locus-tag	class	description
DDE06_RS00010	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DDE06_RS00045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DDE06_RS00050	COG1381	Involved in DNA repair and RecF pathway recombination
DDE06_RS00055	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDE06_RS00060	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DDE06_RS00070	COG0131	Imidazoleglycerol-phosphate dehydratase
DDE06_RS00080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DDE06_RS00085	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DDE06_RS00095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DDE06_RS00100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DDE06_RS00115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDE06_RS00135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DDE06_RS00140	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DDE06_RS00155	COG1438	arginine binding
DDE06_RS00160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DDE06_RS00170	COG1476	TRANSCRIPTIONal
DDE06_RS00180	COG1131	(ABC) transporter
DDE06_RS00185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DDE06_RS00190	COG0803	Belongs to the bacterial solute-binding protein 9 family
DDE06_RS00195	COG1121	(ABC) transporter
DDE06_RS00200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDE06_RS00205	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDE06_RS00235	COG0647	UMP catabolic process
DDE06_RS00245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DDE06_RS00250	COG0497	DNA recombination
DDE06_RS00270	COG0728	peptidoglycan biosynthetic process
DDE06_RS00300	COG0396	ATPase activity
DDE06_RS00315	COG2151	metal-sulfur cluster biosynthetic enzyme
DDE06_RS00320	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DDE06_RS00325	COG0488	(ABC) transporter
DDE06_RS00335	COG3830	Belongs to the UPF0237 family
DDE06_RS00335	COG0560	Phosphoserine phosphatase
DDE06_RS00345	COG1136	(ABC) transporter
DDE06_RS00355	COG0297	glycogen (starch) synthase activity
DDE06_RS00360	COG1119	ATPase activity
DDE06_RS00395	COG1881	PFAM PEBP family protein
DDE06_RS00410	COG0587	DNA-directed DNA polymerase activity
DDE06_RS00435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DDE06_RS00435	COG0519	Catalyzes the synthesis of GMP from XMP
DDE06_RS00445	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDE06_RS00460	COG1968	undecaprenyl-diphosphatase activity
DDE06_RS00480	COG1222	aaa ATPase
DDE06_RS00485	COG4122	O-methyltransferase activity
DDE06_RS00495	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DDE06_RS00510	COG0107	imidazoleglycerol-phosphate synthase activity
DDE06_RS00520	COG0134	indole-3-glycerol-phosphate synthase activity
DDE06_RS00525	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DDE06_RS00530	COG0469	pyruvate kinase activity
DDE06_RS00555	COG0539	negative regulation of cytoplasmic translation
DDE06_RS00565	COG1136	(ABC) transporter
DDE06_RS00570	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DDE06_RS00575	COG0237	dephospho-CoA kinase activity
DDE06_RS00580	COG0556	nucleotide-excision repair
DDE06_RS00605	COG0322	excinuclease ABC activity
DDE06_RS00610	COG1660	Displays ATPase and GTPase activities
DDE06_RS00620	COG1481	regulation of sporulation
DDE06_RS00625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DDE06_RS00630	COG0126	phosphoglycerate kinase activity
DDE06_RS00635	COG0149	triose-phosphate isomerase activity
DDE06_RS00640	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DDE06_RS00655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DDE06_RS00680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DDE06_RS00695	COG1160	GTP binding
DDE06_RS00700	COG0205	6-phosphofructokinase activity
DDE06_RS00745	COG1216	Glycosyl transferase, family 2
DDE06_RS00755	COG4581	dead DEAH box helicase
DDE06_RS00785	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DDE06_RS00790	COG0140	phosphoribosyl-ATP diphosphatase activity
DDE06_RS00795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DDE06_RS00800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DDE06_RS00805	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DDE06_RS00815	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DDE06_RS00820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DDE06_RS00825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DDE06_RS00835	COG1758	RNA polymerase activity
DDE06_RS00840	COG0194	GDP metabolic process
DDE06_RS00850	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DDE06_RS00855	COG0505	Belongs to the CarA family
DDE06_RS00860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DDE06_RS00865	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DDE06_RS00870	COG2217	Heavy metal translocating P-type atpase
DDE06_RS00875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DDE06_RS00885	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DDE06_RS00905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DDE06_RS00910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DDE06_RS00920	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DDE06_RS00930	COG2409	Drug exporters of the RND superfamily
DDE06_RS00945	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DDE06_RS00965	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DDE06_RS00970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DDE06_RS00975	COG0124	histidyl-tRNA synthetase
DDE06_RS00980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDE06_RS00985	COG1196	nuclear chromosome segregation
DDE06_RS00995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DDE06_RS01000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDE06_RS01005	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDE06_RS01010	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DDE06_RS01020	COG2255	four-way junction helicase activity
DDE06_RS01025	COG0632	four-way junction helicase activity
DDE06_RS01030	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DDE06_RS01035	COG0217	transcriptional regulatory protein
DDE06_RS01040	COG1051	belongs to the nudix hydrolase family
DDE06_RS01050	COG0438	transferase activity, transferring glycosyl groups
DDE06_RS01060	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DDE06_RS01065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DDE06_RS01070	COG1760	l-serine dehydratase
DDE06_RS01075	COG2197	response regulator
DDE06_RS01095	COG4412	M6 family metalloprotease domain protein
DDE06_RS01095	COG1404	Belongs to the peptidase S8 family
DDE06_RS01145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DDE06_RS01155	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DDE06_RS01170	COG0569	domain protein
DDE06_RS01215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DDE06_RS01230	COG0187	DNA topoisomerase II activity
DDE06_RS01240	COG1199	ATP-dependent helicase activity
DDE06_RS01240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DDE06_RS01245	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DDE06_RS01260	COG0142	geranyltranstransferase activity
DDE06_RS01275	COG0515	serine threonine protein kinase
DDE06_RS01275	COG2815	serine threonine protein kinase
DDE06_RS01280	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
DDE06_RS01285	COG0205	6-phosphofructokinase activity
DDE06_RS01325	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DDE06_RS01340	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DDE06_RS01350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDE06_RS01355	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDE06_RS01375	COG0174	glutamine synthetase
DDE06_RS01385	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DDE06_RS01390	COG0174	glutamine synthetase
DDE06_RS01405	COG1940	carbohydrate kinase activity
DDE06_RS01415	COG3022	response to hydroperoxide
DDE06_RS01425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DDE06_RS01430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DDE06_RS01435	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DDE06_RS01460	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DDE06_RS01480	COG0009	L-threonylcarbamoyladenylate synthase
DDE06_RS01500	COG1090	epimerase
DDE06_RS01535	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DDE06_RS01540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDE06_RS01575	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DDE06_RS01580	COG0805	protein transport
DDE06_RS01590	COG0358	DNA primase activity
DDE06_RS01615	COG0423	glycine-tRNA ligase activity
DDE06_RS01625	COG1121	(ABC) transporter
DDE06_RS01630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDE06_RS01635	COG0735	belongs to the Fur family
DDE06_RS01650	COG0587	DNA-directed DNA polymerase activity
DDE06_RS01665	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DDE06_RS01680	COG1799	cell septum assembly
DDE06_RS01690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DDE06_RS01700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DDE06_RS01705	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DDE06_RS01710	COG0772	Belongs to the SEDS family
DDE06_RS01715	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DDE06_RS01720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DDE06_RS01725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DDE06_RS01730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DDE06_RS01735	COG0768	penicillin binding
DDE06_RS01745	COG0275	rRNA processing
DDE06_RS01750	COG2001	Belongs to the MraZ family
DDE06_RS01760	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DDE06_RS01780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DDE06_RS01785	COG0318	PFAM AMP-dependent synthetase and ligase
DDE06_RS01790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DDE06_RS01800	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DDE06_RS01810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DDE06_RS01820	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DDE06_RS01825	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DDE06_RS01830	COG2137	regulation of response to DNA damage stimulus
DDE06_RS01835	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DDE06_RS01845	COG1396	sequence-specific DNA binding
DDE06_RS01850	COG1058	Belongs to the CinA family
DDE06_RS01850	COG1546	Belongs to the CinA family
DDE06_RS01865	COG1674	ftsk spoiiie
DDE06_RS01870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DDE06_RS01885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DDE06_RS01890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DDE06_RS01895	COG0612	Peptidase, M16
DDE06_RS01905	COG1185	polyribonucleotide nucleotidyltransferase activity
DDE06_RS01950	COG3842	ATPase activity
DDE06_RS01960	COG2271	Major facilitator Superfamily
DDE06_RS01965	COG0745	RESPONSE REGULATOR receiver
DDE06_RS01970	COG3852	Histidine kinase
DDE06_RS01975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DDE06_RS01980	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DDE06_RS01985	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DDE06_RS02000	COG0779	Required for maturation of 30S ribosomal subunits
DDE06_RS02010	COG0442	prolyl-tRNA aminoacylation
DDE06_RS02020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DDE06_RS02025	COG0750	zinc metalloprotease
DDE06_RS02030	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DDE06_RS02040	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DDE06_RS02050	COG0233	cytoplasmic translational termination
DDE06_RS02075	COG0644	oxidoreductase
DDE06_RS02080	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DDE06_RS02090	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DDE06_RS02095	COG0052	Belongs to the universal ribosomal protein uS2 family
DDE06_RS02100	COG2860	membrane
DDE06_RS02105	COG4942	peptidase
DDE06_RS02105	COG1388	LysM domain
DDE06_RS02110	COG4974	Belongs to the 'phage' integrase family
DDE06_RS02135	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DDE06_RS02140	COG0681	Belongs to the peptidase S26 family
DDE06_RS02145	COG0335	large ribosomal subunit rRNA binding
DDE06_RS02155	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DDE06_RS02160	COG1837	Belongs to the UPF0109 family
DDE06_RS02165	COG0228	four-way junction DNA binding
DDE06_RS02170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DDE06_RS02210	COG0105	UTP biosynthetic process
DDE06_RS02215	COG0285	dihydrofolate synthase activity
DDE06_RS02220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DDE06_RS02235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DDE06_RS02255	COG0287	Prephenate dehydrogenase
DDE06_RS02255	COG1605	Chorismate mutase
DDE06_RS02260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DDE06_RS02265	COG0740	serine-type endopeptidase activity
DDE06_RS02270	COG0740	serine-type endopeptidase activity
DDE06_RS02275	COG0544	peptidyl-prolyl cis-trans isomerase activity
DDE06_RS02280	COG0667	Aldo Keto reductase
DDE06_RS02300	COG3250	beta-galactosidase activity
DDE06_RS02305	COG1609	Transcriptional regulator
DDE06_RS02320	COG0488	(ABC) transporter
DDE06_RS02335	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DDE06_RS02350	COG1739	Uncharacterized protein family UPF0029
DDE06_RS02360	COG1045	serine acetyltransferase
DDE06_RS02375	COG3590	peptidase
DDE06_RS02380	COG2354	Protein conserved in bacteria
DDE06_RS02390	COG0519	Catalyzes the synthesis of GMP from XMP
DDE06_RS02435	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DDE06_RS02465	COG0463	Glycosyl transferase, family 2
DDE06_RS02470	COG2244	polysaccharide biosynthetic process
DDE06_RS02495	COG1442	glycosyl transferase family 8
DDE06_RS02495	COG1216	Glycosyl transferase, family 2
DDE06_RS02500	COG3475	LICD family
DDE06_RS02505	COG4750	Nucleotidyl transferase
DDE06_RS02510	COG0438	transferase activity, transferring glycosyl groups
DDE06_RS02540	COG1882	Formate acetyltransferase
DDE06_RS02550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DDE06_RS02555	COG0473	3-isopropylmalate dehydrogenase activity
DDE06_RS02570	COG1027	Aspartate ammonia-lyase
DDE06_RS02580	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DDE06_RS02585	COG0440	acetolactate synthase activity
DDE06_RS02595	COG0569	domain protein
DDE06_RS02595	COG2985	domain, Protein
DDE06_RS02600	COG0129	dihydroxy-acid dehydratase activity
DDE06_RS02650	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DDE06_RS02655	COG0154	amidase activity
DDE06_RS02660	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DDE06_RS02665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DDE06_RS02670	COG1404	Belongs to the peptidase S8 family
DDE06_RS02680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDE06_RS02690	COG1397	ADP-ribosylglycohydrolase
DDE06_RS02700	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DDE06_RS02705	COG2135	peptidase activity
DDE06_RS02710	COG4585	Histidine kinase
DDE06_RS02745	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DDE06_RS02770	COG1053	succinate dehydrogenase
DDE06_RS02780	COG0387	Pfam Sodium calcium exchanger
DDE06_RS02790	COG1131	(ABC) transporter
DDE06_RS02795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDE06_RS02815	COG1470	cell adhesion involved in biofilm formation
DDE06_RS02815	COG0366	Alpha amylase catalytic
DDE06_RS02820	COG1615	UPF0182 protein
DDE06_RS02830	COG3480	Lon protease (S16) C-terminal proteolytic domain
DDE06_RS02860	COG0180	Tryptophanyl-tRNA synthetase
DDE06_RS02865	COG0058	SHG alpha-glucan phosphorylase activity
DDE06_RS02870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DDE06_RS02895	COG0366	Alpha amylase catalytic
DDE06_RS02900	COG0366	Alpha amylase catalytic
DDE06_RS02905	COG3281	Trehalose synthase
DDE06_RS02910	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DDE06_RS02925	COG3833	ABC-type maltose transport systems, permease component
DDE06_RS02930	COG1175	transmembrane transport
DDE06_RS02940	COG1609	Transcriptional regulator
DDE06_RS02985	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DDE06_RS02995	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DDE06_RS03000	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DDE06_RS03005	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DDE06_RS03010	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DDE06_RS03015	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDE06_RS03020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DDE06_RS03025	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DDE06_RS03030	COG0356	it plays a direct role in the translocation of protons across the membrane
DDE06_RS03055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DDE06_RS03070	COG0083	homoserine kinase activity
DDE06_RS03075	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DDE06_RS03080	COG0460	homoserine dehydrogenase
DDE06_RS03090	COG0018	arginyl-trna synthetase
DDE06_RS03130	COG0584	glycerophosphoryl diester phosphodiesterase
DDE06_RS03135	COG0739	heme binding
DDE06_RS03145	COG1253	flavin adenine dinucleotide binding
DDE06_RS03150	COG0508	dehydrogenase complex catalyzes the overall conversion of
DDE06_RS03150	COG0567	Dehydrogenase, E1 component
DDE06_RS03160	COG3103	Sh3 type 3 domain protein
DDE06_RS03160	COG0791	NLP P60 protein
DDE06_RS03160	COG1388	LysM domain
DDE06_RS03175	COG1595	DNA-templated transcription, initiation
DDE06_RS03185	COG0363	glucosamine-6-phosphate deaminase activity
DDE06_RS03190	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DDE06_RS03200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DDE06_RS03205	COG4608	Belongs to the ABC transporter superfamily
DDE06_RS03210	COG0444	Belongs to the ABC transporter superfamily
DDE06_RS03215	COG0601	transmembrane transport
DDE06_RS03230	COG0657	acetylesterase activity
DDE06_RS03255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DDE06_RS03260	COG1162	GTPase activity
DDE06_RS03265	COG0483	inositol monophosphate 1-phosphatase activity
DDE06_RS03270	COG0420	3'-5' exonuclease activity
DDE06_RS03275	COG0419	ATPase involved in DNA repair
DDE06_RS03315	COG0653	protein targeting
DDE06_RS03320	COG0142	geranyltranstransferase activity
DDE06_RS03325	COG1007	ATP synthesis coupled electron transport
DDE06_RS03335	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DDE06_RS03340	COG0713	ATP synthesis coupled electron transport
DDE06_RS03345	COG0839	Belongs to the complex I subunit 6 family
DDE06_RS03350	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDE06_RS03355	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DDE06_RS03360	COG1034	ATP synthesis coupled electron transport
DDE06_RS03365	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DDE06_RS03375	COG0649	NAD binding
DDE06_RS03380	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDE06_RS03385	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DDE06_RS03395	COG0644	oxidoreductase
DDE06_RS03400	COG2226	methyltransferase
DDE06_RS03405	COG1169	isochorismate synthase
DDE06_RS03410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DDE06_RS03415	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DDE06_RS03420	COG4948	Mandelate Racemase Muconate Lactonizing
DDE06_RS03425	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DDE06_RS03435	COG1175	transmembrane transport
DDE06_RS03440	COG0395	ABC-type sugar transport system, permease component
DDE06_RS03465	COG0406	alpha-ribazole phosphatase activity
DDE06_RS03470	COG1846	Transcriptional regulator
DDE06_RS03485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DDE06_RS03490	COG0569	domain protein
DDE06_RS03495	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DDE06_RS03505	COG1194	a g-specific adenine glycosylase
DDE06_RS03520	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DDE06_RS03525	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
DDE06_RS03530	COG0247	lactate metabolic process
DDE06_RS03535	COG3386	PFAM SMP-30 Gluconolaconase
DDE06_RS03545	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DDE06_RS03550	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DDE06_RS03555	COG2409	Drug exporters of the RND superfamily
DDE06_RS03560	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DDE06_RS03570	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DDE06_RS03575	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DDE06_RS03585	COG2376	Dihydroxyacetone kinase
DDE06_RS03590	COG1461	Dihydroxyacetone kinase
DDE06_RS03595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDE06_RS03595	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDE06_RS03605	COG3250	beta-galactosidase activity
DDE06_RS03625	COG1609	Transcriptional regulator
DDE06_RS03655	COG0302	gtp cyclohydrolase
DDE06_RS03660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DDE06_RS03670	COG0037	tRNA processing
DDE06_RS03685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DDE06_RS03690	COG0791	NLP P60 protein
DDE06_RS03695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DDE06_RS03700	COG2267	carboxylic ester hydrolase activity
DDE06_RS03710	COG0247	lactate metabolic process
DDE06_RS03710	COG0277	FAD linked oxidase domain protein
DDE06_RS03715	COG0574	Belongs to the PEP-utilizing enzyme family
DDE06_RS03715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDE06_RS03730	COG1175	transmembrane transport
DDE06_RS03735	COG0395	ABC-type sugar transport system, permease component
DDE06_RS03740	COG0366	Alpha amylase catalytic
DDE06_RS03755	COG3609	addiction module antidote protein, CC2985 family
DDE06_RS03770	COG1518	maintenance of DNA repeat elements
DDE06_RS03850	COG1122	ATPase activity
DDE06_RS03855	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DDE06_RS03860	COG1397	ADP-ribosylglycohydrolase
DDE06_RS03880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDE06_RS03890	COG5564	TIM-barrel signal transduction protein
DDE06_RS03895	COG1285	pathogenesis
DDE06_RS03900	COG2271	Major facilitator Superfamily
DDE06_RS03905	COG1609	Transcriptional regulator
DDE06_RS03920	COG0737	Belongs to the 5'-nucleotidase family
DDE06_RS03940	COG1116	anion transmembrane transporter activity
DDE06_RS03945	COG2226	methyltransferase
DDE06_RS03950	COG1609	Transcriptional regulator
DDE06_RS03955	COG1129	ABC transporter
DDE06_RS03960	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDE06_RS03965	COG1879	ABC-type sugar transport system periplasmic component
DDE06_RS03970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDE06_RS03990	COG1869	D-ribose catabolic process
DDE06_RS03995	COG3250	beta-galactosidase activity
DDE06_RS04000	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DDE06_RS04020	COG2610	gluconate transmembrane transporter activity
DDE06_RS04025	COG1609	Transcriptional regulator
DDE06_RS04035	COG3250	beta-galactosidase activity
DDE06_RS04050	COG1175	transmembrane transport
DDE06_RS04055	COG0395	ABC-type sugar transport system, permease component
DDE06_RS04065	COG1609	Transcriptional regulator
DDE06_RS04075	COG0395	ABC-type sugar transport system, permease component
DDE06_RS04085	COG3250	beta-galactosidase activity
DDE06_RS04095	COG1757	Na H antiporter
DDE06_RS04100	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DDE06_RS04105	COG4214	carbohydrate transport
DDE06_RS04115	COG4213	ABC transporter substrate-binding protein
DDE06_RS04120	COG1070	Carbohydrate kinase
DDE06_RS04125	COG2115	Belongs to the xylose isomerase family
DDE06_RS04155	COG0395	ABC-type sugar transport system, permease component
DDE06_RS04160	COG1175	transmembrane transport
DDE06_RS04170	COG1349	DNA-binding transcription factor activity
DDE06_RS04180	COG1501	Belongs to the glycosyl hydrolase 31 family
DDE06_RS04195	COG0395	ABC-type sugar transport system, permease component
DDE06_RS04205	COG3119	arylsulfatase activity
DDE06_RS04210	COG1609	Transcriptional regulator
DDE06_RS04215	COG2814	Major facilitator Superfamily
DDE06_RS04220	COG0641	radical SAM
DDE06_RS04225	COG0730	response to heat
DDE06_RS04230	COG0698	ribose 5-phosphate isomerase
DDE06_RS04240	COG2376	Dihydroxyacetone kinase
DDE06_RS04245	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DDE06_RS04265	COG1349	DNA-binding transcription factor activity
DDE06_RS04290	COG0738	Major facilitator superfamily
DDE06_RS04310	COG1490	D-aminoacyl-tRNA deacylase activity
DDE06_RS04320	COG0354	folic acid binding
DDE06_RS04325	COG3485	protocatechuate 3,4-dioxygenase
DDE06_RS04335	COG0737	Belongs to the 5'-nucleotidase family
DDE06_RS04345	COG1115	amino acid carrier protein
DDE06_RS04355	COG0306	phosphate transporter
DDE06_RS04360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DDE06_RS04380	COG0406	alpha-ribazole phosphatase activity
DDE06_RS04380	COG0494	nUDIX hydrolase
DDE06_RS04385	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DDE06_RS04445	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDE06_RS04445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DDE06_RS04500	COG0270	DNA (cytosine-5-)-methyltransferase activity
DDE06_RS04525	COG1802	Transcriptional regulator
DDE06_RS04525	COG4626	Terminase
DDE06_RS04535	COG4695	Portal protein
DDE06_RS04570	COG1715	Restriction endonuclease
DDE06_RS04670	COG4824	toxin secretion phage lysis holin
DDE06_RS04730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DDE06_RS04755	COG0728	peptidoglycan biosynthetic process
DDE06_RS04760	COG0039	L-malate dehydrogenase activity
DDE06_RS04790	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DDE06_RS04820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DDE06_RS04825	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DDE06_RS04830	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DDE06_RS04835	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DDE06_RS04845	COG0191	fructose-bisphosphate aldolase activity
DDE06_RS04860	COG0494	nUDIX hydrolase
DDE06_RS04875	COG1028	Short-chain dehydrogenase reductase Sdr
DDE06_RS04905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DDE06_RS04915	COG1506	peptidase
DDE06_RS04915	COG0823	Involved in the tonB-independent uptake of proteins
DDE06_RS04925	COG0584	glycerophosphoryl diester phosphodiesterase
DDE06_RS04950	COG0484	heat shock protein binding
DDE06_RS04955	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DDE06_RS04960	COG0443	Heat shock 70 kDa protein
DDE06_RS04970	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DDE06_RS04975	COG0284	orotidine-5'-phosphate decarboxylase activity
DDE06_RS04980	COG0540	Belongs to the ATCase OTCase family
DDE06_RS04985	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DDE06_RS04995	COG0243	molybdopterin cofactor binding
DDE06_RS05000	COG0437	4 iron, 4 sulfur cluster binding
DDE06_RS05010	COG0446	pyridine nucleotide-disulphide oxidoreductase
DDE06_RS05015	COG1937	Protein conserved in bacteria
DDE06_RS05020	COG0243	molybdopterin cofactor binding
DDE06_RS05025	COG0437	4 iron, 4 sulfur cluster binding
DDE06_RS05035	COG1505	serine-type exopeptidase activity
DDE06_RS05045	COG0390	transport system, permease component
DDE06_RS05050	COG1940	carbohydrate kinase activity
DDE06_RS05075	COG0662	Cupin 2, conserved barrel domain protein
DDE06_RS05095	COG3842	ATPase activity
DDE06_RS05100	COG4149	molybdate abc transporter
DDE06_RS05130	COG0651	ATP synthesis coupled electron transport
DDE06_RS05135	COG1006	Multisubunit Na H antiporter MnhC subunit
DDE06_RS05140	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DDE06_RS05140	COG2111	Na H antiporter
DDE06_RS05145	COG0717	Belongs to the dCTP deaminase family
DDE06_RS05190	COG2801	Transposase and inactivated derivatives
DDE06_RS05220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DDE06_RS05225	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DDE06_RS05230	COG1754	DNA topoisomerase type I activity
DDE06_RS05230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DDE06_RS05235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DDE06_RS05235	COG2890	protein-(glutamine-N5) methyltransferase activity
DDE06_RS05245	COG3655	Transcriptional regulator
DDE06_RS05295	COG0596	Alpha beta hydrolase
DDE06_RS05325	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDE06_RS05350	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DDE06_RS05360	COG0315	cyclic pyranopterin monophosphate synthase activity
DDE06_RS05370	COG0521	Mo-molybdopterin cofactor biosynthetic process
DDE06_RS05420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DDE06_RS05425	COG4868	Belongs to the UPF0371 family
DDE06_RS05445	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DDE06_RS05470	COG0077	Prephenate dehydratase
DDE06_RS05480	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DDE06_RS05485	COG0561	phosphatase activity
DDE06_RS05515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDE06_RS05520	COG1879	ABC-type sugar transport system periplasmic component
DDE06_RS05525	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDE06_RS05555	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DDE06_RS05640	COG1487	ribonuclease activity
DDE06_RS05645	COG0732	type I restriction modification DNA specificity domain
DDE06_RS05675	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
DDE06_RS05685	COG0395	ABC-type sugar transport system, permease component
DDE06_RS05690	COG1175	transmembrane transport
DDE06_RS05705	COG1609	Transcriptional regulator
DDE06_RS05710	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DDE06_RS05715	COG1132	(ABC) transporter
DDE06_RS05730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDE06_RS05740	COG1120	ATPase activity
DDE06_RS05750	COG2226	methyltransferase
DDE06_RS05755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDE06_RS05760	COG0800	Aldolase
DDE06_RS05765	COG1312	Catalyzes the dehydration of D-mannonate
DDE06_RS05770	COG0246	Mannitol dehydrogenase
DDE06_RS05775	COG1414	Transcriptional regulator
DDE06_RS05780	COG1136	(ABC) transporter
DDE06_RS05800	COG1328	CTP reductase activity
DDE06_RS05810	COG2197	response regulator
DDE06_RS05820	COG1136	(ABC) transporter
DDE06_RS05830	COG1131	(ABC) transporter
DDE06_RS05840	COG4585	Histidine kinase
DDE06_RS05845	COG2197	response regulator
DDE06_RS05850	COG1643	Atp-dependent helicase
DDE06_RS05860	COG2072	flavoprotein involved in K transport
DDE06_RS05880	COG1175	transmembrane transport
DDE06_RS05885	COG0395	ABC-type sugar transport system, permease component
DDE06_RS05905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDE06_RS05915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DDE06_RS05920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DDE06_RS05925	COG1780	Probably involved in ribonucleotide reductase function
DDE06_RS05940	COG1854	S-ribosylhomocysteine lyase activity
DDE06_RS05945	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DDE06_RS05975	COG1716	ATPase activity
DDE06_RS05975	COG1131	(ABC) transporter
DDE06_RS05975	COG0842	Transport permease protein
DDE06_RS06005	COG3764	Sortase (surface protein transpeptidase)
DDE06_RS06015	COG0705	Rhomboid family
DDE06_RS06055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DDE06_RS06060	COG0187	DNA topoisomerase II activity
DDE06_RS06070	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DDE06_RS06075	COG0592	DNA-directed DNA polymerase activity
DDE06_RS06080	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DDE06_RS06085	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DDE06_RS06090	COG0594	ribonuclease P activity
DDE06_RS06095	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DDE06_RS06100	COG0706	membrane insertase activity
DDE06_RS06110	COG0357	Ribosomal RNA small subunit methyltransferase G
DDE06_RS06115	COG1192	Involved in chromosome partitioning
DDE06_RS06125	COG1181	Belongs to the D-alanine--D-alanine ligase family
DDE06_RS06130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDE06_RS06135	COG0492	ferredoxin-NADP+ reductase activity
DDE06_RS06155	COG0617	tRNA 3'-terminal CCA addition
DDE06_RS06165	COG0628	permease
DDE06_RS06170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DDE06_RS06175	COG0360	Binds together with S18 to 16S ribosomal RNA
DDE06_RS06185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DDE06_RS06190	COG0359	binds to the 23S rRNA
DDE06_RS06195	COG0737	Belongs to the 5'-nucleotidase family
DDE06_RS06210	COG0305	Participates in initiation and elongation during chromosome replication
DDE06_RS06215	COG2814	Major facilitator Superfamily
DDE06_RS06225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DDE06_RS06240	COG0351	phosphomethylpyrimidine kinase
DDE06_RS06285	COG1428	Deoxynucleoside kinase
DDE06_RS06295	COG0343	queuine tRNA-ribosyltransferase activity
DDE06_RS06300	COG2205	protein histidine kinase activity
DDE06_RS06305	COG0745	RESPONSE REGULATOR receiver
DDE06_RS06320	COG1136	(ABC) transporter
DDE06_RS06325	COG0577	efflux transmembrane transporter activity
DDE06_RS06355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DDE06_RS06370	COG1643	Atp-dependent helicase
DDE06_RS06415	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DDE06_RS06420	COG1252	NADH dehydrogenase
DDE06_RS06460	COG1070	Carbohydrate kinase
DDE06_RS06470	COG1879	ABC-type sugar transport system periplasmic component
DDE06_RS06480	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDE06_RS06485	COG1129	ABC transporter
DDE06_RS06515	COG0471	metal ion transport
DDE06_RS06530	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DDE06_RS06535	COG1129	ABC transporter
DDE06_RS06540	COG2375	cellular response to nickel ion
DDE06_RS06540	COG1132	(ABC) transporter
DDE06_RS06545	COG1132	(ABC) transporter
DDE06_RS06585	COG1175	transmembrane transport
DDE06_RS06595	COG1846	Transcriptional regulator
DDE06_RS06595	COG1940	carbohydrate kinase activity
DDE06_RS06600	COG1940	carbohydrate kinase activity
DDE06_RS06610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDE06_RS06615	COG0601	transmembrane transport
DDE06_RS06625	COG1940	carbohydrate kinase activity
DDE06_RS06640	COG3142	Participates in the control of copper homeostasis
DDE06_RS06655	COG1904	glucuronate isomerase
DDE06_RS06660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DDE06_RS06665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
DDE06_RS06665	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
DDE06_RS06675	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DDE06_RS06680	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DDE06_RS06685	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDE06_RS06690	COG4605	iron ion homeostasis
DDE06_RS06695	COG4604	ABC transporter, ATP-binding protein
DDE06_RS06705	COG3962	Belongs to the TPP enzyme family
DDE06_RS06710	COG3718	enzyme involved in inositol metabolism
DDE06_RS06730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DDE06_RS06735	COG0673	inositol 2-dehydrogenase activity
DDE06_RS06745	COG0673	inositol 2-dehydrogenase activity
DDE06_RS06755	COG1172	Belongs to the binding-protein-dependent transport system permease family
DDE06_RS06760	COG1879	ABC-type sugar transport system periplasmic component
DDE06_RS06765	COG0483	inositol monophosphate 1-phosphatase activity
DDE06_RS06770	COG2271	Major facilitator Superfamily
DDE06_RS06775	COG1609	Transcriptional regulator
DDE06_RS06780	COG1063	alcohol dehydrogenase
DDE06_RS06800	COG1129	ABC transporter
DDE06_RS06805	COG1132	(ABC) transporter
DDE06_RS06815	COG1309	transcriptional regulator
DDE06_RS06850	COG0586	Pfam SNARE associated Golgi protein
DDE06_RS06855	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DDE06_RS06860	COG1950	PFAM Membrane protein of
DDE06_RS06865	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DDE06_RS06890	COG0667	Aldo Keto reductase
DDE06_RS06895	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DDE06_RS06925	COG1175	transmembrane transport
DDE06_RS06930	COG0395	ABC-type sugar transport system, permease component
DDE06_RS06940	COG3345	alpha-galactosidase
DDE06_RS06960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDE06_RS06965	COG1120	ATPase activity
DDE06_RS07010	COG0588	phosphoglycerate mutase activity
DDE06_RS07025	COG5002	protein histidine kinase activity
DDE06_RS07040	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DDE06_RS07045	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DDE06_RS07065	COG3775	system Galactitol-specific IIC component
DDE06_RS07080	COG2376	Dihydroxyacetone kinase
DDE06_RS07105	COG1136	(ABC) transporter
DDE06_RS07115	COG0215	cysteine-tRNA ligase activity
DDE06_RS07120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DDE06_RS07135	COG2233	PERMEase
DDE06_RS07160	COG1966	Carbon starvation protein
DDE06_RS07175	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DDE06_RS07205	COG1175	transmembrane transport
DDE06_RS07210	COG1653	transport
DDE06_RS07220	COG0673	inositol 2-dehydrogenase activity
DDE06_RS07230	COG3842	ATPase activity
DDE06_RS07255	COG1131	(ABC) transporter
DDE06_RS07280	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DDE06_RS07295	COG0459	protein refolding
DDE06_RS07310	COG4221	oxidoreductase activity
DDE06_RS07320	COG2205	protein histidine kinase activity
DDE06_RS07325	COG0745	RESPONSE REGULATOR receiver
DDE06_RS07335	COG1842	Phage shock protein A
DDE06_RS07345	COG1278	Cold shock
DDE06_RS07360	COG2252	PERMEase
DDE06_RS07365	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DDE06_RS07380	COG0791	NLP P60 protein
DDE06_RS07380	COG1388	LysM domain
DDE06_RS07445	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DDE06_RS07450	COG3657	addiction module killer protein
DDE06_RS07465	COG0596	Alpha beta hydrolase
DDE06_RS07480	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DDE06_RS07485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDE06_RS07490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DDE06_RS07495	COG1120	ATPase activity
DDE06_RS07500	COG2188	Transcriptional regulator
DDE06_RS07505	COG0657	acetylesterase activity
DDE06_RS07510	COG0477	Major facilitator Superfamily
DDE06_RS07525	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DDE06_RS07530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDE06_RS07535	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DDE06_RS07540	COG0254	rRNA binding
DDE06_RS07545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DDE06_RS07560	COG3830	Belongs to the UPF0237 family
DDE06_RS07565	COG2848	UPF0210 protein
DDE06_RS07575	COG1511	domain protein
DDE06_RS07590	COG3711	transcriptional antiterminator
DDE06_RS07600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DDE06_RS07610	COG1051	belongs to the nudix hydrolase family
DDE06_RS07630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DDE06_RS07630	COG1263	PTS System
DDE06_RS07635	COG2190	(PTS) system
DDE06_RS07640	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DDE06_RS07660	COG1556	Lactate utilization protein
DDE06_RS07670	COG0247	lactate metabolic process
DDE06_RS07675	COG1620	l-lactate permease
DDE06_RS07700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DDE06_RS07705	COG2813	Specifically methylates the guanine in position
DDE06_RS07720	COG1131	(ABC) transporter
DDE06_RS07740	COG2873	o-acetylhomoserine
DDE06_RS07760	COG1335	isochorismatase
DDE06_RS07795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DDE06_RS07800	COG0084	hydrolase, TatD family'
DDE06_RS07810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DDE06_RS07815	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DDE06_RS07820	COG0488	(ABC) transporter
DDE06_RS07830	COG1668	transmembrane transport
DDE06_RS07835	COG4152	abc transporter atp-binding protein
DDE06_RS07850	COG1309	transcriptional regulator
DDE06_RS07860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DDE06_RS07870	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DDE06_RS07875	COG0193	aminoacyl-tRNA hydrolase activity
DDE06_RS07890	COG0148	phosphopyruvate hydratase activity
DDE06_RS07935	COG1725	Transcriptional regulator
DDE06_RS07940	COG1131	(ABC) transporter
DDE06_RS07955	COG1012	belongs to the aldehyde dehydrogenase family
DDE06_RS07960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DDE06_RS07975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DDE06_RS07980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DDE06_RS07985	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DDE06_RS07995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DDE06_RS08000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DDE06_RS08005	COG1722	exodeoxyribonuclease VII activity
DDE06_RS08015	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DDE06_RS08030	COG4555	ABC transporter
DDE06_RS08045	COG1162	GTPase activity
DDE06_RS08050	COG1322	Protein conserved in bacteria
DDE06_RS08055	COG0012	GTP binding
DDE06_RS08085	COG0477	Major facilitator Superfamily
DDE06_RS08100	COG0366	Alpha amylase catalytic
DDE06_RS08115	COG0395	ABC-type sugar transport system, permease component
DDE06_RS08135	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DDE06_RS08140	COG0549	Belongs to the carbamate kinase family
DDE06_RS08145	COG1834	amidinotransferase
DDE06_RS08155	COG0477	Major facilitator Superfamily
DDE06_RS08160	COG3226	Transcriptional regulator
DDE06_RS08165	COG0431	NADPH-dependent FMN reductase
DDE06_RS08175	COG1780	Probably involved in ribonucleotide reductase function
DDE06_RS08200	COG1970	mechanosensitive ion channel activity
DDE06_RS08205	COG0242	peptide deformylase activity
DDE06_RS08215	COG2116	formate transmembrane transporter activity
DDE06_RS08230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DDE06_RS08235	COG0444	Belongs to the ABC transporter superfamily
DDE06_RS08240	COG4608	Belongs to the ABC transporter superfamily
DDE06_RS08265	COG1840	ABC-type Fe3 transport system, periplasmic component
DDE06_RS08270	COG3842	ATPase activity
DDE06_RS08275	COG1178	ABC-type Fe3 transport system permease component
DDE06_RS08300	COG1846	Transcriptional regulator
DDE06_RS08300	COG1940	carbohydrate kinase activity
DDE06_RS08305	COG1175	transmembrane transport
DDE06_RS08310	COG0395	ABC-type sugar transport system, permease component
DDE06_RS08320	COG1501	Belongs to the glycosyl hydrolase 31 family
DDE06_RS08325	COG0366	Alpha amylase catalytic
DDE06_RS08330	COG0425	Belongs to the sulfur carrier protein TusA family
DDE06_RS08335	COG2391	methyltransferase activity
DDE06_RS08340	COG2838	Isocitrate dehydrogenase
DDE06_RS08355	COG1362	aminopeptidase activity
DDE06_RS08365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DDE06_RS08370	COG0321	lipoyl(octanoyl) transferase activity
DDE06_RS08400	COG1132	(ABC) transporter
DDE06_RS08410	COG1217	gtp-binding protein TYPA
DDE06_RS08445	COG0424	maF-like protein
DDE06_RS08460	COG0745	RESPONSE REGULATOR receiver
DDE06_RS08465	COG0642	Histidine kinase
DDE06_RS08475	COG1316	TRANSCRIPTIONal
DDE06_RS08480	COG1316	TRANSCRIPTIONal
DDE06_RS08495	COG1088	dTDP-glucose 4,6-dehydratase activity
DDE06_RS08520	COG0673	inositol 2-dehydrogenase activity
DDE06_RS08615	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DDE06_RS08630	COG0483	inositol monophosphate 1-phosphatase activity
DDE06_RS08675	COG0714	Associated with various cellular activities
DDE06_RS08695	COG0745	RESPONSE REGULATOR receiver
DDE06_RS08700	COG5000	phosphorelay sensor kinase activity
DDE06_RS08700	COG5002	protein histidine kinase activity
DDE06_RS08705	COG5401	PFAM Sporulation and spore germination
DDE06_RS08710	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DDE06_RS08715	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DDE06_RS08725	COG1666	GTP binding
DDE06_RS08745	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DDE06_RS08760	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DDE06_RS08775	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DDE06_RS08785	COG0436	Aminotransferase
DDE06_RS08800	COG0250	Participates in transcription elongation, termination and antitermination
DDE06_RS08805	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DDE06_RS08810	COG0081	regulation of translation
DDE06_RS08820	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DDE06_RS08825	COG0222	ribosome binding
DDE06_RS08830	COG0085	RNA polymerase activity
DDE06_RS08835	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DDE06_RS08840	COG0833	amino acid
DDE06_RS08845	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DDE06_RS08850	COG0049	tRNA binding
DDE06_RS08855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DDE06_RS08860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DDE06_RS08870	COG0546	phosphoglycolate phosphatase activity
DDE06_RS08875	COG0051	transcription antitermination factor activity, RNA binding
DDE06_RS08880	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DDE06_RS08885	COG0088	Forms part of the polypeptide exit tunnel
DDE06_RS08890	COG0089	rRNA binding
DDE06_RS08895	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DDE06_RS08900	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DDE06_RS08905	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DDE06_RS08910	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DDE06_RS08915	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DDE06_RS08930	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DDE06_RS08935	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DDE06_RS08940	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DDE06_RS08945	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DDE06_RS08950	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DDE06_RS08955	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DDE06_RS08965	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DDE06_RS08970	COG1841	ribosomal large subunit assembly
DDE06_RS08975	COG0200	Binds to the 23S rRNA
DDE06_RS08985	COG0563	adenylate kinase activity
DDE06_RS08995	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DDE06_RS09000	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DDE06_RS09005	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DDE06_RS09015	COG0202	RNA polymerase activity
DDE06_RS09020	COG0203	ribosomal protein L17
DDE06_RS09025	COG1666	GTP binding
DDE06_RS09035	COG0789	Transcriptional regulator
DDE06_RS09040	COG4598	ABC transporter
DDE06_RS09045	COG0765	amino acid transport
DDE06_RS09055	COG1940	carbohydrate kinase activity
DDE06_RS09060	COG0101	tRNA pseudouridine synthase activity
DDE06_RS09080	COG1122	ATPase activity
DDE06_RS09085	COG4720	Psort location CytoplasmicMembrane, score
DDE06_RS09095	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DDE06_RS09100	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DDE06_RS09110	COG1072	(Pantothenic acid kinase))
DDE06_RS09115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DDE06_RS09125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DDE06_RS09130	COG0802	atpase or kinase
DDE06_RS09155	COG1053	succinate dehydrogenase
DDE06_RS09160	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DDE06_RS09170	COG0733	neurotransmitter:sodium symporter activity
DDE06_RS09175	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DDE06_RS09180	COG0428	transporter
DDE06_RS09195	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DDE06_RS09205	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DDE06_RS09210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DDE06_RS09215	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DDE06_RS09220	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DDE06_RS09225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DDE06_RS09230	COG0151	Belongs to the GarS family
DDE06_RS09235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DDE06_RS09260	COG0516	GMP reductase activity
DDE06_RS09265	COG0114	fumarate hydratase activity
DDE06_RS09275	COG1136	(ABC) transporter
DDE06_RS09290	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DDE06_RS09295	COG0280	phosphate acetyltransferase
DDE06_RS09295	COG0857	belongs to the CobB CobQ family
DDE06_RS09320	COG4974	Belongs to the 'phage' integrase family
DDE06_RS09355	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DDE06_RS09385	COG1401	restriction endodeoxyribonuclease activity
DDE06_RS09430	COG0791	NLP P60 protein
DDE06_RS09450	COG3505	Type IV secretory pathway VirD4
DDE06_RS09465	COG1484	DNA-dependent DNA replication
DDE06_RS09490	COG0095	Lipoate-protein ligase
DDE06_RS09545	COG2755	lipolytic protein G-D-S-L family
DDE06_RS09545	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DDE06_RS09550	COG0045	succinate-CoA ligase (ADP-forming) activity
DDE06_RS09580	COG0205	6-phosphofructokinase activity
DDE06_RS09585	COG0166	Belongs to the GPI family
DDE06_RS09630	COG2826	transposase and inactivated derivatives, IS30 family
DDE06_RS09635	COG2826	transposase and inactivated derivatives, IS30 family
DDE06_RS09650	COG0039	L-malate dehydrogenase activity
DDE06_RS09690	COG2030	dehydratase
DDE06_RS09695	COG2271	Major facilitator Superfamily
DDE06_RS09700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DDE06_RS09715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DDE06_RS09720	COG0644	oxidoreductase
DDE06_RS09740	COG4770	biotin carboxylase activity
DDE06_RS09745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DDE06_RS09750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DDE06_RS09760	COG1268	BioY protein
DDE06_RS09770	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DDE06_RS09775	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DDE06_RS09790	COG0662	Cupin 2, conserved barrel domain protein
DDE06_RS09790	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DDE06_RS09795	COG1744	ABC transporter substrate-binding protein PnrA-like
DDE06_RS09800	COG3845	ABC transporter
DDE06_RS09805	COG4603	Belongs to the binding-protein-dependent transport system permease family
DDE06_RS09810	COG1079	Belongs to the binding-protein-dependent transport system permease family
DDE06_RS09830	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DDE06_RS09835	COG2814	Major facilitator Superfamily
DDE06_RS09840	COG1309	transcriptional regulator
DDE06_RS09845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DDE06_RS09855	COG1611	Belongs to the LOG family
DDE06_RS09880	COG2239	Acts as a magnesium transporter
DDE06_RS09885	COG0006	proline dipeptidase activity
DDE06_RS09895	COG2095	MarC family integral membrane protein
DDE06_RS09900	COG0513	Belongs to the DEAD box helicase family
DDE06_RS09960	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DDE06_RS09965	COG2884	Cell division ATP-binding protein ftsE
DDE06_RS09970	COG2177	Part of the ABC transporter FtsEX involved in
DDE06_RS09975	COG0739	heme binding
DDE06_RS09990	COG1619	proteins homologs of microcin C7 resistance protein MccF
DDE06_RS10020	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DDE06_RS10025	COG1846	Transcriptional regulator
DDE06_RS10040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DDE06_RS10065	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DDE06_RS10080	COG2985	domain, Protein
DDE06_RS10080	COG0569	domain protein
DDE06_RS10105	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DDE06_RS10115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DDE06_RS10125	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DDE06_RS10130	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DDE06_RS10155	COG1022	Amp-dependent synthetase and ligase
DDE06_RS10160	COG0179	Fumarylacetoacetate (FAA) hydrolase
DDE06_RS10215	COG0339	signal peptide processing
DDE06_RS10225	COG4975	Glucose uptake
DDE06_RS10235	COG0438	transferase activity, transferring glycosyl groups
DDE06_RS10255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DDE06_RS10260	COG1181	Belongs to the D-alanine--D-alanine ligase family
DDE06_RS10270	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DDE06_RS10280	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DDE06_RS10295	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DDE06_RS10310	COG0571	ribonuclease III activity
DDE06_RS10315	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DDE06_RS10335	COG1132	(ABC) transporter
DDE06_RS10340	COG1132	(ABC) transporter
DDE06_RS10350	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DDE06_RS10355	COG4988	ABC transporter
DDE06_RS10360	COG1294	oxidase, subunit
DDE06_RS10365	COG1271	oxidase subunit
DDE06_RS10375	COG1530	ribonuclease E activity
DDE06_RS10380	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DDE06_RS10390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DDE06_RS10400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DDE06_RS10405	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DDE06_RS10415	COG0799	negative regulation of ribosome biogenesis
DDE06_RS10420	COG0406	alpha-ribazole phosphatase activity
DDE06_RS10455	COG0235	Class ii aldolase
DDE06_RS10460	COG0738	Major facilitator superfamily
DDE06_RS10470	COG1609	Transcriptional regulator
DDE06_RS10475	COG0133	tryptophan synthase activity
DDE06_RS10480	COG0726	polysaccharide deacetylase
DDE06_RS10525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DDE06_RS10540	COG0826	peptidase U32
DDE06_RS10545	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DDE06_RS10555	COG1113	amino acid transport
DDE06_RS10560	COG1464	Belongs to the NlpA lipoprotein family
DDE06_RS10565	COG2011	ABC-type metal ion transport system permease component
DDE06_RS10575	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DDE06_RS10575	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DDE06_RS10580	COG1113	amino acid transport
DDE06_RS10590	COG1395	domain, Protein
DDE06_RS10600	COG0671	phosphoesterase, PA-phosphatase related
DDE06_RS10615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DDE06_RS10620	COG1121	(ABC) transporter
DDE06_RS10630	COG0803	Belongs to the bacterial solute-binding protein 9 family
DDE06_RS10650	COG1435	thymidine kinase activity
DDE06_RS10660	COG0813	purine-nucleoside phosphorylase activity
DDE06_RS10685	COG0495	leucyl-tRNA aminoacylation
DDE06_RS10700	COG0433	COG0433 Predicted ATPase
DDE06_RS10720	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DDE06_RS10725	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DDE06_RS10730	COG0268	Binds directly to 16S ribosomal RNA
DDE06_RS10755	COG0481	GTPase activity
DDE06_RS10760	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DDE06_RS10780	COG1420	regulation of RNA biosynthetic process
DDE06_RS10785	COG0484	heat shock protein binding
DDE06_RS10790	COG1385	rRNA (uridine-N3-)-methyltransferase activity