locus-tag	class	description
EB776_RS00105	COG3617	BRO family, N-terminal domain
EB776_RS00170	COG2189	Belongs to the N(4) N(6)-methyltransferase family
EB776_RS00180	COG1002	Type II restriction enzyme, methylase subunits
EB776_RS00185	COG1061	Type III restriction enzyme res subunit
EB776_RS00190	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EB776_RS00245	COG1518	maintenance of DNA repeat elements
EB776_RS00260	COG3609	addiction module antidote protein, CC2985 family
EB776_RS00275	COG0366	Alpha amylase catalytic
EB776_RS00280	COG0395	ABC-type sugar transport system, permease component
EB776_RS00285	COG1175	transmembrane transport
EB776_RS00300	COG0574	Belongs to the PEP-utilizing enzyme family
EB776_RS00300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EB776_RS00305	COG0277	FAD linked oxidase domain protein
EB776_RS00305	COG0247	lactate metabolic process
EB776_RS00315	COG2267	carboxylic ester hydrolase activity
EB776_RS00320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EB776_RS00325	COG0791	NLP P60 protein
EB776_RS00330	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EB776_RS00345	COG0037	tRNA processing
EB776_RS00355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EB776_RS00360	COG0302	gtp cyclohydrolase
EB776_RS00390	COG1609	Transcriptional regulator
EB776_RS00410	COG3250	beta-galactosidase activity
EB776_RS00420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB776_RS00420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EB776_RS00425	COG1461	Dihydroxyacetone kinase
EB776_RS00430	COG2376	Dihydroxyacetone kinase
EB776_RS00440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EB776_RS00445	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EB776_RS00455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EB776_RS00460	COG2409	Drug exporters of the RND superfamily
EB776_RS00465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EB776_RS00470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EB776_RS00480	COG3386	PFAM SMP-30 Gluconolaconase
EB776_RS00485	COG0247	lactate metabolic process
EB776_RS00490	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EB776_RS00495	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EB776_RS00510	COG1194	a g-specific adenine glycosylase
EB776_RS00520	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EB776_RS00525	COG0569	domain protein
EB776_RS00530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EB776_RS00545	COG1846	Transcriptional regulator
EB776_RS00550	COG0406	alpha-ribazole phosphatase activity
EB776_RS00575	COG0395	ABC-type sugar transport system, permease component
EB776_RS00580	COG1175	transmembrane transport
EB776_RS00590	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EB776_RS00595	COG4948	Mandelate Racemase Muconate Lactonizing
EB776_RS00600	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EB776_RS00605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB776_RS00610	COG1169	isochorismate synthase
EB776_RS00615	COG2226	methyltransferase
EB776_RS00620	COG0644	oxidoreductase
EB776_RS00630	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB776_RS00635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB776_RS00640	COG0649	NAD binding
EB776_RS00650	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EB776_RS00655	COG1034	ATP synthesis coupled electron transport
EB776_RS00660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EB776_RS00665	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EB776_RS00670	COG0839	Belongs to the complex I subunit 6 family
EB776_RS00675	COG0713	ATP synthesis coupled electron transport
EB776_RS00680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EB776_RS00690	COG1007	ATP synthesis coupled electron transport
EB776_RS00695	COG0142	geranyltranstransferase activity
EB776_RS00700	COG0653	protein targeting
EB776_RS00740	COG0419	ATPase involved in DNA repair
EB776_RS00745	COG0420	3'-5' exonuclease activity
EB776_RS00750	COG0483	inositol monophosphate 1-phosphatase activity
EB776_RS00755	COG1162	GTPase activity
EB776_RS00760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EB776_RS00780	COG0657	acetylesterase activity
EB776_RS00795	COG0601	transmembrane transport
EB776_RS00800	COG0444	Belongs to the ABC transporter superfamily
EB776_RS00805	COG4608	Belongs to the ABC transporter superfamily
EB776_RS00810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB776_RS00820	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EB776_RS00825	COG0363	glucosamine-6-phosphate deaminase activity
EB776_RS00835	COG1595	DNA-templated transcription, initiation
EB776_RS00860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EB776_RS00880	COG3103	Sh3 type 3 domain protein
EB776_RS00880	COG0791	NLP P60 protein
EB776_RS00880	COG1388	LysM domain
EB776_RS00890	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB776_RS00890	COG0567	Dehydrogenase, E1 component
EB776_RS00895	COG1253	flavin adenine dinucleotide binding
EB776_RS00905	COG0739	heme binding
EB776_RS00910	COG0584	glycerophosphoryl diester phosphodiesterase
EB776_RS00950	COG0018	arginyl-trna synthetase
EB776_RS00960	COG0460	homoserine dehydrogenase
EB776_RS00965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EB776_RS00970	COG0083	homoserine kinase activity
EB776_RS00985	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EB776_RS01010	COG0356	it plays a direct role in the translocation of protons across the membrane
EB776_RS01015	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EB776_RS01020	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EB776_RS01025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EB776_RS01030	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EB776_RS01035	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EB776_RS01040	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EB776_RS01045	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EB776_RS01055	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EB776_RS01100	COG1609	Transcriptional regulator
EB776_RS01110	COG1175	transmembrane transport
EB776_RS01115	COG3833	ABC-type maltose transport systems, permease component
EB776_RS01125	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EB776_RS01130	COG3281	Trehalose synthase
EB776_RS01135	COG0366	Alpha amylase catalytic
EB776_RS01140	COG0366	Alpha amylase catalytic
EB776_RS01170	COG0058	SHG alpha-glucan phosphorylase activity
EB776_RS01175	COG0180	Tryptophanyl-tRNA synthetase
EB776_RS01205	COG3480	Lon protease (S16) C-terminal proteolytic domain
EB776_RS01215	COG1615	UPF0182 protein
EB776_RS01220	COG0366	Alpha amylase catalytic
EB776_RS01220	COG1470	cell adhesion involved in biofilm formation
EB776_RS01240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB776_RS01245	COG1131	(ABC) transporter
EB776_RS01255	COG0387	Pfam Sodium calcium exchanger
EB776_RS01265	COG1053	succinate dehydrogenase
EB776_RS01290	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EB776_RS01325	COG4585	Histidine kinase
EB776_RS01330	COG2135	peptidase activity
EB776_RS01335	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EB776_RS01345	COG1397	ADP-ribosylglycohydrolase
EB776_RS01355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB776_RS01370	COG1404	Belongs to the peptidase S8 family
EB776_RS01375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EB776_RS01380	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EB776_RS01385	COG0154	amidase activity
EB776_RS01390	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EB776_RS01445	COG0129	dihydroxy-acid dehydratase activity
EB776_RS01450	COG2985	domain, Protein
EB776_RS01450	COG0569	domain protein
EB776_RS01460	COG0440	acetolactate synthase activity
EB776_RS01465	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EB776_RS01485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB776_RS01490	COG1882	Formate acetyltransferase
EB776_RS01520	COG0438	transferase activity, transferring glycosyl groups
EB776_RS01525	COG4750	Nucleotidyl transferase
EB776_RS01530	COG3475	LICD family
EB776_RS01535	COG1442	glycosyl transferase family 8
EB776_RS01535	COG1216	Glycosyl transferase, family 2
EB776_RS01565	COG0463	Glycosyl transferase, family 2
EB776_RS01595	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EB776_RS01625	COG1946	Acyl-CoA thioesterase
EB776_RS01640	COG0519	Catalyzes the synthesis of GMP from XMP
EB776_RS01650	COG2354	Protein conserved in bacteria
EB776_RS01655	COG3590	peptidase
EB776_RS01665	COG1045	serine acetyltransferase
EB776_RS01675	COG1739	Uncharacterized protein family UPF0029
EB776_RS01690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB776_RS01740	COG0488	(ABC) transporter
EB776_RS01755	COG1609	Transcriptional regulator
EB776_RS01760	COG3250	beta-galactosidase activity
EB776_RS01780	COG0667	Aldo Keto reductase
EB776_RS01785	COG0544	peptidyl-prolyl cis-trans isomerase activity
EB776_RS01790	COG0740	serine-type endopeptidase activity
EB776_RS01795	COG0740	serine-type endopeptidase activity
EB776_RS01800	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EB776_RS01805	COG0287	Prephenate dehydrogenase
EB776_RS01805	COG1605	Chorismate mutase
EB776_RS01825	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EB776_RS01840	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EB776_RS01845	COG0285	dihydrofolate synthase activity
EB776_RS01850	COG0105	UTP biosynthetic process
EB776_RS01890	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EB776_RS01895	COG0228	four-way junction DNA binding
EB776_RS01900	COG1837	Belongs to the UPF0109 family
EB776_RS01905	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EB776_RS01915	COG0335	large ribosomal subunit rRNA binding
EB776_RS01920	COG0681	Belongs to the peptidase S26 family
EB776_RS01925	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EB776_RS01950	COG4974	Belongs to the 'phage' integrase family
EB776_RS01955	COG4942	peptidase
EB776_RS01955	COG1388	LysM domain
EB776_RS01960	COG2860	membrane
EB776_RS01965	COG0052	Belongs to the universal ribosomal protein uS2 family
EB776_RS01970	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EB776_RS01980	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EB776_RS01985	COG0644	oxidoreductase
EB776_RS02010	COG0233	cytoplasmic translational termination
EB776_RS02020	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EB776_RS02030	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EB776_RS02035	COG0750	zinc metalloprotease
EB776_RS02040	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EB776_RS02050	COG0442	prolyl-tRNA aminoacylation
EB776_RS02060	COG0779	Required for maturation of 30S ribosomal subunits
EB776_RS02075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EB776_RS02080	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EB776_RS02085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EB776_RS02090	COG3852	Histidine kinase
EB776_RS02095	COG0745	RESPONSE REGULATOR receiver
EB776_RS02100	COG2271	Major facilitator Superfamily
EB776_RS02110	COG3842	ATPase activity
EB776_RS02140	COG1129	ABC transporter
EB776_RS02140	COG0842	Transport permease protein
EB776_RS02155	COG1185	polyribonucleotide nucleotidyltransferase activity
EB776_RS02165	COG0612	Peptidase, M16
EB776_RS02170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EB776_RS02175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EB776_RS02190	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EB776_RS02195	COG1674	ftsk spoiiie
EB776_RS02210	COG1546	Belongs to the CinA family
EB776_RS02210	COG1058	Belongs to the CinA family
EB776_RS02215	COG1396	sequence-specific DNA binding
EB776_RS02225	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EB776_RS02230	COG2137	regulation of response to DNA damage stimulus
EB776_RS02235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EB776_RS02240	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EB776_RS02250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EB776_RS02260	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EB776_RS02270	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EB776_RS02275	COG0318	PFAM AMP-dependent synthetase and ligase
EB776_RS02280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EB776_RS02300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EB776_RS02310	COG2001	Belongs to the MraZ family
EB776_RS02315	COG0275	rRNA processing
EB776_RS02325	COG0768	penicillin binding
EB776_RS02330	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EB776_RS02335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EB776_RS02340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EB776_RS02345	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EB776_RS02355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EB776_RS02360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EB776_RS02370	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EB776_RS02380	COG1799	cell septum assembly
EB776_RS02395	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EB776_RS02410	COG0587	DNA-directed DNA polymerase activity
EB776_RS02425	COG0735	belongs to the Fur family
EB776_RS02430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EB776_RS02435	COG1121	(ABC) transporter
EB776_RS02445	COG0423	glycine-tRNA ligase activity
EB776_RS02470	COG0358	DNA primase activity
EB776_RS02480	COG0805	protein transport
EB776_RS02485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EB776_RS02520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB776_RS02525	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EB776_RS02560	COG1090	epimerase
EB776_RS02580	COG0009	L-threonylcarbamoyladenylate synthase
EB776_RS02600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EB776_RS02625	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EB776_RS02630	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EB776_RS02635	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EB776_RS02645	COG3022	response to hydroperoxide
EB776_RS02655	COG1940	carbohydrate kinase activity
EB776_RS02670	COG0174	glutamine synthetase
EB776_RS02675	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EB776_RS02685	COG0174	glutamine synthetase
EB776_RS02705	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB776_RS02710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB776_RS02720	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EB776_RS02735	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB776_RS02775	COG0205	6-phosphofructokinase activity
EB776_RS02780	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EB776_RS02785	COG0515	serine threonine protein kinase
EB776_RS02785	COG2815	serine threonine protein kinase
EB776_RS02800	COG0142	geranyltranstransferase activity
EB776_RS02815	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EB776_RS02820	COG1199	ATP-dependent helicase activity
EB776_RS02820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EB776_RS02830	COG0187	DNA topoisomerase II activity
EB776_RS02845	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EB776_RS02885	COG0569	domain protein
EB776_RS02900	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EB776_RS02910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EB776_RS02975	COG2197	response regulator
EB776_RS02980	COG1760	l-serine dehydratase
EB776_RS02985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EB776_RS02990	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EB776_RS03000	COG0438	transferase activity, transferring glycosyl groups
EB776_RS03010	COG1051	belongs to the nudix hydrolase family
EB776_RS03015	COG0217	transcriptional regulatory protein
EB776_RS03020	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EB776_RS03025	COG0632	four-way junction helicase activity
EB776_RS03030	COG2255	four-way junction helicase activity
EB776_RS03040	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EB776_RS03045	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EB776_RS03050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EB776_RS03055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EB776_RS03065	COG1196	nuclear chromosome segregation
EB776_RS03070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB776_RS03075	COG0124	histidyl-tRNA synthetase
EB776_RS03080	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EB776_RS03085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EB776_RS03105	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EB776_RS03120	COG2409	Drug exporters of the RND superfamily
EB776_RS03130	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EB776_RS03140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EB776_RS03145	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EB776_RS03165	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EB776_RS03175	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EB776_RS03180	COG2217	Heavy metal translocating P-type atpase
EB776_RS03185	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EB776_RS03190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EB776_RS03195	COG0505	Belongs to the CarA family
EB776_RS03200	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EB776_RS03210	COG0194	GDP metabolic process
EB776_RS03215	COG1758	RNA polymerase activity
EB776_RS03225	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EB776_RS03230	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EB776_RS03235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EB776_RS03245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EB776_RS03250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EB776_RS03255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB776_RS03260	COG0140	phosphoribosyl-ATP diphosphatase activity
EB776_RS03265	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EB776_RS03295	COG4581	dead DEAH box helicase
EB776_RS03305	COG1216	Glycosyl transferase, family 2
EB776_RS03345	COG0205	6-phosphofructokinase activity
EB776_RS03350	COG1160	GTP binding
EB776_RS03355	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EB776_RS03365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EB776_RS03390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EB776_RS03405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EB776_RS03410	COG0149	triose-phosphate isomerase activity
EB776_RS03415	COG0126	phosphoglycerate kinase activity
EB776_RS03420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EB776_RS03425	COG1481	regulation of sporulation
EB776_RS03440	COG0322	excinuclease ABC activity
EB776_RS03445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EB776_RS03465	COG0556	nucleotide-excision repair
EB776_RS03470	COG0237	dephospho-CoA kinase activity
EB776_RS03475	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EB776_RS03480	COG1136	(ABC) transporter
EB776_RS03515	COG0469	pyruvate kinase activity
EB776_RS03520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EB776_RS03525	COG0134	indole-3-glycerol-phosphate synthase activity
EB776_RS03535	COG0107	imidazoleglycerol-phosphate synthase activity
EB776_RS03550	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EB776_RS03560	COG4122	O-methyltransferase activity
EB776_RS03565	COG1222	aaa ATPase
EB776_RS03585	COG1968	undecaprenyl-diphosphatase activity
EB776_RS03600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB776_RS03610	COG0519	Catalyzes the synthesis of GMP from XMP
EB776_RS03610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EB776_RS03615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EB776_RS03635	COG0587	DNA-directed DNA polymerase activity
EB776_RS03650	COG1881	PFAM PEBP family protein
EB776_RS03685	COG1119	ATPase activity
EB776_RS03690	COG0297	glycogen (starch) synthase activity
EB776_RS03700	COG0577	efflux transmembrane transporter activity
EB776_RS03700	COG1136	(ABC) transporter
EB776_RS03705	COG3830	Belongs to the UPF0237 family
EB776_RS03705	COG0560	Phosphoserine phosphatase
EB776_RS03715	COG0488	(ABC) transporter
EB776_RS03720	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EB776_RS03725	COG2151	metal-sulfur cluster biosynthetic enzyme
EB776_RS03740	COG0396	ATPase activity
EB776_RS03770	COG0728	peptidoglycan biosynthetic process
EB776_RS03790	COG0497	DNA recombination
EB776_RS03795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EB776_RS03805	COG0647	UMP catabolic process
EB776_RS03835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EB776_RS03840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EB776_RS03845	COG1121	(ABC) transporter
EB776_RS03850	COG0803	Belongs to the bacterial solute-binding protein 9 family
EB776_RS03855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EB776_RS03870	COG1476	TRANSCRIPTIONal
EB776_RS03880	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EB776_RS03885	COG1438	arginine binding
EB776_RS03900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EB776_RS03905	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EB776_RS03915	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EB776_RS03920	COG1902	pentaerythritol trinitrate reductase activity
EB776_RS03925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB776_RS03940	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EB776_RS03945	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EB776_RS03955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EB776_RS03960	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EB776_RS03970	COG0131	Imidazoleglycerol-phosphate dehydratase
EB776_RS03980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EB776_RS03985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EB776_RS03990	COG1381	Involved in DNA repair and RecF pathway recombination
EB776_RS03995	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EB776_RS04030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EB776_RS04040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EB776_RS04045	COG0484	heat shock protein binding
EB776_RS04050	COG1420	regulation of RNA biosynthetic process
EB776_RS04070	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EB776_RS04075	COG0481	GTPase activity
EB776_RS04100	COG0268	Binds directly to 16S ribosomal RNA
EB776_RS04105	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EB776_RS04110	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EB776_RS04130	COG0433	COG0433 Predicted ATPase
EB776_RS04145	COG0495	leucyl-tRNA aminoacylation
EB776_RS04170	COG0813	purine-nucleoside phosphorylase activity
EB776_RS04180	COG1435	thymidine kinase activity
EB776_RS04200	COG0803	Belongs to the bacterial solute-binding protein 9 family
EB776_RS04210	COG1121	(ABC) transporter
EB776_RS04215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EB776_RS04230	COG0671	phosphoesterase, PA-phosphatase related
EB776_RS04250	COG1113	amino acid transport
EB776_RS04255	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EB776_RS04255	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EB776_RS04265	COG2011	ABC-type metal ion transport system permease component
EB776_RS04270	COG1464	Belongs to the NlpA lipoprotein family
EB776_RS04275	COG1113	amino acid transport
EB776_RS04285	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EB776_RS04290	COG2186	Transcriptional regulator
EB776_RS04295	COG0477	Major facilitator Superfamily
EB776_RS04305	COG0826	peptidase U32
EB776_RS04310	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EB776_RS04315	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EB776_RS04320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB776_RS04360	COG0726	polysaccharide deacetylase
EB776_RS04365	COG0133	tryptophan synthase activity
EB776_RS04370	COG1609	Transcriptional regulator
EB776_RS04380	COG0738	Major facilitator superfamily
EB776_RS04385	COG0235	Class ii aldolase
EB776_RS04420	COG0406	alpha-ribazole phosphatase activity
EB776_RS04425	COG0799	negative regulation of ribosome biogenesis
EB776_RS04435	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EB776_RS04440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EB776_RS04450	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EB776_RS04460	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EB776_RS04465	COG1530	ribonuclease E activity
EB776_RS04470	COG1271	oxidase subunit
EB776_RS04475	COG1294	oxidase, subunit
EB776_RS04480	COG4988	ABC transporter
EB776_RS04485	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EB776_RS04495	COG1132	(ABC) transporter
EB776_RS04500	COG1132	(ABC) transporter
EB776_RS04520	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EB776_RS04525	COG0571	ribonuclease III activity
EB776_RS04540	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EB776_RS04555	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EB776_RS04565	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EB776_RS04575	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB776_RS04580	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EB776_RS04600	COG0438	transferase activity, transferring glycosyl groups
EB776_RS04615	COG4975	Glucose uptake
EB776_RS04620	COG0339	signal peptide processing
EB776_RS04675	COG0179	Fumarylacetoacetate (FAA) hydrolase
EB776_RS04705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EB776_RS04710	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EB776_RS04720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EB776_RS04730	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EB776_RS04755	COG2985	domain, Protein
EB776_RS04755	COG0569	domain protein
EB776_RS04770	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EB776_RS04855	COG1619	proteins homologs of microcin C7 resistance protein MccF
EB776_RS04870	COG0739	heme binding
EB776_RS04875	COG2177	Part of the ABC transporter FtsEX involved in
EB776_RS04880	COG2884	Cell division ATP-binding protein ftsE
EB776_RS04885	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EB776_RS04945	COG0513	Belongs to the DEAD box helicase family
EB776_RS04950	COG2095	MarC family integral membrane protein
EB776_RS04960	COG0006	proline dipeptidase activity
EB776_RS04965	COG2239	Acts as a magnesium transporter
EB776_RS04990	COG1611	Belongs to the LOG family
EB776_RS05000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB776_RS05005	COG1309	transcriptional regulator
EB776_RS05010	COG2814	Major facilitator Superfamily
EB776_RS05015	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EB776_RS05035	COG1079	Belongs to the binding-protein-dependent transport system permease family
EB776_RS05040	COG4603	Belongs to the binding-protein-dependent transport system permease family
EB776_RS05045	COG3845	ABC transporter
EB776_RS05050	COG1744	ABC transporter substrate-binding protein PnrA-like
EB776_RS05070	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EB776_RS05075	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EB776_RS05085	COG1268	BioY protein
EB776_RS05095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EB776_RS05100	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EB776_RS05105	COG4770	biotin carboxylase activity
EB776_RS05125	COG0644	oxidoreductase
EB776_RS05130	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EB776_RS05145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EB776_RS05150	COG2271	Major facilitator Superfamily
EB776_RS05155	COG2030	dehydratase
EB776_RS05185	COG0110	maltose O-acetyltransferase activity
EB776_RS05195	COG0039	L-malate dehydrogenase activity
EB776_RS05205	COG0166	Belongs to the GPI family
EB776_RS05210	COG0205	6-phosphofructokinase activity
EB776_RS05240	COG0045	succinate-CoA ligase (ADP-forming) activity
EB776_RS05245	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EB776_RS05245	COG2755	lipolytic protein G-D-S-L family
EB776_RS05295	COG4974	Belongs to the 'phage' integrase family
EB776_RS05320	COG0857	belongs to the CobB CobQ family
EB776_RS05320	COG0280	phosphate acetyltransferase
EB776_RS05325	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EB776_RS05340	COG1136	(ABC) transporter
EB776_RS05350	COG0114	fumarate hydratase activity
EB776_RS05355	COG0516	GMP reductase activity
EB776_RS05380	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EB776_RS05385	COG0151	Belongs to the GarS family
EB776_RS05390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EB776_RS05395	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EB776_RS05400	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EB776_RS05405	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EB776_RS05410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EB776_RS05420	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EB776_RS05430	COG0428	transporter
EB776_RS05435	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EB776_RS05440	COG0733	neurotransmitter:sodium symporter activity
EB776_RS05450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EB776_RS05455	COG1053	succinate dehydrogenase
EB776_RS05480	COG0802	atpase or kinase
EB776_RS05485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EB776_RS05495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EB776_RS05500	COG1072	(Pantothenic acid kinase))
EB776_RS05510	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EB776_RS05515	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EB776_RS05525	COG4720	Psort location CytoplasmicMembrane, score
EB776_RS05530	COG1122	ATPase activity
EB776_RS05550	COG0101	tRNA pseudouridine synthase activity
EB776_RS05555	COG1940	carbohydrate kinase activity
EB776_RS05565	COG0765	amino acid transport
EB776_RS05570	COG4598	ABC transporter
EB776_RS05575	COG0789	Transcriptional regulator
EB776_RS05580	COG1666	GTP binding
EB776_RS05585	COG0203	ribosomal protein L17
EB776_RS05590	COG0202	RNA polymerase activity
EB776_RS05600	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EB776_RS05605	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EB776_RS05610	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EB776_RS05620	COG0563	adenylate kinase activity
EB776_RS05630	COG0200	Binds to the 23S rRNA
EB776_RS05635	COG1841	ribosomal large subunit assembly
EB776_RS05640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EB776_RS05650	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EB776_RS05655	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EB776_RS05660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EB776_RS05665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EB776_RS05670	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EB776_RS05675	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EB776_RS05690	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EB776_RS05695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EB776_RS05700	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EB776_RS05705	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EB776_RS05710	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EB776_RS05715	COG0089	rRNA binding
EB776_RS05720	COG0088	Forms part of the polypeptide exit tunnel
EB776_RS05725	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EB776_RS05730	COG0051	transcription antitermination factor activity, RNA binding
EB776_RS05735	COG0546	phosphoglycolate phosphatase activity
EB776_RS05745	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EB776_RS05750	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EB776_RS05755	COG0049	tRNA binding
EB776_RS05760	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EB776_RS05765	COG0833	amino acid
EB776_RS05770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EB776_RS05775	COG0085	RNA polymerase activity
EB776_RS05780	COG0222	ribosome binding
EB776_RS05785	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EB776_RS05795	COG0081	regulation of translation
EB776_RS05800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EB776_RS05805	COG0250	Participates in transcription elongation, termination and antitermination
EB776_RS05820	COG0436	Aminotransferase
EB776_RS05830	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EB776_RS05845	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EB776_RS05855	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EB776_RS05875	COG1666	GTP binding
EB776_RS05885	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EB776_RS05890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EB776_RS05895	COG5401	PFAM Sporulation and spore germination
EB776_RS05900	COG5000	phosphorelay sensor kinase activity
EB776_RS05900	COG5002	protein histidine kinase activity
EB776_RS05905	COG0745	RESPONSE REGULATOR receiver
EB776_RS05925	COG0714	Associated with various cellular activities
EB776_RS05970	COG0483	inositol monophosphate 1-phosphatase activity
EB776_RS05985	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EB776_RS06080	COG0673	inositol 2-dehydrogenase activity
EB776_RS06105	COG1088	dTDP-glucose 4,6-dehydratase activity
EB776_RS06120	COG1316	TRANSCRIPTIONal
EB776_RS06125	COG1316	TRANSCRIPTIONal
EB776_RS06135	COG0642	Histidine kinase
EB776_RS06140	COG0745	RESPONSE REGULATOR receiver
EB776_RS06155	COG0424	maF-like protein
EB776_RS06190	COG1217	gtp-binding protein TYPA
EB776_RS06200	COG1132	(ABC) transporter
EB776_RS06230	COG0321	lipoyl(octanoyl) transferase activity
EB776_RS06235	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EB776_RS06245	COG1362	aminopeptidase activity
EB776_RS06260	COG2838	Isocitrate dehydrogenase
EB776_RS06265	COG2391	methyltransferase activity
EB776_RS06270	COG0425	Belongs to the sulfur carrier protein TusA family
EB776_RS06275	COG0366	Alpha amylase catalytic
EB776_RS06280	COG1501	Belongs to the glycosyl hydrolase 31 family
EB776_RS06290	COG0395	ABC-type sugar transport system, permease component
EB776_RS06295	COG1175	transmembrane transport
EB776_RS06300	COG1846	Transcriptional regulator
EB776_RS06300	COG1940	carbohydrate kinase activity
EB776_RS06325	COG1178	ABC-type Fe3 transport system permease component
EB776_RS06330	COG3842	ATPase activity
EB776_RS06335	COG1840	ABC-type Fe3 transport system, periplasmic component
EB776_RS06355	COG4608	Belongs to the ABC transporter superfamily
EB776_RS06360	COG0444	Belongs to the ABC transporter superfamily
EB776_RS06365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB776_RS06380	COG2116	formate transmembrane transporter activity
EB776_RS06390	COG0242	peptide deformylase activity
EB776_RS06395	COG1970	mechanosensitive ion channel activity
EB776_RS06420	COG0456	acetyltransferase
EB776_RS06420	COG1846	Transcriptional regulator
EB776_RS06425	COG1780	Probably involved in ribonucleotide reductase function
EB776_RS06435	COG0431	NADPH-dependent FMN reductase
EB776_RS06440	COG3226	Transcriptional regulator
EB776_RS06445	COG0477	Major facilitator Superfamily
EB776_RS06455	COG1834	amidinotransferase
EB776_RS06460	COG0549	Belongs to the carbamate kinase family
EB776_RS06465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EB776_RS06485	COG0395	ABC-type sugar transport system, permease component
EB776_RS06495	COG1653	transport
EB776_RS06500	COG0366	Alpha amylase catalytic
EB776_RS06515	COG0477	Major facilitator Superfamily
EB776_RS06545	COG0012	GTP binding
EB776_RS06550	COG1322	Protein conserved in bacteria
EB776_RS06555	COG1162	GTPase activity
EB776_RS06570	COG4555	ABC transporter
EB776_RS06590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EB776_RS06600	COG1722	exodeoxyribonuclease VII activity
EB776_RS06605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB776_RS06610	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EB776_RS06620	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EB776_RS06625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EB776_RS06630	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB776_RS06645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EB776_RS06650	COG1012	belongs to the aldehyde dehydrogenase family
EB776_RS06665	COG1131	(ABC) transporter
EB776_RS06670	COG1725	Transcriptional regulator
EB776_RS06695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EB776_RS06715	COG0148	phosphopyruvate hydratase activity
EB776_RS06730	COG0193	aminoacyl-tRNA hydrolase activity
EB776_RS06735	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EB776_RS06745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EB776_RS06755	COG1309	transcriptional regulator
EB776_RS06770	COG4152	abc transporter atp-binding protein
EB776_RS06775	COG1668	transmembrane transport
EB776_RS06785	COG0488	(ABC) transporter
EB776_RS06790	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EB776_RS06795	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EB776_RS06805	COG0084	hydrolase, TatD family'
EB776_RS06810	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB776_RS06815	COG1335	isochorismatase
EB776_RS06835	COG2873	o-acetylhomoserine
EB776_RS06855	COG1131	(ABC) transporter
EB776_RS06870	COG2813	Specifically methylates the guanine in position
EB776_RS06875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EB776_RS06900	COG1620	l-lactate permease
EB776_RS06905	COG0247	lactate metabolic process
EB776_RS06915	COG1556	Lactate utilization protein
EB776_RS06935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB776_RS06940	COG2190	(PTS) system
EB776_RS06945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB776_RS06945	COG1263	PTS System
EB776_RS06965	COG1051	belongs to the nudix hydrolase family
EB776_RS06975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EB776_RS06990	COG1511	domain protein
EB776_RS07000	COG2848	UPF0210 protein
EB776_RS07005	COG3830	Belongs to the UPF0237 family
EB776_RS07020	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EB776_RS07025	COG0254	rRNA binding
EB776_RS07030	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EB776_RS07035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EB776_RS07040	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EB776_RS07055	COG0477	Major facilitator Superfamily
EB776_RS07060	COG0657	acetylesterase activity
EB776_RS07065	COG2188	Transcriptional regulator
EB776_RS07070	COG1120	ATPase activity
EB776_RS07075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB776_RS07080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB776_RS07085	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EB776_RS07100	COG0596	Alpha beta hydrolase
EB776_RS07120	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EB776_RS07185	COG0791	NLP P60 protein
EB776_RS07185	COG1388	LysM domain
EB776_RS07195	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EB776_RS07200	COG2252	PERMEase
EB776_RS07215	COG1278	Cold shock
EB776_RS07225	COG1842	Phage shock protein A
EB776_RS07235	COG0745	RESPONSE REGULATOR receiver
EB776_RS07240	COG2205	protein histidine kinase activity
EB776_RS07250	COG4221	oxidoreductase activity
EB776_RS07265	COG0459	protein refolding
EB776_RS07280	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EB776_RS07320	COG3842	ATPase activity
EB776_RS07330	COG0673	inositol 2-dehydrogenase activity
EB776_RS07340	COG1653	transport
EB776_RS07345	COG1175	transmembrane transport
EB776_RS07375	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EB776_RS07390	COG1966	Carbon starvation protein
EB776_RS07415	COG2233	PERMEase
EB776_RS07430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB776_RS07435	COG0215	cysteine-tRNA ligase activity
EB776_RS07445	COG1136	(ABC) transporter
EB776_RS07470	COG2376	Dihydroxyacetone kinase
EB776_RS07485	COG3775	system Galactitol-specific IIC component
EB776_RS07515	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EB776_RS07520	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EB776_RS07535	COG5002	protein histidine kinase activity
EB776_RS07545	COG0588	phosphoglycerate mutase activity
EB776_RS07590	COG1120	ATPase activity
EB776_RS07595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB776_RS07625	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EB776_RS07630	COG0667	Aldo Keto reductase
EB776_RS07640	COG0710	3-dehydroquinate dehydratase activity
EB776_RS07670	COG0714	Associated with various cellular activities
EB776_RS07685	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EB776_RS07690	COG1950	PFAM Membrane protein of
EB776_RS07695	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EB776_RS07700	COG0586	Pfam SNARE associated Golgi protein
EB776_RS07735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EB776_RS07740	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB776_RS07745	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB776_RS07750	COG1120	ATPase activity
EB776_RS07770	COG1063	alcohol dehydrogenase
EB776_RS07775	COG2814	Major facilitator Superfamily
EB776_RS07785	COG0673	inositol 2-dehydrogenase activity
EB776_RS07795	COG0673	inositol 2-dehydrogenase activity
EB776_RS07800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EB776_RS07820	COG3718	enzyme involved in inositol metabolism
EB776_RS07825	COG3962	Belongs to the TPP enzyme family
EB776_RS07835	COG4604	ABC transporter, ATP-binding protein
EB776_RS07840	COG4605	iron ion homeostasis
EB776_RS07845	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB776_RS07850	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EB776_RS07855	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EB776_RS07860	COG0673	inositol 2-dehydrogenase activity
EB776_RS07870	COG1175	transmembrane transport
EB776_RS07875	COG0395	ABC-type sugar transport system, permease component
EB776_RS07880	COG1063	alcohol dehydrogenase
EB776_RS07885	COG0156	8-amino-7-oxononanoate synthase activity
EB776_RS07895	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EB776_RS07895	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EB776_RS07900	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EB776_RS07905	COG1904	glucuronate isomerase
EB776_RS07920	COG3142	Participates in the control of copper homeostasis
EB776_RS07935	COG1940	carbohydrate kinase activity
EB776_RS07945	COG0601	transmembrane transport
EB776_RS07950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB776_RS07960	COG1940	carbohydrate kinase activity
EB776_RS07965	COG1940	carbohydrate kinase activity
EB776_RS07965	COG1846	Transcriptional regulator
EB776_RS07975	COG1175	transmembrane transport
EB776_RS08010	COG2801	Transposase and inactivated derivatives
EB776_RS08050	COG2801	Transposase and inactivated derivatives
EB776_RS08055	COG1132	(ABC) transporter
EB776_RS08060	COG1132	(ABC) transporter
EB776_RS08060	COG2375	cellular response to nickel ion
EB776_RS08065	COG1129	ABC transporter
EB776_RS08070	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EB776_RS08085	COG0471	metal ion transport
EB776_RS08125	COG1252	NADH dehydrogenase
EB776_RS08130	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EB776_RS08175	COG1643	Atp-dependent helicase
EB776_RS08190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EB776_RS08225	COG0577	efflux transmembrane transporter activity
EB776_RS08230	COG1136	(ABC) transporter
EB776_RS08245	COG0745	RESPONSE REGULATOR receiver
EB776_RS08250	COG2205	protein histidine kinase activity
EB776_RS08255	COG0343	queuine tRNA-ribosyltransferase activity
EB776_RS08265	COG1428	Deoxynucleoside kinase
EB776_RS08305	COG0656	L-ascorbic acid biosynthetic process
EB776_RS08310	COG0351	phosphomethylpyrimidine kinase
EB776_RS08320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EB776_RS08330	COG2814	Major facilitator Superfamily
EB776_RS08335	COG0305	Participates in initiation and elongation during chromosome replication
EB776_RS08360	COG0359	binds to the 23S rRNA
EB776_RS08365	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EB776_RS08375	COG0360	Binds together with S18 to 16S ribosomal RNA
EB776_RS08380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EB776_RS08385	COG0628	permease
EB776_RS08395	COG0617	tRNA 3'-terminal CCA addition
EB776_RS08415	COG0492	ferredoxin-NADP+ reductase activity
EB776_RS08420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB776_RS08425	COG1181	Belongs to the D-alanine--D-alanine ligase family
EB776_RS08435	COG1192	Involved in chromosome partitioning
EB776_RS08440	COG0357	Ribosomal RNA small subunit methyltransferase G
EB776_RS08450	COG0706	membrane insertase activity
EB776_RS08455	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EB776_RS08460	COG0594	ribonuclease P activity
EB776_RS08465	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EB776_RS08470	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EB776_RS08475	COG0592	DNA-directed DNA polymerase activity
EB776_RS08480	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EB776_RS08490	COG0187	DNA topoisomerase II activity
EB776_RS08495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EB776_RS08535	COG0457	Tetratricopeptide repeat
EB776_RS08535	COG0705	Rhomboid family
EB776_RS08545	COG3764	Sortase (surface protein transpeptidase)
EB776_RS08570	COG1716	ATPase activity
EB776_RS08575	COG1131	(ABC) transporter
EB776_RS08575	COG1716	ATPase activity
EB776_RS08575	COG0842	Transport permease protein
EB776_RS08605	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EB776_RS08610	COG1854	S-ribosylhomocysteine lyase activity
EB776_RS08625	COG1780	Probably involved in ribonucleotide reductase function
EB776_RS08630	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EB776_RS08635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EB776_RS08645	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EB776_RS08650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EB776_RS08665	COG0395	ABC-type sugar transport system, permease component
EB776_RS08670	COG1175	transmembrane transport
EB776_RS08690	COG2072	flavoprotein involved in K transport
EB776_RS08700	COG1643	Atp-dependent helicase
EB776_RS08705	COG2197	response regulator
EB776_RS08710	COG4585	Histidine kinase
EB776_RS08720	COG1131	(ABC) transporter
EB776_RS08730	COG1136	(ABC) transporter
EB776_RS08740	COG2197	response regulator
EB776_RS08750	COG1328	CTP reductase activity
EB776_RS08770	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EB776_RS08775	COG1414	Transcriptional regulator
EB776_RS08780	COG0246	Mannitol dehydrogenase
EB776_RS08785	COG1312	Catalyzes the dehydration of D-mannonate
EB776_RS08790	COG0800	Aldolase
EB776_RS08795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EB776_RS08800	COG2226	methyltransferase
EB776_RS08810	COG1120	ATPase activity
EB776_RS08820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB776_RS08835	COG1132	(ABC) transporter
EB776_RS08840	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EB776_RS08845	COG1609	Transcriptional regulator
EB776_RS08860	COG1175	transmembrane transport
EB776_RS08865	COG0395	ABC-type sugar transport system, permease component
EB776_RS08900	COG1487	ribonuclease activity
EB776_RS08915	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EB776_RS08945	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB776_RS08950	COG1879	ABC-type sugar transport system periplasmic component
EB776_RS08985	COG0561	phosphatase activity
EB776_RS08990	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EB776_RS09005	COG0077	Prephenate dehydratase
EB776_RS09030	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EB776_RS09050	COG4868	Belongs to the UPF0371 family
EB776_RS09055	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EB776_RS09105	COG0521	Mo-molybdopterin cofactor biosynthetic process
EB776_RS09115	COG0315	cyclic pyranopterin monophosphate synthase activity
EB776_RS09125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EB776_RS09150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EB776_RS09180	COG0596	Alpha beta hydrolase
EB776_RS09225	COG1111	helicase
EB776_RS09225	COG1205	dead DEAH box helicase
EB776_RS09230	COG3655	Transcriptional regulator
EB776_RS09240	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EB776_RS09240	COG2890	protein-(glutamine-N5) methyltransferase activity
EB776_RS09245	COG1754	DNA topoisomerase type I activity
EB776_RS09245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EB776_RS09250	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EB776_RS09255	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EB776_RS09270	COG2801	Transposase and inactivated derivatives
EB776_RS09310	COG0717	Belongs to the dCTP deaminase family
EB776_RS09315	COG2111	Na H antiporter
EB776_RS09315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EB776_RS09320	COG1006	Multisubunit Na H antiporter MnhC subunit
EB776_RS09325	COG0651	ATP synthesis coupled electron transport
EB776_RS09355	COG4149	molybdate abc transporter
EB776_RS09360	COG3842	ATPase activity
EB776_RS09375	COG0662	Cupin 2, conserved barrel domain protein
EB776_RS09410	COG1940	carbohydrate kinase activity
EB776_RS09415	COG0390	transport system, permease component
EB776_RS09425	COG1505	serine-type exopeptidase activity
EB776_RS09435	COG0437	4 iron, 4 sulfur cluster binding
EB776_RS09440	COG0243	molybdopterin cofactor binding
EB776_RS09445	COG1937	Protein conserved in bacteria
EB776_RS09450	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB776_RS09460	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EB776_RS09465	COG0540	Belongs to the ATCase OTCase family
EB776_RS09470	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EB776_RS09475	COG0284	orotidine-5'-phosphate decarboxylase activity
EB776_RS09480	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EB776_RS09485	COG0167	dihydroorotate dehydrogenase activity
EB776_RS09490	COG0443	Heat shock 70 kDa protein
EB776_RS09495	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EB776_RS09500	COG0484	heat shock protein binding
EB776_RS09505	COG0789	Transcriptional regulator
EB776_RS09525	COG0584	glycerophosphoryl diester phosphodiesterase
EB776_RS09530	COG1506	peptidase
EB776_RS09530	COG0823	Involved in the tonB-independent uptake of proteins
EB776_RS09540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EB776_RS09570	COG1028	Short-chain dehydrogenase reductase Sdr
EB776_RS09585	COG0494	nUDIX hydrolase
EB776_RS09600	COG0191	fructose-bisphosphate aldolase activity
EB776_RS09610	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EB776_RS09615	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EB776_RS09620	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EB776_RS09625	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EB776_RS09655	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EB776_RS09685	COG0039	L-malate dehydrogenase activity
EB776_RS09690	COG0728	peptidoglycan biosynthetic process
EB776_RS09715	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EB776_RS09740	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EB776_RS09745	COG0406	alpha-ribazole phosphatase activity
EB776_RS09745	COG0494	nUDIX hydrolase
EB776_RS09765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EB776_RS09770	COG0306	phosphate transporter
EB776_RS09780	COG1115	amino acid carrier protein
EB776_RS09790	COG0737	Belongs to the 5'-nucleotidase family
EB776_RS09800	COG3485	protocatechuate 3,4-dioxygenase
EB776_RS09805	COG0354	folic acid binding
EB776_RS09815	COG1490	D-aminoacyl-tRNA deacylase activity
EB776_RS09835	COG0738	Major facilitator superfamily
EB776_RS09840	COG2390	Transcriptional regulator
EB776_RS09860	COG1349	DNA-binding transcription factor activity
EB776_RS09880	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EB776_RS09885	COG2376	Dihydroxyacetone kinase
EB776_RS09895	COG0698	ribose 5-phosphate isomerase
EB776_RS09900	COG0730	response to heat
EB776_RS09905	COG0641	radical SAM
EB776_RS09910	COG2814	Major facilitator Superfamily
EB776_RS09915	COG1609	Transcriptional regulator
EB776_RS09920	COG3119	arylsulfatase activity
EB776_RS09940	COG3842	ATPase activity
EB776_RS09945	COG1940	carbohydrate kinase activity
EB776_RS09950	COG2115	Belongs to the xylose isomerase family
EB776_RS09955	COG1070	Carbohydrate kinase
EB776_RS09960	COG1653	transport
EB776_RS09965	COG1175	transmembrane transport
EB776_RS09970	COG0395	ABC-type sugar transport system, permease component
EB776_RS09975	COG3119	arylsulfatase activity
EB776_RS09985	COG2390	Transcriptional regulator
EB776_RS09990	COG2610	gluconate transmembrane transporter activity
EB776_RS10010	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EB776_RS10015	COG3250	beta-galactosidase activity
EB776_RS10020	COG1869	D-ribose catabolic process
EB776_RS10030	COG1879	ABC-type sugar transport system periplasmic component
EB776_RS10035	COG1172	Belongs to the binding-protein-dependent transport system permease family
EB776_RS10040	COG1129	ABC transporter
EB776_RS10045	COG1609	Transcriptional regulator
EB776_RS10050	COG2226	methyltransferase
EB776_RS10055	COG1116	anion transmembrane transporter activity
EB776_RS10055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EB776_RS10075	COG0737	Belongs to the 5'-nucleotidase family
EB776_RS10085	COG1609	Transcriptional regulator
EB776_RS10090	COG2271	Major facilitator Superfamily
EB776_RS10095	COG1285	pathogenesis
EB776_RS10120	COG1131	(ABC) transporter
EB776_RS10155	COG1715	Restriction endonuclease
EB776_RS10170	COG2963	transposase activity
EB776_RS10195	COG1002	Type II restriction enzyme, methylase subunits
EB776_RS10240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EB776_RS10265	COG4824	toxin secretion phage lysis holin
EB776_RS10335	COG0740	serine-type endopeptidase activity
EB776_RS10340	COG4695	Portal protein
EB776_RS10345	COG4626	Terminase
EB776_RS10345	COG1802	Transcriptional regulator
EB776_RS10435	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EB776_RS10485	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EB776_RS10485	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity