locus-tag	class	description
HEP79_RS00020	COG1518	maintenance of DNA repeat elements
HEP79_RS00035	COG3609	addiction module antidote protein, CC2985 family
HEP79_RS00050	COG0366	Alpha amylase catalytic
HEP79_RS00055	COG0395	ABC-type sugar transport system, permease component
HEP79_RS00060	COG1175	transmembrane transport
HEP79_RS00075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEP79_RS00075	COG0574	Belongs to the PEP-utilizing enzyme family
HEP79_RS00080	COG0277	FAD linked oxidase domain protein
HEP79_RS00080	COG0247	lactate metabolic process
HEP79_RS00090	COG2267	carboxylic ester hydrolase activity
HEP79_RS00095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HEP79_RS00100	COG0791	NLP P60 protein
HEP79_RS00105	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HEP79_RS00120	COG0037	tRNA processing
HEP79_RS00130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEP79_RS00135	COG0302	gtp cyclohydrolase
HEP79_RS00165	COG1609	Transcriptional regulator
HEP79_RS00185	COG3250	beta-galactosidase activity
HEP79_RS00195	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEP79_RS00195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEP79_RS00200	COG1461	Dihydroxyacetone kinase
HEP79_RS00205	COG2376	Dihydroxyacetone kinase
HEP79_RS00215	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HEP79_RS00220	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HEP79_RS00230	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HEP79_RS00235	COG2409	Drug exporters of the RND superfamily
HEP79_RS00240	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEP79_RS00245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HEP79_RS00255	COG3386	PFAM SMP-30 Gluconolaconase
HEP79_RS00260	COG0247	lactate metabolic process
HEP79_RS00265	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
HEP79_RS00270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEP79_RS00285	COG1194	a g-specific adenine glycosylase
HEP79_RS00295	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEP79_RS00300	COG0569	domain protein
HEP79_RS00305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HEP79_RS00320	COG1846	Transcriptional regulator
HEP79_RS00325	COG0406	alpha-ribazole phosphatase activity
HEP79_RS00350	COG0395	ABC-type sugar transport system, permease component
HEP79_RS00355	COG1175	transmembrane transport
HEP79_RS00365	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEP79_RS00370	COG4948	Mandelate Racemase Muconate Lactonizing
HEP79_RS00375	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HEP79_RS00385	COG1169	isochorismate synthase
HEP79_RS00390	COG2226	methyltransferase
HEP79_RS00395	COG0644	oxidoreductase
HEP79_RS00405	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HEP79_RS00410	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HEP79_RS00415	COG0649	NAD binding
HEP79_RS00425	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HEP79_RS00430	COG1034	ATP synthesis coupled electron transport
HEP79_RS00435	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HEP79_RS00440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HEP79_RS00445	COG0839	Belongs to the complex I subunit 6 family
HEP79_RS00450	COG0713	ATP synthesis coupled electron transport
HEP79_RS00465	COG1007	ATP synthesis coupled electron transport
HEP79_RS00475	COG0653	protein targeting
HEP79_RS00515	COG0419	ATPase involved in DNA repair
HEP79_RS00520	COG0420	3'-5' exonuclease activity
HEP79_RS00525	COG0483	inositol monophosphate 1-phosphatase activity
HEP79_RS00530	COG1162	GTPase activity
HEP79_RS00535	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HEP79_RS00575	COG0444	Belongs to the ABC transporter superfamily
HEP79_RS00580	COG4608	Belongs to the ABC transporter superfamily
HEP79_RS00585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEP79_RS00595	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HEP79_RS00600	COG0363	glucosamine-6-phosphate deaminase activity
HEP79_RS00610	COG1595	DNA-templated transcription, initiation
HEP79_RS00620	COG1388	LysM domain
HEP79_RS00620	COG3103	Sh3 type 3 domain protein
HEP79_RS00620	COG0791	NLP P60 protein
HEP79_RS00630	COG0508	dehydrogenase complex catalyzes the overall conversion of
HEP79_RS00630	COG0567	Dehydrogenase, E1 component
HEP79_RS00635	COG1253	flavin adenine dinucleotide binding
HEP79_RS00645	COG0739	heme binding
HEP79_RS00650	COG0584	glycerophosphoryl diester phosphodiesterase
HEP79_RS00680	COG0018	arginyl-trna synthetase
HEP79_RS00690	COG0460	homoserine dehydrogenase
HEP79_RS00695	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HEP79_RS00700	COG0083	homoserine kinase activity
HEP79_RS00715	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEP79_RS00740	COG0356	it plays a direct role in the translocation of protons across the membrane
HEP79_RS00745	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEP79_RS00750	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEP79_RS00755	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEP79_RS00760	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEP79_RS00765	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEP79_RS00770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEP79_RS00775	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HEP79_RS00785	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HEP79_RS00830	COG1609	Transcriptional regulator
HEP79_RS00840	COG1175	transmembrane transport
HEP79_RS00845	COG3833	ABC-type maltose transport systems, permease component
HEP79_RS00860	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HEP79_RS00865	COG3281	Trehalose synthase
HEP79_RS00870	COG0366	Alpha amylase catalytic
HEP79_RS00875	COG0366	Alpha amylase catalytic
HEP79_RS00900	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HEP79_RS00905	COG0058	SHG alpha-glucan phosphorylase activity
HEP79_RS00910	COG0180	Tryptophanyl-tRNA synthetase
HEP79_RS00940	COG3480	Lon protease (S16) C-terminal proteolytic domain
HEP79_RS00950	COG1615	UPF0182 protein
HEP79_RS00955	COG1470	cell adhesion involved in biofilm formation
HEP79_RS00955	COG0366	Alpha amylase catalytic
HEP79_RS00975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HEP79_RS00980	COG1131	(ABC) transporter
HEP79_RS00990	COG0387	Pfam Sodium calcium exchanger
HEP79_RS01000	COG1053	succinate dehydrogenase
HEP79_RS01025	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEP79_RS01060	COG4585	Histidine kinase
HEP79_RS01065	COG2135	peptidase activity
HEP79_RS01070	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEP79_RS01080	COG1397	ADP-ribosylglycohydrolase
HEP79_RS01090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEP79_RS01105	COG1404	Belongs to the peptidase S8 family
HEP79_RS01110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEP79_RS01115	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEP79_RS01120	COG0154	amidase activity
HEP79_RS01125	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEP79_RS01175	COG0129	dihydroxy-acid dehydratase activity
HEP79_RS01180	COG2985	domain, Protein
HEP79_RS01180	COG0569	domain protein
HEP79_RS01190	COG0440	acetolactate synthase activity
HEP79_RS01195	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEP79_RS01205	COG1027	Aspartate ammonia-lyase
HEP79_RS01220	COG0473	3-isopropylmalate dehydrogenase activity
HEP79_RS01225	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HEP79_RS01235	COG1882	Formate acetyltransferase
HEP79_RS01265	COG0438	transferase activity, transferring glycosyl groups
HEP79_RS01270	COG4750	Nucleotidyl transferase
HEP79_RS01275	COG3475	LICD family
HEP79_RS01280	COG1442	glycosyl transferase family 8
HEP79_RS01280	COG1216	Glycosyl transferase, family 2
HEP79_RS01295	COG0463	Glycosyl transferase, family 2
HEP79_RS01305	COG2244	polysaccharide biosynthetic process
HEP79_RS01310	COG0463	Glycosyl transferase, family 2
HEP79_RS01340	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HEP79_RS01370	COG1946	Acyl-CoA thioesterase
HEP79_RS01385	COG0519	Catalyzes the synthesis of GMP from XMP
HEP79_RS01395	COG2354	Protein conserved in bacteria
HEP79_RS01400	COG3590	peptidase
HEP79_RS01415	COG1045	serine acetyltransferase
HEP79_RS01425	COG1739	Uncharacterized protein family UPF0029
HEP79_RS01440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HEP79_RS01455	COG0488	(ABC) transporter
HEP79_RS01470	COG1609	Transcriptional regulator
HEP79_RS01475	COG3250	beta-galactosidase activity
HEP79_RS01495	COG0667	Aldo Keto reductase
HEP79_RS01500	COG0544	peptidyl-prolyl cis-trans isomerase activity
HEP79_RS01505	COG0740	serine-type endopeptidase activity
HEP79_RS01510	COG0740	serine-type endopeptidase activity
HEP79_RS01515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEP79_RS01520	COG0287	Prephenate dehydrogenase
HEP79_RS01520	COG1605	Chorismate mutase
HEP79_RS01540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEP79_RS01555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEP79_RS01560	COG0285	dihydrofolate synthase activity
HEP79_RS01565	COG0105	UTP biosynthetic process
HEP79_RS01605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEP79_RS01615	COG1837	Belongs to the UPF0109 family
HEP79_RS01620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEP79_RS01630	COG0335	large ribosomal subunit rRNA binding
HEP79_RS01635	COG0681	Belongs to the peptidase S26 family
HEP79_RS01640	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEP79_RS01665	COG4974	Belongs to the 'phage' integrase family
HEP79_RS01670	COG1388	LysM domain
HEP79_RS01670	COG4942	peptidase
HEP79_RS01675	COG2860	membrane
HEP79_RS01680	COG0052	Belongs to the universal ribosomal protein uS2 family
HEP79_RS01685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEP79_RS01695	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HEP79_RS01700	COG0644	oxidoreductase
HEP79_RS01725	COG0233	cytoplasmic translational termination
HEP79_RS01735	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HEP79_RS01745	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HEP79_RS01750	COG0750	zinc metalloprotease
HEP79_RS01755	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HEP79_RS01765	COG0442	prolyl-tRNA aminoacylation
HEP79_RS01775	COG0779	Required for maturation of 30S ribosomal subunits
HEP79_RS01790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEP79_RS01795	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEP79_RS01800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEP79_RS01805	COG3852	Histidine kinase
HEP79_RS01810	COG0745	RESPONSE REGULATOR receiver
HEP79_RS01815	COG2271	Major facilitator Superfamily
HEP79_RS01825	COG3842	ATPase activity
HEP79_RS01855	COG1129	ABC transporter
HEP79_RS01855	COG0842	Transport permease protein
HEP79_RS01870	COG1185	polyribonucleotide nucleotidyltransferase activity
HEP79_RS01880	COG0612	Peptidase, M16
HEP79_RS01885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HEP79_RS01890	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HEP79_RS01905	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEP79_RS01910	COG1674	ftsk spoiiie
HEP79_RS01925	COG1058	Belongs to the CinA family
HEP79_RS01925	COG1546	Belongs to the CinA family
HEP79_RS01930	COG1396	sequence-specific DNA binding
HEP79_RS01940	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEP79_RS01945	COG2137	regulation of response to DNA damage stimulus
HEP79_RS01950	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEP79_RS01955	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEP79_RS01965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEP79_RS01975	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEP79_RS01985	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEP79_RS01990	COG0318	PFAM AMP-dependent synthetase and ligase
HEP79_RS01995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HEP79_RS02015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEP79_RS02025	COG2001	Belongs to the MraZ family
HEP79_RS02030	COG0275	rRNA processing
HEP79_RS02040	COG0768	penicillin binding
HEP79_RS02045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEP79_RS02050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HEP79_RS02055	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEP79_RS02060	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEP79_RS02070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEP79_RS02075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HEP79_RS02085	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEP79_RS02095	COG1799	cell septum assembly
HEP79_RS02110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEP79_RS02125	COG0587	DNA-directed DNA polymerase activity
HEP79_RS02140	COG0735	belongs to the Fur family
HEP79_RS02145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HEP79_RS02150	COG1121	(ABC) transporter
HEP79_RS02160	COG0423	glycine-tRNA ligase activity
HEP79_RS02185	COG0358	DNA primase activity
HEP79_RS02195	COG0805	protein transport
HEP79_RS02200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEP79_RS02235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEP79_RS02240	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HEP79_RS02275	COG1090	epimerase
HEP79_RS02295	COG0009	L-threonylcarbamoyladenylate synthase
HEP79_RS02315	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HEP79_RS02340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEP79_RS02345	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEP79_RS02350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEP79_RS02360	COG3022	response to hydroperoxide
HEP79_RS02370	COG1940	carbohydrate kinase activity
HEP79_RS02385	COG0174	glutamine synthetase
HEP79_RS02390	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HEP79_RS02400	COG0174	glutamine synthetase
HEP79_RS02420	COG0508	dehydrogenase complex catalyzes the overall conversion of
HEP79_RS02425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HEP79_RS02435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HEP79_RS02450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HEP79_RS02490	COG0205	6-phosphofructokinase activity
HEP79_RS02495	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HEP79_RS02500	COG2815	serine threonine protein kinase
HEP79_RS02500	COG0515	serine threonine protein kinase
HEP79_RS02530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEP79_RS02535	COG1199	ATP-dependent helicase activity
HEP79_RS02535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HEP79_RS02540	COG0187	DNA topoisomerase II activity
HEP79_RS02555	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEP79_RS02595	COG0569	domain protein
HEP79_RS02610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HEP79_RS02620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEP79_RS02685	COG2197	response regulator
HEP79_RS02690	COG1760	l-serine dehydratase
HEP79_RS02695	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEP79_RS02700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEP79_RS02710	COG0438	transferase activity, transferring glycosyl groups
HEP79_RS02720	COG1051	belongs to the nudix hydrolase family
HEP79_RS02725	COG0217	transcriptional regulatory protein
HEP79_RS02730	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HEP79_RS02735	COG0632	four-way junction helicase activity
HEP79_RS02740	COG2255	four-way junction helicase activity
HEP79_RS02750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEP79_RS02755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEP79_RS02760	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEP79_RS02765	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEP79_RS02775	COG1196	nuclear chromosome segregation
HEP79_RS02780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HEP79_RS02785	COG0124	histidyl-tRNA synthetase
HEP79_RS02790	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEP79_RS02795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEP79_RS02815	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HEP79_RS02830	COG2409	Drug exporters of the RND superfamily
HEP79_RS02840	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEP79_RS02850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEP79_RS02855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEP79_RS02875	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEP79_RS02885	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEP79_RS02890	COG2217	Heavy metal translocating P-type atpase
HEP79_RS02895	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEP79_RS02900	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEP79_RS02920	COG0194	GDP metabolic process
HEP79_RS02925	COG1758	RNA polymerase activity
HEP79_RS02935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEP79_RS02940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEP79_RS02945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEP79_RS02955	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HEP79_RS02960	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HEP79_RS02965	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HEP79_RS02970	COG0140	phosphoribosyl-ATP diphosphatase activity
HEP79_RS02975	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HEP79_RS03005	COG4581	dead DEAH box helicase
HEP79_RS03015	COG1216	Glycosyl transferase, family 2
HEP79_RS03060	COG0205	6-phosphofructokinase activity
HEP79_RS03065	COG1160	GTP binding
HEP79_RS03080	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEP79_RS03105	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HEP79_RS03120	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HEP79_RS03125	COG0149	triose-phosphate isomerase activity
HEP79_RS03130	COG0126	phosphoglycerate kinase activity
HEP79_RS03135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HEP79_RS03140	COG1481	regulation of sporulation
HEP79_RS03150	COG1660	Displays ATPase and GTPase activities
HEP79_RS03155	COG0322	excinuclease ABC activity
HEP79_RS03180	COG0556	nucleotide-excision repair
HEP79_RS03185	COG0237	dephospho-CoA kinase activity
HEP79_RS03190	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HEP79_RS03195	COG1136	(ABC) transporter
HEP79_RS03205	COG0539	negative regulation of cytoplasmic translation
HEP79_RS03230	COG0469	pyruvate kinase activity
HEP79_RS03235	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEP79_RS03240	COG0134	indole-3-glycerol-phosphate synthase activity
HEP79_RS03250	COG0107	imidazoleglycerol-phosphate synthase activity
HEP79_RS03265	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HEP79_RS03275	COG4122	O-methyltransferase activity
HEP79_RS03280	COG1222	aaa ATPase
HEP79_RS03300	COG1968	undecaprenyl-diphosphatase activity
HEP79_RS03315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HEP79_RS03325	COG0519	Catalyzes the synthesis of GMP from XMP
HEP79_RS03325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HEP79_RS03350	COG0587	DNA-directed DNA polymerase activity
HEP79_RS03365	COG1881	PFAM PEBP family protein
HEP79_RS03400	COG1119	ATPase activity
HEP79_RS03405	COG0297	glycogen (starch) synthase activity
HEP79_RS03415	COG1136	(ABC) transporter
HEP79_RS03425	COG3830	Belongs to the UPF0237 family
HEP79_RS03425	COG0560	Phosphoserine phosphatase
HEP79_RS03435	COG0488	(ABC) transporter
HEP79_RS03440	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEP79_RS03445	COG2151	metal-sulfur cluster biosynthetic enzyme
HEP79_RS03460	COG0396	ATPase activity
HEP79_RS03490	COG0728	peptidoglycan biosynthetic process
HEP79_RS03510	COG0497	DNA recombination
HEP79_RS03515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEP79_RS03530	COG0647	UMP catabolic process
HEP79_RS03560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HEP79_RS03565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HEP79_RS03570	COG1121	(ABC) transporter
HEP79_RS03575	COG0803	Belongs to the bacterial solute-binding protein 9 family
HEP79_RS03580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEP79_RS03585	COG1131	(ABC) transporter
HEP79_RS03595	COG1476	TRANSCRIPTIONal
HEP79_RS03605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HEP79_RS03610	COG1438	arginine binding
HEP79_RS03625	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HEP79_RS03630	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEP79_RS03650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEP79_RS03665	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HEP79_RS03670	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEP79_RS03680	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEP79_RS03685	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEP79_RS03695	COG0131	Imidazoleglycerol-phosphate dehydratase
HEP79_RS03705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEP79_RS03710	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEP79_RS03715	COG1381	Involved in DNA repair and RecF pathway recombination
HEP79_RS03720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEP79_RS03755	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEP79_RS03765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HEP79_RS03770	COG0484	heat shock protein binding
HEP79_RS03775	COG1420	regulation of RNA biosynthetic process
HEP79_RS03795	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HEP79_RS03800	COG0481	GTPase activity
HEP79_RS03825	COG0268	Binds directly to 16S ribosomal RNA
HEP79_RS03830	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HEP79_RS03835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HEP79_RS03855	COG0433	COG0433 Predicted ATPase
HEP79_RS03870	COG0495	leucyl-tRNA aminoacylation
HEP79_RS03895	COG0813	purine-nucleoside phosphorylase activity
HEP79_RS03905	COG1435	thymidine kinase activity
HEP79_RS03925	COG0803	Belongs to the bacterial solute-binding protein 9 family
HEP79_RS03935	COG1121	(ABC) transporter
HEP79_RS03940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HEP79_RS03960	COG0671	phosphoesterase, PA-phosphatase related
HEP79_RS03970	COG1395	domain, Protein
HEP79_RS03980	COG1113	amino acid transport
HEP79_RS03985	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HEP79_RS03985	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HEP79_RS03995	COG2011	ABC-type metal ion transport system permease component
HEP79_RS04000	COG1464	Belongs to the NlpA lipoprotein family
HEP79_RS04005	COG1113	amino acid transport
HEP79_RS04015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HEP79_RS04035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HEP79_RS04080	COG0726	polysaccharide deacetylase
HEP79_RS04085	COG0133	tryptophan synthase activity
HEP79_RS04090	COG1609	Transcriptional regulator
HEP79_RS04100	COG0738	Major facilitator superfamily
HEP79_RS04105	COG0235	Class ii aldolase
HEP79_RS04140	COG0406	alpha-ribazole phosphatase activity
HEP79_RS04145	COG0799	negative regulation of ribosome biogenesis
HEP79_RS04155	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEP79_RS04160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HEP79_RS04170	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEP79_RS04180	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HEP79_RS04185	COG1530	ribonuclease E activity
HEP79_RS04190	COG1271	oxidase subunit
HEP79_RS04195	COG1294	oxidase, subunit
HEP79_RS04200	COG4988	ABC transporter
HEP79_RS04205	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HEP79_RS04215	COG1132	(ABC) transporter
HEP79_RS04220	COG1132	(ABC) transporter
HEP79_RS04240	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HEP79_RS04245	COG0571	ribonuclease III activity
HEP79_RS04260	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEP79_RS04275	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HEP79_RS04285	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HEP79_RS04295	COG1181	Belongs to the D-alanine--D-alanine ligase family
HEP79_RS04300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEP79_RS04320	COG0438	transferase activity, transferring glycosyl groups
HEP79_RS04330	COG4975	Glucose uptake
HEP79_RS04335	COG0339	signal peptide processing
HEP79_RS04395	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HEP79_RS04400	COG0179	Fumarylacetoacetate (FAA) hydrolase
HEP79_RS04405	COG1022	Amp-dependent synthetase and ligase
HEP79_RS04430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEP79_RS04435	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HEP79_RS04445	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HEP79_RS04455	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HEP79_RS04480	COG0569	domain protein
HEP79_RS04480	COG2985	domain, Protein
HEP79_RS04495	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HEP79_RS04570	COG1846	Transcriptional regulator
HEP79_RS04575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HEP79_RS04605	COG1619	proteins homologs of microcin C7 resistance protein MccF
HEP79_RS04620	COG0739	heme binding
HEP79_RS04625	COG2177	Part of the ABC transporter FtsEX involved in
HEP79_RS04630	COG2884	Cell division ATP-binding protein ftsE
HEP79_RS04635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEP79_RS04695	COG0513	Belongs to the DEAD box helicase family
HEP79_RS04700	COG2095	MarC family integral membrane protein
HEP79_RS04710	COG0006	proline dipeptidase activity
HEP79_RS04715	COG2239	Acts as a magnesium transporter
HEP79_RS04740	COG1611	Belongs to the LOG family
HEP79_RS04750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEP79_RS04755	COG1309	transcriptional regulator
HEP79_RS04760	COG2814	Major facilitator Superfamily
HEP79_RS04765	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEP79_RS04805	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HEP79_RS04805	COG0662	Cupin 2, conserved barrel domain protein
HEP79_RS04820	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEP79_RS04825	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEP79_RS04835	COG1268	BioY protein
HEP79_RS04845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HEP79_RS04850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HEP79_RS04855	COG4770	biotin carboxylase activity
HEP79_RS04875	COG0644	oxidoreductase
HEP79_RS04880	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HEP79_RS04895	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HEP79_RS04900	COG2271	Major facilitator Superfamily
HEP79_RS04905	COG2030	dehydratase
HEP79_RS04945	COG0039	L-malate dehydrogenase activity
HEP79_RS04960	COG2826	transposase and inactivated derivatives, IS30 family
HEP79_RS04965	COG2826	transposase and inactivated derivatives, IS30 family
HEP79_RS05010	COG0166	Belongs to the GPI family
HEP79_RS05015	COG0205	6-phosphofructokinase activity
HEP79_RS05045	COG0045	succinate-CoA ligase (ADP-forming) activity
HEP79_RS05050	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HEP79_RS05050	COG2755	lipolytic protein G-D-S-L family
HEP79_RS05065	COG0653	protein targeting
HEP79_RS05115	COG0095	Lipoate-protein ligase
HEP79_RS05145	COG1484	DNA-dependent DNA replication
HEP79_RS05390	COG0857	belongs to the CobB CobQ family
HEP79_RS05390	COG0280	phosphate acetyltransferase
HEP79_RS05460	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEP79_RS05465	COG0151	Belongs to the GarS family
HEP79_RS05470	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEP79_RS05475	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HEP79_RS05480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEP79_RS05485	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HEP79_RS05490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEP79_RS05500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEP79_RS05510	COG0428	transporter
HEP79_RS05515	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEP79_RS05520	COG0733	neurotransmitter:sodium symporter activity
HEP79_RS05530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HEP79_RS05535	COG1053	succinate dehydrogenase
HEP79_RS05560	COG0802	atpase or kinase
HEP79_RS05565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEP79_RS05575	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HEP79_RS05580	COG1072	(Pantothenic acid kinase))
HEP79_RS05590	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HEP79_RS05595	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEP79_RS05605	COG4720	Psort location CytoplasmicMembrane, score
HEP79_RS05610	COG1122	ATPase activity
HEP79_RS05630	COG0101	tRNA pseudouridine synthase activity
HEP79_RS05635	COG1940	carbohydrate kinase activity
HEP79_RS05645	COG0765	amino acid transport
HEP79_RS05650	COG1126	abc transporter atp-binding protein
HEP79_RS05655	COG0789	Transcriptional regulator
HEP79_RS05660	COG1666	GTP binding
HEP79_RS05665	COG0203	ribosomal protein L17
HEP79_RS05670	COG0202	RNA polymerase activity
HEP79_RS05680	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEP79_RS05685	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HEP79_RS05690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEP79_RS05700	COG0563	adenylate kinase activity
HEP79_RS05710	COG0200	Binds to the 23S rRNA
HEP79_RS05715	COG1841	ribosomal large subunit assembly
HEP79_RS05720	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEP79_RS05730	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEP79_RS05735	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEP79_RS05740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEP79_RS05745	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEP79_RS05750	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEP79_RS05755	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEP79_RS05770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEP79_RS05775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEP79_RS05780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEP79_RS05785	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEP79_RS05790	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEP79_RS05795	COG0089	rRNA binding
HEP79_RS05800	COG0088	Forms part of the polypeptide exit tunnel
HEP79_RS05805	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEP79_RS05810	COG0051	transcription antitermination factor activity, RNA binding
HEP79_RS05815	COG0546	phosphoglycolate phosphatase activity
HEP79_RS05825	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEP79_RS05830	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEP79_RS05835	COG0049	tRNA binding
HEP79_RS05840	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEP79_RS05845	COG0833	amino acid
HEP79_RS05850	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEP79_RS05855	COG0085	RNA polymerase activity
HEP79_RS05860	COG0222	ribosome binding
HEP79_RS05865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEP79_RS05875	COG0081	regulation of translation
HEP79_RS05880	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEP79_RS05885	COG0250	Participates in transcription elongation, termination and antitermination
HEP79_RS05900	COG0436	Aminotransferase
HEP79_RS05910	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HEP79_RS05925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HEP79_RS05935	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HEP79_RS05955	COG1666	GTP binding
HEP79_RS05965	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEP79_RS05970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEP79_RS05975	COG5401	PFAM Sporulation and spore germination
HEP79_RS05980	COG5002	protein histidine kinase activity
HEP79_RS05980	COG5000	phosphorelay sensor kinase activity
HEP79_RS05985	COG0745	RESPONSE REGULATOR receiver
HEP79_RS06005	COG0714	Associated with various cellular activities
HEP79_RS06050	COG0483	inositol monophosphate 1-phosphatase activity
HEP79_RS06065	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEP79_RS06160	COG0673	inositol 2-dehydrogenase activity
HEP79_RS06185	COG1088	dTDP-glucose 4,6-dehydratase activity
HEP79_RS06200	COG1316	TRANSCRIPTIONal
HEP79_RS06205	COG1316	TRANSCRIPTIONal
HEP79_RS06215	COG0642	Histidine kinase
HEP79_RS06220	COG0745	RESPONSE REGULATOR receiver
HEP79_RS06235	COG0424	maF-like protein
HEP79_RS06280	COG1132	(ABC) transporter
HEP79_RS06310	COG0321	lipoyl(octanoyl) transferase activity
HEP79_RS06315	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HEP79_RS06325	COG1362	aminopeptidase activity
HEP79_RS06340	COG2838	Isocitrate dehydrogenase
HEP79_RS06345	COG2391	methyltransferase activity
HEP79_RS06350	COG0425	Belongs to the sulfur carrier protein TusA family
HEP79_RS06355	COG0366	Alpha amylase catalytic
HEP79_RS06360	COG1501	Belongs to the glycosyl hydrolase 31 family
HEP79_RS06370	COG0395	ABC-type sugar transport system, permease component
HEP79_RS06375	COG1175	transmembrane transport
HEP79_RS06380	COG1846	Transcriptional regulator
HEP79_RS06380	COG1940	carbohydrate kinase activity
HEP79_RS06405	COG1178	ABC-type Fe3 transport system permease component
HEP79_RS06410	COG3842	ATPase activity
HEP79_RS06415	COG1840	ABC-type Fe3 transport system, periplasmic component
HEP79_RS06440	COG4608	Belongs to the ABC transporter superfamily
HEP79_RS06445	COG0444	Belongs to the ABC transporter superfamily
HEP79_RS06465	COG2116	formate transmembrane transporter activity
HEP79_RS06475	COG0242	peptide deformylase activity
HEP79_RS06480	COG1970	mechanosensitive ion channel activity
HEP79_RS06505	COG1780	Probably involved in ribonucleotide reductase function
HEP79_RS06515	COG0431	NADPH-dependent FMN reductase
HEP79_RS06520	COG3226	Transcriptional regulator
HEP79_RS06525	COG0477	Major facilitator Superfamily
HEP79_RS06535	COG1834	amidinotransferase
HEP79_RS06540	COG0549	Belongs to the carbamate kinase family
HEP79_RS06545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEP79_RS06565	COG0395	ABC-type sugar transport system, permease component
HEP79_RS06580	COG0366	Alpha amylase catalytic
HEP79_RS06590	COG1473	amidohydrolase
HEP79_RS06595	COG0477	Major facilitator Superfamily
HEP79_RS06620	COG0012	GTP binding
HEP79_RS06625	COG1322	Protein conserved in bacteria
HEP79_RS06630	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HEP79_RS06640	COG1722	exodeoxyribonuclease VII activity
HEP79_RS06645	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEP79_RS06650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEP79_RS06660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HEP79_RS06665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HEP79_RS06670	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEP79_RS06685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEP79_RS06690	COG1012	belongs to the aldehyde dehydrogenase family
HEP79_RS06705	COG1131	(ABC) transporter
HEP79_RS06710	COG1725	Transcriptional regulator
HEP79_RS06755	COG0148	phosphopyruvate hydratase activity
HEP79_RS06770	COG0193	aminoacyl-tRNA hydrolase activity
HEP79_RS06775	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HEP79_RS06785	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEP79_RS06795	COG1309	transcriptional regulator
HEP79_RS06810	COG4152	abc transporter atp-binding protein
HEP79_RS06815	COG1668	transmembrane transport
HEP79_RS06825	COG0488	(ABC) transporter
HEP79_RS06830	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEP79_RS06835	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HEP79_RS06845	COG0084	hydrolase, TatD family'
HEP79_RS06850	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEP79_RS06885	COG1335	isochorismatase
HEP79_RS06905	COG2873	o-acetylhomoserine
HEP79_RS06925	COG1131	(ABC) transporter
HEP79_RS06940	COG2813	Specifically methylates the guanine in position
HEP79_RS06945	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HEP79_RS06970	COG1620	l-lactate permease
HEP79_RS06975	COG0247	lactate metabolic process
HEP79_RS06985	COG1556	Lactate utilization protein
HEP79_RS07005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HEP79_RS07010	COG2190	(PTS) system
HEP79_RS07015	COG1263	PTS System
HEP79_RS07015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HEP79_RS07035	COG1051	belongs to the nudix hydrolase family
HEP79_RS07045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEP79_RS07065	COG1511	domain protein
HEP79_RS07075	COG2848	UPF0210 protein
HEP79_RS07080	COG3830	Belongs to the UPF0237 family
HEP79_RS07095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HEP79_RS07100	COG0254	rRNA binding
HEP79_RS07105	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEP79_RS07110	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HEP79_RS07115	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HEP79_RS07130	COG0477	Major facilitator Superfamily
HEP79_RS07135	COG2267	carboxylic ester hydrolase activity
HEP79_RS07140	COG2188	Transcriptional regulator
HEP79_RS07145	COG1120	ATPase activity
HEP79_RS07150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEP79_RS07155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEP79_RS07160	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HEP79_RS07175	COG0596	Alpha beta hydrolase
HEP79_RS07190	COG3657	addiction module killer protein
HEP79_RS07195	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HEP79_RS07260	COG0791	NLP P60 protein
HEP79_RS07260	COG1388	LysM domain
HEP79_RS07270	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEP79_RS07275	COG2252	PERMEase
HEP79_RS07290	COG1278	Cold shock
HEP79_RS07300	COG1842	Phage shock protein A
HEP79_RS07310	COG0745	RESPONSE REGULATOR receiver
HEP79_RS07315	COG2205	protein histidine kinase activity
HEP79_RS07325	COG4221	oxidoreductase activity
HEP79_RS07335	COG0459	protein refolding
HEP79_RS07350	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEP79_RS07375	COG1131	(ABC) transporter
HEP79_RS07400	COG3842	ATPase activity
HEP79_RS07410	COG0673	inositol 2-dehydrogenase activity
HEP79_RS07420	COG1653	transport
HEP79_RS07425	COG1175	transmembrane transport
HEP79_RS07455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEP79_RS07470	COG1966	Carbon starvation protein
HEP79_RS07710	COG2233	PERMEase
HEP79_RS07725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEP79_RS07730	COG0215	cysteine-tRNA ligase activity
HEP79_RS07740	COG1136	(ABC) transporter
HEP79_RS07765	COG2376	Dihydroxyacetone kinase
HEP79_RS07780	COG3775	system Galactitol-specific IIC component
HEP79_RS07800	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HEP79_RS07805	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HEP79_RS07820	COG5002	protein histidine kinase activity
HEP79_RS07830	COG0588	phosphoglycerate mutase activity
HEP79_RS07870	COG1609	Transcriptional regulator
HEP79_RS07880	COG1175	transmembrane transport
HEP79_RS07885	COG0395	ABC-type sugar transport system, permease component
HEP79_RS07905	COG1120	ATPase activity
HEP79_RS07910	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEP79_RS07925	COG3345	alpha-galactosidase
HEP79_RS07935	COG0395	ABC-type sugar transport system, permease component
HEP79_RS07940	COG1175	transmembrane transport
HEP79_RS07970	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HEP79_RS07975	COG0667	Aldo Keto reductase
HEP79_RS07985	COG0710	3-dehydroquinate dehydratase activity
HEP79_RS08000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEP79_RS08005	COG1950	PFAM Membrane protein of
HEP79_RS08010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEP79_RS08015	COG0586	Pfam SNARE associated Golgi protein
HEP79_RS08050	COG1309	transcriptional regulator
HEP79_RS08060	COG1132	(ABC) transporter
HEP79_RS08065	COG1129	ABC transporter
HEP79_RS08085	COG1063	alcohol dehydrogenase
HEP79_RS08090	COG1609	Transcriptional regulator
HEP79_RS08095	COG2271	Major facilitator Superfamily
HEP79_RS08100	COG0483	inositol monophosphate 1-phosphatase activity
HEP79_RS08105	COG1879	ABC-type sugar transport system periplasmic component
HEP79_RS08110	COG1172	Belongs to the binding-protein-dependent transport system permease family
HEP79_RS08120	COG0673	inositol 2-dehydrogenase activity
HEP79_RS08130	COG0673	inositol 2-dehydrogenase activity
HEP79_RS08135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HEP79_RS08155	COG3718	enzyme involved in inositol metabolism
HEP79_RS08160	COG3962	Belongs to the TPP enzyme family
HEP79_RS08170	COG4604	ABC transporter, ATP-binding protein
HEP79_RS08175	COG4605	iron ion homeostasis
HEP79_RS08180	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEP79_RS08185	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HEP79_RS08190	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEP79_RS08200	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HEP79_RS08200	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
HEP79_RS08205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HEP79_RS08210	COG1904	glucuronate isomerase
HEP79_RS08225	COG3142	Participates in the control of copper homeostasis
HEP79_RS08240	COG1940	carbohydrate kinase activity
HEP79_RS08250	COG0601	transmembrane transport
HEP79_RS08255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEP79_RS08265	COG1940	carbohydrate kinase activity
HEP79_RS08270	COG1846	Transcriptional regulator
HEP79_RS08270	COG1940	carbohydrate kinase activity
HEP79_RS08280	COG1175	transmembrane transport
HEP79_RS08320	COG1129	ABC transporter
HEP79_RS08325	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEP79_RS08340	COG0471	metal ion transport
HEP79_RS08375	COG1172	Belongs to the binding-protein-dependent transport system permease family
HEP79_RS08385	COG1879	ABC-type sugar transport system periplasmic component
HEP79_RS08395	COG1070	Carbohydrate kinase
HEP79_RS08420	COG1252	NADH dehydrogenase
HEP79_RS08425	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HEP79_RS08465	COG1643	Atp-dependent helicase
HEP79_RS08480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HEP79_RS08510	COG0577	efflux transmembrane transporter activity
HEP79_RS08515	COG1136	(ABC) transporter
HEP79_RS08530	COG0745	RESPONSE REGULATOR receiver
HEP79_RS08535	COG2205	protein histidine kinase activity
HEP79_RS08540	COG0343	queuine tRNA-ribosyltransferase activity
HEP79_RS08550	COG1428	Deoxynucleoside kinase
HEP79_RS08595	COG0351	phosphomethylpyrimidine kinase
HEP79_RS08605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HEP79_RS08615	COG2814	Major facilitator Superfamily
HEP79_RS08620	COG0305	Participates in initiation and elongation during chromosome replication
HEP79_RS08635	COG0737	Belongs to the 5'-nucleotidase family
HEP79_RS08640	COG0359	binds to the 23S rRNA
HEP79_RS08645	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEP79_RS08655	COG0360	Binds together with S18 to 16S ribosomal RNA
HEP79_RS08660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HEP79_RS08665	COG0628	permease
HEP79_RS08675	COG0617	tRNA 3'-terminal CCA addition
HEP79_RS08700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HEP79_RS08705	COG1181	Belongs to the D-alanine--D-alanine ligase family
HEP79_RS08715	COG1192	Involved in chromosome partitioning
HEP79_RS08720	COG0357	Ribosomal RNA small subunit methyltransferase G
HEP79_RS08730	COG0706	membrane insertase activity
HEP79_RS08735	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HEP79_RS08740	COG0594	ribonuclease P activity
HEP79_RS08745	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HEP79_RS08750	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEP79_RS08755	COG0592	DNA-directed DNA polymerase activity
HEP79_RS08760	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEP79_RS08770	COG0187	DNA topoisomerase II activity
HEP79_RS08775	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEP79_RS08815	COG0705	Rhomboid family
HEP79_RS08825	COG3764	Sortase (surface protein transpeptidase)
HEP79_RS08860	COG0842	Transport permease protein
HEP79_RS08860	COG1716	ATPase activity
HEP79_RS08860	COG1131	(ABC) transporter
HEP79_RS08890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEP79_RS08895	COG1854	S-ribosylhomocysteine lyase activity
HEP79_RS08910	COG1780	Probably involved in ribonucleotide reductase function
HEP79_RS08915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEP79_RS08920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEP79_RS08930	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEP79_RS08935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEP79_RS08950	COG0395	ABC-type sugar transport system, permease component
HEP79_RS08955	COG1175	transmembrane transport
HEP79_RS08975	COG2072	flavoprotein involved in K transport
HEP79_RS08985	COG1643	Atp-dependent helicase
HEP79_RS08990	COG2197	response regulator
HEP79_RS08995	COG4585	Histidine kinase
HEP79_RS09005	COG1131	(ABC) transporter
HEP79_RS09015	COG1136	(ABC) transporter
HEP79_RS09025	COG2197	response regulator
HEP79_RS09035	COG1328	CTP reductase activity
HEP79_RS09060	COG1414	Transcriptional regulator
HEP79_RS09065	COG0246	Mannitol dehydrogenase
HEP79_RS09070	COG1312	Catalyzes the dehydration of D-mannonate
HEP79_RS09075	COG0800	Aldolase
HEP79_RS09080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEP79_RS09085	COG2226	methyltransferase
HEP79_RS09095	COG1120	ATPase activity
HEP79_RS09105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEP79_RS09120	COG1132	(ABC) transporter
HEP79_RS09125	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HEP79_RS09130	COG1609	Transcriptional regulator
HEP79_RS09145	COG1175	transmembrane transport
HEP79_RS09150	COG0395	ABC-type sugar transport system, permease component
HEP79_RS09160	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEP79_RS09210	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HEP79_RS09260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEP79_RS09260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEP79_RS09265	COG3617	BRO family, N-terminal domain
HEP79_RS09310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEP79_RS09340	COG4626	Terminase
HEP79_RS09340	COG1802	Transcriptional regulator
HEP79_RS09350	COG4695	Portal protein
HEP79_RS09425	COG4824	toxin secretion phage lysis holin
HEP79_RS09495	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEP79_RS09525	COG1172	Belongs to the binding-protein-dependent transport system permease family
HEP79_RS09530	COG1879	ABC-type sugar transport system periplasmic component
HEP79_RS09535	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HEP79_RS09535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HEP79_RS09540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEP79_RS09570	COG0561	phosphatase activity
HEP79_RS09575	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEP79_RS09585	COG0077	Prephenate dehydratase
HEP79_RS09610	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEP79_RS09630	COG4868	Belongs to the UPF0371 family
HEP79_RS09635	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HEP79_RS09685	COG0521	Mo-molybdopterin cofactor biosynthetic process
HEP79_RS09695	COG0315	cyclic pyranopterin monophosphate synthase activity
HEP79_RS09705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEP79_RS09730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HEP79_RS09765	COG0596	Alpha beta hydrolase
HEP79_RS09815	COG3655	Transcriptional regulator
HEP79_RS09825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HEP79_RS09825	COG2890	protein-(glutamine-N5) methyltransferase activity
HEP79_RS09830	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEP79_RS09830	COG1754	DNA topoisomerase type I activity
HEP79_RS09835	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEP79_RS09840	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEP79_RS09865	COG2801	Transposase and inactivated derivatives
HEP79_RS09915	COG0717	Belongs to the dCTP deaminase family
HEP79_RS09920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HEP79_RS09920	COG2111	Na H antiporter
HEP79_RS09960	COG4149	molybdate abc transporter
HEP79_RS09965	COG3842	ATPase activity
HEP79_RS09985	COG0662	Cupin 2, conserved barrel domain protein
HEP79_RS10015	COG1940	carbohydrate kinase activity
HEP79_RS10020	COG0390	transport system, permease component
HEP79_RS10030	COG1505	serine-type exopeptidase activity
HEP79_RS10040	COG0437	4 iron, 4 sulfur cluster binding
HEP79_RS10045	COG0243	molybdopterin cofactor binding
HEP79_RS10050	COG1937	Protein conserved in bacteria
HEP79_RS10055	COG0446	pyridine nucleotide-disulphide oxidoreductase
HEP79_RS10075	COG0243	molybdopterin cofactor binding
HEP79_RS10085	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEP79_RS10090	COG0540	Belongs to the ATCase OTCase family
HEP79_RS10095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HEP79_RS10100	COG0284	orotidine-5'-phosphate decarboxylase activity
HEP79_RS10105	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEP79_RS10115	COG0443	Heat shock 70 kDa protein
HEP79_RS10120	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEP79_RS10125	COG0484	heat shock protein binding
HEP79_RS10130	COG0789	Transcriptional regulator
HEP79_RS10150	COG0584	glycerophosphoryl diester phosphodiesterase
HEP79_RS10155	COG0823	Involved in the tonB-independent uptake of proteins
HEP79_RS10155	COG1506	peptidase
HEP79_RS10165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEP79_RS10210	COG0494	nUDIX hydrolase
HEP79_RS10225	COG0191	fructose-bisphosphate aldolase activity
HEP79_RS10235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEP79_RS10240	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HEP79_RS10245	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HEP79_RS10250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HEP79_RS10280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HEP79_RS10310	COG0039	L-malate dehydrogenase activity
HEP79_RS10315	COG0728	peptidoglycan biosynthetic process
HEP79_RS10340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEP79_RS10365	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HEP79_RS10390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HEP79_RS10395	COG0306	phosphate transporter
HEP79_RS10405	COG1115	amino acid carrier protein
HEP79_RS10415	COG0737	Belongs to the 5'-nucleotidase family
HEP79_RS10425	COG3485	protocatechuate 3,4-dioxygenase
HEP79_RS10430	COG0354	folic acid binding
HEP79_RS10440	COG1490	D-aminoacyl-tRNA deacylase activity
HEP79_RS10460	COG0738	Major facilitator superfamily
HEP79_RS10465	COG2390	Transcriptional regulator
HEP79_RS10485	COG1349	DNA-binding transcription factor activity
HEP79_RS10505	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEP79_RS10510	COG2376	Dihydroxyacetone kinase
HEP79_RS10520	COG0698	ribose 5-phosphate isomerase
HEP79_RS10525	COG0730	response to heat
HEP79_RS10530	COG0641	radical SAM
HEP79_RS10535	COG2814	Major facilitator Superfamily
HEP79_RS10540	COG1609	Transcriptional regulator
HEP79_RS10545	COG3119	arylsulfatase activity
HEP79_RS10555	COG0395	ABC-type sugar transport system, permease component
HEP79_RS10570	COG1501	Belongs to the glycosyl hydrolase 31 family
HEP79_RS10580	COG1349	DNA-binding transcription factor activity
HEP79_RS10590	COG1175	transmembrane transport
HEP79_RS10595	COG0395	ABC-type sugar transport system, permease component
HEP79_RS10620	COG2115	Belongs to the xylose isomerase family
HEP79_RS10625	COG1070	Carbohydrate kinase
HEP79_RS10630	COG4213	ABC transporter substrate-binding protein
HEP79_RS10640	COG4214	carbohydrate transport
HEP79_RS10645	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HEP79_RS10650	COG1757	Na H antiporter
HEP79_RS10660	COG3250	beta-galactosidase activity
HEP79_RS10670	COG0395	ABC-type sugar transport system, permease component
HEP79_RS10680	COG1609	Transcriptional regulator
HEP79_RS10690	COG0395	ABC-type sugar transport system, permease component
HEP79_RS10695	COG1175	transmembrane transport
HEP79_RS10710	COG3250	beta-galactosidase activity
HEP79_RS10720	COG1609	Transcriptional regulator
HEP79_RS10730	COG2610	gluconate transmembrane transporter activity
HEP79_RS10750	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HEP79_RS10755	COG3250	beta-galactosidase activity
HEP79_RS10760	COG1869	D-ribose catabolic process
HEP79_RS10765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEP79_RS10770	COG1879	ABC-type sugar transport system periplasmic component
HEP79_RS10775	COG1172	Belongs to the binding-protein-dependent transport system permease family
HEP79_RS10780	COG1129	ABC transporter
HEP79_RS10785	COG1609	Transcriptional regulator
HEP79_RS10790	COG2226	methyltransferase
HEP79_RS10795	COG1116	anion transmembrane transporter activity
HEP79_RS10815	COG0737	Belongs to the 5'-nucleotidase family
HEP79_RS10830	COG1609	Transcriptional regulator
HEP79_RS10835	COG2271	Major facilitator Superfamily
HEP79_RS10840	COG1285	pathogenesis
HEP79_RS10870	COG1131	(ABC) transporter
HEP79_RS10885	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1