locus-tag	class	description
IDJ81_RS00025	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IDJ81_RS00030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IDJ81_RS00040	COG1301	dicarboxylic acid transport
IDJ81_RS00045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IDJ81_RS00080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IDJ81_RS00085	COG0706	membrane insertase activity
IDJ81_RS00090	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IDJ81_RS00095	COG0594	ribonuclease P activity
IDJ81_RS00100	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IDJ81_RS00130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IDJ81_RS00145	COG2866	Carboxypeptidase
IDJ81_RS00150	COG1619	proteins homologs of microcin C7 resistance protein MccF
IDJ81_RS00155	COG0295	cytidine deaminase activity
IDJ81_RS00165	COG5328	Belongs to the UPF0262 family
IDJ81_RS00170	COG0305	Participates in initiation and elongation during chromosome replication
IDJ81_RS00175	COG0717	Belongs to the dCTP deaminase family
IDJ81_RS00180	COG4771	TonB-dependent receptor
IDJ81_RS00185	COG1309	transcriptional regulator
IDJ81_RS00205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IDJ81_RS00255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IDJ81_RS00260	COG3047	cAMP biosynthetic process
IDJ81_RS00270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IDJ81_RS00305	COG1522	sequence-specific DNA binding
IDJ81_RS00330	COG1522	sequence-specific DNA binding
IDJ81_RS00340	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IDJ81_RS00380	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IDJ81_RS00390	COG1199	ATP-dependent helicase activity
IDJ81_RS00390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IDJ81_RS00400	COG0789	Transcriptional regulator
IDJ81_RS00415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IDJ81_RS00445	COG0438	transferase activity, transferring glycosyl groups
IDJ81_RS00450	COG0596	Alpha beta hydrolase
IDJ81_RS00450	COG2945	thiolester hydrolase activity
IDJ81_RS00455	COG1012	belongs to the aldehyde dehydrogenase family
IDJ81_RS00460	COG1702	phosphate starvation-inducible protein PhoH
IDJ81_RS00485	COG0730	response to heat
IDJ81_RS00500	COG0450	alkyl hydroperoxide reductase
IDJ81_RS00525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IDJ81_RS00530	COG0446	pyridine nucleotide-disulphide oxidoreductase
IDJ81_RS00545	COG1846	Transcriptional regulator
IDJ81_RS00555	COG1309	transcriptional regulator
IDJ81_RS00600	COG0745	RESPONSE REGULATOR receiver
IDJ81_RS00640	COG0297	glycogen (starch) synthase activity
IDJ81_RS00655	COG0297	glycogen (starch) synthase activity
IDJ81_RS00660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IDJ81_RS00670	COG0156	8-amino-7-oxononanoate synthase activity
IDJ81_RS00690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IDJ81_RS00695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IDJ81_RS00700	COG1309	transcriptional regulator
IDJ81_RS00725	COG2909	trisaccharide binding
IDJ81_RS00775	COG5265	(ABC) transporter
IDJ81_RS00780	COG0659	secondary active sulfate transmembrane transporter activity
IDJ81_RS00790	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IDJ81_RS00795	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IDJ81_RS00815	COG0629	single-stranded DNA binding
IDJ81_RS00840	COG1999	signal sequence binding
IDJ81_RS00845	COG2983	Belongs to the UPF0260 family
IDJ81_RS00860	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IDJ81_RS00860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IDJ81_RS00870	COG2827	Endonuclease containing a URI domain
IDJ81_RS00875	COG1448	Aminotransferase
IDJ81_RS00945	COG1024	Enoyl-CoA hydratase
IDJ81_RS00975	COG1376	ErfK ybiS ycfS ynhG family protein
IDJ81_RS00980	COG0037	tRNA processing
IDJ81_RS00990	COG1426	Protein conserved in bacteria
IDJ81_RS01015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IDJ81_RS01030	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IDJ81_RS01035	COG1505	serine-type exopeptidase activity
IDJ81_RS01050	COG1902	pentaerythritol trinitrate reductase activity
IDJ81_RS01060	COG0321	lipoyl(octanoyl) transferase activity
IDJ81_RS01085	COG1393	Belongs to the ArsC family
IDJ81_RS01090	COG2080	2 iron, 2 sulfur cluster binding
IDJ81_RS01095	COG0235	Class ii aldolase
IDJ81_RS01100	COG0534	Mate efflux family protein
IDJ81_RS01125	COG2072	flavoprotein involved in K transport
IDJ81_RS01130	COG1058	Belongs to the CinA family
IDJ81_RS01130	COG1546	Belongs to the CinA family
IDJ81_RS01150	COG0081	regulation of translation
IDJ81_RS01155	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IDJ81_RS01160	COG0250	Participates in transcription elongation, termination and antitermination
IDJ81_RS01180	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IDJ81_RS01230	COG3384	dioxygenase
IDJ81_RS01235	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IDJ81_RS01235	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IDJ81_RS01255	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IDJ81_RS01265	COG0489	protein tyrosine kinase activity
IDJ81_RS01270	COG0330	HflC and HflK could
IDJ81_RS01285	COG2226	methyltransferase
IDJ81_RS01290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IDJ81_RS01315	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IDJ81_RS01330	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IDJ81_RS01340	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IDJ81_RS01345	COG0085	RNA polymerase activity
IDJ81_RS01355	COG3655	Transcriptional regulator
IDJ81_RS01360	COG2885	chlorophyll binding
IDJ81_RS01365	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IDJ81_RS01370	COG0222	ribosome binding
IDJ81_RS01375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IDJ81_RS01375	COG0475	glutathione-regulated potassium exporter activity
IDJ81_RS01395	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IDJ81_RS01400	COG0459	protein refolding
IDJ81_RS01415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IDJ81_RS01415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IDJ81_RS01420	COG3920	Histidine kinase
IDJ81_RS01430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IDJ81_RS01450	COG2814	Major facilitator Superfamily
IDJ81_RS01455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IDJ81_RS01460	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IDJ81_RS01470	COG2890	protein-(glutamine-N5) methyltransferase activity
IDJ81_RS01475	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IDJ81_RS01480	COG0124	histidyl-tRNA synthetase
IDJ81_RS01495	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IDJ81_RS01500	COG0668	transmembrane transport
IDJ81_RS01505	COG0312	modulator of DNA gyrase
IDJ81_RS01515	COG1137	ATPase activity
IDJ81_RS01520	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IDJ81_RS01530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IDJ81_RS01540	COG2199	diguanylate cyclase activity
IDJ81_RS01550	COG1012	belongs to the aldehyde dehydrogenase family
IDJ81_RS01560	COG0281	malic enzyme
IDJ81_RS01560	COG0280	phosphate acetyltransferase
IDJ81_RS01565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IDJ81_RS01585	COG1250	3-hydroxyacyl-CoA dehydrogenase
IDJ81_RS01600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IDJ81_RS01610	COG3483	tryptophan 2,3-dioxygenase activity
IDJ81_RS01620	COG4166	transmembrane transport
IDJ81_RS01675	COG0156	8-amino-7-oxononanoate synthase activity
IDJ81_RS01685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IDJ81_RS01760	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IDJ81_RS01760	COG2885	chlorophyll binding
IDJ81_RS01765	COG2032	superoxide dismutase activity
IDJ81_RS01775	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IDJ81_RS01790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IDJ81_RS01795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IDJ81_RS01800	COG1278	Cold shock
IDJ81_RS01805	COG1253	flavin adenine dinucleotide binding
IDJ81_RS01830	COG0004	ammonium transporteR
IDJ81_RS01835	COG0347	Belongs to the P(II) protein family
IDJ81_RS01850	COG0433	COG0433 Predicted ATPase
IDJ81_RS01860	COG0564	pseudouridine synthase activity
IDJ81_RS01870	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IDJ81_RS01915	COG0514	ATP-dependent DNA helicase (RecQ)
IDJ81_RS01930	COG0183	Belongs to the thiolase family
IDJ81_RS01935	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IDJ81_RS01940	COG2326	polyphosphate kinase activity
IDJ81_RS01945	COG3186	Phenylalanine-4-hydroxylase
IDJ81_RS01960	COG1968	undecaprenyl-diphosphatase activity
IDJ81_RS01970	COG1132	(ABC) transporter
IDJ81_RS01995	COG0183	Belongs to the thiolase family
IDJ81_RS02025	COG0070	glutamate synthase
IDJ81_RS02025	COG0069	glutamate synthase activity
IDJ81_RS02025	COG0067	glutamate synthase
IDJ81_RS02035	COG2197	response regulator
IDJ81_RS02040	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IDJ81_RS02040	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IDJ81_RS02050	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IDJ81_RS02060	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IDJ81_RS02090	COG0495	leucyl-tRNA aminoacylation
IDJ81_RS02105	COG1028	Short-chain dehydrogenase reductase Sdr
IDJ81_RS02125	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IDJ81_RS02130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IDJ81_RS02140	COG0739	heme binding
IDJ81_RS02145	COG2833	Protein of unknown function (DUF455)
IDJ81_RS02150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IDJ81_RS02155	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IDJ81_RS02175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IDJ81_RS02210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IDJ81_RS02215	COG2902	Dehydrogenase
IDJ81_RS02225	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IDJ81_RS02230	COG4152	abc transporter atp-binding protein
IDJ81_RS02265	COG0482	sulfurtransferase activity
IDJ81_RS02290	COG0259	pyridoxamine-phosphate oxidase activity
IDJ81_RS02295	COG0484	heat shock protein binding
IDJ81_RS02300	COG1295	ribonuclease BN
IDJ81_RS02305	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IDJ81_RS02320	COG3547	Transposase (IS116 IS110 IS902 family)
IDJ81_RS02350	COG0489	protein tyrosine kinase activity
IDJ81_RS02375	COG2226	methyltransferase
IDJ81_RS02385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IDJ81_RS02390	COG0022	dehydrogenase e1 component
IDJ81_RS02390	COG0508	dehydrogenase complex catalyzes the overall conversion of
IDJ81_RS02415	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IDJ81_RS02420	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IDJ81_RS02430	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IDJ81_RS02440	COG0793	Belongs to the peptidase S41A family
IDJ81_RS02450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IDJ81_RS02455	COG0799	negative regulation of ribosome biogenesis
IDJ81_RS02460	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IDJ81_RS02465	COG0667	Aldo Keto reductase
IDJ81_RS02470	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IDJ81_RS02475	COG0739	heme binding
IDJ81_RS02490	COG0318	PFAM AMP-dependent synthetase and ligase
IDJ81_RS02500	COG0438	transferase activity, transferring glycosyl groups
IDJ81_RS02540	COG1793	dna ligase
IDJ81_RS02550	COG1872	DUF167
IDJ81_RS02565	COG0113	porphobilinogen synthase activity
IDJ81_RS02570	COG0739	heme binding
IDJ81_RS02585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IDJ81_RS02590	COG1329	Transcriptional regulator
IDJ81_RS02605	COG0009	L-threonylcarbamoyladenylate synthase
IDJ81_RS02610	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS02625	COG1956	GAF domain-containing protein
IDJ81_RS02665	COG0357	Ribosomal RNA small subunit methyltransferase G
IDJ81_RS02670	COG0445	tRNA wobble uridine modification
IDJ81_RS02675	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IDJ81_RS02705	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IDJ81_RS02710	COG1981	membrane
IDJ81_RS02715	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IDJ81_RS02720	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IDJ81_RS02725	COG0424	maF-like protein
IDJ81_RS02730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IDJ81_RS02735	COG0237	dephospho-CoA kinase activity
IDJ81_RS02740	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IDJ81_RS02745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IDJ81_RS02775	COG0316	Belongs to the HesB IscA family
IDJ81_RS02805	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IDJ81_RS02815	COG2972	Histidine kinase
IDJ81_RS02850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IDJ81_RS02855	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IDJ81_RS02865	COG1612	heme a metabolic process
IDJ81_RS02875	COG2022	thiamine diphosphate biosynthetic process
IDJ81_RS02895	COG0405	Gamma-glutamyltransferase
IDJ81_RS02900	COG0167	dihydroorotate dehydrogenase activity
IDJ81_RS02910	COG0719	Fe-S assembly protein
IDJ81_RS02925	COG0396	ATPase activity
IDJ81_RS02935	COG0719	Fe-S assembly protein
IDJ81_RS02940	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IDJ81_RS02945	COG2151	metal-sulfur cluster biosynthetic enzyme
IDJ81_RS02955	COG0316	Belongs to the HesB IscA family
IDJ81_RS02970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IDJ81_RS02985	COG2814	Major facilitator Superfamily
IDJ81_RS02995	COG1570	exodeoxyribonuclease VII activity
IDJ81_RS03015	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IDJ81_RS03020	COG0590	tRNA wobble adenosine to inosine editing
IDJ81_RS03035	COG3279	Response regulator of the LytR AlgR family
IDJ81_RS03040	COG3275	phosphorelay sensor kinase activity
IDJ81_RS03060	COG0501	Belongs to the peptidase M48B family
IDJ81_RS03110	COG1742	UPF0060 membrane protein
IDJ81_RS03115	COG3547	Transposase (IS116 IS110 IS902 family)
IDJ81_RS03120	COG3547	Transposase (IS116 IS110 IS902 family)
IDJ81_RS03145	COG1028	Short-chain dehydrogenase reductase Sdr
IDJ81_RS03160	COG0668	transmembrane transport
IDJ81_RS03195	COG1285	pathogenesis
IDJ81_RS03260	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IDJ81_RS03270	COG0477	Major facilitator Superfamily
IDJ81_RS03285	COG2207	Transcriptional regulator
IDJ81_RS03310	COG5489	Protein of unknown function (DUF736)
IDJ81_RS03335	COG2814	Major facilitator Superfamily
IDJ81_RS03340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IDJ81_RS03345	COG3958	Transketolase
IDJ81_RS03350	COG3959	Transketolase, thiamine diphosphate binding domain
IDJ81_RS03360	COG1082	Xylose isomerase domain protein TIM barrel
IDJ81_RS03365	COG1304	FMN binding
IDJ81_RS03380	COG4948	Mandelate Racemase Muconate Lactonizing
IDJ81_RS03385	COG0179	Fumarylacetoacetate (FAA) hydrolase
IDJ81_RS03390	COG1028	Short-chain dehydrogenase reductase Sdr
IDJ81_RS03395	COG3618	amidohydrolase
IDJ81_RS03400	COG3250	beta-galactosidase activity
IDJ81_RS03410	COG2211	Major facilitator Superfamily
IDJ81_RS03420	COG2186	Transcriptional regulator
IDJ81_RS03440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IDJ81_RS03450	COG1024	Enoyl-CoA hydratase
IDJ81_RS03455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IDJ81_RS03460	COG0572	uridine kinase
IDJ81_RS03470	COG3250	beta-galactosidase activity
IDJ81_RS03480	COG1028	Short-chain dehydrogenase reductase Sdr
IDJ81_RS03500	COG1472	Belongs to the glycosyl hydrolase 3 family
IDJ81_RS03525	COG1609	Transcriptional regulator
IDJ81_RS03535	COG1082	Xylose isomerase domain protein TIM barrel
IDJ81_RS03540	COG0517	IMP dehydrogenase activity
IDJ81_RS03540	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IDJ81_RS03545	COG2176	DNA-directed DNA polymerase activity
IDJ81_RS03555	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IDJ81_RS03560	COG0784	Response regulator, receiver
IDJ81_RS03560	COG2198	Histidine kinase
IDJ81_RS03560	COG2205	protein histidine kinase activity
IDJ81_RS03570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IDJ81_RS03585	COG2081	HI0933 family
IDJ81_RS03595	COG1473	amidohydrolase
IDJ81_RS03610	COG0138	bifunctional purine biosynthesis protein purh
IDJ81_RS03620	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IDJ81_RS03635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IDJ81_RS03650	COG0488	(ABC) transporter
IDJ81_RS03660	COG2850	peptidyl-arginine hydroxylation
IDJ81_RS03685	COG1228	amidohydrolase
IDJ81_RS03690	COG3104	oligopeptide transport
IDJ81_RS03695	COG2188	Transcriptional regulator
IDJ81_RS03720	COG2733	membrane
IDJ81_RS03755	COG2086	electron transfer activity
IDJ81_RS03765	COG0045	succinate-CoA ligase (ADP-forming) activity
IDJ81_RS03770	COG1218	3'(2'),5'-bisphosphate nucleotidase
IDJ81_RS03780	COG1253	flavin adenine dinucleotide binding
IDJ81_RS03790	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IDJ81_RS03795	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IDJ81_RS03805	COG0196	riboflavin kinase activity
IDJ81_RS03820	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IDJ81_RS03825	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IDJ81_RS03830	COG0588	phosphoglycerate mutase activity
IDJ81_RS03875	COG0308	aminopeptidase N
IDJ81_RS03880	COG1496	oxidoreductase activity
IDJ81_RS03885	COG0723	plastoquinol--plastocyanin reductase activity
IDJ81_RS03895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IDJ81_RS03895	COG2857	Cytochrome c1
IDJ81_RS03900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IDJ81_RS03925	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IDJ81_RS03930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IDJ81_RS03945	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IDJ81_RS03950	COG1192	Involved in chromosome partitioning
IDJ81_RS03970	COG1201	RNA secondary structure unwinding
IDJ81_RS04010	COG1494	fructose-1,6-bisphosphatase
IDJ81_RS04025	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IDJ81_RS04030	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IDJ81_RS04045	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IDJ81_RS04050	COG0072	phenylalanine-tRNA ligase activity
IDJ81_RS04055	COG4221	oxidoreductase activity
IDJ81_RS04060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IDJ81_RS04065	COG2205	protein histidine kinase activity
IDJ81_RS04130	COG2814	Major facilitator Superfamily
IDJ81_RS04135	COG1566	PFAM secretion protein HlyD family protein
IDJ81_RS04160	COG4206	TonB-dependent receptor
IDJ81_RS04215	COG1802	Transcriptional regulator
IDJ81_RS04225	COG2027	D-alanyl-D-alanine carboxypeptidase
IDJ81_RS04235	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IDJ81_RS04240	COG4948	Mandelate Racemase Muconate Lactonizing
IDJ81_RS04305	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IDJ81_RS04310	COG4774	siderophore transport
IDJ81_RS04315	COG1309	transcriptional regulator
IDJ81_RS04325	COG1028	Short-chain dehydrogenase reductase Sdr
IDJ81_RS04330	COG4638	Rieske (2fe-2S)
IDJ81_RS04335	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS04345	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS04360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IDJ81_RS04365	COG0183	Belongs to the thiolase family
IDJ81_RS04375	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS04385	COG1024	Enoyl-CoA hydratase
IDJ81_RS04405	COG1024	Enoyl-CoA hydratase
IDJ81_RS04420	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IDJ81_RS04435	COG0183	Belongs to the thiolase family
IDJ81_RS04440	COG1024	Enoyl-CoA hydratase
IDJ81_RS04445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IDJ81_RS04450	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS04460	COG2267	carboxylic ester hydrolase activity
IDJ81_RS04465	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS04470	COG1028	Short-chain dehydrogenase reductase Sdr
IDJ81_RS04490	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
IDJ81_RS04505	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IDJ81_RS04525	COG0066	3-isopropylmalate dehydratase activity
IDJ81_RS04540	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IDJ81_RS04550	COG0824	Thioesterase
IDJ81_RS04565	COG0330	HflC and HflK could
IDJ81_RS04585	COG0582	viral genome integration into host DNA
IDJ81_RS04595	COG0741	lytic transglycosylase activity
IDJ81_RS04610	COG4974	Belongs to the 'phage' integrase family
IDJ81_RS04615	COG4974	Belongs to the 'phage' integrase family
IDJ81_RS04620	COG4974	Belongs to the 'phage' integrase family
IDJ81_RS04630	COG1475	DNA binding
IDJ81_RS04635	COG2925	Exonuclease
IDJ81_RS04670	COG4227	nucleotidyltransferase activity
IDJ81_RS04690	COG0629	single-stranded DNA binding
IDJ81_RS04765	COG1104	cysteine desulfurase activity
IDJ81_RS04895	COG0318	PFAM AMP-dependent synthetase and ligase
IDJ81_RS04970	COG4569	acetaldehyde dehydrogenase (acetylating) activity
IDJ81_RS04990	COG2267	carboxylic ester hydrolase activity
IDJ81_RS04995	COG0318	PFAM AMP-dependent synthetase and ligase
IDJ81_RS05000	COG4771	TonB-dependent receptor
IDJ81_RS05055	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS05060	COG0633	Ferredoxin
IDJ81_RS05070	COG2188	Transcriptional regulator
IDJ81_RS05075	COG2070	2-Nitropropane dioxygenase
IDJ81_RS05095	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS05100	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS05110	COG2072	flavoprotein involved in K transport
IDJ81_RS05120	COG4771	TonB-dependent receptor
IDJ81_RS05125	COG1538	Outer membrane efflux protein
IDJ81_RS05150	COG0582	viral genome integration into host DNA
IDJ81_RS05165	COG0604	alcohol dehydrogenase
IDJ81_RS05180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IDJ81_RS05180	COG1017	nitric oxide dioxygenase activity
IDJ81_RS05200	COG1959	2 iron, 2 sulfur cluster binding
IDJ81_RS05210	COG0387	Pfam Sodium calcium exchanger
IDJ81_RS05225	COG0463	Glycosyl transferase, family 2
IDJ81_RS05235	COG1012	belongs to the aldehyde dehydrogenase family
IDJ81_RS05245	COG3300	MHYT domain
IDJ81_RS05245	COG5001	Diguanylate cyclase
IDJ81_RS05255	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IDJ81_RS05260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IDJ81_RS05260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IDJ81_RS05270	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IDJ81_RS05275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IDJ81_RS05310	COG2942	2-epimerase
IDJ81_RS05330	COG0793	Belongs to the peptidase S41A family
IDJ81_RS05335	COG0439	Biotin carboxylase
IDJ81_RS05340	COG0511	ligase activity, forming carbon-carbon bonds
IDJ81_RS05370	COG1609	Transcriptional regulator
IDJ81_RS05390	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IDJ81_RS05415	COG1482	cell wall glycoprotein biosynthetic process
IDJ81_RS05430	COG1758	RNA polymerase activity
IDJ81_RS05435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IDJ81_RS05440	COG2259	Doxx family
IDJ81_RS05445	COG4771	TonB-dependent receptor
IDJ81_RS05455	COG1741	Belongs to the pirin family
IDJ81_RS05460	COG2353	YceI-like domain
IDJ81_RS05465	COG1741	Belongs to the pirin family
IDJ81_RS05470	COG0583	DNA-binding transcription factor activity
IDJ81_RS05485	COG4771	TonB-dependent receptor
IDJ81_RS05505	COG1477	protein flavinylation
IDJ81_RS05525	COG4771	TonB-dependent receptor
IDJ81_RS05545	COG0443	Heat shock 70 kDa protein
IDJ81_RS05550	COG1024	Enoyl-CoA hydratase
IDJ81_RS05550	COG1250	3-hydroxyacyl-CoA dehydrogenase
IDJ81_RS05560	COG0318	PFAM AMP-dependent synthetase and ligase
IDJ81_RS05575	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS05590	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS05615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IDJ81_RS05620	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IDJ81_RS05625	COG0181	hydroxymethylbilane synthase activity
IDJ81_RS05640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IDJ81_RS05660	COG0556	nucleotide-excision repair
IDJ81_RS05675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IDJ81_RS05675	COG0596	Alpha beta hydrolase
IDJ81_RS05675	COG2226	methyltransferase
IDJ81_RS05680	COG2308	Evidence 4 Homologs of previously reported genes of
IDJ81_RS05700	COG4566	intracellular signal transduction
IDJ81_RS05710	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IDJ81_RS05715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IDJ81_RS05730	COG1217	gtp-binding protein TYPA
IDJ81_RS05735	COG4771	TonB-dependent receptor
IDJ81_RS05750	COG4181	ATPase activity
IDJ81_RS05760	COG1381	Involved in DNA repair and RecF pathway recombination
IDJ81_RS05765	COG0473	3-isopropylmalate dehydrogenase activity
IDJ81_RS05770	COG0463	Glycosyl transferase, family 2
IDJ81_RS05800	COG2967	ApaG domain
IDJ81_RS05810	COG0248	Ppx GppA phosphatase
IDJ81_RS05815	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IDJ81_RS05820	COG0583	DNA-binding transcription factor activity
IDJ81_RS05830	COG1196	nuclear chromosome segregation
IDJ81_RS05850	COG1194	a g-specific adenine glycosylase
IDJ81_RS05865	COG2816	NAD+ diphosphatase activity
IDJ81_RS05875	COG0730	response to heat
IDJ81_RS05885	COG2239	Acts as a magnesium transporter
IDJ81_RS05900	COG0583	DNA-binding transcription factor activity
IDJ81_RS05910	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IDJ81_RS05915	COG4974	Belongs to the 'phage' integrase family
IDJ81_RS06000	COG3701	Conjugal transfer protein
IDJ81_RS06020	COG3451	type IV secretory pathway VirB4
IDJ81_RS06035	COG4962	Type ii secretion system protein e
IDJ81_RS06110	COG1196	nuclear chromosome segregation
IDJ81_RS06110	COG0741	lytic transglycosylase activity
IDJ81_RS06110	COG0739	heme binding
IDJ81_RS06150	COG1476	TRANSCRIPTIONal
IDJ81_RS06165	COG5489	Protein of unknown function (DUF736)
IDJ81_RS06185	COG3118	belongs to the thioredoxin family
IDJ81_RS06195	COG2095	MarC family integral membrane protein
IDJ81_RS06205	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IDJ81_RS06215	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IDJ81_RS06280	COG0454	-acetyltransferase
IDJ81_RS06280	COG0456	acetyltransferase
IDJ81_RS06295	COG1131	(ABC) transporter
IDJ81_RS06305	COG0312	modulator of DNA gyrase
IDJ81_RS06330	COG0519	Catalyzes the synthesis of GMP from XMP
IDJ81_RS06330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IDJ81_RS06340	COG0318	PFAM AMP-dependent synthetase and ligase
IDJ81_RS06350	COG1760	l-serine dehydratase
IDJ81_RS06380	COG0204	Acyl-transferase
IDJ81_RS06385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IDJ81_RS06390	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS06395	COG5001	Diguanylate cyclase
IDJ81_RS06405	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IDJ81_RS06410	COG0318	PFAM AMP-dependent synthetase and ligase
IDJ81_RS06415	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IDJ81_RS06420	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IDJ81_RS06445	COG3746	phosphate-selective porin O and P
IDJ81_RS06450	COG0686	Belongs to the AlaDH PNT family
IDJ81_RS06465	COG2884	Cell division ATP-binding protein ftsE
IDJ81_RS06485	COG0287	Prephenate dehydrogenase
IDJ81_RS06490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IDJ81_RS06495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IDJ81_RS06500	COG2813	Specifically methylates the guanine in position
IDJ81_RS06500	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IDJ81_RS06505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IDJ81_RS06505	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IDJ81_RS06515	COG0469	pyruvate kinase activity
IDJ81_RS06525	COG3750	Belongs to the UPF0335 family
IDJ81_RS06535	COG0393	Putative heavy-metal-binding
IDJ81_RS06545	COG0217	transcriptional regulatory protein
IDJ81_RS06555	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IDJ81_RS06565	COG1393	Belongs to the ArsC family
IDJ81_RS06580	COG0584	glycerophosphoryl diester phosphodiesterase
IDJ81_RS06590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IDJ81_RS06595	COG0527	aspartate kinase activity
IDJ81_RS06600	COG0471	metal ion transport
IDJ81_RS06600	COG3273	potassium ion transport
IDJ81_RS06605	COG2070	2-Nitropropane dioxygenase
IDJ81_RS06615	COG2119	membrane
IDJ81_RS06630	COG2166	iron-sulfur cluster assembly
IDJ81_RS06670	COG1842	Phage shock protein A
IDJ81_RS06680	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IDJ81_RS06685	COG0779	Required for maturation of 30S ribosomal subunits
IDJ81_RS06700	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IDJ81_RS06705	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IDJ81_RS06710	COG1435	thymidine kinase activity
IDJ81_RS06720	COG1994	Peptidase M50
IDJ81_RS06730	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IDJ81_RS06735	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IDJ81_RS06740	COG1185	polyribonucleotide nucleotidyltransferase activity
IDJ81_RS06760	COG0842	Transport permease protein
IDJ81_RS06775	COG0582	viral genome integration into host DNA
IDJ81_RS06795	COG2271	Major facilitator Superfamily
IDJ81_RS06800	COG0508	dehydrogenase complex catalyzes the overall conversion of
IDJ81_RS06805	COG0022	dehydrogenase e1 component
IDJ81_RS06810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IDJ81_RS06815	COG0583	DNA-binding transcription factor activity
IDJ81_RS06825	COG4771	TonB-dependent receptor
IDJ81_RS06830	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IDJ81_RS06855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IDJ81_RS06865	COG1846	Transcriptional regulator
IDJ81_RS06870	COG1764	response to oxidative stress
IDJ81_RS06875	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IDJ81_RS06885	COG2079	MmgE PrpD family protein
IDJ81_RS06895	COG3800	Transcriptional regulator
IDJ81_RS06895	COG1396	sequence-specific DNA binding
IDJ81_RS06910	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS06920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IDJ81_RS06930	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IDJ81_RS06930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IDJ81_RS06945	COG1294	oxidase, subunit
IDJ81_RS06955	COG4988	ABC transporter
IDJ81_RS06960	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IDJ81_RS06965	COG1473	amidohydrolase
IDJ81_RS06970	COG1301	dicarboxylic acid transport
IDJ81_RS06975	COG0251	oxidation-reduction process
IDJ81_RS06980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IDJ81_RS06985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IDJ81_RS06990	COG4206	TonB-dependent receptor
IDJ81_RS07000	COG1473	amidohydrolase
IDJ81_RS07025	COG4771	TonB-dependent receptor
IDJ81_RS07030	COG1012	belongs to the aldehyde dehydrogenase family
IDJ81_RS07035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IDJ81_RS07050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IDJ81_RS07060	COG0659	secondary active sulfate transmembrane transporter activity
IDJ81_RS07065	COG0456	acetyltransferase
IDJ81_RS07070	COG3811	Belongs to the UPF0386 family
IDJ81_RS07080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IDJ81_RS07100	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IDJ81_RS07105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IDJ81_RS07120	COG3210	domain, Protein
IDJ81_RS07200	COG2271	Major facilitator Superfamily
IDJ81_RS07205	COG1028	Short-chain dehydrogenase reductase Sdr
IDJ81_RS07210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IDJ81_RS07260	COG0463	Glycosyl transferase, family 2
IDJ81_RS07280	COG0640	Transcriptional regulator
IDJ81_RS07285	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IDJ81_RS07300	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IDJ81_RS07305	COG0509	glycine decarboxylation via glycine cleavage system
IDJ81_RS07310	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IDJ81_RS07315	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IDJ81_RS07365	COG2274	protein secretion by the type I secretion system
IDJ81_RS07385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IDJ81_RS07390	COG5001	Diguanylate cyclase
IDJ81_RS07395	COG0047	phosphoribosylformylglycinamidine synthase activity
IDJ81_RS07400	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IDJ81_RS07405	COG0612	Peptidase, M16
IDJ81_RS07410	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IDJ81_RS07435	COG0424	maF-like protein
IDJ81_RS07440	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IDJ81_RS07450	COG1192	Involved in chromosome partitioning
IDJ81_RS07455	COG0322	excinuclease ABC activity
IDJ81_RS07460	COG5001	Diguanylate cyclase
IDJ81_RS07460	COG5002	protein histidine kinase activity
IDJ81_RS07470	COG1946	Acyl-CoA thioesterase
IDJ81_RS07485	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IDJ81_RS07495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IDJ81_RS07500	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IDJ81_RS07510	COG0596	Alpha beta hydrolase
IDJ81_RS07515	COG0300	oxidoreductase activity
IDJ81_RS07540	COG0625	glutathione transferase activity
IDJ81_RS07550	COG1733	regulation of RNA biosynthetic process
IDJ81_RS07585	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IDJ81_RS07590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IDJ81_RS07595	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IDJ81_RS07600	COG0729	surface antigen
IDJ81_RS07625	COG0174	glutamine synthetase
IDJ81_RS07630	COG0347	Belongs to the P(II) protein family
IDJ81_RS07655	COG0024	Methionine aminopeptidase
IDJ81_RS07660	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IDJ81_RS07670	COG2154	pterin-4-alpha-carbinolamine dehydratase
IDJ81_RS07685	COG2070	2-Nitropropane dioxygenase
IDJ81_RS07725	COG2001	Belongs to the MraZ family
IDJ81_RS07730	COG0275	rRNA processing
IDJ81_RS07745	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IDJ81_RS07755	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IDJ81_RS07760	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IDJ81_RS07770	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IDJ81_RS07775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IDJ81_RS07780	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IDJ81_RS07785	COG1181	Belongs to the D-alanine--D-alanine ligase family
IDJ81_RS07790	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IDJ81_RS07795	COG0849	cell division
IDJ81_RS07815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IDJ81_RS07820	COG0670	Belongs to the BI1 family
IDJ81_RS07835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IDJ81_RS07840	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IDJ81_RS07850	COG0583	DNA-binding transcription factor activity
IDJ81_RS07855	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IDJ81_RS07860	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IDJ81_RS07870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IDJ81_RS07875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IDJ81_RS07880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IDJ81_RS07895	COG0582	viral genome integration into host DNA
IDJ81_RS07905	COG0741	lytic transglycosylase activity
IDJ81_RS07905	COG1196	nuclear chromosome segregation
IDJ81_RS07905	COG0739	heme binding
IDJ81_RS07920	COG4974	Belongs to the 'phage' integrase family
IDJ81_RS07925	COG4974	Belongs to the 'phage' integrase family
IDJ81_RS07930	COG4974	Belongs to the 'phage' integrase family
IDJ81_RS07940	COG5642	Protein of unknown function (DUF2384)
IDJ81_RS07965	COG4227	nucleotidyltransferase activity
IDJ81_RS08015	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IDJ81_RS08035	COG0577	efflux transmembrane transporter activity
IDJ81_RS08035	COG1136	(ABC) transporter
IDJ81_RS08045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IDJ81_RS08095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IDJ81_RS08125	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IDJ81_RS08250	COG1250	3-hydroxyacyl-CoA dehydrogenase
IDJ81_RS08250	COG1024	Enoyl-CoA hydratase
IDJ81_RS08260	COG1309	transcriptional regulator
IDJ81_RS08265	COG4716	Myosin-crossreactive antigen
IDJ81_RS08330	COG0745	RESPONSE REGULATOR receiver
IDJ81_RS08335	COG5002	protein histidine kinase activity
IDJ81_RS08375	COG1862	Preprotein translocase
IDJ81_RS08380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IDJ81_RS08385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IDJ81_RS08390	COG0438	transferase activity, transferring glycosyl groups
IDJ81_RS08410	COG0488	(ABC) transporter
IDJ81_RS08445	COG0142	geranyltranstransferase activity
IDJ81_RS08450	COG0450	alkyl hydroperoxide reductase
IDJ81_RS08490	COG1476	TRANSCRIPTIONal
IDJ81_RS08495	COG1643	Atp-dependent helicase
IDJ81_RS08515	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IDJ81_RS08520	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IDJ81_RS08555	COG0688	phosphatidylethanolamine metabolic process
IDJ81_RS08575	COG0052	Belongs to the universal ribosomal protein uS2 family
IDJ81_RS08580	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IDJ81_RS08585	COG0528	UMP kinase activity
IDJ81_RS08590	COG0233	cytoplasmic translational termination
IDJ81_RS08595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IDJ81_RS08605	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IDJ81_RS08610	COG0750	zinc metalloprotease
IDJ81_RS08615	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IDJ81_RS08625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IDJ81_RS08630	COG0254	rRNA binding
IDJ81_RS08655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IDJ81_RS08660	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IDJ81_RS08665	COG1138	Cytochrome C-type biogenesis protein
IDJ81_RS08670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IDJ81_RS08675	COG3088	subunit of a heme lyase
IDJ81_RS08685	COG3158	transport of potassium into the cell
IDJ81_RS08690	COG2917	probably involved in intracellular septation
IDJ81_RS08695	COG0552	protein localization to endoplasmic reticulum
IDJ81_RS08700	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IDJ81_RS08705	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IDJ81_RS08710	COG3300	MHYT domain
IDJ81_RS08710	COG5001	Diguanylate cyclase
IDJ81_RS08725	COG0028	Belongs to the TPP enzyme family
IDJ81_RS08740	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IDJ81_RS08750	COG0175	sulfate reduction
IDJ81_RS08760	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IDJ81_RS08770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IDJ81_RS08770	COG1648	precorrin-2 dehydrogenase activity
IDJ81_RS08775	COG0668	transmembrane transport
IDJ81_RS08780	COG0626	cystathionine gamma-synthase activity
IDJ81_RS08795	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IDJ81_RS08830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IDJ81_RS08835	COG1695	Transcriptional regulator
IDJ81_RS08845	COG0438	transferase activity, transferring glycosyl groups
IDJ81_RS08855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IDJ81_RS08860	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IDJ81_RS08880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IDJ81_RS08895	COG1648	precorrin-2 dehydrogenase activity
IDJ81_RS08895	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IDJ81_RS08900	COG0019	diaminopimelate decarboxylase activity
IDJ81_RS08910	COG0165	Argininosuccinate lyase
IDJ81_RS08915	COG3118	belongs to the thioredoxin family
IDJ81_RS08920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IDJ81_RS08930	COG0252	asparaginase activity
IDJ81_RS08945	COG0101	tRNA pseudouridine synthase activity
IDJ81_RS08950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IDJ81_RS08955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IDJ81_RS08960	COG0242	peptide deformylase activity
IDJ81_RS08970	COG1322	Protein conserved in bacteria
IDJ81_RS08980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IDJ81_RS08990	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IDJ81_RS08990	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IDJ81_RS08995	COG1660	Displays ATPase and GTPase activities
IDJ81_RS09005	COG2205	protein histidine kinase activity
IDJ81_RS09010	COG0745	RESPONSE REGULATOR receiver
IDJ81_RS09015	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IDJ81_RS09040	COG2945	thiolester hydrolase activity
IDJ81_RS09045	COG1104	cysteine desulfurase activity
IDJ81_RS09050	COG1104	cysteine desulfurase activity
IDJ81_RS09060	COG0693	protein deglycase activity
IDJ81_RS09065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IDJ81_RS09110	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IDJ81_RS09120	COG0625	glutathione transferase activity
IDJ81_RS09140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IDJ81_RS09150	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IDJ81_RS09155	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
IDJ81_RS09165	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IDJ81_RS09200	COG1970	mechanosensitive ion channel activity
IDJ81_RS09205	COG1970	mechanosensitive ion channel activity
IDJ81_RS09220	COG3724	N-succinylarginine dihydrolase activity
IDJ81_RS09235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IDJ81_RS09240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IDJ81_RS09245	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IDJ81_RS09255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IDJ81_RS09265	COG0105	UTP biosynthetic process
IDJ81_RS09275	COG2133	pyrroloquinoline quinone binding
IDJ81_RS09280	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IDJ81_RS09285	COG2189	Belongs to the N(4) N(6)-methyltransferase family
IDJ81_RS09295	COG3338	carbonate dehydratase activity
IDJ81_RS09355	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IDJ81_RS09375	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IDJ81_RS09390	COG0681	Belongs to the peptidase S26 family
IDJ81_RS09395	COG0736	holo-[acyl-carrier-protein] synthase activity
IDJ81_RS09400	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IDJ81_RS09405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IDJ81_RS09410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IDJ81_RS09415	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IDJ81_RS09420	COG2267	carboxylic ester hydrolase activity
IDJ81_RS09425	COG0109	protoheme IX farnesyltransferase activity
IDJ81_RS09430	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IDJ81_RS09475	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IDJ81_RS09490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IDJ81_RS09500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IDJ81_RS09505	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IDJ81_RS09530	COG1881	PFAM PEBP family protein
IDJ81_RS09555	COG2171	N-acyltransferase activity
IDJ81_RS09560	COG1404	Belongs to the peptidase S8 family
IDJ81_RS09570	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IDJ81_RS09575	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS09580	COG2211	Major facilitator Superfamily
IDJ81_RS09580	COG2211	Major facilitator Superfamily
IDJ81_RS09585	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS09590	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS09605	COG0194	GDP metabolic process
IDJ81_RS09620	COG0131	Imidazoleglycerol-phosphate dehydratase
IDJ81_RS09625	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IDJ81_RS09630	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IDJ81_RS09635	COG0107	imidazoleglycerol-phosphate synthase activity
IDJ81_RS09645	COG0140	phosphoribosyl-ATP diphosphatase activity
IDJ81_RS09655	COG0824	Thioesterase
IDJ81_RS09665	COG0848	biopolymer transport protein
IDJ81_RS09675	COG0823	Involved in the tonB-independent uptake of proteins
IDJ81_RS09680	COG2885	chlorophyll binding
IDJ81_RS09690	COG0484	heat shock protein binding
IDJ81_RS09705	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IDJ81_RS09710	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IDJ81_RS09720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IDJ81_RS09725	COG1045	serine acetyltransferase
IDJ81_RS09735	COG0488	(ABC) transporter
IDJ81_RS09740	COG1028	Short-chain dehydrogenase reductase Sdr
IDJ81_RS09745	COG0546	phosphoglycolate phosphatase activity
IDJ81_RS09750	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IDJ81_RS09765	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IDJ81_RS09770	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IDJ81_RS09775	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IDJ81_RS09780	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IDJ81_RS09785	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IDJ81_RS09795	COG2169	Transcriptional regulator
IDJ81_RS09795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IDJ81_RS09815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IDJ81_RS09820	COG1733	regulation of RNA biosynthetic process
IDJ81_RS09840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IDJ81_RS09860	COG0778	Nitroreductase
IDJ81_RS09860	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
IDJ81_RS09865	COG0215	cysteine-tRNA ligase activity
IDJ81_RS09875	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IDJ81_RS09880	COG0137	argininosuccinate synthase activity
IDJ81_RS09885	COG0534	Mate efflux family protein
IDJ81_RS09890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IDJ81_RS09895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IDJ81_RS09900	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
IDJ81_RS09915	COG2258	MOSC domain
IDJ81_RS09920	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IDJ81_RS09940	COG0741	lytic transglycosylase activity
IDJ81_RS09945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IDJ81_RS09950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IDJ81_RS09975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IDJ81_RS09990	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IDJ81_RS10005	COG0538	isocitrate dehydrogenase activity
IDJ81_RS10030	COG0277	FAD linked oxidase domain protein
IDJ81_RS10040	COG0513	Belongs to the DEAD box helicase family
IDJ81_RS10045	COG0210	DNA helicase
IDJ81_RS10060	COG0742	ribosomal rna small subunit methyltransferase
IDJ81_RS10065	COG1187	pseudouridine synthase activity
IDJ81_RS10080	COG0285	dihydrofolate synthase activity
IDJ81_RS10085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IDJ81_RS10090	COG0159	tryptophan synthase activity
IDJ81_RS10095	COG0133	tryptophan synthase activity
IDJ81_RS10105	COG0135	phosphoribosylanthranilate isomerase activity
IDJ81_RS10115	COG0284	orotidine-5'-phosphate decarboxylase activity
IDJ81_RS10125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IDJ81_RS10145	COG2003	Belongs to the UPF0758 family
IDJ81_RS10170	COG0356	it plays a direct role in the translocation of protons across the membrane
IDJ81_RS10180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IDJ81_RS10185	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IDJ81_RS10190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IDJ81_RS10200	COG0539	negative regulation of cytoplasmic translation
IDJ81_RS10220	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IDJ81_RS10230	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IDJ81_RS10245	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IDJ81_RS10250	COG0228	four-way junction DNA binding
IDJ81_RS10255	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IDJ81_RS10260	COG0336	Belongs to the RNA methyltransferase TrmD family
IDJ81_RS10265	COG0335	large ribosomal subunit rRNA binding
IDJ81_RS10280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IDJ81_RS10285	COG2814	Major facilitator Superfamily
IDJ81_RS10290	COG1566	PFAM secretion protein HlyD family protein
IDJ81_RS10310	COG4067	protein conserved in archaea
IDJ81_RS10310	COG0189	ligase activity
IDJ81_RS10315	COG0189	ligase activity
IDJ81_RS10320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IDJ81_RS10330	COG0359	binds to the 23S rRNA
IDJ81_RS10335	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IDJ81_RS10340	COG0360	Binds together with S18 to 16S ribosomal RNA
IDJ81_RS10345	COG2354	Protein conserved in bacteria
IDJ81_RS10350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IDJ81_RS10355	COG1619	proteins homologs of microcin C7 resistance protein MccF
IDJ81_RS10360	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IDJ81_RS10375	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IDJ81_RS10380	COG0493	'glutamate synthase
IDJ81_RS10390	COG0481	GTPase activity
IDJ81_RS10410	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IDJ81_RS10415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IDJ81_RS10435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IDJ81_RS10440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IDJ81_RS10445	COG0114	fumarate hydratase activity
IDJ81_RS10465	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IDJ81_RS10500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IDJ81_RS10520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IDJ81_RS10525	COG0126	phosphoglycerate kinase activity
IDJ81_RS10535	COG3588	fructose-bisphosphate aldolase
IDJ81_RS10545	COG0352	thiamine-phosphate diphosphorylase activity
IDJ81_RS10555	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IDJ81_RS10560	COG0483	inositol monophosphate 1-phosphatase activity
IDJ81_RS10585	COG0583	DNA-binding transcription factor activity
IDJ81_RS10610	COG0668	transmembrane transport
IDJ81_RS10625	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IDJ81_RS10630	COG0022	dehydrogenase e1 component
IDJ81_RS10630	COG0508	dehydrogenase complex catalyzes the overall conversion of
IDJ81_RS10645	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IDJ81_RS10655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IDJ81_RS10675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IDJ81_RS10685	COG1058	Belongs to the CinA family
IDJ81_RS10685	COG1546	Belongs to the CinA family
IDJ81_RS10695	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IDJ81_RS10695	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IDJ81_RS10705	COG3852	Histidine kinase
IDJ81_RS10715	COG5000	phosphorelay sensor kinase activity
IDJ81_RS10720	COG2204	response regulator
IDJ81_RS10725	COG1923	regulation of RNA biosynthetic process
IDJ81_RS10730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IDJ81_RS10735	COG3956	TIGRFAM MazG family protein
IDJ81_RS10745	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IDJ81_RS10745	COG0321	lipoyl(octanoyl) transferase activity
IDJ81_RS10750	COG0084	hydrolase, TatD family'
IDJ81_RS10760	COG0470	DNA polymerase III
IDJ81_RS10765	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IDJ81_RS10780	COG2951	lytic endotransglycosylase activity
IDJ81_RS10790	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IDJ81_RS10795	COG3590	peptidase
IDJ81_RS10800	COG0148	phosphopyruvate hydratase activity
IDJ81_RS10830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IDJ81_RS10840	COG0505	Belongs to the CarA family
IDJ81_RS10850	COG0358	DNA primase activity
IDJ81_RS10855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IDJ81_RS10870	COG0698	ribose 5-phosphate isomerase
IDJ81_RS10875	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IDJ81_RS10885	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IDJ81_RS10900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IDJ81_RS10905	COG0343	queuine tRNA-ribosyltransferase activity
IDJ81_RS10915	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IDJ81_RS10925	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IDJ81_RS10930	COG0142	geranyltranstransferase activity
IDJ81_RS10935	COG1722	exodeoxyribonuclease VII activity
IDJ81_RS10945	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IDJ81_RS10960	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IDJ81_RS10965	COG0028	Belongs to the TPP enzyme family
IDJ81_RS10975	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IDJ81_RS10980	COG0438	transferase activity, transferring glycosyl groups
IDJ81_RS10985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IDJ81_RS11015	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IDJ81_RS11030	COG5002	protein histidine kinase activity
IDJ81_RS11035	COG0573	inorganic phosphate transmembrane transporter activity
IDJ81_RS11045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IDJ81_RS11050	COG0704	Plays a role in the regulation of phosphate uptake
IDJ81_RS11055	COG0745	RESPONSE REGULATOR receiver
IDJ81_RS11070	COG0531	amino acid
IDJ81_RS11075	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IDJ81_RS11095	COG2204	response regulator
IDJ81_RS11105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IDJ81_RS11115	COG1396	sequence-specific DNA binding
IDJ81_RS11115	COG3800	Transcriptional regulator
IDJ81_RS11130	COG0471	metal ion transport
IDJ81_RS11130	COG3273	potassium ion transport
IDJ81_RS11140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IDJ81_RS11150	COG0071	Belongs to the small heat shock protein (HSP20) family
IDJ81_RS11155	COG0504	CTP synthase activity
IDJ81_RS11165	COG0149	triose-phosphate isomerase activity
IDJ81_RS11170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IDJ81_RS11175	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IDJ81_RS11195	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IDJ81_RS11200	COG0134	indole-3-glycerol-phosphate synthase activity
IDJ81_RS11205	COG0315	cyclic pyranopterin monophosphate synthase activity
IDJ81_RS11210	COG0303	'Molybdopterin
IDJ81_RS11215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IDJ81_RS11220	COG2333	competence protein COMEC
IDJ81_RS11220	COG0658	competence protein
IDJ81_RS11225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IDJ81_RS11230	COG0372	Belongs to the citrate synthase family
IDJ81_RS11235	COG2205	protein histidine kinase activity
IDJ81_RS11270	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IDJ81_RS11280	COG1007	ATP synthesis coupled electron transport
IDJ81_RS11295	COG0713	ATP synthesis coupled electron transport
IDJ81_RS11305	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IDJ81_RS11310	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IDJ81_RS11315	COG1034	ATP synthesis coupled electron transport
IDJ81_RS11320	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IDJ81_RS11330	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IDJ81_RS11340	COG0649	NAD binding
IDJ81_RS11350	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IDJ81_RS11355	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IDJ81_RS11360	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IDJ81_RS11365	COG1012	belongs to the aldehyde dehydrogenase family
IDJ81_RS11370	COG0183	Belongs to the thiolase family
IDJ81_RS11400	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IDJ81_RS11405	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IDJ81_RS11415	COG1530	ribonuclease E activity
IDJ81_RS11420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IDJ81_RS11430	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IDJ81_RS11435	COG1024	Enoyl-CoA hydratase
IDJ81_RS11435	COG1250	3-hydroxyacyl-CoA dehydrogenase
IDJ81_RS11440	COG0367	asparagine synthase
IDJ81_RS11465	COG3267	Type II secretory pathway component ExeA
IDJ81_RS11465	COG3409	Peptidoglycan-binding domain 1 protein
IDJ81_RS11490	COG0019	diaminopimelate decarboxylase activity
IDJ81_RS11495	COG0318	PFAM AMP-dependent synthetase and ligase
IDJ81_RS11520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IDJ81_RS11525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IDJ81_RS11525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IDJ81_RS11535	COG0129	dihydroxy-acid dehydratase activity
IDJ81_RS11545	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IDJ81_RS11565	COG0521	Mo-molybdopterin cofactor biosynthetic process
IDJ81_RS11575	COG1960	acyl-CoA dehydrogenase activity
IDJ81_RS11585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IDJ81_RS11600	COG0574	Belongs to the PEP-utilizing enzyme family
IDJ81_RS11600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IDJ81_RS11605	COG0751	glycine-tRNA ligase activity
IDJ81_RS11610	COG0752	glycyl-tRNA synthetase alpha subunit
IDJ81_RS11635	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IDJ81_RS11640	COG0193	aminoacyl-tRNA hydrolase activity
IDJ81_RS11655	COG2855	membrane
IDJ81_RS11665	COG0012	GTP binding
IDJ81_RS11685	COG1012	belongs to the aldehyde dehydrogenase family
IDJ81_RS11685	COG2030	dehydratase
IDJ81_RS11695	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IDJ81_RS11720	COG0772	Belongs to the SEDS family
IDJ81_RS11730	COG0582	viral genome integration into host DNA
IDJ81_RS11750	COG2948	multi-organism process
IDJ81_RS11765	COG3846	protein secretion by the type IV secretion system
IDJ81_RS11775	COG3451	type IV secretory pathway VirB4
IDJ81_RS11790	COG4962	Type ii secretion system protein e
IDJ81_RS11820	COG0210	DNA helicase
IDJ81_RS11875	COG4227	nucleotidyltransferase activity
IDJ81_RS11895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IDJ81_RS11925	COG0110	maltose O-acetyltransferase activity
IDJ81_RS11930	COG3433	isochorismatase activity
IDJ81_RS11930	COG1535	isochorismatase
IDJ81_RS11945	COG1280	lysine exporter protein (LysE YggA)
IDJ81_RS11985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IDJ81_RS12000	COG0508	dehydrogenase complex catalyzes the overall conversion of
IDJ81_RS12010	COG0557	exoribonuclease II activity
IDJ81_RS12015	COG2234	aminopeptidase activity
IDJ81_RS12025	COG0442	prolyl-tRNA aminoacylation
IDJ81_RS12035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IDJ81_RS12060	COG1752	Esterase of the alpha-beta hydrolase superfamily
IDJ81_RS12065	COG0484	heat shock protein binding
IDJ81_RS12070	COG0443	Heat shock 70 kDa protein
IDJ81_RS12095	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IDJ81_RS12100	COG1420	regulation of RNA biosynthetic process
IDJ81_RS12105	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IDJ81_RS12110	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IDJ81_RS12120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IDJ81_RS12125	COG4974	Belongs to the 'phage' integrase family
IDJ81_RS12130	COG0586	Pfam SNARE associated Golgi protein
IDJ81_RS12135	COG0189	ligase activity
IDJ81_RS12140	COG0792	nuclease activity
IDJ81_RS12145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IDJ81_RS12155	COG0187	DNA topoisomerase II activity
IDJ81_RS12170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IDJ81_RS12175	COG3739	integral membrane protein
IDJ81_RS12185	COG3876	Protein conserved in bacteria
IDJ81_RS12195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IDJ81_RS12225	COG0318	PFAM AMP-dependent synthetase and ligase
IDJ81_RS12235	COG0386	Belongs to the glutathione peroxidase family
IDJ81_RS12240	COG1136	(ABC) transporter
IDJ81_RS12245	COG4591	ABC-type transport system involved in lipoprotein release permease component
IDJ81_RS12250	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IDJ81_RS12255	COG4221	oxidoreductase activity
IDJ81_RS12270	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IDJ81_RS12275	COG0415	Belongs to the DNA photolyase family
IDJ81_RS12280	COG0671	phosphoesterase, PA-phosphatase related
IDJ81_RS12285	COG1013	pyruvate-flavodoxin oxidoreductase activity
IDJ81_RS12290	COG0674	pyruvate-flavodoxin oxidoreductase activity
IDJ81_RS12290	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
IDJ81_RS12295	COG0657	acetylesterase activity
IDJ81_RS12300	COG1051	belongs to the nudix hydrolase family
IDJ81_RS12310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IDJ81_RS12310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IDJ81_RS12330	COG1028	Short-chain dehydrogenase reductase Sdr
IDJ81_RS12335	COG2321	neutral zinc metallopeptidase
IDJ81_RS12355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IDJ81_RS12370	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IDJ81_RS12390	COG2264	protein methyltransferase activity
IDJ81_RS12405	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IDJ81_RS12425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IDJ81_RS12440	COG0730	response to heat
IDJ81_RS12445	COG0653	protein targeting
IDJ81_RS12455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IDJ81_RS12470	COG1074	ATP-dependent DNA helicase activity
IDJ81_RS12475	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IDJ81_RS12480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IDJ81_RS12485	COG3178	'Phosphotransferase
IDJ81_RS12490	COG0802	atpase or kinase
IDJ81_RS12495	COG2205	protein histidine kinase activity
IDJ81_RS12500	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IDJ81_RS12505	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IDJ81_RS12505	COG0678	peroxiredoxin activity
IDJ81_RS12510	COG0302	gtp cyclohydrolase
IDJ81_RS12525	COG0494	nUDIX hydrolase
IDJ81_RS12545	COG0825	malonyl-CoA metabolic process
IDJ81_RS12550	COG4974	Belongs to the 'phage' integrase family
IDJ81_RS12560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IDJ81_RS12565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IDJ81_RS12570	COG3104	oligopeptide transport
IDJ81_RS12575	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IDJ81_RS12580	COG0668	transmembrane transport
IDJ81_RS12590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IDJ81_RS12595	COG4770	biotin carboxylase activity
IDJ81_RS12605	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IDJ81_RS12610	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IDJ81_RS12610	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IDJ81_RS12615	COG0346	lactoylglutathione lyase activity
IDJ81_RS12620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IDJ81_RS12625	COG1396	sequence-specific DNA binding
IDJ81_RS12625	COG3800	Transcriptional regulator
IDJ81_RS12635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IDJ81_RS12645	COG0513	Belongs to the DEAD box helicase family
IDJ81_RS12650	COG0166	Belongs to the GPI family
IDJ81_RS12660	COG0571	ribonuclease III activity
IDJ81_RS12665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IDJ81_RS12675	COG1754	DNA topoisomerase type I activity
IDJ81_RS12675	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IDJ81_RS12685	COG0758	DNA mediated transformation
IDJ81_RS12690	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IDJ81_RS12695	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IDJ81_RS12700	COG0156	8-amino-7-oxononanoate synthase activity
IDJ81_RS12705	COG3300	MHYT domain
IDJ81_RS12705	COG5001	Diguanylate cyclase
IDJ81_RS12745	COG2226	methyltransferase
IDJ81_RS12770	COG0492	ferredoxin-NADP+ reductase activity
IDJ81_RS12780	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IDJ81_RS12785	COG3387	PFAM Glycoside hydrolase 15-related
IDJ81_RS12790	COG1877	trehalose-phosphatase activity
IDJ81_RS12800	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IDJ81_RS12805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IDJ81_RS12810	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IDJ81_RS12815	COG0612	Peptidase, M16
IDJ81_RS12820	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IDJ81_RS12840	COG4957	zinc ion binding
IDJ81_RS12855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IDJ81_RS12885	COG1024	Enoyl-CoA hydratase
IDJ81_RS12900	COG0583	DNA-binding transcription factor activity
IDJ81_RS12905	COG2030	dehydratase
IDJ81_RS12970	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IDJ81_RS12990	COG0408	coproporphyrinogen oxidase activity
IDJ81_RS13000	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IDJ81_RS13010	COG0471	metal ion transport
IDJ81_RS13025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IDJ81_RS13050	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IDJ81_RS13070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IDJ81_RS13080	COG0028	Belongs to the TPP enzyme family
IDJ81_RS13090	COG0339	signal peptide processing
IDJ81_RS13095	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IDJ81_RS13110	COG4206	TonB-dependent receptor
IDJ81_RS13125	COG3300	MHYT domain
IDJ81_RS13125	COG5001	Diguanylate cyclase
IDJ81_RS13130	COG0039	L-malate dehydrogenase activity
IDJ81_RS13135	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IDJ81_RS13145	COG0567	Dehydrogenase, E1 component
IDJ81_RS13150	COG0508	dehydrogenase complex catalyzes the overall conversion of
IDJ81_RS13155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IDJ81_RS13170	COG2860	membrane
IDJ81_RS13185	COG0203	ribosomal protein L17
IDJ81_RS13190	COG0202	RNA polymerase activity
IDJ81_RS13195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IDJ81_RS13200	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IDJ81_RS13210	COG0563	adenylate kinase activity
IDJ81_RS13215	COG0201	protein transport
IDJ81_RS13220	COG0200	Binds to the 23S rRNA
IDJ81_RS13225	COG1841	ribosomal large subunit assembly
IDJ81_RS13230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IDJ81_RS13235	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IDJ81_RS13240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IDJ81_RS13245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IDJ81_RS13250	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IDJ81_RS13255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IDJ81_RS13260	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IDJ81_RS13265	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IDJ81_RS13270	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IDJ81_RS13275	COG0255	Belongs to the universal ribosomal protein uL29 family
IDJ81_RS13280	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IDJ81_RS13285	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IDJ81_RS13290	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IDJ81_RS13295	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IDJ81_RS13300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IDJ81_RS13305	COG0089	rRNA binding
IDJ81_RS13310	COG0088	Forms part of the polypeptide exit tunnel
IDJ81_RS13315	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IDJ81_RS13320	COG0051	transcription antitermination factor activity, RNA binding
IDJ81_RS13325	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IDJ81_RS13330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IDJ81_RS13335	COG0049	tRNA binding
IDJ81_RS13340	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IDJ81_RS13350	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IDJ81_RS13360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IDJ81_RS13365	COG0776	regulation of translation
IDJ81_RS13375	COG1218	3'(2'),5'-bisphosphate nucleotidase
IDJ81_RS13380	COG0529	Catalyzes the synthesis of activated sulfate
IDJ81_RS13380	COG2895	sulfate adenylyltransferase (ATP) activity
IDJ81_RS13385	COG0175	sulfate reduction
IDJ81_RS13405	COG0583	DNA-binding transcription factor activity
IDJ81_RS13425	COG4773	Receptor
IDJ81_RS13440	COG1278	Cold shock
IDJ81_RS13450	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IDJ81_RS13460	COG2204	response regulator
IDJ81_RS13485	COG0297	glycogen (starch) synthase activity
IDJ81_RS13490	COG1215	transferase activity, transferring glycosyl groups
IDJ81_RS13495	COG1216	Glycosyl transferase, family 2
IDJ81_RS13500	COG2244	polysaccharide biosynthetic process
IDJ81_RS13505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IDJ81_RS13510	COG4999	Histidine kinase
IDJ81_RS13510	COG3850	Histidine kinase
IDJ81_RS13510	COG3437	response regulator, receiver
IDJ81_RS13510	COG2205	protein histidine kinase activity
IDJ81_RS13515	COG0784	Response regulator, receiver
IDJ81_RS13515	COG2205	protein histidine kinase activity
IDJ81_RS13525	COG0745	RESPONSE REGULATOR receiver
IDJ81_RS13530	COG2205	protein histidine kinase activity
IDJ81_RS13535	COG3158	transport of potassium into the cell
IDJ81_RS13565	COG3152	Membrane
IDJ81_RS13595	COG3451	type IV secretory pathway VirB4
IDJ81_RS13605	COG3736	Type IV secretory pathway, component VirB8
IDJ81_RS13615	COG2948	multi-organism process
IDJ81_RS13620	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
IDJ81_RS13700	COG3152	Membrane
IDJ81_RS13780	COG0436	Aminotransferase
IDJ81_RS13785	COG3243	poly(R)-hydroxyalkanoic acid synthase
IDJ81_RS13795	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IDJ81_RS13820	COG2201	protein-glutamate methylesterase activity
IDJ81_RS13830	COG0784	Response regulator, receiver
IDJ81_RS13835	COG3920	Histidine kinase
IDJ81_RS13865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IDJ81_RS13875	COG0351	phosphomethylpyrimidine kinase
IDJ81_RS13895	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IDJ81_RS13900	COG3474	cytochrome
IDJ81_RS13920	COG0714	Associated with various cellular activities
IDJ81_RS13940	COG0454	-acetyltransferase
IDJ81_RS13945	COG2367	Beta-lactamase
IDJ81_RS13955	COG0583	DNA-binding transcription factor activity
IDJ81_RS13975	COG2311	Membrane
IDJ81_RS14000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IDJ81_RS14005	COG0540	Belongs to the ATCase OTCase family
IDJ81_RS14010	COG0616	signal peptide processing
IDJ81_RS14035	COG0745	RESPONSE REGULATOR receiver
IDJ81_RS14040	COG2205	protein histidine kinase activity
IDJ81_RS14040	COG0784	Response regulator, receiver
IDJ81_RS14050	COG0446	pyridine nucleotide-disulphide oxidoreductase
IDJ81_RS14080	COG1609	Transcriptional regulator
IDJ81_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
IDJ81_RS14100	COG2272	Belongs to the type-B carboxylesterase lipase family
IDJ81_RS14130	COG3507	Belongs to the glycosyl hydrolase 43 family
IDJ81_RS14135	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IDJ81_RS14150	COG2721	sulfolactate sulfo-lyase activity
IDJ81_RS14155	COG1904	glucuronate isomerase
IDJ81_RS14160	COG0246	Mannitol dehydrogenase
IDJ81_RS14175	COG4771	TonB-dependent receptor
IDJ81_RS14180	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
IDJ81_RS14200	COG3451	type IV secretory pathway VirB4
IDJ81_RS14215	COG0741	lytic transglycosylase activity
IDJ81_RS14215	COG1196	nuclear chromosome segregation
IDJ81_RS14215	COG0739	heme binding
IDJ81_RS14230	COG4772	TonB-dependent receptor
IDJ81_RS14235	COG0745	RESPONSE REGULATOR receiver
IDJ81_RS14265	COG0800	Aldolase
IDJ81_RS14270	COG0837	glucose binding
IDJ81_RS14275	COG0129	dihydroxy-acid dehydratase activity
IDJ81_RS14280	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IDJ81_RS14285	COG0432	Pfam Uncharacterised protein family UPF0047
IDJ81_RS14300	COG0418	dihydroorotase activity
IDJ81_RS14305	COG0354	folic acid binding
IDJ81_RS14320	COG3153	acetyltransferase
IDJ81_RS14320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IDJ81_RS14335	COG1278	Cold shock
IDJ81_RS14350	COG2824	Alkylphosphonate utilization operon protein PhnA
IDJ81_RS14360	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IDJ81_RS14410	COG2814	Major facilitator Superfamily
IDJ81_RS14420	COG1051	belongs to the nudix hydrolase family
IDJ81_RS14430	COG0783	Belongs to the Dps family
IDJ81_RS14445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IDJ81_RS14450	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IDJ81_RS14475	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IDJ81_RS14475	COG0546	phosphoglycolate phosphatase activity
IDJ81_RS14495	COG2076	Multidrug Resistance protein
IDJ81_RS14505	COG1609	Transcriptional regulator
IDJ81_RS14510	COG1472	Belongs to the glycosyl hydrolase 3 family
IDJ81_RS14515	COG4771	TonB-dependent receptor
IDJ81_RS14525	COG4771	TonB-dependent receptor
IDJ81_RS14530	COG2365	Tyrosine phosphatase family
IDJ81_RS14540	COG1024	Enoyl-CoA hydratase
IDJ81_RS14540	COG1250	3-hydroxyacyl-CoA dehydrogenase
IDJ81_RS14580	COG1028	Short-chain dehydrogenase reductase Sdr
IDJ81_RS14585	COG1024	Enoyl-CoA hydratase
IDJ81_RS14600	COG0183	Belongs to the thiolase family
IDJ81_RS14605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IDJ81_RS14620	COG1028	Short-chain dehydrogenase reductase Sdr
IDJ81_RS14645	COG4771	TonB-dependent receptor
IDJ81_RS14690	COG0805	protein transport
IDJ81_RS14695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IDJ81_RS14700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IDJ81_RS14705	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IDJ81_RS14710	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IDJ81_RS14715	COG1472	Belongs to the glycosyl hydrolase 3 family
IDJ81_RS14725	COG0018	arginyl-trna synthetase
IDJ81_RS14735	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IDJ81_RS14740	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IDJ81_RS14745	COG0328	RNA-DNA hybrid ribonuclease activity
IDJ81_RS14750	COG3422	double-strand break repair
IDJ81_RS14775	COG4964	Belongs to the GSP D family
IDJ81_RS14805	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IDJ81_RS14810	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IDJ81_RS14820	COG0183	Belongs to the thiolase family
IDJ81_RS14825	COG4771	TonB-dependent receptor
IDJ81_RS14835	COG0457	Tetratricopeptide repeat
IDJ81_RS14850	COG4206	TonB-dependent receptor
IDJ81_RS14855	COG0542	response to heat
IDJ81_RS14860	COG0612	Peptidase, M16
IDJ81_RS14870	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IDJ81_RS14875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IDJ81_RS14885	COG0154	amidase activity
IDJ81_RS14890	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IDJ81_RS14905	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IDJ81_RS14910	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IDJ81_RS14925	COG0546	phosphoglycolate phosphatase activity
IDJ81_RS14950	COG1127	ABC transporter
IDJ81_RS14955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IDJ81_RS14960	COG0525	valine-tRNA ligase activity
IDJ81_RS14970	COG0534	Mate efflux family protein
IDJ81_RS14985	COG0730	response to heat
IDJ81_RS15000	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IDJ81_RS15020	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IDJ81_RS15035	COG3023	N-Acetylmuramoyl-L-alanine amidase
IDJ81_RS15060	COG0564	pseudouridine synthase activity
IDJ81_RS15065	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IDJ81_RS15085	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IDJ81_RS15090	COG0740	serine-type endopeptidase activity
IDJ81_RS15105	COG0544	peptidyl-prolyl cis-trans isomerase activity
IDJ81_RS15130	COG1160	GTP binding
IDJ81_RS15145	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IDJ81_RS15160	COG2989	Protein conserved in bacteria
IDJ81_RS15170	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IDJ81_RS15185	COG2255	four-way junction helicase activity
IDJ81_RS15195	COG0632	four-way junction helicase activity
IDJ81_RS15210	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IDJ81_RS15215	COG0450	alkyl hydroperoxide reductase
IDJ81_RS15225	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
IDJ81_RS15230	COG1054	Belongs to the UPF0176 family
IDJ81_RS15250	COG4395	Tim44
IDJ81_RS15255	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IDJ81_RS15265	COG0180	Tryptophanyl-tRNA synthetase
IDJ81_RS15280	COG0756	dUTP diphosphatase activity
IDJ81_RS15285	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IDJ81_RS15300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IDJ81_RS15305	COG2226	methyltransferase
IDJ81_RS15310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IDJ81_RS15315	COG0268	Binds directly to 16S ribosomal RNA