERFAMILY SSF54814 2 110 3.4E-34 T 11-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 TW_RS01170 da5b24dfa6650b66f99639f602c81b23 220 Pfam PF07650 KH domain 42 114 4.1E-19 T 11-11-2016 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01170 da5b24dfa6650b66f99639f602c81b23 220 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 215 36.352 T 11-11-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TW_RS03610 13c4d88945354d649f9d23e4ce27cfc3 404 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 18 403 19.064 T 11-11-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 TW_RS03610 13c4d88945354d649f9d23e4ce27cfc3 404 Pfam PF13742 OB-fold nucleic acid binding domain 22 106 3.7E-9 T 11-11-2016 IPR025824 OB-fold nucleic acid binding domain GO:0003676 TW_RS03610 13c4d88945354d649f9d23e4ce27cfc3 404 Pfam PF02601 Exonuclease VII, large subunit 338 400 7.5E-10 T 11-11-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 TW_RS03610 13c4d88945354d649f9d23e4ce27cfc3 404 Pfam PF02601 Exonuclease VII, large subunit 136 347 3.0E-52 T 11-11-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 TW_RS03610 13c4d88945354d649f9d23e4ce27cfc3 404 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 22 402 5.5E-100 T 11-11-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 11-11-2016 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 Pfam PF00344 SecY translocase 73 423 9.5E-109 T 11-11-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 439 27.812 T 11-11-2016 IPR026593 Protein translocase subunit SecY TW_RS01235 e68c08a407cf91478c4d01080a714517 441 PIRSF PIRSF004557 2 440 9.9E-111 T 11-11-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 374 392 6.1E-98 T 11-11-2016 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 113 136 6.1E-98 T 11-11-2016 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 272 291 6.1E-98 T 11-11-2016 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 6.1E-98 T 11-11-2016 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 72 92 6.1E-98 T 11-11-2016 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 6.1E-98 T 11-11-2016 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 6.1E-98 T 11-11-2016 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 319 341 6.1E-98 T 11-11-2016 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 408 426 6.1E-98 T 11-11-2016 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 SUPERFAMILY SSF103491 4 430 8.37E-115 T 11-11-2016 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 Gene3D G3DSA:1.10.3370.10 5 439 2.3E-138 T 11-11-2016 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 11-11-2016 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TW_RS01235 e68c08a407cf91478c4d01080a714517 441 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 435 5.9E-124 T 11-11-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 SUPERFAMILY SSF56719 403 644 8.37E-80 T 11-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 SMART SM00433 38 642 0.0 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 618 634 1.4E-60 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 369 383 1.4E-60 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 479 488 1.4E-60 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 602 614 1.4E-60 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 9 19 1.4E-60 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 183 198 1.4E-60 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 251 269 1.4E-60 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 383 403 1.4E-60 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 198 211 1.4E-60 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR01159 DNA gyrase subunit B signature 321 337 1.4E-60 T 11-11-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 495 511 3.8E-67 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 277 290 3.8E-67 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 513 530 3.8E-67 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 116 130 3.8E-67 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 429 443 3.8E-67 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 533 545 3.8E-67 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 581 597 3.8E-67 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 38 53 3.8E-67 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 PRINTS PR00418 DNA topoisomerase II family signature 73 86 3.8E-67 T 11-11-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 6 649 83.381 T 11-11-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 Gene3D G3DSA:3.40.50.670 413 630 1.4E-84 T 11-11-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 Pfam PF00204 DNA gyrase B 226 399 4.5E-57 T 11-11-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 Gene3D G3DSA:3.30.230.10 225 399 1.7E-65 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 SMART SM00387 34 178 2.6E-22 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 Gene3D G3DSA:3.30.565.10 9 216 1.4E-86 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 SUPERFAMILY SSF55874 9 214 3.8E-69 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 578 638 3.7E-26 T 11-11-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 Pfam PF01751 Toprim domain 428 536 3.1E-16 T 11-11-2016 IPR006171 Toprim domain TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 9 649 3.7E-279 T 11-11-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 36 177 3.5E-22 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 SUPERFAMILY SSF54211 226 399 2.09E-52 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS00025 6da93c1444a53ee620edfee1385439ae 649 ProSitePatterns PS00177 DNA topoisomerase II signature. 431 439 - T 11-11-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00615 c1f7a2edd14e99c033f8c4c930bdf69d 61 ProSitePatterns PS00057 Ribosomal protein S18 signature. 6 29 - T 11-11-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00615 c1f7a2edd14e99c033f8c4c930bdf69d 61 PRINTS PR00974 Ribosomal protein S18 family signature 13 23 3.0E-16 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00615 c1f7a2edd14e99c033f8c4c930bdf69d 61 PRINTS PR00974 Ribosomal protein S18 family signature 23 30 3.0E-16 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00615 c1f7a2edd14e99c033f8c4c930bdf69d 61 PRINTS PR00974 Ribosomal protein S18 family signature 31 45 3.0E-16 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00615 c1f7a2edd14e99c033f8c4c930bdf69d 61 PRINTS PR00974 Ribosomal protein S18 family signature 45 55 3.0E-16 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00615 c1f7a2edd14e99c033f8c4c930bdf69d 61 TIGRFAM TIGR00165 S18: ribosomal protein bS18 3 55 4.9E-21 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00615 c1f7a2edd14e99c033f8c4c930bdf69d 61 SUPERFAMILY SSF46911 3 56 7.19E-21 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00615 c1f7a2edd14e99c033f8c4c930bdf69d 61 Gene3D G3DSA:4.10.640.10 6 56 1.8E-23 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00615 c1f7a2edd14e99c033f8c4c930bdf69d 61 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 7 55 4.0E-11 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00615 c1f7a2edd14e99c033f8c4c930bdf69d 61 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 1 58 16.476 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00615 c1f7a2edd14e99c033f8c4c930bdf69d 61 Pfam PF01084 Ribosomal protein S18 4 52 6.6E-21 T 11-11-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 Pfam PF01131 DNA topoisomerase 139 567 1.3E-115 T 11-11-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 SMART SM00436 115 203 3.5E-46 T 11-11-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 Pfam PF01751 Toprim domain 4 124 1.4E-26 T 11-11-2016 IPR006171 Toprim domain TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 307 321 - T 11-11-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 SMART SM00437 270 530 5.5E-105 T 11-11-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 Gene3D G3DSA:2.70.20.10 340 475 1.8E-26 T 11-11-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 Gene3D G3DSA:2.70.20.10 195 335 1.7E-21 T 11-11-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 Pfam PF13368 Topoisomerase C-terminal repeat 776 825 1.1E-15 T 11-11-2016 IPR025589 Topoisomerase C-terminal repeat TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 Pfam PF13368 Topoisomerase C-terminal repeat 654 708 1.4E-12 T 11-11-2016 IPR025589 Topoisomerase C-terminal repeat TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 Pfam PF13368 Topoisomerase C-terminal repeat 715 764 1.3E-14 T 11-11-2016 IPR025589 Topoisomerase C-terminal repeat TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 Pfam PF13368 Topoisomerase C-terminal repeat 605 645 2.0E-5 T 11-11-2016 IPR025589 Topoisomerase C-terminal repeat TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 SUPERFAMILY SSF56712 1 571 2.22E-173 T 11-11-2016 IPR023405 DNA topoisomerase, type IA, core domain TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 173 191 1.5E-33 T 11-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 89 102 1.5E-33 T 11-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 493 507 1.5E-33 T 11-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 312 321 1.5E-33 T 11-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 391 407 1.5E-33 T 11-11-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 Gene3D G3DSA:3.40.50.140 1 145 1.7E-45 T 11-11-2016 IPR006171 Toprim domain TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 4 617 4.6E-218 T 11-11-2016 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 725 49.088 T 11-11-2016 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 Gene3D G3DSA:1.10.460.10 476 571 3.2E-49 T 11-11-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 Gene3D G3DSA:1.10.460.10 146 193 3.2E-49 T 11-11-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TW_RS03865 772b68773c6bd6ad2010058b6c0220c0 841 SMART SM00493 2 115 8.2E-29 T 11-11-2016 IPR006171 Toprim domain TW_RS01705 03596d65287ca72e2e09ee04d180cb6e 273 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 11-11-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS01705 03596d65287ca72e2e09ee04d180cb6e 273 Gene3D G3DSA:1.10.286.20 195 236 5.9E-12 T 11-11-2016 TW_RS01705 03596d65287ca72e2e09ee04d180cb6e 273 Gene3D G3DSA:1.10.8.10 3 55 6.1E-18 T 11-11-2016 TW_RS01705 03596d65287ca72e2e09ee04d180cb6e 273 Pfam PF00889 Elongation factor TS 71 272 2.4E-50 T 11-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS01705 03596d65287ca72e2e09ee04d180cb6e 273 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 3 272 2.2E-61 T 11-11-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS01705 03596d65287ca72e2e09ee04d180cb6e 273 SUPERFAMILY SSF46934 3 55 1.79E-12 T 11-11-2016 IPR009060 UBA-like GO:0005515 TW_RS01705 03596d65287ca72e2e09ee04d180cb6e 273 SUPERFAMILY SSF54713 176 272 2.45E-37 T 11-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS01705 03596d65287ca72e2e09ee04d180cb6e 273 SUPERFAMILY SSF54713 58 92 2.45E-37 T 11-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS01705 03596d65287ca72e2e09ee04d180cb6e 273 Gene3D G3DSA:3.30.479.20 58 93 1.2E-20 T 11-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS01705 03596d65287ca72e2e09ee04d180cb6e 273 Gene3D G3DSA:3.30.479.20 177 192 1.2E-20 T 11-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS01705 03596d65287ca72e2e09ee04d180cb6e 273 Gene3D G3DSA:3.30.479.20 238 272 1.2E-20 T 11-11-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS01705 03596d65287ca72e2e09ee04d180cb6e 273 Hamap MF_00050 Elongation factor Ts [tsf]. 1 273 51.286 T 11-11-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS00290 b9903e3dfe5d5105d42e9941b301cee9 239 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 19 234 1.9E-65 T 11-11-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TW_RS00290 b9903e3dfe5d5105d42e9941b301cee9 239 SUPERFAMILY SSF53335 15 232 3.8E-47 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS00290 b9903e3dfe5d5105d42e9941b301cee9 239 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 30 45 - T 11-11-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TW_RS00290 b9903e3dfe5d5105d42e9941b301cee9 239 Gene3D G3DSA:3.40.50.150 19 233 7.6E-50 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS00290 b9903e3dfe5d5105d42e9941b301cee9 239 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 145 159 - T 11-11-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TW_RS00290 b9903e3dfe5d5105d42e9941b301cee9 239 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 10 236 32.046 T 11-11-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TW_RS00290 b9903e3dfe5d5105d42e9941b301cee9 239 Pfam PF01209 ubiE/COQ5 methyltransferase family 17 235 7.5E-52 T 11-11-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TW_RS00945 09889d0d218f6129a056182b0c03aa5d 398 Gene3D G3DSA:1.10.510.10 100 188 9.9E-9 T 11-11-2016 TW_RS00945 09889d0d218f6129a056182b0c03aa5d 398 Gene3D G3DSA:3.30.200.20 21 99 2.5E-5 T 11-11-2016 TW_RS00945 09889d0d218f6129a056182b0c03aa5d 398 SUPERFAMILY SSF56112 25 194 6.56E-20 T 11-11-2016 IPR011009 Protein kinase-like domain TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 Gene3D G3DSA:1.10.287.80 248 281 1.3E-20 T 11-11-2016 TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 Gene3D G3DSA:1.10.287.80 20 61 1.3E-20 T 11-11-2016 TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 Pfam PF00231 ATP synthase 5 333 3.8E-71 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 PRINTS PR00126 ATP synthase gamma subunit signature 280 299 5.6E-20 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 5.6E-20 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 PRINTS PR00126 ATP synthase gamma subunit signature 311 332 5.6E-20 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 SUPERFAMILY SSF52943 200 333 6.28E-67 T 11-11-2016 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 SUPERFAMILY SSF52943 3 162 6.28E-67 T 11-11-2016 IPR023633 ATPase, F1 complex, gamma subunit domain Reactome: R-HSA-163210 TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 Gene3D G3DSA:1.10.287.80 282 328 1.7E-20 T 11-11-2016 TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 333 2.7E-74 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 333 29.015 T 11-11-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 Gene3D G3DSA:3.40.1380.10 64 164 2.7E-37 T 11-11-2016 TW_RS01825 d06aaf9a3f035f4861369b391a75ad7a 336 Gene3D G3DSA:3.40.1380.10 201 229 2.7E-37 T 11-11-2016 TW_RS00950 503325127b5741ba573e97f21f74f294 616 Pfam PF00009 Elongation factor Tu GTP binding domain 6 210 2.1E-49 T 11-11-2016 TW_RS00950 503325127b5741ba573e97f21f74f294 616 Pfam PF03144 Elongation factor Tu domain 2 234 305 2.1E-10 T 11-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TW_RS00950 503325127b5741ba573e97f21f74f294 616 SUPERFAMILY SSF50447 162 314 4.42E-29 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain TW_RS00950 503325127b5741ba573e97f21f74f294 616 Gene3D G3DSA:3.30.70.870 320 416 2.3E-29 T 11-11-2016 TW_RS00950 503325127b5741ba573e97f21f74f294 616 Gene3D G3DSA:2.40.30.10 221 319 4.0E-26 T 11-11-2016 TW_RS00950 503325127b5741ba573e97f21f74f294 616 Pfam PF00679 Elongation factor G C-terminus 413 497 2.2E-17 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain TW_RS00950 503325127b5741ba573e97f21f74f294 616 SUPERFAMILY SSF54980 415 527 6.23E-21 T 11-11-2016 IPR009022 Elongation factor G, III-V domain TW_RS00950 503325127b5741ba573e97f21f74f294 616 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 613 1.5E-236 T 11-11-2016 IPR006298 GTP-binding protein TypA GO:0005525 TW_RS00950 503325127b5741ba573e97f21f74f294 616 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 11-11-2016 IPR031157 Tr-type G domain, conserved site TW_RS00950 503325127b5741ba573e97f21f74f294 616 Gene3D G3DSA:3.30.70.240 417 497 4.2E-24 T 11-11-2016 IPR000640 Translation elongation factor EFG, V domain TW_RS00950 503325127b5741ba573e97f21f74f294 616 SUPERFAMILY SSF54980 319 403 6.71E-10 T 11-11-2016 IPR009022 Elongation factor G, III-V domain TW_RS00950 503325127b5741ba573e97f21f74f294 616 Gene3D G3DSA:2.40.50.250 498 592 3.6E-31 T 11-11-2016 TW_RS00950 503325127b5741ba573e97f21f74f294 616 SUPERFAMILY SSF52540 4 220 7.59E-50 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00950 503325127b5741ba573e97f21f74f294 616 Gene3D G3DSA:3.40.50.300 5 220 1.4E-55 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00950 503325127b5741ba573e97f21f74f294 616 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 145 1.8E-22 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TW_RS00950 503325127b5741ba573e97f21f74f294 616 PRINTS PR00315 GTP-binding elongation factor signature 75 85 1.1E-15 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS00950 503325127b5741ba573e97f21f74f294 616 PRINTS PR00315 GTP-binding elongation factor signature 127 136 1.1E-15 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS00950 503325127b5741ba573e97f21f74f294 616 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.1E-15 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS00950 503325127b5741ba573e97f21f74f294 616 PRINTS PR00315 GTP-binding elongation factor signature 91 102 1.1E-15 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS00950 503325127b5741ba573e97f21f74f294 616 PRINTS PR00315 GTP-binding elongation factor signature 51 59 1.1E-15 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 SUPERFAMILY SSF52313 6 230 2.09E-80 T 11-11-2016 IPR023591 Ribosomal protein S2, flavodoxin-like domain TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 Pfam PF00318 Ribosomal protein S2 9 222 8.6E-83 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 222 2.1E-91 T 11-11-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 PRINTS PR00395 Ribosomal protein S2 signature 173 184 7.4E-34 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 PRINTS PR00395 Ribosomal protein S2 signature 87 104 7.4E-34 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 PRINTS PR00395 Ribosomal protein S2 signature 37 46 7.4E-34 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 PRINTS PR00395 Ribosomal protein S2 signature 194 208 7.4E-34 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 PRINTS PR00395 Ribosomal protein S2 signature 6 24 7.4E-34 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 PRINTS PR00395 Ribosomal protein S2 signature 156 173 7.4E-34 T 11-11-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 Gene3D G3DSA:3.40.50.10490 156 243 3.4E-57 T 11-11-2016 TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 Gene3D G3DSA:3.40.50.10490 23 99 3.4E-57 T 11-11-2016 TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 Gene3D G3DSA:1.10.287.610 100 150 4.6E-17 T 11-11-2016 TW_RS01700 318a642d3b6f2fa08fdb3b972376ce6f 281 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 223 38.639 T 11-11-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 TW_RS02665 29b0cb4be5d84db68deea143e8ddc122 345 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 345 141.364 T 11-11-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TW_RS02665 29b0cb4be5d84db68deea143e8ddc122 345 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 30 333 5.1E-126 T 11-11-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TW_RS02665 29b0cb4be5d84db68deea143e8ddc122 345 SUPERFAMILY SSF46785 263 335 5.44E-22 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS02665 29b0cb4be5d84db68deea143e8ddc122 345 Gene3D G3DSA:1.10.8.60 189 262 2.0E-23 T 11-11-2016 TW_RS02665 29b0cb4be5d84db68deea143e8ddc122 345 Gene3D G3DSA:3.40.50.300 26 179 1.0E-28 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02665 29b0cb4be5d84db68deea143e8ddc122 345 SUPERFAMILY SSF52540 26 255 7.78E-48 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02665 29b0cb4be5d84db68deea143e8ddc122 345 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 16 240 4.6E-100 T 11-11-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 TW_RS02665 29b0cb4be5d84db68deea143e8ddc122 345 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 259 333 1.0E-36 T 11-11-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TW_RS02665 29b0cb4be5d84db68deea143e8ddc122 345 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 260 333 1.5E-28 T 11-11-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TW_RS02665 29b0cb4be5d84db68deea143e8ddc122 345 SMART SM00382 57 190 3.7E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS02665 29b0cb4be5d84db68deea143e8ddc122 345 Gene3D G3DSA:1.10.10.10 264 334 5.9E-29 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS03960 14d7827f511500d008ab86fbb7688a13 80 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 22 73 1.8E-12 T 11-11-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TW_RS03960 14d7827f511500d008ab86fbb7688a13 80 Gene3D G3DSA:1.20.5.1030 18 73 3.2E-14 T 11-11-2016 TW_RS03960 14d7827f511500d008ab86fbb7688a13 80 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 21 76 1.1E-10 T 11-11-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 TW_RS03960 14d7827f511500d008ab86fbb7688a13 80 Hamap MF_00422 Protein translocase subunit SecE [secE]. 19 74 11.04 T 11-11-2016 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TW_RS02810 19722df8b715539f046e5c17d2bf00d7 446 Pfam PF01546 Peptidase family M20/M25/M40 81 440 2.1E-29 T 11-11-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 TW_RS02810 19722df8b715539f046e5c17d2bf00d7 446 Pfam PF07687 Peptidase dimerisation domain 191 341 2.8E-12 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain TW_RS02810 19722df8b715539f046e5c17d2bf00d7 446 Gene3D G3DSA:3.40.630.10 381 444 4.2E-49 T 11-11-2016 TW_RS02810 19722df8b715539f046e5c17d2bf00d7 446 Gene3D G3DSA:3.40.630.10 11 203 4.2E-49 T 11-11-2016 TW_RS02810 19722df8b715539f046e5c17d2bf00d7 446 SUPERFAMILY SSF53187 357 443 1.31E-45 T 11-11-2016 TW_RS02810 19722df8b715539f046e5c17d2bf00d7 446 SUPERFAMILY SSF53187 6 193 1.31E-45 T 11-11-2016 TW_RS02810 19722df8b715539f046e5c17d2bf00d7 446 Gene3D G3DSA:3.30.70.360 204 349 3.0E-29 T 11-11-2016 IPR011650 Peptidase M20, dimerisation domain TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 Gene3D G3DSA:2.40.50.140 2 123 1.5E-62 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 Pfam PF00164 Ribosomal protein S12/S23 3 122 2.9E-42 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 PIRSF PIRSF002133 1 124 4.2E-53 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 6.3E-55 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 6.3E-55 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 6.3E-55 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 6.3E-55 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 6.3E-55 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 6.3E-55 T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 SUPERFAMILY SSF50249 2 123 1.11E-51 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 1.1E-64 T 11-11-2016 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.783 T 11-11-2016 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03765 d3bc3dd6d5e35ea748aba66f13b50723 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 11-11-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02610 3b3b2b939f38280d543f6c005b96193a 107 Pfam PF11969 Scavenger mRNA decapping enzyme C-term binding 4 101 2.9E-17 T 11-11-2016 TW_RS02610 3b3b2b939f38280d543f6c005b96193a 107 PRINTS PR00332 Histidine triad family signature 4 20 2.6E-14 T 11-11-2016 IPR001310 Histidine triad (HIT) protein TW_RS02610 3b3b2b939f38280d543f6c005b96193a 107 PRINTS PR00332 Histidine triad family signature 90 100 2.6E-14 T 11-11-2016 IPR001310 Histidine triad (HIT) protein TW_RS02610 3b3b2b939f38280d543f6c005b96193a 107 PRINTS PR00332 Histidine triad family signature 25 43 2.6E-14 T 11-11-2016 IPR001310 Histidine triad (HIT) protein TW_RS02610 3b3b2b939f38280d543f6c005b96193a 107 Gene3D G3DSA:3.30.428.10 3 103 3.9E-23 T 11-11-2016 IPR011146 HIT-like domain GO:0003824 TW_RS02610 3b3b2b939f38280d543f6c005b96193a 107 SUPERFAMILY SSF54197 2 102 3.56E-23 T 11-11-2016 IPR011146 HIT-like domain GO:0003824 TW_RS03005 47f0436b25ce44c5d0e09b33da937779 581 Gene3D G3DSA:3.40.50.1220 201 351 9.4E-57 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain TW_RS03005 47f0436b25ce44c5d0e09b33da937779 581 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 5 566 2.6E-207 T 11-11-2016 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TW_RS03005 47f0436b25ce44c5d0e09b33da937779 581 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 546 1.3E-47 T 11-11-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TW_RS03005 47f0436b25ce44c5d0e09b33da937779 581 SUPERFAMILY SSF52518 3 176 6.93E-56 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS03005 47f0436b25ce44c5d0e09b33da937779 581 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 170 1.9E-50 T 11-11-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TW_RS03005 47f0436b25ce44c5d0e09b33da937779 581 SUPERFAMILY SSF52518 370 571 2.14E-65 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS03005 47f0436b25ce44c5d0e09b33da937779 581 Gene3D G3DSA:3.40.50.970 3 175 8.8E-66 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS03005 47f0436b25ce44c5d0e09b33da937779 581 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 430 449 - T 11-11-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 TW_RS03005 47f0436b25ce44c5d0e09b33da937779 581 Gene3D G3DSA:3.40.50.970 352 560 8.4E-70 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS03005 47f0436b25ce44c5d0e09b33da937779 581 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 329 4.5E-43 T 11-11-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TW_RS03005 47f0436b25ce44c5d0e09b33da937779 581 SUPERFAMILY SSF52467 198 359 2.46E-54 T 11-11-2016 IPR029035 DHS-like NAD/FAD-binding domain TW_RS02255 3b21c803354ea9409af47569f139794f 466 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 20 314 1.4E-103 T 11-11-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TW_RS02255 3b21c803354ea9409af47569f139794f 466 SUPERFAMILY SSF52374 19 315 1.66E-76 T 11-11-2016 TW_RS02255 3b21c803354ea9409af47569f139794f 466 Gene3D G3DSA:1.20.120.640 308 400 3.2E-13 T 11-11-2016 TW_RS02255 3b21c803354ea9409af47569f139794f 466 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 457 2.1E-125 T 11-11-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TW_RS02255 3b21c803354ea9409af47569f139794f 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 60 69 3.7E-25 T 11-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TW_RS02255 3b21c803354ea9409af47569f139794f 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 24 35 3.7E-25 T 11-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TW_RS02255 3b21c803354ea9409af47569f139794f 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 3.7E-25 T 11-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TW_RS02255 3b21c803354ea9409af47569f139794f 466 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 3.7E-25 T 11-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TW_RS02255 3b21c803354ea9409af47569f139794f 466 Pfam PF09190 DALR domain 349 400 1.6E-5 T 11-11-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TW_RS02255 3b21c803354ea9409af47569f139794f 466 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 466 32.833 T 11-11-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TW_RS02255 3b21c803354ea9409af47569f139794f 466 SUPERFAMILY SSF47323 335 457 1.44E-18 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS02255 3b21c803354ea9409af47569f139794f 466 Gene3D G3DSA:3.40.50.620 20 306 9.7E-83 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS03575 1a23f256d9ed251ee0f2876d0546cd5a 187 Pfam PF03602 Conserved hypothetical protein 95 1 183 2.2E-41 T 11-11-2016 TW_RS03575 1a23f256d9ed251ee0f2876d0546cd5a 187 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 180 3.6E-35 T 11-11-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TW_RS03575 1a23f256d9ed251ee0f2876d0546cd5a 187 Gene3D G3DSA:3.40.50.150 1 184 9.6E-47 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS03575 1a23f256d9ed251ee0f2876d0546cd5a 187 PIRSF PIRSF004553 1 186 3.1E-44 T 11-11-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 TW_RS03575 1a23f256d9ed251ee0f2876d0546cd5a 187 SUPERFAMILY SSF53335 1 183 3.29E-37 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS03760 93643bf1cee3e132f33e761cb94dd088 156 SUPERFAMILY SSF47973 7 149 2.09E-54 T 11-11-2016 IPR023798 Ribosomal protein S7 domain TW_RS03760 93643bf1cee3e132f33e761cb94dd088 156 Gene3D G3DSA:1.10.455.10 9 156 1.2E-59 T 11-11-2016 IPR023798 Ribosomal protein S7 domain TW_RS03760 93643bf1cee3e132f33e761cb94dd088 156 PIRSF PIRSF002122 6 156 1.3E-54 T 11-11-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 TW_RS03760 93643bf1cee3e132f33e761cb94dd088 156 Pfam PF00177 Ribosomal protein S7p/S5e 2 149 1.2E-57 T 11-11-2016 IPR023798 Ribosomal protein S7 domain TW_RS03760 93643bf1cee3e132f33e761cb94dd088 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 33.645 T 11-11-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TW_RS03760 93643bf1cee3e132f33e761cb94dd088 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.7E-62 T 11-11-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TW_RS03760 93643bf1cee3e132f33e761cb94dd088 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 11-11-2016 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS03990 e6e09c2b0686cdc89f86fddebad42e35 486 Gene3D G3DSA:3.40.50.2020 275 446 2.7E-40 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like TW_RS03990 e6e09c2b0686cdc89f86fddebad42e35 486 Gene3D G3DSA:3.60.20.10 2 261 2.0E-57 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TW_RS03990 e6e09c2b0686cdc89f86fddebad42e35 486 SUPERFAMILY SSF53271 254 484 1.84E-64 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like TW_RS03990 e6e09c2b0686cdc89f86fddebad42e35 486 Pfam PF13522 Glutamine amidotransferase domain 65 201 5.9E-18 T 11-11-2016 TW_RS03990 e6e09c2b0686cdc89f86fddebad42e35 486 SUPERFAMILY SSF56235 2 261 4.12E-65 T 11-11-2016 IPR029055 Nucleophile aminohydrolases, N-terminal TW_RS03990 e6e09c2b0686cdc89f86fddebad42e35 486 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 469 43.34 T 11-11-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TW_RS03990 e6e09c2b0686cdc89f86fddebad42e35 486 PIRSF PIRSF000485 1 484 5.4E-154 T 11-11-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TW_RS03990 e6e09c2b0686cdc89f86fddebad42e35 486 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 467 4.7E-142 T 11-11-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TW_RS03990 e6e09c2b0686cdc89f86fddebad42e35 486 Pfam PF00156 Phosphoribosyl transferase domain 296 393 1.5E-7 T 11-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 TW_RS03605 0bd2e9401f0b9f536ede304fda47311e 322 Pfam PF02401 LytB protein 14 291 3.6E-84 T 11-11-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 TW_RS03605 0bd2e9401f0b9f536ede304fda47311e 322 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 12 295 35.437 T 11-11-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 TW_RS03605 0bd2e9401f0b9f536ede304fda47311e 322 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 14 291 9.0E-92 T 11-11-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 TW_RS02620 87133a0940917f4549519188a387e785 348 SMART SM00271 2 57 2.2E-24 T 11-11-2016 IPR001623 DnaJ domain TW_RS02620 87133a0940917f4549519188a387e785 348 Gene3D G3DSA:1.10.287.110 2 85 9.9E-27 T 11-11-2016 IPR001623 DnaJ domain TW_RS02620 87133a0940917f4549519188a387e785 348 Pfam PF00226 DnaJ domain 3 62 2.3E-22 T 11-11-2016 IPR001623 DnaJ domain TW_RS02620 87133a0940917f4549519188a387e785 348 ProSitePatterns PS00636 Nt-dnaJ domain signature. 42 61 - T 11-11-2016 IPR018253 DnaJ domain, conserved site TW_RS02620 87133a0940917f4549519188a387e785 348 Pfam PF00684 DnaJ central domain 122 186 1.7E-11 T 11-11-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 TW_RS02620 87133a0940917f4549519188a387e785 348 Pfam PF01556 DnaJ C terminal domain 189 306 2.4E-29 T 11-11-2016 IPR002939 Chaperone DnaJ, C-terminal TW_RS02620 87133a0940917f4549519188a387e785 348 SUPERFAMILY SSF46565 2 83 3.66E-27 T 11-11-2016 IPR001623 DnaJ domain TW_RS02620 87133a0940917f4549519188a387e785 348 Gene3D G3DSA:2.60.260.20 91 113 2.0E-13 T 11-11-2016 TW_RS02620 87133a0940917f4549519188a387e785 348 Gene3D G3DSA:2.60.260.20 192 233 2.0E-13 T 11-11-2016 TW_RS02620 87133a0940917f4549519188a387e785 348 Gene3D G3DSA:2.10.230.10 114 187 1.9E-14 T 11-11-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 TW_RS02620 87133a0940917f4549519188a387e785 348 Gene3D G3DSA:2.60.260.20 234 306 4.5E-17 T 11-11-2016 TW_RS02620 87133a0940917f4549519188a387e785 348 PRINTS PR00625 DnaJ domain signature 23 38 6.9E-11 T 11-11-2016 IPR001623 DnaJ domain TW_RS02620 87133a0940917f4549519188a387e785 348 PRINTS PR00625 DnaJ domain signature 5 23 6.9E-11 T 11-11-2016 IPR001623 DnaJ domain TW_RS02620 87133a0940917f4549519188a387e785 348 PRINTS PR00625 DnaJ domain signature 57 76 6.9E-11 T 11-11-2016 IPR001623 DnaJ domain TW_RS02620 87133a0940917f4549519188a387e785 348 SUPERFAMILY SSF49493 236 320 1.03E-16 T 11-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TW_RS02620 87133a0940917f4549519188a387e785 348 SUPERFAMILY SSF57938 111 187 6.28E-15 T 11-11-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 TW_RS02620 87133a0940917f4549519188a387e785 348 SUPERFAMILY SSF49493 90 127 7.19E-16 T 11-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TW_RS02620 87133a0940917f4549519188a387e785 348 SUPERFAMILY SSF49493 192 244 7.19E-16 T 11-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TW_RS02620 87133a0940917f4549519188a387e785 348 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 346 32.347 T 11-11-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 TW_RS01160 e9ac93bc6260a2cfe400647e879d5f28 93 SUPERFAMILY SSF54570 3 84 3.4E-34 T 11-11-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01160 e9ac93bc6260a2cfe400647e879d5f28 93 Pfam PF00203 Ribosomal protein S19 3 83 3.8E-36 T 11-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01160 e9ac93bc6260a2cfe400647e879d5f28 93 PIRSF PIRSF002144 1 93 1.7E-29 T 11-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01160 e9ac93bc6260a2cfe400647e879d5f28 93 Gene3D G3DSA:3.30.860.10 2 92 4.3E-40 T 11-11-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01160 e9ac93bc6260a2cfe400647e879d5f28 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 11-11-2016 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01160 e9ac93bc6260a2cfe400647e879d5f28 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 6.2E-24 T 11-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01160 e9ac93bc6260a2cfe400647e879d5f28 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 6.2E-24 T 11-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01160 e9ac93bc6260a2cfe400647e879d5f28 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 6.2E-24 T 11-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01160 e9ac93bc6260a2cfe400647e879d5f28 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 2 92 6.2E-46 T 11-11-2016 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 TW_RS01160 e9ac93bc6260a2cfe400647e879d5f28 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.133 T 11-11-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 413 419 - T 11-11-2016 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 SUPERFAMILY SSF55008 5 70 5.89E-12 T 11-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 Gene3D G3DSA:3.40.1110.10 427 503 7.3E-13 T 11-11-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 Gene3D G3DSA:3.40.50.1000 525 673 7.0E-44 T 11-11-2016 IPR023214 HAD-like domain TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 Gene3D G3DSA:3.40.50.1000 387 426 7.0E-44 T 11-11-2016 IPR023214 HAD-like domain TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 562 5.7E-20 T 11-11-2016 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 605 624 5.7E-20 T 11-11-2016 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 265 279 5.7E-20 T 11-11-2016 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 411 425 5.7E-20 T 11-11-2016 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 628 640 5.7E-20 T 11-11-2016 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 148 706 9.6E-151 T 11-11-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 190 692 4.8E-70 T 11-11-2016 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 Gene3D G3DSA:3.30.70.100 7 70 3.5E-14 T 11-11-2016 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 SUPERFAMILY SSF81665 188 221 1.83E-9 T 11-11-2016 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 SUPERFAMILY SSF81665 314 405 1.83E-9 T 11-11-2016 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 Pfam PF00122 E1-E2 ATPase 189 404 5.7E-58 T 11-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 Pfam PF00403 Heavy-metal-associated domain 9 65 5.4E-7 T 11-11-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 ProSitePatterns PS01229 Hypothetical cof family signature 2. 605 627 - T 11-11-2016 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 SUPERFAMILY SSF81653 226 315 1.26E-19 T 11-11-2016 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 130 708 1.5E-137 T 11-11-2016 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 Pfam PF00702 haloacid dehalogenase-like hydrolase 409 619 5.0E-37 T 11-11-2016 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 Gene3D G3DSA:2.70.150.10 156 316 3.5E-22 T 11-11-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 Reactome: R-HSA-936837 TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 SUPERFAMILY SSF56784 468 705 5.67E-51 T 11-11-2016 IPR023214 HAD-like domain TW_RS04410 2fa5dacb525ccdeb6d83c1fac6fff4d0 716 SUPERFAMILY SSF56784 409 429 5.67E-51 T 11-11-2016 IPR023214 HAD-like domain TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 Gene3D G3DSA:3.30.360.10 195 485 4.8E-110 T 11-11-2016 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 19 195 6.6E-49 T 11-11-2016 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 198 485 2.6E-103 T 11-11-2016 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 14 486 72.727 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 SUPERFAMILY SSF55347 185 485 8.83E-105 T 11-11-2016 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 151 164 3.0E-44 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 175 203 3.0E-44 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 227 244 3.0E-44 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 245 261 3.0E-44 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 335 361 3.0E-44 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 PIRSF PIRSF000110 4 487 1.1E-156 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 185 191 - T 11-11-2016 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 16 486 6.5E-167 T 11-11-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 Gene3D G3DSA:3.40.50.720 17 194 1.6E-55 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS02285 69ac1d00898cdfccc4c16081e15e8702 487 SUPERFAMILY SSF51735 13 198 3.74E-51 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS03555 82e5fba93a135db0e3fcb18b4f9789b3 504 Pfam PF07568 Histidine kinase 294 366 2.3E-19 T 11-11-2016 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain TW_RS03555 82e5fba93a135db0e3fcb18b4f9789b3 504 SUPERFAMILY SSF55874 374 496 1.13E-15 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS03555 82e5fba93a135db0e3fcb18b4f9789b3 504 Pfam PF12282 Signal transduction histidine kinase 5 113 7.0E-14 T 11-11-2016 IPR022066 Signal transduction histidine kinase TW_RS03555 82e5fba93a135db0e3fcb18b4f9789b3 504 Gene3D G3DSA:3.30.565.10 359 496 1.3E-12 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS03555 82e5fba93a135db0e3fcb18b4f9789b3 504 SMART SM00387 389 498 6.4E-5 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS03555 82e5fba93a135db0e3fcb18b4f9789b3 504 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 393 496 1.3E-6 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS03555 82e5fba93a135db0e3fcb18b4f9789b3 504 Gene3D G3DSA:3.30.450.20 177 276 1.3E-4 T 11-11-2016 TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 Gene3D G3DSA:2.40.30.10 303 396 1.4E-42 T 11-11-2016 TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 SUPERFAMILY SSF50447 208 304 1.98E-30 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 3.3E-56 T 11-11-2016 TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 SUPERFAMILY SSF50465 301 396 1.47E-32 T 11-11-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 Gene3D G3DSA:3.40.50.300 4 212 2.1E-69 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 397 7.1E-212 T 11-11-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 SUPERFAMILY SSF52540 9 229 7.36E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 57.553 T 11-11-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 54 69 - T 11-11-2016 IPR031157 Tr-type G domain, conserved site TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 148 4.2E-12 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 2.3E-29 T 11-11-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 Pfam PF03144 Elongation factor Tu domain 2 228 296 1.8E-17 T 11-11-2016 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 PRINTS PR00315 GTP-binding elongation factor signature 97 108 5.3E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 PRINTS PR00315 GTP-binding elongation factor signature 134 143 5.3E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 PRINTS PR00315 GTP-binding elongation factor signature 61 69 5.3E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 5.3E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 PRINTS PR00315 GTP-binding elongation factor signature 81 91 5.3E-24 T 11-11-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TW_RS00685 9a5ffc9a7594e1bd8ead7b73be2c577b 397 Gene3D G3DSA:2.40.30.10 213 301 8.1E-36 T 11-11-2016 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 Gene3D G3DSA:2.40.50.140 200 275 3.9E-30 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 SUPERFAMILY SSF50249 268 356 5.97E-24 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 SUPERFAMILY SSF50249 198 280 1.79E-26 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 Gene3D G3DSA:2.40.50.140 104 179 5.0E-15 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 Gene3D G3DSA:2.40.50.140 18 97 1.3E-16 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 Pfam PF00575 S1 RNA binding domain 26 96 1.5E-11 T 11-11-2016 IPR003029 S1 domain GO:0003676 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 Pfam PF00575 S1 RNA binding domain 116 179 1.6E-12 T 11-11-2016 IPR003029 S1 domain GO:0003676 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 Pfam PF00575 S1 RNA binding domain 198 268 2.9E-25 T 11-11-2016 IPR003029 S1 domain GO:0003676 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 Pfam PF00575 S1 RNA binding domain 282 354 1.4E-16 T 11-11-2016 IPR003029 S1 domain GO:0003676 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 SUPERFAMILY SSF50249 7 121 6.71E-22 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 SMART SM00316 198 268 2.2E-27 T 11-11-2016 IPR022967 RNA-binding domain, S1 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 SMART SM00316 112 179 6.3E-10 T 11-11-2016 IPR022967 RNA-binding domain, S1 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 SMART SM00316 283 354 5.5E-23 T 11-11-2016 IPR022967 RNA-binding domain, S1 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 SMART SM00316 25 96 8.4E-13 T 11-11-2016 IPR022967 RNA-binding domain, S1 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 SUPERFAMILY SSF50249 99 183 2.31E-14 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 PRINTS PR00681 Ribosomal protein S1 signature 117 133 1.9E-76 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 PRINTS PR00681 Ribosomal protein S1 signature 163 183 1.9E-76 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 PRINTS PR00681 Ribosomal protein S1 signature 27 45 1.9E-76 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 PRINTS PR00681 Ribosomal protein S1 signature 337 355 1.9E-76 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 PRINTS PR00681 Ribosomal protein S1 signature 220 241 1.9E-76 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 PRINTS PR00681 Ribosomal protein S1 signature 93 112 1.9E-76 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 PRINTS PR00681 Ribosomal protein S1 signature 45 59 1.9E-76 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 PRINTS PR00681 Ribosomal protein S1 signature 298 317 1.9E-76 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 PRINTS PR00681 Ribosomal protein S1 signature 134 151 1.9E-76 T 11-11-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 TW_RS02540 99765b965d66081ffabd8de04efe5e00 471 Gene3D G3DSA:2.40.50.140 276 356 3.1E-25 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01940 4604e2345999d5850d5e1cd19d2dbec1 287 SUPERFAMILY SSF52402 22 286 3.35E-71 T 11-11-2016 TW_RS01940 4604e2345999d5850d5e1cd19d2dbec1 287 Pfam PF02540 NAD synthase 37 277 8.9E-61 T 11-11-2016 IPR022310 NAD/GMP synthase TW_RS01940 4604e2345999d5850d5e1cd19d2dbec1 287 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 31 280 29.939 T 11-11-2016 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 TW_RS01940 4604e2345999d5850d5e1cd19d2dbec1 287 TIGRFAM TIGR00552 nadE: NAD+ synthetase 31 286 4.5E-66 T 11-11-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 TW_RS01940 4604e2345999d5850d5e1cd19d2dbec1 287 Gene3D G3DSA:3.40.50.620 23 281 8.2E-65 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS01295 59f4281a309b1f7d49cda053ad3719fa 452 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 361 373 - T 11-11-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TW_RS01295 59f4281a309b1f7d49cda053ad3719fa 452 SUPERFAMILY SSF53092 39 188 4.87E-21 T 11-11-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal TW_RS01295 59f4281a309b1f7d49cda053ad3719fa 452 Pfam PF05195 Aminopeptidase P, N-terminal domain 42 154 7.9E-16 T 11-11-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 TW_RS01295 59f4281a309b1f7d49cda053ad3719fa 452 SUPERFAMILY SSF55920 190 448 8.51E-64 T 11-11-2016 IPR000994 Peptidase M24, structural domain TW_RS01295 59f4281a309b1f7d49cda053ad3719fa 452 Pfam PF00557 Metallopeptidase family M24 196 425 2.3E-51 T 11-11-2016 IPR000994 Peptidase M24, structural domain TW_RS01295 59f4281a309b1f7d49cda053ad3719fa 452 SMART SM01011 35 172 1.8E-25 T 11-11-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 TW_RS01295 59f4281a309b1f7d49cda053ad3719fa 452 Gene3D G3DSA:3.90.230.10 193 447 4.1E-64 T 11-11-2016 IPR000994 Peptidase M24, structural domain TW_RS01295 59f4281a309b1f7d49cda053ad3719fa 452 Gene3D G3DSA:3.40.350.10 39 192 3.2E-22 T 11-11-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TW_RS02130 4334a735eb83b6b55560dbc2e352515a 166 Pfam PF01202 Shikimate kinase 10 157 2.2E-27 T 11-11-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TW_RS02130 4334a735eb83b6b55560dbc2e352515a 166 Gene3D G3DSA:3.40.50.300 1 159 3.5E-27 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02130 4334a735eb83b6b55560dbc2e352515a 166 SUPERFAMILY SSF52540 1 156 8.02E-17 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02130 4334a735eb83b6b55560dbc2e352515a 166 PRINTS PR01100 Shikimate kinase family signature 70 79 3.8E-9 T 11-11-2016 TW_RS02130 4334a735eb83b6b55560dbc2e352515a 166 PRINTS PR01100 Shikimate kinase family signature 3 18 3.8E-9 T 11-11-2016 TW_RS02130 4334a735eb83b6b55560dbc2e352515a 166 PRINTS PR01100 Shikimate kinase family signature 90 107 3.8E-9 T 11-11-2016 TW_RS02130 4334a735eb83b6b55560dbc2e352515a 166 PRINTS PR01100 Shikimate kinase family signature 27 40 3.8E-9 T 11-11-2016 TW_RS01565 e560711b262d5130ad18021af068e738 549 Pfam PF10150 Ribonuclease E/G family 178 443 2.6E-93 T 11-11-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 TW_RS01565 e560711b262d5130ad18021af068e738 549 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 78 465 4.6E-126 T 11-11-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 TW_RS01565 e560711b262d5130ad18021af068e738 549 Gene3D G3DSA:2.40.50.140 98 182 4.1E-25 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01565 e560711b262d5130ad18021af068e738 549 SUPERFAMILY SSF50249 103 182 5.94E-14 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 448 1.3E-130 T 11-11-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 Gene3D G3DSA:3.50.50.60 1 132 8.3E-35 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 310 1.3E-63 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 SUPERFAMILY SSF55424 329 448 1.29E-29 T 11-11-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.1E-40 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 1.1E-40 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-40 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 1.1E-40 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 1.1E-40 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 SUPERFAMILY SSF51905 1 354 1.77E-52 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 Gene3D G3DSA:3.50.50.60 133 319 3.1E-48 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 Gene3D G3DSA:3.30.390.30 329 448 3.0E-31 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 11-11-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PIRSF PIRSF000350 1 444 6.7E-71 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 330 438 2.8E-25 T 11-11-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 1.4E-67 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 433 1.4E-67 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 391 406 1.4E-67 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 191 1.4E-67 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.4E-67 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 290 297 1.4E-67 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 326 347 1.4E-67 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 1.4E-67 T 11-11-2016 TW_RS01405 f7b4a82dae73386779ae8042f0281b10 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 250 264 1.4E-67 T 11-11-2016 TW_RS02470 2f74b0949eaecac9d69d2dee533b24cb 291 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 52 270 4.8E-59 T 11-11-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 TW_RS02470 2f74b0949eaecac9d69d2dee533b24cb 291 Gene3D G3DSA:3.40.50.1360 46 282 6.7E-59 T 11-11-2016 TW_RS02470 2f74b0949eaecac9d69d2dee533b24cb 291 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 50 280 1.5E-52 T 11-11-2016 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 TW_RS02470 2f74b0949eaecac9d69d2dee533b24cb 291 SUPERFAMILY SSF100950 46 283 5.94E-56 T 11-11-2016 TW_RS02705 e337da62a5507f26f7f3370a0971d3c9 474 SUPERFAMILY SSF55931 104 473 6.96E-131 T 11-11-2016 TW_RS02705 e337da62a5507f26f7f3370a0971d3c9 474 SUPERFAMILY SSF54368 5 103 7.59E-29 T 11-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TW_RS02705 e337da62a5507f26f7f3370a0971d3c9 474 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 472 7.6E-184 T 11-11-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TW_RS02705 e337da62a5507f26f7f3370a0971d3c9 474 Gene3D G3DSA:3.30.590.10 107 453 3.4E-128 T 11-11-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TW_RS02705 e337da62a5507f26f7f3370a0971d3c9 474 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 97 5.2E-24 T 11-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TW_RS02705 e337da62a5507f26f7f3370a0971d3c9 474 SMART SM01230 104 383 2.7E-144 T 11-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TW_RS02705 e337da62a5507f26f7f3370a0971d3c9 474 Gene3D G3DSA:3.10.20.70 5 106 1.5E-30 T 11-11-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TW_RS02705 e337da62a5507f26f7f3370a0971d3c9 474 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 11-11-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TW_RS02705 e337da62a5507f26f7f3370a0971d3c9 474 Pfam PF00120 Glutamine synthetase, catalytic domain 105 471 1.4E-125 T 11-11-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TW_RS01225 8ec258792640fcdd7d780a2cdab68590 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 7.6E-16 T 11-11-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 TW_RS01225 8ec258792640fcdd7d780a2cdab68590 60 SUPERFAMILY SSF55129 3 59 9.42E-17 T 11-11-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TW_RS01225 8ec258792640fcdd7d780a2cdab68590 60 Gene3D G3DSA:3.30.1390.20 3 59 2.1E-19 T 11-11-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TW_RS01225 8ec258792640fcdd7d780a2cdab68590 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 1.2E-10 T 11-11-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TW_RS01225 8ec258792640fcdd7d780a2cdab68590 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 17.031 T 11-11-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 TW_RS01225 8ec258792640fcdd7d780a2cdab68590 60 PIRSF PIRSF002211 1 60 5.4E-24 T 11-11-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 TW_RS02980 f2fb476ebbf5ca32a995e30d9cc71855 373 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 339 4.6E-12 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS02980 f2fb476ebbf5ca32a995e30d9cc71855 373 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 1.3E-11 T 11-11-2016 TW_RS02980 f2fb476ebbf5ca32a995e30d9cc71855 373 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.3E-11 T 11-11-2016 TW_RS02980 f2fb476ebbf5ca32a995e30d9cc71855 373 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 327 1.3E-11 T 11-11-2016 TW_RS02980 f2fb476ebbf5ca32a995e30d9cc71855 373 Gene3D G3DSA:3.50.50.60 154 175 1.4E-24 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS02980 f2fb476ebbf5ca32a995e30d9cc71855 373 Gene3D G3DSA:3.50.50.60 7 95 1.4E-24 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS02980 f2fb476ebbf5ca32a995e30d9cc71855 373 Gene3D G3DSA:3.50.50.60 288 350 1.4E-24 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS02980 f2fb476ebbf5ca32a995e30d9cc71855 373 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 1.0E-11 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TW_RS02980 f2fb476ebbf5ca32a995e30d9cc71855 373 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 331 350 1.0E-11 T 11-11-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TW_RS02980 f2fb476ebbf5ca32a995e30d9cc71855 373 SUPERFAMILY SSF51905 7 82 1.65E-26 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS02980 f2fb476ebbf5ca32a995e30d9cc71855 373 SUPERFAMILY SSF51905 146 349 1.65E-26 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS02980 f2fb476ebbf5ca32a995e30d9cc71855 373 Gene3D G3DSA:3.50.50.60 176 270 3.0E-10 T 11-11-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TW_RS00270 2fc9b8824ba5eb41caa76c7c44e67f78 260 Pfam PF13614 AAA domain 7 179 4.3E-58 T 11-11-2016 IPR025669 AAA domain TW_RS00270 2fc9b8824ba5eb41caa76c7c44e67f78 260 Gene3D G3DSA:3.40.50.300 3 252 2.8E-64 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00270 2fc9b8824ba5eb41caa76c7c44e67f78 260 SUPERFAMILY SSF52540 6 253 1.31E-62 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03980 74bab24b4d0693b506d5ccd17d96c385 147 PRINTS PR01483 Fatty acid synthase signature 22 44 1.4E-6 T 11-11-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 TW_RS03980 74bab24b4d0693b506d5ccd17d96c385 147 PRINTS PR01483 Fatty acid synthase signature 44 65 1.4E-6 T 11-11-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 TW_RS03980 74bab24b4d0693b506d5ccd17d96c385 147 Gene3D G3DSA:3.10.129.10 9 138 9.3E-30 T 11-11-2016 IPR029069 HotDog domain TW_RS03980 74bab24b4d0693b506d5ccd17d96c385 147 Pfam PF01575 MaoC like domain 15 92 4.8E-21 T 11-11-2016 IPR002539 MaoC-like domain TW_RS03980 74bab24b4d0693b506d5ccd17d96c385 147 SUPERFAMILY SSF54637 9 92 2.34E-24 T 11-11-2016 IPR029069 HotDog domain TW_RS01440 771e1f2227cf6e293bcd3f93e8d50d45 220 Gene3D G3DSA:2.40.37.10 93 216 1.0E-28 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TW_RS01440 771e1f2227cf6e293bcd3f93e8d50d45 220 Pfam PF00842 Alanine racemase, C-terminal domain 100 216 3.2E-26 T 11-11-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TW_RS01440 771e1f2227cf6e293bcd3f93e8d50d45 220 SMART SM01005 99 219 7.2E-36 T 11-11-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TW_RS01440 771e1f2227cf6e293bcd3f93e8d50d45 220 SUPERFAMILY SSF50621 93 218 1.57E-27 T 11-11-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TW_RS01440 771e1f2227cf6e293bcd3f93e8d50d45 220 Gene3D G3DSA:3.20.20.10 31 74 3.9E-6 T 11-11-2016 IPR029066 PLP-binding barrel TW_RS02915 f3a064f9b38d66bceb075c8f69304a38 317 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 301 4.4E-89 T 11-11-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TW_RS02915 f3a064f9b38d66bceb075c8f69304a38 317 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 302 35.326 T 11-11-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TW_RS02915 f3a064f9b38d66bceb075c8f69304a38 317 SUPERFAMILY SSF81799 111 210 9.16E-33 T 11-11-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TW_RS02915 f3a064f9b38d66bceb075c8f69304a38 317 Gene3D G3DSA:3.40.50.150 213 303 2.3E-39 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS02915 f3a064f9b38d66bceb075c8f69304a38 317 Gene3D G3DSA:3.40.50.150 4 107 2.3E-39 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS02915 f3a064f9b38d66bceb075c8f69304a38 317 SUPERFAMILY SSF53335 210 302 2.65E-34 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS02915 f3a064f9b38d66bceb075c8f69304a38 317 SUPERFAMILY SSF53335 4 110 2.65E-34 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS02915 f3a064f9b38d66bceb075c8f69304a38 317 Gene3D G3DSA:1.10.150.170 110 212 3.0E-35 T 11-11-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TW_RS02915 f3a064f9b38d66bceb075c8f69304a38 317 Pfam PF01795 MraW methylase family 3 301 7.0E-101 T 11-11-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TW_RS02915 f3a064f9b38d66bceb075c8f69304a38 317 PIRSF PIRSF004486 1 303 1.7E-111 T 11-11-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TW_RS04040 25454c9f04e1c163f0722f3fab953d8a 323 SUPERFAMILY SSF51569 2 321 4.54E-110 T 11-11-2016 TW_RS04040 25454c9f04e1c163f0722f3fab953d8a 323 Gene3D G3DSA:3.20.20.70 2 321 2.3E-117 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS04040 25454c9f04e1c163f0722f3fab953d8a 323 PIRSF PIRSF001415 1 322 1.7E-117 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04040 25454c9f04e1c163f0722f3fab953d8a 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 293 312 2.2E-48 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04040 25454c9f04e1c163f0722f3fab953d8a 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 2.2E-48 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04040 25454c9f04e1c163f0722f3fab953d8a 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 2.2E-48 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04040 25454c9f04e1c163f0722f3fab953d8a 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 240 256 2.2E-48 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04040 25454c9f04e1c163f0722f3fab953d8a 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 265 280 2.2E-48 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04040 25454c9f04e1c163f0722f3fab953d8a 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 120 134 2.2E-48 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04040 25454c9f04e1c163f0722f3fab953d8a 323 SMART SM01004 2 319 4.8E-169 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04040 25454c9f04e1c163f0722f3fab953d8a 323 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 240 252 - T 11-11-2016 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04040 25454c9f04e1c163f0722f3fab953d8a 323 Pfam PF00490 Delta-aminolevulinic acid dehydratase 5 318 1.3E-114 T 11-11-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 2 475 73.136 T 11-11-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 1 443 2.2E-164 T 11-11-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 Gene3D G3DSA:3.20.20.70 2 474 8.3E-176 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 285 297 - T 11-11-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 SUPERFAMILY SSF51412 128 473 1.96E-107 T 11-11-2016 TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 SMART SM01240 1 462 1.1E-262 T 11-11-2016 TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 SMART SM00116 82 130 4.0E-8 T 11-11-2016 IPR000644 CBS domain TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 SMART SM00116 146 194 6.0E-7 T 11-11-2016 IPR000644 CBS domain TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 PIRSF PIRSF000130 1 475 4.2E-193 T 11-11-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 SUPERFAMILY SSF51412 1 133 3.66E-23 T 11-11-2016 TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 1 462 9.5E-141 T 11-11-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 Pfam PF00571 CBS domain 138 191 3.6E-8 T 11-11-2016 IPR000644 CBS domain TW_RS00425 de60d72a4ce3204200a5ef910f0c8c92 475 Pfam PF00571 CBS domain 79 124 3.5E-10 T 11-11-2016 IPR000644 CBS domain TW_RS04390 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 Pfam PF03023 MviN-like protein 39 471 8.5E-70 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TW_RS04390 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 34 53 9.4E-23 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TW_RS04390 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 269 295 9.4E-23 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TW_RS04390 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 129 153 9.4E-23 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TW_RS04390 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 363 382 9.4E-23 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TW_RS04390 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 53 69 9.4E-23 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TW_RS04390 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 418 435 9.4E-23 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TW_RS04390 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 PRINTS PR01806 Virulence factor MviN signature 153 174 9.4E-23 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TW_RS04390 0f3fa204a1b9ea5ac424ff355b8fd0c4 518 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 6 515 1.5E-70 T 11-11-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ TW_RS02475 76fdd88b2cdb630d0837ac22be0de01e 159 SUPERFAMILY SSF50324 3 158 5.49E-62 T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 TW_RS02475 76fdd88b2cdb630d0837ac22be0de01e 159 Gene3D G3DSA:3.90.80.10 2 158 1.8E-57 T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 TW_RS02475 76fdd88b2cdb630d0837ac22be0de01e 159 Pfam PF00719 Inorganic pyrophosphatase 6 157 2.3E-56 T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 TW_RS02475 76fdd88b2cdb630d0837ac22be0de01e 159 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 53 59 - T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 TW_RS02475 76fdd88b2cdb630d0837ac22be0de01e 159 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 2 159 34.586 T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 TW_RS03360 76fdd88b2cdb630d0837ac22be0de01e 159 SUPERFAMILY SSF50324 3 158 5.49E-62 T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 TW_RS03360 76fdd88b2cdb630d0837ac22be0de01e 159 Gene3D G3DSA:3.90.80.10 2 158 1.8E-57 T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 TW_RS03360 76fdd88b2cdb630d0837ac22be0de01e 159 Pfam PF00719 Inorganic pyrophosphatase 6 157 2.3E-56 T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 TW_RS03360 76fdd88b2cdb630d0837ac22be0de01e 159 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 53 59 - T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 TW_RS03360 76fdd88b2cdb630d0837ac22be0de01e 159 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 2 159 34.586 T 11-11-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1 TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 8 582 1.7E-140 T 11-11-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 385 535 2.3E-45 T 11-11-2016 IPR001162 UvrC family homology region TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 SMART SM00465 12 93 1.1E-17 T 11-11-2016 IPR000305 GIY-YIG nuclease superfamily TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 SUPERFAMILY SSF46600 188 237 3.01E-11 T 11-11-2016 IPR001943 UVR domain GO:0005515 TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 SUPERFAMILY SSF82771 12 95 3.27E-19 T 11-11-2016 IPR000305 GIY-YIG nuclease superfamily TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 Gene3D G3DSA:4.10.860.10 184 237 4.3E-13 T 11-11-2016 IPR001943 UVR domain GO:0005515 TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 Pfam PF02151 UvrB/uvrC motif 202 234 9.0E-8 T 11-11-2016 IPR001943 UVR domain GO:0005515 TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 Gene3D G3DSA:1.10.150.20 549 599 1.0E-13 T 11-11-2016 TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 SUPERFAMILY SSF47781 495 600 2.41E-16 T 11-11-2016 IPR010994 RuvA domain 2-like TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 Pfam PF14520 Helix-hairpin-helix domain 550 601 9.5E-11 T 11-11-2016 TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 Gene3D G3DSA:3.40.1440.10 12 85 2.6E-6 T 11-11-2016 IPR027299 GIY-YIG domain TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 600 24.573 T 11-11-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 TW_RS02520 fbea8810b7c2b53e707291b5a5572e7e 607 Pfam PF01541 GIY-YIG catalytic domain 13 85 1.9E-10 T 11-11-2016 IPR000305 GIY-YIG nuclease superfamily TW_RS02725 8c3e2e5fc4d0395dcdc5bd2f406a0a35 279 SUPERFAMILY SSF102705 8 277 4.97E-71 T 11-11-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TW_RS02725 8c3e2e5fc4d0395dcdc5bd2f406a0a35 279 Gene3D G3DSA:3.40.1390.30 6 114 8.4E-37 T 11-11-2016 TW_RS02725 8c3e2e5fc4d0395dcdc5bd2f406a0a35 279 Gene3D G3DSA:3.40.1390.30 115 230 9.1E-26 T 11-11-2016 TW_RS02725 8c3e2e5fc4d0395dcdc5bd2f406a0a35 279 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 8 262 3.6E-71 T 11-11-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TW_RS02725 8c3e2e5fc4d0395dcdc5bd2f406a0a35 279 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 8 271 5.5E-41 T 11-11-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TW_RS03675 0e2f9f14ab994d1bb84791ff2a262515 344 SUPERFAMILY SSF103025 29 251 8.63E-36 T 11-11-2016 TW_RS03675 0e2f9f14ab994d1bb84791ff2a262515 344 SUPERFAMILY SSF101790 255 328 1.64E-6 T 11-11-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain TW_RS03675 0e2f9f14ab994d1bb84791ff2a262515 344 Gene3D G3DSA:2.40.30.110 253 323 3.7E-6 T 11-11-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TW_RS03675 0e2f9f14ab994d1bb84791ff2a262515 344 Gene3D G3DSA:3.30.70.1400 54 129 5.4E-5 T 11-11-2016 TW_RS03675 0e2f9f14ab994d1bb84791ff2a262515 344 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 204 261 2.3E-16 T 11-11-2016 IPR017703 YgfZ/GcvT conserved site TW_RS03675 0e2f9f14ab994d1bb84791ff2a262515 344 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 236 323 3.0E-9 T 11-11-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TW_RS02605 87a5857a4df3df2edb22106adcf913ce 171 Pfam PF02130 Uncharacterized protein family UPF0054 35 144 2.9E-28 T 11-11-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TW_RS02605 87a5857a4df3df2edb22106adcf913ce 171 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 115 125 - T 11-11-2016 IPR020549 Endoribonuclease YbeY, conserved site TW_RS02605 87a5857a4df3df2edb22106adcf913ce 171 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 144 7.8E-26 T 11-11-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TW_RS02605 87a5857a4df3df2edb22106adcf913ce 171 Gene3D G3DSA:3.40.390.30 16 146 9.5E-32 T 11-11-2016 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 TW_RS02605 87a5857a4df3df2edb22106adcf913ce 171 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 4 155 19.514 T 11-11-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TW_RS02605 87a5857a4df3df2edb22106adcf913ce 171 SUPERFAMILY SSF55486 19 143 3.57E-30 T 11-11-2016 TW_RS01850 0e0ed1351bbeaec5b73184c01dc84230 312 SUPERFAMILY SSF161111 23 220 2.62E-41 T 11-11-2016 TW_RS01850 0e0ed1351bbeaec5b73184c01dc84230 312 Pfam PF01545 Cation efflux family 26 219 1.9E-36 T 11-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TW_RS01850 0e0ed1351bbeaec5b73184c01dc84230 312 Gene3D G3DSA:1.20.1510.10 24 219 5.6E-45 T 11-11-2016 IPR027469 Cation efflux protein transmembrane domain TW_RS01850 0e0ed1351bbeaec5b73184c01dc84230 312 SUPERFAMILY SSF160240 221 297 4.71E-8 T 11-11-2016 TW_RS01850 0e0ed1351bbeaec5b73184c01dc84230 312 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 24 296 2.6E-62 T 11-11-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TW_RS01260 90b249ac0c4d07fa44d858c30880307f 130 Pfam PF00411 Ribosomal protein S11 20 128 1.9E-46 T 11-11-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TW_RS01260 90b249ac0c4d07fa44d858c30880307f 130 ProSitePatterns PS00054 Ribosomal protein S11 signature. 98 120 - T 11-11-2016 IPR018102 Ribosomal S11, conserved site TW_RS01260 90b249ac0c4d07fa44d858c30880307f 130 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 11 127 8.1E-56 T 11-11-2016 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01260 90b249ac0c4d07fa44d858c30880307f 130 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 130 32.332 T 11-11-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TW_RS01260 90b249ac0c4d07fa44d858c30880307f 130 PIRSF PIRSF002131 1 130 1.8E-53 T 11-11-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TW_RS01260 90b249ac0c4d07fa44d858c30880307f 130 Gene3D G3DSA:3.30.420.80 7 128 4.5E-53 T 11-11-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TW_RS01260 90b249ac0c4d07fa44d858c30880307f 130 SUPERFAMILY SSF53137 15 128 1.31E-46 T 11-11-2016 TW_RS01215 570d75a16a9446bc1fc997994077a5de 119 SUPERFAMILY SSF53137 6 117 1.26E-45 T 11-11-2016 TW_RS01215 570d75a16a9446bc1fc997994077a5de 119 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 5 119 26.186 T 11-11-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01215 570d75a16a9446bc1fc997994077a5de 119 Gene3D G3DSA:3.30.420.100 24 118 2.1E-34 T 11-11-2016 TW_RS01215 570d75a16a9446bc1fc997994077a5de 119 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 118 2.9E-37 T 11-11-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01215 570d75a16a9446bc1fc997994077a5de 119 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 5 118 9.8E-45 T 11-11-2016 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03075 3278f4b175c2deca833086824bfecfe2 376 Gene3D G3DSA:1.20.58.410 3 110 1.9E-20 T 11-11-2016 TW_RS03075 3278f4b175c2deca833086824bfecfe2 376 Gene3D G3DSA:3.30.160.20 230 303 2.8E-33 T 11-11-2016 IPR014720 Double-stranded RNA-binding domain TW_RS03075 3278f4b175c2deca833086824bfecfe2 376 SMART SM00937 84 194 1.8E-35 T 11-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 TW_RS03075 3278f4b175c2deca833086824bfecfe2 376 SUPERFAMILY SSF75620 29 366 2.49E-110 T 11-11-2016 TW_RS03075 3278f4b175c2deca833086824bfecfe2 376 Pfam PF00472 RF-1 domain 230 336 1.8E-35 T 11-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TW_RS03075 3278f4b175c2deca833086824bfecfe2 376 Pfam PF03462 PCRF domain 30 219 2.4E-48 T 11-11-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 TW_RS03075 3278f4b175c2deca833086824bfecfe2 376 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 363 2.6E-129 T 11-11-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 TW_RS03075 3278f4b175c2deca833086824bfecfe2 376 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 244 260 - T 11-11-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TW_RS01805 7c61eff8a0496323861745573f7c31c0 75 ProSitePatterns PS00605 ATP synthase c subunit signature. 40 61 - T 11-11-2016 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210 TW_RS01805 7c61eff8a0496323861745573f7c31c0 75 PRINTS PR00124 ATP synthase C subunit signature 50 75 9.0E-14 T 11-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 TW_RS01805 7c61eff8a0496323861745573f7c31c0 75 PRINTS PR00124 ATP synthase C subunit signature 12 31 9.0E-14 T 11-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 TW_RS01805 7c61eff8a0496323861745573f7c31c0 75 PRINTS PR00124 ATP synthase C subunit signature 33 48 9.0E-14 T 11-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 TW_RS01805 7c61eff8a0496323861745573f7c31c0 75 Pfam PF00137 ATP synthase subunit C 13 72 1.4E-11 T 11-11-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TW_RS01805 7c61eff8a0496323861745573f7c31c0 75 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 20 72 1.1E-18 T 11-11-2016 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 TW_RS01805 7c61eff8a0496323861745573f7c31c0 75 Gene3D G3DSA:1.20.20.10 13 74 1.3E-22 T 11-11-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210 TW_RS01805 7c61eff8a0496323861745573f7c31c0 75 Hamap MF_01396 ATP synthase subunit c [atpH]. 9 75 12.76 T 11-11-2016 TW_RS01805 7c61eff8a0496323861745573f7c31c0 75 SUPERFAMILY SSF81333 13 74 5.89E-17 T 11-11-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TW_RS03350 306b6b8654a77a924299e9eb3bd41283 317 Gene3D G3DSA:3.30.300.20 252 314 4.0E-23 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta TW_RS03350 306b6b8654a77a924299e9eb3bd41283 317 Gene3D G3DSA:3.30.1480.10 1 92 2.8E-13 T 11-11-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 TW_RS03350 306b6b8654a77a924299e9eb3bd41283 317 SUPERFAMILY SSF69705 1 93 1.31E-15 T 11-11-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 TW_RS03350 306b6b8654a77a924299e9eb3bd41283 317 SUPERFAMILY SSF50249 105 173 5.0E-11 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS03350 306b6b8654a77a924299e9eb3bd41283 317 SUPERFAMILY SSF54814 174 252 2.75E-25 T 11-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 TW_RS03350 306b6b8654a77a924299e9eb3bd41283 317 Gene3D G3DSA:2.40.50.140 102 172 8.1E-18 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS03350 306b6b8654a77a924299e9eb3bd41283 317 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 70 314 2.3E-81 T 11-11-2016 IPR010213 Transcription termination factor NusA GO:0003723 TW_RS03350 306b6b8654a77a924299e9eb3bd41283 317 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 317 21.158 T 11-11-2016 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 TW_RS03350 306b6b8654a77a924299e9eb3bd41283 317 Gene3D G3DSA:3.30.300.20 173 251 7.3E-30 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta TW_RS03350 306b6b8654a77a924299e9eb3bd41283 317 Pfam PF13184 NusA-like KH domain 204 271 2.2E-21 T 11-11-2016 IPR025249 KH domain, NusA-like GO:0003723 TW_RS03350 306b6b8654a77a924299e9eb3bd41283 317 SUPERFAMILY SSF54814 254 313 5.1E-14 T 11-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 TW_RS04245 93b14951ed8448499ee6f707fb7ec3d7 293 Gene3D G3DSA:3.40.50.150 79 285 2.8E-82 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS04245 93b14951ed8448499ee6f707fb7ec3d7 293 Gene3D G3DSA:3.40.50.150 12 45 2.8E-82 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS04245 93b14951ed8448499ee6f707fb7ec3d7 293 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 95 114 2.1E-23 T 11-11-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TW_RS04245 93b14951ed8448499ee6f707fb7ec3d7 293 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 217 239 2.1E-23 T 11-11-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TW_RS04245 93b14951ed8448499ee6f707fb7ec3d7 293 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 240 254 2.1E-23 T 11-11-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TW_RS04245 93b14951ed8448499ee6f707fb7ec3d7 293 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 33 45 2.1E-23 T 11-11-2016 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 TW_RS04245 93b14951ed8448499ee6f707fb7ec3d7 293 SUPERFAMILY SSF53335 11 48 1.13E-68 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS04245 93b14951ed8448499ee6f707fb7ec3d7 293 SUPERFAMILY SSF53335 82 280 1.13E-68 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS04245 93b14951ed8448499ee6f707fb7ec3d7 293 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 36 42 - T 11-11-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TW_RS04245 93b14951ed8448499ee6f707fb7ec3d7 293 Pfam PF01555 DNA methylase 34 274 1.3E-46 T 11-11-2016 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 16 566 3.1E-225 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 Gene3D G3DSA:1.10.730.10 600 738 7.5E-25 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 Gene3D G3DSA:3.90.740.10 236 414 6.8E-41 T 11-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 Pfam PF08264 Anticodon-binding domain of tRNA 646 765 1.3E-12 T 11-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 SUPERFAMILY SSF47323 616 804 9.16E-20 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 Gene3D G3DSA:3.40.50.620 13 235 9.2E-141 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 Gene3D G3DSA:3.40.50.620 415 599 9.2E-141 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 235 373 1.6E-42 T 11-11-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 15 803 19.972 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 SUPERFAMILY SSF50677 237 412 1.88E-35 T 11-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 SUPERFAMILY SSF52374 14 240 5.16E-132 T 11-11-2016 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 SUPERFAMILY SSF52374 409 616 5.16E-132 T 11-11-2016 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 Pfam PF09334 tRNA synthetases class I (M) 53 183 3.2E-16 T 11-11-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 553 563 1.0E-52 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 139 156 1.0E-52 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 198 211 1.0E-52 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 481 499 1.0E-52 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 520 542 1.0E-52 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 165 181 1.0E-52 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 PRINTS PR00985 Leucyl-tRNA synthetase signature 229 248 1.0E-52 T 11-11-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 410 610 8.1E-22 T 11-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS02060 7cf6bab6c5a46d3ffbe0bc677e46b3ea 806 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 56 65 - T 11-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS02670 976e651e5bde91ca5268649bca79de11 174 Pfam PF01330 RuvA N terminal domain 2 39 5.5E-9 T 11-11-2016 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 TW_RS02670 976e651e5bde91ca5268649bca79de11 174 Gene3D G3DSA:1.10.150.20 45 119 2.2E-24 T 11-11-2016 TW_RS02670 976e651e5bde91ca5268649bca79de11 174 SMART SM00278 50 69 0.8 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TW_RS02670 976e651e5bde91ca5268649bca79de11 174 SMART SM00278 85 104 160.0 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TW_RS02670 976e651e5bde91ca5268649bca79de11 174 SUPERFAMILY SSF46929 126 172 1.03E-9 T 11-11-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 TW_RS02670 976e651e5bde91ca5268649bca79de11 174 SUPERFAMILY SSF47781 44 113 1.11E-17 T 11-11-2016 IPR010994 RuvA domain 2-like TW_RS02670 976e651e5bde91ca5268649bca79de11 174 Pfam PF07499 RuvA, C-terminal domain 125 170 4.7E-11 T 11-11-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 TW_RS02670 976e651e5bde91ca5268649bca79de11 174 Gene3D G3DSA:1.10.8.10 121 173 1.5E-13 T 11-11-2016 TW_RS02670 976e651e5bde91ca5268649bca79de11 174 SUPERFAMILY SSF50249 2 40 1.09E-5 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02670 976e651e5bde91ca5268649bca79de11 174 Pfam PF14520 Helix-hairpin-helix domain 49 105 1.4E-13 T 11-11-2016 TW_RS02670 976e651e5bde91ca5268649bca79de11 174 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 171 19.992 T 11-11-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TW_RS02670 976e651e5bde91ca5268649bca79de11 174 Gene3D G3DSA:2.40.50.140 2 42 2.6E-10 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS00650 0bd31cf66b5dfc41dd98557298075f26 217 Gene3D G3DSA:2.30.30.90 146 216 3.0E-9 T 11-11-2016 TW_RS00650 0bd31cf66b5dfc41dd98557298075f26 217 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 1 52 1.2E-8 T 11-11-2016 IPR022687 DTXR-type HTH domain GO:0003677 TW_RS00650 0bd31cf66b5dfc41dd98557298075f26 217 Gene3D G3DSA:1.10.10.10 1 64 2.4E-17 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS00650 0bd31cf66b5dfc41dd98557298075f26 217 SMART SM00529 18 117 4.0E-33 T 11-11-2016 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 TW_RS00650 0bd31cf66b5dfc41dd98557298075f26 217 SUPERFAMILY SSF50037 123 216 3.48E-16 T 11-11-2016 IPR008988 Transcriptional repressor, C-terminal TW_RS00650 0bd31cf66b5dfc41dd98557298075f26 217 SUPERFAMILY SSF47979 57 129 2.75E-23 T 11-11-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 TW_RS00650 0bd31cf66b5dfc41dd98557298075f26 217 Gene3D G3DSA:1.10.60.10 67 128 2.6E-24 T 11-11-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 TW_RS00650 0bd31cf66b5dfc41dd98557298075f26 217 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 57 125 5.2E-25 T 11-11-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 TW_RS00650 0bd31cf66b5dfc41dd98557298075f26 217 SUPERFAMILY SSF46785 1 54 3.08E-7 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS00840 19c7dd1555cc204ec3ca15bed969d776 251 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 36 173 1.5E-10 T 11-11-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 TW_RS00840 19c7dd1555cc204ec3ca15bed969d776 251 Gene3D G3DSA:3.40.50.300 9 238 3.8E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00840 19c7dd1555cc204ec3ca15bed969d776 251 SUPERFAMILY SSF52540 9 238 4.59E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01075 9c12e7c236e712031eb76fe41c6f77d4 443 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 13 443 26.667 T 11-11-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TW_RS01075 9c12e7c236e712031eb76fe41c6f77d4 443 Gene3D G3DSA:3.65.10.10 25 255 1.5E-56 T 11-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 TW_RS01075 9c12e7c236e712031eb76fe41c6f77d4 443 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 19 439 7.7E-105 T 11-11-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TW_RS01075 9c12e7c236e712031eb76fe41c6f77d4 443 Gene3D G3DSA:3.65.10.10 256 438 5.6E-49 T 11-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 TW_RS01075 9c12e7c236e712031eb76fe41c6f77d4 443 SUPERFAMILY SSF55205 20 439 5.05E-99 T 11-11-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TW_RS01075 9c12e7c236e712031eb76fe41c6f77d4 443 PIRSF PIRSF000505 5 443 2.0E-105 T 11-11-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TW_RS01075 9c12e7c236e712031eb76fe41c6f77d4 443 ProSitePatterns PS00885 EPSP synthase signature 2. 356 374 - T 11-11-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TW_RS01075 9c12e7c236e712031eb76fe41c6f77d4 443 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 19 435 4.9E-97 T 11-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 Hamap MF_00123 Arginine--tRNA ligase [argS]. 4 552 22.502 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 Gene3D G3DSA:1.10.730.10 433 552 2.7E-37 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 Gene3D G3DSA:3.30.1360.70 5 105 1.5E-16 T 11-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 SMART SM01016 4 87 3.8E-18 T 11-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 SUPERFAMILY SSF47323 422 552 1.05E-34 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 Gene3D G3DSA:3.40.50.620 111 432 1.3E-73 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 SUPERFAMILY SSF55190 5 107 2.22E-15 T 11-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 4 552 7.5E-103 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 5 87 1.7E-13 T 11-11-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 Pfam PF05746 DALR anticodon binding domain 428 552 6.5E-30 T 11-11-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 PRINTS PR01038 Arginyl-tRNA synthetase signature 116 131 1.3E-19 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 PRINTS PR01038 Arginyl-tRNA synthetase signature 297 318 1.3E-19 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 PRINTS PR01038 Arginyl-tRNA synthetase signature 155 168 1.3E-19 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 PRINTS PR01038 Arginyl-tRNA synthetase signature 131 147 1.3E-19 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 SMART SM00836 428 552 1.3E-43 T 11-11-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 SUPERFAMILY SSF52374 110 438 2.13E-71 T 11-11-2016 TW_RS02235 02cae9c5d72377c0a8dc222c22313775 552 Pfam PF00750 tRNA synthetases class I (R) 96 389 1.9E-15 T 11-11-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TW_RS02070 7ea550d81f0e3ecdd7ba5bee0c0d45fa 472 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 217 391 4.2E-15 T 11-11-2016 IPR004477 ComEC/Rec2-related protein TW_RS02070 7ea550d81f0e3ecdd7ba5bee0c0d45fa 472 Pfam PF03772 Competence protein 195 457 3.4E-34 T 11-11-2016 IPR004477 ComEC/Rec2-related protein TW_RS00925 4c1ccae57b2c17ffc9321c798741a6c3 572 Pfam PF00664 ABC transporter transmembrane region 21 274 2.5E-8 T 11-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TW_RS00925 4c1ccae57b2c17ffc9321c798741a6c3 572 Pfam PF00005 ABC transporter 352 499 9.5E-31 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS00925 4c1ccae57b2c17ffc9321c798741a6c3 572 SUPERFAMILY SSF90123 11 318 3.01E-34 T 11-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TW_RS00925 4c1ccae57b2c17ffc9321c798741a6c3 572 SMART SM00382 361 546 2.0E-15 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00925 4c1ccae57b2c17ffc9321c798741a6c3 572 SUPERFAMILY SSF52540 330 564 9.97E-73 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00925 4c1ccae57b2c17ffc9321c798741a6c3 572 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS00925 4c1ccae57b2c17ffc9321c798741a6c3 572 Gene3D G3DSA:1.20.1560.10 13 316 2.2E-25 T 11-11-2016 TW_RS00925 4c1ccae57b2c17ffc9321c798741a6c3 572 Gene3D G3DSA:3.40.50.300 336 560 1.5E-69 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02365 e67bcedb2366a460c264fbd94c42d840 356 Pfam PF13407 Periplasmic binding protein domain 51 320 2.0E-57 T 11-11-2016 IPR025997 Periplasmic binding protein TW_RS02365 e67bcedb2366a460c264fbd94c42d840 356 SUPERFAMILY SSF53822 48 355 3.44E-58 T 11-11-2016 IPR028082 Periplasmic binding protein-like I TW_RS02365 e67bcedb2366a460c264fbd94c42d840 356 Gene3D G3DSA:3.40.50.2300 162 353 8.4E-34 T 11-11-2016 TW_RS02365 e67bcedb2366a460c264fbd94c42d840 356 Gene3D G3DSA:3.40.50.2300 49 161 1.8E-19 T 11-11-2016 TW_RS02945 512f92479f241509a1913aadb471d7a1 455 SUPERFAMILY SSF51569 16 455 5.2E-185 T 11-11-2016 TW_RS02945 512f92479f241509a1913aadb471d7a1 455 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 21 454 2.2E-195 T 11-11-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TW_RS02945 512f92479f241509a1913aadb471d7a1 455 Pfam PF01474 Class-II DAHP synthetase family 22 451 1.7E-189 T 11-11-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TW_RS02350 e900df065574355f844d1267ef4cbd42 254 Gene3D G3DSA:3.40.1180.10 12 253 7.8E-73 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TW_RS02350 e900df065574355f844d1267ef4cbd42 254 Pfam PF01255 Putative undecaprenyl diphosphate synthase 33 253 3.2E-61 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TW_RS02350 e900df065574355f844d1267ef4cbd42 254 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 26 254 32.954 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TW_RS02350 e900df065574355f844d1267ef4cbd42 254 SUPERFAMILY SSF64005 21 248 6.8E-63 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TW_RS02350 e900df065574355f844d1267ef4cbd42 254 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 199 216 - T 11-11-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 TW_RS02350 e900df065574355f844d1267ef4cbd42 254 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 26 253 1.3E-53 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TW_RS02890 770cc72d1ddc22c0d8a3d83dc800be30 509 Pfam PF08245 Mur ligase middle domain 122 324 7.9E-41 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS02890 770cc72d1ddc22c0d8a3d83dc800be30 509 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 8 502 25.74 T 11-11-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 TW_RS02890 770cc72d1ddc22c0d8a3d83dc800be30 509 SUPERFAMILY SSF63418 26 112 4.45E-9 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TW_RS02890 770cc72d1ddc22c0d8a3d83dc800be30 509 Gene3D G3DSA:3.40.1390.10 28 112 1.2E-6 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TW_RS02890 770cc72d1ddc22c0d8a3d83dc800be30 509 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 33 500 2.0E-91 T 11-11-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 TW_RS02890 770cc72d1ddc22c0d8a3d83dc800be30 509 Gene3D G3DSA:3.90.190.20 355 493 2.4E-33 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02890 770cc72d1ddc22c0d8a3d83dc800be30 509 SUPERFAMILY SSF53244 349 503 1.27E-30 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02890 770cc72d1ddc22c0d8a3d83dc800be30 509 Gene3D G3DSA:3.40.1190.10 116 354 2.9E-49 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS02890 770cc72d1ddc22c0d8a3d83dc800be30 509 Pfam PF02875 Mur ligase family, glutamate ligase domain 350 433 2.3E-14 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02890 770cc72d1ddc22c0d8a3d83dc800be30 509 SUPERFAMILY SSF53623 113 342 9.55E-50 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS02870 cb5f25b68643270dc60f7a7394b26668 475 SUPERFAMILY SSF53623 103 322 9.55E-44 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS02870 cb5f25b68643270dc60f7a7394b26668 475 Pfam PF01225 Mur ligase family, catalytic domain 17 114 2.7E-18 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TW_RS02870 cb5f25b68643270dc60f7a7394b26668 475 SUPERFAMILY SSF51984 16 101 2.22E-21 T 11-11-2016 TW_RS02870 cb5f25b68643270dc60f7a7394b26668 475 SUPERFAMILY SSF53244 323 470 1.58E-35 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02870 cb5f25b68643270dc60f7a7394b26668 475 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 17 467 4.8E-107 T 11-11-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS02870 cb5f25b68643270dc60f7a7394b26668 475 Gene3D G3DSA:3.90.190.20 326 472 3.5E-42 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02870 cb5f25b68643270dc60f7a7394b26668 475 Gene3D G3DSA:3.40.1190.10 103 325 5.2E-51 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS02870 cb5f25b68643270dc60f7a7394b26668 475 Pfam PF08245 Mur ligase middle domain 119 303 1.1E-14 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS02870 cb5f25b68643270dc60f7a7394b26668 475 Pfam PF02875 Mur ligase family, glutamate ligase domain 326 412 2.5E-18 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02870 cb5f25b68643270dc60f7a7394b26668 475 Gene3D G3DSA:3.40.50.720 16 102 3.8E-25 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS04460 d797756b4ed9d0dde8be1c9c58ee7570 193 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 13 189 2.1E-64 T 11-11-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TW_RS04460 d797756b4ed9d0dde8be1c9c58ee7570 193 Gene3D G3DSA:3.30.63.10 41 94 1.1E-23 T 11-11-2016 TW_RS04460 d797756b4ed9d0dde8be1c9c58ee7570 193 Gene3D G3DSA:3.40.50.300 14 34 8.9E-31 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04460 d797756b4ed9d0dde8be1c9c58ee7570 193 Gene3D G3DSA:3.40.50.300 95 190 8.9E-31 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04460 d797756b4ed9d0dde8be1c9c58ee7570 193 Hamap MF_00328 Guanylate kinase [gmk]. 10 193 31.536 T 11-11-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TW_RS04460 d797756b4ed9d0dde8be1c9c58ee7570 193 SMART SM00072 12 187 3.1E-39 T 11-11-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TW_RS04460 d797756b4ed9d0dde8be1c9c58ee7570 193 ProSitePatterns PS00856 Guanylate kinase-like signature. 46 63 - T 11-11-2016 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 TW_RS04460 d797756b4ed9d0dde8be1c9c58ee7570 193 Pfam PF00625 Guanylate kinase 15 187 2.1E-37 T 11-11-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TW_RS04460 d797756b4ed9d0dde8be1c9c58ee7570 193 SUPERFAMILY SSF52540 13 190 3.98E-51 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01730 bb6100a6cac4ee3ba73b4f80cbf5ba5e 180 TIGRFAM TIGR03543 divI1A_rptt_fam: DivIVA domain repeat protein 6 178 2.4E-74 T 11-11-2016 IPR019932 Conserved hypothetical protein CHP03543 TW_RS01730 bb6100a6cac4ee3ba73b4f80cbf5ba5e 180 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 39 71 4.1E-11 T 11-11-2016 IPR019933 DivIVA domain TW_RS01730 bb6100a6cac4ee3ba73b4f80cbf5ba5e 180 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 141 170 7.3E-10 T 11-11-2016 IPR019933 DivIVA domain TW_RS01730 bb6100a6cac4ee3ba73b4f80cbf5ba5e 180 Gene3D G3DSA:1.10.10.10 50 70 4.9E-4 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS00985 8ee95f3272d883cc4f28dbd14e58ea06 181 Pfam PF01227 GTP cyclohydrolase I 13 153 3.1E-35 T 11-11-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|Reactome: R-HSA-1474151 TW_RS00985 8ee95f3272d883cc4f28dbd14e58ea06 181 Gene3D G3DSA:1.10.286.10 11 56 9.5E-4 T 11-11-2016 TW_RS00985 8ee95f3272d883cc4f28dbd14e58ea06 181 SUPERFAMILY SSF55620 9 172 1.78E-37 T 11-11-2016 TW_RS00985 8ee95f3272d883cc4f28dbd14e58ea06 181 Gene3D G3DSA:3.30.1130.10 64 168 1.7E-28 T 11-11-2016 TW_RS03000 3634e44a84c3bb2b38ad9bc888983ec0 114 Pfam PF01842 ACT domain 40 103 1.6E-13 T 11-11-2016 IPR002912 ACT domain GO:0008152|GO:0016597 TW_RS03000 3634e44a84c3bb2b38ad9bc888983ec0 114 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 40 106 1.0E-31 T 11-11-2016 TW_RS03000 3634e44a84c3bb2b38ad9bc888983ec0 114 Gene3D G3DSA:3.30.70.260 39 107 6.0E-19 T 11-11-2016 TW_RS03000 3634e44a84c3bb2b38ad9bc888983ec0 114 SUPERFAMILY SSF55021 39 109 9.92E-15 T 11-11-2016 TW_RS02460 df14830768373fd7d2401f58761f9a54 201 SUPERFAMILY SSF56420 9 187 7.46E-47 T 11-11-2016 IPR023635 Peptide deformylase TW_RS02460 df14830768373fd7d2401f58761f9a54 201 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 14 176 3.2E-34 T 11-11-2016 IPR023635 Peptide deformylase TW_RS02460 df14830768373fd7d2401f58761f9a54 201 PRINTS PR01576 Peptide deformylase signature 124 142 7.7E-32 T 11-11-2016 IPR023635 Peptide deformylase TW_RS02460 df14830768373fd7d2401f58761f9a54 201 PRINTS PR01576 Peptide deformylase signature 143 172 7.7E-32 T 11-11-2016 IPR023635 Peptide deformylase TW_RS02460 df14830768373fd7d2401f58761f9a54 201 PRINTS PR01576 Peptide deformylase signature 112 123 7.7E-32 T 11-11-2016 IPR023635 Peptide deformylase TW_RS02460 df14830768373fd7d2401f58761f9a54 201 PRINTS PR01576 Peptide deformylase signature 38 67 7.7E-32 T 11-11-2016 IPR023635 Peptide deformylase TW_RS02460 df14830768373fd7d2401f58761f9a54 201 Gene3D G3DSA:3.90.45.10 9 198 3.1E-53 T 11-11-2016 IPR023635 Peptide deformylase TW_RS02460 df14830768373fd7d2401f58761f9a54 201 PIRSF PIRSF004749 2 192 2.0E-40 T 11-11-2016 IPR023635 Peptide deformylase TW_RS02460 df14830768373fd7d2401f58761f9a54 201 Pfam PF01327 Polypeptide deformylase 11 173 5.0E-40 T 11-11-2016 IPR023635 Peptide deformylase TW_RS02460 df14830768373fd7d2401f58761f9a54 201 Hamap MF_00163 Peptide deformylase [def]. 8 185 25.233 T 11-11-2016 IPR023635 Peptide deformylase TW_RS00375 2c3ba5b1c19a0a048a30cdb743b56a32 74 Pfam PF13396 Phospholipase_D-nuclease N-terminal 14 58 1.3E-10 T 11-11-2016 IPR027379 Cardiolipin synthase N-terminal TW_RS02300 9608e4c5aa3a135d1f804598d73afa86 698 Gene3D G3DSA:3.40.50.970 369 558 6.3E-73 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS02300 9608e4c5aa3a135d1f804598d73afa86 698 SUPERFAMILY SSF52518 20 343 4.29E-94 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS02300 9608e4c5aa3a135d1f804598d73afa86 698 Pfam PF02779 Transketolase, pyrimidine binding domain 373 553 2.6E-45 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TW_RS02300 9608e4c5aa3a135d1f804598d73afa86 698 Pfam PF02780 Transketolase, C-terminal domain 580 685 8.9E-10 T 11-11-2016 IPR033248 Transketolase, C-terminal domain TW_RS02300 9608e4c5aa3a135d1f804598d73afa86 698 TIGRFAM TIGR00232 tktlase_bact: transketolase 26 693 2.9E-228 T 11-11-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 TW_RS02300 9608e4c5aa3a135d1f804598d73afa86 698 SMART SM00861 374 554 3.1E-65 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TW_RS02300 9608e4c5aa3a135d1f804598d73afa86 698 Gene3D G3DSA:3.40.50.920 568 693 2.9E-43 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TW_RS02300 9608e4c5aa3a135d1f804598d73afa86 698 SUPERFAMILY SSF52518 362 556 1.2E-67 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS02300 9608e4c5aa3a135d1f804598d73afa86 698 Gene3D G3DSA:3.40.50.970 22 344 2.7E-100 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS02300 9608e4c5aa3a135d1f804598d73afa86 698 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 24 359 8.0E-122 T 11-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TW_RS02300 9608e4c5aa3a135d1f804598d73afa86 698 SUPERFAMILY SSF52922 565 695 5.14E-38 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TW_RS02300 9608e4c5aa3a135d1f804598d73afa86 698 ProSitePatterns PS00801 Transketolase signature 1. 31 51 - T 11-11-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TW_RS00355 b3df8b56216ae9346e43136e868942d6 288 Hamap MF_00158 Pantothenate synthetase [panC]. 4 285 29.733 T 11-11-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TW_RS00355 b3df8b56216ae9346e43136e868942d6 288 SUPERFAMILY SSF52374 8 285 4.22E-69 T 11-11-2016 TW_RS00355 b3df8b56216ae9346e43136e868942d6 288 Gene3D G3DSA:3.30.1300.10 179 285 2.5E-8 T 11-11-2016 TW_RS00355 b3df8b56216ae9346e43136e868942d6 288 Pfam PF02569 Pantoate-beta-alanine ligase 17 283 9.6E-68 T 11-11-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TW_RS00355 b3df8b56216ae9346e43136e868942d6 288 Gene3D G3DSA:3.40.50.620 17 168 4.0E-58 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS02600 4664715fda4929881c8fee7ecee34449 301 Pfam PF07650 KH domain 213 289 2.1E-16 T 11-11-2016 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS02600 4664715fda4929881c8fee7ecee34449 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 14 283 2.9E-56 T 11-11-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 TW_RS02600 4664715fda4929881c8fee7ecee34449 301 SUPERFAMILY SSF54814 195 297 2.94E-31 T 11-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 TW_RS02600 4664715fda4929881c8fee7ecee34449 301 Pfam PF01926 50S ribosome-binding GTPase 15 100 4.9E-19 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS02600 4664715fda4929881c8fee7ecee34449 301 Hamap MF_00367 GTPase Era [era]. 10 300 29.208 T 11-11-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 TW_RS02600 4664715fda4929881c8fee7ecee34449 301 Gene3D G3DSA:3.30.300.20 197 295 7.2E-32 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta TW_RS02600 4664715fda4929881c8fee7ecee34449 301 SUPERFAMILY SSF52540 15 180 3.89E-32 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02600 4664715fda4929881c8fee7ecee34449 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 15 164 1.7E-17 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TW_RS02600 4664715fda4929881c8fee7ecee34449 301 Gene3D G3DSA:3.40.50.300 11 174 2.0E-32 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02825 e765e82d8f71ec9571d92f80be7924aa 335 Gene3D G3DSA:3.20.20.70 3 333 2.1E-105 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS02825 e765e82d8f71ec9571d92f80be7924aa 335 SUPERFAMILY SSF51395 3 332 1.31E-84 T 11-11-2016 TW_RS02825 e765e82d8f71ec9571d92f80be7924aa 335 Pfam PF01180 Dihydroorotate dehydrogenase 41 332 7.3E-81 T 11-11-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TW_RS02825 e765e82d8f71ec9571d92f80be7924aa 335 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 76 95 - T 11-11-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TW_RS02825 e765e82d8f71ec9571d92f80be7924aa 335 PIRSF PIRSF000164 11 335 3.2E-97 T 11-11-2016 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 TW_RS02825 e765e82d8f71ec9571d92f80be7924aa 335 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 4 333 7.4E-97 T 11-11-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS02825 e765e82d8f71ec9571d92f80be7924aa 335 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 286 306 - T 11-11-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TW_RS04340 bc8e203b06f2a1ca5714a11da33058d1 334 Gene3D G3DSA:3.40.50.920 209 329 2.6E-38 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TW_RS04340 bc8e203b06f2a1ca5714a11da33058d1 334 Pfam PF02779 Transketolase, pyrimidine binding domain 19 189 1.1E-40 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TW_RS04340 bc8e203b06f2a1ca5714a11da33058d1 334 SUPERFAMILY SSF52922 203 332 2.62E-34 T 11-11-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 TW_RS04340 bc8e203b06f2a1ca5714a11da33058d1 334 SUPERFAMILY SSF52518 18 215 5.54E-58 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS04340 bc8e203b06f2a1ca5714a11da33058d1 334 SMART SM00861 18 191 1.0E-57 T 11-11-2016 IPR005475 Transketolase-like, pyrimidine-binding domain TW_RS04340 bc8e203b06f2a1ca5714a11da33058d1 334 Gene3D G3DSA:3.40.50.970 17 194 1.4E-64 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS04340 bc8e203b06f2a1ca5714a11da33058d1 334 Pfam PF02780 Transketolase, C-terminal domain 207 324 2.4E-31 T 11-11-2016 IPR033248 Transketolase, C-terminal domain TW_RS00620 8d3f61d257d9e16ffd6d787ef1f6965b 186 SUPERFAMILY SSF50249 4 186 9.94E-39 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS00620 8d3f61d257d9e16ffd6d787ef1f6965b 186 Pfam PF00436 Single-strand binding protein family 4 104 2.9E-23 T 11-11-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 TW_RS00620 8d3f61d257d9e16ffd6d787ef1f6965b 186 Hamap MF_00984 Single-stranded DNA-binding protein. 2 111 28.783 T 11-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TW_RS00620 8d3f61d257d9e16ffd6d787ef1f6965b 186 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 4 186 1.7E-28 T 11-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TW_RS00620 8d3f61d257d9e16ffd6d787ef1f6965b 186 Gene3D G3DSA:2.40.50.140 4 114 1.2E-34 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01695 2ea96565a0bd18b3bb98545083f99e9c 231 SUPERFAMILY SSF51261 35 141 1.36E-15 T 11-11-2016 IPR011055 Duplicated hybrid motif TW_RS01695 2ea96565a0bd18b3bb98545083f99e9c 231 Pfam PF01551 Peptidase family M23 68 139 3.7E-14 T 11-11-2016 IPR016047 Peptidase M23 TW_RS01695 2ea96565a0bd18b3bb98545083f99e9c 231 Gene3D G3DSA:2.70.70.10 195 221 1.6E-38 T 11-11-2016 TW_RS01695 2ea96565a0bd18b3bb98545083f99e9c 231 Gene3D G3DSA:2.70.70.10 22 139 1.6E-38 T 11-11-2016 TW_RS01980 95ae15e2e0e90ac9c8e1f44daf92b809 155 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 5 152 1.9E-44 T 11-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TW_RS01980 95ae15e2e0e90ac9c8e1f44daf92b809 155 Gene3D G3DSA:3.40.1400.10 4 154 1.0E-46 T 11-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TW_RS01980 95ae15e2e0e90ac9c8e1f44daf92b809 155 PIRSF PIRSF005384 3 155 3.0E-42 T 11-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TW_RS01980 95ae15e2e0e90ac9c8e1f44daf92b809 155 Pfam PF02502 Ribose/Galactose Isomerase 5 148 6.2E-39 T 11-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TW_RS01980 95ae15e2e0e90ac9c8e1f44daf92b809 155 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 4 154 4.6E-71 T 11-11-2016 IPR011860 Ribose 5-phosphate isomerase GO:0004751 TW_RS01980 95ae15e2e0e90ac9c8e1f44daf92b809 155 SUPERFAMILY SSF89623 4 152 1.29E-45 T 11-11-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 Gene3D G3DSA:1.20.50.20 359 416 6.7E-4 T 11-11-2016 TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 PIRSF PIRSF002811 1 600 7.5E-145 T 11-11-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 TIGRFAM TIGR01391 dnaG: DNA primase 4 405 7.4E-116 T 11-11-2016 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 Pfam PF10410 DnaB-helicase binding domain of primase 361 415 1.1E-11 T 11-11-2016 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 SMART SM00493 250 324 2.2E-11 T 11-11-2016 IPR006171 Toprim domain TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 Pfam PF08275 DNA primase catalytic core, N-terminal domain 121 242 1.7E-34 T 11-11-2016 IPR013264 DNA primase, catalytic core, N-terminal TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 SUPERFAMILY SSF57783 1 96 7.82E-31 T 11-11-2016 TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 Gene3D G3DSA:3.40.1360.10 232 357 3.7E-36 T 11-11-2016 TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 SUPERFAMILY SSF56731 111 415 1.88E-87 T 11-11-2016 TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 Gene3D G3DSA:3.90.580.10 2 99 1.1E-34 T 11-11-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 Pfam PF13662 Toprim domain 251 317 1.7E-13 T 11-11-2016 IPR006171 Toprim domain TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 Hamap MF_00974 DNA primase [dnaG]. 3 591 24.837 T 11-11-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 Pfam PF01807 CHC2 zinc finger 5 98 7.4E-33 T 11-11-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 SMART SM00400 36 89 1.2E-29 T 11-11-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TW_RS02580 21812f3fdfe16ec61bcfee6c55052b2e 603 Gene3D G3DSA:3.90.980.10 111 231 1.4E-33 T 11-11-2016 IPR013264 DNA primase, catalytic core, N-terminal TW_RS01615 823bba19c8d7010bba290f2f4f6d1321 184 SUPERFAMILY SSF46767 103 181 5.76E-22 T 11-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TW_RS01615 823bba19c8d7010bba290f2f4f6d1321 184 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 104 180 3.7E-22 T 11-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TW_RS01615 823bba19c8d7010bba290f2f4f6d1321 184 Gene3D G3DSA:1.10.10.10 101 181 1.1E-25 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS01615 823bba19c8d7010bba290f2f4f6d1321 184 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 104 180 1.2E-22 T 11-11-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TW_RS01615 823bba19c8d7010bba290f2f4f6d1321 184 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 149 155 - T 11-11-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 325 3.0E-72 T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 11-11-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 SUPERFAMILY SSF51230 510 588 8.51E-21 T 11-11-2016 IPR011053 Single hybrid motif TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 6.2E-37 T 11-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 SUPERFAMILY SSF51246 332 448 1.88E-38 T 11-11-2016 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 Gene3D G3DSA:3.30.1490.20 132 204 1.8E-23 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 SUPERFAMILY SSF52440 2 115 1.65E-44 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 Pfam PF00364 Biotin-requiring enzyme 525 588 3.3E-16 T 11-11-2016 IPR000089 Biotin/lipoyl attachment TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 Gene3D G3DSA:3.40.50.20 4 131 1.6E-45 T 11-11-2016 IPR016185 Pre-ATP-grasp domain TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 112 1.5E-41 T 11-11-2016 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 Gene3D G3DSA:3.30.470.20 205 449 7.1E-87 T 11-11-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 SMART SM00878 337 443 5.1E-53 T 11-11-2016 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 Gene3D G3DSA:2.40.50.100 514 589 3.1E-24 T 11-11-2016 TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 SUPERFAMILY SSF56059 117 326 2.47E-56 T 11-11-2016 TW_RS00110 50dc3447a70822f521e5390d8dbb7771 591 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 545 562 - T 11-11-2016 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS02220 6de7bfb590c5eed387c524db1b71bb1e 297 SUPERFAMILY SSF161098 28 284 1.44E-37 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TW_RS02220 6de7bfb590c5eed387c524db1b71bb1e 297 Gene3D G3DSA:1.10.3720.10 17 290 4.7E-40 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TW_RS02220 6de7bfb590c5eed387c524db1b71bb1e 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 293 4.3E-22 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TW_RS02220 6de7bfb590c5eed387c524db1b71bb1e 297 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 18 289 1.2E-77 T 11-11-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 TW_RS02900 68c0af630229d4a361031553d077f61f 464 Pfam PF01225 Mur ligase family, catalytic domain 32 84 9.8E-8 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TW_RS02900 68c0af630229d4a361031553d077f61f 464 SUPERFAMILY SSF53244 316 453 1.52E-23 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02900 68c0af630229d4a361031553d077f61f 464 Gene3D G3DSA:3.40.1190.10 101 312 3.5E-53 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS02900 68c0af630229d4a361031553d077f61f 464 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 34 453 1.8E-94 T 11-11-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS02900 68c0af630229d4a361031553d077f61f 464 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 456 27.953 T 11-11-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS02900 68c0af630229d4a361031553d077f61f 464 Gene3D G3DSA:3.90.190.20 314 457 2.2E-24 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02900 68c0af630229d4a361031553d077f61f 464 SUPERFAMILY SSF63418 29 98 7.19E-18 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TW_RS02900 68c0af630229d4a361031553d077f61f 464 Pfam PF02875 Mur ligase family, glutamate ligase domain 316 393 2.1E-5 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02900 68c0af630229d4a361031553d077f61f 464 SUPERFAMILY SSF53623 107 313 2.09E-46 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS02900 68c0af630229d4a361031553d077f61f 464 Gene3D G3DSA:3.40.1390.10 8 85 2.0E-16 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TW_RS02900 68c0af630229d4a361031553d077f61f 464 Pfam PF08245 Mur ligase middle domain 112 293 3.0E-37 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS03320 03c641d0a4ca7678b312b50f392d1384 182 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 2 70 1.6E-27 T 11-11-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TW_RS03320 03c641d0a4ca7678b312b50f392d1384 182 ProSitePatterns PS00938 Initiation factor 3 signature. 52 65 - T 11-11-2016 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 TW_RS03320 03c641d0a4ca7678b312b50f392d1384 182 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 3 163 9.6E-53 T 11-11-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TW_RS03320 03c641d0a4ca7678b312b50f392d1384 182 Gene3D G3DSA:3.10.20.80 2 71 6.9E-29 T 11-11-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TW_RS03320 03c641d0a4ca7678b312b50f392d1384 182 SUPERFAMILY SSF54364 2 72 1.44E-24 T 11-11-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TW_RS03320 03c641d0a4ca7678b312b50f392d1384 182 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 77 161 1.5E-28 T 11-11-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 TW_RS03320 03c641d0a4ca7678b312b50f392d1384 182 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 164 24.494 T 11-11-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TW_RS03320 03c641d0a4ca7678b312b50f392d1384 182 Gene3D G3DSA:3.30.110.10 74 165 6.0E-30 T 11-11-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 TW_RS03320 03c641d0a4ca7678b312b50f392d1384 182 SUPERFAMILY SSF55200 78 162 4.19E-26 T 11-11-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 TW_RS03200 2bd541ce9db265914e97c0314f9114cc 318 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 5 310 3.7E-105 T 11-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TW_RS03200 2bd541ce9db265914e97c0314f9114cc 318 Pfam PF14572 Phosphoribosyl synthetase-associated domain 206 308 5.4E-19 T 11-11-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TW_RS03200 2bd541ce9db265914e97c0314f9114cc 318 SMART SM01400 4 120 1.6E-63 T 11-11-2016 TW_RS03200 2bd541ce9db265914e97c0314f9114cc 318 SUPERFAMILY SSF53271 2 157 2.13E-49 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like TW_RS03200 2bd541ce9db265914e97c0314f9114cc 318 Gene3D G3DSA:3.40.50.2020 1 159 2.2E-68 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like TW_RS03200 2bd541ce9db265914e97c0314f9114cc 318 Gene3D G3DSA:3.40.50.2020 160 278 1.1E-38 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like TW_RS03200 2bd541ce9db265914e97c0314f9114cc 318 SUPERFAMILY SSF53271 106 298 8.61E-40 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like TW_RS03200 2bd541ce9db265914e97c0314f9114cc 318 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 4 120 8.1E-40 T 11-11-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TW_RS03200 2bd541ce9db265914e97c0314f9114cc 318 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 128 143 - T 11-11-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 TW_RS00410 fb82f283e0528f0338946a1a164a8122 1275 Pfam PF04983 RNA polymerase Rpb1, domain 3 551 701 9.5E-22 T 11-11-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00410 fb82f283e0528f0338946a1a164a8122 1275 Pfam PF05000 RNA polymerase Rpb1, domain 4 739 793 8.7E-10 T 11-11-2016 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00410 fb82f283e0528f0338946a1a164a8122 1275 Pfam PF00623 RNA polymerase Rpb1, domain 2 406 547 7.8E-35 T 11-11-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00410 fb82f283e0528f0338946a1a164a8122 1275 Pfam PF04997 RNA polymerase Rpb1, domain 1 1 404 5.1E-75 T 11-11-2016 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00410 fb82f283e0528f0338946a1a164a8122 1275 SMART SM00663 297 576 6.6E-166 T 11-11-2016 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00410 fb82f283e0528f0338946a1a164a8122 1275 Gene3D G3DSA:2.40.50.100 1013 1065 6.0E-6 T 11-11-2016 TW_RS00410 fb82f283e0528f0338946a1a164a8122 1275 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 1 1231 9.788 T 11-11-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00410 fb82f283e0528f0338946a1a164a8122 1275 SUPERFAMILY SSF64484 1 1219 0.0 T 11-11-2016 TW_RS00410 fb82f283e0528f0338946a1a164a8122 1275 Pfam PF04998 RNA polymerase Rpb1, domain 5 808 1170 3.4E-64 T 11-11-2016 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS00410 fb82f283e0528f0338946a1a164a8122 1275 Gene3D G3DSA:2.40.40.20 411 438 5.9E-37 T 11-11-2016 TW_RS00410 fb82f283e0528f0338946a1a164a8122 1275 Gene3D G3DSA:2.40.40.20 479 551 5.9E-37 T 11-11-2016 TW_RS00410 fb82f283e0528f0338946a1a164a8122 1275 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 1 1222 0.0 T 11-11-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 Hamap MF_02005 Valine--tRNA ligase [valS]. 3 839 27.508 T 11-11-2016 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 SUPERFAMILY SSF47323 632 850 2.99E-37 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 16 616 4.2E-91 T 11-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 Gene3D G3DSA:1.10.730.10 603 771 1.6E-29 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 Gene3D G3DSA:3.40.50.620 3 210 9.6E-102 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 Gene3D G3DSA:3.40.50.620 377 602 9.6E-102 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 Gene3D G3DSA:3.90.740.10 219 361 2.8E-24 T 11-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 11-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 SUPERFAMILY SSF52374 2 214 9.25E-106 T 11-11-2016 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 SUPERFAMILY SSF52374 374 619 9.25E-106 T 11-11-2016 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 PRINTS PR00986 Valyl-tRNA synthetase signature 379 392 1.1E-16 T 11-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 PRINTS PR00986 Valyl-tRNA synthetase signature 250 267 1.1E-16 T 11-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 PRINTS PR00986 Valyl-tRNA synthetase signature 499 520 1.1E-16 T 11-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 PRINTS PR00986 Valyl-tRNA synthetase signature 40 51 1.1E-16 T 11-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 PRINTS PR00986 Valyl-tRNA synthetase signature 530 548 1.1E-16 T 11-11-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 Pfam PF08264 Anticodon-binding domain of tRNA 675 808 6.9E-26 T 11-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 TW_RS01540 2c12a24637f7c9c62255dc24d17c4a77 856 SUPERFAMILY SSF50677 218 357 7.59E-30 T 11-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TW_RS01870 63407df990f15baafd81e6ffe8f0da58 383 Pfam PF00266 Aminotransferase class-V 267 368 8.2E-10 T 11-11-2016 IPR000192 Aminotransferase class V domain TW_RS01870 63407df990f15baafd81e6ffe8f0da58 383 Pfam PF00266 Aminotransferase class-V 6 238 8.5E-25 T 11-11-2016 IPR000192 Aminotransferase class V domain TW_RS01870 63407df990f15baafd81e6ffe8f0da58 383 PIRSF PIRSF005572 4 381 4.4E-67 T 11-11-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 TW_RS01870 63407df990f15baafd81e6ffe8f0da58 383 Gene3D G3DSA:3.90.1150.10 260 372 4.8E-31 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TW_RS01870 63407df990f15baafd81e6ffe8f0da58 383 SUPERFAMILY SSF53383 5 378 4.76E-56 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase TW_RS01870 63407df990f15baafd81e6ffe8f0da58 383 Gene3D G3DSA:3.40.640.10 21 259 6.3E-37 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TW_RS03790 800ce661bda4d1b515d9f1d050c05355 327 PIRSF PIRSF000355 1 326 1.3E-107 T 11-11-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS03790 800ce661bda4d1b515d9f1d050c05355 327 Gene3D G3DSA:1.10.620.20 14 299 6.0E-87 T 11-11-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: R-HSA-499943 TW_RS03790 800ce661bda4d1b515d9f1d050c05355 327 Pfam PF00268 Ribonucleotide reductase, small chain 14 295 2.0E-67 T 11-11-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS03790 800ce661bda4d1b515d9f1d050c05355 327 SUPERFAMILY SSF47240 11 299 1.58E-81 T 11-11-2016 IPR009078 Ferritin-like superfamily TW_RS01220 2a2014bc5faac49fb5dc415291ac7df7 286 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 90 266 33.828 T 11-11-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TW_RS01220 2a2014bc5faac49fb5dc415291ac7df7 286 SUPERFAMILY SSF54768 112 179 5.86E-22 T 11-11-2016 TW_RS01220 2a2014bc5faac49fb5dc415291ac7df7 286 ProSitePatterns PS00585 Ribosomal protein S5 signature. 131 163 - T 11-11-2016 IPR018192 Ribosomal protein S5, N-terminal, conserved site TW_RS01220 2a2014bc5faac49fb5dc415291ac7df7 286 Gene3D G3DSA:3.30.160.20 113 175 2.4E-28 T 11-11-2016 IPR014720 Double-stranded RNA-binding domain TW_RS01220 2a2014bc5faac49fb5dc415291ac7df7 286 Pfam PF00333 Ribosomal protein S5, N-terminal domain 115 178 3.3E-27 T 11-11-2016 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 TW_RS01220 2a2014bc5faac49fb5dc415291ac7df7 286 SUPERFAMILY SSF54211 182 261 5.82E-24 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS01220 2a2014bc5faac49fb5dc415291ac7df7 286 Gene3D G3DSA:3.30.230.10 181 261 1.6E-31 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TW_RS01220 2a2014bc5faac49fb5dc415291ac7df7 286 Pfam PF03719 Ribosomal protein S5, C-terminal domain 190 260 7.1E-28 T 11-11-2016 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 TW_RS01220 2a2014bc5faac49fb5dc415291ac7df7 286 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 113 262 5.6E-65 T 11-11-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TW_RS01800 feb672199d7ddd0034f32968096bcb1b 271 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 41 264 1.4E-41 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 TW_RS01800 feb672199d7ddd0034f32968096bcb1b 271 PRINTS PR00123 ATP synthase A subunit signature 105 121 5.7E-17 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 TW_RS01800 feb672199d7ddd0034f32968096bcb1b 271 PRINTS PR00123 ATP synthase A subunit signature 189 211 5.7E-17 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 TW_RS01800 feb672199d7ddd0034f32968096bcb1b 271 PRINTS PR00123 ATP synthase A subunit signature 250 265 5.7E-17 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 TW_RS01800 feb672199d7ddd0034f32968096bcb1b 271 SUPERFAMILY SSF81336 96 263 2.22E-34 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 TW_RS01800 feb672199d7ddd0034f32968096bcb1b 271 Hamap MF_01393 ATP synthase subunit a [atpB]. 26 270 12.655 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 TW_RS01800 feb672199d7ddd0034f32968096bcb1b 271 Pfam PF00119 ATP synthase A chain 49 263 3.4E-44 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 TW_RS01800 feb672199d7ddd0034f32968096bcb1b 271 Gene3D G3DSA:1.20.120.220 97 267 1.8E-37 T 11-11-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 Reactome: R-HSA-163210 TW_RS02595 019ca5e8d941ec686ac912730839a039 241 Hamap MF_00201 DNA repair protein RecO [recO]. 3 240 22.669 T 11-11-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TW_RS02595 019ca5e8d941ec686ac912730839a039 241 TIGRFAM TIGR00613 reco: DNA repair protein RecO 6 237 8.5E-31 T 11-11-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TW_RS02595 019ca5e8d941ec686ac912730839a039 241 Pfam PF02565 Recombination protein O C terminal 91 234 5.2E-16 T 11-11-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 TW_RS02595 019ca5e8d941ec686ac912730839a039 241 SUPERFAMILY SSF50249 4 80 1.47E-17 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02595 019ca5e8d941ec686ac912730839a039 241 SUPERFAMILY SSF57863 84 229 1.26E-24 T 11-11-2016 TW_RS02595 019ca5e8d941ec686ac912730839a039 241 Pfam PF11967 Recombination protein O N terminal 5 80 5.0E-24 T 11-11-2016 IPR022572 DNA replication/recombination mediator RecO, N-terminal TW_RS02595 019ca5e8d941ec686ac912730839a039 241 Gene3D G3DSA:2.40.50.140 4 81 3.3E-28 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS03230 270843f8239d4d1fdb03d2c06ee3224d 259 Pfam PF01061 ABC-2 type transporter 14 208 5.7E-11 T 11-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TW_RS03230 270843f8239d4d1fdb03d2c06ee3224d 259 PIRSF PIRSF006648 2 252 2.2E-15 T 11-11-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 Gene3D G3DSA:3.40.50.720 5 236 1.4E-79 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 175 1.2E-5 T 11-11-2016 TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 235 1.8E-59 T 11-11-2016 TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 1.9E-10 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 1.9E-10 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 1.9E-10 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.3E-42 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.3E-42 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.3E-42 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.3E-42 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 1.3E-42 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.3E-42 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02445 66d98f7fc65afce5deefa6ab648c037f 238 SUPERFAMILY SSF51735 4 236 5.56E-77 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS01245 7a185b8baf13ac0a2d7b201f12a3f91e 287 Gene3D G3DSA:3.30.470.10 26 109 5.9E-14 T 11-11-2016 TW_RS01245 7a185b8baf13ac0a2d7b201f12a3f91e 287 Gene3D G3DSA:3.20.10.10 124 269 5.8E-31 T 11-11-2016 TW_RS01245 7a185b8baf13ac0a2d7b201f12a3f91e 287 SUPERFAMILY SSF56752 18 282 1.27E-51 T 11-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 TW_RS01245 7a185b8baf13ac0a2d7b201f12a3f91e 287 Pfam PF01063 Amino-transferase class IV 41 263 9.5E-40 T 11-11-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 TW_RS04150 710b3d86fe92c111177f30a3e0eb520f 296 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 17 289 16.477 T 11-11-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 TW_RS04150 710b3d86fe92c111177f30a3e0eb520f 296 Gene3D G3DSA:1.10.3730.10 187 251 2.5E-7 T 11-11-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TW_RS04150 710b3d86fe92c111177f30a3e0eb520f 296 SUPERFAMILY SSF51735 17 184 6.07E-20 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS04150 710b3d86fe92c111177f30a3e0eb520f 296 SUPERFAMILY SSF48179 187 268 3.06E-9 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TW_RS04150 710b3d86fe92c111177f30a3e0eb520f 296 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 187 289 2.0E-16 T 11-11-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TW_RS04150 710b3d86fe92c111177f30a3e0eb520f 296 PIRSF PIRSF000193 16 292 1.7E-82 T 11-11-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 TW_RS04150 710b3d86fe92c111177f30a3e0eb520f 296 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 18 122 2.9E-9 T 11-11-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TW_RS04150 710b3d86fe92c111177f30a3e0eb520f 296 Gene3D G3DSA:3.40.50.720 17 184 1.3E-33 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS02415 ac14d3f5cce6028cdbd0af1260259eef 322 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 14 56 3.3E-7 T 11-11-2016 TW_RS02415 ac14d3f5cce6028cdbd0af1260259eef 322 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 137 2.0E-7 T 11-11-2016 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 TW_RS02415 ac14d3f5cce6028cdbd0af1260259eef 322 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 198 269 1.8E-6 T 11-11-2016 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 TW_RS02415 ac14d3f5cce6028cdbd0af1260259eef 322 Gene3D G3DSA:3.10.330.20 18 68 5.1E-12 T 11-11-2016 TW_RS02415 ac14d3f5cce6028cdbd0af1260259eef 322 Gene3D G3DSA:3.40.50.150 70 300 7.3E-47 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS02415 ac14d3f5cce6028cdbd0af1260259eef 322 SUPERFAMILY SSF53335 176 289 1.5E-49 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS02415 ac14d3f5cce6028cdbd0af1260259eef 322 SUPERFAMILY SSF53335 9 149 1.5E-49 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS02415 ac14d3f5cce6028cdbd0af1260259eef 322 PIRSF PIRSF017269 2 301 2.5E-93 T 11-11-2016 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 209 321 3.7E-14 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 2.0E-15 T 11-11-2016 IPR004176 Clp, N-terminal GO:0019538 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 141 5.2E-14 T 11-11-2016 IPR004176 Clp, N-terminal GO:0019538 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 Gene3D G3DSA:1.10.8.60 351 430 1.8E-33 T 11-11-2016 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 SUPERFAMILY SSF81923 3 144 1.02E-30 T 11-11-2016 IPR004176 Clp, N-terminal GO:0019538 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 619 637 1.1E-40 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 545 563 1.1E-40 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 590 608 1.1E-40 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 652 666 1.1E-40 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 SMART SM01086 718 807 1.7E-31 T 11-11-2016 IPR019489 Clp ATPase, C-terminal TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 SUPERFAMILY SSF52540 165 461 1.65E-74 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 SMART SM00382 541 680 1.7E-13 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 SMART SM00382 204 344 1.9E-10 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 718 797 3.8E-24 T 11-11-2016 IPR019489 Clp ATPase, C-terminal TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 Gene3D G3DSA:3.40.50.300 167 347 4.6E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 Pfam PF07724 AAA domain (Cdc48 subfamily) 540 712 9.7E-51 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 Gene3D G3DSA:1.10.8.60 730 808 7.5E-28 T 11-11-2016 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 SUPERFAMILY SSF52540 490 797 9.81E-78 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 Gene3D G3DSA:1.10.1780.10 1 145 1.9E-49 T 11-11-2016 IPR004176 Clp, N-terminal GO:0019538 TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 Gene3D G3DSA:3.40.50.300 495 667 7.1E-55 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00370 93843b98b80a15d0dad6a2e82fe60da8 836 Gene3D G3DSA:3.40.50.300 701 729 7.1E-55 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03585 d57a8be50c87b52d43127aa909ab7924 356 Gene3D G3DSA:3.30.1360.120 5 55 6.2E-43 T 11-11-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TW_RS03585 d57a8be50c87b52d43127aa909ab7924 356 Gene3D G3DSA:3.30.1360.120 144 237 6.2E-43 T 11-11-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TW_RS03585 d57a8be50c87b52d43127aa909ab7924 356 SUPERFAMILY SSF103025 4 262 4.4E-74 T 11-11-2016 TW_RS03585 d57a8be50c87b52d43127aa909ab7924 356 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 259 2.6E-80 T 11-11-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal TW_RS03585 d57a8be50c87b52d43127aa909ab7924 356 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 7 356 8.8E-87 T 11-11-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TW_RS03585 d57a8be50c87b52d43127aa909ab7924 356 SUPERFAMILY SSF101790 275 355 2.45E-24 T 11-11-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain TW_RS03585 d57a8be50c87b52d43127aa909ab7924 356 PIRSF PIRSF006487 1 356 2.8E-75 T 11-11-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TW_RS03585 d57a8be50c87b52d43127aa909ab7924 356 Gene3D G3DSA:2.40.30.110 280 356 3.4E-26 T 11-11-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TW_RS03585 d57a8be50c87b52d43127aa909ab7924 356 Gene3D G3DSA:3.30.70.1400 56 135 1.7E-20 T 11-11-2016 TW_RS03585 d57a8be50c87b52d43127aa909ab7924 356 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 279 351 1.4E-16 T 11-11-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 Pfam PF00271 Helicase conserved C-terminal domain 435 548 1.4E-18 T 11-11-2016 IPR001650 Helicase, C-terminal TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 Pfam PF12344 Ultra-violet resistance protein B 555 596 1.4E-19 T 11-11-2016 IPR024759 UvrB, YAD/RRR-motif-containing domain TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 Gene3D G3DSA:3.40.50.300 392 413 8.0E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 Gene3D G3DSA:3.40.50.300 11 94 8.0E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 Gene3D G3DSA:3.40.50.300 282 342 8.0E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 SUPERFAMILY SSF46600 625 665 1.24E-10 T 11-11-2016 IPR001943 UVR domain GO:0005515 TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 SMART SM00490 463 549 4.5E-20 T 11-11-2016 IPR001650 Helicase, C-terminal TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 SUPERFAMILY SSF52540 38 85 6.93E-34 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 SUPERFAMILY SSF52540 473 594 6.93E-34 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 Gene3D G3DSA:4.10.860.10 625 666 1.7E-15 T 11-11-2016 IPR001943 UVR domain GO:0005515 TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 Gene3D G3DSA:3.40.50.300 422 584 3.3E-37 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 Hamap MF_00204 UvrABC system protein B [uvrB]. 8 664 41.851 T 11-11-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 Pfam PF04851 Type III restriction enzyme, res subunit 21 97 5.2E-9 T 11-11-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 10 662 0.0 T 11-11-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 SMART SM00487 14 429 7.0E-23 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 Pfam PF02151 UvrB/uvrC motif 632 663 9.6E-8 T 11-11-2016 IPR001943 UVR domain GO:0005515 TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 SUPERFAMILY SSF52540 8 418 5.05E-129 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02530 7a7b934e8cf37d551bfd6662c878c8b9 677 Gene3D G3DSA:3.30.2060.10 165 228 1.5E-9 T 11-11-2016 TW_RS04210 6defec35ca929790067e3d5556970a16 267 Pfam PF00535 Glycosyl transferase family 2 10 172 2.6E-27 T 11-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TW_RS04210 6defec35ca929790067e3d5556970a16 267 SUPERFAMILY SSF53448 10 220 3.94E-39 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS04210 6defec35ca929790067e3d5556970a16 267 Gene3D G3DSA:3.90.550.10 10 206 1.7E-22 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS04185 6f315c7ad7b72cbed685b9ff9581b71b 323 Pfam PF01578 Cytochrome C assembly protein 117 318 2.1E-38 T 11-11-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TW_RS04185 6f315c7ad7b72cbed685b9ff9581b71b 323 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 95 321 3.5E-67 T 11-11-2016 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 TW_RS03070 6b0884570198cca4304322cb0c71fad9 766 Gene3D G3DSA:3.40.50.300 1 219 9.4E-63 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03070 6b0884570198cca4304322cb0c71fad9 766 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS03070 6b0884570198cca4304322cb0c71fad9 766 SMART SM00382 28 215 1.9E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS03070 6b0884570198cca4304322cb0c71fad9 766 Pfam PF00005 ABC transporter 19 166 5.5E-31 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS03070 6b0884570198cca4304322cb0c71fad9 766 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 2.3E-83 T 11-11-2016 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 TW_RS03070 6b0884570198cca4304322cb0c71fad9 766 SUPERFAMILY SSF52540 1 221 1.64E-63 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 SUPERFAMILY SSF52374 424 663 1.04E-124 T 11-11-2016 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 SUPERFAMILY SSF52374 22 213 1.04E-124 T 11-11-2016 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 SUPERFAMILY SSF47323 686 905 4.11E-38 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 Gene3D G3DSA:1.10.730.10 677 851 8.5E-36 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 17 1041 13.319 T 11-11-2016 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 33 666 3.1E-169 T 11-11-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 Gene3D G3DSA:3.90.740.10 221 410 5.9E-49 T 11-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 SUPERFAMILY SSF47323 969 1043 3.53E-5 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 Gene3D G3DSA:3.40.50.620 23 209 7.3E-136 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 Gene3D G3DSA:3.40.50.620 427 663 7.3E-136 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 Pfam PF08264 Anticodon-binding domain of tRNA 720 860 4.3E-25 T 11-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 SUPERFAMILY SSF50677 221 424 2.35E-42 T 11-11-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 246 269 1.3E-28 T 11-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 422 437 1.3E-28 T 11-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 591 600 1.3E-28 T 11-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 551 564 1.3E-28 T 11-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 56 67 1.3E-28 T 11-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TW_RS01545 933a29763edebcee2fbcab8d383d0725 1056 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 23 866 1.8E-237 T 11-11-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 144 1.5E-33 T 11-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 449 42.504 T 11-11-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 445 6.7E-160 T 11-11-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Gene3D G3DSA:3.40.120.10 182 256 6.2E-21 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 SUPERFAMILY SSF53738 165 262 2.47E-23 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 104 113 - T 11-11-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Gene3D G3DSA:3.30.310.50 368 446 1.1E-11 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Gene3D G3DSA:3.40.120.10 4 157 9.9E-37 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 408 438 9.0E-8 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 SUPERFAMILY SSF55957 364 450 1.44E-15 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 166 260 8.7E-15 T 11-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 SUPERFAMILY SSF53738 264 370 3.37E-30 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 372 2.7E-33 T 11-11-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 Gene3D G3DSA:3.40.120.10 257 367 3.4E-34 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 SUPERFAMILY SSF53738 4 187 4.71E-40 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 180 199 1.0E-12 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 103 117 1.0E-12 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00835 d90f7639b2e013ef46b7cd87c3ac0fbc 453 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 240 255 1.0E-12 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS01785 9d2618038422ed4deae61160f6ab6306 225 Pfam PF01300 Telomere recombination 22 181 2.2E-38 T 11-11-2016 IPR006070 YrdC-like domain GO:0003725 TW_RS01785 9d2618038422ed4deae61160f6ab6306 225 Gene3D G3DSA:3.90.870.10 13 219 2.7E-48 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TW_RS01785 9d2618038422ed4deae61160f6ab6306 225 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 14 181 3.3E-39 T 11-11-2016 IPR006070 YrdC-like domain GO:0003725 TW_RS01785 9d2618038422ed4deae61160f6ab6306 225 SUPERFAMILY SSF55821 3 181 3.36E-44 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TW_RS01430 83b2c7eb7d3f96be1c69c72df3f0b5fb 259 SUPERFAMILY SSF52317 18 197 7.56E-12 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS01430 83b2c7eb7d3f96be1c69c72df3f0b5fb 259 Gene3D G3DSA:3.40.50.880 18 202 1.5E-6 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS01430 83b2c7eb7d3f96be1c69c72df3f0b5fb 259 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 37 186 5.2E-8 T 11-11-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 TW_RS01425 b40910c4a297167924987ec59e104f05 461 Gene3D G3DSA:3.40.1190.10 42 266 8.9E-32 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS01425 b40910c4a297167924987ec59e104f05 461 Pfam PF08245 Mur ligase middle domain 52 262 1.2E-14 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS01425 b40910c4a297167924987ec59e104f05 461 SUPERFAMILY SSF53623 38 266 2.18E-29 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS02395 301f723dde68341cbf382681540dd0de 258 Gene3D G3DSA:3.40.50.720 14 168 1.4E-22 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS02395 301f723dde68341cbf382681540dd0de 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 1.8E-5 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02395 301f723dde68341cbf382681540dd0de 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.8E-5 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02395 301f723dde68341cbf382681540dd0de 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 1.8E-5 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02395 301f723dde68341cbf382681540dd0de 258 Pfam PF00106 short chain dehydrogenase 17 148 4.2E-16 T 11-11-2016 IPR002347 Short-chain dehydrogenase/reductase SDR TW_RS02395 301f723dde68341cbf382681540dd0de 258 SUPERFAMILY SSF51735 11 155 2.38E-24 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS03440 d7987e52b412d63f8495a4cf9a500cce 538 PIRSF PIRSF004803 1 538 1.4E-181 T 11-11-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 TW_RS03440 d7987e52b412d63f8495a4cf9a500cce 538 Pfam PF12706 Beta-lactamase superfamily domain 23 165 1.6E-12 T 11-11-2016 IPR001279 Metallo-beta-lactamase TW_RS03440 d7987e52b412d63f8495a4cf9a500cce 538 SUPERFAMILY SSF56281 2 412 5.13E-86 T 11-11-2016 IPR001279 Metallo-beta-lactamase TW_RS03440 d7987e52b412d63f8495a4cf9a500cce 538 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 348 396 1.8E-5 T 11-11-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TW_RS03440 d7987e52b412d63f8495a4cf9a500cce 538 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 1 535 1.1E-131 T 11-11-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 TW_RS03440 d7987e52b412d63f8495a4cf9a500cce 538 SMART SM00849 10 204 1.9E-22 T 11-11-2016 IPR001279 Metallo-beta-lactamase TW_RS03440 d7987e52b412d63f8495a4cf9a500cce 538 Gene3D G3DSA:3.60.15.10 2 244 6.4E-71 T 11-11-2016 IPR001279 Metallo-beta-lactamase TW_RS02165 ed2a1d474f586107e5160a6ed063a2a8 303 SMART SM00934 17 284 3.2E-9 T 11-11-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS02165 ed2a1d474f586107e5160a6ed063a2a8 303 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 164 1.9E-22 T 11-11-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS02165 ed2a1d474f586107e5160a6ed063a2a8 303 Gene3D G3DSA:3.20.20.70 6 278 1.3E-37 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS02165 ed2a1d474f586107e5160a6ed063a2a8 303 SUPERFAMILY SSF51366 3 278 9.42E-45 T 11-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TW_RS02165 ed2a1d474f586107e5160a6ed063a2a8 303 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 4 286 1.2E-97 T 11-11-2016 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686 TW_RS00420 b2b55e5db50ff4ce2aab8b77884de3c5 98 SMART SM00883 4 96 8.5E-51 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TW_RS00420 b2b55e5db50ff4ce2aab8b77884de3c5 98 ProSitePatterns PS00681 Chaperonins cpn10 signature. 5 29 - T 11-11-2016 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 TW_RS00420 b2b55e5db50ff4ce2aab8b77884de3c5 98 PRINTS PR00297 10kDa chaperonin signature 5 20 2.5E-29 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TW_RS00420 b2b55e5db50ff4ce2aab8b77884de3c5 98 PRINTS PR00297 10kDa chaperonin signature 62 74 2.5E-29 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TW_RS00420 b2b55e5db50ff4ce2aab8b77884de3c5 98 PRINTS PR00297 10kDa chaperonin signature 27 48 2.5E-29 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TW_RS00420 b2b55e5db50ff4ce2aab8b77884de3c5 98 PRINTS PR00297 10kDa chaperonin signature 83 96 2.5E-29 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TW_RS00420 b2b55e5db50ff4ce2aab8b77884de3c5 98 Gene3D G3DSA:2.30.33.40 5 96 6.7E-37 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TW_RS00420 b2b55e5db50ff4ce2aab8b77884de3c5 98 SUPERFAMILY SSF50129 3 97 2.77E-33 T 11-11-2016 IPR011032 GroES-like TW_RS00420 b2b55e5db50ff4ce2aab8b77884de3c5 98 Pfam PF00166 Chaperonin 10 Kd subunit 5 96 1.8E-33 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TW_RS00420 b2b55e5db50ff4ce2aab8b77884de3c5 98 Hamap MF_00580 10 kDa chaperonin [groS]. 4 97 24.98 T 11-11-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 Gene3D G3DSA:3.90.550.10 165 260 2.1E-75 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 Gene3D G3DSA:3.90.550.10 346 406 2.1E-75 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 Gene3D G3DSA:3.90.550.10 12 105 2.1E-75 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 14 607 31.208 T 11-11-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 473 506 3.7E-7 T 11-11-2016 IPR001451 Hexapeptide repeat TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 425 455 2.4E-4 T 11-11-2016 IPR001451 Hexapeptide repeat TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 552 583 2.6E-4 T 11-11-2016 IPR001451 Hexapeptide repeat TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 SUPERFAMILY SSF51161 412 591 3.17E-42 T 11-11-2016 IPR011004 Trimeric LpxA-like TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 SUPERFAMILY SSF53448 169 259 2.94E-28 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 SUPERFAMILY SSF53448 15 108 2.94E-28 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 Pfam PF12804 MobA-like NTP transferase domain 18 205 8.1E-14 T 11-11-2016 IPR025877 MobA-like NTP transferase TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 Gene3D G3DSA:2.160.10.10 411 591 8.6E-43 T 11-11-2016 TW_RS03195 f8e6b653738887f4d908280f36a440fa 611 SUPERFAMILY SSF53448 323 439 9.14E-6 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS03065 5f331df97ed54d12400f7f0477d5262a 303 Pfam PF02687 FtsX-like permease family 183 302 6.9E-9 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 TW_RS03065 5f331df97ed54d12400f7f0477d5262a 303 PIRSF PIRSF003097 1 303 2.0E-59 T 11-11-2016 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 TW_RS04180 abe8d006179f6bf459b67e9dda384d00 541 Pfam PF05140 ResB-like family 15 511 8.4E-108 T 11-11-2016 IPR007816 ResB-like domain TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 Gene3D G3DSA:2.40.50.140 64 126 1.7E-21 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 SMART SM01185 67 121 1.1E-21 T 11-11-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 PIRSF PIRSF005901 1 185 1.6E-60 T 11-11-2016 IPR020599 Translation elongation factor P/YeiP TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 SUPERFAMILY SSF50104 2 60 2.59E-19 T 11-11-2016 IPR008991 Translation protein SH3-like domain TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 Gene3D G3DSA:2.30.30.30 3 60 6.2E-29 T 11-11-2016 IPR014722 Ribosomal protein L2 domain 2 TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 11-11-2016 IPR013852 Translation elongation factor P/YeiP, conserved site TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 SMART SM00841 129 184 3.5E-29 T 11-11-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 2.2E-18 T 11-11-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 Pfam PF09285 Elongation factor P, C-terminal 129 183 2.1E-23 T 11-11-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 Gene3D G3DSA:2.40.50.140 129 185 3.6E-25 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 44.082 T 11-11-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 SUPERFAMILY SSF50249 65 126 2.91E-15 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 2.4E-72 T 11-11-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 4.1E-26 T 11-11-2016 IPR013185 Translation elongation factor, KOW-like TW_RS02145 ade5932a1d00c7a9df30c72bf596150a 185 SUPERFAMILY SSF50249 129 185 1.1E-15 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS04200 75d380862513118c153037d28be398f6 583 Pfam PF08264 Anticodon-binding domain of tRNA 460 550 8.2E-7 T 11-11-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 TW_RS04200 75d380862513118c153037d28be398f6 583 PRINTS PR01041 Methionyl-tRNA synthetase signature 5 18 9.4E-21 T 11-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TW_RS04200 75d380862513118c153037d28be398f6 583 PRINTS PR01041 Methionyl-tRNA synthetase signature 37 51 9.4E-21 T 11-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TW_RS04200 75d380862513118c153037d28be398f6 583 PRINTS PR01041 Methionyl-tRNA synthetase signature 330 345 9.4E-21 T 11-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TW_RS04200 75d380862513118c153037d28be398f6 583 PRINTS PR01041 Methionyl-tRNA synthetase signature 422 433 9.4E-21 T 11-11-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TW_RS04200 75d380862513118c153037d28be398f6 583 Gene3D G3DSA:3.40.50.620 321 408 1.0E-63 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS04200 75d380862513118c153037d28be398f6 583 Gene3D G3DSA:3.40.50.620 3 112 1.0E-63 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS04200 75d380862513118c153037d28be398f6 583 Gene3D G3DSA:3.40.50.620 249 267 1.0E-63 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS04200 75d380862513118c153037d28be398f6 583 Gene3D G3DSA:1.10.730.10 413 580 5.6E-36 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS04200 75d380862513118c153037d28be398f6 583 SUPERFAMILY SSF52374 169 270 2.71E-99 T 11-11-2016 TW_RS04200 75d380862513118c153037d28be398f6 583 SUPERFAMILY SSF52374 3 137 2.71E-99 T 11-11-2016 TW_RS04200 75d380862513118c153037d28be398f6 583 SUPERFAMILY SSF52374 319 424 2.71E-99 T 11-11-2016 TW_RS04200 75d380862513118c153037d28be398f6 583 Gene3D G3DSA:2.170.220.10 115 248 5.6E-42 T 11-11-2016 TW_RS04200 75d380862513118c153037d28be398f6 583 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 580 41.181 T 11-11-2016 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TW_RS04200 75d380862513118c153037d28be398f6 583 SUPERFAMILY SSF47323 423 580 6.17E-31 T 11-11-2016 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS04200 75d380862513118c153037d28be398f6 583 Pfam PF09334 tRNA synthetases class I (M) 316 434 9.3E-37 T 11-11-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS04200 75d380862513118c153037d28be398f6 583 Pfam PF09334 tRNA synthetases class I (M) 3 263 1.1E-63 T 11-11-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 Pfam PF07724 AAA domain (Cdc48 subfamily) 440 600 1.1E-46 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 550 564 3.5E-39 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 517 535 3.5E-39 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 445 463 3.5E-39 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 488 506 3.5E-39 T 11-11-2016 IPR001270 ClpA/B family GO:0005524 TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 606 684 2.8E-24 T 11-11-2016 IPR019489 Clp ATPase, C-terminal TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 SUPERFAMILY SSF52540 7 389 6.56E-89 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 Gene3D G3DSA:3.40.50.300 7 186 5.9E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 Gene3D G3DSA:3.40.50.300 394 616 4.4E-54 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 Gene3D G3DSA:1.10.8.60 189 271 4.2E-34 T 11-11-2016 TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 SMART SM01086 606 695 2.8E-30 T 11-11-2016 IPR019489 Clp ATPase, C-terminal TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 473 491 - T 11-11-2016 IPR028299 ClpA/B, conserved site 2 TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 Gene3D G3DSA:1.10.8.60 617 694 2.0E-27 T 11-11-2016 TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 139 151 - T 11-11-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 50 181 7.9E-14 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 SUPERFAMILY SSF52540 390 684 6.17E-72 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 SMART SM00382 441 607 5.0E-12 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS04120 e5d7c189b72a674a0fe805c01d7a526d 699 SMART SM00382 45 188 1.2E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00760 10a85fa1ea0a01c202e05fccfab79ac0 526 SUPERFAMILY SSF53850 30 524 1.99E-92 T 11-11-2016 TW_RS00760 10a85fa1ea0a01c202e05fccfab79ac0 526 PIRSF PIRSF002741 27 521 3.9E-62 T 11-11-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TW_RS00760 10a85fa1ea0a01c202e05fccfab79ac0 526 Gene3D G3DSA:3.40.190.10 194 310 2.9E-21 T 11-11-2016 TW_RS00760 10a85fa1ea0a01c202e05fccfab79ac0 526 Gene3D G3DSA:3.90.76.10 44 193 1.1E-34 T 11-11-2016 TW_RS00760 10a85fa1ea0a01c202e05fccfab79ac0 526 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 448 3.6E-58 T 11-11-2016 IPR000914 Solute-binding protein family 5 domain TW_RS00760 10a85fa1ea0a01c202e05fccfab79ac0 526 Gene3D G3DSA:3.10.105.10 311 496 3.4E-39 T 11-11-2016 TW_RS03830 d1f35d155e638beed0461e9651b42295 211 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 24 209 2.4E-65 T 11-11-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 TW_RS03830 d1f35d155e638beed0461e9651b42295 211 SUPERFAMILY SSF142695 22 187 1.96E-54 T 11-11-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 TW_RS03830 d1f35d155e638beed0461e9651b42295 211 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 20 211 35.726 T 11-11-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 TW_RS03830 d1f35d155e638beed0461e9651b42295 211 Pfam PF00925 GTP cyclohydrolase II 24 183 8.2E-61 T 11-11-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 TW_RS01965 e011ce11a0f128f5f11b06e46fdde61c 158 Gene3D G3DSA:3.10.129.10 5 157 9.5E-40 T 11-11-2016 IPR029069 HotDog domain TW_RS01965 e011ce11a0f128f5f11b06e46fdde61c 158 SUPERFAMILY SSF54637 5 157 1.34E-24 T 11-11-2016 IPR029069 HotDog domain TW_RS01965 e011ce11a0f128f5f11b06e46fdde61c 158 Pfam PF03061 Thioesterase superfamily 15 121 2.0E-11 T 11-11-2016 IPR006683 Thioesterase domain Reactome: R-HSA-75105 TW_RS01710 df5cfa92f3e5533b8d30744fca78efd9 231 Hamap MF_01220_B Uridylate kinase [pyrH]. 1 230 38.351 T 11-11-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 TW_RS01710 df5cfa92f3e5533b8d30744fca78efd9 231 PIRSF PIRSF005650 1 231 3.3E-79 T 11-11-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TW_RS01710 df5cfa92f3e5533b8d30744fca78efd9 231 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 4 226 4.7E-81 T 11-11-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 TW_RS01710 df5cfa92f3e5533b8d30744fca78efd9 231 Pfam PF00696 Amino acid kinase family 5 211 7.2E-27 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase TW_RS01710 df5cfa92f3e5533b8d30744fca78efd9 231 SUPERFAMILY SSF53633 3 228 1.1E-59 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase TW_RS01710 df5cfa92f3e5533b8d30744fca78efd9 231 Gene3D G3DSA:3.40.1160.10 3 227 1.2E-72 T 11-11-2016 IPR001048 Aspartate/glutamate/uridylate kinase TW_RS04270 3f1bd0298c273cb8c9ba6e6796070529 485 SUPERFAMILY SSF56601 150 483 1.26E-83 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like TW_RS04270 3f1bd0298c273cb8c9ba6e6796070529 485 Pfam PF00905 Penicillin binding protein transpeptidase domain 167 479 1.1E-61 T 11-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TW_RS04270 3f1bd0298c273cb8c9ba6e6796070529 485 SUPERFAMILY SSF56519 89 131 4.32E-6 T 11-11-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TW_RS04270 3f1bd0298c273cb8c9ba6e6796070529 485 Gene3D G3DSA:3.90.1310.10 89 155 6.9E-9 T 11-11-2016 TW_RS04270 3f1bd0298c273cb8c9ba6e6796070529 485 Gene3D G3DSA:3.40.710.10 156 483 3.8E-92 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like TW_RS00910 1708a1604bc897f7980107fb4493322c 796 Pfam PF05345 Putative Ig domain 638 682 6.8E-8 T 11-11-2016 IPR008009 Putative Ig TW_RS00910 1708a1604bc897f7980107fb4493322c 796 Pfam PF05345 Putative Ig domain 727 774 1.3E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS00910 1708a1604bc897f7980107fb4493322c 796 Pfam PF05345 Putative Ig domain 399 436 8.2E-13 T 11-11-2016 IPR008009 Putative Ig TW_RS00910 1708a1604bc897f7980107fb4493322c 796 Pfam PF07861 WisP family N-Terminal Region 37 275 9.8E-157 T 11-11-2016 IPR012503 WisP, N-terminal TW_RS02885 3a1fc11811769d8c930a04aa8d6527bf 480 Gene3D G3DSA:3.40.50.720 13 103 1.6E-15 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS02885 3a1fc11811769d8c930a04aa8d6527bf 480 SUPERFAMILY SSF53623 119 335 6.67E-39 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS02885 3a1fc11811769d8c930a04aa8d6527bf 480 Gene3D G3DSA:3.90.190.20 339 473 1.4E-38 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02885 3a1fc11811769d8c930a04aa8d6527bf 480 Pfam PF01225 Mur ligase family, catalytic domain 19 105 1.2E-4 T 11-11-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TW_RS02885 3a1fc11811769d8c930a04aa8d6527bf 480 SUPERFAMILY SSF53244 339 476 1.83E-36 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02885 3a1fc11811769d8c930a04aa8d6527bf 480 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 123 146 - T 11-11-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 TW_RS02885 3a1fc11811769d8c930a04aa8d6527bf 480 Gene3D G3DSA:3.40.1190.10 105 335 6.2E-47 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS02885 3a1fc11811769d8c930a04aa8d6527bf 480 Pfam PF02875 Mur ligase family, glutamate ligase domain 339 407 4.5E-8 T 11-11-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TW_RS02885 3a1fc11811769d8c930a04aa8d6527bf 480 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 17 476 28.917 T 11-11-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS02885 3a1fc11811769d8c930a04aa8d6527bf 480 Pfam PF08245 Mur ligase middle domain 125 260 5.5E-20 T 11-11-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 TW_RS02885 3a1fc11811769d8c930a04aa8d6527bf 480 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 20 474 3.1E-102 T 11-11-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS02885 3a1fc11811769d8c930a04aa8d6527bf 480 SUPERFAMILY SSF51984 13 104 3.27E-15 T 11-11-2016 TW_RS00595 c8c4ebe8384ef3868a14b126376592b5 545 PIRSF PIRSF003128 1 540 6.0E-130 T 11-11-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 TW_RS00595 c8c4ebe8384ef3868a14b126376592b5 545 Gene3D G3DSA:3.40.50.300 401 499 4.6E-10 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00595 c8c4ebe8384ef3868a14b126376592b5 545 SUPERFAMILY SSF52540 1 209 4.85E-42 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00595 c8c4ebe8384ef3868a14b126376592b5 545 SMART SM00382 21 496 5.2E-4 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00595 c8c4ebe8384ef3868a14b126376592b5 545 Gene3D G3DSA:3.40.50.300 1 198 1.0E-36 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00595 c8c4ebe8384ef3868a14b126376592b5 545 SUPERFAMILY SSF52540 265 502 7.45E-27 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00595 c8c4ebe8384ef3868a14b126376592b5 545 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 494 4.9E-19 T 11-11-2016 IPR003395 RecF/RecN/SMC, N-terminal TW_RS02400 1ecb91c34dc8f1d9fb4e59f43db9e160 240 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 81 99 3.7E-17 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TW_RS02400 1ecb91c34dc8f1d9fb4e59f43db9e160 240 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 149 177 3.7E-17 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TW_RS02400 1ecb91c34dc8f1d9fb4e59f43db9e160 240 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 2 29 3.7E-17 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TW_RS02400 1ecb91c34dc8f1d9fb4e59f43db9e160 240 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 99 125 3.7E-17 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TW_RS02400 1ecb91c34dc8f1d9fb4e59f43db9e160 240 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 1 236 12.841 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TW_RS02400 1ecb91c34dc8f1d9fb4e59f43db9e160 240 Pfam PF00902 Sec-independent protein translocase protein (TatC) 6 217 6.0E-41 T 11-11-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TW_RS02400 1ecb91c34dc8f1d9fb4e59f43db9e160 240 TIGRFAM TIGR01912 TatC-Arch: Sec-independent protein translocase TatC 3 234 4.8E-77 T 11-11-2016 IPR011532 Sec-independent protein translocase TatC, archaeal TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 SUPERFAMILY SSF53955 70 146 2.47E-55 T 11-11-2016 IPR023346 Lysozyme-like domain TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 SUPERFAMILY SSF53955 193 323 2.47E-55 T 11-11-2016 IPR023346 Lysozyme-like domain TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 Pfam PF03793 PASTA domain 748 807 1.1E-11 T 11-11-2016 IPR005543 PASTA domain TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 Pfam PF03793 PASTA domain 814 874 3.2E-13 T 11-11-2016 IPR005543 PASTA domain TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 SMART SM00740 810 874 1.9E-11 T 11-11-2016 IPR005543 PASTA domain TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 SMART SM00740 745 809 1.9E-10 T 11-11-2016 IPR005543 PASTA domain TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 Gene3D G3DSA:3.40.710.10 301 742 1.9E-83 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 Pfam PF00912 Transglycosylase 70 298 2.5E-48 T 11-11-2016 IPR001264 Glycosyl transferase, family 51 TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 SUPERFAMILY SSF56601 284 302 3.17E-67 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 SUPERFAMILY SSF56601 335 750 3.17E-67 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 Gene3D G3DSA:1.10.3810.10 193 300 5.2E-61 T 11-11-2016 TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 Gene3D G3DSA:1.10.3810.10 69 146 5.2E-61 T 11-11-2016 TW_RS03900 1c529b58e0b11ec05e4b7ce656b61a7f 876 Pfam PF00905 Penicillin binding protein transpeptidase domain 401 676 5.6E-14 T 11-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TW_RS01915 a6d3b13afbf2457f3f44985f67b76058 242 Pfam PF02361 Cobalt transport protein 14 204 1.4E-5 T 11-11-2016 IPR003339 ABC/ECF transporter, transmembrane component TW_RS04135 c6ae3593d233b5419ab356ba946bee06 189 PRINTS PR00773 GrpE protein signature 138 153 2.9E-14 T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TW_RS04135 c6ae3593d233b5419ab356ba946bee06 189 PRINTS PR00773 GrpE protein signature 165 184 2.9E-14 T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TW_RS04135 c6ae3593d233b5419ab356ba946bee06 189 PRINTS PR00773 GrpE protein signature 91 106 2.9E-14 T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TW_RS04135 c6ae3593d233b5419ab356ba946bee06 189 PRINTS PR00773 GrpE protein signature 63 79 2.9E-14 T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TW_RS04135 c6ae3593d233b5419ab356ba946bee06 189 ProSitePatterns PS01071 grpE protein signature. 141 184 - T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TW_RS04135 c6ae3593d233b5419ab356ba946bee06 189 Pfam PF01025 GrpE 35 185 1.5E-28 T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TW_RS04135 c6ae3593d233b5419ab356ba946bee06 189 Gene3D G3DSA:2.30.22.10 130 185 1.0E-18 T 11-11-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TW_RS04135 c6ae3593d233b5419ab356ba946bee06 189 Gene3D G3DSA:3.90.20.20 52 125 9.1E-10 T 11-11-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 TW_RS04135 c6ae3593d233b5419ab356ba946bee06 189 SUPERFAMILY SSF58014 52 130 3.01E-9 T 11-11-2016 TW_RS04135 c6ae3593d233b5419ab356ba946bee06 189 Hamap MF_01151 Protein GrpE [grpE]. 5 186 14.612 T 11-11-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TW_RS04135 c6ae3593d233b5419ab356ba946bee06 189 SUPERFAMILY SSF51064 132 185 1.1E-14 T 11-11-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TW_RS01525 9f9066062575b8f864003c9816621ed4 180 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 180 34.872 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TW_RS01525 9f9066062575b8f864003c9816621ed4 180 Gene3D G3DSA:3.90.226.10 3 178 4.3E-71 T 11-11-2016 IPR029045 ClpP/crotonase-like domain TW_RS01525 9f9066062575b8f864003c9816621ed4 180 SUPERFAMILY SSF52096 6 179 5.68E-62 T 11-11-2016 IPR029045 ClpP/crotonase-like domain TW_RS01525 9f9066062575b8f864003c9816621ed4 180 PRINTS PR00127 Clp protease catalytic subunit P signature 78 95 7.9E-44 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TW_RS01525 9f9066062575b8f864003c9816621ed4 180 PRINTS PR00127 Clp protease catalytic subunit P signature 7 22 7.9E-44 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TW_RS01525 9f9066062575b8f864003c9816621ed4 180 PRINTS PR00127 Clp protease catalytic subunit P signature 99 118 7.9E-44 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TW_RS01525 9f9066062575b8f864003c9816621ed4 180 PRINTS PR00127 Clp protease catalytic subunit P signature 156 175 7.9E-44 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TW_RS01525 9f9066062575b8f864003c9816621ed4 180 PRINTS PR00127 Clp protease catalytic subunit P signature 47 67 7.9E-44 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TW_RS01525 9f9066062575b8f864003c9816621ed4 180 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 100 113 - T 11-11-2016 IPR033135 ClpP, histidine active site TW_RS01525 9f9066062575b8f864003c9816621ed4 180 Pfam PF00574 Clp protease 3 178 3.5E-72 T 11-11-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TW_RS00790 014cb921d43cc104372250a2f8bf3690 542 SUPERFAMILY SSF52540 8 259 8.05E-62 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00790 014cb921d43cc104372250a2f8bf3690 542 Gene3D G3DSA:3.40.50.300 7 261 9.3E-69 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00790 014cb921d43cc104372250a2f8bf3690 542 Gene3D G3DSA:3.40.50.300 282 532 1.4E-74 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00790 014cb921d43cc104372250a2f8bf3690 542 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS00790 014cb921d43cc104372250a2f8bf3690 542 SUPERFAMILY SSF52540 285 530 1.21E-67 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00790 014cb921d43cc104372250a2f8bf3690 542 Pfam PF00005 ABC transporter 29 188 1.2E-27 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS00790 014cb921d43cc104372250a2f8bf3690 542 Pfam PF00005 ABC transporter 308 458 2.8E-30 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS00790 014cb921d43cc104372250a2f8bf3690 542 SMART SM00382 316 508 2.8E-17 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00790 014cb921d43cc104372250a2f8bf3690 542 SMART SM00382 37 237 1.0E-16 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00790 014cb921d43cc104372250a2f8bf3690 542 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 510 535 3.5E-4 T 11-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TW_RS00790 014cb921d43cc104372250a2f8bf3690 542 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 271 2.3E-6 T 11-11-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TW_RS00790 014cb921d43cc104372250a2f8bf3690 542 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS04265 6182fea61adf6b5d460110cb704bd2fb 448 Pfam PF01098 Cell cycle protein 80 438 4.1E-67 T 11-11-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 TW_RS03810 71ce2740f7bd9f7a8f70da551ae61dad 335 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 20 30 - T 11-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS03810 71ce2740f7bd9f7a8f70da551ae61dad 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 75 94 6.8E-25 T 11-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TW_RS03810 71ce2740f7bd9f7a8f70da551ae61dad 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 25 41 6.8E-25 T 11-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TW_RS03810 71ce2740f7bd9f7a8f70da551ae61dad 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 201 211 6.8E-25 T 11-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TW_RS03810 71ce2740f7bd9f7a8f70da551ae61dad 335 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 150 171 6.8E-25 T 11-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TW_RS03810 71ce2740f7bd9f7a8f70da551ae61dad 335 Gene3D G3DSA:3.40.50.620 12 211 9.3E-77 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS03810 71ce2740f7bd9f7a8f70da551ae61dad 335 Pfam PF00579 tRNA synthetases class I (W and Y) 10 279 2.4E-66 T 11-11-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS03810 71ce2740f7bd9f7a8f70da551ae61dad 335 Gene3D G3DSA:1.10.240.10 212 328 9.7E-15 T 11-11-2016 TW_RS03810 71ce2740f7bd9f7a8f70da551ae61dad 335 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 10 333 3.2E-95 T 11-11-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TW_RS03810 71ce2740f7bd9f7a8f70da551ae61dad 335 SUPERFAMILY SSF52374 13 333 1.08E-86 T 11-11-2016 TW_RS03810 71ce2740f7bd9f7a8f70da551ae61dad 335 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 11 335 35.492 T 11-11-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 TW_RS00670 bb3fce535125e33e5799c241c8c085e0 93 Gene3D G3DSA:4.10.520.10 5 93 3.7E-25 T 11-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 TW_RS00670 bb3fce535125e33e5799c241c8c085e0 93 SMART SM00411 4 93 1.1E-23 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TW_RS00670 bb3fce535125e33e5799c241c8c085e0 93 SUPERFAMILY SSF47729 4 93 4.71E-24 T 11-11-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 TW_RS00670 bb3fce535125e33e5799c241c8c085e0 93 Pfam PF00216 Bacterial DNA-binding protein 4 93 5.4E-25 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TW_RS00670 bb3fce535125e33e5799c241c8c085e0 93 PRINTS PR01727 Prokaryotic integration host factor signature 43 58 1.8E-5 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TW_RS00670 bb3fce535125e33e5799c241c8c085e0 93 PRINTS PR01727 Prokaryotic integration host factor signature 61 74 1.8E-5 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TW_RS00670 bb3fce535125e33e5799c241c8c085e0 93 PRINTS PR01727 Prokaryotic integration host factor signature 77 91 1.8E-5 T 11-11-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 TW_RS02180 60ec41681d8885db215ddc795cb424c4 410 Pfam PF02441 Flavoprotein 8 130 1.1E-27 T 11-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TW_RS02180 60ec41681d8885db215ddc795cb424c4 410 Gene3D G3DSA:3.40.50.10300 182 397 4.3E-67 T 11-11-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TW_RS02180 60ec41681d8885db215ddc795cb424c4 410 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 8 394 4.7E-105 T 11-11-2016 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5 TW_RS02180 60ec41681d8885db215ddc795cb424c4 410 Gene3D G3DSA:3.40.50.1950 8 179 1.4E-50 T 11-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TW_RS02180 60ec41681d8885db215ddc795cb424c4 410 SUPERFAMILY SSF102645 183 397 3.53E-60 T 11-11-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TW_RS02180 60ec41681d8885db215ddc795cb424c4 410 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 184 370 2.2E-58 T 11-11-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TW_RS02180 60ec41681d8885db215ddc795cb424c4 410 SUPERFAMILY SSF52507 8 175 1.2E-51 T 11-11-2016 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TW_RS02250 a70762eb7e8686740af5ed451fde9667 422 SUPERFAMILY SSF53448 5 238 1.92E-38 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS02250 a70762eb7e8686740af5ed451fde9667 422 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 302 317 - T 11-11-2016 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TW_RS02250 a70762eb7e8686740af5ed451fde9667 422 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 239 4.0E-41 T 11-11-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TW_RS02250 a70762eb7e8686740af5ed451fde9667 422 Hamap MF_01520 Bifunctional enzyme IspD/IspF [ispDF]. 1 422 32.231 T 11-11-2016 IPR026596 Bifunctional enzyme IspD/IspF KEGG: 00900+4.6.1.12+2.7.7.60|MetaCyc: PWY-7560 TW_RS02250 a70762eb7e8686740af5ed451fde9667 422 Pfam PF02542 YgbB family 269 419 4.4E-37 T 11-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TW_RS02250 a70762eb7e8686740af5ed451fde9667 422 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 267 421 23.882 T 11-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TW_RS02250 a70762eb7e8686740af5ed451fde9667 422 Gene3D G3DSA:3.30.1330.50 267 420 1.5E-40 T 11-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TW_RS02250 a70762eb7e8686740af5ed451fde9667 422 SUPERFAMILY SSF69765 268 420 7.59E-41 T 11-11-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TW_RS02250 a70762eb7e8686740af5ed451fde9667 422 Gene3D G3DSA:3.90.550.10 3 239 7.9E-48 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS03780 518976cf6a901f6124ad13daafd5d968 162 Gene3D G3DSA:3.10.50.30 81 159 6.8E-12 T 11-11-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TW_RS03780 518976cf6a901f6124ad13daafd5d968 162 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 157 9.9E-11 T 11-11-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TW_RS03780 518976cf6a901f6124ad13daafd5d968 162 SUPERFAMILY SSF54534 84 157 1.57E-8 T 11-11-2016 TW_RS03780 518976cf6a901f6124ad13daafd5d968 162 PIRSF PIRSF006092 1 160 1.5E-27 T 11-11-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TW_RS03780 518976cf6a901f6124ad13daafd5d968 162 SUPERFAMILY SSF46557 7 79 9.02E-21 T 11-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TW_RS03780 518976cf6a901f6124ad13daafd5d968 162 Gene3D G3DSA:1.10.287.180 6 77 4.7E-25 T 11-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TW_RS03780 518976cf6a901f6124ad13daafd5d968 162 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 11-11-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TW_RS03780 518976cf6a901f6124ad13daafd5d968 162 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 2.3E-24 T 11-11-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TW_RS00930 fd17bb11faef874254af5a18b020166b 583 Gene3D G3DSA:3.40.50.300 337 562 5.5E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00930 fd17bb11faef874254af5a18b020166b 583 Gene3D G3DSA:1.20.1560.10 21 316 5.4E-40 T 11-11-2016 TW_RS00930 fd17bb11faef874254af5a18b020166b 583 Pfam PF00005 ABC transporter 353 502 5.7E-25 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS00930 fd17bb11faef874254af5a18b020166b 583 SUPERFAMILY SSF52540 327 573 6.09E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00930 fd17bb11faef874254af5a18b020166b 583 SMART SM00382 361 548 2.3E-13 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00930 fd17bb11faef874254af5a18b020166b 583 Pfam PF00664 ABC transporter transmembrane region 35 289 2.5E-22 T 11-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TW_RS00930 fd17bb11faef874254af5a18b020166b 583 SUPERFAMILY SSF90123 16 300 1.96E-42 T 11-11-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 TW_RS00930 fd17bb11faef874254af5a18b020166b 583 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS01180 6007bb4666a42972c09abbca10289caa 80 Pfam PF00831 Ribosomal L29 protein 12 67 2.6E-22 T 11-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01180 6007bb4666a42972c09abbca10289caa 80 TIGRFAM TIGR00012 L29: ribosomal protein uL29 12 67 1.2E-18 T 11-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01180 6007bb4666a42972c09abbca10289caa 80 SUPERFAMILY SSF46561 10 70 5.36E-19 T 11-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01180 6007bb4666a42972c09abbca10289caa 80 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 8 67 16.191 T 11-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01180 6007bb4666a42972c09abbca10289caa 80 Gene3D G3DSA:1.10.287.310 10 71 3.9E-26 T 11-11-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS00385 b96d71bbc7d52858ce4514b6903b5921 527 Gene3D G3DSA:3.40.50.970 349 514 2.4E-15 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS00385 b96d71bbc7d52858ce4514b6903b5921 527 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 527 25.386 T 11-11-2016 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 TW_RS00385 b96d71bbc7d52858ce4514b6903b5921 527 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 8 418 1.7E-103 T 11-11-2016 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 TW_RS00385 b96d71bbc7d52858ce4514b6903b5921 527 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 175 1.9E-26 T 11-11-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TW_RS00385 b96d71bbc7d52858ce4514b6903b5921 527 PIRSF PIRSF004983 1 526 9.8E-143 T 11-11-2016 IPR004433 Menaquinone biosynthesis protein MenD GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 TW_RS00385 b96d71bbc7d52858ce4514b6903b5921 527 SUPERFAMILY SSF52518 357 515 9.38E-18 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS00385 b96d71bbc7d52858ce4514b6903b5921 527 SUPERFAMILY SSF52518 11 182 5.4E-27 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS00385 b96d71bbc7d52858ce4514b6903b5921 527 Gene3D G3DSA:3.40.50.970 9 177 1.0E-39 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS03245 db326fb1b4cb5913945fa9d1d32c3387 220 SUPERFAMILY SSF52540 7 199 1.78E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03245 db326fb1b4cb5913945fa9d1d32c3387 220 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS03245 db326fb1b4cb5913945fa9d1d32c3387 220 Pfam PF00005 ABC transporter 27 167 1.9E-27 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS03245 db326fb1b4cb5913945fa9d1d32c3387 220 Gene3D G3DSA:3.40.50.300 6 217 1.1E-48 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03245 db326fb1b4cb5913945fa9d1d32c3387 220 SMART SM00382 36 220 2.9E-5 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS03690 ee2e4876d6e5a1800299a2f1ee04c9fa 299 Gene3D G3DSA:3.90.79.10 12 172 2.9E-24 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TW_RS03690 ee2e4876d6e5a1800299a2f1ee04c9fa 299 Gene3D G3DSA:3.40.50.1240 180 286 1.7E-13 T 11-11-2016 IPR029033 Histidine phosphatase superfamily TW_RS03690 ee2e4876d6e5a1800299a2f1ee04c9fa 299 Pfam PF00293 NUDIX domain 29 159 3.9E-11 T 11-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TW_RS03690 ee2e4876d6e5a1800299a2f1ee04c9fa 299 SUPERFAMILY SSF55811 14 170 1.22E-22 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TW_RS03690 ee2e4876d6e5a1800299a2f1ee04c9fa 299 SMART SM00855 180 278 0.0042 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 TW_RS03690 ee2e4876d6e5a1800299a2f1ee04c9fa 299 SUPERFAMILY SSF53254 179 282 3.33E-15 T 11-11-2016 IPR029033 Histidine phosphatase superfamily TW_RS03690 ee2e4876d6e5a1800299a2f1ee04c9fa 299 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 182 246 1.7E-6 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 TW_RS03690 ee2e4876d6e5a1800299a2f1ee04c9fa 299 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 11-11-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TW_RS02490 3ff26946f5e32d71d35c4c321f77d433 81 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 6.5E-8 T 11-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TW_RS02490 3ff26946f5e32d71d35c4c321f77d433 81 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 6.5E-8 T 11-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TW_RS02490 3ff26946f5e32d71d35c4c321f77d433 81 PRINTS PR01651 Protein-export SecG membrane protein signature 57 79 6.5E-8 T 11-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TW_RS02490 3ff26946f5e32d71d35c4c321f77d433 81 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 6 76 3.6E-18 T 11-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TW_RS02490 3ff26946f5e32d71d35c4c321f77d433 81 Pfam PF03840 Preprotein translocase SecG subunit 7 75 2.1E-15 T 11-11-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 Gene3D G3DSA:3.40.50.620 6 238 2.3E-90 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 Gene3D G3DSA:1.10.240.10 239 331 1.8E-33 T 11-11-2016 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 Pfam PF00579 tRNA synthetases class I (W and Y) 36 326 6.2E-74 T 11-11-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 46 56 - T 11-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 50 72 4.1E-23 T 11-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 168 183 4.1E-23 T 11-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 189 211 4.1E-23 T 11-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 222 234 4.1E-23 T 11-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 SUPERFAMILY SSF52374 8 327 5.06E-91 T 11-11-2016 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 8 471 41.444 T 11-11-2016 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 Pfam PF01479 S4 domain 408 438 1.3E-7 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 SUPERFAMILY SSF55174 405 469 2.75E-11 T 11-11-2016 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 Gene3D G3DSA:3.10.290.10 392 471 1.3E-31 T 11-11-2016 IPR002942 RNA-binding S4 domain GO:0003723 TW_RS03295 f154ce5a438e6fd3ebaa295b03073115 471 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 10 468 5.1E-101 T 11-11-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TW_RS01570 ddf43d345c1d31a9ac8a39075e1c1c75 104 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 16.546 T 11-11-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01570 ddf43d345c1d31a9ac8a39075e1c1c75 104 SUPERFAMILY SSF141091 2 100 6.54E-22 T 11-11-2016 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01570 ddf43d345c1d31a9ac8a39075e1c1c75 104 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 4.7E-12 T 11-11-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01570 ddf43d345c1d31a9ac8a39075e1c1c75 104 Pfam PF00829 Ribosomal prokaryotic L21 protein 2 100 8.0E-22 T 11-11-2016 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03820 2a3ae8e7c0c6cb4c0eac6279dd4c75c7 237 SUPERFAMILY SSF63380 34 109 1.19E-17 T 11-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TW_RS03820 2a3ae8e7c0c6cb4c0eac6279dd4c75c7 237 SUPERFAMILY SSF63380 115 231 1.74E-26 T 11-11-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 TW_RS03820 2a3ae8e7c0c6cb4c0eac6279dd4c75c7 237 PIRSF PIRSF000498 29 236 3.9E-53 T 11-11-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS03820 2a3ae8e7c0c6cb4c0eac6279dd4c75c7 237 Pfam PF00677 Lumazine binding domain 121 220 7.4E-22 T 11-11-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS03820 2a3ae8e7c0c6cb4c0eac6279dd4c75c7 237 Pfam PF00677 Lumazine binding domain 4 107 2.9E-13 T 11-11-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS03820 2a3ae8e7c0c6cb4c0eac6279dd4c75c7 237 Gene3D G3DSA:2.40.30.20 34 123 3.4E-23 T 11-11-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 TW_RS03820 2a3ae8e7c0c6cb4c0eac6279dd4c75c7 237 Gene3D G3DSA:2.40.30.20 124 221 2.9E-24 T 11-11-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 TW_RS02805 19b239611e29672cf5cec479e7c8c86f 122 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 104 121 - T 11-11-2016 IPR017870 FeS cluster insertion, C-terminal, conserved site TW_RS02805 19b239611e29672cf5cec479e7c8c86f 122 SUPERFAMILY SSF89360 18 112 7.06E-29 T 11-11-2016 IPR000361 FeS cluster biogenesis TW_RS02805 19b239611e29672cf5cec479e7c8c86f 122 Pfam PF01521 Iron-sulphur cluster biosynthesis 18 119 6.3E-18 T 11-11-2016 IPR000361 FeS cluster biogenesis TW_RS02805 19b239611e29672cf5cec479e7c8c86f 122 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 18 122 9.9E-36 T 11-11-2016 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 TW_RS02805 19b239611e29672cf5cec479e7c8c86f 122 Gene3D G3DSA:2.60.300.12 18 112 1.9E-29 T 11-11-2016 IPR000361 FeS cluster biogenesis TW_RS02295 8798b3a1eac1c94063dcadefea435d3d 370 PIRSF PIRSF036915 5 370 4.9E-150 T 11-11-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TW_RS02295 8798b3a1eac1c94063dcadefea435d3d 370 ProSitePatterns PS01054 Transaldolase signature 1. 47 55 - T 11-11-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 TW_RS02295 8798b3a1eac1c94063dcadefea435d3d 370 Hamap MF_00493 Transaldolase [tal]. 1 370 134.144 T 11-11-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TW_RS02295 8798b3a1eac1c94063dcadefea435d3d 370 TIGRFAM TIGR00876 tal_mycobact: transaldolase 17 364 1.3E-117 T 11-11-2016 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TW_RS02295 8798b3a1eac1c94063dcadefea435d3d 370 Pfam PF00923 Transaldolase 21 364 1.8E-73 T 11-11-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336 TW_RS02295 8798b3a1eac1c94063dcadefea435d3d 370 SUPERFAMILY SSF51569 10 369 4.03E-72 T 11-11-2016 TW_RS02295 8798b3a1eac1c94063dcadefea435d3d 370 Gene3D G3DSA:3.20.20.70 9 366 7.6E-110 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 Gene3D G3DSA:3.50.30.20 1 130 2.0E-46 T 11-11-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 1 124 9.2E-42 T 11-11-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 363 38.994 T 11-11-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 1 360 1.3E-118 T 11-11-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 SUPERFAMILY SSF52021 1 131 2.22E-45 T 11-11-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 PRINTS PR00096 Glutamine amidotransferase superfamily signature 213 222 2.5E-10 T 11-11-2016 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 PRINTS PR00096 Glutamine amidotransferase superfamily signature 334 347 2.5E-10 T 11-11-2016 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 252 2.5E-10 T 11-11-2016 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 SMART SM01097 1 125 1.3E-66 T 11-11-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 Gene3D G3DSA:3.40.50.880 134 361 3.2E-55 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 275 1.4E-29 T 11-11-2016 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 171 185 1.4E-29 T 11-11-2016 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 283 294 1.4E-29 T 11-11-2016 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 257 1.4E-29 T 11-11-2016 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 210 224 1.4E-29 T 11-11-2016 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 PRINTS PR00097 Anthranilate synthase component II signature 213 222 2.1E-5 T 11-11-2016 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 PRINTS PR00097 Anthranilate synthase component II signature 334 347 2.1E-5 T 11-11-2016 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 PRINTS PR00097 Anthranilate synthase component II signature 241 252 2.1E-5 T 11-11-2016 TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 Pfam PF00117 Glutamine amidotransferase class-I 173 357 5.9E-34 T 11-11-2016 IPR017926 Glutamine amidotransferase TW_RS02155 5a666e028bfd5b08b0d37ce26a6708d8 371 SUPERFAMILY SSF52317 147 362 9.6E-47 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS01765 6b8b220f2db0396901864fee699995e4 335 SUPERFAMILY SSF54211 10 158 2.66E-27 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS01765 6b8b220f2db0396901864fee699995e4 335 PIRSF PIRSF000676 7 326 7.8E-86 T 11-11-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TW_RS01765 6b8b220f2db0396901864fee699995e4 335 Gene3D G3DSA:3.30.230.10 10 158 6.0E-44 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TW_RS01765 6b8b220f2db0396901864fee699995e4 335 Pfam PF00288 GHMP kinases N terminal domain 87 150 1.6E-9 T 11-11-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 TW_RS01765 6b8b220f2db0396901864fee699995e4 335 Pfam PF08544 GHMP kinases C terminal 250 304 1.9E-5 T 11-11-2016 IPR013750 GHMP kinase, C-terminal domain TW_RS01765 6b8b220f2db0396901864fee699995e4 335 Gene3D G3DSA:3.30.70.890 189 303 4.5E-30 T 11-11-2016 IPR013750 GHMP kinase, C-terminal domain TW_RS01765 6b8b220f2db0396901864fee699995e4 335 PRINTS PR00958 Homoserine kinase signature 196 213 1.3E-28 T 11-11-2016 TW_RS01765 6b8b220f2db0396901864fee699995e4 335 PRINTS PR00958 Homoserine kinase signature 273 288 1.3E-28 T 11-11-2016 TW_RS01765 6b8b220f2db0396901864fee699995e4 335 PRINTS PR00958 Homoserine kinase signature 137 150 1.3E-28 T 11-11-2016 TW_RS01765 6b8b220f2db0396901864fee699995e4 335 PRINTS PR00958 Homoserine kinase signature 100 115 1.3E-28 T 11-11-2016 TW_RS01765 6b8b220f2db0396901864fee699995e4 335 PRINTS PR00958 Homoserine kinase signature 18 33 1.3E-28 T 11-11-2016 TW_RS01765 6b8b220f2db0396901864fee699995e4 335 SUPERFAMILY SSF55060 191 292 3.6E-23 T 11-11-2016 IPR013750 GHMP kinase, C-terminal domain TW_RS01765 6b8b220f2db0396901864fee699995e4 335 TIGRFAM TIGR00191 thrB: homoserine kinase 11 324 4.8E-60 T 11-11-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TW_RS01765 6b8b220f2db0396901864fee699995e4 335 Hamap MF_00384 Homoserine kinase [thrB]. 11 324 26.328 T 11-11-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TW_RS02330 3e2321aeed5901611e7035aa5ce0fb72 249 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 245 3.0E-98 T 11-11-2016 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 TW_RS02330 3e2321aeed5901611e7035aa5ce0fb72 249 SUPERFAMILY SSF52540 3 232 6.93E-39 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02330 3e2321aeed5901611e7035aa5ce0fb72 249 Gene3D G3DSA:3.40.50.300 3 232 2.6E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02330 3e2321aeed5901611e7035aa5ce0fb72 249 Pfam PF00005 ABC transporter 23 174 7.9E-21 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS00135 dcd9f40745d0c1c208e4834be961df13 248 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 6 241 1.8E-40 T 11-11-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS00135 dcd9f40745d0c1c208e4834be961df13 248 Gene3D G3DSA:2.30.30.100 198 239 6.7E-6 T 11-11-2016 TW_RS00135 dcd9f40745d0c1c208e4834be961df13 248 Gene3D G3DSA:3.30.930.10 3 174 4.5E-44 T 11-11-2016 TW_RS00135 dcd9f40745d0c1c208e4834be961df13 248 SUPERFAMILY SSF55681 3 173 6.71E-40 T 11-11-2016 TW_RS00135 dcd9f40745d0c1c208e4834be961df13 248 Pfam PF03099 Biotin/lipoate A/B protein ligase family 11 133 7.2E-15 T 11-11-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 TW_RS00135 dcd9f40745d0c1c208e4834be961df13 248 Pfam PF02237 Biotin protein ligase C terminal domain 197 241 4.1E-7 T 11-11-2016 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TW_RS03905 a5ce8d564fe5a551c840043f7e129f88 294 Gene3D G3DSA:3.60.21.10 46 234 3.7E-15 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like TW_RS03905 a5ce8d564fe5a551c840043f7e129f88 294 SUPERFAMILY SSF56300 43 284 3.17E-24 T 11-11-2016 IPR029052 Metallo-dependent phosphatase-like TW_RS03905 a5ce8d564fe5a551c840043f7e129f88 294 Pfam PF00149 Calcineurin-like phosphoesterase 47 230 5.5E-8 T 11-11-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 TW_RS02760 8ba28546a43d6a9d61d2e05f4b424e38 411 Gene3D G3DSA:3.40.47.10 7 258 4.6E-54 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TW_RS02760 8ba28546a43d6a9d61d2e05f4b424e38 411 Gene3D G3DSA:3.40.47.10 262 408 7.6E-51 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TW_RS02760 8ba28546a43d6a9d61d2e05f4b424e38 411 SUPERFAMILY SSF53901 3 250 4.21E-56 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TW_RS02760 8ba28546a43d6a9d61d2e05f4b424e38 411 SMART SM00825 Beta-ketoacyl synthase 5 401 1.1E-12 T 11-11-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TW_RS02760 8ba28546a43d6a9d61d2e05f4b424e38 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 245 6.2E-43 T 11-11-2016 IPR014030 Beta-ketoacyl synthase, N-terminal TW_RS02760 8ba28546a43d6a9d61d2e05f4b424e38 411 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 253 367 7.4E-32 T 11-11-2016 IPR014031 Beta-ketoacyl synthase, C-terminal TW_RS02760 8ba28546a43d6a9d61d2e05f4b424e38 411 SUPERFAMILY SSF53901 213 408 9.6E-60 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TW_RS01190 3d7bd6839c8616229a83e87fc42cefb4 123 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 123 2.4E-53 T 11-11-2016 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 TW_RS01190 3d7bd6839c8616229a83e87fc42cefb4 123 Gene3D G3DSA:2.40.150.20 2 123 1.1E-49 T 11-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TW_RS01190 3d7bd6839c8616229a83e87fc42cefb4 123 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 123 26.437 T 11-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TW_RS01190 3d7bd6839c8616229a83e87fc42cefb4 123 SMART SM01374 1 123 2.3E-79 T 11-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TW_RS01190 3d7bd6839c8616229a83e87fc42cefb4 123 ProSitePatterns PS00049 Ribosomal protein L14 signature. 61 87 - T 11-11-2016 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01190 3d7bd6839c8616229a83e87fc42cefb4 123 Pfam PF00238 Ribosomal protein L14p/L23e 2 123 1.2E-50 T 11-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TW_RS01190 3d7bd6839c8616229a83e87fc42cefb4 123 SUPERFAMILY SSF50193 2 123 2.09E-46 T 11-11-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 Gene3D G3DSA:3.30.310.50 453 538 1.7E-10 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 Gene3D G3DSA:3.40.120.10 227 306 5.7E-20 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 SUPERFAMILY SSF53738 301 434 1.12E-29 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 Gene3D G3DSA:3.40.120.10 307 433 2.5E-35 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 SUPERFAMILY SSF55957 435 533 2.62E-7 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 207 313 5.6E-26 T 11-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 141 155 9.4E-7 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 245 9.4E-7 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 293 308 9.4E-7 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 SUPERFAMILY SSF53738 223 314 2.03E-17 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 47 185 1.6E-32 T 11-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 318 426 9.1E-16 T 11-11-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 Gene3D G3DSA:3.40.120.10 27 211 1.7E-48 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 142 151 - T 11-11-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00095 15545a5e8ccf666a50232f379dd0d836 550 SUPERFAMILY SSF53738 35 232 7.95E-38 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 Gene3D G3DSA:3.40.50.300 590 667 3.8E-58 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 Gene3D G3DSA:3.40.50.300 8 59 6.5E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 Gene3D G3DSA:3.40.50.300 833 950 3.8E-58 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 Gene3D G3DSA:3.40.50.300 470 584 6.5E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 Gene3D G3DSA:1.20.1580.10 255 289 3.0E-49 T 11-11-2016 TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 Gene3D G3DSA:1.20.1580.10 99 137 3.0E-49 T 11-11-2016 TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 Gene3D G3DSA:1.20.1580.10 398 469 3.0E-49 T 11-11-2016 TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 Pfam PF00005 ABC transporter 611 872 1.2E-9 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 SUPERFAMILY SSF52540 602 649 9.82E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 SUPERFAMILY SSF52540 696 926 9.82E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 Gene3D G3DSA:3.30.1490.20 208 247 3.8E-18 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 Gene3D G3DSA:3.30.1490.20 138 161 3.8E-18 T 11-11-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 Gene3D G3DSA:1.10.8.280 291 386 1.3E-10 T 11-11-2016 TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 Gene3D G3DSA:1.20.1580.10 706 832 1.4E-51 T 11-11-2016 TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 12 661 7.4E-243 T 11-11-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 ProSitePatterns PS00211 ABC transporters family signature. 842 856 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 SUPERFAMILY SSF52540 13 212 1.41E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 SUPERFAMILY SSF52540 422 561 1.41E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02525 66900546d9a8094c039fe9c151567ff8 952 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS01325 c1b9cad959b353055d7d5e294754fef7 585 Pfam PF13361 UvrD-like helicase C-terminal domain 510 567 7.8E-19 T 11-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TW_RS01325 c1b9cad959b353055d7d5e294754fef7 585 Pfam PF00580 UvrD/REP helicase N-terminal domain 127 269 6.0E-24 T 11-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TW_RS01325 c1b9cad959b353055d7d5e294754fef7 585 Pfam PF00580 UvrD/REP helicase N-terminal domain 9 82 1.2E-14 T 11-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TW_RS01325 c1b9cad959b353055d7d5e294754fef7 585 Gene3D G3DSA:3.40.50.300 279 317 8.4E-33 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01325 c1b9cad959b353055d7d5e294754fef7 585 Gene3D G3DSA:3.40.50.300 360 431 8.4E-33 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01325 c1b9cad959b353055d7d5e294754fef7 585 Gene3D G3DSA:3.40.50.300 508 576 8.4E-33 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01325 c1b9cad959b353055d7d5e294754fef7 585 Gene3D G3DSA:3.40.50.300 8 272 1.6E-55 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01325 c1b9cad959b353055d7d5e294754fef7 585 SUPERFAMILY SSF52540 352 576 7.79E-96 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01325 c1b9cad959b353055d7d5e294754fef7 585 SUPERFAMILY SSF52540 6 304 7.79E-96 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03850 623356dc5715cc0aff71f9353f90773c 512 Gene3D G3DSA:3.40.50.1820 332 333 4.7E-40 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold TW_RS03850 623356dc5715cc0aff71f9353f90773c 512 Gene3D G3DSA:3.40.50.1820 193 298 4.7E-40 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold TW_RS03850 623356dc5715cc0aff71f9353f90773c 512 Gene3D G3DSA:3.40.50.1820 64 147 4.7E-40 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold TW_RS03850 623356dc5715cc0aff71f9353f90773c 512 Gene3D G3DSA:3.40.50.1820 377 495 4.7E-40 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold TW_RS03850 623356dc5715cc0aff71f9353f90773c 512 Pfam PF00561 alpha/beta hydrolase fold 99 282 7.2E-18 T 11-11-2016 IPR000073 Alpha/beta hydrolase fold-1 TW_RS03850 623356dc5715cc0aff71f9353f90773c 512 SUPERFAMILY SSF53474 93 145 2.41E-24 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold TW_RS03850 623356dc5715cc0aff71f9353f90773c 512 SUPERFAMILY SSF53474 190 474 2.41E-24 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold TW_RS03850 623356dc5715cc0aff71f9353f90773c 512 Pfam PF08386 TAP-like protein 405 506 7.6E-28 T 11-11-2016 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal TW_RS04275 c538fff38fcb07d2287b48f4ed7e98f1 585 Gene3D G3DSA:3.30.200.20 5 80 2.0E-20 T 11-11-2016 TW_RS04275 c538fff38fcb07d2287b48f4ed7e98f1 585 SUPERFAMILY SSF56112 10 267 9.98E-76 T 11-11-2016 IPR011009 Protein kinase-like domain TW_RS04275 c538fff38fcb07d2287b48f4ed7e98f1 585 SMART SM00220 13 270 6.5E-60 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TW_RS04275 c538fff38fcb07d2287b48f4ed7e98f1 585 Gene3D G3DSA:1.10.510.10 81 264 8.8E-51 T 11-11-2016 TW_RS04275 c538fff38fcb07d2287b48f4ed7e98f1 585 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 11-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TW_RS04275 c538fff38fcb07d2287b48f4ed7e98f1 585 Pfam PF00069 Protein kinase domain 14 257 5.1E-48 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TW_RS03475 ca81af233e39c97d77383feff3794513 193 Gene3D G3DSA:3.90.950.10 1 186 1.2E-59 T 11-11-2016 IPR029001 Inosine triphosphate pyrophosphatase-like TW_RS03475 ca81af233e39c97d77383feff3794513 193 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 1 186 43.927 T 11-11-2016 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 TW_RS03475 ca81af233e39c97d77383feff3794513 193 SUPERFAMILY SSF52972 1 185 3.14E-55 T 11-11-2016 IPR029001 Inosine triphosphate pyrophosphatase-like TW_RS03475 ca81af233e39c97d77383feff3794513 193 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 2 184 1.8E-46 T 11-11-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 TW_RS03475 ca81af233e39c97d77383feff3794513 193 Pfam PF01725 Ham1 family 3 180 2.4E-47 T 11-11-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206|Reactome: R-HSA-15869 TW_RS03205 c45ab39f77e0e483b1a155ebfbae8efc 374 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 11 351 1.5E-126 T 11-11-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TW_RS03205 c45ab39f77e0e483b1a155ebfbae8efc 374 PIRSF PIRSF004640 4 363 7.5E-142 T 11-11-2016 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TW_RS03205 c45ab39f77e0e483b1a155ebfbae8efc 374 SUPERFAMILY SSF56014 268 351 1.98E-12 T 11-11-2016 TW_RS03205 c45ab39f77e0e483b1a155ebfbae8efc 374 Pfam PF04551 GcpE protein 14 354 1.3E-129 T 11-11-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TW_RS03205 c45ab39f77e0e483b1a155ebfbae8efc 374 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 9 360 33.337 T 11-11-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TW_RS03205 c45ab39f77e0e483b1a155ebfbae8efc 374 Gene3D G3DSA:3.20.20.70 28 129 1.8E-6 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS03205 c45ab39f77e0e483b1a155ebfbae8efc 374 SUPERFAMILY SSF51717 19 212 3.61E-9 T 11-11-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TW_RS01275 9463c37217f44c6c8c06b870b9ec3b0d 267 Gene3D G3DSA:3.30.70.580 3 109 8.7E-28 T 11-11-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 TW_RS01275 9463c37217f44c6c8c06b870b9ec3b0d 267 Gene3D G3DSA:3.30.70.660 111 247 1.6E-28 T 11-11-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 TW_RS01275 9463c37217f44c6c8c06b870b9ec3b0d 267 SUPERFAMILY SSF55120 2 255 3.6E-66 T 11-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TW_RS01275 9463c37217f44c6c8c06b870b9ec3b0d 267 Pfam PF01416 tRNA pseudouridine synthase 148 250 7.3E-17 T 11-11-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TW_RS01275 9463c37217f44c6c8c06b870b9ec3b0d 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 4 249 28.923 T 11-11-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TW_RS01275 9463c37217f44c6c8c06b870b9ec3b0d 267 PIRSF PIRSF001430 3 266 1.6E-78 T 11-11-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TW_RS01010 d55a93d788df26771572f5e60e04c318 230 Gene3D G3DSA:3.40.470.10 9 229 2.4E-76 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TW_RS01010 d55a93d788df26771572f5e60e04c318 230 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 64 73 - T 11-11-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TW_RS01010 d55a93d788df26771572f5e60e04c318 230 SUPERFAMILY SSF52141 12 229 1.59E-69 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TW_RS01010 d55a93d788df26771572f5e60e04c318 230 SMART SM00987 56 217 2.0E-27 T 11-11-2016 TW_RS01010 d55a93d788df26771572f5e60e04c318 230 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 14 228 32.23 T 11-11-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TW_RS01010 d55a93d788df26771572f5e60e04c318 230 Pfam PF03167 Uracil DNA glycosylase superfamily 58 220 1.6E-16 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TW_RS01010 d55a93d788df26771572f5e60e04c318 230 SMART SM00986 56 217 2.0E-27 T 11-11-2016 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TW_RS01010 d55a93d788df26771572f5e60e04c318 230 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 16 219 4.2E-57 T 11-11-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TW_RS04260 69205aeb564e47cbc1d7daa840ce5b66 149 SUPERFAMILY SSF49879 45 147 5.74E-27 T 11-11-2016 IPR008984 SMAD/FHA domain GO:0005515 TW_RS04260 69205aeb564e47cbc1d7daa840ce5b66 149 Pfam PF00498 FHA domain 77 142 4.1E-19 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TW_RS04260 69205aeb564e47cbc1d7daa840ce5b66 149 SMART SM00240 75 125 1.2E-14 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TW_RS04260 69205aeb564e47cbc1d7daa840ce5b66 149 Gene3D G3DSA:2.60.200.20 58 147 4.0E-25 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TW_RS01270 9afcc15866338522adb8b96415d5b983 179 Pfam PF01196 Ribosomal protein L17 21 116 6.6E-30 T 11-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01270 9afcc15866338522adb8b96415d5b983 179 TIGRFAM TIGR00059 L17: ribosomal protein bL17 15 116 9.3E-32 T 11-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01270 9afcc15866338522adb8b96415d5b983 179 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 11-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01270 9afcc15866338522adb8b96415d5b983 179 Gene3D G3DSA:3.90.1030.10 8 116 4.6E-37 T 11-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01270 9afcc15866338522adb8b96415d5b983 179 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 22.96 T 11-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01270 9afcc15866338522adb8b96415d5b983 179 SUPERFAMILY SSF64263 5 116 2.09E-38 T 11-11-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00050 c2843ccf7e11c6936f7fa92ec2bac2ee 230 Gene3D G3DSA:2.60.120.320 124 202 1.9E-6 T 11-11-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TW_RS00050 c2843ccf7e11c6936f7fa92ec2bac2ee 230 SMART SM00983 125 200 1.9E-14 T 11-11-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TW_RS00050 c2843ccf7e11c6936f7fa92ec2bac2ee 230 SUPERFAMILY SSF63999 6 125 5.1E-26 T 11-11-2016 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TW_RS00050 c2843ccf7e11c6936f7fa92ec2bac2ee 230 SUPERFAMILY SSF63862 140 202 1.57E-6 T 11-11-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TW_RS00050 c2843ccf7e11c6936f7fa92ec2bac2ee 230 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 25 122 2.0E-15 T 11-11-2016 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TW_RS00050 c2843ccf7e11c6936f7fa92ec2bac2ee 230 Gene3D G3DSA:3.40.50.10240 25 123 1.8E-18 T 11-11-2016 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TW_RS00050 c2843ccf7e11c6936f7fa92ec2bac2ee 230 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 7 202 8.4E-56 T 11-11-2016 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TW_RS00050 c2843ccf7e11c6936f7fa92ec2bac2ee 230 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 144 199 7.6E-7 T 11-11-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TW_RS00450 e817b5e2e36af698454a8f9485c6c1c2 743 Pfam PF13361 UvrD-like helicase C-terminal domain 293 626 1.3E-71 T 11-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TW_RS00450 e817b5e2e36af698454a8f9485c6c1c2 743 Gene3D G3DSA:3.40.50.300 562 652 1.8E-68 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00450 e817b5e2e36af698454a8f9485c6c1c2 743 Gene3D G3DSA:3.40.50.300 296 403 1.8E-68 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00450 e817b5e2e36af698454a8f9485c6c1c2 743 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 287 2.9E-69 T 11-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TW_RS00450 e817b5e2e36af698454a8f9485c6c1c2 743 SUPERFAMILY SSF52540 4 650 1.04E-157 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00450 e817b5e2e36af698454a8f9485c6c1c2 743 Gene3D G3DSA:3.40.50.300 9 291 1.5E-76 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00450 e817b5e2e36af698454a8f9485c6c1c2 743 Gene3D G3DSA:1.10.486.10 404 547 6.5E-38 T 11-11-2016 TW_RS03255 7422b5e76b5e410921b5b61d0e8c2948 390 Pfam PF02687 FtsX-like permease family 263 380 2.9E-11 T 11-11-2016 IPR003838 ABC transporter permease protein domain GO:0016020 TW_RS04175 147c3f421371ad74b10daa2dfce66923 228 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 21 208 7.9E-31 T 11-11-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 TW_RS01755 40218ce7e7234862573ff2f1b7965137 489 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 214 236 - T 11-11-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TW_RS01755 40218ce7e7234862573ff2f1b7965137 489 Pfam PF00742 Homoserine dehydrogenase 168 348 1.2E-61 T 11-11-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TW_RS01755 40218ce7e7234862573ff2f1b7965137 489 SUPERFAMILY SSF55347 168 335 1.05E-48 T 11-11-2016 TW_RS01755 40218ce7e7234862573ff2f1b7965137 489 SUPERFAMILY SSF51735 36 189 1.04E-26 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS01755 40218ce7e7234862573ff2f1b7965137 489 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 44 160 1.4E-15 T 11-11-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TW_RS01755 40218ce7e7234862573ff2f1b7965137 489 Gene3D G3DSA:3.40.50.720 36 179 7.9E-40 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS01755 40218ce7e7234862573ff2f1b7965137 489 Gene3D G3DSA:3.30.360.10 180 331 2.0E-51 T 11-11-2016 TW_RS00660 45d53e62353d49a492d00d387a833eb2 56 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 56 2.5E-21 T 11-11-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00660 45d53e62353d49a492d00d387a833eb2 56 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 2 56 14.339 T 11-11-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00660 45d53e62353d49a492d00d387a833eb2 56 SUPERFAMILY SSF57829 5 56 2.87E-17 T 11-11-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 TW_RS00660 45d53e62353d49a492d00d387a833eb2 56 Pfam PF00471 Ribosomal protein L33 11 56 2.8E-16 T 11-11-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00660 45d53e62353d49a492d00d387a833eb2 56 ProSitePatterns PS00582 Ribosomal protein L33 signature. 24 43 - T 11-11-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03890 0050fed3fb228d51ed3e67772a793422 314 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 5 295 6.1E-113 T 11-11-2016 IPR022399 Helicase/secretion neighbourhood ATPase TW_RS03890 0050fed3fb228d51ed3e67772a793422 314 Pfam PF00437 Type II/IV secretion system protein 9 284 1.4E-64 T 11-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 TW_RS03890 0050fed3fb228d51ed3e67772a793422 314 Gene3D G3DSA:3.30.450.90 7 100 1.4E-21 T 11-11-2016 TW_RS03890 0050fed3fb228d51ed3e67772a793422 314 Gene3D G3DSA:3.40.50.300 105 292 1.3E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03890 0050fed3fb228d51ed3e67772a793422 314 SUPERFAMILY SSF52540 5 282 6.06E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03415 abf2528d98086acf722e7007a04b0eef 459 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 1 423 7.5E-127 T 11-11-2016 TW_RS03415 abf2528d98086acf722e7007a04b0eef 459 Pfam PF00919 Uncharacterized protein family UPF0004 1 89 4.7E-21 T 11-11-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 TW_RS03415 abf2528d98086acf722e7007a04b0eef 459 Gene3D G3DSA:3.80.30.20 131 362 8.8E-80 T 11-11-2016 IPR023404 Radical SAM, alpha/beta horseshoe TW_RS03415 abf2528d98086acf722e7007a04b0eef 459 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 428 61.564 T 11-11-2016 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 TW_RS03415 abf2528d98086acf722e7007a04b0eef 459 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 136 156 - T 11-11-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 TW_RS03415 abf2528d98086acf722e7007a04b0eef 459 SMART SM00729 132 350 4.8E-54 T 11-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TW_RS03415 abf2528d98086acf722e7007a04b0eef 459 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 1 424 1.1E-140 T 11-11-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 TW_RS03415 abf2528d98086acf722e7007a04b0eef 459 Pfam PF04055 Radical SAM superfamily 136 308 6.2E-27 T 11-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TW_RS03415 abf2528d98086acf722e7007a04b0eef 459 SUPERFAMILY SSF102114 117 355 6.15E-57 T 11-11-2016 TW_RS00100 4207ba17b876219886193ea24392c4bf 277 Gene3D G3DSA:3.40.50.1580 12 268 1.5E-77 T 11-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TW_RS00100 4207ba17b876219886193ea24392c4bf 277 PIRSF PIRSF000477 4 269 1.2E-74 T 11-11-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 TW_RS00100 4207ba17b876219886193ea24392c4bf 277 SUPERFAMILY SSF53167 14 268 3.06E-72 T 11-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TW_RS00100 4207ba17b876219886193ea24392c4bf 277 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 29 266 6.3E-64 T 11-11-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217|Reactome: R-HSA-74259 TW_RS00100 4207ba17b876219886193ea24392c4bf 277 Pfam PF01048 Phosphorylase superfamily 29 267 6.7E-39 T 11-11-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TW_RS00625 94c6da75f1afc63f71708e18147c9b5a 100 Gene3D G3DSA:3.30.70.60 7 98 9.6E-17 T 11-11-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TW_RS00625 94c6da75f1afc63f71708e18147c9b5a 100 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 6 99 13.082 T 11-11-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 TW_RS00625 94c6da75f1afc63f71708e18147c9b5a 100 SUPERFAMILY SSF54995 6 98 9.55E-17 T 11-11-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00625 94c6da75f1afc63f71708e18147c9b5a 100 Pfam PF01250 Ribosomal protein S6 9 95 7.1E-13 T 11-11-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 SMART SM00388 249 316 4.9E-16 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 SUPERFAMILY SSF47384 233 314 1.24E-16 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 SUPERFAMILY SSF55874 306 470 1.83E-38 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 468 5.1E-23 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 Gene3D G3DSA:3.30.565.10 302 472 2.4E-43 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 SUPERFAMILY SSF158472 191 238 3.53E-5 T 11-11-2016 TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 Pfam PF00672 HAMP domain 169 237 3.4E-9 T 11-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 Pfam PF00512 His Kinase A (phospho-acceptor) domain 250 315 3.4E-14 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 Gene3D G3DSA:1.10.287.130 247 301 2.9E-16 T 11-11-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 SMART SM00387 358 470 1.9E-33 T 11-11-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 423 3.4E-14 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 448 3.4E-14 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 454 467 3.4E-14 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 409 3.4E-14 T 11-11-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TW_RS00250 9ff7ea5b7614352884aef7cd542e79fb 484 SMART SM00304 188 241 1.1E-5 T 11-11-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 TW_RS02895 57ed04fad831d77b9bdd421e26e9878f 369 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 9.5E-6 T 11-11-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TW_RS02895 57ed04fad831d77b9bdd421e26e9878f 369 Pfam PF00953 Glycosyl transferase family 4 82 289 7.2E-32 T 11-11-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TW_RS02895 57ed04fad831d77b9bdd421e26e9878f 369 ProSitePatterns PS01348 MraY family signature 2. 187 198 - T 11-11-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TW_RS02895 57ed04fad831d77b9bdd421e26e9878f 369 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 358 2.0E-82 T 11-11-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TW_RS02895 57ed04fad831d77b9bdd421e26e9878f 369 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 11-11-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TW_RS02895 57ed04fad831d77b9bdd421e26e9878f 369 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 363 22.231 T 11-11-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TW_RS02510 ef70433fe0a5aaa3598c4c35258f109f 202 SUPERFAMILY SSF54719 84 195 8.51E-38 T 11-11-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TW_RS02510 ef70433fe0a5aaa3598c4c35258f109f 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 191 4.0E-32 T 11-11-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TW_RS02510 ef70433fe0a5aaa3598c4c35258f109f 202 PRINTS PR01703 Manganese superoxide dismutase signature 157 169 7.8E-22 T 11-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TW_RS02510 ef70433fe0a5aaa3598c4c35258f109f 202 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 7.8E-22 T 11-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TW_RS02510 ef70433fe0a5aaa3598c4c35258f109f 202 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 7.8E-22 T 11-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TW_RS02510 ef70433fe0a5aaa3598c4c35258f109f 202 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 7.8E-22 T 11-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TW_RS02510 ef70433fe0a5aaa3598c4c35258f109f 202 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 7.8E-22 T 11-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TW_RS02510 ef70433fe0a5aaa3598c4c35258f109f 202 PIRSF PIRSF000349 1 200 3.1E-71 T 11-11-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TW_RS02510 ef70433fe0a5aaa3598c4c35258f109f 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 4 83 5.7E-31 T 11-11-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TW_RS02510 ef70433fe0a5aaa3598c4c35258f109f 202 SUPERFAMILY SSF46609 3 85 3.67E-33 T 11-11-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TW_RS02510 ef70433fe0a5aaa3598c4c35258f109f 202 Gene3D G3DSA:1.10.287.990 21 84 8.9E-25 T 11-11-2016 TW_RS02510 ef70433fe0a5aaa3598c4c35258f109f 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 159 166 - T 11-11-2016 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 TW_RS00995 488a7782ced25e9b7b37c96c7e3a4c66 149 Pfam PF11377 Protein of unknown function (DUF3180) 9 139 5.5E-19 T 11-11-2016 IPR021517 Protein of unknown function DUF3180 TW_RS03835 f53945219fcb8036e153e4152774487a 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 24 155 7.7E-38 T 11-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS03835 f53945219fcb8036e153e4152774487a 156 Gene3D G3DSA:3.40.50.960 14 156 8.6E-39 T 11-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS03835 f53945219fcb8036e153e4152774487a 156 SUPERFAMILY SSF52121 16 156 1.44E-38 T 11-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS03835 f53945219fcb8036e153e4152774487a 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 24 154 8.1E-27 T 11-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS03835 f53945219fcb8036e153e4152774487a 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 19 156 21.316 T 11-11-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS03630 2f5fb696dc8905bbbc5103d965829e1c 223 SUPERFAMILY SSF53639 3 209 2.75E-65 T 11-11-2016 IPR001303 Class II aldolase/adducin N-terminal TW_RS03630 2f5fb696dc8905bbbc5103d965829e1c 223 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 182 5.5E-49 T 11-11-2016 IPR001303 Class II aldolase/adducin N-terminal TW_RS03630 2f5fb696dc8905bbbc5103d965829e1c 223 SMART SM01007 7 184 1.2E-68 T 11-11-2016 IPR001303 Class II aldolase/adducin N-terminal TW_RS03630 2f5fb696dc8905bbbc5103d965829e1c 223 Gene3D G3DSA:3.40.225.10 2 212 2.2E-72 T 11-11-2016 IPR001303 Class II aldolase/adducin N-terminal TW_RS01675 9d6095afe19c840dd5cfa93ab4fd94aa 495 SUPERFAMILY SSF54211 2 147 3.79E-32 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS01675 9d6095afe19c840dd5cfa93ab4fd94aa 495 Gene3D G3DSA:3.30.230.10 1 147 4.2E-32 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TW_RS01675 9d6095afe19c840dd5cfa93ab4fd94aa 495 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 394 488 1.1E-16 T 11-11-2016 IPR025158 Mg chelatase-related protein, C-terminal domain TW_RS01675 9d6095afe19c840dd5cfa93ab4fd94aa 495 SMART SM00382 197 380 4.9E-10 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS01675 9d6095afe19c840dd5cfa93ab4fd94aa 495 Pfam PF13541 Subunit ChlI of Mg-chelatase 5 126 2.4E-38 T 11-11-2016 TW_RS01675 9d6095afe19c840dd5cfa93ab4fd94aa 495 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 2 488 2.5E-129 T 11-11-2016 IPR004482 Mg chelatase-related protein TW_RS01675 9d6095afe19c840dd5cfa93ab4fd94aa 495 Gene3D G3DSA:3.40.50.300 177 374 2.3E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01675 9d6095afe19c840dd5cfa93ab4fd94aa 495 SUPERFAMILY SSF52540 177 410 1.5E-36 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01675 9d6095afe19c840dd5cfa93ab4fd94aa 495 SUPERFAMILY SSF52540 451 485 1.5E-36 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01675 9d6095afe19c840dd5cfa93ab4fd94aa 495 Pfam PF01078 Magnesium chelatase, subunit ChlI 177 383 6.9E-84 T 11-11-2016 IPR000523 Magnesium chelatase ChlI domain TW_RS03950 a93d9f95a37f4429798affd83e74f9bc 141 Gene3D G3DSA:1.10.10.250 73 140 1.7E-25 T 11-11-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TW_RS03950 a93d9f95a37f4429798affd83e74f9bc 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 10 67 1.2E-28 T 11-11-2016 IPR020784 Ribosomal protein L11, N-terminal TW_RS03950 a93d9f95a37f4429798affd83e74f9bc 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 6 141 29.013 T 11-11-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TW_RS03950 a93d9f95a37f4429798affd83e74f9bc 141 SUPERFAMILY SSF54747 4 73 1.83E-29 T 11-11-2016 IPR020784 Ribosomal protein L11, N-terminal TW_RS03950 a93d9f95a37f4429798affd83e74f9bc 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 37 74 2.0E-16 T 11-11-2016 TW_RS03950 a93d9f95a37f4429798affd83e74f9bc 141 SUPERFAMILY SSF46906 68 140 8.24E-23 T 11-11-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TW_RS03950 a93d9f95a37f4429798affd83e74f9bc 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 4 140 1.6E-58 T 11-11-2016 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS03950 a93d9f95a37f4429798affd83e74f9bc 141 SMART SM00649 10 141 1.6E-72 T 11-11-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TW_RS03950 a93d9f95a37f4429798affd83e74f9bc 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 1.7E-19 T 11-11-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TW_RS03950 a93d9f95a37f4429798affd83e74f9bc 141 Gene3D G3DSA:3.30.1550.10 4 72 5.0E-38 T 11-11-2016 IPR020784 Ribosomal protein L11, N-terminal TW_RS02315 adc006f6399d51ef9f3066b520dd3b01 473 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 17 464 1.2E-216 T 11-11-2016 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 TW_RS02315 adc006f6399d51ef9f3066b520dd3b01 473 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 7.5E-72 T 11-11-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TW_RS02315 adc006f6399d51ef9f3066b520dd3b01 473 SUPERFAMILY SSF101960 39 470 5.23E-136 T 11-11-2016 TW_RS03370 3033ca1173560053a085a6419f0099d2 404 Gene3D G3DSA:3.20.20.105 21 403 4.1E-141 T 11-11-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TW_RS03370 3033ca1173560053a085a6419f0099d2 404 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 22 401 8.5E-127 T 11-11-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TW_RS03370 3033ca1173560053a085a6419f0099d2 404 Pfam PF01702 Queuine tRNA-ribosyltransferase 168 396 6.1E-76 T 11-11-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TW_RS03370 3033ca1173560053a085a6419f0099d2 404 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 20 396 45.482 T 11-11-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TW_RS03370 3033ca1173560053a085a6419f0099d2 404 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 22 402 3.3E-125 T 11-11-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TW_RS03370 3033ca1173560053a085a6419f0099d2 404 SUPERFAMILY SSF51713 20 402 1.44E-129 T 11-11-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TW_RS03970 a29b13ed8c5d5cce5f4199c6e4a06d2d 404 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 11-11-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TW_RS03970 a29b13ed8c5d5cce5f4199c6e4a06d2d 404 Pfam PF00155 Aminotransferase class I and II 34 381 2.6E-67 T 11-11-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TW_RS03970 a29b13ed8c5d5cce5f4199c6e4a06d2d 404 Gene3D G3DSA:3.90.1150.10 275 395 1.2E-36 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TW_RS03970 a29b13ed8c5d5cce5f4199c6e4a06d2d 404 Gene3D G3DSA:3.40.640.10 46 274 2.1E-72 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TW_RS03970 a29b13ed8c5d5cce5f4199c6e4a06d2d 404 SUPERFAMILY SSF53383 5 394 7.18E-106 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase TW_RS00575 114b71b4c892424e258eaf10490c03e7 545 Gene3D G3DSA:3.40.50.300 4 283 1.2E-125 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00575 114b71b4c892424e258eaf10490c03e7 545 SUPERFAMILY SSF52317 288 532 8.06E-70 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS00575 114b71b4c892424e258eaf10490c03e7 545 Pfam PF00117 Glutamine amidotransferase class-I 300 526 3.9E-49 T 11-11-2016 IPR017926 Glutamine amidotransferase TW_RS00575 114b71b4c892424e258eaf10490c03e7 545 SUPERFAMILY SSF52540 4 267 5.67E-113 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00575 114b71b4c892424e258eaf10490c03e7 545 Gene3D G3DSA:3.40.50.880 287 532 2.9E-86 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS00575 114b71b4c892424e258eaf10490c03e7 545 Pfam PF06418 CTP synthase N-terminus 5 265 1.1E-116 T 11-11-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TW_RS00575 114b71b4c892424e258eaf10490c03e7 545 TIGRFAM TIGR00337 PyrG: CTP synthase 4 527 2.3E-219 T 11-11-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TW_RS00575 114b71b4c892424e258eaf10490c03e7 545 Hamap MF_01227 CTP synthase [pyrG]. 4 532 46.996 T 11-11-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TW_RS01830 1db97335dae3087cae6f06d42f128950 474 Gene3D G3DSA:2.40.10.170 4 81 9.7E-29 T 11-11-2016 TW_RS01830 1db97335dae3087cae6f06d42f128950 474 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 342 351 - T 11-11-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01830 1db97335dae3087cae6f06d42f128950 474 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 80 5.3E-21 T 11-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01830 1db97335dae3087cae6f06d42f128950 474 Gene3D G3DSA:1.10.1140.10 354 472 3.4E-45 T 11-11-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01830 1db97335dae3087cae6f06d42f128950 474 Hamap MF_01347 ATP synthase subunit beta [atpB]. 4 469 54.988 T 11-11-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 TW_RS01830 1db97335dae3087cae6f06d42f128950 474 SUPERFAMILY SSF47917 354 470 1.12E-45 T 11-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01830 1db97335dae3087cae6f06d42f128950 474 SMART SM00382 150 413 8.8E-6 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS01830 1db97335dae3087cae6f06d42f128950 474 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 138 351 5.3E-64 T 11-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01830 1db97335dae3087cae6f06d42f128950 474 SUPERFAMILY SSF50615 6 81 3.66E-25 T 11-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01830 1db97335dae3087cae6f06d42f128950 474 SUPERFAMILY SSF52540 84 356 8.36E-88 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01830 1db97335dae3087cae6f06d42f128950 474 Gene3D G3DSA:3.40.50.300 84 353 1.4E-102 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01830 1db97335dae3087cae6f06d42f128950 474 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 6 468 5.5E-235 T 11-11-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201 TW_RS01105 adfdb719a3be7e42d40a9bec9b4bd230 401 Gene3D G3DSA:3.40.50.2300 327 377 1.8E-29 T 11-11-2016 TW_RS01105 adfdb719a3be7e42d40a9bec9b4bd230 401 Gene3D G3DSA:3.40.50.2300 63 185 1.8E-29 T 11-11-2016 TW_RS01105 adfdb719a3be7e42d40a9bec9b4bd230 401 SUPERFAMILY SSF53822 65 397 5.38E-62 T 11-11-2016 IPR028082 Periplasmic binding protein-like I TW_RS01105 adfdb719a3be7e42d40a9bec9b4bd230 401 Pfam PF13458 Periplasmic binding protein 65 390 3.8E-40 T 11-11-2016 IPR028081 Leucine-binding protein domain TW_RS01105 adfdb719a3be7e42d40a9bec9b4bd230 401 Gene3D G3DSA:3.40.50.2300 191 326 3.8E-28 T 11-11-2016 TW_RS01105 adfdb719a3be7e42d40a9bec9b4bd230 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 64 80 8.0E-5 T 11-11-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TW_RS01105 adfdb719a3be7e42d40a9bec9b4bd230 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 285 303 8.0E-5 T 11-11-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 Gene3D G3DSA:3.40.50.800 495 586 5.0E-15 T 11-11-2016 IPR004154 Anticodon-binding TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 SUPERFAMILY SSF55826 307 404 6.45E-5 T 11-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 Gene3D G3DSA:3.90.960.10 317 396 6.7E-6 T 11-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 Gene3D G3DSA:3.30.930.10 415 494 1.0E-82 T 11-11-2016 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 Gene3D G3DSA:3.30.930.10 13 237 1.0E-82 T 11-11-2016 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 Pfam PF03129 Anticodon binding domain 508 582 1.2E-10 T 11-11-2016 IPR004154 Anticodon-binding TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 483 2.1E-39 T 11-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 586 33.259 T 11-11-2016 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 SUPERFAMILY SSF52954 488 584 1.54E-19 T 11-11-2016 IPR004154 Anticodon-binding TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 2.0E-15 T 11-11-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 2.0E-15 T 11-11-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 2.0E-15 T 11-11-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 2.0E-15 T 11-11-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 Pfam PF04073 Aminoacyl-tRNA editing domain 282 405 5.1E-7 T 11-11-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 5 576 2.8E-137 T 11-11-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 SUPERFAMILY SSF55681 431 502 1.91E-86 T 11-11-2016 TW_RS03215 0dcae44d6320476f842b4bbbb2daa107 601 SUPERFAMILY SSF55681 12 240 1.91E-86 T 11-11-2016 TW_RS01255 94400140f3175f45047d5712a7b54ab8 124 Gene3D G3DSA:1.10.8.50 2 72 3.4E-28 T 11-11-2016 TW_RS01255 94400140f3175f45047d5712a7b54ab8 124 PIRSF PIRSF002134 1 124 2.2E-41 T 11-11-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01255 94400140f3175f45047d5712a7b54ab8 124 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 26.697 T 11-11-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01255 94400140f3175f45047d5712a7b54ab8 124 Gene3D G3DSA:4.10.910.10 73 122 3.2E-24 T 11-11-2016 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01255 94400140f3175f45047d5712a7b54ab8 124 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 11-11-2016 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01255 94400140f3175f45047d5712a7b54ab8 124 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.6E-49 T 11-11-2016 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01255 94400140f3175f45047d5712a7b54ab8 124 SUPERFAMILY SSF46946 2 121 7.21E-44 T 11-11-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TW_RS01255 94400140f3175f45047d5712a7b54ab8 124 Pfam PF00416 Ribosomal protein S13/S18 3 108 4.2E-30 T 11-11-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS04375 50ea529bbf283103e83720738c07a526 75 Gene3D G3DSA:3.30.1280.10 1 67 3.2E-20 T 11-11-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TW_RS04375 50ea529bbf283103e83720738c07a526 75 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 3 62 1.0E-28 T 11-11-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TW_RS04375 50ea529bbf283103e83720738c07a526 75 SUPERFAMILY SSF82697 2 66 8.02E-17 T 11-11-2016 TW_RS04375 50ea529bbf283103e83720738c07a526 75 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 1 67 1.1E-16 T 11-11-2016 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TW_RS01090 451fef9390346fe76ac0753a3e605b3c 249 Pfam PF04203 Sortase family 100 232 3.3E-23 T 11-11-2016 IPR005754 Sortase family TW_RS01090 451fef9390346fe76ac0753a3e605b3c 249 SUPERFAMILY SSF63817 91 235 1.1E-25 T 11-11-2016 IPR023365 Sortase domain TW_RS01090 451fef9390346fe76ac0753a3e605b3c 249 Gene3D G3DSA:2.40.260.10 92 236 5.8E-22 T 11-11-2016 IPR023365 Sortase domain TW_RS00395 e51d19013969969465bc249a87710211 303 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 23 278 6.7E-46 T 11-11-2016 TW_RS00395 e51d19013969969465bc249a87710211 303 Pfam PF01040 UbiA prenyltransferase family 37 274 2.9E-29 T 11-11-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 TW_RS00395 e51d19013969969465bc249a87710211 303 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 14 301 18.021 T 11-11-2016 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TW_RS00395 e51d19013969969465bc249a87710211 303 PIRSF PIRSF005355 6 303 1.3E-84 T 11-11-2016 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 TW_RS01065 4223d03c9d256422fc82fdc60079febc 180 Gene3D G3DSA:1.10.10.10 41 81 2.2E-4 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 SUPERFAMILY SSF50993 2 281 6.54E-51 T 11-11-2016 TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 SUPERFAMILY SSF50993 324 378 6.54E-51 T 11-11-2016 TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 Gene3D G3DSA:2.130.10.120 1 273 1.9E-96 T 11-11-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 Gene3D G3DSA:2.130.10.120 315 380 1.9E-96 T 11-11-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 Pfam PF00326 Prolyl oligopeptidase family 434 648 4.4E-62 T 11-11-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 SUPERFAMILY SSF53474 390 630 3.11E-43 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 2 375 3.1E-58 T 11-11-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 473 492 4.9E-49 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 419 437 4.9E-49 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 582 604 4.9E-49 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 445 469 4.9E-49 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 503 523 4.9E-49 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 562 577 4.9E-49 T 11-11-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TW_RS01450 0c2396c5d54630deb475bc0ac15dc490 651 Gene3D G3DSA:3.40.50.1820 387 628 2.0E-35 T 11-11-2016 IPR029058 Alpha/Beta hydrolase fold TW_RS02950 577a315aa6882062fb1808c602d44940 221 SUPERFAMILY SSF69593 2 214 9.29E-46 T 11-11-2016 TW_RS02950 577a315aa6882062fb1808c602d44940 221 Pfam PF01553 Acyltransferase 25 148 1.3E-24 T 11-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TW_RS02950 577a315aa6882062fb1808c602d44940 221 SMART SM00563 33 152 1.3E-30 T 11-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TW_RS02950 577a315aa6882062fb1808c602d44940 221 Gene3D G3DSA:3.40.1130.10 25 205 8.0E-28 T 11-11-2016 TW_RS00195 2228b89277e2003bb56ab0d28f15d1e0 323 Gene3D G3DSA:3.90.550.10 3 231 2.4E-45 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS00195 2228b89277e2003bb56ab0d28f15d1e0 323 Pfam PF00535 Glycosyl transferase family 2 4 134 1.6E-24 T 11-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TW_RS00195 2228b89277e2003bb56ab0d28f15d1e0 323 SUPERFAMILY SSF53448 3 226 4.5E-45 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS02935 a989b48a49794c223dd6407643dc857e 379 Gene3D G3DSA:1.10.600.10 24 375 4.4E-67 T 11-11-2016 IPR008949 Isoprenoid synthase domain TW_RS02935 a989b48a49794c223dd6407643dc857e 379 Pfam PF00348 Polyprenyl synthetase 55 331 9.2E-44 T 11-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 TW_RS02935 a989b48a49794c223dd6407643dc857e 379 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 104 118 - T 11-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 TW_RS02935 a989b48a49794c223dd6407643dc857e 379 SUPERFAMILY SSF48576 20 375 2.16E-60 T 11-11-2016 IPR008949 Isoprenoid synthase domain TW_RS03020 b4675eaf81c889f16838e57e7d8d7cc0 214 Pfam PF05345 Putative Ig domain 9 50 1.2E-11 T 11-11-2016 IPR008009 Putative Ig TW_RS02425 47efb37943307e9be39518f12f443627 450 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 186 204 9.4E-18 T 11-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TW_RS02425 47efb37943307e9be39518f12f443627 450 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 219 240 9.4E-18 T 11-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TW_RS02425 47efb37943307e9be39518f12f443627 450 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 60 69 9.4E-18 T 11-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TW_RS02425 47efb37943307e9be39518f12f443627 450 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 24 35 9.4E-18 T 11-11-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TW_RS02425 47efb37943307e9be39518f12f443627 450 SUPERFAMILY SSF52374 24 320 5.35E-49 T 11-11-2016 TW_RS02425 47efb37943307e9be39518f12f443627 450 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 322 2.8E-61 T 11-11-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TW_RS02425 47efb37943307e9be39518f12f443627 450 Gene3D G3DSA:3.40.50.620 23 314 1.4E-50 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS00185 033624a282ecfc1e1bc89cbc60d26dee 268 SMART SM00382 77 248 3.3E-8 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00185 033624a282ecfc1e1bc89cbc60d26dee 268 Pfam PF00005 ABC transporter 68 199 1.6E-18 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS00185 033624a282ecfc1e1bc89cbc60d26dee 268 Gene3D G3DSA:3.40.50.300 26 257 3.1E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00185 033624a282ecfc1e1bc89cbc60d26dee 268 SUPERFAMILY SSF52540 53 256 1.17E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01590 dbef71f0033e33bc0c3db281a654a569 201 Gene3D G3DSA:3.40.50.620 12 198 7.1E-66 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS01590 dbef71f0033e33bc0c3db281a654a569 201 SUPERFAMILY SSF52374 12 198 2.66E-53 T 11-11-2016 TW_RS01590 dbef71f0033e33bc0c3db281a654a569 201 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 15 196 8.0E-52 T 11-11-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 TW_RS01590 dbef71f0033e33bc0c3db281a654a569 201 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 11 197 30.582 T 11-11-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: R-HSA-196807 TW_RS01590 dbef71f0033e33bc0c3db281a654a569 201 Pfam PF01467 Cytidylyltransferase-like 15 171 1.8E-26 T 11-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TW_RS01590 dbef71f0033e33bc0c3db281a654a569 201 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 13 72 3.2E-9 T 11-11-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TW_RS01240 b3bc5b5679291ae69c6890b050fd2551 186 Pfam PF00406 Adenylate kinase 5 159 4.3E-36 T 11-11-2016 TW_RS01240 b3bc5b5679291ae69c6890b050fd2551 186 PRINTS PR00094 Adenylate kinase signature 32 46 4.0E-25 T 11-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TW_RS01240 b3bc5b5679291ae69c6890b050fd2551 186 PRINTS PR00094 Adenylate kinase signature 146 160 4.0E-25 T 11-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TW_RS01240 b3bc5b5679291ae69c6890b050fd2551 186 PRINTS PR00094 Adenylate kinase signature 129 144 4.0E-25 T 11-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TW_RS01240 b3bc5b5679291ae69c6890b050fd2551 186 PRINTS PR00094 Adenylate kinase signature 4 17 4.0E-25 T 11-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TW_RS01240 b3bc5b5679291ae69c6890b050fd2551 186 PRINTS PR00094 Adenylate kinase signature 77 93 4.0E-25 T 11-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TW_RS01240 b3bc5b5679291ae69c6890b050fd2551 186 SUPERFAMILY SSF52540 2 182 1.98E-33 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01240 b3bc5b5679291ae69c6890b050fd2551 186 Gene3D G3DSA:3.40.50.300 2 182 3.0E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01240 b3bc5b5679291ae69c6890b050fd2551 186 ProSitePatterns PS00113 Adenylate kinase signature. 77 88 - T 11-11-2016 TW_RS01240 b3bc5b5679291ae69c6890b050fd2551 186 Hamap MF_00235 Adenylate kinase [adk]. 1 182 34.435 T 11-11-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TW_RS01100 9b043ea40627713467e5e1f92d89056c 223 SMART SM00535 19 152 2.8E-50 T 11-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 TW_RS01100 9b043ea40627713467e5e1f92d89056c 223 Gene3D G3DSA:3.30.160.20 157 219 1.6E-17 T 11-11-2016 IPR014720 Double-stranded RNA-binding domain TW_RS01100 9b043ea40627713467e5e1f92d89056c 223 Pfam PF00035 Double-stranded RNA binding motif 158 218 1.7E-11 T 11-11-2016 IPR014720 Double-stranded RNA-binding domain TW_RS01100 9b043ea40627713467e5e1f92d89056c 223 Gene3D G3DSA:1.10.1520.10 18 148 3.5E-41 T 11-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 TW_RS01100 9b043ea40627713467e5e1f92d89056c 223 ProSitePatterns PS00517 Ribonuclease III family signature. 41 49 - T 11-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 TW_RS01100 9b043ea40627713467e5e1f92d89056c 223 SMART SM00358 158 219 4.5E-16 T 11-11-2016 IPR014720 Double-stranded RNA-binding domain TW_RS01100 9b043ea40627713467e5e1f92d89056c 223 SUPERFAMILY SSF69065 14 150 2.62E-43 T 11-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 TW_RS01100 9b043ea40627713467e5e1f92d89056c 223 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 19 217 3.9E-62 T 11-11-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 TW_RS01100 9b043ea40627713467e5e1f92d89056c 223 Pfam PF14622 Ribonuclease-III-like 19 141 1.5E-35 T 11-11-2016 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 TW_RS01100 9b043ea40627713467e5e1f92d89056c 223 SUPERFAMILY SSF54768 113 218 1.07E-19 T 11-11-2016 TW_RS01100 9b043ea40627713467e5e1f92d89056c 223 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 215 27.044 T 11-11-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 SUPERFAMILY SSF54991 865 960 7.45E-20 T 11-11-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Gene3D G3DSA:3.30.930.10 675 856 2.9E-60 T 11-11-2016 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Gene3D G3DSA:3.30.930.10 579 619 2.9E-60 T 11-11-2016 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 SUPERFAMILY SSF56037 265 447 1.2E-60 T 11-11-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 SMART SM00896 869 960 7.7E-27 T 11-11-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Pfam PF01588 Putative tRNA binding domain 128 191 4.8E-5 T 11-11-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Pfam PF03484 tRNA synthetase B5 domain 461 533 5.8E-12 T 11-11-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Pfam PF03147 Ferredoxin-fold anticodon binding domain 870 960 2.0E-18 T 11-11-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 SUPERFAMILY SSF46955 461 537 1.01E-12 T 11-11-2016 IPR009061 Putative DNA-binding domain TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 4 954 39.625 T 11-11-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Pfam PF03483 B3/4 domain 273 441 6.7E-57 T 11-11-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 SUPERFAMILY SSF50249 123 250 4.0E-17 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Gene3D G3DSA:3.30.56.20 457 537 3.7E-16 T 11-11-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Gene3D G3DSA:3.30.70.380 872 960 2.1E-19 T 11-11-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Gene3D G3DSA:3.50.40.10 272 447 1.7E-64 T 11-11-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Reactome: R-HSA-379716 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 SMART SM00873 270 442 3.2E-68 T 11-11-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 SUPERFAMILY SSF55681 756 857 2.24E-29 T 11-11-2016 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 SUPERFAMILY SSF55681 673 724 2.24E-29 T 11-11-2016 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Gene3D G3DSA:2.40.50.140 64 214 9.3E-31 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS03300 ef59779baf44cb02a75f81db52542439 961 SMART SM00874 458 533 3.9E-15 T 11-11-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Gene3D G3DSA:3.30.56.10 6 61 5.0E-6 T 11-11-2016 TW_RS03300 ef59779baf44cb02a75f81db52542439 961 Gene3D G3DSA:3.30.56.10 217 245 5.0E-6 T 11-11-2016 TW_RS01670 3aa36389bbacb3a247415985de26ad98 120 Pfam PF02021 Uncharacterised protein family UPF0102 14 105 2.6E-19 T 11-11-2016 IPR003509 Uncharacterised protein family UPF0102 TW_RS01670 3aa36389bbacb3a247415985de26ad98 120 Gene3D G3DSA:3.40.1350.10 14 119 2.1E-24 T 11-11-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 Reactome: R-HSA-6784531 TW_RS01670 3aa36389bbacb3a247415985de26ad98 120 Hamap MF_00048 UPF0102 protein YraN [yraN]. 7 118 16.825 T 11-11-2016 IPR003509 Uncharacterised protein family UPF0102 TW_RS01670 3aa36389bbacb3a247415985de26ad98 120 SUPERFAMILY SSF52980 13 106 2.15E-21 T 11-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 Gene3D G3DSA:3.90.930.12 83 177 3.5E-35 T 11-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 Gene3D G3DSA:3.90.930.12 2 82 1.4E-26 T 11-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 6.0E-29 T 11-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 6.0E-29 T 11-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 6.0E-29 T 11-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 Pfam PF00347 Ribosomal protein L6 11 82 1.0E-14 T 11-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 Pfam PF00347 Ribosomal protein L6 90 164 8.2E-16 T 11-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.464 T 11-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 SUPERFAMILY SSF56053 1 82 3.12E-22 T 11-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 SUPERFAMILY SSF56053 83 176 9.78E-33 T 11-11-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 2.7E-67 T 11-11-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 11-11-2016 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01210 d110056d4a15e0ca6ab1270606f22236 178 PIRSF PIRSF002162 1 177 1.1E-42 T 11-11-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS02175 5e2f767f7f58b5b6463c0cfa37548f07 85 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 7 77 1.1E-16 T 11-11-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS02175 5e2f767f7f58b5b6463c0cfa37548f07 85 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 7 80 14.961 T 11-11-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TW_RS02175 5e2f767f7f58b5b6463c0cfa37548f07 85 SUPERFAMILY SSF63562 7 81 3.14E-20 T 11-11-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 TW_RS02175 5e2f767f7f58b5b6463c0cfa37548f07 85 Pfam PF01192 RNA polymerase Rpb6 15 78 2.4E-12 T 11-11-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 TW_RS02175 5e2f767f7f58b5b6463c0cfa37548f07 85 SMART SM01409 14 79 3.0E-12 T 11-11-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 TW_RS02175 5e2f767f7f58b5b6463c0cfa37548f07 85 Gene3D G3DSA:3.90.940.10 7 81 1.2E-22 T 11-11-2016 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 TW_RS02625 fce22e1480a5f2b1d8b11de49f8f9735 224 Pfam PF09348 Domain of unknown function (DUF1990) 40 99 4.5E-6 T 11-11-2016 IPR018960 Domain of unknown function DUF1990 TW_RS02625 fce22e1480a5f2b1d8b11de49f8f9735 224 Pfam PF09348 Domain of unknown function (DUF1990) 130 200 1.8E-4 T 11-11-2016 IPR018960 Domain of unknown function DUF1990 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 437 473 2.8E-8 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 SUPERFAMILY SSF53738 280 381 1.2E-21 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 Gene3D G3DSA:3.30.310.50 388 473 5.2E-13 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 170 267 1.6E-21 T 11-11-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 21 128 3.6E-29 T 11-11-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 Gene3D G3DSA:3.40.120.10 266 387 2.8E-25 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 SUPERFAMILY SSF53738 21 128 2.0E-30 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 184 203 1.9E-20 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 220 233 1.9E-20 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 249 264 1.9E-20 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 105 119 1.9E-20 T 11-11-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 Gene3D G3DSA:3.40.120.10 21 128 7.3E-26 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 Gene3D G3DSA:3.40.120.10 186 265 1.8E-28 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 275 382 1.4E-17 T 11-11-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 SUPERFAMILY SSF53738 169 270 5.1E-25 T 11-11-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00720 06c9c91ac134d4e7be175f84aad3c7c0 476 SUPERFAMILY SSF55957 386 473 2.62E-13 T 11-11-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TW_RS00365 1d68f23646cac744b4c3493fae6177f6 498 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 17 497 1.3E-97 T 11-11-2016 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 TW_RS00365 1d68f23646cac744b4c3493fae6177f6 498 SMART SM00155 214 241 0.036 T 11-11-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TW_RS00365 1d68f23646cac744b4c3493fae6177f6 498 SMART SM00155 411 438 0.0036 T 11-11-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TW_RS00365 1d68f23646cac744b4c3493fae6177f6 498 Gene3D G3DSA:3.30.870.10 105 328 8.5E-39 T 11-11-2016 TW_RS00365 1d68f23646cac744b4c3493fae6177f6 498 Gene3D G3DSA:3.30.870.10 329 475 2.1E-33 T 11-11-2016 TW_RS00365 1d68f23646cac744b4c3493fae6177f6 498 SUPERFAMILY SSF56024 313 481 1.1E-40 T 11-11-2016 TW_RS00365 1d68f23646cac744b4c3493fae6177f6 498 Pfam PF13396 Phospholipase_D-nuclease N-terminal 20 57 1.2E-5 T 11-11-2016 IPR027379 Cardiolipin synthase N-terminal TW_RS00365 1d68f23646cac744b4c3493fae6177f6 498 Pfam PF13091 PLD-like domain 129 237 2.7E-13 T 11-11-2016 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 TW_RS00365 1d68f23646cac744b4c3493fae6177f6 498 Pfam PF13091 PLD-like domain 341 460 3.5E-24 T 11-11-2016 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148 TW_RS00365 1d68f23646cac744b4c3493fae6177f6 498 SUPERFAMILY SSF56024 76 326 8.3E-46 T 11-11-2016 TW_RS04345 55ee20274c6e9b62981f0689b075d5bb 370 SUPERFAMILY SSF52518 29 362 2.46E-81 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS04345 55ee20274c6e9b62981f0689b075d5bb 370 Gene3D G3DSA:3.40.50.970 3 361 4.1E-103 T 11-11-2016 IPR029061 Thiamin diphosphate-binding fold TW_RS04345 55ee20274c6e9b62981f0689b075d5bb 370 Pfam PF00676 Dehydrogenase E1 component 47 310 2.1E-62 T 11-11-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 TW_RS04345 55ee20274c6e9b62981f0689b075d5bb 370 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 8 362 3.3E-125 T 11-11-2016 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TW_RS03080 000004b119bf49e30e98721797a8702f 379 Gene3D G3DSA:1.20.1250.20 3 172 1.3E-20 T 11-11-2016 TW_RS03080 000004b119bf49e30e98721797a8702f 379 Gene3D G3DSA:1.20.1250.20 192 368 1.2E-16 T 11-11-2016 TW_RS03080 000004b119bf49e30e98721797a8702f 379 SUPERFAMILY SSF103473 5 369 7.72E-44 T 11-11-2016 IPR020846 Major facilitator superfamily domain TW_RS03080 000004b119bf49e30e98721797a8702f 379 Pfam PF07690 Major Facilitator Superfamily 6 334 5.3E-31 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TW_RS03565 099985435da3711db4401fb172d80108 295 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 286 8.4E-54 T 11-11-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 TW_RS03565 099985435da3711db4401fb172d80108 295 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 9.3E-35 T 11-11-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 TW_RS03565 099985435da3711db4401fb172d80108 295 SUPERFAMILY SSF51735 122 285 6.4E-37 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS03565 099985435da3711db4401fb172d80108 295 Gene3D G3DSA:3.40.50.720 139 269 3.4E-40 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS03565 099985435da3711db4401fb172d80108 295 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 11-11-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 TW_RS03565 099985435da3711db4401fb172d80108 295 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 288 33.776 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 TW_RS03565 099985435da3711db4401fb172d80108 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 4.0E-65 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 TW_RS03565 099985435da3711db4401fb172d80108 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 261 279 4.0E-65 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 TW_RS03565 099985435da3711db4401fb172d80108 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 4.0E-65 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 TW_RS03565 099985435da3711db4401fb172d80108 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 4.0E-65 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 TW_RS03565 099985435da3711db4401fb172d80108 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 4.0E-65 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 TW_RS03565 099985435da3711db4401fb172d80108 295 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 4.0E-65 T 11-11-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 TW_RS03565 099985435da3711db4401fb172d80108 295 SUPERFAMILY SSF53223 2 121 4.32E-34 T 11-11-2016 TW_RS03565 099985435da3711db4401fb172d80108 295 Gene3D G3DSA:3.40.192.10 7 138 1.4E-41 T 11-11-2016 TW_RS01835 7a1636134eb66513a5938a227fe2cc37 94 SUPERFAMILY SSF51344 3 84 7.59E-16 T 11-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 TW_RS01835 7a1636134eb66513a5938a227fe2cc37 94 Gene3D G3DSA:2.60.15.10 3 84 1.9E-15 T 11-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 TW_RS01835 7a1636134eb66513a5938a227fe2cc37 94 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 82 4.3E-15 T 11-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 TW_RS01835 7a1636134eb66513a5938a227fe2cc37 94 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 20 80 3.0E-8 T 11-11-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 Reactome: R-HSA-163210 TW_RS02325 7d5b32bc4b19ca7ddebb1b48d4662ed1 100 Gene3D G3DSA:2.102.10.10 2 99 1.4E-30 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TW_RS02325 7d5b32bc4b19ca7ddebb1b48d4662ed1 100 SUPERFAMILY SSF50022 2 99 6.81E-31 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TW_RS02325 7d5b32bc4b19ca7ddebb1b48d4662ed1 100 Pfam PF00355 Rieske [2Fe-2S] domain 2 87 2.1E-20 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TW_RS01625 93730399412f6623de8e461aaa934ca3 220 PIRSF PIRSF016262 3 218 9.1E-57 T 11-11-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TW_RS01625 93730399412f6623de8e461aaa934ca3 220 Pfam PF03099 Biotin/lipoate A/B protein ligase family 65 163 1.6E-9 T 11-11-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 TW_RS01625 93730399412f6623de8e461aaa934ca3 220 SUPERFAMILY SSF55681 5 212 1.66E-55 T 11-11-2016 TW_RS01625 93730399412f6623de8e461aaa934ca3 220 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 34 202 8.8E-42 T 11-11-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TW_RS01625 93730399412f6623de8e461aaa934ca3 220 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 78 130 6.0E-24 T 11-11-2016 TW_RS01625 93730399412f6623de8e461aaa934ca3 220 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 74 89 - T 11-11-2016 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TW_RS01625 93730399412f6623de8e461aaa934ca3 220 Gene3D G3DSA:3.90.1550.10 10 210 2.4E-64 T 11-11-2016 TW_RS01625 93730399412f6623de8e461aaa934ca3 220 Hamap MF_00013 Octanoyltransferase [lipB]. 3 213 32.375 T 11-11-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TW_RS01400 464b140edd5be253770a9bd6b8e89863 461 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 4 458 5.4E-145 T 11-11-2016 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 TW_RS01400 464b140edd5be253770a9bd6b8e89863 461 SUPERFAMILY SSF51230 2 84 1.44E-22 T 11-11-2016 IPR011053 Single hybrid motif TW_RS01400 464b140edd5be253770a9bd6b8e89863 461 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 11-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TW_RS01400 464b140edd5be253770a9bd6b8e89863 461 Gene3D G3DSA:2.40.50.100 3 85 4.0E-24 T 11-11-2016 TW_RS01400 464b140edd5be253770a9bd6b8e89863 461 Pfam PF02817 e3 binding domain 157 191 3.3E-12 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 TW_RS01400 464b140edd5be253770a9bd6b8e89863 461 Pfam PF00364 Biotin-requiring enzyme 4 76 6.8E-18 T 11-11-2016 IPR000089 Biotin/lipoyl attachment TW_RS01400 464b140edd5be253770a9bd6b8e89863 461 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 230 456 1.8E-70 T 11-11-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 TW_RS01400 464b140edd5be253770a9bd6b8e89863 461 SUPERFAMILY SSF47005 150 192 4.19E-10 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 TW_RS01400 464b140edd5be253770a9bd6b8e89863 461 Gene3D G3DSA:4.10.320.10 150 192 1.6E-14 T 11-11-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 TW_RS01400 464b140edd5be253770a9bd6b8e89863 461 Gene3D G3DSA:3.30.559.10 227 456 1.9E-72 T 11-11-2016 IPR023213 Chloramphenicol acetyltransferase-like domain Reactome: R-HSA-389661 TW_RS01400 464b140edd5be253770a9bd6b8e89863 461 SUPERFAMILY SSF52777 229 456 8.53E-75 T 11-11-2016 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 193 3.3E-50 T 11-11-2016 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 217 262 4.2E-8 T 11-11-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 SUPERFAMILY SSF54782 211 319 6.93E-11 T 11-11-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 Gene3D G3DSA:3.30.160.40 213 320 6.8E-13 T 11-11-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 221 237 - T 11-11-2016 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 PRINTS PR00151 Porphobilinogen deaminase signature 220 237 6.3E-22 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 PRINTS PR00151 Porphobilinogen deaminase signature 64 83 6.3E-22 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 PRINTS PR00151 Porphobilinogen deaminase signature 131 148 6.3E-22 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 PRINTS PR00151 Porphobilinogen deaminase signature 112 129 6.3E-22 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 302 6.9E-95 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 PIRSF PIRSF001438 1 321 7.3E-85 T 11-11-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 SUPERFAMILY SSF53850 2 194 2.71E-53 T 11-11-2016 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 Gene3D G3DSA:3.40.190.10 99 185 4.2E-29 T 11-11-2016 TW_RS04050 c34d6233c0558772337e5cf2081ac387 321 Gene3D G3DSA:3.40.190.10 2 98 2.9E-24 T 11-11-2016 TW_RS02120 cfd74e89cbaed31d1ab272cb367e5fdf 315 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 89 2.5E-23 T 11-11-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TW_RS02120 cfd74e89cbaed31d1ab272cb367e5fdf 315 Gene3D G3DSA:3.40.192.10 6 96 2.7E-33 T 11-11-2016 TW_RS02120 cfd74e89cbaed31d1ab272cb367e5fdf 315 Gene3D G3DSA:3.40.192.10 147 157 2.7E-33 T 11-11-2016 TW_RS02120 cfd74e89cbaed31d1ab272cb367e5fdf 315 SUPERFAMILY SSF53223 4 93 3.05E-24 T 11-11-2016 TW_RS02120 cfd74e89cbaed31d1ab272cb367e5fdf 315 SUPERFAMILY SSF51735 153 292 2.08E-12 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS02120 cfd74e89cbaed31d1ab272cb367e5fdf 315 Gene3D G3DSA:3.40.50.720 158 297 2.8E-16 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS03785 1dc51cc44e2ff2d6f1ab463333e53902 427 SUPERFAMILY SSF53686 17 330 6.29E-85 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TW_RS03785 1dc51cc44e2ff2d6f1ab463333e53902 427 Gene3D G3DSA:3.40.50.1100 73 338 3.0E-69 T 11-11-2016 TW_RS03785 1dc51cc44e2ff2d6f1ab463333e53902 427 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 25 423 7.6E-116 T 11-11-2016 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 TW_RS03785 1dc51cc44e2ff2d6f1ab463333e53902 427 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 322 1.5E-71 T 11-11-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme TW_RS03785 1dc51cc44e2ff2d6f1ab463333e53902 427 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 46 59 - T 11-11-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TW_RS03785 1dc51cc44e2ff2d6f1ab463333e53902 427 SUPERFAMILY SSF55021 342 424 1.47E-5 T 11-11-2016 TW_RS02675 65e20c815f17d72202589f6c037277d6 183 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 31.825 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TW_RS02675 65e20c815f17d72202589f6c037277d6 183 SUPERFAMILY SSF53098 1 156 3.49E-39 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TW_RS02675 65e20c815f17d72202589f6c037277d6 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 2.6E-21 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TW_RS02675 65e20c815f17d72202589f6c037277d6 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 2.6E-21 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TW_RS02675 65e20c815f17d72202589f6c037277d6 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 2.6E-21 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TW_RS02675 65e20c815f17d72202589f6c037277d6 183 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 2.6E-21 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TW_RS02675 65e20c815f17d72202589f6c037277d6 183 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 151 2.3E-33 T 11-11-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TW_RS02675 65e20c815f17d72202589f6c037277d6 183 Gene3D G3DSA:3.30.420.10 1 155 6.2E-42 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TW_RS02675 65e20c815f17d72202589f6c037277d6 183 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 11-11-2016 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 TW_RS01635 4f115bc4d73798fd6ba5520fe509003a 148 SUPERFAMILY SSF54565 2 88 1.22E-32 T 11-11-2016 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01635 4f115bc4d73798fd6ba5520fe509003a 148 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 2.7E-31 T 11-11-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01635 4f115bc4d73798fd6ba5520fe509003a 148 Gene3D G3DSA:3.30.1320.10 2 82 5.6E-32 T 11-11-2016 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01635 4f115bc4d73798fd6ba5520fe509003a 148 Pfam PF00886 Ribosomal protein S16 9 67 8.4E-24 T 11-11-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01635 4f115bc4d73798fd6ba5520fe509003a 148 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 11-11-2016 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01635 4f115bc4d73798fd6ba5520fe509003a 148 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 23.391 T 11-11-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 PRINTS PR00981 Seryl-tRNA synthetase signature 271 284 1.3E-27 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 PRINTS PR00981 Seryl-tRNA synthetase signature 311 324 1.3E-27 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 PRINTS PR00981 Seryl-tRNA synthetase signature 259 271 1.3E-27 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 PRINTS PR00981 Seryl-tRNA synthetase signature 328 344 1.3E-27 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 PRINTS PR00981 Seryl-tRNA synthetase signature 346 362 1.3E-27 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 Gene3D G3DSA:1.10.287.40 2 103 6.0E-15 T 11-11-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 415 37.515 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 408 7.5E-126 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 PIRSF PIRSF001529 1 417 2.1E-131 T 11-11-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 SUPERFAMILY SSF55681 112 415 2.55E-85 T 11-11-2016 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 220 393 1.0E-27 T 11-11-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 1.1E-14 T 11-11-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 Gene3D G3DSA:3.30.930.10 104 413 1.8E-115 T 11-11-2016 TW_RS04010 a9ae64b3e9f92f6bc0d3f554da653e34 417 SUPERFAMILY SSF46589 2 111 2.04E-16 T 11-11-2016 IPR010978 tRNA-binding arm GO:0000166 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 Gene3D G3DSA:1.10.10.350 399 476 1.0E-15 T 11-11-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 6 478 9.9E-128 T 11-11-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 Gene3D G3DSA:3.40.50.620 194 248 2.5E-43 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 Gene3D G3DSA:3.40.50.620 6 70 2.5E-43 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 6 478 29.947 T 11-11-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 Gene3D G3DSA:1.10.1160.10 251 333 1.8E-24 T 11-11-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 Gene3D G3DSA:3.90.800.10 71 192 2.4E-29 T 11-11-2016 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 321 3.5E-76 T 11-11-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 SUPERFAMILY SSF48163 318 477 1.01E-29 T 11-11-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 SUPERFAMILY SSF52374 6 316 6.7E-92 T 11-11-2016 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 9 21 1.9E-22 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 38 51 1.9E-22 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 23 34 1.9E-22 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 192 202 1.9E-22 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 TW_RS02985 69c8688c1be8ba0931b0a4dca936ddf6 480 PRINTS PR00987 Glutamyl-tRNA synthetase signature 208 216 1.9E-22 T 11-11-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 TW_RS04355 7c6bc38808de052fa57200ae50408b48 429 Gene3D G3DSA:3.40.440.10 3 93 1.1E-69 T 11-11-2016 TW_RS04355 7c6bc38808de052fa57200ae50408b48 429 Gene3D G3DSA:3.40.440.10 195 264 1.1E-69 T 11-11-2016 TW_RS04355 7c6bc38808de052fa57200ae50408b48 429 Gene3D G3DSA:1.10.300.10 101 194 1.0E-31 T 11-11-2016 TW_RS04355 7c6bc38808de052fa57200ae50408b48 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 11-11-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TW_RS04355 7c6bc38808de052fa57200ae50408b48 429 Pfam PF00709 Adenylosuccinate synthetase 4 421 5.0E-170 T 11-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TW_RS04355 7c6bc38808de052fa57200ae50408b48 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 187.167 T 11-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TW_RS04355 7c6bc38808de052fa57200ae50408b48 429 Gene3D G3DSA:3.90.170.10 265 423 5.5E-63 T 11-11-2016 TW_RS04355 7c6bc38808de052fa57200ae50408b48 429 SMART SM00788 3 422 2.9E-272 T 11-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TW_RS04355 7c6bc38808de052fa57200ae50408b48 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 422 2.3E-157 T 11-11-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TW_RS04355 7c6bc38808de052fa57200ae50408b48 429 SUPERFAMILY SSF52540 3 424 7.86E-168 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04355 7c6bc38808de052fa57200ae50408b48 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 11-11-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TW_RS04300 b16827cf9425e87accf7bef3724d7a18 136 Pfam PF04977 Septum formation initiator 15 92 2.4E-16 T 11-11-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 TW_RS00695 04594a4248f732a8a2f43099a13e5065 455 SUPERFAMILY SSF51182 4 313 9.19E-61 T 11-11-2016 IPR011051 RmlC-like cupin domain TW_RS00695 04594a4248f732a8a2f43099a13e5065 455 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 6 311 3.0E-48 T 11-11-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TW_RS00695 04594a4248f732a8a2f43099a13e5065 455 Gene3D G3DSA:2.60.120.10 5 150 1.2E-51 T 11-11-2016 IPR014710 RmlC-like jelly roll fold TW_RS00695 04594a4248f732a8a2f43099a13e5065 455 Gene3D G3DSA:2.60.120.10 216 277 1.2E-51 T 11-11-2016 IPR014710 RmlC-like jelly roll fold TW_RS00695 04594a4248f732a8a2f43099a13e5065 455 PRINTS PR00714 Phosphomannose isomerase type I signature 9 27 4.9E-25 T 11-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TW_RS00695 04594a4248f732a8a2f43099a13e5065 455 PRINTS PR00714 Phosphomannose isomerase type I signature 36 51 4.9E-25 T 11-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TW_RS00695 04594a4248f732a8a2f43099a13e5065 455 PRINTS PR00714 Phosphomannose isomerase type I signature 217 236 4.9E-25 T 11-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TW_RS00695 04594a4248f732a8a2f43099a13e5065 455 PRINTS PR00714 Phosphomannose isomerase type I signature 236 255 4.9E-25 T 11-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TW_RS00695 04594a4248f732a8a2f43099a13e5065 455 PRINTS PR00714 Phosphomannose isomerase type I signature 110 133 4.9E-25 T 11-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TW_RS00695 04594a4248f732a8a2f43099a13e5065 455 PRINTS PR00714 Phosphomannose isomerase type I signature 255 274 4.9E-25 T 11-11-2016 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TW_RS00695 04594a4248f732a8a2f43099a13e5065 455 Pfam PF01238 Phosphomannose isomerase type I 7 146 1.0E-24 T 11-11-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TW_RS00695 04594a4248f732a8a2f43099a13e5065 455 Pfam PF01238 Phosphomannose isomerase type I 195 286 5.2E-14 T 11-11-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 TW_RS01985 55f63c94f1ed5904f720c25efaceae57 294 SMART SM01232 164 256 2.9E-20 T 11-11-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TW_RS01985 55f63c94f1ed5904f720c25efaceae57 294 SUPERFAMILY SSF57716 258 293 3.99E-8 T 11-11-2016 TW_RS01985 55f63c94f1ed5904f720c25efaceae57 294 SUPERFAMILY SSF81624 120 165 1.96E-17 T 11-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TW_RS01985 55f63c94f1ed5904f720c25efaceae57 294 SUPERFAMILY SSF81624 2 78 1.96E-17 T 11-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TW_RS01985 55f63c94f1ed5904f720c25efaceae57 294 Gene3D G3DSA:1.10.8.50 164 293 8.5E-33 T 11-11-2016 TW_RS01985 55f63c94f1ed5904f720c25efaceae57 294 SUPERFAMILY SSF46946 163 248 5.89E-23 T 11-11-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TW_RS01985 55f63c94f1ed5904f720c25efaceae57 294 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 164 251 6.0E-18 T 11-11-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TW_RS01985 55f63c94f1ed5904f720c25efaceae57 294 SMART SM00898 2 142 4.3E-10 T 11-11-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TW_RS01985 55f63c94f1ed5904f720c25efaceae57 294 Gene3D G3DSA:3.20.190.10 2 78 7.4E-10 T 11-11-2016 TW_RS03435 3986754c0080623b4da93ca020180d80 741 Pfam PF09397 Ftsk gamma domain 662 720 1.8E-22 T 11-11-2016 IPR018541 FtsK gamma domain TW_RS03435 3986754c0080623b4da93ca020180d80 741 Pfam PF01580 FtsK/SpoIIIE family 373 561 1.8E-55 T 11-11-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TW_RS03435 3986754c0080623b4da93ca020180d80 741 SUPERFAMILY SSF46785 658 724 2.04E-17 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS03435 3986754c0080623b4da93ca020180d80 741 SUPERFAMILY SSF52540 342 634 9.31E-41 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03435 3986754c0080623b4da93ca020180d80 741 SMART SM00382 399 594 0.0027 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS03435 3986754c0080623b4da93ca020180d80 741 Gene3D G3DSA:3.40.50.300 341 627 2.5E-75 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03435 3986754c0080623b4da93ca020180d80 741 SMART SM00843 657 722 4.8E-29 T 11-11-2016 IPR018541 FtsK gamma domain TW_RS03825 c64f8796deeaf0010689ef69567075dc 215 Gene3D G3DSA:3.90.870.10 3 202 7.7E-82 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TW_RS03825 c64f8796deeaf0010689ef69567075dc 215 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 197 7.8E-76 T 11-11-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS03825 c64f8796deeaf0010689ef69567075dc 215 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 3 197 2.0E-65 T 11-11-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TW_RS03825 c64f8796deeaf0010689ef69567075dc 215 SUPERFAMILY SSF55821 3 201 3.43E-72 T 11-11-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain TW_RS01840 8e3feea5b99bce2149fd16be0531f660 90 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 8 90 5.8E-35 T 11-11-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01840 8e3feea5b99bce2149fd16be0531f660 90 Gene3D G3DSA:1.10.287.10 7 90 3.3E-35 T 11-11-2016 IPR009068 S15/NS1, RNA-binding TW_RS01840 8e3feea5b99bce2149fd16be0531f660 90 SUPERFAMILY SSF47060 7 90 7.36E-32 T 11-11-2016 IPR009068 S15/NS1, RNA-binding TW_RS01840 8e3feea5b99bce2149fd16be0531f660 90 SMART SM01387 9 89 1.8E-46 T 11-11-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01840 8e3feea5b99bce2149fd16be0531f660 90 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 12 89 3.0E-28 T 11-11-2016 TW_RS01840 8e3feea5b99bce2149fd16be0531f660 90 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 1 90 21.178 T 11-11-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01840 8e3feea5b99bce2149fd16be0531f660 90 Pfam PF00312 Ribosomal protein S15 11 89 1.6E-34 T 11-11-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03305 618f6e48d51d9388a1df017a21dda6c8 336 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 48 333 1.3E-72 T 11-11-2016 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TW_RS03305 618f6e48d51d9388a1df017a21dda6c8 336 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 11 333 37.169 T 11-11-2016 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 TW_RS03305 618f6e48d51d9388a1df017a21dda6c8 336 SUPERFAMILY SSF55681 95 334 3.78E-67 T 11-11-2016 TW_RS03305 618f6e48d51d9388a1df017a21dda6c8 336 Gene3D G3DSA:3.30.930.10 13 334 2.3E-97 T 11-11-2016 TW_RS03305 618f6e48d51d9388a1df017a21dda6c8 336 SUPERFAMILY SSF46589 15 100 5.75E-11 T 11-11-2016 IPR010978 tRNA-binding arm GO:0000166 TW_RS03305 618f6e48d51d9388a1df017a21dda6c8 336 Pfam PF01409 tRNA synthetases class II core domain (F) 95 333 2.1E-86 T 11-11-2016 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TW_RS03305 618f6e48d51d9388a1df017a21dda6c8 336 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 23 89 1.1E-8 T 11-11-2016 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TW_RS04125 53d81107243fc3968506cd63aa2c1d01 130 SMART SM00422 7 75 8.2E-16 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TW_RS04125 53d81107243fc3968506cd63aa2c1d01 130 Gene3D G3DSA:1.10.1660.10 8 94 3.0E-18 T 11-11-2016 TW_RS04125 53d81107243fc3968506cd63aa2c1d01 130 SUPERFAMILY SSF46955 7 91 3.11E-15 T 11-11-2016 IPR009061 Putative DNA-binding domain TW_RS04125 53d81107243fc3968506cd63aa2c1d01 130 Pfam PF13411 MerR HTH family regulatory protein 8 72 4.6E-14 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TW_RS02840 43b052bd4d596d3c45116e314ff0887c 225 Gene3D G3DSA:1.10.1660.10 13 86 9.3E-15 T 11-11-2016 TW_RS02840 43b052bd4d596d3c45116e314ff0887c 225 Pfam PF00376 MerR family regulatory protein 13 54 1.6E-11 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TW_RS02840 43b052bd4d596d3c45116e314ff0887c 225 SMART SM00422 12 86 1.4E-13 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TW_RS02840 43b052bd4d596d3c45116e314ff0887c 225 SUPERFAMILY SSF46955 13 89 1.14E-10 T 11-11-2016 IPR009061 Putative DNA-binding domain TW_RS00965 68b90b7f4eedf207412f7bb193342c9a 401 SUPERFAMILY SSF53067 3 121 6.47E-29 T 11-11-2016 TW_RS00965 68b90b7f4eedf207412f7bb193342c9a 401 Gene3D G3DSA:3.30.420.40 3 121 3.3E-36 T 11-11-2016 TW_RS00965 68b90b7f4eedf207412f7bb193342c9a 401 Gene3D G3DSA:3.30.420.40 181 214 3.3E-36 T 11-11-2016 TW_RS00965 68b90b7f4eedf207412f7bb193342c9a 401 SUPERFAMILY SSF53067 183 372 3.74E-33 T 11-11-2016 TW_RS00965 68b90b7f4eedf207412f7bb193342c9a 401 SUPERFAMILY SSF53067 102 123 3.74E-33 T 11-11-2016 TW_RS00965 68b90b7f4eedf207412f7bb193342c9a 401 Gene3D G3DSA:3.30.420.40 314 354 3.6E-5 T 11-11-2016 TW_RS00965 68b90b7f4eedf207412f7bb193342c9a 401 Pfam PF00814 Glycoprotease family 23 122 1.0E-33 T 11-11-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TW_RS00965 68b90b7f4eedf207412f7bb193342c9a 401 Pfam PF00814 Glycoprotease family 188 370 6.5E-48 T 11-11-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TW_RS00965 68b90b7f4eedf207412f7bb193342c9a 401 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 9.8E-22 T 11-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TW_RS00965 68b90b7f4eedf207412f7bb193342c9a 401 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 5 18 9.8E-22 T 11-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TW_RS00965 68b90b7f4eedf207412f7bb193342c9a 401 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 9.8E-22 T 11-11-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TW_RS00965 68b90b7f4eedf207412f7bb193342c9a 401 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 2 396 53.916 T 11-11-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TW_RS00280 154e32e03b258180a82945121fc05656 686 SUPERFAMILY SSF52540 389 679 5.18E-52 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00280 154e32e03b258180a82945121fc05656 686 Hamap MF_00195 GTPase Der [der]. 254 682 32.626 T 11-11-2016 IPR016484 GTP-binding protein EngA GO:0005525 TW_RS00280 154e32e03b258180a82945121fc05656 686 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 426 588 2.5E-18 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TW_RS00280 154e32e03b258180a82945121fc05656 686 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 256 410 7.6E-23 T 11-11-2016 IPR005225 Small GTP-binding protein domain GO:0005525 TW_RS00280 154e32e03b258180a82945121fc05656 686 Hamap MF_00238 Cytidylate kinase [cmk]. 5 231 23.318 T 11-11-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 TW_RS00280 154e32e03b258180a82945121fc05656 686 Pfam PF02224 Cytidylate kinase 7 228 5.2E-42 T 11-11-2016 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 TW_RS00280 154e32e03b258180a82945121fc05656 686 Gene3D G3DSA:3.40.50.300 254 413 1.8E-39 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00280 154e32e03b258180a82945121fc05656 686 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 256 679 7.6E-147 T 11-11-2016 IPR016484 GTP-binding protein EngA GO:0005525 TW_RS00280 154e32e03b258180a82945121fc05656 686 SUPERFAMILY SSF52540 256 414 6.95E-39 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00280 154e32e03b258180a82945121fc05656 686 Pfam PF01926 50S ribosome-binding GTPase 257 371 6.8E-22 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS00280 154e32e03b258180a82945121fc05656 686 Pfam PF01926 50S ribosome-binding GTPase 427 545 1.2E-22 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS00280 154e32e03b258180a82945121fc05656 686 SUPERFAMILY SSF52540 118 229 7.63E-20 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00280 154e32e03b258180a82945121fc05656 686 SUPERFAMILY SSF52540 6 70 7.63E-20 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00280 154e32e03b258180a82945121fc05656 686 Gene3D G3DSA:3.40.50.300 6 228 1.5E-53 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00280 154e32e03b258180a82945121fc05656 686 Gene3D G3DSA:3.40.50.300 425 606 5.9E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00280 154e32e03b258180a82945121fc05656 686 Gene3D G3DSA:3.30.300.20 607 679 2.5E-21 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta TW_RS00280 154e32e03b258180a82945121fc05656 686 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 477 492 5.7E-7 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS00280 154e32e03b258180a82945121fc05656 686 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 428 448 5.7E-7 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS00280 154e32e03b258180a82945121fc05656 686 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 601 679 6.3E-19 T 11-11-2016 IPR032859 GTPase Der, C-terminal KH-domain-like TW_RS02680 bbfb61f56800449f61c688029d867c2e 252 Gene3D G3DSA:3.30.1270.10 219 248 5.2E-27 T 11-11-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02680 bbfb61f56800449f61c688029d867c2e 252 Gene3D G3DSA:3.30.1270.10 84 136 5.2E-27 T 11-11-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02680 bbfb61f56800449f61c688029d867c2e 252 SUPERFAMILY SSF75625 3 245 2.22E-77 T 11-11-2016 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02680 bbfb61f56800449f61c688029d867c2e 252 Gene3D G3DSA:1.10.10.200 1 79 1.7E-32 T 11-11-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like TW_RS02680 bbfb61f56800449f61c688029d867c2e 252 Gene3D G3DSA:3.30.70.980 137 211 2.6E-18 T 11-11-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02680 bbfb61f56800449f61c688029d867c2e 252 Pfam PF01709 Transcriptional regulator 5 244 9.1E-78 T 11-11-2016 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02680 bbfb61f56800449f61c688029d867c2e 252 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 244 8.8E-80 T 11-11-2016 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02680 bbfb61f56800449f61c688029d867c2e 252 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 246 31.07 T 11-11-2016 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS01140 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 Gene3D G3DSA:2.40.30.10 154 204 2.1E-8 T 11-11-2016 TW_RS01140 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 Gene3D G3DSA:2.40.30.10 4 42 2.1E-8 T 11-11-2016 TW_RS01140 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 5 200 8.8E-78 T 11-11-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01140 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 Pfam PF00297 Ribosomal protein L3 95 178 5.8E-18 T 11-11-2016 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01140 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 Gene3D G3DSA:4.10.960.10 86 153 2.5E-28 T 11-11-2016 TW_RS01140 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 203 36.625 T 11-11-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01140 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 ProSitePatterns PS00474 Ribosomal protein L3 signature. 97 120 - T 11-11-2016 IPR019926 Ribosomal protein L3, conserved site TW_RS01140 4077cf7a235df4ef5cdf8cfd6bea4ef1 210 SUPERFAMILY SSF50447 4 204 6.18E-72 T 11-11-2016 IPR009000 Translation protein, beta-barrel domain TW_RS00740 b924e458f903fe272d9ad29c4b626a9b 248 Pfam PF08666 SAF domain 39 98 1.2E-4 T 11-11-2016 IPR013974 SAF domain Reactome: R-HSA-4085001 TW_RS03580 7f84d4438a548e902ed8174db0023830 121 SUPERFAMILY SSF51230 5 120 1.78E-31 T 11-11-2016 IPR011053 Single hybrid motif TW_RS03580 7f84d4438a548e902ed8174db0023830 121 Pfam PF01597 Glycine cleavage H-protein 7 120 1.2E-31 T 11-11-2016 IPR002930 Glycine cleavage system H-protein TW_RS03580 7f84d4438a548e902ed8174db0023830 121 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 11-11-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TW_RS03580 7f84d4438a548e902ed8174db0023830 121 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 120 22.411 T 11-11-2016 IPR002930 Glycine cleavage system H-protein TW_RS03580 7f84d4438a548e902ed8174db0023830 121 Gene3D G3DSA:2.40.50.100 6 121 1.2E-36 T 11-11-2016 TW_RS01620 e8e45328b007f029abffba6eaa5593c6 323 SMART SM00729 62 268 8.6E-12 T 11-11-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 TW_RS01620 e8e45328b007f029abffba6eaa5593c6 323 Gene3D G3DSA:3.20.20.70 30 292 1.4E-63 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS01620 e8e45328b007f029abffba6eaa5593c6 323 PIRSF PIRSF005963 1 313 7.2E-127 T 11-11-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TW_RS01620 e8e45328b007f029abffba6eaa5593c6 323 TIGRFAM TIGR00510 lipA: lipoyl synthase 11 297 8.5E-101 T 11-11-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TW_RS01620 e8e45328b007f029abffba6eaa5593c6 323 Pfam PF04055 Radical SAM superfamily 71 226 1.4E-10 T 11-11-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 TW_RS01620 e8e45328b007f029abffba6eaa5593c6 323 Hamap MF_00206 Lipoyl synthase [lipA]. 1 298 134.763 T 11-11-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TW_RS01620 e8e45328b007f029abffba6eaa5593c6 323 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 15 51 2.0E-6 T 11-11-2016 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TW_RS01620 e8e45328b007f029abffba6eaa5593c6 323 SUPERFAMILY SSF102114 29 287 5.23E-60 T 11-11-2016 TW_RS01195 5721aee4759bb7c1d3865b1f8610249a 113 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 111 2.8E-26 T 11-11-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01195 5721aee4759bb7c1d3865b1f8610249a 113 SUPERFAMILY SSF50104 3 109 4.81E-22 T 11-11-2016 IPR008991 Translation protein SH3-like domain TW_RS01195 5721aee4759bb7c1d3865b1f8610249a 113 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 42 111 4.6E-19 T 11-11-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01195 5721aee4759bb7c1d3865b1f8610249a 113 Gene3D G3DSA:2.30.30.30 2 96 1.6E-18 T 11-11-2016 IPR014722 Ribosomal protein L2 domain 2 TW_RS01195 5721aee4759bb7c1d3865b1f8610249a 113 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 3 106 19.32 T 11-11-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS00165 17069d3884c74e0c4f28f0ccaec7d225 327 Gene3D G3DSA:3.40.50.720 2 184 1.7E-68 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00165 17069d3884c74e0c4f28f0ccaec7d225 327 SUPERFAMILY SSF51735 1 321 2.49E-97 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00165 17069d3884c74e0c4f28f0ccaec7d225 327 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 4 321 1.5E-136 T 11-11-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 TW_RS00165 17069d3884c74e0c4f28f0ccaec7d225 327 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 307 6.1E-83 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00165 17069d3884c74e0c4f28f0ccaec7d225 327 Gene3D G3DSA:3.90.25.10 185 322 1.5E-49 T 11-11-2016 TW_RS00165 17069d3884c74e0c4f28f0ccaec7d225 327 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 11-11-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TW_RS01230 3f619e4681045ed40ce7f70b21c329c3 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 144 1.7E-24 T 11-11-2016 IPR021131 Ribosomal protein L18e/L15P TW_RS01230 3f619e4681045ed40ce7f70b21c329c3 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 6 146 16.248 T 11-11-2016 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 TW_RS01230 3f619e4681045ed40ce7f70b21c329c3 147 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 5 143 1.4E-36 T 11-11-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01230 3f619e4681045ed40ce7f70b21c329c3 147 Gene3D G3DSA:3.100.10.10 34 145 5.0E-22 T 11-11-2016 TW_RS01230 3f619e4681045ed40ce7f70b21c329c3 147 SUPERFAMILY SSF52080 7 144 4.06E-33 T 11-11-2016 IPR021131 Ribosomal protein L18e/L15P TW_RS02010 aed819376d720f7d0337927084bfced8 132 SUPERFAMILY SSF82649 2 131 7.32E-24 T 11-11-2016 TW_RS02010 aed819376d720f7d0337927084bfced8 132 Pfam PF02657 Fe-S metabolism associated domain 17 130 4.8E-20 T 11-11-2016 IPR003808 Fe-S metabolism associated domain, SufE-like TW_RS02010 aed819376d720f7d0337927084bfced8 132 Gene3D G3DSA:3.90.1010.10 2 130 2.2E-21 T 11-11-2016 TW_RS02650 031fccfa29f2d2e33c367635d36a1696 322 PRINTS PR01755 Bacterial translocase SecF protein signature 204 222 6.3E-17 T 11-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TW_RS02650 031fccfa29f2d2e33c367635d36a1696 322 PRINTS PR01755 Bacterial translocase SecF protein signature 237 252 6.3E-17 T 11-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TW_RS02650 031fccfa29f2d2e33c367635d36a1696 322 PRINTS PR01755 Bacterial translocase SecF protein signature 46 61 6.3E-17 T 11-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TW_RS02650 031fccfa29f2d2e33c367635d36a1696 322 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 47 294 3.3E-60 T 11-11-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 TW_RS02650 031fccfa29f2d2e33c367635d36a1696 322 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 18 305 24.12 T 11-11-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 TW_RS02650 031fccfa29f2d2e33c367635d36a1696 322 Pfam PF02355 Protein export membrane protein 114 301 1.1E-53 T 11-11-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TW_RS02650 031fccfa29f2d2e33c367635d36a1696 322 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 61 291 4.4E-46 T 11-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TW_RS02650 031fccfa29f2d2e33c367635d36a1696 322 SUPERFAMILY SSF82866 84 304 1.83E-35 T 11-11-2016 TW_RS02650 031fccfa29f2d2e33c367635d36a1696 322 Gene3D G3DSA:1.20.1640.10 106 311 2.0E-27 T 11-11-2016 TW_RS02975 f8ebf25433c939d789b7312b4ed40275 103 Pfam PF05345 Putative Ig domain 18 67 2.4E-9 T 11-11-2016 IPR008009 Putative Ig TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 ProSitePatterns PS00905 GTP1/OBG family signature. 217 230 - T 11-11-2016 IPR006074 GTP1/OBG, conserved site GO:0005525 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 Pfam PF01926 50S ribosome-binding GTPase 166 292 4.0E-24 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 Pfam PF01018 GTP1/OBG 9 162 2.2E-48 T 11-11-2016 IPR006169 GTP1/OBG domain GO:0005525 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 Gene3D G3DSA:3.40.50.300 165 350 7.2E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 9 339 5.2E-120 T 11-11-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 369 433 2.8E-25 T 11-11-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 SUPERFAMILY SSF102741 369 434 6.93E-19 T 11-11-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 Gene3D G3DSA:2.70.210.12 8 160 1.6E-45 T 11-11-2016 IPR006169 GTP1/OBG domain GO:0005525 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 SUPERFAMILY SSF82051 9 162 1.57E-44 T 11-11-2016 IPR006169 GTP1/OBG domain GO:0005525 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 Hamap MF_01454 GTPase Obg [obg]. 8 342 42.366 T 11-11-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 SUPERFAMILY SSF52540 166 345 4.02E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 232 250 6.8E-35 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 215 230 6.8E-35 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 188 206 6.8E-35 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 167 187 6.8E-35 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS01580 0b5dd0250361e8a473afd3d18568b4b9 445 Pfam PF09269 Domain of unknown function (DUF1967) 370 432 3.0E-22 T 11-11-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 TW_RS02780 f0e98690a09e02809d97480cf6218995 274 Gene3D G3DSA:1.10.760.10 154 235 3.7E-15 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 TW_RS02780 f0e98690a09e02809d97480cf6218995 274 Gene3D G3DSA:1.10.760.10 52 143 2.2E-17 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 TW_RS02780 f0e98690a09e02809d97480cf6218995 274 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 158 228 2.2E-10 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 TW_RS02780 f0e98690a09e02809d97480cf6218995 274 Pfam PF00034 Cytochrome c 63 138 1.2E-9 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 TW_RS02780 f0e98690a09e02809d97480cf6218995 274 SUPERFAMILY SSF46626 139 230 6.94E-22 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 TW_RS02780 f0e98690a09e02809d97480cf6218995 274 SUPERFAMILY SSF46626 29 141 8.09E-20 T 11-11-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 TW_RS02780 f0e98690a09e02809d97480cf6218995 274 PIRSF PIRSF000007 1 273 3.5E-121 T 11-11-2016 IPR009152 Ubiquinol-cytochrome-c reductase, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 TW_RS03425 f09518f304ed8d067e6036e229dee2c7 201 PIRSF PIRSF000847 1 201 5.5E-44 T 11-11-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 TW_RS03425 f09518f304ed8d067e6036e229dee2c7 201 Pfam PF01066 CDP-alcohol phosphatidyltransferase 1 66 9.2E-18 T 11-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TW_RS03425 f09518f304ed8d067e6036e229dee2c7 201 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 2 196 8.6E-37 T 11-11-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668 TW_RS03425 f09518f304ed8d067e6036e229dee2c7 201 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 44 66 - T 11-11-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TW_RS03510 d6362f9824fe6edcca16cc3facc82463 690 Pfam PF07861 WisP family N-Terminal Region 37 272 5.0E-155 T 11-11-2016 IPR012503 WisP, N-terminal TW_RS03510 d6362f9824fe6edcca16cc3facc82463 690 Pfam PF05345 Putative Ig domain 524 568 8.6E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS03510 d6362f9824fe6edcca16cc3facc82463 690 Pfam PF05345 Putative Ig domain 421 465 4.7E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS01340 5eb6dec991bbc5c07d198468a1d661e9 123 Hamap MF_01197 Cell division protein SepF [sepF]. 2 123 17.577 T 11-11-2016 IPR023052 Cell division protein SepF GO:0090529 TW_RS01340 5eb6dec991bbc5c07d198468a1d661e9 123 Pfam PF04472 Protein of unknown function (DUF552) 44 115 5.2E-20 T 11-11-2016 IPR007561 Cell division protein SepF/SepF-related GO:0090529 TW_RS01130 092b9739747120007afcbdb2245800c9 253 SUPERFAMILY SSF52540 48 251 1.18E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01130 092b9739747120007afcbdb2245800c9 253 Gene3D G3DSA:3.40.50.300 65 253 2.6E-68 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01130 092b9739747120007afcbdb2245800c9 253 Gene3D G3DSA:1.20.120.140 1 64 2.6E-14 T 11-11-2016 TW_RS01130 092b9739747120007afcbdb2245800c9 253 SMART SM00382 52 204 3.4E-7 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS01130 092b9739747120007afcbdb2245800c9 253 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 226 239 - T 11-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TW_RS01130 092b9739747120007afcbdb2245800c9 253 Pfam PF00448 SRP54-type protein, GTPase domain 53 252 3.5E-71 T 11-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TW_RS01130 092b9739747120007afcbdb2245800c9 253 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 2 252 1.1E-86 T 11-11-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TW_RS01130 092b9739747120007afcbdb2245800c9 253 SMART SM00962 53 253 5.6E-99 T 11-11-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TW_RS02795 b232249afde73090558412bcddab1339 543 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 23 528 1.1E-209 T 11-11-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TW_RS02795 b232249afde73090558412bcddab1339 543 SUPERFAMILY SSF81442 20 530 7.19E-173 T 11-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 139 151 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 21 46 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 296 311 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 171 189 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 200 219 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 381 400 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 250 271 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 96 120 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 353 371 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 229 250 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 318 339 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 69 92 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 PRINTS PR01165 Cytochrome c oxidase subunit I signature 431 452 2.3E-105 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 31 475 3.4E-148 T 11-11-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 252 306 - T 11-11-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02795 b232249afde73090558412bcddab1339 543 Gene3D G3DSA:1.20.210.10 12 536 1.2E-189 T 11-11-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS00150 c93a785326f06ad57e3a9124d5de1949 180 PIRSF PIRSF001338 13 180 1.4E-60 T 11-11-2016 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 TW_RS00150 c93a785326f06ad57e3a9124d5de1949 180 SUPERFAMILY SSF52255 16 172 4.06E-59 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TW_RS00150 c93a785326f06ad57e3a9124d5de1949 180 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 17 171 6.2E-59 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TW_RS00150 c93a785326f06ad57e3a9124d5de1949 180 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 17 168 28.65 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TW_RS00150 c93a785326f06ad57e3a9124d5de1949 180 Gene3D G3DSA:3.40.50.7700 11 177 4.4E-67 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TW_RS00150 c93a785326f06ad57e3a9124d5de1949 180 Pfam PF00731 AIR carboxylase 17 162 7.9E-61 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TW_RS00150 c93a785326f06ad57e3a9124d5de1949 180 SMART SM01001 15 169 1.0E-80 T 11-11-2016 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TW_RS00770 08eb1b1bac55107358969debccfa4e0e 201 Pfam PF02361 Cobalt transport protein 35 200 1.2E-5 T 11-11-2016 IPR003339 ABC/ECF transporter, transmembrane component TW_RS03995 879c6d32cca170e85be4fe319378469a 337 Gene3D G3DSA:3.90.650.10 170 329 1.5E-47 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain TW_RS03995 879c6d32cca170e85be4fe319378469a 337 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 5 325 1.9E-101 T 11-11-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TW_RS03995 879c6d32cca170e85be4fe319378469a 337 SUPERFAMILY SSF56042 170 330 1.45E-43 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain TW_RS03995 879c6d32cca170e85be4fe319378469a 337 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 336 36.918 T 11-11-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TW_RS03995 879c6d32cca170e85be4fe319378469a 337 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 328 9.7E-22 T 11-11-2016 IPR010918 AIR synthase-related protein, C-terminal domain TW_RS03995 879c6d32cca170e85be4fe319378469a 337 Gene3D G3DSA:3.30.1330.10 19 167 7.7E-49 T 11-11-2016 IPR016188 PurM-like, N-terminal domain TW_RS03995 879c6d32cca170e85be4fe319378469a 337 SUPERFAMILY SSF55326 4 166 1.67E-41 T 11-11-2016 TW_RS03995 879c6d32cca170e85be4fe319378469a 337 Pfam PF00586 AIR synthase related protein, N-terminal domain 58 162 4.7E-16 T 11-11-2016 IPR016188 PurM-like, N-terminal domain TW_RS01930 3dbadd8246a48bb299d13f9e4a0c892d 184 Hamap MF_00045 Oligoribonuclease [orn]. 5 182 35.987 T 11-11-2016 IPR022894 Oligoribonuclease GO:0016788 TW_RS01930 3dbadd8246a48bb299d13f9e4a0c892d 184 SMART SM00479 9 181 6.1E-21 T 11-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III TW_RS01930 3dbadd8246a48bb299d13f9e4a0c892d 184 Pfam PF00929 Exonuclease 11 171 8.4E-23 T 11-11-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III TW_RS01930 3dbadd8246a48bb299d13f9e4a0c892d 184 SUPERFAMILY SSF53098 7 179 2.99E-38 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TW_RS01930 3dbadd8246a48bb299d13f9e4a0c892d 184 Gene3D G3DSA:3.30.420.10 8 179 4.3E-58 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TW_RS02225 7633b149226937876320e73acd693890 257 SMART SM00382 29 237 7.3E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS02225 7633b149226937876320e73acd693890 257 SUPERFAMILY SSF52540 4 243 2.85E-60 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02225 7633b149226937876320e73acd693890 257 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS02225 7633b149226937876320e73acd693890 257 Gene3D G3DSA:3.40.50.300 3 251 1.9E-69 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02225 7633b149226937876320e73acd693890 257 Pfam PF00005 ABC transporter 21 175 1.4E-34 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS03670 deaebe0460e4ebb4b39800a2f39c212d 221 Gene3D G3DSA:3.40.50.1240 3 212 3.7E-76 T 11-11-2016 IPR029033 Histidine phosphatase superfamily TW_RS03670 deaebe0460e4ebb4b39800a2f39c212d 221 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 209 3.0E-89 T 11-11-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 TW_RS03670 deaebe0460e4ebb4b39800a2f39c212d 221 SMART SM00855 3 180 1.3E-23 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 TW_RS03670 deaebe0460e4ebb4b39800a2f39c212d 221 SUPERFAMILY SSF53254 3 212 2.21E-64 T 11-11-2016 IPR029033 Histidine phosphatase superfamily TW_RS03670 deaebe0460e4ebb4b39800a2f39c212d 221 PIRSF PIRSF000709 3 219 6.7E-8 T 11-11-2016 TW_RS03670 deaebe0460e4ebb4b39800a2f39c212d 221 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 220 41.64 T 11-11-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 TW_RS03670 deaebe0460e4ebb4b39800a2f39c212d 221 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 199 1.7E-31 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 TW_RS03055 4c04d0a58066b18652132b9063d8445f 1556 Pfam PF07861 WisP family N-Terminal Region 48 286 4.5E-156 T 11-11-2016 IPR012503 WisP, N-terminal TW_RS03055 4c04d0a58066b18652132b9063d8445f 1556 Pfam PF05345 Putative Ig domain 776 827 4.7E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS03055 4c04d0a58066b18652132b9063d8445f 1556 Pfam PF05345 Putative Ig domain 990 1041 1.1E-8 T 11-11-2016 IPR008009 Putative Ig TW_RS03055 4c04d0a58066b18652132b9063d8445f 1556 Pfam PF05345 Putative Ig domain 1489 1538 3.9E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS03055 4c04d0a58066b18652132b9063d8445f 1556 Pfam PF05345 Putative Ig domain 1400 1449 3.9E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS03055 4c04d0a58066b18652132b9063d8445f 1556 Pfam PF05345 Putative Ig domain 883 936 2.5E-9 T 11-11-2016 IPR008009 Putative Ig TW_RS03055 4c04d0a58066b18652132b9063d8445f 1556 Pfam PF05345 Putative Ig domain 1222 1271 3.9E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS03055 4c04d0a58066b18652132b9063d8445f 1556 Pfam PF05345 Putative Ig domain 676 726 2.3E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS03055 4c04d0a58066b18652132b9063d8445f 1556 Pfam PF05345 Putative Ig domain 1311 1360 3.9E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS00500 04d6350e2fac9f6fbeadebf009b20555 254 SUPERFAMILY SSF81606 22 252 9.81E-52 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TW_RS00500 04d6350e2fac9f6fbeadebf009b20555 254 Pfam PF13672 Protein phosphatase 2C 34 214 4.4E-9 T 11-11-2016 TW_RS00500 04d6350e2fac9f6fbeadebf009b20555 254 SMART SM00331 13 251 3.1E-14 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TW_RS00500 04d6350e2fac9f6fbeadebf009b20555 254 Gene3D G3DSA:3.60.40.10 21 251 2.1E-55 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TW_RS00500 04d6350e2fac9f6fbeadebf009b20555 254 SMART SM00332 7 249 2.6E-22 T 11-11-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 Gene3D G3DSA:3.40.50.1440 14 214 1.6E-89 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.5E-50 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.5E-50 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.5E-50 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.5E-50 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 SUPERFAMILY SSF52490 12 208 2.62E-65 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 SUPERFAMILY SSF55307 204 317 1.1E-41 T 11-11-2016 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 Pfam PF12327 FtsZ family, C-terminal domain 222 316 6.4E-33 T 11-11-2016 IPR024757 Cell division protein FtsZ, C-terminal TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 3.1E-37 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 9 317 7.6E-123 T 11-11-2016 IPR000158 Cell division protein FtsZ GO:0005525 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 11-11-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 SMART SM00864 13 205 1.1E-105 T 11-11-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 SMART SM00865 207 324 7.7E-52 T 11-11-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 353 37.773 T 11-11-2016 IPR000158 Cell division protein FtsZ GO:0005525 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 Gene3D G3DSA:3.30.1330.20 215 317 2.7E-46 T 11-11-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-983189 TW_RS01335 3d8b38e10dd34db01f9d880b702c1656 361 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 11-11-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TW_RS03620 deda585d0d58d0a5c0fb2ccaeac6989d 439 Gene3D G3DSA:1.20.1250.20 229 429 1.5E-29 T 11-11-2016 TW_RS03620 deda585d0d58d0a5c0fb2ccaeac6989d 439 SUPERFAMILY SSF103473 6 422 1.27E-74 T 11-11-2016 IPR020846 Major facilitator superfamily domain TW_RS03620 deda585d0d58d0a5c0fb2ccaeac6989d 439 Gene3D G3DSA:1.20.1250.20 8 203 6.2E-33 T 11-11-2016 TW_RS03620 deda585d0d58d0a5c0fb2ccaeac6989d 439 Pfam PF07690 Major Facilitator Superfamily 16 385 7.8E-53 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TW_RS03620 deda585d0d58d0a5c0fb2ccaeac6989d 439 PIRSF PIRSF002808 1 438 4.1E-36 T 11-11-2016 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 TW_RS01200 89daeec0dbf80f3b1ab5a90b3815e852 183 Pfam PF00673 ribosomal L5P family C-terminus 89 181 2.5E-36 T 11-11-2016 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01200 89daeec0dbf80f3b1ab5a90b3815e852 183 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 5 183 41.238 T 11-11-2016 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01200 89daeec0dbf80f3b1ab5a90b3815e852 183 Pfam PF00281 Ribosomal protein L5 28 84 2.5E-23 T 11-11-2016 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01200 89daeec0dbf80f3b1ab5a90b3815e852 183 Gene3D G3DSA:3.30.1440.10 6 183 2.0E-67 T 11-11-2016 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01200 89daeec0dbf80f3b1ab5a90b3815e852 183 SUPERFAMILY SSF55282 7 183 2.59E-67 T 11-11-2016 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01200 89daeec0dbf80f3b1ab5a90b3815e852 183 PIRSF PIRSF002161 3 183 4.1E-56 T 11-11-2016 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS02770 9554b46d0ea7d1156d0b7752b62790ae 526 Gene3D G3DSA:1.20.810.10 16 436 2.5E-88 T 11-11-2016 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 TW_RS02770 9554b46d0ea7d1156d0b7752b62790ae 526 SUPERFAMILY SSF81342 16 294 5.81E-63 T 11-11-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 TW_RS02770 9554b46d0ea7d1156d0b7752b62790ae 526 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 115 288 1.7E-60 T 11-11-2016 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 TW_RS01290 c222c1c187e1348fe680b2ea103a5ddf 415 SUPERFAMILY SSF158791 163 262 4.32E-23 T 11-11-2016 TW_RS01290 c222c1c187e1348fe680b2ea103a5ddf 415 Pfam PF00571 CBS domain 268 329 7.4E-5 T 11-11-2016 IPR000644 CBS domain TW_RS01290 c222c1c187e1348fe680b2ea103a5ddf 415 Pfam PF00571 CBS domain 339 391 1.0E-6 T 11-11-2016 IPR000644 CBS domain TW_RS01290 c222c1c187e1348fe680b2ea103a5ddf 415 SUPERFAMILY SSF54631 266 393 3.28E-24 T 11-11-2016 TW_RS01290 c222c1c187e1348fe680b2ea103a5ddf 415 Gene3D G3DSA:1.25.60.10 163 261 1.3E-25 T 11-11-2016 TW_RS01290 c222c1c187e1348fe680b2ea103a5ddf 415 SMART SM00116 343 391 1.7E-4 T 11-11-2016 IPR000644 CBS domain TW_RS01290 c222c1c187e1348fe680b2ea103a5ddf 415 SMART SM00116 274 332 9.2 T 11-11-2016 IPR000644 CBS domain TW_RS01290 c222c1c187e1348fe680b2ea103a5ddf 415 Gene3D G3DSA:3.10.580.10 266 391 8.9E-21 T 11-11-2016 TW_RS01290 c222c1c187e1348fe680b2ea103a5ddf 415 Pfam PF03448 MgtE intracellular N domain 166 264 2.7E-23 T 11-11-2016 IPR006668 Magnesium transporter, MgtE intracellular domain TW_RS01290 c222c1c187e1348fe680b2ea103a5ddf 415 SMART SM00924 164 267 2.6E-28 T 11-11-2016 IPR006668 Magnesium transporter, MgtE intracellular domain TW_RS01380 9585de715d7d1f125e1061e77a67cac5 241 Gene3D G3DSA:3.40.1130.10 17 179 2.6E-17 T 11-11-2016 TW_RS01380 9585de715d7d1f125e1061e77a67cac5 241 SMART SM00563 39 166 4.8E-25 T 11-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TW_RS01380 9585de715d7d1f125e1061e77a67cac5 241 Pfam PF01553 Acyltransferase 31 159 1.5E-21 T 11-11-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 TW_RS01380 9585de715d7d1f125e1061e77a67cac5 241 SUPERFAMILY SSF69593 4 223 1.96E-45 T 11-11-2016 TW_RS04130 cc66f13a26d88751b45f0f5cc6cc0cec 287 SMART SM00271 9 67 4.3E-25 T 11-11-2016 IPR001623 DnaJ domain TW_RS04130 cc66f13a26d88751b45f0f5cc6cc0cec 287 Gene3D G3DSA:2.60.260.20 98 174 9.2E-17 T 11-11-2016 TW_RS04130 cc66f13a26d88751b45f0f5cc6cc0cec 287 SUPERFAMILY SSF49493 101 186 1.57E-20 T 11-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TW_RS04130 cc66f13a26d88751b45f0f5cc6cc0cec 287 PRINTS PR00625 DnaJ domain signature 47 67 9.8E-18 T 11-11-2016 IPR001623 DnaJ domain TW_RS04130 cc66f13a26d88751b45f0f5cc6cc0cec 287 PRINTS PR00625 DnaJ domain signature 12 30 9.8E-18 T 11-11-2016 IPR001623 DnaJ domain TW_RS04130 cc66f13a26d88751b45f0f5cc6cc0cec 287 PRINTS PR00625 DnaJ domain signature 30 45 9.8E-18 T 11-11-2016 IPR001623 DnaJ domain TW_RS04130 cc66f13a26d88751b45f0f5cc6cc0cec 287 SUPERFAMILY SSF49493 178 256 2.09E-19 T 11-11-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TW_RS04130 cc66f13a26d88751b45f0f5cc6cc0cec 287 Pfam PF00226 DnaJ domain 10 72 2.2E-24 T 11-11-2016 IPR001623 DnaJ domain TW_RS04130 cc66f13a26d88751b45f0f5cc6cc0cec 287 Pfam PF01556 DnaJ C terminal domain 109 252 2.4E-30 T 11-11-2016 IPR002939 Chaperone DnaJ, C-terminal TW_RS04130 cc66f13a26d88751b45f0f5cc6cc0cec 287 Gene3D G3DSA:2.60.260.20 176 253 1.9E-20 T 11-11-2016 TW_RS04130 cc66f13a26d88751b45f0f5cc6cc0cec 287 SUPERFAMILY SSF46565 9 98 2.09E-26 T 11-11-2016 IPR001623 DnaJ domain TW_RS04130 cc66f13a26d88751b45f0f5cc6cc0cec 287 Gene3D G3DSA:1.10.287.110 3 96 1.3E-29 T 11-11-2016 IPR001623 DnaJ domain TW_RS02440 f993efb34856e083401011dbe2dd7c25 83 SUPERFAMILY SSF143800 2 79 3.77E-20 T 11-11-2016 TW_RS02440 f993efb34856e083401011dbe2dd7c25 83 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 80 6.3E-18 T 11-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02440 f993efb34856e083401011dbe2dd7c25 83 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 11-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02440 f993efb34856e083401011dbe2dd7c25 83 Pfam PF01197 Ribosomal protein L31 2 79 1.7E-25 T 11-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02440 f993efb34856e083401011dbe2dd7c25 83 PRINTS PR01249 Ribosomal protein L31 signature 45 60 4.4E-17 T 11-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02440 f993efb34856e083401011dbe2dd7c25 83 PRINTS PR01249 Ribosomal protein L31 signature 60 78 4.4E-17 T 11-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02440 f993efb34856e083401011dbe2dd7c25 83 PRINTS PR01249 Ribosomal protein L31 signature 2 19 4.4E-17 T 11-11-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02440 f993efb34856e083401011dbe2dd7c25 83 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 23.667 T 11-11-2016 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01345 2e18076ee2d9e17264b61c8707d4e509 175 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 38 5.4E-14 T 11-11-2016 IPR019933 DivIVA domain TW_RS01345 2e18076ee2d9e17264b61c8707d4e509 175 Gene3D G3DSA:1.20.5.620 84 119 7.4E-4 T 11-11-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain TW_RS01345 2e18076ee2d9e17264b61c8707d4e509 175 Pfam PF05103 DivIVA protein 3 131 2.4E-13 T 11-11-2016 IPR007793 DivIVA family TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 PIRSF PIRSF000149 1 336 4.8E-122 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 3.2E-38 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 3.2E-38 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 3.2E-38 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 3.2E-38 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 3.2E-38 T 11-11-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 SMART SM00846 3 155 2.3E-80 T 11-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 11-11-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 Gene3D G3DSA:3.30.360.10 164 317 2.5E-67 T 11-11-2016 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 327 2.1E-123 T 11-11-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 315 2.6E-59 T 11-11-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 155 1.1E-53 T 11-11-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 Gene3D G3DSA:3.40.50.720 2 163 1.1E-66 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 SUPERFAMILY SSF55347 155 316 1.71E-65 T 11-11-2016 TW_RS02505 be5cb7ea412d60137b955fc49c648595 337 SUPERFAMILY SSF51735 2 182 8.18E-56 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS03315 c27a652bb2a5fb4a4e41302d46da4f70 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 15.121 T 11-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TW_RS03315 c27a652bb2a5fb4a4e41302d46da4f70 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 2.4E-12 T 11-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TW_RS03315 c27a652bb2a5fb4a4e41302d46da4f70 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 2.4E-12 T 11-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TW_RS03315 c27a652bb2a5fb4a4e41302d46da4f70 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 2.4E-12 T 11-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TW_RS03315 c27a652bb2a5fb4a4e41302d46da4f70 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 4.8E-20 T 11-11-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TW_RS03315 c27a652bb2a5fb4a4e41302d46da4f70 64 SUPERFAMILY SSF143034 2 63 1.57E-19 T 11-11-2016 TW_RS03315 c27a652bb2a5fb4a4e41302d46da4f70 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 11-11-2016 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03315 c27a652bb2a5fb4a4e41302d46da4f70 64 Pfam PF01632 Ribosomal protein L35 2 62 1.2E-21 T 11-11-2016 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 SUPERFAMILY SSF49313 1196 1261 4.71E-6 T 11-11-2016 IPR015919 Cadherin-like GO:0005509|GO:0016020 TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF07860 WisP family C-Terminal Region 2059 2117 3.4E-36 T 11-11-2016 IPR012421 WisP, C-terminal TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 1889 1944 1.4E-5 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 1619 1669 1.6E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 641 708 9.6E-12 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 1303 1356 1.4E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 537 590 2.0E-11 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 1408 1472 2.5E-8 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 1196 1247 1.0E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 306 365 2.7E-12 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 1998 2042 1.6E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 1524 1575 1.4E-9 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 979 1037 3.3E-14 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 1105 1144 3.7E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 852 916 2.2E-14 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Pfam PF05345 Putative Ig domain 1717 1763 4.7E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Gene3D G3DSA:2.60.40.10 1172 1259 7.9E-6 T 11-11-2016 IPR013783 Immunoglobulin-like fold TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Gene3D G3DSA:2.60.40.10 507 607 1.8E-6 T 11-11-2016 IPR013783 Immunoglobulin-like fold TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 Gene3D G3DSA:2.60.40.10 279 361 5.0E-5 T 11-11-2016 IPR013783 Immunoglobulin-like fold TW_RS04205 e4984649dcfdabb1391d72bb38ab9035 2136 SUPERFAMILY SSF49313 517 606 3.61E-7 T 11-11-2016 IPR015919 Cadherin-like GO:0005509|GO:0016020 TW_RS03955 3b06b1a2fd236dbf4c6627a28abe6e08 205 SMART SM00738 22 130 2.6E-30 T 11-11-2016 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TW_RS03955 3b06b1a2fd236dbf4c6627a28abe6e08 205 PRINTS PR00338 Transcription termination factor NUSG signature 180 196 1.4E-13 T 11-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 TW_RS03955 3b06b1a2fd236dbf4c6627a28abe6e08 205 PRINTS PR00338 Transcription termination factor NUSG signature 162 177 1.4E-13 T 11-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 TW_RS03955 3b06b1a2fd236dbf4c6627a28abe6e08 205 PRINTS PR00338 Transcription termination factor NUSG signature 77 89 1.4E-13 T 11-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 TW_RS03955 3b06b1a2fd236dbf4c6627a28abe6e08 205 SMART SM00739 150 177 8.1E-4 T 11-11-2016 IPR005824 KOW TW_RS03955 3b06b1a2fd236dbf4c6627a28abe6e08 205 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 22 204 20.083 T 11-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 TW_RS03955 3b06b1a2fd236dbf4c6627a28abe6e08 205 Gene3D G3DSA:3.30.70.940 24 129 1.3E-34 T 11-11-2016 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TW_RS03955 3b06b1a2fd236dbf4c6627a28abe6e08 205 SUPERFAMILY SSF50104 148 203 2.23E-15 T 11-11-2016 IPR008991 Translation protein SH3-like domain TW_RS03955 3b06b1a2fd236dbf4c6627a28abe6e08 205 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 25 203 1.3E-49 T 11-11-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 TW_RS03955 3b06b1a2fd236dbf4c6627a28abe6e08 205 Gene3D G3DSA:2.30.30.30 147 203 1.1E-23 T 11-11-2016 IPR014722 Ribosomal protein L2 domain 2 TW_RS03955 3b06b1a2fd236dbf4c6627a28abe6e08 205 Pfam PF02357 Transcription termination factor nusG 24 126 9.1E-22 T 11-11-2016 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TW_RS03955 3b06b1a2fd236dbf4c6627a28abe6e08 205 SUPERFAMILY SSF82679 24 128 6.41E-31 T 11-11-2016 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TW_RS03650 41e344a8ccf151faad6814b3d553ba46 186 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 3 171 30.256 T 11-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TW_RS03650 41e344a8ccf151faad6814b3d553ba46 186 Pfam PF01195 Peptidyl-tRNA hydrolase 5 166 2.5E-48 T 11-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TW_RS03650 41e344a8ccf151faad6814b3d553ba46 186 Gene3D G3DSA:3.40.50.1470 3 174 1.2E-54 T 11-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TW_RS03650 41e344a8ccf151faad6814b3d553ba46 186 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 5 168 1.6E-47 T 11-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TW_RS03650 41e344a8ccf151faad6814b3d553ba46 186 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 16 29 - T 11-11-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 TW_RS03650 41e344a8ccf151faad6814b3d553ba46 186 SUPERFAMILY SSF53178 3 176 4.32E-54 T 11-11-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TW_RS03640 59f3cf2c9eb61b17a6a1277e44cb4183 226 SMART SM00934 13 217 5.1E-18 T 11-11-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS03640 59f3cf2c9eb61b17a6a1277e44cb4183 226 Gene3D G3DSA:3.20.20.70 10 225 5.0E-59 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS03640 59f3cf2c9eb61b17a6a1277e44cb4183 226 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 13 215 1.1E-13 T 11-11-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS03640 59f3cf2c9eb61b17a6a1277e44cb4183 226 SUPERFAMILY SSF51366 10 225 2.07E-31 T 11-11-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 TW_RS04465 430fdc55af904ab63d0825c6ff9db30d 196 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 17 102 9.0E-44 T 11-11-2016 IPR000238 Ribosome-binding factor A GO:0006364 TW_RS04465 430fdc55af904ab63d0825c6ff9db30d 196 SUPERFAMILY SSF89919 9 118 7.46E-22 T 11-11-2016 IPR023799 Ribosome-binding factor A domain TW_RS04465 430fdc55af904ab63d0825c6ff9db30d 196 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 10 122 15.628 T 11-11-2016 IPR000238 Ribosome-binding factor A GO:0006364 TW_RS04465 430fdc55af904ab63d0825c6ff9db30d 196 Pfam PF02033 Ribosome-binding factor A 14 115 6.1E-20 T 11-11-2016 IPR000238 Ribosome-binding factor A GO:0006364 TW_RS04465 430fdc55af904ab63d0825c6ff9db30d 196 Gene3D G3DSA:3.30.300.20 11 123 3.8E-24 T 11-11-2016 IPR015946 K homology domain-like, alpha/beta TW_RS04465 430fdc55af904ab63d0825c6ff9db30d 196 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 9 117 2.2E-17 T 11-11-2016 IPR000238 Ribosome-binding factor A GO:0006364 TW_RS02215 8dace8315bd16868af1fc13fb7d2d2fd 299 Gene3D G3DSA:1.10.3720.10 59 291 1.1E-28 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TW_RS02215 8dace8315bd16868af1fc13fb7d2d2fd 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 289 1.3E-16 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TW_RS02215 8dace8315bd16868af1fc13fb7d2d2fd 299 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 5 291 1.8E-66 T 11-11-2016 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 TW_RS02215 8dace8315bd16868af1fc13fb7d2d2fd 299 SUPERFAMILY SSF161098 50 285 2.35E-24 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TW_RS03060 9b0d72b018a07658d5ca267308db77c4 211 ProSitePatterns PS01317 SsrA-binding protein. 45 57 - T 11-11-2016 IPR020081 SsrA-binding protein, conserved site TW_RS03060 9b0d72b018a07658d5ca267308db77c4 211 Gene3D G3DSA:2.40.280.10 26 145 6.3E-42 T 11-11-2016 IPR023620 Small protein B TW_RS03060 9b0d72b018a07658d5ca267308db77c4 211 SUPERFAMILY SSF74982 23 150 1.83E-44 T 11-11-2016 IPR023620 Small protein B TW_RS03060 9b0d72b018a07658d5ca267308db77c4 211 Pfam PF01668 SmpB protein 26 89 5.1E-24 T 11-11-2016 IPR000037 SsrA-binding protein GO:0003723 TW_RS03060 9b0d72b018a07658d5ca267308db77c4 211 TIGRFAM TIGR00086 smpB: SsrA-binding protein 26 168 1.0E-54 T 11-11-2016 IPR000037 SsrA-binding protein GO:0003723 TW_RS03060 9b0d72b018a07658d5ca267308db77c4 211 Hamap MF_00023 SsrA-binding protein [smpB]. 1 173 54.217 T 11-11-2016 IPR000037 SsrA-binding protein GO:0003723 TW_RS03060 9b0d72b018a07658d5ca267308db77c4 211 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 27 150 1.0E-67 T 11-11-2016 IPR000037 SsrA-binding protein GO:0003723 TW_RS00305 e75bcd66c818cabf1d9545c632faba7d 323 Gene3D G3DSA:3.40.50.1980 53 167 1.5E-24 T 11-11-2016 TW_RS00305 e75bcd66c818cabf1d9545c632faba7d 323 Gene3D G3DSA:3.40.50.1980 168 313 5.8E-14 T 11-11-2016 TW_RS00305 e75bcd66c818cabf1d9545c632faba7d 323 Pfam PF01497 Periplasmic binding protein 54 289 2.0E-19 T 11-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 TW_RS00305 e75bcd66c818cabf1d9545c632faba7d 323 SUPERFAMILY SSF53807 53 312 3.6E-41 T 11-11-2016 TW_RS02585 ece2adbcbc3211c8465f99d91166cebc 479 Gene3D G3DSA:1.10.3210.10 28 243 3.4E-58 T 11-11-2016 IPR006674 HD domain TW_RS02585 ece2adbcbc3211c8465f99d91166cebc 479 Pfam PF13286 Phosphohydrolase-associated domain 365 457 2.0E-13 T 11-11-2016 IPR026875 Phosphohydrolase-associated domain TW_RS02585 ece2adbcbc3211c8465f99d91166cebc 479 Gene3D G3DSA:1.10.3410.10 244 293 1.7E-12 T 11-11-2016 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain TW_RS02585 ece2adbcbc3211c8465f99d91166cebc 479 Gene3D G3DSA:1.10.3410.10 327 382 1.7E-12 T 11-11-2016 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain TW_RS02585 ece2adbcbc3211c8465f99d91166cebc 479 SUPERFAMILY SSF109604 29 180 3.14E-49 T 11-11-2016 TW_RS02585 ece2adbcbc3211c8465f99d91166cebc 479 SUPERFAMILY SSF109604 225 259 3.14E-49 T 11-11-2016 TW_RS02585 ece2adbcbc3211c8465f99d91166cebc 479 Pfam PF01966 HD domain 79 246 1.5E-14 T 11-11-2016 IPR006674 HD domain TW_RS02585 ece2adbcbc3211c8465f99d91166cebc 479 SMART SM00471 75 257 1.8E-9 T 11-11-2016 IPR003607 HD/PDEase domain TW_RS02585 ece2adbcbc3211c8465f99d91166cebc 479 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 41 459 6.8E-73 T 11-11-2016 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 TW_RS02940 39198fca009de0df095878e26d88cee0 601 SMART SM00740 536 601 5.5E-8 T 11-11-2016 IPR005543 PASTA domain TW_RS02940 39198fca009de0df095878e26d88cee0 601 SMART SM00740 399 462 23.0 T 11-11-2016 IPR005543 PASTA domain TW_RS02940 39198fca009de0df095878e26d88cee0 601 SMART SM00740 469 535 1.7E-14 T 11-11-2016 IPR005543 PASTA domain TW_RS02940 39198fca009de0df095878e26d88cee0 601 SMART SM00740 333 398 0.027 T 11-11-2016 IPR005543 PASTA domain TW_RS02940 39198fca009de0df095878e26d88cee0 601 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 11-11-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TW_RS02940 39198fca009de0df095878e26d88cee0 601 SUPERFAMILY SSF56112 12 273 1.62E-75 T 11-11-2016 IPR011009 Protein kinase-like domain TW_RS02940 39198fca009de0df095878e26d88cee0 601 Pfam PF03793 PASTA domain 475 535 3.4E-14 T 11-11-2016 IPR005543 PASTA domain TW_RS02940 39198fca009de0df095878e26d88cee0 601 Pfam PF03793 PASTA domain 337 397 9.2E-8 T 11-11-2016 IPR005543 PASTA domain TW_RS02940 39198fca009de0df095878e26d88cee0 601 Pfam PF03793 PASTA domain 540 599 1.0E-9 T 11-11-2016 IPR005543 PASTA domain TW_RS02940 39198fca009de0df095878e26d88cee0 601 Pfam PF00069 Protein kinase domain 18 266 5.8E-52 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TW_RS02940 39198fca009de0df095878e26d88cee0 601 Gene3D G3DSA:1.10.510.10 84 269 8.0E-54 T 11-11-2016 TW_RS02940 39198fca009de0df095878e26d88cee0 601 Gene3D G3DSA:3.30.200.20 8 83 2.9E-20 T 11-11-2016 TW_RS02940 39198fca009de0df095878e26d88cee0 601 SMART SM00220 16 272 1.2E-59 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TW_RS00885 b77f13d3221f6e50f2ce64c0c0940231 364 SUPERFAMILY SSF47240 8 76 3.95E-6 T 11-11-2016 IPR009078 Ferritin-like superfamily TW_RS00885 b77f13d3221f6e50f2ce64c0c0940231 364 Gene3D G3DSA:1.20.1260.10 16 70 2.3E-7 T 11-11-2016 IPR012347 Ferritin-related TW_RS00885 b77f13d3221f6e50f2ce64c0c0940231 364 Pfam PF01988 VIT family 130 357 1.5E-61 T 11-11-2016 IPR008217 Ccc1 family TW_RS00260 71289754180d32eebe1d22fd0e4c136a 125 SMART SM00357 3 65 5.4E-5 T 11-11-2016 IPR011129 Cold shock protein GO:0003676 TW_RS00260 71289754180d32eebe1d22fd0e4c136a 125 PRINTS PR00050 Cold shock protein signature 4 19 1.2E-5 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TW_RS00260 71289754180d32eebe1d22fd0e4c136a 125 PRINTS PR00050 Cold shock protein signature 38 56 1.2E-5 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TW_RS00260 71289754180d32eebe1d22fd0e4c136a 125 PRINTS PR00050 Cold shock protein signature 24 33 1.2E-5 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TW_RS00260 71289754180d32eebe1d22fd0e4c136a 125 Gene3D G3DSA:2.40.50.140 2 66 3.0E-13 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS00260 71289754180d32eebe1d22fd0e4c136a 125 Pfam PF00313 'Cold-shock' DNA-binding domain 4 58 3.6E-7 T 11-11-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TW_RS00260 71289754180d32eebe1d22fd0e4c136a 125 SUPERFAMILY SSF50249 1 64 2.69E-11 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS02495 4fc6980e78521daede972269428d633d 293 ProSitePatterns PS00171 Triosephosphate isomerase active site. 216 226 - T 11-11-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02495 4fc6980e78521daede972269428d633d 293 Gene3D G3DSA:3.20.20.70 18 290 6.2E-68 T 11-11-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 TW_RS02495 4fc6980e78521daede972269428d633d 293 Pfam PF00121 Triosephosphate isomerase 20 288 2.4E-45 T 11-11-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02495 4fc6980e78521daede972269428d633d 293 SUPERFAMILY SSF51351 19 290 1.26E-53 T 11-11-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS02495 4fc6980e78521daede972269428d633d 293 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 18 291 30.448 T 11-11-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS04350 3106f0652fe5e2a2d965a5adb876ecc5 481 Pfam PF08328 Adenylosuccinate lyase C-terminal 328 448 3.4E-44 T 11-11-2016 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 TW_RS04350 3106f0652fe5e2a2d965a5adb876ecc5 481 SUPERFAMILY SSF48557 10 456 6.6E-90 T 11-11-2016 IPR008948 L-Aspartase-like GO:0003824 TW_RS04350 3106f0652fe5e2a2d965a5adb876ecc5 481 Pfam PF00206 Lyase 14 308 1.9E-45 T 11-11-2016 IPR022761 Fumarate lyase, N-terminal TW_RS04350 3106f0652fe5e2a2d965a5adb876ecc5 481 Gene3D G3DSA:1.20.200.10 117 384 4.7E-76 T 11-11-2016 TW_RS04350 3106f0652fe5e2a2d965a5adb876ecc5 481 Gene3D G3DSA:1.10.275.10 7 116 2.5E-28 T 11-11-2016 IPR024083 Fumarase/histidase, N-terminal TW_RS04350 3106f0652fe5e2a2d965a5adb876ecc5 481 Gene3D G3DSA:1.10.40.30 385 448 7.0E-24 T 11-11-2016 TW_RS04350 3106f0652fe5e2a2d965a5adb876ecc5 481 PRINTS PR00149 Fumarate lyase superfamily signature 248 275 3.8E-14 T 11-11-2016 IPR000362 Fumarate lyase family TW_RS04350 3106f0652fe5e2a2d965a5adb876ecc5 481 PRINTS PR00149 Fumarate lyase superfamily signature 160 178 3.8E-14 T 11-11-2016 IPR000362 Fumarate lyase family TW_RS04350 3106f0652fe5e2a2d965a5adb876ecc5 481 PRINTS PR00149 Fumarate lyase superfamily signature 291 307 3.8E-14 T 11-11-2016 IPR000362 Fumarate lyase family TW_RS04350 3106f0652fe5e2a2d965a5adb876ecc5 481 PRINTS PR00149 Fumarate lyase superfamily signature 114 132 3.8E-14 T 11-11-2016 IPR000362 Fumarate lyase family TW_RS04350 3106f0652fe5e2a2d965a5adb876ecc5 481 ProSitePatterns PS00163 Fumarate lyases signature. 291 300 - T 11-11-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 TW_RS01790 3ce545e58f8910106e256c59ea9463f9 366 Pfam PF00953 Glycosyl transferase family 4 83 239 2.1E-33 T 11-11-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TW_RS01790 3ce545e58f8910106e256c59ea9463f9 366 ProSitePatterns PS01348 MraY family signature 2. 152 163 - T 11-11-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TW_RS02645 d11c62c76edf87d204a768aa83365fa7 210 SUPERFAMILY SSF49299 109 164 9.16E-7 T 11-11-2016 IPR000601 PKD domain TW_RS02645 d11c62c76edf87d204a768aa83365fa7 210 Gene3D G3DSA:2.60.40.670 120 167 5.3E-6 T 11-11-2016 IPR000601 PKD domain TW_RS00690 2453f22476ca8b68f3dfc25f4081d4e0 627 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 392 626 8.2E-16 T 11-11-2016 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 TW_RS00690 2453f22476ca8b68f3dfc25f4081d4e0 627 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 172 249 1.0E-6 T 11-11-2016 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 TW_RS03560 010a965ac620eece01fb162d1da584f6 432 SUPERFAMILY SSF53383 24 429 2.19E-119 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase TW_RS03560 010a965ac620eece01fb162d1da584f6 432 Pfam PF00202 Aminotransferase class-III 28 427 8.0E-113 T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TW_RS03560 010a965ac620eece01fb162d1da584f6 432 Gene3D G3DSA:3.40.640.10 70 315 7.0E-74 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TW_RS03560 010a965ac620eece01fb162d1da584f6 432 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 248 285 - T 11-11-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TW_RS03560 010a965ac620eece01fb162d1da584f6 432 Gene3D G3DSA:3.90.1150.10 316 431 5.2E-31 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TW_RS00350 41af623204b179a11f61494c0694b28d 545 Gene3D G3DSA:2.30.30.300 195 226 2.0E-12 T 11-11-2016 IPR023386 Lysine-tRNA ligase, insertion domain GO:0004824 KEGG: 00970+6.1.1.6 TW_RS00350 41af623204b179a11f61494c0694b28d 545 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 19 535 2.0E-109 T 11-11-2016 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TW_RS00350 41af623204b179a11f61494c0694b28d 545 Gene3D G3DSA:3.40.50.620 19 194 3.8E-54 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS00350 41af623204b179a11f61494c0694b28d 545 Gene3D G3DSA:3.40.50.620 233 287 3.8E-54 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS00350 41af623204b179a11f61494c0694b28d 545 Gene3D G3DSA:1.10.10.350 448 539 4.8E-17 T 11-11-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TW_RS00350 41af623204b179a11f61494c0694b28d 545 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 45 54 - T 11-11-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TW_RS00350 41af623204b179a11f61494c0694b28d 545 SUPERFAMILY SSF52374 19 333 1.37E-58 T 11-11-2016 TW_RS00350 41af623204b179a11f61494c0694b28d 545 Gene3D G3DSA:3.40.50.620 288 333 2.7E-4 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS00350 41af623204b179a11f61494c0694b28d 545 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 17 543 29.09 T 11-11-2016 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TW_RS00350 41af623204b179a11f61494c0694b28d 545 SUPERFAMILY SSF48163 339 540 5.75E-25 T 11-11-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TW_RS00350 41af623204b179a11f61494c0694b28d 545 Pfam PF01921 tRNA synthetases class I (K) 18 372 3.4E-127 T 11-11-2016 TW_RS02545 351fd77669b7b13398d0236452453c59 356 SMART SM00475 9 269 2.4E-92 T 11-11-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 TW_RS02545 351fd77669b7b13398d0236452453c59 356 SUPERFAMILY SSF47807 179 292 1.5E-25 T 11-11-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 TW_RS02545 351fd77669b7b13398d0236452453c59 356 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 179 269 1.3E-21 T 11-11-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 TW_RS02545 351fd77669b7b13398d0236452453c59 356 SMART SM00279 181 216 1.9E-11 T 11-11-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TW_RS02545 351fd77669b7b13398d0236452453c59 356 Gene3D G3DSA:3.40.50.1010 10 194 5.7E-57 T 11-11-2016 IPR029060 PIN domain-like TW_RS02545 351fd77669b7b13398d0236452453c59 356 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 10 178 4.0E-47 T 11-11-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 TW_RS02545 351fd77669b7b13398d0236452453c59 356 Gene3D G3DSA:1.10.150.20 195 253 1.1E-19 T 11-11-2016 TW_RS02545 351fd77669b7b13398d0236452453c59 356 SUPERFAMILY SSF88723 9 178 1.49E-45 T 11-11-2016 IPR029060 PIN domain-like TW_RS00070 83665ab639c84386845f9949ae83fc40 190 SUPERFAMILY SSF140478 30 177 8.37E-53 T 11-11-2016 IPR023353 LemA-like domain TW_RS00070 83665ab639c84386845f9949ae83fc40 190 Pfam PF04011 LemA family 14 186 1.0E-64 T 11-11-2016 IPR007156 LemA TW_RS00070 83665ab639c84386845f9949ae83fc40 190 Gene3D G3DSA:1.20.1440.20 18 188 2.7E-60 T 11-11-2016 IPR023353 LemA-like domain TW_RS00680 698e392503ebb0b8cb64ed0d869ffb22 698 Pfam PF00271 Helicase conserved C-terminal domain 530 629 6.1E-11 T 11-11-2016 IPR001650 Helicase, C-terminal TW_RS00680 698e392503ebb0b8cb64ed0d869ffb22 698 Gene3D G3DSA:3.40.50.300 219 382 3.1E-14 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00680 698e392503ebb0b8cb64ed0d869ffb22 698 SMART SM00490 546 629 1.2E-10 T 11-11-2016 IPR001650 Helicase, C-terminal TW_RS00680 698e392503ebb0b8cb64ed0d869ffb22 698 Gene3D G3DSA:3.40.50.300 492 632 4.1E-12 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00680 698e392503ebb0b8cb64ed0d869ffb22 698 Pfam PF00176 SNF2 family N-terminal domain 237 445 3.7E-18 T 11-11-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 TW_RS00680 698e392503ebb0b8cb64ed0d869ffb22 698 SUPERFAMILY SSF52540 218 384 6.01E-31 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00680 698e392503ebb0b8cb64ed0d869ffb22 698 SMART SM00487 215 399 2.2E-16 T 11-11-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain TW_RS00680 698e392503ebb0b8cb64ed0d869ffb22 698 SUPERFAMILY SSF52540 324 369 7.51E-36 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00680 698e392503ebb0b8cb64ed0d869ffb22 698 SUPERFAMILY SSF52540 507 671 7.51E-36 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03040 e1fd8a90825e500e22075f0cee845122 150 Pfam PF05345 Putative Ig domain 9 50 1.1E-11 T 11-11-2016 IPR008009 Putative Ig TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 145 219 1.9E-13 T 11-11-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 601 622 - T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 Gene3D G3DSA:3.20.70.20 399 556 2.4E-83 T 11-11-2016 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 Gene3D G3DSA:3.20.70.20 134 344 2.4E-83 T 11-11-2016 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 Gene3D G3DSA:3.20.70.20 716 761 2.4E-83 T 11-11-2016 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 Gene3D G3DSA:3.20.70.20 611 656 2.4E-83 T 11-11-2016 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 148 759 7.0E-203 T 11-11-2016 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 SUPERFAMILY SSF51998 222 660 1.25E-159 T 11-11-2016 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 SUPERFAMILY SSF51998 690 760 1.25E-159 T 11-11-2016 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 433 444 1.2E-39 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 508 530 1.2E-39 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 536 559 1.2E-39 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 611 638 1.2E-39 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 470 493 1.2E-39 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 PRINTS PR01183 Ribonucleotide reductase large chain signature 298 317 1.2E-39 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 Pfam PF02867 Ribonucleotide reductase, barrel domain 223 755 2.6E-168 T 11-11-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 Pfam PF03477 ATP cone domain 4 87 2.4E-10 T 11-11-2016 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TW_RS03795 a410a85745767bce42eb2a2d22a39995 792 SUPERFAMILY SSF48168 8 221 7.85E-48 T 11-11-2016 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TW_RS02775 ad816323d1e459757f06be1467a097b3 327 SUPERFAMILY SSF50022 129 212 4.58E-30 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TW_RS02775 ad816323d1e459757f06be1467a097b3 327 SUPERFAMILY SSF50022 243 325 4.58E-30 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TW_RS02775 ad816323d1e459757f06be1467a097b3 327 Gene3D G3DSA:2.102.10.10 136 325 9.3E-41 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TW_RS02775 ad816323d1e459757f06be1467a097b3 327 Pfam PF00355 Rieske [2Fe-2S] domain 243 299 1.2E-10 T 11-11-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TW_RS02775 ad816323d1e459757f06be1467a097b3 327 PRINTS PR00162 Rieske 2Fe-2S subunit signature 269 281 1.0E-5 T 11-11-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TW_RS02775 ad816323d1e459757f06be1467a097b3 327 PRINTS PR00162 Rieske 2Fe-2S subunit signature 283 295 1.0E-5 T 11-11-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TW_RS02775 ad816323d1e459757f06be1467a097b3 327 PRINTS PR00162 Rieske 2Fe-2S subunit signature 247 258 1.0E-5 T 11-11-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TW_RS03975 04633fa363126505def5c8b040b60418 351 Gene3D G3DSA:3.90.78.10 242 350 6.6E-32 T 11-11-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS03975 04633fa363126505def5c8b040b60418 351 Gene3D G3DSA:3.30.43.10 3 65 2.3E-9 T 11-11-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 TW_RS03975 04633fa363126505def5c8b040b60418 351 SUPERFAMILY SSF56176 5 192 4.09E-32 T 11-11-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 TW_RS03975 04633fa363126505def5c8b040b60418 351 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 351 58.874 T 11-11-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS03975 04633fa363126505def5c8b040b60418 351 Pfam PF01565 FAD binding domain 38 148 6.7E-19 T 11-11-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TW_RS03975 04633fa363126505def5c8b040b60418 351 SUPERFAMILY SSF56194 205 349 2.75E-27 T 11-11-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS03975 04633fa363126505def5c8b040b60418 351 Gene3D G3DSA:3.30.465.10 74 185 6.7E-33 T 11-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 TW_RS03975 04633fa363126505def5c8b040b60418 351 Gene3D G3DSA:3.30.465.10 223 241 6.7E-33 T 11-11-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 TW_RS03975 04633fa363126505def5c8b040b60418 351 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 205 347 1.2E-26 T 11-11-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS01900 0121e9bfbc1a305aa2c4ed8fc6feec28 318 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 113 308 6.2E-13 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS01900 0121e9bfbc1a305aa2c4ed8fc6feec28 318 SUPERFAMILY SSF56219 114 314 1.58E-13 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS02290 ba9e05ea3b32f55f710f8564d63a47cb 551 SUPERFAMILY SSF53697 25 392 4.0E-63 T 11-11-2016 TW_RS02290 ba9e05ea3b32f55f710f8564d63a47cb 551 Gene3D G3DSA:3.40.50.10490 198 294 3.5E-25 T 11-11-2016 TW_RS02290 ba9e05ea3b32f55f710f8564d63a47cb 551 Gene3D G3DSA:3.40.50.10490 460 538 3.3E-11 T 11-11-2016 TW_RS02290 ba9e05ea3b32f55f710f8564d63a47cb 551 Gene3D G3DSA:3.40.50.10490 345 393 5.0E-10 T 11-11-2016 TW_RS02290 ba9e05ea3b32f55f710f8564d63a47cb 551 Gene3D G3DSA:3.40.50.10490 88 197 1.0E-13 T 11-11-2016 TW_RS02710 720ab0f4173cc20157e0a6e11d90430c 269 Gene3D G3DSA:3.20.20.60 20 266 5.5E-90 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TW_RS02710 720ab0f4173cc20157e0a6e11d90430c 269 PIRSF PIRSF000388 1 269 2.5E-103 T 11-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TW_RS02710 720ab0f4173cc20157e0a6e11d90430c 269 SUPERFAMILY SSF51621 16 266 2.2E-81 T 11-11-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 TW_RS02710 720ab0f4173cc20157e0a6e11d90430c 269 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 8 268 35.838 T 11-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TW_RS02710 720ab0f4173cc20157e0a6e11d90430c 269 Pfam PF02548 Ketopantoate hydroxymethyltransferase 17 263 4.9E-90 T 11-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TW_RS02710 720ab0f4173cc20157e0a6e11d90430c 269 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 13 266 2.5E-78 T 11-11-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TW_RS01000 bf128beba5adb22716e49e074844519d 253 SUPERFAMILY SSF52540 13 235 2.96E-45 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01000 bf128beba5adb22716e49e074844519d 253 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS01000 bf128beba5adb22716e49e074844519d 253 Pfam PF00005 ABC transporter 36 173 6.9E-22 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS01000 bf128beba5adb22716e49e074844519d 253 Gene3D G3DSA:3.40.50.300 22 244 1.1E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01000 bf128beba5adb22716e49e074844519d 253 SMART SM00382 44 221 2.0E-6 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS02135 ef28c94f14ce0e890101eab246c2effb 380 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 26 330 4.3E-96 T 11-11-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TW_RS02135 ef28c94f14ce0e890101eab246c2effb 380 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 4 376 33.409 T 11-11-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TW_RS02135 ef28c94f14ce0e890101eab246c2effb 380 SUPERFAMILY SSF56796 21 331 7.07E-82 T 11-11-2016 TW_RS02135 ef28c94f14ce0e890101eab246c2effb 380 Pfam PF01761 3-dehydroquinate synthase 62 327 3.3E-89 T 11-11-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TW_RS02135 ef28c94f14ce0e890101eab246c2effb 380 Gene3D G3DSA:3.40.50.1970 34 167 1.3E-45 T 11-11-2016 TW_RS02135 ef28c94f14ce0e890101eab246c2effb 380 Gene3D G3DSA:1.20.1090.10 168 375 8.8E-59 T 11-11-2016 TW_RS02135 ef28c94f14ce0e890101eab246c2effb 380 PIRSF PIRSF001455 1 378 4.4E-93 T 11-11-2016 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TW_RS02695 38d659eb5b590006a6d7a56a28b90300 178 Pfam PF01230 HIT domain 51 142 2.0E-10 T 11-11-2016 IPR001310 Histidine triad (HIT) protein TW_RS02695 38d659eb5b590006a6d7a56a28b90300 178 SUPERFAMILY SSF54197 16 171 1.86E-39 T 11-11-2016 IPR011146 HIT-like domain GO:0003824 TW_RS02695 38d659eb5b590006a6d7a56a28b90300 178 Gene3D G3DSA:3.30.428.10 38 157 1.3E-31 T 11-11-2016 IPR011146 HIT-like domain GO:0003824 TW_RS01165 df41e6f20e1737e41196f7eb451169fb 119 SUPERFAMILY SSF54843 3 115 1.83E-33 T 11-11-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TW_RS01165 df41e6f20e1737e41196f7eb451169fb 119 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 9 117 24.589 T 11-11-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01165 df41e6f20e1737e41196f7eb451169fb 119 Pfam PF00237 Ribosomal protein L22p/L17e 19 114 5.3E-25 T 11-11-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TW_RS01165 df41e6f20e1737e41196f7eb451169fb 119 ProSitePatterns PS00464 Ribosomal protein L22 signature. 90 114 - T 11-11-2016 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01165 df41e6f20e1737e41196f7eb451169fb 119 Gene3D G3DSA:3.90.470.10 10 117 6.6E-31 T 11-11-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TW_RS01165 df41e6f20e1737e41196f7eb451169fb 119 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 13 113 1.4E-30 T 11-11-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS02875 190536138f53f8524839a2d4414f27b0 356 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 4 141 1.1E-37 T 11-11-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TW_RS02875 190536138f53f8524839a2d4414f27b0 356 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 186 337 7.6E-29 T 11-11-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 TW_RS02875 190536138f53f8524839a2d4414f27b0 356 Gene3D G3DSA:3.40.50.2000 1 197 4.0E-55 T 11-11-2016 TW_RS02875 190536138f53f8524839a2d4414f27b0 356 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 4 354 27.879 T 11-11-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TW_RS02875 190536138f53f8524839a2d4414f27b0 356 SUPERFAMILY SSF53756 3 351 2.3E-88 T 11-11-2016 TW_RS01990 bf59c9c6a895fb6c83a2b530eb94438e 157 PIRSF PIRSF005900 1 157 9.3E-38 T 11-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 TW_RS01990 bf59c9c6a895fb6c83a2b530eb94438e 157 Pfam PF00210 Ferritin-like domain 24 153 2.1E-12 T 11-11-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TW_RS01990 bf59c9c6a895fb6c83a2b530eb94438e 157 ProSitePatterns PS00818 Dps protein family signature 1. 37 53 - T 11-11-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 TW_RS01990 bf59c9c6a895fb6c83a2b530eb94438e 157 Gene3D G3DSA:1.20.1260.10 8 153 5.7E-31 T 11-11-2016 IPR012347 Ferritin-related TW_RS01990 bf59c9c6a895fb6c83a2b530eb94438e 157 SUPERFAMILY SSF47240 3 153 6.84E-33 T 11-11-2016 IPR009078 Ferritin-like superfamily TW_RS01990 bf59c9c6a895fb6c83a2b530eb94438e 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 132 150 1.5E-8 T 11-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 TW_RS01990 bf59c9c6a895fb6c83a2b530eb94438e 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 61 77 1.5E-8 T 11-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 TW_RS01990 bf59c9c6a895fb6c83a2b530eb94438e 157 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 37 53 1.5E-8 T 11-11-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 TW_RS04055 5a7610188d987b73216dbb642d2eb92e 391 ProSitePatterns PS00534 Ferrochelatase signature. 206 226 - T 11-11-2016 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TW_RS04055 5a7610188d987b73216dbb642d2eb92e 391 Gene3D G3DSA:3.40.50.1400 183 328 1.8E-39 T 11-11-2016 TW_RS04055 5a7610188d987b73216dbb642d2eb92e 391 Pfam PF00762 Ferrochelatase 31 348 1.8E-85 T 11-11-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TW_RS04055 5a7610188d987b73216dbb642d2eb92e 391 Gene3D G3DSA:3.40.50.1400 29 182 1.6E-31 T 11-11-2016 TW_RS04055 5a7610188d987b73216dbb642d2eb92e 391 SUPERFAMILY SSF53800 29 382 1.96E-72 T 11-11-2016 TW_RS04055 5a7610188d987b73216dbb642d2eb92e 391 Hamap MF_00323 Ferrochelatase [hemH]. 29 349 26.854 T 11-11-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TW_RS01890 b6869cbaba33321b6276cedc58088e31 524 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 43 506 3.8E-156 T 11-11-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TW_RS01890 b6869cbaba33321b6276cedc58088e31 524 ProSitePatterns PS00571 Amidases signature. 182 213 - T 11-11-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TW_RS01890 b6869cbaba33321b6276cedc58088e31 524 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 41 508 74.68 T 11-11-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TW_RS01890 b6869cbaba33321b6276cedc58088e31 524 Pfam PF01425 Amidase 54 493 6.6E-135 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TW_RS01890 b6869cbaba33321b6276cedc58088e31 524 SUPERFAMILY SSF75304 35 510 8.76E-139 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TW_RS01890 b6869cbaba33321b6276cedc58088e31 524 Gene3D G3DSA:3.90.1300.10 33 509 9.1E-155 T 11-11-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TW_RS02355 d9453fca2a5f0119f8583b40499cc281 511 SMART SM00382 287 486 0.049 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS02355 d9453fca2a5f0119f8583b40499cc281 511 SMART SM00382 26 220 5.4E-7 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS02355 d9453fca2a5f0119f8583b40499cc281 511 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS02355 d9453fca2a5f0119f8583b40499cc281 511 Pfam PF00005 ABC transporter 17 172 4.9E-26 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS02355 d9453fca2a5f0119f8583b40499cc281 511 Pfam PF00005 ABC transporter 279 435 2.1E-19 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS02355 d9453fca2a5f0119f8583b40499cc281 511 SUPERFAMILY SSF52540 2 230 3.82E-50 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02355 d9453fca2a5f0119f8583b40499cc281 511 Gene3D G3DSA:3.40.50.300 273 503 1.2E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02355 d9453fca2a5f0119f8583b40499cc281 511 Gene3D G3DSA:3.40.50.300 1 237 3.3E-55 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02355 d9453fca2a5f0119f8583b40499cc281 511 SUPERFAMILY SSF52540 273 495 7.81E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04395 7b3bf1d4d9b6b63994fbc262c5cb1297 473 Pfam PF01743 Poly A polymerase head domain 34 155 3.1E-29 T 11-11-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TW_RS04395 7b3bf1d4d9b6b63994fbc262c5cb1297 473 Pfam PF01966 HD domain 258 386 1.9E-13 T 11-11-2016 IPR006674 HD domain TW_RS04395 7b3bf1d4d9b6b63994fbc262c5cb1297 473 SUPERFAMILY SSF81301 9 153 8.83E-37 T 11-11-2016 TW_RS04395 7b3bf1d4d9b6b63994fbc262c5cb1297 473 Gene3D G3DSA:3.30.460.10 17 156 2.4E-40 T 11-11-2016 TW_RS04395 7b3bf1d4d9b6b63994fbc262c5cb1297 473 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 5 469 3.1E-233 T 11-11-2016 IPR014065 tRNA adenylyltransferase TW_RS04395 7b3bf1d4d9b6b63994fbc262c5cb1297 473 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 183 244 1.1E-17 T 11-11-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TW_RS04395 7b3bf1d4d9b6b63994fbc262c5cb1297 473 TIGRFAM TIGR00277 HDIG: HDIG domain 255 332 1.7E-15 T 11-11-2016 IPR006675 HDIG domain TW_RS04395 7b3bf1d4d9b6b63994fbc262c5cb1297 473 Gene3D G3DSA:1.10.3090.10 414 436 4.3E-48 T 11-11-2016 TW_RS04395 7b3bf1d4d9b6b63994fbc262c5cb1297 473 Gene3D G3DSA:1.10.3090.10 157 346 4.3E-48 T 11-11-2016 TW_RS04395 7b3bf1d4d9b6b63994fbc262c5cb1297 473 SMART SM00471 254 396 8.8E-8 T 11-11-2016 IPR003607 HD/PDEase domain TW_RS04395 7b3bf1d4d9b6b63994fbc262c5cb1297 473 SUPERFAMILY SSF81891 155 469 7.85E-60 T 11-11-2016 TW_RS01460 2497f2017911400c86d31334b9203e83 476 SUPERFAMILY SSF48179 175 469 1.21E-108 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TW_RS01460 2497f2017911400c86d31334b9203e83 476 Gene3D G3DSA:3.40.50.720 3 178 1.7E-50 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS01460 2497f2017911400c86d31334b9203e83 476 PIRSF PIRSF000109 1 475 3.7E-182 T 11-11-2016 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TW_RS01460 2497f2017911400c86d31334b9203e83 476 SUPERFAMILY SSF51735 3 175 5.04E-46 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS01460 2497f2017911400c86d31334b9203e83 476 Gene3D G3DSA:1.10.1040.10 179 433 8.7E-93 T 11-11-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TW_RS01460 2497f2017911400c86d31334b9203e83 476 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 170 7.3E-46 T 11-11-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 TW_RS01460 2497f2017911400c86d31334b9203e83 476 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 4 468 3.3E-184 T 11-11-2016 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TW_RS01460 2497f2017911400c86d31334b9203e83 476 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 177 467 1.1E-111 T 11-11-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TW_RS01460 2497f2017911400c86d31334b9203e83 476 Gene3D G3DSA:1.20.5.320 436 468 1.7E-17 T 11-11-2016 IPR012284 6-phosphogluconate dehydrogenase, domain 3 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TW_RS01460 2497f2017911400c86d31334b9203e83 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 118 143 1.4E-75 T 11-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TW_RS01460 2497f2017911400c86d31334b9203e83 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 65 94 1.4E-75 T 11-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TW_RS01460 2497f2017911400c86d31334b9203e83 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 3 26 1.4E-75 T 11-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TW_RS01460 2497f2017911400c86d31334b9203e83 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 357 379 1.4E-75 T 11-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TW_RS01460 2497f2017911400c86d31334b9203e83 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 166 194 1.4E-75 T 11-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TW_RS01460 2497f2017911400c86d31334b9203e83 476 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 248 275 1.4E-75 T 11-11-2016 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TW_RS01460 2497f2017911400c86d31334b9203e83 476 SMART SM01350 177 468 6.4E-178 T 11-11-2016 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TW_RS01610 5cbcffdc58ea2d1e2f2e2219306809c5 350 Gene3D G3DSA:3.60.10.10 128 345 3.9E-7 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS01610 5cbcffdc58ea2d1e2f2e2219306809c5 350 SUPERFAMILY SSF56219 128 346 5.1E-21 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS01610 5cbcffdc58ea2d1e2f2e2219306809c5 350 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 135 339 7.8E-13 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS02655 ea410cf31107ed24570a7b01a60d212a 559 Gene3D G3DSA:1.20.1640.10 328 518 3.3E-21 T 11-11-2016 TW_RS02655 ea410cf31107ed24570a7b01a60d212a 559 Pfam PF02355 Protein export membrane protein 343 519 2.1E-13 T 11-11-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TW_RS02655 ea410cf31107ed24570a7b01a60d212a 559 SUPERFAMILY SSF82866 321 518 7.32E-32 T 11-11-2016 TW_RS02655 ea410cf31107ed24570a7b01a60d212a 559 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 44 514 3.5E-94 T 11-11-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 TW_RS02655 ea410cf31107ed24570a7b01a60d212a 559 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 271 507 4.7E-56 T 11-11-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TW_RS02655 ea410cf31107ed24570a7b01a60d212a 559 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 8 530 34.874 T 11-11-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 TW_RS00490 f563ef43e1d31c4eae511d168e979226 374 Pfam PF02163 Peptidase family M50 9 328 8.8E-47 T 11-11-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033 TW_RS00490 f563ef43e1d31c4eae511d168e979226 374 Gene3D G3DSA:2.30.42.10 104 202 5.2E-18 T 11-11-2016 IPR001478 PDZ domain GO:0005515 TW_RS00490 f563ef43e1d31c4eae511d168e979226 374 Pfam PF13180 PDZ domain 140 195 3.2E-7 T 11-11-2016 IPR001478 PDZ domain GO:0005515 TW_RS00490 f563ef43e1d31c4eae511d168e979226 374 SUPERFAMILY SSF50156 98 201 1.71E-15 T 11-11-2016 IPR001478 PDZ domain GO:0005515 TW_RS00490 f563ef43e1d31c4eae511d168e979226 374 SMART SM00228 130 193 2.0E-6 T 11-11-2016 IPR001478 PDZ domain GO:0005515 TW_RS01375 7de2a4784bc86658fabd5ed37b98cc46 441 SUPERFAMILY SSF55205 8 438 2.45E-109 T 11-11-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TW_RS01375 7de2a4784bc86658fabd5ed37b98cc46 441 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 9 437 1.1E-125 T 11-11-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TW_RS01375 7de2a4784bc86658fabd5ed37b98cc46 441 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 432 3.1E-58 T 11-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 TW_RS01375 7de2a4784bc86658fabd5ed37b98cc46 441 Gene3D G3DSA:3.65.10.10 230 437 1.0E-48 T 11-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 TW_RS01375 7de2a4784bc86658fabd5ed37b98cc46 441 Gene3D G3DSA:3.65.10.10 27 229 4.9E-48 T 11-11-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 TW_RS01310 f7aa39980dde5b799c771ee051c29b59 993 Gene3D G3DSA:3.40.50.300 307 386 3.2E-12 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01310 f7aa39980dde5b799c771ee051c29b59 993 Gene3D G3DSA:3.40.50.300 571 657 3.2E-12 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01310 f7aa39980dde5b799c771ee051c29b59 993 SMART SM00382 22 262 2.1E-4 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS01310 f7aa39980dde5b799c771ee051c29b59 993 Pfam PF00580 UvrD/REP helicase N-terminal domain 166 263 5.2E-7 T 11-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TW_RS01310 f7aa39980dde5b799c771ee051c29b59 993 SUPERFAMILY SSF52540 20 421 9.98E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01310 f7aa39980dde5b799c771ee051c29b59 993 SUPERFAMILY SSF52540 452 666 9.98E-46 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01310 f7aa39980dde5b799c771ee051c29b59 993 Gene3D G3DSA:3.40.50.300 17 263 3.4E-20 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01310 f7aa39980dde5b799c771ee051c29b59 993 Pfam PF12705 PD-(D/E)XK nuclease superfamily 743 960 1.9E-22 T 11-11-2016 TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 SUPERFAMILY SSF49313 527 616 3.92E-7 T 11-11-2016 IPR015919 Cadherin-like GO:0005509|GO:0016020 TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 1313 1366 1.6E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 2008 2052 1.7E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 1727 1773 6.3E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 1899 1954 1.5E-5 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 1418 1482 2.7E-8 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 651 718 1.0E-11 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 1206 1257 1.1E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 989 1047 3.6E-14 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 316 375 3.0E-12 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 1629 1679 1.8E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 547 600 2.1E-11 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 1534 1585 1.6E-9 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 1115 1154 4.1E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF05345 Putative Ig domain 862 926 2.4E-14 T 11-11-2016 IPR008009 Putative Ig TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Gene3D G3DSA:2.60.40.10 1182 1269 8.6E-6 T 11-11-2016 IPR013783 Immunoglobulin-like fold TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Gene3D G3DSA:2.60.40.10 289 371 5.5E-5 T 11-11-2016 IPR013783 Immunoglobulin-like fold TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Gene3D G3DSA:2.60.40.10 517 617 2.0E-6 T 11-11-2016 IPR013783 Immunoglobulin-like fold TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 Pfam PF07860 WisP family C-Terminal Region 2069 2197 2.1E-79 T 11-11-2016 IPR012421 WisP, C-terminal TW_RS00605 2390ff1f0d23e883a85e3c934b5ec736 2308 SUPERFAMILY SSF49313 1206 1271 5.18E-6 T 11-11-2016 IPR015919 Cadherin-like GO:0005509|GO:0016020 TW_RS03710 3f443c11ea07af09e9896f03e2d0faf4 269 SMART SM00382 31 217 3.5E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS03710 3f443c11ea07af09e9896f03e2d0faf4 269 Gene3D G3DSA:3.40.50.300 5 255 3.1E-53 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03710 3f443c11ea07af09e9896f03e2d0faf4 269 SUPERFAMILY SSF52540 5 221 3.03E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03710 3f443c11ea07af09e9896f03e2d0faf4 269 Pfam PF00005 ABC transporter 23 170 4.9E-24 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS03710 3f443c11ea07af09e9896f03e2d0faf4 269 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 Pfam PF00958 GMP synthase C terminal domain 419 502 1.2E-31 T 11-11-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 SUPERFAMILY SSF54810 385 503 1.1E-41 T 11-11-2016 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 Gene3D G3DSA:3.30.300.10 381 503 2.5E-44 T 11-11-2016 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 4 185 4.1E-59 T 11-11-2016 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 8.2E-8 T 11-11-2016 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 4 18 8.2E-8 T 11-11-2016 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 8.2E-8 T 11-11-2016 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 Gene3D G3DSA:3.40.50.880 1 205 9.3E-51 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 Pfam PF02540 NAD synthase 200 285 1.1E-5 T 11-11-2016 IPR022310 NAD/GMP synthase TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 Gene3D G3DSA:3.40.50.620 206 380 1.3E-49 T 11-11-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 1 503 49.337 T 11-11-2016 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 SUPERFAMILY SSF52317 2 184 1.0E-44 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 199 503 1.4E-127 T 11-11-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 6.6E-7 T 11-11-2016 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 6.6E-7 T 11-11-2016 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 6.6E-7 T 11-11-2016 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 SUPERFAMILY SSF52402 186 422 6.17E-51 T 11-11-2016 TW_RS00445 148b540965e5ca6cabfedcfab86f5235 503 Pfam PF00117 Glutamine amidotransferase class-I 6 182 3.6E-35 T 11-11-2016 IPR017926 Glutamine amidotransferase TW_RS01250 79700fa65da9a52e877ea8e3dada5b00 73 Gene3D G3DSA:2.40.50.140 2 73 7.2E-38 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01250 79700fa65da9a52e877ea8e3dada5b00 73 SUPERFAMILY SSF50249 4 72 1.54E-25 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01250 79700fa65da9a52e877ea8e3dada5b00 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 1.2E-27 T 11-11-2016 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 TW_RS01250 79700fa65da9a52e877ea8e3dada5b00 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 8.7E-36 T 11-11-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TW_RS01250 79700fa65da9a52e877ea8e3dada5b00 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.032 T 11-11-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TW_RS02410 9564f86d56abb5ed09f1c0df0f006284 294 SUPERFAMILY SSF54534 187 284 1.22E-32 T 11-11-2016 TW_RS02410 9564f86d56abb5ed09f1c0df0f006284 294 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 203 284 2.8E-19 T 11-11-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 TW_RS02410 9564f86d56abb5ed09f1c0df0f006284 294 Gene3D G3DSA:3.10.50.40 187 288 1.7E-30 T 11-11-2016 TW_RS04280 57c440fbb0a222c20c2f3b0179d9fc77 550 SUPERFAMILY SSF54184 412 466 6.93E-7 T 11-11-2016 TW_RS04280 57c440fbb0a222c20c2f3b0179d9fc77 550 Gene3D G3DSA:3.30.200.20 10 82 3.2E-4 T 11-11-2016 TW_RS04280 57c440fbb0a222c20c2f3b0179d9fc77 550 SUPERFAMILY SSF56112 9 260 6.53E-21 T 11-11-2016 IPR011009 Protein kinase-like domain TW_RS04280 57c440fbb0a222c20c2f3b0179d9fc77 550 SMART SM00740 344 409 8.2E-8 T 11-11-2016 IPR005543 PASTA domain TW_RS04280 57c440fbb0a222c20c2f3b0179d9fc77 550 SMART SM00740 413 466 9.5 T 11-11-2016 IPR005543 PASTA domain TW_RS04280 57c440fbb0a222c20c2f3b0179d9fc77 550 Gene3D G3DSA:1.10.510.10 121 260 1.2E-13 T 11-11-2016 TW_RS04280 57c440fbb0a222c20c2f3b0179d9fc77 550 Pfam PF03793 PASTA domain 349 408 2.0E-13 T 11-11-2016 IPR005543 PASTA domain TW_RS04280 57c440fbb0a222c20c2f3b0179d9fc77 550 SMART SM00220 14 271 0.0079 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TW_RS04280 57c440fbb0a222c20c2f3b0179d9fc77 550 SUPERFAMILY SSF54184 348 408 7.72E-6 T 11-11-2016 TW_RS04280 57c440fbb0a222c20c2f3b0179d9fc77 550 Pfam PF00069 Protein kinase domain 91 255 2.2E-8 T 11-11-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TW_RS03805 6637295a84a5a81e73367de7174b082e 281 Gene3D G3DSA:3.60.10.10 1 280 2.8E-67 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS03805 6637295a84a5a81e73367de7174b082e 281 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 3 279 2.1E-47 T 11-11-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 TW_RS03805 6637295a84a5a81e73367de7174b082e 281 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 256 7.1E-19 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS03805 6637295a84a5a81e73367de7174b082e 281 SUPERFAMILY SSF56219 2 280 3.14E-55 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS00255 4e60f84566b5b5212543f686d498e86b 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 224 3.0E-24 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TW_RS00255 4e60f84566b5b5212543f686d498e86b 227 Gene3D G3DSA:1.10.10.10 128 225 1.2E-33 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS00255 4e60f84566b5b5212543f686d498e86b 227 SMART SM00862 149 224 4.6E-24 T 11-11-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TW_RS00255 4e60f84566b5b5212543f686d498e86b 227 SUPERFAMILY SSF52172 1 181 1.99E-41 T 11-11-2016 IPR011006 CheY-like superfamily TW_RS00255 4e60f84566b5b5212543f686d498e86b 227 Gene3D G3DSA:3.40.50.2300 2 123 1.9E-40 T 11-11-2016 TW_RS00255 4e60f84566b5b5212543f686d498e86b 227 SMART SM00448 4 115 1.8E-43 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TW_RS00255 4e60f84566b5b5212543f686d498e86b 227 Pfam PF00072 Response regulator receiver domain 6 115 7.0E-27 T 11-11-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TW_RS01125 549a178a60576607b1dd7bb3e599ce56 227 Gene3D G3DSA:3.40.50.300 1 219 7.0E-60 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01125 549a178a60576607b1dd7bb3e599ce56 227 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS01125 549a178a60576607b1dd7bb3e599ce56 227 PIRSF PIRSF039137 1 227 7.1E-103 T 11-11-2016 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 TW_RS01125 549a178a60576607b1dd7bb3e599ce56 227 SMART SM00382 20 204 2.7E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS01125 549a178a60576607b1dd7bb3e599ce56 227 Pfam PF00005 ABC transporter 12 155 3.1E-31 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS01125 549a178a60576607b1dd7bb3e599ce56 227 SUPERFAMILY SSF52540 2 225 1.04E-57 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02635 1a2745bce7554fbc7a254ccdd04dd640 95 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 83 1.2E-20 T 11-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02635 1a2745bce7554fbc7a254ccdd04dd640 95 Pfam PF01649 Ribosomal protein S20 2 83 3.5E-24 T 11-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02635 1a2745bce7554fbc7a254ccdd04dd640 95 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 22 83 1.0E-27 T 11-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02635 1a2745bce7554fbc7a254ccdd04dd640 95 SUPERFAMILY SSF46992 3 85 3.79E-24 T 11-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02635 1a2745bce7554fbc7a254ccdd04dd640 95 Gene3D G3DSA:1.20.58.110 2 86 2.2E-25 T 11-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02635 1a2745bce7554fbc7a254ccdd04dd640 95 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 15.227 T 11-11-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS03380 35e0f9b28adf35f6237bc6882aaa5011 410 Pfam PF00877 NlpC/P60 family 303 402 6.5E-18 T 11-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain TW_RS03380 35e0f9b28adf35f6237bc6882aaa5011 410 Gene3D G3DSA:3.90.1720.10 282 398 6.5E-32 T 11-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain TW_RS03380 35e0f9b28adf35f6237bc6882aaa5011 410 SUPERFAMILY SSF54001 283 401 6.38E-32 T 11-11-2016 TW_RS03680 0b6112b3a8f32e9ebe8b5f6c0a36e640 184 SMART SM00756 8 150 2.2E-46 T 11-11-2016 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 TW_RS03680 0b6112b3a8f32e9ebe8b5f6c0a36e640 184 Pfam PF07884 Vitamin K epoxide reductase family 14 145 3.0E-25 T 11-11-2016 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 TW_RS01725 49ac5f57766bb3d153610a9a20b9399c 285 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 8 274 4.6E-56 T 11-11-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 TW_RS01725 49ac5f57766bb3d153610a9a20b9399c 285 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 10 267 3.8E-21 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS01725 49ac5f57766bb3d153610a9a20b9399c 285 Gene3D G3DSA:3.60.10.10 8 274 4.3E-62 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS01725 49ac5f57766bb3d153610a9a20b9399c 285 SUPERFAMILY SSF56219 8 274 1.27E-58 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS01725 49ac5f57766bb3d153610a9a20b9399c 285 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 228 239 - T 11-11-2016 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 TW_RS03325 cab01686e85dae9d9757129cf2db98a6 822 Gene3D G3DSA:3.20.20.210 458 700 2.7E-35 T 11-11-2016 TW_RS03325 cab01686e85dae9d9757129cf2db98a6 822 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 455 696 2.7E-43 T 11-11-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 TW_RS03325 cab01686e85dae9d9757129cf2db98a6 822 Gene3D G3DSA:3.20.20.210 5 388 1.8E-92 T 11-11-2016 TW_RS03325 cab01686e85dae9d9757129cf2db98a6 822 SUPERFAMILY SSF51726 5 391 8.11E-69 T 11-11-2016 TW_RS03325 cab01686e85dae9d9757129cf2db98a6 822 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 317 9.3E-94 T 11-11-2016 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 TW_RS03325 cab01686e85dae9d9757129cf2db98a6 822 SUPERFAMILY SSF51726 418 699 8.24E-38 T 11-11-2016 TW_RS02820 7ef9657a7a6ade9dd630946b83c21ab3 161 Gene3D G3DSA:3.30.420.10 4 142 1.5E-44 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TW_RS02820 7ef9657a7a6ade9dd630946b83c21ab3 161 Pfam PF00075 RNase H 5 140 1.4E-34 T 11-11-2016 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 TW_RS02820 7ef9657a7a6ade9dd630946b83c21ab3 161 Hamap MF_00042 Ribonuclease H [rnhA]. 3 149 25.867 T 11-11-2016 IPR022892 Ribonuclease H GO:0004523 TW_RS02820 7ef9657a7a6ade9dd630946b83c21ab3 161 SUPERFAMILY SSF53098 5 143 2.53E-41 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TW_RS00665 1d643c741e3fd9c3895ce20701048b07 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.13 T 11-11-2016 IPR023036 Ribosomal protein S14, bacterial/plastid TW_RS00665 1d643c741e3fd9c3895ce20701048b07 101 SUPERFAMILY SSF57716 3 101 4.42E-32 T 11-11-2016 TW_RS00665 1d643c741e3fd9c3895ce20701048b07 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 4.7E-24 T 11-11-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS00665 1d643c741e3fd9c3895ce20701048b07 101 Gene3D G3DSA:4.10.830.10 42 101 2.8E-28 T 11-11-2016 TW_RS01095 3dd7eb1f15441be3c50becf44cbb4876 65 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 45 8.2E-10 T 11-11-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01095 3dd7eb1f15441be3c50becf44cbb4876 65 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 65 11.426 T 11-11-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01095 3dd7eb1f15441be3c50becf44cbb4876 65 SUPERFAMILY SSF57829 2 37 5.49E-7 T 11-11-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 TW_RS01095 3dd7eb1f15441be3c50becf44cbb4876 65 Pfam PF01783 Ribosomal L32p protein family 2 44 7.0E-10 T 11-11-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01950 f5b5e1061dbb97e8f0860773b36c993b 148 Gene3D G3DSA:2.40.50.140 5 113 1.1E-23 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01950 f5b5e1061dbb97e8f0860773b36c993b 148 Pfam PF00436 Single-strand binding protein family 6 103 7.5E-17 T 11-11-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 TW_RS01950 f5b5e1061dbb97e8f0860773b36c993b 148 SUPERFAMILY SSF50249 6 117 6.85E-25 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01950 f5b5e1061dbb97e8f0860773b36c993b 148 Hamap MF_00984 Single-stranded DNA-binding protein. 6 111 23.857 T 11-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TW_RS01950 f5b5e1061dbb97e8f0860773b36c993b 148 PIRSF PIRSF002070 2 148 7.6E-30 T 11-11-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TW_RS00285 a6cbec3c62109b155f7b4bd84ba92b17 425 Gene3D G3DSA:3.60.120.10 30 424 1.6E-58 T 11-11-2016 IPR005801 ADC synthase GO:0009058 TW_RS00285 a6cbec3c62109b155f7b4bd84ba92b17 425 Pfam PF00425 chorismate binding enzyme 152 416 1.2E-64 T 11-11-2016 IPR015890 Chorismate-utilising enzyme, C-terminal TW_RS00285 a6cbec3c62109b155f7b4bd84ba92b17 425 SUPERFAMILY SSF56322 29 424 5.63E-66 T 11-11-2016 IPR005801 ADC synthase GO:0009058 TW_RS02905 6570b474963d97535a1f1fd9e27b7600 581 SUPERFAMILY SSF56601 229 571 2.73E-68 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like TW_RS02905 6570b474963d97535a1f1fd9e27b7600 581 SUPERFAMILY SSF56519 47 228 5.1E-34 T 11-11-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TW_RS02905 6570b474963d97535a1f1fd9e27b7600 581 Gene3D G3DSA:3.40.710.10 236 565 4.7E-72 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like TW_RS02905 6570b474963d97535a1f1fd9e27b7600 581 Pfam PF03717 Penicillin-binding Protein dimerisation domain 51 208 3.8E-12 T 11-11-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TW_RS02905 6570b474963d97535a1f1fd9e27b7600 581 Pfam PF00905 Penicillin binding protein transpeptidase domain 254 559 5.9E-54 T 11-11-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TW_RS02905 6570b474963d97535a1f1fd9e27b7600 581 Gene3D G3DSA:3.90.1310.10 141 235 1.2E-23 T 11-11-2016 TW_RS02260 6f65fcd674070ec1a2f5cd96da329089 263 Gene3D G3DSA:3.40.1280.10 111 263 8.7E-45 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TW_RS02260 6f65fcd674070ec1a2f5cd96da329089 263 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 26 98 6.7E-13 T 11-11-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 TW_RS02260 6f65fcd674070ec1a2f5cd96da329089 263 SMART SM00967 25 99 9.1E-11 T 11-11-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 TW_RS02260 6f65fcd674070ec1a2f5cd96da329089 263 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 23 263 9.5E-51 T 11-11-2016 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 TW_RS02260 6f65fcd674070ec1a2f5cd96da329089 263 SUPERFAMILY SSF75217 87 263 6.02E-39 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases TW_RS02260 6f65fcd674070ec1a2f5cd96da329089 263 Gene3D G3DSA:3.30.1330.30 22 93 9.5E-9 T 11-11-2016 IPR029064 50S ribosomal protein L30e-like TW_RS02260 6f65fcd674070ec1a2f5cd96da329089 263 SUPERFAMILY SSF55315 24 95 2.0E-8 T 11-11-2016 IPR029064 50S ribosomal protein L30e-like TW_RS02260 6f65fcd674070ec1a2f5cd96da329089 263 Pfam PF00588 SpoU rRNA Methylase family 114 259 2.2E-33 T 11-11-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TW_RS02880 f171fe54aecbefc43b95d38f96a70896 370 Pfam PF01098 Cell cycle protein 15 366 5.2E-76 T 11-11-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 TW_RS02880 f171fe54aecbefc43b95d38f96a70896 370 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 13 366 2.9E-106 T 11-11-2016 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 TW_RS01655 60d60f5ec2ac9368992db2cebd56b9bc 115 PRINTS PR00061 Ribosomal protein L19 signature 33 62 7.7E-38 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01655 60d60f5ec2ac9368992db2cebd56b9bc 115 PRINTS PR00061 Ribosomal protein L19 signature 87 112 7.7E-38 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01655 60d60f5ec2ac9368992db2cebd56b9bc 115 PRINTS PR00061 Ribosomal protein L19 signature 3 32 7.7E-38 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01655 60d60f5ec2ac9368992db2cebd56b9bc 115 PIRSF PIRSF002191 2 115 3.8E-48 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01655 60d60f5ec2ac9368992db2cebd56b9bc 115 SUPERFAMILY SSF50104 4 114 9.23E-44 T 11-11-2016 IPR008991 Translation protein SH3-like domain TW_RS01655 60d60f5ec2ac9368992db2cebd56b9bc 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 28.507 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01655 60d60f5ec2ac9368992db2cebd56b9bc 115 Pfam PF01245 Ribosomal protein L19 5 112 5.6E-47 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01655 60d60f5ec2ac9368992db2cebd56b9bc 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 112 2.9E-46 T 11-11-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01655 60d60f5ec2ac9368992db2cebd56b9bc 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 11-11-2016 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS04110 a6ed8da9727a594aa3aff8403e57c301 269 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 268 5.0E-66 T 11-11-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 TW_RS04110 a6ed8da9727a594aa3aff8403e57c301 269 SUPERFAMILY SSF56219 2 269 1.96E-64 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS04110 a6ed8da9727a594aa3aff8403e57c301 269 Gene3D G3DSA:3.60.10.10 2 268 2.0E-69 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS04110 a6ed8da9727a594aa3aff8403e57c301 269 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 261 1.5E-23 T 11-11-2016 IPR005135 Endonuclease/exonuclease/phosphatase TW_RS04110 a6ed8da9727a594aa3aff8403e57c301 269 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 268 3.5E-60 T 11-11-2016 TW_RS02380 15393506cef435e49329580ea01dd397 298 Pfam PF01026 TatD related DNase 21 295 4.0E-62 T 11-11-2016 IPR001130 TatD family GO:0016788 TW_RS02380 15393506cef435e49329580ea01dd397 298 Gene3D G3DSA:3.20.20.140 14 296 7.0E-73 T 11-11-2016 TW_RS02380 15393506cef435e49329580ea01dd397 298 SUPERFAMILY SSF51556 116 297 2.86E-67 T 11-11-2016 IPR032466 Metal-dependent hydrolase TW_RS02380 15393506cef435e49329580ea01dd397 298 SUPERFAMILY SSF51556 18 87 2.86E-67 T 11-11-2016 IPR032466 Metal-dependent hydrolase TW_RS02380 15393506cef435e49329580ea01dd397 298 PIRSF PIRSF005902 10 298 2.3E-77 T 11-11-2016 IPR001130 TatD family GO:0016788 TW_RS01030 2d1724ca6b6f9bc7764430769de5bc95 194 Pfam PF01478 Type IV leader peptidase family 43 141 1.3E-7 T 11-11-2016 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 TW_RS02515 413473b085e5287901acc742c862bce1 319 Pfam PF14527 WhiA LAGLIDADG-like domain 129 218 1.1E-22 T 11-11-2016 TW_RS02515 413473b085e5287901acc742c862bce1 319 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 7 308 23.547 T 11-11-2016 IPR003802 Sporulation regulator WhiA GO:0043937 TW_RS02515 413473b085e5287901acc742c862bce1 319 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 15 306 5.1E-49 T 11-11-2016 TW_RS02515 413473b085e5287901acc742c862bce1 319 SUPERFAMILY SSF55608 117 221 1.0E-6 T 11-11-2016 IPR027434 Homing endonuclease GO:0004519 TW_RS02515 413473b085e5287901acc742c862bce1 319 Pfam PF02650 WhiA C-terminal HTH domain 225 304 1.3E-16 T 11-11-2016 IPR023054 Sporulation regulator WhiA, C-terminal TW_RS02515 413473b085e5287901acc742c862bce1 319 Gene3D G3DSA:3.10.28.10 117 215 7.5E-4 T 11-11-2016 IPR027434 Homing endonuclease GO:0004519 TW_RS02515 413473b085e5287901acc742c862bce1 319 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 25 105 2.7E-12 T 11-11-2016 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain TW_RS02735 19c7ad5934df23744537db8058a5047a 152 SUPERFAMILY SSF52833 7 151 2.86E-35 T 11-11-2016 IPR012336 Thioredoxin-like fold TW_RS02735 19c7ad5934df23744537db8058a5047a 152 Pfam PF00578 AhpC/TSA family 9 131 6.0E-26 T 11-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TW_RS02735 19c7ad5934df23744537db8058a5047a 152 Gene3D G3DSA:3.40.30.10 4 151 1.5E-37 T 11-11-2016 IPR012336 Thioredoxin-like fold TW_RS02745 c76e4f9684d887607c81f5a2f91bd94d 339 SUPERFAMILY SSF55048 162 212 7.59E-11 T 11-11-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 TW_RS02745 c76e4f9684d887607c81f5a2f91bd94d 339 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 21 322 2.0E-10 T 11-11-2016 IPR020801 Polyketide synthase, acyl transferase domain TW_RS02745 c76e4f9684d887607c81f5a2f91bd94d 339 Pfam PF00698 Acyl transferase domain 120 239 2.4E-8 T 11-11-2016 IPR014043 Acyl transferase TW_RS02745 c76e4f9684d887607c81f5a2f91bd94d 339 Gene3D G3DSA:3.30.70.250 161 222 1.5E-17 T 11-11-2016 TW_RS02745 c76e4f9684d887607c81f5a2f91bd94d 339 SUPERFAMILY SSF52151 19 154 1.1E-47 T 11-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 TW_RS02745 c76e4f9684d887607c81f5a2f91bd94d 339 SUPERFAMILY SSF52151 216 333 1.1E-47 T 11-11-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 TW_RS02745 c76e4f9684d887607c81f5a2f91bd94d 339 Gene3D G3DSA:3.40.366.10 19 153 4.1E-37 T 11-11-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 TW_RS02745 c76e4f9684d887607c81f5a2f91bd94d 339 Gene3D G3DSA:3.40.366.10 223 331 4.1E-37 T 11-11-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 TW_RS00955 cb2dbe95f15bab755e53c2e26a02be9b 280 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 146 255 1.3E-21 T 11-11-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 TW_RS00955 cb2dbe95f15bab755e53c2e26a02be9b 280 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 6 114 1.0E-9 T 11-11-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 TW_RS00955 cb2dbe95f15bab755e53c2e26a02be9b 280 SUPERFAMILY SSF52540 145 256 1.37E-16 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00955 cb2dbe95f15bab755e53c2e26a02be9b 280 Gene3D G3DSA:3.40.50.300 125 262 5.9E-33 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00955 cb2dbe95f15bab755e53c2e26a02be9b 280 SUPERFAMILY SSF56214 2 114 1.33E-14 T 11-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 TW_RS00955 cb2dbe95f15bab755e53c2e26a02be9b 280 Gene3D G3DSA:3.90.470.20 2 114 4.5E-20 T 11-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 TW_RS00955 cb2dbe95f15bab755e53c2e26a02be9b 280 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 109 1.1E-9 T 11-11-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 TW_RS00955 cb2dbe95f15bab755e53c2e26a02be9b 280 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 133 245 1.8E-26 T 11-11-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 TW_RS00955 cb2dbe95f15bab755e53c2e26a02be9b 280 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 3 114 3.1E-15 T 11-11-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 PRINTS PR00481 Cytosol aminopeptidase signature 249 266 1.6E-48 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 PRINTS PR00481 Cytosol aminopeptidase signature 330 350 1.6E-48 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 PRINTS PR00481 Cytosol aminopeptidase signature 308 329 1.6E-48 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 PRINTS PR00481 Cytosol aminopeptidase signature 271 292 1.6E-48 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 PRINTS PR00481 Cytosol aminopeptidase signature 358 373 1.6E-48 T 11-11-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 334 341 - T 11-11-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 Gene3D G3DSA:3.40.220.10 21 165 8.0E-17 T 11-11-2016 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 38 136 2.6E-12 T 11-11-2016 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 173 487 6.1E-103 T 11-11-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 SUPERFAMILY SSF53187 168 490 2.45E-102 T 11-11-2016 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 SUPERFAMILY SSF52949 21 145 4.36E-17 T 11-11-2016 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 Gene3D G3DSA:3.40.630.10 166 492 5.7E-114 T 11-11-2016 TW_RS01410 ae07786e84f24745f83114b3defe361c 502 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 8 495 30.353 T 11-11-2016 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 TW_RS03945 87f873a3d5ddc68381633030135b7c78 227 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 225 1.3E-89 T 11-11-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TW_RS03945 87f873a3d5ddc68381633030135b7c78 227 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 3.3E-44 T 11-11-2016 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein TW_RS03945 87f873a3d5ddc68381633030135b7c78 227 Gene3D G3DSA:3.30.190.20 18 68 5.3E-40 T 11-11-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 TW_RS03945 87f873a3d5ddc68381633030135b7c78 227 Gene3D G3DSA:3.30.190.20 161 225 5.3E-40 T 11-11-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 TW_RS03945 87f873a3d5ddc68381633030135b7c78 227 SUPERFAMILY SSF56808 6 224 8.11E-71 T 11-11-2016 IPR023674 Ribosomal protein L1-like TW_RS03945 87f873a3d5ddc68381633030135b7c78 227 Gene3D G3DSA:3.40.50.790 69 156 2.9E-35 T 11-11-2016 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich TW_RS03945 87f873a3d5ddc68381633030135b7c78 227 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 226 37.872 T 11-11-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TW_RS03945 87f873a3d5ddc68381633030135b7c78 227 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 11-11-2016 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS03945 87f873a3d5ddc68381633030135b7c78 227 PIRSF PIRSF002155 1 227 4.7E-67 T 11-11-2016 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS04235 399239367854bc29e09086d6a6141f6e 280 Gene3D G3DSA:3.40.50.1000 137 276 7.8E-32 T 11-11-2016 IPR023214 HAD-like domain TW_RS04235 399239367854bc29e09086d6a6141f6e 280 Gene3D G3DSA:1.10.150.240 80 136 1.2E-19 T 11-11-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 TW_RS04235 399239367854bc29e09086d6a6141f6e 280 Pfam PF13419 Haloacid dehalogenase-like hydrolase 69 249 2.6E-23 T 11-11-2016 IPR023214 HAD-like domain TW_RS04235 399239367854bc29e09086d6a6141f6e 280 SUPERFAMILY SSF56784 59 276 6.67E-48 T 11-11-2016 IPR023214 HAD-like domain TW_RS04155 d9e5af6b66fe0477874f358e17deb2d3 167 Pfam PF05768 Glutaredoxin-like domain (DUF836) 40 128 2.9E-20 T 11-11-2016 IPR008554 Glutaredoxin-like TW_RS04155 d9e5af6b66fe0477874f358e17deb2d3 167 Gene3D G3DSA:3.40.30.10 41 130 4.3E-15 T 11-11-2016 IPR012336 Thioredoxin-like fold TW_RS04155 d9e5af6b66fe0477874f358e17deb2d3 167 SUPERFAMILY SSF52833 41 127 2.95E-8 T 11-11-2016 IPR012336 Thioredoxin-like fold TW_RS04105 207e053f9010c20bd40c6ea96d99d7d8 184 Pfam PF00156 Phosphoribosyl transferase domain 62 158 6.4E-9 T 11-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 TW_RS04105 207e053f9010c20bd40c6ea96d99d7d8 184 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 184 23.614 T 11-11-2016 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS04105 207e053f9010c20bd40c6ea96d99d7d8 184 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 176 2.1E-37 T 11-11-2016 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TW_RS04105 207e053f9010c20bd40c6ea96d99d7d8 184 SUPERFAMILY SSF53271 2 179 2.49E-36 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like TW_RS04105 207e053f9010c20bd40c6ea96d99d7d8 184 Gene3D G3DSA:3.40.50.2020 7 179 6.5E-48 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like TW_RS03235 a017e6c75291db84e23205c7b9dd83c7 330 Pfam PF00005 ABC transporter 57 193 1.6E-25 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS03235 a017e6c75291db84e23205c7b9dd83c7 330 SMART SM00382 65 242 1.8E-13 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS03235 a017e6c75291db84e23205c7b9dd83c7 330 Gene3D G3DSA:3.40.50.300 39 261 2.2E-53 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03235 a017e6c75291db84e23205c7b9dd83c7 330 SUPERFAMILY SSF52540 38 266 1.38E-52 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 PRINTS PR00148 Enolase signature 37 51 2.5E-45 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 PRINTS PR00148 Enolase signature 333 347 2.5E-45 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 PRINTS PR00148 Enolase signature 161 174 2.5E-45 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 PRINTS PR00148 Enolase signature 107 123 2.5E-45 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 PRINTS PR00148 Enolase signature 362 379 2.5E-45 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 PRINTS PR00148 Enolase signature 310 321 2.5E-45 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 418 5.0E-125 T 11-11-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 SMART SM01192 139 424 1.1E-200 T 11-11-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 SMART SM01193 4 134 1.9E-88 T 11-11-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 421 2.1E-197 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 SUPERFAMILY SSF51604 139 419 1.5E-119 T 11-11-2016 IPR029065 Enolase C-terminal domain-like TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 SUPERFAMILY SSF54826 3 137 3.69E-54 T 11-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 Gene3D G3DSA:3.30.390.10 4 125 2.1E-53 T 11-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 ProSitePatterns PS00164 Enolase signature. 333 346 - T 11-11-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 Gene3D G3DSA:3.20.20.120 130 418 2.6E-123 T 11-11-2016 IPR029065 Enolase C-terminal domain-like TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 Pfam PF03952 Enolase, N-terminal domain 4 134 3.3E-56 T 11-11-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 Hamap MF_00318 Enolase [eno]. 2 410 43.641 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04305 eae1d057abb71f520f6bc01ebf07644b 428 PIRSF PIRSF001400 1 422 3.7E-183 T 11-11-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS03410 b81a206cb1516a3210881c8b83e95ac8 286 Gene3D G3DSA:3.40.50.300 2 152 2.7E-33 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03410 b81a206cb1516a3210881c8b83e95ac8 286 Pfam PF01715 IPP transferase 21 257 5.5E-59 T 11-11-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TW_RS03410 b81a206cb1516a3210881c8b83e95ac8 286 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 1 280 19.953 T 11-11-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TW_RS03410 b81a206cb1516a3210881c8b83e95ac8 286 SUPERFAMILY SSF52540 6 129 1.17E-5 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03410 b81a206cb1516a3210881c8b83e95ac8 286 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 2 267 1.7E-60 T 11-11-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TW_RS03410 b81a206cb1516a3210881c8b83e95ac8 286 Gene3D G3DSA:1.10.287.890 179 256 2.1E-20 T 11-11-2016 TW_RS02830 56f4a7e4c66613a707edc9d2b1ff1bec 147 Pfam PF03477 ATP cone domain 47 132 1.2E-15 T 11-11-2016 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TW_RS02830 56f4a7e4c66613a707edc9d2b1ff1bec 147 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 7.6E-47 T 11-11-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TW_RS02830 56f4a7e4c66613a707edc9d2b1ff1bec 147 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 147 70.861 T 11-11-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TW_RS02005 8dbc28afcb9db514924fda256ceff8aa 231 SUPERFAMILY SSF53597 20 181 2.52E-19 T 11-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 TW_RS02005 8dbc28afcb9db514924fda256ceff8aa 231 Gene3D G3DSA:3.40.430.10 17 179 8.5E-19 T 11-11-2016 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 TW_RS02005 8dbc28afcb9db514924fda256ceff8aa 231 Pfam PF01872 RibD C-terminal domain 20 179 1.1E-12 T 11-11-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TW_RS00210 9e8466eff5533dd62b545a1004bde8e7 613 Pfam PF09913 Predicted membrane protein (DUF2142) 46 427 4.1E-75 T 11-11-2016 IPR018674 Protein of unknown function DUF2142, membrane TW_RS01530 e31cbf5d308767b267e776e5b972a247 207 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 117 130 - T 11-11-2016 IPR033135 ClpP, histidine active site TW_RS01530 e31cbf5d308767b267e776e5b972a247 207 PRINTS PR00127 Clp protease catalytic subunit P signature 95 112 8.7E-42 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TW_RS01530 e31cbf5d308767b267e776e5b972a247 207 PRINTS PR00127 Clp protease catalytic subunit P signature 64 84 8.7E-42 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TW_RS01530 e31cbf5d308767b267e776e5b972a247 207 PRINTS PR00127 Clp protease catalytic subunit P signature 116 135 8.7E-42 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TW_RS01530 e31cbf5d308767b267e776e5b972a247 207 PRINTS PR00127 Clp protease catalytic subunit P signature 24 39 8.7E-42 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TW_RS01530 e31cbf5d308767b267e776e5b972a247 207 PRINTS PR00127 Clp protease catalytic subunit P signature 175 194 8.7E-42 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TW_RS01530 e31cbf5d308767b267e776e5b972a247 207 Pfam PF00574 Clp protease 21 199 3.6E-73 T 11-11-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TW_RS01530 e31cbf5d308767b267e776e5b972a247 207 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 95 106 - T 11-11-2016 IPR018215 ClpP, Ser active site TW_RS01530 e31cbf5d308767b267e776e5b972a247 207 Gene3D G3DSA:3.90.226.10 21 201 2.3E-72 T 11-11-2016 IPR029045 ClpP/crotonase-like domain TW_RS01530 e31cbf5d308767b267e776e5b972a247 207 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 8 200 39.181 T 11-11-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TW_RS01530 e31cbf5d308767b267e776e5b972a247 207 SUPERFAMILY SSF52096 17 200 3.08E-62 T 11-11-2016 IPR029045 ClpP/crotonase-like domain TW_RS02405 dd6cb948150e433784bd47aec8f45271 93 Pfam PF02416 mttA/Hcf106 family 6 49 1.6E-11 T 11-11-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TW_RS02405 dd6cb948150e433784bd47aec8f45271 93 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 77 18.245 T 11-11-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TW_RS02405 dd6cb948150e433784bd47aec8f45271 93 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 48 6.1E-16 T 11-11-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TW_RS00960 57c037fbafe48aff6f0cfc18263e7afe 501 Pfam PF00583 Acetyltransferase (GNAT) family 406 479 3.0E-15 T 11-11-2016 IPR000182 GNAT domain GO:0008080 TW_RS00960 57c037fbafe48aff6f0cfc18263e7afe 501 Pfam PF00814 Glycoprotease family 36 140 1.8E-11 T 11-11-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 TW_RS00960 57c037fbafe48aff6f0cfc18263e7afe 501 SUPERFAMILY SSF53067 1 98 5.96E-16 T 11-11-2016 TW_RS00960 57c037fbafe48aff6f0cfc18263e7afe 501 Gene3D G3DSA:3.40.630.30 357 491 5.9E-30 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase TW_RS00960 57c037fbafe48aff6f0cfc18263e7afe 501 SUPERFAMILY SSF55729 362 501 2.7E-30 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase TW_RS00960 57c037fbafe48aff6f0cfc18263e7afe 501 Gene3D G3DSA:3.30.420.40 1 104 6.2E-18 T 11-11-2016 TW_RS00960 57c037fbafe48aff6f0cfc18263e7afe 501 Gene3D G3DSA:3.30.420.40 153 178 6.2E-18 T 11-11-2016 TW_RS00960 57c037fbafe48aff6f0cfc18263e7afe 501 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 342 7.7E-59 T 11-11-2016 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 TW_RS02195 d4ce32d4bc3848bf4765013626cf23f1 319 SUPERFAMILY SSF53328 5 217 8.9E-37 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TW_RS02195 d4ce32d4bc3848bf4765013626cf23f1 319 Pfam PF02911 Formyl transferase, C-terminal domain 217 315 1.3E-22 T 11-11-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TW_RS02195 d4ce32d4bc3848bf4765013626cf23f1 319 Gene3D G3DSA:3.40.50.170 4 218 7.7E-39 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TW_RS02195 d4ce32d4bc3848bf4765013626cf23f1 319 Gene3D G3DSA:3.10.25.10 222 316 4.1E-19 T 11-11-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TW_RS02195 d4ce32d4bc3848bf4765013626cf23f1 319 Pfam PF00551 Formyl transferase 74 170 4.1E-22 T 11-11-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TW_RS02195 d4ce32d4bc3848bf4765013626cf23f1 319 SUPERFAMILY SSF50486 219 316 4.55E-21 T 11-11-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 TW_RS03800 17e89a72b1dea97f56f3e93b2544ebcd 408 SUPERFAMILY SSF103473 12 390 1.7E-30 T 11-11-2016 IPR020846 Major facilitator superfamily domain TW_RS03800 17e89a72b1dea97f56f3e93b2544ebcd 408 Gene3D G3DSA:1.20.1250.20 208 386 5.7E-10 T 11-11-2016 TW_RS03800 17e89a72b1dea97f56f3e93b2544ebcd 408 Pfam PF07690 Major Facilitator Superfamily 33 273 4.8E-12 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TW_RS03800 17e89a72b1dea97f56f3e93b2544ebcd 408 Gene3D G3DSA:1.20.1250.20 16 195 1.5E-13 T 11-11-2016 TW_RS03985 66953d079f475c36cc4d23048f4affff 140 Gene3D G3DSA:3.10.129.10 8 139 8.9E-19 T 11-11-2016 IPR029069 HotDog domain TW_RS03985 66953d079f475c36cc4d23048f4affff 140 PIRSF PIRSF018072 2 140 1.6E-42 T 11-11-2016 IPR016709 Uncharacterised protein family UPF0336 TW_RS03985 66953d079f475c36cc4d23048f4affff 140 SUPERFAMILY SSF54637 10 138 1.13E-26 T 11-11-2016 IPR029069 HotDog domain TW_RS03985 66953d079f475c36cc4d23048f4affff 140 Pfam PF13452 N-terminal half of MaoC dehydratase 11 95 1.4E-17 T 11-11-2016 TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 7.2E-35 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 7.2E-35 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 7.2E-35 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 7.2E-35 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 Pfam PF01926 50S ribosome-binding GTPase 5 115 1.5E-22 T 11-11-2016 IPR006073 GTP binding domain GO:0005525 TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 342 2.6E-107 T 11-11-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 SUPERFAMILY SSF81271 260 341 1.57E-33 T 11-11-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 Gene3D G3DSA:3.40.50.300 4 131 1.5E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 Gene3D G3DSA:3.40.50.300 186 241 1.5E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 Pfam PF06071 Protein of unknown function (DUF933) 260 342 4.8E-37 T 11-11-2016 IPR013029 Domain of unknown function DUF933 TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 SUPERFAMILY SSF52540 3 282 4.94E-60 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 Gene3D G3DSA:1.10.150.300 132 170 5.7E-7 T 11-11-2016 IPR023192 TGS-like domain TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 PIRSF PIRSF006641 1 344 1.0E-119 T 11-11-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 TW_RS03590 c7cebe63b34d6745ad48309845c2da50 344 Gene3D G3DSA:3.10.20.30 242 342 1.6E-41 T 11-11-2016 IPR012675 Beta-grasp domain TW_RS02845 5ee4fa069b7c1110492349cf5c2f31e3 143 Gene3D G3DSA:2.60.200.20 42 136 1.7E-23 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TW_RS02845 5ee4fa069b7c1110492349cf5c2f31e3 143 SUPERFAMILY SSF49879 28 136 1.42E-27 T 11-11-2016 IPR008984 SMAD/FHA domain GO:0005515 TW_RS02845 5ee4fa069b7c1110492349cf5c2f31e3 143 Pfam PF00498 FHA domain 68 129 1.1E-16 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TW_RS02845 5ee4fa069b7c1110492349cf5c2f31e3 143 SMART SM00240 65 115 1.4E-11 T 11-11-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 TW_RS01350 a984bc27d7f38e2569109031e99b7185 150 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 48 56 1.3E-10 T 11-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 TW_RS01350 a984bc27d7f38e2569109031e99b7185 150 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 88 103 1.3E-10 T 11-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 TW_RS01350 a984bc27d7f38e2569109031e99b7185 150 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 128 144 1.3E-10 T 11-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 TW_RS01350 a984bc27d7f38e2569109031e99b7185 150 Pfam PF01252 Signal peptidase (SPase) II 12 143 8.3E-26 T 11-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 TW_RS01350 a984bc27d7f38e2569109031e99b7185 150 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 3 150 13.077 T 11-11-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 TW_RS03455 5f1065e1aad243ed16f2b84614b610d2 86 Pfam PF02467 Transcription factor WhiB 3 71 1.8E-24 T 11-11-2016 IPR003482 Transcription factor WhiB TW_RS03455 5f1065e1aad243ed16f2b84614b610d2 86 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 16.594 T 11-11-2016 IPR003482 Transcription factor WhiB TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 SUPERFAMILY SSF101904 501 815 2.22E-94 T 11-11-2016 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 SMART SM00434 9 466 4.6E-250 T 11-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Gene3D G3DSA:2.120.10.90 499 807 2.4E-105 T 11-11-2016 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 30 473 8.7E-143 T 11-11-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 6 809 0.0 T 11-11-2016 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Gene3D G3DSA:3.30.1360.40 238 334 2.5E-31 T 11-11-2016 IPR024946 Arginine repressor C-terminal-like domain TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 811 22.44 T 11-11-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 SUPERFAMILY SSF56719 29 489 7.98E-161 T 11-11-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Gene3D G3DSA:3.90.199.10 29 237 6.6E-104 T 11-11-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Gene3D G3DSA:3.90.199.10 335 400 6.6E-104 T 11-11-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 614 656 5.1E-10 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 770 808 2.2E-5 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 713 760 3.0E-8 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 557 606 3.2E-8 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 508 548 4.9E-11 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TW_RS00030 1b1271208f50ea4ddb4e5e2ef19a96fc 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 661 706 3.7E-9 T 11-11-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TW_RS02955 fd9ee4430eea3146089d178217506605 314 Gene3D G3DSA:3.30.420.40 146 287 6.4E-43 T 11-11-2016 TW_RS02955 fd9ee4430eea3146089d178217506605 314 Pfam PF00480 ROK family 14 309 1.1E-70 T 11-11-2016 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TW_RS02955 fd9ee4430eea3146089d178217506605 314 SUPERFAMILY SSF53067 13 310 7.6E-55 T 11-11-2016 TW_RS02955 fd9ee4430eea3146089d178217506605 314 Gene3D G3DSA:3.30.420.40 13 145 8.7E-39 T 11-11-2016 TW_RS00205 e1f4a161e3026c448fe569ae6e162aa5 242 Pfam PF00535 Glycosyl transferase family 2 7 150 6.2E-23 T 11-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TW_RS00205 e1f4a161e3026c448fe569ae6e162aa5 242 SUPERFAMILY SSF53448 4 211 5.14E-30 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS00205 e1f4a161e3026c448fe569ae6e162aa5 242 Gene3D G3DSA:3.90.550.10 4 199 3.6E-18 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS00940 243b90f3d111c31eb96e3cc51cc2fb5d 232 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 7 221 1.0E-112 T 11-11-2016 TW_RS00940 243b90f3d111c31eb96e3cc51cc2fb5d 232 Pfam PF13829 Domain of unknown function (DUF4191) 6 224 8.0E-49 T 11-11-2016 IPR025445 Protein of unknown function DUF4191 TW_RS01355 188aae1481bd4975a1b211916aabe3c0 303 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 127 141 - T 11-11-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TW_RS01355 188aae1481bd4975a1b211916aabe3c0 303 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 72 296 1.8E-70 T 11-11-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TW_RS01355 188aae1481bd4975a1b211916aabe3c0 303 Pfam PF00849 RNA pseudouridylate synthase 84 235 5.3E-29 T 11-11-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TW_RS01355 188aae1481bd4975a1b211916aabe3c0 303 SUPERFAMILY SSF55120 76 296 1.92E-67 T 11-11-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TW_RS04380 d0014f43524464dcc42b603b9bacd6c3 405 Pfam PF00534 Glycosyl transferases group 1 223 379 5.8E-29 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 TW_RS04380 d0014f43524464dcc42b603b9bacd6c3 405 Gene3D G3DSA:3.40.50.2000 178 379 1.4E-26 T 11-11-2016 TW_RS04380 d0014f43524464dcc42b603b9bacd6c3 405 Pfam PF13439 Glycosyltransferase Family 4 23 194 3.5E-22 T 11-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TW_RS04380 d0014f43524464dcc42b603b9bacd6c3 405 SUPERFAMILY SSF53756 22 403 9.42E-68 T 11-11-2016 TW_RS00640 5481aec3a8b51a328cacbab459b3f53d 378 Gene3D G3DSA:2.30.38.10 205 271 4.1E-6 T 11-11-2016 TW_RS00640 5481aec3a8b51a328cacbab459b3f53d 378 SUPERFAMILY SSF56801 42 375 2.09E-53 T 11-11-2016 TW_RS00640 5481aec3a8b51a328cacbab459b3f53d 378 Pfam PF00501 AMP-binding enzyme 39 277 5.9E-28 T 11-11-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 TW_RS00640 5481aec3a8b51a328cacbab459b3f53d 378 Gene3D G3DSA:3.30.300.30 272 371 1.6E-12 T 11-11-2016 TW_RS00640 5481aec3a8b51a328cacbab459b3f53d 378 Gene3D G3DSA:3.40.50.980 43 204 3.7E-16 T 11-11-2016 TW_RS01285 ec9b8e319e299888273abadeca43ba69 193 Pfam PF06210 Protein of unknown function (DUF1003) 65 167 6.2E-26 T 11-11-2016 IPR010406 Protein of unknown function DUF1003 TW_RS04170 698dd082926c5ac09dcd8ebce16d4446 228 SUPERFAMILY SSF52833 85 213 9.23E-29 T 11-11-2016 IPR012336 Thioredoxin-like fold TW_RS04170 698dd082926c5ac09dcd8ebce16d4446 228 Pfam PF00578 AhpC/TSA family 88 197 5.3E-18 T 11-11-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TW_RS04170 698dd082926c5ac09dcd8ebce16d4446 228 Gene3D G3DSA:3.40.30.10 33 220 1.4E-32 T 11-11-2016 IPR012336 Thioredoxin-like fold TW_RS01855 ae0a63389fab6fc99e6882a42f5ad22f 398 Pfam PF01594 Domain of unknown function DUF20 76 392 2.3E-45 T 11-11-2016 IPR002549 Transmembrane protein TqsA-like TW_RS01860 2f40147dd04b2a7dafc4c3a1639a98df 574 Gene3D G3DSA:1.20.5.620 485 510 7.4E-4 T 11-11-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain TW_RS01860 2f40147dd04b2a7dafc4c3a1639a98df 574 Pfam PF05103 DivIVA protein 15 134 8.9E-10 T 11-11-2016 IPR007793 DivIVA family TW_RS01860 2f40147dd04b2a7dafc4c3a1639a98df 574 SUPERFAMILY SSF58113 63 251 2.09E-5 T 11-11-2016 TW_RS01815 07ca545cf240b696975ec50d1035a213 262 Hamap MF_01416 ATP synthase subunit delta [atpD]. 31 257 10.689 T 11-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 TW_RS01815 07ca545cf240b696975ec50d1035a213 262 Pfam PF00213 ATP synthase delta (OSCP) subunit 105 252 2.6E-19 T 11-11-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210 TW_RS01815 07ca545cf240b696975ec50d1035a213 262 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 217 236 - T 11-11-2016 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210 TW_RS04370 e03413c5fc0e3ae7cb4b6ac22b90b989 226 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 220 35.546 T 11-11-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TW_RS04370 e03413c5fc0e3ae7cb4b6ac22b90b989 226 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 201 1.1E-31 T 11-11-2016 TW_RS04370 e03413c5fc0e3ae7cb4b6ac22b90b989 226 SMART SM01211 2 222 5.2E-92 T 11-11-2016 TW_RS04370 e03413c5fc0e3ae7cb4b6ac22b90b989 226 Gene3D G3DSA:3.40.50.880 2 203 1.5E-36 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS04370 e03413c5fc0e3ae7cb4b6ac22b90b989 226 SUPERFAMILY SSF52317 3 202 1.39E-59 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS04370 e03413c5fc0e3ae7cb4b6ac22b90b989 226 PIRSF PIRSF001586 1 225 1.8E-74 T 11-11-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TW_RS04370 e03413c5fc0e3ae7cb4b6ac22b90b989 226 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 219 8.0E-73 T 11-11-2016 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TW_RS03155 172f379dc85e14f1defd94a2f5965b29 139 Pfam PF07811 TadE-like protein 23 65 7.2E-10 T 11-11-2016 IPR012495 TadE-like TW_RS00180 0692381b697047d72743e51f8f9fb2de 282 Gene3D G3DSA:3.90.550.10 7 255 3.8E-32 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS00180 0692381b697047d72743e51f8f9fb2de 282 SUPERFAMILY SSF53448 9 265 3.72E-42 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS00180 0692381b697047d72743e51f8f9fb2de 282 Pfam PF00535 Glycosyl transferase family 2 10 192 1.1E-20 T 11-11-2016 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TW_RS00800 e9b7dc01f988923555e14981f6695ea7 256 Gene3D G3DSA:1.10.287.70 13 82 2.1E-4 T 11-11-2016 TW_RS01480 4c69449ef2c1064228681b5206518a76 155 Pfam PF11292 Protein of unknown function (DUF3093) 4 148 5.3E-40 T 11-11-2016 IPR021443 Protein of unknown function DUF3093 TW_RS02590 1eae14f255e0d8dd50820ea52e28c99b 249 SUPERFAMILY SSF64005 19 243 2.22E-80 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TW_RS02590 1eae14f255e0d8dd50820ea52e28c99b 249 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 21 249 37.818 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TW_RS02590 1eae14f255e0d8dd50820ea52e28c99b 249 Pfam PF01255 Putative undecaprenyl diphosphate synthase 28 248 1.4E-72 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TW_RS02590 1eae14f255e0d8dd50820ea52e28c99b 249 Gene3D G3DSA:3.40.1180.10 16 249 1.3E-87 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TW_RS02590 1eae14f255e0d8dd50820ea52e28c99b 249 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 21 248 3.8E-75 T 11-11-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TW_RS02590 1eae14f255e0d8dd50820ea52e28c99b 249 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 194 211 - T 11-11-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 TW_RS04165 cf46b9430b912dc04027fbe4d212077d 202 Gene3D G3DSA:3.40.50.1240 3 185 1.5E-25 T 11-11-2016 IPR029033 Histidine phosphatase superfamily TW_RS04165 cf46b9430b912dc04027fbe4d212077d 202 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 185 1.7E-27 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 TW_RS04165 cf46b9430b912dc04027fbe4d212077d 202 SUPERFAMILY SSF53254 2 188 2.36E-32 T 11-11-2016 IPR029033 Histidine phosphatase superfamily TW_RS04165 cf46b9430b912dc04027fbe4d212077d 202 SMART SM00855 3 153 1.7E-8 T 11-11-2016 IPR013078 Histidine phosphatase superfamily, clade-1 TW_RS01720 27f6d88777172f3bd477dfa0c061397e 269 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 225 251 - T 11-11-2016 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981 TW_RS01720 27f6d88777172f3bd477dfa0c061397e 269 Pfam PF01148 Cytidylyltransferase family 19 261 1.9E-51 T 11-11-2016 TW_RS00020 1a95c40d6591b00b1f6aa579ee0433f0 144 Pfam PF05258 Protein of unknown function (DUF721) 40 121 1.5E-8 T 11-11-2016 IPR007922 Protein of unknown function DUF721/UPF0232 TW_RS03870 b50e961281c7431c449a97718e08510c 136 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 29 133 2.4E-27 T 11-11-2016 IPR021202 Helicase/secretion neighbourhood TadE-like protein TW_RS01970 78eb800f466cd386f61818bc1918d006 838 Pfam PF01433 Peptidase family M1 18 395 1.6E-71 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TW_RS01970 78eb800f466cd386f61818bc1918d006 838 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 836 0.0 T 11-11-2016 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 TW_RS01970 78eb800f466cd386f61818bc1918d006 838 SUPERFAMILY SSF55486 216 461 7.69E-77 T 11-11-2016 TW_RS01970 78eb800f466cd386f61818bc1918d006 838 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 303 318 2.0E-14 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TW_RS01970 78eb800f466cd386f61818bc1918d006 838 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 269 279 2.0E-14 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TW_RS01970 78eb800f466cd386f61818bc1918d006 838 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 130 145 2.0E-14 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TW_RS01970 78eb800f466cd386f61818bc1918d006 838 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 322 334 2.0E-14 T 11-11-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TW_RS01970 78eb800f466cd386f61818bc1918d006 838 SUPERFAMILY SSF63737 9 204 3.01E-34 T 11-11-2016 TW_RS01970 78eb800f466cd386f61818bc1918d006 838 Gene3D G3DSA:1.10.390.10 316 463 1.0E-41 T 11-11-2016 TW_RS01970 78eb800f466cd386f61818bc1918d006 838 Pfam PF11838 ERAP1-like C-terminal domain 527 826 1.5E-35 T 11-11-2016 IPR024571 ERAP1-like C-terminal domain TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 SUPERFAMILY SSF52317 1 188 2.07E-48 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 78 89 4.6E-13 T 11-11-2016 TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 4.6E-13 T 11-11-2016 TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 PRINTS PR00096 Glutamine amidotransferase superfamily signature 50 59 4.6E-13 T 11-11-2016 TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 Pfam PF00117 Glutamine amidotransferase class-I 6 186 1.6E-40 T 11-11-2016 IPR017926 Glutamine amidotransferase TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 PRINTS PR00097 Anthranilate synthase component II signature 50 59 1.5E-28 T 11-11-2016 TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 PRINTS PR00097 Anthranilate synthase component II signature 103 111 1.5E-28 T 11-11-2016 TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 PRINTS PR00097 Anthranilate synthase component II signature 123 135 1.5E-28 T 11-11-2016 TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 PRINTS PR00097 Anthranilate synthase component II signature 78 89 1.5E-28 T 11-11-2016 TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 PRINTS PR00097 Anthranilate synthase component II signature 166 179 1.5E-28 T 11-11-2016 TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 PRINTS PR00097 Anthranilate synthase component II signature 4 18 1.5E-28 T 11-11-2016 TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 Gene3D G3DSA:3.40.50.880 3 188 1.1E-53 T 11-11-2016 IPR029062 Class I glutamine amidotransferase-like TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 47 61 1.3E-8 T 11-11-2016 TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 78 94 1.3E-8 T 11-11-2016 TW_RS00065 47d96b9f71db6f8677ca4aa3b4eb8aa1 212 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 187 4.1E-48 T 11-11-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TW_RS02265 ec5c933485bbd1ecb0e87c8c5b229e36 293 Gene3D G3DSA:3.40.30.10 99 274 1.6E-20 T 11-11-2016 IPR012336 Thioredoxin-like fold TW_RS02265 ec5c933485bbd1ecb0e87c8c5b229e36 293 SUPERFAMILY SSF52833 96 274 2.76E-22 T 11-11-2016 IPR012336 Thioredoxin-like fold TW_RS02265 ec5c933485bbd1ecb0e87c8c5b229e36 293 Pfam PF13462 Thioredoxin 100 272 2.5E-20 T 11-11-2016 IPR012336 Thioredoxin-like fold TW_RS02090 7a65ea71e0db8f5456ce3f72716e5397 453 Pfam PF03993 Domain of Unknown Function (DUF349) 227 295 1.5E-9 T 11-11-2016 IPR007139 Protein of unknown function DUF349 TW_RS02090 7a65ea71e0db8f5456ce3f72716e5397 453 Pfam PF03993 Domain of Unknown Function (DUF349) 300 372 6.7E-9 T 11-11-2016 IPR007139 Protein of unknown function DUF349 TW_RS01640 d497e435cfe9d110041c9b255d441c8b 76 SUPERFAMILY SSF54814 13 60 7.19E-7 T 11-11-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 TW_RS01640 d497e435cfe9d110041c9b255d441c8b 76 Pfam PF13083 KH domain 7 61 1.4E-13 T 11-11-2016 TW_RS01640 d497e435cfe9d110041c9b255d441c8b 76 Gene3D G3DSA:3.30.1370.10 32 58 4.3E-6 T 11-11-2016 IPR004088 K Homology domain, type 1 GO:0003723 TW_RS02750 87a7eaa7cc69ece497be39f17d484a5b 339 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 249 336 2.9E-24 T 11-11-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TW_RS02750 87a7eaa7cc69ece497be39f17d484a5b 339 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 124 197 2.6E-21 T 11-11-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TW_RS02750 87a7eaa7cc69ece497be39f17d484a5b 339 SUPERFAMILY SSF53901 17 333 1.49E-50 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TW_RS02750 87a7eaa7cc69ece497be39f17d484a5b 339 Gene3D G3DSA:3.40.47.10 177 334 2.1E-33 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TW_RS02750 87a7eaa7cc69ece497be39f17d484a5b 339 Gene3D G3DSA:3.40.47.10 19 176 2.7E-48 T 11-11-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 Gene3D G3DSA:3.40.50.300 585 618 6.8E-31 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 Gene3D G3DSA:3.40.50.300 665 707 6.8E-31 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 Gene3D G3DSA:3.40.50.300 326 424 6.8E-31 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 Pfam PF13361 UvrD-like helicase C-terminal domain 322 692 1.3E-21 T 11-11-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 Pfam PF00580 UvrD/REP helicase N-terminal domain 21 315 7.8E-43 T 11-11-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 Gene3D G3DSA:1.10.486.10 425 564 6.1E-14 T 11-11-2016 TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 SUPERFAMILY SSF52980 794 933 1.07E-8 T 11-11-2016 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 Pfam PF12705 PD-(D/E)XK nuclease superfamily 804 961 2.8E-6 T 11-11-2016 TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 Gene3D G3DSA:3.40.50.300 218 317 3.8E-58 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 Gene3D G3DSA:3.40.50.300 19 167 3.8E-58 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 SUPERFAMILY SSF52540 18 174 2.5E-93 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 SUPERFAMILY SSF52540 208 639 2.5E-93 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01315 709d0e083495acac2a0b6cedfd2c6ff3 973 SUPERFAMILY SSF52540 669 709 2.5E-93 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00565 fc8b5559d8b926b14dd7a73cc52899a9 213 SUPERFAMILY SSF55811 14 185 4.06E-36 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TW_RS00565 fc8b5559d8b926b14dd7a73cc52899a9 213 Gene3D G3DSA:3.90.79.10 14 185 1.6E-41 T 11-11-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 TW_RS00565 fc8b5559d8b926b14dd7a73cc52899a9 213 Pfam PF00293 NUDIX domain 50 165 1.2E-16 T 11-11-2016 IPR000086 NUDIX hydrolase domain GO:0016787 TW_RS04430 c95934d3f1d6b25199dbcadf75fde198 112 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 48 62 - T 11-11-2016 IPR020539 Ribonuclease P, conserved site GO:0004526 TW_RS04430 c95934d3f1d6b25199dbcadf75fde198 112 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 4 108 1.1E-15 T 11-11-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TW_RS04430 c95934d3f1d6b25199dbcadf75fde198 112 SUPERFAMILY SSF54211 4 109 1.04E-20 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS04430 c95934d3f1d6b25199dbcadf75fde198 112 Pfam PF00825 Ribonuclease P 5 108 4.3E-21 T 11-11-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TW_RS04430 c95934d3f1d6b25199dbcadf75fde198 112 Gene3D G3DSA:3.30.230.10 5 110 5.2E-26 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TW_RS01910 b73ccc2727bdf1d856ad209b0bf1e825 515 SMART SM00382 296 511 2.6E-9 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS01910 b73ccc2727bdf1d856ad209b0bf1e825 515 SMART SM00382 41 225 1.7E-11 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS01910 b73ccc2727bdf1d856ad209b0bf1e825 515 Gene3D G3DSA:3.40.50.300 17 245 6.7E-45 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01910 b73ccc2727bdf1d856ad209b0bf1e825 515 Gene3D G3DSA:3.40.50.300 270 331 4.7E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01910 b73ccc2727bdf1d856ad209b0bf1e825 515 Gene3D G3DSA:3.40.50.300 371 513 4.7E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01910 b73ccc2727bdf1d856ad209b0bf1e825 515 Pfam PF00005 ABC transporter 33 170 5.8E-22 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS01910 b73ccc2727bdf1d856ad209b0bf1e825 515 Pfam PF00005 ABC transporter 288 462 4.1E-20 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS01910 b73ccc2727bdf1d856ad209b0bf1e825 515 SUPERFAMILY SSF52540 17 238 1.86E-40 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01910 b73ccc2727bdf1d856ad209b0bf1e825 515 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS01910 b73ccc2727bdf1d856ad209b0bf1e825 515 SUPERFAMILY SSF52540 404 513 1.25E-39 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01910 b73ccc2727bdf1d856ad209b0bf1e825 515 SUPERFAMILY SSF52540 267 362 1.25E-39 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00505 d555b07eeb816c21615a93c2ab8bd4cc 545 SUPERFAMILY SSF52540 23 343 1.45E-19 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00505 d555b07eeb816c21615a93c2ab8bd4cc 545 Pfam PF13175 AAA ATPase domain 23 125 2.6E-12 T 11-11-2016 TW_RS00505 d555b07eeb816c21615a93c2ab8bd4cc 545 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 265 323 4.3E-12 T 11-11-2016 IPR003959 ATPase, AAA-type, core GO:0005524 TW_RS00505 d555b07eeb816c21615a93c2ab8bd4cc 545 Gene3D G3DSA:3.40.50.300 23 340 3.3E-26 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04420 cc2da80a11bc7a7f2027f76fd8b220ac 310 Pfam PF02096 60Kd inner membrane protein 44 267 5.6E-49 T 11-11-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 TW_RS04420 cc2da80a11bc7a7f2027f76fd8b220ac 310 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 43 268 8.8E-56 T 11-11-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal TW_RS01120 3b9efa848a4ffbc3021b0b97f7bca2a9 260 SUPERFAMILY SSF52540 10 258 4.15E-66 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01120 3b9efa848a4ffbc3021b0b97f7bca2a9 260 Pfam PF00005 ABC transporter 27 187 4.0E-33 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS01120 3b9efa848a4ffbc3021b0b97f7bca2a9 260 Gene3D G3DSA:3.40.50.300 8 256 6.0E-70 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01120 3b9efa848a4ffbc3021b0b97f7bca2a9 260 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 236 258 4.7E-11 T 11-11-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TW_RS01120 3b9efa848a4ffbc3021b0b97f7bca2a9 260 SMART SM00382 36 244 1.4E-7 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS04385 62b306526be3f304f6c581f305996795 244 Pfam PF02585 GlcNAc-PI de-N-acetylase 15 163 6.5E-28 T 11-11-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TW_RS04385 62b306526be3f304f6c581f305996795 244 Gene3D G3DSA:3.40.50.10320 12 232 2.1E-47 T 11-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 TW_RS04385 62b306526be3f304f6c581f305996795 244 SUPERFAMILY SSF102588 12 217 4.97E-46 T 11-11-2016 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 TW_RS02050 9638b359a385ce8f7a7d00d323bc8d56 575 Pfam PF09949 Uncharacterized conserved protein (DUF2183) 429 525 5.0E-30 T 11-11-2016 IPR019236 Domain of unknown function DUF2183 TW_RS02050 9638b359a385ce8f7a7d00d323bc8d56 575 Pfam PF09335 SNARE associated Golgi protein 41 159 3.6E-21 T 11-11-2016 IPR032816 SNARE associated Golgi protein TW_RS04400 fe96ae45fa3834a76e5c925f0bc917ba 298 Pfam PF02195 ParB-like nuclease domain 44 131 1.6E-23 T 11-11-2016 IPR003115 ParB/Sulfiredoxin TW_RS04400 fe96ae45fa3834a76e5c925f0bc917ba 298 SMART SM00470 42 131 7.6E-32 T 11-11-2016 IPR003115 ParB/Sulfiredoxin TW_RS04400 fe96ae45fa3834a76e5c925f0bc917ba 298 SUPERFAMILY SSF110849 42 133 1.02E-27 T 11-11-2016 IPR003115 ParB/Sulfiredoxin TW_RS04400 fe96ae45fa3834a76e5c925f0bc917ba 298 SUPERFAMILY SSF109709 124 231 1.05E-31 T 11-11-2016 TW_RS04400 fe96ae45fa3834a76e5c925f0bc917ba 298 Gene3D G3DSA:3.90.1530.10 40 137 6.0E-35 T 11-11-2016 TW_RS04400 fe96ae45fa3834a76e5c925f0bc917ba 298 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 39 216 5.2E-57 T 11-11-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TW_RS02075 b70bf4ffde551dedfdef3bccc36abf55 278 SUPERFAMILY SSF56281 29 275 9.07E-29 T 11-11-2016 IPR001279 Metallo-beta-lactamase TW_RS02075 b70bf4ffde551dedfdef3bccc36abf55 278 Gene3D G3DSA:3.60.15.10 30 252 8.0E-22 T 11-11-2016 IPR001279 Metallo-beta-lactamase TW_RS00175 f16e05feec8198f376b600550255d5fa 292 SUPERFAMILY SSF53448 2 285 3.38E-81 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS00175 f16e05feec8198f376b600550255d5fa 292 Pfam PF00483 Nucleotidyl transferase 2 235 7.9E-63 T 11-11-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TW_RS00175 f16e05feec8198f376b600550255d5fa 292 Gene3D G3DSA:3.90.550.10 2 263 7.0E-62 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS00175 f16e05feec8198f376b600550255d5fa 292 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 285 2.4E-135 T 11-11-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 TW_RS04485 c236e18b59295cd74617ccfe337f229e 201 SUPERFAMILY SSF81296 24 117 8.4E-15 T 11-11-2016 IPR014756 Immunoglobulin E-set TW_RS04485 c236e18b59295cd74617ccfe337f229e 201 Gene3D G3DSA:2.60.40.1220 24 117 2.5E-14 T 11-11-2016 IPR014755 Copper resistance protein CopC/internalin, immunoglobulin-like TW_RS04485 c236e18b59295cd74617ccfe337f229e 201 Pfam PF04234 CopC domain 25 117 2.9E-16 T 11-11-2016 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 TW_RS00085 ff7700efb57480fc55b1428a2e0735cb 427 SUPERFAMILY SSF49313 62 133 5.96E-5 T 11-11-2016 IPR015919 Cadherin-like GO:0005509|GO:0016020 TW_RS00085 ff7700efb57480fc55b1428a2e0735cb 427 Pfam PF05345 Putative Ig domain 71 122 6.6E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS00085 ff7700efb57480fc55b1428a2e0735cb 427 Pfam PF05345 Putative Ig domain 173 212 1.1E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS00085 ff7700efb57480fc55b1428a2e0735cb 427 Pfam PF05345 Putative Ig domain 361 398 9.0E-10 T 11-11-2016 IPR008009 Putative Ig TW_RS01715 369114209c7edfe36f3267afda5fef96 178 Pfam PF01765 Ribosome recycling factor 17 176 1.3E-40 T 11-11-2016 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 TW_RS01715 369114209c7edfe36f3267afda5fef96 178 SUPERFAMILY SSF55194 4 177 5.63E-48 T 11-11-2016 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 TW_RS01715 369114209c7edfe36f3267afda5fef96 178 Gene3D G3DSA:1.10.132.20 63 177 1.2E-25 T 11-11-2016 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 TW_RS00160 b2417b6e710ee766f2266c1ddad0873c 275 Pfam PF04321 RmlD substrate binding domain 12 263 5.2E-85 T 11-11-2016 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581 TW_RS00160 b2417b6e710ee766f2266c1ddad0873c 275 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 262 6.7E-79 T 11-11-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581 TW_RS00160 b2417b6e710ee766f2266c1ddad0873c 275 SUPERFAMILY SSF51735 1 263 8.07E-75 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00160 b2417b6e710ee766f2266c1ddad0873c 275 Gene3D G3DSA:3.40.50.720 14 212 3.4E-48 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00310 7159436cbf69c4d6381b35cdde7d77c3 331 Gene3D G3DSA:3.40.50.1980 180 321 6.8E-11 T 11-11-2016 TW_RS00310 7159436cbf69c4d6381b35cdde7d77c3 331 Pfam PF01497 Periplasmic binding protein 107 294 1.5E-15 T 11-11-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 TW_RS00310 7159436cbf69c4d6381b35cdde7d77c3 331 Gene3D G3DSA:3.40.50.1980 53 179 1.5E-20 T 11-11-2016 TW_RS00310 7159436cbf69c4d6381b35cdde7d77c3 331 SUPERFAMILY SSF53807 53 321 2.59E-37 T 11-11-2016 TW_RS02960 9b2f60d15cba86e71f9eb6635f8c58ac 800 Pfam PF07861 WisP family N-Terminal Region 92 335 1.1E-14 T 11-11-2016 IPR012503 WisP, N-terminal TW_RS02960 9b2f60d15cba86e71f9eb6635f8c58ac 800 Pfam PF05345 Putative Ig domain 749 787 7.6E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS02960 9b2f60d15cba86e71f9eb6635f8c58ac 800 Pfam PF05345 Putative Ig domain 638 681 5.6E-12 T 11-11-2016 IPR008009 Putative Ig TW_RS02960 9b2f60d15cba86e71f9eb6635f8c58ac 800 Pfam PF05345 Putative Ig domain 528 570 7.2E-7 T 11-11-2016 IPR008009 Putative Ig TW_RS02960 9b2f60d15cba86e71f9eb6635f8c58ac 800 Pfam PF05345 Putative Ig domain 417 460 5.6E-12 T 11-11-2016 IPR008009 Putative Ig TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 Gene3D G3DSA:3.40.50.1980 37 195 7.6E-45 T 11-11-2016 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 PRINTS PR00690 Adhesin family signature 48 66 2.6E-26 T 11-11-2016 IPR006128 Adhesion lipoprotein GO:0007155 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 PRINTS PR00690 Adhesin family signature 203 224 2.6E-26 T 11-11-2016 IPR006128 Adhesion lipoprotein GO:0007155 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 PRINTS PR00690 Adhesin family signature 79 92 2.6E-26 T 11-11-2016 IPR006128 Adhesion lipoprotein GO:0007155 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 PRINTS PR00690 Adhesin family signature 92 109 2.6E-26 T 11-11-2016 IPR006128 Adhesion lipoprotein GO:0007155 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 PRINTS PR00690 Adhesin family signature 256 274 2.6E-26 T 11-11-2016 IPR006128 Adhesion lipoprotein GO:0007155 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 PRINTS PR00690 Adhesin family signature 284 303 2.6E-26 T 11-11-2016 IPR006128 Adhesion lipoprotein GO:0007155 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 PRINTS PR00691 Adhesin B signature 92 111 3.6E-23 T 11-11-2016 IPR006129 Adhesin B GO:0007155 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 PRINTS PR00691 Adhesin B signature 203 220 3.6E-23 T 11-11-2016 IPR006129 Adhesin B GO:0007155 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 PRINTS PR00691 Adhesin B signature 229 247 3.6E-23 T 11-11-2016 IPR006129 Adhesin B GO:0007155 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 PRINTS PR00691 Adhesin B signature 252 269 3.6E-23 T 11-11-2016 IPR006129 Adhesin B GO:0007155 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 PRINTS PR00691 Adhesin B signature 73 91 3.6E-23 T 11-11-2016 IPR006129 Adhesin B GO:0007155 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 PRINTS PR00691 Adhesin B signature 48 69 3.6E-23 T 11-11-2016 IPR006129 Adhesin B GO:0007155 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 SUPERFAMILY SSF53807 48 319 6.87E-68 T 11-11-2016 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 Gene3D G3DSA:3.40.50.1980 196 319 2.2E-28 T 11-11-2016 TW_RS03705 79720f9ea032c8484cde98ab692f458a 322 Pfam PF01297 Zinc-uptake complex component A periplasmic 51 316 1.3E-60 T 11-11-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TW_RS03170 8dd7c9199b7d3d7f4431fffc9e97f03b 294 Pfam PF00482 Type II secretion system (T2SS), protein F 123 247 2.3E-8 T 11-11-2016 IPR018076 Type II secretion system F domain TW_RS01885 261aaddd9fc9ef579c961b3923e18448 100 SUPERFAMILY SSF141000 2 90 4.32E-8 T 11-11-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TW_RS01485 3474b4073ca79e73e6e843d7e0f7376e 146 Pfam PF00692 dUTPase 13 140 6.2E-34 T 11-11-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 TW_RS01485 3474b4073ca79e73e6e843d7e0f7376e 146 SUPERFAMILY SSF51283 6 141 6.67E-43 T 11-11-2016 IPR029054 dUTPase-like TW_RS01485 3474b4073ca79e73e6e843d7e0f7376e 146 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 3 141 28.634 T 11-11-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 TW_RS01485 3474b4073ca79e73e6e843d7e0f7376e 146 TIGRFAM TIGR00576 dut: dUTP diphosphatase 9 141 2.0E-44 T 11-11-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|Reactome: R-HSA-500753 TW_RS01485 3474b4073ca79e73e6e843d7e0f7376e 146 Gene3D G3DSA:2.70.40.10 6 141 3.2E-49 T 11-11-2016 IPR029054 dUTPase-like TW_RS00870 6d459e6d5fd85f1a4050034525f83c1d 409 Pfam PF08544 GHMP kinases C terminal 320 389 4.1E-7 T 11-11-2016 IPR013750 GHMP kinase, C-terminal domain TW_RS00870 6d459e6d5fd85f1a4050034525f83c1d 409 SUPERFAMILY SSF55060 270 394 9.21E-20 T 11-11-2016 IPR013750 GHMP kinase, C-terminal domain TW_RS00870 6d459e6d5fd85f1a4050034525f83c1d 409 SUPERFAMILY SSF54211 157 264 1.29E-22 T 11-11-2016 IPR020568 Ribosomal protein S5 domain 2-type fold TW_RS00870 6d459e6d5fd85f1a4050034525f83c1d 409 Pfam PF00288 GHMP kinases N terminal domain 193 251 9.2E-8 T 11-11-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 TW_RS00870 6d459e6d5fd85f1a4050034525f83c1d 409 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 90 399 20.696 T 11-11-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TW_RS00870 6d459e6d5fd85f1a4050034525f83c1d 409 Gene3D G3DSA:3.30.230.10 142 265 9.5E-36 T 11-11-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TW_RS00870 6d459e6d5fd85f1a4050034525f83c1d 409 Gene3D G3DSA:3.30.70.890 269 394 8.7E-20 T 11-11-2016 IPR013750 GHMP kinase, C-terminal domain TW_RS02110 190a1696b79fbb6fb63e4cad714ab34b 145 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 11 133 1.8E-18 T 11-11-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TW_RS02110 190a1696b79fbb6fb63e4cad714ab34b 145 Pfam PF03652 Holliday junction resolvase 10 133 5.7E-28 T 11-11-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TW_RS02110 190a1696b79fbb6fb63e4cad714ab34b 145 SMART SM00732 8 101 1.6E-13 T 11-11-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 TW_RS02110 190a1696b79fbb6fb63e4cad714ab34b 145 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 8 136 17.565 T 11-11-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TW_RS02110 190a1696b79fbb6fb63e4cad714ab34b 145 SUPERFAMILY SSF53098 9 134 8.65E-25 T 11-11-2016 IPR012337 Ribonuclease H-like domain GO:0003676 TW_RS02110 190a1696b79fbb6fb63e4cad714ab34b 145 Gene3D G3DSA:3.30.420.140 10 135 4.5E-29 T 11-11-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 TW_RS03470 3b3943144170a0ba3674cd0e81c0bdb9 217 Pfam PF09335 SNARE associated Golgi protein 45 170 5.8E-16 T 11-11-2016 IPR032816 SNARE associated Golgi protein TW_RS03335 1dc05187f7608792a87e4065a7eec7c6 848 Gene3D G3DSA:3.90.550.10 134 226 5.0E-8 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS03335 1dc05187f7608792a87e4065a7eec7c6 848 Gene3D G3DSA:3.90.550.10 57 102 5.0E-8 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS03335 1dc05187f7608792a87e4065a7eec7c6 848 SUPERFAMILY SSF53448 6 114 5.4E-12 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS03335 1dc05187f7608792a87e4065a7eec7c6 848 SUPERFAMILY SSF53448 168 226 5.4E-12 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS03335 1dc05187f7608792a87e4065a7eec7c6 848 Pfam PF00534 Glycosyl transferases group 1 594 767 2.8E-10 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 TW_RS03335 1dc05187f7608792a87e4065a7eec7c6 848 SUPERFAMILY SSF53756 398 785 4.96E-19 T 11-11-2016 TW_RS03840 1f0b7f4e8d03ff3cfdbee83a554e031b 203 SUPERFAMILY SSF52499 11 199 2.35E-35 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 TW_RS03840 1f0b7f4e8d03ff3cfdbee83a554e031b 203 Gene3D G3DSA:3.40.50.850 13 200 3.9E-41 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 TW_RS03840 1f0b7f4e8d03ff3cfdbee83a554e031b 203 Pfam PF00857 Isochorismatase family 15 198 3.1E-24 T 11-11-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 TW_RS01115 cabf2d5e3fa763eb045cf1d8988d51de 364 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 323 3.5E-42 T 11-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TW_RS01320 0678768be743dd8b0374b63c52e0b3b1 420 SUPERFAMILY SSF56112 69 281 2.02E-7 T 11-11-2016 IPR011009 Protein kinase-like domain TW_RS01320 0678768be743dd8b0374b63c52e0b3b1 420 Gene3D G3DSA:3.90.1200.10 150 304 5.6E-5 T 11-11-2016 TW_RS01680 563f72305252c2d46e302c407f886c36 399 Gene3D G3DSA:3.40.50.450 151 293 8.4E-8 T 11-11-2016 TW_RS01680 563f72305252c2d46e302c407f886c36 399 Pfam PF02481 DNA recombination-mediator protein A 128 315 3.0E-61 T 11-11-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 TW_RS01680 563f72305252c2d46e302c407f886c36 399 SUPERFAMILY SSF102405 127 320 8.61E-26 T 11-11-2016 TW_RS01680 563f72305252c2d46e302c407f886c36 399 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 128 321 7.0E-59 T 11-11-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 TW_RS00275 5a4b9fbbbd373cc13bc8ab194395387d 378 SUPERFAMILY SSF51735 3 137 6.02E-22 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00275 5a4b9fbbbd373cc13bc8ab194395387d 378 SUPERFAMILY SSF55021 312 373 8.59E-8 T 11-11-2016 TW_RS00275 5a4b9fbbbd373cc13bc8ab194395387d 378 Gene3D G3DSA:3.30.70.260 314 361 4.3E-5 T 11-11-2016 TW_RS00275 5a4b9fbbbd373cc13bc8ab194395387d 378 Gene3D G3DSA:3.40.50.720 3 120 3.7E-19 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00275 5a4b9fbbbd373cc13bc8ab194395387d 378 Gene3D G3DSA:3.40.50.720 155 198 3.7E-19 T 11-11-2016 IPR016040 NAD(P)-binding domain TW_RS00275 5a4b9fbbbd373cc13bc8ab194395387d 378 SUPERFAMILY SSF48179 193 283 2.38E-22 T 11-11-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 TW_RS00275 5a4b9fbbbd373cc13bc8ab194395387d 378 Pfam PF02153 Prephenate dehydrogenase 161 282 1.1E-18 T 11-11-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 TW_RS00275 5a4b9fbbbd373cc13bc8ab194395387d 378 Pfam PF02153 Prephenate dehydrogenase 19 139 5.8E-15 T 11-11-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 TW_RS03895 3e383ecb966826c966e3b667bc9d1ff5 152 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 150 2.7E-27 T 11-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like TW_RS03895 3e383ecb966826c966e3b667bc9d1ff5 152 SUPERFAMILY SSF55298 1 149 2.67E-46 T 11-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like TW_RS03895 3e383ecb966826c966e3b667bc9d1ff5 152 Gene3D G3DSA:3.30.1330.40 2 150 1.5E-54 T 11-11-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like TW_RS02815 0ab1a04327ea7f1f065088ca6485d9a9 173 Pfam PF11241 Protein of unknown function (DUF3043) 3 165 8.7E-47 T 11-11-2016 IPR021403 Protein of unknown function DUF3043 TW_RS01145 ba0b9b7c78c12ad20a39ea9d58f8fc20 248 Pfam PF00573 Ribosomal protein L4/L1 family 20 200 6.9E-57 T 11-11-2016 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 TW_RS01145 ba0b9b7c78c12ad20a39ea9d58f8fc20 248 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 10 207 30.265 T 11-11-2016 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01145 ba0b9b7c78c12ad20a39ea9d58f8fc20 248 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 20 201 1.1E-61 T 11-11-2016 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TW_RS01145 ba0b9b7c78c12ad20a39ea9d58f8fc20 248 SUPERFAMILY SSF52166 5 203 2.62E-65 T 11-11-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 TW_RS01145 ba0b9b7c78c12ad20a39ea9d58f8fc20 248 Gene3D G3DSA:3.40.1370.10 59 200 8.8E-43 T 11-11-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 TW_RS00560 236324d15993aa69061b523028b966d2 160 Pfam PF07860 WisP family C-Terminal Region 53 101 3.6E-23 T 11-11-2016 IPR012421 WisP, C-terminal TW_RS01470 732ad36d6aba8897b3c8e7ebb45f4114 320 Pfam PF11268 Protein of unknown function (DUF3071) 14 169 3.6E-30 T 11-11-2016 IPR021421 Protein of unknown function DUF3071 TW_RS02930 eb048d3a502b6152d928e7d71fd92d12 113 Pfam PF11239 Protein of unknown function (DUF3040) 16 93 3.8E-18 T 11-11-2016 IPR021401 Protein of unknown function DUF3040 TW_RS01110 d89c1afe46f14e5c8cd4cfae8d065db6 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 315 2.2E-46 T 11-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TW_RS00785 808450c34890886ddf41537ca730c143 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 133 316 3.0E-29 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TW_RS00785 808450c34890886ddf41537ca730c143 321 Gene3D G3DSA:1.10.3720.10 108 313 5.7E-25 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TW_RS00785 808450c34890886ddf41537ca730c143 321 SUPERFAMILY SSF161098 110 299 6.02E-23 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TW_RS01905 5c944ee640c8219de41c99efeaac7e87 201 PIRSF PIRSF037394 13 201 4.4E-56 T 11-11-2016 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted TW_RS01905 5c944ee640c8219de41c99efeaac7e87 201 Pfam PF09819 ABC-type cobalt transport system, permease component 23 141 1.1E-29 T 11-11-2016 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted TW_RS03570 174b225cc85d715e1fb1bfea54339f6c 428 SUPERFAMILY SSF53383 6 422 5.75E-157 T 11-11-2016 IPR015424 Pyridoxal phosphate-dependent transferase TW_RS03570 174b225cc85d715e1fb1bfea54339f6c 428 Pfam PF00464 Serine hydroxymethyltransferase 15 396 8.5E-146 T 11-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TW_RS03570 174b225cc85d715e1fb1bfea54339f6c 428 Gene3D G3DSA:3.40.640.10 43 288 1.1E-97 T 11-11-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 TW_RS03570 174b225cc85d715e1fb1bfea54339f6c 428 PIRSF PIRSF000412 4 425 1.1E-142 T 11-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TW_RS03570 174b225cc85d715e1fb1bfea54339f6c 428 Gene3D G3DSA:3.90.1150.10 289 410 4.5E-37 T 11-11-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 TW_RS03570 174b225cc85d715e1fb1bfea54339f6c 428 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 13 423 47.1 T 11-11-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TW_RS03570 174b225cc85d715e1fb1bfea54339f6c 428 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 228 244 - T 11-11-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TW_RS01205 ef361454a69bffacb37747c462476cdd 132 SUPERFAMILY SSF56047 3 132 1.7E-43 T 11-11-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01205 ef361454a69bffacb37747c462476cdd 132 Gene3D G3DSA:3.30.1490.10 76 132 8.6E-26 T 11-11-2016 TW_RS01205 ef361454a69bffacb37747c462476cdd 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 11-11-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01205 ef361454a69bffacb37747c462476cdd 132 Gene3D G3DSA:3.30.1370.30 2 72 2.7E-27 T 11-11-2016 TW_RS01205 ef361454a69bffacb37747c462476cdd 132 Pfam PF00410 Ribosomal protein S8 5 132 6.3E-45 T 11-11-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01205 ef361454a69bffacb37747c462476cdd 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 29.944 T 11-11-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS04415 8e10c8dc225aefbe25cb39acf977425d 166 Gene3D G3DSA:3.30.1370.50 128 164 3.6E-12 T 11-11-2016 IPR001374 R3H domain GO:0003676 TW_RS04415 8e10c8dc225aefbe25cb39acf977425d 166 SMART SM00393 88 166 6.4E-8 T 11-11-2016 IPR001374 R3H domain GO:0003676 TW_RS04415 8e10c8dc225aefbe25cb39acf977425d 166 SUPERFAMILY SSF82708 126 165 2.55E-10 T 11-11-2016 IPR001374 R3H domain GO:0003676 TW_RS04415 8e10c8dc225aefbe25cb39acf977425d 166 Pfam PF01424 R3H domain 125 164 1.3E-13 T 11-11-2016 IPR001374 R3H domain GO:0003676 TW_RS03180 ba37fba6a5204b9c85389b7d7fd27574 171 Pfam PF05345 Putative Ig domain 87 139 1.2E-12 T 11-11-2016 IPR008009 Putative Ig TW_RS04295 438d618ccb25bc5356a37a2df730900d 167 Pfam PF04417 Protein of unknown function (DUF501) 37 155 9.0E-34 T 11-11-2016 IPR007511 Protein of unknown function DUF501 TW_RS02785 c2afd9cf16681a09fa5731272a230459 207 SUPERFAMILY SSF81452 9 206 3.01E-50 T 11-11-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02785 c2afd9cf16681a09fa5731272a230459 207 Gene3D G3DSA:1.20.120.80 17 206 7.8E-50 T 11-11-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS02785 c2afd9cf16681a09fa5731272a230459 207 Pfam PF00510 Cytochrome c oxidase subunit III 11 206 3.4E-23 T 11-11-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS03050 39494b4efb5305b734ea24fe72872184 418 SUPERFAMILY SSF53335 224 404 4.82E-42 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS03050 39494b4efb5305b734ea24fe72872184 418 SUPERFAMILY SSF53335 22 79 4.82E-42 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS03050 39494b4efb5305b734ea24fe72872184 418 SMART SM00650 30 342 3.3E-40 T 11-11-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TW_RS03050 39494b4efb5305b734ea24fe72872184 418 Gene3D G3DSA:1.10.8.100 351 404 1.2E-15 T 11-11-2016 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201 TW_RS03050 39494b4efb5305b734ea24fe72872184 418 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 11-11-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TW_RS03050 39494b4efb5305b734ea24fe72872184 418 Pfam PF00398 Ribosomal RNA adenine dimethylase 227 404 2.7E-22 T 11-11-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TW_RS03050 39494b4efb5305b734ea24fe72872184 418 Pfam PF00398 Ribosomal RNA adenine dimethylase 18 82 2.1E-13 T 11-11-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TW_RS03050 39494b4efb5305b734ea24fe72872184 418 Gene3D G3DSA:3.40.50.150 221 340 4.3E-81 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS03050 39494b4efb5305b734ea24fe72872184 418 Gene3D G3DSA:3.40.50.150 13 76 4.3E-81 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS04490 ac5b142f9c1755eebc1da9a52ab868bb 482 Pfam PF05345 Putative Ig domain 365 413 3.0E-9 T 11-11-2016 IPR008009 Putative Ig TW_RS02615 1dce37dbb5ffd951e72903693ae6ce6b 235 PIRSF PIRSF015601 1 235 9.8E-53 T 11-11-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TW_RS02615 1dce37dbb5ffd951e72903693ae6ce6b 235 SUPERFAMILY SSF88697 4 59 2.73E-5 T 11-11-2016 IPR015947 PUA-like domain TW_RS02615 1dce37dbb5ffd951e72903693ae6ce6b 235 SUPERFAMILY SSF75217 77 235 9.16E-33 T 11-11-2016 IPR029028 Alpha/beta knot methyltransferases TW_RS02615 1dce37dbb5ffd951e72903693ae6ce6b 235 Pfam PF04452 RNA methyltransferase 19 229 3.6E-48 T 11-11-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TW_RS02615 1dce37dbb5ffd951e72903693ae6ce6b 235 Gene3D G3DSA:3.40.1280.10 2 235 4.5E-49 T 11-11-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TW_RS02615 1dce37dbb5ffd951e72903693ae6ce6b 235 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 15 233 3.1E-28 T 11-11-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 TW_RS01820 10ba471078c5985c4be8fda20bfd4d9d 542 Gene3D G3DSA:3.40.50.300 102 384 1.0E-108 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01820 10ba471078c5985c4be8fda20bfd4d9d 542 SUPERFAMILY SSF52540 103 383 1.78E-94 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01820 10ba471078c5985c4be8fda20bfd4d9d 542 SUPERFAMILY SSF50615 29 101 4.58E-20 T 11-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01820 10ba471078c5985c4be8fda20bfd4d9d 542 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 35 99 5.6E-15 T 11-11-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01820 10ba471078c5985c4be8fda20bfd4d9d 542 SUPERFAMILY SSF47917 385 511 9.42E-41 T 11-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01820 10ba471078c5985c4be8fda20bfd4d9d 542 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 8 511 1.1E-231 T 11-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 TW_RS01820 10ba471078c5985c4be8fda20bfd4d9d 542 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 5 513 46.888 T 11-11-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 TW_RS01820 10ba471078c5985c4be8fda20bfd4d9d 542 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 384 508 4.9E-41 T 11-11-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01820 10ba471078c5985c4be8fda20bfd4d9d 542 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 368 377 - T 11-11-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01820 10ba471078c5985c4be8fda20bfd4d9d 542 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 156 377 3.7E-69 T 11-11-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 TW_RS01820 10ba471078c5985c4be8fda20bfd4d9d 542 Gene3D G3DSA:2.40.30.20 34 100 2.1E-22 T 11-11-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210 TW_RS01820 10ba471078c5985c4be8fda20bfd4d9d 542 Gene3D G3DSA:1.20.150.20 385 511 8.8E-45 T 11-11-2016 TW_RS00975 ee2b37fc7f4904ea3a1a2dd8ab443c85 167 Pfam PF00156 Phosphoribosyl transferase domain 12 152 3.8E-22 T 11-11-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 TW_RS00975 ee2b37fc7f4904ea3a1a2dd8ab443c85 167 SUPERFAMILY SSF53271 2 166 7.6E-46 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like TW_RS00975 ee2b37fc7f4904ea3a1a2dd8ab443c85 167 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 4 166 5.5E-57 T 11-11-2016 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 TW_RS00975 ee2b37fc7f4904ea3a1a2dd8ab443c85 167 Gene3D G3DSA:3.40.50.2020 2 166 2.9E-65 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like TW_RS03645 7c2c62fc31fed3075888c73b9b253233 330 Gene3D G3DSA:3.20.20.140 6 329 1.0E-89 T 11-11-2016 TW_RS03645 7c2c62fc31fed3075888c73b9b253233 330 SUPERFAMILY SSF51556 6 327 9.95E-75 T 11-11-2016 IPR032466 Metal-dependent hydrolase TW_RS03645 7c2c62fc31fed3075888c73b9b253233 330 Pfam PF02126 Phosphotriesterase family 15 327 7.5E-44 T 11-11-2016 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 TW_RS03645 7c2c62fc31fed3075888c73b9b253233 330 PIRSF PIRSF016839 5 330 1.8E-107 T 11-11-2016 TW_RS03175 fe3825907e8d2693a84870d211a30472 444 SUPERFAMILY SSF52540 88 405 5.03E-42 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03175 fe3825907e8d2693a84870d211a30472 444 Gene3D G3DSA:3.30.450.90 102 198 1.9E-25 T 11-11-2016 TW_RS03175 fe3825907e8d2693a84870d211a30472 444 Pfam PF00437 Type II/IV secretion system protein 106 377 2.3E-57 T 11-11-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 TW_RS03175 fe3825907e8d2693a84870d211a30472 444 Gene3D G3DSA:3.40.50.300 206 404 3.6E-43 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00015 f05d0a05edf03b08e7f72243dcbd5d37 363 ProSitePatterns PS00617 RecF protein signature 1. 119 139 - T 11-11-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 TW_RS00015 f05d0a05edf03b08e7f72243dcbd5d37 363 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 6 342 9.9E-87 T 11-11-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TW_RS00015 f05d0a05edf03b08e7f72243dcbd5d37 363 ProSitePatterns PS00618 RecF protein signature 2. 304 322 - T 11-11-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 TW_RS00015 f05d0a05edf03b08e7f72243dcbd5d37 363 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 363 77.747 T 11-11-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TW_RS00015 f05d0a05edf03b08e7f72243dcbd5d37 363 SUPERFAMILY SSF52540 6 355 1.12E-42 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00015 f05d0a05edf03b08e7f72243dcbd5d37 363 Gene3D G3DSA:3.40.50.300 6 173 1.8E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00015 f05d0a05edf03b08e7f72243dcbd5d37 363 Gene3D G3DSA:3.40.50.300 233 340 1.8E-44 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00015 f05d0a05edf03b08e7f72243dcbd5d37 363 Pfam PF02463 RecF/RecN/SMC N terminal domain 6 340 4.7E-21 T 11-11-2016 IPR003395 RecF/RecN/SMC, N-terminal TW_RS04075 c48aa656b4e78622c03a8fab5b911378 416 Gene3D G3DSA:3.30.390.10 135 163 1.3E-30 T 11-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04075 c48aa656b4e78622c03a8fab5b911378 416 Gene3D G3DSA:3.30.390.10 27 92 1.3E-30 T 11-11-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TW_RS04075 c48aa656b4e78622c03a8fab5b911378 416 SUPERFAMILY SSF51604 133 377 3.67E-34 T 11-11-2016 IPR029065 Enolase C-terminal domain-like TW_RS04075 c48aa656b4e78622c03a8fab5b911378 416 SMART SM00922 146 244 8.0E-9 T 11-11-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TW_RS04075 c48aa656b4e78622c03a8fab5b911378 416 Gene3D G3DSA:3.20.20.120 164 405 4.5E-49 T 11-11-2016 IPR029065 Enolase C-terminal domain-like TW_RS04075 c48aa656b4e78622c03a8fab5b911378 416 Pfam PF13378 Enolase C-terminal domain-like 157 258 2.2E-12 T 11-11-2016 IPR029065 Enolase C-terminal domain-like TW_RS02465 2358ee72c231b35fbb6bab4b1682ae03 272 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 11 263 2.3E-35 T 11-11-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 TW_RS02465 2358ee72c231b35fbb6bab4b1682ae03 272 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 264 14.555 T 11-11-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 TW_RS02465 2358ee72c231b35fbb6bab4b1682ae03 272 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 13 257 5.1E-47 T 11-11-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 TW_RS00745 d899051aee0f54282f55b1f4005f98bc 260 SUPERFAMILY SSF52540 1 257 2.56E-25 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00745 d899051aee0f54282f55b1f4005f98bc 260 Gene3D G3DSA:3.40.50.300 1 257 8.6E-26 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00745 d899051aee0f54282f55b1f4005f98bc 260 Pfam PF13614 AAA domain 2 133 2.7E-9 T 11-11-2016 IPR025669 AAA domain TW_RS02835 a61d6ff5294d6682cc8832d13ae5400e 158 SUPERFAMILY SSF46955 19 100 2.2E-14 T 11-11-2016 IPR009061 Putative DNA-binding domain TW_RS02835 a61d6ff5294d6682cc8832d13ae5400e 158 Gene3D G3DSA:1.10.1660.10 19 89 1.1E-13 T 11-11-2016 TW_RS02835 a61d6ff5294d6682cc8832d13ae5400e 158 SMART SM00422 14 86 6.8E-15 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TW_RS02835 a61d6ff5294d6682cc8832d13ae5400e 158 Pfam PF13411 MerR HTH family regulatory protein 19 84 1.7E-14 T 11-11-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TW_RS02925 5166be829ea1f653269c14a30a3cf689 156 Pfam PF05345 Putative Ig domain 30 79 4.9E-9 T 11-11-2016 IPR008009 Putative Ig TW_RS04480 8959c11ba36581dc96a0ceb695ff0697 482 Pfam PF05345 Putative Ig domain 365 413 3.0E-9 T 11-11-2016 IPR008009 Putative Ig TW_RS02450 95ff8c4edc645b1af34ead9b8a0d5265 391 Pfam PF13439 Glycosyltransferase Family 4 20 201 1.5E-23 T 11-11-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TW_RS02450 95ff8c4edc645b1af34ead9b8a0d5265 391 Pfam PF00534 Glycosyl transferases group 1 208 352 4.5E-34 T 11-11-2016 IPR001296 Glycosyl transferase, family 1 TW_RS02450 95ff8c4edc645b1af34ead9b8a0d5265 391 SUPERFAMILY SSF53756 9 384 1.72E-78 T 11-11-2016 TW_RS02450 95ff8c4edc645b1af34ead9b8a0d5265 391 Gene3D G3DSA:3.40.50.2000 210 363 3.2E-33 T 11-11-2016 TW_RS00295 62a80827f3562b190186ee1d344c222e 338 Pfam PF00348 Polyprenyl synthetase 42 261 3.6E-47 T 11-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 TW_RS00295 62a80827f3562b190186ee1d344c222e 338 SUPERFAMILY SSF48576 13 337 3.93E-72 T 11-11-2016 IPR008949 Isoprenoid synthase domain TW_RS00295 62a80827f3562b190186ee1d344c222e 338 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 11-11-2016 IPR000092 Polyprenyl synthetase GO:0008299 TW_RS00295 62a80827f3562b190186ee1d344c222e 338 Gene3D G3DSA:1.10.600.10 22 337 1.6E-75 T 11-11-2016 IPR008949 Isoprenoid synthase domain TW_RS02965 458316e1fa5a973f70589f7c161e6679 187 Pfam PF02632 BioY family 37 182 3.4E-31 T 11-11-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TW_RS02965 458316e1fa5a973f70589f7c161e6679 187 PIRSF PIRSF016661 3 187 6.0E-37 T 11-11-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TW_RS00340 5d92ca5f5966f78960f58ef2887b64a8 97 Gene3D G3DSA:1.10.10.10 4 96 4.5E-30 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS00340 5d92ca5f5966f78960f58ef2887b64a8 97 SMART SM00418 13 91 1.2E-24 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TW_RS00340 5d92ca5f5966f78960f58ef2887b64a8 97 SUPERFAMILY SSF46785 6 94 6.3E-24 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS00340 5d92ca5f5966f78960f58ef2887b64a8 97 Pfam PF01022 Bacterial regulatory protein, arsR family 22 65 1.2E-13 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TW_RS00340 5d92ca5f5966f78960f58ef2887b64a8 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 1.5E-13 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TW_RS00340 5d92ca5f5966f78960f58ef2887b64a8 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 1.5E-13 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TW_RS00340 5d92ca5f5966f78960f58ef2887b64a8 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 1.5E-13 T 11-11-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TW_RS02015 70dfe1fd0e34f5e5f0a47e2365692fc5 291 SMART SM00450 19 133 9.8E-12 T 11-11-2016 IPR001763 Rhodanese-like domain TW_RS02015 70dfe1fd0e34f5e5f0a47e2365692fc5 291 SMART SM00450 155 283 1.1E-16 T 11-11-2016 IPR001763 Rhodanese-like domain TW_RS02015 70dfe1fd0e34f5e5f0a47e2365692fc5 291 SUPERFAMILY SSF52821 161 288 4.19E-30 T 11-11-2016 IPR001763 Rhodanese-like domain TW_RS02015 70dfe1fd0e34f5e5f0a47e2365692fc5 291 Pfam PF00581 Rhodanese-like domain 161 278 2.2E-15 T 11-11-2016 IPR001763 Rhodanese-like domain TW_RS02015 70dfe1fd0e34f5e5f0a47e2365692fc5 291 Pfam PF00581 Rhodanese-like domain 23 129 1.7E-12 T 11-11-2016 IPR001763 Rhodanese-like domain TW_RS02015 70dfe1fd0e34f5e5f0a47e2365692fc5 291 Gene3D G3DSA:3.40.250.10 14 148 3.8E-32 T 11-11-2016 IPR001763 Rhodanese-like domain TW_RS02015 70dfe1fd0e34f5e5f0a47e2365692fc5 291 Gene3D G3DSA:3.40.250.10 160 288 7.5E-32 T 11-11-2016 IPR001763 Rhodanese-like domain TW_RS02015 70dfe1fd0e34f5e5f0a47e2365692fc5 291 SUPERFAMILY SSF52821 14 152 3.27E-33 T 11-11-2016 IPR001763 Rhodanese-like domain TW_RS04060 c4001cd9f89b1c8c742d603a27881429 215 Pfam PF06778 Chlorite dismutase 38 203 1.3E-49 T 11-11-2016 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase TW_RS04060 c4001cd9f89b1c8c742d603a27881429 215 SUPERFAMILY SSF54909 4 214 7.24E-58 T 11-11-2016 IPR011008 Dimeric alpha-beta barrel TW_RS04060 c4001cd9f89b1c8c742d603a27881429 215 Gene3D G3DSA:3.30.70.1100 117 214 7.0E-32 T 11-11-2016 TW_RS04060 c4001cd9f89b1c8c742d603a27881429 215 Gene3D G3DSA:3.30.70.1030 37 116 2.5E-4 T 11-11-2016 TW_RS00325 6a97aa2ab84091a401486e112ac51f9d 321 Pfam PF01032 FecCD transport family 20 317 2.4E-74 T 11-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 TW_RS00325 6a97aa2ab84091a401486e112ac51f9d 321 Gene3D G3DSA:1.10.3470.10 9 318 4.9E-72 T 11-11-2016 IPR029022 ABC transporter, BtuC-like TW_RS00325 6a97aa2ab84091a401486e112ac51f9d 321 SUPERFAMILY SSF81345 11 317 3.27E-59 T 11-11-2016 IPR029022 ABC transporter, BtuC-like TW_RS01020 5b9a60d0eb9ac8c1146753b4e1a0dae6 162 Gene3D G3DSA:1.10.10.10 22 63 5.9E-4 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS02000 87a42e2a83de8dd4bc5450e4d6df4940 177 Pfam PF11452 Protein of unknown function (DUF3000) 3 173 5.0E-54 T 11-11-2016 IPR021555 Protein of unknown function DUF3000 TW_RS03700 97fc11aa31b1280b3650ef32b5aba1ec 203 SUPERFAMILY SSF81330 11 105 2.62E-19 T 11-11-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 TW_RS03700 97fc11aa31b1280b3650ef32b5aba1ec 203 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 101 2.4E-23 T 11-11-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 TW_RS00780 7dd19900267b2b524d9c0d074fa16b18 311 SUPERFAMILY SSF161098 91 294 1.07E-13 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TW_RS00780 7dd19900267b2b524d9c0d074fa16b18 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 306 7.1E-36 T 11-11-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 TW_RS04405 cbafebe7c512cb63a0b54e46add99008 300 Gene3D G3DSA:3.40.50.300 43 293 1.3E-60 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04405 cbafebe7c512cb63a0b54e46add99008 300 Pfam PF13614 AAA domain 42 217 5.9E-56 T 11-11-2016 IPR025669 AAA domain TW_RS04405 cbafebe7c512cb63a0b54e46add99008 300 SUPERFAMILY SSF52540 42 291 5.32E-61 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS01395 73ba436442f96f93ae09f3cb8a9e4e16 154 Pfam PF12028 Protein of unknown function (DUF3515) 22 144 1.9E-12 T 11-11-2016 IPR021903 Protein of unknown function DUF3515 TW_RS01690 b80df33ad61b10c33fa3f794caf367b0 173 SUPERFAMILY SSF48452 32 147 5.91E-5 T 11-11-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 TW_RS02150 d1b9562891a4dcf9acb5b2719aa587ff 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 48 427 1.5E-94 T 11-11-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 TW_RS02150 d1b9562891a4dcf9acb5b2719aa587ff 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 5 428 33.013 T 11-11-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686 TW_RS02150 d1b9562891a4dcf9acb5b2719aa587ff 428 Pfam PF01979 Amidohydrolase family 61 425 9.9E-19 T 11-11-2016 IPR006680 Amidohydrolase-related GO:0016787 TW_RS02150 d1b9562891a4dcf9acb5b2719aa587ff 428 SUPERFAMILY SSF51556 65 371 1.4E-85 T 11-11-2016 IPR032466 Metal-dependent hydrolase TW_RS02150 d1b9562891a4dcf9acb5b2719aa587ff 428 SUPERFAMILY SSF51338 371 428 1.48E-13 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 TW_RS02150 d1b9562891a4dcf9acb5b2719aa587ff 428 SUPERFAMILY SSF51338 47 64 1.48E-13 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 TW_RS02150 d1b9562891a4dcf9acb5b2719aa587ff 428 Gene3D G3DSA:2.30.40.10 19 72 1.2E-7 T 11-11-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 TW_RS02150 d1b9562891a4dcf9acb5b2719aa587ff 428 Gene3D G3DSA:3.20.20.140 73 389 2.7E-84 T 11-11-2016 TW_RS00060 079c262be4bd8e2b9332c85358ad2269 69 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 69 21.761 T 11-11-2016 IPR009619 Cell division protein CrgA TW_RS00060 079c262be4bd8e2b9332c85358ad2269 69 Pfam PF06781 Uncharacterised protein family (UPF0233) 3 69 1.8E-20 T 11-11-2016 IPR009619 Cell division protein CrgA TW_RS00315 1f671932f13b7e3ee07f13a025d69316 261 Pfam PF00005 ABC transporter 17 164 2.6E-30 T 11-11-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TW_RS00315 1f671932f13b7e3ee07f13a025d69316 261 Gene3D G3DSA:3.40.50.300 1 233 3.2E-63 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00315 1f671932f13b7e3ee07f13a025d69316 261 SMART SM00382 26 213 3.7E-15 T 11-11-2016 IPR003593 AAA+ ATPase domain TW_RS00315 1f671932f13b7e3ee07f13a025d69316 261 SUPERFAMILY SSF52540 2 226 3.27E-59 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS00315 1f671932f13b7e3ee07f13a025d69316 261 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 11-11-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TW_RS01475 5143d1d16671ad3ef6f6a92b5bc8b7ad 92 Pfam PF13834 Domain of unknown function (DUF4193) 2 91 7.4E-29 T 11-11-2016 IPR025242 Protein of unknown function DUF4193 TW_RS02055 9922463bba1e8950164ded4cb2dc8690 480 PRINTS PR00095 Anthranilate synthase component I signature 426 440 2.8E-14 T 11-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TW_RS02055 9922463bba1e8950164ded4cb2dc8690 480 PRINTS PR00095 Anthranilate synthase component I signature 318 331 2.8E-14 T 11-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TW_RS02055 9922463bba1e8950164ded4cb2dc8690 480 PRINTS PR00095 Anthranilate synthase component I signature 332 345 2.8E-14 T 11-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TW_RS02055 9922463bba1e8950164ded4cb2dc8690 480 PRINTS PR00095 Anthranilate synthase component I signature 410 424 2.8E-14 T 11-11-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TW_RS02055 9922463bba1e8950164ded4cb2dc8690 480 SUPERFAMILY SSF56322 31 477 5.23E-109 T 11-11-2016 IPR005801 ADC synthase GO:0009058 TW_RS02055 9922463bba1e8950164ded4cb2dc8690 480 Pfam PF00425 chorismate binding enzyme 215 469 8.5E-82 T 11-11-2016 IPR015890 Chorismate-utilising enzyme, C-terminal TW_RS02055 9922463bba1e8950164ded4cb2dc8690 480 Gene3D G3DSA:3.60.120.10 32 477 1.0E-113 T 11-11-2016 IPR005801 ADC synthase GO:0009058 TW_RS01150 4b91de53e56be2561c40ccdd1152eeff 103 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 16 103 19.214 T 11-11-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TW_RS01150 4b91de53e56be2561c40ccdd1152eeff 103 Gene3D G3DSA:3.30.70.330 14 102 8.6E-32 T 11-11-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 TW_RS01150 4b91de53e56be2561c40ccdd1152eeff 103 Pfam PF00276 Ribosomal protein L23 17 97 3.6E-30 T 11-11-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TW_RS01150 4b91de53e56be2561c40ccdd1152eeff 103 SUPERFAMILY SSF54189 14 98 4.32E-30 T 11-11-2016 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01150 4b91de53e56be2561c40ccdd1152eeff 103 ProSitePatterns PS00050 Ribosomal protein L23 signature. 88 103 - T 11-11-2016 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS02420 6ec718005a1800741d5b3cc7fa30c8ba 307 PIRSF PIRSF028754 11 297 2.4E-57 T 11-11-2016 IPR008492 Protein of unknown function DUF774 TW_RS02420 6ec718005a1800741d5b3cc7fa30c8ba 307 SUPERFAMILY SSF159659 16 268 5.23E-62 T 11-11-2016 TW_RS02420 6ec718005a1800741d5b3cc7fa30c8ba 307 Pfam PF09754 PAC2 family 26 246 1.8E-34 T 11-11-2016 IPR019151 Proteasome assembly chaperone 2 TW_RS01050 65010513c116b70e91a480c1c77fc1d4 220 Gene3D G3DSA:1.10.1470.10 51 89 8.3E-4 T 11-11-2016 IPR008462 CsbD-like TW_RS00480 0d0baee0462689a14dcee0052a20e2af 359 Gene3D G3DSA:1.20.1250.20 6 171 1.4E-23 T 11-11-2016 TW_RS00480 0d0baee0462689a14dcee0052a20e2af 359 Gene3D G3DSA:1.20.1250.20 181 349 1.7E-14 T 11-11-2016 TW_RS00480 0d0baee0462689a14dcee0052a20e2af 359 Pfam PF07690 Major Facilitator Superfamily 3 292 2.6E-30 T 11-11-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TW_RS00480 0d0baee0462689a14dcee0052a20e2af 359 SUPERFAMILY SSF103473 3 349 5.62E-42 T 11-11-2016 IPR020846 Major facilitator superfamily domain TW_RS00035 ed3c42d4c57dec219425538ba1f493b0 126 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 12 124 3.9E-23 T 11-11-2016 IPR021949 Domain of unknown function DUF3566. transmembrane TW_RS00320 0504c487cc4ccc2f5b381c7b5460a437 344 Gene3D G3DSA:1.10.3470.10 19 340 2.8E-82 T 11-11-2016 IPR029022 ABC transporter, BtuC-like TW_RS00320 0504c487cc4ccc2f5b381c7b5460a437 344 Pfam PF01032 FecCD transport family 31 337 9.5E-82 T 11-11-2016 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 TW_RS00320 0504c487cc4ccc2f5b381c7b5460a437 344 SUPERFAMILY SSF81345 16 337 1.44E-67 T 11-11-2016 IPR029022 ABC transporter, BtuC-like TW_RS02360 aa9839c19b075d3779b5cc092f27a15e 410 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 377 5.2E-36 T 11-11-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 TW_RS01555 2d8a565acf5547629d5aec318c89ecf0 109 Pfam PF14017 Protein of unknown function (DUF4233) 8 102 1.7E-9 T 11-11-2016 IPR025327 Protein of unknown function DUF4233 TW_RS00055 3025f1a840f10cec0224013a013fc36d 207 Gene3D G3DSA:1.20.1540.10 11 181 3.6E-43 T 11-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TW_RS00055 3025f1a840f10cec0224013a013fc36d 207 Pfam PF01694 Rhomboid family 52 182 1.7E-32 T 11-11-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TW_RS00055 3025f1a840f10cec0224013a013fc36d 207 SUPERFAMILY SSF144091 8 183 3.14E-43 T 11-11-2016 TW_RS02080 2c48372856f049fc45155f024004eaf3 309 SUPERFAMILY SSF48019 195 304 7.99E-17 T 11-11-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TW_RS02245 ad3f72cca1fbc05bc0f50b5899dc35ac 160 SUPERFAMILY SSF141259 2 66 6.15E-12 T 11-11-2016 IPR003711 CarD-like/TRCF domain TW_RS02245 ad3f72cca1fbc05bc0f50b5899dc35ac 160 SMART SM01058 2 112 1.7E-27 T 11-11-2016 IPR003711 CarD-like/TRCF domain TW_RS02245 ad3f72cca1fbc05bc0f50b5899dc35ac 160 Pfam PF02559 CarD-like/TRCF domain 3 110 2.6E-11 T 11-11-2016 IPR003711 CarD-like/TRCF domain TW_RS01185 68ff5097127558b6c649b78968a5bebc 86 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 8 79 8.0E-31 T 11-11-2016 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01185 68ff5097127558b6c649b78968a5bebc 86 PRINTS PR00973 Ribosomal protein S17 family signature 59 69 8.3E-12 T 11-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01185 68ff5097127558b6c649b78968a5bebc 86 PRINTS PR00973 Ribosomal protein S17 family signature 27 50 8.3E-12 T 11-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01185 68ff5097127558b6c649b78968a5bebc 86 PRINTS PR00973 Ribosomal protein S17 family signature 69 76 8.3E-12 T 11-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01185 68ff5097127558b6c649b78968a5bebc 86 SUPERFAMILY SSF50249 8 85 2.1E-27 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01185 68ff5097127558b6c649b78968a5bebc 86 Gene3D G3DSA:2.40.50.140 8 85 4.7E-31 T 11-11-2016 IPR012340 Nucleic acid-binding, OB-fold TW_RS01185 68ff5097127558b6c649b78968a5bebc 86 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 6 84 23.361 T 11-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01185 68ff5097127558b6c649b78968a5bebc 86 ProSitePatterns PS00056 Ribosomal protein S17 signature. 59 71 - T 11-11-2016 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TW_RS01185 68ff5097127558b6c649b78968a5bebc 86 Pfam PF00366 Ribosomal protein S17 13 79 4.9E-27 T 11-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS01185 68ff5097127558b6c649b78968a5bebc 86 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 13 79 4.0E-32 T 11-11-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TW_RS02430 46a79772a53973f0032b06b0b4c590cf 279 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 277 16.118 T 11-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TW_RS02430 46a79772a53973f0032b06b0b4c590cf 279 Pfam PF02673 Bacitracin resistance protein BacA 5 271 4.3E-62 T 11-11-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TW_RS03545 5ffc217d5ba718d30b16772939a9abd7 257 Gene3D G3DSA:3.40.50.300 3 251 4.3E-49 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03545 5ffc217d5ba718d30b16772939a9abd7 257 SUPERFAMILY SSF52540 2 249 1.07E-47 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03545 5ffc217d5ba718d30b16772939a9abd7 257 Pfam PF13614 AAA domain 3 175 9.3E-33 T 11-11-2016 IPR025669 AAA domain TW_RS01055 29be3b62be39e9f8e7b65167ab60e83c 205 Gene3D G3DSA:3.40.50.150 8 203 7.2E-37 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS01055 29be3b62be39e9f8e7b65167ab60e83c 205 SUPERFAMILY SSF53335 34 203 9.8E-25 T 11-11-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TW_RS01055 29be3b62be39e9f8e7b65167ab60e83c 205 Pfam PF01596 O-methyltransferase 28 202 2.4E-18 T 11-11-2016 IPR002935 O-methyltransferase, family 3 GO:0008171 TW_RS02570 99c972143b9bb5eee135238c81baedd9 297 Pfam PF00877 NlpC/P60 family 199 293 2.9E-21 T 11-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain TW_RS02570 99c972143b9bb5eee135238c81baedd9 297 SUPERFAMILY SSF54001 179 288 1.47E-34 T 11-11-2016 TW_RS02570 99c972143b9bb5eee135238c81baedd9 297 Gene3D G3DSA:3.90.1720.10 182 290 5.4E-35 T 11-11-2016 IPR000064 Endopeptidase, NLPC/P60 domain TW_RS03145 02b7ab043fc6001ff58af228310a5f15 165 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 28 73 5.6E-5 T 11-11-2016 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal TW_RS03355 e02e601e9f63881202524647e053b050 211 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 19 210 6.0E-23 T 11-11-2016 IPR003744 Protein of unknown function DUF165 TW_RS03355 e02e601e9f63881202524647e053b050 211 Pfam PF02592 Putative vitamin uptake transporter 43 204 2.6E-30 T 11-11-2016 IPR003744 Protein of unknown function DUF165 TW_RS02065 dc74c4405f15f13a98402ac78bcc9d71 193 Pfam PF12836 Helix-hairpin-helix motif 130 191 3.1E-22 T 11-11-2016 TW_RS02065 dc74c4405f15f13a98402ac78bcc9d71 193 Gene3D G3DSA:3.10.560.10 68 112 5.6E-9 T 11-11-2016 TW_RS02065 dc74c4405f15f13a98402ac78bcc9d71 193 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 127 193 1.8E-19 T 11-11-2016 IPR004509 Competence protein ComEA, helix-hairpin-helix domain TW_RS02065 dc74c4405f15f13a98402ac78bcc9d71 193 SUPERFAMILY SSF47781 124 193 1.05E-27 T 11-11-2016 IPR010994 RuvA domain 2-like TW_RS02065 dc74c4405f15f13a98402ac78bcc9d71 193 Pfam PF10531 SLBB domain 70 123 8.1E-11 T 11-11-2016 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TW_RS02065 dc74c4405f15f13a98402ac78bcc9d71 193 Gene3D G3DSA:1.10.150.280 113 193 2.4E-22 T 11-11-2016 TW_RS02065 dc74c4405f15f13a98402ac78bcc9d71 193 SMART SM00278 171 190 1.6 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TW_RS02065 dc74c4405f15f13a98402ac78bcc9d71 193 SMART SM00278 141 160 0.062 T 11-11-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TW_RS02535 f868ee7c14e261a2cdcf8631bf9a6c28 246 Pfam PF01121 Dephospho-CoA kinase 6 109 7.5E-14 T 11-11-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 TW_RS02535 f868ee7c14e261a2cdcf8631bf9a6c28 246 Pfam PF01121 Dephospho-CoA kinase 134 171 8.9E-5 T 11-11-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 TW_RS02535 f868ee7c14e261a2cdcf8631bf9a6c28 246 SUPERFAMILY SSF52540 4 178 6.01E-17 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02535 f868ee7c14e261a2cdcf8631bf9a6c28 246 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 3 205 15.731 T 11-11-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24 TW_RS02535 f868ee7c14e261a2cdcf8631bf9a6c28 246 Gene3D G3DSA:3.40.50.300 3 180 1.9E-34 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS02535 f868ee7c14e261a2cdcf8631bf9a6c28 246 Gene3D G3DSA:3.40.50.300 217 237 1.9E-34 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04360 44d220485edf7ecf717dbdda98f1b90f 105 SUPERFAMILY SSF48600 20 103 1.83E-19 T 11-11-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TW_RS04360 44d220485edf7ecf717dbdda98f1b90f 105 Gene3D G3DSA:1.20.59.10 16 103 1.8E-17 T 11-11-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TW_RS04360 44d220485edf7ecf717dbdda98f1b90f 105 Pfam PF01817 Chorismate mutase type II 25 102 2.1E-14 T 11-11-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TW_RS04360 44d220485edf7ecf717dbdda98f1b90f 105 SMART SM00830 25 105 8.3E-21 T 11-11-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TW_RS04220 f549a636ec0f12c6b6d62710ea4861be 147 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 10 114 1.2E-6 T 11-11-2016 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III TW_RS03685 7aeec6430241a9bd8c796c513d4fb9e8 336 Gene3D G3DSA:3.40.630.30 205 326 1.5E-21 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase TW_RS03685 7aeec6430241a9bd8c796c513d4fb9e8 336 Pfam PF00583 Acetyltransferase (GNAT) family 250 321 1.3E-9 T 11-11-2016 IPR000182 GNAT domain GO:0008080 TW_RS03685 7aeec6430241a9bd8c796c513d4fb9e8 336 SUPERFAMILY SSF55729 203 327 8.68E-27 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase TW_RS03685 7aeec6430241a9bd8c796c513d4fb9e8 336 SUPERFAMILY SSF55729 86 157 8.68E-27 T 11-11-2016 IPR016181 Acyl-CoA N-acyltransferase TW_RS03660 4b7b30c4c8e8e89af295974008ce92f2 192 Gene3D G3DSA:1.10.10.10 41 81 2.3E-4 T 11-11-2016 IPR011991 Winged helix-turn-helix DNA-binding domain TW_RS03595 997cfad13918227f9e9a72f19c3668c6 433 Pfam PF02646 RmuC family 91 379 1.2E-69 T 11-11-2016 IPR003798 DNA recombination RmuC TW_RS01330 9d195df6dbc320d9669f3410fdb07024 424 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 37 379 3.6E-70 T 11-11-2016 IPR018766 Zinicin-like metallopeptidase type 2 TW_RS01330 9d195df6dbc320d9669f3410fdb07024 424 Pfam PF10103 Zinicin-like metallopeptidase 37 375 2.6E-78 T 11-11-2016 IPR018766 Zinicin-like metallopeptidase type 2 TW_RS01330 9d195df6dbc320d9669f3410fdb07024 424 SUPERFAMILY SSF55486 36 379 1.17E-75 T 11-11-2016 TW_RS01975 6aec6fe7424fb333b286287ee6e55fcf 203 Gene3D G3DSA:3.40.30.10 9 161 1.7E-5 T 11-11-2016 IPR012336 Thioredoxin-like fold TW_RS01975 6aec6fe7424fb333b286287ee6e55fcf 203 SUPERFAMILY SSF52833 10 166 1.57E-12 T 11-11-2016 IPR012336 Thioredoxin-like fold TW_RS02115 c6892a29da8f76a258807cf789dba182 395 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 62 388 1.9E-55 T 11-11-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like TW_RS02115 c6892a29da8f76a258807cf789dba182 395 Pfam PF02618 YceG-like family 99 381 6.9E-67 T 11-11-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like TW_RS02115 c6892a29da8f76a258807cf789dba182 395 Gene3D G3DSA:3.30.160.60 355 389 1.8E-6 T 11-11-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 TW_RS00700 ee874b02711fa672bd4118b1118788f4 90 Pfam PF02467 Transcription factor WhiB 17 79 9.0E-27 T 11-11-2016 IPR003482 Transcription factor WhiB TW_RS00700 ee874b02711fa672bd4118b1118788f4 90 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 11 85 18.973 T 11-11-2016 IPR003482 Transcription factor WhiB TW_RS03735 8b6481cfced8f7d50408b4e241e6396d 1172 Gene3D G3DSA:3.40.50.300 240 353 1.2E-8 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03735 8b6481cfced8f7d50408b4e241e6396d 1172 Gene3D G3DSA:3.40.50.300 787 892 1.2E-8 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03735 8b6481cfced8f7d50408b4e241e6396d 1172 SUPERFAMILY SSF52540 245 317 2.66E-10 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03735 8b6481cfced8f7d50408b4e241e6396d 1172 SUPERFAMILY SSF52540 763 1047 2.66E-10 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS04320 c1e35aa1de39a8cf8a5065dfa6edec0f 385 Gene3D G3DSA:1.20.1530.10 3 370 7.9E-96 T 11-11-2016 IPR023171 Na/H antiporter domain TW_RS04320 c1e35aa1de39a8cf8a5065dfa6edec0f 385 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 1 372 17.442 T 11-11-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TW_RS04320 c1e35aa1de39a8cf8a5065dfa6edec0f 385 Pfam PF06965 Na+/H+ antiporter 1 3 364 2.6E-94 T 11-11-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 TW_RS02320 1bed1971097247efaaaa7401247de1a3 384 SUPERFAMILY SSF101960 22 375 1.26E-72 T 11-11-2016 TW_RS02320 1bed1971097247efaaaa7401247de1a3 384 Pfam PF01458 Uncharacterized protein family (UPF0051) 130 350 3.6E-61 T 11-11-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TW_RS02310 c5e7d8c3df9a6f880e6f871f3237c5f3 351 Pfam PF02628 Cytochrome oxidase assembly protein 98 220 2.2E-8 T 11-11-2016 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 TW_RS00435 52b5b0bacbd573df3991255e7355e1ef 246 Pfam PF02104 SURF1 family 28 223 5.3E-6 T 11-11-2016 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TW_RS00860 252a173aec1e5b0d66104acccf5931c7 192 Pfam PF05345 Putative Ig domain 9 47 2.8E-8 T 11-11-2016 IPR008009 Putative Ig TW_RS02485 47a012a3c6e5c1f50d3ef2f6989a54e5 121 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 22 121 16.724 T 11-11-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 TW_RS02485 47a012a3c6e5c1f50d3ef2f6989a54e5 121 Pfam PF13397 RNA polymerase-binding protein 20 116 7.5E-24 T 11-11-2016 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 TW_RS01490 771c949cf29df1b32252597f555ba91b 200 Pfam PF12502 Protein of unknown function (DUF3710) 17 192 2.8E-53 T 11-11-2016 IPR022183 Protein of unknown function DUF3710 TW_RS04025 d51b1345227bb5518f648ad25d81f3ca 387 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 86 241 5.5E-33 T 11-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain TW_RS04025 d51b1345227bb5518f648ad25d81f3ca 387 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 86 241 2.8E-35 T 11-11-2016 IPR004474 Cell envelope-related transcriptional attenuator domain TW_RS04045 f5e9bec76b5b1c8df72e2073447b4ebe 241 Gene3D G3DSA:3.40.50.10090 35 154 5.9E-14 T 11-11-2016 TW_RS04045 f5e9bec76b5b1c8df72e2073447b4ebe 241 SUPERFAMILY SSF69618 7 239 9.42E-34 T 11-11-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS04045 f5e9bec76b5b1c8df72e2073447b4ebe 241 Gene3D G3DSA:3.40.50.10090 155 237 2.3E-8 T 11-11-2016 TW_RS04045 f5e9bec76b5b1c8df72e2073447b4ebe 241 Pfam PF02602 Uroporphyrinogen-III synthase HemD 19 235 7.9E-29 T 11-11-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TW_RS00140 a117d846f7f3cf9b2f75d5daff467483 153 Pfam PF04138 GtrA-like protein 25 149 8.1E-23 T 11-11-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 TW_RS00200 7aa7ca45fc569d3bb100de20d699ba48 118 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 5 100 2.0E-24 T 11-11-2016 IPR019277 Protein of unknown function DUF2304 TW_RS01495 23af7a18d3fb30297243ac7398344a00 218 Pfam PF11361 Protein of unknown function (DUF3159) 31 215 4.6E-58 T 11-11-2016 IPR016566 Uncharacterised conserved protein UCP010219 TW_RS01495 23af7a18d3fb30297243ac7398344a00 218 PIRSF PIRSF010219 4 218 1.2E-79 T 11-11-2016 IPR016566 Uncharacterised conserved protein UCP010219 TW_RS02865 f1fbc433c07740a919969a1020d1a4b8 249 Pfam PF08478 POTRA domain, FtsQ-type 57 124 5.1E-14 T 11-11-2016 IPR013685 Polypeptide-transport-associated, FtsQ-type TW_RS03715 1b953f0924206c7bf6cc0de978657934 284 Gene3D G3DSA:1.10.3470.10 55 261 2.0E-8 T 11-11-2016 IPR029022 ABC transporter, BtuC-like TW_RS03715 1b953f0924206c7bf6cc0de978657934 284 Pfam PF00950 ABC 3 transport family 11 263 8.6E-73 T 11-11-2016 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TW_RS03715 1b953f0924206c7bf6cc0de978657934 284 SUPERFAMILY SSF81345 3 261 1.83E-37 T 11-11-2016 IPR029022 ABC transporter, BtuC-like TW_RS03855 6722526e77b6f114705ae6f14af9b1eb 411 Gene3D G3DSA:3.40.50.300 41 201 7.6E-32 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03855 6722526e77b6f114705ae6f14af9b1eb 411 SUPERFAMILY SSF52540 40 242 4.35E-30 T 11-11-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase TW_RS03855 6722526e77b6f114705ae6f14af9b1eb 411 Pfam PF13177 DNA polymerase III, delta subunit 50 202 4.3E-26 T 11-11-2016 TW_RS02370 cfa8834ddb1aeb38f60d098130478f3b 313 SUPERFAMILY SSF56601 6 272 1.04E-29 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like TW_RS02370 cfa8834ddb1aeb38f60d098130478f3b 313 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 78 270 4.5E-13 T 11-11-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 TW_RS02370 cfa8834ddb1aeb38f60d098130478f3b 313 Gene3D G3DSA:3.40.710.10 76 285 8.7E-33 T 11-11-2016 IPR012338 Beta-lactamase/transpeptidase-like TW_RS03525 6ba62c31e5516b16631df3c62b928a87 958 Pfam PF03699 Uncharacterised protein family (UPF0182) 18 824 2.6E-260 T 11-11-2016 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 TW_RS03525 6ba62c31e5516b16631df3c62b928a87 958 Hamap MF_01600 UPF0182 protein . 6 902 18.37 T 11-11-2016 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 TW_RS03880 cfea03e0f686ee8c45ddaf76090a34bd 68 Pfam PF14029 Protein of unknown function (DUF4244) 15 65 2.7E-20 T 11-11-2016 IPR025338 Protein of unknown function DUF4244 TW_RS02790 8f62db7b9c041794dac05fe0c7923b83 139 Pfam PF12270 Cytochrome c oxidase subunit IV 3 136 2.7E-32 T 11-11-2016 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TW_RS01370 416d718e1ac636eddd1b8bbbfafbbea8 317 Pfam PF03741 Integral membrane protein TerC family 64 263 4.6E-50 T 11-11-2016 IPR005496 Integral membrane protein TerC GO:0016021 TW_RS01370 416d718e1ac636eddd1b8bbbfafbbea8 317 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 6 309 5.9E-85 T 11-11-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 TW_RS03225 dd6d75e5dd853489a7f27f941a31c90c 488 Pfam PF01554 MatE 15 172 8.9E-12 T 11-11-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TW_RS02765 94aa7ef93d67e5cc113c29ae3061f2d2 164 Pfam PF11343 Protein of unknown function (DUF3145) 13 159 2.1E-52 T 11-11-2016 IPR021491 Protein of unknown function DUF3145 TW_RS02040 1137430cfd75c0324dfbcdcaaf493de7 402 SUPERFAMILY SSF53955 328 395 3.26E-6 T 11-11-2016 IPR023346 Lysozyme-like domain TW_RS02390 dd1113a416355b28425d233692493870 89 Pfam PF11238 Protein of unknown function (DUF3039) 32 87 2.1E-24 T 11-11-2016 IPR021400 Protein of unknown function DUF3039 TW_RS00725 f55d13404bbc0d6ca8f31792848c5f20 254 Gene3D G3DSA:3.40.50.2020 70 230 1.0E-11 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like TW_RS00725 f55d13404bbc0d6ca8f31792848c5f20 254 SUPERFAMILY SSF53271 70 221 4.66E-10 T 11-11-2016 IPR029057 Phosphoribosyltransferase-like TW_RS00675 b2eca971259ace09b05b2d525aa7e74f 701 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 426 668 5.5E-64 T 11-11-2016 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related TW_RS01735 b8f3d7de93b711fb41ef35e65c334696 212 Pfam PF01464 Transglycosylase SLT domain 137 198 1.3E-5 T 11-11-2016 IPR008258 Transglycosylase SLT domain 1 TW_RS01735 b8f3d7de93b711fb41ef35e65c334696 212 Gene3D G3DSA:1.10.530.10 140 204 1.5E-5 T 11-11-2016 TW_RS01735 b8f3d7de93b711fb41ef35e65c334696 212 SUPERFAMILY SSF53955 137 205 4.22E-11 T 11-11-2016 IPR023346 Lysozyme-like domain TW_RS01305 14bab254cd1421e3e83766060285da48 73 Pfam PF11305 Protein of unknown function (DUF3107) 1 71 5.4E-17 T 11-11-2016 IPR021456 Protein of unknown function DUF3107 TW_RS02045 27496dc02e6e47fd6846f34370c47f78 371 Pfam PF13515 Fusaric acid resistance protein-like 38 160 4.8E-9 T 11-11-2016 TW_RS00190 b8edf53dd416c0f2ed53c538afc0a702 293 Pfam PF01061 ABC-2 type transporter 36 247 1.2E-18 T 11-11-2016 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TW_RS00705 d4f476c13c4a899d0c836ef7d866fbc1 853 Gene3D G3DSA:3.90.550.10 12 213 1.5E-17 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS00705 d4f476c13c4a899d0c836ef7d866fbc1 853 SUPERFAMILY SSF53448 12 258 1.22E-23 T 11-11-2016 IPR029044 Nucleotide-diphospho-sugar transferases TW_RS04455 5a569cf0bc1a70618aa5898241801a97 387 Pfam PF05345 Putative Ig domain 50 88 7.5E-12 T 11-11-2016 IPR008009 Putative Ig