locus-tag	class	description
CJO11_RS00015	COG1538	Outer membrane efflux protein
CJO11_RS00050	COG2080	2 iron, 2 sulfur cluster binding
CJO11_RS00055	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
CJO11_RS00060	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CJO11_RS00105	COG0114	fumarate hydratase activity
CJO11_RS00120	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CJO11_RS00150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CJO11_RS00165	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CJO11_RS00170	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CJO11_RS00175	COG0126	phosphoglycerate kinase activity
CJO11_RS00185	COG3588	fructose-bisphosphate aldolase
CJO11_RS00190	COG0352	thiamine-phosphate diphosphorylase activity
CJO11_RS00195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CJO11_RS00200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CJO11_RS00205	COG1420	regulation of RNA biosynthetic process
CJO11_RS00210	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CJO11_RS00235	COG0443	Heat shock 70 kDa protein
CJO11_RS00240	COG0484	heat shock protein binding
CJO11_RS00245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJO11_RS00255	COG1752	Esterase of the alpha-beta hydrolase superfamily
CJO11_RS00280	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJO11_RS00290	COG0442	prolyl-tRNA aminoacylation
CJO11_RS00300	COG0557	exoribonuclease II activity
CJO11_RS00310	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO11_RS00325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJO11_RS00335	COG0772	Belongs to the SEDS family
CJO11_RS00340	COG0768	penicillin binding
CJO11_RS00360	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CJO11_RS00375	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJO11_RS00385	COG2030	dehydratase
CJO11_RS00390	COG0012	GTP binding
CJO11_RS00400	COG2827	Endonuclease containing a URI domain
CJO11_RS00405	COG0193	aminoacyl-tRNA hydrolase activity
CJO11_RS00410	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CJO11_RS00435	COG0752	glycyl-tRNA synthetase alpha subunit
CJO11_RS00440	COG0751	glycine-tRNA ligase activity
CJO11_RS00445	COG0574	Belongs to the PEP-utilizing enzyme family
CJO11_RS00445	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CJO11_RS00460	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CJO11_RS00465	COG0789	Transcriptional regulator
CJO11_RS00470	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS00495	COG0521	Mo-molybdopterin cofactor biosynthetic process
CJO11_RS00520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CJO11_RS00530	COG0129	dihydroxy-acid dehydratase activity
CJO11_RS00540	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CJO11_RS00540	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CJO11_RS00545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CJO11_RS00575	COG0019	diaminopimelate decarboxylase activity
CJO11_RS00600	COG3409	Peptidoglycan-binding domain 1 protein
CJO11_RS00600	COG3267	Type II secretory pathway component ExeA
CJO11_RS00605	COG0726	polysaccharide deacetylase
CJO11_RS00625	COG0367	asparagine synthase
CJO11_RS00630	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO11_RS00630	COG1024	Enoyl-CoA hydratase
CJO11_RS00645	COG0393	Putative heavy-metal-binding
CJO11_RS00650	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CJO11_RS00660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJO11_RS00665	COG2226	methyltransferase
CJO11_RS00670	COG1530	ribonuclease E activity
CJO11_RS00680	COG0860	N-Acetylmuramoyl-L-alanine amidase
CJO11_RS00685	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CJO11_RS00690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CJO11_RS00710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CJO11_RS00720	COG1215	transferase activity, transferring glycosyl groups
CJO11_RS00725	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CJO11_RS00740	COG0028	Belongs to the TPP enzyme family
CJO11_RS00745	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CJO11_RS00750	COG0560	Phosphoserine phosphatase
CJO11_RS00765	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJO11_RS00780	COG1722	exodeoxyribonuclease VII activity
CJO11_RS00785	COG0142	geranyltranstransferase activity
CJO11_RS00790	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CJO11_RS00800	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CJO11_RS00805	COG1131	(ABC) transporter
CJO11_RS00810	COG0842	Transport permease protein
CJO11_RS00820	COG0343	queuine tRNA-ribosyltransferase activity
CJO11_RS00835	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CJO11_RS00850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CJO11_RS00860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CJO11_RS00865	COG0698	ribose 5-phosphate isomerase
CJO11_RS00875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJO11_RS00880	COG0358	DNA primase activity
CJO11_RS00885	COG2827	Endonuclease containing a URI domain
CJO11_RS00895	COG0505	Belongs to the CarA family
CJO11_RS00910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CJO11_RS00945	COG0148	phosphopyruvate hydratase activity
CJO11_RS00950	COG3590	peptidase
CJO11_RS00965	COG0667	Aldo Keto reductase
CJO11_RS00975	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CJO11_RS00985	COG2951	lytic endotransglycosylase activity
CJO11_RS00995	COG1686	Belongs to the peptidase S11 family
CJO11_RS01000	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CJO11_RS01005	COG0470	DNA polymerase III
CJO11_RS01015	COG0084	hydrolase, TatD family'
CJO11_RS01020	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CJO11_RS01020	COG0321	lipoyl(octanoyl) transferase activity
CJO11_RS01025	COG3956	TIGRFAM MazG family protein
CJO11_RS01030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CJO11_RS01040	COG2204	response regulator
CJO11_RS01045	COG5000	phosphorelay sensor kinase activity
CJO11_RS01050	COG2204	response regulator
CJO11_RS01055	COG3852	Histidine kinase
CJO11_RS01065	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CJO11_RS01065	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CJO11_RS01070	COG1546	Belongs to the CinA family
CJO11_RS01080	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CJO11_RS01100	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJO11_RS01115	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CJO11_RS01160	COG0022	dehydrogenase e1 component
CJO11_RS01160	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO11_RS01165	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CJO11_RS01190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJO11_RS01200	COG0071	Belongs to the small heat shock protein (HSP20) family
CJO11_RS01205	COG0504	CTP synthase activity
CJO11_RS01215	COG0149	triose-phosphate isomerase activity
CJO11_RS01225	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CJO11_RS01250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJO11_RS01255	COG0134	indole-3-glycerol-phosphate synthase activity
CJO11_RS01260	COG0315	cyclic pyranopterin monophosphate synthase activity
CJO11_RS01265	COG0303	'Molybdopterin
CJO11_RS01270	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CJO11_RS01275	COG0658	competence protein
CJO11_RS01275	COG2333	competence protein COMEC
CJO11_RS01280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJO11_RS01285	COG0372	Belongs to the citrate synthase family
CJO11_RS01295	COG2205	protein histidine kinase activity
CJO11_RS01330	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CJO11_RS01340	COG1007	ATP synthesis coupled electron transport
CJO11_RS01355	COG0713	ATP synthesis coupled electron transport
CJO11_RS01365	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJO11_RS01370	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CJO11_RS01380	COG1034	ATP synthesis coupled electron transport
CJO11_RS01395	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
CJO11_RS01400	COG0649	NAD binding
CJO11_RS01405	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJO11_RS01410	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJO11_RS01415	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CJO11_RS01420	COG1012	belongs to the aldehyde dehydrogenase family
CJO11_RS01425	COG0183	Belongs to the thiolase family
CJO11_RS01445	COG3618	amidohydrolase
CJO11_RS01470	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CJO11_RS01490	COG5002	protein histidine kinase activity
CJO11_RS01495	COG0704	Plays a role in the regulation of phosphate uptake
CJO11_RS01500	COG0745	RESPONSE REGULATOR receiver
CJO11_RS01510	COG1280	lysine exporter protein (LysE YggA)
CJO11_RS01535	COG0531	amino acid
CJO11_RS01540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CJO11_RS01550	COG0385	Bile acid
CJO11_RS01560	COG2204	response regulator
CJO11_RS01570	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJO11_RS01575	COG1396	sequence-specific DNA binding
CJO11_RS01575	COG3800	Transcriptional regulator
CJO11_RS01600	COG0483	inositol monophosphate 1-phosphatase activity
CJO11_RS01605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CJO11_RS01615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJO11_RS01620	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CJO11_RS01625	COG0189	ligase activity
CJO11_RS01630	COG0792	nuclease activity
CJO11_RS01635	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CJO11_RS01645	COG0187	DNA topoisomerase II activity
CJO11_RS01660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJO11_RS01670	COG0840	transmembrane signaling receptor activity
CJO11_RS01675	COG3739	integral membrane protein
CJO11_RS01685	COG2814	Major facilitator Superfamily
CJO11_RS01690	COG3384	dioxygenase
CJO11_RS01695	COG3876	Protein conserved in bacteria
CJO11_RS01705	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CJO11_RS01735	COG0318	PFAM AMP-dependent synthetase and ligase
CJO11_RS01745	COG0386	Belongs to the glutathione peroxidase family
CJO11_RS01755	COG1136	(ABC) transporter
CJO11_RS01765	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CJO11_RS01770	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS01785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CJO11_RS01790	COG0415	Belongs to the DNA photolyase family
CJO11_RS01795	COG1013	pyruvate-flavodoxin oxidoreductase activity
CJO11_RS01800	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CJO11_RS01800	COG0674	pyruvate-flavodoxin oxidoreductase activity
CJO11_RS01805	COG0657	acetylesterase activity
CJO11_RS01810	COG1051	belongs to the nudix hydrolase family
CJO11_RS01835	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS01840	COG2321	neutral zinc metallopeptidase
CJO11_RS01850	COG3682	Transcriptional regulator
CJO11_RS01860	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CJO11_RS01870	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CJO11_RS01885	COG2264	protein methyltransferase activity
CJO11_RS01890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CJO11_RS01915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CJO11_RS01925	COG0730	response to heat
CJO11_RS01930	COG0456	acetyltransferase
CJO11_RS01935	COG0653	protein targeting
CJO11_RS01945	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CJO11_RS01950	COG0483	inositol monophosphate 1-phosphatase activity
CJO11_RS01960	COG1074	ATP-dependent DNA helicase activity
CJO11_RS01965	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CJO11_RS01970	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CJO11_RS01975	COG3178	'Phosphotransferase
CJO11_RS01980	COG0802	atpase or kinase
CJO11_RS01985	COG2205	protein histidine kinase activity
CJO11_RS01990	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CJO11_RS02000	COG0678	peroxiredoxin activity
CJO11_RS02000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CJO11_RS02010	COG0302	gtp cyclohydrolase
CJO11_RS02020	COG0494	nUDIX hydrolase
CJO11_RS02040	COG0825	malonyl-CoA metabolic process
CJO11_RS02045	COG4974	Belongs to the 'phage' integrase family
CJO11_RS02055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CJO11_RS02060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CJO11_RS02070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CJO11_RS02075	COG4770	biotin carboxylase activity
CJO11_RS02085	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CJO11_RS02095	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJO11_RS02095	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CJO11_RS02100	COG0346	lactoylglutathione lyase activity
CJO11_RS02110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CJO11_RS02115	COG1396	sequence-specific DNA binding
CJO11_RS02115	COG3800	Transcriptional regulator
CJO11_RS02125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO11_RS02140	COG0513	Belongs to the DEAD box helicase family
CJO11_RS02145	COG0166	Belongs to the GPI family
CJO11_RS02150	COG0571	ribonuclease III activity
CJO11_RS02155	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CJO11_RS02165	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CJO11_RS02165	COG1754	DNA topoisomerase type I activity
CJO11_RS02175	COG0758	DNA mediated transformation
CJO11_RS02180	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CJO11_RS02185	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CJO11_RS02195	COG0156	8-amino-7-oxononanoate synthase activity
CJO11_RS02200	COG2175	clavaminate synthase activity
CJO11_RS02205	COG5001	Diguanylate cyclase
CJO11_RS02235	COG3706	GGDEF domain
CJO11_RS02255	COG1748	Saccharopine dehydrogenase
CJO11_RS02275	COG0492	ferredoxin-NADP+ reductase activity
CJO11_RS02295	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CJO11_RS02305	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
CJO11_RS02315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
CJO11_RS02325	COG1214	PFAM Peptidase M22, glycoprotease
CJO11_RS02325	COG0456	acetyltransferase
CJO11_RS02345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJO11_RS02365	COG1024	Enoyl-CoA hydratase
CJO11_RS02370	COG1024	Enoyl-CoA hydratase
CJO11_RS02375	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS02390	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CJO11_RS02405	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CJO11_RS02410	COG5002	protein histidine kinase activity
CJO11_RS02410	COG0784	Response regulator, receiver
CJO11_RS02410	COG2198	Histidine kinase
CJO11_RS02415	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CJO11_RS02440	COG0481	GTPase activity
CJO11_RS02445	COG5001	Diguanylate cyclase
CJO11_RS02445	COG3300	MHYT domain
CJO11_RS02450	COG3300	MHYT domain
CJO11_RS02450	COG5001	Diguanylate cyclase
CJO11_RS02465	COG0493	'glutamate synthase
CJO11_RS02470	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CJO11_RS02475	COG0604	alcohol dehydrogenase
CJO11_RS02475	COG3321	synthase
CJO11_RS02475	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS02500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CJO11_RS02510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJO11_RS02515	COG0625	glutathione transferase activity
CJO11_RS02520	COG0360	Binds together with S18 to 16S ribosomal RNA
CJO11_RS02525	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CJO11_RS02530	COG0359	binds to the 23S rRNA
CJO11_RS02535	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CJO11_RS02545	COG0189	ligase activity
CJO11_RS02550	COG0189	ligase activity
CJO11_RS02550	COG4067	protein conserved in archaea
CJO11_RS02570	COG1566	PFAM secretion protein HlyD family protein
CJO11_RS02575	COG2814	Major facilitator Superfamily
CJO11_RS02585	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CJO11_RS02595	COG0531	amino acid
CJO11_RS02605	COG0335	large ribosomal subunit rRNA binding
CJO11_RS02610	COG0336	Belongs to the RNA methyltransferase TrmD family
CJO11_RS02615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CJO11_RS02620	COG0228	four-way junction DNA binding
CJO11_RS02625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CJO11_RS02640	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CJO11_RS02650	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CJO11_RS02660	COG0539	negative regulation of cytoplasmic translation
CJO11_RS02665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO11_RS02675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CJO11_RS02680	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CJO11_RS02685	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJO11_RS02690	COG0356	it plays a direct role in the translocation of protons across the membrane
CJO11_RS02715	COG2003	Belongs to the UPF0758 family
CJO11_RS02730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CJO11_RS02740	COG0284	orotidine-5'-phosphate decarboxylase activity
CJO11_RS02750	COG0135	phosphoribosylanthranilate isomerase activity
CJO11_RS02755	COG0133	tryptophan synthase activity
CJO11_RS02765	COG0159	tryptophan synthase activity
CJO11_RS02770	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CJO11_RS02775	COG0285	dihydrofolate synthase activity
CJO11_RS02790	COG1187	pseudouridine synthase activity
CJO11_RS02795	COG0742	ribosomal rna small subunit methyltransferase
CJO11_RS02805	COG0210	DNA helicase
CJO11_RS02810	COG2885	chlorophyll binding
CJO11_RS02825	COG0248	Ppx GppA phosphatase
CJO11_RS02830	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CJO11_RS02855	COG0714	Associated with various cellular activities
CJO11_RS02880	COG0454	-acetyltransferase
CJO11_RS02890	COG1446	asparaginase
CJO11_RS02900	COG4221	oxidoreductase activity
CJO11_RS02910	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CJO11_RS02925	COG2989	Protein conserved in bacteria
CJO11_RS02935	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CJO11_RS02940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO11_RS02955	COG2255	four-way junction helicase activity
CJO11_RS02965	COG0632	four-way junction helicase activity
CJO11_RS02970	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CJO11_RS02975	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
CJO11_RS02980	COG1054	Belongs to the UPF0176 family
CJO11_RS03000	COG4395	Tim44
CJO11_RS03005	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CJO11_RS03015	COG0180	Tryptophanyl-tRNA synthetase
CJO11_RS03030	COG0756	dUTP diphosphatase activity
CJO11_RS03035	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CJO11_RS03045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CJO11_RS03050	COG2226	methyltransferase
CJO11_RS03055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CJO11_RS03060	COG0268	Binds directly to 16S ribosomal RNA
CJO11_RS03065	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJO11_RS03080	COG0531	amino acid
CJO11_RS03085	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CJO11_RS03090	COG2267	carboxylic ester hydrolase activity
CJO11_RS03095	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CJO11_RS03110	COG0584	glycerophosphoryl diester phosphodiesterase
CJO11_RS03125	COG1393	Belongs to the ArsC family
CJO11_RS03135	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CJO11_RS03145	COG0217	transcriptional regulatory protein
CJO11_RS03155	COG1247	-acetyltransferase
CJO11_RS03160	COG3750	Belongs to the UPF0335 family
CJO11_RS03170	COG0469	pyruvate kinase activity
CJO11_RS03180	COG4993	Dehydrogenase
CJO11_RS03180	COG2010	Cytochrome c
CJO11_RS03190	COG0330	HflC and HflK could
CJO11_RS03230	COG0142	geranyltranstransferase activity
CJO11_RS03300	COG1271	oxidase subunit
CJO11_RS03305	COG1294	oxidase, subunit
CJO11_RS03325	COG0408	coproporphyrinogen oxidase activity
CJO11_RS03335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CJO11_RS03340	COG0471	metal ion transport
CJO11_RS03350	COG2234	aminopeptidase activity
CJO11_RS03355	COG0484	heat shock protein binding
CJO11_RS03365	COG2885	chlorophyll binding
CJO11_RS03370	COG0823	Involved in the tonB-independent uptake of proteins
CJO11_RS03380	COG0848	biopolymer transport protein
CJO11_RS03390	COG0824	Thioesterase
CJO11_RS03400	COG0140	phosphoribosyl-ATP diphosphatase activity
CJO11_RS03410	COG0107	imidazoleglycerol-phosphate synthase activity
CJO11_RS03415	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CJO11_RS03420	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CJO11_RS03425	COG0131	Imidazoleglycerol-phosphate dehydratase
CJO11_RS03440	COG0194	GDP metabolic process
CJO11_RS03475	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS03480	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS03485	COG2211	Major facilitator Superfamily
CJO11_RS03490	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS03495	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CJO11_RS03510	COG2171	N-acyltransferase activity
CJO11_RS03540	COG1881	PFAM PEBP family protein
CJO11_RS03565	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CJO11_RS03570	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CJO11_RS03590	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CJO11_RS03630	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CJO11_RS03635	COG0109	protoheme IX farnesyltransferase activity
CJO11_RS03640	COG0596	Alpha beta hydrolase
CJO11_RS03645	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CJO11_RS03650	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CJO11_RS03655	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CJO11_RS03660	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CJO11_RS03665	COG0736	holo-[acyl-carrier-protein] synthase activity
CJO11_RS03670	COG0681	Belongs to the peptidase S26 family
CJO11_RS03675	COG0628	permease
CJO11_RS03685	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CJO11_RS03705	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CJO11_RS03750	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS03755	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CJO11_RS03770	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CJO11_RS03775	COG2272	Belongs to the type-B carboxylesterase lipase family
CJO11_RS03785	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJO11_RS03790	COG2133	pyrroloquinoline quinone binding
CJO11_RS03800	COG0667	Aldo Keto reductase
CJO11_RS03820	COG0617	tRNA 3'-terminal CCA addition
CJO11_RS03830	COG0252	asparaginase activity
CJO11_RS03840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO11_RS03845	COG0165	Argininosuccinate lyase
CJO11_RS03855	COG0019	diaminopimelate decarboxylase activity
CJO11_RS03860	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CJO11_RS03860	COG1648	precorrin-2 dehydrogenase activity
CJO11_RS03865	COG0745	RESPONSE REGULATOR receiver
CJO11_RS03880	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CJO11_RS03900	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CJO11_RS03905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CJO11_RS03910	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CJO11_RS03920	COG0438	transferase activity, transferring glycosyl groups
CJO11_RS03930	COG1695	Transcriptional regulator
CJO11_RS03935	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CJO11_RS03950	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CJO11_RS03965	COG0626	cystathionine gamma-synthase activity
CJO11_RS03970	COG0668	transmembrane transport
CJO11_RS03975	COG1648	precorrin-2 dehydrogenase activity
CJO11_RS03975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CJO11_RS03995	COG0175	sulfate reduction
CJO11_RS04010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CJO11_RS04015	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CJO11_RS04020	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CJO11_RS04040	COG0670	Belongs to the BI1 family
CJO11_RS04045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CJO11_RS04065	COG0849	cell division
CJO11_RS04070	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CJO11_RS04075	COG1181	Belongs to the D-alanine--D-alanine ligase family
CJO11_RS04080	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CJO11_RS04085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CJO11_RS04090	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CJO11_RS04100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CJO11_RS04105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJO11_RS04110	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CJO11_RS04115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CJO11_RS04130	COG0275	rRNA processing
CJO11_RS04135	COG2001	Belongs to the MraZ family
CJO11_RS04150	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJO11_RS04170	COG2154	pterin-4-alpha-carbinolamine dehydratase
CJO11_RS04175	COG4133	protoheme IX ABC transporter activity
CJO11_RS04180	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CJO11_RS04190	COG0024	Methionine aminopeptidase
CJO11_RS04200	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CJO11_RS04210	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CJO11_RS04215	COG0347	Belongs to the P(II) protein family
CJO11_RS04220	COG0174	glutamine synthetase
CJO11_RS04245	COG0729	surface antigen
CJO11_RS04250	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CJO11_RS04255	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CJO11_RS04260	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CJO11_RS04305	COG1733	regulation of RNA biosynthetic process
CJO11_RS04340	COG0271	Belongs to the BolA IbaG family
CJO11_RS04345	COG1741	Belongs to the pirin family
CJO11_RS04350	COG0300	oxidoreductase activity
CJO11_RS04355	COG0596	Alpha beta hydrolase
CJO11_RS04370	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CJO11_RS04375	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CJO11_RS04380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJO11_RS04385	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CJO11_RS04390	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CJO11_RS04405	COG1946	Acyl-CoA thioesterase
CJO11_RS04415	COG5001	Diguanylate cyclase
CJO11_RS04415	COG5002	protein histidine kinase activity
CJO11_RS04425	COG0776	regulation of translation
CJO11_RS04430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CJO11_RS04435	COG0416	fatty acid biosynthetic process
CJO11_RS04440	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CJO11_RS04450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CJO11_RS04480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJO11_RS04485	COG0215	cysteine-tRNA ligase activity
CJO11_RS04500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CJO11_RS04515	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CJO11_RS04520	COG0625	glutathione transferase activity
CJO11_RS04530	COG2169	Transcriptional regulator
CJO11_RS04530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJO11_RS04550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CJO11_RS04555	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CJO11_RS04560	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CJO11_RS04565	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CJO11_RS04570	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJO11_RS04595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CJO11_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS04625	COG1045	serine acetyltransferase
CJO11_RS04630	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJO11_RS04640	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CJO11_RS04645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CJO11_RS04650	COG2020	methyltransferase activity
CJO11_RS04655	COG0105	UTP biosynthetic process
CJO11_RS04665	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CJO11_RS04675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CJO11_RS04680	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CJO11_RS04685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CJO11_RS04700	COG3724	N-succinylarginine dihydrolase activity
CJO11_RS04715	COG1970	mechanosensitive ion channel activity
CJO11_RS04725	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CJO11_RS04755	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CJO11_RS04765	COG0640	Transcriptional regulator
CJO11_RS04780	COG1278	Cold shock
CJO11_RS04790	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CJO11_RS04795	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CJO11_RS04810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJO11_RS04825	COG0625	glutathione transferase activity
CJO11_RS04830	COG0295	cytidine deaminase activity
CJO11_RS04840	COG5328	Belongs to the UPF0262 family
CJO11_RS04845	COG0305	Participates in initiation and elongation during chromosome replication
CJO11_RS04855	COG1758	RNA polymerase activity
CJO11_RS04860	COG2894	cell division
CJO11_RS04875	COG1482	cell wall glycoprotein biosynthetic process
CJO11_RS04880	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CJO11_RS04880	COG0662	Cupin 2, conserved barrel domain protein
CJO11_RS04900	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CJO11_RS04930	COG0175	sulfate reduction
CJO11_RS04945	COG1218	3'(2'),5'-bisphosphate nucleotidase
CJO11_RS04965	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CJO11_RS04980	COG2866	Carboxypeptidase
CJO11_RS05005	COG4771	TonB-dependent receptor
CJO11_RS05015	COG0745	RESPONSE REGULATOR receiver
CJO11_RS05025	COG0800	Aldolase
CJO11_RS05030	COG0837	glucose binding
CJO11_RS05035	COG0129	dihydroxy-acid dehydratase activity
CJO11_RS05040	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CJO11_RS05055	COG0418	dihydroorotase activity
CJO11_RS05060	COG0354	folic acid binding
CJO11_RS05075	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS05080	COG1024	Enoyl-CoA hydratase
CJO11_RS05085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CJO11_RS05090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CJO11_RS05095	COG2989	Protein conserved in bacteria
CJO11_RS05120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CJO11_RS05125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CJO11_RS05130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CJO11_RS05135	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CJO11_RS05145	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CJO11_RS05150	COG0583	DNA-binding transcription factor activity
CJO11_RS05190	COG0538	isocitrate dehydrogenase activity
CJO11_RS05205	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CJO11_RS05210	COG4106	trans-aconitate 2-methyltransferase activity
CJO11_RS05215	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CJO11_RS05230	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CJO11_RS05245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CJO11_RS05250	COG0741	lytic transglycosylase activity
CJO11_RS05270	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CJO11_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS05285	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
CJO11_RS05290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CJO11_RS05295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CJO11_RS05300	COG0534	Mate efflux family protein
CJO11_RS05310	COG0137	argininosuccinate synthase activity
CJO11_RS05335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJO11_RS05355	COG0028	Belongs to the TPP enzyme family
CJO11_RS05360	COG3590	peptidase
CJO11_RS05365	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CJO11_RS05375	COG0339	signal peptide processing
CJO11_RS05380	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CJO11_RS05395	COG4206	TonB-dependent receptor
CJO11_RS05410	COG5001	Diguanylate cyclase
CJO11_RS05415	COG0039	L-malate dehydrogenase activity
CJO11_RS05420	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CJO11_RS05430	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO11_RS05435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJO11_RS05440	COG0154	amidase activity
CJO11_RS05445	COG2860	membrane
CJO11_RS05460	COG0203	ribosomal protein L17
CJO11_RS05465	COG0202	RNA polymerase activity
CJO11_RS05470	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CJO11_RS05475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CJO11_RS05485	COG0563	adenylate kinase activity
CJO11_RS05490	COG0201	protein transport
CJO11_RS05495	COG0200	Binds to the 23S rRNA
CJO11_RS05500	COG1841	ribosomal large subunit assembly
CJO11_RS05505	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CJO11_RS05510	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CJO11_RS05515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CJO11_RS05520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CJO11_RS05525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJO11_RS05530	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CJO11_RS05535	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CJO11_RS05540	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CJO11_RS05545	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CJO11_RS05550	COG0255	Belongs to the universal ribosomal protein uL29 family
CJO11_RS05555	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CJO11_RS05560	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CJO11_RS05565	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CJO11_RS05570	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CJO11_RS05575	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CJO11_RS05580	COG0089	rRNA binding
CJO11_RS05585	COG0088	Forms part of the polypeptide exit tunnel
CJO11_RS05590	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CJO11_RS05595	COG0051	transcription antitermination factor activity, RNA binding
CJO11_RS05600	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CJO11_RS05605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CJO11_RS05610	COG0049	tRNA binding
CJO11_RS05615	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CJO11_RS05655	COG0456	acetyltransferase
CJO11_RS05660	COG0784	Response regulator, receiver
CJO11_RS05665	COG0784	Response regulator, receiver
CJO11_RS05670	COG3920	Histidine kinase
CJO11_RS05700	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CJO11_RS05705	COG3813	Protein conserved in bacteria
CJO11_RS05710	COG0352	thiamine-phosphate diphosphorylase activity
CJO11_RS05710	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CJO11_RS05710	COG0351	phosphomethylpyrimidine kinase
CJO11_RS05715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CJO11_RS05730	COG0028	Belongs to the TPP enzyme family
CJO11_RS05740	COG5001	Diguanylate cyclase
CJO11_RS05740	COG3300	MHYT domain
CJO11_RS05745	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CJO11_RS05750	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJO11_RS05755	COG0552	protein localization to endoplasmic reticulum
CJO11_RS05760	COG2917	probably involved in intracellular septation
CJO11_RS05775	COG3158	transport of potassium into the cell
CJO11_RS05785	COG3088	subunit of a heme lyase
CJO11_RS05790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJO11_RS05795	COG1138	Cytochrome C-type biogenesis protein
CJO11_RS05800	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
CJO11_RS05805	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CJO11_RS05825	COG0254	rRNA binding
CJO11_RS05830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CJO11_RS05840	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CJO11_RS05845	COG0750	zinc metalloprotease
CJO11_RS05850	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CJO11_RS05860	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CJO11_RS05865	COG0233	cytoplasmic translational termination
CJO11_RS05870	COG0528	UMP kinase activity
CJO11_RS05875	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CJO11_RS05880	COG0052	Belongs to the universal ribosomal protein uS2 family
CJO11_RS05895	COG0688	phosphatidylethanolamine metabolic process
CJO11_RS05915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJO11_RS05935	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CJO11_RS05955	COG1643	Atp-dependent helicase
CJO11_RS05960	COG0142	geranyltranstransferase activity
CJO11_RS05965	COG0287	Prephenate dehydrogenase
CJO11_RS05965	COG1605	Chorismate mutase
CJO11_RS05990	COG0488	(ABC) transporter
CJO11_RS06010	COG0438	transferase activity, transferring glycosyl groups
CJO11_RS06015	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJO11_RS06020	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CJO11_RS06025	COG1862	Preprotein translocase
CJO11_RS06065	COG1874	Beta-galactosidase
CJO11_RS06105	COG0800	Aldolase
CJO11_RS06110	COG3734	2-keto-3-deoxy-galactonokinase
CJO11_RS06140	COG0129	dihydroxy-acid dehydratase activity
CJO11_RS06150	COG2186	Transcriptional regulator
CJO11_RS06155	COG3250	beta-galactosidase activity
CJO11_RS06160	COG3534	alpha-L-arabinofuranosidase
CJO11_RS06170	COG3940	Belongs to the glycosyl hydrolase 43 family
CJO11_RS06230	COG4774	siderophore transport
CJO11_RS06260	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CJO11_RS06280	COG0066	3-isopropylmalate dehydratase activity
CJO11_RS06290	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CJO11_RS06310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CJO11_RS06315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJO11_RS06325	COG2226	methyltransferase
CJO11_RS06335	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CJO11_RS06340	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJO11_RS06345	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CJO11_RS06355	COG1024	Enoyl-CoA hydratase
CJO11_RS06380	COG1376	ErfK ybiS ycfS ynhG family protein
CJO11_RS06385	COG0037	tRNA processing
CJO11_RS06420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CJO11_RS06445	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CJO11_RS06460	COG1902	pentaerythritol trinitrate reductase activity
CJO11_RS06470	COG0321	lipoyl(octanoyl) transferase activity
CJO11_RS06500	COG4774	siderophore transport
CJO11_RS06505	COG2080	2 iron, 2 sulfur cluster binding
CJO11_RS06515	COG1058	Belongs to the CinA family
CJO11_RS06515	COG1546	Belongs to the CinA family
CJO11_RS06520	COG0081	regulation of translation
CJO11_RS06525	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CJO11_RS06595	COG2137	regulation of response to DNA damage stimulus
CJO11_RS06600	COG0318	PFAM AMP-dependent synthetase and ligase
CJO11_RS06635	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS06645	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS06650	COG2267	carboxylic ester hydrolase activity
CJO11_RS06665	COG0235	Class ii aldolase
CJO11_RS06670	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS06675	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CJO11_RS06680	COG1024	Enoyl-CoA hydratase
CJO11_RS06685	COG0183	Belongs to the thiolase family
CJO11_RS06710	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CJO11_RS06715	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CJO11_RS06720	COG0438	transferase activity, transferring glycosyl groups
CJO11_RS06770	COG2755	lipolytic protein G-D-S-L family
CJO11_RS06770	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CJO11_RS06785	COG1696	Membrane protein involved in D-alanine export
CJO11_RS06820	COG1132	(ABC) transporter
CJO11_RS06870	COG1609	Transcriptional regulator
CJO11_RS06880	COG0366	Alpha amylase catalytic
CJO11_RS06900	COG5410	chromosome segregation
CJO11_RS06915	COG3588	fructose-bisphosphate aldolase
CJO11_RS06945	COG0800	Aldolase
CJO11_RS06950	COG3734	2-keto-3-deoxy-galactonokinase
CJO11_RS06955	COG1012	belongs to the aldehyde dehydrogenase family
CJO11_RS06975	COG2271	Major facilitator Superfamily
CJO11_RS06980	COG4948	Mandelate Racemase Muconate Lactonizing
CJO11_RS06990	COG2814	Major facilitator Superfamily
CJO11_RS07000	COG3386	PFAM SMP-30 Gluconolaconase
CJO11_RS07005	COG4948	Mandelate Racemase Muconate Lactonizing
CJO11_RS07010	COG1063	alcohol dehydrogenase
CJO11_RS07015	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS07030	COG2271	Major facilitator Superfamily
CJO11_RS07080	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CJO11_RS07080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJO11_RS07085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJO11_RS07090	COG4638	Rieske (2fe-2S)
CJO11_RS07095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CJO11_RS07095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CJO11_RS07110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CJO11_RS07120	COG0489	protein tyrosine kinase activity
CJO11_RS07125	COG0330	HflC and HflK could
CJO11_RS07130	COG0330	HflC and HflK could
CJO11_RS07160	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CJO11_RS07170	COG0746	molybdenum cofactor guanylyltransferase activity
CJO11_RS07175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CJO11_RS07185	COG0085	RNA polymerase activity
CJO11_RS07195	COG3655	Transcriptional regulator
CJO11_RS07200	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CJO11_RS07205	COG0222	ribosome binding
CJO11_RS07225	COG0534	Mate efflux family protein
CJO11_RS07230	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CJO11_RS07235	COG0459	protein refolding
CJO11_RS07240	COG0531	amino acid
CJO11_RS07260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJO11_RS07260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CJO11_RS07265	COG3920	Histidine kinase
CJO11_RS07275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJO11_RS07300	COG2070	2-Nitropropane dioxygenase
CJO11_RS07305	COG2814	Major facilitator Superfamily
CJO11_RS07310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CJO11_RS07315	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CJO11_RS07325	COG2890	protein-(glutamine-N5) methyltransferase activity
CJO11_RS07330	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CJO11_RS07335	COG0124	histidyl-tRNA synthetase
CJO11_RS07345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CJO11_RS07350	COG0312	modulator of DNA gyrase
CJO11_RS07360	COG1137	ATPase activity
CJO11_RS07365	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CJO11_RS07380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJO11_RS07390	COG0156	8-amino-7-oxononanoate synthase activity
CJO11_RS07445	COG4166	transmembrane transport
CJO11_RS07455	COG3483	tryptophan 2,3-dioxygenase activity
CJO11_RS07460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO11_RS07475	COG2226	methyltransferase
CJO11_RS07485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJO11_RS07500	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO11_RS07515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CJO11_RS07520	COG0281	malic enzyme
CJO11_RS07520	COG0280	phosphate acetyltransferase
CJO11_RS07530	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CJO11_RS07560	COG4695	Portal protein
CJO11_RS07640	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CJO11_RS07640	COG2885	chlorophyll binding
CJO11_RS07650	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CJO11_RS07665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CJO11_RS07670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CJO11_RS07675	COG1278	Cold shock
CJO11_RS07680	COG1253	flavin adenine dinucleotide binding
CJO11_RS07705	COG0004	ammonium transporteR
CJO11_RS07710	COG0347	Belongs to the P(II) protein family
CJO11_RS07725	COG0308	aminopeptidase N
CJO11_RS07745	COG0564	pseudouridine synthase activity
CJO11_RS07755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CJO11_RS07770	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJO11_RS07770	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CJO11_RS07815	COG0183	Belongs to the thiolase family
CJO11_RS07820	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CJO11_RS07830	COG1329	Transcriptional regulator
CJO11_RS07835	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CJO11_RS07850	COG1196	nuclear chromosome segregation
CJO11_RS07850	COG0739	heme binding
CJO11_RS07850	COG0741	lytic transglycosylase activity
CJO11_RS07855	COG0113	porphobilinogen synthase activity
CJO11_RS07860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CJO11_RS07875	COG1872	DUF167
CJO11_RS07900	COG0604	alcohol dehydrogenase
CJO11_RS07900	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS07900	COG3321	synthase
CJO11_RS07915	COG0438	transferase activity, transferring glycosyl groups
CJO11_RS07925	COG0318	PFAM AMP-dependent synthetase and ligase
CJO11_RS07935	COG0739	heme binding
CJO11_RS07940	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CJO11_RS07945	COG0667	Aldo Keto reductase
CJO11_RS07950	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CJO11_RS07955	COG0799	negative regulation of ribosome biogenesis
CJO11_RS07960	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CJO11_RS07970	COG0793	Belongs to the peptidase S41A family
CJO11_RS07980	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CJO11_RS07995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CJO11_RS08050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CJO11_RS08070	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CJO11_RS08090	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CJO11_RS08095	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
CJO11_RS08100	COG1295	ribonuclease BN
CJO11_RS08105	COG0484	heat shock protein binding
CJO11_RS08110	COG0259	pyridoxamine-phosphate oxidase activity
CJO11_RS08135	COG0482	sulfurtransferase activity
CJO11_RS08155	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJO11_RS08170	COG4152	abc transporter atp-binding protein
CJO11_RS08175	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CJO11_RS08190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CJO11_RS08220	COG3540	Alkaline phosphatase
CJO11_RS08225	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CJO11_RS08235	COG2957	Belongs to the agmatine deiminase family
CJO11_RS08240	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CJO11_RS08245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CJO11_RS08250	COG2833	Protein of unknown function (DUF455)
CJO11_RS08255	COG0739	heme binding
CJO11_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS08295	COG0495	leucyl-tRNA aminoacylation
CJO11_RS08330	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CJO11_RS08350	COG0067	glutamate synthase
CJO11_RS08350	COG0070	glutamate synthase
CJO11_RS08350	COG0069	glutamate synthase activity
CJO11_RS08360	COG0438	transferase activity, transferring glycosyl groups
CJO11_RS08375	COG0183	Belongs to the thiolase family
CJO11_RS08395	COG1132	(ABC) transporter
CJO11_RS08400	COG1968	undecaprenyl-diphosphatase activity
CJO11_RS08415	COG3186	Phenylalanine-4-hydroxylase
CJO11_RS08420	COG0009	L-threonylcarbamoyladenylate synthase
CJO11_RS08425	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS08440	COG1956	GAF domain-containing protein
CJO11_RS08480	COG0357	Ribosomal RNA small subunit methyltransferase G
CJO11_RS08485	COG0445	tRNA wobble uridine modification
CJO11_RS08490	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CJO11_RS08505	COG0069	glutamate synthase activity
CJO11_RS08505	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CJO11_RS08525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CJO11_RS08530	COG1981	membrane
CJO11_RS08535	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CJO11_RS08540	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CJO11_RS08545	COG0424	maF-like protein
CJO11_RS08550	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJO11_RS08555	COG0237	dephospho-CoA kinase activity
CJO11_RS08560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CJO11_RS08565	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CJO11_RS08595	COG0316	Belongs to the HesB IscA family
CJO11_RS08635	COG3275	phosphorelay sensor kinase activity
CJO11_RS08710	COG3275	phosphorelay sensor kinase activity
CJO11_RS08715	COG3279	Response regulator of the LytR AlgR family
CJO11_RS08730	COG0590	tRNA wobble adenosine to inosine editing
CJO11_RS08735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CJO11_RS08755	COG1570	exodeoxyribonuclease VII activity
CJO11_RS08760	COG0151	Belongs to the GarS family
CJO11_RS08765	COG2814	Major facilitator Superfamily
CJO11_RS08775	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJO11_RS08790	COG0316	Belongs to the HesB IscA family
CJO11_RS08800	COG2151	metal-sulfur cluster biosynthetic enzyme
CJO11_RS08805	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CJO11_RS08810	COG0719	Fe-S assembly protein
CJO11_RS08815	COG0396	ATPase activity
CJO11_RS08835	COG0719	Fe-S assembly protein
CJO11_RS08850	COG0167	dihydroorotate dehydrogenase activity
CJO11_RS08855	COG0405	Gamma-glutamyltransferase
CJO11_RS08860	COG1022	Amp-dependent synthetase and ligase
CJO11_RS08875	COG2022	thiamine diphosphate biosynthetic process
CJO11_RS08885	COG1612	heme a metabolic process
CJO11_RS08895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CJO11_RS08900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CJO11_RS08925	COG1215	transferase activity, transferring glycosyl groups
CJO11_RS08950	COG0318	PFAM AMP-dependent synthetase and ligase
CJO11_RS08955	COG1473	amidohydrolase
CJO11_RS08970	COG0138	bifunctional purine biosynthesis protein purh
CJO11_RS08980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJO11_RS08995	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CJO11_RS09015	COG3104	oligopeptide transport
CJO11_RS09020	COG2188	Transcriptional regulator
CJO11_RS09040	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
CJO11_RS09055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO11_RS09065	COG2733	membrane
CJO11_RS09085	COG2086	electron transfer activity
CJO11_RS09090	COG0045	succinate-CoA ligase (ADP-forming) activity
CJO11_RS09095	COG1218	3'(2'),5'-bisphosphate nucleotidase
CJO11_RS09105	COG1253	flavin adenine dinucleotide binding
CJO11_RS09115	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CJO11_RS09120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CJO11_RS09125	COG0196	riboflavin kinase activity
CJO11_RS09130	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CJO11_RS09135	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CJO11_RS09140	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CJO11_RS09145	COG0588	phosphoglycerate mutase activity
CJO11_RS09170	COG0308	aminopeptidase N
CJO11_RS09175	COG1496	oxidoreductase activity
CJO11_RS09180	COG0723	plastoquinol--plastocyanin reductase activity
CJO11_RS09185	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CJO11_RS09195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CJO11_RS09210	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CJO11_RS09215	COG1192	Involved in chromosome partitioning
CJO11_RS09235	COG1201	RNA secondary structure unwinding
CJO11_RS09280	COG1494	fructose-1,6-bisphosphatase
CJO11_RS09300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CJO11_RS09305	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CJO11_RS09320	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CJO11_RS09325	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CJO11_RS09340	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CJO11_RS09345	COG0072	phenylalanine-tRNA ligase activity
CJO11_RS09350	COG4221	oxidoreductase activity
CJO11_RS09355	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CJO11_RS09360	COG2205	protein histidine kinase activity
CJO11_RS09405	COG0671	phosphoesterase, PA-phosphatase related
CJO11_RS09415	COG1215	transferase activity, transferring glycosyl groups
CJO11_RS09450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CJO11_RS09455	COG2091	lysine biosynthetic process via aminoadipic acid
CJO11_RS09460	COG2244	polysaccharide biosynthetic process
CJO11_RS09480	COG0489	protein tyrosine kinase activity
CJO11_RS09480	COG3206	protein involved in exopolysaccharide biosynthesis
CJO11_RS09490	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJO11_RS09500	COG2197	response regulator
CJO11_RS09525	COG0596	Alpha beta hydrolase
CJO11_RS09535	COG3119	arylsulfatase activity
CJO11_RS09555	COG2814	Major facilitator Superfamily
CJO11_RS09560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CJO11_RS09605	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJO11_RS09640	COG0717	Belongs to the dCTP deaminase family
CJO11_RS09645	COG3268	Saccharopine dehydrogenase
CJO11_RS09650	COG4771	TonB-dependent receptor
CJO11_RS09745	COG3118	belongs to the thioredoxin family
CJO11_RS09755	COG2095	MarC family integral membrane protein
CJO11_RS09765	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CJO11_RS09775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CJO11_RS09825	COG3104	oligopeptide transport
CJO11_RS09840	COG1131	(ABC) transporter
CJO11_RS09850	COG0312	modulator of DNA gyrase
CJO11_RS09870	COG2271	Major facilitator Superfamily
CJO11_RS09895	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CJO11_RS09895	COG0519	Catalyzes the synthesis of GMP from XMP
CJO11_RS09935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CJO11_RS09940	COG2824	Alkylphosphonate utilization operon protein PhnA
CJO11_RS09945	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS09950	COG1125	glycine betaine transport
CJO11_RS09965	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CJO11_RS09975	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CJO11_RS09985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CJO11_RS10020	COG0686	Belongs to the AlaDH PNT family
CJO11_RS10030	COG2884	Cell division ATP-binding protein ftsE
CJO11_RS10050	COG0287	Prephenate dehydrogenase
CJO11_RS10055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CJO11_RS10060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CJO11_RS10065	COG2813	Specifically methylates the guanine in position
CJO11_RS10065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CJO11_RS10070	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
CJO11_RS10070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CJO11_RS10080	COG2166	iron-sulfur cluster assembly
CJO11_RS10120	COG1842	Phage shock protein A
CJO11_RS10125	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CJO11_RS10130	COG0779	Required for maturation of 30S ribosomal subunits
CJO11_RS10145	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CJO11_RS10160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CJO11_RS10175	COG1435	thymidine kinase activity
CJO11_RS10185	COG1994	Peptidase M50
CJO11_RS10190	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CJO11_RS10195	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CJO11_RS10200	COG1185	polyribonucleotide nucleotidyltransferase activity
CJO11_RS10220	COG0842	Transport permease protein
CJO11_RS10240	COG4638	Rieske (2fe-2S)
CJO11_RS10245	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CJO11_RS10250	COG0022	dehydrogenase e1 component
CJO11_RS10255	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJO11_RS10280	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS10285	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CJO11_RS10290	COG0022	dehydrogenase e1 component
CJO11_RS10310	COG4638	Rieske (2fe-2S)
CJO11_RS10330	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS10345	COG0183	Belongs to the thiolase family
CJO11_RS10355	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS10370	COG2130	NADP-dependent
CJO11_RS10380	COG2130	NADP-dependent
CJO11_RS10395	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS10400	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS10405	COG1053	succinate dehydrogenase
CJO11_RS10445	COG4638	Rieske (2fe-2S)
CJO11_RS10450	COG2130	NADP-dependent
CJO11_RS10455	COG1940	carbohydrate kinase activity
CJO11_RS10475	COG1595	DNA-templated transcription, initiation
CJO11_RS10505	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CJO11_RS10550	COG1472	Belongs to the glycosyl hydrolase 3 family
CJO11_RS10575	COG4566	intracellular signal transduction
CJO11_RS10580	COG3264	Mechanosensitive ion channel
CJO11_RS10580	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CJO11_RS10650	COG1448	Aminotransferase
CJO11_RS10670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJO11_RS10670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CJO11_RS10685	COG2983	Belongs to the UPF0260 family
CJO11_RS10690	COG1999	signal sequence binding
CJO11_RS10715	COG0629	single-stranded DNA binding
CJO11_RS10735	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CJO11_RS10740	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CJO11_RS10750	COG0457	Tetratricopeptide repeat
CJO11_RS10755	COG4773	Receptor
CJO11_RS10760	COG5265	(ABC) transporter
CJO11_RS10805	COG0583	DNA-binding transcription factor activity
CJO11_RS10820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CJO11_RS10840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CJO11_RS10860	COG1024	Enoyl-CoA hydratase
CJO11_RS10860	COG1250	3-hydroxyacyl-CoA dehydrogenase
CJO11_RS10870	COG0318	PFAM AMP-dependent synthetase and ligase
CJO11_RS10880	COG4771	TonB-dependent receptor
CJO11_RS10890	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS10895	COG2211	Major facilitator Superfamily
CJO11_RS10900	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS10905	COG1028	Short-chain dehydrogenase reductase Sdr
CJO11_RS10920	COG1960	acyl-CoA dehydrogenase activity
CJO11_RS10930	COG3743	rRNA binding
CJO11_RS10930	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CJO11_RS10940	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CJO11_RS10945	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CJO11_RS10950	COG0181	hydroxymethylbilane synthase activity
CJO11_RS10965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CJO11_RS10985	COG0556	nucleotide-excision repair
CJO11_RS11000	COG2226	methyltransferase
CJO11_RS11000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CJO11_RS11000	COG0596	Alpha beta hydrolase
CJO11_RS11005	COG2308	Evidence 4 Homologs of previously reported genes of
CJO11_RS11015	COG1305	Transglutaminase-like
CJO11_RS11025	COG4566	intracellular signal transduction
CJO11_RS11035	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CJO11_RS11040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CJO11_RS11090	COG1217	gtp-binding protein TYPA
CJO11_RS11095	COG4771	TonB-dependent receptor
CJO11_RS11100	COG3152	Membrane
CJO11_RS11110	COG4181	ATPase activity
CJO11_RS11120	COG1381	Involved in DNA repair and RecF pathway recombination
CJO11_RS11125	COG0473	3-isopropylmalate dehydrogenase activity
CJO11_RS11135	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CJO11_RS11150	COG0730	response to heat
CJO11_RS11170	COG0525	valine-tRNA ligase activity
CJO11_RS11175	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CJO11_RS11180	COG1127	ABC transporter
CJO11_RS11215	COG0546	phosphoglycolate phosphatase activity
CJO11_RS11230	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CJO11_RS11235	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CJO11_RS11250	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CJO11_RS11255	COG0154	amidase activity
CJO11_RS11260	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CJO11_RS11275	COG0612	Peptidase, M16
CJO11_RS11315	COG0183	Belongs to the thiolase family
CJO11_RS11325	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CJO11_RS11330	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CJO11_RS11335	COG1846	Transcriptional regulator
CJO11_RS11360	COG4964	Belongs to the GSP D family
CJO11_RS11380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CJO11_RS11380	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CJO11_RS11385	COG3422	double-strand break repair
CJO11_RS11390	COG0328	RNA-DNA hybrid ribonuclease activity
CJO11_RS11395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CJO11_RS11400	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CJO11_RS11410	COG0018	arginyl-trna synthetase
CJO11_RS11425	COG1472	Belongs to the glycosyl hydrolase 3 family
CJO11_RS11430	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CJO11_RS11435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CJO11_RS11440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJO11_RS11445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CJO11_RS11450	COG0805	protein transport
CJO11_RS11470	COG1937	Protein conserved in bacteria
CJO11_RS11475	COG2132	Multicopper oxidase
CJO11_RS11525	COG0783	Belongs to the Dps family
CJO11_RS11535	COG0494	nUDIX hydrolase
CJO11_RS11545	COG2814	Major facilitator Superfamily
CJO11_RS11550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CJO11_RS11595	COG0745	RESPONSE REGULATOR receiver
CJO11_RS11610	COG2072	flavoprotein involved in K transport
CJO11_RS11620	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CJO11_RS11670	COG3243	poly(R)-hydroxyalkanoic acid synthase
CJO11_RS11675	COG0436	Aminotransferase
CJO11_RS11700	COG0745	RESPONSE REGULATOR receiver
CJO11_RS11725	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
CJO11_RS11730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CJO11_RS11740	COG0640	Transcriptional regulator
CJO11_RS11755	COG0646	methionine synthase
CJO11_RS11755	COG1410	methionine synthase
CJO11_RS11760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CJO11_RS11770	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJO11_RS11775	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CJO11_RS11815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CJO11_RS11820	COG5001	Diguanylate cyclase
CJO11_RS11825	COG0047	phosphoribosylformylglycinamidine synthase activity
CJO11_RS11830	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJO11_RS11835	COG0612	Peptidase, M16
CJO11_RS11845	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CJO11_RS11870	COG0424	maF-like protein
CJO11_RS11875	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CJO11_RS11885	COG1192	Involved in chromosome partitioning
CJO11_RS11890	COG2226	methyltransferase
CJO11_RS11890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CJO11_RS11890	COG0596	Alpha beta hydrolase
CJO11_RS11900	COG0531	amino acid
CJO11_RS11905	COG0322	excinuclease ABC activity
CJO11_RS11935	COG0659	secondary active sulfate transmembrane transporter activity
CJO11_RS11940	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CJO11_RS11955	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CJO11_RS11960	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CJO11_RS11965	COG0643	Histidine kinase
CJO11_RS11965	COG2198	Histidine kinase
CJO11_RS11975	COG0745	RESPONSE REGULATOR receiver
CJO11_RS11980	COG2201	protein-glutamate methylesterase activity
CJO11_RS11985	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CJO11_RS11990	COG5001	Diguanylate cyclase
CJO11_RS12045	COG0616	signal peptide processing
CJO11_RS12050	COG0540	Belongs to the ATCase OTCase family
CJO11_RS12055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CJO11_RS12080	COG2311	Membrane
CJO11_RS12085	COG1160	GTP binding
CJO11_RS12105	COG0544	peptidyl-prolyl cis-trans isomerase activity
CJO11_RS12115	COG0154	amidase activity
CJO11_RS12125	COG0740	serine-type endopeptidase activity
CJO11_RS12130	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CJO11_RS12160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJO11_RS12165	COG0564	pseudouridine synthase activity
CJO11_RS12185	COG3023	N-Acetylmuramoyl-L-alanine amidase
CJO11_RS12190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CJO11_RS12200	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CJO11_RS12240	COG2967	ApaG domain
CJO11_RS12245	COG0248	Ppx GppA phosphatase
CJO11_RS12250	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CJO11_RS12260	COG1196	nuclear chromosome segregation
CJO11_RS12280	COG1194	a g-specific adenine glycosylase
CJO11_RS12295	COG2816	NAD+ diphosphatase activity
CJO11_RS12320	COG2239	Acts as a magnesium transporter
CJO11_RS12340	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CJO11_RS12350	COG1702	phosphate starvation-inducible protein PhoH
CJO11_RS12360	COG1012	belongs to the aldehyde dehydrogenase family
CJO11_RS12365	COG2945	thiolester hydrolase activity
CJO11_RS12365	COG0596	Alpha beta hydrolase
CJO11_RS12370	COG0438	transferase activity, transferring glycosyl groups
CJO11_RS12400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CJO11_RS12405	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CJO11_RS12415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CJO11_RS12420	COG0527	aspartate kinase activity
CJO11_RS12425	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CJO11_RS12460	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CJO11_RS12465	COG0594	ribonuclease P activity
CJO11_RS12470	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CJO11_RS12475	COG0706	membrane insertase activity
CJO11_RS12480	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CJO11_RS12495	COG0625	glutathione transferase activity
CJO11_RS12510	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJO11_RS12515	COG1301	dicarboxylic acid transport
CJO11_RS12525	COG0789	Transcriptional regulator
CJO11_RS12540	COG1199	ATP-dependent helicase activity
CJO11_RS12540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CJO11_RS12585	COG1047	Peptidyl-prolyl cis-trans
CJO11_RS12605	COG0489	protein tyrosine kinase activity
CJO11_RS12610	COG3302	dmso reductase anchor subunit
CJO11_RS12615	COG0437	4 iron, 4 sulfur cluster binding
CJO11_RS12620	COG0243	molybdopterin cofactor binding
CJO11_RS12630	COG0425	Belongs to the sulfur carrier protein TusA family
CJO11_RS12635	COG2210	Belongs to the sulfur carrier protein TusA family
CJO11_RS12640	COG0123	including yeast histone deacetylase and acetoin utilization protein
CJO11_RS12655	COG0095	Lipoate-protein ligase
CJO11_RS12680	COG0446	pyridine nucleotide-disulphide oxidoreductase
CJO11_RS12695	COG2048	Heterodisulfide reductase, subunit B
CJO11_RS12705	COG0509	glycine decarboxylation via glycine cleavage system
CJO11_RS12710	COG0640	Transcriptional regulator
CJO11_RS12730	COG0446	pyridine nucleotide-disulphide oxidoreductase
CJO11_RS12735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CJO11_RS12755	COG0640	Transcriptional regulator
CJO11_RS12760	COG0450	alkyl hydroperoxide reductase
CJO11_RS12785	COG2202	Pas domain
CJO11_RS12785	COG2205	protein histidine kinase activity
CJO11_RS12790	COG1522	sequence-specific DNA binding
CJO11_RS12800	COG0439	Biotin carboxylase
CJO11_RS12805	COG0511	ligase activity, forming carbon-carbon bonds
CJO11_RS12820	COG0101	tRNA pseudouridine synthase activity
CJO11_RS12825	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CJO11_RS12830	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CJO11_RS12835	COG0242	peptide deformylase activity
CJO11_RS12840	COG1322	Protein conserved in bacteria
CJO11_RS12855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJO11_RS12865	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJO11_RS12865	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJO11_RS12870	COG1660	Displays ATPase and GTPase activities
CJO11_RS12875	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CJO11_RS12880	COG2205	protein histidine kinase activity
CJO11_RS12885	COG0745	RESPONSE REGULATOR receiver
CJO11_RS12890	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CJO11_RS12910	COG2945	thiolester hydrolase activity
CJO11_RS12915	COG1104	cysteine desulfurase activity
CJO11_RS12920	COG1104	cysteine desulfurase activity
CJO11_RS12925	COG0633	Ferredoxin
CJO11_RS12940	COG2853	Lipoprotein
CJO11_RS12945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJO11_RS12955	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CJO11_RS12970	COG1278	Cold shock
CJO11_RS13020	COG1082	Xylose isomerase domain protein TIM barrel
CJO11_RS13025	COG0366	Alpha amylase catalytic
CJO11_RS13070	COG0739	heme binding
CJO11_RS13125	COG4964	Belongs to the GSP D family