locus-tag	class	description
ASU32_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ASU32_RS00020	COG0592	DNA-directed DNA polymerase activity
ASU32_RS00025	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ASU32_RS00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ASU32_RS00040	COG0477	Major facilitator Superfamily
ASU32_RS00050	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
ASU32_RS00060	COG0187	DNA topoisomerase II activity
ASU32_RS00065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ASU32_RS00090	COG1253	flavin adenine dinucleotide binding
ASU32_RS00140	COG2815	serine threonine protein kinase
ASU32_RS00140	COG0515	serine threonine protein kinase
ASU32_RS00145	COG0515	serine threonine protein kinase
ASU32_RS00150	COG0768	penicillin binding
ASU32_RS00165	COG1716	ATPase activity
ASU32_RS00170	COG1716	ATPase activity
ASU32_RS00190	COG1278	Cold shock
ASU32_RS00375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASU32_RS00505	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ASU32_RS00525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASU32_RS00530	COG0798	PFAM Bile acid sodium symporter
ASU32_RS00535	COG0640	Transcriptional regulator
ASU32_RS00540	COG1695	Transcriptional regulator
ASU32_RS00560	COG2199	diguanylate cyclase activity
ASU32_RS00560	COG2203	Gaf domain
ASU32_RS00590	COG1278	Cold shock
ASU32_RS00620	COG3177	Filamentation induced by cAMP protein fic
ASU32_RS00640	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASU32_RS00675	COG3706	GGDEF domain
ASU32_RS00710	COG0297	glycogen (starch) synthase activity
ASU32_RS00755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ASU32_RS00765	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASU32_RS00825	COG1012	belongs to the aldehyde dehydrogenase family
ASU32_RS00845	COG2957	Belongs to the agmatine deiminase family
ASU32_RS00855	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ASU32_RS00885	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS00920	COG1073	alpha beta
ASU32_RS00955	COG3336	cytochrome c oxidase
ASU32_RS00965	COG0657	acetylesterase activity
ASU32_RS00985	COG0778	Nitroreductase
ASU32_RS00990	COG1376	ErfK ybiS ycfS ynhG family protein
ASU32_RS01015	COG0745	RESPONSE REGULATOR receiver
ASU32_RS01020	COG2205	protein histidine kinase activity
ASU32_RS01035	COG0659	secondary active sulfate transmembrane transporter activity
ASU32_RS01045	COG0745	RESPONSE REGULATOR receiver
ASU32_RS01050	COG2205	protein histidine kinase activity
ASU32_RS01065	COG3559	Exporter of polyketide antibiotics
ASU32_RS01070	COG1131	(ABC) transporter
ASU32_RS01080	COG0667	Aldo Keto reductase
ASU32_RS01085	COG0390	transport system, permease component
ASU32_RS01090	COG0067	glutamate synthase
ASU32_RS01090	COG0069	glutamate synthase activity
ASU32_RS01090	COG0070	glutamate synthase
ASU32_RS01110	COG2501	S4 domain
ASU32_RS01125	COG1012	belongs to the aldehyde dehydrogenase family
ASU32_RS01140	COG2755	lipolytic protein G-D-S-L family
ASU32_RS01155	COG1216	Glycosyl transferase, family 2
ASU32_RS01165	COG1674	ftsk spoiiie
ASU32_RS01250	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ASU32_RS01280	COG2119	membrane
ASU32_RS01340	COG1316	TRANSCRIPTIONal
ASU32_RS01350	COG2252	PERMEase
ASU32_RS01360	COG3226	Transcriptional regulator
ASU32_RS01410	COG0813	purine-nucleoside phosphorylase activity
ASU32_RS01425	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASU32_RS01445	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ASU32_RS01445	COG2146	nitrite reductase [NAD(P)H] activity
ASU32_RS01455	COG0561	phosphatase activity
ASU32_RS01465	COG2385	sporulation resulting in formation of a cellular spore
ASU32_RS01475	COG1216	Glycosyl transferase, family 2
ASU32_RS01480	COG0671	phosphoesterase, PA-phosphatase related
ASU32_RS01485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ASU32_RS01490	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ASU32_RS01500	COG5001	Diguanylate cyclase
ASU32_RS01500	COG5002	protein histidine kinase activity
ASU32_RS01520	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ASU32_RS01525	COG4223	transferase activity, transferring acyl groups other than amino-acyl groups
ASU32_RS01530	COG2957	Belongs to the agmatine deiminase family
ASU32_RS01535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS01545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASU32_RS01545	COG3321	synthase
ASU32_RS01545	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ASU32_RS01550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASU32_RS01555	COG0277	FAD linked oxidase domain protein
ASU32_RS01565	COG1309	transcriptional regulator
ASU32_RS01580	COG1956	GAF domain-containing protein
ASU32_RS01610	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ASU32_RS01615	COG1349	DNA-binding transcription factor activity
ASU32_RS01625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ASU32_RS01625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASU32_RS01625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ASU32_RS01640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASU32_RS01650	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ASU32_RS01655	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ASU32_RS01690	COG3191	aminopeptidase activity
ASU32_RS01700	COG1846	Transcriptional regulator
ASU32_RS01715	COG1309	transcriptional regulator
ASU32_RS01740	COG0583	DNA-binding transcription factor activity
ASU32_RS01760	COG1396	sequence-specific DNA binding
ASU32_RS01770	COG1760	l-serine dehydratase
ASU32_RS01785	COG3214	Protein conserved in bacteria
ASU32_RS01790	COG2184	nucleotidyltransferase activity
ASU32_RS01795	COG0488	(ABC) transporter
ASU32_RS01820	COG0464	growth
ASU32_RS01830	COG1674	ftsk spoiiie
ASU32_RS01875	COG1404	Belongs to the peptidase S8 family
ASU32_RS01905	COG1309	transcriptional regulator
ASU32_RS01910	COG0183	Belongs to the thiolase family
ASU32_RS01915	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASU32_RS01915	COG1024	Enoyl-CoA hydratase
ASU32_RS01930	COG3590	peptidase
ASU32_RS02000	COG1309	transcriptional regulator
ASU32_RS02055	COG2409	Drug exporters of the RND superfamily
ASU32_RS02065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ASU32_RS02100	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ASU32_RS02105	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS02115	COG2030	dehydratase
ASU32_RS02125	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS02130	COG1309	transcriptional regulator
ASU32_RS02135	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ASU32_RS02135	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASU32_RS02165	COG0577	efflux transmembrane transporter activity
ASU32_RS02165	COG1136	(ABC) transporter
ASU32_RS02170	COG0577	efflux transmembrane transporter activity
ASU32_RS02175	COG1252	NADH dehydrogenase
ASU32_RS02180	COG1595	DNA-templated transcription, initiation
ASU32_RS02210	COG0492	ferredoxin-NADP+ reductase activity
ASU32_RS02270	COG4981	capsule polysaccharide biosynthetic process
ASU32_RS02290	COG1472	Belongs to the glycosyl hydrolase 3 family
ASU32_RS02295	COG1309	transcriptional regulator
ASU32_RS02305	COG2030	dehydratase
ASU32_RS02310	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS02315	COG0183	Belongs to the thiolase family
ASU32_RS02320	COG1832	CoA-binding protein
ASU32_RS02345	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS02365	COG0477	Major facilitator Superfamily
ASU32_RS02375	COG1115	amino acid carrier protein
ASU32_RS02395	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS02405	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ASU32_RS02405	COG2066	Belongs to the glutaminase family
ASU32_RS02410	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASU32_RS02420	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ASU32_RS02480	COG2181	nitrate reductase activity
ASU32_RS02480	COG0247	lactate metabolic process
ASU32_RS02500	COG1309	transcriptional regulator
ASU32_RS02505	COG2072	flavoprotein involved in K transport
ASU32_RS02530	COG0708	Exodeoxyribonuclease III
ASU32_RS02590	COG0443	Heat shock 70 kDa protein
ASU32_RS02595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ASU32_RS02600	COG0484	heat shock protein binding
ASU32_RS02605	COG0789	Transcriptional regulator
ASU32_RS02640	COG2267	carboxylic ester hydrolase activity
ASU32_RS02660	COG2149	membrane
ASU32_RS02720	COG0488	(ABC) transporter
ASU32_RS02725	COG0586	Pfam SNARE associated Golgi protein
ASU32_RS02730	COG0586	Pfam SNARE associated Golgi protein
ASU32_RS02760	COG4129	membrane
ASU32_RS02770	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ASU32_RS02785	COG2814	Major facilitator Superfamily
ASU32_RS02790	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ASU32_RS02810	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS02850	COG1690	Belongs to the RtcB family
ASU32_RS02870	COG0442	prolyl-tRNA aminoacylation
ASU32_RS02895	COG2027	D-alanyl-D-alanine carboxypeptidase
ASU32_RS02905	COG0037	tRNA processing
ASU32_RS02910	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ASU32_RS02930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASU32_RS02935	COG0302	gtp cyclohydrolase
ASU32_RS02940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASU32_RS02945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ASU32_RS02970	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ASU32_RS02975	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ASU32_RS02980	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ASU32_RS02990	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ASU32_RS03005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASU32_RS03015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASU32_RS03040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASU32_RS03045	COG4221	oxidoreductase activity
ASU32_RS03050	COG1309	transcriptional regulator
ASU32_RS03055	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ASU32_RS03060	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS03070	COG1194	a g-specific adenine glycosylase
ASU32_RS03075	COG0288	reversible hydration of carbon dioxide
ASU32_RS03085	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ASU32_RS03090	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ASU32_RS03105	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ASU32_RS03120	COG0215	cysteine-tRNA ligase activity
ASU32_RS03125	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASU32_RS03135	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ASU32_RS03140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ASU32_RS03145	COG1121	(ABC) transporter
ASU32_RS03185	COG2267	carboxylic ester hydrolase activity
ASU32_RS03190	COG0438	transferase activity, transferring glycosyl groups
ASU32_RS03225	COG0477	Major facilitator Superfamily
ASU32_RS03230	COG0640	Transcriptional regulator
ASU32_RS03245	COG0667	Aldo Keto reductase
ASU32_RS03255	COG2318	DinB family
ASU32_RS03270	COG1119	ATPase activity
ASU32_RS03275	COG4106	trans-aconitate 2-methyltransferase activity
ASU32_RS03280	COG0583	DNA-binding transcription factor activity
ASU32_RS03285	COG2814	Major facilitator Superfamily
ASU32_RS03290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS03300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ASU32_RS03315	COG0588	phosphoglycerate mutase activity
ASU32_RS03325	COG5002	protein histidine kinase activity
ASU32_RS03330	COG0745	RESPONSE REGULATOR receiver
ASU32_RS03370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ASU32_RS03405	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ASU32_RS03410	COG0181	hydroxymethylbilane synthase activity
ASU32_RS03415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASU32_RS03415	COG1648	precorrin-2 dehydrogenase activity
ASU32_RS03460	COG2608	mercury ion transmembrane transporter activity
ASU32_RS03465	COG2954	triphosphatase activity
ASU32_RS03470	COG2409	Drug exporters of the RND superfamily
ASU32_RS03480	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ASU32_RS03485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASU32_RS03490	COG2011	ABC-type metal ion transport system permease component
ASU32_RS03510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASU32_RS03515	COG3540	Alkaline phosphatase
ASU32_RS03520	COG2272	Belongs to the type-B carboxylesterase lipase family
ASU32_RS03525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASU32_RS03530	COG3654	unkown
ASU32_RS03540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ASU32_RS03545	COG0406	alpha-ribazole phosphatase activity
ASU32_RS03550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASU32_RS03555	COG0785	Cytochrome C biogenesis protein
ASU32_RS03565	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ASU32_RS03580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASU32_RS03600	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS03635	COG3629	intracellular signal transduction
ASU32_RS03675	COG4948	Mandelate Racemase Muconate Lactonizing
ASU32_RS03695	COG0154	amidase activity
ASU32_RS03710	COG1937	Protein conserved in bacteria
ASU32_RS03715	COG3268	Saccharopine dehydrogenase
ASU32_RS03720	COG3180	Ammonia monooxygenase
ASU32_RS03730	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ASU32_RS03740	COG0438	transferase activity, transferring glycosyl groups
ASU32_RS03745	COG2226	methyltransferase
ASU32_RS03750	COG0142	geranyltranstransferase activity
ASU32_RS03765	COG1666	GTP binding
ASU32_RS03790	COG2030	dehydratase
ASU32_RS03795	COG2030	dehydratase
ASU32_RS03815	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ASU32_RS03820	COG0081	regulation of translation
ASU32_RS03860	COG0222	ribosome binding
ASU32_RS03895	COG3618	amidohydrolase
ASU32_RS03920	COG0601	transmembrane transport
ASU32_RS03930	COG0444	Belongs to the ABC transporter superfamily
ASU32_RS03940	COG0747	negative chemotaxis
ASU32_RS03955	COG0179	Fumarylacetoacetate (FAA) hydrolase
ASU32_RS03960	COG4948	Mandelate Racemase Muconate Lactonizing
ASU32_RS03965	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS03975	COG2186	Transcriptional regulator
ASU32_RS04005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASU32_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS04040	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS04045	COG2508	Transcriptional regulator
ASU32_RS04060	COG1073	alpha beta
ASU32_RS04075	COG0535	radical SAM domain protein
ASU32_RS04105	COG2376	Dihydroxyacetone kinase
ASU32_RS04140	COG1024	Enoyl-CoA hydratase
ASU32_RS04150	COG0640	Transcriptional regulator
ASU32_RS04155	COG0765	amino acid transport
ASU32_RS04160	COG1126	abc transporter atp-binding protein
ASU32_RS04170	COG0384	phenazine biosynthesis protein PhzF
ASU32_RS04175	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ASU32_RS04180	COG1263	PTS System
ASU32_RS04185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ASU32_RS04210	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ASU32_RS04235	COG2188	Transcriptional regulator
ASU32_RS04245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS04260	COG1309	transcriptional regulator
ASU32_RS04275	COG1984	allophanate hydrolase subunit 2
ASU32_RS04285	COG0439	Biotin carboxylase
ASU32_RS04290	COG0511	ligase activity, forming carbon-carbon bonds
ASU32_RS04340	COG1061	Type III restriction enzyme res subunit
ASU32_RS04365	COG4941	Belongs to the sigma-70 factor family
ASU32_RS04420	COG1278	Cold shock
ASU32_RS04430	COG0477	Major facilitator Superfamily
ASU32_RS04440	COG2814	Major facilitator Superfamily
ASU32_RS04485	COG2814	Major facilitator Superfamily
ASU32_RS04500	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ASU32_RS04510	COG0259	pyridoxamine-phosphate oxidase activity
ASU32_RS04530	COG4221	oxidoreductase activity
ASU32_RS04550	COG0545	Peptidyl-prolyl cis-trans isomerase
ASU32_RS04590	COG0656	L-ascorbic acid biosynthetic process
ASU32_RS04595	COG2072	flavoprotein involved in K transport
ASU32_RS04625	COG1408	metallophosphoesterase
ASU32_RS04635	COG0328	RNA-DNA hybrid ribonuclease activity
ASU32_RS04670	COG1218	3'(2'),5'-bisphosphate nucleotidase
ASU32_RS04675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ASU32_RS04695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASU32_RS04700	COG2364	Membrane
ASU32_RS04715	COG2084	Dehydrogenase
ASU32_RS04720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASU32_RS04730	COG0166	Belongs to the GPI family
ASU32_RS04740	COG3119	arylsulfatase activity
ASU32_RS04755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ASU32_RS04770	COG4424	Sulfotransferase
ASU32_RS04780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASU32_RS04810	COG0739	heme binding
ASU32_RS04815	COG1116	anion transmembrane transporter activity
ASU32_RS04825	COG1285	pathogenesis
ASU32_RS04835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASU32_RS04845	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS04860	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS04865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASU32_RS04900	COG0045	succinate-CoA ligase (ADP-forming) activity
ASU32_RS04910	COG2814	Major facilitator Superfamily
ASU32_RS04945	COG0640	Transcriptional regulator
ASU32_RS04960	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ASU32_RS04985	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ASU32_RS04990	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ASU32_RS05000	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASU32_RS05010	COG0254	rRNA binding
ASU32_RS05020	COG2860	membrane
ASU32_RS05025	COG0745	RESPONSE REGULATOR receiver
ASU32_RS05030	COG2205	protein histidine kinase activity
ASU32_RS05035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASU32_RS05040	COG0521	Mo-molybdopterin cofactor biosynthetic process
ASU32_RS05110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ASU32_RS05115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ASU32_RS05125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ASU32_RS05150	COG3384	dioxygenase
ASU32_RS05155	COG1733	regulation of RNA biosynthetic process
ASU32_RS05175	COG5473	translation initiation factor activity
ASU32_RS05190	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASU32_RS05195	COG0596	Alpha beta hydrolase
ASU32_RS05205	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ASU32_RS05220	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASU32_RS05260	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ASU32_RS05265	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ASU32_RS05270	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ASU32_RS05280	COG0477	Major facilitator Superfamily
ASU32_RS05325	COG0084	hydrolase, TatD family'
ASU32_RS05330	COG3583	domain protein
ASU32_RS05335	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ASU32_RS05340	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ASU32_RS05355	COG0488	(ABC) transporter
ASU32_RS05375	COG1280	lysine exporter protein (LysE YggA)
ASU32_RS05395	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ASU32_RS05405	COG0193	aminoacyl-tRNA hydrolase activity
ASU32_RS05410	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ASU32_RS05430	COG5001	Diguanylate cyclase
ASU32_RS05440	COG0542	response to heat
ASU32_RS05450	COG2837	iron assimilation
ASU32_RS05475	COG1393	Belongs to the ArsC family
ASU32_RS05490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ASU32_RS05540	COG3956	TIGRFAM MazG family protein
ASU32_RS05560	COG1073	alpha beta
ASU32_RS05565	COG1309	transcriptional regulator
ASU32_RS05590	COG0713	ATP synthesis coupled electron transport
ASU32_RS05605	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ASU32_RS05610	COG1034	ATP synthesis coupled electron transport
ASU32_RS05625	COG0649	NAD binding
ASU32_RS05630	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASU32_RS05635	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ASU32_RS05655	COG0148	phosphopyruvate hydratase activity
ASU32_RS05680	COG2311	Membrane
ASU32_RS05695	COG0668	transmembrane transport
ASU32_RS05700	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ASU32_RS05730	COG2755	lipolytic protein G-D-S-L family
ASU32_RS05755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ASU32_RS05770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ASU32_RS05780	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ASU32_RS05800	COG1331	Highly conserved protein containing a thioredoxin domain
ASU32_RS05805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ASU32_RS05825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASU32_RS05830	COG4521	taurine ABC transporter
ASU32_RS05835	COG1116	anion transmembrane transporter activity
ASU32_RS05865	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ASU32_RS05875	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ASU32_RS05880	COG0456	acetyltransferase
ASU32_RS05910	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ASU32_RS05910	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ASU32_RS05955	COG1570	exodeoxyribonuclease VII activity
ASU32_RS05970	COG3599	regulation of cell shape
ASU32_RS05980	COG1322	Protein conserved in bacteria
ASU32_RS05985	COG0628	permease
ASU32_RS05990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASU32_RS05990	COG2169	Transcriptional regulator
ASU32_RS06005	COG1966	Carbon starvation protein
ASU32_RS06015	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASU32_RS06025	COG0012	GTP binding
ASU32_RS06080	COG2814	Major facilitator Superfamily
ASU32_RS06095	COG0604	alcohol dehydrogenase
ASU32_RS06115	COG2832	Protein of unknown function (DUF454)
ASU32_RS06125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASU32_RS06225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASU32_RS06235	COG3383	formate dehydrogenase (NAD+) activity
ASU32_RS06235	COG0243	molybdopterin cofactor binding
ASU32_RS06240	COG0243	molybdopterin cofactor binding
ASU32_RS06240	COG3383	formate dehydrogenase (NAD+) activity
ASU32_RS06245	COG0437	4 iron, 4 sulfur cluster binding
ASU32_RS06255	COG0709	Synthesizes selenophosphate from selenide and ATP
ASU32_RS06295	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASU32_RS06305	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS06335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASU32_RS06340	COG0058	SHG alpha-glucan phosphorylase activity
ASU32_RS06345	COG1940	carbohydrate kinase activity
ASU32_RS06355	COG1609	Transcriptional regulator
ASU32_RS06360	COG0738	Major facilitator superfamily
ASU32_RS06390	COG3842	ATPase activity
ASU32_RS06395	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ASU32_RS06405	COG0667	Aldo Keto reductase
ASU32_RS06430	COG0747	negative chemotaxis
ASU32_RS06435	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ASU32_RS06445	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ASU32_RS06455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ASU32_RS06470	COG3220	belongs to the UPF0276 family
ASU32_RS06485	COG0183	Belongs to the thiolase family
ASU32_RS06490	COG0596	Alpha beta hydrolase
ASU32_RS06495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ASU32_RS06505	COG4829	muconolactone delta-isomerase
ASU32_RS06510	COG3485	protocatechuate 3,4-dioxygenase
ASU32_RS06520	COG0583	DNA-binding transcription factor activity
ASU32_RS06525	COG4638	Rieske (2fe-2S)
ASU32_RS06560	COG2239	Acts as a magnesium transporter
ASU32_RS06565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASU32_RS06570	COG1611	Belongs to the LOG family
ASU32_RS06575	COG1611	Belongs to the LOG family
ASU32_RS06580	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS06585	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ASU32_RS06590	COG0463	Glycosyl transferase, family 2
ASU32_RS06595	COG0789	Transcriptional regulator
ASU32_RS06620	COG0297	glycogen (starch) synthase activity
ASU32_RS06625	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ASU32_RS06650	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ASU32_RS06680	COG1482	cell wall glycoprotein biosynthetic process
ASU32_RS06690	COG1132	(ABC) transporter
ASU32_RS06695	COG0531	amino acid
ASU32_RS06705	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ASU32_RS06720	COG2239	Acts as a magnesium transporter
ASU32_RS06775	COG0366	Alpha amylase catalytic
ASU32_RS06780	COG1609	Transcriptional regulator
ASU32_RS06790	COG0598	Magnesium transport protein CorA
ASU32_RS06805	COG1309	transcriptional regulator
ASU32_RS06810	COG0567	Dehydrogenase, E1 component
ASU32_RS06810	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASU32_RS06830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASU32_RS06865	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS06875	COG2814	Major facilitator Superfamily
ASU32_RS06880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ASU32_RS06890	COG3706	GGDEF domain
ASU32_RS06920	COG0018	arginyl-trna synthetase
ASU32_RS06930	COG0460	homoserine dehydrogenase
ASU32_RS06935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ASU32_RS06940	COG0083	homoserine kinase activity
ASU32_RS06955	COG0254	rRNA binding
ASU32_RS06960	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ASU32_RS06965	COG2890	protein-(glutamine-N5) methyltransferase activity
ASU32_RS07015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASU32_RS07020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASU32_RS07035	COG0356	it plays a direct role in the translocation of protons across the membrane
ASU32_RS07040	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ASU32_RS07055	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ASU32_RS07060	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ASU32_RS07065	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ASU32_RS07070	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ASU32_RS07105	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
ASU32_RS07125	COG0183	Belongs to the thiolase family
ASU32_RS07150	COG1175	transmembrane transport
ASU32_RS07155	COG0395	ABC-type sugar transport system, permease component
ASU32_RS07160	COG0657	acetylesterase activity
ASU32_RS07165	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS07175	COG0579	oxidoreductase
ASU32_RS07185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASU32_RS07190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ASU32_RS07195	COG0366	Alpha amylase catalytic
ASU32_RS07215	COG0477	Major facilitator Superfamily
ASU32_RS07240	COG1929	Belongs to the glycerate kinase type-1 family
ASU32_RS07245	COG3960	tartronate-semialdehyde synthase activity
ASU32_RS07250	COG2084	Dehydrogenase
ASU32_RS07255	COG3622	Belongs to the hyi family
ASU32_RS07260	COG2233	PERMEase
ASU32_RS07270	COG2351	hydroxyisourate hydrolase activity
ASU32_RS07300	COG1335	isochorismatase
ASU32_RS07305	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ASU32_RS07340	COG1234	tRNA 3'-trailer cleavage
ASU32_RS07345	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ASU32_RS07350	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ASU32_RS07355	COG1316	TRANSCRIPTIONal
ASU32_RS07400	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASU32_RS07410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ASU32_RS07415	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ASU32_RS07425	COG0439	Biotin carboxylase
ASU32_RS07435	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS07450	COG0583	DNA-binding transcription factor activity
ASU32_RS07460	COG1376	ErfK ybiS ycfS ynhG family protein
ASU32_RS07495	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS07500	COG3402	PFAM membrane-flanked domain
ASU32_RS07525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASU32_RS07535	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ASU32_RS07540	COG0067	glutamate synthase
ASU32_RS07540	COG0070	glutamate synthase
ASU32_RS07540	COG0069	glutamate synthase activity
ASU32_RS07555	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ASU32_RS07565	COG0433	COG0433 Predicted ATPase
ASU32_RS07575	COG0300	oxidoreductase activity
ASU32_RS07580	COG2259	Doxx family
ASU32_RS07590	COG0446	pyridine nucleotide-disulphide oxidoreductase
ASU32_RS07590	COG1902	pentaerythritol trinitrate reductase activity
ASU32_RS07595	COG1695	Transcriptional regulator
ASU32_RS07620	COG2851	Citrate transporter
ASU32_RS07625	COG3290	protein histidine kinase activity
ASU32_RS07630	COG4565	transcriptional regulatory protein
ASU32_RS07650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASU32_RS07655	COG2151	metal-sulfur cluster biosynthetic enzyme
ASU32_RS07660	COG3396	Phenylacetate-CoA oxygenase
ASU32_RS07665	COG3460	Phenylacetate-CoA oxygenase
ASU32_RS07670	COG3396	Phenylacetate-CoA oxygenase
ASU32_RS07675	COG1024	Enoyl-CoA hydratase
ASU32_RS07690	COG1309	transcriptional regulator
ASU32_RS07695	COG1012	belongs to the aldehyde dehydrogenase family
ASU32_RS07695	COG2030	dehydratase
ASU32_RS07715	COG1012	belongs to the aldehyde dehydrogenase family
ASU32_RS07720	COG3177	Filamentation induced by cAMP protein fic
ASU32_RS07730	COG1131	(ABC) transporter
ASU32_RS07750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS07810	COG2146	nitrite reductase [NAD(P)H] activity
ASU32_RS07810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASU32_RS07815	COG2146	nitrite reductase [NAD(P)H] activity
ASU32_RS07815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ASU32_RS07825	COG0243	molybdopterin cofactor binding
ASU32_RS07865	COG2902	Dehydrogenase
ASU32_RS07870	COG0824	Thioesterase
ASU32_RS07890	COG0366	Alpha amylase catalytic
ASU32_RS07900	COG5001	Diguanylate cyclase
ASU32_RS07920	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ASU32_RS07925	COG3012	SEC-C Motif Domain Protein
ASU32_RS07940	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ASU32_RS07945	COG0501	Belongs to the peptidase M48B family
ASU32_RS07980	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ASU32_RS08000	COG2197	response regulator
ASU32_RS08010	COG2124	cytochrome p450
ASU32_RS08025	COG0531	amino acid
ASU32_RS08035	COG1396	sequence-specific DNA binding
ASU32_RS08045	COG1024	Enoyl-CoA hydratase
ASU32_RS08065	COG0477	Major facilitator Superfamily
ASU32_RS08125	COG0582	viral genome integration into host DNA
ASU32_RS08135	COG0702	epimerase
ASU32_RS08165	COG1396	sequence-specific DNA binding
ASU32_RS08170	COG3135	benzoate transporter
ASU32_RS08175	COG0515	serine threonine protein kinase
ASU32_RS08205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASU32_RS08220	COG0300	oxidoreductase activity
ASU32_RS08245	COG0544	peptidyl-prolyl cis-trans isomerase activity
ASU32_RS08255	COG0740	serine-type endopeptidase activity
ASU32_RS08270	COG0525	valine-tRNA ligase activity
ASU32_RS08275	COG0285	dihydrofolate synthase activity
ASU32_RS08290	COG1530	ribonuclease E activity
ASU32_RS08300	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ASU32_RS08305	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ASU32_RS08310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ASU32_RS08325	COG0740	serine-type endopeptidase activity
ASU32_RS08330	COG0740	serine-type endopeptidase activity
ASU32_RS08350	COG0598	Magnesium transport protein CorA
ASU32_RS08355	COG0477	Major facilitator Superfamily
ASU32_RS08355	COG2814	Major facilitator Superfamily
ASU32_RS08360	COG0477	Major facilitator Superfamily
ASU32_RS08385	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ASU32_RS08400	COG1917	Cupin 2, conserved barrel domain protein
ASU32_RS08410	COG0456	acetyltransferase
ASU32_RS08415	COG4257	antibiotic catabolic process
ASU32_RS08420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASU32_RS08440	COG0477	Major facilitator Superfamily
ASU32_RS08445	COG0742	ribosomal rna small subunit methyltransferase
ASU32_RS08450	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ASU32_RS08455	COG3599	regulation of cell shape
ASU32_RS08465	COG0571	ribonuclease III activity
ASU32_RS08500	COG1254	Belongs to the acylphosphatase family
ASU32_RS08510	COG0754	glutathionylspermidine amidase activity
ASU32_RS08515	COG3766	membrane
ASU32_RS08520	COG1196	nuclear chromosome segregation
ASU32_RS08525	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ASU32_RS08600	COG0831	urea catabolic process
ASU32_RS08605	COG0832	Belongs to the urease beta subunit family
ASU32_RS08610	COG0804	urea catabolic process
ASU32_RS08615	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ASU32_RS08620	COG0830	nickel cation binding
ASU32_RS08625	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ASU32_RS08630	COG0829	nickel cation binding
ASU32_RS08635	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ASU32_RS08645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS08655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASU32_RS08700	COG2267	carboxylic ester hydrolase activity
ASU32_RS08705	COG1021	2,3-dihydroxybenzoate-AMP ligase
ASU32_RS08720	COG3473	Maleate cis-trans isomerase
ASU32_RS08740	COG3795	YCII-related domain
ASU32_RS08745	COG4941	Belongs to the sigma-70 factor family
ASU32_RS08765	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ASU32_RS08790	COG0228	four-way junction DNA binding
ASU32_RS08800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ASU32_RS08805	COG0336	Belongs to the RNA methyltransferase TrmD family
ASU32_RS08845	COG0335	large ribosomal subunit rRNA binding
ASU32_RS08860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ASU32_RS08880	COG0792	nuclease activity
ASU32_RS08910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASU32_RS08915	COG2011	ABC-type metal ion transport system permease component
ASU32_RS08920	COG0477	Major facilitator Superfamily
ASU32_RS08925	COG4974	Belongs to the 'phage' integrase family
ASU32_RS08950	COG0501	Belongs to the peptidase M48B family
ASU32_RS08955	COG2814	Major facilitator Superfamily
ASU32_RS08965	COG0443	Heat shock 70 kDa protein
ASU32_RS08975	COG1823	symporter activity
ASU32_RS08985	COG2272	Belongs to the type-B carboxylesterase lipase family
ASU32_RS08995	COG1115	amino acid carrier protein
ASU32_RS09000	COG0052	Belongs to the universal ribosomal protein uS2 family
ASU32_RS09005	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ASU32_RS09025	COG0528	UMP kinase activity
ASU32_RS09030	COG0233	cytoplasmic translational termination
ASU32_RS09035	COG0575	Belongs to the CDS family
ASU32_RS09050	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ASU32_RS09075	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ASU32_RS09080	COG0750	zinc metalloprotease
ASU32_RS09085	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ASU32_RS09100	COG2957	Belongs to the agmatine deiminase family
ASU32_RS09125	COG0183	Belongs to the thiolase family
ASU32_RS09130	COG0768	penicillin binding
ASU32_RS09165	COG0579	oxidoreductase
ASU32_RS09195	COG1648	precorrin-2 dehydrogenase activity
ASU32_RS09195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ASU32_RS09210	COG3022	response to hydroperoxide
ASU32_RS09235	COG0779	Required for maturation of 30S ribosomal subunits
ASU32_RS09260	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ASU32_RS09265	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ASU32_RS09270	COG0534	Mate efflux family protein
ASU32_RS09305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASU32_RS09310	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ASU32_RS09320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ASU32_RS09335	COG4607	ABC-type enterochelin transport system periplasmic component
ASU32_RS09355	COG1309	transcriptional regulator
ASU32_RS09360	COG1321	iron dependent repressor
ASU32_RS09370	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ASU32_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS09390	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ASU32_RS09390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ASU32_RS09395	COG1185	polyribonucleotide nucleotidyltransferase activity
ASU32_RS09410	COG0596	Alpha beta hydrolase
ASU32_RS09415	COG0584	glycerophosphoryl diester phosphodiesterase
ASU32_RS09430	COG0686	Belongs to the AlaDH PNT family
ASU32_RS09435	COG1522	sequence-specific DNA binding
ASU32_RS09440	COG1063	alcohol dehydrogenase
ASU32_RS09445	COG1741	Belongs to the pirin family
ASU32_RS09465	COG2409	Drug exporters of the RND superfamily
ASU32_RS09500	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ASU32_RS09510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASU32_RS09515	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ASU32_RS09565	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ASU32_RS09575	COG1058	Belongs to the CinA family
ASU32_RS09575	COG1546	Belongs to the CinA family
ASU32_RS09580	COG1396	sequence-specific DNA binding
ASU32_RS09585	COG1842	Phage shock protein A
ASU32_RS09620	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ASU32_RS09625	COG2137	regulation of response to DNA damage stimulus
ASU32_RS09635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASU32_RS09640	COG0765	amino acid transport
ASU32_RS09645	COG0765	amino acid transport
ASU32_RS09650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASU32_RS09655	COG1126	abc transporter atp-binding protein
ASU32_RS09660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ASU32_RS09670	COG1196	nuclear chromosome segregation
ASU32_RS09680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ASU32_RS09685	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ASU32_RS09690	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ASU32_RS09705	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS09710	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS09725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ASU32_RS09740	COG1643	Atp-dependent helicase
ASU32_RS09755	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ASU32_RS09760	COG1595	DNA-templated transcription, initiation
ASU32_RS09790	COG1335	isochorismatase
ASU32_RS09835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASU32_RS09860	COG0123	including yeast histone deacetylase and acetoin utilization protein
ASU32_RS09875	COG2890	protein-(glutamine-N5) methyltransferase activity
ASU32_RS09910	COG3590	peptidase
ASU32_RS09930	COG0183	Belongs to the thiolase family
ASU32_RS09935	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS09950	COG1011	Hydrolase
ASU32_RS09975	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS09980	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS09990	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS09995	COG2267	carboxylic ester hydrolase activity
ASU32_RS10010	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS10015	COG4770	biotin carboxylase activity
ASU32_RS10075	COG0756	dUTP diphosphatase activity
ASU32_RS10095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ASU32_RS10100	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ASU32_RS10115	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ASU32_RS10125	COG3253	May function as heme-dependent peroxidase
ASU32_RS10130	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASU32_RS10145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASU32_RS10145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ASU32_RS10155	COG1937	Protein conserved in bacteria
ASU32_RS10185	COG0706	membrane insertase activity
ASU32_RS10200	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS10200	COG0604	alcohol dehydrogenase
ASU32_RS10200	COG3321	synthase
ASU32_RS10240	COG2814	Major facilitator Superfamily
ASU32_RS10260	COG1940	carbohydrate kinase activity
ASU32_RS10265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ASU32_RS10290	COG2814	Major facilitator Superfamily
ASU32_RS10320	COG0346	lactoylglutathione lyase activity
ASU32_RS10350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ASU32_RS10365	COG1560	Kdo2-lipid A biosynthetic process
ASU32_RS10370	COG0438	transferase activity, transferring glycosyl groups
ASU32_RS10375	COG1051	belongs to the nudix hydrolase family
ASU32_RS10395	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ASU32_RS10410	COG1946	Acyl-CoA thioesterase
ASU32_RS10415	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ASU32_RS10425	COG0217	transcriptional regulatory protein
ASU32_RS10435	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ASU32_RS10440	COG0632	four-way junction helicase activity
ASU32_RS10445	COG2255	four-way junction helicase activity
ASU32_RS10450	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS10455	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ASU32_RS10475	COG2175	clavaminate synthase activity
ASU32_RS10480	COG3246	L-lysine catabolic process to acetate
ASU32_RS10500	COG0514	ATP-dependent DNA helicase (RecQ)
ASU32_RS10515	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ASU32_RS10525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ASU32_RS10540	COG0124	histidyl-tRNA synthetase
ASU32_RS10555	COG0640	Transcriptional regulator
ASU32_RS10565	COG0523	cobalamin synthesis protein
ASU32_RS10580	COG0277	FAD linked oxidase domain protein
ASU32_RS10590	COG0477	Major facilitator Superfamily
ASU32_RS10595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS10605	COG2814	Major facilitator Superfamily
ASU32_RS10630	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ASU32_RS10660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ASU32_RS10670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ASU32_RS10690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS10695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS10700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS10705	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS10715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASU32_RS10720	COG1126	abc transporter atp-binding protein
ASU32_RS10725	COG0765	amino acid transport
ASU32_RS10730	COG2197	response regulator
ASU32_RS10735	COG4585	Histidine kinase
ASU32_RS10775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS10780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS10800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ASU32_RS10810	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ASU32_RS10820	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ASU32_RS10855	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ASU32_RS10880	COG0745	RESPONSE REGULATOR receiver
ASU32_RS10885	COG5002	protein histidine kinase activity
ASU32_RS10915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ASU32_RS10920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASU32_RS10925	COG0131	Imidazoleglycerol-phosphate dehydratase
ASU32_RS10935	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ASU32_RS10940	COG1953	Uracil, thiamine, allantoin
ASU32_RS10950	COG1301	dicarboxylic acid transport
ASU32_RS10955	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ASU32_RS10960	COG3257	ureidoglycine aminohydrolase activity
ASU32_RS10970	COG0402	S-adenosylhomocysteine deaminase activity
ASU32_RS10980	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ASU32_RS10990	COG2252	PERMEase
ASU32_RS10995	COG1414	Transcriptional regulator
ASU32_RS11020	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ASU32_RS11030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ASU32_RS11035	COG0483	inositol monophosphate 1-phosphatase activity
ASU32_RS11040	COG0107	imidazoleglycerol-phosphate synthase activity
ASU32_RS11045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ASU32_RS11060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ASU32_RS11070	COG0134	indole-3-glycerol-phosphate synthase activity
ASU32_RS11075	COG2971	BadF BadG BcrA BcrD
ASU32_RS11080	COG2814	Major facilitator Superfamily
ASU32_RS11085	COG2188	Transcriptional regulator
ASU32_RS11095	COG1126	abc transporter atp-binding protein
ASU32_RS11100	COG0765	amino acid transport
ASU32_RS11115	COG0159	tryptophan synthase activity
ASU32_RS11120	COG3706	GGDEF domain
ASU32_RS11135	COG0488	(ABC) transporter
ASU32_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS11160	COG1309	transcriptional regulator
ASU32_RS11165	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ASU32_RS11170	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS11200	COG0584	glycerophosphoryl diester phosphodiesterase
ASU32_RS11220	COG1309	transcriptional regulator
ASU32_RS11225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ASU32_RS11235	COG0791	NLP P60 protein
ASU32_RS11235	COG3883	PFAM NLP P60 protein
ASU32_RS11240	COG0714	Associated with various cellular activities
ASU32_RS11260	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ASU32_RS11265	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ASU32_RS11365	COG2188	Transcriptional regulator
ASU32_RS11410	COG0028	Belongs to the TPP enzyme family
ASU32_RS11420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ASU32_RS11430	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ASU32_RS11440	COG5001	Diguanylate cyclase
ASU32_RS11450	COG0531	amino acid
ASU32_RS11475	COG1487	ribonuclease activity
ASU32_RS11510	COG3265	gluconokinase activity
ASU32_RS11545	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ASU32_RS11570	COG1968	undecaprenyl-diphosphatase activity
ASU32_RS11575	COG0583	DNA-binding transcription factor activity
ASU32_RS11580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASU32_RS11615	COG3220	belongs to the UPF0276 family
ASU32_RS11630	COG0215	cysteine-tRNA ligase activity
ASU32_RS11645	COG0646	methionine synthase
ASU32_RS11645	COG1410	methionine synthase
ASU32_RS11655	COG5504	Zn-dependent protease
ASU32_RS11665	COG0546	phosphoglycolate phosphatase activity
ASU32_RS11680	COG0140	phosphoribosyl-ATP diphosphatase activity
ASU32_RS11685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ASU32_RS11700	COG1222	aaa ATPase
ASU32_RS11705	COG1131	(ABC) transporter
ASU32_RS11705	COG1716	ATPase activity
ASU32_RS11705	COG0842	Transport permease protein
ASU32_RS11730	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ASU32_RS11735	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ASU32_RS11745	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS11765	COG2378	regulation of single-species biofilm formation
ASU32_RS11800	COG0477	Major facilitator Superfamily
ASU32_RS11810	COG0300	oxidoreductase activity
ASU32_RS11845	COG3467	pyridoxamine 5'-phosphate
ASU32_RS11850	COG2814	Major facilitator Superfamily
ASU32_RS11855	COG0657	acetylesterase activity
ASU32_RS11900	COG1556	Lactate utilization protein
ASU32_RS11905	COG1139	Iron-sulfur cluster binding protein
ASU32_RS11910	COG0247	lactate metabolic process
ASU32_RS11930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ASU32_RS11940	COG0463	Glycosyl transferase, family 2
ASU32_RS11960	COG1376	ErfK ybiS ycfS ynhG family protein
ASU32_RS11965	COG2072	flavoprotein involved in K transport
ASU32_RS11990	COG1454	alcohol dehydrogenase
ASU32_RS12010	COG2186	Transcriptional regulator
ASU32_RS12015	COG2807	transmembrane transport
ASU32_RS12025	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ASU32_RS12080	COG1280	lysine exporter protein (LysE YggA)
ASU32_RS12095	COG2072	flavoprotein involved in K transport
ASU32_RS12100	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS12105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ASU32_RS12110	COG0798	PFAM Bile acid sodium symporter
ASU32_RS12145	COG1984	allophanate hydrolase subunit 2
ASU32_RS12150	COG0477	Major facilitator Superfamily
ASU32_RS12155	COG2186	Transcriptional regulator
ASU32_RS12165	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASU32_RS12170	COG1280	lysine exporter protein (LysE YggA)
ASU32_RS12200	COG2354	Protein conserved in bacteria
ASU32_RS12245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ASU32_RS12250	COG0736	holo-[acyl-carrier-protein] synthase activity
ASU32_RS12265	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ASU32_RS12270	COG0438	transferase activity, transferring glycosyl groups
ASU32_RS12315	COG1063	alcohol dehydrogenase
ASU32_RS12325	COG1464	Belongs to the NlpA lipoprotein family
ASU32_RS12365	COG2268	Band 7 protein
ASU32_RS12375	COG0477	Major facilitator Superfamily
ASU32_RS12405	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ASU32_RS12410	COG1074	ATP-dependent DNA helicase activity
ASU32_RS12435	COG4762	Protein conserved in bacteria
ASU32_RS12445	COG0725	ABC transporter, periplasmic molybdate-binding protein
ASU32_RS12520	COG1253	flavin adenine dinucleotide binding
ASU32_RS12535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASU32_RS12540	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ASU32_RS12565	COG4615	Cyclic peptide transporter
ASU32_RS12600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ASU32_RS12600	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASU32_RS12610	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASU32_RS12610	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ASU32_RS12635	COG1716	ATPase activity
ASU32_RS12650	COG0653	protein targeting
ASU32_RS12655	COG2234	aminopeptidase activity
ASU32_RS12665	COG0596	Alpha beta hydrolase
ASU32_RS12685	COG2249	NAD(P)H dehydrogenase (quinone) activity
ASU32_RS12705	COG2365	Tyrosine phosphatase family
ASU32_RS12735	COG1160	GTP binding
ASU32_RS12740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ASU32_RS12755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ASU32_RS12760	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ASU32_RS12775	COG0494	nUDIX hydrolase
ASU32_RS12780	COG0504	CTP synthase activity
ASU32_RS12800	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ASU32_RS12815	COG0647	UMP catabolic process
ASU32_RS12840	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ASU32_RS12855	COG2835	tetraacyldisaccharide 4'-kinase activity
ASU32_RS12870	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS12880	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS12885	COG1131	(ABC) transporter
ASU32_RS12895	COG1309	transcriptional regulator
ASU32_RS12900	COG0165	Argininosuccinate lyase
ASU32_RS12905	COG0137	argininosuccinate synthase activity
ASU32_RS12920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ASU32_RS12925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ASU32_RS12930	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ASU32_RS12950	COG1309	transcriptional regulator
ASU32_RS12985	COG0492	ferredoxin-NADP+ reductase activity
ASU32_RS13000	COG0477	Major facilitator Superfamily
ASU32_RS13005	COG0072	phenylalanine-tRNA ligase activity
ASU32_RS13005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ASU32_RS13010	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ASU32_RS13045	COG2233	PERMEase
ASU32_RS13060	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ASU32_RS13065	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ASU32_RS13105	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS13115	COG0477	Major facilitator Superfamily
ASU32_RS13170	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASU32_RS13190	COG0596	Alpha beta hydrolase
ASU32_RS13215	COG3973	AAA domain
ASU32_RS13245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ASU32_RS13255	COG0237	dephospho-CoA kinase activity
ASU32_RS13255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ASU32_RS13265	COG1070	Carbohydrate kinase
ASU32_RS13275	COG1063	alcohol dehydrogenase
ASU32_RS13295	COG0395	ABC-type sugar transport system, permease component
ASU32_RS13300	COG3842	ATPase activity
ASU32_RS13370	COG4260	virion core protein, lumpy skin disease virus
ASU32_RS13375	COG3422	double-strand break repair
ASU32_RS13400	COG0477	Major facilitator Superfamily
ASU32_RS13415	COG0596	Alpha beta hydrolase
ASU32_RS13425	COG1902	pentaerythritol trinitrate reductase activity
ASU32_RS13430	COG0435	Glutathione S-transferase
ASU32_RS13460	COG4303	Ethanolamine ammonia lyase large subunit
ASU32_RS13470	COG0531	amino acid
ASU32_RS13535	COG0346	lactoylglutathione lyase activity
ASU32_RS13540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ASU32_RS13640	COG4974	Belongs to the 'phage' integrase family
ASU32_RS13650	COG3243	poly(R)-hydroxyalkanoic acid synthase
ASU32_RS13670	COG0705	Rhomboid family
ASU32_RS13670	COG0457	Tetratricopeptide repeat
ASU32_RS13680	COG1946	Acyl-CoA thioesterase
ASU32_RS13690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ASU32_RS13715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ASU32_RS13725	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS13740	COG0667	Aldo Keto reductase
ASU32_RS13750	COG2188	Transcriptional regulator
ASU32_RS13765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASU32_RS13785	COG2151	metal-sulfur cluster biosynthetic enzyme
ASU32_RS13800	COG0396	ATPase activity
ASU32_RS13825	COG1131	(ABC) transporter
ASU32_RS13855	COG1309	transcriptional regulator
ASU32_RS13865	COG0109	protoheme IX farnesyltransferase activity
ASU32_RS13875	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ASU32_RS13915	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS13925	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
ASU32_RS13930	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ASU32_RS13935	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ASU32_RS13940	COG0149	triose-phosphate isomerase activity
ASU32_RS13945	COG0126	phosphoglycerate kinase activity
ASU32_RS13950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASU32_RS13955	COG1481	regulation of sporulation
ASU32_RS13960	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ASU32_RS13965	COG1660	Displays ATPase and GTPase activities
ASU32_RS13975	COG0405	Gamma-glutamyltransferase
ASU32_RS13985	COG3842	ATPase activity
ASU32_RS14005	COG0322	excinuclease ABC activity
ASU32_RS14020	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS14060	COG3104	oligopeptide transport
ASU32_RS14085	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ASU32_RS14090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASU32_RS14090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASU32_RS14125	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASU32_RS14130	COG0242	peptide deformylase activity
ASU32_RS14140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ASU32_RS14145	COG1522	sequence-specific DNA binding
ASU32_RS14160	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASU32_RS14190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ASU32_RS14200	COG1758	RNA polymerase activity
ASU32_RS14215	COG0475	glutathione-regulated potassium exporter activity
ASU32_RS14225	COG0284	orotidine-5'-phosphate decarboxylase activity
ASU32_RS14235	COG0505	Belongs to the CarA family
ASU32_RS14255	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ASU32_RS14270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ASU32_RS14275	COG0006	proline dipeptidase activity
ASU32_RS14315	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ASU32_RS14320	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ASU32_RS14330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ASU32_RS14335	COG1193	negative regulation of DNA recombination
ASU32_RS14385	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ASU32_RS14400	COG0252	asparaginase activity
ASU32_RS14405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ASU32_RS14410	COG0569	domain protein
ASU32_RS14435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ASU32_RS14465	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ASU32_RS14470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ASU32_RS14475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ASU32_RS14490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASU32_RS14495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ASU32_RS14500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ASU32_RS14510	COG0768	penicillin binding
ASU32_RS14520	COG0275	rRNA processing
ASU32_RS14525	COG2001	Belongs to the MraZ family
ASU32_RS14555	COG2072	flavoprotein involved in K transport
ASU32_RS14570	COG0142	geranyltranstransferase activity
ASU32_RS14575	COG4607	ABC-type enterochelin transport system periplasmic component
ASU32_RS14590	COG4604	ABC transporter, ATP-binding protein
ASU32_RS14615	COG2357	RelA SpoT domain protein
ASU32_RS14635	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ASU32_RS14650	COG1940	carbohydrate kinase activity
ASU32_RS14680	COG0438	transferase activity, transferring glycosyl groups
ASU32_RS14725	COG0442	prolyl-tRNA aminoacylation
ASU32_RS14730	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ASU32_RS14740	COG1845	cytochrome c oxidase, subunit III
ASU32_RS14745	COG2010	Cytochrome c
ASU32_RS14775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ASU32_RS14800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ASU32_RS14820	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ASU32_RS14840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASU32_RS14845	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ASU32_RS14850	COG2233	PERMEase
ASU32_RS14870	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ASU32_RS14875	COG0508	dehydrogenase complex catalyzes the overall conversion of
ASU32_RS14885	COG0321	lipoyl(octanoyl) transferase activity
ASU32_RS14910	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ASU32_RS14925	COG0174	glutamine synthetase
ASU32_RS14955	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ASU32_RS14960	COG0174	glutamine synthetase
ASU32_RS14975	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ASU32_RS14975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASU32_RS14980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ASU32_RS15000	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
ASU32_RS15080	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASU32_RS15110	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ASU32_RS15125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ASU32_RS15225	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ASU32_RS15235	COG0358	DNA primase activity
ASU32_RS15240	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ASU32_RS15245	COG1278	Cold shock
ASU32_RS15255	COG0423	glycine-tRNA ligase activity
ASU32_RS15290	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ASU32_RS15295	COG1846	Transcriptional regulator
ASU32_RS15300	COG1764	response to oxidative stress
ASU32_RS15315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ASU32_RS15320	COG1381	Involved in DNA repair and RecF pathway recombination
ASU32_RS15360	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ASU32_RS15380	COG0484	heat shock protein binding
ASU32_RS15385	COG1420	regulation of RNA biosynthetic process
ASU32_RS15415	COG0175	sulfate reduction
ASU32_RS15430	COG4552	Acetyltransferase involved in intracellular survival and related
ASU32_RS15435	COG3842	ATPase activity
ASU32_RS15440	COG4208	sulfate ABC transporter
ASU32_RS15445	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ASU32_RS15460	COG3387	PFAM Glycoside hydrolase 15-related
ASU32_RS15485	COG1733	regulation of RNA biosynthetic process
ASU32_RS15495	COG0339	signal peptide processing
ASU32_RS15520	COG2070	2-Nitropropane dioxygenase
ASU32_RS15545	COG2814	Major facilitator Superfamily
ASU32_RS15550	COG0656	L-ascorbic acid biosynthetic process
ASU32_RS15555	COG0481	GTPase activity
ASU32_RS15565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASU32_RS15570	COG1012	belongs to the aldehyde dehydrogenase family
ASU32_RS15605	COG1305	Transglutaminase-like
ASU32_RS15620	COG0268	Binds directly to 16S ribosomal RNA
ASU32_RS15635	COG1596	polysaccharide export
ASU32_RS15635	COG1555	photosystem II stabilization
ASU32_RS15640	COG1307	EDD domain protein, DegV family
ASU32_RS15645	COG2755	lipolytic protein G-D-S-L family
ASU32_RS15650	COG0406	alpha-ribazole phosphatase activity
ASU32_RS15655	COG0799	negative regulation of ribosome biogenesis
ASU32_RS15660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ASU32_RS15685	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ASU32_RS15710	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS15715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASU32_RS15730	COG1024	Enoyl-CoA hydratase
ASU32_RS15735	COG1309	transcriptional regulator
ASU32_RS15740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ASU32_RS15745	COG1461	Dihydroxyacetone kinase
ASU32_RS15750	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ASU32_RS15770	COG1181	Belongs to the D-alanine--D-alanine ligase family
ASU32_RS15775	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ASU32_RS15780	COG1920	GTP binding
ASU32_RS15785	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ASU32_RS15800	COG0066	3-isopropylmalate dehydratase activity
ASU32_RS15805	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ASU32_RS15820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASU32_RS15830	COG1846	Transcriptional regulator
ASU32_RS15880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASU32_RS15885	COG1082	Xylose isomerase domain protein TIM barrel
ASU32_RS15890	COG0673	inositol 2-dehydrogenase activity
ASU32_RS15900	COG3962	Belongs to the TPP enzyme family
ASU32_RS15905	COG3718	enzyme involved in inositol metabolism
ASU32_RS15925	COG2188	Transcriptional regulator
ASU32_RS15940	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS15945	COG0477	Major facilitator Superfamily
ASU32_RS15955	COG0673	inositol 2-dehydrogenase activity
ASU32_RS15960	COG1082	Xylose isomerase domain protein TIM barrel
ASU32_RS15965	COG0673	inositol 2-dehydrogenase activity
ASU32_RS15970	COG0673	inositol 2-dehydrogenase activity
ASU32_RS15980	COG1172	Belongs to the binding-protein-dependent transport system permease family
ASU32_RS15990	COG1609	Transcriptional regulator
ASU32_RS15995	COG0673	inositol 2-dehydrogenase activity
ASU32_RS16005	COG0673	inositol 2-dehydrogenase activity
ASU32_RS16010	COG2814	Major facilitator Superfamily
ASU32_RS16015	COG0589	response to stress
ASU32_RS16020	COG0179	Fumarylacetoacetate (FAA) hydrolase
ASU32_RS16025	COG2271	Major facilitator Superfamily
ASU32_RS16030	COG0473	3-isopropylmalate dehydrogenase activity
ASU32_RS16045	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS16080	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ASU32_RS16085	COG0440	acetolactate synthase activity
ASU32_RS16100	COG0129	dihydroxy-acid dehydratase activity
ASU32_RS16115	COG2199	diguanylate cyclase activity
ASU32_RS16120	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ASU32_RS16130	COG0205	6-phosphofructokinase activity
ASU32_RS16135	COG2197	response regulator
ASU32_RS16140	COG4585	Histidine kinase
ASU32_RS16150	COG1959	2 iron, 2 sulfur cluster binding
ASU32_RS16155	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASU32_RS16165	COG0154	amidase activity
ASU32_RS16180	COG1733	regulation of RNA biosynthetic process
ASU32_RS16190	COG1012	belongs to the aldehyde dehydrogenase family
ASU32_RS16200	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS16205	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ASU32_RS16230	COG2072	flavoprotein involved in K transport
ASU32_RS16235	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ASU32_RS16245	COG1231	oxidoreductase activity
ASU32_RS16290	COG1228	amidohydrolase
ASU32_RS16295	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ASU32_RS16310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ASU32_RS16350	COG0482	sulfurtransferase activity
ASU32_RS16410	COG2132	Multicopper oxidase
ASU32_RS16415	COG4585	Histidine kinase
ASU32_RS16420	COG2197	response regulator
ASU32_RS16430	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ASU32_RS16440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ASU32_RS16465	COG0110	maltose O-acetyltransferase activity
ASU32_RS16490	COG0024	Methionine aminopeptidase
ASU32_RS16510	COG1012	belongs to the aldehyde dehydrogenase family
ASU32_RS16520	COG0436	Aminotransferase
ASU32_RS16530	COG2226	methyltransferase
ASU32_RS16545	COG1119	ATPase activity
ASU32_RS16550	COG1523	belongs to the glycosyl hydrolase 13 family
ASU32_RS16555	COG0560	Phosphoserine phosphatase
ASU32_RS16555	COG3830	Belongs to the UPF0237 family
ASU32_RS16585	COG3813	Protein conserved in bacteria
ASU32_RS16595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASU32_RS16670	COG0243	molybdopterin cofactor binding
ASU32_RS16690	COG1982	Orn Lys Arg decarboxylase major
ASU32_RS16740	COG0753	catalase activity
ASU32_RS16775	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS16800	COG2890	protein-(glutamine-N5) methyltransferase activity
ASU32_RS16810	COG0783	Belongs to the Dps family
ASU32_RS16815	COG0655	NAD(P)H dehydrogenase (quinone) activity
ASU32_RS16820	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASU32_RS16825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASU32_RS16875	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ASU32_RS16915	COG1054	Belongs to the UPF0176 family
ASU32_RS16925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASU32_RS16930	COG1116	anion transmembrane transporter activity
ASU32_RS16950	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ASU32_RS16965	COG0346	lactoylglutathione lyase activity
ASU32_RS16980	COG1733	regulation of RNA biosynthetic process
ASU32_RS16985	COG0640	Transcriptional regulator
ASU32_RS17015	COG2186	Transcriptional regulator
ASU32_RS17050	COG0033	Phosphoglucomutase
ASU32_RS17055	COG2610	gluconate transmembrane transporter activity
ASU32_RS17060	COG0800	Aldolase
ASU32_RS17065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ASU32_RS17100	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ASU32_RS17115	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ASU32_RS17120	COG2177	Part of the ABC transporter FtsEX involved in
ASU32_RS17125	COG2884	Cell division ATP-binding protein ftsE
ASU32_RS17135	COG0668	transmembrane transport
ASU32_RS17140	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ASU32_RS17155	COG0483	inositol monophosphate 1-phosphatase activity
ASU32_RS17160	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS17165	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS17175	COG2197	response regulator
ASU32_RS17180	COG2409	Drug exporters of the RND superfamily
ASU32_RS17190	COG1388	LysM domain
ASU32_RS17195	COG2814	Major facilitator Superfamily
ASU32_RS17205	COG0730	response to heat
ASU32_RS17215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS17230	COG1615	UPF0182 protein
ASU32_RS17240	COG3480	Lon protease (S16) C-terminal proteolytic domain
ASU32_RS17275	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS17320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS17325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ASU32_RS17345	COG0596	Alpha beta hydrolase
ASU32_RS17390	COG0596	Alpha beta hydrolase
ASU32_RS17395	COG1309	transcriptional regulator
ASU32_RS17405	COG0513	Belongs to the DEAD box helicase family
ASU32_RS17425	COG1192	Involved in chromosome partitioning
ASU32_RS17430	COG0406	alpha-ribazole phosphatase activity
ASU32_RS17440	COG1597	lipid kinase activity
ASU32_RS17460	COG1595	DNA-templated transcription, initiation
ASU32_RS17470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ASU32_RS17490	COG1012	belongs to the aldehyde dehydrogenase family
ASU32_RS17505	COG2135	peptidase activity
ASU32_RS17520	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ASU32_RS17525	COG1162	GTPase activity
ASU32_RS17530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ASU32_RS17605	COG0653	protein targeting
ASU32_RS17610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ASU32_RS17625	COG1040	competence protein
ASU32_RS17635	COG5002	protein histidine kinase activity
ASU32_RS17640	COG0745	RESPONSE REGULATOR receiver
ASU32_RS17660	COG0454	-acetyltransferase
ASU32_RS17660	COG0456	acetyltransferase
ASU32_RS17665	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ASU32_RS17670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ASU32_RS17675	COG5662	AntiSigma factor
ASU32_RS17680	COG1595	DNA-templated transcription, initiation
ASU32_RS17685	COG4122	O-methyltransferase activity
ASU32_RS17695	COG2755	lipolytic protein G-D-S-L family
ASU32_RS17700	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ASU32_RS17715	COG1316	TRANSCRIPTIONal
ASU32_RS17755	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ASU32_RS17765	COG2205	protein histidine kinase activity
ASU32_RS17770	COG0745	RESPONSE REGULATOR receiver
ASU32_RS17780	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ASU32_RS17780	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ASU32_RS17785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ASU32_RS17795	COG0424	maF-like protein
ASU32_RS17800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASU32_RS17845	COG4770	biotin carboxylase activity
ASU32_RS17860	COG1396	sequence-specific DNA binding
ASU32_RS17865	COG0431	NADPH-dependent FMN reductase
ASU32_RS17895	COG4585	Histidine kinase
ASU32_RS17915	COG2272	Belongs to the type-B carboxylesterase lipase family
ASU32_RS17920	COG1201	RNA secondary structure unwinding
ASU32_RS17925	COG1414	Transcriptional regulator
ASU32_RS17935	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS17945	COG3360	Dodecin
ASU32_RS17955	COG0477	Major facilitator Superfamily
ASU32_RS17965	COG2197	response regulator
ASU32_RS17980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ASU32_RS17985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASU32_RS17990	COG0148	phosphopyruvate hydratase activity
ASU32_RS17995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ASU32_RS18010	COG2390	Transcriptional regulator
ASU32_RS18015	COG0205	6-phosphofructokinase activity
ASU32_RS18035	COG1349	DNA-binding transcription factor activity
ASU32_RS18070	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS18080	COG1473	amidohydrolase
ASU32_RS18080	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ASU32_RS18085	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ASU32_RS18085	COG1473	amidohydrolase
ASU32_RS18100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASU32_RS18135	COG2197	response regulator
ASU32_RS18145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ASU32_RS18160	COG2009	succinate dehydrogenase
ASU32_RS18175	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ASU32_RS18225	COG1686	Belongs to the peptidase S11 family
ASU32_RS18235	COG1295	ribonuclease BN
ASU32_RS18240	COG0180	Tryptophanyl-tRNA synthetase
ASU32_RS18245	COG0708	Exodeoxyribonuclease III
ASU32_RS18260	COG2814	Major facilitator Superfamily
ASU32_RS18280	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ASU32_RS18290	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ASU32_RS18305	COG1872	DUF167
ASU32_RS18340	COG0587	DNA-directed DNA polymerase activity
ASU32_RS18375	COG0833	amino acid
ASU32_RS18390	COG2197	response regulator
ASU32_RS18410	COG0702	epimerase
ASU32_RS18415	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ASU32_RS18415	COG0519	Catalyzes the synthesis of GMP from XMP
ASU32_RS18435	COG0516	GMP reductase activity
ASU32_RS18470	COG0459	protein refolding
ASU32_RS18475	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ASU32_RS18530	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ASU32_RS18535	COG0456	acetyltransferase
ASU32_RS18565	COG2154	pterin-4-alpha-carbinolamine dehydratase
ASU32_RS18580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ASU32_RS18610	COG0546	phosphoglycolate phosphatase activity
ASU32_RS18615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ASU32_RS18625	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ASU32_RS18650	COG1674	ftsk spoiiie
ASU32_RS18660	COG1404	Belongs to the peptidase S8 family
ASU32_RS18665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ASU32_RS18755	COG2807	transmembrane transport
ASU32_RS18790	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS18795	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASU32_RS18795	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ASU32_RS18815	COG1024	Enoyl-CoA hydratase
ASU32_RS18820	COG1024	Enoyl-CoA hydratase
ASU32_RS18825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS18830	COG0477	Major facilitator Superfamily
ASU32_RS18835	COG1309	transcriptional regulator
ASU32_RS18850	COG1522	sequence-specific DNA binding
ASU32_RS18925	COG0667	Aldo Keto reductase
ASU32_RS18930	COG1309	transcriptional regulator
ASU32_RS18955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASU32_RS18960	COG1335	isochorismatase
ASU32_RS18965	COG3629	intracellular signal transduction
ASU32_RS18980	COG2801	Transposase and inactivated derivatives
ASU32_RS18985	COG2801	Transposase and inactivated derivatives
ASU32_RS19000	COG0583	DNA-binding transcription factor activity
ASU32_RS19005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ASU32_RS19010	COG0531	amino acid
ASU32_RS19060	COG0604	alcohol dehydrogenase
ASU32_RS19075	COG2267	carboxylic ester hydrolase activity
ASU32_RS19080	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS19100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASU32_RS19105	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS19155	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ASU32_RS19160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ASU32_RS19165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ASU32_RS19175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ASU32_RS19180	COG0583	DNA-binding transcription factor activity
ASU32_RS19190	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ASU32_RS19195	COG2814	Major facilitator Superfamily
ASU32_RS19195	COG0477	Major facilitator Superfamily
ASU32_RS19215	COG1012	belongs to the aldehyde dehydrogenase family
ASU32_RS19220	COG2301	Belongs to the HpcH HpaI aldolase family
ASU32_RS19225	COG2030	dehydratase
ASU32_RS19230	COG1414	Transcriptional regulator
ASU32_RS19260	COG0596	Alpha beta hydrolase
ASU32_RS19275	COG2409	Drug exporters of the RND superfamily
ASU32_RS19285	COG0477	Major facilitator Superfamily
ASU32_RS19290	COG3634	alkyl hydroperoxide reductase activity
ASU32_RS19305	COG1733	regulation of RNA biosynthetic process
ASU32_RS19335	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ASU32_RS19355	COG0659	secondary active sulfate transmembrane transporter activity
ASU32_RS19415	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ASU32_RS19500	COG0101	tRNA pseudouridine synthase activity
ASU32_RS19505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASU32_RS19520	COG0203	ribosomal protein L17
ASU32_RS19525	COG0202	RNA polymerase activity
ASU32_RS19530	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ASU32_RS19535	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ASU32_RS19540	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ASU32_RS19545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ASU32_RS19555	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ASU32_RS19560	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ASU32_RS19595	COG0789	Transcriptional regulator
ASU32_RS19605	COG0563	adenylate kinase activity
ASU32_RS19615	COG0200	Binds to the 23S rRNA
ASU32_RS19620	COG1841	ribosomal large subunit assembly
ASU32_RS19630	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ASU32_RS19635	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ASU32_RS19640	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ASU32_RS19680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ASU32_RS19685	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ASU32_RS19690	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ASU32_RS19725	COG0513	Belongs to the DEAD box helicase family
ASU32_RS19740	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ASU32_RS19745	COG0255	Belongs to the universal ribosomal protein uL29 family
ASU32_RS19750	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ASU32_RS19755	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ASU32_RS19765	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ASU32_RS19770	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ASU32_RS19775	COG0089	rRNA binding
ASU32_RS19780	COG0088	Forms part of the polypeptide exit tunnel
ASU32_RS19785	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ASU32_RS19790	COG0051	transcription antitermination factor activity, RNA binding
ASU32_RS19815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ASU32_RS19865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ASU32_RS19870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ASU32_RS19875	COG0049	tRNA binding
ASU32_RS19880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ASU32_RS19900	COG1131	(ABC) transporter
ASU32_RS19930	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ASU32_RS19940	COG2072	flavoprotein involved in K transport
ASU32_RS19955	COG0657	acetylesterase activity
ASU32_RS19960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASU32_RS20000	COG1595	DNA-templated transcription, initiation
ASU32_RS20010	COG0640	Transcriptional regulator
ASU32_RS20040	COG0438	transferase activity, transferring glycosyl groups
ASU32_RS20045	COG3842	ATPase activity
ASU32_RS20050	COG1653	transport
ASU32_RS20060	COG4209	transmembrane transport
ASU32_RS20085	COG2197	response regulator
ASU32_RS20110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ASU32_RS20130	COG0456	acetyltransferase
ASU32_RS20135	COG0745	RESPONSE REGULATOR receiver
ASU32_RS20145	COG2897	thiosulfate sulfurtransferase activity
ASU32_RS20155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ASU32_RS20170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASU32_RS20180	COG3145	DNA-N1-methyladenine dioxygenase activity
ASU32_RS20215	COG4044	May play a role in the intracellular transport of hydrophobic ligands
ASU32_RS20225	COG1131	(ABC) transporter
ASU32_RS20250	COG0300	oxidoreductase activity
ASU32_RS20255	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ASU32_RS20260	COG4988	ABC transporter
ASU32_RS20265	COG1294	oxidase, subunit
ASU32_RS20270	COG1271	oxidase subunit
ASU32_RS20280	COG1113	amino acid transport
ASU32_RS20285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ASU32_RS20290	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ASU32_RS20305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ASU32_RS20320	COG1609	Transcriptional regulator
ASU32_RS20330	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ASU32_RS20355	COG1090	epimerase
ASU32_RS20370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASU32_RS20385	COG5343	regulation of RNA biosynthetic process
ASU32_RS20400	COG3706	GGDEF domain
ASU32_RS20405	COG1113	amino acid transport
ASU32_RS20435	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS20450	COG1301	dicarboxylic acid transport
ASU32_RS20460	COG4565	transcriptional regulatory protein
ASU32_RS20465	COG0747	negative chemotaxis
ASU32_RS20470	COG4172	Belongs to the ABC transporter superfamily
ASU32_RS20475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASU32_RS20480	COG0601	transmembrane transport
ASU32_RS20490	COG3938	Belongs to the proline racemase family
ASU32_RS20495	COG1063	alcohol dehydrogenase
ASU32_RS20515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ASU32_RS20520	COG1113	amino acid transport
ASU32_RS20525	COG0477	Major facilitator Superfamily
ASU32_RS20530	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS20535	COG1063	alcohol dehydrogenase
ASU32_RS20540	COG1362	aminopeptidase activity
ASU32_RS20545	COG0047	phosphoribosylformylglycinamidine synthase activity
ASU32_RS20550	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ASU32_RS20570	COG0386	Belongs to the glutathione peroxidase family
ASU32_RS20580	COG0477	Major facilitator Superfamily
ASU32_RS20595	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ASU32_RS20605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ASU32_RS20625	COG2205	protein histidine kinase activity
ASU32_RS20630	COG0745	RESPONSE REGULATOR receiver
ASU32_RS20640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ASU32_RS20680	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS20680	COG3321	synthase
ASU32_RS20680	COG0604	alcohol dehydrogenase
ASU32_RS20685	COG1024	Enoyl-CoA hydratase
ASU32_RS20715	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ASU32_RS20725	COG1305	Transglutaminase-like
ASU32_RS20735	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ASU32_RS20770	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ASU32_RS20775	COG0788	formyltetrahydrofolate deformylase activity
ASU32_RS20800	COG2733	membrane
ASU32_RS20805	COG2326	polyphosphate kinase activity
ASU32_RS20825	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS20830	COG0583	DNA-binding transcription factor activity
ASU32_RS20840	COG0492	ferredoxin-NADP+ reductase activity
ASU32_RS20850	COG2224	Isocitrate lyase
ASU32_RS20870	COG5285	phytanoyl-CoA dioxygenase
ASU32_RS20880	COG1505	serine-type exopeptidase activity
ASU32_RS20895	COG2259	Doxx family
ASU32_RS20925	COG2326	polyphosphate kinase activity
ASU32_RS20935	COG1132	(ABC) transporter
ASU32_RS20940	COG1132	(ABC) transporter
ASU32_RS20950	COG1535	isochorismatase
ASU32_RS20950	COG3433	isochorismatase activity
ASU32_RS20955	COG1021	2,3-dihydroxybenzoate-AMP ligase
ASU32_RS20960	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS20965	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ASU32_RS20975	COG4607	ABC-type enterochelin transport system periplasmic component
ASU32_RS20985	COG3433	isochorismatase activity
ASU32_RS20985	COG1535	isochorismatase
ASU32_RS21035	COG0326	Molecular chaperone. Has ATPase activity
ASU32_RS21050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ASU32_RS21075	COG0688	phosphatidylethanolamine metabolic process
ASU32_RS21085	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ASU32_RS21100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ASU32_RS21100	COG2111	Na H antiporter
ASU32_RS21105	COG1006	Multisubunit Na H antiporter MnhC subunit
ASU32_RS21110	COG0651	ATP synthesis coupled electron transport
ASU32_RS21125	COG1320	monovalent cation:proton antiporter activity
ASU32_RS21130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ASU32_RS21155	COG1120	ATPase activity
ASU32_RS21160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASU32_RS21205	COG4555	ABC transporter
ASU32_RS21215	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ASU32_RS21220	COG0351	phosphomethylpyrimidine kinase
ASU32_RS21230	COG0351	phosphomethylpyrimidine kinase
ASU32_RS21265	COG0477	Major facilitator Superfamily
ASU32_RS21275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ASU32_RS21280	COG2022	thiamine diphosphate biosynthetic process
ASU32_RS21290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ASU32_RS21290	COG2022	thiamine diphosphate biosynthetic process
ASU32_RS21310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ASU32_RS21315	COG0515	serine threonine protein kinase
ASU32_RS21320	COG2132	Multicopper oxidase
ASU32_RS21325	COG1120	ATPase activity
ASU32_RS21330	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASU32_RS21335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ASU32_RS21350	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ASU32_RS21360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS21375	COG1132	(ABC) transporter
ASU32_RS21405	COG0657	acetylesterase activity
ASU32_RS21430	COG4941	Belongs to the sigma-70 factor family
ASU32_RS21440	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ASU32_RS21450	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ASU32_RS21460	COG1088	dTDP-glucose 4,6-dehydratase activity
ASU32_RS21465	COG1309	transcriptional regulator
ASU32_RS21470	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASU32_RS21475	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASU32_RS21510	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS21515	COG3971	2-oxopent-4-enoate hydratase activity
ASU32_RS21545	COG1414	Transcriptional regulator
ASU32_RS21550	COG1063	alcohol dehydrogenase
ASU32_RS21575	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS21580	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS21585	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ASU32_RS21590	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS21615	COG1012	belongs to the aldehyde dehydrogenase family
ASU32_RS21620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ASU32_RS21635	COG2070	2-Nitropropane dioxygenase
ASU32_RS21645	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS21680	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ASU32_RS21690	COG2124	cytochrome p450
ASU32_RS21695	COG0183	Belongs to the thiolase family
ASU32_RS21700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ASU32_RS21705	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS21715	COG1024	Enoyl-CoA hydratase
ASU32_RS21750	COG1309	transcriptional regulator
ASU32_RS21755	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS21760	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS21765	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS21770	COG1024	Enoyl-CoA hydratase
ASU32_RS21775	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS21780	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS21785	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS21800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASU32_RS21805	COG0346	lactoylglutathione lyase activity
ASU32_RS21810	COG2267	carboxylic ester hydrolase activity
ASU32_RS21815	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS21820	COG3976	FMN-binding domain protein
ASU32_RS21820	COG1053	succinate dehydrogenase
ASU32_RS21830	COG1053	succinate dehydrogenase
ASU32_RS21835	COG4638	Rieske (2fe-2S)
ASU32_RS21850	COG2030	dehydratase
ASU32_RS21865	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS21920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ASU32_RS21925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASU32_RS21940	COG0534	Mate efflux family protein
ASU32_RS21960	COG2508	Transcriptional regulator
ASU32_RS21965	COG2072	flavoprotein involved in K transport
ASU32_RS21990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ASU32_RS21990	COG1754	DNA topoisomerase type I activity
ASU32_RS21995	COG1846	Transcriptional regulator
ASU32_RS22005	COG1278	Cold shock
ASU32_RS22010	COG1205	dead DEAH box helicase
ASU32_RS22010	COG1111	helicase
ASU32_RS22025	COG1132	(ABC) transporter
ASU32_RS22080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ASU32_RS22085	COG0601	transmembrane transport
ASU32_RS22090	COG4166	transmembrane transport
ASU32_RS22095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ASU32_RS22115	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ASU32_RS22120	COG3663	DNA glycosylase
ASU32_RS22125	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ASU32_RS22130	COG0477	Major facilitator Superfamily
ASU32_RS22135	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ASU32_RS22155	COG0494	nUDIX hydrolase
ASU32_RS22180	COG2828	Protein conserved in bacteria
ASU32_RS22185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ASU32_RS22215	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ASU32_RS22220	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS22235	COG1024	Enoyl-CoA hydratase
ASU32_RS22255	COG2814	Major facilitator Superfamily
ASU32_RS22285	COG1408	metallophosphoesterase
ASU32_RS22300	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASU32_RS22305	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ASU32_RS22310	COG1764	response to oxidative stress
ASU32_RS22335	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS22345	COG0583	DNA-binding transcription factor activity
ASU32_RS22355	COG0768	penicillin binding
ASU32_RS22380	COG1528	Iron-storage protein
ASU32_RS22385	COG1309	transcriptional regulator
ASU32_RS22405	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ASU32_RS22445	COG3251	PFAM MbtH domain protein
ASU32_RS22455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ASU32_RS22460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ASU32_RS22470	COG0697	spore germination
ASU32_RS22475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASU32_RS22480	COG1017	nitric oxide dioxygenase activity
ASU32_RS22480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ASU32_RS22500	COG2807	transmembrane transport
ASU32_RS22505	COG0583	DNA-binding transcription factor activity
ASU32_RS22520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ASU32_RS22535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ASU32_RS22565	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASU32_RS22570	COG0564	pseudouridine synthase activity
ASU32_RS22585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ASU32_RS22620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ASU32_RS22635	COG4974	Belongs to the 'phage' integrase family
ASU32_RS22700	COG0640	Transcriptional regulator
ASU32_RS22715	COG1793	dna ligase
ASU32_RS22720	COG2318	DinB family
ASU32_RS22730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ASU32_RS22740	COG4977	sequence-specific DNA binding
ASU32_RS22745	COG0343	queuine tRNA-ribosyltransferase activity
ASU32_RS22785	COG0287	Prephenate dehydrogenase
ASU32_RS22835	COG0739	heme binding
ASU32_RS22910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ASU32_RS22950	COG2030	dehydratase
ASU32_RS22970	COG0385	Bile acid
ASU32_RS22980	COG0640	Transcriptional regulator
ASU32_RS23035	COG2197	response regulator
ASU32_RS23040	COG2815	serine threonine protein kinase
ASU32_RS23040	COG0515	serine threonine protein kinase
ASU32_RS23150	COG0183	Belongs to the thiolase family
ASU32_RS23195	COG1216	Glycosyl transferase, family 2
ASU32_RS23200	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS23210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ASU32_RS23250	COG1476	TRANSCRIPTIONal
ASU32_RS23260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ASU32_RS23265	COG1012	belongs to the aldehyde dehydrogenase family
ASU32_RS23270	COG0006	proline dipeptidase activity
ASU32_RS23275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ASU32_RS23280	COG1473	amidohydrolase
ASU32_RS23290	COG1960	acyl-CoA dehydrogenase activity
ASU32_RS23295	COG1309	transcriptional regulator
ASU32_RS23305	COG1028	Short-chain dehydrogenase reductase Sdr
ASU32_RS23315	COG4221	oxidoreductase activity
ASU32_RS23320	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ASU32_RS23335	COG1122	ATPase activity
ASU32_RS23340	COG1268	BioY protein
ASU32_RS23395	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ASU32_RS23435	COG1174	glycine betaine transport
ASU32_RS23445	COG1174	glycine betaine transport
ASU32_RS23450	COG3973	AAA domain
ASU32_RS23475	COG3268	Saccharopine dehydrogenase
ASU32_RS23480	COG0318	PFAM AMP-dependent synthetase and ligase
ASU32_RS23555	COG0360	Binds together with S18 to 16S ribosomal RNA
ASU32_RS23565	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ASU32_RS23620	COG1309	transcriptional regulator
ASU32_RS23635	COG0183	Belongs to the thiolase family
ASU32_RS23640	COG1024	Enoyl-CoA hydratase
ASU32_RS23640	COG1250	3-hydroxyacyl-CoA dehydrogenase
ASU32_RS23675	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ASU32_RS23690	COG1260	myo-inositol-1-phosphate synthase
ASU32_RS23750	COG1358	cellular component organization or biogenesis
ASU32_RS23765	COG1297	OPT oligopeptide transporter protein
ASU32_RS23785	COG2814	Major facilitator Superfamily
ASU32_RS23790	COG4221	oxidoreductase activity
ASU32_RS23800	COG4122	O-methyltransferase activity
ASU32_RS23820	COG0495	leucyl-tRNA aminoacylation
ASU32_RS23865	COG1678	Uncharacterized ACR, COG1678
ASU32_RS23885	COG0617	tRNA 3'-terminal CCA addition
ASU32_RS23910	COG0519	Catalyzes the synthesis of GMP from XMP
ASU32_RS23915	COG1012	belongs to the aldehyde dehydrogenase family
ASU32_RS23920	COG1595	DNA-templated transcription, initiation
ASU32_RS23940	COG3409	Peptidoglycan-binding domain 1 protein
ASU32_RS23940	COG0860	N-Acetylmuramoyl-L-alanine amidase
ASU32_RS23955	COG1192	Involved in chromosome partitioning
ASU32_RS23965	COG0357	Ribosomal RNA small subunit methyltransferase G
ASU32_RS23975	COG0706	membrane insertase activity
ASU32_RS23980	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ASU32_RS23985	COG0594	ribonuclease P activity