locus-tag	class	description
EBQ10_RS00010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EBQ10_RS00020	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EBQ10_RS00025	COG0750	zinc metalloprotease
EBQ10_RS00030	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EBQ10_RS00040	COG0442	prolyl-tRNA aminoacylation
EBQ10_RS00050	COG0779	Required for maturation of 30S ribosomal subunits
EBQ10_RS00065	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EBQ10_RS00070	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EBQ10_RS00075	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EBQ10_RS00080	COG3852	Histidine kinase
EBQ10_RS00085	COG0745	RESPONSE REGULATOR receiver
EBQ10_RS00090	COG2271	Major facilitator Superfamily
EBQ10_RS00100	COG3842	ATPase activity
EBQ10_RS00130	COG0842	Transport permease protein
EBQ10_RS00130	COG1129	ABC transporter
EBQ10_RS00145	COG1185	polyribonucleotide nucleotidyltransferase activity
EBQ10_RS00155	COG0612	Peptidase, M16
EBQ10_RS00160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EBQ10_RS00165	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EBQ10_RS00180	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EBQ10_RS00185	COG1674	ftsk spoiiie
EBQ10_RS00200	COG1546	Belongs to the CinA family
EBQ10_RS00200	COG1058	Belongs to the CinA family
EBQ10_RS00205	COG1396	sequence-specific DNA binding
EBQ10_RS00215	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EBQ10_RS00220	COG2137	regulation of response to DNA damage stimulus
EBQ10_RS00225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EBQ10_RS00230	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EBQ10_RS00240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EBQ10_RS00250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EBQ10_RS00260	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EBQ10_RS00265	COG0318	PFAM AMP-dependent synthetase and ligase
EBQ10_RS00270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EBQ10_RS00290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EBQ10_RS00300	COG2001	Belongs to the MraZ family
EBQ10_RS00305	COG0275	rRNA processing
EBQ10_RS00315	COG0768	penicillin binding
EBQ10_RS00320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EBQ10_RS00325	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EBQ10_RS00330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EBQ10_RS00335	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EBQ10_RS00345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EBQ10_RS00350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EBQ10_RS00360	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EBQ10_RS00370	COG1799	cell septum assembly
EBQ10_RS00385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EBQ10_RS00400	COG0587	DNA-directed DNA polymerase activity
EBQ10_RS00415	COG0735	belongs to the Fur family
EBQ10_RS00420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EBQ10_RS00425	COG1121	(ABC) transporter
EBQ10_RS00435	COG0423	glycine-tRNA ligase activity
EBQ10_RS00460	COG0358	DNA primase activity
EBQ10_RS00470	COG0805	protein transport
EBQ10_RS00475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EBQ10_RS00510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBQ10_RS00515	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EBQ10_RS00550	COG1090	epimerase
EBQ10_RS00570	COG0009	L-threonylcarbamoyladenylate synthase
EBQ10_RS00590	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EBQ10_RS00615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EBQ10_RS00620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EBQ10_RS00625	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EBQ10_RS00635	COG3022	response to hydroperoxide
EBQ10_RS00645	COG1940	carbohydrate kinase activity
EBQ10_RS00660	COG0174	glutamine synthetase
EBQ10_RS00665	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EBQ10_RS00675	COG0174	glutamine synthetase
EBQ10_RS00695	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBQ10_RS00700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBQ10_RS00710	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EBQ10_RS00725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBQ10_RS00765	COG0205	6-phosphofructokinase activity
EBQ10_RS00770	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
EBQ10_RS00775	COG2815	serine threonine protein kinase
EBQ10_RS00775	COG0515	serine threonine protein kinase
EBQ10_RS00790	COG0142	geranyltranstransferase activity
EBQ10_RS00805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EBQ10_RS00810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EBQ10_RS00810	COG1199	ATP-dependent helicase activity
EBQ10_RS00820	COG0187	DNA topoisomerase II activity
EBQ10_RS00835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EBQ10_RS00875	COG0569	domain protein
EBQ10_RS00890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EBQ10_RS00900	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EBQ10_RS00950	COG4412	M6 family metalloprotease domain protein
EBQ10_RS00950	COG1404	Belongs to the peptidase S8 family
EBQ10_RS00970	COG2197	response regulator
EBQ10_RS00975	COG1760	l-serine dehydratase
EBQ10_RS00980	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EBQ10_RS00985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EBQ10_RS00995	COG0438	transferase activity, transferring glycosyl groups
EBQ10_RS01005	COG1051	belongs to the nudix hydrolase family
EBQ10_RS01010	COG0217	transcriptional regulatory protein
EBQ10_RS01015	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EBQ10_RS01020	COG0632	four-way junction helicase activity
EBQ10_RS01025	COG2255	four-way junction helicase activity
EBQ10_RS01035	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBQ10_RS01040	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EBQ10_RS01045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EBQ10_RS01050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EBQ10_RS01060	COG1196	nuclear chromosome segregation
EBQ10_RS01065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBQ10_RS01070	COG0124	histidyl-tRNA synthetase
EBQ10_RS01075	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EBQ10_RS01080	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EBQ10_RS01100	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EBQ10_RS01115	COG2409	Drug exporters of the RND superfamily
EBQ10_RS01125	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EBQ10_RS01135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EBQ10_RS01140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EBQ10_RS01160	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EBQ10_RS01170	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EBQ10_RS01175	COG2217	Heavy metal translocating P-type atpase
EBQ10_RS01180	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EBQ10_RS01185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EBQ10_RS01190	COG0505	Belongs to the CarA family
EBQ10_RS01195	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EBQ10_RS01205	COG0194	GDP metabolic process
EBQ10_RS01210	COG1758	RNA polymerase activity
EBQ10_RS01220	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBQ10_RS01225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EBQ10_RS01230	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EBQ10_RS01240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EBQ10_RS01245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EBQ10_RS01250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EBQ10_RS01255	COG0140	phosphoribosyl-ATP diphosphatase activity
EBQ10_RS01260	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EBQ10_RS01290	COG4581	dead DEAH box helicase
EBQ10_RS01300	COG1216	Glycosyl transferase, family 2
EBQ10_RS01345	COG0205	6-phosphofructokinase activity
EBQ10_RS01350	COG1160	GTP binding
EBQ10_RS01355	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EBQ10_RS01365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EBQ10_RS01390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBQ10_RS01405	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EBQ10_RS01410	COG0149	triose-phosphate isomerase activity
EBQ10_RS01415	COG0126	phosphoglycerate kinase activity
EBQ10_RS01420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EBQ10_RS01425	COG1481	regulation of sporulation
EBQ10_RS01440	COG0322	excinuclease ABC activity
EBQ10_RS01465	COG0556	nucleotide-excision repair
EBQ10_RS01470	COG0237	dephospho-CoA kinase activity
EBQ10_RS01475	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EBQ10_RS01480	COG1136	(ABC) transporter
EBQ10_RS01490	COG0539	negative regulation of cytoplasmic translation
EBQ10_RS01515	COG0469	pyruvate kinase activity
EBQ10_RS01520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EBQ10_RS01525	COG0134	indole-3-glycerol-phosphate synthase activity
EBQ10_RS01535	COG0107	imidazoleglycerol-phosphate synthase activity
EBQ10_RS01550	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EBQ10_RS01560	COG4122	O-methyltransferase activity
EBQ10_RS01565	COG1222	aaa ATPase
EBQ10_RS01585	COG1968	undecaprenyl-diphosphatase activity
EBQ10_RS01600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EBQ10_RS01610	COG0519	Catalyzes the synthesis of GMP from XMP
EBQ10_RS01610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EBQ10_RS01635	COG0587	DNA-directed DNA polymerase activity
EBQ10_RS01650	COG1881	PFAM PEBP family protein
EBQ10_RS01685	COG1119	ATPase activity
EBQ10_RS01690	COG0297	glycogen (starch) synthase activity
EBQ10_RS01700	COG1136	(ABC) transporter
EBQ10_RS01710	COG3830	Belongs to the UPF0237 family
EBQ10_RS01710	COG0560	Phosphoserine phosphatase
EBQ10_RS01720	COG0488	(ABC) transporter
EBQ10_RS01725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EBQ10_RS01730	COG2151	metal-sulfur cluster biosynthetic enzyme
EBQ10_RS01745	COG0396	ATPase activity
EBQ10_RS01775	COG0728	peptidoglycan biosynthetic process
EBQ10_RS01795	COG0497	DNA recombination
EBQ10_RS01800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EBQ10_RS01810	COG0647	UMP catabolic process
EBQ10_RS01840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EBQ10_RS01845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EBQ10_RS01850	COG1121	(ABC) transporter
EBQ10_RS01855	COG0803	Belongs to the bacterial solute-binding protein 9 family
EBQ10_RS01860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EBQ10_RS01865	COG1131	(ABC) transporter
EBQ10_RS01875	COG1476	TRANSCRIPTIONal
EBQ10_RS01885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EBQ10_RS01890	COG1438	arginine binding
EBQ10_RS01905	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EBQ10_RS01910	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EBQ10_RS01930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBQ10_RS01945	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EBQ10_RS01950	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EBQ10_RS01960	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EBQ10_RS01965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EBQ10_RS01975	COG0131	Imidazoleglycerol-phosphate dehydratase
EBQ10_RS01985	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EBQ10_RS01990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EBQ10_RS01995	COG1381	Involved in DNA repair and RecF pathway recombination
EBQ10_RS02000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EBQ10_RS02035	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EBQ10_RS02045	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EBQ10_RS02050	COG0484	heat shock protein binding
EBQ10_RS02055	COG1420	regulation of RNA biosynthetic process
EBQ10_RS02075	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EBQ10_RS02080	COG0481	GTPase activity
EBQ10_RS02105	COG0268	Binds directly to 16S ribosomal RNA
EBQ10_RS02110	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EBQ10_RS02115	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EBQ10_RS02135	COG0433	COG0433 Predicted ATPase
EBQ10_RS02150	COG0495	leucyl-tRNA aminoacylation
EBQ10_RS02175	COG0813	purine-nucleoside phosphorylase activity
EBQ10_RS02185	COG1435	thymidine kinase activity
EBQ10_RS02205	COG0803	Belongs to the bacterial solute-binding protein 9 family
EBQ10_RS02215	COG1121	(ABC) transporter
EBQ10_RS02220	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EBQ10_RS02235	COG0671	phosphoesterase, PA-phosphatase related
EBQ10_RS02245	COG1395	domain, Protein
EBQ10_RS02255	COG1113	amino acid transport
EBQ10_RS02260	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EBQ10_RS02260	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EBQ10_RS02270	COG2011	ABC-type metal ion transport system permease component
EBQ10_RS02275	COG1464	Belongs to the NlpA lipoprotein family
EBQ10_RS02280	COG1113	amino acid transport
EBQ10_RS02290	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EBQ10_RS02295	COG0826	peptidase U32
EBQ10_RS02310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBQ10_RS02365	COG0726	polysaccharide deacetylase
EBQ10_RS02370	COG0133	tryptophan synthase activity
EBQ10_RS02375	COG1609	Transcriptional regulator
EBQ10_RS02385	COG0738	Major facilitator superfamily
EBQ10_RS02390	COG0235	Class ii aldolase
EBQ10_RS02425	COG0406	alpha-ribazole phosphatase activity
EBQ10_RS02430	COG0799	negative regulation of ribosome biogenesis
EBQ10_RS02440	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EBQ10_RS02445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EBQ10_RS02455	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EBQ10_RS02465	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EBQ10_RS02470	COG1530	ribonuclease E activity
EBQ10_RS02475	COG1271	oxidase subunit
EBQ10_RS02480	COG1294	oxidase, subunit
EBQ10_RS02485	COG4988	ABC transporter
EBQ10_RS02490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBQ10_RS02500	COG1132	(ABC) transporter
EBQ10_RS02505	COG1132	(ABC) transporter
EBQ10_RS02525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EBQ10_RS02530	COG0571	ribonuclease III activity
EBQ10_RS02545	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EBQ10_RS02560	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EBQ10_RS02570	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EBQ10_RS02580	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBQ10_RS02585	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EBQ10_RS02605	COG0438	transferase activity, transferring glycosyl groups
EBQ10_RS02615	COG4975	Glucose uptake
EBQ10_RS02620	COG0339	signal peptide processing
EBQ10_RS02675	COG0179	Fumarylacetoacetate (FAA) hydrolase
EBQ10_RS02680	COG1022	Amp-dependent synthetase and ligase
EBQ10_RS02705	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EBQ10_RS02710	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EBQ10_RS02720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EBQ10_RS02730	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EBQ10_RS02755	COG0569	domain protein
EBQ10_RS02755	COG2985	domain, Protein
EBQ10_RS02770	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EBQ10_RS02845	COG1846	Transcriptional regulator
EBQ10_RS02850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EBQ10_RS03130	COG1619	proteins homologs of microcin C7 resistance protein MccF
EBQ10_RS03145	COG0739	heme binding
EBQ10_RS03150	COG2177	Part of the ABC transporter FtsEX involved in
EBQ10_RS03155	COG2884	Cell division ATP-binding protein ftsE
EBQ10_RS03160	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EBQ10_RS03220	COG0513	Belongs to the DEAD box helicase family
EBQ10_RS03225	COG2095	MarC family integral membrane protein
EBQ10_RS03235	COG0006	proline dipeptidase activity
EBQ10_RS03240	COG2239	Acts as a magnesium transporter
EBQ10_RS03265	COG1611	Belongs to the LOG family
EBQ10_RS03275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EBQ10_RS03280	COG1309	transcriptional regulator
EBQ10_RS03285	COG2814	Major facilitator Superfamily
EBQ10_RS03290	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EBQ10_RS03310	COG1079	Belongs to the binding-protein-dependent transport system permease family
EBQ10_RS03315	COG4603	Belongs to the binding-protein-dependent transport system permease family
EBQ10_RS03320	COG3845	ABC transporter
EBQ10_RS03325	COG1744	ABC transporter substrate-binding protein PnrA-like
EBQ10_RS03330	COG0662	Cupin 2, conserved barrel domain protein
EBQ10_RS03330	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EBQ10_RS03345	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EBQ10_RS03350	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EBQ10_RS03360	COG1268	BioY protein
EBQ10_RS03365	COG0736	holo-[acyl-carrier-protein] synthase activity
EBQ10_RS03370	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EBQ10_RS03375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EBQ10_RS03380	COG4770	biotin carboxylase activity
EBQ10_RS03400	COG0644	oxidoreductase
EBQ10_RS03405	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EBQ10_RS03420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EBQ10_RS03425	COG2271	Major facilitator Superfamily
EBQ10_RS03460	COG0110	maltose O-acetyltransferase activity
EBQ10_RS03470	COG0039	L-malate dehydrogenase activity
EBQ10_RS03485	COG2826	transposase and inactivated derivatives, IS30 family
EBQ10_RS03490	COG2826	transposase and inactivated derivatives, IS30 family
EBQ10_RS03535	COG0166	Belongs to the GPI family
EBQ10_RS03540	COG0205	6-phosphofructokinase activity
EBQ10_RS03570	COG0045	succinate-CoA ligase (ADP-forming) activity
EBQ10_RS03575	COG2755	lipolytic protein G-D-S-L family
EBQ10_RS03575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EBQ10_RS03585	COG0653	protein targeting
EBQ10_RS03625	COG1484	DNA-dependent DNA replication
EBQ10_RS03640	COG3505	Type IV secretory pathway VirD4
EBQ10_RS03660	COG0791	NLP P60 protein
EBQ10_RS03730	COG2226	methyltransferase
EBQ10_RS03765	COG1192	Involved in chromosome partitioning
EBQ10_RS03770	COG0792	nuclease activity
EBQ10_RS03780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EBQ10_RS03840	COG4974	Belongs to the 'phage' integrase family
EBQ10_RS03865	COG0857	belongs to the CobB CobQ family
EBQ10_RS03865	COG0280	phosphate acetyltransferase
EBQ10_RS03870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EBQ10_RS03885	COG1136	(ABC) transporter
EBQ10_RS03895	COG0114	fumarate hydratase activity
EBQ10_RS03900	COG0516	GMP reductase activity
EBQ10_RS03925	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EBQ10_RS03930	COG0151	Belongs to the GarS family
EBQ10_RS03935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EBQ10_RS03940	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EBQ10_RS03945	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EBQ10_RS03950	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EBQ10_RS03955	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EBQ10_RS03965	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EBQ10_RS03975	COG0428	transporter
EBQ10_RS03980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EBQ10_RS03985	COG0733	neurotransmitter:sodium symporter activity
EBQ10_RS03995	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EBQ10_RS04000	COG1053	succinate dehydrogenase
EBQ10_RS04025	COG0802	atpase or kinase
EBQ10_RS04030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EBQ10_RS04040	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EBQ10_RS04045	COG1072	(Pantothenic acid kinase))
EBQ10_RS04055	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EBQ10_RS04060	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EBQ10_RS04070	COG4720	Psort location CytoplasmicMembrane, score
EBQ10_RS04075	COG1122	ATPase activity
EBQ10_RS04095	COG0101	tRNA pseudouridine synthase activity
EBQ10_RS04100	COG1940	carbohydrate kinase activity
EBQ10_RS04110	COG0765	amino acid transport
EBQ10_RS04115	COG4598	ABC transporter
EBQ10_RS04120	COG0789	Transcriptional regulator
EBQ10_RS04130	COG1666	GTP binding
EBQ10_RS04135	COG0203	ribosomal protein L17
EBQ10_RS04140	COG0202	RNA polymerase activity
EBQ10_RS04150	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EBQ10_RS04155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EBQ10_RS04160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EBQ10_RS04170	COG0563	adenylate kinase activity
EBQ10_RS04180	COG0200	Binds to the 23S rRNA
EBQ10_RS04185	COG1841	ribosomal large subunit assembly
EBQ10_RS04190	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EBQ10_RS04200	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EBQ10_RS04205	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EBQ10_RS04210	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EBQ10_RS04215	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EBQ10_RS04220	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EBQ10_RS04225	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EBQ10_RS04240	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EBQ10_RS04245	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EBQ10_RS04250	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EBQ10_RS04255	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EBQ10_RS04260	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EBQ10_RS04265	COG0089	rRNA binding
EBQ10_RS04270	COG0088	Forms part of the polypeptide exit tunnel
EBQ10_RS04275	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EBQ10_RS04280	COG0051	transcription antitermination factor activity, RNA binding
EBQ10_RS04285	COG0546	phosphoglycolate phosphatase activity
EBQ10_RS04295	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EBQ10_RS04300	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EBQ10_RS04305	COG0049	tRNA binding
EBQ10_RS04310	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EBQ10_RS04315	COG0833	amino acid
EBQ10_RS04320	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EBQ10_RS04325	COG0085	RNA polymerase activity
EBQ10_RS04330	COG0222	ribosome binding
EBQ10_RS04335	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EBQ10_RS04345	COG0081	regulation of translation
EBQ10_RS04350	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EBQ10_RS04355	COG0250	Participates in transcription elongation, termination and antitermination
EBQ10_RS04370	COG0436	Aminotransferase
EBQ10_RS04380	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EBQ10_RS04395	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EBQ10_RS04405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EBQ10_RS04425	COG1666	GTP binding
EBQ10_RS04435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EBQ10_RS04440	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EBQ10_RS04445	COG5401	PFAM Sporulation and spore germination
EBQ10_RS04450	COG5000	phosphorelay sensor kinase activity
EBQ10_RS04450	COG5002	protein histidine kinase activity
EBQ10_RS04455	COG0745	RESPONSE REGULATOR receiver
EBQ10_RS04475	COG0714	Associated with various cellular activities
EBQ10_RS04520	COG0483	inositol monophosphate 1-phosphatase activity
EBQ10_RS04535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EBQ10_RS04580	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EBQ10_RS04630	COG0673	inositol 2-dehydrogenase activity
EBQ10_RS04655	COG1088	dTDP-glucose 4,6-dehydratase activity
EBQ10_RS04670	COG1316	TRANSCRIPTIONal
EBQ10_RS04675	COG1316	TRANSCRIPTIONal
EBQ10_RS04685	COG0642	Histidine kinase
EBQ10_RS04690	COG0745	RESPONSE REGULATOR receiver
EBQ10_RS04705	COG0424	maF-like protein
EBQ10_RS04740	COG1217	gtp-binding protein TYPA
EBQ10_RS04750	COG1132	(ABC) transporter
EBQ10_RS04780	COG0321	lipoyl(octanoyl) transferase activity
EBQ10_RS04785	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EBQ10_RS04795	COG1362	aminopeptidase activity
EBQ10_RS04810	COG2838	Isocitrate dehydrogenase
EBQ10_RS04815	COG2391	methyltransferase activity
EBQ10_RS04820	COG0425	Belongs to the sulfur carrier protein TusA family
EBQ10_RS04825	COG0366	Alpha amylase catalytic
EBQ10_RS04830	COG1501	Belongs to the glycosyl hydrolase 31 family
EBQ10_RS04840	COG0395	ABC-type sugar transport system, permease component
EBQ10_RS04845	COG1175	transmembrane transport
EBQ10_RS04850	COG1846	Transcriptional regulator
EBQ10_RS04850	COG1940	carbohydrate kinase activity
EBQ10_RS04875	COG1178	ABC-type Fe3 transport system permease component
EBQ10_RS04885	COG1840	ABC-type Fe3 transport system, periplasmic component
EBQ10_RS04910	COG4608	Belongs to the ABC transporter superfamily
EBQ10_RS04915	COG0444	Belongs to the ABC transporter superfamily
EBQ10_RS04920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EBQ10_RS04935	COG2116	formate transmembrane transporter activity
EBQ10_RS04945	COG0242	peptide deformylase activity
EBQ10_RS04950	COG1970	mechanosensitive ion channel activity
EBQ10_RS04975	COG1780	Probably involved in ribonucleotide reductase function
EBQ10_RS04985	COG0431	NADPH-dependent FMN reductase
EBQ10_RS04990	COG3226	Transcriptional regulator
EBQ10_RS05005	COG1834	amidinotransferase
EBQ10_RS05010	COG0549	Belongs to the carbamate kinase family
EBQ10_RS05015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EBQ10_RS05035	COG0395	ABC-type sugar transport system, permease component
EBQ10_RS05040	COG1175	transmembrane transport
EBQ10_RS05050	COG0366	Alpha amylase catalytic
EBQ10_RS05065	COG0477	Major facilitator Superfamily
EBQ10_RS05090	COG0012	GTP binding
EBQ10_RS05095	COG1322	Protein conserved in bacteria
EBQ10_RS05100	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EBQ10_RS05110	COG1722	exodeoxyribonuclease VII activity
EBQ10_RS05115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBQ10_RS05120	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EBQ10_RS05130	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EBQ10_RS05135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EBQ10_RS05140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBQ10_RS05155	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EBQ10_RS05160	COG1012	belongs to the aldehyde dehydrogenase family
EBQ10_RS05175	COG1131	(ABC) transporter
EBQ10_RS05180	COG1725	Transcriptional regulator
EBQ10_RS05225	COG0148	phosphopyruvate hydratase activity
EBQ10_RS05240	COG0193	aminoacyl-tRNA hydrolase activity
EBQ10_RS05245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EBQ10_RS05255	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EBQ10_RS05265	COG1309	transcriptional regulator
EBQ10_RS05280	COG4152	abc transporter atp-binding protein
EBQ10_RS05285	COG1668	transmembrane transport
EBQ10_RS05295	COG0488	(ABC) transporter
EBQ10_RS05300	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EBQ10_RS05305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EBQ10_RS05315	COG0084	hydrolase, TatD family'
EBQ10_RS05320	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EBQ10_RS05350	COG1335	isochorismatase
EBQ10_RS05370	COG2873	o-acetylhomoserine
EBQ10_RS05390	COG1131	(ABC) transporter
EBQ10_RS05405	COG2813	Specifically methylates the guanine in position
EBQ10_RS05410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EBQ10_RS05435	COG1620	l-lactate permease
EBQ10_RS05440	COG0247	lactate metabolic process
EBQ10_RS05450	COG1556	Lactate utilization protein
EBQ10_RS05470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBQ10_RS05475	COG2190	(PTS) system
EBQ10_RS05480	COG1263	PTS System
EBQ10_RS05480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EBQ10_RS05500	COG1051	belongs to the nudix hydrolase family
EBQ10_RS05510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBQ10_RS05525	COG1511	domain protein
EBQ10_RS05535	COG2848	UPF0210 protein
EBQ10_RS05540	COG3830	Belongs to the UPF0237 family
EBQ10_RS05555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EBQ10_RS05560	COG0254	rRNA binding
EBQ10_RS05565	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EBQ10_RS05570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EBQ10_RS05575	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EBQ10_RS05590	COG0477	Major facilitator Superfamily
EBQ10_RS05595	COG0657	acetylesterase activity
EBQ10_RS05600	COG2188	Transcriptional regulator
EBQ10_RS05605	COG1120	ATPase activity
EBQ10_RS05610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBQ10_RS05615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBQ10_RS05620	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EBQ10_RS05635	COG0596	Alpha beta hydrolase
EBQ10_RS05650	COG3657	addiction module killer protein
EBQ10_RS05655	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EBQ10_RS05720	COG1388	LysM domain
EBQ10_RS05720	COG0791	NLP P60 protein
EBQ10_RS05730	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EBQ10_RS05735	COG2252	PERMEase
EBQ10_RS05750	COG1278	Cold shock
EBQ10_RS05760	COG1842	Phage shock protein A
EBQ10_RS05770	COG0745	RESPONSE REGULATOR receiver
EBQ10_RS05775	COG2205	protein histidine kinase activity
EBQ10_RS05785	COG4221	oxidoreductase activity
EBQ10_RS05795	COG0459	protein refolding
EBQ10_RS05810	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EBQ10_RS05835	COG1131	(ABC) transporter
EBQ10_RS05860	COG3842	ATPase activity
EBQ10_RS05870	COG0673	inositol 2-dehydrogenase activity
EBQ10_RS05880	COG1653	transport
EBQ10_RS05885	COG1175	transmembrane transport
EBQ10_RS05915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EBQ10_RS05930	COG1966	Carbon starvation protein
EBQ10_RS05955	COG2233	PERMEase
EBQ10_RS05970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EBQ10_RS05975	COG0215	cysteine-tRNA ligase activity
EBQ10_RS05985	COG1136	(ABC) transporter
EBQ10_RS06000	COG2376	Dihydroxyacetone kinase
EBQ10_RS06015	COG3775	system Galactitol-specific IIC component
EBQ10_RS06035	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EBQ10_RS06040	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EBQ10_RS06055	COG5002	protein histidine kinase activity
EBQ10_RS06065	COG0588	phosphoglycerate mutase activity
EBQ10_RS06105	COG1609	Transcriptional regulator
EBQ10_RS06115	COG1175	transmembrane transport
EBQ10_RS06120	COG0395	ABC-type sugar transport system, permease component
EBQ10_RS06140	COG1120	ATPase activity
EBQ10_RS06145	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBQ10_RS06165	COG3345	alpha-galactosidase
EBQ10_RS06175	COG0395	ABC-type sugar transport system, permease component
EBQ10_RS06180	COG1175	transmembrane transport
EBQ10_RS06210	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EBQ10_RS06215	COG0667	Aldo Keto reductase
EBQ10_RS06240	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EBQ10_RS06245	COG1950	PFAM Membrane protein of
EBQ10_RS06250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EBQ10_RS06255	COG0586	Pfam SNARE associated Golgi protein
EBQ10_RS06290	COG1309	transcriptional regulator
EBQ10_RS06300	COG1132	(ABC) transporter
EBQ10_RS06305	COG1129	ABC transporter
EBQ10_RS06325	COG1063	alcohol dehydrogenase
EBQ10_RS06330	COG1609	Transcriptional regulator
EBQ10_RS06335	COG2271	Major facilitator Superfamily
EBQ10_RS06340	COG0483	inositol monophosphate 1-phosphatase activity
EBQ10_RS06345	COG1879	ABC-type sugar transport system periplasmic component
EBQ10_RS06350	COG1172	Belongs to the binding-protein-dependent transport system permease family
EBQ10_RS06360	COG0673	inositol 2-dehydrogenase activity
EBQ10_RS06370	COG0673	inositol 2-dehydrogenase activity
EBQ10_RS06375	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EBQ10_RS06395	COG3718	enzyme involved in inositol metabolism
EBQ10_RS06400	COG3962	Belongs to the TPP enzyme family
EBQ10_RS06410	COG4604	ABC transporter, ATP-binding protein
EBQ10_RS06415	COG4605	iron ion homeostasis
EBQ10_RS06420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBQ10_RS06425	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EBQ10_RS06430	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EBQ10_RS06440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EBQ10_RS06440	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EBQ10_RS06445	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EBQ10_RS06450	COG1904	glucuronate isomerase
EBQ10_RS06465	COG3142	Participates in the control of copper homeostasis
EBQ10_RS06480	COG1940	carbohydrate kinase activity
EBQ10_RS06490	COG0601	transmembrane transport
EBQ10_RS06495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EBQ10_RS06505	COG1940	carbohydrate kinase activity
EBQ10_RS06510	COG1846	Transcriptional regulator
EBQ10_RS06510	COG1940	carbohydrate kinase activity
EBQ10_RS06520	COG1175	transmembrane transport
EBQ10_RS06565	COG1132	(ABC) transporter
EBQ10_RS06570	COG1132	(ABC) transporter
EBQ10_RS06570	COG2375	cellular response to nickel ion
EBQ10_RS06575	COG1129	ABC transporter
EBQ10_RS06580	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EBQ10_RS06595	COG0471	metal ion transport
EBQ10_RS06625	COG1129	ABC transporter
EBQ10_RS06630	COG1172	Belongs to the binding-protein-dependent transport system permease family
EBQ10_RS06640	COG1879	ABC-type sugar transport system periplasmic component
EBQ10_RS06650	COG1070	Carbohydrate kinase
EBQ10_RS06675	COG1252	NADH dehydrogenase
EBQ10_RS06720	COG1643	Atp-dependent helicase
EBQ10_RS06735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EBQ10_RS06765	COG0577	efflux transmembrane transporter activity
EBQ10_RS06770	COG1136	(ABC) transporter
EBQ10_RS06785	COG0745	RESPONSE REGULATOR receiver
EBQ10_RS06790	COG2205	protein histidine kinase activity
EBQ10_RS06795	COG0343	queuine tRNA-ribosyltransferase activity
EBQ10_RS06805	COG1428	Deoxynucleoside kinase
EBQ10_RS06850	COG0351	phosphomethylpyrimidine kinase
EBQ10_RS06860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EBQ10_RS06870	COG2814	Major facilitator Superfamily
EBQ10_RS06875	COG0305	Participates in initiation and elongation during chromosome replication
EBQ10_RS06890	COG0737	Belongs to the 5'-nucleotidase family
EBQ10_RS06895	COG0359	binds to the 23S rRNA
EBQ10_RS06900	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EBQ10_RS06910	COG0360	Binds together with S18 to 16S ribosomal RNA
EBQ10_RS06915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBQ10_RS06920	COG0628	permease
EBQ10_RS06930	COG0617	tRNA 3'-terminal CCA addition
EBQ10_RS06950	COG0492	ferredoxin-NADP+ reductase activity
EBQ10_RS06955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBQ10_RS06960	COG1181	Belongs to the D-alanine--D-alanine ligase family
EBQ10_RS06970	COG1192	Involved in chromosome partitioning
EBQ10_RS06975	COG0357	Ribosomal RNA small subunit methyltransferase G
EBQ10_RS06985	COG0706	membrane insertase activity
EBQ10_RS06990	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EBQ10_RS06995	COG0594	ribonuclease P activity
EBQ10_RS07000	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EBQ10_RS07005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EBQ10_RS07010	COG0592	DNA-directed DNA polymerase activity
EBQ10_RS07015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EBQ10_RS07025	COG0187	DNA topoisomerase II activity
EBQ10_RS07030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EBQ10_RS07070	COG0705	Rhomboid family
EBQ10_RS07080	COG3764	Sortase (surface protein transpeptidase)
EBQ10_RS07110	COG1716	ATPase activity
EBQ10_RS07110	COG1131	(ABC) transporter
EBQ10_RS07110	COG0842	Transport permease protein
EBQ10_RS07140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EBQ10_RS07145	COG1854	S-ribosylhomocysteine lyase activity
EBQ10_RS07160	COG1780	Probably involved in ribonucleotide reductase function
EBQ10_RS07165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBQ10_RS07170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EBQ10_RS07180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EBQ10_RS07185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EBQ10_RS07200	COG0395	ABC-type sugar transport system, permease component
EBQ10_RS07205	COG1175	transmembrane transport
EBQ10_RS07225	COG2072	flavoprotein involved in K transport
EBQ10_RS07235	COG1643	Atp-dependent helicase
EBQ10_RS07240	COG2197	response regulator
EBQ10_RS07245	COG4585	Histidine kinase
EBQ10_RS07255	COG1131	(ABC) transporter
EBQ10_RS07265	COG1136	(ABC) transporter
EBQ10_RS07275	COG2197	response regulator
EBQ10_RS07285	COG1328	CTP reductase activity
EBQ10_RS07305	COG1126	abc transporter atp-binding protein
EBQ10_RS07310	COG1414	Transcriptional regulator
EBQ10_RS07315	COG0246	Mannitol dehydrogenase
EBQ10_RS07320	COG1312	Catalyzes the dehydration of D-mannonate
EBQ10_RS07325	COG0800	Aldolase
EBQ10_RS07330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBQ10_RS07335	COG2226	methyltransferase
EBQ10_RS07345	COG1120	ATPase activity
EBQ10_RS07355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EBQ10_RS07370	COG1132	(ABC) transporter
EBQ10_RS07375	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EBQ10_RS07380	COG1609	Transcriptional regulator
EBQ10_RS07395	COG1175	transmembrane transport
EBQ10_RS07400	COG0395	ABC-type sugar transport system, permease component
EBQ10_RS07410	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EBQ10_RS07440	COG0732	type I restriction modification DNA specificity domain
EBQ10_RS07445	COG1487	ribonuclease activity
EBQ10_RS07530	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EBQ10_RS07560	COG1172	Belongs to the binding-protein-dependent transport system permease family
EBQ10_RS07565	COG1879	ABC-type sugar transport system periplasmic component
EBQ10_RS07570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBQ10_RS07600	COG0561	phosphatase activity
EBQ10_RS07605	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EBQ10_RS07615	COG0077	Prephenate dehydratase
EBQ10_RS07640	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EBQ10_RS07660	COG4868	Belongs to the UPF0371 family
EBQ10_RS07665	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EBQ10_RS07720	COG0521	Mo-molybdopterin cofactor biosynthetic process
EBQ10_RS07730	COG0315	cyclic pyranopterin monophosphate synthase activity
EBQ10_RS07740	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EBQ10_RS07765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EBQ10_RS07795	COG0596	Alpha beta hydrolase
EBQ10_RS07850	COG3655	Transcriptional regulator
EBQ10_RS07860	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EBQ10_RS07860	COG2890	protein-(glutamine-N5) methyltransferase activity
EBQ10_RS07865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EBQ10_RS07865	COG1754	DNA topoisomerase type I activity
EBQ10_RS07870	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EBQ10_RS07875	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EBQ10_RS07900	COG2801	Transposase and inactivated derivatives
EBQ10_RS07965	COG4824	toxin secretion phage lysis holin
EBQ10_RS08045	COG4695	Portal protein
EBQ10_RS08055	COG4626	Terminase
EBQ10_RS08055	COG1802	Transcriptional regulator
EBQ10_RS08085	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EBQ10_RS08130	COG3617	BRO family, N-terminal domain
EBQ10_RS08140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBQ10_RS08140	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EBQ10_RS08220	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EBQ10_RS08245	COG0717	Belongs to the dCTP deaminase family
EBQ10_RS08250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBQ10_RS08250	COG2111	Na H antiporter
EBQ10_RS08255	COG1006	Multisubunit Na H antiporter MnhC subunit
EBQ10_RS08260	COG0651	ATP synthesis coupled electron transport
EBQ10_RS08290	COG4149	molybdate abc transporter
EBQ10_RS08295	COG3842	ATPase activity
EBQ10_RS08310	COG0662	Cupin 2, conserved barrel domain protein
EBQ10_RS08335	COG1940	carbohydrate kinase activity
EBQ10_RS08340	COG0390	transport system, permease component
EBQ10_RS08350	COG1505	serine-type exopeptidase activity
EBQ10_RS08365	COG0243	molybdopterin cofactor binding
EBQ10_RS08370	COG1937	Protein conserved in bacteria
EBQ10_RS08375	COG0446	pyridine nucleotide-disulphide oxidoreductase
EBQ10_RS08385	COG0437	4 iron, 4 sulfur cluster binding
EBQ10_RS08390	COG0243	molybdopterin cofactor binding
EBQ10_RS08400	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EBQ10_RS08405	COG0540	Belongs to the ATCase OTCase family
EBQ10_RS08410	COG0284	orotidine-5'-phosphate decarboxylase activity
EBQ10_RS08415	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EBQ10_RS08425	COG0443	Heat shock 70 kDa protein
EBQ10_RS08430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EBQ10_RS08435	COG0484	heat shock protein binding
EBQ10_RS08460	COG0584	glycerophosphoryl diester phosphodiesterase
EBQ10_RS08465	COG1506	peptidase
EBQ10_RS08465	COG0823	Involved in the tonB-independent uptake of proteins
EBQ10_RS08475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EBQ10_RS08505	COG1028	Short-chain dehydrogenase reductase Sdr
EBQ10_RS08520	COG0494	nUDIX hydrolase
EBQ10_RS08535	COG0191	fructose-bisphosphate aldolase activity
EBQ10_RS08545	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EBQ10_RS08550	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EBQ10_RS08555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EBQ10_RS08560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EBQ10_RS08590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EBQ10_RS08620	COG0039	L-malate dehydrogenase activity
EBQ10_RS08625	COG0728	peptidoglycan biosynthetic process
EBQ10_RS08650	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EBQ10_RS08675	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EBQ10_RS08680	COG0406	alpha-ribazole phosphatase activity
EBQ10_RS08680	COG0494	nUDIX hydrolase
EBQ10_RS08700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EBQ10_RS08705	COG0306	phosphate transporter
EBQ10_RS08715	COG1115	amino acid carrier protein
EBQ10_RS08725	COG0737	Belongs to the 5'-nucleotidase family
EBQ10_RS08735	COG3485	protocatechuate 3,4-dioxygenase
EBQ10_RS08740	COG0354	folic acid binding
EBQ10_RS08750	COG1490	D-aminoacyl-tRNA deacylase activity
EBQ10_RS08770	COG0738	Major facilitator superfamily
EBQ10_RS08775	COG2390	Transcriptional regulator
EBQ10_RS08795	COG1349	DNA-binding transcription factor activity
EBQ10_RS08815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EBQ10_RS08820	COG2376	Dihydroxyacetone kinase
EBQ10_RS08830	COG0698	ribose 5-phosphate isomerase
EBQ10_RS08835	COG0730	response to heat
EBQ10_RS08840	COG0641	radical SAM
EBQ10_RS08845	COG2814	Major facilitator Superfamily
EBQ10_RS08850	COG1609	Transcriptional regulator
EBQ10_RS08855	COG3119	arylsulfatase activity
EBQ10_RS08875	COG3842	ATPase activity
EBQ10_RS08880	COG1940	carbohydrate kinase activity
EBQ10_RS08885	COG2115	Belongs to the xylose isomerase family
EBQ10_RS08890	COG1070	Carbohydrate kinase
EBQ10_RS08895	COG4213	ABC transporter substrate-binding protein
EBQ10_RS08905	COG4214	carbohydrate transport
EBQ10_RS08910	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EBQ10_RS08915	COG1757	Na H antiporter
EBQ10_RS08925	COG3250	beta-galactosidase activity
EBQ10_RS08935	COG0395	ABC-type sugar transport system, permease component
EBQ10_RS08945	COG1609	Transcriptional regulator
EBQ10_RS08955	COG0395	ABC-type sugar transport system, permease component
EBQ10_RS08960	COG1175	transmembrane transport
EBQ10_RS08975	COG3250	beta-galactosidase activity
EBQ10_RS08985	COG1609	Transcriptional regulator
EBQ10_RS08990	COG2610	gluconate transmembrane transporter activity
EBQ10_RS09010	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EBQ10_RS09015	COG3250	beta-galactosidase activity
EBQ10_RS09020	COG1869	D-ribose catabolic process
EBQ10_RS09025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBQ10_RS09030	COG1879	ABC-type sugar transport system periplasmic component
EBQ10_RS09035	COG1172	Belongs to the binding-protein-dependent transport system permease family
EBQ10_RS09040	COG1129	ABC transporter
EBQ10_RS09045	COG1609	Transcriptional regulator
EBQ10_RS09050	COG2226	methyltransferase
EBQ10_RS09055	COG1116	anion transmembrane transporter activity
EBQ10_RS09075	COG0737	Belongs to the 5'-nucleotidase family
EBQ10_RS09090	COG1609	Transcriptional regulator
EBQ10_RS09095	COG2271	Major facilitator Superfamily
EBQ10_RS09105	COG5564	TIM-barrel signal transduction protein
EBQ10_RS09115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBQ10_RS09135	COG1397	ADP-ribosylglycohydrolase
EBQ10_RS09140	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EBQ10_RS09145	COG1122	ATPase activity
EBQ10_RS09225	COG1518	maintenance of DNA repeat elements
EBQ10_RS09240	COG3609	addiction module antidote protein, CC2985 family
EBQ10_RS09255	COG0366	Alpha amylase catalytic
EBQ10_RS09260	COG0395	ABC-type sugar transport system, permease component
EBQ10_RS09265	COG1175	transmembrane transport
EBQ10_RS09280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBQ10_RS09280	COG0574	Belongs to the PEP-utilizing enzyme family
EBQ10_RS09285	COG0247	lactate metabolic process
EBQ10_RS09285	COG0277	FAD linked oxidase domain protein
EBQ10_RS09295	COG2267	carboxylic ester hydrolase activity
EBQ10_RS09300	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EBQ10_RS09305	COG0791	NLP P60 protein
EBQ10_RS09310	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EBQ10_RS09325	COG0037	tRNA processing
EBQ10_RS09335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EBQ10_RS09340	COG0302	gtp cyclohydrolase
EBQ10_RS09370	COG1609	Transcriptional regulator
EBQ10_RS09390	COG3250	beta-galactosidase activity
EBQ10_RS09400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EBQ10_RS09400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EBQ10_RS09405	COG1461	Dihydroxyacetone kinase
EBQ10_RS09410	COG2376	Dihydroxyacetone kinase
EBQ10_RS09420	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EBQ10_RS09425	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EBQ10_RS09435	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EBQ10_RS09440	COG2409	Drug exporters of the RND superfamily
EBQ10_RS09445	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EBQ10_RS09450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EBQ10_RS09460	COG3386	PFAM SMP-30 Gluconolaconase
EBQ10_RS09465	COG0247	lactate metabolic process
EBQ10_RS09470	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
EBQ10_RS09475	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EBQ10_RS09490	COG1194	a g-specific adenine glycosylase
EBQ10_RS09500	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EBQ10_RS09505	COG0569	domain protein
EBQ10_RS09510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EBQ10_RS09525	COG1846	Transcriptional regulator
EBQ10_RS09530	COG0406	alpha-ribazole phosphatase activity
EBQ10_RS09555	COG0395	ABC-type sugar transport system, permease component
EBQ10_RS09560	COG1175	transmembrane transport
EBQ10_RS09570	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EBQ10_RS09575	COG4948	Mandelate Racemase Muconate Lactonizing
EBQ10_RS09580	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EBQ10_RS09585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EBQ10_RS09590	COG1169	isochorismate synthase
EBQ10_RS09595	COG2226	methyltransferase
EBQ10_RS09600	COG0644	oxidoreductase
EBQ10_RS09610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBQ10_RS09615	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBQ10_RS09620	COG0649	NAD binding
EBQ10_RS09630	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EBQ10_RS09635	COG1034	ATP synthesis coupled electron transport
EBQ10_RS09640	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EBQ10_RS09645	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EBQ10_RS09650	COG0839	Belongs to the complex I subunit 6 family
EBQ10_RS09655	COG0713	ATP synthesis coupled electron transport
EBQ10_RS09660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EBQ10_RS09670	COG1007	ATP synthesis coupled electron transport
EBQ10_RS09675	COG0142	geranyltranstransferase activity
EBQ10_RS09680	COG0653	protein targeting
EBQ10_RS09720	COG0419	ATPase involved in DNA repair
EBQ10_RS09725	COG0420	3'-5' exonuclease activity
EBQ10_RS09730	COG0483	inositol monophosphate 1-phosphatase activity
EBQ10_RS09735	COG1162	GTPase activity
EBQ10_RS09740	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EBQ10_RS09760	COG0657	acetylesterase activity
EBQ10_RS09775	COG0601	transmembrane transport
EBQ10_RS09780	COG0444	Belongs to the ABC transporter superfamily
EBQ10_RS09785	COG4608	Belongs to the ABC transporter superfamily
EBQ10_RS09790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EBQ10_RS09800	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EBQ10_RS09805	COG0363	glucosamine-6-phosphate deaminase activity
EBQ10_RS09815	COG1595	DNA-templated transcription, initiation
EBQ10_RS09830	COG3103	Sh3 type 3 domain protein
EBQ10_RS09830	COG0791	NLP P60 protein
EBQ10_RS09830	COG1388	LysM domain
EBQ10_RS09840	COG0508	dehydrogenase complex catalyzes the overall conversion of
EBQ10_RS09840	COG0567	Dehydrogenase, E1 component
EBQ10_RS09845	COG1253	flavin adenine dinucleotide binding
EBQ10_RS09855	COG0739	heme binding
EBQ10_RS09860	COG0584	glycerophosphoryl diester phosphodiesterase
EBQ10_RS09875	COG1136	(ABC) transporter
EBQ10_RS09900	COG0018	arginyl-trna synthetase
EBQ10_RS09910	COG0460	homoserine dehydrogenase
EBQ10_RS09915	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EBQ10_RS09920	COG0083	homoserine kinase activity
EBQ10_RS09935	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EBQ10_RS09960	COG0356	it plays a direct role in the translocation of protons across the membrane
EBQ10_RS09965	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EBQ10_RS09970	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EBQ10_RS09975	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EBQ10_RS09980	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EBQ10_RS09985	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EBQ10_RS09990	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EBQ10_RS09995	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EBQ10_RS10005	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EBQ10_RS10050	COG1609	Transcriptional regulator
EBQ10_RS10060	COG1175	transmembrane transport
EBQ10_RS10065	COG3833	ABC-type maltose transport systems, permease component
EBQ10_RS10080	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EBQ10_RS10085	COG3281	Trehalose synthase
EBQ10_RS10090	COG0366	Alpha amylase catalytic
EBQ10_RS10095	COG0366	Alpha amylase catalytic
EBQ10_RS10120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EBQ10_RS10125	COG0058	SHG alpha-glucan phosphorylase activity
EBQ10_RS10130	COG0180	Tryptophanyl-tRNA synthetase
EBQ10_RS10160	COG3480	Lon protease (S16) C-terminal proteolytic domain
EBQ10_RS10170	COG1615	UPF0182 protein
EBQ10_RS10175	COG1470	cell adhesion involved in biofilm formation
EBQ10_RS10175	COG0366	Alpha amylase catalytic
EBQ10_RS10195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EBQ10_RS10200	COG1131	(ABC) transporter
EBQ10_RS10210	COG0387	Pfam Sodium calcium exchanger
EBQ10_RS10220	COG1053	succinate dehydrogenase
EBQ10_RS10245	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EBQ10_RS10280	COG4585	Histidine kinase
EBQ10_RS10285	COG2135	peptidase activity
EBQ10_RS10290	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EBQ10_RS10300	COG1397	ADP-ribosylglycohydrolase
EBQ10_RS10310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EBQ10_RS10325	COG1404	Belongs to the peptidase S8 family
EBQ10_RS10330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EBQ10_RS10335	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EBQ10_RS10340	COG0154	amidase activity
EBQ10_RS10345	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EBQ10_RS10395	COG0129	dihydroxy-acid dehydratase activity
EBQ10_RS10400	COG2985	domain, Protein
EBQ10_RS10400	COG0569	domain protein
EBQ10_RS10410	COG0440	acetolactate synthase activity
EBQ10_RS10415	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EBQ10_RS10430	COG1027	Aspartate ammonia-lyase
EBQ10_RS10445	COG0473	3-isopropylmalate dehydrogenase activity
EBQ10_RS10450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EBQ10_RS10460	COG1882	Formate acetyltransferase
EBQ10_RS10490	COG0438	transferase activity, transferring glycosyl groups
EBQ10_RS10495	COG4750	Nucleotidyl transferase
EBQ10_RS10500	COG3475	LICD family
EBQ10_RS10505	COG1216	Glycosyl transferase, family 2
EBQ10_RS10505	COG1442	glycosyl transferase family 8
EBQ10_RS10530	COG2244	polysaccharide biosynthetic process
EBQ10_RS10535	COG0463	Glycosyl transferase, family 2
EBQ10_RS10570	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EBQ10_RS10600	COG1946	Acyl-CoA thioesterase
EBQ10_RS10615	COG0519	Catalyzes the synthesis of GMP from XMP
EBQ10_RS10625	COG2354	Protein conserved in bacteria
EBQ10_RS10630	COG3590	peptidase
EBQ10_RS10645	COG1045	serine acetyltransferase
EBQ10_RS10655	COG1739	Uncharacterized protein family UPF0029
EBQ10_RS10670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EBQ10_RS10685	COG0488	(ABC) transporter
EBQ10_RS10700	COG1609	Transcriptional regulator
EBQ10_RS10705	COG3250	beta-galactosidase activity
EBQ10_RS10725	COG0667	Aldo Keto reductase
EBQ10_RS10730	COG0544	peptidyl-prolyl cis-trans isomerase activity
EBQ10_RS10735	COG0740	serine-type endopeptidase activity
EBQ10_RS10740	COG0740	serine-type endopeptidase activity
EBQ10_RS10745	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EBQ10_RS10750	COG0287	Prephenate dehydrogenase
EBQ10_RS10750	COG1605	Chorismate mutase
EBQ10_RS10770	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EBQ10_RS10785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EBQ10_RS10790	COG0285	dihydrofolate synthase activity
EBQ10_RS10795	COG0105	UTP biosynthetic process
EBQ10_RS10835	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EBQ10_RS10840	COG0228	four-way junction DNA binding
EBQ10_RS10845	COG1837	Belongs to the UPF0109 family
EBQ10_RS10850	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EBQ10_RS10860	COG0335	large ribosomal subunit rRNA binding
EBQ10_RS10865	COG0681	Belongs to the peptidase S26 family
EBQ10_RS10870	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EBQ10_RS10895	COG4974	Belongs to the 'phage' integrase family
EBQ10_RS10900	COG1388	LysM domain
EBQ10_RS10900	COG4942	peptidase
EBQ10_RS10905	COG2860	membrane
EBQ10_RS10910	COG0052	Belongs to the universal ribosomal protein uS2 family
EBQ10_RS10915	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EBQ10_RS10925	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
EBQ10_RS10930	COG0644	oxidoreductase
EBQ10_RS10955	COG0233	cytoplasmic translational termination