locus-tag	class	description
J4179_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J4179_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J4179_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
J4179_RS00025	COG0187	DNA topoisomerase II activity
J4179_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J4179_RS00085	COG3764	Sortase (surface protein transpeptidase)
J4179_RS00100	COG0768	penicillin binding
J4179_RS00120	COG1716	ATPase activity
J4179_RS00120	COG1131	(ABC) transporter
J4179_RS00120	COG0842	Transport permease protein
J4179_RS00155	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J4179_RS00160	COG1854	S-ribosylhomocysteine lyase activity
J4179_RS00175	COG1780	Probably involved in ribonucleotide reductase function
J4179_RS00180	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4179_RS00185	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J4179_RS00190	COG3253	May function as heme-dependent peroxidase
J4179_RS00195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J4179_RS00205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J4179_RS00235	COG1653	transport
J4179_RS00240	COG0395	ABC-type sugar transport system, permease component
J4179_RS00245	COG1175	transmembrane transport
J4179_RS00265	COG1643	Atp-dependent helicase
J4179_RS00270	COG2197	response regulator
J4179_RS00280	COG1136	(ABC) transporter
J4179_RS00290	COG2197	response regulator
J4179_RS00305	COG1328	CTP reductase activity
J4179_RS00320	COG1414	Transcriptional regulator
J4179_RS00325	COG0246	Mannitol dehydrogenase
J4179_RS00330	COG1312	Catalyzes the dehydration of D-mannonate
J4179_RS00335	COG0800	Aldolase
J4179_RS00340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4179_RS00345	COG1609	Transcriptional regulator
J4179_RS00360	COG1175	transmembrane transport
J4179_RS00365	COG0395	ABC-type sugar transport system, permease component
J4179_RS00375	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J4179_RS00400	COG2188	Transcriptional regulator
J4179_RS00410	COG1172	Belongs to the binding-protein-dependent transport system permease family
J4179_RS00415	COG1879	ABC-type sugar transport system periplasmic component
J4179_RS00420	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J4179_RS00420	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J4179_RS00425	COG1486	melibiose metabolic process
J4179_RS00450	COG1175	transmembrane transport
J4179_RS00460	COG1846	Transcriptional regulator
J4179_RS00460	COG1940	carbohydrate kinase activity
J4179_RS00465	COG1940	carbohydrate kinase activity
J4179_RS00475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J4179_RS00480	COG0601	transmembrane transport
J4179_RS00490	COG1940	carbohydrate kinase activity
J4179_RS00505	COG3142	Participates in the control of copper homeostasis
J4179_RS00525	COG0179	Fumarylacetoacetate (FAA) hydrolase
J4179_RS00530	COG1012	belongs to the aldehyde dehydrogenase family
J4179_RS00540	COG0477	Major facilitator Superfamily
J4179_RS00545	COG1802	Transcriptional regulator
J4179_RS00555	COG3971	2-oxopent-4-enoate hydratase activity
J4179_RS00570	COG1904	glucuronate isomerase
J4179_RS00575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
J4179_RS00595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4179_RS00610	COG4605	iron ion homeostasis
J4179_RS00615	COG4604	ABC transporter, ATP-binding protein
J4179_RS00630	COG2217	Heavy metal translocating P-type atpase
J4179_RS00645	COG0586	Pfam SNARE associated Golgi protein
J4179_RS00650	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J4179_RS00655	COG3001	Fructosamine kinase
J4179_RS00660	COG1950	PFAM Membrane protein of
J4179_RS00665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J4179_RS00680	COG0714	Associated with various cellular activities
J4179_RS00710	COG0710	3-dehydroquinate dehydratase activity
J4179_RS00730	COG0667	Aldo Keto reductase
J4179_RS00735	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J4179_RS00760	COG3345	alpha-galactosidase
J4179_RS00800	COG4626	Terminase
J4179_RS00800	COG1802	Transcriptional regulator
J4179_RS00845	COG3177	Filamentation induced by cAMP protein fic
J4179_RS00860	COG0717	Belongs to the dCTP deaminase family
J4179_RS00865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4179_RS00865	COG2111	Na H antiporter
J4179_RS00870	COG1006	Multisubunit Na H antiporter MnhC subunit
J4179_RS00875	COG0651	ATP synthesis coupled electron transport
J4179_RS00885	COG2212	antiporter activity
J4179_RS00900	COG4143	(ABC) transporter
J4179_RS00910	COG3842	ATPase activity
J4179_RS00925	COG0662	Cupin 2, conserved barrel domain protein
J4179_RS00935	COG1940	carbohydrate kinase activity
J4179_RS00940	COG0390	transport system, permease component
J4179_RS00950	COG1505	serine-type exopeptidase activity
J4179_RS00960	COG0437	4 iron, 4 sulfur cluster binding
J4179_RS00965	COG0243	molybdopterin cofactor binding
J4179_RS00970	COG1937	Protein conserved in bacteria
J4179_RS00975	COG0446	pyridine nucleotide-disulphide oxidoreductase
J4179_RS00990	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J4179_RS00995	COG0540	Belongs to the ATCase OTCase family
J4179_RS01000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J4179_RS01005	COG0284	orotidine-5'-phosphate decarboxylase activity
J4179_RS01010	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J4179_RS01025	COG0167	dihydroorotate dehydrogenase activity
J4179_RS01030	COG0443	Heat shock 70 kDa protein
J4179_RS01035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J4179_RS01040	COG0484	heat shock protein binding
J4179_RS01045	COG0789	Transcriptional regulator
J4179_RS01055	COG0584	glycerophosphoryl diester phosphodiesterase
J4179_RS01060	COG1506	peptidase
J4179_RS01060	COG0823	Involved in the tonB-independent uptake of proteins
J4179_RS01075	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J4179_RS01080	COG3949	Membrane
J4179_RS01135	COG0494	nUDIX hydrolase
J4179_RS01155	COG0191	fructose-bisphosphate aldolase activity
J4179_RS01165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J4179_RS01170	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
J4179_RS01175	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J4179_RS01185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J4179_RS01195	COG0557	exoribonuclease II activity
J4179_RS01220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4179_RS01255	COG0039	L-malate dehydrogenase activity
J4179_RS01270	COG2348	transferase activity, transferring amino-acyl groups
J4179_RS01275	COG2348	transferase activity, transferring amino-acyl groups
J4179_RS01285	COG2826	transposase and inactivated derivatives, IS30 family
J4179_RS01310	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4179_RS01335	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J4179_RS01340	COG0494	nUDIX hydrolase
J4179_RS01340	COG0406	alpha-ribazole phosphatase activity
J4179_RS01345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J4179_RS01360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J4179_RS01365	COG0306	phosphate transporter
J4179_RS01375	COG1115	amino acid carrier protein
J4179_RS01385	COG3485	protocatechuate 3,4-dioxygenase
J4179_RS01405	COG1490	D-aminoacyl-tRNA deacylase activity
J4179_RS01415	COG1063	alcohol dehydrogenase
J4179_RS01420	COG2610	gluconate transmembrane transporter activity
J4179_RS01425	COG0246	Mannitol dehydrogenase
J4179_RS01435	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J4179_RS01450	COG0738	Major facilitator superfamily
J4179_RS01455	COG2390	Transcriptional regulator
J4179_RS01465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
J4179_RS01470	COG1070	Carbohydrate kinase
J4179_RS01495	COG2376	Dihydroxyacetone kinase
J4179_RS01505	COG0698	ribose 5-phosphate isomerase
J4179_RS01525	COG3250	beta-galactosidase activity
J4179_RS01535	COG2226	methyltransferase
J4179_RS01555	COG0730	response to heat
J4179_RS01560	COG0641	radical SAM
J4179_RS01565	COG2271	Major facilitator Superfamily
J4179_RS01570	COG1609	Transcriptional regulator
J4179_RS01575	COG3119	arylsulfatase activity
J4179_RS01580	COG1252	NADH dehydrogenase
J4179_RS01590	COG1609	Transcriptional regulator
J4179_RS01600	COG3250	beta-galactosidase activity
J4179_RS01615	COG1175	transmembrane transport
J4179_RS01620	COG0395	ABC-type sugar transport system, permease component
J4179_RS01630	COG1715	Restriction endonuclease
J4179_RS01635	COG2610	gluconate transmembrane transporter activity
J4179_RS01640	COG3048	D-serine ammonia-lyase activity
J4179_RS01645	COG2964	Protein conserved in bacteria
J4179_RS01680	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J4179_RS01740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4179_RS01745	COG0574	Belongs to the PEP-utilizing enzyme family
J4179_RS01745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4179_RS01765	COG0366	Alpha amylase catalytic
J4179_RS01770	COG0395	ABC-type sugar transport system, permease component
J4179_RS01775	COG1175	transmembrane transport
J4179_RS01810	COG0247	lactate metabolic process
J4179_RS01810	COG0277	FAD linked oxidase domain protein
J4179_RS01820	COG2267	carboxylic ester hydrolase activity
J4179_RS01825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J4179_RS01830	COG0791	NLP P60 protein
J4179_RS01835	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J4179_RS01850	COG0037	tRNA processing
J4179_RS01855	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J4179_RS01860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J4179_RS01865	COG0302	gtp cyclohydrolase
J4179_RS01870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J4179_RS01875	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J4179_RS01895	COG1609	Transcriptional regulator
J4179_RS01915	COG3250	beta-galactosidase activity
J4179_RS01920	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J4179_RS01920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4179_RS01925	COG1461	Dihydroxyacetone kinase
J4179_RS01930	COG2376	Dihydroxyacetone kinase
J4179_RS01940	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J4179_RS01945	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J4179_RS01955	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J4179_RS01960	COG2409	Drug exporters of the RND superfamily
J4179_RS01965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J4179_RS01970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J4179_RS01990	COG0247	lactate metabolic process
J4179_RS02000	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
J4179_RS02005	COG2390	Transcriptional regulator
J4179_RS02010	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J4179_RS02020	COG1194	a g-specific adenine glycosylase
J4179_RS02030	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
J4179_RS02035	COG0569	domain protein
J4179_RS02040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4179_RS02060	COG2801	Transposase and inactivated derivatives
J4179_RS02070	COG0406	alpha-ribazole phosphatase activity
J4179_RS02095	COG0395	ABC-type sugar transport system, permease component
J4179_RS02100	COG1177	transmembrane transport
J4179_RS02105	COG1653	transport
J4179_RS02110	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
J4179_RS02115	COG4948	Mandelate Racemase Muconate Lactonizing
J4179_RS02120	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
J4179_RS02135	COG2226	methyltransferase
J4179_RS02140	COG0644	oxidoreductase
J4179_RS02150	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J4179_RS02155	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J4179_RS02160	COG0649	NAD binding
J4179_RS02170	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J4179_RS02175	COG1034	ATP synthesis coupled electron transport
J4179_RS02180	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J4179_RS02185	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J4179_RS02195	COG0713	ATP synthesis coupled electron transport
J4179_RS02200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J4179_RS02210	COG1007	ATP synthesis coupled electron transport
J4179_RS02215	COG0142	geranyltranstransferase activity
J4179_RS02220	COG0653	protein targeting
J4179_RS02260	COG0419	ATPase involved in DNA repair
J4179_RS02265	COG0420	3'-5' exonuclease activity
J4179_RS02270	COG0483	inositol monophosphate 1-phosphatase activity
J4179_RS02280	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J4179_RS02295	COG0657	acetylesterase activity
J4179_RS02305	COG0747	negative chemotaxis
J4179_RS02310	COG0601	transmembrane transport
J4179_RS02315	COG0444	Belongs to the ABC transporter superfamily
J4179_RS02320	COG4608	Belongs to the ABC transporter superfamily
J4179_RS02325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4179_RS02330	COG1846	Transcriptional regulator
J4179_RS02330	COG1940	carbohydrate kinase activity
J4179_RS02335	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
J4179_RS02340	COG0363	glucosamine-6-phosphate deaminase activity
J4179_RS02345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
J4179_RS02350	COG1595	DNA-templated transcription, initiation
J4179_RS02360	COG3103	Sh3 type 3 domain protein
J4179_RS02360	COG0791	NLP P60 protein
J4179_RS02360	COG1388	LysM domain
J4179_RS02370	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4179_RS02370	COG0567	Dehydrogenase, E1 component
J4179_RS02375	COG1253	flavin adenine dinucleotide binding
J4179_RS02385	COG1388	LysM domain
J4179_RS02385	COG4942	peptidase
J4179_RS02430	COG0018	arginyl-trna synthetase
J4179_RS02435	COG0019	diaminopimelate decarboxylase activity
J4179_RS02440	COG0460	homoserine dehydrogenase
J4179_RS02445	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4179_RS02450	COG0083	homoserine kinase activity
J4179_RS02465	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J4179_RS02470	COG2890	protein-(glutamine-N5) methyltransferase activity
J4179_RS02490	COG0356	it plays a direct role in the translocation of protons across the membrane
J4179_RS02495	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J4179_RS02500	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J4179_RS02505	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J4179_RS02510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J4179_RS02515	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J4179_RS02520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J4179_RS02535	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
J4179_RS02565	COG0366	Alpha amylase catalytic
J4179_RS02580	COG1175	transmembrane transport
J4179_RS02585	COG3833	ABC-type maltose transport systems, permease component
J4179_RS02600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
J4179_RS02615	COG0366	Alpha amylase catalytic
J4179_RS02625	COG1136	(ABC) transporter
J4179_RS02625	COG0577	efflux transmembrane transporter activity
J4179_RS02640	COG0058	SHG alpha-glucan phosphorylase activity
J4179_RS02645	COG0180	Tryptophanyl-tRNA synthetase
J4179_RS02675	COG3480	Lon protease (S16) C-terminal proteolytic domain
J4179_RS02685	COG1615	UPF0182 protein
J4179_RS02690	COG1470	cell adhesion involved in biofilm formation
J4179_RS02690	COG0366	Alpha amylase catalytic
J4179_RS02715	COG3547	Transposase (IS116 IS110 IS902 family)
J4179_RS02725	COG1725	Transcriptional regulator
J4179_RS02730	COG1131	(ABC) transporter
J4179_RS02740	COG0387	Pfam Sodium calcium exchanger
J4179_RS02750	COG1053	succinate dehydrogenase
J4179_RS02755	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4179_RS02770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J4179_RS02775	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J4179_RS02790	COG4989	oxidoreductase activity
J4179_RS02805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4179_RS02815	COG4585	Histidine kinase
J4179_RS02820	COG2135	peptidase activity
J4179_RS02825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J4179_RS02830	COG1404	Belongs to the peptidase S8 family
J4179_RS02845	COG2801	Transposase and inactivated derivatives
J4179_RS02850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J4179_RS02855	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J4179_RS02860	COG0154	amidase activity
J4179_RS02865	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J4179_RS02895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J4179_RS02925	COG0129	dihydroxy-acid dehydratase activity
J4179_RS02930	COG2985	domain, Protein
J4179_RS02930	COG0569	domain protein
J4179_RS02940	COG0440	acetolactate synthase activity
J4179_RS02945	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J4179_RS02965	COG0473	3-isopropylmalate dehydrogenase activity
J4179_RS02970	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J4179_RS02975	COG1882	Formate acetyltransferase
J4179_RS03010	COG4750	Nucleotidyl transferase
J4179_RS03015	COG3475	LICD family
J4179_RS03020	COG1216	Glycosyl transferase, family 2
J4179_RS03020	COG1442	glycosyl transferase family 8
J4179_RS03045	COG2244	polysaccharide biosynthetic process
J4179_RS03050	COG0463	Glycosyl transferase, family 2
J4179_RS03050	COG1216	Glycosyl transferase, family 2
J4179_RS03075	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J4179_RS03085	COG1162	GTPase activity
J4179_RS03115	COG1263	PTS System
J4179_RS03115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4179_RS03115	COG2190	(PTS) system
J4179_RS03120	COG2818	Glycosylase
J4179_RS03135	COG2354	Protein conserved in bacteria
J4179_RS03140	COG3590	peptidase
J4179_RS03150	COG1045	serine acetyltransferase
J4179_RS03160	COG1739	Uncharacterized protein family UPF0029
J4179_RS03190	COG0393	Putative heavy-metal-binding
J4179_RS03215	COG0667	Aldo Keto reductase
J4179_RS03220	COG0544	peptidyl-prolyl cis-trans isomerase activity
J4179_RS03225	COG0740	serine-type endopeptidase activity
J4179_RS03230	COG0740	serine-type endopeptidase activity
J4179_RS03240	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J4179_RS03245	COG1605	Chorismate mutase
J4179_RS03245	COG0287	Prephenate dehydrogenase
J4179_RS03265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J4179_RS03280	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J4179_RS03285	COG0285	dihydrofolate synthase activity
J4179_RS03295	COG0105	UTP biosynthetic process
J4179_RS03310	COG3069	C4-dicarboxylate transmembrane transporter activity
J4179_RS03315	COG1473	amidohydrolase
J4179_RS03335	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
J4179_RS03345	COG1837	Belongs to the UPF0109 family
J4179_RS03350	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J4179_RS03360	COG0335	large ribosomal subunit rRNA binding
J4179_RS03365	COG0681	Belongs to the peptidase S26 family
J4179_RS03370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J4179_RS03380	COG0792	nuclease activity
J4179_RS03395	COG4974	Belongs to the 'phage' integrase family
J4179_RS03405	COG2860	membrane
J4179_RS03410	COG0052	Belongs to the universal ribosomal protein uS2 family
J4179_RS03415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J4179_RS03425	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
J4179_RS03430	COG0644	oxidoreductase
J4179_RS03450	COG0528	UMP kinase activity
J4179_RS03455	COG0233	cytoplasmic translational termination
J4179_RS03465	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J4179_RS03475	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J4179_RS03480	COG0750	zinc metalloprotease
J4179_RS03485	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J4179_RS03495	COG0442	prolyl-tRNA aminoacylation
J4179_RS03505	COG0779	Required for maturation of 30S ribosomal subunits
J4179_RS03520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J4179_RS03525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J4179_RS03530	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J4179_RS03535	COG5002	protein histidine kinase activity
J4179_RS03545	COG2271	Major facilitator Superfamily
J4179_RS03555	COG3842	ATPase activity
J4179_RS03585	COG1131	(ABC) transporter
J4179_RS03650	COG1185	polyribonucleotide nucleotidyltransferase activity
J4179_RS03660	COG0612	Peptidase, M16
J4179_RS03665	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J4179_RS03670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J4179_RS03685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J4179_RS03690	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J4179_RS03695	COG1674	ftsk spoiiie
J4179_RS03710	COG1058	Belongs to the CinA family
J4179_RS03710	COG1546	Belongs to the CinA family
J4179_RS03715	COG1396	sequence-specific DNA binding
J4179_RS03725	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
J4179_RS03730	COG2137	regulation of response to DNA damage stimulus
J4179_RS03735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J4179_RS03740	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J4179_RS03745	COG2813	Specifically methylates the guanine in position
J4179_RS03750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J4179_RS03770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J4179_RS03775	COG0318	PFAM AMP-dependent synthetase and ligase
J4179_RS03780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J4179_RS03805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J4179_RS03815	COG2001	Belongs to the MraZ family
J4179_RS03820	COG0275	rRNA processing
J4179_RS03830	COG0768	penicillin binding
J4179_RS03835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J4179_RS03840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J4179_RS03845	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J4179_RS03850	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J4179_RS03860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J4179_RS03865	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J4179_RS03875	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J4179_RS03880	COG1496	oxidoreductase activity
J4179_RS03885	COG1799	cell septum assembly
J4179_RS03900	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
J4179_RS03915	COG0587	DNA-directed DNA polymerase activity
J4179_RS03920	COG2501	S4 domain
J4179_RS03935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4179_RS03940	COG1121	(ABC) transporter
J4179_RS03950	COG0423	glycine-tRNA ligase activity
J4179_RS03960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J4179_RS03975	COG0358	DNA primase activity
J4179_RS03985	COG0805	protein transport
J4179_RS03990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4179_RS03995	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J4179_RS04025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4179_RS04030	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
J4179_RS04070	COG1090	epimerase
J4179_RS04090	COG0009	L-threonylcarbamoyladenylate synthase
J4179_RS04110	COG0477	Major facilitator Superfamily
J4179_RS04115	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
J4179_RS04145	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J4179_RS04150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J4179_RS04155	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J4179_RS04175	COG1940	carbohydrate kinase activity
J4179_RS04190	COG0174	glutamine synthetase
J4179_RS04195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J4179_RS04215	COG4584	PFAM Integrase catalytic
J4179_RS04245	COG0174	glutamine synthetase
J4179_RS04265	COG0508	dehydrogenase complex catalyzes the overall conversion of
J4179_RS04270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4179_RS04280	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J4179_RS04295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4179_RS04345	COG0205	6-phosphofructokinase activity
J4179_RS04350	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
J4179_RS04355	COG2815	serine threonine protein kinase
J4179_RS04355	COG0515	serine threonine protein kinase
J4179_RS04370	COG0142	geranyltranstransferase activity
J4179_RS04385	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J4179_RS04400	COG0187	DNA topoisomerase II activity
J4179_RS04415	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J4179_RS04460	COG0569	domain protein
J4179_RS04475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J4179_RS04480	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J4179_RS04485	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J4179_RS04545	COG2197	response regulator
J4179_RS04550	COG1760	l-serine dehydratase
J4179_RS04555	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J4179_RS04560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J4179_RS04570	COG0438	transferase activity, transferring glycosyl groups
J4179_RS04590	COG0217	transcriptional regulatory protein
J4179_RS04595	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J4179_RS04600	COG0632	four-way junction helicase activity
J4179_RS04605	COG2255	four-way junction helicase activity
J4179_RS04615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4179_RS04620	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J4179_RS04625	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
J4179_RS04630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J4179_RS04640	COG1196	nuclear chromosome segregation
J4179_RS04650	COG0124	histidyl-tRNA synthetase
J4179_RS04655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J4179_RS04660	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J4179_RS04675	COG2814	Major facilitator Superfamily
J4179_RS04680	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J4179_RS04695	COG2409	Drug exporters of the RND superfamily
J4179_RS04705	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J4179_RS04715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J4179_RS04720	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J4179_RS04740	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J4179_RS04755	COG2217	Heavy metal translocating P-type atpase
J4179_RS04760	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J4179_RS04765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J4179_RS04770	COG0505	Belongs to the CarA family
J4179_RS04775	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
J4179_RS04785	COG0194	GDP metabolic process
J4179_RS04790	COG1758	RNA polymerase activity
J4179_RS04800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J4179_RS04810	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J4179_RS04820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J4179_RS04825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J4179_RS04830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J4179_RS04835	COG0140	phosphoribosyl-ATP diphosphatase activity
J4179_RS04840	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J4179_RS04880	COG1216	Glycosyl transferase, family 2
J4179_RS04905	COG1716	ATPase activity
J4179_RS04915	COG1834	amidinotransferase
J4179_RS04925	COG0205	6-phosphofructokinase activity
J4179_RS04930	COG1160	GTP binding
J4179_RS04935	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J4179_RS04945	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J4179_RS04970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J4179_RS04985	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J4179_RS04990	COG0149	triose-phosphate isomerase activity
J4179_RS04995	COG0126	phosphoglycerate kinase activity
J4179_RS05000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J4179_RS05005	COG1481	regulation of sporulation
J4179_RS05020	COG0322	excinuclease ABC activity
J4179_RS05045	COG0556	nucleotide-excision repair
J4179_RS05050	COG0237	dephospho-CoA kinase activity
J4179_RS05055	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
J4179_RS05060	COG0539	negative regulation of cytoplasmic translation
J4179_RS05065	COG2226	methyltransferase
J4179_RS05090	COG0469	pyruvate kinase activity
J4179_RS05095	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J4179_RS05105	COG0159	tryptophan synthase activity
J4179_RS05110	COG0133	tryptophan synthase activity
J4179_RS05115	COG0134	indole-3-glycerol-phosphate synthase activity
J4179_RS05125	COG0107	imidazoleglycerol-phosphate synthase activity
J4179_RS05140	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
J4179_RS05150	COG4122	O-methyltransferase activity
J4179_RS05155	COG1222	aaa ATPase
J4179_RS05170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J4179_RS05175	COG1968	undecaprenyl-diphosphatase activity
J4179_RS05190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4179_RS05195	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
J4179_RS05200	COG0519	Catalyzes the synthesis of GMP from XMP
J4179_RS05205	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J4179_RS05225	COG0587	DNA-directed DNA polymerase activity
J4179_RS05240	COG1881	PFAM PEBP family protein
J4179_RS05245	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J4179_RS05260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4179_RS05275	COG1119	ATPase activity
J4179_RS05280	COG0297	glycogen (starch) synthase activity
J4179_RS05290	COG3830	Belongs to the UPF0237 family
J4179_RS05290	COG0560	Phosphoserine phosphatase
J4179_RS05305	COG0488	(ABC) transporter
J4179_RS05315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J4179_RS05320	COG2151	metal-sulfur cluster biosynthetic enzyme
J4179_RS05345	COG0719	Fe-S assembly protein
J4179_RS05365	COG0728	peptidoglycan biosynthetic process
J4179_RS05385	COG0497	DNA recombination
J4179_RS05390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J4179_RS05405	COG0647	UMP catabolic process
J4179_RS05435	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4179_RS05440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4179_RS05445	COG1121	(ABC) transporter
J4179_RS05455	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J4179_RS05470	COG1476	TRANSCRIPTIONal
J4179_RS05475	COG0165	Argininosuccinate lyase
J4179_RS05480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J4179_RS05485	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J4179_RS05495	COG0137	argininosuccinate synthase activity
J4179_RS05505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J4179_RS05510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J4179_RS05515	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J4179_RS05520	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J4179_RS05530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J4179_RS05535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J4179_RS05555	COG1902	pentaerythritol trinitrate reductase activity
J4179_RS05560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4179_RS05575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J4179_RS05580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J4179_RS05590	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J4179_RS05595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J4179_RS05605	COG0131	Imidazoleglycerol-phosphate dehydratase
J4179_RS05615	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J4179_RS05620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4179_RS05625	COG1381	Involved in DNA repair and RecF pathway recombination
J4179_RS05630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J4179_RS05645	COG0631	protein serine/threonine phosphatase activity
J4179_RS05665	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J4179_RS05680	COG0484	heat shock protein binding
J4179_RS05685	COG1420	regulation of RNA biosynthetic process
J4179_RS05705	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J4179_RS05710	COG0481	GTPase activity
J4179_RS05730	COG3237	CsbD-like
J4179_RS05735	COG0268	Binds directly to 16S ribosomal RNA
J4179_RS05740	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
J4179_RS05745	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J4179_RS05760	COG1596	polysaccharide export
J4179_RS05760	COG1555	photosystem II stabilization
J4179_RS05765	COG0433	COG0433 Predicted ATPase
J4179_RS05775	COG0495	leucyl-tRNA aminoacylation
J4179_RS05800	COG0813	purine-nucleoside phosphorylase activity
J4179_RS05805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4179_RS05805	COG1321	iron dependent repressor
J4179_RS05810	COG1435	thymidine kinase activity
J4179_RS05840	COG1121	(ABC) transporter
J4179_RS05845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J4179_RS05865	COG0671	phosphoesterase, PA-phosphatase related
J4179_RS05885	COG1113	amino acid transport
J4179_RS05895	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J4179_RS05895	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J4179_RS05900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J4179_RS05905	COG2011	ABC-type metal ion transport system permease component
J4179_RS05915	COG1113	amino acid transport
J4179_RS05925	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J4179_RS05930	COG0826	peptidase U32
J4179_RS05935	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
J4179_RS05940	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
J4179_RS05945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4179_RS05965	COG1609	Transcriptional regulator
J4179_RS05970	COG3250	beta-galactosidase activity
J4179_RS06000	COG0133	tryptophan synthase activity
J4179_RS06025	COG0406	alpha-ribazole phosphatase activity
J4179_RS06030	COG0799	negative regulation of ribosome biogenesis
J4179_RS06040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J4179_RS06045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J4179_RS06055	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J4179_RS06060	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J4179_RS06065	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J4179_RS06070	COG1530	ribonuclease E activity
J4179_RS06075	COG1271	oxidase subunit
J4179_RS06080	COG1294	oxidase, subunit
J4179_RS06085	COG4988	ABC transporter
J4179_RS06100	COG1132	(ABC) transporter
J4179_RS06105	COG1132	(ABC) transporter
J4179_RS06125	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J4179_RS06130	COG0571	ribonuclease III activity
J4179_RS06145	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J4179_RS06155	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J4179_RS06160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J4179_RS06180	COG1181	Belongs to the D-alanine--D-alanine ligase family
J4179_RS06190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J4179_RS06205	COG0066	3-isopropylmalate dehydratase activity
J4179_RS06210	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J4179_RS06220	COG0438	transferase activity, transferring glycosyl groups
J4179_RS06235	COG4975	Glucose uptake
J4179_RS06240	COG0339	signal peptide processing
J4179_RS06300	COG0179	Fumarylacetoacetate (FAA) hydrolase
J4179_RS06305	COG1022	Amp-dependent synthetase and ligase
J4179_RS06330	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
J4179_RS06335	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J4179_RS06340	COG1234	tRNA 3'-trailer cleavage
J4179_RS06345	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J4179_RS06355	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J4179_RS06380	COG2985	domain, Protein
J4179_RS06380	COG0569	domain protein
J4179_RS06395	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J4179_RS06405	COG0737	Belongs to the 5'-nucleotidase family
J4179_RS06425	COG0778	Nitroreductase
J4179_RS06505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J4179_RS06515	COG0352	thiamine-phosphate diphosphorylase activity
J4179_RS06520	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
J4179_RS06525	COG0477	Major facilitator Superfamily
J4179_RS06530	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J4179_RS06530	COG0352	thiamine-phosphate diphosphorylase activity
J4179_RS06530	COG0351	phosphomethylpyrimidine kinase
J4179_RS06540	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J4179_RS06560	COG1619	proteins homologs of microcin C7 resistance protein MccF
J4179_RS06570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J4179_RS06575	COG0739	heme binding
J4179_RS06580	COG2177	Part of the ABC transporter FtsEX involved in
J4179_RS06585	COG2884	Cell division ATP-binding protein ftsE
J4179_RS06590	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
J4179_RS06665	COG0513	Belongs to the DEAD box helicase family
J4179_RS06670	COG2095	MarC family integral membrane protein
J4179_RS06680	COG0006	proline dipeptidase activity
J4179_RS06685	COG2239	Acts as a magnesium transporter
J4179_RS06710	COG1611	Belongs to the LOG family
J4179_RS06720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J4179_RS06725	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
J4179_RS06745	COG1079	Belongs to the binding-protein-dependent transport system permease family
J4179_RS06750	COG4603	Belongs to the binding-protein-dependent transport system permease family
J4179_RS06755	COG3845	ABC transporter
J4179_RS06760	COG1744	ABC transporter substrate-binding protein PnrA-like
J4179_RS06780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J4179_RS06785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J4179_RS06795	COG1268	BioY protein
J4179_RS06800	COG0736	holo-[acyl-carrier-protein] synthase activity
J4179_RS06805	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J4179_RS06810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J4179_RS06815	COG4770	biotin carboxylase activity
J4179_RS06835	COG0644	oxidoreductase
J4179_RS06860	COG2271	Major facilitator Superfamily
J4179_RS06865	COG2030	dehydratase
J4179_RS06895	COG0110	maltose O-acetyltransferase activity
J4179_RS06905	COG0039	L-malate dehydrogenase activity
J4179_RS06920	COG0166	Belongs to the GPI family
J4179_RS06925	COG0205	6-phosphofructokinase activity
J4179_RS06935	COG0138	bifunctional purine biosynthesis protein purh
J4179_RS06955	COG0045	succinate-CoA ligase (ADP-forming) activity
J4179_RS06960	COG2755	lipolytic protein G-D-S-L family
J4179_RS06960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J4179_RS06970	COG5646	InterPro IPR014922
J4179_RS06990	COG0564	pseudouridine synthase activity
J4179_RS06995	COG0857	belongs to the CobB CobQ family
J4179_RS06995	COG0280	phosphate acetyltransferase
J4179_RS07000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J4179_RS07015	COG0726	polysaccharide deacetylase
J4179_RS07025	COG1136	(ABC) transporter
J4179_RS07040	COG0114	fumarate hydratase activity
J4179_RS07045	COG0516	GMP reductase activity
J4179_RS07065	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J4179_RS07070	COG0151	Belongs to the GarS family
J4179_RS07075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J4179_RS07080	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J4179_RS07085	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
J4179_RS07090	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J4179_RS07095	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J4179_RS07115	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J4179_RS07130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J4179_RS07135	COG0733	neurotransmitter:sodium symporter activity
J4179_RS07145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J4179_RS07150	COG1053	succinate dehydrogenase
J4179_RS07175	COG0802	atpase or kinase
J4179_RS07180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J4179_RS07190	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J4179_RS07195	COG1072	(Pantothenic acid kinase))
J4179_RS07205	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J4179_RS07210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J4179_RS07220	COG4720	Psort location CytoplasmicMembrane, score
J4179_RS07225	COG1122	ATPase activity
J4179_RS07230	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J4179_RS07245	COG0101	tRNA pseudouridine synthase activity
J4179_RS07250	COG1940	carbohydrate kinase activity
J4179_RS07260	COG0765	amino acid transport
J4179_RS07265	COG1126	abc transporter atp-binding protein
J4179_RS07270	COG0640	Transcriptional regulator
J4179_RS07280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J4179_RS07290	COG0789	Transcriptional regulator
J4179_RS07295	COG0203	ribosomal protein L17
J4179_RS07300	COG0202	RNA polymerase activity
J4179_RS07310	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J4179_RS07315	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4179_RS07320	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J4179_RS07325	COG0024	Methionine aminopeptidase
J4179_RS07330	COG0563	adenylate kinase activity
J4179_RS07345	COG0200	Binds to the 23S rRNA
J4179_RS07350	COG1841	ribosomal large subunit assembly
J4179_RS07355	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
J4179_RS07365	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J4179_RS07370	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J4179_RS07375	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J4179_RS07380	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J4179_RS07385	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J4179_RS07390	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J4179_RS07405	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J4179_RS07410	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J4179_RS07415	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J4179_RS07420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J4179_RS07425	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
J4179_RS07430	COG0089	rRNA binding
J4179_RS07435	COG0088	Forms part of the polypeptide exit tunnel
J4179_RS07440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J4179_RS07445	COG0051	transcription antitermination factor activity, RNA binding
J4179_RS07455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
J4179_RS07460	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J4179_RS07465	COG0049	tRNA binding
J4179_RS07470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J4179_RS07475	COG0833	amino acid
J4179_RS07480	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
J4179_RS07485	COG0085	RNA polymerase activity
J4179_RS07490	COG0222	ribosome binding
J4179_RS07495	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J4179_RS07500	COG0572	uridine kinase
J4179_RS07505	COG0081	regulation of translation
J4179_RS07510	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
J4179_RS07530	COG0436	Aminotransferase
J4179_RS07540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J4179_RS07555	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J4179_RS07560	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J4179_RS07580	COG1666	GTP binding
J4179_RS07590	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J4179_RS07600	COG5401	PFAM Sporulation and spore germination
J4179_RS07605	COG5002	protein histidine kinase activity
J4179_RS07610	COG0745	RESPONSE REGULATOR receiver
J4179_RS07630	COG0714	Associated with various cellular activities
J4179_RS07675	COG0483	inositol monophosphate 1-phosphatase activity
J4179_RS07690	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
J4179_RS07730	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J4179_RS07780	COG0673	inositol 2-dehydrogenase activity
J4179_RS07790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J4179_RS07805	COG1088	dTDP-glucose 4,6-dehydratase activity
J4179_RS07825	COG1316	TRANSCRIPTIONal
J4179_RS07835	COG0642	Histidine kinase
J4179_RS07840	COG0745	RESPONSE REGULATOR receiver
J4179_RS07855	COG0424	maF-like protein
J4179_RS07890	COG1217	gtp-binding protein TYPA
J4179_RS07900	COG1132	(ABC) transporter
J4179_RS07905	COG1132	(ABC) transporter
J4179_RS07930	COG0321	lipoyl(octanoyl) transferase activity
J4179_RS07935	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J4179_RS07945	COG1362	aminopeptidase activity
J4179_RS07960	COG2838	Isocitrate dehydrogenase
J4179_RS07965	COG2391	methyltransferase activity
J4179_RS07970	COG0425	Belongs to the sulfur carrier protein TusA family
J4179_RS07990	COG2116	formate transmembrane transporter activity
J4179_RS08000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J4179_RS08010	COG0242	peptide deformylase activity
J4179_RS08015	COG1970	mechanosensitive ion channel activity
J4179_RS08040	COG0778	Nitroreductase
J4179_RS08065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J4179_RS08065	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4179_RS08145	COG0012	GTP binding
J4179_RS08150	COG1322	Protein conserved in bacteria
J4179_RS08155	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J4179_RS08160	COG1570	exodeoxyribonuclease VII activity
J4179_RS08165	COG1722	exodeoxyribonuclease VII activity
J4179_RS08170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J4179_RS08175	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J4179_RS08185	COG2326	polyphosphate kinase activity
J4179_RS08195	COG2801	Transposase and inactivated derivatives
J4179_RS08200	COG2326	polyphosphate kinase activity
J4179_RS08205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
J4179_RS08210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J4179_RS08215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J4179_RS08225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J4179_RS08230	COG1012	belongs to the aldehyde dehydrogenase family
J4179_RS08245	COG1131	(ABC) transporter
J4179_RS08275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J4179_RS08300	COG0148	phosphopyruvate hydratase activity
J4179_RS08315	COG0193	aminoacyl-tRNA hydrolase activity
J4179_RS08325	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J4179_RS08330	COG1136	(ABC) transporter
J4179_RS08340	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J4179_RS08355	COG4152	abc transporter atp-binding protein
J4179_RS08360	COG1668	transmembrane transport
J4179_RS08370	COG0488	(ABC) transporter
J4179_RS08375	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J4179_RS08380	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J4179_RS08390	COG0084	hydrolase, TatD family'
J4179_RS08395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J4179_RS08405	COG1335	isochorismatase
J4179_RS08425	COG2873	o-acetylhomoserine
J4179_RS08435	COG1131	(ABC) transporter
J4179_RS08450	COG2813	Specifically methylates the guanine in position
J4179_RS08455	COG0667	Aldo Keto reductase
J4179_RS08460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J4179_RS08475	COG1120	ATPase activity
J4179_RS08480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4179_RS08490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J4179_RS08515	COG1620	l-lactate permease
J4179_RS08520	COG0247	lactate metabolic process
J4179_RS08530	COG1556	Lactate utilization protein
J4179_RS08535	COG2826	transposase and inactivated derivatives, IS30 family
J4179_RS08565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
J4179_RS08565	COG1263	PTS System
J4179_RS08580	COG1131	(ABC) transporter
J4179_RS08585	COG1051	belongs to the nudix hydrolase family
J4179_RS08595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J4179_RS08620	COG1511	domain protein
J4179_RS08630	COG2848	UPF0210 protein
J4179_RS08635	COG3830	Belongs to the UPF0237 family
J4179_RS08640	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J4179_RS08645	COG0254	rRNA binding
J4179_RS08650	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J4179_RS08655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J4179_RS08660	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J4179_RS08690	COG0477	Major facilitator Superfamily
J4179_RS08695	COG0657	acetylesterase activity
J4179_RS08700	COG2188	Transcriptional regulator
J4179_RS08705	COG1120	ATPase activity
J4179_RS08710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4179_RS08715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J4179_RS08720	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
J4179_RS08735	COG0596	Alpha beta hydrolase
J4179_RS08755	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J4179_RS08820	COG1321	iron dependent repressor
J4179_RS08830	COG2252	PERMEase
J4179_RS08835	COG1482	cell wall glycoprotein biosynthetic process
J4179_RS08845	COG1278	Cold shock
J4179_RS08855	COG1842	Phage shock protein A
J4179_RS08865	COG0745	RESPONSE REGULATOR receiver
J4179_RS08870	COG2205	protein histidine kinase activity
J4179_RS08880	COG4221	oxidoreductase activity
J4179_RS08890	COG0459	protein refolding
J4179_RS08905	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J4179_RS08915	COG0395	ABC-type sugar transport system, permease component
J4179_RS08920	COG1175	transmembrane transport
J4179_RS08940	COG1609	Transcriptional regulator
J4179_RS08965	COG3842	ATPase activity
J4179_RS08980	COG1653	transport
J4179_RS08985	COG1175	transmembrane transport
J4179_RS09015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J4179_RS09060	COG2233	PERMEase
J4179_RS09075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J4179_RS09080	COG0215	cysteine-tRNA ligase activity
J4179_RS09090	COG1136	(ABC) transporter
J4179_RS09110	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J4179_RS09115	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J4179_RS09125	COG0745	RESPONSE REGULATOR receiver
J4179_RS09135	COG0704	Plays a role in the regulation of phosphate uptake
J4179_RS09145	COG0588	phosphoglycerate mutase activity
J4179_RS09185	COG4974	Belongs to the 'phage' integrase family
J4179_RS09195	COG1192	Involved in chromosome partitioning
J4179_RS09220	COG2184	nucleotidyltransferase activity
J4179_RS09320	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J4179_RS09325	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J4179_RS09330	COG1754	DNA topoisomerase type I activity
J4179_RS09330	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J4179_RS09345	COG3655	Transcriptional regulator
J4179_RS09350	COG1205	dead DEAH box helicase
J4179_RS09350	COG1111	helicase
J4179_RS09395	COG0596	Alpha beta hydrolase
J4179_RS09425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4179_RS09455	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J4179_RS09465	COG0315	cyclic pyranopterin monophosphate synthase activity
J4179_RS09475	COG0521	Mo-molybdopterin cofactor biosynthetic process
J4179_RS09530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J4179_RS09535	COG4868	Belongs to the UPF0371 family
J4179_RS09540	COG1114	Component of the transport system for branched-chain amino acids
J4179_RS09550	COG0590	tRNA wobble adenosine to inosine editing
J4179_RS09555	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
J4179_RS09570	COG1215	transferase activity, transferring glycosyl groups
J4179_RS09580	COG0077	Prephenate dehydratase
J4179_RS09590	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J4179_RS09595	COG0561	phosphatase activity
J4179_RS09620	COG0471	metal ion transport
J4179_RS09650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J4179_RS09675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
J4179_RS09690	COG1643	Atp-dependent helicase
J4179_RS09700	COG0569	domain protein
J4179_RS09705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J4179_RS09720	COG2801	Transposase and inactivated derivatives
J4179_RS09735	COG0577	efflux transmembrane transporter activity
J4179_RS09735	COG1136	(ABC) transporter
J4179_RS09740	COG0577	efflux transmembrane transporter activity
J4179_RS09740	COG1136	(ABC) transporter
J4179_RS09755	COG0745	RESPONSE REGULATOR receiver
J4179_RS09760	COG2205	protein histidine kinase activity
J4179_RS09765	COG0343	queuine tRNA-ribosyltransferase activity
J4179_RS09775	COG1428	Deoxynucleoside kinase
J4179_RS09790	COG2801	Transposase and inactivated derivatives
J4179_RS09825	COG0656	L-ascorbic acid biosynthetic process
J4179_RS09830	COG0351	phosphomethylpyrimidine kinase
J4179_RS09845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J4179_RS09850	COG0084	hydrolase, TatD family'
J4179_RS09860	COG0305	Participates in initiation and elongation during chromosome replication
J4179_RS09880	COG0359	binds to the 23S rRNA
J4179_RS09885	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J4179_RS09895	COG0360	Binds together with S18 to 16S ribosomal RNA
J4179_RS09900	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J4179_RS09905	COG0628	permease
J4179_RS09935	COG0492	ferredoxin-NADP+ reductase activity
J4179_RS09940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J4179_RS09945	COG1181	Belongs to the D-alanine--D-alanine ligase family
J4179_RS09960	COG0357	Ribosomal RNA small subunit methyltransferase G
J4179_RS09970	COG0706	membrane insertase activity
J4179_RS09975	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
J4179_RS09980	COG0594	ribonuclease P activity
J4179_RS09985	COG0230	Belongs to the bacterial ribosomal protein bL34 family