locus-tag	class	description
DBV13_RS00025	COG0647	UMP catabolic process
DBV13_RS00035	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DBV13_RS00040	COG0497	DNA recombination
DBV13_RS00060	COG0728	peptidoglycan biosynthetic process
DBV13_RS00090	COG0396	ATPase activity
DBV13_RS00105	COG2151	metal-sulfur cluster biosynthetic enzyme
DBV13_RS00110	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DBV13_RS00115	COG0488	(ABC) transporter
DBV13_RS00125	COG0560	Phosphoserine phosphatase
DBV13_RS00125	COG3830	Belongs to the UPF0237 family
DBV13_RS00140	COG1136	(ABC) transporter
DBV13_RS00150	COG0297	glycogen (starch) synthase activity
DBV13_RS00155	COG1119	ATPase activity
DBV13_RS00190	COG1881	PFAM PEBP family protein
DBV13_RS00205	COG0587	DNA-directed DNA polymerase activity
DBV13_RS00225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DBV13_RS00230	COG0519	Catalyzes the synthesis of GMP from XMP
DBV13_RS00230	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DBV13_RS00240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DBV13_RS00255	COG1968	undecaprenyl-diphosphatase activity
DBV13_RS00275	COG1222	aaa ATPase
DBV13_RS00280	COG4122	O-methyltransferase activity
DBV13_RS00290	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DBV13_RS00305	COG0107	imidazoleglycerol-phosphate synthase activity
DBV13_RS00315	COG0134	indole-3-glycerol-phosphate synthase activity
DBV13_RS00320	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DBV13_RS00325	COG0469	pyruvate kinase activity
DBV13_RS00350	COG0539	negative regulation of cytoplasmic translation
DBV13_RS00360	COG1136	(ABC) transporter
DBV13_RS00365	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DBV13_RS00370	COG0237	dephospho-CoA kinase activity
DBV13_RS00375	COG0556	nucleotide-excision repair
DBV13_RS00395	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DBV13_RS00400	COG0322	excinuclease ABC activity
DBV13_RS00415	COG1481	regulation of sporulation
DBV13_RS00420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DBV13_RS00425	COG0126	phosphoglycerate kinase activity
DBV13_RS00430	COG0149	triose-phosphate isomerase activity
DBV13_RS00435	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DBV13_RS00450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DBV13_RS00475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DBV13_RS00490	COG1160	GTP binding
DBV13_RS00495	COG0205	6-phosphofructokinase activity
DBV13_RS00535	COG1216	Glycosyl transferase, family 2
DBV13_RS00545	COG4581	dead DEAH box helicase
DBV13_RS00575	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DBV13_RS00580	COG0140	phosphoribosyl-ATP diphosphatase activity
DBV13_RS00585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DBV13_RS00590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DBV13_RS00595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DBV13_RS00605	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DBV13_RS00610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DBV13_RS00615	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DBV13_RS00625	COG1758	RNA polymerase activity
DBV13_RS00630	COG0194	GDP metabolic process
DBV13_RS00640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DBV13_RS00645	COG0505	Belongs to the CarA family
DBV13_RS00650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DBV13_RS00655	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DBV13_RS00660	COG2217	Heavy metal translocating P-type atpase
DBV13_RS00665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DBV13_RS00675	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DBV13_RS00695	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DBV13_RS00700	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DBV13_RS00710	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DBV13_RS00720	COG2409	Drug exporters of the RND superfamily
DBV13_RS00735	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DBV13_RS00755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DBV13_RS00760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DBV13_RS00765	COG0124	histidyl-tRNA synthetase
DBV13_RS00770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBV13_RS00775	COG1196	nuclear chromosome segregation
DBV13_RS00785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DBV13_RS00790	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DBV13_RS00795	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DBV13_RS00800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DBV13_RS00810	COG2255	four-way junction helicase activity
DBV13_RS00815	COG0632	four-way junction helicase activity
DBV13_RS00820	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DBV13_RS00825	COG0217	transcriptional regulatory protein
DBV13_RS00830	COG1051	belongs to the nudix hydrolase family
DBV13_RS00840	COG0438	transferase activity, transferring glycosyl groups
DBV13_RS00850	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DBV13_RS00855	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DBV13_RS00860	COG1760	l-serine dehydratase
DBV13_RS00865	COG2197	response regulator
DBV13_RS00930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DBV13_RS00940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DBV13_RS00955	COG0569	domain protein
DBV13_RS01000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DBV13_RS01015	COG0187	DNA topoisomerase II activity
DBV13_RS01025	COG1199	ATP-dependent helicase activity
DBV13_RS01025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DBV13_RS01030	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DBV13_RS01045	COG0142	geranyltranstransferase activity
DBV13_RS01055	COG3858	chitin binding
DBV13_RS01055	COG1388	LysM domain
DBV13_RS01065	COG0515	serine threonine protein kinase
DBV13_RS01065	COG2815	serine threonine protein kinase
DBV13_RS01070	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DBV13_RS01075	COG0205	6-phosphofructokinase activity
DBV13_RS01115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DBV13_RS01130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DBV13_RS01140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBV13_RS01145	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBV13_RS01165	COG0174	glutamine synthetase
DBV13_RS01175	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DBV13_RS01180	COG0174	glutamine synthetase
DBV13_RS01195	COG1940	carbohydrate kinase activity
DBV13_RS01215	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DBV13_RS01220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DBV13_RS01225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DBV13_RS01250	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DBV13_RS01270	COG0009	L-threonylcarbamoyladenylate synthase
DBV13_RS01290	COG1090	epimerase
DBV13_RS01305	COG4974	Belongs to the 'phage' integrase family
DBV13_RS01450	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DBV13_RS01455	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBV13_RS01490	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DBV13_RS01495	COG0805	protein transport
DBV13_RS01505	COG0358	DNA primase activity
DBV13_RS01530	COG0423	glycine-tRNA ligase activity
DBV13_RS01545	COG1121	(ABC) transporter
DBV13_RS01550	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBV13_RS01555	COG0735	belongs to the Fur family
DBV13_RS01570	COG0587	DNA-directed DNA polymerase activity
DBV13_RS01585	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DBV13_RS01600	COG1799	cell septum assembly
DBV13_RS01610	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DBV13_RS01620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DBV13_RS01625	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DBV13_RS01630	COG0772	Belongs to the SEDS family
DBV13_RS01635	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DBV13_RS01640	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DBV13_RS01645	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DBV13_RS01650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DBV13_RS01655	COG0768	penicillin binding
DBV13_RS01665	COG0275	rRNA processing
DBV13_RS01670	COG2001	Belongs to the MraZ family
DBV13_RS01680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DBV13_RS01700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DBV13_RS01705	COG0318	PFAM AMP-dependent synthetase and ligase
DBV13_RS01710	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DBV13_RS01720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DBV13_RS01730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DBV13_RS01740	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DBV13_RS01745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DBV13_RS01750	COG2137	regulation of response to DNA damage stimulus
DBV13_RS01755	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DBV13_RS01765	COG1396	sequence-specific DNA binding
DBV13_RS01770	COG1546	Belongs to the CinA family
DBV13_RS01770	COG1058	Belongs to the CinA family
DBV13_RS01785	COG1674	ftsk spoiiie
DBV13_RS01790	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DBV13_RS01805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DBV13_RS01810	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DBV13_RS01815	COG0612	Peptidase, M16
DBV13_RS01825	COG1185	polyribonucleotide nucleotidyltransferase activity
DBV13_RS01870	COG3842	ATPase activity
DBV13_RS01880	COG2271	Major facilitator Superfamily
DBV13_RS01885	COG0745	RESPONSE REGULATOR receiver
DBV13_RS01890	COG3852	Histidine kinase
DBV13_RS01895	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DBV13_RS01900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DBV13_RS01905	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DBV13_RS01920	COG0779	Required for maturation of 30S ribosomal subunits
DBV13_RS01930	COG0442	prolyl-tRNA aminoacylation
DBV13_RS01940	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DBV13_RS01945	COG0750	zinc metalloprotease
DBV13_RS01950	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DBV13_RS01960	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DBV13_RS01970	COG0233	cytoplasmic translational termination
DBV13_RS01995	COG0644	oxidoreductase
DBV13_RS02000	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DBV13_RS02010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DBV13_RS02015	COG0052	Belongs to the universal ribosomal protein uS2 family
DBV13_RS02020	COG2860	membrane
DBV13_RS02025	COG4942	peptidase
DBV13_RS02025	COG1388	LysM domain
DBV13_RS02030	COG4974	Belongs to the 'phage' integrase family
DBV13_RS02055	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DBV13_RS02060	COG0681	Belongs to the peptidase S26 family
DBV13_RS02065	COG2239	Acts as a magnesium transporter
DBV13_RS02075	COG0335	large ribosomal subunit rRNA binding
DBV13_RS02085	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DBV13_RS02090	COG1837	Belongs to the UPF0109 family
DBV13_RS02095	COG0228	four-way junction DNA binding
DBV13_RS02100	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DBV13_RS02140	COG0105	UTP biosynthetic process
DBV13_RS02145	COG0285	dihydrofolate synthase activity
DBV13_RS02150	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DBV13_RS02165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DBV13_RS02185	COG0287	Prephenate dehydrogenase
DBV13_RS02185	COG1605	Chorismate mutase
DBV13_RS02190	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DBV13_RS02195	COG0740	serine-type endopeptidase activity
DBV13_RS02200	COG0740	serine-type endopeptidase activity
DBV13_RS02205	COG0544	peptidyl-prolyl cis-trans isomerase activity
DBV13_RS02210	COG0667	Aldo Keto reductase
DBV13_RS02230	COG3250	beta-galactosidase activity
DBV13_RS02235	COG1609	Transcriptional regulator
DBV13_RS02250	COG0488	(ABC) transporter
DBV13_RS02265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DBV13_RS02280	COG1739	Uncharacterized protein family UPF0029
DBV13_RS02290	COG1045	serine acetyltransferase
DBV13_RS02300	COG3590	peptidase
DBV13_RS02305	COG2354	Protein conserved in bacteria
DBV13_RS02315	COG0519	Catalyzes the synthesis of GMP from XMP
DBV13_RS02330	COG1946	Acyl-CoA thioesterase
DBV13_RS02360	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DBV13_RS02390	COG0463	Glycosyl transferase, family 2
DBV13_RS02395	COG2244	polysaccharide biosynthetic process
DBV13_RS02405	COG0463	Glycosyl transferase, family 2
DBV13_RS02420	COG1216	Glycosyl transferase, family 2
DBV13_RS02420	COG1442	glycosyl transferase family 8
DBV13_RS02425	COG3475	LICD family
DBV13_RS02430	COG4750	Nucleotidyl transferase
DBV13_RS02435	COG0438	transferase activity, transferring glycosyl groups
DBV13_RS02465	COG1882	Formate acetyltransferase
DBV13_RS02470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DBV13_RS02495	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DBV13_RS02500	COG0440	acetolactate synthase activity
DBV13_RS02510	COG2985	domain, Protein
DBV13_RS02510	COG0569	domain protein
DBV13_RS02515	COG0129	dihydroxy-acid dehydratase activity
DBV13_RS02540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBV13_RS02545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBV13_RS02550	COG1121	(ABC) transporter
DBV13_RS02555	COG0803	Belongs to the bacterial solute-binding protein 9 family
DBV13_RS02560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DBV13_RS02565	COG1131	(ABC) transporter
DBV13_RS02575	COG1476	TRANSCRIPTIONal
DBV13_RS02585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DBV13_RS02590	COG1438	arginine binding
DBV13_RS02605	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DBV13_RS02610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DBV13_RS02625	COG1902	pentaerythritol trinitrate reductase activity
DBV13_RS02630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBV13_RS02645	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DBV13_RS02650	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DBV13_RS02660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DBV13_RS02665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DBV13_RS02675	COG0131	Imidazoleglycerol-phosphate dehydratase
DBV13_RS02685	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DBV13_RS02690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DBV13_RS02695	COG1381	Involved in DNA repair and RecF pathway recombination
DBV13_RS02700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DBV13_RS02735	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DBV13_RS02745	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DBV13_RS02750	COG0484	heat shock protein binding
DBV13_RS02755	COG1420	regulation of RNA biosynthetic process
DBV13_RS02775	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DBV13_RS02780	COG0481	GTPase activity
DBV13_RS02805	COG0268	Binds directly to 16S ribosomal RNA
DBV13_RS02810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DBV13_RS02815	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DBV13_RS02835	COG0433	COG0433 Predicted ATPase
DBV13_RS02850	COG0495	leucyl-tRNA aminoacylation
DBV13_RS02875	COG0813	purine-nucleoside phosphorylase activity
DBV13_RS02885	COG1435	thymidine kinase activity
DBV13_RS02905	COG0803	Belongs to the bacterial solute-binding protein 9 family
DBV13_RS02915	COG1121	(ABC) transporter
DBV13_RS02920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DBV13_RS02935	COG0671	phosphoesterase, PA-phosphatase related
DBV13_RS02955	COG1113	amino acid transport
DBV13_RS02960	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DBV13_RS02960	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DBV13_RS02970	COG2011	ABC-type metal ion transport system permease component
DBV13_RS02975	COG1464	Belongs to the NlpA lipoprotein family
DBV13_RS02980	COG1113	amino acid transport
DBV13_RS02990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DBV13_RS02995	COG2186	Transcriptional regulator
DBV13_RS03000	COG0477	Major facilitator Superfamily
DBV13_RS03010	COG0826	peptidase U32
DBV13_RS03020	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DBV13_RS03030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBV13_RS03070	COG0726	polysaccharide deacetylase
DBV13_RS03075	COG0133	tryptophan synthase activity
DBV13_RS03080	COG1609	Transcriptional regulator
DBV13_RS03090	COG0738	Major facilitator superfamily
DBV13_RS03095	COG0235	Class ii aldolase
DBV13_RS03150	COG4824	toxin secretion phage lysis holin
DBV13_RS03235	COG0740	serine-type endopeptidase activity
DBV13_RS03240	COG4695	Portal protein
DBV13_RS03280	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DBV13_RS03330	COG3617	BRO family, N-terminal domain
DBV13_RS03350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DBV13_RS03350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DBV13_RS03410	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DBV13_RS03435	COG0406	alpha-ribazole phosphatase activity
DBV13_RS03440	COG0799	negative regulation of ribosome biogenesis
DBV13_RS03450	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DBV13_RS03455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DBV13_RS03465	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DBV13_RS03475	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DBV13_RS03480	COG1530	ribonuclease E activity
DBV13_RS03485	COG1271	oxidase subunit
DBV13_RS03490	COG1294	oxidase, subunit
DBV13_RS03495	COG4988	ABC transporter
DBV13_RS03500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DBV13_RS03510	COG1132	(ABC) transporter
DBV13_RS03515	COG1132	(ABC) transporter
DBV13_RS03535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DBV13_RS03540	COG0571	ribonuclease III activity
DBV13_RS03555	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DBV13_RS03570	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DBV13_RS03580	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DBV13_RS03590	COG1181	Belongs to the D-alanine--D-alanine ligase family
DBV13_RS03595	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DBV13_RS03615	COG0438	transferase activity, transferring glycosyl groups
DBV13_RS03630	COG4975	Glucose uptake
DBV13_RS03635	COG0339	signal peptide processing
DBV13_RS03690	COG0179	Fumarylacetoacetate (FAA) hydrolase
DBV13_RS03695	COG1022	Amp-dependent synthetase and ligase
DBV13_RS03720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DBV13_RS03725	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DBV13_RS03735	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DBV13_RS03745	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DBV13_RS03770	COG0569	domain protein
DBV13_RS03770	COG2985	domain, Protein
DBV13_RS03785	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DBV13_RS03810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DBV13_RS03830	COG1846	Transcriptional regulator
DBV13_RS03860	COG1619	proteins homologs of microcin C7 resistance protein MccF
DBV13_RS03875	COG0739	heme binding
DBV13_RS03880	COG2177	Part of the ABC transporter FtsEX involved in
DBV13_RS03885	COG2884	Cell division ATP-binding protein ftsE
DBV13_RS03890	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DBV13_RS03950	COG0513	Belongs to the DEAD box helicase family
DBV13_RS03955	COG2095	MarC family integral membrane protein
DBV13_RS03965	COG0006	proline dipeptidase activity
DBV13_RS03970	COG2239	Acts as a magnesium transporter
DBV13_RS03995	COG1611	Belongs to the LOG family
DBV13_RS04005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DBV13_RS04010	COG1309	transcriptional regulator
DBV13_RS04015	COG2814	Major facilitator Superfamily
DBV13_RS04020	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DBV13_RS04040	COG1079	Belongs to the binding-protein-dependent transport system permease family
DBV13_RS04045	COG4603	Belongs to the binding-protein-dependent transport system permease family
DBV13_RS04050	COG3845	ABC transporter
DBV13_RS04055	COG1744	ABC transporter substrate-binding protein PnrA-like
DBV13_RS04075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DBV13_RS04080	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DBV13_RS04090	COG1268	BioY protein
DBV13_RS04095	COG0736	holo-[acyl-carrier-protein] synthase activity
DBV13_RS04100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DBV13_RS04105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DBV13_RS04110	COG4770	biotin carboxylase activity
DBV13_RS04135	COG0644	oxidoreductase
DBV13_RS04140	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DBV13_RS04155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DBV13_RS04160	COG2271	Major facilitator Superfamily
DBV13_RS04165	COG2030	dehydratase
DBV13_RS04195	COG0110	maltose O-acetyltransferase activity
DBV13_RS04205	COG0039	L-malate dehydrogenase activity
DBV13_RS04220	COG0166	Belongs to the GPI family
DBV13_RS04225	COG0205	6-phosphofructokinase activity
DBV13_RS04255	COG0045	succinate-CoA ligase (ADP-forming) activity
DBV13_RS04260	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DBV13_RS04260	COG2755	lipolytic protein G-D-S-L family
DBV13_RS04315	COG4974	Belongs to the 'phage' integrase family
DBV13_RS04340	COG0280	phosphate acetyltransferase
DBV13_RS04340	COG0857	belongs to the CobB CobQ family
DBV13_RS04345	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DBV13_RS04360	COG1136	(ABC) transporter
DBV13_RS04370	COG0114	fumarate hydratase activity
DBV13_RS04375	COG0516	GMP reductase activity
DBV13_RS04400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DBV13_RS04405	COG0151	Belongs to the GarS family
DBV13_RS04410	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DBV13_RS04415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DBV13_RS04420	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DBV13_RS04425	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DBV13_RS04430	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DBV13_RS04440	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DBV13_RS04450	COG0428	transporter
DBV13_RS04455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DBV13_RS04460	COG0733	neurotransmitter:sodium symporter activity
DBV13_RS04470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DBV13_RS04475	COG1053	succinate dehydrogenase
DBV13_RS04500	COG0802	atpase or kinase
DBV13_RS04505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DBV13_RS04515	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DBV13_RS04520	COG1072	(Pantothenic acid kinase))
DBV13_RS04530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DBV13_RS04535	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DBV13_RS04545	COG4720	Psort location CytoplasmicMembrane, score
DBV13_RS04550	COG1122	ATPase activity
DBV13_RS04570	COG0101	tRNA pseudouridine synthase activity
DBV13_RS04575	COG1940	carbohydrate kinase activity
DBV13_RS04585	COG0765	amino acid transport
DBV13_RS04590	COG4598	ABC transporter
DBV13_RS04595	COG0789	Transcriptional regulator
DBV13_RS04605	COG0203	ribosomal protein L17
DBV13_RS04610	COG0202	RNA polymerase activity
DBV13_RS04620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DBV13_RS04625	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DBV13_RS04630	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DBV13_RS04640	COG0563	adenylate kinase activity
DBV13_RS04650	COG0200	Binds to the 23S rRNA
DBV13_RS04655	COG1841	ribosomal large subunit assembly
DBV13_RS04660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DBV13_RS04670	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DBV13_RS04675	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DBV13_RS04680	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DBV13_RS04685	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DBV13_RS04690	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DBV13_RS04695	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DBV13_RS04710	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DBV13_RS04715	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DBV13_RS04720	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DBV13_RS04725	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DBV13_RS04730	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DBV13_RS04735	COG0089	rRNA binding
DBV13_RS04740	COG0088	Forms part of the polypeptide exit tunnel
DBV13_RS04745	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DBV13_RS04750	COG0051	transcription antitermination factor activity, RNA binding
DBV13_RS04755	COG0546	phosphoglycolate phosphatase activity
DBV13_RS04765	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DBV13_RS04770	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DBV13_RS04775	COG0049	tRNA binding
DBV13_RS04780	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DBV13_RS04785	COG0833	amino acid
DBV13_RS04790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DBV13_RS04795	COG0085	RNA polymerase activity
DBV13_RS04800	COG0222	ribosome binding
DBV13_RS04805	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DBV13_RS04815	COG0081	regulation of translation
DBV13_RS04820	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DBV13_RS04825	COG0250	Participates in transcription elongation, termination and antitermination
DBV13_RS04840	COG0436	Aminotransferase
DBV13_RS04850	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DBV13_RS04865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DBV13_RS04875	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DBV13_RS04895	COG1666	GTP binding
DBV13_RS04905	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DBV13_RS04915	COG5401	PFAM Sporulation and spore germination
DBV13_RS04920	COG5002	protein histidine kinase activity
DBV13_RS04925	COG0745	RESPONSE REGULATOR receiver
DBV13_RS04945	COG0714	Associated with various cellular activities
DBV13_RS04990	COG0483	inositol monophosphate 1-phosphatase activity
DBV13_RS05005	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DBV13_RS05100	COG0673	inositol 2-dehydrogenase activity
DBV13_RS05125	COG1088	dTDP-glucose 4,6-dehydratase activity
DBV13_RS05140	COG1316	TRANSCRIPTIONal
DBV13_RS05145	COG1316	TRANSCRIPTIONal
DBV13_RS05155	COG0642	Histidine kinase
DBV13_RS05160	COG0745	RESPONSE REGULATOR receiver
DBV13_RS05175	COG0424	maF-like protein
DBV13_RS05210	COG1217	gtp-binding protein TYPA
DBV13_RS05220	COG1132	(ABC) transporter
DBV13_RS05250	COG0321	lipoyl(octanoyl) transferase activity
DBV13_RS05255	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DBV13_RS05265	COG1362	aminopeptidase activity
DBV13_RS05280	COG2838	Isocitrate dehydrogenase
DBV13_RS05285	COG2391	methyltransferase activity
DBV13_RS05290	COG0425	Belongs to the sulfur carrier protein TusA family
DBV13_RS05295	COG0366	Alpha amylase catalytic
DBV13_RS05300	COG1501	Belongs to the glycosyl hydrolase 31 family
DBV13_RS05310	COG0395	ABC-type sugar transport system, permease component
DBV13_RS05315	COG1175	transmembrane transport
DBV13_RS05320	COG1846	Transcriptional regulator
DBV13_RS05320	COG1940	carbohydrate kinase activity
DBV13_RS05345	COG1178	ABC-type Fe3 transport system permease component
DBV13_RS05350	COG3842	ATPase activity
DBV13_RS05355	COG1840	ABC-type Fe3 transport system, periplasmic component
DBV13_RS05380	COG4608	Belongs to the ABC transporter superfamily
DBV13_RS05385	COG0444	Belongs to the ABC transporter superfamily
DBV13_RS05390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBV13_RS05405	COG2116	formate transmembrane transporter activity
DBV13_RS05415	COG0242	peptide deformylase activity
DBV13_RS05420	COG1970	mechanosensitive ion channel activity
DBV13_RS05445	COG1846	Transcriptional regulator
DBV13_RS05445	COG0456	acetyltransferase
DBV13_RS05450	COG1780	Probably involved in ribonucleotide reductase function
DBV13_RS05460	COG0431	NADPH-dependent FMN reductase
DBV13_RS05465	COG3226	Transcriptional regulator
DBV13_RS05470	COG0477	Major facilitator Superfamily
DBV13_RS05480	COG1834	amidinotransferase
DBV13_RS05485	COG0549	Belongs to the carbamate kinase family
DBV13_RS05490	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DBV13_RS05510	COG0395	ABC-type sugar transport system, permease component
DBV13_RS05525	COG0366	Alpha amylase catalytic
DBV13_RS05540	COG0477	Major facilitator Superfamily
DBV13_RS05580	COG0012	GTP binding
DBV13_RS05585	COG1322	Protein conserved in bacteria
DBV13_RS05590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DBV13_RS05600	COG1722	exodeoxyribonuclease VII activity
DBV13_RS05605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBV13_RS05610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DBV13_RS05620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DBV13_RS05625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DBV13_RS05630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DBV13_RS05645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DBV13_RS05650	COG1012	belongs to the aldehyde dehydrogenase family
DBV13_RS05665	COG1131	(ABC) transporter
DBV13_RS05670	COG1725	Transcriptional regulator
DBV13_RS05715	COG0148	phosphopyruvate hydratase activity
DBV13_RS05730	COG0193	aminoacyl-tRNA hydrolase activity
DBV13_RS05735	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DBV13_RS05745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DBV13_RS05755	COG1309	transcriptional regulator
DBV13_RS05770	COG4152	abc transporter atp-binding protein
DBV13_RS05775	COG1668	transmembrane transport
DBV13_RS05785	COG0488	(ABC) transporter
DBV13_RS05790	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DBV13_RS05795	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DBV13_RS05805	COG0084	hydrolase, TatD family'
DBV13_RS05810	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DBV13_RS05870	COG1335	isochorismatase
DBV13_RS05890	COG2873	o-acetylhomoserine
DBV13_RS05915	COG1131	(ABC) transporter
DBV13_RS05930	COG2813	Specifically methylates the guanine in position
DBV13_RS05935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DBV13_RS05960	COG1620	l-lactate permease
DBV13_RS05965	COG0247	lactate metabolic process
DBV13_RS05975	COG1556	Lactate utilization protein
DBV13_RS05995	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBV13_RS06000	COG2190	(PTS) system
DBV13_RS06005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DBV13_RS06005	COG1263	PTS System
DBV13_RS06025	COG1051	belongs to the nudix hydrolase family
DBV13_RS06035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DBV13_RS06055	COG1511	domain protein
DBV13_RS06065	COG2848	UPF0210 protein
DBV13_RS06070	COG3830	Belongs to the UPF0237 family
DBV13_RS06085	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DBV13_RS06090	COG0254	rRNA binding
DBV13_RS06095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DBV13_RS06100	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DBV13_RS06105	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DBV13_RS06125	COG0657	acetylesterase activity
DBV13_RS06130	COG2188	Transcriptional regulator
DBV13_RS06135	COG1120	ATPase activity
DBV13_RS06140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBV13_RS06145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBV13_RS06150	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DBV13_RS06165	COG0596	Alpha beta hydrolase
DBV13_RS06185	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DBV13_RS06250	COG1388	LysM domain
DBV13_RS06250	COG0791	NLP P60 protein
DBV13_RS06260	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DBV13_RS06265	COG2252	PERMEase
DBV13_RS06280	COG1278	Cold shock
DBV13_RS06290	COG1842	Phage shock protein A
DBV13_RS06300	COG0745	RESPONSE REGULATOR receiver
DBV13_RS06305	COG2205	protein histidine kinase activity
DBV13_RS06315	COG4221	oxidoreductase activity
DBV13_RS06325	COG0459	protein refolding
DBV13_RS06340	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DBV13_RS06375	COG3842	ATPase activity
DBV13_RS06385	COG0673	inositol 2-dehydrogenase activity
DBV13_RS06395	COG1653	transport
DBV13_RS06400	COG1175	transmembrane transport
DBV13_RS06430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DBV13_RS06445	COG1966	Carbon starvation protein
DBV13_RS06470	COG2233	PERMEase
DBV13_RS06485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DBV13_RS06490	COG0215	cysteine-tRNA ligase activity
DBV13_RS06500	COG1136	(ABC) transporter
DBV13_RS06515	COG2376	Dihydroxyacetone kinase
DBV13_RS06530	COG3775	system Galactitol-specific IIC component
DBV13_RS06560	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DBV13_RS06565	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DBV13_RS06580	COG5002	protein histidine kinase activity
DBV13_RS06590	COG0588	phosphoglycerate mutase activity
DBV13_RS06635	COG1120	ATPase activity
DBV13_RS06640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBV13_RS06675	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DBV13_RS06680	COG0667	Aldo Keto reductase
DBV13_RS06690	COG0710	3-dehydroquinate dehydratase activity
DBV13_RS06720	COG0714	Associated with various cellular activities
DBV13_RS06735	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DBV13_RS06740	COG1950	PFAM Membrane protein of
DBV13_RS06745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DBV13_RS06750	COG0586	Pfam SNARE associated Golgi protein
DBV13_RS06780	COG1309	transcriptional regulator
DBV13_RS06790	COG1132	(ABC) transporter
DBV13_RS06790	COG2375	cellular response to nickel ion
DBV13_RS06795	COG1129	ABC transporter
DBV13_RS06815	COG1609	Transcriptional regulator
DBV13_RS06820	COG2271	Major facilitator Superfamily
DBV13_RS06825	COG0483	inositol monophosphate 1-phosphatase activity
DBV13_RS06830	COG1879	ABC-type sugar transport system periplasmic component
DBV13_RS06835	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBV13_RS06845	COG0673	inositol 2-dehydrogenase activity
DBV13_RS06855	COG0673	inositol 2-dehydrogenase activity
DBV13_RS06860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DBV13_RS06880	COG3718	enzyme involved in inositol metabolism
DBV13_RS06885	COG3962	Belongs to the TPP enzyme family
DBV13_RS06895	COG4604	ABC transporter, ATP-binding protein
DBV13_RS06900	COG4605	iron ion homeostasis
DBV13_RS06905	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBV13_RS06910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DBV13_RS06915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DBV13_RS06920	COG0673	inositol 2-dehydrogenase activity
DBV13_RS06930	COG1175	transmembrane transport
DBV13_RS06935	COG0395	ABC-type sugar transport system, permease component
DBV13_RS06940	COG1063	alcohol dehydrogenase
DBV13_RS06945	COG0156	8-amino-7-oxononanoate synthase activity
DBV13_RS06955	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DBV13_RS06955	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DBV13_RS06960	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DBV13_RS06965	COG1904	glucuronate isomerase
DBV13_RS06980	COG3142	Participates in the control of copper homeostasis
DBV13_RS06995	COG1940	carbohydrate kinase activity
DBV13_RS07005	COG0601	transmembrane transport
DBV13_RS07010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DBV13_RS07020	COG1940	carbohydrate kinase activity
DBV13_RS07025	COG1940	carbohydrate kinase activity
DBV13_RS07025	COG1846	Transcriptional regulator
DBV13_RS07035	COG1175	transmembrane transport
DBV13_RS07105	COG1192	Involved in chromosome partitioning
DBV13_RS07115	COG4974	Belongs to the 'phage' integrase family
DBV13_RS07130	COG1132	(ABC) transporter
DBV13_RS07135	COG2375	cellular response to nickel ion
DBV13_RS07135	COG1132	(ABC) transporter
DBV13_RS07140	COG1129	ABC transporter
DBV13_RS07145	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DBV13_RS07160	COG0471	metal ion transport
DBV13_RS07200	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBV13_RS07210	COG1879	ABC-type sugar transport system periplasmic component
DBV13_RS07220	COG1070	Carbohydrate kinase
DBV13_RS07245	COG1252	NADH dehydrogenase
DBV13_RS07285	COG1643	Atp-dependent helicase
DBV13_RS07300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DBV13_RS07335	COG0577	efflux transmembrane transporter activity
DBV13_RS07340	COG1136	(ABC) transporter
DBV13_RS07355	COG0745	RESPONSE REGULATOR receiver
DBV13_RS07360	COG2205	protein histidine kinase activity
DBV13_RS07365	COG0343	queuine tRNA-ribosyltransferase activity
DBV13_RS07375	COG1428	Deoxynucleoside kinase
DBV13_RS07415	COG0656	L-ascorbic acid biosynthetic process
DBV13_RS07420	COG0351	phosphomethylpyrimidine kinase
DBV13_RS07435	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DBV13_RS07445	COG2814	Major facilitator Superfamily
DBV13_RS07450	COG0305	Participates in initiation and elongation during chromosome replication
DBV13_RS07475	COG0359	binds to the 23S rRNA
DBV13_RS07480	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DBV13_RS07490	COG0360	Binds together with S18 to 16S ribosomal RNA
DBV13_RS07495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DBV13_RS07500	COG0628	permease
DBV13_RS07510	COG0617	tRNA 3'-terminal CCA addition
DBV13_RS07530	COG0492	ferredoxin-NADP+ reductase activity
DBV13_RS07535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBV13_RS07540	COG1181	Belongs to the D-alanine--D-alanine ligase family
DBV13_RS07550	COG1192	Involved in chromosome partitioning
DBV13_RS07555	COG0357	Ribosomal RNA small subunit methyltransferase G
DBV13_RS07565	COG0706	membrane insertase activity
DBV13_RS07570	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DBV13_RS07575	COG0594	ribonuclease P activity
DBV13_RS07580	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DBV13_RS07585	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DBV13_RS07590	COG0592	DNA-directed DNA polymerase activity
DBV13_RS07595	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DBV13_RS07605	COG0187	DNA topoisomerase II activity
DBV13_RS07610	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DBV13_RS07650	COG0705	Rhomboid family
DBV13_RS07650	COG0457	Tetratricopeptide repeat
DBV13_RS07660	COG3764	Sortase (surface protein transpeptidase)
DBV13_RS07685	COG1716	ATPase activity
DBV13_RS07690	COG0842	Transport permease protein
DBV13_RS07690	COG1131	(ABC) transporter
DBV13_RS07690	COG1716	ATPase activity
DBV13_RS07720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DBV13_RS07725	COG1854	S-ribosylhomocysteine lyase activity
DBV13_RS07740	COG1780	Probably involved in ribonucleotide reductase function
DBV13_RS07745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DBV13_RS07750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DBV13_RS07760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DBV13_RS07780	COG0395	ABC-type sugar transport system, permease component
DBV13_RS07785	COG1175	transmembrane transport
DBV13_RS07805	COG2072	flavoprotein involved in K transport
DBV13_RS07815	COG1643	Atp-dependent helicase
DBV13_RS07820	COG2197	response regulator
DBV13_RS07825	COG4585	Histidine kinase
DBV13_RS07835	COG1131	(ABC) transporter
DBV13_RS07845	COG1136	(ABC) transporter
DBV13_RS07855	COG2197	response regulator
DBV13_RS07865	COG1328	CTP reductase activity
DBV13_RS07875	COG2755	lipolytic protein G-D-S-L family
DBV13_RS07875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DBV13_RS07885	COG1136	(ABC) transporter
DBV13_RS07890	COG1414	Transcriptional regulator
DBV13_RS07895	COG0246	Mannitol dehydrogenase
DBV13_RS07900	COG1312	Catalyzes the dehydration of D-mannonate
DBV13_RS07905	COG0800	Aldolase
DBV13_RS07910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBV13_RS07915	COG1120	ATPase activity
DBV13_RS07925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DBV13_RS07930	COG1132	(ABC) transporter
DBV13_RS07935	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DBV13_RS07940	COG1609	Transcriptional regulator
DBV13_RS07955	COG1175	transmembrane transport
DBV13_RS07960	COG0395	ABC-type sugar transport system, permease component
DBV13_RS08020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DBV13_RS08050	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBV13_RS08055	COG1879	ABC-type sugar transport system periplasmic component
DBV13_RS08060	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DBV13_RS08060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DBV13_RS08065	COG1486	melibiose metabolic process
DBV13_RS08130	COG0561	phosphatase activity
DBV13_RS08135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DBV13_RS08150	COG0077	Prephenate dehydratase
DBV13_RS08175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DBV13_RS08195	COG4868	Belongs to the UPF0371 family
DBV13_RS08200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DBV13_RS08250	COG0521	Mo-molybdopterin cofactor biosynthetic process
DBV13_RS08260	COG0315	cyclic pyranopterin monophosphate synthase activity
DBV13_RS08270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DBV13_RS08295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DBV13_RS08325	COG2267	carboxylic ester hydrolase activity
DBV13_RS08370	COG1111	helicase
DBV13_RS08370	COG1205	dead DEAH box helicase
DBV13_RS08375	COG3655	Transcriptional regulator
DBV13_RS08385	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DBV13_RS08385	COG2890	protein-(glutamine-N5) methyltransferase activity
DBV13_RS08390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DBV13_RS08390	COG1754	DNA topoisomerase type I activity
DBV13_RS08395	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DBV13_RS08400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DBV13_RS08465	COG0717	Belongs to the dCTP deaminase family
DBV13_RS08470	COG2111	Na H antiporter
DBV13_RS08470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DBV13_RS08475	COG1006	Multisubunit Na H antiporter MnhC subunit
DBV13_RS08480	COG0651	ATP synthesis coupled electron transport
DBV13_RS08510	COG4149	molybdate abc transporter
DBV13_RS08515	COG3842	ATPase activity
DBV13_RS08530	COG0662	Cupin 2, conserved barrel domain protein
DBV13_RS08570	COG1940	carbohydrate kinase activity
DBV13_RS08575	COG0390	transport system, permease component
DBV13_RS08585	COG1505	serine-type exopeptidase activity
DBV13_RS08595	COG0437	4 iron, 4 sulfur cluster binding
DBV13_RS08600	COG0243	molybdopterin cofactor binding
DBV13_RS08605	COG1937	Protein conserved in bacteria
DBV13_RS08610	COG0446	pyridine nucleotide-disulphide oxidoreductase
DBV13_RS08620	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DBV13_RS08625	COG0540	Belongs to the ATCase OTCase family
DBV13_RS08630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DBV13_RS08635	COG0284	orotidine-5'-phosphate decarboxylase activity
DBV13_RS08640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DBV13_RS08645	COG0167	dihydroorotate dehydrogenase activity
DBV13_RS08650	COG0443	Heat shock 70 kDa protein
DBV13_RS08655	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DBV13_RS08660	COG0484	heat shock protein binding
DBV13_RS08665	COG0789	Transcriptional regulator
DBV13_RS08685	COG0584	glycerophosphoryl diester phosphodiesterase
DBV13_RS08690	COG1506	peptidase
DBV13_RS08690	COG0823	Involved in the tonB-independent uptake of proteins
DBV13_RS08700	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DBV13_RS08730	COG1028	Short-chain dehydrogenase reductase Sdr
DBV13_RS08740	COG0494	nUDIX hydrolase
DBV13_RS08755	COG0191	fructose-bisphosphate aldolase activity
DBV13_RS08765	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DBV13_RS08770	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DBV13_RS08775	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DBV13_RS08780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DBV13_RS08810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DBV13_RS08840	COG0039	L-malate dehydrogenase activity
DBV13_RS08845	COG0728	peptidoglycan biosynthetic process
DBV13_RS08870	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DBV13_RS08895	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DBV13_RS08900	COG0494	nUDIX hydrolase
DBV13_RS08900	COG0406	alpha-ribazole phosphatase activity
DBV13_RS08920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DBV13_RS08925	COG0306	phosphate transporter
DBV13_RS08935	COG1115	amino acid carrier protein
DBV13_RS08945	COG0737	Belongs to the 5'-nucleotidase family
DBV13_RS08955	COG3485	protocatechuate 3,4-dioxygenase
DBV13_RS08960	COG0354	folic acid binding
DBV13_RS08970	COG1490	D-aminoacyl-tRNA deacylase activity
DBV13_RS08990	COG0738	Major facilitator superfamily
DBV13_RS08995	COG2390	Transcriptional regulator
DBV13_RS09015	COG1349	DNA-binding transcription factor activity
DBV13_RS09035	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DBV13_RS09040	COG2376	Dihydroxyacetone kinase
DBV13_RS09050	COG0698	ribose 5-phosphate isomerase
DBV13_RS09055	COG0730	response to heat
DBV13_RS09060	COG0641	radical SAM
DBV13_RS09065	COG2271	Major facilitator Superfamily
DBV13_RS09070	COG1609	Transcriptional regulator
DBV13_RS09075	COG3119	arylsulfatase activity
DBV13_RS09090	COG0395	ABC-type sugar transport system, permease component
DBV13_RS09105	COG1501	Belongs to the glycosyl hydrolase 31 family
DBV13_RS09115	COG1349	DNA-binding transcription factor activity
DBV13_RS09125	COG1175	transmembrane transport
DBV13_RS09130	COG0395	ABC-type sugar transport system, permease component
DBV13_RS09155	COG2115	Belongs to the xylose isomerase family
DBV13_RS09160	COG1070	Carbohydrate kinase
DBV13_RS09165	COG4213	ABC transporter substrate-binding protein
DBV13_RS09175	COG4214	carbohydrate transport
DBV13_RS09180	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DBV13_RS09185	COG1757	Na H antiporter
DBV13_RS09195	COG3250	beta-galactosidase activity
DBV13_RS09205	COG0395	ABC-type sugar transport system, permease component
DBV13_RS09215	COG1609	Transcriptional regulator
DBV13_RS09225	COG0395	ABC-type sugar transport system, permease component
DBV13_RS09230	COG1175	transmembrane transport
DBV13_RS09245	COG3250	beta-galactosidase activity
DBV13_RS09255	COG1609	Transcriptional regulator
DBV13_RS09260	COG2610	gluconate transmembrane transporter activity
DBV13_RS09270	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DBV13_RS09280	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DBV13_RS09285	COG3250	beta-galactosidase activity
DBV13_RS09290	COG1869	D-ribose catabolic process
DBV13_RS09295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBV13_RS09300	COG1879	ABC-type sugar transport system periplasmic component
DBV13_RS09305	COG1172	Belongs to the binding-protein-dependent transport system permease family
DBV13_RS09310	COG1129	ABC transporter
DBV13_RS09315	COG1609	Transcriptional regulator
DBV13_RS09320	COG2226	methyltransferase
DBV13_RS09325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DBV13_RS09325	COG1116	anion transmembrane transporter activity
DBV13_RS09345	COG0737	Belongs to the 5'-nucleotidase family
DBV13_RS09355	COG1609	Transcriptional regulator
DBV13_RS09360	COG2271	Major facilitator Superfamily
DBV13_RS09365	COG1285	pathogenesis
DBV13_RS09375	COG5564	TIM-barrel signal transduction protein
DBV13_RS09385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBV13_RS09400	COG1397	ADP-ribosylglycohydrolase
DBV13_RS09405	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DBV13_RS09410	COG1122	ATPase activity
DBV13_RS09445	COG1131	(ABC) transporter
DBV13_RS09460	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DBV13_RS09555	COG1518	maintenance of DNA repeat elements
DBV13_RS09570	COG3609	addiction module antidote protein, CC2985 family
DBV13_RS09585	COG0366	Alpha amylase catalytic
DBV13_RS09590	COG0395	ABC-type sugar transport system, permease component
DBV13_RS09595	COG1175	transmembrane transport
DBV13_RS09610	COG0574	Belongs to the PEP-utilizing enzyme family
DBV13_RS09610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DBV13_RS09615	COG0247	lactate metabolic process
DBV13_RS09615	COG0277	FAD linked oxidase domain protein
DBV13_RS09625	COG2267	carboxylic ester hydrolase activity
DBV13_RS09630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DBV13_RS09635	COG0791	NLP P60 protein
DBV13_RS09640	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DBV13_RS09655	COG0037	tRNA processing
DBV13_RS09665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DBV13_RS09670	COG0302	gtp cyclohydrolase
DBV13_RS09680	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DBV13_RS09700	COG1609	Transcriptional regulator
DBV13_RS09720	COG3250	beta-galactosidase activity
DBV13_RS09730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DBV13_RS09730	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DBV13_RS09735	COG1461	Dihydroxyacetone kinase
DBV13_RS09740	COG2376	Dihydroxyacetone kinase
DBV13_RS09750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DBV13_RS09755	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DBV13_RS09765	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DBV13_RS09770	COG2409	Drug exporters of the RND superfamily
DBV13_RS09775	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DBV13_RS09780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DBV13_RS09790	COG3386	PFAM SMP-30 Gluconolaconase
DBV13_RS09795	COG0247	lactate metabolic process
DBV13_RS09800	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
DBV13_RS09805	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DBV13_RS09820	COG1194	a g-specific adenine glycosylase
DBV13_RS09830	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DBV13_RS09835	COG0569	domain protein
DBV13_RS09840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DBV13_RS09855	COG1846	Transcriptional regulator
DBV13_RS09860	COG0406	alpha-ribazole phosphatase activity
DBV13_RS09885	COG0395	ABC-type sugar transport system, permease component
DBV13_RS09890	COG1177	transmembrane transport
DBV13_RS09900	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DBV13_RS09905	COG4948	Mandelate Racemase Muconate Lactonizing
DBV13_RS09910	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DBV13_RS09915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DBV13_RS09920	COG1169	isochorismate synthase
DBV13_RS09925	COG2226	methyltransferase
DBV13_RS09930	COG0644	oxidoreductase
DBV13_RS09940	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DBV13_RS09945	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DBV13_RS09950	COG0649	NAD binding
DBV13_RS09960	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DBV13_RS09965	COG1034	ATP synthesis coupled electron transport
DBV13_RS09970	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DBV13_RS09975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DBV13_RS09980	COG0839	Belongs to the complex I subunit 6 family
DBV13_RS09985	COG0713	ATP synthesis coupled electron transport
DBV13_RS10000	COG1007	ATP synthesis coupled electron transport
DBV13_RS10005	COG0142	geranyltranstransferase activity
DBV13_RS10010	COG0653	protein targeting
DBV13_RS10050	COG0419	ATPase involved in DNA repair
DBV13_RS10055	COG0420	3'-5' exonuclease activity
DBV13_RS10060	COG0483	inositol monophosphate 1-phosphatase activity
DBV13_RS10065	COG1162	GTPase activity
DBV13_RS10070	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DBV13_RS10105	COG0657	acetylesterase activity
DBV13_RS10120	COG0601	transmembrane transport
DBV13_RS10125	COG0444	Belongs to the ABC transporter superfamily
DBV13_RS10130	COG4608	Belongs to the ABC transporter superfamily
DBV13_RS10135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DBV13_RS10145	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DBV13_RS10150	COG0363	glucosamine-6-phosphate deaminase activity
DBV13_RS10160	COG1595	DNA-templated transcription, initiation
DBV13_RS10185	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DBV13_RS10205	COG3103	Sh3 type 3 domain protein
DBV13_RS10205	COG1388	LysM domain
DBV13_RS10205	COG0791	NLP P60 protein
DBV13_RS10215	COG0508	dehydrogenase complex catalyzes the overall conversion of
DBV13_RS10215	COG0567	Dehydrogenase, E1 component
DBV13_RS10220	COG1253	flavin adenine dinucleotide binding
DBV13_RS10230	COG0739	heme binding
DBV13_RS10235	COG0584	glycerophosphoryl diester phosphodiesterase
DBV13_RS10280	COG0018	arginyl-trna synthetase
DBV13_RS10290	COG0460	homoserine dehydrogenase
DBV13_RS10295	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DBV13_RS10300	COG0083	homoserine kinase activity
DBV13_RS10315	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DBV13_RS10330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DBV13_RS10340	COG0356	it plays a direct role in the translocation of protons across the membrane
DBV13_RS10345	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DBV13_RS10350	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DBV13_RS10355	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DBV13_RS10360	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DBV13_RS10365	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DBV13_RS10370	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DBV13_RS10375	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DBV13_RS10385	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DBV13_RS10430	COG1609	Transcriptional regulator
DBV13_RS10440	COG1175	transmembrane transport
DBV13_RS10445	COG3833	ABC-type maltose transport systems, permease component
DBV13_RS10455	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DBV13_RS10460	COG3281	Trehalose synthase
DBV13_RS10465	COG0366	Alpha amylase catalytic
DBV13_RS10470	COG0366	Alpha amylase catalytic
DBV13_RS10495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DBV13_RS10500	COG0058	SHG alpha-glucan phosphorylase activity
DBV13_RS10505	COG0180	Tryptophanyl-tRNA synthetase
DBV13_RS10535	COG3480	Lon protease (S16) C-terminal proteolytic domain
DBV13_RS10545	COG1615	UPF0182 protein
DBV13_RS10550	COG0366	Alpha amylase catalytic
DBV13_RS10550	COG1470	cell adhesion involved in biofilm formation
DBV13_RS10570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DBV13_RS10575	COG1131	(ABC) transporter
DBV13_RS10585	COG0387	Pfam Sodium calcium exchanger
DBV13_RS10595	COG1053	succinate dehydrogenase
DBV13_RS10620	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DBV13_RS10655	COG4585	Histidine kinase
DBV13_RS10660	COG2135	peptidase activity
DBV13_RS10665	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DBV13_RS10675	COG1397	ADP-ribosylglycohydrolase
DBV13_RS10685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DBV13_RS10695	COG1404	Belongs to the peptidase S8 family
DBV13_RS10700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DBV13_RS10705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DBV13_RS10710	COG0154	amidase activity
DBV13_RS10715	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)